Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30128
(710 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 171 2e-41
UniRef50_Q54CX6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 167 3e-40
UniRef50_A7UBP6 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 164 2e-39
UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to 3-hydroxyi... 164 2e-39
UniRef50_P28811 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 159 6e-38
UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella tul... 155 1e-36
UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase, mit... 150 3e-35
UniRef50_Q399N0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 146 6e-34
UniRef50_A1QPH6 Cluster: 3-hydroxyisobutyrate dehydrogenase mmsB... 142 6e-33
UniRef50_P63936 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 142 6e-33
UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 140 2e-32
UniRef50_Q9V8M5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 140 4e-32
UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 139 7e-32
UniRef50_A0JUJ6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 138 2e-31
UniRef50_Q0K0E2 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 137 2e-31
UniRef50_A0QSJ0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 136 4e-31
UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;... 136 7e-31
UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 132 6e-30
UniRef50_Q83D20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9... 131 1e-29
UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 131 2e-29
UniRef50_Q8ES28 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 129 8e-29
UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 129 8e-29
UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 129 8e-29
UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1; ... 128 1e-28
UniRef50_Q22B54 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 128 1e-28
UniRef50_Q9A8J9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 128 2e-28
UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 127 3e-28
UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 126 4e-28
UniRef50_Q1V2R0 Cluster: MmsB-like protein; n=2; Candidatus Pela... 126 4e-28
UniRef50_A3RRS1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 126 4e-28
UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=... 126 5e-28
UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 124 2e-27
UniRef50_Q9SUC0 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 124 2e-27
UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase... 124 3e-27
UniRef50_Q11FC5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 123 4e-27
UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 122 7e-27
UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 122 1e-26
UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep: ... 122 1e-26
UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogena... 121 2e-26
UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 121 2e-26
UniRef50_Q930C6 Cluster: Probable; n=8; Alphaproteobacteria|Rep:... 120 4e-26
UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 120 4e-26
UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 120 5e-26
UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2; ... 120 5e-26
UniRef50_A3SJ77 Cluster: Probable oxidoreductase; n=1; Roseovari... 119 6e-26
UniRef50_Q58PL4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 118 1e-25
UniRef50_A6SW62 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 117 2e-25
UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 117 3e-25
UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 116 4e-25
UniRef50_A2SP40 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 116 6e-25
UniRef50_A0GVR3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 115 1e-24
UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 115 1e-24
UniRef50_Q1QWQ5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 114 2e-24
UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 113 5e-24
UniRef50_A0C2T7 Cluster: Chromosome undetermined scaffold_145, w... 113 5e-24
UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep: Lin... 111 1e-23
UniRef50_Q7WCG3 Cluster: Putative uncharacterized protein; n=2; ... 111 1e-23
UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 111 2e-23
UniRef50_A0N0V2 Cluster: BtdhL; n=1; Azoarcus anaerobius|Rep: Bt... 110 3e-23
UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 110 4e-23
UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 109 5e-23
UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 109 5e-23
UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 109 7e-23
UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 108 1e-22
UniRef50_Q4KH51 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 107 2e-22
UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 107 2e-22
UniRef50_Q0LNZ7 Cluster: 3-hydroxyisobutyrate dehydrogenase prec... 107 3e-22
UniRef50_Q7WG50 Cluster: Probable oxidoreductase; n=1; Bordetell... 107 4e-22
UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 107 4e-22
UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 107 4e-22
UniRef50_Q89UN2 Cluster: Bll1384 protein; n=9; Bacteria|Rep: Bll... 106 5e-22
UniRef50_A2U9T6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 106 5e-22
UniRef50_Q1YHQ4 Cluster: Putative 2-hydroxy-3-oxopropionate redu... 106 6e-22
UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 105 1e-21
UniRef50_A0LMG6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9... 105 1e-21
UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase, pu... 105 1e-21
UniRef50_UPI00015B4162 Cluster: PREDICTED: similar to MGC108315 ... 104 2e-21
UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium tumef... 104 2e-21
UniRef50_A5USN9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 104 2e-21
UniRef50_A3VLN6 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 104 2e-21
UniRef50_A1B741 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 104 2e-21
UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 103 4e-21
UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 103 4e-21
UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 103 6e-21
UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep: Oxi... 102 8e-21
UniRef50_A0LTQ8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 102 8e-21
UniRef50_Q84H84 Cluster: Putative oxidoreductase; n=1; Arthrobac... 102 1e-20
UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme F420-depe... 102 1e-20
UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=... 101 2e-20
UniRef50_A5VEA3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 101 2e-20
UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-lik... 101 2e-20
UniRef50_A5VBF0 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 100 3e-20
UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase fam... 100 3e-20
UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 100 3e-20
UniRef50_A0FZ96 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 100 7e-20
UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 99 9e-20
UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep: Dehyd... 99 9e-20
UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme F420-depe... 99 1e-19
UniRef50_A3K497 Cluster: Probable 6-phosphogluconate dehydrogena... 99 1e-19
UniRef50_A0JXR2 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 99 1e-19
UniRef50_Q9L7S0 Cluster: Uncharacterized oxidoreductase yihU; n=... 99 1e-19
UniRef50_Q8EW87 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 98 2e-19
UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 98 2e-19
UniRef50_Q39MY1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 96 7e-19
UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=... 96 9e-19
UniRef50_Q0RCX7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 96 9e-19
UniRef50_A5P0V0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 96 9e-19
UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole gen... 95 1e-18
UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 95 2e-18
UniRef50_A1R2J4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 95 2e-18
UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1; ... 94 3e-18
UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 94 3e-18
UniRef50_Q0URA2 Cluster: Putative uncharacterized protein; n=1; ... 94 3e-18
UniRef50_A3JU55 Cluster: Predicted dehydrogenase, with NAD(P)-bi... 94 4e-18
UniRef50_Q4PCH4 Cluster: Putative uncharacterized protein; n=1; ... 94 4e-18
UniRef50_A1WM48 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 93 5e-18
UniRef50_Q1IQE6 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 93 6e-18
UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 93 6e-18
UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 93 8e-18
UniRef50_A1ZWM5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 93 8e-18
UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 93 8e-18
UniRef50_A0QUD5 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 92 1e-17
UniRef50_Q6C351 Cluster: Yarrowia lipolytica chromosome F of str... 91 2e-17
UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1; O... 91 2e-17
UniRef50_A0NRG5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 91 2e-17
UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 91 3e-17
UniRef50_Q2UHA9 Cluster: Predicted dehydrogenase; n=16; Pezizomy... 91 3e-17
UniRef50_A1UJF2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 90 4e-17
UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 90 6e-17
UniRef50_A0R1N4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 89 8e-17
UniRef50_A0GPK7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 89 8e-17
UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 89 1e-16
UniRef50_A5FTT0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 89 1e-16
UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=4... 89 1e-16
UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 89 1e-16
UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family prot... 89 1e-16
UniRef50_Q0FFH2 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 89 1e-16
UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 88 2e-16
UniRef50_A7DSF1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 88 2e-16
UniRef50_Q89M84 Cluster: Blr4309 protein; n=6; Bradyrhizobiaceae... 88 2e-16
UniRef50_Q1B326 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 88 2e-16
UniRef50_Q4WV01 Cluster: Oxidoreductase, acting on the CH-OH gro... 88 2e-16
UniRef50_Q7NR40 Cluster: Probable 3-hydroxyisobutyrate dehydroge... 87 3e-16
UniRef50_Q89RT2 Cluster: Bll2680 protein; n=1; Bradyrhizobium ja... 87 4e-16
UniRef50_Q3W9L4 Cluster: Putative uncharacterized protein; n=1; ... 87 4e-16
UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 87 4e-16
UniRef50_Q13PY3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 87 5e-16
UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1; ... 87 5e-16
UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 87 5e-16
UniRef50_A1CAY2 Cluster: Oxidoreductase, acting on the CH-OH gro... 87 5e-16
UniRef50_Q9JYH6 Cluster: 3-hydroxyacid dehydrogenase; n=5; Prote... 86 7e-16
UniRef50_Q8VYC5 Cluster: Fructose-bisphosphate aldolase; n=12; c... 86 7e-16
UniRef50_O33730 Cluster: Uncharacterized oxidoreductase Sfri_150... 86 7e-16
UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain... 86 9e-16
UniRef50_Q46TQ0 Cluster: UDP-glucose/GDP-mannose dehydrogenase:P... 86 9e-16
UniRef50_Q656T5 Cluster: Oxidoreductase-like; n=3; Oryza sativa|... 86 9e-16
UniRef50_A1WJN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 85 1e-15
UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 85 2e-15
UniRef50_A6G049 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 85 2e-15
UniRef50_Q3W3N3 Cluster: Putative uncharacterized protein; n=1; ... 85 2e-15
UniRef50_Q2CHC8 Cluster: Oxidoreductase; n=1; Oceanicola granulo... 84 3e-15
UniRef50_A2C1U6 Cluster: 3-hydroxyisobutyrate dehydrogenase and ... 84 3e-15
UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2; environm... 84 4e-15
UniRef50_Q2BFK1 Cluster: Oxidoreductase; n=1; Bacillus sp. NRRL ... 84 4e-15
UniRef50_Q019Z7 Cluster: Oxidoreductase-like; n=1; Ostreococcus ... 84 4e-15
UniRef50_Q7WNK6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 83 5e-15
UniRef50_Q1GF31 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 83 7e-15
UniRef50_A6VLT0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 83 7e-15
UniRef50_Q5FQ06 Cluster: Putative oxidoreductase; n=1; Gluconoba... 83 9e-15
UniRef50_Q0UVR9 Cluster: Putative uncharacterized protein; n=1; ... 82 2e-14
UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD b... 81 3e-14
UniRef50_A6VYD9 Cluster: 2-hydroxy-3-oxopropionate reductase pre... 81 3e-14
UniRef50_Q12H32 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 80 5e-14
UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 80 5e-14
UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1... 79 1e-13
UniRef50_A1GFG2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 79 1e-13
UniRef50_A3EW86 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 79 1e-13
UniRef50_P71825 Cluster: Uncharacterized oxidoreductase Rv0770/M... 78 2e-13
UniRef50_Q20XN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 78 2e-13
UniRef50_Q8PK98 Cluster: 3-hydroxyisobutirate dehydrogenase; n=3... 77 3e-13
UniRef50_Q9LM23 Cluster: Fructose-bisphosphate aldolase; n=2; Ar... 77 3e-13
UniRef50_Q0C8I2 Cluster: Predicted protein; n=3; Pezizomycotina|... 77 3e-13
UniRef50_Q9HLR4 Cluster: Putative uncharacterized protein Ta0161... 77 3e-13
UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus amyloliquefa... 77 6e-13
UniRef50_Q0BTJ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 77 6e-13
UniRef50_Q6F842 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 76 8e-13
UniRef50_O66454 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 76 8e-13
UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1; ... 76 8e-13
UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4; Bordetell... 76 1e-12
UniRef50_Q9LNP0 Cluster: F1L3.35; n=8; Magnoliophyta|Rep: F1L3.3... 76 1e-12
UniRef50_A7H7Z5 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 75 1e-12
UniRef50_A0JRK4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 75 1e-12
UniRef50_Q74D68 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 74 3e-12
UniRef50_A3LTC4 Cluster: 3-hydroxyisobutyrate dehydrogenase-like... 74 3e-12
UniRef50_A5P600 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 74 4e-12
UniRef50_A0YMN9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 74 4e-12
UniRef50_Q5LNV6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2... 73 5e-12
UniRef50_A7RG59 Cluster: Predicted protein; n=1; Nematostella ve... 73 5e-12
UniRef50_Q55JR1 Cluster: Putative uncharacterized protein; n=2; ... 73 5e-12
UniRef50_A5WG80 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 73 7e-12
UniRef50_A0GI22 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 73 7e-12
UniRef50_Q98K09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7... 73 9e-12
UniRef50_A1UJF3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 73 9e-12
UniRef50_A0R1N5 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 73 9e-12
UniRef50_Q4Q9Z1 Cluster: Dehydrogenase-like protein; n=6; Trypan... 73 9e-12
UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 72 1e-11
UniRef50_Q3WJ00 Cluster: 6-phosphogluconate dehydrogenase, NAD b... 72 1e-11
UniRef50_Q7Q161 Cluster: ENSANGP00000013149; n=11; Culicidae|Rep... 72 1e-11
UniRef50_A3H9B3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 72 1e-11
UniRef50_Q9RX16 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=6... 72 2e-11
UniRef50_Q7NEW9 Cluster: Glr3759 protein; n=3; Bacteria|Rep: Glr... 71 2e-11
UniRef50_Q21ZN3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 71 2e-11
UniRef50_Q033P2 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 71 2e-11
UniRef50_A7DWL2 Cluster: Putative dehydrogenase; n=1; Streptomyc... 71 3e-11
UniRef50_A3Y8R5 Cluster: Putative dehydrogenase; n=1; Marinomona... 71 3e-11
UniRef50_A0RU56 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 71 3e-11
UniRef50_A6R0U9 Cluster: Predicted protein; n=1; Ajellomyces cap... 70 5e-11
UniRef50_A6RMW8 Cluster: Putative uncharacterized protein; n=2; ... 70 7e-11
UniRef50_Q5GUM4 Cluster: Dehydrogenase; n=5; Gammaproteobacteria... 69 9e-11
UniRef50_Q0RIL5 Cluster: Putative uncharacterized protein; n=1; ... 69 9e-11
UniRef50_Q39KK8 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 69 1e-10
UniRef50_Q120Q9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 69 2e-10
UniRef50_Q1V2K7 Cluster: NADP oxidoreductase, coenzyme F420-depe... 68 2e-10
UniRef50_A1SQ87 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 68 2e-10
UniRef50_Q4WXG9 Cluster: 3-hydroxyisobutyrate dehydrogenase, put... 68 2e-10
UniRef50_Q9I1R8 Cluster: Probable dehydrogenase; n=7; Pseudomona... 68 3e-10
UniRef50_A0K107 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 68 3e-10
UniRef50_Q6RXW5 Cluster: Succinic semialdehyde dehydrogenase; n=... 67 3e-10
UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family... 67 5e-10
UniRef50_A3ET09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3... 67 5e-10
UniRef50_Q2JEN4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 66 6e-10
UniRef50_Q221W9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 66 8e-10
UniRef50_A0AWL7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 66 8e-10
UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 66 1e-09
UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4... 66 1e-09
UniRef50_A4FKN9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 65 2e-09
UniRef50_Q21ZT0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 64 2e-09
UniRef50_A1UDJ6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 64 2e-09
UniRef50_Q3W031 Cluster: Putative dehydrogenase; n=1; Frankia sp... 64 4e-09
UniRef50_Q01PV6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 63 7e-09
UniRef50_A3ES45 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 63 7e-09
UniRef50_A7I8V1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 62 1e-08
UniRef50_Q13VQ8 Cluster: Putative dehydrogenase/oxidoreductase p... 62 1e-08
UniRef50_A3Q3U7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 62 1e-08
UniRef50_A5CN67 Cluster: Putative beta-hydroxyacid dehydrogenase... 62 2e-08
UniRef50_Q19TN0 Cluster: 3-hydroxyisobutyrate dehydrogenase fami... 61 2e-08
UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogena... 61 2e-08
UniRef50_Q21AH6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 61 3e-08
UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23; A... 60 5e-08
UniRef50_Q8U2W2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 60 5e-08
UniRef50_Q8YRT5 Cluster: 3-hydroxyacid dehydrogenase; n=5; Cyano... 59 1e-07
UniRef50_Q1INE9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 59 1e-07
UniRef50_Q89GM2 Cluster: Bll6323 protein; n=6; Proteobacteria|Re... 58 2e-07
UniRef50_Q1GM24 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 58 2e-07
UniRef50_A3PRM1 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 58 3e-07
UniRef50_UPI0000D55E08 Cluster: PREDICTED: similar to CG4747-PA;... 57 4e-07
UniRef50_A1WEB7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 57 4e-07
UniRef50_Q9RU02 Cluster: 6-phosphogluconate dehydrogenase; n=24;... 57 5e-07
UniRef50_O66788 Cluster: 6-phosphogluconate dehydrogenase; n=2; ... 56 7e-07
UniRef50_A0VSV4 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 56 7e-07
UniRef50_Q1NHG5 Cluster: Putative uncharacterized protein; n=1; ... 55 2e-06
UniRef50_A4EEN1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 55 2e-06
UniRef50_A3PSD9 Cluster: 6-phosphogluconate dehydrogenase, decar... 55 2e-06
UniRef50_Q6KZX0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 55 2e-06
UniRef50_Q92P61 Cluster: 6-phosphogluconate dehydrogenase, decar... 55 2e-06
UniRef50_Q9K9H3 Cluster: 6-phosphogluconate dehydrogenase; n=7; ... 54 3e-06
UniRef50_A5FVG0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 54 3e-06
UniRef50_Q55W03 Cluster: Putative uncharacterized protein; n=2; ... 54 3e-06
UniRef50_Q3J9H5 Cluster: 6-phosphogluconate dehydrogenase, decar... 54 5e-06
UniRef50_Q220G7 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 53 6e-06
UniRef50_Q1NHF5 Cluster: Putative oxidoreductase; n=1; Sphingomo... 53 6e-06
UniRef50_Q0RMX6 Cluster: Putative reductase; n=1; Frankia alni A... 53 6e-06
UniRef50_A3H6C3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 53 8e-06
UniRef50_P80859 Cluster: 6-phosphogluconate dehydrogenase, decar... 52 1e-05
UniRef50_Q4WSB8 Cluster: 6-phosphogluconate dehydrogenase family... 52 1e-05
UniRef50_A6ELE2 Cluster: 6-phosphogluconate dehydrogenase, decar... 51 2e-05
UniRef50_Q5FU44 Cluster: Putative oxidoreductase; n=1; Gluconoba... 51 3e-05
UniRef50_A4JSC3 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 51 3e-05
UniRef50_A4BV63 Cluster: 3-hydroxyacid dehydrogenase; n=1; Nitro... 51 3e-05
UniRef50_Q6D9X4 Cluster: Putative 2-hydroxy-3-oxopropionate redu... 50 4e-05
UniRef50_Q5FHQ8 Cluster: 6-phosphogluconate dehydrogenase, decar... 50 4e-05
UniRef50_A0QZR7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 50 4e-05
UniRef50_Q9V8M5-2 Cluster: Isoform C of Q9V8M5 ; n=1; Drosophila... 50 7e-05
UniRef50_Q0U6Q6 Cluster: Putative uncharacterized protein; n=5; ... 50 7e-05
UniRef50_P54448 Cluster: Uncharacterized protein yqeC; n=13; Bac... 50 7e-05
UniRef50_P37754 Cluster: 6-phosphogluconate dehydrogenase, decar... 50 7e-05
UniRef50_Q9RBX6 Cluster: IgiB; n=1; Vogesella indigofera|Rep: Ig... 49 1e-04
UniRef50_A2BJA4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1... 49 1e-04
UniRef50_Q660W3 Cluster: 6-phosphogluconate dehydrogenase, decar... 48 3e-04
UniRef50_Q64V77 Cluster: 6-phosphogluconate dehydrogenase, decar... 48 3e-04
UniRef50_Q629W3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=... 47 5e-04
UniRef50_A1RWA6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 47 5e-04
UniRef50_Q836Q9 Cluster: 6-phosphogluconate dehydrogenase, decar... 46 7e-04
UniRef50_A4S5A4 Cluster: Predicted protein; n=2; Ostreococcus|Re... 46 7e-04
UniRef50_O34969 Cluster: Uncharacterized oxidoreductase yfjR; n=... 46 7e-04
UniRef50_Q17761 Cluster: 6-phosphogluconate dehydrogenase, decar... 46 0.001
UniRef50_A7CWR7 Cluster: 6-phosphogluconate dehydrogenase NAD-bi... 45 0.002
UniRef50_A0PKN6 Cluster: 6-phosphogluconate dehydrogenase, decar... 45 0.002
UniRef50_Q5MZU3 Cluster: 3-hydroxyacid dehydrogenase; n=3; Cyano... 44 0.003
UniRef50_Q53WI1 Cluster: Putative uncharacterized protein TTHB24... 44 0.003
UniRef50_A6T947 Cluster: Putative dehydrogenase; n=1; Klebsiella... 44 0.003
UniRef50_Q2UET7 Cluster: Predicted protein; n=7; Eurotiomycetida... 44 0.004
UniRef50_Q8TUC1 Cluster: Predicted protein; n=4; Methanosarcinac... 44 0.004
UniRef50_A0FZ97 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 43 0.006
UniRef50_P21577 Cluster: 6-phosphogluconate dehydrogenase, decar... 43 0.006
UniRef50_UPI0000EBE4FC Cluster: PREDICTED: hypothetical protein;... 43 0.009
UniRef50_P31072 Cluster: 6-phosphogluconate dehydrogenase, decar... 43 0.009
UniRef50_Q9CDN4 Cluster: 6-phosphogluconate dehydrogenase; n=12;... 42 0.011
UniRef50_Q1AZK2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 42 0.015
UniRef50_Q7TZG1 Cluster: 6-phosphogluconate dehydrogenase, decar... 42 0.020
UniRef50_O32911 Cluster: 6-phosphogluconate dehydrogenase, decar... 42 0.020
UniRef50_A5GJY3 Cluster: 3-hydroxyisobutyrate dehydrogenase rela... 42 0.020
UniRef50_Q9YE14 Cluster: Putative dehydrogenase; n=1; Aeropyrum ... 41 0.035
UniRef50_A5K3L2 Cluster: 6-phosphogluconate dehydrogenase, decar... 40 0.046
UniRef50_A0Y665 Cluster: 6-phosphogluconate dehydrogenase; n=3; ... 40 0.060
UniRef50_A2Q7E9 Cluster: Function: mmsB of P. aeruginosa is invo... 40 0.060
UniRef50_A4ENK2 Cluster: 3-demethylubiquinone-9 3-methyltransfer... 39 0.14
UniRef50_A1FPN2 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 38 0.18
UniRef50_Q9YFQ6 Cluster: L-lysine 6-dehydrogenase; n=1; Aeropyru... 38 0.24
UniRef50_Q2LGT9 Cluster: 6-phosphogluconate dehydrogenase; n=6; ... 38 0.24
UniRef50_Q8SRX1 Cluster: 6-PHOSPHOGLUCONATE DEHYDROGENASE; n=1; ... 38 0.32
UniRef50_A6RYG0 Cluster: Putative uncharacterized protein; n=1; ... 38 0.32
UniRef50_Q39LP6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 37 0.56
UniRef50_P41572 Cluster: 6-phosphogluconate dehydrogenase, decar... 37 0.56
UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 36 0.74
UniRef50_Q6N3Q8 Cluster: 6-phosphogluconate dehydrogenase; n=57;... 36 0.74
UniRef50_Q1YFU0 Cluster: Posibble methylase involved in ubiquino... 36 0.74
UniRef50_Q5B0A2 Cluster: Putative uncharacterized protein; n=1; ... 36 0.74
UniRef50_A6W129 Cluster: 6-phosphogluconate dehydrogenase, decar... 36 0.98
UniRef50_A4ES45 Cluster: Methyltransferase type 11; n=1; Roseoba... 36 0.98
UniRef50_A4ARS6 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 36 0.98
UniRef50_Q944B6 Cluster: Arogenate dehydrogenase 1, chloroplast ... 36 0.98
UniRef50_Q8EW86 Cluster: HAD superfamily hydrolase; n=1; Mycopla... 36 1.3
UniRef50_Q5PAV2 Cluster: 3-demethylubiquinone-9 3-methyltransfer... 35 1.7
UniRef50_Q1N6E5 Cluster: Erythronate-4-phosphate dehydrogenase; ... 35 1.7
UniRef50_Q11JE9 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 35 1.7
UniRef50_A6VZU5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 35 1.7
UniRef50_A4SGI3 Cluster: NAD-dependent epimerase/dehydratase; n=... 35 1.7
UniRef50_A1U1I8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 35 1.7
UniRef50_UPI0000E46E06 Cluster: PREDICTED: similar to MGC107852 ... 35 2.3
UniRef50_Q2S7E0 Cluster: Phosphoglycerate dehydrogenase and rela... 35 2.3
UniRef50_A4XCN7 Cluster: Methyltransferase type 11; n=2; Salinis... 35 2.3
UniRef50_A3Y0Y8 Cluster: Putative tartronate semialdehyde reduct... 35 2.3
UniRef50_A3U721 Cluster: Putative uncharacterized protein; n=1; ... 35 2.3
UniRef50_UPI0000E221EA Cluster: PREDICTED: similar to NMDAR1 sub... 34 3.0
UniRef50_UPI000050FDFD Cluster: COG0569: K+ transport systems, N... 34 3.0
UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 34 3.0
UniRef50_Q0QWD5 Cluster: Putative 3-hydroxyisobutyrate dehydroge... 34 3.0
UniRef50_Q3DWX0 Cluster: 6-phosphogluconate dehydrogenase, NAD-b... 34 4.0
UniRef50_A6G079 Cluster: Leucine dehydrogenase; n=1; Plesiocysti... 34 4.0
UniRef50_UPI0000E8153F Cluster: PREDICTED: hypothetical protein;... 33 5.2
UniRef50_Q0S6F7 Cluster: 3-demethylubiquinone-9 3-O-methyltransf... 33 5.2
UniRef50_Q0HQ96 Cluster: CHAP domain containing protein precurso... 33 5.2
UniRef50_A0Z3U5 Cluster: Putative uncharacterized protein; n=1; ... 33 5.2
UniRef50_A7QQA4 Cluster: Chromosome undetermined scaffold_141, w... 33 5.2
UniRef50_Q5KFL3 Cluster: Putative uncharacterized protein; n=2; ... 33 5.2
UniRef50_Q0VQC3 Cluster: Erythronate-4-phosphate dehydrogenase; ... 33 5.2
UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2; La... 33 6.9
UniRef50_Q6F272 Cluster: 1-pyrroline-5-carboxylate reductase; n=... 33 6.9
UniRef50_O67636 Cluster: Prephenate dehydrogenase; n=1; Aquifex ... 33 6.9
UniRef50_Q9RQV3 Cluster: Putative prephenate dehydrogenase TyrC;... 33 6.9
UniRef50_Q2BJD5 Cluster: Probable UDP-glucose/GDP-mannose dehydr... 33 6.9
UniRef50_A6TCR4 Cluster: 2-ketoacid reductase; n=1; Klebsiella p... 33 6.9
UniRef50_A6NX21 Cluster: Putative uncharacterized protein; n=1; ... 33 6.9
UniRef50_A0Q3X1 Cluster: Putative uncharacterized protein; n=1; ... 33 6.9
UniRef50_A0GGU8 Cluster: Putative uncharacterized protein; n=1; ... 33 6.9
UniRef50_Q82ZY7 Cluster: Potassium uptake protein; n=3; Bacilli|... 33 9.2
UniRef50_Q5NLA3 Cluster: Phosphoglycerate dehydrogenase; n=1; Zy... 33 9.2
UniRef50_Q1YSL7 Cluster: Putative uncharacterized protein; n=1; ... 33 9.2
UniRef50_Q0SBI0 Cluster: Probable oxidoreductase; n=1; Rhodococc... 33 9.2
UniRef50_Q0F1E8 Cluster: Putative uncharacterized protein; n=1; ... 33 9.2
UniRef50_A7IIH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 33 9.2
UniRef50_A0LNU5 Cluster: Ubiquinone biosynthesis O-methyltransfe... 33 9.2
>UniRef50_Q7NWA9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 171 bits (415), Expect = 2e-41
Identities = 90/195 (46%), Positives = 115/195 (58%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+N+AF+GLGNMGG MA NL+ KGF V +D S DAL A G A+S
Sbjct: 2 ENIAFIGLGNMGGPMAVNLLNKGFKVSAFDLSADALAKVAAAGGRAASSAADAAESASVV 61
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
S+L + K V +YLG +G+ A KG+L+ID STID +++ A EKGL DAPV
Sbjct: 62 ISMLPAGKHVAGLYLGDNGLFARLPKGALVIDCSTIDAGTARKVAEGAREKGLSMLDAPV 121
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SGG GA TL F+ GG ED + P+L+ MG FH G G+GQ AK+ NNML+GI
Sbjct: 122 SGGTAGAAAGTLTFIVGGAAEDLAHARPVLEAMGKNIFHAGGAGAGQTAKICNNMLLGIL 181
Query: 649 GMATAECMNMGH*NG 693
TAE + +G NG
Sbjct: 182 MAGTAEALALGVKNG 196
>UniRef50_Q54CX6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Dictyostelium discoideum AX4
Length = 321
Score = 167 bits (405), Expect = 3e-40
Identities = 82/199 (41%), Positives = 121/199 (60%)
Frame = +1
Query: 85 RAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXX 264
R S+++ K V F+GLGNMGG A NL+KKG + +D SKD +N + G ANS
Sbjct: 15 RYMSTSSSKTVGFIGLGNMGGHQAINLIKKGHNLIVFDMSKDNMNRLKEKGAKIANSPAE 74
Query: 265 XXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG 444
++L ++ V +VY G++G+ + G+LL+DSSTIDP +++ IA +
Sbjct: 75 VAKEADVIVTMLPASAHVKNVYCGENGIFQTVRPGTLLLDSSTIDPATAREVASIAKKHQ 134
Query: 445 LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLT 624
D PVSGG GA+ TL FM GG ++DF + L+ MG HCG +G+GQVAK+
Sbjct: 135 STMLDCPVSGGTGGAEAGTLTFMVGGSEQDFNTAKTYLECMGKNIVHCGDVGTGQVAKVC 194
Query: 625 NNMLMGITGMATAECMNMG 681
NN+++GI+ +A +E MN+G
Sbjct: 195 NNLVLGISMIAVSEAMNLG 213
>UniRef50_A7UBP6 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase; n=1; Paracoccus methylutens|Rep: Putative
3-hydroxyisobutyrate dehydrogenase - Paracoccus
methylutens
Length = 302
Score = 164 bits (399), Expect = 2e-39
Identities = 84/184 (45%), Positives = 114/184 (61%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V FLGLG MG MA NL G V YDPS++ AAK G+ A+ + +
Sbjct: 4 VGFLGLGRMGFPMARNLATAGHDVHVYDPSEEVGRKAAKAGLKTASRVDVAVEGADFVIT 63
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
++ + + VL+++LG DGV+A KGS+ IDSSTID +++ E+G+ DAPVSG
Sbjct: 64 MVPTGRHVLEIFLGDDGVLAKMAKGSMAIDSSTIDTADARRLHAAGRERGIAVLDAPVSG 123
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
GVMGA+ TL FM GG ED ER+ P+L+ MG + FH G+ G GQ AKL NN+L GI+ +
Sbjct: 124 GVMGAEAGTLTFMVGGSAEDLERARPVLEAMGRRIFHAGEPGVGQAAKLCNNLLAGISMI 183
Query: 655 ATAE 666
A +E
Sbjct: 184 AVSE 187
>UniRef50_UPI0000D56743 Cluster: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to
3-hydroxyisobutyrate dehydrogenase - Tribolium castaneum
Length = 315
Score = 164 bits (398), Expect = 2e-39
Identities = 85/189 (44%), Positives = 113/189 (59%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+AF+G+GNMG MA NLVKKG TVR +D + NA + G N+ +
Sbjct: 26 LAFIGIGNMGSRMANNLVKKGETVRVFDLTP--ANAKSVPGAQVCNNQEEAVKDASVIIT 83
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L + +V D LG +G++ HA KGSLLID STI P V +++ G F DAPVSG
Sbjct: 84 MLPNGDIVKDTVLGTNGILKHASKGSLLIDCSTIQPQVAQEVSKATYSAGFKFLDAPVSG 143
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
GV GA+ TL FM GG K+ + P+L MGA HCG G+GQ+AKL NN+++ IT +
Sbjct: 144 GVTGAEAGTLTFMVGGDKQVLNSADPILMKMGANVLHCGDSGAGQIAKLCNNLILAITMI 203
Query: 655 ATAECMNMG 681
T E MN+G
Sbjct: 204 GTCEGMNLG 212
>UniRef50_P28811 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=72;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Pseudomonas aeruginosa
Length = 298
Score = 159 bits (386), Expect = 6e-38
Identities = 87/194 (44%), Positives = 114/194 (58%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
++AFLGLGNMGG MAANL+K G V +D A+ + G A+S
Sbjct: 3 DIAFLGLGNMGGPMAANLLKAGHRVNVFDLQPKAVLGLVEQGAQGADSALQCCEGAEVVI 62
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
S+L + + V +YLG DG++A LLID STI P +++ A KGL DAPVS
Sbjct: 63 SMLPAGQHVESLYLGDDGLLARVAGKPLLIDCSTIAPETARKVAEAAAAKGLTLLDAPVS 122
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
GGV GA+ TL+F+ GG E F R+ P+L+ MG FH G G+GQVAK+ NNML+GI
Sbjct: 123 GGVGGARAGTLSFIVGGPAEGFARARPVLENMGRNIFHAGDHGAGQVAKICNNMLLGILM 182
Query: 652 MATAECMNMGH*NG 693
TAE + +G NG
Sbjct: 183 AGTAEALALGVKNG 196
>UniRef50_A7JGH8 Cluster: Predicted protein; n=1; Francisella
tularensis subsp. novicida GA99-3549|Rep: Predicted
protein - Francisella tularensis subsp. novicida
GA99-3549
Length = 293
Score = 155 bits (375), Expect = 1e-36
Identities = 86/195 (44%), Positives = 106/195 (54%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
KN+AF+GLG MG MA NL+ G+ V G+D S D LN NG A SI
Sbjct: 2 KNIAFIGLGCMGLHMAKNLIDNGYKVYGFDMSLDQLNKHQNNGGIAAKSIKEACGYADAI 61
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
L V +V DG++ AK G+++ID+STID N + A + L DAPV
Sbjct: 62 ILSLPGPNQVSNVCDSSDGILKIAKAGTIIIDTSTIDANTSVLLAKKAKQNNLHMLDAPV 121
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SGG++GAQNATL FM GG KE FER L MG K H G G G + KL NNML+GI
Sbjct: 122 SGGIIGAQNATLTFMVGGDKEIFERCKNLFNSMGKKYLHVGDNGKGLIIKLINNMLLGIN 181
Query: 649 GMATAECMNMGH*NG 693
+A +E N G
Sbjct: 182 MIAASEACNFAEKTG 196
>UniRef50_P31937 Cluster: 3-hydroxyisobutyrate dehydrogenase,
mitochondrial precursor; n=38; Eumetazoa|Rep:
3-hydroxyisobutyrate dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 336
Score = 150 bits (364), Expect = 3e-35
Identities = 82/199 (41%), Positives = 116/199 (58%)
Frame = +1
Query: 85 RAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXX 264
R+ +S T V F+GLGNMG MA NL+K G+ + YD DA G +S
Sbjct: 34 RSVASKTP--VGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQVVSSPAD 91
Query: 265 XXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG 444
++L ++ ++ Y G +G++ KKGSLLIDSSTIDP V K++ + G
Sbjct: 92 VAEKADRIITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMG 151
Query: 445 LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLT 624
F DAPVSGGV A++ L FM GG +++F + LL MG+ +CG +G+GQ AK+
Sbjct: 152 AVFMDAPVSGGVGAARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQAAKIC 211
Query: 625 NNMLMGITGMATAECMNMG 681
NNML+ I+ + TAE MN+G
Sbjct: 212 NNMLLAISMIGTAEAMNLG 230
>UniRef50_Q399N0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=72;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 299
Score = 146 bits (353), Expect = 6e-34
Identities = 81/189 (42%), Positives = 105/189 (55%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLG+MG MA NL+K G V +D S DAL A G A S +
Sbjct: 3 IGFIGLGHMGAPMALNLLKAGHEVHAFDLSADALRALQDAGAQVAASPRDAASGATFVIT 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L + V V G++GV+A G+ +IDSSTIDP + + E G F DAPVSG
Sbjct: 63 MLPAAPHVRSVLSGENGVLAGLGAGATVIDSSTIDPASAQAFGALVREHGGAFVDAPVSG 122
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G GA TL FM GG DFER P+L MG HCG G GQVAK+ NN+++GI+
Sbjct: 123 GTGGAAAGTLTFMVGGSDADFERVKPVLAGMGKNIVHCGATGMGQVAKVCNNLVLGISMA 182
Query: 655 ATAECMNMG 681
A +E M++G
Sbjct: 183 AVSEAMSLG 191
>UniRef50_A1QPH6 Cluster: 3-hydroxyisobutyrate dehydrogenase mmsB;
n=5; Mycobacterium|Rep: 3-hydroxyisobutyrate
dehydrogenase mmsB - Mycobacterium tuberculosis (strain
F11)
Length = 315
Score = 142 bits (345), Expect = 6e-33
Identities = 79/184 (42%), Positives = 107/184 (58%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+AFLGLGNMG M+ANLV G VRG+DP+ A + AA +GV S +
Sbjct: 4 IAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVIT 63
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L + +VV Y V+A A+ +L IDSSTI +++ +A G+ DAPVSG
Sbjct: 64 MLPTGEVVRRCYTD---VLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSG 120
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
GV GA ATLAFM GG + R+ P+L+ M K HCG G+GQ AK+ NNM++ + +
Sbjct: 121 GVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLAVQQI 180
Query: 655 ATAE 666
A AE
Sbjct: 181 AIAE 184
>UniRef50_P63936 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=25; Bacteria|Rep: Probable
3-hydroxyisobutyrate dehydrogenase - Mycobacterium bovis
Length = 294
Score = 142 bits (345), Expect = 6e-33
Identities = 79/184 (42%), Positives = 107/184 (58%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+AFLGLGNMG M+ANLV G VRG+DP+ A + AA +GV S +
Sbjct: 4 IAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVIT 63
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L + +VV Y V+A A+ +L IDSSTI +++ +A G+ DAPVSG
Sbjct: 64 MLPTGEVVRRCYTD---VLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSG 120
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
GV GA ATLAFM GG + R+ P+L+ M K HCG G+GQ AK+ NNM++ + +
Sbjct: 121 GVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLAVQQI 180
Query: 655 ATAE 666
A AE
Sbjct: 181 AIAE 184
>UniRef50_A0UF54 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia multivorans ATCC
17616|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
- Burkholderia multivorans ATCC 17616
Length = 289
Score = 140 bits (340), Expect = 2e-32
Identities = 71/188 (37%), Positives = 105/188 (55%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
K V +GLGNMG +A++L + GF V G+D + +++ A GV P S+
Sbjct: 2 KTVGVIGLGNMGRGIASSLKRAGFDVLGFDANAESVRQLADEGVRPCASVAEIASAVDVL 61
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
L ++ +V V LG GV +HAK+G ++ID++T DPN +++ G+GF D PV
Sbjct: 62 ILSLPTSAIVEAVVLGDGGVASHAKRGLIVIDTTTADPNSTRKVAAALDAHGIGFIDGPV 121
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SGG GA AT+ + GG E P+L + AKQ H G G+G V KL NN+L G+
Sbjct: 122 SGGPKGAATATMTMVLGGADEHIAAVQPVLSAISAKQVHVGPAGAGHVTKLLNNLLTGVH 181
Query: 649 GMATAECM 672
+ T+E +
Sbjct: 182 LLVTSEAV 189
>UniRef50_Q9V8M5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor; n=4;
Diptera|Rep: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor - Drosophila
melanogaster (Fruit fly)
Length = 324
Score = 140 bits (338), Expect = 4e-32
Identities = 80/204 (39%), Positives = 110/204 (53%), Gaps = 2/204 (0%)
Frame = +1
Query: 73 TAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPAN 252
T R + KN+ F+GLGNMG MA+NL+K G + +D SK A + A G T
Sbjct: 17 TLVRAMSTQGGAKNIGFVGLGNMGANMASNLIKAGHKLHVFDISKPACDGLAAKGATVYA 76
Query: 253 SIXXXXXXXXXXXSILTSNKVVLDVY--LGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP 426
++L +N +V Y + DGV K ++ IDSSTI P++ K +
Sbjct: 77 KTSELAKNSDFVITMLPNNAIVDASYDEMTADGV----NKDTIFIDSSTISPDLVKSLQK 132
Query: 427 IALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSG 606
KG F DAPVSGGV GA+ ATL FM GG + ++ +L+ MG K HCG G G
Sbjct: 133 KISAKGARFIDAPVSGGVPGAEQATLTFMVGGTEAEYNAVKAVLECMGKKITHCGVYGMG 192
Query: 607 QVAKLTNNMLMGITGMATAECMNM 678
Q AKL NNM++ I+ + +E MN+
Sbjct: 193 QAAKLCNNMMLAISMIGVSEAMNL 216
>UniRef50_Q4FMJ3 Cluster: 6-phosphogluconate dehydrogenase; n=2;
Candidatus Pelagibacter ubique|Rep: 6-phosphogluconate
dehydrogenase - Pelagibacter ubique
Length = 289
Score = 139 bits (336), Expect = 7e-32
Identities = 72/196 (36%), Positives = 119/196 (60%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+N++F+G+G MG MA NL+K GF +R Y+ S+D + + G + SI
Sbjct: 2 QNISFIGIGLMGFPMAKNLLKSGFNLRAYNRSQDKADRLKEFGAEISTSIKDVVTNSDVI 61
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
++LT + V V +G D +++ K+G+ +ID S+++P + K+ F I EK + + DAPV
Sbjct: 62 ITMLTDDAAVEKV-MGSDEFISNIKEGATVIDMSSVNPVITKKYFKILKEKNINYLDAPV 120
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SGG +GA+ A+LA M GG +E F++ LLK++G G + SGQ++KL N +++G+T
Sbjct: 121 SGGTIGAEEASLAIMVGGDEETFKQCYDLLKILGNPTL-VGPVTSGQISKLANQIIVGVT 179
Query: 649 GMATAECMNMGH*NGT 696
A AE + + +GT
Sbjct: 180 IGAVAEAVTLCEKSGT 195
>UniRef50_A0JUJ6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Micrococcineae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 300
Score = 138 bits (333), Expect = 2e-31
Identities = 76/184 (41%), Positives = 105/184 (57%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
VA++GLGNMGG M+ANL K G VRG+D + +A+ AA GV P SI +
Sbjct: 4 VAWIGLGNMGGSMSANLAKAGHDVRGFDLNPEAVAAAEAGGVKPVASIAAAVDGADVVFT 63
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L + VYLG+DGV+AHA + +LL+DSSTID + + A G F DAPVSG
Sbjct: 64 MLPKGEHARAVYLGEDGVLAHADRRTLLVDSSTIDIASAQALHDAAAAAGFRFVDAPVSG 123
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G+ GA+ TL FM GG + ++ M + G +GQ AK+ NN+++ I
Sbjct: 124 GMSGAKAGTLTFMIGGDAGAVAEATEYIRPMASNIIPTGGPTTGQAAKICNNLMLFINLA 183
Query: 655 ATAE 666
+TAE
Sbjct: 184 STAE 187
>UniRef50_Q0K0E2 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1;
Ralstonia eutropha H16|Rep: 3-Hydroxyisobutyrate
dehydrogenase - Ralstonia eutropha (strain ATCC 17699 /
H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain
ATCC 17699 / H16 / DSM 428 / Stanier337))
Length = 299
Score = 137 bits (332), Expect = 2e-31
Identities = 74/189 (39%), Positives = 108/189 (57%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+AF+GLGNMG MA NLV+ G V+G+D S+ AL A G S+ S
Sbjct: 4 IAFIGLGNMGMPMALNLVRAGHDVQGFDISEAALAGFAGQGGQSQRSVAAAVDGASIVIS 63
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
I+ + V ++Y GV+ A G+LLI+SSTI P + + A + G DAPV+G
Sbjct: 64 IVRNADDVKNLYCTAGGVLDVAAPGALLIESSTIGPAAARAVAAEAAQAGFAMLDAPVAG 123
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G GA+ A L FM GG + F+R+ P+L+ MGA+ F+ G G+GQ+AKL NN++ ++
Sbjct: 124 GQAGAREARLTFMVGGARTAFDRAEPVLRQMGARIFYAGASGNGQIAKLCNNLIACVSSA 183
Query: 655 ATAECMNMG 681
+E +G
Sbjct: 184 VVSEAFILG 192
>UniRef50_A0QSJ0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 290
Score = 136 bits (330), Expect = 4e-31
Identities = 78/184 (42%), Positives = 101/184 (54%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+AFLGLG+MGG MAANL G TVRG+DP + AA G+ + +
Sbjct: 4 IAFLGLGHMGGPMAANLAAAGHTVRGFDPMPASREAAEAKGIKVFGTGAEAASEAEVVIT 63
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
L + +V Y V+ A G+L ID+STI + + + ALEKG DAPVSG
Sbjct: 64 SLPNGDIVKSCYAE---VLPAAPTGTLFIDTSTISVDDARTVHTQALEKGHAQLDAPVSG 120
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
GV GA TLAFM GG + ER+ P+L M K HCG G+GQ AKL NNM++ + +
Sbjct: 121 GVKGATAGTLAFMVGGEDDAVERARPILDPMAGKIIHCGGSGTGQAAKLCNNMVLAVQQI 180
Query: 655 ATAE 666
A E
Sbjct: 181 AIGE 184
>UniRef50_Q55702 Cluster: Uncharacterized oxidoreductase slr0229;
n=4; Cyanobacteria|Rep: Uncharacterized oxidoreductase
slr0229 - Synechocystis sp. (strain PCC 6803)
Length = 290
Score = 136 bits (328), Expect = 7e-31
Identities = 79/199 (39%), Positives = 105/199 (52%), Gaps = 2/199 (1%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPS--KDALNAAAKNGVTPANSIXXXXXXXXXX 288
+A GLG MG MA NLVK G+ GY+ + + ++ AAK GV SI
Sbjct: 6 IAVFGLGVMGSPMAQNLVKNGYQTVGYNRTLERPSVQEAAKAGVKVVTSIAVAAANADII 65
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
+ + K V + LG G+ +AK +L+ID STI ++ +GL F DAPV
Sbjct: 66 LTCVGDEKDVQQLILGSGGIAEYAKPQALIIDCSTIGKTAAYELATNLKLQGLRFLDAPV 125
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
+GG +GA N TL M GG DFE +LP+LK +G K HCG GSGQ KL N +L GI
Sbjct: 126 TGGDVGAINGTLTIMVGGDISDFEEALPVLKSIGEKIVHCGPSGSGQAVKLCNQVLCGIH 185
Query: 649 GMATAECMNMGH*NGTRTE 705
+A AE + + G E
Sbjct: 186 AIAAAEAIQLSEQLGIAPE 204
>UniRef50_Q1AVA4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 309
Score = 132 bits (320), Expect = 6e-30
Identities = 75/203 (36%), Positives = 112/203 (55%), Gaps = 1/203 (0%)
Frame = +1
Query: 76 AARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPS-KDALNAAAKNGVTPAN 252
A R + + V F+GLG MG MA NL++ G+++ ++ + + A A + G A
Sbjct: 4 APRERRKAGMAEKVGFIGLGIMGRPMAENLIRAGYSLTVHNRTHQKAEEFAQQTGARTAK 63
Query: 253 SIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIA 432
S ++L + V V G+ GV+ ++GSLLID STI P V +Q+ A
Sbjct: 64 SPKEVAGQSDIIITMLPDSPDVESVVAGEGGVLEGMREGSLLIDMSTISPAVARQLAAKA 123
Query: 433 LEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQV 612
E+G DAPVSGG +GA+ TL+ M GG +EDF R+ PL +VMG H G G+GQ+
Sbjct: 124 RERGASMLDAPVSGGDVGAREGTLSIMVGGSEEDFGRARPLFEVMGKTVTHVGPSGAGQI 183
Query: 613 AKLTNNMLMGITGMATAECMNMG 681
K N +++G+T A E + +G
Sbjct: 184 VKAANQIVVGLTIEAVCEALVLG 206
>UniRef50_Q83D20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Coxiella burnetii
Length = 297
Score = 131 bits (317), Expect = 1e-29
Identities = 70/184 (38%), Positives = 105/184 (57%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLG+MG M NL+K V+ YD +A+ A K G T A S +
Sbjct: 4 IGFIGLGHMGQPMVNNLIKNNCLVKVYDVIDEAVEKAVKTGATAAASPAEVAEEADVVFT 63
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L ++ V + L G+ A + ++ IDSS+ID +++ A ++G+ DAPVSG
Sbjct: 64 MLQTSDQVRNCCLSAKGIFATINRQAIYIDSSSIDIEGSRELHKEAKKRGISMLDAPVSG 123
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
GV A+ A L FM GG KEDFER+ +L ++G K + G G+G AK+ NNML+GI+ +
Sbjct: 124 GVAAAEAAGLTFMVGGEKEDFERAKRVLGILGKKIIYAGSDGAGAAAKICNNMLLGISMI 183
Query: 655 ATAE 666
A +E
Sbjct: 184 AVSE 187
>UniRef50_Q9K9L1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Bacillus|Rep: 3-hydroxyisobutyrate dehydrogenase -
Bacillus halodurans
Length = 299
Score = 131 bits (316), Expect = 2e-29
Identities = 73/187 (39%), Positives = 96/187 (51%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+ V F+GLG MG M +LV KGF S+ + A + G S
Sbjct: 3 QKVGFVGLGTMGLPMTKHLVDKGFETYVKSRSRGPIEEAIQYGAIEVESYKELMETADIV 62
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
+ L + V+DVY G+DG++A +G +LID ST+D ++ EKG F DAPV
Sbjct: 63 MTCLPLPETVIDVYEGEDGLIAGLSQGKILIDHSTVDRETNVRVAEQIKEKGGAFLDAPV 122
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SGG MGA+ TL M GG + FERS +L G H G IGSG V KL NNM++G+
Sbjct: 123 SGGPMGAKAGTLTIMCGGEADSFERSKEVLGAYGDYIVHVGPIGSGTVVKLANNMVIGVH 182
Query: 649 GMATAEC 669
EC
Sbjct: 183 QAVLGEC 189
>UniRef50_Q8ES28 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=13;
Bacillaceae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Oceanobacillus iheyensis
Length = 299
Score = 129 bits (311), Expect = 8e-29
Identities = 69/191 (36%), Positives = 105/191 (54%), Gaps = 1/191 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLGNMG M+ L+ G+ V G+D +++ K+G A S +
Sbjct: 4 IGFIGLGNMGLPMSIGLMNSGYEVIGFDVNEERSLLFKKSGGNIALSSADLVAESDVILT 63
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
L SNK V VYL K G++ H ++ID+ST+ P + +Q+ E+ + F APVSG
Sbjct: 64 SLPSNKAVEAVYLNKGGLLDHCNSSQVVIDTSTVAPELNQQLEASLSERSIPFLAAPVSG 123
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITG 651
GV+GA+N TL M GG++E F++ +L V+G FH G QI G KL NN+L+G
Sbjct: 124 GVVGAENQTLTVMVGGKEETFQKVKDILNVIGGNVFHVGEQIDKGTTVKLINNLLIGFYT 183
Query: 652 MATAECMNMGH 684
+E + + +
Sbjct: 184 AGVSEALQIAN 194
>UniRef50_Q0SBQ9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=12;
Actinomycetales|Rep: 2-hydroxy-3-oxopropionate reductase
- Rhodococcus sp. (strain RHA1)
Length = 294
Score = 129 bits (311), Expect = 8e-29
Identities = 72/175 (41%), Positives = 94/175 (53%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+AF+GLG MG MA NL K G V GY+ D A + G T A+SI
Sbjct: 4 IAFIGLGIMGSPMACNLAKAGHQVVGYNLIPDRTAALVEAGGTAADSIAKAVAGADVVAV 63
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
++ + V V G+DGV H G+L+ID S+I P+V + A E+G DAPVSG
Sbjct: 64 MVPDSPDVQAVLTGEDGVFEHTPSGALIIDFSSIRPDVTTALAAQATERGFRLIDAPVSG 123
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 639
G GA NA L+ M GG EDFE + P+L V+G H G GSGQ K N +++
Sbjct: 124 GEAGAVNAALSIMVGGAPEDFESARPILDVVGKTVVHVGPNGSGQTVKAANQLIV 178
>UniRef50_A3I4V2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus sp. B14905|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus sp. B14905
Length = 316
Score = 129 bits (311), Expect = 8e-29
Identities = 69/193 (35%), Positives = 110/193 (56%), Gaps = 1/193 (0%)
Frame = +1
Query: 106 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 285
++ + F+GLGNMG M+ NL+K + V G+D + A+ + G S
Sbjct: 21 NRKLGFIGLGNMGLPMSINLLKANYEVYGFDTNAKAVELFTEAGGIGLASAKDVAKQCDV 80
Query: 286 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 465
+ L + ++V VYL ++G++ HAKKG+LL+D ST++P++ + A GL + AP
Sbjct: 81 VMTSLPTPQIVEMVYLSEEGIIHHAKKGALLVDFSTVNPDLNDSLHKEASTLGLRYLGAP 140
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGS-GQVAKLTNNMLMG 642
VSGGV+GA NATL M GG K+D++ + + ++G +H G S G KL NN+++G
Sbjct: 141 VSGGVIGAVNATLTIMVGGGKDDYDSASEIFGIVGKNIYHLGLSSSVGTRLKLLNNLMIG 200
Query: 643 ITGMATAECMNMG 681
A AE + +G
Sbjct: 201 FYTEAVAETIVLG 213
>UniRef50_A6NVP0 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 306
Score = 128 bits (310), Expect = 1e-28
Identities = 67/189 (35%), Positives = 97/189 (51%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLG MG MA NL+ G+ V +D + A+ G S
Sbjct: 8 IGFIGLGAMGRPMATNLLTAGYEVHAFDVVEAAVKEMEGKGAIGHPSAGEMAGHVDVIIC 67
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
L + K+V GK+GV + K+G+++ID S++ PN K + A EKG+ + DAPVSG
Sbjct: 68 SLPNAKIVEGTMCGKNGVFENCKEGTVIIDMSSVAPNTTKAMAKKAAEKGIHYIDAPVSG 127
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
GV GA TL M G E F + P+ V+G +H G+ G G K+ NN+L+G
Sbjct: 128 GVSGAAAGTLTIMVGADDETFNKVKPIFDVLGKNIYHVGEAGGGDAIKMVNNLLLGCNMA 187
Query: 655 ATAECMNMG 681
A AE + +G
Sbjct: 188 ALAEALTLG 196
>UniRef50_Q22B54 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Tetrahymena thermophila SB210
Length = 316
Score = 128 bits (310), Expect = 1e-28
Identities = 75/193 (38%), Positives = 108/193 (55%), Gaps = 2/193 (1%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKG-FTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 285
+ V F+GLGNMGG MA NL +KG F V +D +KD+L AK G+ +
Sbjct: 17 ETVGFIGLGNMGGPMALNLARKGGFEVIAFDVNKDSLKKYAKEGLAVCEDVTVLARKANK 76
Query: 286 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 465
++L ++ V V G++G+ + K SL IDSSTI + +I+ A + + DAP
Sbjct: 77 FVTMLPNSSHVSSVLEGENGLFQKSAKNSLFIDSSTISYHAAIKIYENAKKVNQRYIDAP 136
Query: 466 VSGGVMGAQNATLAFMAGG-RKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 642
VSGGV A TL FM G KE F+ LL+ MG +C + G+G +AK+ NNM +G
Sbjct: 137 VSGGVGAATAGTLTFMVGAENKELFQECKNLLQHMGKNIANCEKPGAGSIAKICNNMALG 196
Query: 643 ITGMATAECMNMG 681
I +A AE +++G
Sbjct: 197 IEMIAVAEAISLG 209
>UniRef50_Q9A8J9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=24;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 298
Score = 128 bits (308), Expect = 2e-28
Identities = 74/184 (40%), Positives = 98/184 (53%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+AF+GLGNMGG MAAN K VR +D S A+ A G A S+ +
Sbjct: 4 IAFIGLGNMGGGMAANQAKAQHQVRAFDLSAAAVERAVAAGCLAAASVAEAVAEAEIVIT 63
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L + V VY + ++ +A K +LLID STID + + + A E G F DAPVSG
Sbjct: 64 MLPAGPHVRAVYA--EQILPNAPKSALLIDCSTIDVDSARVVARQAAEAGFRFADAPVSG 121
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G+M A+ TLAFM G DF L M H G G+GQ AK+ NNML+G++ +
Sbjct: 122 GIMAAEAGTLAFMVGCEASDFAAVEAALAPMSRVTIHAGDHGAGQAAKICNNMLLGVSML 181
Query: 655 ATAE 666
T E
Sbjct: 182 GTCE 185
>UniRef50_A5V0D4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Chloroflexaceae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Roseiflexus sp. RS-1
Length = 303
Score = 127 bits (306), Expect = 3e-28
Identities = 70/188 (37%), Positives = 102/188 (54%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+ V F+GLG MG MA N++K GF +R ++ + ++ A G PA+S
Sbjct: 5 ERVGFIGLGIMGRGMARNILKAGFPLRVWNRTASRMDELAAEGAGPASSPGDLAFHSDII 64
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
+ ++ V V LG+ GV+ A+ GSL+ID STI P ++I E+ + DAPV
Sbjct: 65 ITCVSDTPDVEQVLLGEGGVIHGARPGSLVIDMSTISPRATQRIAAHLAERHIHMLDAPV 124
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SGG GA TL+ M GG FER+LP+ + MG H G IG+GQ KL N +L+
Sbjct: 125 SGGSEGAARGTLSIMVGGDVTQFERALPVFQAMGTTITHLGPIGAGQTTKLVNQILVVGH 184
Query: 649 GMATAECM 672
+A +E +
Sbjct: 185 ALAMSEAL 192
>UniRef50_Q4ZQL5 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=11; Proteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase precursor -
Pseudomonas syringae pv. syringae (strain B728a)
Length = 296
Score = 126 bits (305), Expect = 4e-28
Identities = 68/185 (36%), Positives = 99/185 (53%)
Frame = +1
Query: 124 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILT 303
+GLGNMGG MAA L KGF V G+D S+ AL A GV P L
Sbjct: 8 IGLGNMGGGMAATLAGKGFDVSGFDLSQAALAQAESKGVKPVADRTQLIQGVDILILSLP 67
Query: 304 SNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVM 483
+ V V LG G+ +KG +++D++T P + +++ + G+ F DAPVSGG
Sbjct: 68 KAEHVESVCLGAGGINEVGRKGLIVVDTTTSTPEMSRKVAAELAKNGIAFIDAPVSGGPK 127
Query: 484 GAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATA 663
GA +++ + G D R++P+L+ M + H GQ G+G VAK+ NNML ++TA
Sbjct: 128 GAATGSMSMVIGAEDADLARAMPVLEGMSGTRVHVGQCGAGNVAKIANNMLAACHLISTA 187
Query: 664 ECMNM 678
E + M
Sbjct: 188 EAVAM 192
>UniRef50_Q1V2R0 Cluster: MmsB-like protein; n=2; Candidatus
Pelagibacter ubique|Rep: MmsB-like protein - Candidatus
Pelagibacter ubique HTCC1002
Length = 308
Score = 126 bits (305), Expect = 4e-28
Identities = 69/187 (36%), Positives = 103/187 (55%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
++AF+G+GNMG MA LVK G V+ +D S + + A ++G+ ++I
Sbjct: 4 HIAFIGVGNMGNPMADQLVKAGKEVKAFDVSPEVIKIAKESGLNVVSTIDELLDGASTVI 63
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
S+L K V +YLG G++ K L+ID STID ++ + + G+ DAPV+
Sbjct: 64 SMLPEGKHVRSLYLGDKGILNKIPKECLIIDCSTIDIETSLELGNESKKLGIKMIDAPVT 123
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
GGVMGA+ L F+ GG E + PL +MG K H G GSG K+ NNM +GI+
Sbjct: 124 GGVMGARIGKLNFLVGGSDEAVALAKPLFDIMGQKILHAGVQGSGVGVKICNNMSLGISM 183
Query: 652 MATAECM 672
+A +E +
Sbjct: 184 IAASESL 190
>UniRef50_A3RRS1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=11;
Betaproteobacteria|Rep: 2-hydroxy-3-oxopropionate
reductase - Ralstonia solanacearum UW551
Length = 298
Score = 126 bits (305), Expect = 4e-28
Identities = 79/198 (39%), Positives = 101/198 (51%), Gaps = 4/198 (2%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+AF+GLGNMG M +LV G VR Y +A + A G P +S +
Sbjct: 4 IAFIGLGNMGSPMVGHLVAAGHAVRAYVRRPEAADRARALGAEPCDSPADAARDAEVVFT 63
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKG----SLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 462
+TS V V LG DGV+ A +G ++ ID STI ++I GL F DA
Sbjct: 64 NVTSTADVEAVLLGPDGVIHGAPRGKPGSAVCIDHSTISAVATRRIAAELETAGLDFLDA 123
Query: 463 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 642
PVSGG MGAQ ATL+ M GG+ E ER PLL+++G H G G+GQVAK N ++
Sbjct: 124 PVSGGTMGAQKATLSIMVGGKAEVLERVRPLLQLLGTTITHIGDHGAGQVAKACNQIVQV 183
Query: 643 ITGMATAECMNMGH*NGT 696
I AE M GT
Sbjct: 184 INIQGIAEAMLFARAQGT 201
>UniRef50_O34948 Cluster: Uncharacterized oxidoreductase ykwC; n=19;
cellular organisms|Rep: Uncharacterized oxidoreductase
ykwC - Bacillus subtilis
Length = 288
Score = 126 bits (304), Expect = 5e-28
Identities = 69/199 (34%), Positives = 106/199 (53%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
K + F+GLG MG MA++++ G V Y +K+ + + G +++
Sbjct: 3 KTIGFIGLGVMGKSMASHILNDGHPVLVYTRTKEKAESILQKGAIWKDTVKDLSKEADVI 62
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
+++ V +VY G +G++ +AK+G+ LID +T P++ K+I A EK L DAPV
Sbjct: 63 ITMVGYPSDVEEVYFGSNGIIENAKEGAYLIDMTTSKPSLAKKIAEAAKEKALFALDAPV 122
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SGG +GAQN TLA M GG KE FE +P+ +MG + G GSGQ K+ N + +
Sbjct: 123 SGGDIGAQNGTLAIMVGGEKEAFEACMPIFSLMGENIQYQGPAGSGQHTKMCNQIAIAAG 182
Query: 649 GMATAECMNMGH*NGTRTE 705
+ AE M +G E
Sbjct: 183 MIGVAEAMAYAQKSGLEPE 201
>UniRef50_A4IN46 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=2; Geobacillus|Rep: 3-hydroxyisobutyrate
dehydrogenase-like protein - Geobacillus
thermodenitrificans (strain NG80-2)
Length = 304
Score = 124 bits (299), Expect = 2e-27
Identities = 66/190 (34%), Positives = 103/190 (54%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
NV F+GLG MG MA L+ GF V Y+ + + ++G A +I
Sbjct: 3 NVGFIGLGMMGSRMAKRLLDAGFPVTVYNRTPEKAAILVESGARQAETIAALASEVDVIC 62
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
+ L+ V++VY G+ GV++ A++G + +D +T+ P + + A E+G+ + DAPVS
Sbjct: 63 TCLSMPDDVINVYTGEGGVLSAARRGVICLDFTTVGPKTSRFVAGRAGERGVAYLDAPVS 122
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
GG GA+ TL M GG + +ER PLL V+G + G+ G+G AK+ N L+ +
Sbjct: 123 GGPEGAEQGTLTIMVGGDQAAWERVRPLLSVLGKTVEYLGESGAGSAAKILNQYLVAVHS 182
Query: 652 MATAECMNMG 681
+A AE M G
Sbjct: 183 VAAAEAMVAG 192
>UniRef50_Q9SUC0 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor; n=13;
Magnoliophyta|Rep: Probable 3-hydroxyisobutyrate
dehydrogenase, mitochondrial precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 347
Score = 124 bits (299), Expect = 2e-27
Identities = 71/217 (32%), Positives = 116/217 (53%), Gaps = 12/217 (5%)
Frame = +1
Query: 67 LYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTP 246
L+ + + +SN +NV F+GLGNMG M NL++ G+ V +D ++D + + GV+
Sbjct: 24 LHRFSSSSQNSNQFQNVGFIGLGNMGFRMVNNLIRAGYKVTVHDINRDVMKMFTEMGVSS 83
Query: 247 ANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAK--KGSLLIDSSTIDPNVPKQI 420
+ ++L S+ V+DVY G +G++ + +L IDSSTIDP ++I
Sbjct: 84 RETPYEVAQDSEVVITMLPSSSHVMDVYTGTNGLLLGENDIRPALFIDSSTIDPQTTRKI 143
Query: 421 FPIALEKGLG----------FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMG 570
L DAPVSGGV+ A+ TL FM GG ++ + + P+L+ MG
Sbjct: 144 SLAVSNCNLKEKRDNWEKPVMLDAPVSGGVLAAEAGTLTFMVGGPEDAYLAARPILQSMG 203
Query: 571 AKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMG 681
+CG G+G AK+ NN+ M ++ + T+E + +G
Sbjct: 204 RTSIYCGGSGNGSAAKICNNLAMAVSMLGTSEALALG 240
>UniRef50_Q0QLF5 Cluster: 2-hydroxymethyl glutarate dehydrogenase;
n=1; Eubacterium barkeri|Rep: 2-hydroxymethyl glutarate
dehydrogenase - Eubacterium barkeri (Clostridium
barkeri)
Length = 301
Score = 124 bits (298), Expect = 3e-27
Identities = 65/197 (32%), Positives = 104/197 (52%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLG MG MA NL+K+G TV +D + + A G + +
Sbjct: 7 IGFIGLGAMGKPMAINLLKEGVTVYAFDLMEANVAAVVAQGAQACENNQKVAAASDIIFT 66
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
L + +V V G GV++ K G++++D S++ P+ ++ +A EKG+ + DAPVSG
Sbjct: 67 SLPNAGIVETVMNGPGGVLSACKAGTVIVDMSSVSPSSTLKMAKVAAEKGIDYVDAPVSG 126
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G GA+ TL M G + FE+ P+L V+G +H G G+G K+ NN+L+G
Sbjct: 127 GTKGAEAGTLTIMVGASEAVFEKIQPVLSVIGKDIYHVGDTGAGDAVKIVNNLLLGCNMA 186
Query: 655 ATAECMNMGH*NGTRTE 705
+ AE + +G G + E
Sbjct: 187 SLAEALVLGVKCGLKPE 203
>UniRef50_Q11FC5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Rhizobiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mesorhizobium sp. (strain
BNC1)
Length = 292
Score = 123 bits (297), Expect = 4e-27
Identities = 70/184 (38%), Positives = 98/184 (53%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+AF+G G MG M ANL K GF ++ YD S AL +GVT A+S+ +
Sbjct: 4 LAFIGAGVMGRPMIANLRKAGFALKAYDRSPAALENLRSDGVTVADSLAAAVAGADVVVT 63
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L V V LG+DG+ G+L+ID STI + + I +G+ DAPVSG
Sbjct: 64 MLPDTPHVQSVLLGEDGIGTLLPTGTLVIDMSTISASGIRAIGQDLASRGVDLVDAPVSG 123
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
GV GA L+ M GG E F ++ P+L+ MG H G +G GQV K+ N +++G+
Sbjct: 124 GVRGAIAGELSIMCGGSPEAFAKARPVLEGMGTTIIHAGDLGMGQVFKMCNQLMVGVHIQ 183
Query: 655 ATAE 666
A E
Sbjct: 184 AMCE 187
>UniRef50_Q41DK0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Exiguobacterium sibiricum
255-15
Length = 293
Score = 122 bits (295), Expect = 7e-27
Identities = 67/188 (35%), Positives = 105/188 (55%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
K + F+GLG MG M NL+K GF+V+GY+ +K+ ++G ++I
Sbjct: 3 KTIGFIGLGVMGQGMVRNLLKAGFSVKGYNRTKEKGLPLEQDGAVIVDTIQEAVTDVDVV 62
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
SI+ + V ++YL +DG++A A G+++ID +T P + +I A + GL DAPV
Sbjct: 63 ISIVGYPQDVEEIYLAEDGILASANPGTIVIDMTTSSPALAIRIAEQAAQTGLHALDAPV 122
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
+GG +GA+N TLA + GG + F+ PL + MG G G GQ AKL N + + +
Sbjct: 123 TGGDLGAKNGTLAILVGGEEAAFDTVKPLFEAMGKSIARFGGPGQGQSAKLANQIAIAGS 182
Query: 649 GMATAECM 672
+ TAE +
Sbjct: 183 MIGTAEML 190
>UniRef50_Q1QWU9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Chromohalobacter salexigens DSM 3043|Rep:
3-hydroxyisobutyrate dehydrogenase - Chromohalobacter
salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 310
Score = 122 bits (293), Expect = 1e-26
Identities = 71/191 (37%), Positives = 99/191 (51%)
Frame = +1
Query: 106 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 285
D N+ +GLG MGG MA L GFTV G D + A + A G++ +
Sbjct: 10 DMNIVVIGLGQMGGNMAMTLHAAGFTVTGTDVADAARDNLAARGLS-VTRLDALPEADVY 68
Query: 286 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 465
S+ TS V +V G++ A KGS+++D+ST DP V +++ +E GL + DAP
Sbjct: 69 LLSLPTSAHV-REVIETSPGLLQRAPKGSVIVDTSTSDPAVTRELAGKVVEAGLEWLDAP 127
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 645
VSGG GA + L + GG ER P+L+ M A+ H G GSG V KL NN L
Sbjct: 128 VSGGPAGAASGALGMLLGGESATIERLAPMLEAMSARHTHVGPAGSGHVVKLANNYLCAA 187
Query: 646 TGMATAECMNM 678
+ TAE + +
Sbjct: 188 HLLTTAEAVTL 198
>UniRef50_Q97XZ7 Cluster: Oxidoreductase; n=6; Thermoprotei|Rep:
Oxidoreductase - Sulfolobus solfataricus
Length = 289
Score = 122 bits (293), Expect = 1e-26
Identities = 65/184 (35%), Positives = 99/184 (53%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V F+GLG MG MA+NL+K G+ + Y+ + + K G A+S S
Sbjct: 3 VGFIGLGIMGFPMASNLLKAGYDLTVYNRTIEKAEKLGKMGAKVAHSPKEVAEVSEIVIS 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
++T V +V G++GVV K+G + +D ST P K++ E G+ F DAPV+G
Sbjct: 63 MVTDAPDVEEVLFGENGVVKSNKRGLIFVDMSTNSPEFAKKVTKRLSEYGMEFLDAPVTG 122
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G GA+ TL M GG+++ F+R P+ K MG H G +GSGQ KL N +++ + +
Sbjct: 123 GDKGAREGTLTIMVGGKEDVFKRVEPIFKAMGKNIIHVGDVGSGQALKLCNQVVVALNMV 182
Query: 655 ATAE 666
+ E
Sbjct: 183 SVVE 186
>UniRef50_Q8KL12 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Rhizobium etli CFN 42|Rep: Probable
6-phosphogluconate dehydrogenase protein - Rhizobium
etli (strain CFN 42 / ATCC 51251)
Length = 294
Score = 121 bits (292), Expect = 2e-26
Identities = 72/196 (36%), Positives = 102/196 (52%)
Frame = +1
Query: 94 SSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXX 273
S + VAF+GLG MGG MA +L+ F V G+D S +A A G PA ++
Sbjct: 2 SPRKNLRVAFIGLGAMGGPMAQHLLSAQFEVTGFDLSAEARERFAAVGGVPAETVAEAFN 61
Query: 274 XXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGF 453
++L + K+V D L KDG +L+ID S+ PN +++ +KGL
Sbjct: 62 GADVAVTMLPNGKIVQDA-LFKDGAWQSLSADALVIDMSSSAPNDTRELAERLHQKGLRL 120
Query: 454 TDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNM 633
DAPVSGGV A +L MAGG +D +++ P+L MG + F G IGSG K NN
Sbjct: 121 VDAPVSGGVKRAVEGSLTIMAGGASDDIDQADPILCAMGGQIFRTGPIGSGHAMKAINNF 180
Query: 634 LMGITGMATAECMNMG 681
+ G +A E + +G
Sbjct: 181 VSGAGVLAAIEGVLLG 196
>UniRef50_A1SIN3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxyisobutyrate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 308
Score = 121 bits (291), Expect = 2e-26
Identities = 68/193 (35%), Positives = 100/193 (51%), Gaps = 3/193 (1%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+ +AF+GLGNMG MA NL+ GF V G+D +A+ G+ A +
Sbjct: 2 ERIAFIGLGNMGNSMAKNLIAAGFDVVGFDADSRTNQRSAETGIPVAADVVDAVTGADVV 61
Query: 289 XSILTSNKVVLDVYLG---KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 459
++L + ++ V LG + GV+ + G+L+IDSS+ID + A G+ F D
Sbjct: 62 ITMLPNGDILRQVLLGAGAESGVLNYLAPGALVIDSSSIDVANCLAVHESAASAGIAFLD 121
Query: 460 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 639
APVSGGV GA TL FM GG + R+ PL + MG K G +GQ K+ N M+
Sbjct: 122 APVSGGVGGAAAGTLTFMVGGDEAHVRRAWPLFEAMGKKVVRVGGPSTGQAVKMCNQMIY 181
Query: 640 GITGMATAECMNM 678
+ +A AE ++
Sbjct: 182 ASSLVAVAEAFSL 194
>UniRef50_Q930C6 Cluster: Probable; n=8; Alphaproteobacteria|Rep:
Probable - Rhizobium meliloti (Sinorhizobium meliloti)
Length = 295
Score = 120 bits (289), Expect = 4e-26
Identities = 67/188 (35%), Positives = 96/188 (51%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
VA +G G MGG + A LV+ G + +DP D + A G A S
Sbjct: 5 VALIGAGAMGGSIGARLVETGNRLTVFDPGPDKVQALVDKGAFAAPSAAEAAAVSDYVIL 64
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
L + +V G GV A A+ G+L+ID S+IDPN KQ+ A EKGL + D+P+SG
Sbjct: 65 SLNAPAIVRQAVFGDAGVAAGAQAGTLIIDMSSIDPNATKQLAADAAEKGLRWVDSPLSG 124
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G A L MAGG +D + + +L+ + + H G +G+GQ KL N +L G+ +
Sbjct: 125 GAPKALIGELTLMAGGTAQDVKDAHAVLRHVASNYTHMGSVGAGQTTKLINQVLCGLGFL 184
Query: 655 ATAECMNM 678
A AE +
Sbjct: 185 AVAEATQL 192
>UniRef50_Q67QX0 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyisobutyrate
dehydrogenase - Symbiobacterium thermophilum
Length = 294
Score = 120 bits (289), Expect = 4e-26
Identities = 72/190 (37%), Positives = 98/190 (51%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
N+ F+GLG MG MA NL++ G TV Y+ S+ ++ G A
Sbjct: 4 NLGFIGLGRMGRHMARNLIRAGHTVTLYNRSQAVVDELVAEGGRRAAGPAEVARDARVLF 63
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
+ LT+ VV + + A+ G + +D STI K+I + EKG+ F DAPVS
Sbjct: 64 TCLTTPDVVESILRQ---ALEGAQPGDIFVDHSTIGVRDAKRIAAMCAEKGVQFIDAPVS 120
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
GG GA+ TL M GG + FE LP L+V G H G +G+G VAKL NN+L+GI
Sbjct: 121 GGPWGAEAGTLTIMCGGDRAAFEAVLPYLQVEGKAIHHLGPVGAGSVAKLCNNLLVGIHT 180
Query: 652 MATAECMNMG 681
A AE +G
Sbjct: 181 AAMAEAFVLG 190
>UniRef50_Q12CU4 Cluster: 2-hydroxy-3-oxopropionate reductase; n=17;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 120 bits (288), Expect = 5e-26
Identities = 72/188 (38%), Positives = 99/188 (52%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+ + FLG G+MG MA L + G+ ++ ++ + + A G T
Sbjct: 10 RKITFLGTGSMGLPMARRLCEAGYALQVWNRTPARAASLAALGATIHEQARAAARDADIV 69
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
S+L + VV DV + GV A K GSL +D ++I P + G+ D PV
Sbjct: 70 VSMLENGAVVQDVLFAQ-GVAAAMKPGSLFLDMASITPREARDHAARLGALGIAHLDTPV 128
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SGG +GA+ TL MAGG+ DFERSLPLLKV G + H G GSGQ+ KL N M++GIT
Sbjct: 129 SGGTVGAEQGTLVIMAGGKPADFERSLPLLKVFG-RATHVGPHGSGQLTKLANQMIVGIT 187
Query: 649 GMATAECM 672
A AE +
Sbjct: 188 IGAVAEAL 195
>UniRef50_A6P2M7 Cluster: Putative uncharacterized protein; n=2;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 321
Score = 120 bits (288), Expect = 5e-26
Identities = 65/193 (33%), Positives = 101/193 (52%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+AF+G+G MG M NL+K G+++ Y +K G A+++ S
Sbjct: 38 IAFIGVGIMGKSMVRNLMKAGYSLTIYSRTKAKCEDVIAEGAVWADTVADCVRDAEAVFS 97
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
I+ K V +VY G G++++A+ G+L++D +T P + ++I+ KGL DAPV+G
Sbjct: 98 IVGYPKDVEEVYFGDGGIISNAQPGALIVDMTTSSPALAERIWEAGKAKGLRPLDAPVTG 157
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G GA+ TL+ + GG K DF+ LPL + MG H G G+GQ AKL N + +
Sbjct: 158 GDTGAKAGTLSILVGGDKVDFDACLPLFQAMGKIIVHMGSAGAGQHAKLANQIAIAGALS 217
Query: 655 ATAECMNMGH*NG 693
E + NG
Sbjct: 218 GVCEALTYARANG 230
>UniRef50_A3SJ77 Cluster: Probable oxidoreductase; n=1; Roseovarius
nubinhibens ISM|Rep: Probable oxidoreductase -
Roseovarius nubinhibens ISM
Length = 320
Score = 119 bits (287), Expect = 6e-26
Identities = 74/199 (37%), Positives = 95/199 (47%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+ VAF+GLG MG MAA LV G VRG D L A + G PA S+
Sbjct: 12 RRVAFIGLGTMGSGMAARLVAAGHEVRGVDIDSARLAAFEEVGGLPAASVAEACDGAEII 71
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
+IL + V + LG G+ A G+L+I+ STI P I KGL DAPV
Sbjct: 72 MTILPRDTHVRQICLGAGGIADSAAPGTLVIEMSTISPEASLDIHDALTSKGLRVLDAPV 131
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
AQN L MAGGR EDF + P+ + K H G GSG K+ NN + ++
Sbjct: 132 GRTPKDAQNGALLIMAGGRAEDFADAAPVFAPLADKIVHLGPKGSGIRMKIANNYMSMVS 191
Query: 649 GMATAECMNMGH*NGTRTE 705
+ TAE + M G T+
Sbjct: 192 MVLTAETLAMARKAGIDTD 210
>UniRef50_Q58PL4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
uncultured proteobacterium DelRiverFos06H03|Rep:
3-hydroxyisobutyrate dehydrogenase - uncultured
proteobacterium DelRiverFos06H03
Length = 299
Score = 118 bits (285), Expect = 1e-25
Identities = 66/187 (35%), Positives = 99/187 (52%)
Frame = +1
Query: 121 FLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSIL 300
F+G+GNMG MAANLVK G+ V +D S+ G T S+ + L
Sbjct: 10 FIGVGNMGNPMAANLVKAGYPVTVFDVSRAKAENLIALGATWVGSLAEGAVNADVVMASL 69
Query: 301 TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGV 480
V +V LG+ GV+AH K G+ +ID+ST + +++ +A KG+ F +APV+ V
Sbjct: 70 PGPVQVREVMLGEQGVLAHVKAGATVIDTSTSAVELVQELVALAKSKGVDFLEAPVTNAV 129
Query: 481 MGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAT 660
A L+ GG K+ FE+ P+ V+G K FH G+ G+G KL N+L ++ A
Sbjct: 130 DMAALGRLSIFVGGDKDCFEKHKPIFDVIGEKIFHVGEPGNGATIKLLTNLLWFVSAAAI 189
Query: 661 AECMNMG 681
E + +G
Sbjct: 190 GEGLMLG 196
>UniRef50_A6SW62 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Janthinobacterium sp. Marseille|Rep:
3-hydroxyisobutyrate dehydrogenase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 298
Score = 117 bits (282), Expect = 2e-25
Identities = 70/192 (36%), Positives = 95/192 (49%), Gaps = 1/192 (0%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNA-AAKNGVTPANSIXXXXXXXXX 285
+N+ F+G+GNMG MA L +KGF++ YD NA A ++G A S
Sbjct: 5 RNIGFIGIGNMGAPMAGQLARKGFSLTVYDTHATTANAFAQEHGARVARSAAEVGIGADA 64
Query: 286 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 465
+L S++VV V L DG+ GS+ ID T P V + I G+G+ DAP
Sbjct: 65 VIFMLPSDQVVRQV-LFTDGLATQLAPGSIAIDMGTSAPAVTRSISAELATLGIGYLDAP 123
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 645
V GGV+ A++A+L M G ER PL MG K + CG IGS V K N +
Sbjct: 124 VMGGVVFAKDASLDIMVSGDDASIERCRPLFDAMGRKLWPCGDIGSAHVLKAMTNYINAC 183
Query: 646 TGMATAECMNMG 681
+ T E M +G
Sbjct: 184 ALINTLEAMTIG 195
>UniRef50_Q183P5 Cluster: 2-hydroxy-3-oxopropionate reductase; n=5;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Clostridium difficile (strain 630)
Length = 296
Score = 117 bits (281), Expect = 3e-25
Identities = 66/184 (35%), Positives = 100/184 (54%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLG MG MA NL+K G + YD +K A++ G A S+ +
Sbjct: 3 LGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDELISCGAKYA-SVLEMGQECDIVFT 61
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
IL + +V D+ G DG+ K+GS+++D S++ P + GL F D+PVSG
Sbjct: 62 ILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTPTESILCANKLKDMGLEFIDSPVSG 121
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G A + TLAFMAGG++E +++ P +MG+ G GSG V KLTN +++ +T
Sbjct: 122 GEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSSSILIGDNGSGSVTKLTNQVIVNLTIA 181
Query: 655 ATAE 666
A +E
Sbjct: 182 AVSE 185
>UniRef50_A6GTB5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Limnobacter sp. MED105|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein -
Limnobacter sp. MED105
Length = 299
Score = 116 bits (280), Expect = 4e-25
Identities = 68/191 (35%), Positives = 93/191 (48%)
Frame = +1
Query: 103 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXX 282
T + F+GLGNMG MA +L K G+TV + + A A + P SI
Sbjct: 7 TLNTIGFIGLGNMGAAMAGHLCKAGYTVLAWARNASTFEALADIPLVPQPSIEALCASTR 66
Query: 283 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 462
+T+ V + G+ HA+ GS+++D STID I +G+ + D
Sbjct: 67 LVALNVTNTADVQSLLFRDGGIAQHAQPGSIIVDFSTIDAAAVADIARQLKSRGVDYIDC 126
Query: 463 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 642
PVSGG GA+ ATL+ MAGG F R P+LK +G H G G+GQ K N M +
Sbjct: 127 PVSGGAAGARAATLSMMAGGDLAAFNRIEPMLKHLGKTIRHVGPSGAGQAIKAANQMALC 186
Query: 643 ITGMATAECMN 675
I + AE MN
Sbjct: 187 IQLVGIAEAMN 197
>UniRef50_A2SP40 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Methylibium petroleiphilum PM1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Methylibium petroleiphilum (strain PM1)
Length = 297
Score = 116 bits (279), Expect = 6e-25
Identities = 69/185 (37%), Positives = 98/185 (52%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
K + +GLGN+GG M L+ +G V G+D S A AAA++G S
Sbjct: 2 KEIGLIGLGNIGGGMCRRLLDRGIGVVGFDLSPAATKAAAEHGARIEVSPAAVAQQVDVV 61
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
+ L + +V DVYLGK G+VA A+ GS LI++STIDPN +++ A + G+ D +
Sbjct: 62 VTSLPNPPIVRDVYLGKQGLVAQARPGSTLIETSTIDPNTIREVAQAATKSGIRILDIAL 121
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SG A L F GG E ++ L LL+V+ K G IG+ + KL NN LM +
Sbjct: 122 SGEPPQAVLGELVFQVGGPDELIDQHLELLQVLAKKINRTGGIGTAKTVKLVNN-LMSLG 180
Query: 649 GMATA 663
+A A
Sbjct: 181 NVAVA 185
>UniRef50_A0GVR3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phytofirmans PsJN|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phytofirmans PsJN
Length = 311
Score = 115 bits (277), Expect = 1e-24
Identities = 64/189 (33%), Positives = 98/189 (51%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+G G MG M +NL+K V D ++DA + A G T A ++ +
Sbjct: 3 IGFIGAGRMGHRMISNLLKGSHAVLVLDGARDARDRVASLGATLAMNLADLVTGQDIVIT 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L + V L VY G G+ + +LL++ ST+D +++ A G DAP++G
Sbjct: 63 MLPTPDVSLSVYEGAGGLFSITPPETLLLECSTVDVKTIERLGEGARASGTQLIDAPLTG 122
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G+ GA ATL FM GG +E E + P L+ MG++ H G+ GSG KL NNM+ M
Sbjct: 123 GIEGAALATLTFMVGGSEEQLEYARPALQSMGSRIVHAGRFGSGTKLKLVNNMICATNLM 182
Query: 655 ATAECMNMG 681
+E + +G
Sbjct: 183 VASEALTLG 191
>UniRef50_P0ABQ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=25;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Escherichia coli O6
Length = 294
Score = 115 bits (277), Expect = 1e-24
Identities = 63/188 (33%), Positives = 103/188 (54%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V F+GLG MG M+ NL+K G+++ D + +A+ G A++ +
Sbjct: 3 VGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAAGAETASTAKAIAEQCDVIIT 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L ++ V +V LG++G++ AK G++LID S+I P ++I KG+ DAPVSG
Sbjct: 63 MLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAPVSG 122
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G A + TL+ M GG K F++ L+K M H G+IG+G V KL N +++ +
Sbjct: 123 GEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTGEIGAGNVTKLANQVIVALNIA 182
Query: 655 ATAECMNM 678
A +E + +
Sbjct: 183 AMSEALTL 190
>UniRef50_Q1QWQ5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Chromohalobacter salexigens
(strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 315
Score = 114 bits (274), Expect = 2e-24
Identities = 70/207 (33%), Positives = 101/207 (48%)
Frame = +1
Query: 73 TAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPAN 252
T AR + +G G MG MA L + G+ VR ++ S D A +G+ A+
Sbjct: 13 TTAREDRDMQDTTTIGVIGTGLMGAPMARRLAEAGYAVRAWNRSNDKARALTAHGIDIAD 72
Query: 253 SIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIA 432
S +L+S V D+ LG +GV+AH + L+ S+I + ++ A
Sbjct: 73 S-PRDAAGADIVVVMLSSGPVCDDILLGPEGVIAHMAPHATLVVMSSIPVDTAQRQAQAA 131
Query: 433 LEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQV 612
+G+G+ DAPVSGG GA + TLA M GG FER PL +G + H G GSGQ+
Sbjct: 132 EARGIGYLDAPVSGGERGAIDGTLAIMVGGDPATFERHRPLFAPLG-RAVHVGPAGSGQL 190
Query: 613 AKLTNNMLMGITGMATAECMNMGH*NG 693
AKL N ++ T AE + + G
Sbjct: 191 AKLANQSIVANTIATVAEALLLAERGG 217
>UniRef50_A6LT11 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Clostridiales|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Clostridium beijerinckii
NCIMB 8052
Length = 291
Score = 113 bits (271), Expect = 5e-24
Identities = 63/187 (33%), Positives = 102/187 (54%), Gaps = 2/187 (1%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
K + F+G+G MG M NL+KKG+ V Y +K+ + G + +
Sbjct: 2 KTIGFIGVGVMGKSMVRNLMKKGYEVSIYTRTKEKVLDVINEGAKWCDDVKSCANNRDVI 61
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
+I+ K V +VY G++G++ +AKK S +ID +T P + +I+ A ++ + DAPV
Sbjct: 62 ITIVGYPKDVEEVYFGENGILENAKKESCIIDMTTTSPKLSIKIYNEAKKREIYALDAPV 121
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM--G 642
SGG +GA+NATL+ M GG E FE+ +L +G + G+ G+GQ K+ N + +
Sbjct: 122 SGGDVGAKNATLSIMVGGDLEVFEKHKDVLSALGTNIIYEGKAGNGQHTKMANQIALAGA 181
Query: 643 ITGMATA 663
I G+ A
Sbjct: 182 IAGVCEA 188
>UniRef50_A0C2T7 Cluster: Chromosome undetermined scaffold_145,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_145,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 299
Score = 113 bits (271), Expect = 5e-24
Identities = 67/189 (35%), Positives = 100/189 (52%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLGNMG MA NL K V YD S + + + P N + +
Sbjct: 14 IGFIGLGNMGIGMAHNLAKTR-VVYAYDVSPAWQSNIESSNIKPVNQVADVAANADTIIT 72
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L ++K+V V + +KK +LIDSSTI P ++ +A + + DAPVSG
Sbjct: 73 MLPNDKIVKSV---AQEIFKKSKK--ILIDSSTISPYTSYELAKMAQDTQNIYADAPVSG 127
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
V A+ T+ FM G KE +E+ P+LK MG F+CG+IG GQ+AK+ NM + I +
Sbjct: 128 SVSEAKLGTITFMVGAEKELYEKISPILKEMGKNIFNCGKIGEGQIAKMCGNMALAIQMI 187
Query: 655 ATAECMNMG 681
+ E + +G
Sbjct: 188 SVCEALALG 196
>UniRef50_Q92D17 Cluster: Lin1004 protein; n=10; Bacilli|Rep:
Lin1004 protein - Listeria innocua
Length = 286
Score = 111 bits (268), Expect = 1e-23
Identities = 61/188 (32%), Positives = 98/188 (52%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+ + F+G G MG MA +L++ G+ V Y +K+ A G +
Sbjct: 2 EKIGFVGTGVMGSSMAKHLLEAGYEVHIYTRTKEKAEALLSQGALWESDPGSLGAKVDIL 61
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
S++ K V +YLG++G + + K GS+ ID +T P + K+I EKG+G DAPV
Sbjct: 62 ISMVGYPKDVEQLYLGENGFLDNLKAGSVAIDMTTSSPALAKKIAEAGHEKGIGVLDAPV 121
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SGG +GA+N TLA M GG ++ F + P+ +++G+ G GSGQ K+ N + +
Sbjct: 122 SGGDIGAKNGTLAIMVGGAEDVFLKVKPIFEILGSSVILQGDAGSGQHTKMVNQIAIASN 181
Query: 649 GMATAECM 672
+ E +
Sbjct: 182 MIGVTEAI 189
>UniRef50_Q7WCG3 Cluster: Putative uncharacterized protein; n=2;
Bordetella|Rep: Putative uncharacterized protein -
Bordetella parapertussis
Length = 296
Score = 111 bits (268), Expect = 1e-23
Identities = 68/201 (33%), Positives = 99/201 (49%), Gaps = 2/201 (0%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
K VAF+G+GNMG MA + GF + D + D L A A+ GV SI
Sbjct: 5 KTVAFIGVGNMGAPMARCARRAGFELIVCDRNPDVLAAFAQEGVRVTASISDCAAADAVV 64
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGS--LLIDSSTIDPNVPKQIFPIALEKGLGFTDA 462
+L ++ +++ LG G+ G ++ ST P+ + + G DA
Sbjct: 65 V-LLANDAQIMETMLGGQGLAQAVPAGHRPIVCMMSTTLPDTLRALEAPLAAVGARLVDA 123
Query: 463 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 642
PVSGG++GA+ TL M GG D E PL++ MG + FHCG +GS ++AK+ NNML
Sbjct: 124 PVSGGIVGAEAGTLTIMMGGETADVEAVRPLMQAMGERLFHCGALGSAEIAKVINNMLCV 183
Query: 643 ITGMATAECMNMGH*NGTRTE 705
TAE + + +G E
Sbjct: 184 ANMFLTAEAIELAESHGVAFE 204
>UniRef50_Q03UI4 Cluster: 3-hydroxyisobutyrate dehydrogenase related
enzyme; n=2; Lactobacillales|Rep: 3-hydroxyisobutyrate
dehydrogenase related enzyme - Leuconostoc mesenteroides
subsp. mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 287
Score = 111 bits (266), Expect = 2e-23
Identities = 60/187 (32%), Positives = 99/187 (52%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
N+ F+G G MG + NL++ G+ V ++ + N NG ++
Sbjct: 2 NIGFIGTGVMGTGIINNLLQAGYEVSVFNRTHSKANTVLNNGAIWRDTPAKVAQYSDITF 61
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
+++ K V +V+ +DGV A AK+GS+L+D +T P + +Q+ + G DAPVS
Sbjct: 62 TMVGYPKDVEEVWTSEDGVFAGAKEGSILVDMTTSTPRLAEQLAQTGADLGFKVLDAPVS 121
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
GG +GA+N TLA M GG ++ + P+L V+G + G G GQ K++NN+ + T
Sbjct: 122 GGDIGAKNGTLAIMVGGEQQVLDEIKPVLSVIGQQIVFAGSAGKGQHMKMSNNIGVAATV 181
Query: 652 MATAECM 672
+ AE +
Sbjct: 182 ITMAESL 188
>UniRef50_A0N0V2 Cluster: BtdhL; n=1; Azoarcus anaerobius|Rep: BtdhL
- Azoarcus anaerobius
Length = 303
Score = 110 bits (265), Expect = 3e-23
Identities = 62/196 (31%), Positives = 96/196 (48%)
Frame = +1
Query: 106 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 285
D V ++GLG MG MAANL+ G + Y+ S +A + G A S+
Sbjct: 6 DTRVGWIGLGKMGTPMAANLLAAGHAITVYNRSAARADALVEKGAALAPSVAALARDCAI 65
Query: 286 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 465
S+++ + + + L GV A G + ID ST+ P + ++I A KG+ + AP
Sbjct: 66 VISMVSDDAALQGITLDAGGVFEAATPGMVFIDMSTVSPALSERIAAAASAKGIHYLRAP 125
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 645
VSG A L +A G K+ +ER LPLL+ MG K ++ G + K+ NM++G+
Sbjct: 126 VSGSTTTAAAGALTILASGPKDAYERCLPLLQAMGKKLYYLGPAEQARYLKVAINMMLGV 185
Query: 646 TGMATAECMNMGH*NG 693
T E + +G G
Sbjct: 186 TAGMLGEALALGERGG 201
>UniRef50_Q1GJB9 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=1; Silicibacter sp. TM1040|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 304
Score = 110 bits (264), Expect = 4e-23
Identities = 69/194 (35%), Positives = 99/194 (51%), Gaps = 2/194 (1%)
Frame = +1
Query: 106 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV-TPANSIXXXXXXXX 282
+K +GLG MG MA +L+K GF V GYDP++ A AA GV A++
Sbjct: 6 NKRAGVIGLGAMGLGMARSLLKAGFAVSGYDPAETARENAAAAGVWLTADTDAVFADCDV 65
Query: 283 XXXSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 459
S+ T+ V+ V + G +A +++D+ST + + + G GF D
Sbjct: 66 IVLSLPTAQHVLAVVQAAQAAGHLAQTGAARVIVDTSTSEAATSRTLAAELSALGHGFLD 125
Query: 460 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 639
APVSGG GA + L+ M GG + E + P L+ M AK H G G+G VAKL NNML+
Sbjct: 126 APVSGGPAGAASGQLSVMLGGETQWLEAARPALEAMAAKILHVGPSGAGNVAKLVNNMLV 185
Query: 640 GITGMATAECMNMG 681
+ T E + +G
Sbjct: 186 ANHMVTTLEALRLG 199
>UniRef50_Q0S5S3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 299
Score = 109 bits (263), Expect = 5e-23
Identities = 66/184 (35%), Positives = 93/184 (50%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V F+GLGN+GG + A+LVK G V YD + A++AA G S
Sbjct: 5 VGFVGLGNIGGRVVAHLVKAGHDVAVYDLNTAAVDAAVALGARSVASPGEAARKAEALFL 64
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
L + +V V V+ +G +++D STIDP+ +++ A G F DAPVSG
Sbjct: 65 SLPTPAIVEGVVAD---VLQQGNQGLVIVDHSTIDPDTTRRLAQDAQVAGACFLDAPVSG 121
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
GV GA+ TLA M GG + ++ +PL++ FH G GSGQ KL NN + +
Sbjct: 122 GVQGAEAGTLAVMLGGDEASVKKVIPLIETYAGNIFHVGPSGSGQAIKLANNQITAANIV 181
Query: 655 ATAE 666
A E
Sbjct: 182 ALGE 185
>UniRef50_Q01ZG6 Cluster: 2-hydroxy-3-oxopropionate reductase; n=6;
Bacteria|Rep: 2-hydroxy-3-oxopropionate reductase -
Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 109 bits (263), Expect = 5e-23
Identities = 64/187 (34%), Positives = 95/187 (50%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
++ F+GLG MG M+ NL+K G+++ YD + + G S
Sbjct: 3 DIGFIGLGIMGKPMSRNLMKAGYSLVVYDIFPGPVAELKEAGAGAGASCAATAAAAPIVI 62
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
++L V LG GV+ AK G++++D S+I P V +++ KG+ F DAPVS
Sbjct: 63 TMLPDGPEVETAVLGPGGVLEGAKAGTVVVDMSSISPMVSQKVAAACAAKGVEFLDAPVS 122
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
GG A + TLA M GG+ E FER P+L MGA G +G+G V KL N +++
Sbjct: 123 GGEPKAIDGTLAIMVGGKPEVFERVQPVLAKMGASVTLTGAVGAGNVTKLANQIMVACNI 182
Query: 652 MATAECM 672
A E +
Sbjct: 183 AAMGEAL 189
>UniRef50_Q5WBB8 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bacillus clausii KSM-K16|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bacillus clausii (strain KSM-K16)
Length = 283
Score = 109 bits (262), Expect = 7e-23
Identities = 65/181 (35%), Positives = 85/181 (46%), Gaps = 1/181 (0%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
K V +G G MG MA +L+ G+TV YD K G +
Sbjct: 2 KTVGLIGCGAMGKGMATSLLSAGYTVYIYDDMSKWREPLEKQGACFVENSAAVAKKAKYV 61
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
L S +V D GK+GV+ H + G L+D ST D + A KG+ + D PV
Sbjct: 62 LLSLPSPNIVADTVAGKEGVLCHLQTGGFLLDLSTTDVQTTLAMEKAAAAKGIYYLDCPV 121
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM-GI 645
SGG GA TL M GG K+ + PLL ++G + G G+GQ KL NNML+ GI
Sbjct: 122 SGGPAGADAGTLTIMVGGDKQAYFSVKPLLDILGDTILYVGDSGAGQTVKLCNNMLVAGI 181
Query: 646 T 648
T
Sbjct: 182 T 182
>UniRef50_Q2JEV5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Frankia sp. (strain CcI3)
Length = 302
Score = 108 bits (260), Expect = 1e-22
Identities = 66/198 (33%), Positives = 100/198 (50%), Gaps = 1/198 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYD-PSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
VAF+GLG MG MA +LV+ GF+ ++ + A A ++ A S
Sbjct: 3 VAFVGLGTMGFPMAGHLVRAGFSTTAFNRTAATAARWAEEHSGRIAPSPAAAATEVDVVC 62
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
+ ++ V +V LG DGV+ + G++++D +T + ++I E G+GF DAPVS
Sbjct: 63 LCVGADDDVREVVLGADGVLGALRPGAIIVDHTTTSAELAEEIAARTAEVGVGFVDAPVS 122
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
GG GA L+ M GG E ER+ P+L GA G +GSGQ+ K+ N +L+
Sbjct: 123 GGEAGAMAGRLSIMCGGDPETIERARPVLAAYGATITRIGPVGSGQLTKMVNQILVAGAV 182
Query: 652 MATAECMNMGH*NGTRTE 705
AE +N G T+
Sbjct: 183 EGAAEAINFAIAAGLDTD 200
>UniRef50_Q4KH51 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=16; Gammaproteobacteria|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 298
Score = 107 bits (258), Expect = 2e-22
Identities = 65/199 (32%), Positives = 102/199 (51%), Gaps = 5/199 (2%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGF--TVRGYDPSKDA--LNAAAKNGVTPANSIXXXXXXX 279
++ F G+G MG M L+ G+ TV +P K A + A A+ TPA
Sbjct: 7 SLGFAGIGLMGLPMCRRLLAAGYPLTVWNRNPEKCAPLVAAGARQVATPAQ----LCADA 62
Query: 280 XXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFT 456
L + +VV +V G G+ A+ G LL+D S+++P +++ +A +G+ +
Sbjct: 63 DLMLMCLANTEVVREVVFGPQGIAQGARAGQLLLDLSSLEPTATREMAAELAASRGVAWV 122
Query: 457 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 636
DAPVSGG GA+ +LA M GG D ER P+L +G + H G +G+GQV K N M+
Sbjct: 123 DAPVSGGTPGAEAGSLAIMVGGEATDVERVRPVLLTLGQRVTHMGAVGAGQVTKACNQMI 182
Query: 637 MGITGMATAECMNMGH*NG 693
+ + AE + + +G
Sbjct: 183 VACNALVIAEVVALAERSG 201
>UniRef50_A0K0Z6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=2; Micrococcineae|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 301
Score = 107 bits (258), Expect = 2e-22
Identities = 71/196 (36%), Positives = 99/196 (50%), Gaps = 3/196 (1%)
Frame = +1
Query: 100 NTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXX 279
NT +A +GLG MGG MAA L K G+ V G+DPS+ A AAA+ G+ S+
Sbjct: 2 NTSTRIAVIGLGAMGGAMAATLHKAGWDVTGFDPSEAARTAAAQTGIATTASLDDVAGTP 61
Query: 280 XXXXSILTSNKVVLDV--YLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGF 453
S+ ++ V V L G VA +ID++T +P KQ+ +A +G F
Sbjct: 62 YAVLSLPAASIVETTVPRLLAVPGTVA-------IIDTTTSEPATSKQMAHLADTQGAAF 114
Query: 454 TDAPVSGGVMGAQNATLAFMAGGRKEDFERSLP-LLKVMGAKQFHCGQIGSGQVAKLTNN 630
DAPVSGG GA + +L+ GG + P LL + G K H G GSG V KL NN
Sbjct: 115 VDAPVSGGRDGAASGSLSAFVGGTDAALAAAEPVLLALTGGKYSHIGGPGSGNVVKLLNN 174
Query: 631 MLMGITGMATAECMNM 678
+L ++ E + +
Sbjct: 175 VLAAANLVSVGEALGV 190
>UniRef50_Q0LNZ7 Cluster: 3-hydroxyisobutyrate dehydrogenase
precursor; n=1; Herpetosiphon aurantiacus ATCC
23779|Rep: 3-hydroxyisobutyrate dehydrogenase precursor
- Herpetosiphon aurantiacus ATCC 23779
Length = 301
Score = 107 bits (257), Expect = 3e-22
Identities = 66/198 (33%), Positives = 91/198 (45%), Gaps = 1/198 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVR-GYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
+ +GLG MG MA+NL++ G+ + G ++A A G A S
Sbjct: 6 IGLIGLGAMGAPMASNLLQAGYQLTVGVHQRREAAEQLALQGAIIAESYQALGENSDIVI 65
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
+++ V LG +G GS+ ID STI P + I E+ + DAPVS
Sbjct: 66 TMVPDAPQVEAALLGTNGAAYGMAAGSICIDMSTIAPTASRAIAAKLAERQIAMLDAPVS 125
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
GG A+ LA M GG FER +L+V+G + G GSG V KL NN+ + I
Sbjct: 126 GGPARAKTGELAIMVGGEPSTFERCQAVLEVLGGAVSYIGASGSGSVVKLCNNLAISIIA 185
Query: 652 MATAECMNMGH*NGTRTE 705
MA E + G NG E
Sbjct: 186 MANIEALAFGVANGVEAE 203
>UniRef50_Q7WG50 Cluster: Probable oxidoreductase; n=1; Bordetella
bronchiseptica|Rep: Probable oxidoreductase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 316
Score = 107 bits (256), Expect = 4e-22
Identities = 70/198 (35%), Positives = 95/198 (47%), Gaps = 1/198 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+AFLGLG MG MA NLVK G V GYD + AL+A A+ G A S +
Sbjct: 6 IAFLGLGAMGLPMACNLVKGGHAVTGYDLNPQALDALAQAGGQRAASAREAAAGAALVIA 65
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L + + G DG + G+L I+ STI P I E+G+ D+PV
Sbjct: 66 MLPTATHIQAALEGADGALQGMDPGALFINMSTILPQETDLIAQRLAERGMRMLDSPVGR 125
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT-G 651
M AQ TL +A G +D R+ L MG + CG++G G K+ NN MGI+
Sbjct: 126 SAMEAQRGTLLILASGSAQDKARARDALLCMGNQVIDCGEVGGGSRVKVVNN-FMGISLN 184
Query: 652 MATAECMNMGH*NGTRTE 705
TAE + + +G E
Sbjct: 185 ALTAEALTLAEASGLSVE 202
>UniRef50_Q5L168 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=15;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Geobacillus kaustophilus
Length = 288
Score = 107 bits (256), Expect = 4e-22
Identities = 56/188 (29%), Positives = 96/188 (51%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
K + F+GLG MG MA +L+K G+ + Y +K+ + G ++
Sbjct: 2 KTIGFIGLGVMGKSMARHLLKAGYPLLAYTRTKEKAEDLLQEGAVWKETVADLAREADVV 61
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
+++ + V VY G+ G++ +A+ G+ +ID +T P + + I+ A +KG+ DAPV
Sbjct: 62 MTMVGDPRDVEQVYFGEGGILENARPGTYVIDMTTSTPTLAQSIYEAAKQKGIHALDAPV 121
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SGG +GA+ TL M GG ++ F P+L+ +G G G+GQ K+ N + +
Sbjct: 122 SGGDIGAREGTLTIMVGGDEDVFLACKPILERLGTNIVRQGGAGAGQHTKMCNQIAIATN 181
Query: 649 GMATAECM 672
+ E M
Sbjct: 182 MIGVCEAM 189
>UniRef50_Q0F1Y7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Mariprofundus ferrooxydans
PV-1|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Mariprofundus ferrooxydans PV-1
Length = 289
Score = 107 bits (256), Expect = 4e-22
Identities = 63/199 (31%), Positives = 99/199 (49%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+N+ F+GLG MG MAAN++K+G + Y+ + + A G A+
Sbjct: 3 QNIGFIGLGIMGEAMAANILKQGHPLIVYNRTVEKAAALVDAGAMVADKPSLVADASDVI 62
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
+LT + V V G++G+++ +G +I+ ST+ K+ + G+ DAPV
Sbjct: 63 ILMLTGEEAVDAVLFGEEGLLSGDCEGKTVINMSTVPVECSKRWAKELADHGMTLIDAPV 122
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SG + AQ TL +AGG + PLL MG K +CG GSG KL N+L+GI
Sbjct: 123 SGSKVPAQTGTLVILAGGPEAAVRAQEPLLLSMGKKVIYCGPTGSGSAMKLAINLLLGIM 182
Query: 649 GMATAECMNMGH*NGTRTE 705
AE +++ +G +E
Sbjct: 183 TEGIAEALHLAESSGLASE 201
>UniRef50_Q89UN2 Cluster: Bll1384 protein; n=9; Bacteria|Rep:
Bll1384 protein - Bradyrhizobium japonicum
Length = 356
Score = 106 bits (255), Expect = 5e-22
Identities = 65/204 (31%), Positives = 101/204 (49%)
Frame = +1
Query: 70 YTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA 249
++ +R ++ ++ F+GLGNMG MA L++ G + +D K+ ++ G TPA
Sbjct: 42 FSRQQRIINTRNTMDIGFIGLGNMGFPMARRLIEAGNRLVVFDTRKEVVDKLVARGATPA 101
Query: 250 NSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPI 429
S + L S + L+V G +GV+ + ID ST+ + +I +
Sbjct: 102 TSPKDVADQVETVMASLPSLQASLEVATGTNGVI-EGSRVKRFIDLSTVGSTMASKIHGL 160
Query: 430 ALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQ 609
++ + D PVSGGV GA+ TLA M G K +FE P L V+G F + G+ Q
Sbjct: 161 LAKRDIVQIDCPVSGGVGGAEKGTLAVMVSGPKAEFELLKPALDVIGKVFFIGEKPGAAQ 220
Query: 610 VAKLTNNMLMGITGMATAECMNMG 681
KL NN L +AT+E + MG
Sbjct: 221 TMKLANNFLSATAIVATSEAVVMG 244
>UniRef50_A2U9T6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Bacillaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Bacillus coagulans 36D1
Length = 294
Score = 106 bits (255), Expect = 5e-22
Identities = 61/189 (32%), Positives = 96/189 (50%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ ++GLG+MG MA L+ F + Y+ + A+ G + +
Sbjct: 8 IGWIGLGHMGSPMARRLLDAHFDLFVYNRTIKKTEKLAEAGAAVCKTPKDIAENADVIVT 67
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+LT+ V +V G+DGV+A KG ++D ST+ P+ + EK F DAPVSG
Sbjct: 68 MLTNAAAVENVLQGEDGVLAGLTKGKTVVDMSTVSPSDSIRFAKWVEEKRGHFIDAPVSG 127
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
V A+ L +AGGRKE+ + P+ +V+G H G+ G G AKL+ N+L+G+T
Sbjct: 128 SVQPAKEGNLVILAGGRKEEIDAVRPMFEVLGKTIIHFGENGKGSAAKLSINLLLGLTIE 187
Query: 655 ATAECMNMG 681
+E + G
Sbjct: 188 GASEAILFG 196
>UniRef50_Q1YHQ4 Cluster: Putative 2-hydroxy-3-oxopropionate
reductase; n=1; Aurantimonas sp. SI85-9A1|Rep: Putative
2-hydroxy-3-oxopropionate reductase - Aurantimonas sp.
SI85-9A1
Length = 292
Score = 106 bits (254), Expect = 6e-22
Identities = 66/189 (34%), Positives = 94/189 (49%), Gaps = 1/189 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLG MG L + + V G+D + ++AAA GV PA S+
Sbjct: 4 IGFIGLGLMGSGFTKRLRELDYRVIGHDREAEKVSAAAAWGVEPAGSLAALCAEADIIAL 63
Query: 295 ILTSNKVVLDVYLGKDGVVAHAK-KGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
LT++ V V G DG+VA K G ++D ST + V Q+ G F DAPVS
Sbjct: 64 CLTTSDAVASVVTGADGLVASRKLSGRTVVDFSTTEMAVTHQVAAAIEAVGGRFVDAPVS 123
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
GG A+ TLA M GG ++ E + P+L+ +G + H G IG+GQ KL N +L
Sbjct: 124 GGPGAAETGTLAIMFGGSEQAAEAARPMLEQLG-RATHMGAIGTGQATKLVNQVLCLTNY 182
Query: 652 MATAECMNM 678
AE + +
Sbjct: 183 CVAAEALRL 191
>UniRef50_A1UP64 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium sp. (strain
KMS)
Length = 305
Score = 105 bits (252), Expect = 1e-21
Identities = 63/176 (35%), Positives = 87/176 (49%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
NV F+GLG MG MA +LV G V ++ S+ ++ G A S
Sbjct: 2 NVGFIGLGVMGKPMAGHLVDAGHHVVVFNRSRAKVDELEARGAVGATSPAHAGEKADVVI 61
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
++L + V +V G GV + GSL+ID STI P+ I EK + F DAPVS
Sbjct: 62 TMLPDSPEVEEVLFGPAGVTTTLRPGSLVIDCSTISPDAAVAIGARLAEKDIAFVDAPVS 121
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 639
GG GA LA M GG ++ R+ +L + A H G +G+GQ+ K N ML+
Sbjct: 122 GGEAGAIAGALAVMMGGDEDAVRRAATVLDAVAATSVHVGPVGAGQLVKAANQMLV 177
>UniRef50_A0LMG6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=9;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 309
Score = 105 bits (252), Expect = 1e-21
Identities = 58/188 (30%), Positives = 104/188 (55%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ ++G G MG M ++++KG+ ++ ++ ++G A+S +
Sbjct: 16 IGWIGTGVMGLSMCGHVMRKGYATSVHNRTRHKAAPLVESGAGWADSPRQVAEQSDVVFT 75
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L + V +VY G++G++ A+ G +L+D +T +P++ ++I A E+G DAPVSG
Sbjct: 76 MLGFPQDVREVYFGRNGLLQAARPGIILVDMTTTEPSLAREIHQAAGEQGAFAVDAPVSG 135
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G +GA+NA L+ M GG +E + P+L+ MG + G GSGQ AK+ N ++ ITG
Sbjct: 136 GDVGARNAALSIMLGGDREVVDAIRPILEAMGKNLVYLGPAGSGQHAKVCNQIV--ITGT 193
Query: 655 ATAECMNM 678
C ++
Sbjct: 194 MIGVCESL 201
>UniRef50_Q4Q7T9 Cluster: 2-hydroxy-3-oxopropionate reductase,
putative; n=6; Trypanosomatidae|Rep:
2-hydroxy-3-oxopropionate reductase, putative -
Leishmania major
Length = 299
Score = 105 bits (251), Expect = 1e-21
Identities = 62/187 (33%), Positives = 97/187 (51%), Gaps = 1/187 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V ++GLG MG MA N++K GF V ++ + + G T + +
Sbjct: 3 VGYIGLGLMGKPMAVNILKAGFPVSVWNRTASKCDDLVAAGATACATPAELAAASDVVFT 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFTDAPVS 471
L+ + V++V G +GV A +G++ +D+STI P+V ++I + EK + DAPVS
Sbjct: 63 NLSDSPDVMEVVFGPNGVAAGICEGAIFVDNSTIKPSVAQEIARRLWKEKKVRALDAPVS 122
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
GG +GA+N TL M GG LP+L +G K H G G+GQV K N +++
Sbjct: 123 GGDIGARNGTLTVMVGGDAAALATVLPVLLAVGKKVTHIGDCGAGQVCKAANQIMVAAQM 182
Query: 652 MATAECM 672
+A E +
Sbjct: 183 VALGEIL 189
>UniRef50_UPI00015B4162 Cluster: PREDICTED: similar to MGC108315
protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to MGC108315 protein - Nasonia vitripennis
Length = 276
Score = 104 bits (250), Expect = 2e-21
Identities = 52/122 (42%), Positives = 73/122 (59%)
Frame = +1
Query: 67 LYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTP 246
+YT R NV F+GLGNMGGFMA NL+KKG+ + +D +K A++ G
Sbjct: 13 IYTVGR--VGQRDFSNVGFVGLGNMGGFMAKNLLKKGYKLTVFDINKTAIDNVVSAGAKG 70
Query: 247 ANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP 426
A S+ ++L N+ VLD Y GKDG+++ AKKG+ L+DSSTIDP+V + +F
Sbjct: 71 AESVAEVSQNSEVIVTMLPMNQHVLDTYTGKDGIISSAKKGTFLVDSSTIDPSVSQTVFK 130
Query: 427 IA 432
A
Sbjct: 131 AA 132
Score = 43.6 bits (98), Expect = 0.005
Identities = 17/36 (47%), Positives = 25/36 (69%)
Frame = +1
Query: 574 KQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMG 681
K HCG G GQVAK+ NNML+ I+ + +E +++G
Sbjct: 134 KAVHCGDTGMGQVAKICNNMLLAISMIGVSEALSLG 169
>UniRef50_Q8UBW3 Cluster: Oxidoredutase; n=1; Agrobacterium
tumefaciens str. C58|Rep: Oxidoredutase - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 300
Score = 104 bits (250), Expect = 2e-21
Identities = 70/200 (35%), Positives = 102/200 (51%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
++VAF+G G MGG MA L+ GF+V+ ++ S D A +G A S
Sbjct: 10 RSVAFIGTGLMGGPMARRLLGTGFSVKVWNRSVDKAQALVADGAVLAASPAEAARGADIV 69
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
++L+ V +V L + GV KG+++IDSS+I P + ++ G+ DAPV
Sbjct: 70 ITMLSDGNAVGEV-LFEAGVAEALAKGAVVIDSSSIAPPIAREHSSRLQAMGIHHVDAPV 128
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SGGV GA TLA MAGG + + + MG + + G G+GQ+ KL N ++ IT
Sbjct: 129 SGGVPGATAGTLAIMAGGDEALISGLVDVFAPMG-RLTYVGPSGAGQLCKLANQQIVAIT 187
Query: 649 GMATAECMNMGH*NGTRTEG 708
A AE M + G EG
Sbjct: 188 IGAVAEAMMLVEAGGASREG 207
>UniRef50_A5USN9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Roseiflexus|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Roseiflexus sp. RS-1
Length = 302
Score = 104 bits (250), Expect = 2e-21
Identities = 64/199 (32%), Positives = 94/199 (47%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+ + F+GLG MG MA L+ GF + ++ ++ A G A +
Sbjct: 2 ERLGFIGLGRMGQVMAGRLLAAGFPLTVHNRTRARAEALLAGGAAWAETPAEVTARSDLV 61
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
+ILT + V VY G+DG+++ G L I+ STI + + + ++G DAPV
Sbjct: 62 FTILTDDHAVETVYCGRDGLLSTDASGRLFIEMSTIRTSTILSLAGMVDQRGARLLDAPV 121
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SG V A+ L + GGR D ER+ P L V+G + H G G+G KL NM M
Sbjct: 122 SGTVAPAREGQLLVLVGGRTSDLERARPALGVLGRRIIHLGGQGAGTTMKLVLNMTMACF 181
Query: 649 GMATAECMNMGH*NGTRTE 705
A AE + +G G E
Sbjct: 182 WGALAESLAVGQQFGLNIE 200
>UniRef50_A3VLN6 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 293
Score = 104 bits (250), Expect = 2e-21
Identities = 62/187 (33%), Positives = 92/187 (49%), Gaps = 1/187 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V F GLGN+G MA L ++G + ++ S+ + GV A S
Sbjct: 3 VGFAGLGNIGALMAWRLQERGHDLVVWNRSQAKTQSFRDAGVPVAPSPADLARQVDVLCL 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFTDAPVS 471
+T K + V G DG+V + ++++D ST+ P+ +QI + E G + DAPVS
Sbjct: 63 CVTDAKALDAVLFGSDGIVGAGRVPAMIVDHSTVPPDATRQIAARVRAEAGAAWVDAPVS 122
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
GG+ GA LA GG D R+ P+L +G H G GSGQVAK N ++ ++
Sbjct: 123 GGLAGAAAGQLAIFVGGEDADVTRAWPVLTTLGTTVTHLGPTGSGQVAKACNQVIGFLSF 182
Query: 652 MATAECM 672
A AE +
Sbjct: 183 AALAEAL 189
>UniRef50_A1B741 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Paracoccus denitrificans (strain Pd 1222)
Length = 309
Score = 104 bits (249), Expect = 2e-21
Identities = 66/189 (34%), Positives = 92/189 (48%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLG MG MAANL G + D S+ A G T A + +
Sbjct: 3 IGFIGLGKMGRGMAANLQTGGAALVVADLSRTAAEEFTVRGATWAETPADLARDCGIVFT 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
L + V + G G+V G++ +D ST +V +QI KG+ F DAPVSG
Sbjct: 63 SLPTPADVRNAGFGPRGLVEGMAPGTVWLDLSTNSVDVVRQIHAELAPKGIHFIDAPVSG 122
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G GA + LA GG +E ++R LP L+ M + + G IG+G +AKL NNM
Sbjct: 123 GPAGAASGQLAIWCGGEREVYDRCLPWLEKMADQPRYIGDIGAGTIAKLVNNMASTAIIS 182
Query: 655 ATAECMNMG 681
AE ++MG
Sbjct: 183 VLAEALSMG 191
>UniRef50_Q18X68 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Desulfitobacterium hafniense|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Desulfitobacterium hafniense (strain DCB-2)
Length = 298
Score = 103 bits (247), Expect = 4e-21
Identities = 66/188 (35%), Positives = 94/188 (50%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLG MG MA NL+K G + YD + + G A I S
Sbjct: 3 LGFIGLGQMGKHMALNLLKSGEELIVYDQRPASYPEFEQRGARTAAQIRDVAEADIIFCS 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
L +++VV V LG+ G+ + G +++D+STI+ + +I G+ F DAPVSG
Sbjct: 63 -LPNSEVVCQVVLGETGLKKVLRAGQIIVDTSTINYSTTLEIGKQLESVGVEFIDAPVSG 121
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
A+ TL M GG++E FE P L+ K + GQ GSGQ+ KL N +L I
Sbjct: 122 MESRAKEGTLTTMCGGKQELFENVKPYLQCFADKILYMGQPGSGQLTKLINQLLFDINVA 181
Query: 655 ATAECMNM 678
A AE + M
Sbjct: 182 ALAEILPM 189
>UniRef50_A6SUL3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Janthinobacterium sp. Marseille|Rep:
2-hydroxy-3-oxopropionate reductase - Janthinobacterium
sp. (strain Marseille) (Minibacterium massiliensis)
Length = 304
Score = 103 bits (247), Expect = 4e-21
Identities = 62/193 (32%), Positives = 101/193 (52%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+AFLG+G MG MA+ L++ G+ V ++ ++ + A G + A + +
Sbjct: 10 IAFLGIGLMGKPMASRLLQAGYPVTAWNRTRSKADELAPLGASVAERVADAVAAADIVIT 69
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L + +V V D + K G+L+ID S+ + +++ +G+ F DAPVSG
Sbjct: 70 MLEAGPIVAQVI---DAALPGLKHGALVIDMSSTRQSEAQEVHAKLAAQGVRFIDAPVSG 126
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
GV+GA+ +LA MAGG +DF + +L VMG G G GQ+AKL N +++G T
Sbjct: 127 GVVGAEAGSLAIMAGGSAQDFAEAEAVLTVMGRPTL-VGPAGCGQIAKLCNQLIVGGTLN 185
Query: 655 ATAECMNMGH*NG 693
AE + + G
Sbjct: 186 IVAEALLLAQAGG 198
>UniRef50_Q89HA0 Cluster: Oxidoreductase; n=1; Bradyrhizobium
japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum
Length = 313
Score = 103 bits (246), Expect = 6e-21
Identities = 61/192 (31%), Positives = 90/192 (46%), Gaps = 1/192 (0%)
Frame = +1
Query: 106 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 285
D+ +LGLG MG M L+K G+ V ++ S+ + + G S
Sbjct: 23 DERFGYLGLGLMGTPMTRRLLKAGYQVSVWNRSEGKVVPIVEAGARHGASPRDVMAGSDI 82
Query: 286 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP-IALEKGLGFTDA 462
+T V +V G +G+ G L++D S+I P+ + + + G G+ DA
Sbjct: 83 VFMCVTDAAAVEEVIFGAEGLSTAPGAGKLVVDFSSIHPDAARDLATRLKAANGAGWIDA 142
Query: 463 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 642
PVSGG GA+ TLA MAGG D ER P + M + H G G+GQ AKL N +++G
Sbjct: 143 PVSGGTKGAEEGTLAIMAGGDASDIERVRPYVLTMARRFTHMGPTGAGQTAKLCNQVIVG 202
Query: 643 ITGMATAECMNM 678
AE +
Sbjct: 203 CAMAVLAEATRL 214
>UniRef50_Q89R44 Cluster: Oxidoreductase; n=23; Bacteria|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 305
Score = 102 bits (245), Expect = 8e-21
Identities = 60/194 (30%), Positives = 94/194 (48%), Gaps = 1/194 (0%)
Frame = +1
Query: 94 SSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXX 273
S++ ++ +A +GLG+MG MA +L + G V G D S DA+ K+G A +
Sbjct: 4 STSQNQRIAVVGLGSMGFGMATSLKRAGHAVTGCDVSADAVARFVKDGGAGAKTPAEAAR 63
Query: 274 XXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGF 453
S++ + + GKDGV K S+ + S+T+DP+V +++ G +
Sbjct: 64 GADVVVSVVVNAAQTETILFGKDGVAETMPKDSVFLSSATMDPDVARRLAKQLEATGRHY 123
Query: 454 TDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNN 630
DAP+SGG A L +A G F ++ P L M AK + G G G K+ N
Sbjct: 124 LDAPISGGAQRAAQGELTILASGSPAAFAKARPALDAMAAKLYELGDAAGQGAAFKMINQ 183
Query: 631 MLMGITGMATAECM 672
+L G+ A +E M
Sbjct: 184 LLAGVHIAAASEAM 197
>UniRef50_A0LTQ8 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Acidothermus cellulolyticus
11B|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
precursor - Acidothermus cellulolyticus (strain ATCC
43068 / 11B)
Length = 305
Score = 102 bits (245), Expect = 8e-21
Identities = 66/189 (34%), Positives = 93/189 (49%), Gaps = 5/189 (2%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNA-----AAKNGVTPANSIXXXXXXX 279
VA LGLG MG MAA L G + ++ +++ A AK TPA ++
Sbjct: 4 VAVLGLGAMGSAMAARLHDAGAELILWNRTRERAQALGERLGAKVAATPAEAVADVPVAL 63
Query: 280 XXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 459
+ L + V DV+LG DGVVA A+ G ++ + ST++P V + I P KG D
Sbjct: 64 ----TSLADRRAVEDVFLGPDGVVAGARPGLVVAELSTVEPEVARAIAPELRAKGADILD 119
Query: 460 APVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 639
PVSG V A+ L M GG + P+L ++G + FH G +GSG KL N ++
Sbjct: 120 VPVSGSVAVAREGGLTLMVGGEDASLDAIRPVLDIIGRRIFHLGPLGSGAAMKLAVNTVI 179
Query: 640 GITGMATAE 666
A AE
Sbjct: 180 HGLNAALAE 188
>UniRef50_Q84H84 Cluster: Putative oxidoreductase; n=1; Arthrobacter
sp. BP2|Rep: Putative oxidoreductase - Arthrobacter sp.
BP2
Length = 278
Score = 102 bits (244), Expect = 1e-20
Identities = 65/194 (33%), Positives = 100/194 (51%), Gaps = 3/194 (1%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI-XXXXXXXXX 285
K + F+GLG MG MA NL + GF V GYD + + A G+T A ++
Sbjct: 3 KKIGFVGLGTMGLPMAVNLNRAGFEVIGYDAFEGSRQKAIAAGITMAETLKDVAEQADDA 62
Query: 286 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG-LGFTDA 462
S++ +DV LG+DG+++ K +I ST+DP+ ++ E G + A
Sbjct: 63 IVSMVRDYAQNVDVILGQDGLLSANPKNLTIIVMSTLDPDTMNELGQQVEEHGEVRLIAA 122
Query: 463 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLM 639
VSGG GA+ TL+ MA G ++ + P +G+ F+ G + G+ Q AKL NN+++
Sbjct: 123 AVSGGSTGAEAGTLSIMASGAEDVVTAASPYFDAVGSNTFYYGSKPGNSQAAKLVNNLVL 182
Query: 640 GITGMATAECMNMG 681
GI A AE + G
Sbjct: 183 GINMNAVAEGLKFG 196
>UniRef50_Q3DYV4 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Chloroflexus|Rep: NADP oxidoreductase,
coenzyme F420-dependent:6-phosphogluconate
dehydrogenase, NAD-binding - Chloroflexus aurantiacus
J-10-fl
Length = 289
Score = 102 bits (244), Expect = 1e-20
Identities = 63/186 (33%), Positives = 97/186 (52%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+A +GLG MG MA L+K GF V G++ S L+ A G+ P +
Sbjct: 3 IALIGLGLMGRPMARTLLKAGFNVTGWNRSP--LDPALTEGI-PLAATLAEAAQAETLIL 59
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L+ + V ++ D ++ ++G L+ID + DP + +G+G+ DAPVSG
Sbjct: 60 MLSDSTAVAELLSRLDPLL---REGQLIIDMGSSDPRHSQTHATTLANRGIGWVDAPVSG 116
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G GA TLA M GG D ER+ P+L+ +G + H G G+G K+ N +++G+T
Sbjct: 117 GPEGAAAGTLAIMVGGTASDVERAEPILRALG-RPTHVGPPGAGHTVKVINQLIVGLTIQ 175
Query: 655 ATAECM 672
A AE M
Sbjct: 176 AVAEAM 181
>UniRef50_Q94B07 Cluster: Gamma hydroxybutyrate dehydrogenase; n=16;
cellular organisms|Rep: Gamma hydroxybutyrate
dehydrogenase - Arabidopsis thaliana (Mouse-ear cress)
Length = 289
Score = 101 bits (242), Expect = 2e-20
Identities = 62/197 (31%), Positives = 95/197 (48%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V FLGLG MG M+ NL+K GF V ++ + + ++G + S +
Sbjct: 3 VGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIA 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L+ L V K GV+ +G ID ST+D +I KG F + PVSG
Sbjct: 63 MLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSG 122
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
A++ L +A G K FE S+P V+G + F+ GQ+G+G KL NM+MG
Sbjct: 123 SKKPAEDGQLIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNMIMGSMMN 182
Query: 655 ATAECMNMGH*NGTRTE 705
A +E + + +G ++
Sbjct: 183 AFSEGLVLADKSGLSSD 199
>UniRef50_A5VEA3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Sphingomonas wittichii RW1|Rep:
2-hydroxy-3-oxopropionate reductase - Sphingomonas
wittichii RW1
Length = 264
Score = 101 bits (241), Expect = 2e-20
Identities = 59/197 (29%), Positives = 97/197 (49%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLG G +A NL+ G + G+D + L+ G T A S
Sbjct: 3 IGFIGLGVQGLPLALNLLDGGHELHGFDVRPEPLDELRDRGGTVAASPAELGAACEVVMI 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+ S++ V DV G+DGV+A A+ G +++ S++ + + ++G+ DAPVSG
Sbjct: 63 CVVSDQQVRDVLAGEDGVLASARPGLIVVLHSSVSTDTIAEAAKATRDRGVVLVDAPVSG 122
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G GA+ T++FM GG + +R PL ++ G G G+ +AKL + + + M
Sbjct: 123 GAQGARARTMSFMVGGEEAALDRCQPLFELSGPNILRTGPAGTATLAKLAHQVAIIGNIM 182
Query: 655 ATAECMNMGH*NGTRTE 705
A AE + +G G E
Sbjct: 183 AMAEAVRLGTAGGLSAE 199
>UniRef50_Q84VC8 Cluster: Gamma hydroxybutyrate dehydrogenase-like
protein; n=3; Magnoliophyta|Rep: Gamma hydroxybutyrate
dehydrogenase-like protein - Oryza sativa subsp.
japonica (Rice)
Length = 293
Score = 101 bits (241), Expect = 2e-20
Identities = 61/193 (31%), Positives = 92/193 (47%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V FLGLG MG MAANL++ GF V ++ + G + +
Sbjct: 3 VGFLGLGIMGKAMAANLLRHGFRVTVWNRTLSKCQELVALGAAVGETPAAVVAKCRYTIA 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L+ L V KDGV+ +G +D ST+D +I +KG F +APVSG
Sbjct: 63 MLSDPSAALSVVFDKDGVLEQIGEGKGYVDMSTVDAATSCKISEAIKQKGGAFVEAPVSG 122
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
A++ L +A G K ++ +P V+G K F G+IG+G KL NM+MG
Sbjct: 123 SKKPAEDGQLVILAAGDKVLYDDMVPAFDVLGKKSFFLGEIGNGAKMKLVVNMIMGSMMN 182
Query: 655 ATAECMNMGH*NG 693
A +E +++ +G
Sbjct: 183 ALSEGLSLADNSG 195
>UniRef50_A5VBF0 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=1; Sphingomonas wittichii RW1|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Sphingomonas wittichii RW1
Length = 298
Score = 100 bits (240), Expect = 3e-20
Identities = 64/192 (33%), Positives = 92/192 (47%), Gaps = 1/192 (0%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+ +AFLG+G MG MAA L+ G + ++ S D L G
Sbjct: 3 QRMAFLGIGLMGRPMAARLLDSGHELALWNRSADKLAPLVAAGGRACAIPAEAVEGAAVV 62
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG-LGFTDAP 465
LT V V G+ G G+L++D STI P+ + E G + D P
Sbjct: 63 CLCLTDADAVEQVMFGEGGAARALAPGALVVDFSTIGPDATRGFAKRLAETGDAQWLDCP 122
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 645
VSGGV GA+ TLA +AGG +R PLL ++ A+ G +G+GQ AKL N +++
Sbjct: 123 VSGGVAGAEAGTLAILAGGDAAAIDRVRPLLALLSARVTRMGGVGAGQAAKLCNQLIVAT 182
Query: 646 TGMATAECMNMG 681
+A AE M++G
Sbjct: 183 NMLAIAEAMHVG 194
>UniRef50_A5GPC0 Cluster: Hydroxyacid dehydrogenase/reductase family
protein; n=14; Cyanobacteria|Rep: Hydroxyacid
dehydrogenase/reductase family protein - Synechococcus
sp. (strain WH7803)
Length = 302
Score = 100 bits (240), Expect = 3e-20
Identities = 60/195 (30%), Positives = 103/195 (52%), Gaps = 6/195 (3%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+AF+GLG +G +AANL + G++++ + S+ A N + + PA +
Sbjct: 12 LAFVGLGALGLPIAANLHRAGYSLQVHTRSRSAENDPSLHQGDPAAATLCCASPADAVQG 71
Query: 295 -----ILTSNKVVLDVYL-GKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFT 456
+ S+ ++ L G +G +GSL+ID STI P+ +++ +G+ +
Sbjct: 72 CQALVLCVSDDAAVEAVLWGDNGAGPALAEGSLVIDCSTISPSTSQRMARRLAHRGVRYL 131
Query: 457 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 636
DAPV+GG GA+ TL + GG D +R++P+L+ +G H G +GSGQ K N +L
Sbjct: 132 DAPVTGGTEGAKAGTLTVLCGGSDADLDRAMPVLETIGGSIHHFGAVGSGQQVKAVNQVL 191
Query: 637 MGITGMATAECMNMG 681
+ + A AE + +G
Sbjct: 192 VAGSYAAVAEAIALG 206
>UniRef50_A0G5G5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 306
Score = 100 bits (240), Expect = 3e-20
Identities = 61/191 (31%), Positives = 91/191 (47%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+ + F+GLGNMGG M LV G +V GYD + + + AA G A+SI
Sbjct: 4 ERIGFIGLGNMGGRMTRRLVDAGISVLGYDTAPERVKAA---GAQAASSIADVMKFADVV 60
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
L +KVV V G GV+AH + +++D ST + ++ + G+ + DA +
Sbjct: 61 MMSLPDSKVVEAVVEGDGGVLAHCRARQIVVDLSTAAASSTIRLARRFTQSGVQYVDAGI 120
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SGG A+ L M GG + + +K H G+ G+G KL NN L ++
Sbjct: 121 SGGAAAAEKGALTLMVGGDASAVDALKWAFAPISSKVAHMGESGAGHTTKLLNNFLNAVS 180
Query: 649 GMATAECMNMG 681
A+AE M G
Sbjct: 181 LSASAEVMVAG 191
>UniRef50_A0FZ96 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phymatum STM815|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phymatum STM815
Length = 305
Score = 99.5 bits (237), Expect = 7e-20
Identities = 59/190 (31%), Positives = 97/190 (51%), Gaps = 1/190 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ ++GLG MGG +A +L+ K + + +D ++ A+ A + G T A +
Sbjct: 3 IGYIGLGAMGGALARHLIGK-YPLSVFDLNRKAVEAFVELGATAAATPAELARNSDVVLL 61
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
L + V V G DG V G ++ID ++ P + + G+ DAPVSG
Sbjct: 62 CLPRSSDVHSVLFGPDGAVEGLSDGKIVIDQTSGVPAETRDFARQLADIGVALFDAPVSG 121
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLMGITG 651
+ A T++ +A G K+ FE++LP+L+ + FHCG+ +G+GQ K NNM+
Sbjct: 122 AMATAIAGTISIIASGPKDAFEKTLPVLQSISPNVFHCGERVGNGQTMKTVNNMMNVSCR 181
Query: 652 MATAECMNMG 681
+AT E + MG
Sbjct: 182 LATLEVVAMG 191
>UniRef50_Q39FA8 Cluster: 2-hydroxy-3-oxopropionate reductase; n=22;
Burkholderiales|Rep: 2-hydroxy-3-oxopropionate reductase
- Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 287
Score = 99.1 bits (236), Expect = 9e-20
Identities = 61/188 (32%), Positives = 91/188 (48%), Gaps = 3/188 (1%)
Frame = +1
Query: 139 MGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILTSNKVV 318
MG M +L+ G V ++ S+D A K+G + + + V
Sbjct: 1 MGAPMIRHLLAAGHRVSVWNRSRDKAEALVKDGAQVVGTPRELAERVDTVFVCVLDGRAV 60
Query: 319 LDVYLGKDGVV---AHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGA 489
DV G+ G++ A A++ ++D S+I P + A G+G+ DAPVSGGV GA
Sbjct: 61 GDVVFGEHGLLSGDAAARRLQRIVDHSSIPPAATRDYAARATALGVGWVDAPVSGGVPGA 120
Query: 490 QNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAEC 669
Q TLA MAGGR D + PL+ ++ H G G+GQ AKL N ++ T A AE
Sbjct: 121 QAGTLAVMAGGRAADLDAVRPLIDTYASRITHMGDAGAGQTAKLCNQAIVTATVTAIAEA 180
Query: 670 MNMGH*NG 693
+ + +G
Sbjct: 181 VGLAQASG 188
>UniRef50_A3WAC4 Cluster: Dehydrogenase; n=4; Bacteria|Rep:
Dehydrogenase - Erythrobacter sp. NAP1
Length = 301
Score = 99.1 bits (236), Expect = 9e-20
Identities = 63/204 (30%), Positives = 100/204 (49%), Gaps = 6/204 (2%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYD----PSKDALNAAAKNG-VTPANS-IXXXX 270
K +AFLGLG MGG M +LV+ G GY+ +++ + G V P S
Sbjct: 5 KRIAFLGLGVMGGPMWGHLVRAGHEATGYNRNFAKAEEWSDRLGDEGLVAPIESDAATAV 64
Query: 271 XXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG 450
+ L ++ V V G++GV+A K+G+ ID +++ P + ++I GL
Sbjct: 65 RGKDVVLACLGNDDDVASVLFGENGVLAAMKRGATFIDHTSVSPGLARRIADECERLGLH 124
Query: 451 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNN 630
DAPVSGG GA+N L+ M GG +E + P+++ A+ H G+ G+GQ AK N
Sbjct: 125 AVDAPVSGGQAGAENGKLSIMCGGSEEAMASAQPVMQAYAARIVHIGEAGAGQTAKAINQ 184
Query: 631 MLMGITGMATAECMNMGH*NGTRT 702
+ + +E + + G T
Sbjct: 185 VCIAGVLAGLSEGVRLAQATGVDT 208
>UniRef50_Q47AR2 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Dechloromonas aromatica RCB|Rep: NADP
oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding - Dechloromonas aromatica (strain RCB)
Length = 287
Score = 98.7 bits (235), Expect = 1e-19
Identities = 67/197 (34%), Positives = 96/197 (48%), Gaps = 4/197 (2%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTV----RGYDPSKDALNAAAKNGVTPANSIXXXXXXXX 282
+ F+GLG MG MA NL+K G V R + + L+A AK +PA +
Sbjct: 3 IGFIGLGIMGRPMALNLIKGGHQVTVWARRAESMQPLLDAGAKGAASPAEAARGNELVI- 61
Query: 283 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 462
S++ V +V G V + + G + +D STI P ++I G+ F DA
Sbjct: 62 ---SMVADAPDVAEVMRG---VASAGESGLVAVDMSTIAPAAARRIGEDLAAAGIDFIDA 115
Query: 463 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 642
PVSGG +GA +L+ MAGG F ++ P + MG H G G+GQVAK N ++ G
Sbjct: 116 PVSGGEVGAIAGSLSIMAGGSDAAFAKAKPAFECMGKNIVHVGASGAGQVAKAANQIVTG 175
Query: 643 ITGMATAECMNMGH*NG 693
+ +A AE NG
Sbjct: 176 MGVLAVAEAFAFAAKNG 192
>UniRef50_A3K497 Cluster: Probable 6-phosphogluconate dehydrogenase
protein; n=1; Sagittula stellata E-37|Rep: Probable
6-phosphogluconate dehydrogenase protein - Sagittula
stellata E-37
Length = 298
Score = 98.7 bits (235), Expect = 1e-19
Identities = 61/195 (31%), Positives = 97/195 (49%), Gaps = 3/195 (1%)
Frame = +1
Query: 106 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 285
DK + F+GLGNMG MA +LV+ GF V YD + A A+ +
Sbjct: 3 DKLIGFIGLGNMGTAMARHLVRGGFEVLAYDIDAEKRAAFAEETGMRNPATVAELAEATV 62
Query: 286 XXSILTSNKVVLDVYL--GKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTD 459
++L + +V V G+ G++ + G+L+ID+++ P +++ + +G D
Sbjct: 63 LLTMLPNGAIVRKVLDEGGEAGLLGQMQPGTLMIDTTSSPPEATRELAAVLNARGCHLVD 122
Query: 460 APVSGGVMGAQNATLAFMAGGRKED-FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 636
APVSG GA+ A L FM G + ER+ +L +G + FH G +G+G K NN +
Sbjct: 123 APVSGARAGAEAADLVFMIGCDDDAVLERTRAVLSCLGNRLFHLGPVGAGHAMKALNNYV 182
Query: 637 MGITGMATAECMNMG 681
+A AE M +G
Sbjct: 183 SAAGYVAAAEAMIIG 197
>UniRef50_A0JXR2 Cluster: 2-hydroxy-3-oxopropionate reductase; n=2;
Arthrobacter|Rep: 2-hydroxy-3-oxopropionate reductase -
Arthrobacter sp. (strain FB24)
Length = 333
Score = 98.7 bits (235), Expect = 1e-19
Identities = 67/200 (33%), Positives = 97/200 (48%), Gaps = 5/200 (2%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
K F+GLG MGG MAANL+K G+ V G++ S AL+ A G A +
Sbjct: 16 KRAGFVGLGLMGGPMAANLLKAGWNVTGWNRSAAALDDLAARGGMRAADVASLRDEPVII 75
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKG--SLLIDSSTIDPNVPKQ--IFPIALEKGLGFT 456
+L + D G A G ++++ S++ P + + A +G
Sbjct: 76 F-MLPDLSYIEDAAAGLLAGWADEPPGPGTVVVVMSSVSPAAVRDFGVKVSAASRGNAVV 134
Query: 457 -DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNM 633
DAPVSGG GA++ TLA M G ++DF+R LPL MG G +GSG +AK N +
Sbjct: 135 VDAPVSGGTKGAEDGTLAIMVGAGEQDFQRLLPLFNAMGGTVRRLGPLGSGSLAKACNQL 194
Query: 634 LMGITGMATAECMNMGH*NG 693
++G T A AE + +G
Sbjct: 195 IVGTTTAALAEAAELAERSG 214
>UniRef50_Q9L7S0 Cluster: Uncharacterized oxidoreductase yihU; n=24;
Gammaproteobacteria|Rep: Uncharacterized oxidoreductase
yihU - Salmonella typhimurium
Length = 298
Score = 98.7 bits (235), Expect = 1e-19
Identities = 59/184 (32%), Positives = 86/184 (46%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+AF+GLG MG MA+NL+K+G + +D + DA+ G PA+S +
Sbjct: 4 IAFIGLGQMGSPMASNLLKQGHQLSVFDVNPDAVQRLVDKGAQPASSPAQATIGAEFVIT 63
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L + +V V G+ GV + +L+ID STI P + KG D P+
Sbjct: 64 MLPNGDLVRSVLFGEQGVCETLSREALVIDMSTIHPLQTDNLIADMQSKGFSMMDVPIGR 123
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
A TL +AGG E ER+ P+L MG + + G G G KL NN +
Sbjct: 124 TSDNAITGTLLLLAGGTAEQVERATPVLMAMGNELVNTGGPGMGIRVKLINNYMSIALNA 183
Query: 655 ATAE 666
+AE
Sbjct: 184 LSAE 187
>UniRef50_Q8EW87 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Mycoplasma penetrans|Rep: 3-hydroxyisobutyrate
dehydrogenase - Mycoplasma penetrans
Length = 288
Score = 98.3 bits (234), Expect = 2e-19
Identities = 59/188 (31%), Positives = 93/188 (49%), Gaps = 1/188 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ ++G G MG M L G + Y+ + + +N + SI +
Sbjct: 3 ITWIGTGIMGKAMLNRLASHGHIIHAYNRTYEKMNDLNHPNILKFRSIKDAVKDTNIIMT 62
Query: 295 ILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
++ VLD+YL + G+ + + ID +T PN Q+ + KG+ DAPV+
Sbjct: 63 MVGYPSDVLDIYLNDEYGIFNYVSSEQICIDFTTSSPNFAVQLANNS--KGIKVLDAPVT 120
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
GG +GA N TL+ M GG E F++ +LK++G K + G G GQ AKL N +L+ +
Sbjct: 121 GGDIGALNGTLSIMVGGDFETFKKVESILKILGNKINYFGSAGKGQHAKLFNQILVAVNT 180
Query: 652 MATAECMN 675
ATAE +N
Sbjct: 181 FATAEVLN 188
>UniRef50_A3H5R1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Caldivirga maquilingensis IC-167
Length = 295
Score = 97.9 bits (233), Expect = 2e-19
Identities = 61/191 (31%), Positives = 95/191 (49%), Gaps = 1/191 (0%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKD-ALNAAAKNGVTPANSIXXXXXXXXXX 288
NV +GLG MG +A NL G + ++ + A+ A +N V N+
Sbjct: 3 NVGLIGLGTMGWRIAKNLKDDGLLIGVFNRTMSKAIKFAEENKVNVFNNPAELARNVDVV 62
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
SI++ + V + LG++GV+ K+GSL+I+ STI P+ ++ EKG DAP+
Sbjct: 63 LSIVSDDDAVKSIMLGENGVINGIKQGSLVIEMSTISPSTSIELANKIKEKGGLMVDAPI 122
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
G + + + GG +E +ER+ ++K H G G G AKL NN L+G
Sbjct: 123 IGTSILIEKREAVVLIGGEREAYERAYEVVKHFARYVVHVGPNGYGLYAKLINNALLGSY 182
Query: 649 GMATAECMNMG 681
A AE +N+G
Sbjct: 183 VAALAEVVNLG 193
>UniRef50_Q39MY1 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Burkholderia sp. 383|Rep: 3-hydroxyisobutyrate
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 303
Score = 96.3 bits (229), Expect = 7e-19
Identities = 63/191 (32%), Positives = 93/191 (48%), Gaps = 1/191 (0%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
++ FLGLG MG MA L+ + + YDPS A+ G S
Sbjct: 6 DIGFLGLGKMGAPMAERLLGQACRLHVYDPSAQAVAPFVDGGAVAHASPRAVADAASIVF 65
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
+ L + V L V LG DGVV H L ++ STI ++ ++I ++G+ DAPVS
Sbjct: 66 ACLPNRDVSLAVGLGPDGVV-HGSAVRLYVEMSTIGQDMIERIGEGLAQRGIDIVDAPVS 124
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGIT 648
GG A+ TLA + G E+ PLL+ +G + F G + G Q+ K+ NN++M
Sbjct: 125 GGPSAARAGTLAMLVSGMPSAVEQVSPLLERIGKEVFPMGDRPGMAQIMKIVNNVVMAAN 184
Query: 649 GMATAECMNMG 681
+ AE + MG
Sbjct: 185 LVVCAEGLAMG 195
>UniRef50_Q606G9 Cluster: Oxidoreductase, Gfo/Idh/MocA family; n=6;
Proteobacteria|Rep: Oxidoreductase, Gfo/Idh/MocA family
- Methylococcus capsulatus
Length = 289
Score = 95.9 bits (228), Expect = 9e-19
Identities = 58/188 (30%), Positives = 93/188 (49%), Gaps = 1/188 (0%)
Frame = +1
Query: 121 FLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPA-NSIXXXXXXXXXXXSI 297
F+GLG MG MA NL + G ++ + + A A TPA ++ +
Sbjct: 5 FVGLGAMGLGMARNLRRAGLLAGVWNRTPEKARAFAAETGTPAWATLTEMAPACDVIVTC 64
Query: 298 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 477
++++ VL+V + + G++++D ST+ ++ + + G F DAPVSGG
Sbjct: 65 VSADADVLEVIAA---LTPGLRPGAVIVDCSTVGVATARRAAEVVRQAGGDFLDAPVSGG 121
Query: 478 VMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMA 657
V GA++ TLA M GGR E E+ P+L MG++ H G G+GQ K N ++ A
Sbjct: 122 VEGARDGTLALMIGGRAETVEKVRPVLAAMGSRLMHMGDTGAGQATKAVNQVMCAGINQA 181
Query: 658 TAECMNMG 681
E + G
Sbjct: 182 VTEALAFG 189
>UniRef50_Q0RCX7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Frankia alni ACN14a|Rep: 3-hydroxyisobutyrate
dehydrogenase - Frankia alni (strain ACN14a)
Length = 313
Score = 95.9 bits (228), Expect = 9e-19
Identities = 61/189 (32%), Positives = 90/189 (47%), Gaps = 2/189 (1%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKD--ALNAAAKNGVTPANSIXXXXXXXXXX 288
V F+GLG MG MA +L + GF Y+ ++ A +A + G A
Sbjct: 3 VGFVGLGTMGFPMAGHLARAGFDTVVYNRTETTAARWSAVQRGRVAATPAQAAAGSDVVC 62
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
+ + V V LG DG + G+ ++D +T + +I A E G+GF DAPV
Sbjct: 63 VCVGADDDV-RSVLLGPDGALGALAPGATIVDHTTTSAELAVEIAARAAEVGVGFVDAPV 121
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SGG GA+ L+ M GG + ER P+L GA G +G+GQ+ K+ N +L+
Sbjct: 122 SGGQAGAEAGRLSVMCGGEVDTVERVRPVLAAYGATITRIGPVGTGQLTKMVNQILVAGA 181
Query: 649 GMATAECMN 675
AE +N
Sbjct: 182 IEGAAEALN 190
>UniRef50_A5P0V0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=3; Rhizobiales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Methylobacterium sp. 4-46
Length = 299
Score = 95.9 bits (228), Expect = 9e-19
Identities = 65/193 (33%), Positives = 93/193 (48%), Gaps = 5/193 (2%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
VAF+GLG MG MA NLV KGF VRGYD ++ A A+ G A+++
Sbjct: 6 VAFVGLGAMGLPMAQNLVAKGFPVRGYDVRPESRAALARAGGEAADTLRAAAAGAGALVL 65
Query: 295 ILTSNKVVLDVYLG----KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 462
++ + V G +G + + +I +T P + + G F DA
Sbjct: 66 MVVNAAQAEAVLFGGGAPAEGALEVLAPDAAVILMATCPPQAVEGLAARVAAAGRRFVDA 125
Query: 463 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLM 639
PVSGGV+GA+ +L MA E F PLL +GA+ FH G + G G K N +L
Sbjct: 126 PVSGGVVGAEAGSLTVMAAAPAEVFGAVRPLLDAVGARIFHVGTRPGQGATVKAVNQLLC 185
Query: 640 GITGMATAECMNM 678
G+ A AE +++
Sbjct: 186 GVHIAAAAEALSL 198
>UniRef50_A7PEG7 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr11 scaffold_13, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 348
Score = 95.5 bits (227), Expect = 1e-18
Identities = 68/208 (32%), Positives = 100/208 (48%), Gaps = 1/208 (0%)
Frame = +1
Query: 73 TAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPAN 252
TAA S ++ V ++G G MG M A+L+K G+TV ++ + G A+
Sbjct: 37 TAAVAEPVSPSNTRVGWIGTGVMGRSMCAHLMKAGYTVTIFNRTISKAQPLLDMGAHHAS 96
Query: 253 SIXXXXXXXXXXXSILTSNKVVLDVYLG-KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPI 429
S SI+ V V L G ++ + G +L+D +T DP++ +I
Sbjct: 97 SPLALASQSDVVFSIVGFPSDVRSVLLDPSSGALSGLRPGGVLVDMTTSDPSLAAEIASS 156
Query: 430 ALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQ 609
A +G DAPVSGG GA+NATLA AGG + R PL +G K + G G GQ
Sbjct: 157 AASRGCFSVDAPVSGGDRGAKNATLAIFAGGDESVVRRLNPLFSHLG-KVNYMGGPGKGQ 215
Query: 610 VAKLTNNMLMGITGMATAECMNMGH*NG 693
AKL N +++ T + E M + +G
Sbjct: 216 YAKLANQIIIASTMLGLIEGMMYAYKSG 243
>UniRef50_Q01QM2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxyisobutyrate
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 298
Score = 95.1 bits (226), Expect = 2e-18
Identities = 63/189 (33%), Positives = 91/189 (48%), Gaps = 2/189 (1%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAA--KNGVTPANSIXXXXXXXXX 285
N+ FLGLG MG MA NL++ G V + + D A + GV A
Sbjct: 3 NLGFLGLGLMGYPMARNLLRAGHNVAVWSHTSDKARKLADEEKGVFCATPRDVGAGADVV 62
Query: 286 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 465
+ + +V LG G++ + G++++D STI ++I K + F DAP
Sbjct: 63 FLCV-GDTAMAREVILGGQGLIQGLRAGAVVVDCSTIAVADSREIGAALKAKSVDFLDAP 121
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 645
V+G GA++ L FM GG + F + PLL MG K + CG G G AKLT N+++
Sbjct: 122 VTGSTPGAESGNLTFMIGGDEAVFSKIRPLLDPMGKKIYFCGGAGMGLQAKLTQNLVLSN 181
Query: 646 TGMATAECM 672
MA E M
Sbjct: 182 ILMAFNEGM 190
>UniRef50_A1R2J4 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Arthrobacter aurescens TC1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Arthrobacter aurescens (strain TC1)
Length = 332
Score = 95.1 bits (226), Expect = 2e-18
Identities = 62/191 (32%), Positives = 86/191 (45%), Gaps = 2/191 (1%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLGNMG M NL GF + D K++ NG A +
Sbjct: 26 IGFIGLGNMGSGMTRNLQAAGFHLVVNDVRKESAAELLANGAEWAEDAAAVAAGSDVVIT 85
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L + K V V +G G++A G +D ST P V ++ +G+ DAPVSG
Sbjct: 86 MLPTPKHVETVAMGPGGILAGMPDGGTWVDMSTSVPEVANRVREAGSVRGIRVLDAPVSG 145
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQ--FHCGQIGSGQVAKLTNNMLMGIT 648
+GA N L GG D ER P+ + MG + H G G+G KL N L
Sbjct: 146 MSVGAANGMLQIFVGGEPADVERLRPVFEAMGDPERILHVGGHGAGYAVKLMINQLWFSH 205
Query: 649 GMATAECMNMG 681
+ATAE ++ G
Sbjct: 206 LVATAEVLSTG 216
>UniRef50_A6EH53 Cluster: Putative uncharacterized protein; n=1;
Pedobacter sp. BAL39|Rep: Putative uncharacterized
protein - Pedobacter sp. BAL39
Length = 292
Score = 94.3 bits (224), Expect = 3e-18
Identities = 54/195 (27%), Positives = 90/195 (46%)
Frame = +1
Query: 121 FLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSIL 300
++GLGNMG MA ++ KG+++ Y+ + G A + ++
Sbjct: 17 WIGLGNMGVPMAGQVLNKGYSLTVYNRTLSKTEPLVAQGAKVAGTPGELIAATDIVFLMV 76
Query: 301 TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGV 480
+ + V ++ G DG+++ G ++++ ST+ P + ++ G+ + DAPVSG V
Sbjct: 77 SDDHAVASLFEGADGLLSKELHGKVIVNMSTVSPAISIKMAAACSAVGIEYLDAPVSGSV 136
Query: 481 MGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAT 660
A + L M GG ++ F + PLL MG H G G G AKL N L+ I
Sbjct: 137 KQATDGQLVIMVGGEEQAFHAAEPLLSCMGKLVMHLGASGIGNKAKLAINTLLAIYTEGL 196
Query: 661 AECMNMGH*NGTRTE 705
AE + + TE
Sbjct: 197 AEIVTFSRKHQINTE 211
>UniRef50_A3X9R7 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=2; Rhodobacterales|Rep: 3-hydroxyisobutyrate
dehydrogenase family protein - Roseobacter sp. MED193
Length = 300
Score = 94.3 bits (224), Expect = 3e-18
Identities = 55/188 (29%), Positives = 91/188 (48%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ +GLG MGG + L+ + + +D +A AA G A+S+ S
Sbjct: 17 IGLVGLGAMGGGYLSRLMAQNCDLMCFDAMPEARARAAAAGAKVADSLADFSACDTVILS 76
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+ ++ + + G + KKGS+++D+ST +P+ K++ A G F D PVSG
Sbjct: 77 L--PKAAIVSAVMEELG--PYLKKGSIVVDTSTSEPDTTKRLAAAAESNGYTFLDGPVSG 132
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G +GA+ T+ + GG + F + PLL+ M K H G G+G K+ NN+L +
Sbjct: 133 GPLGARTGTMTMVVGGDEAGFTKVRPLLEKMTGKLVHIGPSGAGHTVKIANNLLCAANLV 192
Query: 655 ATAECMNM 678
+E M
Sbjct: 193 LMSEMAQM 200
>UniRef50_Q0URA2 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 325
Score = 94.3 bits (224), Expect = 3e-18
Identities = 79/217 (36%), Positives = 106/217 (48%), Gaps = 22/217 (10%)
Frame = +1
Query: 97 SNTDKNVAFLGLGNMGGFMAANLVK---KGFTVRGYDPSKDALNAAAKN--GVTPANSIX 261
S +K VAF+GLG MG MA NL K T+ D S DAL + G P +++
Sbjct: 2 SPPEKTVAFIGLGVMGYPMALNLRKGLDDSHTLLVCDVSSDALARFQNDAKGHGPVSTVD 61
Query: 262 XXXXXXXXXXSILT---SNKVVLDVYLGKD-GVVAHAKKGS------LLIDSSTIDPN-- 405
+++T + V VYL G++A A+ S L+++ TI+ +
Sbjct: 62 GGYQAVQLADTVITMLPDSNAVKKVYLDPSTGILAGAEANSGTKSDKLIMECGTIETSTI 121
Query: 406 --VPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAG-GRKEDFERSLPLLKVMGAK 576
V K + L F DAPVSGG MGAQ+ TLAFMAG K F R L MG
Sbjct: 122 LEVAKATSSSKAAENLTFVDAPVSGGPMGAQDGTLAFMAGANNKAIFPRVKGYLSHMGKP 181
Query: 577 Q--FHCGQIGSGQVAKLTNNMLMGITGMATAECMNMG 681
F CG IG+G K+ NN L IT +A +E +N+G
Sbjct: 182 DAIFLCGDIGAGTAFKVINNYLSAITSLAASEALNIG 218
>UniRef50_A3JU55 Cluster: Predicted dehydrogenase, with
NAD(P)-binding Rossmann-fold domain; n=2; Bacteria|Rep:
Predicted dehydrogenase, with NAD(P)-binding
Rossmann-fold domain - Rhodobacterales bacterium
HTCC2150
Length = 302
Score = 93.9 bits (223), Expect = 4e-18
Identities = 58/182 (31%), Positives = 86/182 (47%), Gaps = 1/182 (0%)
Frame = +1
Query: 124 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILT 303
+GLG+MG +A NL+K GF G D + + A + G A + ++
Sbjct: 6 IGLGDMGSGLAKNLLKAGFETTGIDMKPERMAAFVEMGGRAAVDVADVGANADAVFVMVM 65
Query: 304 SNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVM 483
+ V V G+ G++AH KG +I S+TI P ++I + G+ D PVSGG
Sbjct: 66 NGDQVKSVLFGEGGLLAHMPKGGAVILSATIKPVEAEEIGAAMADSGIHLIDTPVSGGFP 125
Query: 484 GAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITGMAT 660
GAQ TL MA G E + P+++ + A + G + G GQ K L+G AT
Sbjct: 126 GAQGGTLTMMAAGVDEVLDTYAPVMEAVSATIWCVGTEAGQGQTVKACLQSLLGAMFSAT 185
Query: 661 AE 666
E
Sbjct: 186 FE 187
>UniRef50_Q4PCH4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 366
Score = 93.9 bits (223), Expect = 4e-18
Identities = 77/246 (31%), Positives = 117/246 (47%), Gaps = 33/246 (13%)
Frame = +1
Query: 55 STQC-LYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKK--------GFTVRGYDPSK 207
+T+C L+ RR + K + F+GLG MG MA NL+ K T +D +
Sbjct: 4 TTRCMLHHTIRRCVPHDRSKTIGFIGLGAMGKEMANNLLSKTLASNPDPAVTFVVHDAFE 63
Query: 208 DALNA--AAKNGVTP------ANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGV----- 348
++ A + P A+S ++L S+ V VY ++G+
Sbjct: 64 QSITRFLTANTSLYPNRNILAASSPAGIAKLSGTIVTMLPSSPQVESVYTHENGILDGLE 123
Query: 349 ------VAHAKKGSLLIDSSTIDPNVPKQ----IFPIALEKGLGFTDAPVSGGVMGAQNA 498
V A+ +L ID +T+DP+V Q I DAPVSGGV+GA A
Sbjct: 124 SFQAAAVDDAQAKTLCIDCTTLDPDVAVQTATAIKNANANGAFDMIDAPVSGGVVGANAA 183
Query: 499 TLAFMAGGRKED-FERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMN 675
TL+FM G F + P L +MG++ HCG+ G+G +AK+ NN+L+GI+ + E M
Sbjct: 184 TLSFMVGSDSSTTFASAEPYLSLMGSRAVHCGKNGNGLIAKIANNLLLGISMLGVTEAML 243
Query: 676 MGH*NG 693
+G +G
Sbjct: 244 LGTAHG 249
>UniRef50_A1WM48 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Verminephrobacter eiseniae EF01-2|Rep:
3-hydroxyisobutyrate dehydrogenase - Verminephrobacter
eiseniae (strain EF01-2)
Length = 301
Score = 93.5 bits (222), Expect = 5e-18
Identities = 60/187 (32%), Positives = 84/187 (44%)
Frame = +1
Query: 121 FLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSIL 300
F+GLGNMGG M L+ G TV +D AL A +G +S L
Sbjct: 9 FIGLGNMGGPMVKRLLHAGHTVLVFDRDAAALARAVADGAQARSSALDVADAAATIFLSL 68
Query: 301 TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGV 480
V V +DG++ K+ ++D STI P +G+ + D+PVSGG+
Sbjct: 69 PDGPAVQHVISAQDGLL-QGKRVKCVVDLSTIGPRAAVAASQALGARGIAYVDSPVSGGI 127
Query: 481 MGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAT 660
GA+ TLA M + ++ P+LK G + G GQ KL NN+L T
Sbjct: 128 GGAERGTLAVMTACPQPLYDELAPVLKNFGRLFYMGAGPGLGQTMKLANNLLSAAAVAIT 187
Query: 661 AECMNMG 681
+E M MG
Sbjct: 188 SEAMAMG 194
>UniRef50_Q1IQE6 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 282
Score = 93.1 bits (221), Expect = 6e-18
Identities = 61/174 (35%), Positives = 87/174 (50%), Gaps = 1/174 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPS-KDALNAAAKNGVTPANSIXXXXXXXXXXX 291
VAFLGLG MG MAANL K G V ++ + KD A TPA +
Sbjct: 3 VAFLGLGIMGRPMAANLAKAGNEVTVWNRTPKDVEGAHVAK--TPAEAAKHADVVWMC-- 58
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
++ V V G GV + G +++DSSTI P + KG + DAP++
Sbjct: 59 --VSDTNAVERVLFGDGGVEPVLRAGMVVVDSSTISPVETLKFAERVRAKGADYIDAPIT 116
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNM 633
G +GA++A L FM G + E ++ PL MG K H G++G GQ +K++ N+
Sbjct: 117 GSKIGAESAQLIFMVGAKDETLKKLEPLFLQMGKKIVHMGEVGKGQASKISLNL 170
>UniRef50_A3WMG5 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Idiomarina baltica OS145|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase - Idiomarina
baltica OS145
Length = 284
Score = 93.1 bits (221), Expect = 6e-18
Identities = 58/189 (30%), Positives = 95/189 (50%), Gaps = 1/189 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+AFLGLG MG MA +L+ G ++ ++ ++ + G A++ +
Sbjct: 4 IAFLGLGAMGIRMAQHLIDAGHSLTVWNRTESRAEPLLEQGAQWADTPAEAAQGAELVIA 63
Query: 295 ILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
++ + V+L + G ++ I+SST+ + K++ A ++G +APVS
Sbjct: 64 MVRDDDASAAVWLDEQTGAFKGMSDNAIAIESSTLSVDWVKELAQQAQQRGKQLIEAPVS 123
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
G AQNA L ++ GG R+ P+L +MG K H G++GSG +AKL N LMGI
Sbjct: 124 GSRPQAQNAELVYLVGGDAHLVNRAEPVLSLMGKKVNHTGEMGSGALAKLVTNTLMGIQV 183
Query: 652 MATAECMNM 678
AE + M
Sbjct: 184 TTIAELIGM 192
>UniRef50_A7IE35 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Xanthobacter sp. (strain Py2)
Length = 330
Score = 92.7 bits (220), Expect = 8e-18
Identities = 55/186 (29%), Positives = 86/186 (46%), Gaps = 1/186 (0%)
Frame = +1
Query: 118 AFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSI 297
A +GLG+MG MA +L + GF V G+D + A+ A G A+S S+
Sbjct: 36 AVIGLGSMGYGMAQSLKRAGFDVAGFDVNAAAVERFAAEGGRGASSPAEAARDADVVVSV 95
Query: 298 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 477
+ + + G DGV G++ + S+T+DP + + + G + DAP+SGG
Sbjct: 96 VVNAAQTETILFGADGVAQTLADGAVFLSSATMDPEIARTLAARLEATGRLYLDAPISGG 155
Query: 478 VMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQI-GSGQVAKLTNNMLMGITGM 654
A L +A G F ++ P L M AK + G G G K+ N +L G+
Sbjct: 156 AQRAAEGALTILASGSPAAFAKARPALDAMAAKLYELGDAPGQGAAFKMINQLLAGVHIA 215
Query: 655 ATAECM 672
A +E +
Sbjct: 216 AASEAV 221
>UniRef50_A1ZWM5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Microscilla marina ATCC 23134|Rep: 3-hydroxyisobutyrate
dehydrogenase - Microscilla marina ATCC 23134
Length = 295
Score = 92.7 bits (220), Expect = 8e-18
Identities = 61/193 (31%), Positives = 91/193 (47%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+AF+GLG MG MA+NL+K + Y+ S A G A++ S
Sbjct: 3 IAFIGLGIMGSRMASNLLKHKVDLTVYNRSLAATTPLVALGAKVAHTTTEAVKEADIVFS 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L S +VV V G+ G ++ K +L ID STI P A + + F +APV+G
Sbjct: 63 MLASPQVVKAVAYGQTGFLSKMKSKALWIDCSTISPAFALASAQEASKHEVVFVEAPVAG 122
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
A+NA L F+ GG ++ P +++MG K H G I K+ N L+ +
Sbjct: 123 TKSHAENAELVFLVGGGTTAIAQATPYMEMMGKKVVHIGAISKASALKILINYLLAQGML 182
Query: 655 ATAECMNMGH*NG 693
A AE + +G G
Sbjct: 183 AFAEALVVGEKQG 195
>UniRef50_Q8TT25 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Methanosarcina|Rep: 3-hydroxyisobutyrate dehydrogenase -
Methanosarcina acetivorans
Length = 300
Score = 92.7 bits (220), Expect = 8e-18
Identities = 60/195 (30%), Positives = 91/195 (46%), Gaps = 2/195 (1%)
Frame = +1
Query: 94 SSNTDKN--VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXX 267
+S DKN V +GLG MG A+NL+ +G+ V Y+ +K+ + G T ++
Sbjct: 3 TSGCDKNITVGVIGLGIMGSSFASNLLSRGYNVHVYNRTKEKAQPLIERGATFHSTPREL 62
Query: 268 XXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGL 447
+ LT V V G+DG++ AKKG L ID STIDP+ + A + GL
Sbjct: 63 ASVADIIMTSLTDEAAVNSVAFGEDGLLNGAKKGCLWIDLSTIDPSSSVKHAEAAKKAGL 122
Query: 448 GFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTN 627
D PV G A L + GG +E + L +G + G G+G KL
Sbjct: 123 ERLDTPVVGSKDLASKGELIILVGGSQEVLRKHEKFLNKLGKSVIYLGADGNGHKMKLAI 182
Query: 628 NMLMGITGMATAECM 672
N+ +G+ + +E +
Sbjct: 183 NLHLGLLAESFSEAL 197
>UniRef50_A0QUD5 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=1; Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 326
Score = 92.3 bits (219), Expect = 1e-17
Identities = 56/180 (31%), Positives = 91/180 (50%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+ V FLGLGNMG MA LV G + Y+ + A G A S+
Sbjct: 11 QRVGFLGLGNMGRPMARRLVASGTPLTVYNRTAAKCAEFADLGCEVAESVARMGHCSVLL 70
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
+ T + V VYLG DG+VA+A+ G++L+D STI P++ ++ G+ F APV
Sbjct: 71 TMLGTDDDVA-QVYLGDDGLVANARAGAVLVDCSTISPDMSARVRARCDRAGVHFLAAPV 129
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
+GG ++ LA G ++ FE + +L+V+ + G + ++ K+ +N+L+ T
Sbjct: 130 AGGPPVIESGGLAMAVSGDRQAFEHAADVLRVVAPNLIYVGPGDTSRLVKICHNLLVAAT 189
>UniRef50_Q6C351 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 334
Score = 91.5 bits (217), Expect = 2e-17
Identities = 71/217 (32%), Positives = 101/217 (46%), Gaps = 17/217 (7%)
Frame = +1
Query: 79 ARRAYSSNTDKNVAFLGLGNMGGFMAANLVKK------GFTVRGYDPSKDALNAAAKNG- 237
A R ++ D + F+GLG MG MA NL KK V +D +K AL AK+
Sbjct: 12 ALRPLRASRDLSYGFIGLGRMGLPMALNLQKKLPGVDADSKVNVFDMNKAALEQIAKDKD 71
Query: 238 -----VTPANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDP 402
+ S ++L V VY + K + +D STID
Sbjct: 72 PKGAQLEVLGSAVDVASKSDVIFTMLPEPVHVRGVYTDLVNNLGD-KTSKIFVDCSTIDT 130
Query: 403 NVPKQIFPIALEK--GLGFTDAPVSGGVMGAQNATLAFMAGGRKED---FERSLPLLKVM 567
+ + +K F DAPVSGGV+GA+ TL FM G K+ +++ LLK+M
Sbjct: 131 QTSIECGKLVTDKDASAAFVDAPVSGGVVGAEKGTLTFMVGCNKDKQQVYKQVEELLKLM 190
Query: 568 GAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNM 678
G + +CG G G AKL NN L+ +T +ATAE ++
Sbjct: 191 GGRIVNCGTQGQGLAAKLANNYLLAVTNVATAEAFHL 227
>UniRef50_Q1N6I0 Cluster: Putative oxidoreductase protein; n=1;
Oceanobacter sp. RED65|Rep: Putative oxidoreductase
protein - Oceanobacter sp. RED65
Length = 289
Score = 91.1 bits (216), Expect = 2e-17
Identities = 60/200 (30%), Positives = 97/200 (48%), Gaps = 2/200 (1%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKN--GVTPANSIXXXXXXXXX 285
N++F+GLG MG MA +LV+ + ++ S +N T ANS+
Sbjct: 2 NISFIGLGKMGYPMAKHLVQANHQLEVFNRSPSKSEDFKRNFEQCTIANSLTDCGKHSEI 61
Query: 286 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 465
+ +++ V + GKD + ++ K G+L+ID +T + ++ LEK + + DAP
Sbjct: 62 IILCIGNDEDVRNTLTGKDSLYSNLKPGTLVIDHTTTSAELACEMQAKLLEKQVDYVDAP 121
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 645
VSGG GA + L M GG+ ER+ + + H G IGSGQ+ K+ N + +
Sbjct: 122 VSGGEQGAISGQLTIMCGGQALAAERAQGITQAYSKSFTHMGPIGSGQLTKMVNQICVAG 181
Query: 646 TGMATAECMNMGH*NGTRTE 705
A AE ++ G G E
Sbjct: 182 LIEALAEGIHFGQQAGLDME 201
>UniRef50_A0NRG5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein; n=1; Stappia aggregata IAM
12614|Rep: 6-phosphogluconate dehydrogenase, NAD-binding
protein - Stappia aggregata IAM 12614
Length = 291
Score = 91.1 bits (216), Expect = 2e-17
Identities = 58/189 (30%), Positives = 87/189 (46%), Gaps = 1/189 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKD-ALNAAAKNGVTPANSIXXXXXXXXXXX 291
V F GLG MG MAANL G V ++ + + A A+ + PA +
Sbjct: 3 VGFAGLGRMGVRMAANLAAAGLEVSIWNRTAETARTFASAHNAFPAATPKDLAERSDIVI 62
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
++L + VY G DG+ + +L++ T+ + +++ A EKG F DAPVS
Sbjct: 63 TMLADDAAAETVYFGPDGLFEASSGAQVLVEMGTLSVPMAERLARAAQEKGRRFVDAPVS 122
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
G A++A L MAG D L V+G K G+ G+G KL NML+
Sbjct: 123 GATQAAKDAKLLIMAGATASDAPELAALFDVLGRKTIWLGKAGAGAAMKLGVNMLIHGLN 182
Query: 652 MATAECMNM 678
AE +++
Sbjct: 183 QTLAEALSL 191
>UniRef50_A0G5F9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phymatum
STM815
Length = 307
Score = 90.6 bits (215), Expect = 3e-17
Identities = 65/203 (32%), Positives = 93/203 (45%), Gaps = 1/203 (0%)
Frame = +1
Query: 76 AARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 255
++ +A S + F+G+G MG MA L++ G + +D + A+ G A S
Sbjct: 2 SSSQASSQQRGPLLGFVGVGTMGRPMARRLIEAGHALVVFDRDEAAVAELKAIGAQAAAS 61
Query: 256 IXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIAL 435
+ + L + + V LG DG + +L+D ST+ V K++ L
Sbjct: 62 VREIADSARIVFTSLPTPAIFRQVALG-DGGLIEGSAIKVLVDLSTVGSRVEKEVAQGLL 120
Query: 436 EKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQV 612
KG+ DAPVSGG GA+ TLA MA G E L V+G K F G + G GQ+
Sbjct: 121 AKGVETVDAPVSGGAAGAKKGTLAIMAAGSPVALEEVRGLFDVLG-KAFVVGDKAGQGQL 179
Query: 613 AKLTNNMLMGITGMATAECMNMG 681
KL NNML T+E G
Sbjct: 180 LKLLNNMLSSTAFAITSEAFVAG 202
>UniRef50_Q2UHA9 Cluster: Predicted dehydrogenase; n=16;
Pezizomycotina|Rep: Predicted dehydrogenase -
Aspergillus oryzae
Length = 363
Score = 90.6 bits (215), Expect = 3e-17
Identities = 77/227 (33%), Positives = 112/227 (49%), Gaps = 26/227 (11%)
Frame = +1
Query: 79 ARRAYSSNT--DKNVAFLGLGNMGGFMAANL--------------VKKGFTVRGYDPSKD 210
A RA+SS+ D F+GLG MG MA NL + + R + +++
Sbjct: 30 ATRAFSSSLRRDDTWGFIGLGQMGYAMAKNLRAKIPASDTLIIRDINENTAKRFVEETQE 89
Query: 211 AL-NAAAKNGVTPANSIXXXXXXXXXXXSILTS---NKVVLDVY--LGKDGVVAHAKKGS 372
A+ N+ AK + I+TS + V +V+ + + G + +K
Sbjct: 90 AVRNSGAKEDTSKVLIAQNAREVAEQSTVIVTSLPEPEHVKNVFYCMLRHGELPALEKER 149
Query: 373 LLIDSSTIDPNVPKQIFPIALEKGLG-FTDAPVSGGVMGAQNATLAFMAGGRKEDFE--- 540
L ID+STIDP ++I G F DAP+SGGV+GA+ TL+FM G + E
Sbjct: 150 LFIDTSTIDPASSREIANAIHTTRQGRFVDAPMSGGVVGARAGTLSFMFGASSQTGELVD 209
Query: 541 RSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMG 681
R +L +MG K +H G G+G AKL NN L+ I +ATAE MN+G
Sbjct: 210 RVQSVLMLMGKKAWHMGNSGTGVSAKLANNYLLAINNIATAEVMNLG 256
>UniRef50_A1UJF2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=6; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Mycobacterium sp. (strain KMS)
Length = 272
Score = 90.2 bits (214), Expect = 4e-17
Identities = 52/174 (29%), Positives = 81/174 (46%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V F+GLG+ GG MA +V+ G+ + + +L A A S
Sbjct: 3 VGFIGLGSQGGPMARRIVEGGYELTLWARRPASLEPYADTAAKTAGSPAELAAASDLVCV 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+ + V +V G GV+A G+++ ST+ P+ ++I A + + DAPVSG
Sbjct: 63 CVVGDDDVREVLYGDTGVLAGLAPGAMIAIHSTVHPDTCREIAEKAAAQNVSVIDAPVSG 122
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 636
G + L M GG + D E++ P+ H G +GSGQV K+ NN+L
Sbjct: 123 GAPAVEQGKLLVMVGGEEADVEKARPVFATYADPIVHLGPLGSGQVTKILNNLL 176
>UniRef50_Q13LQ9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=11;
Proteobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Burkholderia xenovorans (strain LB400)
Length = 296
Score = 89.8 bits (213), Expect = 6e-17
Identities = 64/196 (32%), Positives = 92/196 (46%), Gaps = 6/196 (3%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNA---AAKNGVTPANSIXXXXXXX 279
K V F+GLG MG M L K GF + + DA A A ++G N+
Sbjct: 5 KRVGFIGLGMMGAPMVQCLRKAGFEL--FIDDADAARADTLAEQSGSHRLNA--DNAGSL 60
Query: 280 XXXXSILTSNKVVLDVYLG---KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG 450
++L ++ +V V LG G A KG+++ID S+ +P + + + L
Sbjct: 61 DALITMLPNSAIVEAVVLGDGNNTGWAARLAKGAVVIDMSSSEPERSRALGKTLEAQRLA 120
Query: 451 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNN 630
+ DAPVSGGV A+ TLA + GG + R PLL MG H G G+G AK NN
Sbjct: 121 YLDAPVSGGVKRAKEGTLAILVGGHADVLARCKPLLDAMGTNVLHIGTAGAGHAAKALNN 180
Query: 631 MLMGITGMATAECMNM 678
+ + AT E + +
Sbjct: 181 YVSAASVAATVEALQI 196
>UniRef50_A0R1N4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 272
Score = 89.4 bits (212), Expect = 8e-17
Identities = 56/189 (29%), Positives = 85/189 (44%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V F+GLG+ G MA +V+ GF + +L A A +
Sbjct: 3 VGFIGLGSQGAPMARRIVEGGFETTLWARRPASLEPFADTAAKVAGTPAELAAASDLVCL 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+ + V +V G+ GV+A G ++ ST+ P+ +I EKG+ DAPVSG
Sbjct: 63 CVVGDDDVREVLDGETGVLAGLAPGGIIAIHSTVHPDTCTEIAEQVAEKGISLIDAPVSG 122
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G A+ TL MAGG ++ ++ P+ G +GSGQVAK+ NN+L
Sbjct: 123 GEPAAKAGTLLVMAGGDEDIVDKVRPVFATYADPVVRLGGVGSGQVAKILNNLLFSANLG 182
Query: 655 ATAECMNMG 681
A + +G
Sbjct: 183 AAMSALELG 191
>UniRef50_A0GPK7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Burkholderia|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 297
Score = 89.4 bits (212), Expect = 8e-17
Identities = 68/204 (33%), Positives = 91/204 (44%), Gaps = 4/204 (1%)
Frame = +1
Query: 103 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKD---ALNAAAKNGVTPANSIXXXXX 273
T + F GLG MG MA L G +R ++ S + AL A+A N V S
Sbjct: 2 TSARLGFCGLGKMGWPMAQRLADAGHALRVWNRSNEKAAALQASATNCVA-CESPAQVAA 60
Query: 274 XXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEK-GLG 450
L V V G DG+ A++G+ L+D ST+ P+ + E+ G
Sbjct: 61 GAGIVMLCLADAAAVEAVAFGVDGLANRARRGATLVDHSTLAPSQTRAFARRWREQTGGD 120
Query: 451 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNN 630
+ DAPVSGG GA TLA MAGG E P+L+ A+ G G+GQ KL N
Sbjct: 121 WIDAPVSGGTSGAAAGTLAIMAGGDATLIETLTPILRGYAARVTRMGGSGAGQATKLANQ 180
Query: 631 MLMGITGMATAECMNMGH*NGTRT 702
++ T A AE + G T
Sbjct: 181 TIVMTTIAALAEATRLARHAGIDT 204
>UniRef50_Q830A7 Cluster: 2-hydroxy-3-oxopropionate reductase; n=7;
Firmicutes|Rep: 2-hydroxy-3-oxopropionate reductase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 296
Score = 89.0 bits (211), Expect = 1e-16
Identities = 53/197 (26%), Positives = 88/197 (44%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+G G MG + N++K +V Y+ +K + G ++ +
Sbjct: 4 IGFIGTGVMGKSIIRNMMKNNLSVNVYNRTKSKTDDLVAEGAVWYDTPKAIAEASDIIFT 63
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
++ V VY + G+ G +++D +T P + ++I A E G DAPVSG
Sbjct: 64 MVGFPSDVEGVYFNETGIFQADLTGKIVVDLTTSTPTLAEKIAKKAAEVGAHALDAPVSG 123
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G +GA+N TL M GG +E ++ LP+ K G G G GQ K+ N +++ T
Sbjct: 124 GDLGAKNGTLTIMVGGDQESYDTVLPIFKTFGKTFMLHGSAGKGQHTKMANQLMIAGTMT 183
Query: 655 ATAECMNMGH*NGTRTE 705
E + + G E
Sbjct: 184 GLTEMLVYANATGLTLE 200
>UniRef50_A5FTT0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Alphaproteobacteria|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Acidiphilium cryptum (strain JF-5)
Length = 305
Score = 89.0 bits (211), Expect = 1e-16
Identities = 62/177 (35%), Positives = 87/177 (49%), Gaps = 1/177 (0%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKN-GVTPANSIXXXXXXXXX 285
+ VAF+GLGNMG MAA LV G V G D + A A+ G T A
Sbjct: 3 QRVAFIGLGNMGWPMAARLVGGGCEVTGCDAVEGRAEAFAREVGGTAAADADAAARGAEF 62
Query: 286 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 465
++L ++ +V V + G+LLI+ S+ P V ++I + DAP
Sbjct: 63 IVTMLPNSALVESVVAAMRPSLG---AGALLIEMSSGIPGVTRRIAAGLEAAKVAMIDAP 119
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 636
VSGGV A+ L+ M GG +D R+ LL++MG H G IG+GQ K NN++
Sbjct: 120 VSGGVARAKTGDLSIMTGGSADDCARAETLLRLMGTTITHVGDIGAGQAMKALNNLV 176
>UniRef50_Q49A26 Cluster: Cytokine-like nuclear factor n-pac; n=46;
Euteleostomi|Rep: Cytokine-like nuclear factor n-pac -
Homo sapiens (Human)
Length = 553
Score = 89.0 bits (211), Expect = 1e-16
Identities = 54/213 (25%), Positives = 94/213 (44%)
Frame = +1
Query: 55 STQCLYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKN 234
S Q + A + TDK + FLGLG MG + +NL+K G TV ++ + + + +
Sbjct: 250 SIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQE 309
Query: 235 GVTPANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPK 414
G + + ++ K D+ LG GV+ + G +D ST+D +
Sbjct: 310 GARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVT 369
Query: 415 QIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ 594
++ + + +G F +APVSG + + L +A G + +E + MG F G+
Sbjct: 370 ELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQTMGKTSFFLGE 429
Query: 595 IGSGQVAKLTNNMLMGITGMATAECMNMGH*NG 693
+G+ L NM+ G AE + + G
Sbjct: 430 VGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTG 462
>UniRef50_Q98I20 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 305
Score = 88.6 bits (210), Expect = 1e-16
Identities = 57/195 (29%), Positives = 92/195 (47%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
++ AF+GLG++GG +A +L++ GF + +D A+ G T ANS
Sbjct: 3 ESYAFIGLGHLGGNLAPSLIRNGFAITVFDRDPAAVERLVTLGATAANSPAEAAARAGNA 62
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
+ L S K+ V G G++ KG I+ ST + ++ +A +G+ + PV
Sbjct: 63 ITCLPSPKISEAVLAGPGGLLEGLPKGGTWIEMSTNGRDEIMRLAALASAEGVETLECPV 122
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
+GGV A + + GG +ER ++ M A+ F G IGS V K+ NML I
Sbjct: 123 TGGVHLAAVGKITALVGGDAALYERHRAAIEAMCARSFLMGPIGSAAVIKVITNMLAFIH 182
Query: 649 GMATAECMNMGH*NG 693
+A E + + G
Sbjct: 183 LVAAGEALMLAKQGG 197
>UniRef50_Q73P00 Cluster: 3-hydroxyacid dehydrogenase family
protein; n=4; Bacteria|Rep: 3-hydroxyacid dehydrogenase
family protein - Treponema denticola
Length = 292
Score = 88.6 bits (210), Expect = 1e-16
Identities = 56/187 (29%), Positives = 87/187 (46%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
+V F+GLG MG MA L G + + +K + G +
Sbjct: 7 DVGFIGLGVMGKSMAERLRAAGAKMHVFTRTKKSAEEILSKGAIWYDDPASLAPNCKIIF 66
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
+I+ + V + Y G+ G++ AK G++ D +T P + K+I+ A +K DAPVS
Sbjct: 67 TIVGYPQDVEETYFGEKGLLKTAKPGTIFADMTTSSPILAKKIYDEAKKKECFSVDAPVS 126
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
GG +GA+N TL+ MAGG + F+ P MG G G+GQ K+ N + +
Sbjct: 127 GGDIGAKNGTLSIMAGGDESAFKELEPFFACMGKTWALQGGAGAGQHTKMANQIAVAANL 186
Query: 652 MATAECM 672
T E +
Sbjct: 187 FGTVEAV 193
>UniRef50_Q0FFH2 Cluster: Putative 2-hydroxyacid dehydrogenase; n=2;
Alphaproteobacteria|Rep: Putative 2-hydroxyacid
dehydrogenase - alpha proteobacterium HTCC2255
Length = 303
Score = 88.6 bits (210), Expect = 1e-16
Identities = 52/188 (27%), Positives = 90/188 (47%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLG MGG + NL++ G + D + G A++ +
Sbjct: 3 IGFIGLGTMGGAASLNLIRGGHQLTVCDLDLKRATKHLELGAKWADTPSEAAKDVDIVFT 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
++ K + + G++G++ G + +D +T P + +++ ++ G DAPV+G
Sbjct: 63 MVFGPKQIEQIIRGENGLLHSMGPGQVWVDLTTNQPELARELAQEIIDTGAIAIDAPVTG 122
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
V GA+N + AGG KE ER P++++MG + G GSG + KL +N L I
Sbjct: 123 AVDGARNGNMTQFAGGDKETIERIRPVMELMGPVHY-MGSNGSGSITKLASNQLWAIHAT 181
Query: 655 ATAECMNM 678
A E + M
Sbjct: 182 AMGEALVM 189
>UniRef50_A4SWE8 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=7; Proteobacteria|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 299
Score = 88.2 bits (209), Expect = 2e-16
Identities = 59/189 (31%), Positives = 90/189 (47%), Gaps = 3/189 (1%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSK---DALNAAAKNGVTPANSIXXXXXXXXX 285
+ F+GLG MG MA++L+ G + SK + N+AA TPA
Sbjct: 6 LGFIGLGIMGAPMASHLMAAGHALFINTRSKVPEELANSAAVVCATPAE----VAKMADI 61
Query: 286 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 465
+++ V V G+ GV KG +++D S+I P K G + DAP
Sbjct: 62 IFTMVPDTPDVEKVLFGEHGVAHGLSKGKIVVDMSSISPIATKDFAKKINALGCEYLDAP 121
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 645
VSGG +GA+ TL M GG++ F+ P+ +MG G G+GQV K+ N +++ +
Sbjct: 122 VSGGQVGAKGGTLTIMVGGKESVFQTVKPMFDLMGKNITLVGDNGAGQVTKVANQIIVAL 181
Query: 646 TGMATAECM 672
A AE +
Sbjct: 182 NIEAVAEAL 190
>UniRef50_A7DSF1 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
2-hydroxy-3-oxopropionate reductase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 292
Score = 88.2 bits (209), Expect = 2e-16
Identities = 54/186 (29%), Positives = 85/186 (45%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
K + +GLG +G + +L++ GF V ++ SKD A + G T +S
Sbjct: 2 KKIGIVGLGMLGNAVGLHLLESGFEVTVFNRSKDKTIQAKEKGATVVDSPKEVAEKSDLV 61
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
++ V +V ++G++ K ++ D STIDP+ K I LE G+ D PV
Sbjct: 62 IIVVKDADAVKEVSFEREGIIKSENKKLIVADMSTIDPSESKNISDKFLEFGIHKLDIPV 121
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
GG A L MA G KE FE + + + K F G+ G KL N+ + +
Sbjct: 122 MGGPNVAITGDLVMMASGNKESFEECKKVFEKIANKVFFLGEKGVAHSIKLAMNLQITML 181
Query: 649 GMATAE 666
+A +E
Sbjct: 182 ALALSE 187
>UniRef50_Q89M84 Cluster: Blr4309 protein; n=6;
Bradyrhizobiaceae|Rep: Blr4309 protein - Bradyrhizobium
japonicum
Length = 293
Score = 87.8 bits (208), Expect = 2e-16
Identities = 57/184 (30%), Positives = 86/184 (46%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
VAF+GLG MG MA + GFTV ++ SK G A S +
Sbjct: 4 VAFIGLGRMGHGMAGRYLDAGFTVTLWNRSKTKAEDLIARGAHWATSPEDAAIDADAVVT 63
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
++ ++ V+LG G AK G++ I+ ST+ + +++ +GL + D PV+G
Sbjct: 64 MVADDEASRAVWLGPKGAAKTAKAGTIAIECSTVSYDHAREMGRELNARGLIYIDCPVTG 123
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
A L + G D ER+ P L+ +G+ H G +GSG V KL NN++ I
Sbjct: 124 LPDAAAAGKLTLLVGADAADLERARPYLEPIGSTIRHFGAVGSGTVYKLINNLMGAIQIA 183
Query: 655 ATAE 666
AE
Sbjct: 184 GLAE 187
>UniRef50_Q1B326 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding protein precursor; n=7; Bacteria|Rep:
6-phosphogluconate dehydrogenase, NAD-binding protein
precursor - Mycobacterium sp. (strain MCS)
Length = 299
Score = 87.8 bits (208), Expect = 2e-16
Identities = 55/191 (28%), Positives = 93/191 (48%), Gaps = 1/191 (0%)
Frame = +1
Query: 103 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXX 282
++ ++ F+GLGNMG MAANL+ G V Y+ S D ++A + G PA ++
Sbjct: 2 SNMHIGFIGLGNMGSAMAANLLAAGHDVTAYNRSPDKVDALSAEGARPARTV-AEACQGD 60
Query: 283 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 462
++L ++ V V G DG+VA + ++ + SSTI + +++ E G F A
Sbjct: 61 VVVTMLANDDAVEAVSFGDDGIVASLRPDAIHVSSSTISLALAERLTAAHAEGGSRFVSA 120
Query: 463 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLM 639
PV G A A L +A G + E P+ + +G + F G + + + K++ N L+
Sbjct: 121 PVFGRPEAAAAAKLFVVAAGAPDTVEALAPVFEAIGQRTFVVGTEPKAANLVKVSGNFLI 180
Query: 640 GITGMATAECM 672
+ E M
Sbjct: 181 ASVIESLGEAM 191
>UniRef50_Q4WV01 Cluster: Oxidoreductase, acting on the CH-OH group
of donors, NAD or NADP as acceptor; n=7;
Pezizomycotina|Rep: Oxidoreductase, acting on the CH-OH
group of donors, NAD or NADP as acceptor - Aspergillus
fumigatus (Sartorya fumigata)
Length = 435
Score = 87.8 bits (208), Expect = 2e-16
Identities = 58/192 (30%), Positives = 90/192 (46%), Gaps = 6/192 (3%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLG MG MA NLV++G+ V G+D ++ G PA+S+
Sbjct: 6 IGFVGLGAMGFGMATNLVREGYPVVGFDVFPASVQRFQSQGGIPASSLRESAEGKDFYIC 65
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG---LGFTDAP 465
++ S V V G DGVV K + L ST+ + + + +G + F D P
Sbjct: 66 MVASAPQVQSVLFGDDGVVQFLPKNATLFLCSTVPASYAQSVAAELQSRGRADIRFIDCP 125
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQ---FHCGQIGSGQVAKLTNNML 636
VSGG A + TL+ MAG +E +L+VM + G +G+G K+ + +L
Sbjct: 126 VSGGAKRAADGTLSIMAGASEEALNSGREILQVMSDQNKLYLVPGGVGAGSNMKMVHQVL 185
Query: 637 MGITGMATAECM 672
GI + +E M
Sbjct: 186 AGIHILGASEAM 197
>UniRef50_Q7NR40 Cluster: Probable 3-hydroxyisobutyrate
dehydrogenase; n=1; Chromobacterium violaceum|Rep:
Probable 3-hydroxyisobutyrate dehydrogenase -
Chromobacterium violaceum
Length = 296
Score = 87.4 bits (207), Expect = 3e-16
Identities = 56/195 (28%), Positives = 90/195 (46%), Gaps = 4/195 (2%)
Frame = +1
Query: 100 NTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDAL----NAAAKNGVTPANSIXXX 267
N K +A +G G MG + L+ G+ VR Y+ S + +A A TPA ++
Sbjct: 5 NAGKRLALIGCGAMGTALGLRLLGLGWEVRVYNRSPERTAPLRDAGASAHATPAEAVAGA 64
Query: 268 XXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGL 447
++LT + + + G +G+ + G L+D T P + A G
Sbjct: 65 DWVA----TVLTDSAALRALLFGDNGIASAPAAGRRLVDLGTHQPTQLAALGAEAAAAGW 120
Query: 448 GFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTN 627
+AP++G V A + TL F+ GG + D E + PLL +G H G +G+G AKL
Sbjct: 121 PLVEAPMTGSVHDASHGTLHFLVGGAEADVEWASPLLWALGRGVHHLGGLGAGNTAKLAL 180
Query: 628 NMLMGITGMATAECM 672
N+L+G+ E +
Sbjct: 181 NLLVGVMAGGLGEAI 195
>UniRef50_Q89RT2 Cluster: Bll2680 protein; n=1; Bradyrhizobium
japonicum|Rep: Bll2680 protein - Bradyrhizobium
japonicum
Length = 300
Score = 87.0 bits (206), Expect = 4e-16
Identities = 51/199 (25%), Positives = 89/199 (44%)
Frame = +1
Query: 97 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXX 276
++ +NVAF+G+G MG M+ + K G+ V +D S N A G++ A S
Sbjct: 2 TDASRNVAFIGIGKMGLPMSVLVAKAGYAVTAFDRSAARTNEARAQGISIAASPDDAVSG 61
Query: 277 XXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFT 456
+ L + + LG GV+A G++LI++ST+ ++ A +G+ +
Sbjct: 62 KEAVITSLPDDTALRGALLGPAGVIAAMAPGAVLIETSTVSVEASTEVAASAQARGVLYL 121
Query: 457 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 636
APVSG L G K+ F+ + PL + + G + AKL N++
Sbjct: 122 RAPVSGNASIVHTGALTCFVSGPKDAFDNAKPLFAAFTRARTYLGPAEEARYAKLAVNLM 181
Query: 637 MGITGMATAECMNMGH*NG 693
+ ++ AE + + G
Sbjct: 182 IAVSAAMMAESLALARKGG 200
>UniRef50_Q3W9L4 Cluster: Putative uncharacterized protein; n=1;
Frankia sp. EAN1pec|Rep: Putative uncharacterized
protein - Frankia sp. EAN1pec
Length = 294
Score = 87.0 bits (206), Expect = 4e-16
Identities = 56/175 (32%), Positives = 84/175 (48%), Gaps = 1/175 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V F+GLG+ GG MA + +G+ + + ++ A + GV S
Sbjct: 18 VGFIGLGSQGGPMARRIADEGYPLTIW--ARRAASVEPLAGVAAVASTPAEVGESSDVVG 75
Query: 295 I-LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
I + ++ V DV L DGV+A G +++ STI P +++ A ++ + DAPVS
Sbjct: 76 ICVVADADVEDVLLRADGVLAGMAAGGVVVIHSTIRPETCQRLATEAAKQEISIIDAPVS 135
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 636
GG A L M GG + R P+L+ H G +GSGQVAKL NN +
Sbjct: 136 GGGDAAAQRRLLVMVGGEDDAVARCRPVLETFACPVIHLGPLGSGQVAKLVNNFV 190
>UniRef50_P77161 Cluster: 2-hydroxy-3-oxopropionate reductase; n=99;
Proteobacteria|Rep: 2-hydroxy-3-oxopropionate reductase
- Escherichia coli (strain K12)
Length = 292
Score = 87.0 bits (206), Expect = 4e-16
Identities = 58/188 (30%), Positives = 88/188 (46%), Gaps = 2/188 (1%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFT--VRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+ F+GLG MG MA NL + G V P D L + V A +
Sbjct: 3 LGFIGLGIMGTPMAINLARAGHQLHVTTIGPVADELLSLGAVSVETARQVTEASDIIFI- 61
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
++ V +V G++G + KG ++D S+I P K+ E G + DAPV
Sbjct: 62 --MVPDTPQVEEVLFGENGCTKASLKGKTIVDMSSISPIETKRFARQVNELGGDYLDAPV 119
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SGG +GA+ TL+ M GG + FER PL +++G G G GQ K+ N +++ +
Sbjct: 120 SGGEIGAREGTLSIMVGGDEAVFERVKPLFELLGKNITLVGGNGDGQTCKVANQIIVALN 179
Query: 649 GMATAECM 672
A +E +
Sbjct: 180 IEAVSEAL 187
>UniRef50_Q13PY3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Burkholderia xenovorans (strain LB400)
Length = 302
Score = 86.6 bits (205), Expect = 5e-16
Identities = 58/190 (30%), Positives = 84/190 (44%), Gaps = 1/190 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ +GLGN+G A L+ G + YD +A+ G A
Sbjct: 3 IGLIGLGNIGQHFATRLLAAGHPLVVYDTRDEAMQRFGALGAELAKDTVDLASRAEVVFL 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
L VV +V G GV + +++D ST P+V I ++ + F APVSG
Sbjct: 63 SLPLPSVVEEVATGPHGV-SQGSSVRIVVDLSTTGPSVSNVIARKLADRHIQFLGAPVSG 121
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLMGITG 651
G + A+ TL MA G E FE P L+V+G F+ G G GQ K+ NN L +
Sbjct: 122 GTVAAEKGTLTVMAAGPMEAFETVEPWLRVIGKNIFYLGSGAGLGQTMKIINNTLCAVGM 181
Query: 652 MATAECMNMG 681
+A+ E + G
Sbjct: 182 VASCEALVFG 191
>UniRef50_A6F020 Cluster: Putative uncharacterized protein; n=1;
Marinobacter algicola DG893|Rep: Putative
uncharacterized protein - Marinobacter algicola DG893
Length = 286
Score = 86.6 bits (205), Expect = 5e-16
Identities = 55/188 (29%), Positives = 90/188 (47%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V+ +G+G+MG +A ++ KG V YD S++ + AKNG+ S+
Sbjct: 3 VSIIGVGDMGRDIAVHVRDKGHDVIAYDISEERRSDVAKNGIKVVESLAEAVAKAEVHLV 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
I+ +++ V ++ GS ++ +T P + + +KGLGF DAPV
Sbjct: 63 IVATDEQSETV---TREILESGPAGSTVVILATNSPKTMQVLAAECEDKGLGFVDAPVVF 119
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G GA+ L + GG + + P+L+ H G +GSGQVAK NNML +
Sbjct: 120 GRQGAKEGQLGSLCGGDDKQVAKITPVLESYSKAVHHVGPVGSGQVAKACNNMLHWAACV 179
Query: 655 ATAECMNM 678
A E +++
Sbjct: 180 ANFEVLSL 187
>UniRef50_A0LDJ3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Magnetococcus sp. MC-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Magnetococcus sp. (strain MC-1)
Length = 292
Score = 86.6 bits (205), Expect = 5e-16
Identities = 55/188 (29%), Positives = 85/188 (45%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+ + F+GLG MG MA + G+ + Y+ L + A +
Sbjct: 2 QKIGFIGLGIMGSAMANSCHHAGYQLCVYNRGHARLKPFIDRSIPTAATPQALATQSDYM 61
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
+++ +L+V G GV + G ++I++ST+ +Q + + G F DAPV
Sbjct: 62 VIMVSDPAALLEVLQGPVGVCSADLTGKVVINASTVSVEASQQAATLVEQVGGAFLDAPV 121
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SG + AQ L F+AGG +R PLL MG+ CG +G G KL N+LM
Sbjct: 122 SGSKIPAQTGKLVFLAGGHHAVIQRCEPLLLSMGSAVIPCGAVGDGTRMKLAMNLLMSGM 181
Query: 649 GMATAECM 672
A AE +
Sbjct: 182 VQALAESL 189
>UniRef50_A1CAY2 Cluster: Oxidoreductase, acting on the CH-OH group
of donors, NAD or NADP as acceptor; n=2;
Aspergillus|Rep: Oxidoreductase, acting on the CH-OH
group of donors, NAD or NADP as acceptor - Aspergillus
clavatus
Length = 436
Score = 86.6 bits (205), Expect = 5e-16
Identities = 59/192 (30%), Positives = 91/192 (47%), Gaps = 6/192 (3%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLG MG MA NLV++G+ V GYD ++ G PA+S+
Sbjct: 6 IGFVGLGAMGFGMATNLVREGYPVVGYDVFPASVQRFQTAGGIPASSLRESAEGKDFYVC 65
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG---LGFTDAP 465
++ S V V G DG+V + + L ST+ + + + G + F D P
Sbjct: 66 MVASAPQVQSVLFGDDGIVQYLPPNATLFLCSTVPASYAQSVAAELQSLGRADIRFIDCP 125
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMG-AKQFHC--GQIGSGQVAKLTNNML 636
VSGG A + TL+ MAG +E +L+VM K+ + G IG+G K+ + +L
Sbjct: 126 VSGGAKRAADGTLSIMAGAPEEALNSGREILQVMSDQKKLYLVPGGIGAGSNMKMVHQVL 185
Query: 637 MGITGMATAECM 672
GI + +E M
Sbjct: 186 AGIHILGASEAM 197
>UniRef50_Q9JYH6 Cluster: 3-hydroxyacid dehydrogenase; n=5;
Proteobacteria|Rep: 3-hydroxyacid dehydrogenase -
Neisseria meningitidis serogroup B
Length = 289
Score = 86.2 bits (204), Expect = 7e-16
Identities = 60/205 (29%), Positives = 90/205 (43%), Gaps = 1/205 (0%)
Frame = +1
Query: 94 SSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXX 273
S+N + ++GLG MG M L+ G V Y+ S D + G +
Sbjct: 2 SANEYAQIGWIGLGQMGLPMVTRLLDGGIEVGVYNRSPDKTAPISAKGAKVYGNTAELVR 61
Query: 274 XXXXXXSILTSNKVVLDVYLG-KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG 450
+++ V D+ G +DG+ G ++++ STI P + + G
Sbjct: 62 DYPVIFLMVSDYAAVCDILNGVRDGLA-----GKIIVNMSTISPTENLAVKALVEAAGGQ 116
Query: 451 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNN 630
F +APVSG V A N TL + GG + + ++G K FH G +G G AKL N
Sbjct: 117 FAEAPVSGSVGPATNGTLLILFGGSEAVLNPLQKIFSLVGKKTFHFGDVGKGSGAKLVLN 176
Query: 631 MLMGITGMATAECMNMGH*NGTRTE 705
L+GI G A +E M M G T+
Sbjct: 177 SLLGIFGEAYSEAMLMARQFGIDTD 201
>UniRef50_Q8VYC5 Cluster: Fructose-bisphosphate aldolase; n=12;
cellular organisms|Rep: Fructose-bisphosphate aldolase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 1373
Score = 86.2 bits (204), Expect = 7e-16
Identities = 66/200 (33%), Positives = 90/200 (45%), Gaps = 4/200 (2%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLG MG MAA+L+K F+V GYD K L G ANS
Sbjct: 324 IGFIGLGAMGFGMAAHLLKSNFSVCGYDVYKPTLVRFENAGGLAANSPAEVTKDVDVLVI 383
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALE---KGLGFTDAP 465
++T+ DV G G V G+ ++ +ST+ P Q+ LE K L DAP
Sbjct: 384 MVTNEVQAEDVLYGHLGAVEAIPSGATVVLASTVSPAFVSQL-ERRLENEGKDLKLVDAP 442
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNMLMG 642
VSGGV A L MA G E + + +L + K + G G+G K+ N +L G
Sbjct: 443 VSGGVKRAAMGELTIMASGTDEALKSAGLVLSALSEKLYVIKGGCGAGSGVKMVNQLLAG 502
Query: 643 ITGMATAECMNMGH*NGTRT 702
+ + AE M G G T
Sbjct: 503 VHIASAAEAMAFGARLGLNT 522
Score = 68.1 bits (159), Expect = 2e-10
Identities = 50/192 (26%), Positives = 91/192 (47%), Gaps = 3/192 (1%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V F+GL + +A++L++ GF V+ ++ S + + + G +S
Sbjct: 5 VGFVGLDSFSFELASSLLRSGFKVQAFEISTELVEKFIELGGHKCDSPADVGKAAAAVVV 64
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG--LGFTDAPV 468
+L+ + DV G +GV+ +K ++L+ SSTI +++ EK + DA V
Sbjct: 65 VLSHPDQIQDVIFGDEGVMKGLQKDAVLLLSSTISTLQLQKLEKQLTEKREQIFVVDAYV 124
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNMLMGI 645
G+ + L +A GR + R+ P L M + G+IG+G K+ N +L GI
Sbjct: 125 LKGMSELLDGKLMIIASGRSDSITRAQPYLTAMCQNLYTFEGEIGAGSKVKMVNELLEGI 184
Query: 646 TGMATAECMNMG 681
+A E +++G
Sbjct: 185 HLVAAVEAISLG 196
>UniRef50_O33730 Cluster: Uncharacterized oxidoreductase Sfri_1503;
n=167; Bacteria|Rep: Uncharacterized oxidoreductase
Sfri_1503 - Shewanella frigidimarina (strain NCIMB 400)
Length = 291
Score = 86.2 bits (204), Expect = 7e-16
Identities = 55/184 (29%), Positives = 91/184 (49%), Gaps = 3/184 (1%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPS-KDALNAAAKNGVTPANSIXXXXXXXXXXX 291
VAF+GLG MG MA +LVK+G V Y+ + A + G A++
Sbjct: 4 VAFIGLGVMGFPMAGHLVKQGHDVTVYNRTGAKATQWVEQYGGKKADTPKDAAQGQDIVF 63
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
+ + ++ + V LG+ G+V G++L+D +T +V ++I + F DAPVS
Sbjct: 64 TCVGNDDDLRQVVLGEHGIVHGMHAGAILVDHTTASADVAREIAAYIEPLNIAFLDAPVS 123
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG--I 645
GG GA+N L M GG + F+ P++ G +G+GQ+ K+ N + + +
Sbjct: 124 GGQAGAENGALTVMMGGDQAHFDTVKPVISAYSRCAELLGPVGAGQLTKMVNQICIAGVV 183
Query: 646 TGMA 657
G+A
Sbjct: 184 QGLA 187
>UniRef50_Q5LQR0 Cluster: 6-phosphogluconate dehydrogenase domain
protein; n=14; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase domain protein - Silicibacter pomeroyi
Length = 302
Score = 85.8 bits (203), Expect = 9e-16
Identities = 64/194 (32%), Positives = 90/194 (46%), Gaps = 4/194 (2%)
Frame = +1
Query: 97 SNTDK-NVAFLGLGNMGGFMAANLVKKGF--TVRGYDPSKDALNAAAKNGVTPANSIXXX 267
+N DK ++ F+GLG MG M L K G TV G + + + AA G T A
Sbjct: 4 NNMDKAHIGFIGLGLMGAAMVECLQKAGHAVTVLG-NRDRTGVEAALARGATEAAHARAV 62
Query: 268 XXXXXXXXSIL-TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG 444
+ TS +V +Y G DGV+A ++G ++ID T P ++I KG
Sbjct: 63 AEASDIVMLCMGTSAQVESRIY-GDDGVLAGTREGQVVIDFGTSLPASTRRIGGDLAGKG 121
Query: 445 LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLT 624
+ DAP+ A++ L M G K F+R P+L +G FH G +G+G KL
Sbjct: 122 ATYLDAPLGRTPAHARDGLLNIMCSGDKATFDRVKPVLHTLGENVFHLGALGNGHTIKLI 181
Query: 625 NNMLMGITGMATAE 666
NN T A AE
Sbjct: 182 NNCYSMTTACAMAE 195
>UniRef50_Q46TQ0 Cluster: UDP-glucose/GDP-mannose
dehydrogenase:Prephenate dehydrogenase:NADP
oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Ralstonia eutropha JMP134|Rep:
UDP-glucose/GDP-mannose dehydrogenase:Prephenate
dehydrogenase:NADP oxidoreductase, coenzyme
F420-dependent:6-phosphogluconate dehydrogenase,
NAD-binding - Ralstonia eutropha (strain JMP134)
(Alcaligenes eutrophus)
Length = 294
Score = 85.8 bits (203), Expect = 9e-16
Identities = 54/193 (27%), Positives = 88/193 (45%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+G G MG MA ++ G V YD + + +AA G+ A S+ S
Sbjct: 3 IGFIGTGKMGLPMARHIAAAGHDVVAYDIAPEQASAARHAGLAVAPSLADAVSAAEVIFS 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+ N G+ + A+ G+L ID+ST+ P + P+ + + + VSG
Sbjct: 63 SMP-NDGAFSAVAGQ--IAKAARPGALYIDTSTVSPAASAAVAPLLAARDIAYLRVTVSG 119
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
A+ A L + G + +ER PLL +G QF+ G ++ KL N+L+ +TG
Sbjct: 120 NNHMAEAAKLTALVSGPADAYERIKPLLAALGPAQFYLGDAEQARLMKLVVNLLIALTGG 179
Query: 655 ATAECMNMGH*NG 693
AE + +G G
Sbjct: 180 MLAEALTLGSKGG 192
>UniRef50_Q656T5 Cluster: Oxidoreductase-like; n=3; Oryza
sativa|Rep: Oxidoreductase-like - Oryza sativa subsp.
japonica (Rice)
Length = 341
Score = 85.8 bits (203), Expect = 9e-16
Identities = 58/201 (28%), Positives = 87/201 (43%)
Frame = +1
Query: 40 ARTILSTQCLYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALN 219
AR + S C +++ + V FLGLG MG MA+NL+ G V ++ ++ +
Sbjct: 30 ARLVFS--CSASSSSPSGEGGFSGKVGFLGLGIMGAPMASNLINAGCDVTVWNRTRSKCD 87
Query: 220 AAAKNGVTPANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTID 399
G S ++L + ++V G +G G +D ST+D
Sbjct: 88 PLLSLGAKYEPSPADVASSCDVTFAMLADPESAVEVACGANGAAQGMAPGKGYVDVSTVD 147
Query: 400 PNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQ 579
K I G F +APVSG A++ L F+ G + + R LL VMG +
Sbjct: 148 AATSKLIGKHITSTGASFLEAPVSGSKKPAEDGLLIFLTAGDESLYNRVASLLDVMGKSR 207
Query: 580 FHCGQIGSGQVAKLTNNMLMG 642
F G +G G KL NM+MG
Sbjct: 208 FFLGDVGKGADMKLVVNMVMG 228
>UniRef50_A1WJN2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Verminephrobacter eiseniae
(strain EF01-2)
Length = 297
Score = 85.4 bits (202), Expect = 1e-15
Identities = 58/190 (30%), Positives = 87/190 (45%), Gaps = 1/190 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKK-GFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
+ F+GLG MG + NL +K G V +D L A +GV S
Sbjct: 9 IGFIGLGVMGEPICRNLARKSGAQVLAFDLDAAPLQRLAADGVQGQGSASAVMAQSDTVF 68
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
L S +V + +DG++A A+ G +++D T + +Q+ + F DAPV+
Sbjct: 69 LSLPSGAIVAQLCRQQDGLLASARPGHIVVDLGTSSVDGTRQLAAEFAARQAKFADAPVA 128
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
AQ TLA M G E F PL+ + CG +G GQV K+ NNM++ T
Sbjct: 129 RTRAAAQAGTLAVMVGADPELFGVIEPLIATFASDIALCGPVGCGQVLKILNNMILFETV 188
Query: 652 MATAECMNMG 681
+A +E +G
Sbjct: 189 VAISEAKAIG 198
>UniRef50_Q121N3 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=19;
Burkholderiales|Rep: 3-hydroxyisobutyrate dehydrogenase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 298
Score = 85.0 bits (201), Expect = 2e-15
Identities = 53/191 (27%), Positives = 84/191 (43%), Gaps = 1/191 (0%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
NV +GLG MG +A L G+ V YD A+ G +++
Sbjct: 5 NVGVIGLGAMGRGIAQTLRSAGYAVHVYDVRAQAVQEFVAAGGVACDTLTQLAAACEVVV 64
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
S++ + DV + GV + K GS+ + ST+DP + G+ + DAP+S
Sbjct: 65 SVVVNAAQTEDVLWSEQGVASAMKSGSVFVMCSTVDPQWSIATEARLDKLGIHYVDAPIS 124
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLMGIT 648
GG A + M+ R +E++ +L M K + G G+G K+ N +L G+
Sbjct: 125 GGAAKAAAGQMTVMSSARPAAYEKAGDVLAAMAGKVYRLGDCAGAGSKVKIINQLLAGVH 184
Query: 649 GMATAECMNMG 681
A AE M +G
Sbjct: 185 IAAAAEAMALG 195
>UniRef50_A6G049 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-hydroxyisobutyrate
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 307
Score = 85.0 bits (201), Expect = 2e-15
Identities = 55/189 (29%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAK-----------NGVTPANSIX 261
+AFLG G MG M NL G +R Y+ +K AAA V +
Sbjct: 4 IAFLGTGTMGAGMVRNLAAAGHELRIYNRTKSRAEAAADVVADTVDLSSGGSVRVVDEPV 63
Query: 262 XXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEK 441
+ + S+ V LG+ G +A +G+L+ID T + +Q+ +
Sbjct: 64 YAARGAEFIIACVGSDAATFAVLLGEGGALAGVGQGALVIDCGTTSLKLTEQLAAACEGE 123
Query: 442 GLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAK 618
G F DAP++G +GA+ L M G +E R++PL ++MG H + +G GQ AK
Sbjct: 124 GASFLDAPITGSKLGAEGGKLTIMVAGEEEIVARAMPLFEIMGKHTVHVSERLGDGQRAK 183
Query: 619 LTNNMLMGI 645
NM +
Sbjct: 184 YCLNMTQAV 192
>UniRef50_Q3W3N3 Cluster: Putative uncharacterized protein; n=1;
Frankia sp. EAN1pec|Rep: Putative uncharacterized
protein - Frankia sp. EAN1pec
Length = 315
Score = 84.6 bits (200), Expect = 2e-15
Identities = 53/199 (26%), Positives = 86/199 (43%)
Frame = +1
Query: 76 AARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANS 255
AA + SS ++ F+GLG+ G + G + YD D G++ A +
Sbjct: 3 AAPQGDSSLANETYGFVGLGHQGSQIVRRCASAGRHLVVYDTQTDRAEQFRPAGMSVAGT 62
Query: 256 IXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIAL 435
+ + S++ V V G G++ + GSL++ ST P + A
Sbjct: 63 LAELGRRVTVASVCVYSDEDVRTVVAGPGGLLETMRSGSLVVIHSTCSPRTCVDLAARAR 122
Query: 436 EKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVA 615
+G+ DAPVS G L +AGG + D +R P+ ++ G + G +GS Q+
Sbjct: 123 GRGITVLDAPVSNGAPDESGRQLVVLAGGDRRDVDRCAPVFELFGRTVVYTGDVGSAQLT 182
Query: 616 KLTNNMLMGITGMATAECM 672
KL NN L + A E +
Sbjct: 183 KLVNNALFIVHRSAAIEAL 201
>UniRef50_Q2CHC8 Cluster: Oxidoreductase; n=1; Oceanicola granulosus
HTCC2516|Rep: Oxidoreductase - Oceanicola granulosus
HTCC2516
Length = 288
Score = 84.2 bits (199), Expect = 3e-15
Identities = 53/193 (27%), Positives = 87/193 (45%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V +GLG MG M L ++GF R ++ + + G +S
Sbjct: 3 VGVIGLGIMGAPMVRRLRERGFETRVWNLEPERFAQVSDAGALWCDSPAGVRAASDIVVL 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+ + V DV G G+ A A +++D ST+ P + I A + DAPVSG
Sbjct: 63 CVLDGRAVEDVCFGAQGL-AGAGGAEIVVDCSTVPPEATRDI---AGRMDAAWIDAPVSG 118
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G A+ L + GG++ D ER+ ++ + A H G +G+GQ AK N ++G+ +
Sbjct: 119 GPQLAETGELTMLLGGQERDIERARAVIDALAANATHLGPLGAGQAAKTLNQAIVGVNYV 178
Query: 655 ATAECMNMGH*NG 693
AE + + +G
Sbjct: 179 LMAELLALARKSG 191
>UniRef50_A2C1U6 Cluster: 3-hydroxyisobutyrate dehydrogenase and
related beta-hydroxyacid dehydrogenases; n=2;
Prochlorococcus marinus|Rep: 3-hydroxyisobutyrate
dehydrogenase and related beta-hydroxyacid
dehydrogenases - Prochlorococcus marinus (strain NATL1A)
Length = 287
Score = 84.2 bits (199), Expect = 3e-15
Identities = 55/189 (29%), Positives = 87/189 (46%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+AF+GLG +G M+ L+ G+ + Y +K ++ K P ++
Sbjct: 3 LAFIGLGAIGKPMSQRLIDNGYDLNLYQRNKLNNDSKRKYFFDPIEAVSDCDGLLIC--- 59
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+T + V V G +GV K S +ID STI P+ I E+ + + D PVSG
Sbjct: 60 -VTDDNAVESVLFGDNGVSGSLKPNSFVIDFSTISPDKSISIHKRLGEQNIFYVDCPVSG 118
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G GA N +L+ G ++D + +V+G + +G GQ K N +L+ T
Sbjct: 119 GTEGAHNGSLSLFIGASEKDCLSFENIFQVLGKSINYFNGVGKGQQVKALNQILVAGTYA 178
Query: 655 ATAECMNMG 681
A AE M +G
Sbjct: 179 AVAEAMELG 187
>UniRef50_Q6UCZ9 Cluster: Predicted oxidoreductase; n=2;
environmental samples|Rep: Predicted oxidoreductase -
uncultured marine proteobacterium ANT32C12
Length = 309
Score = 83.8 bits (198), Expect = 4e-15
Identities = 54/197 (27%), Positives = 94/197 (47%), Gaps = 1/197 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLG MG MA +L K+ + ++ S++ + A +
Sbjct: 23 IGFIGLGVMGYPMAGHLSKEFSNICIFNRSQEKVTKWLNQYSGTAFDTPEELSSQCNVIA 82
Query: 295 ILTS-NKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
+ ++ V ++ GK G++ G+++ID +T + K++ +AL+K + F DAP+S
Sbjct: 83 LCVGRDEDVREMMSGKKGILNSVNPGTIIIDHTTTSATLSKEMNELALQKDVIFLDAPIS 142
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
GG GA++ L+ M GG K +E P+L + G GSGQ+ K+ N + +
Sbjct: 143 GGQAGAESGQLSVMVGGDKASYESVKPILDNYSKFTKYMGPSGSGQLTKMVNQICIAGLV 202
Query: 652 MATAECMNMGH*NGTRT 702
A AE +N G T
Sbjct: 203 QALAEGVNFSEKVGLNT 219
>UniRef50_Q2BFK1 Cluster: Oxidoreductase; n=1; Bacillus sp. NRRL
B-14911|Rep: Oxidoreductase - Bacillus sp. NRRL B-14911
Length = 270
Score = 83.8 bits (198), Expect = 4e-15
Identities = 54/175 (30%), Positives = 82/175 (46%), Gaps = 1/175 (0%)
Frame = +1
Query: 151 MAANLVKKGFTVR-GYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILTSNKVVLDV 327
MA NL K G+ + ++ + G +S SIL ++K + V
Sbjct: 1 MAKNLQKNGYDLHITAHNNRKPVEELTSMGAVEHSSAADVVSNSEVIISILPADKEMESV 60
Query: 328 YLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLA 507
L ++ V+ G LI+ ++ P + K++ +KG+ D PVSGG GA+N TL
Sbjct: 61 LLSEE-VLNVLNPGQFLIEMTSGSPEMMKKVHAAYQQKGIPVLDGPVSGGTAGAENGTLT 119
Query: 508 FMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECM 672
MAGG + ER P+L+ M + G +G G+ K N ML GI A AE +
Sbjct: 120 VMAGGDADVLERLRPVLESMATNIYLVGSVGDGKAIKAINQMLAGIHMAAAAEAV 174
>UniRef50_Q019Z7 Cluster: Oxidoreductase-like; n=1; Ostreococcus
tauri|Rep: Oxidoreductase-like - Ostreococcus tauri
Length = 325
Score = 83.8 bits (198), Expect = 4e-15
Identities = 57/195 (29%), Positives = 89/195 (45%), Gaps = 1/195 (0%)
Frame = +1
Query: 97 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXX 276
++T +AFLG G MG MA NL+ G V ++ ++ A + G T A +
Sbjct: 39 TSTPMKLAFLGCGIMGVPMAKNLIAAGHDVTVWNRTESATKPVVEAGATLAKTASEAARA 98
Query: 277 XXXXXSILTSNKVVLDV-YLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGF 453
++++ + L V + K+G+ G +D ST+D + I + G F
Sbjct: 99 ADVVFVMVSTPEAALAVAHAAKEGL----SSGKGYVDVSTVDAGTSRAIAEVVRSTGAEF 154
Query: 454 TDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNM 633
+APVSG A++ L F+ G + + R L VMG F G +G G KL NM
Sbjct: 155 LEAPVSGSKKPAEDGALIFLCAGDEGLYTRCTDPLDVMGKAHFFLGDVGQGAKMKLVVNM 214
Query: 634 LMGITGMATAECMNM 678
+MG A AE + +
Sbjct: 215 IMGSMMGAFAEGLTL 229
>UniRef50_Q7WNK6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Bordetella bronchiseptica|Rep: 3-hydroxyisobutyrate
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 306
Score = 83.4 bits (197), Expect = 5e-15
Identities = 54/190 (28%), Positives = 82/190 (43%), Gaps = 1/190 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLG MGG + +L G V YD A+ AAA G PA S+
Sbjct: 9 IGFIGLGAMGGPICGHLAAAGHDVAAYDIQPAAVQAAAARGARPAASVREAADGAALLVV 68
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
++ + V G+ G A G+ + +ST+ P + + E G G D PVSG
Sbjct: 69 MVHNAGQADAVLFGEGGAAAALPAGATVWLASTVAPAYARGLQARLREHGAGLVDGPVSG 128
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITG 651
G GAQ L +A G+ + + P ++ + G + G+ KL N +L
Sbjct: 129 GATGAQAGALTIIASGQAQALAAAEPAMRACSSIIHRVGEEAGAASTVKLVNQLLTASHI 188
Query: 652 MATAECMNMG 681
TAE + +G
Sbjct: 189 ALTAEALALG 198
>UniRef50_Q1GF31 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=17; Proteobacteria|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Silicibacter sp. (strain TM1040)
Length = 325
Score = 83.0 bits (196), Expect = 7e-15
Identities = 48/174 (27%), Positives = 78/174 (44%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLGN+GG +A +L++ GF + YD + D + + G P +
Sbjct: 3 IGFIGLGNVGGKLAGSLLRNGFDLTVYDLNPDLVAEYVEKGAQPGTGPLAIMRACDAVIT 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
L S V + ++ + ++ ST D K++ + E+G + PVSG
Sbjct: 63 CLPSPAACATVV---EEMLPAVDSSKIWMEMSTTDAAEVKRLAALVSERGGSAMECPVSG 119
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 636
G A ++ AG + FER LP L +G + H G IGS + K+ N L
Sbjct: 120 GCHRADTGNISIFAGCDRATFERMLPTLTTLGRRVLHTGDIGSASILKVMTNYL 173
>UniRef50_A6VLT0 Cluster: 2-hydroxy-3-oxopropionate reductase; n=2;
Pasteurellaceae|Rep: 2-hydroxy-3-oxopropionate reductase
- Actinobacillus succinogenes 130Z
Length = 289
Score = 83.0 bits (196), Expect = 7e-15
Identities = 53/188 (28%), Positives = 93/188 (49%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+ V ++GLG MG MAA+L++ G V Y+ + + A G + +S+
Sbjct: 7 REVGWIGLGQMGEPMAAHLLEHGVKVGVYNRTAEKCQNVAAKGASVYSSVLELVKAYDVI 66
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
++ ++ V++ L ++ V A KG L+++ ST+ P +Q+ + + G F +APV
Sbjct: 67 F-VMVADFPVIESLLSEE--VLTALKGKLVVNMSTVSPTQNQQLEFLLAKHGAEFIEAPV 123
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
SG A+ L +A G++E E+ PL + F+ G++G KL N L+GI
Sbjct: 124 SGSSKVAEAGKLLVLAAGKEEIVEQLKPLFAAFSTQTFYYGEVGKAGGVKLMINSLLGIF 183
Query: 649 GMATAECM 672
A E +
Sbjct: 184 IQAYGEAL 191
>UniRef50_Q5FQ06 Cluster: Putative oxidoreductase; n=1;
Gluconobacter oxydans|Rep: Putative oxidoreductase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 290
Score = 82.6 bits (195), Expect = 9e-15
Identities = 55/189 (29%), Positives = 84/189 (44%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+G G M M ANL K G+ V Y PS K+ S
Sbjct: 6 IGFIGYGAMAQRMGANLRKAGYPVVAYAPS------GGKDETEMLPSPRAIAEAAEIIIF 59
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+ ++ + G++G +A G L++D+ST+ P+ +A+E G DAP+SG
Sbjct: 60 CVPNDAAENESLHGENGALAALTPGKLVLDTSTVSPDQADAFASLAVEHGFSLLDAPMSG 119
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
A+ L + GG + +R+ P+L V+G H G GS KL N +MG T
Sbjct: 120 STPEAETGDLVMLVGGDEAVVKRAQPVLDVIGKLTIHAGPAGSAARLKLVVNGVMGATLN 179
Query: 655 ATAECMNMG 681
AE ++ G
Sbjct: 180 VIAEGVSYG 188
>UniRef50_Q0UVR9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 288
Score = 81.8 bits (193), Expect = 2e-14
Identities = 55/136 (40%), Positives = 79/136 (58%), Gaps = 6/136 (4%)
Frame = +1
Query: 292 SILTSNKVVLDVYLG-KDGVVAHAK-KGSLLIDSSTIDPNVPKQIFPIALEKGLG-FTDA 462
SI+ K V VYL K GV+A K +G L+++ STID K++ E+GLG + DA
Sbjct: 27 SIVPGGKDVKTVYLDEKTGVIAARKDEGRLMLECSTIDVESTKEVGRKLKEEGLGTYIDA 86
Query: 463 PVSGGVMGAQNATLAFMAGGRKEDFERSLP-LLKVMG--AKQFHCGQIGSGQVAKLTNNM 633
PVSGGV A+ TL+ + G D LP L ++G +K F+ +G+G AK++NN
Sbjct: 87 PVSGGVPAAEAGTLSMLIGAPPPDPTSLLPSTLSLLGTPSKFFYLHTLGAGLTAKISNNY 146
Query: 634 LMGITGMATAECMNMG 681
L G +ATAE + +G
Sbjct: 147 LSGTILLATAEALAIG 162
>UniRef50_Q3W9W7 Cluster: 6-phosphogluconate dehydrogenase, NAD
binding domain; n=2; Frankia sp. EAN1pec|Rep:
6-phosphogluconate dehydrogenase, NAD binding domain -
Frankia sp. EAN1pec
Length = 286
Score = 81.0 bits (191), Expect = 3e-14
Identities = 56/194 (28%), Positives = 93/194 (47%), Gaps = 1/194 (0%)
Frame = +1
Query: 103 TDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXX 282
T +V F+GLGNMGG +AAN+ + G + +D + A G T + +
Sbjct: 2 TAPSVGFVGLGNMGGALAANVAQFGLDLVVHDAAGPE---RAPEGTTHLDDLAAVARHAE 58
Query: 283 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 462
+L+ V+ + + ++ + ++D+STI + ++I + G+G+ DA
Sbjct: 59 VV--VLSLPDGVISEKVARGLAETADRRVTHVVDTSTIGVSAAQRITDLLAASGIGYVDA 116
Query: 463 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLM 639
PVSGGV GA+ TL M G + R P+L + ++ G + G Q KL NN L
Sbjct: 117 PVSGGVTGARARTLTVMYAGTDDACARVEPVLAALSDRRRRVGDRPGLAQALKLANNFLA 176
Query: 640 GITGMATAECMNMG 681
+ AT+E + G
Sbjct: 177 AVALAATSEAVAFG 190
>UniRef50_A6VYD9 Cluster: 2-hydroxy-3-oxopropionate reductase
precursor; n=5; Gammaproteobacteria|Rep:
2-hydroxy-3-oxopropionate reductase precursor -
Marinomonas sp. MWYL1
Length = 300
Score = 81.0 bits (191), Expect = 3e-14
Identities = 58/193 (30%), Positives = 85/193 (44%), Gaps = 1/193 (0%)
Frame = +1
Query: 97 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXX 276
+N K+V +GLG+MG A + + G V G+D + AL G S
Sbjct: 2 TNKAKSVGVIGLGSMGMGAAKSCINAGLDVYGFDLNPKALEELNLAGAKAVASSALDFAD 61
Query: 277 XXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFT 456
+L N ++ L G+ A K + ++ S+TI K I + L
Sbjct: 62 QLDAVLVLVVNAKQVNSVLFDSGLAAALKPQTAVMVSATISAEDAKAIHQKLSQYQLLML 121
Query: 457 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNM 633
DAPVSGG A + MA G E FE+ P+L AK ++ G +IG G K+ + +
Sbjct: 122 DAPVSGGAAKAATGDMTVMASGSVEAFEKLQPVLDATAAKVYNIGEEIGLGATVKIIHQL 181
Query: 634 LMGITGMATAECM 672
L G+ A AE M
Sbjct: 182 LAGVHIAAGAEAM 194
>UniRef50_Q12H32 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Polaromonas sp. JS666|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 297
Score = 80.2 bits (189), Expect = 5e-14
Identities = 59/197 (29%), Positives = 91/197 (46%), Gaps = 6/197 (3%)
Frame = +1
Query: 109 KNVAFLGL-GNMGGFMAANLVKKGFTV-----RGYDPSKDALNAAAKNGVTPANSIXXXX 270
K++ +G G MG +A NL KGF + R + D L A AK +PA
Sbjct: 2 KHIGMIGASGLMGHGIARNLQAKGFDLSLTVHRNTERVADLLAAGAKQVASPAG-----L 56
Query: 271 XXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG 450
+T + V G DGV++ A G ++ID+ST +P +++ + E+G+
Sbjct: 57 GDCDAVIICVTGSPQVEQTLSGPDGVLSRALAGLIVIDTSTSEPESTRRLAALCAERGVT 116
Query: 451 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNN 630
DAP++ + A+ L M G + F++ P+L FH G G+G V KL NN
Sbjct: 117 LVDAPLARTPVEAELGRLNTMVGAEQAVFDKIRPVLAAYCENIFHVGGPGAGHVIKLLNN 176
Query: 631 MLMGITGMATAECMNMG 681
+ ATAE +G
Sbjct: 177 FIGQAICTATAEAFAVG 193
>UniRef50_Q1EPJ1 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein; n=8;
Magnoliophyta|Rep: 6-phosphogluconate dehydrogenase
NAD-binding domain-containing protein - Musa acuminata
(Banana)
Length = 314
Score = 80.2 bits (189), Expect = 5e-14
Identities = 59/190 (31%), Positives = 93/190 (48%), Gaps = 4/190 (2%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGY--DPSK-DALNAAAKNGV-TPANSIXXXXXXXX 282
V ++G G MG MAA L G+ V Y PSK D L + V +PA++
Sbjct: 18 VGWIGAGVMGAAMAARLQTAGYAVAIYARTPSKADHLRRLGAHLVPSPADAARSADVLFT 77
Query: 283 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 462
+ +LD G +A G +L+D ++ DP + +++ A +G DA
Sbjct: 78 MVGHPFDVREALLDP---ASGALAAIPPGGVLVDCTSSDPALAREVAAAARARGCWAVDA 134
Query: 463 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 642
PVSGG +GA++ TLA +AGG + PL + +G + G GSGQ +K+ N + +G
Sbjct: 135 PVSGGDVGARDGTLAILAGGDEGVVHWLSPLFEALGRATW-MGPAGSGQSSKIANQITIG 193
Query: 643 ITGMATAECM 672
T + +E +
Sbjct: 194 GTILGLSEAI 203
>UniRef50_Q0KC92 Cluster: 3-Hydroxyisobutyrate dehydrogenase; n=1;
Ralstonia eutropha H16|Rep: 3-Hydroxyisobutyrate
dehydrogenase - Ralstonia eutropha (strain ATCC 17699 /
H16 / DSM 428 / Stanier 337)(Cupriavidus necator (strain
ATCC 17699 / H16 / DSM 428 / Stanier337))
Length = 305
Score = 79.0 bits (186), Expect = 1e-13
Identities = 49/189 (25%), Positives = 84/189 (44%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ ++G+G MG M NL+K G+ + +D A A G A + S
Sbjct: 15 LGWIGVGAMGRPMCLNLLKAGYRLTVFDRVPAQCEAVAAAGAAVAPAAQALVADSDVVFS 74
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+ + + D++L GV A + +D ST+ P+ ++ +G F APVSG
Sbjct: 75 TIFDDGGLRDLFLASGGVAGAATADKVFVDMSTVSPDASAEVAAALARRGAAFLRAPVSG 134
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
V A +A L+ G + F+ P+L + A+Q + G +V KL NM++ ++
Sbjct: 135 TVSLAASAQLSCFVSGPRPAFDAVQPVLACLTARQSYVGGADEARVIKLMINMMVFMSTA 194
Query: 655 ATAECMNMG 681
E + G
Sbjct: 195 VIGEGLAFG 203
>UniRef50_A1GFG2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Salinispora arenicola CNS205|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Salinispora arenicola CNS205
Length = 315
Score = 79.0 bits (186), Expect = 1e-13
Identities = 53/193 (27%), Positives = 82/193 (42%), Gaps = 2/193 (1%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKG-FTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
++ LGLG MG M L+ G + ++ + +A + G A +
Sbjct: 2 HITMLGLGAMGSRMTRRLIATGEHDITVWNRTAEATRPLVEAGAVAAPTPAAATAQSDLV 61
Query: 289 XSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 465
S+L + V+L D G + G+L +D ST+ P +++ ++G F DAP
Sbjct: 62 ISMLRDVEAGRSVWLDPDVGALTSLAPGTLAVDCSTVTPTFSRELAACCAQRGAEFLDAP 121
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 645
V G A TL F+AGG R P+L+ +G H G G+G KL N L +
Sbjct: 122 VLGSRPQADAGTLIFLAGGDLAVLHRIEPVLRQVGGAVHHMGPAGTGTQMKLLTNSLFAV 181
Query: 646 TGMATAECMNMGH 684
AE + H
Sbjct: 182 QVATVAELIAALH 194
>UniRef50_A3EW86 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep:
3-hydroxyisobutyrate dehydrogenase - Leptospirillum sp.
Group II UBA
Length = 279
Score = 78.6 bits (185), Expect = 1e-13
Identities = 55/169 (32%), Positives = 82/169 (48%), Gaps = 2/169 (1%)
Frame = +1
Query: 139 MGGFMAANLVKKGFTVRGYDPSKDAL--NAAAKNGVTPANSIXXXXXXXXXXXSILTSNK 312
MG M L+ G V GY+ + L + TPA+ I + ++++
Sbjct: 1 MGVRMVRRLLDNGIPVTGYNRTAGRLPSHPLFHAAHTPAD-IAEKSDLIFLMVTDGSASR 59
Query: 313 VVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQ 492
+L+ G DG+ + GSL+I+ STI P ++ L KG G+ D PVSG ++ A+
Sbjct: 60 ALLE---GPDGIARGLRPGSLVINMSTIAPEEAQEEALSLLAKGAGYLDVPVSGSLVPAE 116
Query: 493 NATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM 639
L +AGG ER+ P+L G K H G GSG AKL N+L+
Sbjct: 117 KGELLLLAGGDGAALERARPILLHFGKKILHFGPTGSGMKAKLVINLLL 165
>UniRef50_P71825 Cluster: Uncharacterized oxidoreductase
Rv0770/MT0794; n=18; Corynebacterineae|Rep:
Uncharacterized oxidoreductase Rv0770/MT0794 -
Mycobacterium tuberculosis
Length = 295
Score = 78.2 bits (184), Expect = 2e-13
Identities = 52/188 (27%), Positives = 80/188 (42%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ ++GLGN G MA L+ + +D +A+ + G T A S+ +
Sbjct: 10 LGYIGLGNQGAPMAKRLLDWPGGLTVFDVRVEAMAPFVEGGATAAASVSDVAEADIISIT 69
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+ +V V +G+ HAK G+++ STI + +G+ DAPVSG
Sbjct: 70 VFDDAQVS-SVITADNGLATHAKPGTIVAIHSTIADTTAVDLAEKLKPQGIHIVDAPVSG 128
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G A LA M G E F+R + H G+ G+G KL NML ++
Sbjct: 129 GAAAAAKGELAVMVGADDEAFQRIKEPFSRWASLLIHAGEPGAGTRMKLARNMLTFVSYA 188
Query: 655 ATAECMNM 678
A AE +
Sbjct: 189 AAAEAQRL 196
>UniRef50_Q20XN2 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodopseudomonas palustris BisB18|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodopseudomonas palustris (strain BisB18)
Length = 365
Score = 77.8 bits (183), Expect = 2e-13
Identities = 55/187 (29%), Positives = 87/187 (46%), Gaps = 1/187 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V +GLG MG A NL+ G + +D + ++A A+ GV A + S
Sbjct: 23 VGVVGLGRMGRAFAENLLADGHPIVVWDAFQTQIDAMARPGVVAATKLADLAECDVVFSS 82
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
L ++ V V G G+V K G++ I STI P + +++ E G G+ APV G
Sbjct: 83 -LPDDEAVTAVAAGAGGLVKIMKAGAVHISMSTISPTMSRRLAAWHGECGQGYVAAPVLG 141
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQ-IGSGQVAKLTNNMLMGITG 651
A+ TL +A G +++ PLL +G K F G+ + + KL N+L +T
Sbjct: 142 NPDLARARTLFILAAGPDAAMQKARPLLDRLGQKLFVIGEDAAAANLVKLAGNVLTALTL 201
Query: 652 MATAECM 672
+ E +
Sbjct: 202 QSMGEVL 208
>UniRef50_Q8PK98 Cluster: 3-hydroxyisobutirate dehydrogenase; n=3;
Proteobacteria|Rep: 3-hydroxyisobutirate dehydrogenase -
Xanthomonas axonopodis pv. citri
Length = 300
Score = 77.4 bits (182), Expect = 3e-13
Identities = 54/193 (27%), Positives = 80/193 (41%), Gaps = 3/193 (1%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
++ +G+GN+G A + +G V +D AL A + G T A +
Sbjct: 2 DIGLVGMGNIGRHFVARWLAQGHRVIVHDTRAQALQQAKEAGATTAAGMADVLANAEVIA 61
Query: 292 SILTSNKVVLDVY--LGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 465
L VVL+V L + L++D ST ++ + + F AP
Sbjct: 62 LSLPLPSVVLEVARTLAAAAAATEMRDSLLVVDLSTTGAQTTSEVGHLLERADVSFLSAP 121
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNMLMG 642
VSGG A L MA G +ER+ PLL +G F+ G + GQ KL NN L
Sbjct: 122 VSGGTAAAAQGVLTVMAAGPLAAYERARPLLDAVGRHIFYLGGDVRLGQTLKLINNTLYA 181
Query: 643 ITGMATAECMNMG 681
+A+ E + G
Sbjct: 182 SAMLASCEALVCG 194
>UniRef50_Q9LM23 Cluster: Fructose-bisphosphate aldolase; n=2;
Arabidopsis thaliana|Rep: Fructose-bisphosphate aldolase
- Arabidopsis thaliana (Mouse-ear cress)
Length = 1486
Score = 77.4 bits (182), Expect = 3e-13
Identities = 67/209 (32%), Positives = 91/209 (43%), Gaps = 13/209 (6%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPS---------KDALNAAAKNGVTPANSIXXX 267
+ F+GLG MG MAA+L+K F+V GYD S K L G ANS
Sbjct: 348 IGFIGLGAMGFGMAAHLLKSNFSVCGYDISLRLAVSSVYKPTLVRFENAGGLAANSPAEV 407
Query: 268 XXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALE--- 438
++T+ DV G G V G+ ++ +ST+ P Q+ LE
Sbjct: 408 TKDVDVLVIMVTNEVQAEDVLYGHLGAVEAIPSGATVVLASTVSPAFVSQL-ERRLENEG 466
Query: 439 KGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVA 615
K L DAPVSGGV A L MA G E + + +L + K + G G+G
Sbjct: 467 KDLKLVDAPVSGGVKRAAMGELTIMASGTDEALKSAGLVLSALSEKLYVIKGGCGAGSGV 526
Query: 616 KLTNNMLMGITGMATAECMNMGH*NGTRT 702
K+ N +L G+ + AE M G G T
Sbjct: 527 KMVNQLLAGVHIASAAEAMAFGARLGLNT 555
Score = 41.1 bits (92), Expect = 0.026
Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
Frame = +1
Query: 457 DAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC-GQIGSGQVAKLTNNM 633
DA V G+ + L +A GR + R+ P L M + G+IG+G K+ N +
Sbjct: 145 DAYVLKGMSELLDGKLMIIASGRSDSITRAQPYLTAMCQNLYTFEGEIGAGSKVKMVNEL 204
Query: 634 LMGITGMATAECMNMG 681
L GI +A E +++G
Sbjct: 205 LEGIHLVAAVEAISLG 220
>UniRef50_Q0C8I2 Cluster: Predicted protein; n=3;
Pezizomycotina|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 320
Score = 77.4 bits (182), Expect = 3e-13
Identities = 67/209 (32%), Positives = 96/209 (45%), Gaps = 13/209 (6%)
Frame = +1
Query: 94 SSNTDKNVAFLGLGNMGGFMAANLVKK---GFTVRGYDPSKDALN---AAAKNGVTPANS 255
SS + ++ F+GLG MG MA L+ + +D + A+N A + S
Sbjct: 2 SSLSSDDIGFIGLGAMGLPMAQQLIANVPAPTRLYVFDIADQAMNDFVAMYPHKAVAGKS 61
Query: 256 IXXXXXXXXXXXSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDP--NVPKQIFP 426
+++ V VYL + GV + LLID STID ++ +
Sbjct: 62 PRDVAEHSKTIITMVPEGSHVRAVYLDESTGVCSTPLDTRLLIDCSTIDTATSLAVKAHI 121
Query: 427 IALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPL----LKVMGAKQFHCGQ 594
F DAPVSGGV+GAQ +AF G K D +LPL L++MG + CG
Sbjct: 122 TTHHASASFYDAPVSGGVLGAQKGAIAFFLGCAKTD--PNLPLLTDTLRLMGKEVIPCGG 179
Query: 595 IGSGQVAKLTNNMLMGITGMATAECMNMG 681
G AKL NN L G+ +A +E +N+G
Sbjct: 180 PSLGLSAKLCNNYLSGLIAIANSEALNIG 208
>UniRef50_Q9HLR4 Cluster: Putative uncharacterized protein Ta0161;
n=2; Thermoplasma|Rep: Putative uncharacterized protein
Ta0161 - Thermoplasma acidophilum
Length = 290
Score = 77.4 bits (182), Expect = 3e-13
Identities = 58/196 (29%), Positives = 85/196 (43%), Gaps = 1/196 (0%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKD-ALNAAAKNGVTPANSIXXXXXXXXX 285
K V +GLG MG +AAN G YD + D A N A+ V +
Sbjct: 8 KKVLLVGLGVMGSRIAANFASAGKLAGVYDRNVDKAKNTASMLKVGFYRDLGEAVKNSDI 67
Query: 286 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 465
++L ++ V +VY + V +G + ID STI P+ +I EKG DAP
Sbjct: 68 IVTMLYDDRSVKEVYSQMEQGV----QGKVFIDMSTISPDTSIEIAKRIKEKGGKMYDAP 123
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 645
V G + + L + GG ++ L+ + + G GSG AKL NN+ +G
Sbjct: 124 VIGTSIAVEKKALVVLVGGDLSGYDEVRDLISATANQVVYMGDNGSGLYAKLVNNLFLGS 183
Query: 646 TGMATAECMNMGH*NG 693
+ AE + G NG
Sbjct: 184 YMASLAEAVRFGRKNG 199
>UniRef50_UPI0001597301 Cluster: YfjR; n=1; Bacillus
amyloliquefaciens FZB42|Rep: YfjR - Bacillus
amyloliquefaciens FZB42
Length = 286
Score = 76.6 bits (180), Expect = 6e-13
Identities = 48/176 (27%), Positives = 84/176 (47%), Gaps = 1/176 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+A +GLGNMG +A N++K G+++ Y+ +K+ G A + S
Sbjct: 3 IAIVGLGNMGRPIAENIMKAGYSLTVYNRTKEKAADLLDKGAEYAETPRQAAEHADIVLS 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L+ + V DV G G++A + + I STI + +Q+ +G F APV G
Sbjct: 63 MLSDDDAVTDVTFGACGIIAGLSENGIHISMSTISTALSEQLSAAHSGRGQSFIAAPVLG 122
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLM 639
A+ A L + G E +++ PLL ++ + F G + + AK++ N L+
Sbjct: 123 RPDAAEKAELRIITAGPAEAKKKAEPLLNILSQQVFDTGEETKTANAAKISVNFLL 178
>UniRef50_Q0BTJ3 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Granulibacter bethesdensis CGDNIH1|Rep:
2-hydroxy-3-oxopropionate reductase - Granulobacter
bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
Length = 293
Score = 76.6 bits (180), Expect = 6e-13
Identities = 60/193 (31%), Positives = 90/193 (46%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+A LG G MG +MA L G V ++ + AA+ G+ A S
Sbjct: 9 IAVLGTGIMGRWMACRLADAGHEVTVWNRNPVR---AAELGLPVATSAPDAAHGADVAL- 64
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
++ S+ D L V A+ G++L+ SS Q ++ + DAPVSG
Sbjct: 65 LMVSDGPACDAVLETGFVDTMAQNGTVLVMSSIEPWRARAQAKKVSPRF---YVDAPVSG 121
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G GA+N TLA MAGG + R P+ +G + G IG+GQ+AKL N +++G+T
Sbjct: 122 GEGGARNGTLAIMAGGEEAVLNRLAPVFAALG-RMTRIGDIGAGQLAKLANQLIVGVTIG 180
Query: 655 ATAECMNMGH*NG 693
A +E + G
Sbjct: 181 AVSEAFVLAEAGG 193
>UniRef50_Q6F842 Cluster: Putative 3-hydroxyisobutyrate
dehydrogenase or 2-hydroxy-3- oxopropionate reductase;
n=2; Acinetobacter|Rep: Putative 3-hydroxyisobutyrate
dehydrogenase or 2-hydroxy-3- oxopropionate reductase -
Acinetobacter sp. (strain ADP1)
Length = 291
Score = 76.2 bits (179), Expect = 8e-13
Identities = 50/196 (25%), Positives = 88/196 (44%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+AF+G+G MG MA LV+ GF+V ++ ++ A + G +
Sbjct: 9 IAFIGMGLMGSRMATRLVQAGFSVAVWNRTQSACDVLLDMGAQALS--LEKIADYPVILM 66
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
L ++ V VY + V + +++D S++ N K + A ++ + D+PVSG
Sbjct: 67 CLADDQAVNHVY---EQVHHLVRPQQIIVDFSSLSVNQTKYLADRAQQQQAIWIDSPVSG 123
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
G GA+ TL AGG + + + V+ + G G+GQ K+ N +++
Sbjct: 124 GTSGAEQGTLVIFAGGNESTIQDLGLIYNVLSQRVTRMGDTGTGQATKICNQLIVAANSA 183
Query: 655 ATAECMNMGH*NGTRT 702
AE + + H G T
Sbjct: 184 LIAEAVALAHRAGVDT 199
>UniRef50_O66454 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyisobutyrate
dehydrogenase - Aquifex aeolicus
Length = 288
Score = 76.2 bits (179), Expect = 8e-13
Identities = 53/198 (26%), Positives = 91/198 (45%), Gaps = 1/198 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKN-GVTPANSIXXXXXXXXXXX 291
V F+GLG++G +A L+++G + ++ + + AK G +S
Sbjct: 3 VGFIGLGHLGRAIAKRLIEQGVELIVWNRTLSKAHEFAKETGAEVTSSPADLINKVDRVF 62
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
I+ ++ +V G+ G+V KG +ID +T ++ + + G + DAPV
Sbjct: 63 VIVFDSQASEEVIFGEKGLVKGDIKGKTVIDMTTNHYLYAQKAYEELKKLGAFYLDAPVL 122
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
G V+ A L + GG KE FE + PL + ++ G+ G G KL NN+++G
Sbjct: 123 GSVIPALKGELTIVVGGDKEKFEENKPLFEKFCRAIYYLGEAGMGSKMKLVNNIVLGGIM 182
Query: 652 MATAECMNMGH*NGTRTE 705
AE + +G G E
Sbjct: 183 EVLAEAIAIGEKAGIDKE 200
>UniRef50_A4ECY9 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 359
Score = 76.2 bits (179), Expect = 8e-13
Identities = 53/198 (26%), Positives = 85/198 (42%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
+VAF+G G MG +A +++ G+ V + +K A + G A +
Sbjct: 6 SVAFIGTGIMGAPIAGHILDAGYPVTVNNRTKSKAAALIERGAVWAETPADAVVNADVVF 65
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
+++ V ++YL DG++ K G++LID +T P + + I A G D PV+
Sbjct: 66 TMVGYPSEVEELYLAGDGLLTCTKPGAVLIDLTTSSPELARDIAEAAQVSGRMAFDCPVT 125
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
GG GA TL + G + D +L A G GQ AKL N + +
Sbjct: 126 GGESGAIAGTLTAIVGATENDIAPVRDVLSTFAANICCFDGAGKGQAAKLANQVSLAACM 185
Query: 652 MATAECMNMGH*NGTRTE 705
+ A+ M +G E
Sbjct: 186 VGMADAMAFAELSGLDLE 203
>UniRef50_Q7VYY0 Cluster: Putative oxidoreductase; n=4;
Bordetella|Rep: Putative oxidoreductase - Bordetella
pertussis
Length = 305
Score = 75.8 bits (178), Expect = 1e-12
Identities = 56/196 (28%), Positives = 88/196 (44%), Gaps = 8/196 (4%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLV-KKGFTVRGYDPSKDALNAAAKNGV----TPANSIXXXXX 273
+ + F+GLG MG M NL + + + YD S A + A +
Sbjct: 3 QTLGFVGLGMMGLPMLENLAGDERWQILAYDRSPAPFERLAGHPAWGKRLRAAAGLQELA 62
Query: 274 XXXXXXSILTSNKVVLDVYLGKDG---VVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKG 444
++L ++ + V LG DG ++ + G+ ++D + +P +++ +G
Sbjct: 63 ACDTVITMLPNSAITNAVVLGGDGQPGLIDLLESGAAIVDMGSSNPADTRRLSEQLAARG 122
Query: 445 LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLT 624
L DAPVSG V A TLA MAG + D R P+L+ MGA H G +GS K
Sbjct: 123 LTLIDAPVSGAVAKASTGTLAIMAGAAEADLRRVRPILERMGAAIIHTGAVGSAHAMKAL 182
Query: 625 NNMLMGITGMATAECM 672
NN + +A +E M
Sbjct: 183 NNYVYAAGLLAVSEAM 198
>UniRef50_Q9LNP0 Cluster: F1L3.35; n=8; Magnoliophyta|Rep: F1L3.35 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 387
Score = 75.8 bits (178), Expect = 1e-12
Identities = 40/116 (34%), Positives = 61/116 (52%)
Frame = +1
Query: 319 LDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNA 498
+DV GK+G + G +D ST+D I + G F +APVSG A++
Sbjct: 166 IDVACGKNGAIFGISSGKGYVDVSTVDVASSILISKQIKDTGALFLEAPVSGSKKPAEDG 225
Query: 499 TLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAE 666
L F+ G K +E++ P L +MG +F+ G++G+G KL NM+MG + AE
Sbjct: 226 QLIFLTAGDKPLYEKAAPFLDIMGKSKFYLGEVGNGAAMKLVVNMIMGSMMASFAE 281
>UniRef50_A7H7Z5 Cluster: 6-phosphogluconate dehydrogenase
NAD-binding; n=2; Anaeromyxobacter|Rep:
6-phosphogluconate dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 293
Score = 75.4 bits (177), Expect = 1e-12
Identities = 57/195 (29%), Positives = 83/195 (42%), Gaps = 2/195 (1%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKG--FTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+ F+GLG +G +A NL K G TV PSK A + +K G A S
Sbjct: 5 IGFVGLGTIGEPIANNLRKAGHDLTVWNRTPSK-AAHIVSKGGKL-AGSARECATGRDLV 62
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
+ ++ K + V G DGV+ + G +L+D ST + + A +G GF PV
Sbjct: 63 ITCVSDEKALDTVLEGPDGVLEALRDGDVLVDMSTAGVRAARSVSERAAARGAGFVACPV 122
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
G A+ A L +AGG ER+ P L + A+ F + KL N + G
Sbjct: 123 LGSRSAAEQAQLVLVAGGPAVARERARPALHAVSARIFELEDAAQAALMKLCVNAIGGAM 182
Query: 649 GMATAECMNMGH*NG 693
E + +G G
Sbjct: 183 ITGFGEALALGQAGG 197
>UniRef50_A0JRK4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=3; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 299
Score = 75.4 bits (177), Expect = 1e-12
Identities = 55/188 (29%), Positives = 89/188 (47%), Gaps = 2/188 (1%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ LGLG MG MA L + TV G+D ++ L A + G+ S
Sbjct: 7 ITVLGLGAMGLPMATRLASQ-LTVHGFDIAEPRLKLAEEAGIRTFASAREASEGADALLL 65
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPN-VPKQIFPIALEKGLGFTDAPVS 471
+ + + + DV G +GV + K G+++I ST+ + +P + +A E G+ DAP+S
Sbjct: 66 AVRNGEQLNDVLFGANGVASVLKPGAVVILGSTVGTDAIPATVDRLA-EYGVELVDAPLS 124
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGIT 648
GG A L + G E E++ P L+++ + G + G GQ K N +L G+
Sbjct: 125 GGPKRAGEGDLLIVVGASPEAQEKARPALELLASTLTVVGDKPGDGQALKTVNQLLCGVH 184
Query: 649 GMATAECM 672
A AE +
Sbjct: 185 IAAAAEAL 192
>UniRef50_Q74D68 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=7; Desulfuromonadales|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Geobacter sulfurreducens
Length = 288
Score = 74.1 bits (174), Expect = 3e-12
Identities = 55/191 (28%), Positives = 76/191 (39%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+ V FLGLG +G MAANL+K + + YD A+ A G T A +
Sbjct: 3 RKVGFLGLGTVGRHMAANLLKGNYELAVYDSDPAAVADLAALGATGAATPREVAKGRDIV 62
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
I + + G DG+ A G++L+D T ++ A + + F DAPV
Sbjct: 63 IHIRPEKERLRPDIYGPDGIFAGIDPGTILVDMGTHSLTSTMEMADEAAKHRVMFLDAPV 122
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
G A N L +AGG R L G H G IG K N++
Sbjct: 123 WGTKEHAANGLLTILAGGDPSLVGRCRELFSFFGLNIIHVGSIGDATRMKFVVNLVQAEL 182
Query: 649 GMATAECMNMG 681
A AE + G
Sbjct: 183 MQALAESIVFG 193
>UniRef50_A3LTC4 Cluster: 3-hydroxyisobutyrate dehydrogenase-like
protein; n=6; Saccharomycetales|Rep:
3-hydroxyisobutyrate dehydrogenase-like protein - Pichia
stipitis (Yeast)
Length = 355
Score = 74.1 bits (174), Expect = 3e-12
Identities = 70/234 (29%), Positives = 107/234 (45%), Gaps = 30/234 (12%)
Frame = +1
Query: 67 LYTAAR---RAYSSNT--DKNVAFLGLGNMGGFMAANLVKK-------------GFTVRG 192
+Y A+R R +SS + + F+GLG MG MA ++ K +
Sbjct: 1 MYKASRICTRHFSSTSMASTSYGFIGLGQMGQHMARHIYNKLEATDKLYVNDNVAAATQS 60
Query: 193 YDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS-ILTSNKVVLDVYLGKDGVVAHAKKG 369
+ + N A K+ + P NS+ I+T V +V+H +K
Sbjct: 61 FIKNVTDENPANKDALKPLNSLEEFVTSVDEPLDFIITMVPEGKHVKGVVSELVSHYQKN 120
Query: 370 SL------LIDSSTIDPNVPKQIFPIALEK--GLGFTDAPVSGGVMGAQNATLAFM-AGG 522
++ +DSSTID +++ ++ G F D PVSGGV GA+ ATL+FM +
Sbjct: 121 NVSGTKTTFLDSSTIDIPTSREVHEFVKKELPGADFIDTPVSGGVAGARKATLSFMLSRP 180
Query: 523 RKEDFERSL-PLLKVMGAKQFHCGQI-GSGQVAKLTNNMLMGITGMATAECMNM 678
E L LL MGA F CG+ G+G AKL+NN L+ +T +A A+ +
Sbjct: 181 NNESISADLRTLLNKMGANIFACGETHGAGLAAKLSNNYLLAVTNLAVADSFQL 234
>UniRef50_A5P600 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Methylobacterium sp. 4-46|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Methylobacterium sp. 4-46
Length = 290
Score = 73.7 bits (173), Expect = 4e-12
Identities = 56/196 (28%), Positives = 87/196 (44%), Gaps = 3/196 (1%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ ++GLG +G MA +LV G V +D +D AA G A+ +
Sbjct: 3 IGWIGLGKLGAPMARHLVAAGHAVLAFD--RDPGRLAAVPGAEAAD--LPGVAACGVVVT 58
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
L + + V LG +G++A +L+++ST+ P + A G+ + APVSG
Sbjct: 59 SLPDDAALAAVALGPEGLLARMAPDGVLVETSTVSPETSAALREAAEAGGILYLAAPVSG 118
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVA---KLTNNMLMGI 645
A+ ATL G + ER+ PLL A+ H +G G+ A KL N +G
Sbjct: 119 STATAEAATLTLFCSGPETALERARPLLATF-ARTIHA--VGPGEEARFLKLAINHFVGS 175
Query: 646 TGMATAECMNMGH*NG 693
T AE + + G
Sbjct: 176 TAQVAAEALTLARRGG 191
>UniRef50_A0YMN9 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Cyanobacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Lyngbya sp. PCC 8106
Length = 371
Score = 73.7 bits (173), Expect = 4e-12
Identities = 53/201 (26%), Positives = 86/201 (42%), Gaps = 4/201 (1%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ +G GN+G AAN + G++V YD + + G +S +
Sbjct: 19 LGIIGCGNIGKRQAANFLAHGYSVYVYDINPARMAQLQSLGAHITHSCAELATHCEVIFT 78
Query: 295 IL-TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV- 468
L T + + V G+ + + GS+ ID +T P ++ G+ D P
Sbjct: 79 ALPTPSDTIKAVLEGEQNLSQGLRSGSIYIDITTNSPETIHRLHQAISPLGVEMLDVPFN 138
Query: 469 --SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 642
S G LA +A G + FER PLL++M + +CG+IGSG KL +N +
Sbjct: 139 DCSEGATSEGGMGLAVLASGSRATFERVEPLLQLMADQVLYCGEIGSGTRCKLIHNAVNA 198
Query: 643 ITGMATAECMNMGH*NGTRTE 705
+ A +E + +G G E
Sbjct: 199 VAVQAVSEGITLGLAQGISLE 219
>UniRef50_Q5LNV6 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=2;
Rhodobacteraceae|Rep: 3-hydroxyisobutyrate dehydrogenase
- Silicibacter pomeroyi
Length = 269
Score = 73.3 bits (172), Expect = 5e-12
Identities = 50/174 (28%), Positives = 77/174 (44%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ G G MG M A L + GF +G+D + +G+T + + +
Sbjct: 2 IGVAGCGRMGAPMLAALRRAGFQAQGFDIRPSSDFPGTDHGIT--DGVAVFSQNLCTLIT 59
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
++ V L D + HAK +I ST+ P + + + + DAP+SG
Sbjct: 60 VVRDISQTEQV-LFTDQKLIHAKHLDCVIICSTLSPRYVRDL-RARVPDHIALIDAPMSG 117
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 636
+ AQ A L+FM GG D + + PL MG+ G GSG AK+ NN+L
Sbjct: 118 AQIAAQEARLSFMLGGEPADLDAAQPLFAAMGSHFHRMGPYGSGMQAKVLNNLL 171
>UniRef50_A7RG59 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 341
Score = 73.3 bits (172), Expect = 5e-12
Identities = 55/211 (26%), Positives = 94/211 (44%)
Frame = +1
Query: 40 ARTILSTQCLYTAARRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALN 219
AR + L+ AA +S + + V +G GN+G +A L K +V+ +D ++ N
Sbjct: 4 ARFLARNAFLWRAAFSMSTSASPRTVGLVGTGNVGSAVAVGLRKIDVSVKAFDLQQNNYN 63
Query: 220 AAAKNGVTPANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTID 399
G T NS + L + V L G+++ K+GS+ ID +T D
Sbjct: 64 FLESTGTTLVNSPEEVTKDVDVLITALPKPQHVKSA-LEDTGMLSMLKEGSVWIDHTTTD 122
Query: 400 PNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQ 579
N ++ +A KG+ +AP++GG + GG ++ + PL+ A
Sbjct: 123 YNETIRLGELATSKGVHAVEAPLTGG-----QGLMTVFVGGEEKVVQDVKPLMDSYTATF 177
Query: 580 FHCGQIGSGQVAKLTNNMLMGITGMATAECM 672
+ G +G VAK+ +NML +A E +
Sbjct: 178 LYFGPLGKATVAKVISNMLCAAHLVAAGEAL 208
>UniRef50_Q55JR1 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 605
Score = 73.3 bits (172), Expect = 5e-12
Identities = 53/196 (27%), Positives = 89/196 (45%), Gaps = 8/196 (4%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V ++GLG MG MAA+LV +G+ V+ +D +L A+ G P++S
Sbjct: 9 VGWIGLGAMGSGMAASLVSQGYKVQAFDVYPPSLKRVAEQGAIPSSSPRDAAEGVQVLCL 68
Query: 295 ILTSNKVVLDVYLGKDGVVAH-AKKGSLLIDSSTIDPNVPKQIFP--IALEKGLGFTDAP 465
++ + + V + GKDG VA K G+ +I ST+ P+ ++ L K +G D+P
Sbjct: 69 MVVNAQQVEETLFGKDGGVAEILKNGASIIVFSTVPPSFLVEVARRLDKLGKNIGLVDSP 128
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVM-----GAKQFHCGQIGSGQVAKLTNN 630
VSGG A LA M+ G + +L + G ++G K+ N
Sbjct: 129 VSGGSTRAAQGQLAIMSSGTPSSIATARTVLDSLTLPPQGGLTLVGDRVGIASDFKMINQ 188
Query: 631 MLMGITGMATAECMNM 678
+ ++ A E + +
Sbjct: 189 VFCAVSIAAQGEALGL 204
Score = 33.5 bits (73), Expect = 5.2
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 8/88 (9%)
Frame = +1
Query: 427 IALE-KGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERS---LPLLKVMGAK----QF 582
+A+E K L DAP +GG A+ +L A G + S L L + G F
Sbjct: 411 LAIEIKPLQLIDAPTAGGSKEAKGGSLTVFASGEADALSASHSILSALSIQGGDPTKLHF 470
Query: 583 HCGQIGSGQVAKLTNNMLMGITGMATAE 666
G +GS K N++L I T E
Sbjct: 471 IAGGVGSATKVKAVNSLLEAIHLAVTGE 498
>UniRef50_A5WG80 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=2; Moraxellaceae|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Psychrobacter sp. PRwf-1
Length = 309
Score = 72.9 bits (171), Expect = 7e-12
Identities = 57/189 (30%), Positives = 82/189 (43%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
+V+F+GLG MG MA +LV TV Y+ + D A A T A S+
Sbjct: 17 SVSFIGLGAMGHHMAKHLVGSFDTVMVYNRNFDKATAHAAEFGTQAVSLEQAVSADVIF- 75
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
S L +++VV D+ + + H GS+ +D ++ P K G F DAPVS
Sbjct: 76 SCLPTSQVVDDLI---EQALPHLNDGSVWVDCTSGVPENAKASQAKLNAAGCEFLDAPVS 132
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
G GA + TL M GG + + + H G G+G K NN L I
Sbjct: 133 GQTSGADSGTLTVMVGGSAKALAYAKSAIDCFAGLIVHVGDSGAGFAVKAVNNTLFAINA 192
Query: 652 MATAECMNM 678
A E +++
Sbjct: 193 WAAVEGLSV 201
>UniRef50_A0GI22 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Burkholderia phytofirmans PsJN|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Burkholderia phytofirmans PsJN
Length = 355
Score = 72.9 bits (171), Expect = 7e-12
Identities = 37/83 (44%), Positives = 49/83 (59%)
Frame = +1
Query: 445 LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLT 624
+G+ DAPVSGGV GA TLA MAGG D E PLL ++ H G +G+GQ AKL
Sbjct: 175 IGWIDAPVSGGVAGATAGTLAVMAGGAAADVEAVKPLLGAYASRVTHMGDVGAGQTAKLC 234
Query: 625 NNMLMGITGMATAECMNMGH*NG 693
N ++ T A AE +++ +G
Sbjct: 235 NQTIVTATLAAIAEAVSLAQRSG 257
>UniRef50_Q98K09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=7;
Alphaproteobacteria|Rep: 3-hydroxyisobutyrate
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 312
Score = 72.5 bits (170), Expect = 9e-12
Identities = 51/178 (28%), Positives = 78/178 (43%), Gaps = 2/178 (1%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGF--TVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXX 282
+ + F+GLG MG +A N+V KG+ T G K A + + G A++
Sbjct: 8 EKIGFIGLGLMGHGIAKNIVDKGYPLTFLGRKNRKPAEDLLGR-GAREASTSRDVAVASD 66
Query: 283 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 462
+T ++ V + G G+ KKGS+++D ST DP + G+ + DA
Sbjct: 67 IVFICVTGSREVEAIIRGPGGLKEGLKKGSVVVDCSTSDPVSTVALAAELKALGIDYVDA 126
Query: 463 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 636
P+S A TL M G F R P+++ + H G G G KL NN +
Sbjct: 127 PLSRTPKEAWEGTLDAMVGAPDAVFARVKPVIETWAGRIVHIGDTGDGHRMKLLNNFI 184
>UniRef50_A1UJF3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Actinomycetales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Mycobacterium sp. (strain KMS)
Length = 272
Score = 72.5 bits (170), Expect = 9e-12
Identities = 52/190 (27%), Positives = 79/190 (41%), Gaps = 1/190 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV-TPANSIXXXXXXXXXXX 291
V F+G G MG M LV G TV + + AA+ G T A +
Sbjct: 4 VGFVGAGRMGAPMVRRLVGAGHTVTALGRTPEKRAAASDLGAATAAEPVDVATGADIVVV 63
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
+ T ++V G G++A G+ L+ +T P+ + + + G+ DAPVS
Sbjct: 64 CVFTDDQVRAVCLDG--GLLAAMAPGATLVIHTTGSPDTARLLAARGRDHGVDVVDAPVS 121
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
GG + GG + ER+ P+L G H G +G+GQ KL NN +
Sbjct: 122 GGPHDIAAGAVTLFVGGSEAAVERARPVLAAYGDPILHVGPLGAGQSVKLVNNTVFAAQI 181
Query: 652 MATAECMNMG 681
E + +G
Sbjct: 182 GLLREAVRLG 191
>UniRef50_A0R1N5 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium smegmatis
(strain ATCC 700084 / mc(2)155)
Length = 263
Score = 72.5 bits (170), Expect = 9e-12
Identities = 51/175 (29%), Positives = 73/175 (41%), Gaps = 1/175 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTP-ANSIXXXXXXXXXXX 291
+ FLG G MG M L G V + + A A +G TP A +
Sbjct: 3 IGFLGAGRMGAPMVQRLTAAGHDVHALGRTDEKRTAVAGSGATPVAAATDAVHGADVVIV 62
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
+ T +V L D ++ G++L+ +T P + I A ++G+ DAPVS
Sbjct: 63 CVFTDEQVRT---LCTDTLLDAMAPGAVLVLHTTGSPRTAEDIAARAADRGVAVVDAPVS 119
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 636
GG ++ AGG + ER P L H G +GSGQ KL NN +
Sbjct: 120 GGPHDIAAGSVTVFAGGDADVVERVRPALVAYAEPLLHVGPLGSGQRVKLVNNTM 174
>UniRef50_Q4Q9Z1 Cluster: Dehydrogenase-like protein; n=6;
Trypanosomatidae|Rep: Dehydrogenase-like protein -
Leishmania major
Length = 431
Score = 72.5 bits (170), Expect = 9e-12
Identities = 55/206 (26%), Positives = 90/206 (43%), Gaps = 15/206 (7%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTV-------RGYDPSKDALNAAAKNGVTPANSIXXXX 270
NV +G+GNMG + NL K + R ++ + + +G T A I
Sbjct: 9 NVGVVGMGNMGIPITRNLAFKARSAMYLQIHSRTLSKARQVCDDMSADGATCAMRIHDRY 68
Query: 271 XXXXXXXSIL--------TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFP 426
++ S KV+L+ + +V +A+ G +++D +T+D + ++
Sbjct: 69 STMTKWCDVILLTLAHRAASRKVLLE---DSEALVTNARPGQIIVDHTTVDMELSRECAH 125
Query: 427 IALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSG 606
A +G F DAP+SG A N L M GG E +R P+ ++ H G GSG
Sbjct: 126 EAERRGAVFLDAPMSGSPKQAFNNQLVLMVGGPAEQVQRVSPIFRMYADHIHHMGANGSG 185
Query: 607 QVAKLTNNMLMGITGMATAECMNMGH 684
AKL + L+ A AE M + +
Sbjct: 186 TAAKLLSQALVASHNAAAAEAMTIAN 211
>UniRef50_Q8F4I7 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4;
Leptospira|Rep: 3-hydroxyisobutyrate dehydrogenase -
Leptospira interrogans
Length = 296
Score = 72.1 bits (169), Expect = 1e-11
Identities = 48/174 (27%), Positives = 82/174 (47%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
++ +G G MG MA NL K G ++R Y + + K+ V +S
Sbjct: 7 ISIIGTGIMGRGMAVNLAKAGHSLRLYTRNLSKIQDLKKDNVQIFDSPIEAAKNSDLVVL 66
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
LT +++V + G++ K +LID T ++ ++ + EK + F D+P++G
Sbjct: 67 CLTEDQIVEKETISS-GLLD--TKPPILIDCGTTSLSLTLKLSKLCSEKKIRFYDSPMTG 123
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 636
A++ + FM G ++ D + +V G +CG IG GQ AKL NM+
Sbjct: 124 SKNAARDGQILFMIGAKQVDIKDIQFFFEVCGKNAVYCGSIGGGQKAKLALNMI 177
>UniRef50_Q3WJ00 Cluster: 6-phosphogluconate dehydrogenase, NAD
binding domain; n=1; Frankia sp. EAN1pec|Rep:
6-phosphogluconate dehydrogenase, NAD binding domain -
Frankia sp. EAN1pec
Length = 438
Score = 72.1 bits (169), Expect = 1e-11
Identities = 54/198 (27%), Positives = 77/198 (38%)
Frame = +1
Query: 88 AYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXX 267
+Y F+GLG+MG MA L +G + Y +L A T A +
Sbjct: 163 SYHDEDTVKTGFIGLGSMGLPMAQRLQSQGHDLTLYARRPASLEPFAGTSATIAATPAEM 222
Query: 268 XXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGL 447
+ V +V G DG+ G++++ ST+ P ++I A GL
Sbjct: 223 GASVDAVGICVFDAAGVEEVMFGPDGLAGTLNPGAVVLVHSTVAPAQIRRIAGRAATHGL 282
Query: 448 GFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTN 627
DAPVSGG A L M GG + LL + H G +G+G AKL N
Sbjct: 283 RVLDAPVSGGQPRALAGELTIMIGGDADTLADVAELLSALSNHVVHLGAVGAGSYAKLIN 342
Query: 628 NMLMGITGMATAECMNMG 681
N + + M G
Sbjct: 343 NTMFAAQIALADDAMKAG 360
>UniRef50_Q7Q161 Cluster: ENSANGP00000013149; n=11; Culicidae|Rep:
ENSANGP00000013149 - Anopheles gambiae str. PEST
Length = 581
Score = 72.1 bits (169), Expect = 1e-11
Identities = 47/184 (25%), Positives = 78/184 (42%)
Frame = +1
Query: 121 FLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSIL 300
FLGLG MG + NL+K G +V ++ S + G A++ S +
Sbjct: 300 FLGLGVMGCGIVKNLIKSGHSVVVWNRSAHKCRKFQEVGAEVADTPSDVVEMTDVTYSCV 359
Query: 301 TSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGV 480
+ +V D+ G GV++ G ++ + +DP I + KG + +A + G
Sbjct: 360 SDPQVAKDMVFGNCGVMSANLAGKGYVEMTGVDPETSNDINEAIISKGGRYLEAQIQGSK 419
Query: 481 MGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAT 660
A+ TL +A G + FE + + F+ G +G+ L M+ GIT
Sbjct: 420 NQAEEGTLIILASGDRLLFEECQSCFEAISRNSFYLGDVGNATKMNLILQMISGITLAGV 479
Query: 661 AECM 672
AE M
Sbjct: 480 AEAM 483
>UniRef50_A3H9B3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Caldivirga maquilingensis IC-167
Length = 293
Score = 72.1 bits (169), Expect = 1e-11
Identities = 43/141 (30%), Positives = 68/141 (48%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V +GLG MGG L+ KGF + YD +D +N K G T A+S +
Sbjct: 3 VGLVGLGRMGGAFGRVLLSKGFNLVVYDVVRDKVNEFVKLGATGASSPADLASRVDIVLT 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+ ++ VLDVYLG +G+++ AK G + +++ST D ++ + +GF A +
Sbjct: 63 NVPRSEDVLDVYLGGNGILSGAKPGLIAVETSTTDIKTKLRVAEECRRRNVGFIVAMLGK 122
Query: 475 GVMGAQNATLAFMAGGRKEDF 537
V A+ GG +E F
Sbjct: 123 TVPQAERGETPLFVGGPEEVF 143
>UniRef50_Q9RX16 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=6;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Deinococcus radiodurans
Length = 310
Score = 71.7 bits (168), Expect = 2e-11
Identities = 53/183 (28%), Positives = 81/183 (44%)
Frame = +1
Query: 118 AFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSI 297
AFLGLG MG MAA+L + + G + A A++ A S +
Sbjct: 21 AFLGLGAMGFPMAAHLAAQAASGGGRALVWNRTEAKAQDHAARAGSEAVSLADTAQADVL 80
Query: 298 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 477
T +V + H + G++ +D ++ P+ ++ G+ F DAPVSGG
Sbjct: 81 FTCLPTSAEVDEIIAALSPHLRPGTVWVDCTSGHPDAARRQRETLDALGVKFLDAPVSGG 140
Query: 478 VMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMA 657
GA+ TL M GG ++ + + P L G K G+ G+G K NNML+ + A
Sbjct: 141 TSGAEAGTLTVMLGGPADEIDAASPHLAFAG-KVVRVGETGAGFAVKAVNNMLLAVNLWA 199
Query: 658 TAE 666
E
Sbjct: 200 AGE 202
>UniRef50_Q7NEW9 Cluster: Glr3759 protein; n=3; Bacteria|Rep:
Glr3759 protein - Gloeobacter violaceus
Length = 290
Score = 71.3 bits (167), Expect = 2e-11
Identities = 51/184 (27%), Positives = 81/184 (44%), Gaps = 1/184 (0%)
Frame = +1
Query: 118 AFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSI 297
A LG+G MG MAA L+K G V ++ + A+ G A + +
Sbjct: 5 AVLGMGAMGSRMAAALLKAGHQVTVWNRNSQKTAPLAEMGAKAAQTPRAAVEEVDFAVCM 64
Query: 298 LTSNKVVLDVYLG-KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+ + V+L + G +A ++ I+SST+ +++ +G DAPVSG
Sbjct: 65 VRDDAASRFVWLDFETGALAGLPADAVAIESSTLSVAGVQELAEHFQARGKTLLDAPVSG 124
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
A+ L F+ GG ++ P+L MG H G +G+G KL N L+G+
Sbjct: 125 SRPQAEAGQLIFLVGGDAGAVAKAGPILNAMGGTVHHAGPLGNGAAVKLAINALLGVQVA 184
Query: 655 ATAE 666
A E
Sbjct: 185 AMGE 188
>UniRef50_Q21ZN3 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodoferax ferrireducens T118|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodoferax ferrireducens (strain DSM 15236 / ATCC
BAA-621 / T118)
Length = 292
Score = 71.3 bits (167), Expect = 2e-11
Identities = 52/191 (27%), Positives = 83/191 (43%), Gaps = 3/191 (1%)
Frame = +1
Query: 97 SNTDKNVAFLGLGNMGGFMAANLVKKGF--TVRGYDPSKDALNAAAKNGVTPANSIXXXX 270
SNT + +GLG MG + NL+K GF TV G + ++ +++ G + S+
Sbjct: 3 SNTSLRIGLIGLGLMGHGIGRNLLKNGFALTVMG-NVNRAPVDSLVSLGANESKSVAELV 61
Query: 271 XXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG 450
+T + V + G++ + G ++ID ST P+ I LE G
Sbjct: 62 DASDVVMLCVTGSPQVESLMNRDQGILQSIRPGQIVIDCSTSQPSSSAIINAALLEAGAL 121
Query: 451 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNN 630
F DAP+ A+ L M G + E P+L+ H G++ S Q KL NN
Sbjct: 122 FVDAPLGRTPAEAEAGKLNVMVGATPQLLEHIRPVLQAFCENIIHVGEVISAQKLKLINN 181
Query: 631 M-LMGITGMAT 660
++G + T
Sbjct: 182 FAVVGTAALLT 192
>UniRef50_Q033P2 Cluster: 3-hydroxyisobutyrate dehydrogenase related
beta-hydroxyacid dehydrogenase; n=1; Lactobacillus casei
ATCC 334|Rep: 3-hydroxyisobutyrate dehydrogenase related
beta-hydroxyacid dehydrogenase - Lactobacillus casei
(strain ATCC 334)
Length = 285
Score = 71.3 bits (167), Expect = 2e-11
Identities = 52/176 (29%), Positives = 84/176 (47%), Gaps = 3/176 (1%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+G+G+MG M +L K G+ V +D + A A + V A S+ +
Sbjct: 3 ITFIGVGDMGSHMVPHLAKAGYDVTVWDKVPAKMAAVAGDHVRTATSLEDAVTASRVIIT 62
Query: 295 ILTSNKVVLDVYLGKD---GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 465
+ S+ V +++G G+V + + GS LI +ST+DP I + K D P
Sbjct: 63 SVMSDDVPA-LHIGTTETPGIVHYLQPGSTLIVTSTLDPRKITAIQAVMPTK-THLLDVP 120
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNM 633
+ GGV A+ A L +A G K+ P+LK G ++ G+ G+G KL N+
Sbjct: 121 MIGGVKYAREAGLVLIAAGDKQAVADVTPILKTFGTVKY-VGEQGNGAKLKLITNV 175
>UniRef50_A7DWL2 Cluster: Putative dehydrogenase; n=1; Streptomyces
tendae|Rep: Putative dehydrogenase - Streptomyces tendae
Length = 293
Score = 70.9 bits (166), Expect = 3e-11
Identities = 50/186 (26%), Positives = 79/186 (42%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
VA +GLG MG MA L++ GF V ++ S AA+ G A S
Sbjct: 5 VAVIGLGGMGSGMALALLRAGFQVTVFNRSPQKAEQAARAGAAVAPSAGAAGAAARVVLL 64
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
L V +V G+ VV + G++L+D++T+ P+ + G+ +A V G
Sbjct: 65 SLADEPAVDEVLFGE--VVWQLQPGTVLVDTTTVSPSFARNTAVRLAASGVERLEACVMG 122
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
A++ L G + + +L +G + H G G KL N+L+GI
Sbjct: 123 NPEMAESGRLRIFTSGSHSAVDAAGDVLSALGQEVRHLGDAGRASALKLALNLLLGIQTA 182
Query: 655 ATAECM 672
AE +
Sbjct: 183 GLAEAV 188
>UniRef50_A3Y8R5 Cluster: Putative dehydrogenase; n=1; Marinomonas
sp. MED121|Rep: Putative dehydrogenase - Marinomonas sp.
MED121
Length = 297
Score = 70.9 bits (166), Expect = 3e-11
Identities = 50/193 (25%), Positives = 88/193 (45%), Gaps = 4/193 (2%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVK----KGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXX 282
+ F+GLGNMG MAANL++ + D +++ ++ G A+S+
Sbjct: 3 IGFIGLGNMGSGMAANLLEYCKANHNELLVLDLNQEVVSQFVDKGARKADSVKHVAQECD 62
Query: 283 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 462
+ L S+ V + G++G++ +A+ G+ ++ST + + +++ IA L DA
Sbjct: 63 VIFTSLPSSVQVNHIAFGEEGILENAQAGATWFETSTNELSEWEKVKAIA-PSHLSLIDA 121
Query: 463 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 642
PV+GG GA TL + G ++ + +L G G+G V KL L
Sbjct: 122 PVTGGAEGAAAGTLTMLLGIDEQILTKFTSMLNAFTKNAIRMGPSGAGYVTKLAQLHLNY 181
Query: 643 ITGMATAECMNMG 681
+ E + MG
Sbjct: 182 LVAQGIGEALMMG 194
>UniRef50_A0RU56 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: 3-hydroxyisobutyrate
dehydrogenase - Cenarchaeum symbiosum
Length = 282
Score = 70.9 bits (166), Expect = 3e-11
Identities = 47/176 (26%), Positives = 73/176 (41%)
Frame = +1
Query: 139 MGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILTSNKVV 318
+G + L+K G V Y+ + D A G A S + +T +
Sbjct: 2 LGTGIGLRLLKTGINVIAYNRTADKTKALEDAGARIAKSPGEAAGLSDTVITCVTDADAL 61
Query: 319 LDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNA 498
V G++G+ A K +L D STI+P I + G+ DAPV GG A
Sbjct: 62 EQVSFGENGIAQGAHKDLVLCDMSTINPEGAVSISKKLADAGIRMVDAPVMGGPGAAMRG 121
Query: 499 TLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAE 666
L MA G K +E +L + K F+ G G+ KL N+ + + ++ +E
Sbjct: 122 ELVIMASGDKGAYEERRGILGAVSRKMFYLGGSGTAYSIKLAMNLQIAMLAISLSE 177
>UniRef50_A6R0U9 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 444
Score = 70.1 bits (164), Expect = 5e-11
Identities = 61/210 (29%), Positives = 92/210 (43%), Gaps = 9/210 (4%)
Frame = +1
Query: 103 TDK-NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSI-XXXXXX 276
T+K ++ F+GLG MG MA NL+K G+ V+GYD + + G A+S
Sbjct: 3 TEKPSIGFVGLGLMGFGMATNLIKLGYVVKGYDIQETTMARFKDAGGQIASSPGGAAGGN 62
Query: 277 XXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTID----PNVPKQIFPIALEKG 444
+ T+ + + ++ ++G+ G+ LI ST+ + Q+ I E
Sbjct: 63 MFCVCMVATAAQAQVAIFDHENGIAKGLPSGATLILCSTVSAVSAQSYRDQLVSIGRE-D 121
Query: 445 LGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQ---FHCGQIGSGQVA 615
+ F DAPVSGG A TL MAGG E LL M F G +G+G
Sbjct: 122 VYFIDAPVSGGARKAGEGTLTIMAGGSDAALEEGKFLLTEMADTNKLYFVPGGVGAGSNM 181
Query: 616 KLTNNMLMGITGMATAECMNMGH*NGTRTE 705
K+ + + I +A +E M G E
Sbjct: 182 KMIHQVFAAIHILAASEVMGFAAHLGLNAE 211
>UniRef50_A6RMW8 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 446
Score = 69.7 bits (163), Expect = 7e-11
Identities = 63/213 (29%), Positives = 100/213 (46%), Gaps = 10/213 (4%)
Frame = +1
Query: 97 SNTDKN-VAFLGLGNMGGFMAANLVKKGFTVRGYD---PSKDALNAAAKNGVTPANSIXX 264
S++DK VAF+GLG MG MA NL+K F+V G+D P+ + +A N T S
Sbjct: 2 SSSDKPAVAFIGLGAMGMGMATNLLKT-FSVTGFDVYEPTLEKFRSAGGNTATTPRSAVA 60
Query: 265 XXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDP-NVP--KQIFPIAL 435
+ T+ + + ++ G + + + +I SST P +VP +++
Sbjct: 61 NAQYIVIM--VATAAQTLAVLFDDVTGAIHELQPNATIILSSTAFPEHVPEVRELLDNKY 118
Query: 436 E-KGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC--GQIGSG 606
K + DAPVSGG A TL +A G ++ + + P+L M A H G +G+G
Sbjct: 119 NRKDVELVDAPVSGGTSRAALGTLVILASGPEKSLDAAKPVLDAM-ADPLHMIPGGLGAG 177
Query: 607 QVAKLTNNMLMGITGMATAECMNMGH*NGTRTE 705
K+ + L GI + +E M G T+
Sbjct: 178 TKVKMVHQALAGIHMIMASEAMGFAAFLGLNTK 210
>UniRef50_Q5GUM4 Cluster: Dehydrogenase; n=5;
Gammaproteobacteria|Rep: Dehydrogenase - Xanthomonas
oryzae pv. oryzae
Length = 335
Score = 69.3 bits (162), Expect = 9e-11
Identities = 61/228 (26%), Positives = 94/228 (41%), Gaps = 5/228 (2%)
Frame = +1
Query: 16 RKNKFKMAARTILSTQCLYTAA--RRAYSSNTDKNVAFLGLGNMGGFMAANLVKKGFTVR 189
R+++ AA C T RR + FLGLG MG MA NL++ GF +
Sbjct: 11 RRHRNTCAANRATRAACSPTDPYPRRHTEQGQRMPIGFLGLGTMGLPMAHNLLRGGFELS 70
Query: 190 GYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKG 369
++ S + G T S+L + V L + GV+ G
Sbjct: 71 VWNRSPERAQPLRDAGATVVEQ-PCGAAHGPLLFSMLADDDAVRQTLLER-GVLDALPAG 128
Query: 370 SLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSL 549
S+ ++ +TI + + + E+G+ + APV G V A+ L +AGG R
Sbjct: 129 SVHVNMATISVALAHALTALHAERGVAYVAAPVLGRVDVAEAGKLNILAGGDDVAVARVQ 188
Query: 550 PLLKVMGAKQFHCGQI-GSGQVAKLTNNMLM--GITGMATAECMNMGH 684
P+ +G K +H G+ AKL N+ + I MA A + GH
Sbjct: 189 PMFDALGQKTWHIGRAPEQANAAKLAANVCLASAIGAMAEASALARGH 236
>UniRef50_Q0RIL5 Cluster: Putative uncharacterized protein; n=1;
Frankia alni ACN14a|Rep: Putative uncharacterized
protein - Frankia alni (strain ACN14a)
Length = 493
Score = 69.3 bits (162), Expect = 9e-11
Identities = 44/171 (25%), Positives = 84/171 (49%)
Frame = +1
Query: 124 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILT 303
+GLG +GG +A ++ ++G +D DA A G + +++T
Sbjct: 13 VGLGMIGGGVAVSMARRGRVPAVHDVRPDASAALPGVGDPLGSPAEVARSSDVVMVAVVT 72
Query: 304 SNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVM 483
+++ DV G++G++A A G ++ ST++ V ++ + E +GF D V+ G
Sbjct: 73 ADQA-RDVIGGENGLLAGAHPGLTIVLLSTVELAVVHELAALCAEHDVGFLDCGVTPGDR 131
Query: 484 GAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 636
A + +A + GG + E + P+L + HCG +G+G V K+ N++
Sbjct: 132 AADHGMVA-IVGGDEATVEAARPVLDDWARRVVHCGPLGAGMVTKIARNVV 181
>UniRef50_Q39KK8 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=34; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 289
Score = 68.9 bits (161), Expect = 1e-10
Identities = 47/177 (26%), Positives = 82/177 (46%), Gaps = 1/177 (0%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
++ F+GLG MG +A NL+K G TVR ++ S++ A G ++
Sbjct: 2 DLGFIGLGEMGQAIATNLLKAGHTVRVWNRSRERAEPLAAIGAQIVDT-PADAFRGDAVF 60
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
S+L + ++ D ++A A +G + ++ +T+ + + + +G+ + APV
Sbjct: 61 SMLADDAAARAIF--DDALLAQAPRGLIHVNMATVSVALAESLAHAHASRGIHYVAAPVM 118
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGS-GQVAKLTNNMLM 639
G A A L MAGG E +R PL +G K + G + VAK+ N +
Sbjct: 119 GRPDVAAAARLTIMAGGPAEAIDRVQPLFDAIGQKTWRFGSLPQHANVAKIAANFTL 175
>UniRef50_Q120Q9 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=7; Burkholderiales|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 297
Score = 68.5 bits (160), Expect = 2e-10
Identities = 48/177 (27%), Positives = 76/177 (42%), Gaps = 1/177 (0%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYD-PSKDALNAAAKNGVTPANSIXXXXXXXXX 285
K + +G+G MG +A+N++K G+ + + P L G T +S
Sbjct: 2 KKIGMVGIGMMGHGIASNIIKHGYPMVLLEHPGNQPLQGLIAAGATTTDSAATLAGVVDI 61
Query: 286 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 465
+T V DV K G++ K G+++ID ST P+ +I + G F DAP
Sbjct: 62 IILCVTGTPEVEDVLYRKGGLLEGIKPGTIVIDCSTAIPSSTIRIAESVEKAGGRFLDAP 121
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 636
++ A L + GG FE P+L+ G +GSG KL +N +
Sbjct: 122 MTRTPKEAAEGRLNLIVGGDPALFESCKPVLECYAENIVLAGPVGSGHRLKLLHNFV 178
>UniRef50_Q1V2K7 Cluster: NADP oxidoreductase, coenzyme
F420-dependent:6- phosphogluconatedehydrogenase,
NAD-binding:3-hydroxyacyl-CoA; n=1; Candidatus
Pelagibacter ubique HTCC1002|Rep: NADP oxidoreductase,
coenzyme F420-dependent:6-
phosphogluconatedehydrogenase,
NAD-binding:3-hydroxyacyl-CoA - Candidatus Pelagibacter
ubique HTCC1002
Length = 284
Score = 68.1 bits (159), Expect = 2e-10
Identities = 45/177 (25%), Positives = 79/177 (44%), Gaps = 1/177 (0%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVK-KGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 285
KNV F+G+G MG +A N++K K + ++ + G S
Sbjct: 2 KNVGFIGVGYMGYGIAKNILKNKNNLFVIANKNRSPIEKIVSEGAVEVKSYDELCSKDLD 61
Query: 286 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 465
+ +N + + K ++ +L+ID +T D N + I K + + + P
Sbjct: 62 CLFLCVTNTPIAHSIIEK--ILPLLNSDTLIIDITTHDQNGSIEANKIFKSKNINYIECP 119
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 636
V GG + A+ L + GG +E+F+++ LK F+ G++G G +KL NN L
Sbjct: 120 VMGGPVQAEEGVLGGIIGGSEENFKKAEVFLKAFCKDYFYFGEVGMGTKSKLLNNFL 176
>UniRef50_A1SQ87 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=4; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Nocardioides sp. (strain
BAA-499 / JS614)
Length = 318
Score = 68.1 bits (159), Expect = 2e-10
Identities = 46/185 (24%), Positives = 89/185 (48%), Gaps = 1/185 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V ++G G MG MA+ L + G V ++ ++ A ++ G A++I
Sbjct: 13 VGWIGAGRMGAAMASRLARAGEDVTVWNRTRAKAEALSEVGCGVADTIADLRGHDVVFTM 72
Query: 295 ILTSNKVVLDVYLGKDGVVAH-AKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
+ T + V +G+ G++A A+ ++++D ST+ + E+G+ F APVS
Sbjct: 73 VSTPADLE-QVLVGEGGLLADPARVPAVVVDCSTVSTESSAAMRAACSERGVAFLAAPVS 131
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITG 651
G + L+ + G +E +ER LL +G + G+ ++AK+ +N+++G+
Sbjct: 132 GNGKVVRAGGLSLVVSGPEETYERVAHLLDHLGKGATYVGEGELARLAKICHNVMLGVVT 191
Query: 652 MATAE 666
AE
Sbjct: 192 QCLAE 196
>UniRef50_Q4WXG9 Cluster: 3-hydroxyisobutyrate dehydrogenase,
putative; n=1; Aspergillus fumigatus|Rep:
3-hydroxyisobutyrate dehydrogenase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 317
Score = 68.1 bits (159), Expect = 2e-10
Identities = 49/139 (35%), Positives = 70/139 (50%), Gaps = 3/139 (2%)
Frame = +1
Query: 292 SILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALE--KGLGFTDA 462
+++ + V VYL GV+ + +L+D STID + + K F DA
Sbjct: 84 TMVPEGRHVRSVYLDSHAGVLTTSVDDKILVDCSTIDTATSMDVGAAVCQNSKTAAFYDA 143
Query: 463 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 642
PVSGG +GA TL FM G ++D P L+++ F CG G AKL NN G
Sbjct: 144 PVSGGSLGAVAGTLTFMVGCVEDD-----PNLELL---IFPCGGFLLGLTAKLCNNYCSG 195
Query: 643 ITGMATAECMNMGH*NGTR 699
+ +ATAE MN+G +G +
Sbjct: 196 LIAIATAEAMNIGIKSGMK 214
>UniRef50_Q9I1R8 Cluster: Probable dehydrogenase; n=7; Pseudomonas
aeruginosa|Rep: Probable dehydrogenase - Pseudomonas
aeruginosa
Length = 291
Score = 67.7 bits (158), Expect = 3e-10
Identities = 50/176 (28%), Positives = 80/176 (45%), Gaps = 1/176 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V FLGLG MG MA LV+ G V ++ S A G A + S
Sbjct: 3 VGFLGLGGMGAAMATRLVQAGLEVTVWNRSAAACEPLVALGAARAEEVGELFGLDVVI-S 61
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L ++ + V L G + A+ G + + ST+ + + + +GL F APV G
Sbjct: 62 MLADDQAIRGVLLDS-GALERARPGLIHLSMSTLSLDCVEALDQAHQRQGLAFVAAPVFG 120
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVA-KLTNNMLM 639
A+ L + GG +E E+ LL++MG K + G+ G +A K++ N ++
Sbjct: 121 RTDVAEAGKLNIVVGGPEEAIEQVKALLEIMGQKTWFFGKDPRGAMAVKISGNFMI 176
>UniRef50_A0K107 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Arthrobacter sp. FB24|Rep: 2-hydroxy-3-oxopropionate
reductase - Arthrobacter sp. (strain FB24)
Length = 302
Score = 67.7 bits (158), Expect = 3e-10
Identities = 54/194 (27%), Positives = 86/194 (44%), Gaps = 7/194 (3%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGV--TPANSIXXXXXXXXX 285
+VA +G G MG +A N++ + ++ + + A V TPA +
Sbjct: 17 SVALIGTGPMGAPIARNILAGHVPLTLWNRTAEKARAIGGGTVVATPAAAASEVVL---- 72
Query: 286 XXSILTSNKVVLDVYLGKDGVVAHAKKGSL----LIDSSTIDPNVPKQIFPIALEK-GLG 450
++L V + G+DG++A K + L+ T+ P + L GL
Sbjct: 73 --TVLPDLPQVAALLPGEDGLLAGWKAAGIEHPVLVIHGTVSPVAVAEFADDCLRNWGLT 130
Query: 451 FTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNN 630
DAP+SGG +GA+ L+ M GG E ER PL + + H G+ G+G K N
Sbjct: 131 VVDAPLSGGTIGAEEGRLSIMVGGPAEAVERLTPLFGLYSSTAVHFGKTGAGSTVKACNQ 190
Query: 631 MLMGITGMATAECM 672
+++ T A AE M
Sbjct: 191 IVVAATVNALAEAM 204
>UniRef50_Q6RXW5 Cluster: Succinic semialdehyde dehydrogenase; n=2;
Rhodococcus|Rep: Succinic semialdehyde dehydrogenase -
Rhodococcus sp. TK6
Length = 262
Score = 67.3 bits (157), Expect = 3e-10
Identities = 53/191 (27%), Positives = 90/191 (47%), Gaps = 1/191 (0%)
Frame = +1
Query: 124 LGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILT 303
+GLG +GG + A+L + G V GYD +++ L ++ +PA S S+
Sbjct: 5 IGLGPIGGKIGAHLAELGRKVYGYDFNQERLREWSEETASPAGS-DLAAVDWPSIDSVHV 63
Query: 304 SNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVM 483
+ ++ V + + AH + + +T+ P ++I P A G +APVSGG
Sbjct: 64 AVRLADQVSSVFEALAAHTAQPLTVFVHTTLAPADARKILPSA-PAGWRVFEAPVSGGPQ 122
Query: 484 GAQNATL-AFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMAT 660
GA++ ++ F+AG D E + LL+ + + F G + KL NN L AT
Sbjct: 123 GARHGSMTVFLAGPAPTDAENA--LLEDISGRVFQMESYGQPALVKLLNNALATYNLAAT 180
Query: 661 AECMNMGH*NG 693
A +N+ +G
Sbjct: 181 ARMLNLAAEHG 191
>UniRef50_Q82ZC2 Cluster: 6-phosphogluconate dehydrogenase family
protein; n=16; Bacteria|Rep: 6-phosphogluconate
dehydrogenase family protein - Enterococcus faecalis
(Streptococcus faecalis)
Length = 299
Score = 66.9 bits (156), Expect = 5e-10
Identities = 47/191 (24%), Positives = 85/191 (44%), Gaps = 2/191 (1%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
++ F+GLG MG MA N+ ++G+ + G+D +K+A A + G++ +S+
Sbjct: 2 DIGFIGLGKMGLNMALNVHEQGWPIIGFDVTKEARATAREQGLSVVDSLSELLKALNKRK 61
Query: 292 SILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVS 471
I S +V +++DS + + +A EKG+ F D S
Sbjct: 62 VIFLSTPAGQITNQLVAELVEQLAPEDIIVDSGNSNFHDSVANAQLAKEKGIYFIDCGTS 121
Query: 472 GGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQ--FHCGQIGSGQVAKLTNNMLMGI 645
GG+ GA+ M GG E + P + + +Q + G+ G+G K+ +N + +
Sbjct: 122 GGIKGAREGA-CLMVGGAPEAVKVLTPFFEDLACEQGYLYAGKSGAGHYLKMVHNGIEYV 180
Query: 646 TGMATAECMNM 678
A E N+
Sbjct: 181 MMQAMGEGFNL 191
>UniRef50_A3ET09 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxyisobutyrate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 311
Score = 66.9 bits (156), Expect = 5e-10
Identities = 44/187 (23%), Positives = 85/187 (45%), Gaps = 2/187 (1%)
Frame = +1
Query: 124 LGLGNMGGFMAANLVKKGFTVRG-YDPSKDALNAAA-KNGVTPANSIXXXXXXXXXXXSI 297
+G+G MG MA L G+ V YD +A A + G + A ++ ++
Sbjct: 14 VGVGRMGSNMALRLNDVGYRVASVYDVRLEAARRVADETGASVARTLAEVTAQSDVIITV 73
Query: 298 LTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGG 477
+ +++ + ++ + G + ++ +T+ P++ ++ + ++G +A ++
Sbjct: 74 VGTDREMDALFAETGDSLLVGASGRVFVNCATLSPDIHVEVERRSNDRGADCLEASMASS 133
Query: 478 VMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMA 657
+ A+ TL M GG+KE FER P+L+ M A G G K NM+M I
Sbjct: 134 ITQAREGTLYLMVGGKKEAFERVRPVLEAMSASLRWIGPAGQAAKIKALVNMVMNINTAG 193
Query: 658 TAECMNM 678
AE + +
Sbjct: 194 LAEGLGL 200
>UniRef50_Q2JEN4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Frankia sp. CcI3|Rep:
6-phosphogluconate dehydrogenase, NAD-binding - Frankia
sp. (strain CcI3)
Length = 290
Score = 66.5 bits (155), Expect = 6e-10
Identities = 51/185 (27%), Positives = 79/185 (42%), Gaps = 1/185 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ F+GLG MG MA NL+ G TV ++ S D + A G PA+ S
Sbjct: 3 IGFIGLGGMGSAMARNLIDAGHTVLAWNRSPDPVTELAAAGAVPAS--ISEAFATGIVLS 60
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L ++ V D L V+ A G+L ++ +T+ + Q E GL + APV G
Sbjct: 61 MLADDQAVTDRLL-DPRVLTAAPAGALHVNMATVSTALAIQARREHAEHGLRYLAAPVFG 119
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGS-GQVAKLTNNMLMGITG 651
A+ L + G + PL V+G + + G + K+ N L+ +
Sbjct: 120 RTDAARAGNLTIVTSGDPDTIAEVQPLFDVLGRRTWTVGDAPEHANLVKILGNYLIACSI 179
Query: 652 MATAE 666
A AE
Sbjct: 180 EAMAE 184
>UniRef50_Q221W9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Rhodoferax ferrireducens T118|Rep:
2-hydroxy-3-oxopropionate reductase - Rhodoferax
ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118)
Length = 303
Score = 66.1 bits (154), Expect = 8e-10
Identities = 49/206 (23%), Positives = 81/206 (39%), Gaps = 3/206 (1%)
Frame = +1
Query: 97 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAK---NGVTPANSIXXX 267
S + V F+G+G MG MA +++ KG V K A +G P +
Sbjct: 5 STSSLKVGFIGVGMMGCGMAKHVLAKGHPVALLIRKKADEERCADLLTHGAQPLKTAAEV 64
Query: 268 XXXXXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGL 447
+T + V +V G G++ K G +++D ST P+ +++ KG
Sbjct: 65 AATADVIIICVTGSPQVEEVVFGDTGILQTLKPGCVVVDCSTSLPDSTRRVAQAIAAKGG 124
Query: 448 GFTDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTN 627
F DA ++G A L + GG E P+ + F+CG + +G KL +
Sbjct: 125 QFLDAAMTGTPKHADEGKLNLLVGGDPEVLTSVRPVFALFAENIFYCGAVSAGHTTKLLH 184
Query: 628 NMLMGITGMATAECMNMGH*NGTRTE 705
++ AE + G E
Sbjct: 185 QFVVLGNAAILAEAFSCASKTGVNLE 210
>UniRef50_A0AWL7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=1; Arthrobacter sp. FB24|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Arthrobacter sp. (strain FB24)
Length = 297
Score = 66.1 bits (154), Expect = 8e-10
Identities = 52/190 (27%), Positives = 87/190 (45%), Gaps = 3/190 (1%)
Frame = +1
Query: 112 NVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXX 291
+V +GLG MG +AA+L+ +V +D D + A G P+ S
Sbjct: 5 HVGVVGLGGMGKALAASLIAADHSVAVWDRHTDRVATTAMIGAAPSVSPRQLAEQSHVIF 64
Query: 292 SILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFP--IALEKGLGFTDA 462
L + V +V ++ GV+A + G+L++D +T DP + + + AL G + DA
Sbjct: 65 LALPNPTAVREVLYDEEAGVLAGLRAGALIVDMTTGDPELAQDVAQRVAALGNGARYVDA 124
Query: 463 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMG 642
PVSG A N T+ M GG + +++ + + G +G G KL + +
Sbjct: 125 PVSGT---APNLTV--MIGGEAGVLGGAESIVQDVAGTLLYAGALGDGFATKLVHQHVKY 179
Query: 643 ITGMATAECM 672
T +A AE +
Sbjct: 180 ATHLAVAEAL 189
>UniRef50_Q392H4 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=8; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 292
Score = 65.7 bits (153), Expect = 1e-09
Identities = 52/191 (27%), Positives = 81/191 (42%), Gaps = 3/191 (1%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
VA LG+G MG +A NL ++GFTVR ++ ++ +A A +GV + +
Sbjct: 12 VAVLGIGVMGAPIARNLARQGFTVRAWNRTRAKADALAADGVAAFATPAETVSDARVVVT 71
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L VL + G++ + ST+ ++ A L F DAPV G
Sbjct: 72 VLNDADGVLK---AMEAAAPKLAAGTIWVQVSTVGVRGIARLAAFARTHDLVFYDAPVQG 128
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHC---GQIGSGQVAKLTNNMLMGI 645
A+NA L +A G + D + PL +G + G G+G KL N
Sbjct: 129 SRQPAENAQLVVLAAGPESDRAQVQPLFDAIGRRTLWVADDGSTGAGSRLKLALNHYAFT 188
Query: 646 TGMATAECMNM 678
A AE + +
Sbjct: 189 LTHAIAESLKL 199
>UniRef50_Q97ZE5 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=4;
Sulfolobaceae|Rep: 3-hydroxyisobutyrate dehydrogenase -
Sulfolobus solfataricus
Length = 289
Score = 65.7 bits (153), Expect = 1e-09
Identities = 54/191 (28%), Positives = 81/191 (42%), Gaps = 2/191 (1%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ +GLG MG +AANL K YD +++ + + K N +
Sbjct: 3 IGLIGLGIMGYRIAANLAKANKLNLVYDRTQEKIESFVKE--YKVNGVQNTKDLVESSDV 60
Query: 295 ILTSNKVVLDVYLGKDGV--VAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
I+T ++ D Y K V + KG +LID STI P + + G DAPV
Sbjct: 61 IIT---MLADDYAVKSVVEPLIPLMKGKILIDMSTISPTLSISLAKRIESNGGTMFDAPV 117
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGIT 648
G + + L + GG K+ F+ + K + + G G G +KL NN+L+
Sbjct: 118 IGTSVFVEQKKLVVLVGGPKDKFDIVNDIAKETASLVVYMGPNGMGLYSKLVNNLLLASY 177
Query: 649 GMATAECMNMG 681
A AE N G
Sbjct: 178 VAAIAEAYNFG 188
>UniRef50_A4FKN9 Cluster: 2-hydroxy-3-oxopropionate reductase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
2-hydroxy-3-oxopropionate reductase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 297
Score = 64.9 bits (151), Expect = 2e-09
Identities = 51/189 (26%), Positives = 85/189 (44%), Gaps = 6/189 (3%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V +GLG MG +A L + G V S+ AAA+ GV + +
Sbjct: 5 VGVIGLGPMGANLALRLAEAGLDVVATSRSQGTREAAAREGVRVVDDVRALAGRLRAASP 64
Query: 295 ---ILTSNKVVLDVYLG-KDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 462
++ S V DG++A + +++D+ST P + + +G DA
Sbjct: 65 KPVVVVSLPSGPQVRAAVVDGLLADGGE-FVVVDTSTCAPADARSLADDLHARGCAVVDA 123
Query: 463 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLM- 639
PVSGG A+ +L+ M GG + D + +++ + CG G+GQ+AK N +++
Sbjct: 124 PVSGGPTAARAGSLSVMVGGTEADVAAADEVIRAFAGRVVVCGGPGAGQIAKACNQLVVT 183
Query: 640 -GITGMATA 663
GI +A A
Sbjct: 184 AGIAVVAEA 192
>UniRef50_Q21ZT0 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Rhodoferax ferrireducens T118|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Rhodoferax ferrireducens (strain DSM 15236 / ATCC
BAA-621 / T118)
Length = 315
Score = 64.5 bits (150), Expect = 2e-09
Identities = 46/178 (25%), Positives = 81/178 (45%), Gaps = 2/178 (1%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYD-PSKDALNAAAKNGV-TPANSIXXXXXXXX 282
+ + F+G+G MG +A NL+K+G + D P ++ K G T A
Sbjct: 5 RKLGFIGVGLMGHGLAKNLLKQGHAMTLLDHPGNQPIDDLMKMGAQTVATPKEVATAADV 64
Query: 283 XXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDA 462
+ S +V VY G DG++ + G +++D++T DP ++ +G + DA
Sbjct: 65 VFLCVNGSPQVEACVY-GADGLLEGLRAGGVVVDATTADPVSTLKVAAAVQARGGRYVDA 123
Query: 463 PVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNML 636
P++ A++ + M GG PL++ F G++GSG KL +N +
Sbjct: 124 PMTRTSQHAEDGCVNAMLGGDAVTIAEVRPLIEAYAENIFIGGEVGSGHRLKLLHNYI 181
>UniRef50_A1UDJ6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding precursor; n=7; Mycobacterium|Rep:
6-phosphogluconate dehydrogenase, NAD-binding precursor
- Mycobacterium sp. (strain KMS)
Length = 292
Score = 64.5 bits (150), Expect = 2e-09
Identities = 54/189 (28%), Positives = 78/189 (41%), Gaps = 1/189 (0%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
+ V +GLG MG +AA+L+ V +D D L + G A
Sbjct: 2 RRVGVIGLGGMGSALAASLLATDHYVVCFDIRPDVLRPIVELGAEAAADARELAGACDVV 61
Query: 289 XSILTSNKVVLDVYLGKD-GVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 465
+ L VL+V LG + GV+A G+ L+D ST +P V I G F D P
Sbjct: 62 LTFLPGPSQVLEVALGSERGVLAGLADGAALLDMSTCNPEVAAIIGQAYDAAGRRFVDCP 121
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 645
VS A N T+ + GG +L + +CG G+G KL N +
Sbjct: 122 VS---RKAPNMTV--LVGGPSGVLGPDADVLAAVSRTLVYCGHRGAGYATKLLNQHIKYS 176
Query: 646 TGMATAECM 672
+A+AE +
Sbjct: 177 WYLASAEAL 185
>UniRef50_Q3W031 Cluster: Putative dehydrogenase; n=1; Frankia sp.
EAN1pec|Rep: Putative dehydrogenase - Frankia sp.
EAN1pec
Length = 285
Score = 63.7 bits (148), Expect = 4e-09
Identities = 49/191 (25%), Positives = 79/191 (41%), Gaps = 2/191 (1%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
VAFLGLG MG MA +++ G + ++ + G + A
Sbjct: 3 VAFLGLGRMGVRMAHHILAAGHELAVWNRTPGRAGELTARGASEAADPAGAVRGADACVL 62
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L DV V+ A G L+I+ +T+ P ++ +AL GL + DAPV G
Sbjct: 63 MLFDPASAADVLA---AVIPAAPPGLLVINCTTVGPAAAREQGSVALAAGLRYLDAPVIG 119
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMG--AKQFHCGQIGSGQVAKLTNNMLMGIT 648
+ A+ TL + G D + +L+ G + H G +G+ K N+ +
Sbjct: 120 TIGPAEAGTLRVLVGAADADLAAARGILETFGDPGRIDHVGPVGAASALKTVFNLGLAEA 179
Query: 649 GMATAECMNMG 681
A AE + G
Sbjct: 180 TAAAAEVLRYG 190
>UniRef50_Q01PV6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Solibacter usitatus Ellin6076|Rep:
6-phosphogluconate dehydrogenase, NAD-binding -
Solibacter usitatus (strain Ellin6076)
Length = 267
Score = 62.9 bits (146), Expect = 7e-09
Identities = 49/185 (26%), Positives = 79/185 (42%)
Frame = +1
Query: 130 LGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXSILTSN 309
+G +G +A L G+TV GYD L + G A + L ++
Sbjct: 1 MGLLGSAIADRLSAAGYTVVGYD-----LIPERRRGADSAQEVIGKCQTTFLC---LPTS 52
Query: 310 KVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGA 489
VV V G V A G ++D +T +P + + G+ + DA V G
Sbjct: 53 DVVAQVI----GSVKPAA-GITMVDCTTGEPESMAAMGEKLAKSGVDYLDATVLGSSKVV 107
Query: 490 QNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAEC 669
++ MAGGR+E F+ + PL + ++ F+ G G+G KL N+ +G+ AE
Sbjct: 108 RSGAAVVMAGGRRESFDAASPLFRTFASRAFYLGPFGAGARMKLVVNLALGLHRAVLAET 167
Query: 670 MNMGH 684
+ H
Sbjct: 168 LAFAH 172
>UniRef50_A3ES45 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep:
3-hydroxyisobutyrate dehydrogenase - Leptospirillum sp.
Group II UBA
Length = 307
Score = 62.9 bits (146), Expect = 7e-09
Identities = 45/181 (24%), Positives = 78/181 (43%), Gaps = 2/181 (1%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXX 288
K ++G GNMG MA NL++ G + ++ + L K G +
Sbjct: 12 KEAVWIGTGNMGLPMAKNLLRSGIRLGVHNRTPQRLAPLLKAGAHAIADLRGSLSGTPLV 71
Query: 289 XSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPV 468
++L + V + L + G++ +G + + T+ P ++ E+G APV
Sbjct: 72 FTMLADDAAVKETVLKEGGLLDSLPQGGVHVSMGTLSPGFVLELSKTHTERGQILVSAPV 131
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGS--GQVAKLTNNMLMG 642
G A+ TL +A G ++ E LPLL+ +G+ F G+ S + L N L G
Sbjct: 132 FGRPDRAEAGTLTIVAAGPQKTLESLLPLLEHLGSPVFCVGEDPSLANHIKVLGNFTLAG 191
Query: 643 I 645
+
Sbjct: 192 L 192
>UniRef50_A7I8V1 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=1; Candidatus Methanoregula boonei
6A8|Rep: 6-phosphogluconate dehydrogenase, NAD-binding -
Methanoregula boonei (strain 6A8)
Length = 288
Score = 62.5 bits (145), Expect = 1e-08
Identities = 46/192 (23%), Positives = 85/192 (44%)
Frame = +1
Query: 106 DKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXX 285
++ V +GLG++G +A L+ +G V ++ + A+ GV A S
Sbjct: 4 EQTVGCIGLGHLGHTIARRLIDQGVPVAVWNRTP---KKASDLGVPVAASPRDLVGRVDV 60
Query: 286 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 465
L + V V G +G+++ G ++ID++T + A + G + + P
Sbjct: 61 VLINLFDSDAVESVLSGPEGLLSGPCTGKIIIDTTTNHFGRVSDFYAGARDHGATYLECP 120
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 645
V G V+ A L + G + +E PLL +G+ ++ G+ KL NN+++G
Sbjct: 121 VLGSVVPASQGKLTVLVSGDEGTYEVVKPLLSRIGSTLYYLGEPALATKMKLINNLVLGS 180
Query: 646 TGMATAECMNMG 681
AE + +G
Sbjct: 181 FMATCAEAVALG 192
>UniRef50_Q13VQ8 Cluster: Putative dehydrogenase/oxidoreductase
protein; n=2; Burkholderiales|Rep: Putative
dehydrogenase/oxidoreductase protein - Burkholderia
xenovorans (strain LB400)
Length = 300
Score = 62.1 bits (144), Expect = 1e-08
Identities = 44/189 (23%), Positives = 75/189 (39%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V +G+G +G +A+NL+ G+ V GY +++ A G ++
Sbjct: 9 VGIIGIGQLGSAIASNLLDMGYRVVGYRRNRNEAQAFVDAGGELVDTPSLVVQQADFIFL 68
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
L + V G G++ K G +++ T + G +A +SG
Sbjct: 69 CLPNESASNAVLEGVGGILPLLKDGKTVVEVGTYRKSFKLMQAEKIQATGANILEAELSG 128
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
F GG +E+ PLL+ + +F G G+ KL N L+ + +
Sbjct: 129 SPSLVLARKACFYVGGTDSVYEKCEPLLQAITDNRFFLGAFGTAVSMKLIANYLVTVNTL 188
Query: 655 ATAECMNMG 681
A AE MN+G
Sbjct: 189 AAAEAMNLG 197
>UniRef50_A3Q3U7 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Mycobacterium|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Mycobacterium sp. (strain
JLS)
Length = 279
Score = 62.1 bits (144), Expect = 1e-08
Identities = 50/189 (26%), Positives = 70/189 (37%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
V FLG G +G M L+ G V Y +DA G A+S+ S
Sbjct: 5 VGFLGAGQLGEPMVERLLGAGHDVLVYARREDARRRLEAKGAALADSVADLAHGSDVLIS 64
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
L S+ + + LG +G +A+AK ++ + S T G DAPVSG
Sbjct: 65 CLFSDAQLRETGLGPNGFIANAKPAAVFV-SHTTGTVATLTALRDHSSSGPVVLDAPVSG 123
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGM 654
TL + GG + P+L G +GS KL NN+L
Sbjct: 124 TADDIAAGTLTVLLGGPADAVAAVTPVLAAYADPLVPTGTLGSALALKLINNLLFAANAQ 183
Query: 655 ATAECMNMG 681
A +G
Sbjct: 184 LLAAATELG 192
>UniRef50_A5CN67 Cluster: Putative beta-hydroxyacid dehydrogenase;
n=1; Clavibacter michiganensis subsp. michiganensis
NCPPB 382|Rep: Putative beta-hydroxyacid dehydrogenase -
Clavibacter michiganensis subsp. michiganensis (strain
NCPPB 382)
Length = 291
Score = 61.7 bits (143), Expect = 2e-08
Identities = 46/189 (24%), Positives = 81/189 (42%), Gaps = 1/189 (0%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ LG G MG M+ ++++ G + ++ S + A G T A S
Sbjct: 1 MTLLGTGVMGSGMSRSILRAGLPLTVWNRSAEKAAPLADAGATVAESAADAVRDADVVVV 60
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
+L VL+V V + G++++ SST+ ++I +A E + F DAPV G
Sbjct: 61 MLFDADAVLEVLAE---VAPALRPGAVVLQSSTVGVEGTRRIAALAAEHAVRFVDAPVLG 117
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCG-QIGSGQVAKLTNNMLMGITG 651
A+ L + G ++D + P+L+ G++ G G G KL N +
Sbjct: 118 TRGPAEQGLLVHLVSGSEDDLAVARPVLEATGSRTVVAGSDAGPGSALKLACNAWIASIT 177
Query: 652 MATAECMNM 678
AT + + +
Sbjct: 178 AATGQSLGL 186
>UniRef50_Q19TN0 Cluster: 3-hydroxyisobutyrate dehydrogenase family
protein; n=11; Francisella tularensis|Rep:
3-hydroxyisobutyrate dehydrogenase family protein -
Francisella tularensis subsp. mediasiatica
Length = 295
Score = 61.3 bits (142), Expect = 2e-08
Identities = 45/200 (22%), Positives = 84/200 (42%), Gaps = 1/200 (0%)
Frame = +1
Query: 109 KNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNG-VTPANSIXXXXXXXXX 285
K V +GLGNMG + +L+ G+ + ++ +K +N V +S
Sbjct: 6 KQVGIIGLGNMGSVVIDHLLTSGYEIFIHNRTKAKAEKWLRNTQVVWCDSPKELAENCEI 65
Query: 286 XXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAP 465
L ++ +VYL K+G+ + ++D+ST+ + +Q+ + + D P
Sbjct: 66 IICCLYNDIAAKNVYLSKNGLTSINLVNHTILDASTLSVSCFEQLNKVVTQNNGKLIDMP 125
Query: 466 VSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGI 645
+SG Q M G +E+ + + L+ + K + GS KL N ++
Sbjct: 126 ISGNPAALQEKRALIMLGATEEECKSFVHFLEALSNKILYLDIAGSALKEKLCINEMLFT 185
Query: 646 TGMATAECMNMGH*NGTRTE 705
+ E M + NG +TE
Sbjct: 186 QWFSYCEAMLLAENNGIKTE 205
>UniRef50_Q0W2D7 Cluster: Putative 6-phosphogluconate dehydrogenase;
n=1; uncultured methanogenic archaeon RC-I|Rep: Putative
6-phosphogluconate dehydrogenase - Uncultured
methanogenic archaeon RC-I
Length = 310
Score = 61.3 bits (142), Expect = 2e-08
Identities = 51/176 (28%), Positives = 80/176 (45%), Gaps = 4/176 (2%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ +GLG MGG +A V+KG V + SK + A G+ A++
Sbjct: 3 LGIIGLGRMGGSLALQAVEKGVEVVAH--SKHSHPDFATRGIHIADTYEEFARLLRTPRI 60
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLID--SSTIDPNVPKQIFPIALEKGLGFTDAPV 468
I S + + ++ H ++G +L+D +S +V ++ +KG D
Sbjct: 61 IYLSLPAGQIIDQVIESLIPHLERGDVLMDGGNSFFRDSVARE--EALRKKGFRLLDCGT 118
Query: 469 SGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAK--QFHCGQIGSGQVAKLTNN 630
SGGV GA+ FM GG +E FE + P+LK + + G GSG AKL +N
Sbjct: 119 SGGVDGARTGA-CFMVGGSREGFELAEPVLKKLAVDGGVLYTGSPGSGHYAKLVHN 173
>UniRef50_Q21AH6 Cluster: 6-phosphogluconate dehydrogenase,
NAD-binding; n=3; Bacteria|Rep: 6-phosphogluconate
dehydrogenase, NAD-binding - Rhodopseudomonas palustris
(strain BisB18)
Length = 292
Score = 60.9 bits (141), Expect = 3e-08
Identities = 47/188 (25%), Positives = 80/188 (42%), Gaps = 1/188 (0%)
Frame = +1
Query: 97 SNTDKNVAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXX 276
S + N+ +GLG MGG +A L +++ YD SK A+ +G + A S
Sbjct: 2 SRSIDNIGIIGLGAMGGAVATRLTSGPWSLAVYDLSKAAIERLVSHGASAAASARDAVAG 61
Query: 277 XXXXXSILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLG-F 453
S L + V + A +G++ +D STIDP +++ + + G F
Sbjct: 62 RAVVFSCLPTPDHVEAFWTEH---AADLAEGAIAVDLSTIDPATSRRVSDMIAKGGRARF 118
Query: 454 TDAPVSGGVMGAQNATLAFMAGGRKEDFERSLPLLKVMGAKQFHCGQIGSGQVAKLTNNM 633
+ A+ + GG + E P+ K M + F G + + KL +N
Sbjct: 119 VACTMGKTPAMAEKGEIPLFVGGDQVSLEALAPVFKHMSSVVFDMGSVEGATMFKLISN- 177
Query: 634 LMGITGMA 657
L+G+T +A
Sbjct: 178 LVGMTNLA 185
>UniRef50_Q0SAG5 Cluster: Phosphogluconate dehydrogenase; n=23;
Actinobacteria (class)|Rep: Phosphogluconate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 303
Score = 60.1 bits (139), Expect = 5e-08
Identities = 49/178 (27%), Positives = 75/178 (42%), Gaps = 6/178 (3%)
Frame = +1
Query: 115 VAFLGLGNMGGFMAANLVKKGFTVRGYDPSKDALNAAAKNGVTPANSIXXXXXXXXXXXS 294
+ +GLG MG M L G V GYDP D + A+ +
Sbjct: 3 IGLVGLGKMGFNMRERLRAHGHEVVGYDPRPDVTDVAS------LAELARRLESPRVVWV 56
Query: 295 ILTSNKVVLDVYLGKDGVVAHAKKGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSG 474
++ + K+ D V+ + G L+ID K + +G+G+ D VSG
Sbjct: 57 MVPAGKITQDTVTELSSVL---ETGDLVIDGGNSRYTDDKVHGELLGSRGIGYLDCGVSG 113
Query: 475 GVMGAQNATLAFMAGGRKEDFERSLPL---LKVMGAKQ---FHCGQIGSGQVAKLTNN 630
GV G ++ M GG D ER+LP+ L+ G + H G +G+G AK+ +N
Sbjct: 114 GVWGLEDG-YGMMVGGSDADVERALPIFDALRPEGERADGFVHAGPVGAGHYAKMIHN 170
>UniRef50_Q8U2W2 Cluster: 3-hydroxyisobutyrate dehydrogenase; n=17;
Pyrococcus|Rep: 3-hydroxyisobutyrate dehydrogenase -
Pyrococcus furiosus
Length = 278
Score = 60.1 bits (139), Expect = 5e-08
Identities = 32/114 (28%), Positives = 55/114 (48%)
Frame = +1
Query: 364 KGSLLIDSSTIDPNVPKQIFPIALEKGLGFTDAPVSGGVMGAQNATLAFMAGGRKEDFER 543
+G +++D++T + I G + ++PV G V+ A+N L + G +E FER
Sbjct: 77 RGKIIVDTTTNHHEKVLEFHEIYRNVGAFYLESPVIGSVIPARNGQLTILVSGEREAFER 136
Query: 544 SLPLLKVMGAKQFHCGQIGSGQVAKLTNNMLMGITGMATAECMNMGH*NGTRTE 705
P L+ +G + F+ + G KL NN ++G A E + +G G E
Sbjct: 137 VRPYLQKLGKRIFYFNEPGKATKLKLINNFVLGAFMAALGEAIALGEKAGLSRE 190
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 796,005,273
Number of Sequences: 1657284
Number of extensions: 17792217
Number of successful extensions: 52640
Number of sequences better than 10.0: 373
Number of HSP's better than 10.0 without gapping: 50043
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 52418
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 57024798702
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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