BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= maV30164 (659 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_A7RGK5 Cluster: Predicted protein; n=4; Eumetazoa|Rep: ... 123 4e-27 UniRef50_O97166 Cluster: 3-alpha-hydroxysteroid dehydrogenase-li... 111 1e-23 UniRef50_P16152 Cluster: Carbonyl reductase [NADPH] 1 (EC 1.1.1.... 88 2e-16 UniRef50_A7SF98 Cluster: Predicted protein; n=1; Nematostella ve... 83 6e-15 UniRef50_A0E1K9 Cluster: Chromosome undetermined scaffold_73, wh... 83 6e-15 UniRef50_UPI0000E498BD Cluster: PREDICTED: similar to Carbonyl r... 82 1e-14 UniRef50_Q5DEH8 Cluster: SJCHGC00683 protein; n=2; Schistosoma|R... 81 3e-14 UniRef50_Q501A2 Cluster: At5g61830; n=8; Magnoliophyta|Rep: At5g... 77 4e-13 UniRef50_Q22DT5 Cluster: Oxidoreductase, short chain dehydrogena... 77 5e-13 UniRef50_UPI0000E494E7 Cluster: PREDICTED: similar to Carbonyl r... 75 2e-12 UniRef50_UPI0000E46681 Cluster: PREDICTED: similar to carbonyl r... 75 2e-12 UniRef50_Q01IF3 Cluster: H0306B06.2 protein; n=15; Magnoliophyta... 67 3e-10 UniRef50_Q233Z6 Cluster: Oxidoreductase, short chain dehydrogena... 67 4e-10 UniRef50_Q097P7 Cluster: Carbonyl reductase [NADPH] 1 (Nadph-dep... 65 1e-09 UniRef50_Q6H7D1 Cluster: Short-chain dehydrogenase/reductase pro... 48 1e-09 UniRef50_Q4L7K1 Cluster: Similar to 3(or 17)beta-hydroxysteroid ... 62 9e-09 UniRef50_Q22BQ2 Cluster: Oxidoreductase, short chain dehydrogena... 60 4e-08 UniRef50_Q00RH9 Cluster: OSIGBa0125M19.7 protein; n=12; Oryza sa... 59 8e-08 UniRef50_A4BA05 Cluster: Short chain dehydrogenase; n=1; Reineke... 59 1e-07 UniRef50_Q9LQ75 Cluster: T1N6.22 protein; n=13; core eudicotyled... 59 1e-07 UniRef50_Q4D5D5 Cluster: Short chain dehydrogenase, putative; n=... 58 1e-07 UniRef50_Q00RH3 Cluster: OSIGBa0125M19.13 protein; n=9; Oryza sa... 58 2e-07 UniRef50_Q3EZA6 Cluster: Short chain dehydrogenase; n=5; Bacilla... 57 4e-07 UniRef50_A0BZA9 Cluster: Chromosome undetermined scaffold_139, w... 57 4e-07 UniRef50_A0NL67 Cluster: Carbonyl reductase; n=2; Oenococcus oen... 56 8e-07 UniRef50_UPI00006CA45C Cluster: oxidoreductase, short chain dehy... 56 1e-06 UniRef50_Q28SS3 Cluster: Short-chain dehydrogenase/reductase SDR... 56 1e-06 UniRef50_A1ZM53 Cluster: Short chain dehydrogenase; n=1; Microsc... 56 1e-06 UniRef50_A7ANX9 Cluster: Putative uncharacterized protein; n=1; ... 55 1e-06 UniRef50_UPI00006CBD6F Cluster: oxidoreductase, short chain dehy... 54 2e-06 UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 54 2e-06 UniRef50_A7QKE7 Cluster: Chromosome chr2 scaffold_112, whole gen... 54 2e-06 UniRef50_Q7NNW5 Cluster: Glr0293 protein; n=6; Bacteria|Rep: Glr... 54 3e-06 UniRef50_A5B040 Cluster: Putative uncharacterized protein; n=1; ... 54 3e-06 UniRef50_A6EJ80 Cluster: Short chain dehydrogenase dehydrogenase... 54 4e-06 UniRef50_A2QT81 Cluster: Function: mouse WOX1 is an enhancer of ... 54 4e-06 UniRef50_UPI0000E476E0 Cluster: PREDICTED: similar to Carbonyl r... 41 5e-06 UniRef50_Q2W431 Cluster: Dehydrogenase with different specificit... 53 5e-06 UniRef50_A3WIM4 Cluster: Putative dehydrogenase; n=1; Idiomarina... 53 5e-06 UniRef50_A7IE62 Cluster: Short-chain dehydrogenase/reductase SDR... 53 7e-06 UniRef50_A4X6Z1 Cluster: Short-chain dehydrogenase/reductase SDR... 53 7e-06 UniRef50_A4QYV9 Cluster: Putative uncharacterized protein; n=1; ... 52 9e-06 UniRef50_A7PQQ5 Cluster: Chromosome chr6 scaffold_25, whole geno... 52 1e-05 UniRef50_Q5AWR2 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05 UniRef50_Q1VG25 Cluster: NAD-dependent epimerase/dehydratase:Sho... 51 2e-05 UniRef50_A4EYN4 Cluster: Putative uncharacterized protein; n=2; ... 50 4e-05 UniRef50_A4BUN6 Cluster: Short-chain dehydrogenase/reductase SDR... 50 5e-05 UniRef50_A2R3R8 Cluster: Contig An14c0180, complete genome; n=3;... 50 5e-05 UniRef50_Q03F37 Cluster: Short-chain dehydrogenase of various su... 50 7e-05 UniRef50_A1FW82 Cluster: Short-chain dehydrogenase/reductase SDR... 50 7e-05 UniRef50_A0M3M9 Cluster: Short-chain dehydrogenase/reductase fam... 49 9e-05 UniRef50_UPI0000D5685B Cluster: PREDICTED: similar to CG31235-PA... 49 1e-04 UniRef50_A0RXB6 Cluster: Short-chain alcohol dehydrogenase; n=2;... 48 2e-04 UniRef50_UPI000023D4D3 Cluster: hypothetical protein FG11091.1; ... 48 2e-04 UniRef50_Q1QYL7 Cluster: Short-chain dehydrogenase/reductase SDR... 48 2e-04 UniRef50_Q140F5 Cluster: Putative short-chain dehydrogenase/oxid... 48 2e-04 UniRef50_Q081K4 Cluster: Short-chain dehydrogenase/reductase SDR... 48 2e-04 UniRef50_A5FMQ3 Cluster: Short-chain dehydrogenase/reductase SDR... 48 2e-04 UniRef50_UPI00006CAF29 Cluster: oxidoreductase, short chain dehy... 48 3e-04 UniRef50_Q8YZV3 Cluster: NADPH-dependent carbonyl reductase; n=5... 48 3e-04 UniRef50_Q89V05 Cluster: Dehydrogenase; n=4; Proteobacteria|Rep:... 48 3e-04 UniRef50_A6D9G4 Cluster: Putative short-chain dehydrogenase/redu... 48 3e-04 UniRef50_A7RNX1 Cluster: Predicted protein; n=1; Nematostella ve... 48 3e-04 UniRef50_Q17CG7 Cluster: Short-chain dehydrogenase; n=2; Culicid... 47 3e-04 UniRef50_UPI0000D573DB Cluster: PREDICTED: similar to CG7675-PB,... 47 5e-04 UniRef50_A3CMH2 Cluster: Dehydrogenase, putative; n=1; Streptoco... 47 5e-04 UniRef50_A1ZT55 Cluster: Carbonyl reductase, NADPH 1; n=1; Micro... 47 5e-04 UniRef50_UPI000155BDDB Cluster: PREDICTED: similar to NADP+ depe... 46 6e-04 UniRef50_A6QK68 Cluster: Oxidoreductase; n=12; Staphylococcus au... 46 6e-04 UniRef50_Q4PDD2 Cluster: Putative uncharacterized protein; n=1; ... 46 6e-04 UniRef50_UPI0000D55E90 Cluster: PREDICTED: similar to CG11200-PB... 46 8e-04 UniRef50_Q8YW93 Cluster: Alr1722 protein; n=6; Bacteria|Rep: Alr... 46 8e-04 UniRef50_Q6F7B8 Cluster: Fatty acyl-CoA reductase; n=6; Moraxell... 46 8e-04 UniRef50_A7RSA6 Cluster: Predicted protein; n=1; Nematostella ve... 46 8e-04 UniRef50_Q4PDJ8 Cluster: Putative uncharacterized protein; n=1; ... 46 8e-04 UniRef50_P80365 Cluster: Corticosteroid 11-beta-dehydrogenase is... 46 8e-04 UniRef50_Q83D17 Cluster: Oxidoreductase, short-chain dehydrogena... 46 0.001 UniRef50_Q18SE9 Cluster: Short-chain dehydrogenase/reductase SDR... 46 0.001 UniRef50_Q12HC0 Cluster: Short-chain dehydrogenase/reductase SDR... 46 0.001 UniRef50_A1G528 Cluster: Short-chain dehydrogenase/reductase SDR... 46 0.001 UniRef50_Q1DUA6 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001 UniRef50_UPI0000587D40 Cluster: PREDICTED: similar to Retinol de... 45 0.001 UniRef50_UPI0000D5714C Cluster: PREDICTED: similar to CG2070-PA;... 45 0.002 UniRef50_UPI00004996DD Cluster: 3-oxoacyl-(acyl-carrier protein)... 45 0.002 UniRef50_Q2Y990 Cluster: Short-chain dehydrogenase/reductase SDR... 44 0.002 UniRef50_Q1IP06 Cluster: Short-chain dehydrogenase/reductase SDR... 44 0.002 UniRef50_A0JXQ7 Cluster: Short-chain dehydrogenase/reductase SDR... 44 0.002 UniRef50_Q48I17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 44 0.003 UniRef50_Q3A5G9 Cluster: Short-chain alcohol dehydrogenase-like ... 44 0.003 UniRef50_A6CZ65 Cluster: Short-chain dehydrogenase/reductase SDR... 44 0.003 UniRef50_Q869L6 Cluster: Similar to Lactococcus lactis (Subsp. l... 44 0.003 UniRef50_Q5CMZ5 Cluster: ENSANGP00000010899; n=2; Cryptosporidiu... 44 0.003 UniRef50_Q0UKX1 Cluster: Predicted protein; n=1; Phaeosphaeria n... 44 0.003 UniRef50_Q2S7V4 Cluster: Short-chain alcohol dehydrogenase-like ... 44 0.004 UniRef50_Q4YKD8 Cluster: Putative uncharacterized protein; n=2; ... 44 0.004 UniRef50_A0BRV4 Cluster: Chromosome undetermined scaffold_123, w... 44 0.004 UniRef50_Q2TWW2 Cluster: Dehydrogenases with different specifici... 44 0.004 UniRef50_Q0CKZ3 Cluster: Predicted protein; n=5; Pezizomycotina|... 44 0.004 UniRef50_A2R758 Cluster: Putative sequencing error; n=1; Aspergi... 44 0.004 UniRef50_UPI0000F2B793 Cluster: PREDICTED: similar to 17-beta hy... 43 0.006 UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -... 43 0.006 UniRef50_A5L8A4 Cluster: Short-chain dehydrogenase/reductase SDR... 43 0.006 UniRef50_A5K293 Cluster: Oxidoreductase, short-chain dehydrogena... 43 0.006 UniRef50_Q1PLL0 Cluster: 17-beta hydroxysteroid dehydrogenase 2;... 43 0.008 UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|R... 43 0.008 UniRef50_UPI0000E47A47 Cluster: PREDICTED: similar to serum lect... 42 0.010 UniRef50_UPI000038DA04 Cluster: COG1028: Dehydrogenases with dif... 42 0.010 UniRef50_Q8XAM8 Cluster: Putative fatty acyl chain reductase; n=... 42 0.010 UniRef50_Q5KW73 Cluster: 3-ketoacyl-[acyl carrier protein] reduc... 42 0.010 UniRef50_Q3JV89 Cluster: Putative uncharacterized protein; n=6; ... 42 0.010 UniRef50_Q2JGQ2 Cluster: Short-chain dehydrogenase/reductase SDR... 42 0.010 UniRef50_A7DM41 Cluster: Short-chain dehydrogenase/reductase SDR... 42 0.010 UniRef50_A6LY80 Cluster: Short-chain dehydrogenase/reductase SDR... 42 0.010 UniRef50_A4CX59 Cluster: Short-chain dehydrogenase/reductase (SD... 42 0.010 UniRef50_Q9L2C8 Cluster: Putative oxidoreductase; n=1; Streptomy... 42 0.013 UniRef50_Q1V1U2 Cluster: FabG-like protein; n=2; Candidatus Pela... 42 0.013 UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 42 0.013 UniRef50_Q5CAF5 Cluster: Neomenthol dehydrogenase; n=5; core eud... 42 0.013 UniRef50_A6SHG0 Cluster: Putative uncharacterized protein; n=1; ... 42 0.013 UniRef50_A6R5Y9 Cluster: Predicted protein; n=1; Ajellomyces cap... 42 0.013 UniRef50_Q8TP33 Cluster: Short chain dehydrogenase; n=1; Methano... 42 0.013 UniRef50_UPI00015B6097 Cluster: PREDICTED: similar to CG11200-PA... 42 0.017 UniRef50_A4XSH7 Cluster: Short-chain dehydrogenase/reductase SDR... 42 0.017 UniRef50_A7F9T5 Cluster: Putative uncharacterized protein; n=1; ... 42 0.017 UniRef50_Q2NGE1 Cluster: Predicted short chain dehydrogenase; n=... 42 0.017 UniRef50_Q53217 Cluster: Uncharacterized short-chain type dehydr... 42 0.017 UniRef50_Q5NZV3 Cluster: (S)-1-Phenylethanol dehydrogenase; n=4;... 41 0.023 UniRef50_Q1N3U9 Cluster: Short chain dehydrogenase; n=1; Oceanob... 41 0.023 UniRef50_A0PND0 Cluster: Oxidoreductase; n=4; Actinomycetales|Re... 41 0.023 UniRef50_A4QXZ6 Cluster: Putative uncharacterized protein; n=3; ... 41 0.023 UniRef50_UPI0000E47390 Cluster: PREDICTED: similar to retinol de... 41 0.030 UniRef50_A4WBV5 Cluster: Short-chain dehydrogenase/reductase SDR... 41 0.030 UniRef50_A3D6S9 Cluster: Short-chain dehydrogenase/reductase SDR... 41 0.030 UniRef50_A3CQN6 Cluster: Dehydrogenase, eukaryotic-like, putativ... 41 0.030 UniRef50_A4RF95 Cluster: Putative uncharacterized protein; n=1; ... 41 0.030 UniRef50_Q1VNC3 Cluster: Predicted short-chain dehydrogenase; n=... 40 0.040 UniRef50_Q15W58 Cluster: Short-chain dehydrogenase/reductase SDR... 40 0.040 UniRef50_Q7YWE8 Cluster: Normocyte binding protein 2b; n=19; Pla... 40 0.040 UniRef50_Q4U978 Cluster: Short-chain dehydrogenase/reductase (SD... 40 0.040 UniRef50_A6QU72 Cluster: Predicted protein; n=2; Onygenales|Rep:... 40 0.040 UniRef50_A1S135 Cluster: Short-chain dehydrogenase/reductase SDR... 40 0.040 UniRef50_Q9WYS2 Cluster: Oxidoreductase, short chain dehydrogena... 40 0.053 UniRef50_Q8EQH7 Cluster: Alcohol dehydrogenase; n=1; Oceanobacil... 40 0.053 UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain dehydrogena... 40 0.053 UniRef50_Q3WGZ8 Cluster: Short-chain dehydrogenase/reductase SDR... 40 0.053 UniRef50_Q26ER7 Cluster: Dehydrogenase/reductase; n=13; Bacteria... 40 0.053 UniRef50_Q03B39 Cluster: Carbonyl reductase; n=2; Bacilli|Rep: C... 40 0.053 UniRef50_A6EJT9 Cluster: Putative dehydrogenase; n=1; Pedobacter... 40 0.053 UniRef50_A3U1B5 Cluster: Putative short chain dehydrogenase; n=1... 40 0.053 UniRef50_A0UZI2 Cluster: Short-chain dehydrogenase/reductase SDR... 40 0.053 UniRef50_Q9LZA3 Cluster: Putative uncharacterized protein F8F6_2... 40 0.053 UniRef50_A7RYH1 Cluster: Predicted protein; n=7; Eumetazoa|Rep: ... 40 0.053 UniRef50_A4HMC2 Cluster: Putative uncharacterized protein; n=3; ... 40 0.053 UniRef50_A5DIM4 Cluster: Putative uncharacterized protein; n=1; ... 40 0.053 UniRef50_Q97A90 Cluster: DTDP-4-dehydrorhamnose reductase; n=1; ... 40 0.053 UniRef50_UPI000023CB35 Cluster: hypothetical protein FG03285.1; ... 40 0.070 UniRef50_O53537 Cluster: Possible oxidoreductase; n=9; cellular ... 40 0.070 UniRef50_Q1VHF4 Cluster: Probable oxidoreductase protein, short-... 40 0.070 UniRef50_A5UTC3 Cluster: Short-chain dehydrogenase/reductase SDR... 40 0.070 UniRef50_A4AT28 Cluster: Dehydrogenase; n=2; Flavobacteriales|Re... 40 0.070 UniRef50_A2FH32 Cluster: Oxidoreductase, short chain dehydrogena... 40 0.070 UniRef50_Q6CP24 Cluster: Similarities with sp|P40579 Saccharomyc... 40 0.070 UniRef50_UPI0000D9AA6B Cluster: PREDICTED: hypothetical protein;... 39 0.093 UniRef50_Q88ZF7 Cluster: Short-chain dehydrogenase/oxidoreductas... 39 0.093 UniRef50_Q7NJ27 Cluster: Gll2005 protein; n=3; Cyanobacteria|Rep... 39 0.093 UniRef50_Q3F0M6 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 39 0.093 UniRef50_Q2UF38 Cluster: Dehydrogenases with different specifici... 39 0.093 UniRef50_A6STP3 Cluster: Putative uncharacterized protein; n=1; ... 39 0.093 UniRef50_P36417 Cluster: G-box-binding factor; n=3; Dictyosteliu... 39 0.093 UniRef50_UPI00005873A1 Cluster: PREDICTED: hypothetical protein;... 39 0.12 UniRef50_UPI000045C012 Cluster: COG1028: Dehydrogenases with dif... 39 0.12 UniRef50_Q97DJ3 Cluster: Short-chain alcohol dehydrogenase famil... 39 0.12 UniRef50_A4WW43 Cluster: Putative uncharacterized protein; n=1; ... 39 0.12 UniRef50_A3PT80 Cluster: Short-chain dehydrogenase/reductase SDR... 39 0.12 UniRef50_A3ET57 Cluster: Short-chain alcohol dehydrogenase; n=2;... 39 0.12 UniRef50_Q7K0F7 Cluster: GH19857p; n=4; Diptera|Rep: GH19857p - ... 39 0.12 UniRef50_A2E0P5 Cluster: Oxidoreductase, short chain dehydrogena... 39 0.12 UniRef50_Q4J702 Cluster: Oxidoreductase; n=2; Sulfolobus|Rep: Ox... 39 0.12 UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 38 0.16 UniRef50_Q73PW1 Cluster: Oxidoreductase, short chain dehydrogena... 38 0.16 UniRef50_A3Y6H5 Cluster: Short chain dehydrogenase; n=4; Bacteri... 38 0.16 UniRef50_Q2QLP7 Cluster: Oxidoreductase, short chain dehydrogena... 38 0.16 UniRef50_A2R9D0 Cluster: Remark: during fruiting body developmen... 38 0.16 UniRef50_A1DNP7 Cluster: Short chain dehydrogenase/reductase fam... 38 0.16 UniRef50_Q8WVS4 Cluster: WD repeat-containing protein 60; n=24; ... 38 0.16 UniRef50_Q4D3W0 Cluster: Putative uncharacterized protein; n=4; ... 29 0.21 UniRef50_Q9RT30 Cluster: Oxidoreductase, short-chain dehydrogena... 38 0.21 UniRef50_Q2JY74 Cluster: Oxidoreductase, short chain dehydrogena... 38 0.21 UniRef50_Q1DE83 Cluster: Oxidoreductase, short chain dehydrogena... 38 0.21 UniRef50_A5GU52 Cluster: Putative uncharacterized protein SynRCC... 38 0.21 UniRef50_Q6NLR7 Cluster: At5g04070; n=4; Magnoliophyta|Rep: At5g... 38 0.21 UniRef50_Q0UF48 Cluster: Putative uncharacterized protein; n=1; ... 38 0.21 UniRef50_A2R0W5 Cluster: Remark: also show homology to different... 38 0.21 UniRef50_UPI0000D573E5 Cluster: PREDICTED: hypothetical protein;... 38 0.28 UniRef50_UPI0000ECB04E Cluster: Estradiol 17-beta-dehydrogenase ... 38 0.28 UniRef50_Q815Q8 Cluster: Short chain dehydrogenase; n=1; Bacillu... 38 0.28 UniRef50_Q140J4 Cluster: Putative 3-oxoacyl-(Acyl-carrier protei... 38 0.28 UniRef50_A5V6W3 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.28 UniRef50_Q7XIR1 Cluster: Carbonyl reductase-like protein; n=5; M... 38 0.28 UniRef50_A7RNF1 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.28 UniRef50_A2TIR8 Cluster: Receptor for egg jelly protein 9; n=9; ... 38 0.28 UniRef50_A2R494 Cluster: Contig An14c0200, complete genome; n=1;... 38 0.28 UniRef50_A3H6D0 Cluster: Short-chain dehydrogenase/reductase SDR... 38 0.28 UniRef50_A3J2Q4 Cluster: Short-chain dehydrogenase; n=2; Flavoba... 37 0.37 UniRef50_A2BY70 Cluster: Short-chain dehydrogenase/reductase (SD... 37 0.37 UniRef50_A1BFG5 Cluster: Short-chain dehydrogenase/reductase SDR... 37 0.37 UniRef50_A0Z5P1 Cluster: Short-chain dehydrogenase/reductase SDR... 37 0.37 UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte... 37 0.37 UniRef50_Q9XVS9 Cluster: Putative uncharacterized protein dhs-22... 37 0.37 UniRef50_Q4QHL1 Cluster: Dehydrogenase-like protein; n=3; Leishm... 37 0.37 UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methano... 37 0.37 UniRef50_P50162 Cluster: Tropinone reductase 1; n=77; Viridiplan... 37 0.37 UniRef50_UPI000023F261 Cluster: hypothetical protein FG04592.1; ... 37 0.49 UniRef50_Q2YCW1 Cluster: Short-chain dehydrogenase/reductase SDR... 37 0.49 UniRef50_Q9RBP5 Cluster: 1-hydroxy-2-glutathionyl-2-methyl-3-but... 37 0.49 UniRef50_A1TDV9 Cluster: Short-chain dehydrogenase/reductase SDR... 37 0.49 UniRef50_P37059 Cluster: Estradiol 17-beta-dehydrogenase 2; n=16... 37 0.49 UniRef50_UPI000155BF31 Cluster: PREDICTED: similar to double sub... 36 0.65 UniRef50_UPI000069F00A Cluster: Estradiol 17-beta-dehydrogenase ... 36 0.65 UniRef50_Q8F0Y4 Cluster: Sensor protein; n=3; Leptospira|Rep: Se... 36 0.65 UniRef50_Q7VAC7 Cluster: Light dependent protochlorophyllide oxi... 36 0.65 UniRef50_Q7D3F2 Cluster: AGR_pAT_417p; n=5; Alphaproteobacteria|... 36 0.65 UniRef50_A6GH96 Cluster: Putative short-chain dehydrogenase/redu... 36 0.65 UniRef50_A6CW76 Cluster: Putative short chain dehydrogenase; n=1... 36 0.65 UniRef50_A1ETE0 Cluster: Inner membrane transport protein YdhC; ... 36 0.65 UniRef50_A0B1Z9 Cluster: Short-chain dehydrogenase/reductase SDR... 36 0.65 UniRef50_A6SEL1 Cluster: Putative uncharacterized protein; n=2; ... 36 0.65 UniRef50_Q8NBN7 Cluster: Retinol dehydrogenase 13; n=19; Deutero... 36 0.65 UniRef50_Q89AG9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 36 0.65 UniRef50_UPI000023F4AA Cluster: hypothetical protein FG10334.1; ... 36 0.86 UniRef50_Q73NW4 Cluster: Conserved domain protein; n=1; Treponem... 36 0.86 UniRef50_Q0S4U3 Cluster: Dehydrogenase; n=2; Actinomycetales|Rep... 36 0.86 UniRef50_A0R7C5 Cluster: Oxidoreductase; n=3; Mycobacterium smeg... 36 0.86 UniRef50_Q109A3 Cluster: Oxidoreductase, short chain dehydrogena... 36 0.86 UniRef50_Q0CAF8 Cluster: Putative uncharacterized protein; n=1; ... 36 0.86 UniRef50_P40580 Cluster: Uncharacterized oxidoreductase YIR036C;... 36 0.86 UniRef50_UPI000023E6D6 Cluster: hypothetical protein FG03303.1; ... 36 1.1 UniRef50_Q4S4S9 Cluster: Chromosome 2 SCAF14738, whole genome sh... 36 1.1 UniRef50_Q986V1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 36 1.1 UniRef50_Q93HB3 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 36 1.1 UniRef50_Q8EUE2 Cluster: Short-chain alcohol dehydrogenase famil... 36 1.1 UniRef50_Q64PT9 Cluster: Putative oxidoreductase; n=7; Bacteroid... 36 1.1 UniRef50_Q0R4G2 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 36 1.1 UniRef50_A6UZF9 Cluster: Oxidoreductase, short chain dehydrogena... 36 1.1 UniRef50_A4T8M7 Cluster: Short-chain dehydrogenase/reductase SDR... 36 1.1 UniRef50_A3U149 Cluster: Short chain dehydrogenase; n=2; Proteob... 36 1.1 UniRef50_Q3LWJ0 Cluster: Putative uncharacterized protein; n=1; ... 36 1.1 UniRef50_O16625 Cluster: Signal element on autosome protein 2; n... 36 1.1 UniRef50_Q5QP22 Cluster: RNA binding motif protein 39; n=20; Coe... 36 1.1 UniRef50_Q0V5R8 Cluster: Putative uncharacterized protein; n=1; ... 36 1.1 UniRef50_Q0UC34 Cluster: Putative uncharacterized protein; n=1; ... 36 1.1 UniRef50_O05730 Cluster: Probable short-chain type dehydrogenase... 36 1.1 UniRef50_Q14498 Cluster: RNA-binding protein 39; n=55; Euteleost... 36 1.1 UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative a... 35 1.5 UniRef50_UPI0000E0FECB Cluster: putative short-chain dehydrogena... 35 1.5 UniRef50_Q6LLA8 Cluster: Putative uncharacterized protein MT0455... 35 1.5 UniRef50_Q30PF1 Cluster: Short-chain dehydrogenase/reductase SDR... 35 1.5 UniRef50_Q2IK95 Cluster: Short-chain dehydrogenase/reductase SDR... 35 1.5 UniRef50_Q1VWP8 Cluster: Short-chain dehydrogenase/reductase SDR... 35 1.5 UniRef50_Q03U43 Cluster: Short-chain alcohol dehydrogenase; n=4;... 35 1.5 UniRef50_A7HAP1 Cluster: Short-chain dehydrogenase/reductase SDR... 35 1.5 UniRef50_A4CMC6 Cluster: Putative uncharacterized protein; n=1; ... 35 1.5 UniRef50_Q9T0D9 Cluster: Putative uncharacterized protein AT4g11... 35 1.5 UniRef50_Q8RWK2 Cluster: Ribitol dehydrogenase-like; n=13; Magno... 35 1.5 UniRef50_Q7XCH4 Cluster: NAD dependent epimerase/dehydratase fam... 35 1.5 UniRef50_Q1AP31 Cluster: HAP2; n=7; Magnoliophyta|Rep: HAP2 - Ar... 35 1.5 UniRef50_Q4WGG7 Cluster: 3-ketoacyl-acyl carrier protein reducta... 35 1.5 UniRef50_Q0C8N8 Cluster: Predicted protein; n=2; Trichocomaceae|... 35 1.5 UniRef50_A2VEC7 Cluster: Chitinase 18-18; n=1; Hypocrea jecorina... 35 1.5 UniRef50_UPI0000E23758 Cluster: PREDICTED: similar to KIAA0853 p... 35 2.0 UniRef50_Q8YVT0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 35 2.0 UniRef50_Q399X9 Cluster: Short-chain dehydrogenase/reductase SDR... 35 2.0 UniRef50_A6W3U8 Cluster: Short-chain dehydrogenase/reductase SDR... 35 2.0 UniRef50_A6Q6X0 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 35 2.0 UniRef50_A6E753 Cluster: Probable dehydrogenase/reductase; n=1; ... 35 2.0 UniRef50_A4U033 Cluster: Spermidine/putrescine ABC transporter, ... 35 2.0 UniRef50_A1ZQT0 Cluster: Dehydrogenase/ reductase 1; n=1; Micros... 35 2.0 UniRef50_A1FWV1 Cluster: Short-chain dehydrogenase/reductase SDR... 35 2.0 UniRef50_A7P8T9 Cluster: Chromosome chr3 scaffold_8, whole genom... 35 2.0 UniRef50_A7EX22 Cluster: Putative uncharacterized protein; n=1; ... 35 2.0 UniRef50_A4RF90 Cluster: Putative uncharacterized protein; n=1; ... 35 2.0 UniRef50_Q5T200 Cluster: Zinc finger CCCH domain-containing prot... 35 2.0 UniRef50_Q07530 Cluster: Uncharacterized oxidoreductase YDL114W;... 35 2.0 UniRef50_O18404 Cluster: 3-hydroxyacyl-CoA dehydrogenase type-2;... 35 2.0 UniRef50_UPI0000E4927A Cluster: PREDICTED: similar to retinol de... 34 2.6 UniRef50_UPI0000499D20 Cluster: Sec7 domain protein; n=1; Entamo... 34 2.6 UniRef50_Q6NY49 Cluster: LOC407663 protein; n=23; Eumetazoa|Rep:... 34 2.6 UniRef50_P71947 Cluster: POSSIBLE phiRv2 PROPHAGE PROTEIN; n=13;... 34 2.6 UniRef50_Q6I0P1 Cluster: Putative uncharacterized protein; n=13;... 34 2.6 UniRef50_A6DIY7 Cluster: Probable large, multifunctional secrete... 34 2.6 UniRef50_A4EAZ8 Cluster: Putative uncharacterized protein; n=1; ... 34 2.6 UniRef50_A4AEV0 Cluster: Short chain dehydrogenase; n=1; marine ... 34 2.6 UniRef50_A3Y8D3 Cluster: Short chain dehydrogenase; n=1; Marinom... 34 2.6 UniRef50_A0YGX3 Cluster: Putative 3-oxoacyl-[ACP] reductase; n=1... 34 2.6 UniRef50_A0U1P6 Cluster: 200 kDa antigen p200, putative; n=3; Bu... 34 2.6 UniRef50_Q9W2N8 Cluster: CG10543-PA, isoform A; n=5; Drosophila ... 34 2.6 UniRef50_Q8I2Y8 Cluster: Putative uncharacterized protein PFI080... 34 2.6 UniRef50_Q6XPZ7 Cluster: Short-chain dehydrogenase/reductase; n=... 34 2.6 UniRef50_A2E7A2 Cluster: Putative uncharacterized protein; n=1; ... 34 2.6 UniRef50_Q55K76 Cluster: Putative uncharacterized protein; n=2; ... 34 2.6 UniRef50_Q2UTZ6 Cluster: Dehydrogenases with different specifici... 34 2.6 UniRef50_Q0UM96 Cluster: Putative uncharacterized protein; n=1; ... 34 2.6 UniRef50_A1CBV3 Cluster: Short chain dehydrogenase/reductase, pu... 34 2.6 UniRef50_Q5V473 Cluster: Short-chain dehydrogenase/oxidoreductas... 34 2.6 UniRef50_Q3IRP1 Cluster: Probable dehydrogenase/ reductase 11; n... 34 2.6 UniRef50_Q08651 Cluster: Uncharacterized oxidoreductase YOR246C;... 34 2.6 UniRef50_Q6P0H9 Cluster: Hydroxysteroid 11-beta dehydrogenase 2;... 34 3.5 UniRef50_Q9HYR5 Cluster: Probable short chain dehydrogenase; n=4... 34 3.5 UniRef50_Q98N12 Cluster: Probable oxidoreductase; n=1; Mesorhizo... 34 3.5 UniRef50_Q89ML0 Cluster: Blr4183 protein; n=16; Bacteria|Rep: Bl... 34 3.5 UniRef50_Q4FMU6 Cluster: Short chain dehydrogenase; n=3; Bacteri... 34 3.5 UniRef50_Q1AY52 Cluster: Short-chain dehydrogenase/reductase SDR... 34 3.5 UniRef50_A5PEG3 Cluster: Putative uncharacterized protein; n=1; ... 34 3.5 UniRef50_A7PZ82 Cluster: Chromosome chr15 scaffold_40, whole gen... 34 3.5 UniRef50_Q9W0B0 Cluster: CG7971-PC, isoform C; n=7; Endopterygot... 34 3.5 UniRef50_A7SMN3 Cluster: Predicted protein; n=1; Nematostella ve... 34 3.5 UniRef50_Q5VTL8 Cluster: Pre-mRNA-splicing factor 38B; n=30; Bil... 34 3.5 UniRef50_P37694 Cluster: Ketoacyl reductase hetN; n=3; Nostocace... 34 3.5 UniRef50_UPI000155BD1D Cluster: PREDICTED: hypothetical protein,... 33 4.6 UniRef50_Q97J50 Cluster: Putative uncharacterized protein CAC143... 33 4.6 UniRef50_Q92SJ2 Cluster: Sensor protein; n=2; Sinorhizobium|Rep:... 33 4.6 UniRef50_Q8R940 Cluster: Dehydrogenases with different specifici... 33 4.6 UniRef50_Q7MJD1 Cluster: Methyl-accepting chemotaxis protein; n=... 33 4.6 UniRef50_Q9WWC0 Cluster: AtsC; n=3; Agrobacterium tumefaciens|Re... 33 4.6 UniRef50_Q0VMN8 Cluster: Dehydrogenase/reductase; n=1; Alcanivor... 33 4.6 UniRef50_O84991 Cluster: Putative short-chain dehydrogenase/redu... 33 4.6 UniRef50_A3ZTM1 Cluster: Probable short-chain dehydrogenase; n=1... 33 4.6 UniRef50_A1GDI9 Cluster: Putative uncharacterized protein; n=1; ... 33 4.6 UniRef50_A1G986 Cluster: Short-chain dehydrogenase/reductase SDR... 33 4.6 UniRef50_A0M2N9 Cluster: Short-chain dehydrogenase/reductase fam... 33 4.6 UniRef50_A0JWV5 Cluster: Short-chain dehydrogenase/reductase SDR... 33 4.6 UniRef50_Q9LFS7 Cluster: Putative uncharacterized protein F1N13_... 33 4.6 UniRef50_Q8IM21 Cluster: Putative uncharacterized protein; n=2; ... 33 4.6 UniRef50_Q5DEA2 Cluster: SJCHGC03296 protein; n=1; Schistosoma j... 33 4.6 UniRef50_Q4QAE9 Cluster: Short chain dehydrogenase/reductase, pu... 33 4.6 UniRef50_Q2TW48 Cluster: Dehydrogenases with different specifici... 33 4.6 UniRef50_A3LNQ0 Cluster: Short-chain alcohol dehydrogenase retin... 33 4.6 UniRef50_Q2FST7 Cluster: Putative PAS/PAC sensor protein precurs... 33 4.6 UniRef50_A7DRK3 Cluster: Glucose sorbosone dehydrogenase precurs... 33 4.6 UniRef50_UPI00015B4F48 Cluster: PREDICTED: similar to ENSANGP000... 33 6.1 UniRef50_UPI0000E49E46 Cluster: PREDICTED: similar to Retinol de... 33 6.1 UniRef50_UPI000023E82F Cluster: hypothetical protein FG01599.1; ... 33 6.1 UniRef50_Q801X5 Cluster: 11beta hydroxysteroid dehydrogenase; n=... 33 6.1 UniRef50_Q4S435 Cluster: Chromosome 20 SCAF14744, whole genome s... 33 6.1 UniRef50_A1L3J0 Cluster: LOC100037020 protein; n=6; Euteleostomi... 33 6.1 UniRef50_Q4ZND0 Cluster: Erythronolide synthase; n=1; Pseudomona... 33 6.1 UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR... 33 6.1 UniRef50_Q48154 Cluster: Bifunctional Ribulose 5-phosphate reduc... 33 6.1 UniRef50_Q26CE0 Cluster: Putative oxidoreductase-dehydrogenase; ... 33 6.1 UniRef50_A7LYE0 Cluster: Putative uncharacterized protein; n=1; ... 33 6.1 UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR... 33 6.1 UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR... 33 6.1 UniRef50_A2Z059 Cluster: Putative uncharacterized protein; n=1; ... 33 6.1 UniRef50_Q5KSV0 Cluster: GATA zinc finger protein; n=2; Dictyost... 33 6.1 UniRef50_Q23BV3 Cluster: Putative uncharacterized protein; n=1; ... 33 6.1 UniRef50_A0DTM3 Cluster: Chromosome undetermined scaffold_63, wh... 33 6.1 UniRef50_Q4PBC6 Cluster: Putative uncharacterized protein; n=1; ... 33 6.1 UniRef50_Q2HD97 Cluster: Putative uncharacterized protein; n=1; ... 33 6.1 UniRef50_Q0U9T1 Cluster: Predicted protein; n=1; Phaeosphaeria n... 33 6.1 UniRef50_Q05330 Cluster: D2145 protein; n=1; Saccharomyces cerev... 33 6.1 UniRef50_A3LUB3 Cluster: Predicted protein; n=6; Saccharomycetal... 33 6.1 UniRef50_A3LNP9 Cluster: Short-chain alcohol dehydrogenase; n=1;... 33 6.1 UniRef50_A2QR41 Cluster: Contig An08c0130, complete genome; n=1;... 33 6.1 UniRef50_P09799 Cluster: Vicilin GC72-A precursor; n=28; Malvace... 33 6.1 UniRef50_Q9VHA0 Cluster: Polycomb protein Scm; n=6; Coelomata|Re... 33 6.1 UniRef50_UPI00015B50B6 Cluster: PREDICTED: similar to trichohyal... 33 8.0 UniRef50_UPI000058674C Cluster: PREDICTED: similar to Smad nucle... 33 8.0 UniRef50_UPI000049978B Cluster: short chain dehydrogenase family... 33 8.0 UniRef50_Q4SN30 Cluster: Chromosome 6 SCAF14544, whole genome sh... 33 8.0 UniRef50_Q72N35 Cluster: Short-chain dehydrogenase; n=7; Bacteri... 33 8.0 UniRef50_Q1VJ65 Cluster: Polynucleotide adenylyl transferase; n=... 33 8.0 UniRef50_Q0SFE0 Cluster: Probable short chain dehydrogenase; n=1... 33 8.0 UniRef50_Q096Q5 Cluster: Putative uncharacterized protein; n=1; ... 33 8.0 UniRef50_A6F000 Cluster: Putative short-chain dehydrogenase/redu... 33 8.0 UniRef50_A6EIS2 Cluster: Probable dehydrogenase/reductase; n=1; ... 33 8.0 UniRef50_A3U7Y8 Cluster: Oxidoreductase; n=2; Flavobacteriaceae|... 33 8.0 UniRef50_A1ZFM2 Cluster: Oxidoreductase; n=1; Microscilla marina... 33 8.0 UniRef50_A1ETD9 Cluster: Putative uncharacterized protein; n=1; ... 33 8.0 UniRef50_A0KVV1 Cluster: Short-chain dehydrogenase/reductase SDR... 33 8.0 UniRef50_Q3EBS2 Cluster: Uncharacterized protein At2g29340.1; n=... 33 8.0 UniRef50_Q9GV73 Cluster: HNF-3; n=1; Halocynthia roretzi|Rep: HN... 33 8.0 UniRef50_Q622F1 Cluster: Putative uncharacterized protein CBG022... 33 8.0 UniRef50_Q54I93 Cluster: Putative uncharacterized protein; n=1; ... 33 8.0 UniRef50_Q54I21 Cluster: Putative uncharacterized protein; n=1; ... 33 8.0 UniRef50_Q38A58 Cluster: Putative uncharacterized protein; n=1; ... 33 8.0 UniRef50_Q22KE2 Cluster: Putative uncharacterized protein; n=1; ... 33 8.0 UniRef50_A2E6G2 Cluster: Putative uncharacterized protein; n=1; ... 33 8.0 UniRef50_A0D4D6 Cluster: Chromosome undetermined scaffold_37, wh... 33 8.0 UniRef50_Q5AEE8 Cluster: Putative uncharacterized protein RSD1; ... 33 8.0 UniRef50_A6RJU0 Cluster: Putative uncharacterized protein; n=1; ... 33 8.0 >UniRef50_A7RGK5 Cluster: Predicted protein; n=4; Eumetazoa|Rep: Predicted protein - Nematostella vectensis Length = 275 Score = 123 bits (296), Expect = 4e-27 Identities = 68/205 (33%), Positives = 116/205 (56%), Gaps = 2/205 (0%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VA+V G+ +G+ +++ L + G + T ++ G + L+ + + Q+DIT Sbjct: 8 VAVVTGSNKGIGFAIVRGLCKQFSGTVILTARNENLGKEAVDKLKEEGLNPVFHQLDITS 67 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAE-KNLSNF-EKIRRTLSVNFYGYINFGKLVY 371 +SI +LR Y+ + +DLLIN + +++ F E+ T NF G +N ++ Sbjct: 68 QESINKLRDYLSSTYKGLDLLINNAGIAYKGASIAPFSEQAEVTARTNFTGTLNICDTLF 127 Query: 372 PLLNENARVVNVSGPAGLLATIENEDIRKRISDPTLTEDELVALIQEYEHAARRGVEKTE 551 PLL +ARVVNV+ AGLL I +E I+ + + P+LT+ LV L++E+ + GV K + Sbjct: 128 PLLRPHARVVNVASLAGLLKIIPSEAIKAKFTSPSLTQSGLVGLVEEFISDVKAGVHKEK 187 Query: 552 GWGMNVHAVSKVALNAVTFLQHRGM 626 GW + + +SKVA+ A+T +Q R M Sbjct: 188 GWSNSAYGMSKVAVIALTKVQARQM 212 >UniRef50_O97166 Cluster: 3-alpha-hydroxysteroid dehydrogenase-like protein; n=1; Branchiostoma floridae|Rep: 3-alpha-hydroxysteroid dehydrogenase-like protein - Branchiostoma floridae (Florida lancelet) (Amphioxus) Length = 273 Score = 111 bits (268), Expect = 1e-23 Identities = 62/208 (29%), Positives = 109/208 (52%), Gaps = 4/208 (1%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMD 188 M VA+V GA +G ++K L + G +Y T D++ G +K L + + Q+D Sbjct: 1 MSRVAVVTGANKGIGLAIVKGLCKQFDGTVYLTARDESKGQEAVKELNEQGCQPRFHQLD 60 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITD--YVAEKNLSNFEKIRRTLSVNFYGYINFGK 362 + SI R + +++ + +D+L+N Y E++ T+ +NF+G +N K Sbjct: 61 VLSLDSIHRFKQHLEKEHQGLDVLVNNAGVMYGGSNPTPLVEQVEVTMGINFFGLLNLTK 120 Query: 363 LVYPLLNENARVVNVSGPAGLLATIENEDIRKRISDPTLTEDELVALIQEYEHAARRGVE 542 + PLL +AR+VNVS G L+ + E R+ LTE+ELV +++++ + GV Sbjct: 121 ALTPLLKPHARIVNVSSGLGDLSYVTPER-RQTFQSKQLTEEELVQMMEQFVRDVKSGVH 179 Query: 543 KTEGWGMNV--HAVSKVALNAVTFLQHR 620 + +GW M + VSK+ A++ +Q R Sbjct: 180 EEKGWKMEPLGYRVSKMGATALSMVQQR 207 >UniRef50_P16152 Cluster: Carbonyl reductase [NADPH] 1 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase 1) (Prostaglandin-E(2) 9-reductase); n=74; Euteleostomi|Rep: Carbonyl reductase [NADPH] 1 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase 1) (Prostaglandin-E(2) 9-reductase) - Homo sapiens (Human) Length = 277 Score = 88.2 bits (209), Expect = 2e-16 Identities = 54/206 (26%), Positives = 104/206 (50%), Gaps = 4/206 (1%) Frame = +3 Query: 15 NVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDIT 194 +VALV G +G +++ L G + T D T G ++ L+ + + Q+DI Sbjct: 6 HVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDID 65 Query: 195 YTKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 365 +SI LR +++ +D+L+N I VA+ + + T+ NF+G + Sbjct: 66 DLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQ-AEVTMKTNFFGTRDVCTE 124 Query: 366 VYPLLNENARVVNVSGPAGLLATIE-NEDIRKRISDPTLTEDELVALIQEYEHAARRGVE 542 + PL+ RVVNVS + A + +++++ T+TE+ELV L+ ++ ++GV Sbjct: 125 LLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVH 184 Query: 543 KTEGWGMNVHAVSKVALNAVTFLQHR 620 + EGW + + V+K+ + ++ + R Sbjct: 185 QKEGWPSSAYGVTKIGVTVLSRIHAR 210 >UniRef50_A7SF98 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 263 Score = 83.0 bits (196), Expect = 6e-15 Identities = 60/207 (28%), Positives = 98/207 (47%), Gaps = 9/207 (4%) Frame = +3 Query: 27 VVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTKS 206 V G +GY V+++L + G I T D G +SL + Y ++D+T S Sbjct: 1 VTGGNRGIGYCVVQQLVQQFDGNIILTARSDEQGEAACRSLNVGG-RVEYHKLDVTSNDS 59 Query: 207 IIRLRHYIQDLDERIDLLINITDYVAEKN--LSNFEKIRRTLSVNFYGYINFGKLVYPLL 380 I L ++Q+ +D+L+N + +++ S K + NF+G ++ +YPLL Sbjct: 60 IHELTLHVQEKYGGLDILVNNAGILKKESSGTSYARKAEDCVKTNFFGMLDVYNSMYPLL 119 Query: 381 NENARVVNVSGPAGLLATIENEDIRKRISDPTLTEDELVALIQEYEHAARRGVEKTEGW- 557 E AR+VNVS G L I + + + P LT + V L+Q Y + G GW Sbjct: 120 KEQARIVNVSSTMGSL-KIVHPSLALQFISPKLTVRQCVNLMQAYIRDVKNGRVAENGWP 178 Query: 558 --GMNVH----AVSKVALNAVTFLQHR 620 + VH +VSK+ + A+T + R Sbjct: 179 VEKLKVHNPAYSVSKLGVTALTSILAR 205 >UniRef50_A0E1K9 Cluster: Chromosome undetermined scaffold_73, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_73, whole genome shotgun sequence - Paramecium tetraurelia Length = 276 Score = 83.0 bits (196), Expect = 6e-15 Identities = 47/198 (23%), Positives = 98/198 (49%), Gaps = 7/198 (3%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTED-DTAGFNILKSLERPDIE---ISYLQMDI 191 ++ GA +G+ +L+ L + K+ + A + + +E+ ++ I +++DI Sbjct: 8 VITGANKGIGFGILENLIQKQSYKVIMACRSLELAQKSRTELIEKYNLSQDRIDIIELDI 67 Query: 192 TYTKSIIRLRHYIQDLDERI---DLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGK 362 + + SI + +IQ+ R D+LIN + + NFE ++ T NFYG + + Sbjct: 68 SSSDSIDK---FIQEFTTRFHSADILINNAAVAVKTDDFNFEIVQYTFKPNFYGTVELTE 124 Query: 363 LVYPLLNENARVVNVSGPAGLLATIENEDIRKRISDPTLTEDELVALIQEYEHAARRGVE 542 PLL +N +++ + G +E++D+ KR +P +T +++ L E++ + Sbjct: 125 KFIPLLAQNGKIITIGSQVGNTKILESDDLVKRFKNPNITREDVFKLADEFQEHVKNNTY 184 Query: 543 KTEGWGMNVHAVSKVALN 596 K GW + +SK+ +N Sbjct: 185 KQNGWPSWGYGISKLLIN 202 >UniRef50_UPI0000E498BD Cluster: PREDICTED: similar to Carbonyl reductase 1; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Carbonyl reductase 1 - Strongylocentrotus purpuratus Length = 291 Score = 82.2 bits (194), Expect = 1e-14 Identities = 47/202 (23%), Positives = 104/202 (51%), Gaps = 3/202 (1%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTET--HKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDI 191 VA+V G+ + +G +++ L + G +Y T ++ G ++ L++ + + +D+ Sbjct: 5 VAVVTGSNTGIGLAMVRALCKHFGENGVVYLTARNEERGMQAVEVLKKEGLNPRFHLLDV 64 Query: 192 TYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 371 S+ +LR I+ +D+LIN +++ ++ +E+ + N++G + Sbjct: 65 NDVTSMEKLRDDIKTEHGGVDILINNAGILSKFDIPMYEQAVEMTNTNYHGVLLMTNTFL 124 Query: 372 PLLNENARVVNVSGPAGLLATIE-NEDIRKRISDPTLTEDELVALIQEYEHAARRGVEKT 548 P++ + RVV ++ G + +E+++ R D + T +E+ L+ EY A + G KT Sbjct: 125 PIIRDGGRVVQLASLMGARTFYDISEELQHRFRDVS-TVEEVTGLMNEYIKATKEGDFKT 183 Query: 549 EGWGMNVHAVSKVALNAVTFLQ 614 +GW + +SK+ + A+T +Q Sbjct: 184 KGWAELAYGISKIGVAALTKVQ 205 >UniRef50_Q5DEH8 Cluster: SJCHGC00683 protein; n=2; Schistosoma|Rep: SJCHGC00683 protein - Schistosoma japonicum (Blood fluke) Length = 277 Score = 80.6 bits (190), Expect = 3e-14 Identities = 60/207 (28%), Positives = 98/207 (47%), Gaps = 9/207 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETH----KGKIYFTTEDDTAGFNILKSLERPDIEISYLQM 185 +A V G+ +GY +++KL E + + IY T + G +K L +++ + Q+ Sbjct: 3 LAFVTGSNKGIGYNIVEKLAEFYGESSEWDIYLTARNVELGLEAVKKLSGKGLDVKFHQL 62 Query: 186 DITYTKSIIRLRHYIQ-DLDERIDLLINITD--YVAEKNLSNFEKIRRTLSVNFYGYINF 356 DIT S +++ + I++ +N Y E E+ R T++ NF I+F Sbjct: 63 DITDRDSRKAFLTFVKTNYPNGINVAVNNAGIAYKVESATPFGEQARVTINTNFTSTIDF 122 Query: 357 GKLVYPLLNENARVVNVSGPAGL--LATIENEDIRKRISDPTLTEDELVALIQEYEHAAR 530 + PLL E+ARVVNVS L L + N+ K + L EL L+ E+ AA Sbjct: 123 TEEFIPLLAEHARVVNVSSSLSLTSLKNLRNDLYEKFVGPMNLI--ELRKLMSEFVKAAE 180 Query: 531 RGVEKTEGWGMNVHAVSKVALNAVTFL 611 G +GW + VSK+ L +F+ Sbjct: 181 DGTCSEKGWPSTAYEVSKLGLTKASFI 207 >UniRef50_Q501A2 Cluster: At5g61830; n=8; Magnoliophyta|Rep: At5g61830 - Arabidopsis thaliana (Mouse-ear cress) Length = 316 Score = 77.0 bits (181), Expect = 4e-13 Identities = 56/212 (26%), Positives = 106/212 (50%), Gaps = 13/212 (6%) Frame = +3 Query: 15 NVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPD--IEISYLQMD 188 NVA+V G+ +G+++ ++L H + T + AG +KSL + +++ + Q+D Sbjct: 37 NVAVVTGSNRGIGFEIARQLA-VHGLTVVLTARNVNAGLEAVKSLRHQEEGLKVYFHQLD 95 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRT-LSVNFYGYINFGKL 365 +T + SI +++ +D+L+N N + T +S N+ G N K Sbjct: 96 VTDSSSIREFGCWLKQTFGGLDILVNNAGVNYNLGSDNTVEFAETVISTNYQGTKNMTKA 155 Query: 366 VYPLLN---ENARVVNVSGPAGLL----ATIENEDIRKRISDPTLTEDELV-ALIQEYEH 521 + PL+ ARVVNVS G + + N ++R ++S P L +EL+ + ++ + Sbjct: 156 MIPLMRPSPHGARVVNVSSRLGRVNGRRNRLANVELRDQLSSPDLLTEELIDRTVSKFIN 215 Query: 522 AARRGVEKTEGWGMNV--HAVSKVALNAVTFL 611 + G ++ GW +++SK+A+NA T L Sbjct: 216 QVKDGTWESGGWPQTFTDYSMSKLAVNAYTRL 247 >UniRef50_Q22DT5 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=3; Oligohymenophorea|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Tetrahymena thermophila SB210 Length = 282 Score = 76.6 bits (180), Expect = 5e-13 Identities = 45/193 (23%), Positives = 94/193 (48%), Gaps = 2/193 (1%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLE-RPDIEISYLQMDITYT 200 +V G+ +GY +++ L I + A + K L+ P +I ++DI T Sbjct: 16 IVTGSNKGVGYGIIENLAAKPYHIIMACRSLERANESRSKLLQIHPHAKIDSYELDIDST 75 Query: 201 KSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPLL 380 SI + I +D+L+N + + + + + +T NFYG I+ + + P + Sbjct: 76 DSINKFVQQIHQHYGYVDILLNNSGMAFKGDAFGADVVEQTFRTNFYGTIDLTEKMLPYI 135 Query: 381 NENARVVNVSGPAGLLATIE-NEDIRKRISDPTLTEDELVALIQEYEHAARRGVEKTEGW 557 EN +V+ V AG ++ N+ + +++ +P LT+D+L A+ +++ + +GW Sbjct: 136 KENGKVIFVGSSAGKYHNVKNNQAVLQQLQNPHLTKDQLFAVAKQFYDDVKDDTYAQKGW 195 Query: 558 GMNVHAVSKVALN 596 + + +SK+ +N Sbjct: 196 AKSAYGMSKLCIN 208 >UniRef50_UPI0000E494E7 Cluster: PREDICTED: similar to Carbonyl reductase 1; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Carbonyl reductase 1 - Strongylocentrotus purpuratus Length = 417 Score = 74.5 bits (175), Expect = 2e-12 Identities = 47/200 (23%), Positives = 92/200 (46%), Gaps = 4/200 (2%) Frame = +3 Query: 27 VVGAASNLGYQVLKKLTET--HKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYT 200 V GA +G ++++ L G +Y T + G ++ L++ ++ + +D+T Sbjct: 17 VTGANKGIGLEIVRALCRHFGQDGVVYLTARNIGRGRAAVELLQKEGLDPKFHLLDVTDQ 76 Query: 201 KSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPLL 380 SI + R +++ ID+L+N + + K + NF+G + + + PL+ Sbjct: 77 SSIDKFRDHLEKEHGGIDVLVNNAGIGTPNHFPLYGKSLWVMKTNFFGVLAISQSLIPLV 136 Query: 381 NENARVVNVSGPAGLLATIE--NEDIRKRISDPTLTEDELVALIQEYEHAARRGVEKTEG 554 R+V+V+G G + N+DIR R E ++V LI E+ + G G Sbjct: 137 RSGGRIVHVAGTTGYMVFRNQFNDDIRNRFR-KAKDEQDVVDLINEFLKFCKEGTIAENG 195 Query: 555 WGMNVHAVSKVALNAVTFLQ 614 W ++KV + A++ +Q Sbjct: 196 WPDEADGIAKVGVIALSKIQ 215 >UniRef50_UPI0000E46681 Cluster: PREDICTED: similar to carbonyl reductase; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to carbonyl reductase - Strongylocentrotus purpuratus Length = 312 Score = 74.5 bits (175), Expect = 2e-12 Identities = 54/223 (24%), Positives = 106/223 (47%), Gaps = 24/223 (10%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTET--HKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDI 191 VA+V GA +G ++++ L G +Y T ++ G ++ L++ ++ + +D+ Sbjct: 5 VAVVTGANKGIGLEIVRALCRHFGQDGVVYLTARNEGRGLAAIELLQKEGLDPKFHLLDV 64 Query: 192 TYTKSIIRLRHYIQDLDERIDLLIN-------------------ITDYVAEK-NLSNFEK 311 T SI ++R++++ ID+L+N T+ V +K N+S +EK Sbjct: 65 TDQSSIEKIRNHLEKEHGGIDVLVNNAGIDTPDGEIYAGLDLVIFTNLVLQKENISFYEK 124 Query: 312 IRRTLSVNFYGYINFGKLVYPLLNENARVVNVSGPAGLLATIE--NEDIRKRISDPTLTE 485 R + NF+G I+ + + PL+ R+VNV+ G + E ++IR R E Sbjct: 125 RFRVMEANFFGLISVCQSIIPLVRSGRRIVNVASTTGYIVFREQLTDEIRNRFRQ-VKDE 183 Query: 486 DELVALIQEYEHAARRGVEKTEGWGMNVHAVSKVALNAVTFLQ 614 ++V L+ E+ + GW + VSK+ + ++ +Q Sbjct: 184 QDVVDLMNEFLECCKTETNAANGWTTWSYGVSKLGVILLSKIQ 226 >UniRef50_Q01IF3 Cluster: H0306B06.2 protein; n=15; Magnoliophyta|Rep: H0306B06.2 protein - Oryza sativa (Rice) Length = 294 Score = 67.3 bits (157), Expect = 3e-10 Identities = 49/201 (24%), Positives = 94/201 (46%), Gaps = 7/201 (3%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VA+V GA +G + +L E H + T D G +L + + + ++D+ Sbjct: 21 VAVVTGANRGIGLALAARLGE-HGITVVLTARDAERGEAAAAALRARGLHVVFHRLDVAD 79 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDY-VAEKNLSNFEKIRRTLSVNFYGYINFGKLVYP 374 S+ +++D +D+L+N E + ++ E L NFYG + + P Sbjct: 80 PASVQAFAAWLRDAIGGLDILVNNAAVSFNEIDTNSVEHAETVLRTNFYGAKMLTEALLP 139 Query: 375 LLNEN---ARVVNVSGPAGLLATIENEDIRKRISD-PTLTEDELVALIQEYEHAARRGVE 542 L + +R++N+S GLL + + ++++ + D LTE E+ + + + G Sbjct: 140 LFRRSPATSRILNISSQLGLLNKVSDPELKRLLQDEERLTEAEVEGMASRFLAQVKDGTW 199 Query: 543 KTEGWG--MNVHAVSKVALNA 599 + +GW ++VSK+ALNA Sbjct: 200 RGQGWPKVWTDYSVSKLALNA 220 >UniRef50_Q233Z6 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=3; Tetrahymena thermophila SB210|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Tetrahymena thermophila SB210 Length = 285 Score = 66.9 bits (156), Expect = 4e-10 Identities = 47/216 (21%), Positives = 101/216 (46%), Gaps = 13/216 (6%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKG--KIYFTTEDDTAGFNILKSLER--PDIEISYLQM 185 V L+ G+ LG+ +++ + + ++ T D G + ++ P E+ + + Sbjct: 7 VVLITGSNKGLGFGLVEDILSKNSSQFRVIMTARDQLRGEEAFQKIKAKYPAEEVDFHLL 66 Query: 186 DITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSN--------FEKIRRTLSVNFY 341 DI +S I + YI + +ID+L+N Y+ +L N E +RT S+N + Sbjct: 67 DIEDEQSRINIVKYIAEKYGKIDILVNNAAYLLTHDLFNQPEGYQPSVETAKRTFSINLF 126 Query: 342 GYINFGKLVYPLLNENARVVNVSGPAGLLATIENEDIRKRISDPTLTEDELVALIQE-YE 518 G I+ + + P L ++ +++ +S AG ++ + + + + ++ L ++ Y+ Sbjct: 127 GTISMTQQIIPYLADDGKILQISSRAGQISRQPQQTQQILSNSEGFSVQKITELAEDFYK 186 Query: 519 HAARRGVEKTEGWGMNVHAVSKVALNAVTFLQHRGM 626 + + + W + + VSK LNA F +H G+ Sbjct: 187 QCENKIQPQDQRWSFSAYEVSKCLLNA--FTRHVGL 220 >UniRef50_Q097P7 Cluster: Carbonyl reductase [NADPH] 1 (Nadph-dependent carbonylreductase 1) (20-beta-hydroxysteroid dehydrogenase) (Prostaglandin-e(2) 9- reductase); n=2; Stigmatella aurantiaca DW4/3-1|Rep: Carbonyl reductase [NADPH] 1 (Nadph-dependent carbonylreductase 1) (20-beta-hydroxysteroid dehydrogenase) (Prostaglandin-e(2) 9- reductase) - Stigmatella aurantiaca DW4/3-1 Length = 234 Score = 65.3 bits (152), Expect = 1e-09 Identities = 43/160 (26%), Positives = 79/160 (49%), Gaps = 6/160 (3%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 +ALV GA LG ++ K+L ++ T + G ++L + +S+L +D+T Sbjct: 6 IALVTGANRGLGLELCKQLA-ARGTRVLLTARSEEKGQKAARALAEQGLPVSFLWLDVTS 64 Query: 198 TKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLS-NFEKIRRTLSVNFYGYINFGKL 365 +S+++ YI R+D+L+N ++ + L + +R T+ N YG + +L Sbjct: 65 EQSLVQGVEYISREFGRLDILVNNAAVSLDLKRPGLEIGMDIVRTTIETNVYGPLRLTQL 124 Query: 366 VYPLLNEN--ARVVNVSGPAGLLATIENEDIRKRISDPTL 479 PL+ +N R+VNVS G + I + R+S +L Sbjct: 125 AVPLMRKNHYGRIVNVSSGLGSFSRITAGKLAYRLSKASL 164 >UniRef50_Q6H7D1 Cluster: Short-chain dehydrogenase/reductase protein-like; n=2; Oryza sativa|Rep: Short-chain dehydrogenase/reductase protein-like - Oryza sativa subsp. japonica (Rice) Length = 324 Score = 48.0 bits (109), Expect(2) = 1e-09 Identities = 34/125 (27%), Positives = 63/125 (50%), Gaps = 5/125 (4%) Frame = +3 Query: 252 DLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPLL--NENARVVNVSGPAGL 425 DL+ + Y+ N+E + L +NFYG + + PLL + + +V+N++ Sbjct: 139 DLMGFLNSYMGSLQ-QNYEMAKECLEINFYGTKDVTDCLMPLLLLSNSGKVINLTSKISQ 197 Query: 426 LATIENEDIRKRISD-PTLTEDELVALIQEYEHAARRGVEKTEGWG--MNVHAVSKVALN 596 L I NE + K +SD L++++L + + + G + GW ++ +AVSK +N Sbjct: 198 LQFISNEGVIKVLSDIDNLSDEKLKDVASIFLKDFKDGNLEAHGWQPVVSAYAVSKTLVN 257 Query: 597 AVTFL 611 A + L Sbjct: 258 AYSRL 262 Score = 37.1 bits (82), Expect(2) = 1e-09 Identities = 21/84 (25%), Positives = 46/84 (54%), Gaps = 1/84 (1%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIE-ISYLQMDIT 194 VA+V G +G ++ ++L ++ + T D+ G +K+LE+ + + + Q+D+T Sbjct: 28 VAVVTGGNRGVGLEICRQLA-SNGILVVLTARDEKKGSQAVKALEQSGLSGVIFHQLDVT 86 Query: 195 YTKSIIRLRHYIQDLDERIDLLIN 266 SI+ L +I+ + ++L+N Sbjct: 87 DRSSIMLLVEFIRTKFGKFNILVN 110 >UniRef50_Q4L7K1 Cluster: Similar to 3(or 17)beta-hydroxysteroid dehydrogenase; n=1; Staphylococcus haemolyticus JCSC1435|Rep: Similar to 3(or 17)beta-hydroxysteroid dehydrogenase - Staphylococcus haemolyticus (strain JCSC1435) Length = 285 Score = 62.5 bits (145), Expect = 9e-09 Identities = 45/148 (30%), Positives = 74/148 (50%), Gaps = 5/148 (3%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKG-KIYFTTEDDTAGFNILKSLERPDIEISYLQMDIT 194 +ALV GA+S LG++ L E KG ++Y T + N+ + +++++ L++D+T Sbjct: 5 IALVTGASSGLGFETSLMLAE--KGFQVYATMRNLENQMNLKIEATKRNVDLTILELDVT 62 Query: 195 YTKSIIRLRHYIQDLDERIDLLINITDYVAEKNL--SNFEKIRRTLSVNFYGYINFGKLV 368 SI +I + RID+LIN K + E+I L++N G I K V Sbjct: 63 KLDSIKSAVEFIIQEEGRIDILINNAGAGFNKTTEQATDEEINWQLNLNLMGVIRMTKAV 122 Query: 369 YPLL--NENARVVNVSGPAGLLATIENE 446 P++ RV+N+S GL+ NE Sbjct: 123 LPIMRSQREGRVINISSVGGLVGQPFNE 150 >UniRef50_Q22BQ2 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=2; Tetrahymena thermophila SB210|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Tetrahymena thermophila SB210 Length = 274 Score = 60.5 bits (140), Expect = 4e-08 Identities = 52/203 (25%), Positives = 94/203 (46%), Gaps = 7/203 (3%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKI-YFTTEDDTAGFNILKSLE--RPDIEISYLQMD 188 +A++ GA LG + L + Y TE + ++L+ P+ + +D Sbjct: 5 IAILTGANRGLGRTTAEILVSKYANNFQYIFTERSKNHDELTQALKSINPNAQFEVKDLD 64 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITD-YVAEKNLS---NFEKIRRTLSVNFYGYINF 356 I+ +S + + +I +ID+L N Y +K+ N E TL++NF + F Sbjct: 65 ISSQESRAQFKQWISQKYHKIDVLFNNAGVYDKDKDTGARPNKETAEFTLNINFINTVEF 124 Query: 357 GKLVYPLLNENARVVNVSGPAGLLATIENEDIRKRISDPTLTEDELVALIQEYEHAARRG 536 + +YPL+ E+ ++V +S G L + E ++ + + LT+D+L L Y + A Sbjct: 125 TEELYPLVTEDGKIVVISSQLGKL-DHQPEAAKQLLVNENLTKDKLFELAHNYINNAGT- 182 Query: 537 VEKTEGWGMNVHAVSKVALNAVT 605 +K + V+ SK LNA T Sbjct: 183 PDKDLIFSNYVYFTSKALLNAYT 205 >UniRef50_Q00RH9 Cluster: OSIGBa0125M19.7 protein; n=12; Oryza sativa|Rep: OSIGBa0125M19.7 protein - Oryza sativa (Rice) Length = 1204 Score = 59.3 bits (137), Expect = 8e-08 Identities = 38/132 (28%), Positives = 70/132 (53%), Gaps = 6/132 (4%) Frame = +3 Query: 228 IQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPLL--NENARVV 401 ++D E +D+ + +++ E + +++ + ++ N+YG + + PLL + + R+V Sbjct: 781 VKDQIEGMDVDQRV-EWMRENSKETYDEAKSCITTNYYGAKLVTEALLPLLLLSSSGRIV 839 Query: 402 NVSGPAGLLATIENEDIRKRISD-PTLTEDELVALIQEYEHAARRGVEKTEGW---GMNV 569 NVS GLL +ED+RK D +LTE L L+ + + + + GW G + Sbjct: 840 NVSSGFGLLRNFNSEDLRKEFDDIDSLTEKRLEELLDLFLDDFKVNLIEAHGWPTGGSSA 899 Query: 570 HAVSKVALNAVT 605 + V+K ALNA T Sbjct: 900 YKVAKAALNAYT 911 Score = 42.7 bits (96), Expect = 0.008 Identities = 22/86 (25%), Positives = 44/86 (51%), Gaps = 3/86 (3%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERP---DIEISYLQMD 188 +ALV G +G + ++L ++ T ++ G + + R D ++ + Q+D Sbjct: 680 IALVTGGNKGVGLETCRQLASRGL-RVVLTARNEARGLEAVDGIRRSGAADSDVVFHQLD 738 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLIN 266 +T S+ RL +++D R+D+LIN Sbjct: 739 VTDAASVARLADFVRDQFGRLDILIN 764 >UniRef50_A4BA05 Cluster: Short chain dehydrogenase; n=1; Reinekea sp. MED297|Rep: Short chain dehydrogenase - Reinekea sp. MED297 Length = 302 Score = 58.8 bits (136), Expect = 1e-07 Identities = 46/177 (25%), Positives = 79/177 (44%), Gaps = 6/177 (3%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLER-PDIEISYLQMDIT 194 VA+V GA LG+ L + + D A I + + PD ++ ++ +D++ Sbjct: 14 VAIVTGANVGLGFSTTHTLAKNGATVVMACRNADKANSAIAELKKNLPDADLVFMPLDLS 73 Query: 195 YTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYP 374 KS+ R + +R+DLLIN + + + N++G+ L+ P Sbjct: 74 DLKSVKRFAEQFLEQFDRLDLLINNAGVMVPPYQKTVDGFELQMGANYFGHFLLTSLLLP 133 Query: 375 LLNE--NARVVNVSGPAGLLATIENEDI--RKRISD-PTLTEDELVALIQEYEHAAR 530 LL + NAR+VN+S A I +D+ KR S + +L L+ YE + R Sbjct: 134 LLEKTGNARIVNLSSIAHRNGKIHFDDMHFEKRYSKMEAYGQSKLAMLMFSYELSRR 190 >UniRef50_Q9LQ75 Cluster: T1N6.22 protein; n=13; core eudicotyledons|Rep: T1N6.22 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 325 Score = 58.8 bits (136), Expect = 1e-07 Identities = 52/227 (22%), Positives = 108/227 (47%), Gaps = 31/227 (13%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERP----DIEISYLQM 185 VA+V G+ +G+++ ++L + T D+ G ++ L+ D IS+ + Sbjct: 36 VAVVTGSNKGIGFEICRQLANNGI-TVVLTARDENKGLAAVQKLKTENGFSDQAISFHPL 94 Query: 186 DITYTKSIIRLRHYIQDLDERIDLLIN-----------------ITDYVAEKNLSN---- 302 D++ +I L +++ ++D+L+N I + A ++S Sbjct: 95 DVSNPDTIASLAAFVKTRFGKLDILVNNAGVGGANVNVDVLKAQIAEAGAPTDISKIMSD 154 Query: 303 -FEKIRRTLSVNFYGYINFGKLVYPLL--NENARVVNVSGPAGLLATIENEDIRKRISDP 473 +E + + N+YG + + PLL +++ R+V+++ G L + NE + +SD Sbjct: 155 TYEIVEECVKTNYYGVKRMCEAMIPLLQSSDSPRIVSIASTMGKLENVSNEWAKGVLSDA 214 Query: 474 -TLTEDELVALIQEYEHAARRGVEKTEGWG--MNVHAVSKVALNAVT 605 LTE+++ +I EY + G + +GW M+ + +SK A+ A+T Sbjct: 215 ENLTEEKIDEVINEYLKDYKEGALQVKGWPTVMSGYILSKAAVIALT 261 >UniRef50_Q4D5D5 Cluster: Short chain dehydrogenase, putative; n=5; Trypanosomatidae|Rep: Short chain dehydrogenase, putative - Trypanosoma cruzi Length = 298 Score = 58.4 bits (135), Expect = 1e-07 Identities = 45/175 (25%), Positives = 75/175 (42%), Gaps = 7/175 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VALV G +GY ++++ + + D G SL D+++ +L + IT Sbjct: 54 VALVTGGNRGIGYAAVRRMAQLGYC-VLLAARDVQRGEAAAASLRADDMDVQFLHLVITD 112 Query: 198 TKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 S+ ++ +R+D LIN + DY N ++R VNF+ + Sbjct: 113 EASVATAAREVEARYKRLDALINNAAVMDYDNHITPLNVPRMREEFEVNFFAAVMVTNAF 172 Query: 369 YPLL---NENARVVNVSGPAGLLATIENEDIRKRISDPTLTEDELV-ALIQEYEH 521 PL+ ++ R+VNVS P G T+E+ R P T + A + Y H Sbjct: 173 LPLMLRTSDAPRIVNVSTPLGTHETVEHP--HNRYGSPLFTSYKCTKAALNMYTH 225 >UniRef50_Q00RH3 Cluster: OSIGBa0125M19.13 protein; n=9; Oryza sativa|Rep: OSIGBa0125M19.13 protein - Oryza sativa (Rice) Length = 346 Score = 58.0 bits (134), Expect = 2e-07 Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 5/120 (4%) Frame = +3 Query: 276 YVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPLL--NENARVVNVSGPAGLLATIENED 449 ++ ++ ++ + + N+YG + + + PLL + ++VNVS GLL + NED Sbjct: 167 WMRKQGRETYDTAKNGVQTNYYGAKHVIQGLLPLLLSSSEGKIVNVSSALGLLRFLGNED 226 Query: 450 IRKRISD-PTLTEDELVALIQEYEHAARRGVEKTEGW--GMNVHAVSKVALNAVTFLQHR 620 +RK + D LTE+ L ++ + G + GW G + V+KVA+NA T + R Sbjct: 227 LRKELDDIDNLTEERLDEVLASFLKDFEAGELEAHGWPMGSAAYKVAKVAMNAYTRISAR 286 >UniRef50_Q3EZA6 Cluster: Short chain dehydrogenase; n=5; Bacillaceae|Rep: Short chain dehydrogenase - Bacillus thuringiensis serovar israelensis ATCC 35646 Length = 236 Score = 56.8 bits (131), Expect = 4e-07 Identities = 39/151 (25%), Positives = 74/151 (49%), Gaps = 6/151 (3%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMD 188 M A + GA +GY+++++L E + ++ ++ G + SL ++ SY+Q+D Sbjct: 1 MKKYAFITGANKGIGYELVRQLAEKNY-HVFLGARNEQLGQQAVDSLNVSNV--SYIQVD 57 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLIN----ITDYVAEKNLSNFEKIRRTLSVNFYGYINF 356 I+ ++SI I + + + LLIN D+ + N E +R+ VNF+G Sbjct: 58 ISNSQSIQEATKKIHETTDHLHLLINNAGIALDFNTLPSELNIETLRQGFEVNFFGTFQM 117 Query: 357 GKLVYPLL--NENARVVNVSGPAGLLATIEN 443 + PLL + N++++NV+ L N Sbjct: 118 IQAFLPLLKNSSNSKILNVTTDMASLTMFAN 148 >UniRef50_A0BZA9 Cluster: Chromosome undetermined scaffold_139, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_139, whole genome shotgun sequence - Paramecium tetraurelia Length = 250 Score = 56.8 bits (131), Expect = 4e-07 Identities = 42/165 (25%), Positives = 80/165 (48%), Gaps = 1/165 (0%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 203 L+ G LG + K+L H + T D + LK S +D++ + Sbjct: 4 LITGCNRGLGMLLAKELKNNH---VIATARD----IHKLKQALHDQKHCSLEYLDVSNDE 56 Query: 204 SIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIR-RTLSVNFYGYINFGKLVYPLL 380 SI + ++ + + ID+L+N + E L+N + + VN+YG +N K V P + Sbjct: 57 SI---KQFVSTIKQPIDILVNNAGII-ETQLTNKNNLASQVFKVNYYGVLNLTKAVLPYM 112 Query: 381 NENARVVNVSGPAGLLATIENEDIRKRISDPTLTEDELVALIQEY 515 EN +++ +S G L I+N I+++++ +D+L ++QE+ Sbjct: 113 KENGKIIVISSDLGKL-RIQNSVIQEQLN--KCNKDQLEMIVQEF 154 >UniRef50_A0NL67 Cluster: Carbonyl reductase; n=2; Oenococcus oeni|Rep: Carbonyl reductase - Oenococcus oeni ATCC BAA-1163 Length = 257 Score = 56.0 bits (129), Expect = 8e-07 Identities = 35/142 (24%), Positives = 70/142 (49%), Gaps = 5/142 (3%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMD 188 M + L+ GA +G++ K++ + + + +T ++ G N + L++ I +LQ+D Sbjct: 15 MTKIVLITGANKGIGFETAKQIGK-NGWTLLISTRNEERGKNAVHQLQQDGITAEWLQID 73 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFE----KIRRTLSVNFYGYINF 356 + SI + Y+++ ++D LIN + + E ++ + VNF G Sbjct: 74 LNDIASIHKAARYVEERYPKLDGLINNAGISGDMQKNPLELKSSELEQLAKVNFLGNFEM 133 Query: 357 GKLVYPLLNEN-ARVVNVSGPA 419 K P+L+ N R++NV+ PA Sbjct: 134 IKSFTPILSRNHGRILNVTIPA 155 >UniRef50_UPI00006CA45C Cluster: oxidoreductase, short chain dehydrogenase/reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: oxidoreductase, short chain dehydrogenase/reductase family protein - Tetrahymena thermophila SB210 Length = 376 Score = 55.6 bits (128), Expect = 1e-06 Identities = 44/164 (26%), Positives = 82/164 (50%), Gaps = 8/164 (4%) Frame = +3 Query: 132 NILKSLERPDIEISYLQMDITYTKSIIRLRHYIQDLDERIDLLIN--------ITDYVAE 287 NI K ++ IE+ ++D+ +KSI + ++ Q+ +R D+L N + DY + Sbjct: 148 NIQKQKQKCQIEVQ--RLDVADSKSIKQFSNWFQNNFDRYDVLFNNAGVVNKQLDDYNLQ 205 Query: 288 KNLSNFEKIRRTLSVNFYGYINFGKLVYPLLNENARVVNVSGPAGLLATIENEDIRKRIS 467 K E R T+ NF+G I K + P L+++ +++ +S G+L + E ++ +S Sbjct: 206 KKPDQ-ENARWTMQTNFFGTIELTKCLLPNLSQDGKILMMSSNLGIL-QYQGEKGKQFLS 263 Query: 468 DPTLTEDELVALIQEYEHAARRGVEKTEGWGMNVHAVSKVALNA 599 + L E +L+ Q Y + A + + T + H SK LN+ Sbjct: 264 NHNLNEQDLIQAAQNYINNANQN-DTTMFCNSSYH-TSKALLNS 305 >UniRef50_Q28SS3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Jannaschia sp. (strain CCS1) Length = 229 Score = 55.6 bits (128), Expect = 1e-06 Identities = 40/143 (27%), Positives = 71/143 (49%), Gaps = 6/143 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 +AL+ GA +G +V ++L + H + + D G + ERP+ +Q+D+ Sbjct: 6 IALITGANRGIGREVARQLAQDHGLHVLLGSRDLIKGEEAAR--ERPNARA--IQLDVAD 61 Query: 198 TKSIIRLRHYIQDLDERIDLLINIT--DYVAEK--NLSNFEKIRRTLSVNFYGYINFGKL 365 KS+ R I R+D+L+N DY ++ ++++ ++RR N +G + Sbjct: 62 PKSVARAFEQISQEVGRLDVLVNNAGIDYDTDQRASIADLTRVRRAFDTNLFGAWDVAIA 121 Query: 366 VYPLLNE--NARVVNVSGPAGLL 428 PLL + + R+VNVS AG L Sbjct: 122 ATPLLKKGLSPRLVNVSSGAGAL 144 >UniRef50_A1ZM53 Cluster: Short chain dehydrogenase; n=1; Microscilla marina ATCC 23134|Rep: Short chain dehydrogenase - Microscilla marina ATCC 23134 Length = 244 Score = 55.6 bits (128), Expect = 1e-06 Identities = 37/157 (23%), Positives = 81/157 (51%), Gaps = 11/157 (7%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKG-KIYFTTEDDTAGFNILKSLERPDIEISYLQM 185 M VA + GA +G++ ++L + KG + + D G + L+ +++ +L++ Sbjct: 1 MKKVAFITGANKGIGFEASRQLAK--KGITVIMGSRSDQRGKQASEQLKSEGLDVEFLKL 58 Query: 186 DITYTKSIIRLRHYIQDLDERIDLLINITDYV-AEKNLS-------NFEKIRRTLSVNFY 341 DIT +S + YI + ++D+L+N + +E++ + E +R+T VNF+ Sbjct: 59 DITQPESFDEAKKYIDEKYGQLDILVNNAGIIHSEESWGENTTETVSLEALRQTFEVNFF 118 Query: 342 GYINFGKLVYPLLNENAR--VVNVSGPAGLLATIENE 446 G + + + PL+ ++ + + NVS G + ++N+ Sbjct: 119 GLVALTQKLLPLIRKSKQGYITNVSSILGSV-NVQND 154 >UniRef50_A7ANX9 Cluster: Putative uncharacterized protein; n=1; Babesia bovis|Rep: Putative uncharacterized protein - Babesia bovis Length = 389 Score = 55.2 bits (127), Expect = 1e-06 Identities = 45/139 (32%), Positives = 68/139 (48%), Gaps = 5/139 (3%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERP---DIE-ISYLQM 185 VA+V G +S +G +V +L + + K+ T D T G N ++ L + D + I +++M Sbjct: 113 VAIVTGGSSGVGKEVACQLLKWNC-KVVITARDKTKGANAVEYLRKQANVDFKMIQFVEM 171 Query: 186 DITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 365 D+ KSI I + ID LIN +L N K + NF G+ KL Sbjct: 172 DLNDPKSIKLAVEEILKTNASIDFLINNAGIATNVHL-NAYKQEAMFATNFLGHFQLTKL 230 Query: 366 VYP-LLNENARVVNVSGPA 419 + P L+ ARV+NVS A Sbjct: 231 LMPTLVRFKARVINVSSIA 249 >UniRef50_UPI00006CBD6F Cluster: oxidoreductase, short chain dehydrogenase/reductase family protein; n=3; Tetrahymena thermophila SB210|Rep: oxidoreductase, short chain dehydrogenase/reductase family protein - Tetrahymena thermophila SB210 Length = 328 Score = 54.4 bits (125), Expect = 2e-06 Identities = 37/154 (24%), Positives = 76/154 (49%), Gaps = 4/154 (2%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDD-TAGFNILKSLERPDIEISYL 179 D + ++ GA S +G++ K + H K+ D+ TA + L+ ++ Sbjct: 43 DLSNQIIVITGANSGIGFETAKNCVQ-HGAKVVLACRDEITAQQSCLQLNSIKKKSTEFI 101 Query: 180 QMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLS-NFEKIRRTLSVNFYGYINF 356 ++D++ + SI + + + ++D+L+N +A N E +T+ VN++G+ Sbjct: 102 KLDLSDSSSIRQFANIFKKKYSKLDILVNNAGVMAIPNRCLTKEGFEQTIGVNYFGHFLL 161 Query: 357 GKLV--YPLLNENARVVNVSGPAGLLATIENEDI 452 +L+ + L+ RV+NVS A L TI+ +D+ Sbjct: 162 TQLLLDHLKLSSQFRVINVSSVAHLAGTIDFQDL 195 >UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=1; Ralstonia eutropha JMP134|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 258 Score = 54.4 bits (125), Expect = 2e-06 Identities = 36/134 (26%), Positives = 63/134 (47%), Gaps = 3/134 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 +ALV G AS +G ++L + ++YFT + AG L+ + + +L+ D+T Sbjct: 7 IALVTGGASGMGLAFTRRLAQ-EGARVYFTDINGAAGHATESELQGAGLAVVFLRHDVTQ 65 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLS--NFEKIRRTLSVNFYGYINFGKLVY 371 +R+ +I +D R+D+L+N N+ E RTL+VN K Sbjct: 66 ENDWLRVLEHIGAVDGRLDVLVNNAGIAISHNIETCTTEDFDRTLNVNLKSVFLGCKHGL 125 Query: 372 PLLNE-NARVVNVS 410 L+ + ++NVS Sbjct: 126 ALMKQKGGSIINVS 139 >UniRef50_A7QKE7 Cluster: Chromosome chr2 scaffold_112, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr2 scaffold_112, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 208 Score = 54.4 bits (125), Expect = 2e-06 Identities = 37/133 (27%), Positives = 65/133 (48%), Gaps = 7/133 (5%) Frame = +3 Query: 228 IQDLDERIDLLINI--TDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPLL--NENAR 395 +Q L E+ + +N D + E +EK + N+YG + + PLL + ++R Sbjct: 12 VQRLKEKFEYYVNDENVDMLKEIMKRTYEKAEECIRTNYYGTQRVTQSLLPLLQLSPSSR 71 Query: 396 VVNVSGPAGLLATIENEDIRKRISD-PTLTEDELVALIQEYEHAARRGVEKTEGWGM--N 566 +VNVS G L I N ++ + + LTE++L ++Q + + GW + + Sbjct: 72 IVNVSSLRGQLKNIHNHQVKAELENVGELTEEKLDKILQRFLRDFKEDKLGANGWPVIAS 131 Query: 567 VHAVSKVALNAVT 605 + VSK A+NA T Sbjct: 132 AYKVSKAAVNAYT 144 >UniRef50_Q7NNW5 Cluster: Glr0293 protein; n=6; Bacteria|Rep: Glr0293 protein - Gloeobacter violaceus Length = 243 Score = 54.0 bits (124), Expect = 3e-06 Identities = 37/161 (22%), Positives = 74/161 (45%), Gaps = 7/161 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 +A+V G +G++V ++L ++ T+ D G + L+ +++ + +D+T Sbjct: 14 LAVVTGGNRGIGFEVSRQLANFGH-RVILTSRDPEQGKTAAEKLQSEGLDVLFHPLDVTD 72 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNL-------SNFEKIRRTLSVNFYGYINF 356 S L ++++ R+D+L+N + + ++ + +R T N G + Sbjct: 73 PASAEALAGFVRERFGRLDILVNNAGILQDGGADAARLLDADLDMLRTTFETNTLGPVLV 132 Query: 357 GKLVYPLLNENARVVNVSGPAGLLATIENEDIRKRISDPTL 479 + PL+ RVVNVS AG LA + + R+S L Sbjct: 133 AHALVPLMQGRGRVVNVSSGAGQLADMGSGYPAYRVSKTAL 173 >UniRef50_A5B040 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 184 Score = 54.0 bits (124), Expect = 3e-06 Identities = 35/121 (28%), Positives = 59/121 (48%), Gaps = 5/121 (4%) Frame = +3 Query: 273 DYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPLL--NENARVVNVSGPAGLLATIENE 446 D + E +EK + N+YG + + PLL + +AR+VNVS G L I N Sbjct: 55 DMLKEIKQRTYEKAEECIRTNYYGTQRVTQSLLPLLQLSPSARIVNVSSLRGQLKNIHNH 114 Query: 447 DIRKRISD-PTLTEDELVALIQEYEHAARRGVEKTEGWGM--NVHAVSKVALNAVTFLQH 617 ++ + + LTE++L ++Q + + GW + + + VSK A+NA T + Sbjct: 115 QVKAELENVGELTEEKLDKILQRFLRDFKEDKLGANGWPVIASAYKVSKAAVNAYTRITE 174 Query: 618 R 620 R Sbjct: 175 R 175 >UniRef50_A6EJ80 Cluster: Short chain dehydrogenase dehydrogenase; n=1; Pedobacter sp. BAL39|Rep: Short chain dehydrogenase dehydrogenase - Pedobacter sp. BAL39 Length = 264 Score = 53.6 bits (123), Expect = 4e-06 Identities = 42/151 (27%), Positives = 73/151 (48%), Gaps = 8/151 (5%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKG-KIYFTTEDDTAGFNILKSLERPDIE-ISYLQMDIT 194 ALV GA +G+Q++K+L E KG +Y + G + ++ L+ IE I +Q+D+T Sbjct: 24 ALVTGANKGIGFQIVKQLAE--KGFFVYLGCRNPEKGLSAVEKLKADGIEHIEAIQLDVT 81 Query: 195 YTKSIIRLRHYIQDLDERIDLLINIT----DYVAEKNLSNFEKIRRTLSVNFYGYINFGK 362 S+ R I + +D+LIN D+ S ++ + N +G + + Sbjct: 82 SQASVDAARELIGTKTDTLDVLINNAGISGDFQQSALASTADQYQLVYDTNVFGVVRVTQ 141 Query: 363 LVYPLLNENA--RVVNVSGPAGLLATIENED 449 LL+++A R+VNVS L+ + D Sbjct: 142 AFIDLLSKSAEPRIVNVSTAMASLSQASDLD 172 >UniRef50_A2QT81 Cluster: Function: mouse WOX1 is an enhancer of tumor necrosis factor; n=7; Pezizomycotina|Rep: Function: mouse WOX1 is an enhancer of tumor necrosis factor - Aspergillus niger Length = 456 Score = 53.6 bits (123), Expect = 4e-06 Identities = 39/165 (23%), Positives = 71/165 (43%), Gaps = 4/165 (2%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERP---DIEIS 173 D VAL+ G A +GY++ + + K+Y T + G ++ +++ + +I Sbjct: 17 DLTGRVALITGGALGIGYEIARAFV-LNGAKVYMTNRKEEQGQAAIEQIKKEAGENAQIE 75 Query: 174 YLQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYIN 353 + D+ I + + ++R+DLLI + + I R VN+ G Sbjct: 76 WFPCDMGNLNEIKEVFEDFRKKEDRLDLLILSAGINVNQYGETHDHIDRHFEVNWLGQFY 135 Query: 354 FGKLVYPLLNENARVVNVSGPAGLLATIENEDIR-KRISDPTLTE 485 LVYPLL + +++ N P + T E + K + TL E Sbjct: 136 VVNLVYPLLRKTSKLPNTPAPRIVFETSEQHRMAPKNVHFATLEE 180 >UniRef50_UPI0000E476E0 Cluster: PREDICTED: similar to Carbonyl reductase 1, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Carbonyl reductase 1, partial - Strongylocentrotus purpuratus Length = 364 Score = 40.7 bits (91), Expect(2) = 5e-06 Identities = 24/125 (19%), Positives = 57/125 (45%), Gaps = 4/125 (3%) Frame = +3 Query: 27 VVGAASNLGYQVLKKLTET--HKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYT 200 V GA +G+ +++ L + +G +Y + D+ G ++ L+ + +Q+DI Sbjct: 138 VTGANKGIGFGIVRALCKELGERGVVYLASRDEGRGEKAVQELKGEGLNPRCIQLDICNN 197 Query: 201 KSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRR--TLSVNFYGYINFGKLVYP 374 I ++ Y +D +D+L+N + + + I+ T+ N + + + + P Sbjct: 198 DHISKVADYFRDTYGGLDILVNNAGIAFKAAATEPDSIQAPVTVETNVFATLRLCRALIP 257 Query: 375 LLNEN 389 L+ + Sbjct: 258 LIRSH 262 Score = 32.3 bits (70), Expect(2) = 5e-06 Identities = 15/41 (36%), Positives = 26/41 (63%) Frame = +3 Query: 492 LVALIQEYEHAARRGVEKTEGWGMNVHAVSKVALNAVTFLQ 614 L+ LI+ + AA+ +K GWG + + VSK+ + A+T +Q Sbjct: 255 LIPLIRSHGSAAKEEKKKELGWGSSNYGVSKLGVIALTRIQ 295 >UniRef50_Q2W431 Cluster: Dehydrogenase with different specificities; n=2; Magnetospirillum|Rep: Dehydrogenase with different specificities - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 248 Score = 53.2 bits (122), Expect = 5e-06 Identities = 35/144 (24%), Positives = 71/144 (49%), Gaps = 4/144 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VAL+ G AS +GY +K + E + + AG L + ++++D+T Sbjct: 7 VALITGGASGIGYCTVKSMAELG-ADVLIADINVEAGEKAAAELTAKGFKAEFVRLDVTD 65 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDY-VAEKNLSNFEK-IRRTLSVNFYGYINFGKLVY 371 +I R++ ++ R+D+L N+ + + + N + I + +S+N G I + + Sbjct: 66 KANIARVKEHVVATRGRLDILCNVAGWGHIQPFVDNDDAFIAKVMSLNLTGPIELIRAFF 125 Query: 372 PLLNE--NARVVNVSGPAGLLATI 437 PL+ E ++VNV+ AG + ++ Sbjct: 126 PLMIEKKTGKIVNVASDAGRVGSL 149 >UniRef50_A3WIM4 Cluster: Putative dehydrogenase; n=1; Idiomarina baltica OS145|Rep: Putative dehydrogenase - Idiomarina baltica OS145 Length = 239 Score = 53.2 bits (122), Expect = 5e-06 Identities = 37/146 (25%), Positives = 69/146 (47%), Gaps = 5/146 (3%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMD 188 M V LV G +G +++K+L H +Y + G NI ++ E +++ ++ +D Sbjct: 1 MSKVFLVTGGNKGIGKEIVKQLG-LHGHTVYLGARNVEEGRNIAEAFEASGLDVRFVYID 59 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLS---NFEKIRRTLSVNFYGYINFG 359 +T S +I+ +D LIN + + +L+ + E +R T N++G + Sbjct: 60 LTDVNSQKEAADHIKSKSGLLDGLINNAGMINDFDLASSVSLESLRETFETNYFGTVMVT 119 Query: 360 KLVYPLLNENAR--VVNVSGPAGLLA 431 + + LL R +VNVS G +A Sbjct: 120 QNMLSLLRAGERKVIVNVSTGLGSMA 145 >UniRef50_A7IE62 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Xanthobacter sp. (strain Py2) Length = 242 Score = 52.8 bits (121), Expect = 7e-06 Identities = 40/137 (29%), Positives = 65/137 (47%), Gaps = 6/137 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 +ALV GA +G + L + D G L + + +Q+D T Sbjct: 7 IALVSGANRGIGLAIAAGLARRKGVNVLLGCRDLDRGKTASLPLLAEGLRVRPVQLDATD 66 Query: 198 TKSIIRLRHYIQDLDERIDLLINIT----DYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 365 S+ L H+I++ R+D L+N DY + +LS E+I++TL VN G + + Sbjct: 67 EASVSSLAHFIENEYGRLDALVNNAGIGLDY--DPSLSVVERIQKTLDVNVVGALRLTEA 124 Query: 366 VYPLLNENA--RVVNVS 410 + PLL ++ R+VNVS Sbjct: 125 MVPLLAKSTRPRIVNVS 141 >UniRef50_A4X6Z1 Cluster: Short-chain dehydrogenase/reductase SDR; n=8; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Salinispora tropica CNB-440 Length = 263 Score = 52.8 bits (121), Expect = 7e-06 Identities = 41/143 (28%), Positives = 63/143 (44%), Gaps = 6/143 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 +AL+ GA +GY++ ++L E + D+T G + SL I L++D+T Sbjct: 27 IALITGANKGIGYEIARQLGERGH-TVLVGARDETRGRQAVDSLVAQGIVAVPLRLDVTD 85 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKN----LSNFEKIRRTLSVNFYGYINFGKL 365 SI I+ R+D+L+N N + +R+ N G ++ Sbjct: 86 PASISAAAAEIEQRYGRLDVLVNNAGIAGAANGAPSTVRADDLRQVYETNVLGVVSVTNA 145 Query: 366 VYPLLNE--NARVVNVSGPAGLL 428 V PLL ARVVNVS G L Sbjct: 146 VLPLLRRAVAARVVNVSSHLGSL 168 >UniRef50_A4QYV9 Cluster: Putative uncharacterized protein; n=1; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 349 Score = 52.4 bits (120), Expect = 9e-06 Identities = 31/127 (24%), Positives = 58/127 (45%), Gaps = 2/127 (1%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSL--ERPDIEISYLQMDITY 197 LV G AS +G + ++ +++ A + ++ E PD++I +LQ+D+ Sbjct: 49 LVTGGASGIGAAFVAEIARHSPAQVWIADLRPEAAEKAISAISAECPDVKIDFLQIDLGD 108 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPL 377 +S+ R ER+D+L+N + K + + VNF G+ +L+ P Sbjct: 109 AESVKRAASEFLSRTERLDVLLNNAGILPAKGWTTKDGYESMFGVNFVGHARLTELLLPR 168 Query: 378 LNENARV 398 L E A + Sbjct: 169 LMETAAI 175 >UniRef50_A7PQQ5 Cluster: Chromosome chr6 scaffold_25, whole genome shotgun sequence; n=15; cellular organisms|Rep: Chromosome chr6 scaffold_25, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 379 Score = 52.0 bits (119), Expect = 1e-05 Identities = 29/106 (27%), Positives = 54/106 (50%), Gaps = 5/106 (4%) Frame = +3 Query: 303 FEKIRRTLSVNFYGYINFGKLVYP--LLNENARVVNVSGPAGLLATIENEDIRKRISD-P 473 +E + N+YG + ++P LL+ + R+VNVS G L + NE +R ++D Sbjct: 210 YELAEECVKTNYYGTKGVTEALFPCLLLSNSGRIVNVSSGLGSLKFVSNERVRMELNDVD 269 Query: 474 TLTEDELVALIQEYEHAARRGVEKTEGW--GMNVHAVSKVALNAVT 605 L+ + L ++ E+ + + +GW + + +SK A+NA T Sbjct: 270 VLSVERLDEIVNEFLNDVKENTLHDKGWPTQTSAYTISKAAMNAYT 315 Score = 35.1 bits (77), Expect = 1.5 Identities = 19/83 (22%), Positives = 41/83 (49%), Gaps = 1/83 (1%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIE-ISYLQMDITY 197 A+V GA+ +G ++ ++L ++ + T D+ G + L + + + Q+D+ Sbjct: 85 AVVTGASKGIGLEICRQLA-SNGVMVVLTARDEKRGLEAVAKLHESSLSNVVFHQLDVMD 143 Query: 198 TKSIIRLRHYIQDLDERIDLLIN 266 SI L +I ++D+L+N Sbjct: 144 ANSITSLATFIVTRYGKLDILVN 166 >UniRef50_Q5AWR2 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 245 Score = 51.6 bits (118), Expect = 2e-05 Identities = 39/143 (27%), Positives = 66/143 (46%), Gaps = 6/143 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTED----DTAGFNILKSLERPDIEISYLQM 185 + L+ GA LG++ K L I + D D A + L +L +S +Q+ Sbjct: 6 IVLISGANRGLGFEAAKCLVHLANYHIILGSRDLLKADKAA-DTLHALPNLKCSVSTVQL 64 Query: 186 DITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 365 D+T SI + YI+ R+D+L+N S+ + +R +L N G + + Sbjct: 65 DVTDKSSITAAKSYIEATFSRLDILVNNAAIYLLNPTSSVDALRASLDTNVIGVVALTEE 124 Query: 366 VYPLLNENA--RVVNVSGPAGLL 428 + PLL ++A R++ VS G L Sbjct: 125 LLPLLRKSASPRLILVSSSNGSL 147 >UniRef50_Q1VG25 Cluster: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR; n=3; Vibrionales|Rep: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR - Vibrio alginolyticus 12G01 Length = 244 Score = 51.2 bits (117), Expect = 2e-05 Identities = 38/151 (25%), Positives = 75/151 (49%), Gaps = 6/151 (3%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMD 188 M +ALV G + LG + +KL E+ I + A ++L SL R + +++ +++ Sbjct: 1 MSKLALVTGGSGGLGAAICRKLAESGYRVILTYNSNQKAAEDVLSSLPRNE-HLAF-KLN 58 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEK--IRRTLSVNFYGYIN 353 + + +I +L+H + ++ +++DLL+N +T +VA +L + + + VN Sbjct: 59 VADSSAIEQLKHQVSEISDKLDLLVNCAGMTKFVAHSDLQSLDDQLFDQIFQVNVRAPFA 118 Query: 354 FGKLVYPLLNE-NARVVNVSGPAGLLATIEN 443 + P L + N VVN++ A A N Sbjct: 119 MVRAFEPWLKQANGCVVNITSIAAQTAMGSN 149 >UniRef50_A4EYN4 Cluster: Putative uncharacterized protein; n=2; Rhodobacteraceae|Rep: Putative uncharacterized protein - Roseobacter sp. SK209-2-6 Length = 285 Score = 50.4 bits (115), Expect = 4e-05 Identities = 38/151 (25%), Positives = 67/151 (44%), Gaps = 5/151 (3%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKG-KIYFTTEDDTAGFNILKSLERPDIEISYLQM 185 M L+ G +S LG + L +H G ++Y T D + + E + + LQ+ Sbjct: 1 MSKTVLITGTSSGLGLETA--LAASHAGHRVYATMRDPGKSSALRAAAEASGLGLEILQL 58 Query: 186 DITYTKSIIRLRHYIQDLDERIDLLINI--TDYVAEKNLSNFEKIRRTLSVNFYGYINFG 359 D+ +SI + + ID LIN Y+ ++ E I + + VNF G + Sbjct: 59 DVQDPESIKTTVAEVLRREGHIDTLINNAGAGYLRNIEQASDEDINQVMDVNFMGVLRCT 118 Query: 360 KLVYPLL--NENARVVNVSGPAGLLATIENE 446 + V P + ++ ++N+S GL+ NE Sbjct: 119 RAVLPHMRARKSGHIINISSVGGLVGQPFNE 149 >UniRef50_A4BUN6 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Nitrococcus mobilis Nb-231|Rep: Short-chain dehydrogenase/reductase SDR - Nitrococcus mobilis Nb-231 Length = 243 Score = 50.0 bits (114), Expect = 5e-05 Identities = 35/152 (23%), Positives = 68/152 (44%), Gaps = 14/152 (9%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 +A++ GA LG++ ++L K T+ D G L+ +++ Y +D+T Sbjct: 7 IAVITGANRGLGFETARQLARRGY-KAVLTSRDAVQGKAAADKLQGEALDVGYHPLDVTR 65 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSN------------FEKIRRTLSVNFY 341 S+ RL ++ + R+D+L+N E+ ++ E + L N + Sbjct: 66 ADSVQRLAGFLDNAFGRLDVLVNNAGIFPEQASAHGAHSAPNVFEMPLESLHENLQTNAF 125 Query: 342 GYINFGKLVYPLLNEN--ARVVNVSGPAGLLA 431 G + + + PL+ + R+VN+S G LA Sbjct: 126 GALRLIQTIVPLMRRHGYGRIVNISSGYGQLA 157 >UniRef50_A2R3R8 Cluster: Contig An14c0180, complete genome; n=3; Pezizomycotina|Rep: Contig An14c0180, complete genome - Aspergillus niger Length = 249 Score = 50.0 bits (114), Expect = 5e-05 Identities = 37/143 (25%), Positives = 70/143 (48%), Gaps = 5/143 (3%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLER-PDIE--ISYLQMD 188 + L+ GA +G++ K L + + + D G K+LE P I+ +S +Q+D Sbjct: 7 LVLITGANQGIGFETAKNLILSDNYHVILGSRDPAKGEEAAKTLEAVPGIKGSVSSIQID 66 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 +T +S+ I+ R+D+L+N + K+ + E +R+ L VN G ++ + Sbjct: 67 VTDDQSVDNAAAQIKAQYGRLDILVNNAAMSSMKHPPSREAMRQILDVNVVGALSTTEAF 126 Query: 369 YPLLNENA--RVVNVSGPAGLLA 431 LL ++ R+V VS G ++ Sbjct: 127 LDLLRNSSEKRLVFVSSSTGSIS 149 >UniRef50_Q03F37 Cluster: Short-chain dehydrogenase of various substrate specificities; n=1; Pediococcus pentosaceus ATCC 25745|Rep: Short-chain dehydrogenase of various substrate specificities - Pediococcus pentosaceus (strain ATCC 25745 / 183-1w) Length = 261 Score = 49.6 bits (113), Expect = 7e-05 Identities = 37/144 (25%), Positives = 66/144 (45%), Gaps = 6/144 (4%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYT 200 A++ GA S LG ++ + + + K + + + + L D+T Sbjct: 4 AVITGAGSGLGQKIAILNSTRYDNLVLIGRNSKKLNATAEKCIVKGENRVFCLACDLTNE 63 Query: 201 KSIIRLRHYIQDLDERIDLLINITDYVAEKNL--SNFEKIRRTLSVNFYGYINFGKLVYP 374 + I + +I +DLL+N +NL +FE+I RT + + G I F +L+ P Sbjct: 64 EQIRQTGAWIDSHLGTVDLLVNNAGLGYFENLLSQSFEQIERTFATDLTGMIKFTRLMLP 123 Query: 375 LL----NENARVVNVSGPAGLLAT 434 L+ E A +VN++ AG +AT Sbjct: 124 LMVDHVGEAADIVNIASIAGKIAT 147 >UniRef50_A1FW82 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=8; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Stenotrophomonas maltophilia R551-3 Length = 283 Score = 49.6 bits (113), Expect = 7e-05 Identities = 34/142 (23%), Positives = 66/142 (46%), Gaps = 7/142 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 +ALV GA +G + +++L + + + +TA LK L+ + + +Q+D+T Sbjct: 46 IALVTGATRGIGAETVRQLAQAGVHTLLAGRKRETAVEQALK-LQAEGLPVEAIQLDVTD 104 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEK-----NLSNFEKIRRTLSVNFYGYINFGK 362 SI ++ R+D+L+N + E + + + +RT N Y + + Sbjct: 105 AASIAEAVEQVRQRHGRLDILVNNAGIMIENPAQAPSEQSLDTWKRTFDTNVYALVAVTQ 164 Query: 363 LVYPLLNE--NARVVNVSGPAG 422 PL+ + + R+VNVS G Sbjct: 165 AFLPLVRQAKSGRIVNVSSMLG 186 >UniRef50_A0M3M9 Cluster: Short-chain dehydrogenase/reductase family protein; n=14; Bacteroidetes|Rep: Short-chain dehydrogenase/reductase family protein - Gramella forsetii (strain KT0803) Length = 295 Score = 49.2 bits (112), Expect = 9e-05 Identities = 40/144 (27%), Positives = 72/144 (50%), Gaps = 7/144 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 + L+ GA+S +G + L + + K+Y T+ E D +++Q+D+T Sbjct: 32 IVLITGASSGIGKSIATYLAKRNF-KVYGTSRSKK---------ESSDSVFNFVQLDVTN 81 Query: 198 TKSIIRLRHYIQDLDERIDLLIN-----ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGK 362 +SII + I + RID+LIN IT + E S +I++ N++G +N K Sbjct: 82 EQSIIAAINEISKKEGRIDVLINNAGVGITGPIEETPES---EIKKAFETNYFGPLNMIK 138 Query: 363 LVYPLLNEN--ARVVNVSGPAGLL 428 V P++ +N ++NV+ AG + Sbjct: 139 NVLPVMRKNNGGLIINVTSIAGYM 162 >UniRef50_UPI0000D5685B Cluster: PREDICTED: similar to CG31235-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG31235-PA - Tribolium castaneum Length = 345 Score = 48.8 bits (111), Expect = 1e-04 Identities = 41/155 (26%), Positives = 70/155 (45%), Gaps = 5/155 (3%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKG-KIYFTTEDDTAGFNILKSLER--PDIEISYLQMD 188 + ++ G +S +G K+L + KG +I + G L+ L R P+ E +D Sbjct: 49 IVIITGGSSGIGLTTAKELAK--KGARIILAVRNAERGKRALEYLLRECPEAEAIIKLVD 106 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 + SI + I ER+D+LIN + + T+S N++G L+ Sbjct: 107 LNDFVSIREFANQINLEYERVDILINNAGIIFHPFRKTVDGNEMTISTNYFGPFLLTHLL 166 Query: 369 YPLL--NENARVVNVSGPAGLLATIENEDIRKRIS 467 LL ++N RV+N+S A L I+ +D+ S Sbjct: 167 LNLLSKSDNGRVINLSAVAHLRGKIDLDDLNSEKS 201 >UniRef50_A0RXB6 Cluster: Short-chain alcohol dehydrogenase; n=2; Thermoprotei|Rep: Short-chain alcohol dehydrogenase - Cenarchaeum symbiosum Length = 276 Score = 48.4 bits (110), Expect = 2e-04 Identities = 34/142 (23%), Positives = 65/142 (45%), Gaps = 4/142 (2%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMD 188 M VALV G++S +GY+ L ++ T D + G +L++ + ++IS ++D Sbjct: 1 MEKVALVTGSSSGIGYETSLALARAGY-LVHATMRDTSKGAGLLEAANKEGLKISVSRLD 59 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSN--FEKIRRTLSVNFYGYINFGK 362 + I R+D+L+N Y ++ + ++ R NF+G I + Sbjct: 60 VDEPGGAAETVSRIVKESGRLDVLVNNAGYGIFGSVEDVTIDEFRAQFETNFFGVIRMIQ 119 Query: 363 LVYPLL--NENARVVNVSGPAG 422 P++ + +VN+S AG Sbjct: 120 AAAPVMRGQKGGCIVNISSVAG 141 >UniRef50_UPI000023D4D3 Cluster: hypothetical protein FG11091.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG11091.1 - Gibberella zeae PH-1 Length = 334 Score = 48.0 bits (109), Expect = 2e-04 Identities = 35/152 (23%), Positives = 69/152 (45%), Gaps = 8/152 (5%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKGK---IYFTTEDDTAGFNILKSLER--PDIEISYLQM 185 A+ +GA S +G +K+L GK IY +A ++ L + P I +++ Sbjct: 25 AVFLGATSGIGRSTVKQLAIATDGKSPTIYLVGRSASATTALIAELRQGNPSATIEFIER 84 Query: 186 DITYTKSIIRLRHYIQDLDERIDLLINITDYVA-EKNLSNFEKIRRTLSVNFYGYINFGK 362 D++ K + I +E++D+L +++ E EK+ + + +Y + + Sbjct: 85 DVSLVKEADAVMQEISKREEKVDILFMSVGFMSFEGRKETNEKLEPSFTTRYYSRVRSIQ 144 Query: 363 LVYPLLNE--NARVVNVSGPAGLLATIENEDI 452 + PLLN N VVN+ G+ + +D+ Sbjct: 145 TLLPLLNRSANPHVVNILA-GGMEGPLVEDDL 175 >UniRef50_Q1QYL7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Chromohalobacter salexigens DSM 3043|Rep: Short-chain dehydrogenase/reductase SDR - Chromohalobacter salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768) Length = 248 Score = 48.0 bits (109), Expect = 2e-04 Identities = 38/151 (25%), Positives = 70/151 (46%), Gaps = 7/151 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 +AL+ G +GY V KKL + + D + + SL+ I L +DIT Sbjct: 8 IALITGGTKGIGYAVCKKLCSLGV-HVIMSGRDSSKLRKAVNSLKYDGHVIEGLLLDITD 66 Query: 198 TKSIIRLRHYIQDLDERIDLLIN-----ITDYVAEKNLSNFEKIRRTLSVNFYGYINF-G 359 +SI R+Y+++ +D+L+N + Y + + +T + N +G I+ Sbjct: 67 NESIHCARNYVRNKYGHLDILVNNAAIRVEQYGKAPSEQPLSEWLKTFNTNLFGTISITN 126 Query: 360 KLVYPLLNE-NARVVNVSGPAGLLATIENED 449 L+ P+ + + R++NVS G T ++D Sbjct: 127 ALLEPVKSSPSGRIINVSSLLGSTTTHTHKD 157 >UniRef50_Q140F5 Cluster: Putative short-chain dehydrogenase/oxidoreductase; n=1; Burkholderia xenovorans LB400|Rep: Putative short-chain dehydrogenase/oxidoreductase - Burkholderia xenovorans (strain LB400) Length = 245 Score = 48.0 bits (109), Expect = 2e-04 Identities = 34/143 (23%), Positives = 70/143 (48%), Gaps = 6/143 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 +ALV GA LG++ +++L + ++ D AG L +++ + +D+ Sbjct: 9 IALVTGATRGLGFETVRQLAASGV-RVLLGARDTHAGEAKAAELRAEGLDVRPIAIDLNN 67 Query: 198 TKSIIRLRHYIQDLDERIDLLIN----ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 365 + + I L R+D+L+N ++D +++N + +R + +NF + + Sbjct: 68 AATFDQAAKEIDALFGRLDILVNNAGVMSDADGFPSVANPQAMRDVIEINFIATVIVTQN 127 Query: 366 VYPLL--NENARVVNVSGPAGLL 428 + PLL +++ R+VNVS G L Sbjct: 128 MLPLLRKSKHGRIVNVSSRVGSL 150 >UniRef50_Q081K4 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Alteromonadales|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella frigidimarina (strain NCIMB 400) Length = 276 Score = 48.0 bits (109), Expect = 2e-04 Identities = 38/139 (27%), Positives = 64/139 (46%), Gaps = 5/139 (3%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 203 +V GAAS LG + K H ++ + AG + + ++ + ++ DIT T Sbjct: 11 VVTGAASGLGKALALKWASQH-AEVCVADINKPAGEQVCQEIQALGGKAFFVPCDITNTD 69 Query: 204 SIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKI---RRTLSVNFYGYINFGKLVYP 374 SI L + + + ID+LIN VA + E I R + +N +G +N + P Sbjct: 70 SITALVQVLNERWQHIDVLINNAG-VASADKIEVEPILQWRWVMEINLFGIVNMCQQFVP 128 Query: 375 LLNEN--ARVVNVSGPAGL 425 + + +VNV+ AGL Sbjct: 129 IFKQQGVGSIVNVASQAGL 147 >UniRef50_A5FMQ3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Flavobacterium johnsoniae UW101|Rep: Short-chain dehydrogenase/reductase SDR - Flavobacterium johnsoniae UW101 Length = 246 Score = 48.0 bits (109), Expect = 2e-04 Identities = 33/143 (23%), Positives = 72/143 (50%), Gaps = 8/143 (5%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIE-ISYLQMDITYT 200 L+ GA ++G ++ K+L++ +Y + D G I+K L + + I +Q+D+T Sbjct: 5 LITGANRSIGLEITKQLSKQGLF-VYLGSRDLEKGNEIVKELNKDGFQNIKAIQIDVTNP 63 Query: 201 KSIIRLRHYIQDLDERIDLLINIT-----DYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 365 SI+ + +++ ++D+LIN + + ++ + I+ NF+G I+ + Sbjct: 64 DSILAAKKIVENEQGKLDILINNAGISGGQFPQTASDTSVKDIKNVFETNFFGVISVTQA 123 Query: 366 VYPLL--NENARVVNVSGPAGLL 428 LL +++ R+ N++ G L Sbjct: 124 FLELLKKSDSPRISNITSGLGSL 146 >UniRef50_UPI00006CAF29 Cluster: oxidoreductase, short chain dehydrogenase/reductase family protein; n=3; Tetrahymena thermophila SB210|Rep: oxidoreductase, short chain dehydrogenase/reductase family protein - Tetrahymena thermophila SB210 Length = 338 Score = 47.6 bits (108), Expect = 3e-04 Identities = 36/155 (23%), Positives = 71/155 (45%), Gaps = 5/155 (3%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLE--RPDIEISY 176 D V +V G S +G++ K L + K+ T ++ G N +K L RP+ + Sbjct: 49 DLSNEVIIVTGGNSGIGFETCKDLVR-NGAKVILATRNEQRGQNAIKELNKIRPNSS-EF 106 Query: 177 LQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVA-EKNLSNFEKIRRTLSVNFYGYIN 353 +++D++ SI + + +++ LIN +A + + + N +G+ Sbjct: 107 MKLDLSDLTSIRLFANEFKSKYNKLNCLINNAGIMAISTRVLTKDGFESQIGTNHFGHFL 166 Query: 354 FGKLVYPLLNENA--RVVNVSGPAGLLATIENEDI 452 L++ +L + R++NVS A + TI +DI Sbjct: 167 LTNLLFDVLKQTPQFRIINVSSRAHIRNTINLDDI 201 >UniRef50_Q8YZV3 Cluster: NADPH-dependent carbonyl reductase; n=5; Nostocaceae|Rep: NADPH-dependent carbonyl reductase - Anabaena sp. (strain PCC 7120) Length = 248 Score = 47.6 bits (108), Expect = 3e-04 Identities = 34/152 (22%), Positives = 69/152 (45%), Gaps = 9/152 (5%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 +A+V G+ LGY + +KL + + T+ ++ G + L ++ Y +D+T Sbjct: 7 IAVVTGSNRGLGYAISRKLAQIGI-HVILTSRNEADGLAAKQQLSSEGLDADYCVLDVTN 65 Query: 198 TKSIIRLRHYIQDLDERIDLL-----INITDYVAEKNL--SNFEKIRRTLSVNFYGYINF 356 S+ + ++ + ++D+L IN T E +L E +R T N + Sbjct: 66 DVSVQKFTKWLHETYSKVDILVNNAGINPTTKPEESSLLTVQLETMRFTWETNVLAVVRI 125 Query: 357 GKLVYPLLNEN--ARVVNVSGPAGLLATIENE 446 + + PL+ R+VN+S L++I ++ Sbjct: 126 TQALIPLMQAQNYGRIVNISTEMASLSSISDD 157 >UniRef50_Q89V05 Cluster: Dehydrogenase; n=4; Proteobacteria|Rep: Dehydrogenase - Bradyrhizobium japonicum Length = 312 Score = 47.6 bits (108), Expect = 3e-04 Identities = 49/189 (25%), Positives = 81/189 (42%), Gaps = 8/189 (4%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSL-ER-PDIEISYLQMDIT 194 A+V GA LGY+ L + T +D G ++ + ER PD I+Y +D+ Sbjct: 17 AVVTGATGGLGYETAMALAGAG-AIVILTGRNDAKGLRAIEGICERFPDALIAYEHLDLA 75 Query: 195 YTKSIIRLRHYIQDLDERIDLLINITDYVA-EKNLSNFEKIRRTLSVNFYGYINFGKLVY 371 S+ +E++DLL+N +A K + L N+ G+ + Sbjct: 76 SLSSVADFAKRFAAGNEQLDLLVNNAGVMALPKRQQTEDGFEMQLGTNYLGHYALTARLL 135 Query: 372 PLLN--ENARVVNVSGPAGLLATIENEDIR-KRISDP--TLTEDELVALIQEYEHAARRG 536 P L + +R+VN+S A I +D++ KR P + +L L+ E RR Sbjct: 136 PQLRRAKASRIVNLSSLAHRSGAINFDDLQGKRSYRPWRAYCQSKLAMLMFALE-LQRRS 194 Query: 537 VEKTEGWGM 563 + GWG+ Sbjct: 195 L--AAGWGV 201 >UniRef50_A6D9G4 Cluster: Putative short-chain dehydrogenase/reductase; n=1; Vibrio shilonii AK1|Rep: Putative short-chain dehydrogenase/reductase - Vibrio shilonii AK1 Length = 246 Score = 47.6 bits (108), Expect = 3e-04 Identities = 39/151 (25%), Positives = 71/151 (47%), Gaps = 6/151 (3%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMD 188 M +ALV GA +G + L E I + +A ++ + S+L++D Sbjct: 1 MQKIALVTGAYQGIGLATSELLMEQGFHVIMADIQSCSA---LVNDFRQKGYTASHLKLD 57 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLIN----ITDYVAEKNLSNFEKIRRTLSVNFYGYINF 356 + + + + I++ R+D+L+N + D +L + + RR + VN G Sbjct: 58 LAMSSVFPAVANKIEEQFGRLDVLVNNAAILVDLGRHPSLIDEDTYRRVIEVNQIGPFLL 117 Query: 357 GKLVYPLLNEN--ARVVNVSGPAGLLATIEN 443 + + PLL ++ AR+VNVS AG LA + + Sbjct: 118 TRALTPLLKKSSQARIVNVSSQAGQLAQLSD 148 >UniRef50_A7RNX1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 282 Score = 47.6 bits (108), Expect = 3e-04 Identities = 36/150 (24%), Positives = 71/150 (47%), Gaps = 6/150 (4%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFN----ILKSLERPDIEISYLQMDI 191 ++ GA S +G +V + L K ++ D G I++S D+E+ ++D+ Sbjct: 5 IITGANSGIGMEVARDLA-WRKARVIMACRDVHKGMKAAAEIVQSAGNMDVEVK--KLDL 61 Query: 192 TYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 371 SI + + + R+D+LIN Y+ + +K+ TL VN+ G L+ Sbjct: 62 ASFASIREFAKEVNEEESRVDVLINNAGYLGSQK-KTVDKLEYTLQVNYLGPFLLTNLLL 120 Query: 372 PLLNEN--ARVVNVSGPAGLLATIENEDIR 455 L + +R++NVS A+I+ ++++ Sbjct: 121 GKLKTSSPSRIINVSSHQHKKASIDFDNLQ 150 >UniRef50_Q17CG7 Cluster: Short-chain dehydrogenase; n=2; Culicidae|Rep: Short-chain dehydrogenase - Aedes aegypti (Yellowfever mosquito) Length = 328 Score = 47.2 bits (107), Expect = 3e-04 Identities = 36/138 (26%), Positives = 66/138 (47%), Gaps = 6/138 (4%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLER---PDIEISYLQMDIT 194 ++ GA S +G ++++L+ + + T+G + K LER PDI + +++++ Sbjct: 42 VITGATSGIGLALVQELS-SRNCHLVLGCRSLTSGILLRKQLERQSGPDITVDIFELNLS 100 Query: 195 YTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYP 374 KS+ R + +L + I L+N + + I +TL VNF L+ P Sbjct: 101 SLKSVARFVDNVSNLRKPIYALVNNAGIFYARPGLTVDGIEQTLQVNFLSQYLLTILLLP 160 Query: 375 LLN---ENARVVNVSGPA 419 L +N+RV+ VS A Sbjct: 161 KLKQYPDNSRVIIVSSKA 178 >UniRef50_UPI0000D573DB Cluster: PREDICTED: similar to CG7675-PB, isoform B; n=2; Tribolium castaneum|Rep: PREDICTED: similar to CG7675-PB, isoform B - Tribolium castaneum Length = 340 Score = 46.8 bits (106), Expect = 5e-04 Identities = 38/133 (28%), Positives = 63/133 (47%), Gaps = 3/133 (2%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFN-ILKSLERPDIEISYLQMDITY 197 A+V G S +G++ +L I ED T N I+ +IE +L D+T Sbjct: 50 AIVTGGGSGIGFETALQLASRGCRVIIADREDATKTKNKIIDLTNNTNIETKHL--DLTS 107 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPL 377 +SI R I + ++R+D+LIN + N + + T+ VN +G L+ L Sbjct: 108 FQSIRRFAKEINETEDRLDILINNAGAGSVGNKHTDDGLHITMQVNHFGPFLLTHLLADL 167 Query: 378 LNENA--RVVNVS 410 L ++A R++ VS Sbjct: 168 LKKSAPSRIIFVS 180 >UniRef50_A3CMH2 Cluster: Dehydrogenase, putative; n=1; Streptococcus sanguinis SK36|Rep: Dehydrogenase, putative - Streptococcus sanguinis (strain SK36) Length = 271 Score = 46.8 bits (106), Expect = 5e-04 Identities = 38/133 (28%), Positives = 64/133 (48%), Gaps = 3/133 (2%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 203 +++GA+ +LG +V + ++Y D + ++ I +DIT + Sbjct: 16 VIIGASGSLG-RVYTRAFHQAGARLYLLGRDIE---KLKMFVQEFSSFIPISSVDITSEE 71 Query: 204 SIIRLRHYIQDLDERIDLLINITDYVAEKNLS--NFEKIRRTLSVNFYGYINFGKLVYPL 377 S+ + IQ+ E ID++IN T + K+LS + E I +TL +N G I K+ PL Sbjct: 72 SLKNVVSEIQEWSECIDIVINATGFDVRKSLSAHSLEDIEQTLLINLSGAILISKIFLPL 131 Query: 378 L-NENARVVNVSG 413 L NE + SG Sbjct: 132 LANEKGATIVHSG 144 >UniRef50_A1ZT55 Cluster: Carbonyl reductase, NADPH 1; n=1; Microscilla marina ATCC 23134|Rep: Carbonyl reductase, NADPH 1 - Microscilla marina ATCC 23134 Length = 229 Score = 46.8 bits (106), Expect = 5e-04 Identities = 50/209 (23%), Positives = 88/209 (42%), Gaps = 9/209 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 + LV G +G+++ ++L T K+ T + L +++ +D++ Sbjct: 6 IILVTGGNRGIGFEMCRQLA-TMGHKVILTARTSDKVQEAVVRLANTGLKVQGEVLDVSK 64 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEK--IRRTLSVNFYGYINFGKLVY 371 T S I+ +D+LIN +++L + + + TL N YG I F + + Sbjct: 65 TGSFKVFAQRIEAKYAYLDVLINNAGIFLKESLQSLTEQVLDETLKTNLYGPIFFSRELI 124 Query: 372 PLL--NENARVVNVSGPAGLLATIENEDIRKRISDPTLTEDELVALIQEYE----HAARR 533 PLL ++ R+VNVS G ++ + R+S L L L EY +A Sbjct: 125 PLLHNSKGGRIVNVSSFLGTMSDMNRNYTAYRLSKAALNAFTL-HLSVEYPLLKINACHP 183 Query: 534 GVEKTEGWGMNV-HAVSKVALNAVTFLQH 617 G +T+ G+N + K A V H Sbjct: 184 GHVQTDMGGVNAQRTIEKGAETPVWLAVH 212 >UniRef50_UPI000155BDDB Cluster: PREDICTED: similar to NADP+ dependent prostaglandin dehydrogenase, partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to NADP+ dependent prostaglandin dehydrogenase, partial - Ornithorhynchus anatinus Length = 134 Score = 46.4 bits (105), Expect = 6e-04 Identities = 24/83 (28%), Positives = 42/83 (50%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VALV G +G +++ L G + T D G +++ L+ + + Q+DIT Sbjct: 45 VALVTGGNRGIGLAIVRALGRRFSGTVILTARDPGQGQAVVQVLKEEGLSPLFHQLDITD 104 Query: 198 TKSIIRLRHYIQDLDERIDLLIN 266 +S+ LR Y+ D +D+L+N Sbjct: 105 PQSVRTLRDYLLDTFGGLDVLVN 127 >UniRef50_A6QK68 Cluster: Oxidoreductase; n=12; Staphylococcus aureus|Rep: Oxidoreductase - Staphylococcus aureus (strain Newman) Length = 234 Score = 46.4 bits (105), Expect = 6e-04 Identities = 37/152 (24%), Positives = 63/152 (41%), Gaps = 5/152 (3%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMD 188 M + L+ G LGY + L K+Y + +D G + L + Y+Q+D Sbjct: 1 MTKIVLITGGNKGLGYASAEALKALGY-KVYIGSRNDVRGQQASQKLG-----VHYVQLD 54 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFG 359 +T S+ + I + + R+D+LIN I+ + + + N +G + Sbjct: 55 VTSDYSVKNAYNMIAEKEGRLDILINNAGISGQFSAPSKLTPRDVEEVYQTNVFGIVRMM 114 Query: 360 KLVYPLL--NENARVVNVSGPAGLLATIENED 449 PLL +E VVNVS G + N + Sbjct: 115 NTFVPLLEKSEQPVVVNVSSGLGSFGMVTNPE 146 >UniRef50_Q4PDD2 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 340 Score = 46.4 bits (105), Expect = 6e-04 Identities = 30/140 (21%), Positives = 64/140 (45%), Gaps = 2/140 (1%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLER--PDIEISY 176 D VA+V G S LG +L + K+Y + ++ ++ +++ P +I + Sbjct: 11 DLTGRVAIVTGGNSGLGEVSCLELAR-NGAKVYMASRTESKAQEAIQKIKQAIPKADIHF 69 Query: 177 LQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINF 356 LQ+++T ++ + ++R+D+L+N +A + I + N G+ F Sbjct: 70 LQLNLTELAAVRKAAEDFLSREQRLDILLNNAGVMATPYTFTKDGIELQVGTNVVGHYLF 129 Query: 357 GKLVYPLLNENARVVNVSGP 416 L+ P L + +++ S P Sbjct: 130 TMLLLPTLYKTSKLPEYSAP 149 >UniRef50_UPI0000D55E90 Cluster: PREDICTED: similar to CG11200-PB, isoform B; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG11200-PB, isoform B - Tribolium castaneum Length = 357 Score = 46.0 bits (104), Expect = 8e-04 Identities = 49/210 (23%), Positives = 87/210 (41%), Gaps = 13/210 (6%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDI---EISYLQMD 188 VA++ G A +G +V+K L + + AG +L+ + +++ ++D Sbjct: 67 VAVITGGARGIGAEVVKMLLRCDI-HVIIGCRNTQAGEQVLQKCRDSGVTTGDVTVYKLD 125 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 I+ S+ + + +I+ LIN + + + + S N+ G+ L+ Sbjct: 126 ISVLDSVKSFAKVVAEKHPKINYLINNAGIMFGPYIESRDGYESQFSTNYLGHFLLTHLL 185 Query: 369 YPLL------NENARVVNVSGPAGLLATIENEDIRKR---ISDPTLTEDELV-ALIQEYE 518 P L N +R+VNVS A L+ I+ EDI R IS + +L L Y Sbjct: 186 LPQLCAAGTQNLKSRIVNVSSCAHLVGEIKFEDINNRHQYISGEAYAQSKLAQVLFTNY- 244 Query: 519 HAARRGVEKTEGWGMNVHAVSKVALNAVTF 608 V K E + +H+V +N F Sbjct: 245 ---LESVCKKENMPVQLHSVHPGIVNTELF 271 >UniRef50_Q8YW93 Cluster: Alr1722 protein; n=6; Bacteria|Rep: Alr1722 protein - Anabaena sp. (strain PCC 7120) Length = 311 Score = 46.0 bits (104), Expect = 8e-04 Identities = 34/148 (22%), Positives = 66/148 (44%), Gaps = 3/148 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLER-PDIEISYLQMDIT 194 +A+V G++S +GY+ + L I D + K L++ D ++ +++D+ Sbjct: 18 LAIVTGSSSGIGYETARVLANKQASVIIAVRNLDKGNKALAKILQQNKDADVKLMELDLA 77 Query: 195 YTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINF-GKLVY 371 S+ + R+DLLIN + + N G+ G+L+ Sbjct: 78 NLASVKNFAENFRKNYLRLDLLINNAGVMIPPYSKTTDGFELQFGTNHLGHFALTGQLLE 137 Query: 372 PLLN-ENARVVNVSGPAGLLATIENEDI 452 L++ E +R+VNVS A + I+ +D+ Sbjct: 138 FLISTEGSRIVNVSSGAHNMGKIDFDDL 165 >UniRef50_Q6F7B8 Cluster: Fatty acyl-CoA reductase; n=6; Moraxellaceae|Rep: Fatty acyl-CoA reductase - Acinetobacter sp. (strain ADP1) Length = 303 Score = 46.0 bits (104), Expect = 8e-04 Identities = 32/144 (22%), Positives = 65/144 (45%), Gaps = 6/144 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VAL+ GA+S +G + K++ + +T + ++E+ + S D+T Sbjct: 25 VALITGASSGIGLTIAKRIAAAGAHVLLVARTQETLE-EVKAAIEQQGGQASIFPCDLTD 83 Query: 198 TKSIIRLRHYIQDLDERIDLLINITD----YVAEKNLSNFEKIRRTLSVNFYGYIN--FG 359 +I +L I + +D LIN ++ F RT+ +N++G + Sbjct: 84 MNAIDQLSQQIMASVDHVDFLINNAGRSIRRAVHESFDRFHDFERTMQLNYFGAVRLVLN 143 Query: 360 KLVYPLLNENARVVNVSGPAGLLA 431 L + + +N +++N+S G+LA Sbjct: 144 LLPHMIKRKNGQIINISS-IGVLA 166 >UniRef50_A7RSA6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 288 Score = 46.0 bits (104), Expect = 8e-04 Identities = 33/144 (22%), Positives = 64/144 (44%), Gaps = 8/144 (5%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTET--HKGKIYFTTEDDTAGFNILKSLERPDIEISYL--QM 185 V L+ G ++ +G L + + K+Y T + IL+ R + + + Q+ Sbjct: 6 VVLITGCSTGIGLAAALLLAKDDGRRFKVYATMRN-LEKRGILEEAARRQLGDTLIVKQL 64 Query: 186 DITYTKSIIRLRHYIQDLDERIDLLINI--TDYVAEKNLSNFEKIRRTLSVNFYGYINFG 359 D+T +S+ + I + RID+L+N + +R +VNF+G + Sbjct: 65 DVTSDESVTEVLQSIYSAERRIDVLVNNAGVGLIGVLETHTMSLVREMFNVNFFGVVRLT 124 Query: 360 KLVYPLLNEN--ARVVNVSGPAGL 425 K V P + EN ++N++ G+ Sbjct: 125 KAVIPKMKENHSGHIINITSIGGI 148 >UniRef50_Q4PDJ8 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 281 Score = 46.0 bits (104), Expect = 8e-04 Identities = 52/213 (24%), Positives = 96/213 (45%), Gaps = 18/213 (8%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKL-----------TETHKGKIYFTTED----DTAGFNILKSLER 155 ALV G LGY ++++L + + K IY + D + A +I L + Sbjct: 4 ALVSGGNRGLGYGIVRRLANEFPTSPLSTSSSDKLTIYLGSRDIAKGEAAKNSITSELAQ 63 Query: 156 PDIE---ISYLQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTL 326 ++ I Q+D T +SI++L +L E +D+LIN + +N +T+ Sbjct: 64 DTLDRVSIEVRQLDTTSHESIVKLG---SELKEGVDILINNAGIAMDGFDANV--ATQTV 118 Query: 327 SVNFYGYINFGKLVYPLLNENARVVNVSGPAGLLATIENEDIRKRISDPTLTEDELVALI 506 + N+Y + + + + + R+VN++ G+L +++R R + D AL+ Sbjct: 119 ATNYYAVQDMIQNIN--VKDGGRIVNIASLTGVLKGF-GDNVRDRFRNSETIAD-TDALM 174 Query: 507 QEYEHAARRGVEKTEGWGMNVHAVSKVALNAVT 605 +E++ G K GW +A SK + A T Sbjct: 175 KEFQQVVADGSWKENGWKGVAYATSKSGVIAYT 207 >UniRef50_P80365 Cluster: Corticosteroid 11-beta-dehydrogenase isozyme 2; n=39; Euteleostomi|Rep: Corticosteroid 11-beta-dehydrogenase isozyme 2 - Homo sapiens (Human) Length = 405 Score = 46.0 bits (104), Expect = 8e-04 Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 6/139 (4%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 203 L+ G S G + KKL + E ++ G L++ P + + LQMD+T Sbjct: 86 LITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAIELRTCCSPRLRL--LQMDLTKPG 143 Query: 204 SIIRLRHYIQDLDERIDL--LINITDY---VAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 I R+ + + L L+N + VA+ LS R + VNF+G + K + Sbjct: 144 DISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGL 203 Query: 369 YPLL-NENARVVNVSGPAG 422 PLL + R+V V PAG Sbjct: 204 LPLLRSSRGRIVTVGSPAG 222 >UniRef50_Q83D17 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=3; Coxiella burnetii|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Coxiella burnetii Length = 281 Score = 45.6 bits (103), Expect = 0.001 Identities = 30/132 (22%), Positives = 62/132 (46%), Gaps = 4/132 (3%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 203 L+ GA+S +G + L + +H+ + T D+ A + + + +E+ D+ Sbjct: 23 LITGASSGIG-KALALVYASHQHALLLTGRDEDALNQVAQKCRQYSVEVFIYAKDLCLPD 81 Query: 204 SIIRLRHYIQDLDERIDLLINITDYVAEKNLSN--FEKIRRTLSVNFYGYINFGKLVYPL 377 ++ L +I++ +IDLLIN +N S F + + L VN G + + + P Sbjct: 82 AVQSLMKFIEEKQLKIDLLINNAGAGCYRNFSEIPFNSLEQMLRVNIDGLVKLTRQLLPS 141 Query: 378 LNENAR--VVNV 407 + + + +VN+ Sbjct: 142 MIKQGKGSIVNI 153 >UniRef50_Q18SE9 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Desulfitobacterium hafniense|Rep: Short-chain dehydrogenase/reductase SDR - Desulfitobacterium hafniense (strain DCB-2) Length = 280 Score = 45.6 bits (103), Expect = 0.001 Identities = 25/134 (18%), Positives = 65/134 (48%), Gaps = 5/134 (3%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 203 L+ GA+S +G + +L ++ + + + F + +++E+ +S D+ + Sbjct: 32 LITGASSGIGEALAYQLADS-ECHLILVARTEAKLFQVKQNIEQKKAAVSIFPADLREPE 90 Query: 204 SIIRLRHYIQDLDERIDLLINITDYVAEK----NLSNFEKIRRTLSVNFYGYINFGKLVY 371 + L ++I+ L +D+ +N ++ +L + RT+++N+ + + Sbjct: 91 QVKELLNFIEQLPAGLDVFVNNAGLSIKRGIKDSLDRYHDFTRTMAINYLAPVQLALSLI 150 Query: 372 PLLNEN-ARVVNVS 410 PLL +N +++N+S Sbjct: 151 PLLEKNKGQIINIS 164 >UniRef50_Q12HC0 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=23; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 284 Score = 45.6 bits (103), Expect = 0.001 Identities = 38/145 (26%), Positives = 67/145 (46%), Gaps = 5/145 (3%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMD 188 M +ALV GA+S +G ++L++ K+Y T+ G +S E L +D Sbjct: 4 MNKIALVTGASSGIGEVTAQRLSKAGY-KVYGTSR--RGGQAGQQSFEM-------LPLD 53 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDY---VAEKNLSNFEKIRRTLSVNFYGYINFG 359 +T +S+ + L+ RIDLL+N + A S+ E+ + NF+G + Sbjct: 54 VTKNESVEAAVQKLMQLEGRIDLLVNNAGFGVAAAGAEESSIEQAQSMFDTNFFGIVRMT 113 Query: 360 KLVYPLLNE--NARVVNVSGPAGLL 428 + V P + + R++N+ G L Sbjct: 114 RAVVPHMRRQGSGRIINIGSVFGFL 138 >UniRef50_A1G528 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Salinispora arenicola CNS205|Rep: Short-chain dehydrogenase/reductase SDR - Salinispora arenicola CNS205 Length = 237 Score = 45.6 bits (103), Expect = 0.001 Identities = 35/140 (25%), Positives = 63/140 (45%), Gaps = 5/140 (3%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VALV GA +G + +++L E ++Y G ++ + +L++D+T Sbjct: 10 VALVTGANKGIGLETVRRLVEAGY-RVYLGARSKERGQAAAEA-----VGAHFLELDVTC 63 Query: 198 TKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 S+ +++ D +D+L+N IT V + + + I L N GY+ Sbjct: 64 DASVRPAVAFVEQADGHLDVLVNNAGITGPVRDPHDYTADDITEVLLTNVVGYVRLIHAF 123 Query: 369 YPLLNEN--ARVVNVSGPAG 422 PLL ++ R+VNV G Sbjct: 124 LPLLEKSDAPRIVNVGSGLG 143 >UniRef50_Q1DUA6 Cluster: Putative uncharacterized protein; n=1; Coccidioides immitis|Rep: Putative uncharacterized protein - Coccidioides immitis Length = 316 Score = 45.6 bits (103), Expect = 0.001 Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 6/149 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTE-THKGKIYFTTEDDTAGFNILKSLER--PDIEISYLQMD 188 V + VGA S +G L+K K ++Y + G ++L+ L PD E ++ D Sbjct: 22 VYVFVGATSGIGENALRKFARLAAKPRVYIVGRNLVVGESLLRDLRESNPDGEFIFIHKD 81 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVA-EKNLSNFEKIRRTLSVNFYGYINFGKL 365 I+ K + I + R+DLL Y + E + ++ +Y I K Sbjct: 82 ISLVKDAEDVCAEIASKETRLDLLFLSAGYFPWDGRQDTVEGLDAAMATRYYTRILLAKR 141 Query: 366 VYPLLNEN--ARVVNVSGPAGLLATIENE 446 + PLL + RVV+V G +E + Sbjct: 142 LAPLLEASPAGRVVSVLYATGSTRLVETD 170 >UniRef50_UPI0000587D40 Cluster: PREDICTED: similar to Retinol dehydrogenase 8 like; n=4; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Retinol dehydrogenase 8 like - Strongylocentrotus purpuratus Length = 302 Score = 45.2 bits (102), Expect = 0.001 Identities = 35/145 (24%), Positives = 69/145 (47%), Gaps = 7/145 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLT-ETHKGKIYFTTEDDTAGFNILKSLERPDIE--ISYLQMD 188 VA++ G +S +G + + KG I + T + A L+ + + Q+D Sbjct: 5 VAIITGCSSGIGLSTAVMMAKDPSKGYIVYATMRNLAKKGDLEKAAGATLNKTLFITQLD 64 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVAEK--NLSNFEKIRRTLSVNFYGYINFGK 362 +T SI R + +RID+L+N + + L +++R VNF+G ++ + Sbjct: 65 VTRGDSIKRAVKDVFTKHKRIDILVNNAGHGSSGYIELVTDQQMRALFDVNFFGVVHLIQ 124 Query: 363 LVYPLLNE--NARVVNVSGPAGLLA 431 V P++ + + R+++VS G+ A Sbjct: 125 EVLPIMKKQRSGRIISVSSVGGITA 149 >UniRef50_UPI0000D5714C Cluster: PREDICTED: similar to CG2070-PA; n=2; Tribolium castaneum|Rep: PREDICTED: similar to CG2070-PA - Tribolium castaneum Length = 320 Score = 44.8 bits (101), Expect = 0.002 Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 3/149 (2%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKGKIYFTTED-DTAGFNILKSLERPDIEISYLQMDITY 197 ALV GA S LGYQ + L I D + + I+K+ P+I ++D+T Sbjct: 34 ALVTGANSGLGYQTVLNLASRGCTVIMADVADMEESKKQIIKATNNPNIITK--KIDLTS 91 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPL 377 KS+ I + +++D+L N + + + +N++G+ L+ L Sbjct: 92 FKSVRNFATEILNSVDKLDILFNNAGIGVSPSDKTGDGYNPVMQINYFGHFLLTHLLIDL 151 Query: 378 LNENA--RVVNVSGPAGLLATIENEDIRK 458 L +A R+V+ S LLA N ++K Sbjct: 152 LKRSAPSRIVSTS---SLLAYTNNLSVKK 177 >UniRef50_UPI00004996DD Cluster: 3-oxoacyl-(acyl-carrier protein) reductase; n=1; Entamoeba histolytica HM-1:IMSS|Rep: 3-oxoacyl-(acyl-carrier protein) reductase - Entamoeba histolytica HM-1:IMSS Length = 265 Score = 44.8 bits (101), Expect = 0.002 Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 1/84 (1%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDI-EISYLQMDIT 194 VAL+ G S +G ++++LTE K + F G +I L +I ++ D+T Sbjct: 7 VALITGGTSGIGEAIVRQLTE-QKCNVIFIGRRKELGESISHELNNKHFGQIDFIPFDVT 65 Query: 195 YTKSIIRLRHYIQDLDERIDLLIN 266 K L H +Q+ R+DLL+N Sbjct: 66 NFKEYDSLVHIVQEKYNRLDLLVN 89 >UniRef50_Q2Y990 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Nitrosospira multiformis ATCC 25196|Rep: Short-chain dehydrogenase/reductase SDR - Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849) Length = 247 Score = 44.4 bits (100), Expect = 0.002 Identities = 29/133 (21%), Positives = 62/133 (46%), Gaps = 2/133 (1%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VA+V GA+ +G ++ + L + +D A + ++++ E ++ D++ Sbjct: 9 VAIVTGASRGIGAEIARTLGGAGANVVVNYAKDREAAEAVCTAIQQAGAEAIAIKADVSN 68 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNF--EKIRRTLSVNFYGYINFGKLVY 371 + + RL + +R+D+L+N + + +S+ ++ R L VN G + Sbjct: 69 SAEVCRLFDAAIERFQRLDILVNNAGVLLSRKMSDISDDEFDRVLDVNVKGVFYALREAA 128 Query: 372 PLLNENARVVNVS 410 L + RVVN+S Sbjct: 129 VRLEDGGRVVNLS 141 >UniRef50_Q1IP06 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain dehydrogenase/reductase SDR - Acidobacteria bacterium (strain Ellin345) Length = 344 Score = 44.4 bits (100), Expect = 0.002 Identities = 30/124 (24%), Positives = 57/124 (45%), Gaps = 3/124 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTET-HKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDIT 194 VAL+ GA+S G +++ ++ D + + + P I Q+DIT Sbjct: 65 VALITGASSGFGLLTAVEMSAAGYRVVATMRNPDRRSKLDEALAARNPSTPIDVRQLDIT 124 Query: 195 YTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNF--EKIRRTLSVNFYGYINFGKLV 368 + +I R+ + RID+L+N + L + +++RR NF+G++ K V Sbjct: 125 DSAAIPRVIDEVVATHGRIDVLVNNAGFALAGFLEDISLDELRRQFDTNFFGHVAVTKAV 184 Query: 369 YPLL 380 P++ Sbjct: 185 LPVM 188 >UniRef50_A0JXQ7 Cluster: Short-chain dehydrogenase/reductase SDR; n=11; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Arthrobacter sp. (strain FB24) Length = 277 Score = 44.4 bits (100), Expect = 0.002 Identities = 39/139 (28%), Positives = 66/139 (47%), Gaps = 4/139 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VA V GA++ +G++ +KL+ +G FT ++ L+ + + L +D+T Sbjct: 5 VAFVTGASTGIGFEAARKLSG--QG---FTVYAGARRVEKMEPLKAFGVNV--LALDVTD 57 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFE--KIRRTLSVNFYGYINFGKLVY 371 S+ I + RID+L+N Y + +L E + RR VN +G +LV Sbjct: 58 EASMAAAVGGILEAHGRIDVLVNNAGYGSYGSLEEVELAEGRRQFDVNVFGLARMTQLVL 117 Query: 372 PLLNENA--RVVNVSGPAG 422 P + A R++NVS G Sbjct: 118 PAMRAAAQGRIINVSSIGG 136 >UniRef50_Q48I17 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Pseudomonas syringae pv. phaseolicola 1448A|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) Length = 282 Score = 44.0 bits (99), Expect = 0.003 Identities = 40/149 (26%), Positives = 67/149 (44%), Gaps = 4/149 (2%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMD 188 M V L+ GAA +G + +L +G + D +L D Y+ +D Sbjct: 1 MKTVVLITGAAGGIGQAICAQLIR--RGMQLILADIDEKQLRVLAESLGEDA-FPYV-VD 56 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLIN--ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGK 362 +T +S+ L YI+ R+D+LIN V + + E I R L++N + + Sbjct: 57 LTNQESLAGLMTYIESEFGRLDVLINNAAIAVVEAFDTRSVESISRELNINLVAPLILTR 116 Query: 363 LVYPLL--NENARVVNVSGPAGLLATIEN 443 L PLL + +ARV++ G+ T E+ Sbjct: 117 LAIPLLKRSNDARVISTVSLGGVFPTPES 145 >UniRef50_Q3A5G9 Cluster: Short-chain alcohol dehydrogenase-like protein; n=1; Pelobacter carbinolicus DSM 2380|Rep: Short-chain alcohol dehydrogenase-like protein - Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) Length = 266 Score = 44.0 bits (99), Expect = 0.003 Identities = 35/143 (24%), Positives = 64/143 (44%), Gaps = 5/143 (3%) Frame = +3 Query: 18 VALVVGAASN-LGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDIT 194 VALV G N G Q ++ L E ++ T+ D K L +E+ L +D+ Sbjct: 20 VALVTGGTGNGYGSQAVRALAEAG-ATVFITSRDPDRAQQTAKDLRESGLEVQGLGLDLE 78 Query: 195 YTKSIIRLRHYIQDLDERIDLLIN--ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 +SI + I R+D+L+N +++ + + + L+VN G + + Sbjct: 79 SEQSIAHVIDTIISKTGRLDILVNNACSNHFESFETVSLKDWNQVLAVNITGTMLISRAT 138 Query: 369 YP--LLNENARVVNVSGPAGLLA 431 P L N+ ++N+S G++A Sbjct: 139 APHMLQNDGGVMINLSSIYGVVA 161 >UniRef50_A6CZ65 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Vibrio shilonii AK1|Rep: Short-chain dehydrogenase/reductase SDR - Vibrio shilonii AK1 Length = 233 Score = 44.0 bits (99), Expect = 0.003 Identities = 40/144 (27%), Positives = 70/144 (48%), Gaps = 7/144 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFN-ILKSLERPDIEISYLQMDIT 194 +A+V GA LG +V ++L +G I T + +K L ++ + Q+DIT Sbjct: 8 IAIVTGANRGLGKEVSRQLAA--QGDIVIVTARQLSDAQQAVKELGWDNLLAA--QLDIT 63 Query: 195 YTKSIIRLRHYIQDLDERIDLLIN--ITDYVAEKNLSNFE--KIRRTLSVNFYGYINFGK 362 SI L ++ +D+LIN Y +N++N + ++ + N +G + Sbjct: 64 DEGSITHLVERVKQRFSVVDVLINNAAIHYDTWQNVTNADLTTVKEAMDTNVFGAWRMTQ 123 Query: 363 LVYPLL--NENARVVNVSGPAGLL 428 + PLL ++ AR+VN+S AG L Sbjct: 124 ALLPLLQSSQQARIVNISSGAGAL 147 >UniRef50_Q869L6 Cluster: Similar to Lactococcus lactis (Subsp. lactis) (Streptococcus lactis). Oxidoreductase; n=2; Dictyostelium discoideum|Rep: Similar to Lactococcus lactis (Subsp. lactis) (Streptococcus lactis). Oxidoreductase - Dictyostelium discoideum (Slime mold) Length = 290 Score = 44.0 bits (99), Expect = 0.003 Identities = 37/141 (26%), Positives = 68/141 (48%), Gaps = 7/141 (4%) Frame = +3 Query: 27 VVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDI--EISYLQMDITYT 200 V G +S LG ++ +L + K+ T + KS P++ + ++ D+T Sbjct: 14 VTGTSSGLGLNLVTQLAKKPNTKVVAITRNPAE----TKSRIDPELLENVFIIKADVTNE 69 Query: 201 KSIIRLRHYIQDLDERIDLLINITDYV---AEKNLSNFEKIRRTLSVNFYGYINFGKLVY 371 +S+ + RID ++N + A + +SN E++R+ VNF+G +N + V Sbjct: 70 ESVKESIKQTMEKFGRIDCVVNNAGFGIAGAVEEISN-EEMRKIFDVNFFGLLNVIRNVN 128 Query: 372 PLLNE--NARVVNVSGPAGLL 428 P+L E + + N+S AG L Sbjct: 129 PILREQRSGFIFNISSVAGWL 149 >UniRef50_Q5CMZ5 Cluster: ENSANGP00000010899; n=2; Cryptosporidium|Rep: ENSANGP00000010899 - Cryptosporidium hominis Length = 380 Score = 44.0 bits (99), Expect = 0.003 Identities = 32/138 (23%), Positives = 62/138 (44%), Gaps = 4/138 (2%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNI---LKSLERPDIEISYLQMDIT 194 ++ G + +G + +K+L ++ F D A N+ L S+ P +I ++ D++ Sbjct: 95 VITGCSRGIGLETVKQLASWGVSELIFCCRDIAAMENVKNQLTSIRLPPNKIHSIECDLS 154 Query: 195 YTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYP 374 S+ I ++ID+LIN +A + + N+ G+ + + P Sbjct: 155 SLHSVELCSRKILSTVDKIDILINNAGIMAPP-FQLINGVEKQFMTNYLGHYHLTTNLIP 213 Query: 375 LLNEN-ARVVNVSGPAGL 425 LL + R++NVS A L Sbjct: 214 LLQRSKCRIINVSSIAHL 231 >UniRef50_Q0UKX1 Cluster: Predicted protein; n=1; Phaeosphaeria nodorum|Rep: Predicted protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 316 Score = 44.0 bits (99), Expect = 0.003 Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 3/129 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYF---TTEDDTAGFNILKSLERPDIEISYLQMD 188 V LV G + LG Q + L +IY T + +KS EI +L +D Sbjct: 18 VILVTGGNAGLGKQTITYLAAHSPARIYLAARTASKAESAIADIKSQVPNACEIVHLPLD 77 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 +T SI + + R+D+LIN +A + E N G+ KL+ Sbjct: 78 LTSFSSIASAADTFKSRESRLDILINNAGIMAPPYSTTKEGYEIQFGTNHMGHALLTKLL 137 Query: 369 YPLLNENAR 395 P L E A+ Sbjct: 138 LPTLLETAK 146 >UniRef50_Q2S7V4 Cluster: Short-chain alcohol dehydrogenase-like protein; n=1; Hahella chejuensis KCTC 2396|Rep: Short-chain alcohol dehydrogenase-like protein - Hahella chejuensis (strain KCTC 2396) Length = 288 Score = 43.6 bits (98), Expect = 0.004 Identities = 34/138 (24%), Positives = 58/138 (42%), Gaps = 4/138 (2%) Frame = +3 Query: 27 VVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTKS 206 + GAAS LG + + ++ F D G I+ SL P+ Y +D+T + Sbjct: 11 ITGAASGLGLATARHFL-SRGWRVAFADVQDETGSAIVASLGLPENRAFYQHVDVTKVRD 69 Query: 207 IIRLRHYIQDLDERIDLLINITDYVAEKNLSN--FEKIRRTLSVNFYGYINFGKLVYPLL 380 I R I + +D+LIN A + E + ++ G + K PL Sbjct: 70 IQAWRRKIVETWGGLDILINNAGVAAHGGIGEAPLEDWEWVIDIDLMGVVRGCKEFAPLF 129 Query: 381 --NENARVVNVSGPAGLL 428 + ++VN++ AGL+ Sbjct: 130 KRQRSGQIVNIASMAGLV 147 >UniRef50_Q4YKD8 Cluster: Putative uncharacterized protein; n=2; Plasmodium (Vinckeia)|Rep: Putative uncharacterized protein - Plasmodium berghei Length = 236 Score = 43.6 bits (98), Expect = 0.004 Identities = 27/97 (27%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Frame = +3 Query: 132 NILKSLERPDIEISYLQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEK 311 N+LK PD +I +++D+ KSI +YI ++D+++N ++ K L Sbjct: 107 NLLKKY--PDAKIYCVELDLGSYKSIENCANYILKTFPKVDIIVNNAGFLNRK-LEYING 163 Query: 312 IRRTLSVNFYGYINFGKLVY-PLLNENARVVNVSGPA 419 + T +N+YG+ L+Y +L +VN+S A Sbjct: 164 LESTFFINYYGHFYLINLLYNRILTSGTLIVNLSSIA 200 >UniRef50_A0BRV4 Cluster: Chromosome undetermined scaffold_123, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_123, whole genome shotgun sequence - Paramecium tetraurelia Length = 254 Score = 43.6 bits (98), Expect = 0.004 Identities = 41/196 (20%), Positives = 97/196 (49%), Gaps = 2/196 (1%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGF--NILKSLERPDIEISYLQMDI 191 + L+ GA LG ++ + L E + + +D+ N+ K+ + ++EI +D+ Sbjct: 6 IVLITGANRGLGLKLAEVLAEKYSLILTARKQDELEKTKQNLEKNFQ--NLEIKTHLLDV 63 Query: 192 TYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 371 + +S+ +L+ ++ +ID+L+N N + R+ + +N G I+ + + Sbjct: 64 SSKESVRKLKDWLVSQHLKIDVLVN--------NAGVNQDPRKIIDINLIGTIDVTEQLL 115 Query: 372 PLLNENARVVNVSGPAGLLATIENEDIRKRISDPTLTEDELVALIQEYEHAARRGVEKTE 551 L ++ +V+ +S G L + +D+++ + T++E++ L +E+ + K + Sbjct: 116 STLKDDGKVILISSILGKLEN-QPQDLKETLLKKK-TKEEIIQLSEEF-------ILKNQ 166 Query: 552 GWGMNVHAVSKVALNA 599 + + V++ SK LNA Sbjct: 167 EY-LTVYSASKALLNA 181 >UniRef50_Q2TWW2 Cluster: Dehydrogenases with different specificities; n=2; Trichocomaceae|Rep: Dehydrogenases with different specificities - Aspergillus oryzae Length = 323 Score = 43.6 bits (98), Expect = 0.004 Identities = 45/172 (26%), Positives = 73/172 (42%), Gaps = 14/172 (8%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDT---AGFNILKSLERPDIEIS 173 D VALV G + LG + + +L + +IY +T A + LK ++EI+ Sbjct: 28 DLSGKVALVTGGNAGLGKETILQLAKHRPQRIYLAARSETKAQAAISSLKGSLSNNVEIT 87 Query: 174 YLQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYIN 353 +L +D+ KSI R+D+LI ++ L N G+ Sbjct: 88 WLPLDLMSIKSIQTAAQTFNAESSRLDILILNAGVMSLPPGETEMGHEIQLGTNHTGHFL 147 Query: 354 FGKLVYPLL-------NENARVVNVSGPAGLLA----TIENEDIRKRISDPT 476 KL+ P L N + RVV++S LA TI ++D K+++ T Sbjct: 148 LTKLLLPTLLKTAEEPNSDVRVVSLSSIGHNLAPSFETILDQDRLKKVNTNT 199 >UniRef50_Q0CKZ3 Cluster: Predicted protein; n=5; Pezizomycotina|Rep: Predicted protein - Aspergillus terreus (strain NIH 2624) Length = 345 Score = 43.6 bits (98), Expect = 0.004 Identities = 35/133 (26%), Positives = 60/133 (45%), Gaps = 4/133 (3%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTE-THKGKIYFTTEDDTAGFNILKSLE--RPDIEISYLQMD 188 VA+ VG S + L T KIY +A + S++ + ++LQ D Sbjct: 22 VAVFVGGTSGIALSTALALARHTPSPKIYLIGRSQSAAATAIASMKTINSSAQPTFLQTD 81 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNL-SNFEKIRRTLSVNFYGYINFGKL 365 I+ KS+ + I +++++LL Y+ K E + R L +++Y + F Sbjct: 82 ISLLKSVDSVCAEIAAREKKVNLLFMTPGYMTIKGRDETTEGLDRKLVLHYYARMRFMTN 141 Query: 366 VYPLLNENARVVN 404 + PLLN A+ VN Sbjct: 142 LLPLLNAAAQDVN 154 >UniRef50_A2R758 Cluster: Putative sequencing error; n=1; Aspergillus niger|Rep: Putative sequencing error - Aspergillus niger Length = 244 Score = 43.6 bits (98), Expect = 0.004 Identities = 36/139 (25%), Positives = 57/139 (41%), Gaps = 7/139 (5%) Frame = +3 Query: 27 VVGAASNLGYQVLKKLTETHKG-KIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 203 + GA LG+ V KKL H G + D T G + L+ + + + +D+T Sbjct: 11 ITGANQGLGFAVAKKLATDHPGYHVLMGYRDATKGEEAIAKLKSRGLTVEGVMIDVTDDT 70 Query: 204 SIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRT----LSVNFYGYINFGKLVY 371 S+ R R+D+LIN ++E +R T +N ++ + Sbjct: 71 SMXRAAEQASAQFGRLDVLINNAGVISEGRSPEGTSLRHTWQTGFDINITAHVITPEAFV 130 Query: 372 PLLNENA--RVVNVSGPAG 422 PLL + A VV VS G Sbjct: 131 PLLEKAALPLVVFVSSALG 149 >UniRef50_UPI0000F2B793 Cluster: PREDICTED: similar to 17-beta hydroxysteroid dehydrogenase 2; n=1; Monodelphis domestica|Rep: PREDICTED: similar to 17-beta hydroxysteroid dehydrogenase 2 - Monodelphis domestica Length = 339 Score = 43.2 bits (97), Expect = 0.006 Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 6/141 (4%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 203 L+ G S +G+ + K L E + G LK + S QMDIT Sbjct: 75 LITGGDSGIGHALSKYLDELGFTVFVGVLNEKGPGAEALK--KTCSKRTSVFQMDITKPA 132 Query: 204 SIIRLRHYIQDLDERIDL--LIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 I ++ + + ++ L ++N I + + L E R+ + VNF+G + K Sbjct: 133 QIREVQARVAEKVQQTGLWAIVNNAGILGSIGDGELLPMEVYRQCMDVNFFGAVEVTKAF 192 Query: 369 YPLLNEN-ARVVNVSGPAGLL 428 PLL ++ RVVNVS AG + Sbjct: 193 MPLLRKSKGRVVNVSSLAGAM 213 >UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative - Rhizobium meliloti (Sinorhizobium meliloti) Length = 249 Score = 43.2 bits (97), Expect = 0.006 Identities = 36/139 (25%), Positives = 61/139 (43%), Gaps = 4/139 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 +ALV GA+S +G KL E K+ ++ K +E E ++MD+ Sbjct: 8 IALVTGASSGIGAATAAKLAEAG-AKVGIAARRTDKLEDLKKKIEAKGGEALVIEMDVVD 66 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNF--EKIRRTLSVNFYGYINFGKLVY 371 T S+ + D ID+L+N + ++ F ++ +R + VN G +N V Sbjct: 67 TTSVEAGVKKLVDAYGSIDILVNNAGLMPLSDIDQFKVDEWQRMVDVNVKGLLNTTAAVL 126 Query: 372 P--LLNENARVVNVSGPAG 422 P + + V N+S AG Sbjct: 127 PQMIKQHSGHVFNMSSIAG 145 >UniRef50_A5L8A4 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Vibrionales bacterium SWAT-3 Length = 287 Score = 43.2 bits (97), Expect = 0.006 Identities = 31/139 (22%), Positives = 58/139 (41%), Gaps = 4/139 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 V L+ GA S +G + + + ++Y + G + K + I+ + D+T Sbjct: 12 VVLITGANSGMGLETALLFAQKNY-RVYGSVRSIAKGLELEKVFAEKGLSITPVVCDVTR 70 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDY--VAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 371 T+ + + R+D+L+N Y VA E+ VN +G + + V Sbjct: 71 TQDVNDAIRMVMSDAGRLDILVNNAGYGLVASVEEGTDEEFMHQFDVNVFGVLRTCRAVI 130 Query: 372 PLLNE--NARVVNVSGPAG 422 P + E + ++NVS G Sbjct: 131 PFMREQNSGMIINVSSFLG 149 >UniRef50_A5K293 Cluster: Oxidoreductase, short-chain dehydrogenase family, putative; n=5; Plasmodium|Rep: Oxidoreductase, short-chain dehydrogenase family, putative - Plasmodium vivax Length = 395 Score = 43.2 bits (97), Expect = 0.006 Identities = 26/89 (29%), Positives = 47/89 (52%), Gaps = 1/89 (1%) Frame = +3 Query: 156 PDIEISYLQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVN 335 PD +I +Q+D+ KS+ I +ID+L+N +V++K L + RT +N Sbjct: 147 PDAKIHCVQLDLASYKSVESCASQILSKFPKIDILVNNAGFVSQK-LEYVNGLERTFFIN 205 Query: 336 FYGYINFGKLVYP-LLNENARVVNVSGPA 419 + G+ KL++ ++ + VVN+S A Sbjct: 206 YLGHFYLTKLLHKRIVASDTLVVNLSSIA 234 >UniRef50_Q1PLL0 Cluster: 17-beta hydroxysteroid dehydrogenase 2; n=3; Danio rerio|Rep: 17-beta hydroxysteroid dehydrogenase 2 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 358 Score = 42.7 bits (96), Expect = 0.008 Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 6/141 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 +A V S G+++ + L G F D LK E + ++ LQ+DIT Sbjct: 60 LAGVFSCDSGFGHELAQVLDRA--GMRVFAGVLDELSPGALKLKESASVNLTVLQLDITN 117 Query: 198 TKSIIRLRHYIQDLDERIDL--LIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGK 362 I + +I+ + L L+N + YV + + + + L VNF G + Sbjct: 118 NTQITQTHQFIKSQTGKTGLWALVNNAGVLGYVCDGEILPMKMYKSCLDVNFLGSVMMTH 177 Query: 363 LVYPLLNEN-ARVVNVSGPAG 422 PL+ ++ RV+N++ AG Sbjct: 178 TFLPLIRQSRGRVINITSMAG 198 >UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|Rep: CG4899-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 278 Score = 42.7 bits (96), Expect = 0.008 Identities = 35/140 (25%), Positives = 57/140 (40%), Gaps = 5/140 (3%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYT 200 A+V G A +G QV K+L K+ D + P + ++MD+ Sbjct: 25 AVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVANK 84 Query: 201 KSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPLL 380 K + I ID+++N+ + N + ++RTL VN G IN P + Sbjct: 85 KGVEATYEEIAKTFGNIDIVVNVA------GIFNDKDVQRTLLVNLGGIINSTLSALPYM 138 Query: 381 NEN-----ARVVNVSGPAGL 425 ++ VVN+S GL Sbjct: 139 GKDNGGKGGIVVNMSSVVGL 158 >UniRef50_UPI0000E47A47 Cluster: PREDICTED: similar to serum lectin P35; n=6; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to serum lectin P35 - Strongylocentrotus purpuratus Length = 740 Score = 42.3 bits (95), Expect = 0.010 Identities = 25/127 (19%), Positives = 56/127 (44%), Gaps = 2/127 (1%) Frame = +3 Query: 27 VVGAASNLGYQVLKKLTET--HKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYT 200 V G++S LG +++ L + G +Y T ++ G + L++ + + +D+ Sbjct: 580 VTGSSSGLGLAIVRSLCKRLGDDGIVYLTARNEGRGLEAVDVLKKEGLGPKFHILDVNDQ 639 Query: 201 KSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPLL 380 SI LR I +D+L+N + + + +T+ N++ N + P++ Sbjct: 640 DSIETLRDDIAAQHGGLDILVNNAGIIFNDDTPKAIQAEKTIQTNYFAVRNVTNALLPII 699 Query: 381 NENARVV 401 + +V Sbjct: 700 RDGGSLV 706 >UniRef50_UPI000038DA04 Cluster: COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); n=1; Nostoc punctiforme PCC 73102|Rep: COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - Nostoc punctiforme PCC 73102 Length = 267 Score = 42.3 bits (95), Expect = 0.010 Identities = 37/141 (26%), Positives = 63/141 (44%), Gaps = 4/141 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 V LV GA+S G KKL G F T + + D+E+ L++D+T Sbjct: 6 VVLVTGASSGFGQLTAKKLAAV--GYWVFGTSRKSYPAS-------GDVEM--LKLDVTS 54 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNL--SNFEKIRRTLSVNFYGYINFGKLVY 371 S+ + RIDLLIN + L ++ ++ + NF+G + V Sbjct: 55 DSSVQLCIKQLLTRTNRIDLLINNAGQIHASMLEETSLQQAKEIFETNFWGVVRLTNAVL 114 Query: 372 PLLNE--NARVVNVSGPAGLL 428 P++ + + ++N+S AGL+ Sbjct: 115 PVMRQQRSGHIINISSVAGLI 135 >UniRef50_Q8XAM8 Cluster: Putative fatty acyl chain reductase; n=2; Escherichia coli O157:H7|Rep: Putative fatty acyl chain reductase - Escherichia coli O157:H7 Length = 251 Score = 42.3 bits (95), Expect = 0.010 Identities = 31/142 (21%), Positives = 64/142 (45%), Gaps = 4/142 (2%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 203 LV GA+ ++G + +K E + +Y + + LK+ ++ +Q D+ + Sbjct: 13 LVTGASGDIGLGICEKYLEQNCD-VYALYKSNDVQLTALKASHPAGDKLHIVQCDLACPQ 71 Query: 204 SIIRLRHYIQDLDERIDLLINITDYVAEKNLS--NFEKIRRTLSVNFYGYINFGKLVYPL 377 S+ L I+ +ID+L+N V + + ++E + + N + K L Sbjct: 72 SVSALCEQIERQAGKIDVLVNNAGIVKDSLFASMSYEDFTQVIETNMFSIFRLTKDALML 131 Query: 378 LN--ENARVVNVSGPAGLLATI 437 L EN ++NV+ A L+ ++ Sbjct: 132 LRAAENPAIINVASIAALIPSV 153 >UniRef50_Q5KW73 Cluster: 3-ketoacyl-[acyl carrier protein] reductase; n=1; Geobacillus kaustophilus|Rep: 3-ketoacyl-[acyl carrier protein] reductase - Geobacillus kaustophilus Length = 280 Score = 42.3 bits (95), Expect = 0.010 Identities = 28/89 (31%), Positives = 46/89 (51%), Gaps = 5/89 (5%) Frame = +3 Query: 177 LQMDITYTKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGY 347 L+MD+T + + + +++ ID+L+N D+V++ N E R L VN G Sbjct: 89 LKMDVTDREQVKEVFARVKEEFGSIDILVNNAGTLDHVSQIEKQNDEFWERDLRVNLTGT 148 Query: 348 INFGKLVYPLLNEN--ARVVNVSGPAGLL 428 N K V+P + E R++N+S AG L Sbjct: 149 YNCTKAVWPYMKEQGWGRIINMSSVAGTL 177 >UniRef50_Q3JV89 Cluster: Putative uncharacterized protein; n=6; Burkholderia|Rep: Putative uncharacterized protein - Burkholderia pseudomallei (strain 1710b) Length = 683 Score = 42.3 bits (95), Expect = 0.010 Identities = 53/196 (27%), Positives = 81/196 (41%), Gaps = 9/196 (4%) Frame = +2 Query: 17 RSAGRRRRKQPRIPSLKKTHRDSQRKNLLHYRR*HSRLQHPQEPGEARHRNQLLANGHHV 196 R RRRRK R+ + +R + ++L + RR H RL+H + P + RHR H Sbjct: 377 RRLKRRRRKHRRLKHRRPKYRHRKHRHLKYRRRKHRRLKH-RRP-KYRHRK-------HC 427 Query: 197 YKEHHQTEALHPGSRRKDRFADKHHRLCGREEFI*FRKNPKNFER*LLRIHKL---WEAC 367 ++H + + HP R R +H + +P F R + + W C Sbjct: 428 RRKHRRRKHRHPKPRHWKRRLPQHRAPKCHD----LTHHPPTFRRPMRCLPSCRVRWPPC 483 Query: 368 VPATERER*SRKRVWTSWSSSHNRKRRYKKENQRSHIDRR*TGRFDPRIRTR-----RKK 532 P + R+ W H+R+ R + R RR RF PR+R R R++ Sbjct: 484 RPRSSLLSHRRQSPQRRW--HHSRRLRRRCFRGRCPRCRR-RFRFRPRLRPRHSPPCRRR 540 Query: 533 G-SREDRRLGHECACR 577 G +R R G A R Sbjct: 541 GAARRRTRPGRSRAAR 556 Score = 34.7 bits (76), Expect = 2.0 Identities = 47/182 (25%), Positives = 70/182 (38%), Gaps = 5/182 (2%) Frame = +2 Query: 32 RRRKQPRIPSLKKTHRDSQRKNLLHYRR*HSRLQHPQEPGEAR-HRNQLLANGHHVYKEH 208 RRRK R + HR + + L H R RL+H + R HR + + H +++ Sbjct: 212 RRRKYRRPKYRHRKHRHRKHRRLKHRRPKRRRLKHRRLKHRCRKHRCRKHRHRKHRHRKR 271 Query: 209 HQTEALHPGSRRKDRFADKHHRLCGREEFI*FRKNPKNFER*LLRIHKLWEACVP--ATE 382 + + P RR KH R RK R R H+ + P Sbjct: 272 RRPKYRRPKCRRLKHRHRKHRHRKHRHRKHRHRKRRHRKRR--RRKHRRLKHRRPKYRHR 329 Query: 383 RER*SRKRVWTSWSSSHNR-KRRYKKENQRSHIDRR*TGRFDPRIRTRR-KKGSREDRRL 556 + R + R H R KRR +K + H + R ++ RR K+ R+ RRL Sbjct: 330 KHRHRKHRHRKRRRLKHCRLKRRRRKHRRLKHRRPKYRHRKHRHLKYRRLKRRRRKHRRL 389 Query: 557 GH 562 H Sbjct: 390 KH 391 Score = 32.7 bits (71), Expect = 8.0 Identities = 39/169 (23%), Positives = 65/169 (38%), Gaps = 2/169 (1%) Frame = +2 Query: 32 RRRKQPRIPSLKKTHRDSQRKNLLHYRR*HSRLQHPQEPGEARHRNQLLAN--GHHVYKE 205 R RK ++ +R + ++ H R H RL+H + P R +++ L + H ++ Sbjct: 202 RHRKDRHRKYRRRKYRRPKYRHRKHRHRKHRRLKH-RRPKRRRLKHRRLKHRCRKHRCRK 260 Query: 206 HHQTEALHPGSRRKDRFADKHHRLCGREEFI*FRKNPKNFER*LLRIHKLWEACVPATER 385 H + H RR K RL R RK+ R R H+ + Sbjct: 261 HRHRKHRHRKRRRPKYRRPKCRRLKHRHRKHRHRKHRHRKHRHRKRRHRKRR----RRKH 316 Query: 386 ER*SRKRVWTSWSSSHNRKRRYKKENQRSHIDRR*TGRFDPRIRTRRKK 532 R +R +RK R++K + H + R R++ RR K Sbjct: 317 RRLKHRRPKYRHRKHRHRKHRHRKRRRLKHCRLKRRRRKHRRLKHRRPK 365 Score = 32.7 bits (71), Expect = 8.0 Identities = 29/100 (29%), Positives = 41/100 (41%) Frame = +2 Query: 14 QRSAGRRRRKQPRIPSLKKTHRDSQRKNLLHYRR*HSRLQHPQEPGEARHRNQLLANGHH 193 +R RRRRK R+ + +R + ++ H R RL+H + R +L H Sbjct: 306 RRHRKRRRRKHRRLKHRRPKYRHRKHRHRKHRHRKRRRLKHCRLKRRRRKHRRL---KHR 362 Query: 194 VYKEHHQTEALHPGSRRKDRFADKHHRLCGREEFI*FRKN 313 K H+ H RR R KH RL R RK+ Sbjct: 363 RPKYRHRKHR-HLKYRRLKRRRRKHRRLKHRRPKYRHRKH 401 >UniRef50_Q2JGQ2 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. (strain CcI3) Length = 244 Score = 42.3 bits (95), Expect = 0.010 Identities = 33/151 (21%), Positives = 62/151 (41%), Gaps = 8/151 (5%) Frame = +3 Query: 15 NVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDIT 194 + ALV G+ LG+ + L ++ T + A L + + +D+T Sbjct: 2 SAALVTGSNRGLGFATAQALARLGH-RVLVTAREQAAADKAAADLTAQGFDADAIALDVT 60 Query: 195 YTKSIIRLRHYIQDLDERIDLLINITDYVAE------KNLSNFEKIRRTLSVNFYGYINF 356 SI + +L +D+L+N + E ++ + +T + N +G + Sbjct: 61 SPDSIAAATRRVAELPAGLDILVNNAGILPEATDGEQHEFASLDLFGKTYATNVFGPVAV 120 Query: 357 GKLVYPLLNEN--ARVVNVSGPAGLLATIEN 443 + + PLL + R+VNVS G L+ N Sbjct: 121 TEALLPLLRRSPAGRIVNVSTTMGSLSDQAN 151 >UniRef50_A7DM41 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Methylobacterium extorquens PA1|Rep: Short-chain dehydrogenase/reductase SDR - Methylobacterium extorquens PA1 Length = 271 Score = 42.3 bits (95), Expect = 0.010 Identities = 38/141 (26%), Positives = 64/141 (45%), Gaps = 4/141 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VA+V GAAS +G + + L +++ T+ K + + +I+ L D+T Sbjct: 8 VAIVTGAASGIGLETARALKAAGY-RVFGTSR---------KVDQVVEGDITMLPCDLTS 57 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNL--SNFEKIRRTLSVNFYGYINFGKLVY 371 S+ + I RIDLL+N + S+ E+ + VN +G I + V Sbjct: 58 DASVAGVVETISSRTGRIDLLVNNAGFGISGGAEESSIEQAQALFDVNLFGAIRMTRAVL 117 Query: 372 PLLNE--NARVVNVSGPAGLL 428 PL+ R+VN+S GL+ Sbjct: 118 PLMRAGGGGRIVNISSLFGLV 138 >UniRef50_A6LY80 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Clostridium beijerinckii NCIMB 8052|Rep: Short-chain dehydrogenase/reductase SDR - Clostridium beijerinckii NCIMB 8052 Length = 239 Score = 42.3 bits (95), Expect = 0.010 Identities = 35/138 (25%), Positives = 70/138 (50%), Gaps = 6/138 (4%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYT 200 ALV G+ +G+++ KKL + + D++ G N + L + + +++D + + Sbjct: 4 ALVTGSNKGIGFEISKKLLK-EGYHVLVGARDESRGKNAITELAKYG-PVDLIKIDYSDS 61 Query: 201 KSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNF--EKIRRTLSVNFYGYINFGKL 365 +SI + + + ++LL+N I + ++ F E++ T +V+F G K Sbjct: 62 ESIKEAVKRVSNEYKELNLLVNNAGIPGPLIKRPSWEFTKEELLETYTVDFLGPFELSKG 121 Query: 366 VYPLLNEN-ARVVNVSGP 416 + P+L EN ++VNVS P Sbjct: 122 LLPILIENHGKIVNVSIP 139 >UniRef50_A4CX59 Cluster: Short-chain dehydrogenase/reductase (SDR) superfamily protein; n=7; Bacteria|Rep: Short-chain dehydrogenase/reductase (SDR) superfamily protein - Synechococcus sp. (strain WH7805) Length = 306 Score = 42.3 bits (95), Expect = 0.010 Identities = 37/153 (24%), Positives = 62/153 (40%), Gaps = 2/153 (1%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQ 182 D VALV GA S LG + + L + LE + + Sbjct: 10 DQQGRVALVTGANSGLGLETTRALIGRGCTVLMGCRSARKGEAARALLLEAGGSGLDLFE 69 Query: 183 MDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGK 362 +D++ S+ R + D R+DLLIN +A + + + +VN G+ + Sbjct: 70 LDLSDLTSVARCARDVADRYGRLDLLINNAGLMAPPRMLSQQGHEMQFAVNHLGHFALTQ 129 Query: 363 LVYPLLNE--NARVVNVSGPAGLLATIENEDIR 455 + PL+N ARVV V+ A + +D++ Sbjct: 130 ALLPLMNNRPQARVVTVTSGAQYFGAMAWDDLQ 162 >UniRef50_Q9L2C8 Cluster: Putative oxidoreductase; n=1; Streptomyces coelicolor|Rep: Putative oxidoreductase - Streptomyces coelicolor Length = 310 Score = 41.9 bits (94), Expect = 0.013 Identities = 36/149 (24%), Positives = 64/149 (42%), Gaps = 4/149 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSL-ERPDIEISYLQMDIT 194 VA+V GA LGY + ++L + ++ + + + E P + ++D+ Sbjct: 16 VAVVTGANGGLGYVIARELARKGATVVLACRSEERGSAAVRRLMGEVPAAAVEPARLDLG 75 Query: 195 YTKSIIRLRHYIQDLD-ERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 371 S+ R + L ER+DLL+N +A + + + VN G+ L+ Sbjct: 76 DLASV---REFAYGLPYERVDLLVNNAGVMALPHGTTVDGFETQFGVNHLGHFALTGLLL 132 Query: 372 P--LLNENARVVNVSGPAGLLATIENEDI 452 P L AR+V VS LA ++ D+ Sbjct: 133 PSLLAAPGARIVTVSSVLHALARVDPRDL 161 >UniRef50_Q1V1U2 Cluster: FabG-like protein; n=2; Candidatus Pelagibacter ubique|Rep: FabG-like protein - Candidatus Pelagibacter ubique HTCC1002 Length = 259 Score = 41.9 bits (94), Expect = 0.013 Identities = 34/144 (23%), Positives = 67/144 (46%), Gaps = 4/144 (2%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQ 182 D ALV G A+ LG + L ++ K+ T+ + +I K + P I Sbjct: 4 DLKRKTALVTGGATGLGKGIAIALANSN-AKVVVTSRNKK---DIEKISKHPSGNIFGYN 59 Query: 183 MDITYTKSIIRLRHYIQDLDERIDLLINITDYVAE--KNLSNFEKIRRTLSVNFYGYINF 356 +DIT + + L I+ ++ID+LIN + + +N ++ + +NF+ +N Sbjct: 60 LDITNSSELETLYKNIKKKYQKIDILINNVGHTLDIKDPFTNINNWKKVMDLNFFTAVNV 119 Query: 357 GKL-VYPLLNEN-ARVVNVSGPAG 422 + + + +N R++N++ AG Sbjct: 120 NNMFINDMKKKNWGRIINITSIAG 143 >UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reductase; n=1; Bacillus sp. SG-1|Rep: 3-oxoacyl-(Acyl-carrier-protein) reductase - Bacillus sp. SG-1 Length = 246 Score = 41.9 bits (94), Expect = 0.013 Identities = 30/143 (20%), Positives = 64/143 (44%), Gaps = 4/143 (2%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYT 200 A++ G+A+ +G KK + K+ D+ G + L+ + + Q+D+ Sbjct: 8 AVITGSANGIGLAAAKKFAQ-EGCKVIMADYDENKGAAEAEKLQEEGGDTVFYQVDVANR 66 Query: 201 KSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNF--EKIRRTLSVNFYGYINFGKLVYP 374 +S+ L ++ ID+LIN + ++ + +R L VN G + + + P Sbjct: 67 ESVDNLAAWVLRDYGSIDILINNAGITRDALMAKMREDDFQRVLDVNLTGVFHCTQALLP 126 Query: 375 -LLNE-NARVVNVSGPAGLLATI 437 L+N +++N + +GL + Sbjct: 127 ALINSGKGKIINTASASGLYGNV 149 >UniRef50_Q5CAF5 Cluster: Neomenthol dehydrogenase; n=5; core eudicotyledons|Rep: Neomenthol dehydrogenase - Mentha piperita (Peppermint) Length = 324 Score = 41.9 bits (94), Expect = 0.013 Identities = 30/110 (27%), Positives = 52/110 (47%), Gaps = 6/110 (5%) Frame = +3 Query: 294 LSNFEKIRRTLSVNFYGYINFGKLVYPLL--NENARVVNVSGPAGLLATIENEDIRKRIS 467 + E + + N+YG + + PLL + + R+VNVS G L NE + S Sbjct: 150 VETLESAKECIETNYYGAKRITQALIPLLQLSRSPRIVNVSSSLGSLVLHPNEWAKGVFS 209 Query: 468 --DPTLTEDELVALIQEYEHAARRGVEKTEGWGMN--VHAVSKVALNAVT 605 D +LTE+++ ++ E+ + + W + + VSK A+NA T Sbjct: 210 SEDNSLTEEKVEEVLHEFLKDFKEAKLQENHWPHHFAAYKVSKAAMNAYT 259 >UniRef50_A6SHG0 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 266 Score = 41.9 bits (94), Expect = 0.013 Identities = 29/132 (21%), Positives = 53/132 (40%), Gaps = 2/132 (1%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLER--PDIEISY 176 D V LV G LG++ + +L++ + IY + +K ++ P I++ Sbjct: 21 DLSGKVILVTGGNVGLGFETILQLSKHNPSHIYLAARSEPKATAAIKEIQSKVPSAPITF 80 Query: 177 LQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINF 356 +Q D+T S+ + R+DLL +A + + N G+ Sbjct: 81 IQCDLTSLPSVQECAKQFNAKESRLDLLFLNAGIMAVPAATTEQGYEVQFGTNHVGHALL 140 Query: 357 GKLVYPLLNENA 392 KL+ P L + A Sbjct: 141 TKLLLPTLLKTA 152 >UniRef50_A6R5Y9 Cluster: Predicted protein; n=1; Ajellomyces capsulatus NAm1|Rep: Predicted protein - Ajellomyces capsulatus NAm1 Length = 402 Score = 41.9 bits (94), Expect = 0.013 Identities = 36/138 (26%), Positives = 60/138 (43%), Gaps = 7/138 (5%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDD----TAGFNILKSLERPDI-- 164 D V LV G S LG Q +L + + +IY + TA +I SL I Sbjct: 109 DLSGKVILVTGGNSGLGKQTALQLAKHYPSRIYLGARTESKALTAIEDIKSSLTTEQIST 168 Query: 165 -EISYLQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFY 341 +I YL +D++ +SI + + R+D+L+ +A + + NF Sbjct: 169 TDIRYLPLDLSSFQSIRNAASIFRSENNRLDILMLNAGVMAVPPGTTEDGYEIQFGTNFL 228 Query: 342 GYINFGKLVYPLLNENAR 395 G+ KL+ P+L + A+ Sbjct: 229 GHFLLTKLLLPILIQTAK 246 >UniRef50_Q8TP33 Cluster: Short chain dehydrogenase; n=1; Methanosarcina acetivorans|Rep: Short chain dehydrogenase - Methanosarcina acetivorans Length = 245 Score = 41.9 bits (94), Expect = 0.013 Identities = 27/94 (28%), Positives = 50/94 (53%), Gaps = 5/94 (5%) Frame = +3 Query: 177 LQMDITYTKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGY 347 +Q DI+ K ++R+R I++ +D+LIN Y + LSN +++R+ VNF+G Sbjct: 60 IQCDISSEKEVLRMRSIIENNFTCVDVLINNAGFGTYEVSEKLSN-QEMRKHFEVNFFGA 118 Query: 348 INFGKLVYPLLNEN--ARVVNVSGPAGLLATIEN 443 K + PL+ ++ ++NV ++ EN Sbjct: 119 YYCTKALLPLIKKSDCGYILNVGSLFSKISLAEN 152 >UniRef50_UPI00015B6097 Cluster: PREDICTED: similar to CG11200-PA; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to CG11200-PA - Nasonia vitripennis Length = 350 Score = 41.5 bits (93), Expect = 0.017 Identities = 34/157 (21%), Positives = 72/157 (45%), Gaps = 9/157 (5%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDI---EISYLQMD 188 VA+V G + +G +V++ L ++ ++ +AG ++S+ + + + + +++D Sbjct: 67 VAIVTGGSRGIGTEVVRMLLQSDV-EVVIACRRTSAGEKAVESIRKCGVTSGKANVMELD 125 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 + S+ + ++ +++D+L+N + + VN+ + L+ Sbjct: 126 NSSLDSVRKFVEEFKNNYQKLDILVNNAGIMFTPYGETKDGFEEQYGVNYLSHFLLTVLL 185 Query: 369 YPLLNEN------ARVVNVSGPAGLLATIENEDIRKR 461 PLL ARVVNVS A LL I ED+ + Sbjct: 186 IPLLKNAGTADCFARVVNVSSCAHLLGDINFEDVNHK 222 >UniRef50_A4XSH7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Pseudomonas mendocina ymp Length = 328 Score = 41.5 bits (93), Expect = 0.017 Identities = 49/211 (23%), Positives = 95/211 (45%), Gaps = 9/211 (4%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLER--PDIEISYLQMDITY 197 LV G +S +G++ L+ ++ + G ++ + P ++ + Q+D+ Sbjct: 41 LVTGGSSGMGFEDALALSRAG-AQVIIAARNSQRGAESIERIRAQVPQAQLRFEQLDLAD 99 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVA--EKNLSNFEKIRRTLSVNFYGYINFGKLVY 371 S+ L + E +D+LIN +A ++ +S + L+ NF G+ L+ Sbjct: 100 LASVRSLAQRLNAEGEVLDVLINNAAIMAPPQRGVSR-DGFEMQLATNFLGHFALTGLLL 158 Query: 372 PLLNENA--RVVNVSGPAGLLATIENEDIR-KRISDP--TLTEDELVALIQEYEHAARRG 536 L +++ RVV ++ A I+ +D++ +R DP + +L L+ +E RR Sbjct: 159 SSLRKSSDPRVVTLASIAVNRGRIDFDDLQSERSYDPYAAYAQSKLACLMMAFE-LQRRS 217 Query: 537 VEKTEGWGMNVHAVSKVALNAVTFLQHRGMG 629 + WG V +++ AVT L RG G Sbjct: 218 L--ANNWG--VRSIAAHPGVAVTELVERGPG 244 >UniRef50_A7F9T5 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 190 Score = 41.5 bits (93), Expect = 0.017 Identities = 29/141 (20%), Positives = 69/141 (48%), Gaps = 6/141 (4%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTED----DTAGFNILKSLERPDIE- 167 D VA++ G + +GY L + + K++ D A +I K++ + Sbjct: 32 DQSGKVAVITGGSEGIGYGCAHTLLKNNLTKLFIIAVSQEVYDDAVEDISKTISPEAAQR 91 Query: 168 ISYLQMDITYTKSIIRLRHYIQDLDERIDLLINITDY-VAEKNLSNFEKIRRTLSVNFYG 344 ++LQ D++ ++ ++ H I + +R+D+L N+ + L+++ + R ++VN +G Sbjct: 92 CTFLQCDMSDWPAVSKVAHTISEGTDRVDILCNLAARGIMTYQLTDY-GLDRHMAVNHFG 150 Query: 345 YINFGKLVYPLLNENARVVNV 407 ++ + P+L + A ++ Sbjct: 151 HVVLTSHLLPILKQTAEAGHI 171 >UniRef50_Q2NGE1 Cluster: Predicted short chain dehydrogenase; n=4; cellular organisms|Rep: Predicted short chain dehydrogenase - Methanosphaera stadtmanae (strain DSM 3091) Length = 253 Score = 41.5 bits (93), Expect = 0.017 Identities = 35/146 (23%), Positives = 58/146 (39%), Gaps = 5/146 (3%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQ 182 D V +V G +G+ + + K I T ++ + + LE+ +E+ + Sbjct: 4 DMKGKVTIVTGGGKGIGFGIATAFAKA-KSNIVITGRTESTLISAKEKLEKYGVEVLPIT 62 Query: 183 MDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRR----TLSVNFYGYI 350 D Y + + I + RID+LIN ++ L E + + Y Sbjct: 63 ADGGYEEQVKEAVDKIIEKFGRIDVLIN-NAQASKSGLQLVEHTQEDFDLAIKSGIYAVF 121 Query: 351 NFGKLVYPLLNE-NARVVNVSGPAGL 425 NF K YP L E V+N + AGL Sbjct: 122 NFMKFTYPYLKETKGSVINFASGAGL 147 >UniRef50_Q53217 Cluster: Uncharacterized short-chain type dehydrogenase/reductase y4vI; n=5; Proteobacteria|Rep: Uncharacterized short-chain type dehydrogenase/reductase y4vI - Rhizobium sp. (strain NGR234) Length = 548 Score = 41.5 bits (93), Expect = 0.017 Identities = 34/140 (24%), Positives = 65/140 (46%), Gaps = 3/140 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 V +V GAA +G + L + + + D+ + ++L P + L++D++ Sbjct: 11 VIVVTGAAGGIG-RALVDIFAANGDVVVAVDLPDSGVIELGQNLGEPHLG---LEVDVSR 66 Query: 198 TKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 ++ LR ++ RI++L+N I +A + E +R L++N G + Sbjct: 67 EDDVVALRALLEKRFSRIEVLVNNAGIGPTMAATADTALEDFQRALAINLVGAYSVACET 126 Query: 369 YPLLNENARVVNVSGPAGLL 428 L+ A +VNV+ AGLL Sbjct: 127 AKLMKPGAAIVNVASLAGLL 146 >UniRef50_Q5NZV3 Cluster: (S)-1-Phenylethanol dehydrogenase; n=4; Bacteria|Rep: (S)-1-Phenylethanol dehydrogenase - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 249 Score = 41.1 bits (92), Expect = 0.023 Identities = 32/135 (23%), Positives = 60/135 (44%), Gaps = 4/135 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VA+V GAA+ +G L + D T +K+L+ + + QMD+ Sbjct: 9 VAIVTGAAAGIGRTFCVGLAGEGARVVAADLRDVTETLAEIKALDGTAMGV---QMDVAN 65 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLS--NFEKIRRTLSVNFYGYINFGKLVY 371 + + R+ + D+ R+D+L+N + + E RR ++N G K V Sbjct: 66 PEDVARMVKQVTDIYGRVDILVNNAGIYPTSPIEQISLEDWRRVTAINLDGPFLCSKAVV 125 Query: 372 PL--LNENARVVNVS 410 P+ L + R++N++ Sbjct: 126 PIMKLQRHGRIINMT 140 >UniRef50_Q1N3U9 Cluster: Short chain dehydrogenase; n=1; Oceanobacter sp. RED65|Rep: Short chain dehydrogenase - Oceanobacter sp. RED65 Length = 278 Score = 41.1 bits (92), Expect = 0.023 Identities = 35/145 (24%), Positives = 67/145 (46%), Gaps = 7/145 (4%) Frame = +3 Query: 15 NVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIE---ISYLQM 185 N L+ GAA G + L+ H+G ++ DT G + ++ E D+ ++Q Sbjct: 8 NRVLITGAAKGFGRALA--LSFAHRGWRILLSDIDTEG--LAETAELVDLAGGMAHWVQC 63 Query: 186 DITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIR--RTLSVNFYGYINFG 359 DIT + + R+ +L + +D+LIN A ++ + + L N G I Sbjct: 64 DITQPEQVTRMYDTAMELWQGVDVLINNAGIYAGGRFADIPESNWSKVLDTNLIGTIRCC 123 Query: 360 KLVYPLLNE--NARVVNVSGPAGLL 428 + P+ + + R+VN++ +G+L Sbjct: 124 QKFVPMFQKQRSGRIVNIASLSGIL 148 >UniRef50_A0PND0 Cluster: Oxidoreductase; n=4; Actinomycetales|Rep: Oxidoreductase - Mycobacterium ulcerans (strain Agy99) Length = 317 Score = 41.1 bits (92), Expect = 0.023 Identities = 44/198 (22%), Positives = 82/198 (41%), Gaps = 7/198 (3%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLER--PDIEISY 176 D +A+V GA S LG+ + ++L+ + + G ++ + PD ++S Sbjct: 11 DLSGKLAIVTGANSGLGFGLARRLSAAG-ADVVMAIRNRAKGEAAIEEIRSAVPDAKLST 69 Query: 177 LQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVA-EKNLSNFEKIRRTLSVNFYGYIN 353 +D++ S+ L + ID+LIN + + + + N G+ Sbjct: 70 KALDLSSLASVAALGDQLNSEGRPIDILINNAGVMTPPERDTTADGFELQFGSNHLGHFA 129 Query: 354 FGKLVYPLLN--ENARVVNVSGPAGLLATIENEDIR--KRISDPTLTEDELVALIQEYEH 521 V PLL + ARVV++S A I +D++ K + T +A++ Sbjct: 130 LTAHVLPLLRAAQGARVVSLSSLAARRGRIHFDDLQFEKSYAAMTAYGQSKLAVLMFARE 189 Query: 522 AARRGVEKTEGWGMNVHA 575 RR + GWG+ +A Sbjct: 190 LDRR--SRAAGWGVMSNA 205 >UniRef50_A4QXZ6 Cluster: Putative uncharacterized protein; n=3; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 321 Score = 41.1 bits (92), Expect = 0.023 Identities = 32/141 (22%), Positives = 58/141 (41%), Gaps = 10/141 (7%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERP---DIEISYLQMD 188 +A V G LG + + +L + +I+ ++ +K + ++++MD Sbjct: 22 IAFVTGGNGGLGLETVIQLAKAGMERIFIGARNEEKALKAIKEISTNLNCSTTFTFVKMD 81 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 +T S+ R + +++ LLIN V E N G+ F +L+ Sbjct: 82 LTSFDSVCRAADQVISQTDKLHLLINNAGVVGTAPGLTPEGYETQWGTNHMGHALFTRLL 141 Query: 369 YPLLNENA-------RVVNVS 410 PLL + A R+VNVS Sbjct: 142 LPLLKQTAEGGRVDVRIVNVS 162 >UniRef50_UPI0000E47390 Cluster: PREDICTED: similar to retinol dehydrogenase 8 (all-trans), partial; n=4; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to retinol dehydrogenase 8 (all-trans), partial - Strongylocentrotus purpuratus Length = 216 Score = 40.7 bits (91), Expect = 0.030 Identities = 30/145 (20%), Positives = 64/145 (44%), Gaps = 7/145 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGK--IYFTTEDDTAGFNILKSL-ERPDIEISYLQMD 188 V L+ G ++ +G + +L + K +Y T + + K+ + D + Q+D Sbjct: 5 VVLISGCSTGIGLALAARLAQDPDKKYLVYATMRNLAKKEGLEKATGDALDKTLFVRQLD 64 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINIT--DYVAEKNLSNFEKIRRTLSVNFYGYINFGK 362 +T + + +I R+D+L+N + + EK + N++G + + Sbjct: 65 VTVDDQVKSIFEFIMGKHGRVDVLVNNAGFGFFGPLEAMSMEKAKSMFDTNYFGTVRLIR 124 Query: 363 LVYPLL--NENARVVNVSGPAGLLA 431 P++ ++ R+VN+S G LA Sbjct: 125 AALPIMKKQKSGRIVNISSILGHLA 149 >UniRef50_A4WBV5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Enterobacter sp. 638|Rep: Short-chain dehydrogenase/reductase SDR - Enterobacter sp. 638 Length = 248 Score = 40.7 bits (91), Expect = 0.030 Identities = 29/140 (20%), Positives = 61/140 (43%), Gaps = 5/140 (3%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSL-ERPDIEISYLQMDITY 197 A+V G +G L ++D A + L E + I+ + D+ Sbjct: 8 AVVTGCLQGIGKATLVAFARQGANLFACVQQEDEAFLTFISDLSEEHGVSITPVSFDLLD 67 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEK--NLSNFEKIRRTLSVNFYGYINFGKLVY 371 SI + IQ + ID+L+N+ + + ++++T ++NF+ + F + + Sbjct: 68 DASIKQAAMTIQKAKQPIDILVNVAGITLDALFPMVTLAQMQKTFTINFFSQMVFTQYMT 127 Query: 372 PLLNENAR--VVNVSGPAGL 425 L+ N R ++N++ +GL Sbjct: 128 RLMLRNKRGSIINIASISGL 147 >UniRef50_A3D6S9 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Shewanella baltica OS155|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella baltica OS155 Length = 251 Score = 40.7 bits (91), Expect = 0.030 Identities = 34/139 (24%), Positives = 58/139 (41%), Gaps = 4/139 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VAL+ GA+ +G + + I +D A F ++ L+ ++ ++ D++ Sbjct: 8 VALITGASRGIGAGIAEAFAIEGADLIINYRTNDDAAFRVVSKLKNLGRKVVAIRADVSK 67 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEK--NLSNFEKIRRTLSVNFYGYINFGKLVY 371 I L H Q RID+L+N N E + N G + V+ Sbjct: 68 RSEIQNLIHLAQIEFGRIDILVNNAGINQRGWFNEVTDEAWDMIMGTNLKGPFMCCQEVF 127 Query: 372 PLLNEN--ARVVNVSGPAG 422 PL+ N R++N+S AG Sbjct: 128 PLMKANGGGRIINISSVAG 146 >UniRef50_A3CQN6 Cluster: Dehydrogenase, eukaryotic-like, putative; n=3; Lactobacillales|Rep: Dehydrogenase, eukaryotic-like, putative - Streptococcus sanguinis (strain SK36) Length = 284 Score = 40.7 bits (91), Expect = 0.030 Identities = 34/136 (25%), Positives = 64/136 (47%), Gaps = 7/136 (5%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERP-DIEISYLQMDITYT 200 ++ G S +GYQ K+L E F + A K ++ + + Y+ +D++ Sbjct: 5 IITGGNSGIGYQAAKQLAEKGWSVTLFCRRKEAAEQACEKIRQQTGNSHVDYILVDLSEM 64 Query: 201 KSIIR-LRHYIQDLDERIDLLINIT---DYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 KS+ + + YIQ +E +D+LIN D +K + + + + + N L+ Sbjct: 65 KSVRKAVEQYIQK-EETLDVLINNAADFDLSIKKPILTKDGLEKQFATNVVAPFLLSALL 123 Query: 369 YPLL--NENARVVNVS 410 LL +E+ R+VN+S Sbjct: 124 KGLLEKSESGRIVNIS 139 >UniRef50_A4RF95 Cluster: Putative uncharacterized protein; n=1; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 297 Score = 40.7 bits (91), Expect = 0.030 Identities = 31/139 (22%), Positives = 65/139 (46%), Gaps = 9/139 (6%) Frame = +3 Query: 48 LGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPD--IEISYLQMDITYTKSIIRLR 221 +G ++++ L +T +++FT D G + + L D ++ + +++ KS+ Sbjct: 1 MGLELVRTLAKTGM-RVFFTARDPAKGAKVREMLRAEDASFKLELVVVELKSLKSVEAGA 59 Query: 222 HYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPLLNENA--- 392 +I D +R+DLL+N A + + + VN+ + +++ PLL + A Sbjct: 60 RHILDRADRLDLLMNNAGIAATPHGFTQDGYEQQFGVNYLAHFYLFQMLKPLLLKTAAEH 119 Query: 393 ----RVVNVSGPAGLLATI 437 RVV+ S A +T+ Sbjct: 120 GVQVRVVSTSSTAHTASTV 138 >UniRef50_Q1VNC3 Cluster: Predicted short-chain dehydrogenase; n=1; Psychroflexus torquis ATCC 700755|Rep: Predicted short-chain dehydrogenase - Psychroflexus torquis ATCC 700755 Length = 268 Score = 40.3 bits (90), Expect = 0.040 Identities = 31/141 (21%), Positives = 70/141 (49%), Gaps = 5/141 (3%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLE-RPDIEISYLQMDITY 197 ALV G++S +G++++K L+ +I T + + + +E + ++ L D+ Sbjct: 9 ALVTGSSSGIGFEIVKYLSRFDM-QIIITARREDKLLKLKEEVESNSNSKVIVLVKDLAK 67 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNF--EKIRRTLSVNFYGYINFGKLVY 371 ++S + Y Q+ + +ID L+N Y ++ ++ EK+ L+V + +L Sbjct: 68 SESPQEIYDYCQNNNYKIDFLVNNAGYGFTEDFDSYDLEKLDDFLNVLLNSLVKLTRLFI 127 Query: 372 PLLNE--NARVVNVSGPAGLL 428 + E + +++ VS AG++ Sbjct: 128 KDMKEKKSGKILQVSSIAGII 148 >UniRef50_Q15W58 Cluster: Short-chain dehydrogenase/reductase SDR; n=14; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 270 Score = 40.3 bits (90), Expect = 0.040 Identities = 43/157 (27%), Positives = 65/157 (41%), Gaps = 9/157 (5%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKL-----TETHKGKIYFTTEDDTAGFNILKSLERPDIEIS 173 M LV GA +G++ K L T G+ +D A L S D Sbjct: 1 MSKTVLVTGATDGIGFETAKMLLSAGHTVLLHGRNNRKLQDAQAA---LTSATGSDKTEC 57 Query: 174 YLQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYIN 353 YL D++ +I+L I++ + +D LIN ++ +++ VN Sbjct: 58 YLA-DLSDVSQVIQLADAIKEKHKVLDALINNAGVFKVPSVITADELDVRFVVNTIAPYV 116 Query: 354 FGKLVYPLLNENARVVNVS----GPAGLLATIENEDI 452 K + P+L +NARVVNVS P L A N+ I Sbjct: 117 LTKALLPILAKNARVVNVSSAAQAPVSLAALAGNQSI 153 >UniRef50_Q7YWE8 Cluster: Normocyte binding protein 2b; n=19; Plasmodium (Laverania)|Rep: Normocyte binding protein 2b - Plasmodium falciparum Length = 3256 Score = 40.3 bits (90), Expect = 0.040 Identities = 24/64 (37%), Positives = 38/64 (59%), Gaps = 5/64 (7%) Frame = +3 Query: 168 ISYLQMDITYTKSIIRLRHYIQ----DLDERIDL-LINITDYVAEKNLSNFEKIRRTLSV 332 + Y++ ++T+ II L+H I D+DE L LINI D++ EKN+S EK+ L+ Sbjct: 629 VKYIEENVTHINEIILLKHSINQRIADIDELNSLNLININDFINEKNISQ-EKVSYNLNK 687 Query: 333 NFYG 344 + G Sbjct: 688 LYKG 691 >UniRef50_Q4U978 Cluster: Short-chain dehydrogenase/reductase (SDR family member), putative; n=4; Theileria|Rep: Short-chain dehydrogenase/reductase (SDR family member), putative - Theileria annulata Length = 424 Score = 40.3 bits (90), Expect = 0.040 Identities = 36/162 (22%), Positives = 73/162 (45%), Gaps = 5/162 (3%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERP----DIEISYLQM 185 VA+V G S +G + + +L + + K+ D T N ++ ++ + + +++M Sbjct: 140 VAIVTGGYSGIGLETVFQLLKWNC-KVVIFGRDKTRATNAIERMKSTKSFDENNLYFIEM 198 Query: 186 DITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 365 D+ S+ ++ +R+D LIN V+ L N + S NF G+ L Sbjct: 199 DLDNLTSVKNAASSFLNMFDRLDFLINNAG-VSTGPLKNKNGLESKFSTNFLGHFYLTNL 257 Query: 366 VYPLLNE-NARVVNVSGPAGLLATIENEDIRKRISDPTLTED 488 + LL + RV+++S + +N+ + + S +L D Sbjct: 258 LLDLLKKTEGRVISLSSIEHYMYDPKNDKLFETKSTTSLQLD 299 >UniRef50_A6QU72 Cluster: Predicted protein; n=2; Onygenales|Rep: Predicted protein - Ajellomyces capsulatus NAm1 Length = 264 Score = 40.3 bits (90), Expect = 0.040 Identities = 34/151 (22%), Positives = 67/151 (44%), Gaps = 6/151 (3%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 V L+ G++ +G + + L T GK+Y D G LK + PD + L++D Sbjct: 41 VFLLTGSSGGIGIETGRALAATG-GKVYLGVRDLEKGKEALKEILEPD-RVELLELDTGS 98 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV-YP 374 +S+ ++++L+N +A + L +N+ G+ KL+ Sbjct: 99 VESVRTAAKAFLSKSTQLNVLVNNAGIMACPEAKTADGFESQLVINYLGHFLLYKLLEQT 158 Query: 375 LLNEN-----ARVVNVSGPAGLLATIENEDI 452 LL+ + +RVVNV+ + ++ ++I Sbjct: 159 LLSSSTPEFASRVVNVASAGHHMGSVVLDNI 189 >UniRef50_A1S135 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Thermofilum pendens Hrk 5|Rep: Short-chain dehydrogenase/reductase SDR - Thermofilum pendens (strain Hrk 5) Length = 234 Score = 40.3 bits (90), Expect = 0.040 Identities = 33/131 (25%), Positives = 60/131 (45%), Gaps = 2/131 (1%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYT 200 A++ GA+S +G ++ + +G + A L S E PD +YL +D++ Sbjct: 4 AVITGASSGIGRELSAEACR--RGYRVLGIGRNEAALRELAS-EHPDC-FAYLVLDLSDP 59 Query: 201 KSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNF--EKIRRTLSVNFYGYINFGKLVYP 374 S R+ ++ + LL+N Y + + +I T++VNF + KL+ P Sbjct: 60 ASAERVAEFVSSEFRSLSLLVNNAGYGVGRGILEMTPREILDTVNVNFAAPLLLTKLLLP 119 Query: 375 LLNENARVVNV 407 + + VVNV Sbjct: 120 YMERSGTVVNV 130 >UniRef50_Q9WYS2 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Thermotoga|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Thermotoga maritima Length = 255 Score = 39.9 bits (89), Expect = 0.053 Identities = 28/139 (20%), Positives = 60/139 (43%), Gaps = 4/139 (2%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQ 182 D VALV G + LG+ + + L E + + + A K E+ +E + Sbjct: 6 DLRGRVALVTGGSRGLGFGIAQGLAEAGCSVVVASRNLEEASEAAQKLTEKYGVETMAFR 65 Query: 183 MDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNF--EKIRRTLSVNFYGYINF 356 D++ + + +L +++ ++D ++N F ++ R+ + VN +G Sbjct: 66 CDVSNYEEVKKLLEAVKEKFGKLDTVVNAAGINRRHPAEEFPLDEFRQVIEVNLFGTYYV 125 Query: 357 GKLVYPLLNE--NARVVNV 407 + + LL E N ++N+ Sbjct: 126 CREAFSLLRESDNPSIINI 144 >UniRef50_Q8EQH7 Cluster: Alcohol dehydrogenase; n=1; Oceanobacillus iheyensis|Rep: Alcohol dehydrogenase - Oceanobacillus iheyensis Length = 290 Score = 39.9 bits (89), Expect = 0.053 Identities = 39/148 (26%), Positives = 64/148 (43%), Gaps = 5/148 (3%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSL---ERPDIEISYLQMDIT 194 +V GA + +G +L + KG DT N K E IS Q D+ Sbjct: 7 IVTGANTGMGLATTIELAK--KGIHVIMACRDTKRGNEAKEKAMEESNSTNISLYQCDLG 64 Query: 195 YTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYP 374 +SI + I++ ++ID LIN V+ K+ + VN G+ L+ Sbjct: 65 SMESISKFADQIKEDFDKIDGLINNAGVVSLKHTKTEDGFESMTGVNHLGHFLLTHLLLD 124 Query: 375 LL--NENARVVNVSGPAGLLATIENEDI 452 +L +E AR++NV+ A T++ D+ Sbjct: 125 VLKKSEQARIINVASGAYKAGTLDYNDM 152 >UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Staphylococcus epidermidis|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 255 Score = 39.9 bits (89), Expect = 0.053 Identities = 27/142 (19%), Positives = 68/142 (47%), Gaps = 4/142 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VA+V+G A+ +G + + L + + + + + ++ + L++DIT+ Sbjct: 14 VAMVIGGATGIGKAMAEALAQAGANIVIADLQSNIGQETATTISTQSGVKTTSLKLDITH 73 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSN--FEKIRRTLSVNFYGYINFGKLVY 371 + + ++ Y+ +ID+L+N + + N +E+ + ++++ G + + V Sbjct: 74 SDEVNQIVDYVVREYGKIDILVNNASISIQDDTENISYEEWLKEINLSLNGAFSVAQTVG 133 Query: 372 PLLNE--NARVVNVSGPAGLLA 431 + E + ++NVS GL+A Sbjct: 134 RQMIEKGSGSIINVSSVLGLIA 155 >UniRef50_Q3WGZ8 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 1085 Score = 39.9 bits (89), Expect = 0.053 Identities = 45/164 (27%), Positives = 68/164 (41%), Gaps = 2/164 (1%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTED--DTAGFNILKSLERPDIEISYLQMDI 191 VA+V GA+S +G + L E I + A + + R D + L+ D Sbjct: 802 VAVVTGASSGIGRATARTLAEQGWQVIGVGRDPVRSAATEAEIAAAARKDGGFTMLRGDF 861 Query: 192 TYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 371 T + R+ IQ L R+D+LIN V ++ + + E T +VN + + Sbjct: 862 TLMADVRRVAGEIQHLTPRLDILINNAGGVRDRQIISAEGTEATFAVNHLAPFLLTRELT 921 Query: 372 PLLNENARVVNVSGPAGLLATIENEDIRKRISDPTLTEDELVAL 503 PLL +A S PAG I R D L D+L +L Sbjct: 922 PLLRASA----ASLPAGSTRVIAVSSSGHRAVD-GLDWDDLQSL 960 >UniRef50_Q26ER7 Cluster: Dehydrogenase/reductase; n=13; Bacteria|Rep: Dehydrogenase/reductase - Flavobacteria bacterium BBFL7 Length = 334 Score = 39.9 bits (89), Expect = 0.053 Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 5/133 (3%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNIL---KSLERPDIEISYLQMDIT 194 ++ G S G + K L K+ ++T + + KS IE+S +QMD+ Sbjct: 43 VITGTTSGTGLEAAKILL-AKDAKVVMLNRNNTKAQDTIAKFKSELGNHIEVSNIQMDLA 101 Query: 195 YTKSIIRLRHYIQDLDERIDLLI-NITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 371 S+ + + ID LI N K + + L VN YG L++ Sbjct: 102 QLASVRKAAKQVLSTIPHIDALICNAAIAQVPKQVLTVDGFESQLGVNHYGNFLLQGLLF 161 Query: 372 PLLNE-NARVVNV 407 PL+++ N R+V V Sbjct: 162 PLIDKSNGRIVTV 174 >UniRef50_Q03B39 Cluster: Carbonyl reductase; n=2; Bacilli|Rep: Carbonyl reductase - Lactobacillus casei (strain ATCC 334) Length = 244 Score = 39.9 bits (89), Expect = 0.053 Identities = 30/152 (19%), Positives = 64/152 (42%), Gaps = 6/152 (3%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 + L+ GA +G++ L + + + + G + L + + +D+T Sbjct: 7 LTLITGADKGIGFETAMALGKRGQ-HLLVGARNQARGEQAINKLHTAGVSAELVILDVTQ 65 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFE----KIRRTLSVNFYGYINFGKL 365 +I I+ +++LIN + + + +R+ VNF+G ++ + Sbjct: 66 AGTIATAAKQIEASHGYLNVLINNAGIALDAHQPPSQLPVMTMRQDFDVNFFGLVSVTQA 125 Query: 366 VYPLLNEN--ARVVNVSGPAGLLATIENEDIR 455 + PLL + A+++NVS G L + D R Sbjct: 126 MIPLLKKGAPAKIINVSSNMGSLGLASDPDSR 157 >UniRef50_A6EJT9 Cluster: Putative dehydrogenase; n=1; Pedobacter sp. BAL39|Rep: Putative dehydrogenase - Pedobacter sp. BAL39 Length = 258 Score = 39.9 bits (89), Expect = 0.053 Identities = 40/157 (25%), Positives = 72/157 (45%), Gaps = 17/157 (10%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 +ALV GA +G+Q+ K L E + +Y + + + G K+ + +Q+D+T Sbjct: 15 IALVTGANQGVGFQIAKALAE-NGYTVYVGSRNLSNG---EKAAAEIGGDTKAIQLDVTQ 70 Query: 198 TKSIIRLRHYIQDLDERIDLLIN-------------ITD--YVAEKNLSNFEKIRRTLSV 332 + +I + I+ R+DLL+N + D + ++ +++R Sbjct: 71 SSTINAVVTRIERESGRLDLLVNNAAIAHAGQPGRTLEDATEAGKATKASLDEVRTVWET 130 Query: 333 NFYGYINFGKLVYPLLNEN--ARVVNVSGPAGLLATI 437 N +G I + PLL ++ AR+VNVS G L I Sbjct: 131 NVFGVIAMTQAALPLLRKSAAARIVNVSSGLGSLTWI 167 >UniRef50_A3U1B5 Cluster: Putative short chain dehydrogenase; n=1; Oceanicola batsensis HTCC2597|Rep: Putative short chain dehydrogenase - Oceanicola batsensis HTCC2597 Length = 243 Score = 39.9 bits (89), Expect = 0.053 Identities = 35/139 (25%), Positives = 63/139 (45%), Gaps = 3/139 (2%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIE-ISYLQMDITY 197 ALV GAA +G + ++L +G + + LK + P ++ + L++D+T Sbjct: 15 ALVTGAAGGIGQAICQRLAG--QGVTLYAGD--------LKQVSIPTLDGLISLELDVTS 64 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNF--EKIRRTLSVNFYGYINFGKLVY 371 T+ I+ +D+L+N A +L N + RR +N +G K Sbjct: 65 TEDWAAAAERIRADGRVLDILVNNAGIYAPASLENETGDGFRRLTDINQFGVFWGMKSAA 124 Query: 372 PLLNENARVVNVSGPAGLL 428 PL+ E +VN+S G++ Sbjct: 125 PLMPEGGAIVNLSSIGGMV 143 >UniRef50_A0UZI2 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Clostridium cellulolyticum H10|Rep: Short-chain dehydrogenase/reductase SDR - Clostridium cellulolyticum H10 Length = 246 Score = 39.9 bits (89), Expect = 0.053 Identities = 36/155 (23%), Positives = 68/155 (43%), Gaps = 8/155 (5%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLE---RPDIEISYL 179 M VA+V G + LG ++ +L + + D++G K+LE + ++ Y+ Sbjct: 1 MAKVAIVTGGSRGLGRAMVLRLGKMGYN-VVMNYVSDSSGKECEKNLEELRKMGVDGIYI 59 Query: 180 QMDI-TYTKSIIRLRHYIQDLDERIDLLINITDYV--AEKNLSNFEKIRRTLSVNFYGYI 350 Q D TY ++ ++ ++ID+L+N AE + + VN + Sbjct: 60 QADASTYEGCETVVKAAVEKFGDKIDVLVNNAGVSNNAEFYKQDHADYEWLIRVNLLSVM 119 Query: 351 NFGKLVYPLLNE--NARVVNVSGPAGLLATIENED 449 + +LV P + E ++N+S GL+ I D Sbjct: 120 HMTRLVLPYMVEAKKGNIINISSIGGLMGVINQAD 154 >UniRef50_Q9LZA3 Cluster: Putative uncharacterized protein F8F6_280; n=1; Arabidopsis thaliana|Rep: Putative uncharacterized protein F8F6_280 - Arabidopsis thaliana (Mouse-ear cress) Length = 280 Score = 39.9 bits (89), Expect = 0.053 Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 3/107 (2%) Frame = +3 Query: 99 YFTTEDDTAGFNILKSLERPDIEISYLQMDITYTKSIIRLRHYIQDLDERIDLLINITDY 278 + TT D N L+ ++++S Q+ + + S+ + + DL + LL+N Sbjct: 42 FSTTLSDIKRQNEDAKLKAFEVDMSSFQLVLKFRSSLEQWL-FESDLHSSVQLLVNNAGI 100 Query: 279 VAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPLLNEN---ARVVNVS 410 +A + E R ++ N+ G + KL+ PLL + +RVVNV+ Sbjct: 101 LATSSRPTVEGFDRMIATNYVGAFSLTKLLLPLLRNSPVPSRVVNVT 147 >UniRef50_A7RYH1 Cluster: Predicted protein; n=7; Eumetazoa|Rep: Predicted protein - Nematostella vectensis Length = 180 Score = 39.9 bits (89), Expect = 0.053 Identities = 27/142 (19%), Positives = 66/142 (46%), Gaps = 7/142 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTET--HKGKIYFTTEDDTAGFNILKSLERPDIEISYL-QMD 188 VA++ G +S +G L + + ++Y T + ++ + + + ++ ++D Sbjct: 5 VAVITGCSSGIGLATASILAKDGEKRFRVYATMRNLDKKGSLESACQNALGDTLFIRELD 64 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINIT--DYVAEKNLSNFEKIRRTLSVNFYGYINFGK 362 ++ S+ + I + + RID+L+N ++ ++ T + NF+G + K Sbjct: 65 VSSDDSVEEALNAIYEEEGRIDILVNNAGISHIGMLETQTQSLVKETFNTNFFGVLRMSK 124 Query: 363 LVYPLL--NENARVVNVSGPAG 422 V P + + + ++N+S AG Sbjct: 125 AVIPRMKSDHSGHIINISSTAG 146 >UniRef50_A4HMC2 Cluster: Putative uncharacterized protein; n=3; Leishmania|Rep: Putative uncharacterized protein - Leishmania braziliensis Length = 1982 Score = 39.9 bits (89), Expect = 0.053 Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 6/81 (7%) Frame = +2 Query: 29 RRRRKQPRIPSLKKTHRDSQRKNLLHYRR*HSRLQHPQEP--GEARHRNQLL--ANGHH- 193 +RRR QP+ +++HR+ +RK+ RR R + P+ G RHR+Q + HH Sbjct: 774 QRRRLQPQGCRQRRSHREKRRKSARQRRRKRGRSRGPRSTGGGGGRHRSQQHRGQSRHHR 833 Query: 194 -VYKEHHQTEALHPGSRRKDR 253 Y HH ++ RR+ R Sbjct: 834 SSYHHHHNPKSTKSSRRRRRR 854 >UniRef50_A5DIM4 Cluster: Putative uncharacterized protein; n=1; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 289 Score = 39.9 bits (89), Expect = 0.053 Identities = 40/140 (28%), Positives = 71/140 (50%), Gaps = 5/140 (3%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYT 200 ALV GA+S +GY + +L E +G F + +K LE D+ I+ ++D+ Sbjct: 6 ALVTGASSGIGYALAIELAE--RGYRVFA---GARRLSRMKPLE--DLGITTFELDVGSL 58 Query: 201 KSIIRLRHYI-QDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 +SI R +I ++ ++DLL N I + + + EK ++ +N YG I + + Sbjct: 59 ESIERAVEFISENTGGKLDLLFNNAGIQCFSPAVEVDD-EKFQKCFQINVYGPIRLIREL 117 Query: 369 YPLLNENARVVNVSG-PAGL 425 PL+ ++ V+ +G AGL Sbjct: 118 APLVIKSRGVIAFTGSTAGL 137 >UniRef50_Q97A90 Cluster: DTDP-4-dehydrorhamnose reductase; n=1; Thermoplasma volcanium|Rep: DTDP-4-dehydrorhamnose reductase - Thermoplasma volcanium Length = 280 Score = 39.9 bits (89), Expect = 0.053 Identities = 40/146 (27%), Positives = 62/146 (42%), Gaps = 13/146 (8%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTED--DTAGFNILKSLERPDIEISYL------ 179 L+ G LG ++LK + G I D D + +L S PDI I+ Sbjct: 5 LIFGHTGQLGRELLKLVPNAISGSINGKRVDITDYSEIALLFSQASPDIVINSAAFTNVD 64 Query: 180 ----QMDITYTKSIIRLRHYIQDLDERIDLLINI-TDYVAEKNLSNFEKIRRTLSVNFYG 344 + + Y + I +R+ ++ D+ LI I TDYV N+++ +N+YG Sbjct: 65 RCEKEREKAYLVNAIGVRNIVKLCDKYNSKLIQISTDYVFNGERGNYKEDDIPDPINYYG 124 Query: 345 YINFGKLVYPLLNENARVVNVSGPAG 422 Y Y L ++N VV SG G Sbjct: 125 YTKSIGDAYALSSDNTIVVRTSGVFG 150 >UniRef50_UPI000023CB35 Cluster: hypothetical protein FG03285.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG03285.1 - Gibberella zeae PH-1 Length = 272 Score = 39.5 bits (88), Expect = 0.070 Identities = 29/138 (21%), Positives = 65/138 (47%), Gaps = 4/138 (2%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMD 188 M V V G++ +G +++++ G + T + + + L + P+ +I + +D Sbjct: 1 MARVWFVTGSSRGVGRALVEQILAA--GDMVVATARNPSQLDDLVTRYGPN-KILAIALD 57 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNL--SNFEKIRRTLSVNFYGYINFGK 362 + + D RID+++N Y ++ ++FE ++VNF+G +N K Sbjct: 58 VANAQQASETVREAVDKFGRIDVVVNNAGYAEMSSVEDTSFESFHSQVNVNFFGVVNVTK 117 Query: 363 LVYPLLNE--NARVVNVS 410 V P++ + + ++ VS Sbjct: 118 AVLPIMRQQKSGHIIQVS 135 >UniRef50_O53537 Cluster: Possible oxidoreductase; n=9; cellular organisms|Rep: Possible oxidoreductase - Mycobacterium tuberculosis Length = 317 Score = 39.5 bits (88), Expect = 0.070 Identities = 41/194 (21%), Positives = 81/194 (41%), Gaps = 7/194 (3%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLER--PDIEISY 176 D +A++ GA S LG+ + ++L+ + + G ++ + PD +++ Sbjct: 11 DLSGKLAIITGANSGLGFGLARRLSAAG-ADVIMAIRNRAKGEAAVEEIRTAVPDAKLTI 69 Query: 177 LQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVA-EKNLSNFEKIRRTLSVNFYGYIN 353 +D++ S+ L + IDLLIN + + ++ + N G+ Sbjct: 70 KALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGHFA 129 Query: 354 FGKLVYPLLN--ENARVVNVSGPAGLLATIENEDIRKRISDPTLTE--DELVALIQEYEH 521 + PLL + ARVV++S A I +D++ S +T +A++ Sbjct: 130 LTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFARE 189 Query: 522 AARRGVEKTEGWGM 563 RR + GWG+ Sbjct: 190 LDRR--SRAAGWGI 201 >UniRef50_Q1VHF4 Cluster: Probable oxidoreductase protein, short-chain dehydrogenase-reductase (SDR) family; n=1; Psychroflexus torquis ATCC 700755|Rep: Probable oxidoreductase protein, short-chain dehydrogenase-reductase (SDR) family - Psychroflexus torquis ATCC 700755 Length = 245 Score = 39.5 bits (88), Expect = 0.070 Identities = 34/149 (22%), Positives = 64/149 (42%), Gaps = 4/149 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VA+V G +G + L E K+ T+ D F L SL+ ++S+ + DIT Sbjct: 12 VAIVTGGTRGIGLAIAHALGEAG-AKLVVTSRTDK--FGGLDSLKEAGHDVSFFESDITD 68 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNF--EKIRRTLSVNFYGYINFGKLVY 371 ++ Y D ID+L+N + F E + + +++N + V Sbjct: 69 KSVPQKIIDYTLDKHGVIDILVNNAGVAQHGEMEEFNDELLDKIMNINVDSVFRMCRSVL 128 Query: 372 -PLLNENARVV-NVSGPAGLLATIENEDI 452 P+ + + V+ N+ +GL++ I + Sbjct: 129 TPMKKQGSGVILNIGSISGLVSNIPQPQV 157 >UniRef50_A5UTC3 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Chloroflexaceae|Rep: Short-chain dehydrogenase/reductase SDR - Roseiflexus sp. RS-1 Length = 239 Score = 39.5 bits (88), Expect = 0.070 Identities = 28/140 (20%), Positives = 62/140 (44%), Gaps = 5/140 (3%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VA+++GA+S +GY+ ++L + D +++ + + D+T Sbjct: 7 VAIIIGASSGVGYETARRLAREGVSVVAAARRRDRLE-SLVAEIAGEGGRAVAIPTDVTD 65 Query: 198 TKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 ++ + RL +L R+D+L+N +T +A + + R + N +G + V Sbjct: 66 SEQVERLVESAVNLFGRVDILVNSAGVTHKIAPLEQFSNDDFRLVIETNLHGTFYAARAV 125 Query: 369 YPLL--NENARVVNVSGPAG 422 P + + +VN++ G Sbjct: 126 IPHMKRQRSGTIVNIASRVG 145 >UniRef50_A4AT28 Cluster: Dehydrogenase; n=2; Flavobacteriales|Rep: Dehydrogenase - Flavobacteriales bacterium HTCC2170 Length = 254 Score = 39.5 bits (88), Expect = 0.070 Identities = 32/146 (21%), Positives = 66/146 (45%), Gaps = 4/146 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VA++ G + ++G + K+ E+ K+ + + + +S+++ LQ D++ Sbjct: 13 VAVITGGSRSIGLAIAKRFYESGM-KVAILSVGEGSAKKAAESIDKSGTGALGLQCDVSD 71 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNF--EKIRRTLSVNFYG-YINFGKLV 368 S+ I L RID+L+N + ++ E + LS N G + K + Sbjct: 72 ESSVELALEKINSLFGRIDILVNSAGILDMSSIEEMTTEHWDKVLSTNLRGTFTTIQKSI 131 Query: 369 -YPLLNENARVVNVSGPAGLLATIEN 443 Y ++ R++N+S +G + EN Sbjct: 132 KYLEKSKFPRIINISSNSGRMGGFEN 157 >UniRef50_A2FH32 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=1; Trichomonas vaginalis G3|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Trichomonas vaginalis G3 Length = 358 Score = 39.5 bits (88), Expect = 0.070 Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 3/133 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYF---TTEDDTAGFNILKSLERPDIEISYLQMD 188 +A++ G +G+++ ++L + I T + A ++K +IEI L++D Sbjct: 83 IAVLTGGNRGMGFEIARELAKKQYHLIIGCRNVTNGEEAKEKLIKESGNTNIEI--LELD 140 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 ++ SI R + + E+I L+N + + + TL N+ G + + Sbjct: 141 VSSIDSINRFGNILLSRREKIIRLMNNAGAMTHTFRTTSDGFENTLETNYIGPLLLTLKL 200 Query: 369 YPLLNENARVVNV 407 PL+ +R+VN+ Sbjct: 201 LPLMPPESRIVNM 213 >UniRef50_Q6CP24 Cluster: Similarities with sp|P40579 Saccharomyces cerevisiae YIR035c; n=1; Kluyveromyces lactis|Rep: Similarities with sp|P40579 Saccharomyces cerevisiae YIR035c - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 186 Score = 39.5 bits (88), Expect = 0.070 Identities = 32/141 (22%), Positives = 63/141 (44%), Gaps = 4/141 (2%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMD 188 M V LV G + +G +++KL KI LK+ + + Y+ D Sbjct: 1 MSKVFLVTGVSRGIGSSIVEKLCSIETTKIVIGIARSKDKLEELKT--QYSGKFDYICGD 58 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLI---NITDYVAEKNLSNFEKIRRTLSVNFYGYINFG 359 ++ ++I ++I+ +R+D ++ + D V + N + K ++ +NF+ ++ Sbjct: 59 VSDEETITEAVNFIESKYKRLDGIVANAGVLDPVEDVNNIHISKWKQLFDINFFSVVSLV 118 Query: 360 KLVYPLLNE-NARVVNVSGPA 419 PLL + N +V VS A Sbjct: 119 GHALPLLKQSNGNIVLVSSGA 139 >UniRef50_UPI0000D9AA6B Cluster: PREDICTED: hypothetical protein; n=1; Macaca mulatta|Rep: PREDICTED: hypothetical protein - Macaca mulatta Length = 754 Score = 39.1 bits (87), Expect = 0.093 Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 2/91 (2%) Frame = +2 Query: 8 YVQRSAGRRRRKQPRIPSLKKTHRD--SQRKNLLHYRR*HSRLQHPQEPGEARHRNQLLA 181 ++ + G RR ++PR P K HR+ S R+ Y + S ++ GE RH+ + Sbjct: 635 WLYKEEGDRRHRKPRDPDRDKKHREKSSTREKREKYSKEKSN-SFSEKEGEERHKEKRHK 693 Query: 182 NGHHVYKEHHQTEALHPGSRRKDRFADKHHR 274 H E H+T A RK+R A HR Sbjct: 694 EVLHFDDERHRTSA-----DRKERSAKDEHR 719 >UniRef50_Q88ZF7 Cluster: Short-chain dehydrogenase/oxidoreductase; n=2; Bacteria|Rep: Short-chain dehydrogenase/oxidoreductase - Lactobacillus plantarum Length = 299 Score = 39.1 bits (87), Expect = 0.093 Identities = 38/139 (27%), Positives = 62/139 (44%), Gaps = 4/139 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 V L+ GA+S +G KL +G I + A I K + + L++D+T Sbjct: 6 VILITGASSGIGKATALKLQA--QGNIVYG-----AARRIEKMTDLAAAGVHVLKVDVTD 58 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSN--FEKIRRTLSVNFYGYINFGKLVY 371 ++I IQ RID+LIN Y + +L + + VN +G + +LV Sbjct: 59 EATLIAAVKTIQVEQGRIDVLINNAGYGSYGSLEDVPVAEGEYQFKVNVFGVMRLTQLVL 118 Query: 372 PLL--NENARVVNVSGPAG 422 PL+ R+++VS G Sbjct: 119 PLMRAQHRGRIIDVSSIGG 137 >UniRef50_Q7NJ27 Cluster: Gll2005 protein; n=3; Cyanobacteria|Rep: Gll2005 protein - Gloeobacter violaceus Length = 290 Score = 39.1 bits (87), Expect = 0.093 Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 3/63 (4%) Frame = +3 Query: 249 IDLLINITDYV-AEKNLSNF--EKIRRTLSVNFYGYINFGKLVYPLLNENARVVNVSGPA 419 +++L+N Y A++N + E+ RRTL N +GY + + P LN ++N Sbjct: 125 LNILVNNAAYQKAQENFEDITEEQFRRTLETNIFGYFHMAQAALPYLNAEDAIINTGSIV 184 Query: 420 GLL 428 GL+ Sbjct: 185 GLV 187 >UniRef50_Q3F0M6 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Bacillus thuringiensis serovar israelensis ATCC 35646|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Bacillus thuringiensis serovar israelensis ATCC 35646 Length = 248 Score = 39.1 bits (87), Expect = 0.093 Identities = 34/142 (23%), Positives = 68/142 (47%), Gaps = 6/142 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKI-YFTTEDDTAGFN-ILKSLERPDIEISYLQMDI 191 VALV+G + +G + L ++G I YFT + + N I ++ + + +DI Sbjct: 7 VALVIGGSRGIGKAITMDLA--NQGLIVYFTFQSNQKSANEIANTIGEKGGQAFPMHVDI 64 Query: 192 TYTKSIIRLRHYIQDLDERIDLLINITDYVAE--KNLSNFEKIRRTLSVNFYGYINFGKL 365 T SI +L +I+ ++RID+L+N + + + + EK + +N G + Sbjct: 65 TNEDSIHKLFQHIRSKEKRIDILVNNAGVINDGFAAMMSEEKWDHVVDLNLKGTFLCCRQ 124 Query: 366 VYPLLNENAR--VVNVSGPAGL 425 ++ R +VN++ +G+ Sbjct: 125 ALRIMMRQKRGSIVNITSTSGI 146 >UniRef50_Q2UF38 Cluster: Dehydrogenases with different specificities; n=1; Aspergillus oryzae|Rep: Dehydrogenases with different specificities - Aspergillus oryzae Length = 307 Score = 39.1 bits (87), Expect = 0.093 Identities = 29/151 (19%), Positives = 64/151 (42%), Gaps = 5/151 (3%) Frame = +3 Query: 12 CNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLER--PDIEISYLQM 185 C+ L + LG L + + ++ +++ P+ + +++ + Sbjct: 15 CSFVLTGASEGGLGGATALALASARPSHLVLLARTENKVRTVISTIKEISPETQPAFVHI 74 Query: 186 DITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 365 ++ S+ R + L +ID+LIN +A + + +TL++N G+ KL Sbjct: 75 ELEDLDSVRRAAADVLSLTSKIDVLINNAGVMAIPWSKSKSGLEKTLAINHIGHFLLTKL 134 Query: 366 VYPLL---NENARVVNVSGPAGLLATIENED 449 + P + +R+VNV+ A +A +D Sbjct: 135 LMPSILAAGPGSRIVNVTSAAYRMAPFFFDD 165 >UniRef50_A6STP3 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 309 Score = 39.1 bits (87), Expect = 0.093 Identities = 33/148 (22%), Positives = 60/148 (40%), Gaps = 9/148 (6%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLER--PDIEISY 176 D V +V G S LG + + +L + + +Y + ++ P+ I + Sbjct: 15 DLSGKVIIVTGGNSGLGKETVLQLAKHNPHLLYMGARSKAKAEEAIAEIKTTVPNANIKF 74 Query: 177 LQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINF 356 L++DI+ S+ R ++R+D+L+N + + N G F Sbjct: 75 LEIDISSLSSVKRGADAFLAENDRLDILVNNAGVMGLPPGLTEDGYESQFGTNHMGPALF 134 Query: 357 GKLVYPLL-------NENARVVNVSGPA 419 KL+ P L N + R+VN+S A Sbjct: 135 TKLLLPTLQKTSLSPNADVRIVNISSEA 162 >UniRef50_P36417 Cluster: G-box-binding factor; n=3; Dictyostelium discoideum|Rep: G-box-binding factor - Dictyostelium discoideum (Slime mold) Length = 708 Score = 39.1 bits (87), Expect = 0.093 Identities = 17/83 (20%), Positives = 39/83 (46%), Gaps = 3/83 (3%) Frame = +2 Query: 35 RRKQPRIPSLKKTHRDSQRKNLLHYRR*HSRLQHPQEPGEARHRNQLLANGHHVYKEHHQ 214 ++ QP + ++ H Q++ H+++ + H Q + +H Q+ HH +HHQ Sbjct: 126 QQNQPPQQNQQQQHHQQQQQQPQHHQQMQQQQHHQQMQQQQQHHQQMQQQQHHQQMQHHQ 185 Query: 215 TEA---LHPGSRRKDRFADKHHR 274 + H +++ + +HH+ Sbjct: 186 LQQHQHQHQQQQQQQQHQQQHHQ 208 >UniRef50_UPI00005873A1 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 335 Score = 38.7 bits (86), Expect = 0.12 Identities = 29/145 (20%), Positives = 62/145 (42%), Gaps = 4/145 (2%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERP--DIEISYLQMDITY 197 +V GA + +G + + L ++ D G K + + ++ ++++++ Sbjct: 62 IVTGANTGIGKETARDLAR-RGARVILACRDAVRGREAEKDIRMSTGNDDVIFMKLNLAS 120 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPL 377 SI + +ER+D+L+N + + +L E VN G+ ++ Sbjct: 121 FDSIRHFAQEFNNTEERLDILVNNAGVINDGSLRTEEGHELVFGVNHLGHFLLTNILLDK 180 Query: 378 LNENA--RVVNVSGPAGLLATIENE 446 L + A RV+NVS A + ++ E Sbjct: 181 LQKCAPSRVINVSSDAYMFGKLDLE 205 >UniRef50_UPI000045C012 Cluster: COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); n=1; Nostoc punctiforme PCC 73102|Rep: COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - Nostoc punctiforme PCC 73102 Length = 278 Score = 38.7 bits (86), Expect = 0.12 Identities = 34/147 (23%), Positives = 67/147 (45%), Gaps = 7/147 (4%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMD 188 M V + GA S +G K ++ ++ T + N L+ + ++ +++Q+D Sbjct: 1 MSKVWFITGAGSGIGTGTAKAALQSGD-RVVATGRNLDKVRNALRDVASENL--AFVQLD 57 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEK-----IRRTLSVNFYGYIN 353 ++ + RID+L+N Y L NFE+ I R + NFYG + Sbjct: 58 VSDEVQAKTAIEEAVNRFGRIDVLVNNAGYSL---LGNFEEMTTTDIERQFATNFYGVVY 114 Query: 354 FGKLVYPLLNE--NARVVNVSGPAGLL 428 + V P++ + + ++N+S AG++ Sbjct: 115 VMRAVLPIMRQQRSGHIINISSVAGVV 141 >UniRef50_Q97DJ3 Cluster: Short-chain alcohol dehydrogenase family protein; n=2; Bacteria|Rep: Short-chain alcohol dehydrogenase family protein - Clostridium acetobutylicum Length = 291 Score = 38.7 bits (86), Expect = 0.12 Identities = 33/135 (24%), Positives = 62/135 (45%), Gaps = 4/135 (2%) Frame = +3 Query: 27 VVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLE--RPDIEISYLQMDITYT 200 + GA S LG V +L + + T + K LE P +I + D++ Sbjct: 9 ITGATSGLGKLVAIELVK-RDAHLILTARNKERAEATKKMLESINPKAKIDFFFGDLSVM 67 Query: 201 KSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYG-YINFGKLVYPL 377 + + R+ I+ + RID+L+N A + + + ++VN+ ++ L+ L Sbjct: 68 RDVKRVGEEIKAVHPRIDVLVNNAGLHAFEQRVTSDGLAEMMAVNYLAPWLLTNTLLQSL 127 Query: 378 L-NENARVVNVSGPA 419 + + NAR+VNV+ A Sbjct: 128 IASRNARIVNVASEA 142 >UniRef50_A4WW43 Cluster: Putative uncharacterized protein; n=1; Rhodobacter sphaeroides ATCC 17025|Rep: Putative uncharacterized protein - Rhodobacter sphaeroides ATCC 17025 Length = 226 Score = 38.7 bits (86), Expect = 0.12 Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 4/87 (4%) Frame = +2 Query: 26 GRRRRKQPRIPSLKKTHRDSQRKNLLHYRR*HSRLQHP--QEPGEARHRNQLLANGHHVY 199 G + QP S K H+ + + H + R +HP EPG R +++ LA GH + Sbjct: 125 GEALQHQPVGQSRKPRHQ-KRTSHQRHGKGQARRSRHPLAHEPGGDRAQHEELAMGHVHH 183 Query: 200 KEHHQTEALHPGSRRKDRFADK--HHR 274 H + EA G +R+ R AD+ HHR Sbjct: 184 PHHAEDEAQPRGRQREHRRADQPLHHR 210 >UniRef50_A3PT80 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Actinomycetales|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 262 Score = 38.7 bits (86), Expect = 0.12 Identities = 35/144 (24%), Positives = 62/144 (43%), Gaps = 7/144 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 V +V GA + +G QV L +G + + D G L +S +D+T Sbjct: 7 VFVVTGAGNGMGRQVTLDLLR--RGALVAAADVDEVGLTGTARLAMAGTRLSTHVLDVTD 64 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNF-----EKIRRTLSVNFYGYINFGK 362 ++ + + D+ R+D L+NI + + F E R ++VNF G ++ + Sbjct: 65 RDAVAAMPGRVVDVHGRVDGLVNIAGVI--HRFAPFIDLPPETADRIMAVNFTGTVDMCR 122 Query: 363 LVYPLL--NENARVVNVSGPAGLL 428 P+L A + N+S + LL Sbjct: 123 AFLPVLLARPEANLTNMSSLSALL 146 >UniRef50_A3ET57 Cluster: Short-chain alcohol dehydrogenase; n=2; Bacteria|Rep: Short-chain alcohol dehydrogenase - Leptospirillum sp. Group II UBA Length = 286 Score = 38.7 bits (86), Expect = 0.12 Identities = 32/138 (23%), Positives = 64/138 (46%), Gaps = 6/138 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSL-ERPDIEISYLQMDIT 194 VAL+ GA LG ++++ + + ++ + I SL +R D +S+ D++ Sbjct: 5 VALITGANGGLGEFLVRRFWDAGYS-LCLVARNERSIMAISSSLPKRNDQNVSFFACDLS 63 Query: 195 YTKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 365 ++ L I+ +R+D+L+N + S+ + +RT+ VN + + Sbjct: 64 DPVLVVELTKTIRKHHQRLDVLVNNAATHGPIGPLWESDLQAWQRTIQVNLLSPVALCRA 123 Query: 366 VYPLLNEN--ARVVNVSG 413 P + EN ++NVSG Sbjct: 124 FVPWMKENGGGSIINVSG 141 >UniRef50_Q7K0F7 Cluster: GH19857p; n=4; Diptera|Rep: GH19857p - Drosophila melanogaster (Fruit fly) Length = 355 Score = 38.7 bits (86), Expect = 0.12 Identities = 32/153 (20%), Positives = 64/153 (41%), Gaps = 8/153 (5%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNI--LKSLERPDIEISYLQMDI 191 +A++ G +G ++++KL + + A + + L ++ Q+D+ Sbjct: 69 IAVITGGNRGIGLRIVEKLLACDMTVVMGVRDPKIAETAVASIVDLNATKGKLICEQLDV 128 Query: 192 TYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 371 KS+ I++ ++DLL+N + + ++NF G+ L+ Sbjct: 129 GDLKSVKAFAQLIKERYSKVDLLLNNAGIMFAPFKLTADGYESHFAINFLGHFLLTHLLL 188 Query: 372 PLLN------ENARVVNVSGPAGLLATIENEDI 452 P L N+R+VNVS L+ I +DI Sbjct: 189 PQLRAAGKEGRNSRIVNVSSCVNLIGRINYKDI 221 >UniRef50_A2E0P5 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=1; Trichomonas vaginalis G3|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Trichomonas vaginalis G3 Length = 319 Score = 38.7 bits (86), Expect = 0.12 Identities = 30/128 (23%), Positives = 54/128 (42%), Gaps = 3/128 (2%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKI-YFTTEDDTAGFNILKSLERPDIEISYLQMDITYT 200 ++ G +S LG + K+ + + + K + D I + D+T Sbjct: 37 VITGGSSGLGIALAKEAFNNGAAHVTLIARKQEQLEAASAKIPHKEDQAIHIISADVTNV 96 Query: 201 KSIIRLRHYIQDLDERIDLLINITDYV--AEKNLSNFEKIRRTLSVNFYGYINFGKLVYP 374 +S+ + I+DL +ID L Y E + E+ + ++VN G I ++ Y Sbjct: 97 ESLQNAFNQIKDLGLKIDYLFPNAGYARPGEFDQLPIEEFKNLMNVNGIGAILSTRMAYT 156 Query: 375 LLNENARV 398 LLNE A + Sbjct: 157 LLNEGAHI 164 >UniRef50_Q4J702 Cluster: Oxidoreductase; n=2; Sulfolobus|Rep: Oxidoreductase - Sulfolobus acidocaldarius Length = 264 Score = 38.7 bits (86), Expect = 0.12 Identities = 25/110 (22%), Positives = 53/110 (48%), Gaps = 2/110 (1%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYT 200 A+V+GA+S +G + + +E GK+ + D+ + SL E+++++ DIT Sbjct: 14 AVVLGASSGIGKAIAEMFSEMG-GKVVLSDIDEEGLKRLSDSLRSRGHEVNHMKCDITDL 72 Query: 201 KSIIRLRHYIQDLDERIDLLINITDYVAEKNLSN--FEKIRRTLSVNFYG 344 + +L ++ + +D L K++ N +E + ++VN G Sbjct: 73 NQVKKLVNFSLSVYGNVDALYVTPSINVRKSIENYTYEDFEKVINVNLKG 122 >UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=1; Bacillus halodurans|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Bacillus halodurans Length = 247 Score = 38.3 bits (85), Expect = 0.16 Identities = 33/141 (23%), Positives = 59/141 (41%), Gaps = 4/141 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VA+V GA +G +++K E + A I K+L + + +SY+ + Sbjct: 7 VAIVTGATRGIGKEIVKTFVEQGAFVYGIYASNHEAAREIEKTLNQGEKCVSYVSGSVDD 66 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNF--EKIRRTLSVNFYGYIN--FGKL 365 I L + D R+D+L+N ++ L + ++ L VNF G L Sbjct: 67 QLFIHSLFKSVVDKHNRLDILVNNAGITRDQFLFQMDDQSWQQVLQVNFGGTYTCCHAAL 126 Query: 366 VYPLLNENARVVNVSGPAGLL 428 Y + ++VNV G++ Sbjct: 127 PYMERKKQGKIVNVVSVTGVV 147 >UniRef50_Q73PW1 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=1; Treponema denticola|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Treponema denticola Length = 265 Score = 38.3 bits (85), Expect = 0.16 Identities = 34/145 (23%), Positives = 65/145 (44%), Gaps = 4/145 (2%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMD 188 M +A+V G +S +G ++ K L K YF F L P + ++ +D Sbjct: 1 MEKIAIVAGGSSGIGLEITKALVL----KDYFVYTMSRREF-----LSLPQEKSKHISLD 51 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDY--VAEKNLSNFEKIRRTLSVNFYGYINFGK 362 IT +++ + I + + RIDL + + + +N E+ ++ + VNF+G F K Sbjct: 52 ITDEENLTKAFSDIWEKEGRIDLAVCASGFGISGAVEFTNLEEAKKQMDVNFFGAFLFIK 111 Query: 363 LVYPLLNENA--RVVNVSGPAGLLA 431 + + ++ +S AG +A Sbjct: 112 TAASYMRPQSFGKIFVISSIAGEIA 136 >UniRef50_A3Y6H5 Cluster: Short chain dehydrogenase; n=4; Bacteria|Rep: Short chain dehydrogenase - Marinomonas sp. MED121 Length = 245 Score = 38.3 bits (85), Expect = 0.16 Identities = 28/127 (22%), Positives = 63/127 (49%), Gaps = 3/127 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VALV GA +G + + L + K+Y D ++ +N+ +E+ ++ L++D+ Sbjct: 9 VALVTGANRGIGKAITESLLKHGAKKVYLAVRDLSSTYNL---VEKYGDKVVTLKLDMAN 65 Query: 198 TKSIIRLRHYIQDLDERIDL--LINITDYVAEKNLSNFEK-IRRTLSVNFYGYINFGKLV 368 + I L +D++ I+ ++ I D E+ F++ + + L +N +G + + + Sbjct: 66 PEEIKALAAAAKDVEVVINNAGILEIADLFEEE----FDQALEQQLDINLFGLVRIARAL 121 Query: 369 YPLLNEN 389 P++ N Sbjct: 122 TPVIEAN 128 >UniRef50_Q2QLP7 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein, expressed; n=1; Oryza sativa (japonica cultivar-group)|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein, expressed - Oryza sativa subsp. japonica (Rice) Length = 302 Score = 38.3 bits (85), Expect = 0.16 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 4/95 (4%) Frame = +3 Query: 162 IEISYLQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNF--EKIRRTLSVN 335 ++ +L +D+T +S+ + R+D+L+N L+ E +RR + VN Sbjct: 60 LDADHLPLDVTSDESVEGAVARVLAEHGRVDVLVNNAGIGCTGPLAELRGEAVRRAMDVN 119 Query: 336 FYGYINFGKLVYPLL--NENARVVNVSGPAGLLAT 434 F G + + V P + + RVVNV G AT Sbjct: 120 FLGQLRMVRAVAPHMASRRSGRVVNVGSVVGTAAT 154 >UniRef50_A2R9D0 Cluster: Remark: during fruiting body development; n=6; Trichocomaceae|Rep: Remark: during fruiting body development - Aspergillus niger Length = 255 Score = 38.3 bits (85), Expect = 0.16 Identities = 35/135 (25%), Positives = 68/135 (50%), Gaps = 7/135 (5%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLT-ETHKGKIYFTTEDDTAGFNILKSL--ERPDIEISYLQMDIT 194 LV GA+ +G +++++L +T + + T+G + + L + PD + ++ +D+T Sbjct: 5 LVTGASRGIGLELVRQLAAKTSETVQTISAAARTSGGPLFQELLQQHPD-RVIFVPLDVT 63 Query: 195 YTKSIIR-LRHYIQDLDER-IDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 +S+ + H L+ + +D+LIN + + N + + TL VN G + Sbjct: 64 EKESVKNAVTHVATALNGKGLDVLINNAGVMTPGTVENMDDLEDTLRVNVGGVHLVTREF 123 Query: 369 YPLL-NEN-ARVVNV 407 PLL N N R+VN+ Sbjct: 124 LPLLRNGNKKRIVNI 138 >UniRef50_A1DNP7 Cluster: Short chain dehydrogenase/reductase family oxidoreductase, putative; n=1; Neosartorya fischeri NRRL 181|Rep: Short chain dehydrogenase/reductase family oxidoreductase, putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181)) Length = 225 Score = 38.3 bits (85), Expect = 0.16 Identities = 30/140 (21%), Positives = 60/140 (42%), Gaps = 4/140 (2%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 203 LV G + +G ++ +L ++ + F + + L R + Y+ +D+ Sbjct: 5 LVTGCSRGIGLELTCQLANSNDDIVIFASARSFNNPKFQELLRRHPERVVYVPLDVADQG 64 Query: 204 SIIRLRHYI-QDLDER-IDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPL 377 SI I +LD + +D+LIN ++ + + N G NF + V PL Sbjct: 65 SIKNAVDIITSNLDGKGLDVLINNAGVMSNGPAEEMDDLEEVFRTNVIGVHNFTRAVLPL 124 Query: 378 L--NENARVVNVSGPAGLLA 431 + + +V+N+S G ++ Sbjct: 125 MRKGKEKKVLNISTTLGSIS 144 >UniRef50_Q8WVS4 Cluster: WD repeat-containing protein 60; n=24; Amniota|Rep: WD repeat-containing protein 60 - Homo sapiens (Human) Length = 1066 Score = 38.3 bits (85), Expect = 0.16 Identities = 20/81 (24%), Positives = 32/81 (39%) Frame = +2 Query: 8 YVQRSAGRRRRKQPRIPSLKKTHRDSQRKNLLHYRR*HSRLQHPQEPGEARHRNQLLANG 187 ++ + G RR ++PR P K HR+ + + + GE RH+ + G Sbjct: 205 WLYKEEGERRHRKPREPDRDKKHREKSSTREKREKYSKEKSNSFSDKGEERHKEKRHKEG 264 Query: 188 HHVYKEHHQTEALHPGSRRKD 250 H E HQ+ KD Sbjct: 265 FHFDDERHQSNVDRKEKSAKD 285 >UniRef50_Q4D3W0 Cluster: Putative uncharacterized protein; n=4; Trypanosoma cruzi|Rep: Putative uncharacterized protein - Trypanosoma cruzi Length = 929 Score = 28.7 bits (61), Expect(2) = 0.21 Identities = 15/46 (32%), Positives = 19/46 (41%) Frame = +2 Query: 137 PQEPGEARHRNQLLANGHHVYKEHHQTEALHPGSRRKDRFADKHHR 274 P P E H Q +N +E H+ +LH R R HHR Sbjct: 396 PLPPSEEAHHRQHFSN-----EERHEERSLHKRGREHSRGRHHHHR 436 Score = 28.3 bits (60), Expect(2) = 0.21 Identities = 20/61 (32%), Positives = 30/61 (49%) Frame = +2 Query: 371 PATERER*SRKRVWTSWSSSHNRKRRYKKENQRSHIDRR*TGRFDPRIRTRRKKGSREDR 550 PA + SR+R S S ++R+RR+++ RSH RR R R + R + G Sbjct: 441 PAAKERAWSRRRRHRSSSRHYSRERRHRR--GRSHDRRRDKKRRGSRRQHRHRSGDVSSS 498 Query: 551 R 553 R Sbjct: 499 R 499 >UniRef50_Q9RT30 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=2; Deinococcus|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Deinococcus radiodurans Length = 283 Score = 37.9 bits (84), Expect = 0.21 Identities = 35/142 (24%), Positives = 58/142 (40%), Gaps = 3/142 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 V ++ GA+S +G ++L + DT ++ + L+ + + D+T Sbjct: 33 VVVLTGASSGIGLATAEELAAQGYALVLAARRADTLR-DLARRLDPSGSRVIAVPTDVTD 91 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKN-LSNFEKIRRTLSVNFYGYINFGKLVYP 374 S L + D R+D+LIN EK + R + VN I +LV P Sbjct: 92 DASRRSLLQFAHDHFGRVDVLINNAGVTVEKGWWWDDPDPLRVVRVNLEAPIELTRLVLP 151 Query: 375 LLNE--NARVVNVSGPAGLLAT 434 + N +VN+ AG AT Sbjct: 152 DMQARGNGHIVNIGSVAGRAAT 173 >UniRef50_Q2JY74 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Synechococcus|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria bacteriumYellowstone A-Prime) Length = 291 Score = 37.9 bits (84), Expect = 0.21 Identities = 30/142 (21%), Positives = 61/142 (42%), Gaps = 4/142 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 V L+ GA++ +G V + + ++ + N+ +E+ E + D+ Sbjct: 8 VVLITGASAGIGKAVALEAAK-RGARLVLAARREELLQNVKDLVEKQGTEALVVPTDMAD 66 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDY--VAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 371 T + L D R+D+L+N Y + + +RR VN +G + + Sbjct: 67 TAQVEALAQKALDRFGRVDILVNNAGYGQMGPVEEVDVAAMRRQFEVNVFGLHALTRALL 126 Query: 372 PLLNE--NARVVNVSGPAGLLA 431 P + E + R++N+S AG ++ Sbjct: 127 PQMRERGSGRILNLSSVAGQMS 148 >UniRef50_Q1DE83 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Myxococcus xanthus DK 1622|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Myxococcus xanthus (strain DK 1622) Length = 275 Score = 37.9 bits (84), Expect = 0.21 Identities = 34/140 (24%), Positives = 61/140 (43%), Gaps = 4/140 (2%) Frame = +3 Query: 15 NVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDIT 194 +V L+ GA+S +G + L+ +G I + T + +E L++D+T Sbjct: 7 SVVLITGASSGIGKACAELLSA--RGHIVYGTSR--------RPVEAAPPGYRMLELDVT 56 Query: 195 YTKSIIRLRHYIQDLDERIDLLINITDY--VAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 S+ R + + RID+++N + ++ E+ R L NF G + K V Sbjct: 57 QDDSVQRAVATVLSREGRIDVVVNNAGHALAGAAEDTSIEEARAQLDANFLGALRVCKAV 116 Query: 369 YPLLNEN--ARVVNVSGPAG 422 P + E R++ VS G Sbjct: 117 LPSMRERRAGRIIQVSSLGG 136 >UniRef50_A5GU52 Cluster: Putative uncharacterized protein SynRCC307_1508; n=1; Synechococcus sp. RCC307|Rep: Putative uncharacterized protein SynRCC307_1508 - Synechococcus sp. (strain RCC307) Length = 304 Score = 37.9 bits (84), Expect = 0.21 Identities = 36/155 (23%), Positives = 64/155 (41%), Gaps = 5/155 (3%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKG-KIYFTTEDDTAGFNILKSL--ERPDIEIS 173 D +ALV GA + +GY+ +L KG ++ D+ ++ + E P + Sbjct: 11 DQAGRLALVTGANTGIGYEAALQL--ARKGAQVLLGCRDEQRAKQAIERIQAEAPRGSVE 68 Query: 174 YLQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYIN 353 +L +D+ S+ ++ +++DLLI + + +N G+ Sbjct: 69 WLPLDLADLASVAAAAAQLRAAHQQLDLLICNAGVMVPPAGRTVDGFELQFGINHLGHFA 128 Query: 354 FGKLVYPLLN--ENARVVNVSGPAGLLATIENEDI 452 V PLL ARVV VS A L + +D+ Sbjct: 129 LVLQVLPLLQAATAARVVAVSSGAALFGRMVFDDL 163 >UniRef50_Q6NLR7 Cluster: At5g04070; n=4; Magnoliophyta|Rep: At5g04070 - Arabidopsis thaliana (Mouse-ear cress) Length = 359 Score = 37.9 bits (84), Expect = 0.21 Identities = 23/87 (26%), Positives = 45/87 (51%), Gaps = 3/87 (3%) Frame = +3 Query: 159 DIEISYLQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNF 338 ++++S Q+ + + S+ + + DL + LL+N +A + E R ++ N+ Sbjct: 115 EVDMSSFQLVLKFRSSLEQWL-FESDLHSSVQLLVNNAGILATSSRPTVEGFDRMIATNY 173 Query: 339 YGYINFGKLVYPLLNEN---ARVVNVS 410 G + KL+ PLL + +RVVNV+ Sbjct: 174 VGAFSLTKLLLPLLRNSPVPSRVVNVT 200 >UniRef50_Q0UF48 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 309 Score = 37.9 bits (84), Expect = 0.21 Identities = 31/134 (23%), Positives = 56/134 (41%), Gaps = 4/134 (2%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDD----TAGFNILKSLERPDIEI 170 D V + G + LG + L E + G+I + + A I+KS+ P ++ Sbjct: 11 DLSGKVIFITGGNAGLGKEAALILAEHNPGRILIGSRSEENARAAIAEIVKSV--PGAQL 68 Query: 171 SYLQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYI 350 + +QMD+ S+ + R+D+L+N +A + + N G+ Sbjct: 69 TPIQMDLASLSSVKEAASKVLATTSRLDVLMNNAGIMAVPPATTVDGYEIQFGTNHMGHA 128 Query: 351 NFGKLVYPLLNENA 392 KL+ PLL + A Sbjct: 129 LLTKLLLPLLLKTA 142 >UniRef50_A2R0W5 Cluster: Remark: also show homology to different oxidoreductases; n=2; Pezizomycotina|Rep: Remark: also show homology to different oxidoreductases - Aspergillus niger Length = 320 Score = 37.9 bits (84), Expect = 0.21 Identities = 36/148 (24%), Positives = 68/148 (45%), Gaps = 6/148 (4%) Frame = +3 Query: 24 LVVGAAS-NLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPD--IEISYLQMDIT 194 ++ GA ++G Q+ L + I + + +L + D I+ + +++D+T Sbjct: 27 VITGAGKPSIGSQMATSLAKAGPSHILIASRTLSKVHPVLDEIHTIDSTIKTTAVEVDLT 86 Query: 195 YTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLS-NFEKIRRTLSVNFYGYINFGKLVY 371 +S+ R I +ID+LIN +A K + + + I LS N G+ ++ Sbjct: 87 DHESVRRAAGEILAAAPKIDVLINSAGVMAIKEYTLDKQGIELQLSANHVGHFLLTNMLI 146 Query: 372 PLLNE--NARVVNVSGPAGLLATIENED 449 P L +ARVVN++ L++ ED Sbjct: 147 PALISAGSARVVNLTSAGYLVSPFRFED 174 >UniRef50_UPI0000D573E5 Cluster: PREDICTED: hypothetical protein; n=1; Tribolium castaneum|Rep: PREDICTED: hypothetical protein - Tribolium castaneum Length = 262 Score = 37.5 bits (83), Expect = 0.28 Identities = 40/176 (22%), Positives = 71/176 (40%), Gaps = 1/176 (0%) Frame = +2 Query: 29 RRRRKQPRIPSLKKTHRDSQRKNLLHYRR*HSRLQHPQEPGEARHRNQLLANGHHVYKEH 208 ++RR + R K+ + +RK RR R + ++ E R + + +E Sbjct: 7 KKRRAEQRREEKKRRDKKEKRKEKREERR-EEREERREKREERREKREERREKREERREK 65 Query: 209 HQTEALHPGSRRKDRFADKHHRLCGREEFI*FRKNPKNFER*LLRIHKLWEACVPATER- 385 + RR+ R + R GRE+ + K ER R + E ER Sbjct: 66 REERREKREERREKREEGREKREGGREKRE--ERKEKREERREKREERREERRERREERR 123 Query: 386 ER*SRKRVWTSWSSSHNRKRRYKKENQRSHIDRR*TGRFDPRIRTRRKKGSREDRR 553 E+ +R +RR K+E +R+ + R R + R + + ++ RE+RR Sbjct: 124 EKREERREKREEKRKKREERREKREERRAKSEERREKREERREKRKERREKREERR 179 >UniRef50_UPI0000ECB04E Cluster: Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-HSD 2) (Microsomal 17-beta-hydroxysteroid dehydrogenase) (20 alpha- hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH).; n=2; Gallus gallus|Rep: Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-HSD 2) (Microsomal 17-beta-hydroxysteroid dehydrogenase) (20 alpha- hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH). - Gallus gallus Length = 384 Score = 37.5 bits (83), Expect = 0.28 Identities = 34/139 (24%), Positives = 62/139 (44%), Gaps = 6/139 (4%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 203 L+ G+ + +G+ + K L G I F + G + +S LQ+DIT Sbjct: 84 LITGSDTGIGHALAKYLDNL--GFIVFAGVLNKDGPGAEELRRTCSQRLSLLQLDITNPT 141 Query: 204 SIIRLRHYIQDLDERIDL--LIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 + + + ++ L ++N I + A+ L R+ + VNF+G ++ K Sbjct: 142 QVKEAYLQVSEKVQKTGLWGVVNNAGILGFPADGELLPMSMYRQCMEVNFFGAVHVSKTF 201 Query: 369 YPLLNEN-ARVVNVSGPAG 422 PLL ++ R+VN+S G Sbjct: 202 LPLLRKSRGRLVNMSSMTG 220 >UniRef50_Q815Q8 Cluster: Short chain dehydrogenase; n=1; Bacillus cereus ATCC 14579|Rep: Short chain dehydrogenase - Bacillus cereus (strain ATCC 14579 / DSM 31) Length = 260 Score = 37.5 bits (83), Expect = 0.28 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 5/138 (3%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIY-FTTEDDTAGFNILKSLERPDIEISYLQM 185 M V ++ GA+ +GY+ L KG I ++ + T ++ K + E + Sbjct: 25 MKKVVVITGASDGIGYETAIYLAS--KGMIVVLSSRNKTKLESVRKKIHTMGGEAIVIPA 82 Query: 186 DITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFE--KIRRTLSVNFYGYINFG 359 DI+ K + +L + +L RID+LIN + L NF+ + + VN G + Sbjct: 83 DISKAKEVEQLINKTIELYGRIDVLINNAGVMPLSWLKNFDIREASSAIDVNIKGVLYGI 142 Query: 360 KLVYP--LLNENARVVNV 407 + V P L + +VN+ Sbjct: 143 RYVLPHMLTRDEGIIVNI 160 >UniRef50_Q140J4 Cluster: Putative 3-oxoacyl-(Acyl-carrier protein)reductase; n=1; Burkholderia xenovorans LB400|Rep: Putative 3-oxoacyl-(Acyl-carrier protein)reductase - Burkholderia xenovorans (strain LB400) Length = 248 Score = 37.5 bits (83), Expect = 0.28 Identities = 38/142 (26%), Positives = 64/142 (45%), Gaps = 7/142 (4%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKGKIY--FTTEDDTAGFNILKSLERPDIEISYLQMDIT 194 ALV G A +GY++ ++L E++ F E A L S + DI+I +DIT Sbjct: 11 ALVTGGAQGIGYEIAQRLLESNAEVTLWDFDREACEAAQRTLSSKGKVDIDI----VDIT 66 Query: 195 YTKSIIRLRHYIQDLDERIDLLI-NITDYVAEKNLSNF--EKIRRTLSVNFYG--YINFG 359 + + R + ID+L+ N E +S + + RR + +N Y+N Sbjct: 67 DAEEVSRAAGRMATARGHIDVLVHNAGGSGPEGTVSTYAADDWRRVIELNLNATFYVNQA 126 Query: 360 KLVYPLLNENARVVNVSGPAGL 425 + + + R+VN+S A L Sbjct: 127 VVRHMSQHGYGRIVNISSIAAL 148 >UniRef50_A5V6W3 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Sphingomonas wittichii RW1|Rep: Short-chain dehydrogenase/reductase SDR precursor - Sphingomonas wittichii RW1 Length = 251 Score = 37.5 bits (83), Expect = 0.28 Identities = 36/144 (25%), Positives = 65/144 (45%), Gaps = 5/144 (3%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VA+V GAA +G +L E +G + A + E+S+LQ+D+ Sbjct: 11 VAVVTGAAGGIGAATAAQLAE--RGARVLAVDRKPAPEEMGTGGAG---ELSFLQVDLMD 65 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAE-KNLSNF--EKIRRTLSVNFYGYINFGKLV 368 + R+ +++D +D+L+N + E ++ F + +RRT VN Sbjct: 66 EDAPDRIVDHVRDRFGALDILVNNAALIGEGASIERFSLDDLRRTFEVNVIVPFRLCAAA 125 Query: 369 YPLLNEN--ARVVNVSGPAGLLAT 434 PLL ++ R+VNV ++A+ Sbjct: 126 TPLLKQSGQGRIVNVGSVNSIMAS 149 >UniRef50_Q7XIR1 Cluster: Carbonyl reductase-like protein; n=5; Magnoliophyta|Rep: Carbonyl reductase-like protein - Oryza sativa subsp. japonica (Rice) Length = 373 Score = 37.5 bits (83), Expect = 0.28 Identities = 28/130 (21%), Positives = 61/130 (46%), Gaps = 6/130 (4%) Frame = +3 Query: 234 DLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPLLNEN---ARVVN 404 ++D R+ L + + + +++ + L+ N+YG + + PLL ++ AR+VN Sbjct: 179 NIDPRVWLSGKAVNLIQSVIVQTYDEAVKCLNTNYYGLKWITEALLPLLKQSPSGARIVN 238 Query: 405 VSGPAGLLATIENEDIRKRISDPTL-TEDELVALIQEYEHAARRGVEKTEGWG--MNVHA 575 + L I NE +R + + + E + A++ E+ + + GW + ++ Sbjct: 239 TTSLRSELKRIPNEKLRDELRNIDIWDEARIEAMLNEFLLDLKNERLEEAGWPTMLPAYS 298 Query: 576 VSKVALNAVT 605 +SK +N T Sbjct: 299 MSKTVVNLYT 308 >UniRef50_A7RNF1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 296 Score = 37.5 bits (83), Expect = 0.28 Identities = 32/158 (20%), Positives = 67/158 (42%), Gaps = 8/158 (5%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNI--LKSLERPDIEISYLQMDI 191 VA+V G +GY+ + L + I + A I LK E+PD + Y+ +D+ Sbjct: 17 VAIVTGGNCGIGYETARGLIRSGMTVIMGCRSEKAAESAIQHLKD-EQPDARVRYIHLDL 75 Query: 192 TYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 371 + S+ + ++++L+N + + + + + +G+ L+ Sbjct: 76 SDLSSVREFVKSFHQSENQLNVLVNNAGVMLTPYALTKDGFEQQIGICHFGHFLLTMLLL 135 Query: 372 PLLNE------NARVVNVSGPAGLLATIENEDIRKRIS 467 L + ++R+V VS A +I ED++ + S Sbjct: 136 DTLKKSGTKDCHSRIVTVSSTAHSSGSINFEDLQSKKS 173 >UniRef50_A2TIR8 Cluster: Receptor for egg jelly protein 9; n=9; cellular organisms|Rep: Receptor for egg jelly protein 9 - Strongylocentrotus purpuratus (Purple sea urchin) Length = 2965 Score = 37.5 bits (83), Expect = 0.28 Identities = 19/62 (30%), Positives = 35/62 (56%) Frame = +1 Query: 28 SSAPQATSDTKS*KNSQRLTKEKSTSLQKMTQPASTSSRAWRGPTSKSATCKWTSRIQRA 207 SS+ ++ + S +S + S+S + P+S+SS +W P+S S++ W+SR + Sbjct: 176 SSSSSSSGSSLSSSSSSSWSSPSSSSSSSWSSPSSSSSSSWSSPSSSSSS-SWSSRSSSS 234 Query: 208 SS 213 SS Sbjct: 235 SS 236 >UniRef50_A2R494 Cluster: Contig An14c0200, complete genome; n=1; Aspergillus niger|Rep: Contig An14c0200, complete genome - Aspergillus niger Length = 319 Score = 37.5 bits (83), Expect = 0.28 Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 3/96 (3%) Frame = +3 Query: 132 NILKSLERPDIEISYLQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEK 311 N +K+ E PD L +D++ +S+ R + + ER+D LIN +A + E Sbjct: 67 NAIKA-ETPDANTRLLIIDLSSQESVRRAAAEVNNYPERLDHLINNAGIMAAPYSTTPEG 125 Query: 312 IRRTLSVNFYGYINFGKLVYPLL---NENARVVNVS 410 + +N G+ F L+ + RVVNVS Sbjct: 126 VELQFGINHIGHFLFTNLLLEKIMSGESKVRVVNVS 161 >UniRef50_A3H6D0 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caldivirga maquilingensis IC-167|Rep: Short-chain dehydrogenase/reductase SDR - Caldivirga maquilingensis IC-167 Length = 278 Score = 37.5 bits (83), Expect = 0.28 Identities = 26/102 (25%), Positives = 46/102 (45%), Gaps = 4/102 (3%) Frame = +3 Query: 132 NILKSLERPDIEISYLQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLS--NF 305 N L L IE D+ ++++LR I+ R+D+L+N +K ++ Sbjct: 50 NALNYLRGRGIEPILFLGDVADRGNVVKLRDLIEGECGRLDVLVNNASIEVDKPFEDYDY 109 Query: 306 EKIRRTLSVNFYGYINFGKLVYPLL--NENARVVNVSGPAGL 425 E RR + VN Y + + PL+ E ++N+S G+ Sbjct: 110 ETWRRLIEVNLDAYYMLARELLPLIIKGEGKVIINISSVQGV 151 >UniRef50_A3J2Q4 Cluster: Short-chain dehydrogenase; n=2; Flavobacteriales|Rep: Short-chain dehydrogenase - Flavobacteria bacterium BAL38 Length = 274 Score = 37.1 bits (82), Expect = 0.37 Identities = 37/144 (25%), Positives = 65/144 (45%), Gaps = 4/144 (2%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMD 188 M L+ GAA +G Q L KG T + LK P+I+ ++D Sbjct: 1 MKKTVLITGAAGGIGKQTA--LFFADKGWNVIATMLSLEEADDLKF--HPNIQC--YELD 54 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINI--TDYVAEKNLSNFEKIRRTLSVNFYGYINFGK 362 + T SI + I +++ID++IN Y + LS KI +++N+ G + + Sbjct: 55 VISTISISNAKDAILKNNKKIDVIINNAGVGYRSFVELSEDSKINDIVAINWLGVVKICR 114 Query: 363 LVYPLL--NENARVVNVSGPAGLL 428 PL ++ + +N++ AGL+ Sbjct: 115 AFIPLFRAQKSGQFINITSVAGLV 138 >UniRef50_A2BY70 Cluster: Short-chain dehydrogenase/reductase (SDR) superfamily; n=7; Prochlorococcus marinus|Rep: Short-chain dehydrogenase/reductase (SDR) superfamily - Prochlorococcus marinus (strain MIT 9515) Length = 309 Score = 37.1 bits (82), Expect = 0.37 Identities = 32/135 (23%), Positives = 59/135 (43%), Gaps = 4/135 (2%) Frame = +3 Query: 27 VVGAASNLGYQVLKKLTETHKGKIYF--TTEDDTAGFNILKSLERPDIEISYLQMDITYT 200 + GA S LGY K L E + + T E + + LKSL P+ + + +++D+ Sbjct: 28 ITGANSGLGYYTAKALAEKNAHVVLACRTLEKANSALHKLKSLN-PEGKFTPIELDLADL 86 Query: 201 KSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPLL 380 + + I E++DLLIN + + + +VN ++ PL+ Sbjct: 87 NKVSEIGSKISTEFEKLDLLINNAGIMHPPKTLSPQGFEIQFAVNHLAHMLLTLKFLPLI 146 Query: 381 --NENARVVNVSGPA 419 + +R+V V+ A Sbjct: 147 EKQKGSRIVTVTSGA 161 >UniRef50_A1BFG5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Chlorobium phaeobacteroides DSM 266|Rep: Short-chain dehydrogenase/reductase SDR - Chlorobium phaeobacteroides (strain DSM 266) Length = 250 Score = 37.1 bits (82), Expect = 0.37 Identities = 23/137 (16%), Positives = 60/137 (43%), Gaps = 2/137 (1%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 +A+V G +G + L E+ + + ++ ++I+ + D+++ Sbjct: 8 IAVVTGGTRGIGRAISLHLAESGARVLALYARSRKSAESLEHEAAVRGLDITTFRGDLSH 67 Query: 198 TKSIIRLRHYIQDLDERIDLLIN-ITDYVAEKNLSNFEK-IRRTLSVNFYGYINFGKLVY 371 +S I++ + D E +D+L++ V K + +K ++ T +NF+ + + Sbjct: 68 EESFIQVVQQLHDSCEHVDILVHSAASGVHRKAMELSDKQLKWTFEINFFAVHRLTRELI 127 Query: 372 PLLNENARVVNVSGPAG 422 + R++ ++ P G Sbjct: 128 GKMGRGGRIIGITSPGG 144 >UniRef50_A0Z5P1 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; marine gamma proteobacterium HTCC2080|Rep: Short-chain dehydrogenase/reductase SDR - marine gamma proteobacterium HTCC2080 Length = 278 Score = 37.1 bits (82), Expect = 0.37 Identities = 27/118 (22%), Positives = 53/118 (44%), Gaps = 5/118 (4%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQ 182 D C ALV GAA +G K L+ H K+ T ++ A ++ + E Sbjct: 14 DGTCRTALVTGAAGGIGSATAKALS-NHGAKVMVTDVNEAALSALVDEIRAEGGEAMAAA 72 Query: 183 MDITYTKSIIRLRHYIQDLDERIDLLIN-----ITDYVAEKNLSNFEKIRRTLSVNFY 341 +D+ +S + R + D + +L+N + VA+ +L++++++ R S + Sbjct: 73 LDVGDPESWQQARQQVFDSWGPLSILVNNAGIDVVKSVADTSLADWDRLFRVNSTGMF 130 >UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacteria|Rep: Cyclopentanol dehydrogenase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 355 Score = 37.1 bits (82), Expect = 0.37 Identities = 32/141 (22%), Positives = 60/141 (42%), Gaps = 4/141 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VAL+ G A G + +L H +Y + G + L ++ + +D+T Sbjct: 103 VALITGGARGQG-EAEARLFAQHGAHVYICDVLEEEGEKLAAELRGSGLQADFRFLDVTD 161 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSN--FEKIRRTLSVNFYGYINFGKLVY 371 + R +I R+D+LIN L++ E+ R ++VN G + + Sbjct: 162 AEQWSRTVAHIDAGAGRLDVLINNAGINVRHQLTDTTSEEWDRIVAVNTKGQMLGMQACA 221 Query: 372 PLLNE--NARVVNVSGPAGLL 428 PL+ N ++N+ AG++ Sbjct: 222 PLMKRSGNGSIINIGSTAGIM 242 >UniRef50_Q9XVS9 Cluster: Putative uncharacterized protein dhs-22; n=2; Caenorhabditis|Rep: Putative uncharacterized protein dhs-22 - Caenorhabditis elegans Length = 333 Score = 37.1 bits (82), Expect = 0.37 Identities = 30/137 (21%), Positives = 63/137 (45%), Gaps = 6/137 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIE---ISYLQMD 188 VA+V G+ +G++ +++L K +Y + + L R + + +++ D Sbjct: 48 VAVVTGSNCGIGFETVRELN-LRKADVYMLCRSEEKANEAKRMLVRQGCDATRLHFIECD 106 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVAE-KNLSNFEKIRRTLSVNFYGYINFGKL 365 +T +S+ R + + ID+LIN + + K+ + +T N G +L Sbjct: 107 LTDFESVRRAAKETLESTDTIDILINNAGIMFQSKHEQTKDGHEKTWQSNHLGPFLLTEL 166 Query: 366 VYPLLNEN--ARVVNVS 410 P + ++ AR++NVS Sbjct: 167 FLPAVKKSSYARIINVS 183 >UniRef50_Q4QHL1 Cluster: Dehydrogenase-like protein; n=3; Leishmania|Rep: Dehydrogenase-like protein - Leishmania major Length = 412 Score = 37.1 bits (82), Expect = 0.37 Identities = 33/145 (22%), Positives = 67/145 (46%), Gaps = 4/145 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLER-PDIEISYLQMDIT 194 V ++ G +G +V+ +L I + A I + R + + ++++D+ Sbjct: 114 VVVITGGERGIGKEVVHQLLREGVDVILCCPFEAEALRTIARLKARVSNSRVHFVKLDLN 173 Query: 195 YTKSIIRLRHYIQDLDERIDLLINITDYVAE-KNLSNFEKIRRTLSVNFYGYINFGKLVY 371 +S+ + + RID+LIN + V+ + N LS+NF G++ F +L+ Sbjct: 174 DEESVRECAAEVLGMTPRIDVLINNSGLVSPLSHKLNKRGYEVVLSINFLGHVLFTELLL 233 Query: 372 PLLNEN--ARVVNVSGPAGLLATIE 440 + + +R+VNV+ L A +E Sbjct: 234 ERVKASGPSRIVNVASLMHLDACVE 258 >UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methanobrevibacter smithii ATCC 35061|Rep: Short chain dehydrogenase - Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) Length = 269 Score = 37.1 bits (82), Expect = 0.37 Identities = 26/92 (28%), Positives = 44/92 (47%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 +A+V G+ S +G + K L K+ + G ++ ++ + E SY DIT Sbjct: 10 IAIVTGSTSGIGIGIAK-LYAAEGAKVVICGRREEKGQAVVDNITKEGGESSYHFFDITN 68 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKN 293 T SI +L + +ID+L+N VA K+ Sbjct: 69 TNSIEKLIDDTAEKYGKIDILVNNAANVALKD 100 >UniRef50_P50162 Cluster: Tropinone reductase 1; n=77; Viridiplantae|Rep: Tropinone reductase 1 - Datura stramonium (Jimsonweed) (Common thornapple) Length = 273 Score = 37.1 bits (82), Expect = 0.37 Identities = 31/142 (21%), Positives = 63/142 (44%), Gaps = 5/142 (3%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYT 200 ALV G + +GY ++++L ++Y + ++ L+ + + D+ Sbjct: 24 ALVTGGSKGIGYAIVEELAGL-GARVYTCSRNEKELDECLEIWREKGLNVEGSVCDLLSR 82 Query: 201 KSIIRLRHYIQDL-DERIDLLINITDYVAEKNLSNF-EK-IRRTLSVNFYGYINFGKLVY 371 +L + + D ++++L+N V K +F EK + NF + ++ Y Sbjct: 83 TERDKLMQTVAHVFDGKLNILVNNAGVVIHKEAKDFTEKDYNIIMGTNFEAAYHLSQIAY 142 Query: 372 PLL--NENARVVNVSGPAGLLA 431 PLL ++N V+ +S AG A Sbjct: 143 PLLKASQNGNVIFLSSIAGFSA 164 >UniRef50_UPI000023F261 Cluster: hypothetical protein FG04592.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG04592.1 - Gibberella zeae PH-1 Length = 349 Score = 36.7 bits (81), Expect = 0.49 Identities = 22/88 (25%), Positives = 44/88 (50%), Gaps = 5/88 (5%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSL--ERPDI---EISYLQ 182 VA+V G + +GY +K L + K+Y ++ +K L E P I + +L+ Sbjct: 55 VAVVTGGNAGIGYYTVKHLA-SRGAKVYLGARSESRAKAAIKRLLEENPLIPQENVVWLR 113 Query: 183 MDITYTKSIIRLRHYIQDLDERIDLLIN 266 +D+ ++ +Q ++R+D+L+N Sbjct: 114 LDLANQSQVVDAAVELQSKEQRLDILVN 141 >UniRef50_Q2YCW1 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Nitrosospira multiformis ATCC 25196|Rep: Short-chain dehydrogenase/reductase SDR precursor - Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849) Length = 272 Score = 36.7 bits (81), Expect = 0.49 Identities = 35/134 (26%), Positives = 59/134 (44%), Gaps = 4/134 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 +ALV GA+S +G + L + G F ++S ER I + +D+T Sbjct: 5 IALVTGASSGIGRATAELLAQN--GYYVFAIARRKYRLEQIRS-ER----IEPIILDVTD 57 Query: 198 TKSIIRLRHYIQDLDERIDLLINIT--DYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 371 +++ + Y+ RIDLL+N + E R L VN +GY F + V Sbjct: 58 DEAVRKAIGYVISTKSRIDLLVNNAGISQLGAVECVPLEAARYQLEVNLFGYARFMQAVL 117 Query: 372 PLL--NENARVVNV 407 P + ++ +VN+ Sbjct: 118 PHMRNQKSGCIVNI 131 >UniRef50_Q9RBP5 Cluster: 1-hydroxy-2-glutathionyl-2-methyl-3-butene dehydrogenase; n=1; Rhodococcus sp. AD45|Rep: 1-hydroxy-2-glutathionyl-2-methyl-3-butene dehydrogenase - Rhodococcus sp. AD45 Length = 226 Score = 36.7 bits (81), Expect = 0.49 Identities = 22/84 (26%), Positives = 44/84 (52%), Gaps = 2/84 (2%) Frame = +3 Query: 183 MDITYTKSIIRLRHYIQDLDERIDLLINITD--YVAEKNLSNFEKIRRTLSVNFYGYINF 356 +D+T +S+ L + + ++D + ++ ++ E +++ IRR + +N G + Sbjct: 50 VDVTSQESVEALAARLSEKGVKLDAVFHVAGVMWLDEVGSLDYDLIRRQIEINTLGPLRT 109 Query: 357 GKLVYPLLNENARVVNVSGPAGLL 428 + V PLLNE A+V V+ G L Sbjct: 110 IEAVRPLLNEGAKVGIVTSRVGSL 133 >UniRef50_A1TDV9 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1) Length = 338 Score = 36.7 bits (81), Expect = 0.49 Identities = 33/154 (21%), Positives = 63/154 (40%), Gaps = 5/154 (3%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLER---PDIEIS 173 D ++ GA+S LG + + L + G + A + ++ R PD +S Sbjct: 37 DLSGKTCVITGASSGLGRESARALAKA--GAHVILAARNAAAMSETEAWLRAQLPDALLS 94 Query: 174 YLQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYIN 353 + +D+T SI I +L + +L+N + + N G+ Sbjct: 95 VVDLDLTSLASIAAAAAEISELTPVVHVLMNNAGVMFTPFGRTVDGFEIQFGTNHLGHFE 154 Query: 354 FGKLVYPLL--NENARVVNVSGPAGLLATIENED 449 +L++P L + ARVVN+S + ++ +D Sbjct: 155 LTRLLFPALVAADGARVVNLSSEGHRMGDVDFDD 188 >UniRef50_P37059 Cluster: Estradiol 17-beta-dehydrogenase 2; n=16; Mammalia|Rep: Estradiol 17-beta-dehydrogenase 2 - Homo sapiens (Human) Length = 387 Score = 36.7 bits (81), Expect = 0.49 Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 6/139 (4%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 203 LV G LG+ + K L E ++ G L+ P +S LQMDIT Sbjct: 86 LVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSP--RLSVLQMDITKPV 143 Query: 204 SIIRLRHYIQDL--DERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 I + + D + +IN + + + L ++ ++VNF+G + K Sbjct: 144 QIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTF 203 Query: 369 YPLLNEN-ARVVNVSGPAG 422 PLL ++ R+VNVS G Sbjct: 204 LPLLRKSKGRLVNVSSMGG 222 >UniRef50_UPI000155BF31 Cluster: PREDICTED: similar to double substrate-specificity short chain dehydrogenase/reductase 2, partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to double substrate-specificity short chain dehydrogenase/reductase 2, partial - Ornithorhynchus anatinus Length = 408 Score = 36.3 bits (80), Expect = 0.65 Identities = 34/150 (22%), Positives = 64/150 (42%), Gaps = 4/150 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSL--ERPDIEISYLQMDI 191 VA++ GA + +G + + L ++ D G + + E + ++ ++D+ Sbjct: 10 VAVITGANTGIGKETARDLAR-RGARVIIACRDVLKGESAAGEIRAETGNRQVLVRKLDL 68 Query: 192 TYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 371 TKSI ++++ +LIN + + L VN G+ L+ Sbjct: 69 ADTKSIRAFADRFLAEEKQLHILINNAGVMMCPYSKTADGFEMHLGVNHLGHFLLTHLLL 128 Query: 372 PLLNENA--RVVNVSGPAGLLATIENEDIR 455 L E+A RVVNVS A ++ I D++ Sbjct: 129 GRLKESAPARVVNVSSLAHIIGKIRFHDLQ 158 >UniRef50_UPI000069F00A Cluster: Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-HSD 2) (Microsomal 17-beta-hydroxysteroid dehydrogenase) (20 alpha- hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH).; n=1; Xenopus tropicalis|Rep: Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-HSD 2) (Microsomal 17-beta-hydroxysteroid dehydrogenase) (20 alpha- hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH). - Xenopus tropicalis Length = 388 Score = 36.3 bits (80), Expect = 0.65 Identities = 36/139 (25%), Positives = 60/139 (43%), Gaps = 6/139 (4%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 203 L+ G S G+ + K L + G F D G + + +Q++IT + Sbjct: 90 LITGCDSGFGHALAKHLDKL--GVHVFAGVLDKKGPGAEELKRVCSTHLCLIQLNITNCE 147 Query: 204 SIIR----LRHYIQDLDE-RIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 I + + YIQD I + YVA+ L F R+ + VNF G + ++ Sbjct: 148 EIRKAYKEISSYIQDAGLWGIVHNAGVLGYVADGELIPFSVYRQCMEVNFLGAVQVTQIF 207 Query: 369 YPLLNEN-ARVVNVSGPAG 422 PLL ++ R+V++S G Sbjct: 208 APLLRKSKGRLVSISSMGG 226 >UniRef50_Q8F0Y4 Cluster: Sensor protein; n=3; Leptospira|Rep: Sensor protein - Leptospira interrogans Length = 712 Score = 36.3 bits (80), Expect = 0.65 Identities = 17/41 (41%), Positives = 26/41 (63%), Gaps = 1/41 (2%) Frame = +3 Query: 33 GAASNLGYQVLKKLTETHKGKIYF-TTEDDTAGFNILKSLE 152 GA + LG + +++ E H GKIYF T+++ T F IL + E Sbjct: 658 GAGTGLGLDICRRIIEDHNGKIYFETSKEGTTFFVILPASE 698 >UniRef50_Q7VAC7 Cluster: Light dependent protochlorophyllide oxido-reductase; n=13; Cyanobacteria|Rep: Light dependent protochlorophyllide oxido-reductase - Prochlorococcus marinus Length = 315 Score = 36.3 bits (80), Expect = 0.65 Identities = 35/146 (23%), Positives = 62/146 (42%), Gaps = 3/146 (2%) Frame = +3 Query: 27 VVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDI-EISYLQMDITYTK 203 V GA S LG+ + L E I + A + K L+ D +I L++D+ + Sbjct: 18 VTGANSGLGFDTAQALLEKGATVILGCRTLEKAERSRQKLLDETDCGKIDVLEIDLADLE 77 Query: 204 SIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPLL- 380 + I +++DLLIN +A + + +VN ++ + PL+ Sbjct: 78 KVNEALDKIAVKYKKLDLLINNAGVMAPPQTFSKQGFELQFAVNHLSHMALTLKLLPLIA 137 Query: 381 -NENARVVNVSGPAGLLATIENEDIR 455 +RVV VS A + I +D++ Sbjct: 138 KQPGSRVVTVSSGAQYMGKINLDDLQ 163 >UniRef50_Q7D3F2 Cluster: AGR_pAT_417p; n=5; Alphaproteobacteria|Rep: AGR_pAT_417p - Agrobacterium tumefaciens (strain C58 / ATCC 33970) Length = 310 Score = 36.3 bits (80), Expect = 0.65 Identities = 35/143 (24%), Positives = 61/143 (42%), Gaps = 6/143 (4%) Frame = +3 Query: 156 PDIEISYLQMDITYTKSIIRLRHYIQDLDERIDLLINITD-YVAEKNLSNFEKIRRTLSV 332 P + +S+ ++D+ SI +++ E +DLL+N V K + Sbjct: 71 PHVTVSFEKLDLADLTSIALFAQRMENDRESLDLLVNNAGIMVPPKRQETRDGFELQFGT 130 Query: 333 NFYGYINFGKLVYPLLNE--NARVVNVSGPAGLLATIENEDIR-KRISDP--TLTEDELV 497 N+ G+ + PLL + +ARVV VS A I DI ++ P ++ +L Sbjct: 131 NYLGHFALTAHLMPLLKKGTDARVVTVSSVAARAGKINFADINSEKNYHPMRAYSQSKLA 190 Query: 498 ALIQEYEHAARRGVEKTEGWGMN 566 L+ E R + GWG++ Sbjct: 191 CLMFALELQDR---SRAAGWGVS 210 >UniRef50_A6GH96 Cluster: Putative short-chain dehydrogenase/reductase; n=1; Plesiocystis pacifica SIR-1|Rep: Putative short-chain dehydrogenase/reductase - Plesiocystis pacifica SIR-1 Length = 264 Score = 36.3 bits (80), Expect = 0.65 Identities = 30/141 (21%), Positives = 58/141 (41%), Gaps = 7/141 (4%) Frame = +3 Query: 21 ALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYT 200 ALV G + +LG + +L + I A ++ ++ R D +Q D+ T Sbjct: 19 ALVTGGSRSLGKDIALRLAQAGADVISTYRSQSEAAAEVVDAITRLDRRAVAVQADLEGT 78 Query: 201 KSIIRLRH-YIQDLD----ERIDLLINITDYVAEKNLSNF--EKIRRTLSVNFYGYINFG 359 I L + L E +D+L+N + + + ++ R ++ NF + Sbjct: 79 GQIAALAEAVVAQLASWGAEGLDILVNNAGVSSHQPFGSITEDEFDRVVNTNFKSVVFLT 138 Query: 360 KLVYPLLNENARVVNVSGPAG 422 + + P LN+ RV+ + G Sbjct: 139 QALLPTLNDGGRVIAIGSGLG 159 >UniRef50_A6CW76 Cluster: Putative short chain dehydrogenase; n=1; Vibrio shilonii AK1|Rep: Putative short chain dehydrogenase - Vibrio shilonii AK1 Length = 270 Score = 36.3 bits (80), Expect = 0.65 Identities = 32/145 (22%), Positives = 63/145 (43%), Gaps = 5/145 (3%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLK-KLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQM 185 M LV G AS +G ++ + E K I + D A + + + +I Q+ Sbjct: 5 MNKTVLVTGGASGMGKAYVELAVAEGAKTVIIWDLNQD-AMEQVKQEFHNSETQIYTFQV 63 Query: 186 DITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFE--KIRRTLSVNFYGYINFG 359 D+T T+ + + I ++LLIN V ++ + + KI ++ +N ++ Sbjct: 64 DVTDTQLVYQTAEIILKNIGAVELLINNAGIVVSEHFIDHDPRKIDLSMQINSTAPMHIA 123 Query: 360 KLVYPLLNE--NARVVNVSGPAGLL 428 + P + E +VN++ AG + Sbjct: 124 RAFLPAMAEVNEGHIVNIASGAGFM 148 >UniRef50_A1ETE0 Cluster: Inner membrane transport protein YdhC; n=1; Vibrio cholerae V52|Rep: Inner membrane transport protein YdhC - Vibrio cholerae V52 Length = 133 Score = 36.3 bits (80), Expect = 0.65 Identities = 18/54 (33%), Positives = 33/54 (61%), Gaps = 3/54 (5%) Frame = +3 Query: 453 RKRISD-PTLTEDELVALIQEYEHAARRGVEKTEGWGM--NVHAVSKVALNAVT 605 RK + D LTE+++ ++Q + H ++ + GW M V+++SK++LNA T Sbjct: 16 RKELGDIENLTEEKIDGILQNFLHDLKQDALEVNGWQMIGPVYSISKLSLNAYT 69 >UniRef50_A0B1Z9 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Burkholderia cenocepacia|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia cenocepacia (strain HI2424) Length = 301 Score = 36.3 bits (80), Expect = 0.65 Identities = 36/159 (22%), Positives = 67/159 (42%), Gaps = 6/159 (3%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTED---DTAGFNILKSLERPDIEISYLQMDIT 194 ++ GA S G + ++L I + D A +I K IE+ L D++ Sbjct: 13 VITGANSGTGKEATRRLVAAGADVIMAVRSESKGDAARRDIRKEFPGTSIEVRTL--DLS 70 Query: 195 YTKSIIRLRHYIQDLDERIDLLINITDYVAEKN-LSNFEKIRRTLSVNFYGYINFGKLVY 371 S+ + + +D+L+N + + + + L+ NF G+ L+ Sbjct: 71 SLASVRNFGRQLLEEGRPLDVLVNNAGIMMPPTRVLSSDGFELQLATNFLGHFALTNLLL 130 Query: 372 PLLNE--NARVVNVSGPAGLLATIENEDIRKRISDPTLT 482 PLL E + RV ++ A + ATI +D++ S +T Sbjct: 131 PLLLEAKSPRVATMTSSAAMGATINFDDLQGERSYKPMT 169 >UniRef50_A6SEL1 Cluster: Putative uncharacterized protein; n=2; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 292 Score = 36.3 bits (80), Expect = 0.65 Identities = 26/130 (20%), Positives = 52/130 (40%), Gaps = 6/130 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLE--RPDIEISYLQMDI 191 V ++GA+S +G + + + + + + + + + P + DI Sbjct: 28 VVCIIGASSGIGEHIAYSFAQAGASGVLLASRNTSELTRVAEKIRVISPKTRVEIFSCDI 87 Query: 192 TYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEK----IRRTLSVNFYGYINFG 359 T + +I L +YI++ R+D+ I + Y L E + +N G N Sbjct: 88 TSSSNISDLANYIKETFGRLDVCIPNSGYAGPVTLRVTEGDPAWFQENFDINMIGTYNCA 147 Query: 360 KLVYPLLNEN 389 + PLL E+ Sbjct: 148 HYLIPLLLES 157 >UniRef50_Q8NBN7 Cluster: Retinol dehydrogenase 13; n=19; Deuterostomia|Rep: Retinol dehydrogenase 13 - Homo sapiens (Human) Length = 331 Score = 36.3 bits (80), Expect = 0.65 Identities = 34/147 (23%), Positives = 62/147 (42%), Gaps = 4/147 (2%) Frame = +3 Query: 24 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSL--ERPDIEISYLQMDITY 197 +V GA + +G Q +L G I D K + E + ++ +D+ Sbjct: 42 IVTGANTGIGKQTALELAR-RGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLDLAS 100 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPL 377 KSI I + +ER+D+LIN + + + + VN G+ L+ Sbjct: 101 LKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNLLLDK 160 Query: 378 LNENA--RVVNVSGPAGLLATIENEDI 452 L +A R++N+S A + I+ +D+ Sbjct: 161 LKASAPSRIINLSSLAHVAGHIDFDDL 187 >UniRef50_Q89AG9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=3; Gammaproteobacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Buchnera aphidicola subsp. Baizongia pistaciae Length = 245 Score = 36.3 bits (80), Expect = 0.65 Identities = 31/134 (23%), Positives = 59/134 (44%), Gaps = 4/134 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 +A++ GA LG + ++L+ T+ + T+ I K L+ I I ++DIT Sbjct: 7 IAVITGANRGLGKGIAEELSNTNNITVIGTSTSQKGCKIINKYLKNNGIGI---KLDITN 63 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNF--EKIRRTLSVNFYGYINFGKLVY 371 I + ++ R+D+LIN + +K L N + L+VN K V Sbjct: 64 PNEITKTMDFVYKNFGRVDILINNAGIIRDKLLINMKTQDWNSVLNVNLNSIFYMSKSVI 123 Query: 372 --PLLNENARVVNV 407 + N+ +++ + Sbjct: 124 RNMIKNKQGKIITI 137 >UniRef50_UPI000023F4AA Cluster: hypothetical protein FG10334.1; n=2; Gibberella zeae PH-1|Rep: hypothetical protein FG10334.1 - Gibberella zeae PH-1 Length = 926 Score = 35.9 bits (79), Expect = 0.86 Identities = 31/104 (29%), Positives = 50/104 (48%), Gaps = 5/104 (4%) Frame = +3 Query: 156 PDIEISYLQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVA---EKNLSNFEKIRRTL 326 P+ EI ++Q +++ + I+ + +DL+ T Y K+ + I +TL Sbjct: 137 PNAEIIWVQGEVSLLTDTKKACDVIKSRERSVDLVFLSTGYAPFTDRKDTTEGFDISQTL 196 Query: 327 SVNFYGYINFGKLVYPLLN--ENARVVNVSGPAGLLATIENEDI 452 +Y I F + PLLN E RVV+V G L+ I+ EDI Sbjct: 197 --RYYSRILFVLHLLPLLNAAEKPRVVSVGGGGMELSAIQLEDI 238 >UniRef50_Q73NW4 Cluster: Conserved domain protein; n=1; Treponema denticola|Rep: Conserved domain protein - Treponema denticola Length = 523 Score = 35.9 bits (79), Expect = 0.86 Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 2/54 (3%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLER--PDI 164 M L+ GA+ ++G +VLK++ ET K I + A + KSL++ PDI Sbjct: 1 MKKTILITGASGSMGSEVLKQIAETGKHDITIILREKKANIRLAKSLKKRYPDI 54 >UniRef50_Q0S4U3 Cluster: Dehydrogenase; n=2; Actinomycetales|Rep: Dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 284 Score = 35.9 bits (79), Expect = 0.86 Identities = 35/142 (24%), Positives = 58/142 (40%), Gaps = 4/142 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 V V G A +G +V ++L ++ D A L R + L++D+T Sbjct: 10 VIAVTGGARGIGREVARQLALAG-ARVAIGDVDGAAARRTADELGRAGGTVEGLELDVTD 68 Query: 198 TKSIIRLRHYIQDLDERIDLLINITD--YVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 371 T S ++D ID+L+N +V + R L+VN +G I +L Sbjct: 69 TASFAAFLTAVEDHWGLIDVLVNNAGVMWVGRFDEEPESATDRQLAVNLHGVIRGVRLAA 128 Query: 372 PLLNENAR--VVNVSGPAGLLA 431 P + R +V V+ A +A Sbjct: 129 PAMRARGRGQIVTVASLASKVA 150 >UniRef50_A0R7C5 Cluster: Oxidoreductase; n=3; Mycobacterium smegmatis|Rep: Oxidoreductase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 250 Score = 35.9 bits (79), Expect = 0.86 Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 2/123 (1%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VALV GA+S +G+ + L F ++ +ER ++D+T Sbjct: 10 VALVTGASSGIGWATARALAAEGATVAVFGRRLARLE-ELVDVIERDGGRAHAHEVDVTD 68 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNL--SNFEKIRRTLSVNFYGYINFGKLVY 371 ++ R I D RID+L+N ++A ++ RT+ VN G +N Sbjct: 69 GATVARSVQAIADEFGRIDILVNNAGFLANAPAVEADLADWHRTIDVNIGGVLNVTHAAL 128 Query: 372 PLL 380 PL+ Sbjct: 129 PLV 131 >UniRef50_Q109A3 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein, expressed; n=6; Oryza sativa|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein, expressed - Oryza sativa subsp. japonica (Rice) Length = 230 Score = 35.9 bits (79), Expect = 0.86 Identities = 28/140 (20%), Positives = 61/140 (43%), Gaps = 3/140 (2%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIE---IS 173 DA A+V GA+S +G + + L ++ + AG +++ R +I + Sbjct: 28 DARGLAAVVTGASSGIGLETTRVLA-LRGVRVVMAVRNVAAGHKAREAI-RAEIHGAIVH 85 Query: 174 YLQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYIN 353 L+MD++ S+ R L+ +++LIN +++ + + + + + N G+ Sbjct: 86 VLEMDLSSMDSVRRFASEFDSLNLPLNILINNAGILSKDCIRSIDGLELHFATNHIGHFL 145 Query: 354 FGKLVYPLLNENARVVNVSG 413 L+ + +R V G Sbjct: 146 LTNLLLENMKSTSRTTGVEG 165 >UniRef50_Q0CAF8 Cluster: Putative uncharacterized protein; n=1; Aspergillus terreus NIH2624|Rep: Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624) Length = 347 Score = 35.9 bits (79), Expect = 0.86 Identities = 30/139 (21%), Positives = 63/139 (45%), Gaps = 7/139 (5%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYF----TTEDDTAGFNIL-KSLERPDIEISYLQ 182 + ++ GA + +GY+ +K L ++ + F + E A L K + + LQ Sbjct: 6 IVVITGANTGIGYETVKALVQSDQAYRIFVGSRSVEKGEAAIETLRKEFPQSTSTLEVLQ 65 Query: 183 MDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGK 362 +D++ +SI ++ E ID+LIN + + + + ++N G Sbjct: 66 VDVSTDESIQHAFETVKAKTEYIDVLINNAGAAFDGQIGLRDCFNQAYNINVSGAHVMTY 125 Query: 363 LVYPLLNENA--RVVNVSG 413 + PLL ++A R++ ++G Sbjct: 126 IFMPLLLKSADPRLLFIAG 144 >UniRef50_P40580 Cluster: Uncharacterized oxidoreductase YIR036C; n=9; Saccharomycetales|Rep: Uncharacterized oxidoreductase YIR036C - Saccharomyces cerevisiae (Baker's yeast) Length = 263 Score = 35.9 bits (79), Expect = 0.86 Identities = 35/140 (25%), Positives = 60/140 (42%), Gaps = 7/140 (5%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMD 188 M V L+ GA+ +G Q++K + E I + AG L+ D + Y +D Sbjct: 1 MGKVILITGASRGIGLQLVKTVIEEDDECIVYGVARTEAGLQSLQREYGAD-KFVYRVLD 59 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLI---NITDYVAEKNLSNFE----KIRRTLSVNFYGY 347 IT + L I+ ++D ++ + + V + SN E + R VNF+ Sbjct: 60 ITDRSRMEALVEEIRQKHGKLDGIVANAGMLEPVKSISQSNSEHDIKQWERLFDVNFFSI 119 Query: 348 INFGKLVYPLLNENARVVNV 407 ++ L PLL + V N+ Sbjct: 120 VSLVALCLPLLKSSPFVGNI 139 >UniRef50_UPI000023E6D6 Cluster: hypothetical protein FG03303.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG03303.1 - Gibberella zeae PH-1 Length = 306 Score = 35.5 bits (78), Expect = 1.1 Identities = 26/130 (20%), Positives = 51/130 (39%), Gaps = 3/130 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIE---ISYLQMD 188 V L+ G S LG + ++L + KI+ + L+ + +S+L ++ Sbjct: 19 VILITGGNSGLGLESTRQLLKHDPAKIFLACRSKAKYDQAIAELQEQGSKTDAVSFLSLN 78 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 + +SI Q R+D+L+N + E + N G+ L+ Sbjct: 79 LASLESIKSAVRQFQQESTRLDVLLNNAGIMMTPEGLTEEGYEIQIGTNHMGHAFLTHLL 138 Query: 369 YPLLNENARV 398 P+L E ++ Sbjct: 139 LPVLEETTKI 148 >UniRef50_Q4S4S9 Cluster: Chromosome 2 SCAF14738, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 2 SCAF14738, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 283 Score = 35.5 bits (78), Expect = 1.1 Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 2/93 (2%) Frame = +3 Query: 180 QMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFG 359 Q+D++ KSI I ++R+D+LIN + + VN G+ Sbjct: 29 QLDLSSLKSIREFAEKITKEEQRVDVLINNAGVMRCPAWKTEDGFDMQFGVNHLGHFLLT 88 Query: 360 KLVYPLLNENA--RVVNVSGPAGLLATIENEDI 452 L+ L E+A RV+N++ A ++ ++ ED+ Sbjct: 89 NLLLDKLKESAPSRVINLASLAHIVGKMDFEDL 121 >UniRef50_Q986V1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n=2; Rhizobiales|Rep: 3-alpha-hydroxysteroid dehydrogenase - Rhizobium loti (Mesorhizobium loti) Length = 263 Score = 35.5 bits (78), Expect = 1.1 Identities = 26/84 (30%), Positives = 40/84 (47%) Frame = +3 Query: 171 SYLQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYI 350 S+++ DI+ + L + L +RID L N+ LS TL+VNF+G Sbjct: 47 SFVKADISSKAGVDEL---VARLPQRIDALCNVA------GLSGNTGAAATLAVNFFGLR 97 Query: 351 NFGKLVYPLLNENARVVNVSGPAG 422 + + P L E +VNV+ AG Sbjct: 98 ALSESLAPRLREGGAIVNVASIAG 121 >UniRef50_Q93HB3 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=1; Streptomyces avermitilis|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Streptomyces avermitilis Length = 246 Score = 35.5 bits (78), Expect = 1.1 Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 7/146 (4%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTET-HKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDIT 194 VALV GA+ LG V + L ++ +++T +D A + L P + D Sbjct: 10 VALVTGASGALGAAVARVLDHRGYRLALHYTNGEDQAR-KVAAKLSGPSTLVRADVADWA 68 Query: 195 YTKSII-RLRHYIQDLDERIDLLINITDYVAEKNLSNFEKI---RRTLSVNFYGYINFGK 362 T+ ++ R+R + I +L+N T + L + + RT++VN G + + Sbjct: 69 ATRDMVDRVRAELGG----ISVLVN-TGAIRRDGLMATQSVDDWTRTVAVNLIGTFHTCR 123 Query: 363 LVYP--LLNENARVVNVSGPAGLLAT 434 P L R++NV PAGLL + Sbjct: 124 AALPDMLRGRWGRIINVVSPAGLLGS 149 >UniRef50_Q8EUE2 Cluster: Short-chain alcohol dehydrogenase family enzyme; n=1; Mycoplasma penetrans|Rep: Short-chain alcohol dehydrogenase family enzyme - Mycoplasma penetrans Length = 272 Score = 35.5 bits (78), Expect = 1.1 Identities = 34/151 (22%), Positives = 70/151 (46%), Gaps = 6/151 (3%) Frame = +3 Query: 3 DAMCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQ 182 D++ V ++ GA+S +GY + K L+ H +T + F + D I Y++ Sbjct: 6 DSINKVVVITGASSGIGYAIGKYLSSKH-----YTVYSLSRQF-------KEDKYIRYIE 53 Query: 183 MDITYTKSIIRLRHYIQDLDERIDLLIN-----ITDYVAEKNLSNFEKIRRTLSVNFYGY 347 DIT + + + I IDL+IN IT + E +++ ++++ L VN Sbjct: 54 CDITNYEQVDDCLYTIFQKHNHIDLIINNSGFGITSAIEELDINKYQEM---LKVNVDAA 110 Query: 348 INFG-KLVYPLLNENARVVNVSGPAGLLATI 437 +N + + L + +++N+ A + ++ Sbjct: 111 LNLSIQAINYLKQSHGKIINMGSIASEIISL 141 >UniRef50_Q64PT9 Cluster: Putative oxidoreductase; n=7; Bacteroidales|Rep: Putative oxidoreductase - Bacteroides fragilis Length = 290 Score = 35.5 bits (78), Expect = 1.1 Identities = 29/133 (21%), Positives = 60/133 (45%), Gaps = 3/133 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKI---YFTTEDDTAGFNILKSLERPDIEISYLQMD 188 +A++ GA +G ++ + + I Y +++ +T ++K IE+ Q+D Sbjct: 6 LAVITGADGGMGTEITRAVACAGYDVIMACYSSSKAETKCRELVKETGNEKIEV--WQID 63 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 + S+ + + LL+N + + + RT+SVN+ G +L+ Sbjct: 64 LASLASVRAFADRMLRQKTPVALLMNNAGTMETGLHITEDGLERTVSVNYVGPYLLTRLL 123 Query: 369 YPLLNENARVVNV 407 PL+ E R+VN+ Sbjct: 124 LPLMGEGTRIVNM 136 >UniRef50_Q0R4G2 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reductase-like protein; n=3; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier-protein) reductase-like protein - Pseudomonas fluorescens Length = 245 Score = 35.5 bits (78), Expect = 1.1 Identities = 30/138 (21%), Positives = 56/138 (40%), Gaps = 4/138 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 VA+V G + +G ++ L + D+ A + ++ ++ LQ DI+ Sbjct: 5 VAVVTGGSRGIGRAIVLALAGAGYQVAFSYVRDEVAAMALRDEVQASGVDCLALQCDISR 64 Query: 198 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNF--EKIRRTLSVNFYGYINFGKLVY 371 SI ++ +R+DLL+N + L+ I + N G + + V Sbjct: 65 GDSIASFFERVEAHFQRVDLLVNNAGITRDGLLATMPASDILEVIQTNLVGTLLCCQQVL 124 Query: 372 P--LLNENARVVNVSGPA 419 P L + +VN+S A Sbjct: 125 PGMLRQRSGCIVNISSVA 142 >UniRef50_A6UZF9 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=16; Pseudomonas|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Pseudomonas aeruginosa PA7 Length = 266 Score = 35.5 bits (78), Expect = 1.1 Identities = 20/86 (23%), Positives = 39/86 (45%) Frame = +3 Query: 9 MCNVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMD 188 M AL+ GA+S +G + + L + I + D + +R +E+ + D Sbjct: 1 MPRYALITGASSGIGLALAEALARRGRALILVARQRDALESIAYELAQRFGVEVLFRTCD 60 Query: 189 ITYTKSIIRLRHYIQDLDERIDLLIN 266 + + L H ++ + +IDLL+N Sbjct: 61 LAEPLQLSGLLHELEQGERQIDLLVN 86 >UniRef50_A4T8M7 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium gilvum PYR-GCK Length = 301 Score = 35.5 bits (78), Expect = 1.1 Identities = 25/95 (26%), Positives = 43/95 (45%) Frame = +3 Query: 165 EISYLQMDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYG 344 + S +++D+ S+ R + D +D+LIN VA+ + TL NF G Sbjct: 67 DTSVVELDLADQSSV---RAFPSLFDGDVDVLINNAGAVAQHRTDTVDGFENTLGTNFLG 123 Query: 345 YINFGKLVYPLLNENARVVNVSGPAGLLATIENED 449 L+Y + +++VNV A A+I +D Sbjct: 124 PFALTNLLYGRV--RSKIVNVGSDAHKTASINFDD 156 >UniRef50_A3U149 Cluster: Short chain dehydrogenase; n=2; Proteobacteria|Rep: Short chain dehydrogenase - Oceanicola batsensis HTCC2597 Length = 527 Score = 35.5 bits (78), Expect = 1.1 Identities = 33/140 (23%), Positives = 59/140 (42%), Gaps = 3/140 (2%) Frame = +3 Query: 18 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 197 V +V GAA +G +L + + +G D G ++ +L L+ D + Sbjct: 9 VVIVTGAAGGIGRALLAEFSA--RGDRLIAV--DVPGSDLADALASLGARHHALECDQSD 64 Query: 198 TKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 368 I+ L I L +R+D+L+N I +A + + R ++ N G + Sbjct: 65 EAQILALYREIDALTDRVDVLVNNAAIGPTMAATTATPLSEFRHSIRTNTVGPFVMAREA 124 Query: 369 YPLLNENARVVNVSGPAGLL 428 ++E VVN + AG+L Sbjct: 125 ARRMHEGGVVVNTASLAGVL 144 >UniRef50_Q3LWJ0 Cluster: Putative uncharacterized protein; n=1; Bigelowiella natans|Rep: Putative uncharacterized protein - Bigelowiella natans (Pedinomonas minutissima) (Chlorarachnion sp.(strain CCMP 621)) Length = 709 Score = 35.5 bits (78), Expect = 1.1 Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 5/69 (7%) Frame = +3 Query: 252 DLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV----YPLLNENARVVN-VSGP 416 DLLI+ ++ N+SNF I N Y IN K+V YP+L E N +S Sbjct: 380 DLLIHKFKFMRVNNISNFNSIILVSRFNLYSIINVSKIVEIFEYPVLLEEYLTNNYISWS 439 Query: 417 AGLLATIEN 443 GL+ T ++ Sbjct: 440 KGLIVTTKH 448 >UniRef50_O16625 Cluster: Signal element on autosome protein 2; n=1; Caenorhabditis elegans|Rep: Signal element on autosome protein 2 - Caenorhabditis elegans Length = 1758 Score = 35.5 bits (78), Expect = 1.1 Identities = 16/67 (23%), Positives = 32/67 (47%), Gaps = 1/67 (1%) Frame = +2 Query: 50 RIPSLKKTHRDSQRKNLLHYRR*-HSRLQHPQEPGEARHRNQLLANGHHVYKEHHQTEAL 226 ++P L+ H Q+ +LH + + ++Q Q+ + + L HH + H Q + Sbjct: 1011 QLPPLQNPHNQQQQHQMLHQSQMNYQQVQQVQQVQHVQQQQNLQNQHHHQQQHHQQNQQQ 1070 Query: 227 HPGSRRK 247 PG+R + Sbjct: 1071 APGNRSR 1077 >UniRef50_Q5QP22 Cluster: RNA binding motif protein 39; n=20; Coelomata|Rep: RNA binding motif protein 39 - Homo sapiens (Human) Length = 193 Score = 35.5 bits (78), Expect = 1.1 Identities = 29/85 (34%), Positives = 39/85 (45%) Frame = +2 Query: 386 ER*SRKRVWTSWSSSHNRKRRYKKENQRSHIDRR*TGRFDPRIRTRRKKGSREDRRLGHE 565 ER +++ S S SH RKR KE +RS DR R + R R++ S+E RR Sbjct: 30 ERSKKRKKSKSRSRSHERKRSKSKERKRSR-DRE---RKKSKSRERKRSRSKERRRSRSR 85 Query: 566 CACREQSGIKRCNLSTAQGNGLIKG 640 R G R S + N I+G Sbjct: 86 SRDRRFRGRYRSPYSGPKFNSAIRG 110 >UniRef50_Q0V5R8 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 410 Score = 35.5 bits (78), Expect = 1.1 Identities = 38/144 (26%), Positives = 56/144 (38%) Frame = +2 Query: 158 RHRNQLLANGHHVYKEHHQTEALHPGSRRKDRFADKHHRLCGREEFI*FRKNPKNFER*L 337 R R NGH + + SR +D DK R RE +P++ Sbjct: 125 RGRGDRHRNGHRHRERSLDSRDQRHRSRSRDHGRDKRKREESRERSTRQSGHPESHRE-- 182 Query: 338 LRIHKLWEACVPATERER*SRKRVWTSWSSSHNRKRRYKKENQRSHIDRR*TGRFDPRIR 517 R H+ +ER R RK+ T SH R+R + + RS + R D + R Sbjct: 183 -RDHRRRHDTERDSERSRSQRKQKSTQ---SHKRRRSRSRSSSRSRSRSSHSTRTDKKRR 238 Query: 518 TRRKKGSREDRRLGHECACREQSG 589 R + S+ RR + R+ SG Sbjct: 239 YRSRSRSQSPRRPHRKNEDRKASG 262 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 661,628,554 Number of Sequences: 1657284 Number of extensions: 13710632 Number of successful extensions: 51860 Number of sequences better than 10.0: 390 Number of HSP's better than 10.0 without gapping: 48405 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 51458 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 50000004659 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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