BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= maV30125 (671 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q1G151 Cluster: Putative alcohol dehydrogenase; n=1; Bo... 175 1e-42 UniRef50_Q6RUR3 Cluster: Putative alcohol dehydrogenase; n=2; Ne... 157 2e-37 UniRef50_Q6NYE8 Cluster: Zgc:56585 protein; n=5; Clupeocephala|R... 153 3e-36 UniRef50_UPI0000DB7440 Cluster: PREDICTED: similar to 15-hydroxy... 149 8e-35 UniRef50_UPI00015B5316 Cluster: PREDICTED: similar to putative a... 142 9e-33 UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative a... 142 9e-33 UniRef50_UPI00015B4C63 Cluster: PREDICTED: similar to putative a... 139 5e-32 UniRef50_UPI0000513348 Cluster: PREDICTED: similar to 15-hydroxy... 139 6e-32 UniRef50_UPI00015B573D Cluster: PREDICTED: similar to putative a... 136 3e-31 UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative a... 132 1e-29 UniRef50_UPI00015B42E2 Cluster: PREDICTED: similar to putative a... 131 1e-29 UniRef50_UPI000051334A Cluster: PREDICTED: similar to 15-hydroxy... 128 1e-28 UniRef50_UPI00015B5A58 Cluster: PREDICTED: similar to putative a... 127 3e-28 UniRef50_UPI0000D57364 Cluster: PREDICTED: similar to 15-hydroxy... 126 5e-28 UniRef50_UPI00015B5FC8 Cluster: PREDICTED: similar to putative a... 125 9e-28 UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|R... 125 1e-27 UniRef50_Q1HPX6 Cluster: Alcohol dehydrogenase; n=1; Bombyx mori... 124 2e-27 UniRef50_P15428 Cluster: 15-hydroxyprostaglandin dehydrogenase [... 122 1e-26 UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative a... 121 1e-26 UniRef50_UPI0000E47587 Cluster: PREDICTED: similar to 15-hydroxy... 121 1e-26 UniRef50_Q7PY55 Cluster: ENSANGP00000013280; n=4; Endopterygota|... 119 6e-26 UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to hydroxypro... 119 7e-26 UniRef50_UPI0000D57365 Cluster: PREDICTED: similar to CG4899-PA,... 114 2e-24 UniRef50_UPI00015B572C Cluster: PREDICTED: similar to putative a... 108 1e-22 UniRef50_Q9I7R3 Cluster: CG18814-PA; n=3; Sophophora|Rep: CG1881... 103 3e-21 UniRef50_UPI0000D5767E Cluster: PREDICTED: similar to 15-hydroxy... 102 7e-21 UniRef50_Q5P8S6 Cluster: Putative dehydrogenase; n=4; Proteobact... 99 1e-19 UniRef50_A6YPS8 Cluster: Oxidoreductase; n=1; Triatoma infestans... 96 8e-19 UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR... 95 1e-18 UniRef50_Q9NAR7 Cluster: Alcohol dehydrogenase; n=23; Schizophor... 95 1e-18 UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1; ... 93 4e-18 UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella ve... 93 4e-18 UniRef50_Q9ABI1 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 93 7e-18 UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase fam... 91 2e-17 UniRef50_Q6C6W8 Cluster: Similar to tr|Q9WYD3 Thermotoga maritim... 91 2e-17 UniRef50_Q5TWK5 Cluster: ENSANGP00000025423; n=1; Anopheles gamb... 89 7e-17 UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR... 89 9e-17 UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: O... 89 1e-16 UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain dehydrogena... 88 2e-16 UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 88 2e-16 UniRef50_Q89M15 Cluster: Dehydrogenase; n=3; Proteobacteria|Rep:... 87 3e-16 UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR... 87 3e-16 UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reducta... 87 4e-16 UniRef50_Q2W431 Cluster: Dehydrogenase with different specificit... 87 4e-16 UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillu... 87 5e-16 UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 86 6e-16 UniRef50_Q6XPZ7 Cluster: Short-chain dehydrogenase/reductase; n=... 86 8e-16 UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase b... 85 1e-15 UniRef50_P91615 Cluster: Alcohol dehydrogenase-related 31 kDa pr... 85 1e-15 UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR... 85 2e-15 UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR... 85 2e-15 UniRef50_Q89KQ8 Cluster: Blr4846 protein; n=2; Proteobacteria|Re... 83 4e-15 UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR... 83 4e-15 UniRef50_P00334 Cluster: Alcohol dehydrogenase; n=485; Drosophil... 83 4e-15 UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 83 8e-15 UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1; Psychro... 83 8e-15 UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR... 83 8e-15 UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR... 83 8e-15 UniRef50_P54398 Cluster: Fat body protein 2; n=6; Schizophora|Re... 83 8e-15 UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain dehydrogena... 82 1e-14 UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyc... 82 1e-14 UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3; Bacill... 82 1e-14 UniRef50_Q6UWP2 Cluster: Dehydrogenase/reductase SDR family memb... 82 1e-14 UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR... 81 2e-14 UniRef50_Q28GY1 Cluster: Novel protein containing short chain de... 81 2e-14 UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogena... 81 2e-14 UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;... 81 3e-14 UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 80 4e-14 UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR... 80 4e-14 UniRef50_Q8YQR6 Cluster: All3753 protein; n=6; Bacteria|Rep: All... 80 6e-14 UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2; Actinom... 80 6e-14 UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR... 80 6e-14 UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;... 80 6e-14 UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4; Brucel... 79 7e-14 UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep... 79 7e-14 UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacte... 79 7e-14 UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 79 1e-13 UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductas... 79 1e-13 UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_A1IFS9 Cluster: Short chain dehydrogenase family protei... 79 1e-13 UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 79 1e-13 UniRef50_P19871 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=... 79 1e-13 UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular ... 79 1e-13 UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SD... 79 1e-13 UniRef50_Q399N8 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 79 1e-13 UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammapr... 79 1e-13 UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20; ... 78 2e-13 UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_A1UMZ0 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_Q22CU9 Cluster: Oxidoreductase, short chain dehydrogena... 78 2e-13 UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 78 2e-13 UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogena... 78 2e-13 UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Li... 77 3e-13 UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 77 3e-13 UniRef50_Q82FK0 Cluster: Putative dehydrogenase; n=2; Streptomyc... 77 3e-13 UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2; Bacteri... 77 3e-13 UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 77 3e-13 UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Sho... 77 3e-13 UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR... 77 3e-13 UniRef50_A0HI81 Cluster: Short-chain dehydrogenase/reductase SDR... 77 3e-13 UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019;... 77 3e-13 UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 77 4e-13 UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_Q15Q07 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=... 77 4e-13 UniRef50_Q71R50 Cluster: Dehydrogenase/reductase SDR family memb... 77 4e-13 UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 77 5e-13 UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase... 77 5e-13 UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8;... 77 5e-13 UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13 UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Re... 77 5e-13 UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain dehydrogena... 76 7e-13 UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR... 76 7e-13 UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR... 76 7e-13 UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR... 76 7e-13 UniRef50_Q97EW4 Cluster: Predicted short-chain dehydrogenase; n=... 76 9e-13 UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 76 9e-13 UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain dehydrogena... 76 9e-13 UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reducta... 76 9e-13 UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR... 76 9e-13 UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR... 76 9e-13 UniRef50_O86553 Cluster: Putative dehydrogenase; n=1; Streptomyc... 76 9e-13 UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase, puta... 76 9e-13 UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-car... 75 1e-12 UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4; Legion... 75 1e-12 UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=... 75 1e-12 UniRef50_A0X2J5 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_Q9FX95 Cluster: ARP protein; n=8; Magnoliophyta|Rep: AR... 75 1e-12 UniRef50_UPI0000E465C5 Cluster: PREDICTED: similar to MGC80593 p... 75 2e-12 UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -... 75 2e-12 UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 75 2e-12 UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 75 2e-12 UniRef50_Q2JG54 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_Q1IPJ3 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 75 2e-12 UniRef50_A6UZF9 Cluster: Oxidoreductase, short chain dehydrogena... 75 2e-12 UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protei... 75 2e-12 UniRef50_A1BFL6 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_A0VFC2 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_A0LZZ5 Cluster: Short-chain dehydrogenase/reductase fam... 75 2e-12 UniRef50_Q2UEK6 Cluster: Dehydrogenases with different specifici... 75 2e-12 UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 75 2e-12 UniRef50_P66778 Cluster: Probable oxidoreductase ephD; n=16; Myc... 75 2e-12 UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 75 2e-12 UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1... 75 2e-12 UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_Q0GL61 Cluster: Short-chain dehydrogenase; n=3; Lactoba... 75 2e-12 UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x;... 75 2e-12 UniRef50_A5BP77 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12 UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;... 75 2e-12 UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR... 74 3e-12 UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR... 74 3e-12 UniRef50_A6CTS3 Cluster: Putative uncharacterized protein; n=1; ... 74 3e-12 UniRef50_A4XF64 Cluster: Short-chain dehydrogenase/reductase SDR... 74 3e-12 UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1; ... 74 3e-12 UniRef50_Q2U0U8 Cluster: Dehydrogenases with different specifici... 74 3e-12 UniRef50_Q5UYC2 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 74 3e-12 UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 74 3e-12 UniRef50_Q7M9W0 Cluster: 3-OXOACYL-REDUCTASE; n=24; Epsilonprote... 74 4e-12 UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chai... 74 4e-12 UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacill... 74 4e-12 UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 74 4e-12 UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like ... 74 4e-12 UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR... 74 4e-12 UniRef50_A2U319 Cluster: Short-chain dehydrogenase/reductase SDR... 74 4e-12 UniRef50_UPI00015B4F48 Cluster: PREDICTED: similar to ENSANGP000... 73 5e-12 UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 73 5e-12 UniRef50_Q3IVD0 Cluster: Short-chain alcohol dehydrogenases; n=2... 73 5e-12 UniRef50_Q3VZL7 Cluster: Short-chain dehydrogenase/reductase SDR... 73 5e-12 UniRef50_Q03X86 Cluster: Putative uncharacterized protein; n=1; ... 73 5e-12 UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5; Proteob... 73 5e-12 UniRef50_Q8FA17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 73 6e-12 UniRef50_Q0VL04 Cluster: Oxidoreductase, putative; n=1; Alcanivo... 73 6e-12 UniRef50_Q0S5L2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 73 6e-12 UniRef50_A7IMM1 Cluster: Short-chain dehydrogenase/reductase SDR... 73 6e-12 UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain dehydrogena... 73 6e-12 UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR... 73 6e-12 UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627;... 73 6e-12 UniRef50_P50197 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 73 6e-12 UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60; Bacteria|... 73 6e-12 UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oc... 73 8e-12 UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular o... 73 8e-12 UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase prec... 73 8e-12 UniRef50_O33454 Cluster: P-cumic alcohol dehydrogenase; n=3; Pro... 73 8e-12 UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR... 73 8e-12 UniRef50_Q0D3V4 Cluster: Os07g0664000 protein; n=34; cellular or... 73 8e-12 UniRef50_Q9VU92 Cluster: CG8757-PA; n=3; Drosophila melanogaster... 73 8e-12 UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_Q13H99 Cluster: Putative short-chain dehydrogenase/redu... 72 1e-11 UniRef50_Q0M0K7 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_Q54D03 Cluster: Putative uncharacterized protein; n=1; ... 72 1e-11 UniRef50_Q22RI1 Cluster: Oxidoreductase, short chain dehydrogena... 72 1e-11 UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh... 72 1e-11 UniRef50_UPI00015B572E Cluster: PREDICTED: similar to putative a... 72 1e-11 UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 72 1e-11 UniRef50_Q5LMX2 Cluster: 20-beta-hydroxysteroid dehydrogenase, p... 72 1e-11 UniRef50_Q11ZZ1 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A6W2S3 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A4TBK3 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A7S4C5 Cluster: Predicted protein; n=1; Nematostella ve... 72 1e-11 UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular organisms... 72 1e-11 UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=... 72 1e-11 UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34; Proteo... 72 1e-11 UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59; cell... 72 1e-11 UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3; Clo... 72 1e-11 UniRef50_Q89UC3 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 71 2e-11 UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=... 71 2e-11 UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11 UniRef50_A5WHV5 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11 UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11 UniRef50_A4ALI9 Cluster: Putative short chain dehydrogenase; n=2... 71 2e-11 UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bac... 71 2e-11 UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain dehydrogena... 71 2e-11 UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11 UniRef50_A0Z215 Cluster: Short chain dehydrogenase; n=2; Gammapr... 71 2e-11 UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11 UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family memb... 71 2e-11 UniRef50_P39071 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate dehyd... 71 2e-11 UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|R... 71 3e-11 UniRef50_A6VY27 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11 UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte... 71 3e-11 UniRef50_A0PSR4 Cluster: Short-chain dehydrogenase; n=1; Mycobac... 71 3e-11 UniRef50_Q6NNV7 Cluster: RH03309p; n=4; melanogaster subgroup|Re... 71 3e-11 UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 71 3e-11 UniRef50_Q62E12 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 71 3e-11 UniRef50_Q2S7V4 Cluster: Short-chain alcohol dehydrogenase-like ... 71 3e-11 UniRef50_Q3EU48 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 71 3e-11 UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11 UniRef50_A4T9G9 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11 UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogena... 71 3e-11 UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogena... 71 3e-11 UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11 UniRef50_Q2FSZ0 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11 UniRef50_Q48I17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 70 4e-11 UniRef50_Q02AD5 Cluster: Short-chain dehydrogenase/reductase SDR... 70 4e-11 UniRef50_A5V545 Cluster: Short-chain dehydrogenase/reductase SDR... 70 4e-11 UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR... 70 4e-11 UniRef50_A1UAJ6 Cluster: Acetoin reductases; n=18; Bacteria|Rep:... 70 4e-11 UniRef50_Q965D6 Cluster: 3-oxoacyl-acyl-carrier protein reductas... 70 4e-11 UniRef50_O15744 Cluster: PksB; n=2; Dictyostelium discoideum|Rep... 70 4e-11 UniRef50_Q9C826 Cluster: Xanthoxin dehydrogenase; n=41; Magnolio... 70 4e-11 UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia succinici... 70 6e-11 UniRef50_Q54472 Cluster: Oxido-reductase; n=3; Bacteria|Rep: Oxi... 70 6e-11 UniRef50_Q11E37 Cluster: Short-chain dehydrogenase/reductase SDR... 70 6e-11 UniRef50_A6BFV0 Cluster: Putative uncharacterized protein; n=1; ... 70 6e-11 UniRef50_A4M6M0 Cluster: Short-chain dehydrogenase/reductase SDR... 70 6e-11 UniRef50_A4B8L3 Cluster: Short chain dehydrogenase; n=1; Alterom... 70 6e-11 UniRef50_A3JFT9 Cluster: Short chain dehydrogenase; n=1; Marinob... 70 6e-11 UniRef50_A3IK59 Cluster: Oxidoreductase, short chain dehydrogena... 70 6e-11 UniRef50_A0Z7K1 Cluster: Short-chain dehydrogenase/reductase SDR... 70 6e-11 UniRef50_A7EQI6 Cluster: Putative uncharacterized protein; n=1; ... 70 6e-11 UniRef50_Q92EK7 Cluster: Uncharacterized oxidoreductase Lin0452;... 70 6e-11 UniRef50_Q8EQ60 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 69 8e-11 UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogena... 69 8e-11 UniRef50_Q7NCW8 Cluster: Gll2858 protein; n=6; Bacteria|Rep: Gll... 69 8e-11 UniRef50_Q39TR6 Cluster: Short-chain dehydrogenase/reductase SDR... 69 8e-11 UniRef50_Q0SC53 Cluster: Dehydrogenase; n=3; Corynebacterineae|R... 69 8e-11 UniRef50_A6LUV1 Cluster: Short-chain dehydrogenase/reductase SDR... 69 8e-11 UniRef50_A6EZZ8 Cluster: Short chain dehydrogenase; n=1; Marinob... 69 8e-11 UniRef50_Q0D3U7 Cluster: Os07g0665000 protein; n=18; Poales|Rep:... 69 8e-11 UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellula... 69 8e-11 UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 69 8e-11 UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 69 1e-10 UniRef50_Q8CNF1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 69 1e-10 UniRef50_Q88SD1 Cluster: Short-chain dehydrogenase/oxidoreductas... 69 1e-10 UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 69 1e-10 UniRef50_Q70I08 Cluster: Putative ketoreductase; n=1; Streptomyc... 69 1e-10 UniRef50_Q1VWP8 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_Q1V2H3 Cluster: Short chain dehydrogenase; n=2; Candida... 69 1e-10 UniRef50_Q1IP02 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_Q0B2G1 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_A7AZH2 Cluster: Putative uncharacterized protein; n=1; ... 69 1e-10 UniRef50_A6EGH2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 69 1e-10 UniRef50_A3XPR1 Cluster: Cyclohexanol dehydrogenase; n=1; Leeuwe... 69 1e-10 UniRef50_A1UEP6 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_UPI0000DB6B86 Cluster: PREDICTED: similar to CG9360-PA;... 69 1e-10 UniRef50_UPI0000518CA5 Cluster: PREDICTED: similar to antdh CG13... 69 1e-10 UniRef50_Q8YLL2 Cluster: Alr5286 protein; n=10; Cyanobacteria|Re... 69 1e-10 UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase pre... 69 1e-10 UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_Q26DV9 Cluster: Short-chain dehydrogenases/reductases f... 69 1e-10 UniRef50_Q1DDT9 Cluster: Oxidoreductase, short chain dehydrogena... 69 1e-10 UniRef50_Q12G63 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_Q07KD0 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_A4BGV8 Cluster: Short chain dehydrogenase; n=1; Reineke... 69 1e-10 UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_Q7SI45 Cluster: Putative uncharacterized protein NCU006... 69 1e-10 UniRef50_A2QS57 Cluster: Contig An08c0220, complete genome; n=2;... 69 1e-10 UniRef50_P19992 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh... 69 1e-10 UniRef50_Q56840 Cluster: 2-(R)-hydroxypropyl-CoM dehydrogenase; ... 69 1e-10 UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2; Streptomyc... 68 2e-10 UniRef50_Q988B7 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 68 2e-10 UniRef50_Q8EPA2 Cluster: Hypothetical conserved protein; n=1; Oc... 68 2e-10 UniRef50_Q890G1 Cluster: Short-chain dehydrogenase/oxidoreductas... 68 2e-10 UniRef50_Q390G9 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_Q3W0V5 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_Q1DCG1 Cluster: Oxidoreductase, short-chain dehydrogena... 68 2e-10 UniRef50_Q0RTV0 Cluster: Short-chain dehydrogenase, SDR family; ... 68 2e-10 UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 68 2e-10 UniRef50_A1ZK52 Cluster: Dehydrogenase/reductase SDR family memb... 68 2e-10 UniRef50_A0M3M9 Cluster: Short-chain dehydrogenase/reductase fam... 68 2e-10 UniRef50_UPI000050F9D4 Cluster: COG1028: Dehydrogenases with dif... 68 2e-10 UniRef50_Q9ABX6 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 68 2e-10 UniRef50_Q8KKW9 Cluster: Putative oxidoreductase protein; n=1; R... 68 2e-10 UniRef50_Q5NM60 Cluster: Short-chain alcohol dehydrogenase; n=14... 68 2e-10 UniRef50_Q55922 Cluster: Slr0315 protein; n=2; Bacteria|Rep: Slr... 68 2e-10 UniRef50_Q3IKU0 Cluster: Putative 3-oxoacyl-[acyl-carrier protei... 68 2e-10 UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_Q1YZB6 Cluster: Short chain dehydrogenase; n=6; Gammapr... 68 2e-10 UniRef50_Q1NCX9 Cluster: Putative uncharacterized protein; n=1; ... 68 2e-10 UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_Q13GX3 Cluster: Putative short-chain dehydrogenase/redu... 68 2e-10 UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A6T789 Cluster: Putative short-chain dehydrogenase/redu... 68 2e-10 UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 68 2e-10 UniRef50_A3I6G4 Cluster: Putative 7-alpha-hydroxysteroid dehydro... 68 2e-10 UniRef50_A1U9L1 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A0PSE4 Cluster: Short-chain type dehydrogenase; n=12; C... 68 2e-10 UniRef50_A0G4K1 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A0FY63 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_Q2UV13 Cluster: Reductases with broad range of substrat... 68 2e-10 UniRef50_P40747 Cluster: Uncharacterized oxidoreductase yuxG; n=... 68 2e-10 UniRef50_Q833Z8 Cluster: Short chain dehydrogenase; n=23; Bacill... 67 3e-10 UniRef50_Q81WX9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 67 3e-10 UniRef50_Q7UJY8 Cluster: Probable short-chain dehydrogenase; n=1... 67 3e-10 UniRef50_Q62GZ1 Cluster: Oxidoreductase, short chain dehydrogena... 67 3e-10 UniRef50_Q2IEG2 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_Q12QC5 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_A4QHZ4 Cluster: Putative uncharacterized protein; n=1; ... 67 3e-10 UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_A0KYX3 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_A0JVB1 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1;... 67 3e-10 UniRef50_UPI00015B5DCD Cluster: PREDICTED: similar to oxidoreduc... 67 4e-10 UniRef50_Q829D6 Cluster: Putative dehydrogenase; n=2; Streptomyc... 67 4e-10 UniRef50_Q7W386 Cluster: Short chain dehydrogenase; n=111; cellu... 67 4e-10 UniRef50_Q6N3Z0 Cluster: Putative short-chain dehydrogenase/redu... 67 4e-10 UniRef50_Q62E13 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 67 4e-10 UniRef50_Q62CL0 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 67 4e-10 UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxid... 67 4e-10 UniRef50_Q39TI0 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10 UniRef50_Q2SKD5 Cluster: Short-chain dehydrogenase of various su... 67 4e-10 UniRef50_Q2AGJ3 Cluster: NAD-dependent epimerase/dehydratase:Sho... 67 4e-10 UniRef50_A6WBU5 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10 UniRef50_A6W2Z2 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10 UniRef50_A6GFU2 Cluster: Short chain dehydrogenase; n=1; Plesioc... 67 4e-10 UniRef50_A4TAB8 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10 UniRef50_Q4J9S4 Cluster: Glucose 1-dehydrogenase; n=6; Thermopro... 67 4e-10 UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10 UniRef50_P54554 Cluster: Uncharacterized oxidoreductase yqjQ; n=... 67 4e-10 UniRef50_UPI00015B452D Cluster: PREDICTED: similar to ENSANGP000... 66 6e-10 UniRef50_UPI0000DB6BA4 Cluster: PREDICTED: similar to 3-hydroxya... 66 6e-10 UniRef50_Q988J7 Cluster: Oxidoreductase, short chain dehydrogena... 66 6e-10 UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specifici... 66 6e-10 UniRef50_Q87GW0 Cluster: Acetoacetyl-CoA reductase; n=7; Vibrio|... 66 6e-10 UniRef50_Q7VXT8 Cluster: Probable short-chain dehydrogenase; n=3... 66 6e-10 UniRef50_Q9S3U5 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 66 6e-10 UniRef50_Q84EX5 Cluster: R-specific alcohol dehydrogenase; n=5; ... 66 6e-10 UniRef50_Q3S8D5 Cluster: Putative short-chain dehydrogenase/redu... 66 6e-10 UniRef50_Q1ZIL9 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 66 6e-10 UniRef50_Q1YQ07 Cluster: Putative uncharacterized protein; n=1; ... 66 6e-10 UniRef50_Q1YPA9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 66 6e-10 UniRef50_Q081K4 Cluster: Short-chain dehydrogenase/reductase SDR... 66 6e-10 UniRef50_A7A2R8 Cluster: Putative uncharacterized protein; n=1; ... 66 6e-10 UniRef50_A5GRS5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 66 6e-10 UniRef50_A4AQP7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 66 6e-10 UniRef50_A1ZGN7 Cluster: Short-chain dehydrogenase/reductase SDR... 66 6e-10 UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR... 66 6e-10 UniRef50_A0YCW9 Cluster: Putative 3-oxoacyl-acyl carrier protein... 66 6e-10 UniRef50_P46331 Cluster: Uncharacterized oxidoreductase yxbG; n=... 66 6e-10 UniRef50_A4XEV7 Cluster: Short-chain dehydrogenase/reductase SDR... 44 6e-10 UniRef50_UPI000023F0AD Cluster: hypothetical protein FG09028.1; ... 66 7e-10 UniRef50_UPI000023CB88 Cluster: hypothetical protein FG04599.1; ... 66 7e-10 UniRef50_Q930L5 Cluster: Putative; n=3; Proteobacteria|Rep: Puta... 66 7e-10 UniRef50_Q92A39 Cluster: Lin2083 protein; n=16; Bacilli|Rep: Lin... 66 7e-10 UniRef50_Q8UHH7 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 66 7e-10 UniRef50_Q65F37 Cluster: Putative uncharacterized protein; n=1; ... 66 7e-10 UniRef50_Q2RUY0 Cluster: Short-chain dehydrogenase/reductase SDR... 66 7e-10 UniRef50_Q93QG5 Cluster: Cyclohexanol dehydrogenase; n=4; Bacter... 66 7e-10 UniRef50_Q5KRC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 66 7e-10 UniRef50_Q13HC1 Cluster: Putative short-chain dehydrogenase/redu... 66 7e-10 UniRef50_Q11BT8 Cluster: Short-chain dehydrogenase/reductase SDR... 66 7e-10 UniRef50_Q0TM71 Cluster: Oxidoreductase, short chain dehydrogena... 66 7e-10 UniRef50_Q0S4U3 Cluster: Dehydrogenase; n=2; Actinomycetales|Rep... 66 7e-10 UniRef50_A6X7S0 Cluster: Short-chain dehydrogenase/reductase SDR... 66 7e-10 UniRef50_A6W9N2 Cluster: Short-chain dehydrogenase/reductase SDR... 66 7e-10 UniRef50_A4ABL9 Cluster: Short-chain dehydrogenase/reductase SDR... 66 7e-10 UniRef50_A3ET57 Cluster: Short-chain alcohol dehydrogenase; n=2;... 66 7e-10 UniRef50_A0JVX6 Cluster: Short-chain dehydrogenase/reductase SDR... 66 7e-10 UniRef50_Q9VYU9 Cluster: CG9360-PA; n=12; Diptera|Rep: CG9360-PA... 66 7e-10 UniRef50_Q7Q3Q2 Cluster: ENSANGP00000007118; n=1; Anopheles gamb... 66 7e-10 UniRef50_Q16Q07 Cluster: Alcohol dehydrogenase, putative; n=1; A... 66 7e-10 UniRef50_Q0U1A7 Cluster: Putative uncharacterized protein; n=1; ... 66 7e-10 UniRef50_Q9Y394 Cluster: Dehydrogenase/reductase SDR family memb... 66 7e-10 UniRef50_Q8UAB0 Cluster: Dehydrogenase; n=1; Agrobacterium tumef... 66 1e-09 UniRef50_Q89WX4 Cluster: Short-chain dehydrogenase; n=11; Bradyr... 66 1e-09 UniRef50_Q88T73 Cluster: Short-chain dehydrogenase/oxidoreductas... 66 1e-09 UniRef50_Q65SP1 Cluster: FabG protein; n=10; Bacteria|Rep: FabG ... 66 1e-09 UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR... 66 1e-09 UniRef50_Q140J4 Cluster: Putative 3-oxoacyl-(Acyl-carrier protei... 66 1e-09 UniRef50_Q0FWE6 Cluster: Putative oxidoreductase; n=1; Roseovari... 66 1e-09 UniRef50_A7IJ54 Cluster: Short-chain dehydrogenase/reductase SDR... 66 1e-09 UniRef50_A6C1M0 Cluster: Short chain dehydrogenase; n=1; Plancto... 66 1e-09 UniRef50_A1K1F4 Cluster: Short-chain dehydrogenase family protei... 66 1e-09 UniRef50_A0UZI2 Cluster: Short-chain dehydrogenase/reductase SDR... 66 1e-09 UniRef50_A0R6X9 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte... 66 1e-09 UniRef50_Q0DM18 Cluster: Os03g0833100 protein; n=5; Oryza sativa... 66 1e-09 UniRef50_Q6IDG8 Cluster: RH36352p; n=2; Drosophila melanogaster|... 66 1e-09 UniRef50_A0DCG9 Cluster: Chromosome undetermined scaffold_45, wh... 66 1e-09 UniRef50_A2BJK2 Cluster: Short chain dehydrogenase; n=1; Hyperth... 66 1e-09 UniRef50_P37079 Cluster: Sorbitol-6-phosphate 2-dehydrogenase; n... 66 1e-09 UniRef50_UPI000050F7E5 Cluster: COG1028: Dehydrogenases with dif... 65 1e-09 UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 65 1e-09 UniRef50_Q6MBQ9 Cluster: Putative uncharacterized protein; n=1; ... 65 1e-09 UniRef50_Q8GR61 Cluster: Xylitol dehydrogenase; n=2; Gluconobact... 65 1e-09 UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2; Corynebac... 65 1e-09 UniRef50_Q1YS63 Cluster: Putative dehydrogenase; n=1; gamma prot... 65 1e-09 UniRef50_Q1AYC7 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09 UniRef50_Q0S7P7 Cluster: Short chain dehydrogenase; n=7; Bacteri... 65 1e-09 UniRef50_Q0B254 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09 UniRef50_A7U537 Cluster: Short-chain dehydrogenase/reductase; n=... 65 1e-09 UniRef50_A6CW76 Cluster: Putative short chain dehydrogenase; n=1... 65 1e-09 UniRef50_A4CPX8 Cluster: Short chain dehydrogenase; n=2; Bacteri... 65 1e-09 UniRef50_A2U5Y6 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09 UniRef50_A1ULZ8 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09 UniRef50_Q75DB1 Cluster: ABR248Wp; n=4; Eremothecium gossypii|Re... 65 1e-09 UniRef50_Q6CFW0 Cluster: Yarrowia lipolytica chromosome B of str... 65 1e-09 UniRef50_Q8TTL5 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 65 1e-09 UniRef50_Q8TMH3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 65 1e-09 UniRef50_UPI00004996DD Cluster: 3-oxoacyl-(acyl-carrier protein)... 65 2e-09 UniRef50_Q8YVT0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 65 2e-09 UniRef50_Q8DIS9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 65 2e-09 UniRef50_Q7ULD3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 65 2e-09 UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09 UniRef50_Q39N51 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09 UniRef50_Q2GA84 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09 UniRef50_Q2IVE1 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09 UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified Gamma... 65 2e-09 UniRef50_Q12B22 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09 UniRef50_Q0VQZ0 Cluster: Oxidoreductase; n=4; Gammaproteobacteri... 65 2e-09 UniRef50_Q0SJT0 Cluster: Short chain dehydrogenase; n=13; Actino... 65 2e-09 UniRef50_Q029B5 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09 UniRef50_A7IJL6 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09 UniRef50_A7DJ01 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09 UniRef50_A5MZ18 Cluster: FabG2; n=2; Clostridia|Rep: FabG2 - Clo... 65 2e-09 UniRef50_A3JK09 Cluster: Oxidoreductase; n=1; Marinobacter sp. E... 65 2e-09 UniRef50_A6XGT9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 65 2e-09 UniRef50_Q9N5G3 Cluster: Dehydrogenases, short chain protein 14;... 65 2e-09 UniRef50_Q4WR19 Cluster: Short chain dehydrogenase, putative; n=... 65 2e-09 UniRef50_Q2UTV6 Cluster: Dehydrogenases with different specifici... 65 2e-09 UniRef50_A5DPQ3 Cluster: Putative uncharacterized protein; n=2; ... 65 2e-09 UniRef50_A3H6D0 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09 UniRef50_Q9RKB7 Cluster: Probable 3-oxoacyl-[acyl carrier protei... 64 2e-09 UniRef50_Q97NV2 Cluster: Oxidoreductase, short chain dehydrogena... 64 2e-09 UniRef50_Q8EDE2 Cluster: Oxidoreductase, short chain dehydrogena... 64 2e-09 UniRef50_Q7MAW1 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 64 2e-09 UniRef50_Q2KXQ0 Cluster: Probable short chain dehydrogenase/redu... 64 2e-09 UniRef50_Q7P5A9 Cluster: Ketoacyl reductase hetN; n=3; Fusobacte... 64 2e-09 UniRef50_Q2IVN1 Cluster: Short-chain dehydrogenase/reductase; n=... 64 2e-09 UniRef50_Q1ILJ4 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09 UniRef50_Q11G59 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09 UniRef50_A5TX02 Cluster: Short-chain alcohol dehydrogenase; n=3;... 64 2e-09 UniRef50_A4WBV4 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09 UniRef50_A4ET39 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 64 2e-09 UniRef50_A3SL40 Cluster: Putative uncharacterized protein; n=1; ... 64 2e-09 UniRef50_A0YDM1 Cluster: Putative 3-ketoacyl-CoA reductase; n=3;... 64 2e-09 UniRef50_A0XX22 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 64 2e-09 UniRef50_A0QGC5 Cluster: Sorbitol utilization protein SOU1; n=3;... 64 2e-09 UniRef50_A0GDT9 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09 UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methano... 64 2e-09 UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09 UniRef50_Q9AK65 Cluster: Putative glucose 1-dehydrogenase; n=2; ... 64 3e-09 UniRef50_Q3WFP9 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09 UniRef50_Q2BDF6 Cluster: Putative uncharacterized protein; n=1; ... 64 3e-09 UniRef50_Q1NK00 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09 UniRef50_Q13I70 Cluster: Putative short-chain dehydrogenase/redu... 64 3e-09 UniRef50_Q11BT3 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09 UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09 UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09 UniRef50_A6ELE5 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09 UniRef50_A5P5M1 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09 UniRef50_A4XEP3 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09 UniRef50_A4BWQ4 Cluster: Putative short chain dehydrogenase; n=1... 64 3e-09 UniRef50_A3IBN0 Cluster: Predicted short chain dehydrogenase; n=... 64 3e-09 >UniRef50_Q1G151 Cluster: Putative alcohol dehydrogenase; n=1; Bombyx mori|Rep: Putative alcohol dehydrogenase - Bombyx mori (Silk moth) Length = 274 Score = 175 bits (425), Expect = 1e-42 Identities = 85/199 (42%), Positives = 126/199 (63%), Gaps = 1/199 (0%) Frame = +3 Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKFYRS 203 DKV +TG A G+G +V+ LL E +H+A LD+A+ G +L+ +L K+G + KF + Sbjct: 14 DKVFLVTGGAAGVGAGLVKALLFENARHVAFLDVADREGAALEAQLIIKFGALRVKFIKC 73 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 383 DV DE V+ + +D VIN+AA+++ + + I++N T + STLKA++I Sbjct: 74 DVGDERQLASAYKQVLDKYKRLDGVINSAAVLSVDDNSFNRMIDINFTGTVNSTLKALDI 133 Query: 384 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 563 MG GG GG ++N+SS+ AL + +P+Y ATK+AVLQFS +G E F++T VRVL+V Sbjct: 134 MGADKGGSGGVIVNISSLLALNLTSHLPVYAATKAAVLQFSIRMGTQEQFTRTKVRVLSV 193 Query: 564 CFGATDTALLTDEKLGTFD 620 C G TDTA+L L FD Sbjct: 194 CLGPTDTAILYKNNLTKFD 212 >UniRef50_Q6RUR3 Cluster: Putative alcohol dehydrogenase; n=2; Neoptera|Rep: Putative alcohol dehydrogenase - Gryllotalpa orientalis (Oriental mole cricket) Length = 266 Score = 157 bits (381), Expect = 2e-37 Identities = 85/216 (39%), Positives = 124/216 (57%), Gaps = 4/216 (1%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 200 K K +TG ATGIG + V+ LL GV+ +A+ D+ E G + +LN ++G K F + Sbjct: 4 KGKYALVTGGATGIGLAYVKELLRHGVQAVAVADLDERKGDNSVKQLNDEFGAGKAIFIK 63 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 380 DVT+++ G+D+VINNA +++DS ++ I +NVTA+ T A + Sbjct: 64 CDVTNKDDLEATFRKAAATFKGLDIVINNAGILDDSR--WETEIAINVTAVARGTWLAFD 121 Query: 381 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560 +MGK+ GG+GG V+N++S+ L P+Y ATK AV+ S G P HF +TGVRVLT Sbjct: 122 LMGKNKGGRGGVVVNIASILGLQAMAGCPVYVATKHAVVGLSRSFGMPYHFDRTGVRVLT 181 Query: 561 VCFGATDTALLTDEKLGTFDKYLESSC---LDQLKK 659 +C G TDT L+++ F L C LD L K Sbjct: 182 MCPGVTDTPLISEAHHRQFTDDLGKECGRELDALPK 217 >UniRef50_Q6NYE8 Cluster: Zgc:56585 protein; n=5; Clupeocephala|Rep: Zgc:56585 protein - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 270 Score = 153 bits (372), Expect = 3e-36 Identities = 81/208 (38%), Positives = 126/208 (60%), Gaps = 5/208 (2%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 200 KDKV +TGAA G+G S V IL+ G K +A++D+ + G+ L+ LN +YG N+ +FY Sbjct: 4 KDKVAVVTGAAQGLGRSFVEILMKNGSK-VALIDVNKSLGEELKTNLNKEYGPNRAEFYT 62 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 380 +DV+ EE F G+L +V++ G ID++ NNA ++N+ ++K I +N+ ++ T A+E Sbjct: 63 ADVSSEEDFKGVLKKIVEQFGQIDIMCNNAGIINEKH--WEKTIAINLGGVVRGTYLALE 120 Query: 381 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560 M K +GG GG ++NV+S+A L V PIY ATK V+ FS + S GVR+ Sbjct: 121 YMKKENGGSGGVIVNVASMAGLGPLPVAPIYTATKHGVVGFSRAMAVVSKLSNYGVRINV 180 Query: 561 VCFGATDTALL----TDEKLGTFDKYLE 632 +C T+LL ++E G+F + E Sbjct: 181 LCPWFVKTSLLSLLNSEEHTGSFSQMKE 208 >UniRef50_UPI0000DB7440 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase; n=1; Apis mellifera|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase - Apis mellifera Length = 266 Score = 149 bits (360), Expect = 8e-35 Identities = 75/182 (41%), Positives = 117/182 (64%), Gaps = 1/182 (0%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 200 KDK V ITG A+G+G ++ R LL G IA++D AEE+GK LN ++G N+T FY Sbjct: 4 KDKRVIITGVASGLGLTISRELLRNGASIIAMID-AEESGKETVDILNKEFGRNRTIFYH 62 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 380 ++ + F V+ GG+++++NNA + N++ + K I+VNVT++I +TL I+ Sbjct: 63 CNIANNSEFDDTFKKAVKALGGLEILVNNADVTNETD--FMKTIDVNVTSVIRATLLGIQ 120 Query: 381 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560 M K GGKGG ++N+SS+A L + +P+Y ATK AV+ FS +P H+ +TGV++L Sbjct: 121 QMQKDLGGKGGAIVNISSLAGLYAAPQLPVYSATKHAVVSFSRSFAQPYHYKRTGVKILV 180 Query: 561 VC 566 +C Sbjct: 181 MC 182 >UniRef50_UPI00015B5316 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 329 Score = 142 bits (343), Expect = 9e-33 Identities = 69/195 (35%), Positives = 115/195 (58%), Gaps = 1/195 (0%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 200 KDK + GA G+G + + LL GV + ++D+ E G++ LN ++G N+ F + Sbjct: 71 KDKKAMVIGACDGLGMAFSKELLRNGVARVLMIDMNETLGRAQADRLNEEFGRNRATFTK 130 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 380 DVT F V G +D+++NNAA++ D + ++ I+ NVTA+ +++ ++ Sbjct: 131 CDVTKGSEFDACFKDAVNTLGALDIIVNNAAMI-DEVNFHR-TIDTNVTAVFRASMMGVQ 188 Query: 381 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560 MGK +GGKGG ++NV+SV L +PIY AT AV+ FS +P H+ +TGVR++ Sbjct: 189 QMGKDTGGKGGVIVNVASVLGLEACPQLPIYSATNHAVIAFSRSFSQPYHYQRTGVRLMV 248 Query: 561 VCFGATDTALLTDEK 605 +C G T++ +L + K Sbjct: 249 LCPGLTESPMLENLK 263 >UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 261 Score = 142 bits (343), Expect = 9e-33 Identities = 70/191 (36%), Positives = 118/191 (61%), Gaps = 1/191 (0%) Frame = +3 Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206 +KV ITG A GIG ++V+ LL+ G+K +A+ D+ K + ++L KYGN+ + Y D Sbjct: 5 NKVAIITGGAGGIGAAIVKRLLEHGIKLVALFDLDNSNTKKIFMDLQKKYGNRVELYPCD 64 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK-AIEVNVTALITSTLKAIEI 383 VT++ F + V++ ID+++NNA + +D I+ + I++N A++ +L IE Sbjct: 65 VTNKAQFEENFDKVLKTHKTIDILLNNAGIGSD---IHTELMIDLNYKAVVLGSLLFIER 121 Query: 384 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 563 +GKH GGKGG ++N +S+ L +P+Y +TK AV+ F+ C+ + TGVRV+ + Sbjct: 122 LGKHKGGKGGIIVNTASILGLRNFDCLPVYCSTKHAVVSFTRCL--DVQYDTTGVRVVAI 179 Query: 564 CFGATDTALLT 596 C G T+T L++ Sbjct: 180 CPGVTETPLVS 190 >UniRef50_UPI00015B4C63 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 271 Score = 139 bits (337), Expect = 5e-32 Identities = 72/202 (35%), Positives = 118/202 (58%), Gaps = 8/202 (3%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKF 194 E +KV+ ITG G+G + LL+ G K +A+ D+ E G+S +L+ ++G + F Sbjct: 2 EISNKVIIITGGVGGMGFETAKALLNHGAKFVALFDLTETDGQSAIEKLDKEFGKGRAGF 61 Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALI------ 356 Y D+ + F N ++++ G IDV+INNA + N+ ++ + VNV + I Sbjct: 62 YPGDIVIDSEFEDNFNRIIKDHGSIDVLINNAGIANEQN--IERLVNVNVVSSIDKNILR 119 Query: 357 -TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533 + L A+ MGKH GGKGG ++NV+++ L ++P Y ATK A++ F+ C+ E+F Sbjct: 120 ASQILLALNHMGKHKGGKGGAIVNVNAILGLIDCPILPFYSATKHAIIGFTRCM--KENF 177 Query: 534 SKTGVRVLTVCFGATDTALLTD 599 + TGVRV++VC G T T L+ + Sbjct: 178 ATTGVRVMSVCPGVTKTNLIKE 199 >UniRef50_UPI0000513348 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase; n=2; Apis mellifera|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase - Apis mellifera Length = 263 Score = 139 bits (336), Expect = 6e-32 Identities = 73/205 (35%), Positives = 118/205 (57%), Gaps = 1/205 (0%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-K 185 M+ K+K ITG G+G + LL+ G K +A+LD++ G+ L ++G K Sbjct: 1 MTDNIKNKTALITGGTVGLGLIYAKRLLENGAKCVALLDLSSSPGQQTVNNLEKEFGKGK 60 Query: 186 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 365 FY DV++ F + VV + G+D+VINNA + ND +++ + +NV +I + Sbjct: 61 AIFYACDVSNINEFEAVFKKVVNDLNGLDIVINNAGIYNDKK--WEQTMCINVGGVIQGS 118 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 L A + M K GGKGGT++N++S+ AL + P+Y A+K VL FS + R +++ TG Sbjct: 119 LLAFDHMSKLKGGKGGTIVNIASIVALDIIYSNPVYCASKHFVLAFSRSLAR--YYNNTG 176 Query: 546 VRVLTVCFGATDTALLTDEKLGTFD 620 +R+L +C G T T+LL + +FD Sbjct: 177 IRILIMCPGVTTTSLLENPLSKSFD 201 >UniRef50_UPI00015B573D Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 279 Score = 136 bits (330), Expect = 3e-31 Identities = 73/204 (35%), Positives = 118/204 (57%), Gaps = 1/204 (0%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 200 KDKV+ +TG A GIG V L++G +++AILDI E +L ++G ++ Y Sbjct: 11 KDKVIIVTGGANGIGLECVLEFLEKGARYVAILDITPE--NFTADKLQEEFGTHRVDLYH 68 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 380 D+ +EE F V+++ +D++IN+A + N++ + ++VNV I L AIE Sbjct: 69 CDIANEEEFRSNFKKVIEKHNYVDILINDAGVANENDTA--RLLDVNVKGTILGNLMAIE 126 Query: 381 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560 MGKH GG+GG V+NV+SV L HV+P+Y A+K A++ F+ + + + GV+++ Sbjct: 127 HMGKHKGGRGGVVVNVASVIGLLNCHVLPVYSASKHAIVSFTRSM--KSNCDRLGVKIIA 184 Query: 561 VCFGATDTALLTDEKLGTFDKYLE 632 VC G T T L + + T YL+ Sbjct: 185 VCPGHTRTKLNFELAVETSVNYLD 208 >UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=3; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 273 Score = 132 bits (318), Expect = 1e-29 Identities = 67/192 (34%), Positives = 117/192 (60%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197 E KDKVV ITG +GIG S+ + +L G K++A+ ++ E + + EL+ +Y ++ FY Sbjct: 19 EVKDKVVVITGGTSGIGLSIAKHMLKNGAKYVALFELDHENSRIVFDELHKQYHDRIGFY 78 Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 377 DVT + + V++ ID++INNA + +D+ + ++++N+ AL+ ++ K I Sbjct: 79 PCDVTKTDLIYNNFDKVMESHKTIDILINNAGIADDNKP--ELSVDINLKALVVASYKFI 136 Query: 378 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557 +GKH GGKGG ++N++S+A + S +P+Y ATK V+ F+ + + TGVRVL Sbjct: 137 ARIGKHKGGKGGVIVNIASIAGIV-SGFLPVYCATKHGVVGFTRTL--QMSYGLTGVRVL 193 Query: 558 TVCFGATDTALL 593 +C T+T ++ Sbjct: 194 AICPSFTNTPIV 205 >UniRef50_UPI00015B42E2 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 266 Score = 131 bits (317), Expect = 1e-29 Identities = 71/193 (36%), Positives = 113/193 (58%), Gaps = 3/193 (1%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQV--ELNSKYG-NKTKF 194 KDKV +TG GIG + V+ LL G K++AI D+ ++ ++ ++G +K F Sbjct: 4 KDKVAIVTGGTGGIGFATVQALLRHGAKYVAIFDLDSMHTRAASCIHKVEEEFGKDKADF 63 Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 374 Y DVT + F + +V Q +D+++N A++ ++ + I++N+TA++T TL Sbjct: 64 YTCDVTIQSEFAARYDEIVGMQRTVDILVNYASIASEPRAHHM--IDINLTAVVTCTLIG 121 Query: 375 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554 I+ MG+H G+GG ++NV SV LT S PIY ATK V F+ + +H+ GVRV Sbjct: 122 IDRMGRHHNGRGGAIVNVCSVFGLTTSPAFPIYTATKYGVYGFTKSL--KDHYEHLGVRV 179 Query: 555 LTVCFGATDTALL 593 + VC G T+T+LL Sbjct: 180 MAVCPGLTETSLL 192 >UniRef50_UPI000051334A Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1) isoform 1; n=1; Apis mellifera|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1) isoform 1 - Apis mellifera Length = 264 Score = 128 bits (309), Expect = 1e-28 Identities = 62/188 (32%), Positives = 111/188 (59%), Gaps = 1/188 (0%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 206 K+ +TG A GIG R LL G K +A+LD+++ G+S +LN+++G ++ F D Sbjct: 6 KIAIVTGGANGIGFCTARKLLRNGAKAVALLDLSDSGGESAAADLNNEFGKDRAIFIACD 65 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 386 V+ E F V+ +++++N A +M+D+ ++ +++N ++ T+ + M Sbjct: 66 VSKNEQFQESFKKVIDTYETLNILVNIAGIMDDAD--WEIMVDINYKGIVYGTILGLHTM 123 Query: 387 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 566 GK+ GG GG ++N+SSVA L + PIY T+ A++ F+ + ++ KTG+R+LT+C Sbjct: 124 GKYKGGNGGIIVNMSSVAGLEGIPIAPIYGGTQYAIVGFTQSL--KHYYEKTGIRMLTIC 181 Query: 567 FGATDTAL 590 G T TA+ Sbjct: 182 PGLTTTAM 189 >UniRef50_UPI00015B5A58 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 263 Score = 127 bits (306), Expect = 3e-28 Identities = 70/193 (36%), Positives = 115/193 (59%), Gaps = 3/193 (1%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKS-LQVE-LNSKYGN-KTKF 194 K+KV+ ITG G+ + ++LL ++IA+ D E+ + LQ++ ++G + F Sbjct: 4 KNKVIIITGGLGGLATATTQVLLKHEPRYIALFDTEEKNSYAELQLKKFEQEFGEGRVGF 63 Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 374 Y SDV ++ F + V++ +D++IN A ++ D+ + I+VN L+ TL A Sbjct: 64 YASDVRNQHQFEEKYDQVLKSHKSVDILINLAGILCDADT--ELTIDVNFKGLVFCTLTA 121 Query: 375 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554 I+ MG H GG+GGT+INVSS+ L P+Y ATK AV+ F+N + H++KTGVR Sbjct: 122 IDKMGIHRGGRGGTIINVSSIVGLMFHEDFPVYVATKHAVVAFTNSL--KSHYAKTGVRA 179 Query: 555 LTVCFGATDTALL 593 +T+C G T T+++ Sbjct: 180 MTMCPGLTSTSMI 192 >UniRef50_UPI0000D57364 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1); n=1; Tribolium castaneum|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1) - Tribolium castaneum Length = 312 Score = 126 bits (304), Expect = 5e-28 Identities = 66/188 (35%), Positives = 107/188 (56%), Gaps = 1/188 (0%) Frame = +3 Query: 33 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 209 V ITG A GIG ++ R+ L G+ +A+ D ++E G+ +L ++G NK F+ D+ Sbjct: 54 VAIITGGAEGIGLAIARVFLKCGISGLAVADCSKEKGEESIKQLACEFGENKVLFFDGDM 113 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 389 + + F + + +++V+NNA +MND ++ + N++ I TL ++ M Sbjct: 114 SQSKAFDRVFKETLNHFENVNIVVNNAGVMNDVN--WECQVNTNLSGTIIGTLLGMQYMS 171 Query: 390 KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCF 569 K S G+GGT+INV+S+ L S PI+ T+ ++ FS IG HF +TGVRV +C Sbjct: 172 KTSLGQGGTIINVASIMGLIPSSGYPIHTLTQFGIVGFSRAIGNLNHFDRTGVRVTALCP 231 Query: 570 GATDTALL 593 G T+T LL Sbjct: 232 GLTNTKLL 239 >UniRef50_UPI00015B5FC8 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 267 Score = 125 bits (302), Expect = 9e-28 Identities = 77/219 (35%), Positives = 126/219 (57%), Gaps = 6/219 (2%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE---EAGKSLQVELNSKYGNKT 188 E K+KV +TG GIG V+ L+ ++ +AI+D+ + EA + +LN ++G + Sbjct: 2 EIKNKVAIVTGGIGGIGLVTVQHLIRSKIQFVAIIDLPKSDSEAAVANLSKLNKEFGKGS 61 Query: 189 -KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 365 ++Y D+T+ + F I V+ + +D++IN A ++ND+ I VN TA++ S+ Sbjct: 62 YQYYSCDLTNIQEFRAIYEKVIALKKYVDILINAAGILNDNA--MNLCINVNFTAVVNSS 119 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 + AIE M K GGKGG V+NV+S+A + PIY ATK AV+ F+ + +P H G Sbjct: 120 MIAIEHMRKDKGGKGGVVVNVASIAGIVDFPYNPIYNATKHAVVAFARSL-KP-HNKIIG 177 Query: 546 VRVLTVCFGATDTALLTDEKL--GTFDKYLESSCLDQLK 656 VRV+ +C G TDT L+ + L FD +++ +D + Sbjct: 178 VRVVCICPGVTDTGLVAFDHLYKSLFD-FIDPKIVDDFR 215 >UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|Rep: CG4899-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 278 Score = 125 bits (301), Expect = 1e-27 Identities = 68/199 (34%), Positives = 116/199 (58%), Gaps = 1/199 (0%) Frame = +3 Query: 6 KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNK 185 KMS K+ VV TG A GIG V + LL G +AI+D+ + + V+L + + + Sbjct: 17 KMSFRGKNAVV--TGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEF--VKLRAAHPTQ 72 Query: 186 T-KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITS 362 + + DV +++ + + G ID+V+N A + ND ++ + VN+ +I S Sbjct: 73 SVMIIKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKD--VQRTLLVNLGGIINS 130 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 TL A+ MGK +GGKGG V+N+SSV L ++P+Y ATK+ ++ F+ C+ +++ ++ Sbjct: 131 TLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRS 190 Query: 543 GVRVLTVCFGATDTALLTD 599 G++ +TVC GAT T + T+ Sbjct: 191 GIKFVTVCPGATMTDMFTN 209 >UniRef50_Q1HPX6 Cluster: Alcohol dehydrogenase; n=1; Bombyx mori|Rep: Alcohol dehydrogenase - Bombyx mori (Silk moth) Length = 289 Score = 124 bits (299), Expect = 2e-27 Identities = 80/209 (38%), Positives = 112/209 (53%), Gaps = 3/209 (1%) Frame = +3 Query: 3 LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG- 179 LK +E + KVV ITGAA GIG ++ L G K I ILDI G ELN KYG Sbjct: 25 LKKENEIEGKVVVITGAAQGIGYAIADNFLKNGAKVIIILDINVPKGIQAAKELNCKYGK 84 Query: 180 NKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALIT 359 NK +F D+T + I + ++ +DV++NNA + + +K + N A I Sbjct: 85 NKAEFIECDITKDLE--RISKIIYKKYKYVDVLVNNAGIFKEIKP--RKLLLTNAVATIE 140 Query: 360 STLKAIEIMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536 +LK +E M K GKGGT+IN++S P Y TK A++ FS +G ++ Sbjct: 141 FSLKFMENMRKDKLSGKGGTIINIASTVVHYIDPFFPTYRGTKFAIMGFSRSLGHEYNYK 200 Query: 537 KTGVRVLTVCFGATDTAL-LTDEKLGTFD 620 K GVRVLT+C G T+T L L + K+ + D Sbjct: 201 KNGVRVLTICPGETNTTLGLDNTKVNSED 229 >UniRef50_P15428 Cluster: 15-hydroxyprostaglandin dehydrogenase [NAD+]; n=29; Euteleostomi|Rep: 15-hydroxyprostaglandin dehydrogenase [NAD+] - Homo sapiens (Human) Length = 266 Score = 122 bits (293), Expect = 1e-26 Identities = 66/203 (32%), Positives = 114/203 (56%), Gaps = 2/203 (0%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 206 KV +TGAA GIG + LL +G K +A++D EAG + L+ ++ KT F + D Sbjct: 6 KVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 386 V D++ VV G +D+++NNA + N+ ++K +++N+ ++I+ T ++ M Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN--WEKTLQINLVSVISGTYLGLDYM 122 Query: 387 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 566 K +GG+GG +IN+SS+A L P+Y A+K ++ F+ + +GVR+ +C Sbjct: 123 SKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAIC 182 Query: 567 FGATDTALLTD-EKLGTFDKYLE 632 G +TA+L EK +Y+E Sbjct: 183 PGFVNTAILESIEKEENMGQYIE 205 >UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 337 Score = 121 bits (292), Expect = 1e-26 Identities = 65/220 (29%), Positives = 118/220 (53%), Gaps = 1/220 (0%) Frame = +3 Query: 3 LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG- 179 L++S K V ITG A G+G + L G I I+DI + AGK + + +G Sbjct: 37 LEISGVVSGKNVLITGGAAGLGHAFFNHFLQFGANKICIIDIDDVAGKKIVASTDKSHGV 96 Query: 180 NKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALIT 359 K F +DV+ + V+ +D+V+NNA ++++ +++ I VN+ +I+ Sbjct: 97 GKVIFIHADVSRHSEIVAGFQKAVKLMDAVDIVVNNAGILDERR--WEREIAVNLNGMIS 154 Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539 L +++ MG+ GG+GG ++NV+ + + +P+Y ATK A++ S + P + + Sbjct: 155 VALLSMQYMGRDMGGRGGILVNVAEHMDVHCTAQLPVYTATKQAIIGLSQSLAAPCNTER 214 Query: 540 TGVRVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKK 659 TGVRV+T+C G T+TAL D + +++ + L++ Sbjct: 215 TGVRVITLCPGLTETALTIDSPNKLLSRVMKADFVKNLEQ 254 >UniRef50_UPI0000E47587 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase (NAD+), partial; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase (NAD+), partial - Strongylocentrotus purpuratus Length = 298 Score = 121 bits (292), Expect = 1e-26 Identities = 68/202 (33%), Positives = 113/202 (55%), Gaps = 2/202 (0%) Frame = +3 Query: 6 KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-N 182 K+ + + V ITGAA G G++ LL V+ I I+D GK+ + ELN KYG + Sbjct: 37 KIKMKIQGAVALITGAAEGFGKAFTEELLKRSVRGIGIVDFNAAKGKATETELNKKYGED 96 Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITS 362 K +F++ DV+ ++ + ++ GID+V NNA + D + ++K ++V++ A++ Sbjct: 97 KVRFFQCDVSSKDQLEDAFSKTLEHYKGIDIVCNNAGI-GDELN-WEKTVDVDLVAVMRG 154 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH-FSK 539 T A + M K+ GG+GG VIN++S+A L + P Y A K VL FS + + F+ Sbjct: 155 TFLAKQYMDKNKGGRGGIVINIASMAGLYPMPLAPAYSAAKHGVLGFSRALAIADKVFNP 214 Query: 540 TGVRVLTVCFGATDTALLTDEK 605 VR+ +C ++TA+L K Sbjct: 215 ENVRLNCLCPSFSETAILQQMK 236 >UniRef50_Q7PY55 Cluster: ENSANGP00000013280; n=4; Endopterygota|Rep: ENSANGP00000013280 - Anopheles gambiae str. PEST Length = 183 Score = 119 bits (287), Expect = 6e-26 Identities = 67/183 (36%), Positives = 96/183 (52%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 K+KV +TGAATG+G + LL G K + I D+ +AG+ EL +YG + F Sbjct: 4 KNKVALVTGAATGLGRAFSEELLKHGAK-VVICDLDSDAGELTVEELEKQYGARVLFCHC 62 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 383 DVTD F V +++VINNA +MND+ ++ ++VN+ I TL A + Sbjct: 63 DVTDYIQFEEAFEYTVNMFKEVNIVINNAEIMNDNF--WELEVDVNLNGAIRGTLLAQKF 120 Query: 384 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 563 M K G GG ++N+ S ++T PIY ATK A+L + G P H + T VR Sbjct: 121 MDKSKGKGGGVLVNIGSGVSVTPQLSTPIYTATKHAILGLTKACGDPFHHANTNVRAFAY 180 Query: 564 CFG 572 C G Sbjct: 181 CPG 183 >UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to hydroxyprostaglandin dehydrogenase 15 (NAD); n=2; Tribolium castaneum|Rep: PREDICTED: similar to hydroxyprostaglandin dehydrogenase 15 (NAD) - Tribolium castaneum Length = 479 Score = 119 bits (286), Expect = 7e-26 Identities = 62/199 (31%), Positives = 109/199 (54%), Gaps = 2/199 (1%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-K 185 M + +KV I+GAA+GIG ++ + LL G++ + I D+ +E G+ E+ +++G+ + Sbjct: 1 MPFDINNKVALISGAASGIGLTIAKELLRNGLRGVTIADVNKELGEKALQEIENEFGSGR 60 Query: 186 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 365 F +DV+ + F + ID+++N A ++NDSI +++ I +NV + Sbjct: 61 AIFVLTDVSSMKSFEDAFQKTINTFKNIDILVNGAGVLNDSI--WQQEIAINVNGTVHGI 118 Query: 366 LKAIE-IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 L A+E + K+ G ++N SS+A + PIY TK A+ + G H+ +T Sbjct: 119 LLALENYIPKYKTDSEGVIVNFSSIAGVAAFPAFPIYTGTKFAIFGMTKAFGDEAHYERT 178 Query: 543 GVRVLTVCFGATDTALLTD 599 VR++ +C G TDT LL D Sbjct: 179 KVRIMAICPGPTDTPLLRD 197 Score = 93.5 bits (222), Expect = 4e-18 Identities = 52/172 (30%), Positives = 91/172 (52%), Gaps = 2/172 (1%) Frame = +3 Query: 75 VVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDVTDEEHFLGILNAVV 251 +VR G + I DI E G+ + E+ +++G NK + +DVT + + + Sbjct: 233 IVRNAPSGGAWGVTIADINTELGEKVLQEIINEFGKNKAIYILTDVTCKNSYEAAFKKTI 292 Query: 252 QEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE-IMGKHSGGKGGTVINV 428 + +D+V+N A ++N+ +++ +++N+ + T+ A+E + K+ G G ++N+ Sbjct: 293 ETFQNLDIVVNGAGIVNELD--WQQEVDINLNGTLHGTILALENYIPKYKSGSEGVIVNI 350 Query: 429 SSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCFGATDT 584 SS A L PIY TK AV+ S G H+ +T VRVLT C G T+T Sbjct: 351 SSAAILDCFPPYPIYTGTKFAVMGISKSFGAEVHYKRTKVRVLTACPGVTET 402 >UniRef50_UPI0000D57365 Cluster: PREDICTED: similar to CG4899-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG4899-PA, isoform A - Tribolium castaneum Length = 295 Score = 114 bits (274), Expect = 2e-24 Identities = 64/191 (33%), Positives = 97/191 (50%), Gaps = 1/191 (0%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 206 KV ITG + GIG +V +L E K++A++ + G+ LNS YG NK F+ D Sbjct: 52 KVALITGGSDGIGLAVAHEILSENSKNVALIGVDNTKGRESVHALNSTYGRNKAVFFNCD 111 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 386 V + N V++E G ID+VIN A + + ++K I N+ I TL+A +M Sbjct: 112 VESKVQVNDCFNKVIKEFGSIDIVINAAGVFDGRC--WEKEIMTNLVGTIHCTLEAYRVM 169 Query: 387 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 566 K G GG ++N S + + P A+ ++ S G +F TGVRV+T+C Sbjct: 170 SKDCSGSGGVILNFSGLHGVKPLFPAPTLSASFHGIIGLSRSFGHETNFKTTGVRVVTLC 229 Query: 567 FGATDTALLTD 599 G T+T + D Sbjct: 230 PGITNTNFIKD 240 >UniRef50_UPI00015B572C Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 268 Score = 108 bits (260), Expect = 1e-22 Identities = 70/219 (31%), Positives = 116/219 (52%), Gaps = 5/219 (2%) Frame = +3 Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIA----EEAGKSLQVELNSKYG-NKTK 191 +KV +TG GIG +V+ L G K +AI D+ EE +L+ +L ++ + Sbjct: 5 NKVGVVTGGLRGIGYVIVQHFLRRGAKFVAIFDLDVEEHEEVVNALK-QLEQEFAAQRFS 63 Query: 192 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 371 +Y DVT+ + F+ + V G +D+++NNA + + + VN T++I T+ Sbjct: 64 YYCCDVTNFKKFIACYDEVYTTNGAVDILVNNAGVFAEHD--QDLTVAVNFTSVIHCTMH 121 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 AIE MG + GGKGG ++ + S+ AL +P+Y ATK A+ F ++ +K GVR Sbjct: 122 AIERMGTNKGGKGGVIVTIGSICALISLSTIPVYSATKGALACFVR--STKDYNAKYGVR 179 Query: 552 VLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKKGFI 668 ++ +C G T T K+ K ++S CLD + + FI Sbjct: 180 IVCLCPGMTKT------KMTHAVKAIKSYCLDFVPQKFI 212 >UniRef50_Q9I7R3 Cluster: CG18814-PA; n=3; Sophophora|Rep: CG18814-PA - Drosophila melanogaster (Fruit fly) Length = 285 Score = 103 bits (248), Expect = 3e-21 Identities = 69/217 (31%), Positives = 113/217 (52%), Gaps = 18/217 (8%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS-D 206 K V G GIG+ V+ LL + +K +AI D+ + L E ++ + FY+ D Sbjct: 6 KNVVYLGGFGGIGKKCVQELLKKQIKGLAIFDLIVD--DDLLAEWKKQHPDTEIFYQKMD 63 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMND-----SIGIYKKAIEVNVT-------- 347 +T + A ++ G DVV+N + L++D +I I +E+ ++ Sbjct: 64 ITQKSDIDAAYKATAEKLGHFDVVVNGSGLLDDRRIELTIQINLVILEIVLSKGFIYQYF 123 Query: 348 ---ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 518 +I STL A+E M K GG+GG ++N+SSVA L + +M IY +K+ V F+ + Sbjct: 124 LKVGVINSTLTALEYMDKSKGGRGGLIVNISSVAGLQPTPLMAIYSTSKTGVTTFTRAMA 183 Query: 519 RPEHFSKTGVRVLTVCFGATDTALLTD-EKLGTFDKY 626 P H++ +GV +T+C G T+T +L D +K TF Y Sbjct: 184 SPIHYAHSGVGFITICPGYTNTGILKDIDKKTTFPFY 220 >UniRef50_UPI0000D5767E Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase; n=2; Tribolium castaneum|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase - Tribolium castaneum Length = 255 Score = 102 bits (245), Expect = 7e-21 Identities = 60/192 (31%), Positives = 103/192 (53%), Gaps = 1/192 (0%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197 E K KV +TG A+GIG ++VR LL G+K ++++DI+E EL ++ F Sbjct: 3 ELKGKVALVTGGASGIGLAMVRELLKNGIKAVSVVDISENT------ELQD---SRVTFI 53 Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 377 ++DVT ++ + V +D+V+NNA ++ D I +K+ I++N+ A+I T A+ Sbjct: 54 KTDVTCKKQLQAAFDKTVATYNQLDIVVNNAGVI-DEID-WKRTIDINLVAVIEGTYLAL 111 Query: 378 EI-MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554 + K+ G ++N +SV L PIY +K V+ +G P + + VR+ Sbjct: 112 RTYLPKYKSEAEGVIVNTASVLGLCPLQSAPIYCTSKHGVVGLGRSLGGPHIYDEYKVRI 171 Query: 555 LTVCFGATDTAL 590 +T+C G DT + Sbjct: 172 VTICPGLVDTPM 183 >UniRef50_Q5P8S6 Cluster: Putative dehydrogenase; n=4; Proteobacteria|Rep: Putative dehydrogenase - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 267 Score = 98.7 bits (235), Expect = 1e-19 Identities = 67/211 (31%), Positives = 106/211 (50%), Gaps = 10/211 (4%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 M KV +++GAA+GIG ++ R+ EG + + D+ E G+++ + + G + Sbjct: 1 MKQNLSGKVAYVSGAASGIGAAIARVFAAEGAS-VLLGDVQVERGETVAAHIREQ-GGRA 58 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTA 350 F DV+DE + L V+E GG+D+++NNA L + + K + VNV Sbjct: 59 LFIHHDVSDERQWESALACAVEEFGGMDLLVNNAGIEQTGLLADVELADINKLLAVNVAG 118 Query: 351 LITSTLKAIEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527 +I AI M S GKGG++IN+SSVA L + + +Y ATK AV S Sbjct: 119 VILGHKHAIRTMRPGGSAGKGGSIINLSSVAGLIGTPALGVYSATKGAVRLLSKAAAVEC 178 Query: 528 HFSKTGVRVLTVCFGATDTAL---LTDEKLG 611 G+RV ++ G DT + L D+ +G Sbjct: 179 GRLGYGIRVNSIHPGLVDTDMGVKLVDDFVG 209 >UniRef50_A6YPS8 Cluster: Oxidoreductase; n=1; Triatoma infestans|Rep: Oxidoreductase - Triatoma infestans (Assassin bug) Length = 252 Score = 95.9 bits (228), Expect = 8e-19 Identities = 66/196 (33%), Positives = 105/196 (53%), Gaps = 8/196 (4%) Frame = +3 Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200 WKD+V +TGA+ GIGE++ R L + G+K +A L + + LQ + N+ G+ K Y+ Sbjct: 4 WKDRVAVVTGASAGIGEAIARALAEHGMK-VAALARRLDRLQKLQDDCNNFIGS-IKPYK 61 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-----MND-SIGIYKKAIEVNVTALITS 362 DVT+E + ++V + G I V++NNA L M D S G ++ E NV L+T Sbjct: 62 CDVTNETEIATTIKSIVSDLGPISVLVNNAGLYENVPMTDTSQGSCRQTYETNVIGLVTF 121 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVA--ALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536 T +EIM KH+ G +IN++S+A + M Y A+K AV + + Sbjct: 122 TQHVVEIMKKHN-ITDGHIININSLAGHVIIPKPGMANYTASKHAVTVLTESLKNELAAM 180 Query: 537 KTGVRVLTVCFGATDT 584 K+ +RV ++ G +T Sbjct: 181 KSKIRVTSISPGLVNT 196 >UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR; n=10; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 282 Score = 95.5 bits (227), Expect = 1e-18 Identities = 60/213 (28%), Positives = 107/213 (50%), Gaps = 8/213 (3%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197 E + +V +TG A+GIG V + EG K + I D+ +E G++L + G F+ Sbjct: 8 ELQGRVAIVTGGASGIGRGVAERFVAEGAK-VVIADVQDELGEALAEQC----GPNALFH 62 Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA--------LMNDSIGIYKKAIEVNVTAL 353 +DV D+E +++ V+ G +DV++NNA L N+ + + + + VN+ ++ Sbjct: 63 HTDVGDQEQMRRLVDVAVERFGALDVMVNNAGISSPLRRGLFNEDLEEFDRVMRVNLLSV 122 Query: 354 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533 + T A M +H GG ++IN+SS+ + +P+Y A+K+A+L F+ C Sbjct: 123 MAGTRDAGRYMSEHGGG---SIINLSSIGGIQAGGGVPVYRASKAAILHFTKCAA--IEL 177 Query: 534 SKTGVRVLTVCFGATDTALLTDEKLGTFDKYLE 632 + +RV + G T +L G + LE Sbjct: 178 AHYDIRVNCIAPGNIPTPILQSSATGEDRERLE 210 >UniRef50_Q9NAR7 Cluster: Alcohol dehydrogenase; n=23; Schizophora|Rep: Alcohol dehydrogenase - Bactrocera oleae (Olive fruit fly) Length = 258 Score = 95.1 bits (226), Expect = 1e-18 Identities = 59/188 (31%), Positives = 100/188 (53%), Gaps = 2/188 (1%) Frame = +3 Query: 33 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--KSLQVELNSKYGNKTKFYRSD 206 VVF+ G IG + ++ + V + D+ E A K+LQ +N K K + + D Sbjct: 8 VVFVGGLGF-IGYEACKQIMTKNVASFFVFDVLENAENIKALQA-INPK--TKVYYTKFD 63 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 386 +T++ V+ + IDV++N A ++ D + + +N+ LI +TL+AI +M Sbjct: 64 ITNKASIKSAFADVIAKVQYIDVLVNGAGILTDPN--VELTMNINLIGLINTTLEAIPLM 121 Query: 387 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 566 K+ G+GG ++N++SV L + IY A+K V+ FS I P +++ TG+ V T C Sbjct: 122 DKNKKGRGGLIVNIASVLGLEPAPPAAIYCASKFGVMGFSRSISDPYYYNLTGIAVATFC 181 Query: 567 FGATDTAL 590 G T+T L Sbjct: 182 PGLTETPL 189 >UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1; Planctomyces maris DSM 8797|Rep: Probable putative oxidoreductase - Planctomyces maris DSM 8797 Length = 270 Score = 93.5 bits (222), Expect = 4e-18 Identities = 61/196 (31%), Positives = 96/196 (48%), Gaps = 3/196 (1%) Frame = +3 Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200 ++D+VV +TG + GIGE R+ EG H+AIL AG+ L ELN K F + Sbjct: 18 FQDRVVIVTGGSKGIGEGCSRVFCAEG-GHVAILARGLHAGQDLARELNETGPGKAMFVQ 76 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTAL---ITSTLK 371 DV + E ++ VV++ G +D +INNA + ++ + + +IE + ST Sbjct: 77 CDVGEHEQIRSAIDLVVEQFGRLDCIINNAGVHPPAMSLEETSIEEMEQLMRVNFLSTFA 136 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 + H GT+IN+SS+ A+ H Y +TK A + F+ + + GVR Sbjct: 137 GAKYALPHLRKTKGTIINMSSMTAVLGQHHSTAYCSTKGAQVSFTKSLA--IELGEAGVR 194 Query: 552 VLTVCFGATDTALLTD 599 V + DT L+ D Sbjct: 195 VNAILPSNIDTPLMRD 210 >UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 266 Score = 93.5 bits (222), Expect = 4e-18 Identities = 61/194 (31%), Positives = 99/194 (51%), Gaps = 7/194 (3%) Frame = +3 Query: 33 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 209 V +TG GIG ++ + LLD K + +LDI E+ G L+ Y ++ F + DV Sbjct: 7 VAIVTGGVQGIGLAISKALLDRDGK-VCMLDINEKTGNETLKLLSENYSKHRVLFIKCDV 65 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALM---NDSI--GIYKKAIEVNVTALITSTLKA 374 T + G +D++ NNA + ND + G +K I++NV +I TL Sbjct: 66 TSQPQMEAAFQRTKDVFGRLDILCNNAGIAVRENDLLRSGAWKTIIDINVKGVILGTLLG 125 Query: 375 IEIMGKHSG-GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 ++ MG G GGT++NV+S+A L + P+Y A+K AV+ + + ++ VR Sbjct: 126 LDHMGVSGAKGHGGTIVNVASLAGLVPAPASPVYTASKHAVVGLTRTL--TSLWATECVR 183 Query: 552 VLTVCFGATDTALL 593 V +C TDTA++ Sbjct: 184 VNCICPSFTDTAMV 197 >UniRef50_Q9ABI1 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=7; Alphaproteobacteria|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Caulobacter crescentus (Caulobacter vibrioides) Length = 261 Score = 92.7 bits (220), Expect = 7e-18 Identities = 57/169 (33%), Positives = 91/169 (53%), Gaps = 7/169 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-YRSD 206 K FITG A G+G + R+L EG K +A+ DI +++ E+N+ +G T F + D Sbjct: 11 KKAFITGGAQGLGAAAGRMLAKEGAK-VALADINLAGAQAVADEINAAHGAGTAFAFELD 69 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTL 368 VT E+ ++ +L GG+ V++NNA + D G++KK + VNV ++ Sbjct: 70 VTQEDQWIDVLEKATAAMGGLSVLVNNAGIGGDGPIESLDFGLWKKVMSVNVDSVFLGAK 129 Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 515 A+ M H + G++IN+SS+A L + P Y A+K+AV S I Sbjct: 130 HALTHMRAH---QPGSIINLSSIAGLIANGNSPAYNASKAAVWLLSKNI 175 >UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase family protein; n=4; cellular organisms|Rep: Short-chain dehydrogenase/reductase family protein - Gramella forsetii (strain KT0803) Length = 249 Score = 91.1 bits (216), Expect = 2e-17 Identities = 66/204 (32%), Positives = 104/204 (50%), Gaps = 9/204 (4%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 K K + ITGA++GIGE+ L EGV ++ + EE K L+ +++ + G K Sbjct: 4 KGKTIIITGASSGIGEATAMRLAKEGV-NVVLTARREEKLKELKSKIDKENGGKALVIPG 62 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITST 365 DVT +E F +++ +E G ID +INNA LM N + K ++VN+ ++ Sbjct: 63 DVTKKEDFKNLIDKTKKEFGSIDGLINNAGLMPLSYVKNLHTDEWDKMVDVNIKGVLNGV 122 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 + M + K G +IN+SS AA +Y ATKSAV FS + R E K Sbjct: 123 AAVLPTMMEQ---KSGNIINISSSAARKIYPGGAVYCATKSAVKMFSEGL-RQELAPKFN 178 Query: 546 VRVLTVCFGATDTAL---LTDEKL 608 + + ++ G DT L +TD+++ Sbjct: 179 INITSIEPGFVDTELTDTITDDEI 202 >UniRef50_Q6C6W8 Cluster: Similar to tr|Q9WYD3 Thermotoga maritima TM0297 Oxidoreductase; n=7; Ascomycota|Rep: Similar to tr|Q9WYD3 Thermotoga maritima TM0297 Oxidoreductase - Yarrowia lipolytica (Candida lipolytica) Length = 291 Score = 91.1 bits (216), Expect = 2e-17 Identities = 61/195 (31%), Positives = 102/195 (52%), Gaps = 8/195 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV +TG A G+G S+ L G+K IAILD+ ++ G +L+ YG + +FY++DV Sbjct: 46 KVAIVTGGARGLGFSMAEGLCSVGLKGIAILDVQQDLGLDAIEKLHKAYGVQAQFYKADV 105 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 371 DEE I++ VV + G +DVV+N+A + + +++ I++N+ T Sbjct: 106 RDEESVNEIIDRVVHDLGSVDVVVNSAGVADLVHAAEYPADKFRRVIDINLNGSFLVTQA 165 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMP--IYFATKSAVLQFSNCIGRPEHFSKTG 545 A M K G GGTV+ ++S++ + P Y A+K+AV S + ++ Sbjct: 166 AARHMIKQ--GTGGTVVFIASMSGSIVNWPQPQSAYNASKAAVKHLSKSLA--AEWAVHN 221 Query: 546 VRVLTVCFGATDTAL 590 +R ++ G DTAL Sbjct: 222 IRCNSISPGYMDTAL 236 >UniRef50_Q5TWK5 Cluster: ENSANGP00000025423; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000025423 - Anopheles gambiae str. PEST Length = 191 Score = 89.4 bits (212), Expect = 7e-17 Identities = 58/195 (29%), Positives = 99/195 (50%), Gaps = 1/195 (0%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 MS + VVF G G+G ++ + LL +GVK + I+D+ E +L S Sbjct: 1 MSLAGQSAVVF--GGCGGMGMAIGQHLLRQGVKKLCIVDVVELTDSNLSCLKESGRDALI 58 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQ-GGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 365 D+++ +L + E G ID+++N+A ++ + K I T +I S Sbjct: 59 LCKICDISNRAALKQLLERDISEALGSIDILVNSAGIVESEVP--DKLIG---TGVINSC 113 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 L A+ +M + GGKGG ++NV+S A L +P Y A+K ++ F+ +G +S+TG Sbjct: 114 LIALNLMSRAKGGKGGVIVNVASTAGLEPIPFLPTYCASKHGLIGFTRSLGVEPVYSETG 173 Query: 546 VRVLTVCFGATDTAL 590 V+ + +C G T T + Sbjct: 174 VKFIIICPGGTRTRM 188 >UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Methanospirillum hungatei JF-1|Rep: Short-chain dehydrogenase/reductase SDR - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 249 Score = 89.0 bits (211), Expect = 9e-17 Identities = 57/200 (28%), Positives = 103/200 (51%), Gaps = 6/200 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 ++KV+ +TG + GIG+++ DEG K + + EE+ K++ E++ K G+ ++ Sbjct: 6 ENKVLLVTGGSRGIGKAIALRCADEGAKVVITWESHEESAKNVVNEIHHKNGSAMAI-QA 64 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE------VNVTALITST 365 DV +E+ ++N + E G +D+++NNA +M +++ + K E N + Sbjct: 65 DVRNEDDVKKVINKIKGEYGRLDILVNNAGIMKNNLLLMTKTEEFDLLLATNCKGPFLYS 124 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 A ++M KH K G +IN+SSV + S +Y ATKS ++ F+ + + G Sbjct: 125 RAAAKLMLKH---KSGRIINISSVVGVYGSKGQSVYSATKSFLIAFTKSLAK--ELGPFG 179 Query: 546 VRVLTVCFGATDTALLTDEK 605 + V + G DT L D K Sbjct: 180 ITVNAIAPGFIDTDLTHDVK 199 >UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: Oxidoreductase - Oceanobacillus iheyensis Length = 244 Score = 88.6 bits (210), Expect = 1e-16 Identities = 58/198 (29%), Positives = 100/198 (50%), Gaps = 6/198 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 +DKV ITG +GIG + ++ EG K I ++D+ EE G S++ EL S+ G++ F ++ Sbjct: 4 QDKVAVITGGVSGIGAATAKLFASEGAKLI-LVDMNEEKGASIEAELKSQ-GSEAIFIKA 61 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 365 DVT+EE I + G +D++ NNA + + ++K +EV++ + Sbjct: 62 DVTNEEQVKNIYTTAIDTFGKVDILFNNAGIGAVKPTEELTYAEWRKTVEVDLDGVFLVA 121 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 AI+ K G ++N +S+ S Y A K+ V+ + +G ++ Sbjct: 122 QAAIKEFLK---AGSGVIVNTASMYGWVGSPGSAAYNAAKAGVVNLTRSLGL--EYAARN 176 Query: 546 VRVLTVCFGATDTALLTD 599 +RV +C G DTA+L D Sbjct: 177 IRVNALCPGFIDTAILGD 194 >UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=16; Bacillaceae|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Bacillus anthracis Length = 264 Score = 88.2 bits (209), Expect = 2e-16 Identities = 66/212 (31%), Positives = 107/212 (50%), Gaps = 7/212 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 M+ ++KV+ ITGA++GIGE V + ++G + ++ EE K+L ++ Y Sbjct: 1 MTGRLQNKVIVITGASSGIGEQVAMQVAEQGATPV-LMARTEEKLKALADKIKETYNTPC 59 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 350 +Y DV++E + + V+QE G ID+++NNA + S+ K +VNV Sbjct: 60 YYYVLDVSEETEVQSVFSKVLQEVGRIDILVNNAGFGIFKTFEDASMDEVKDMFQVNVFG 119 Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530 L+ T + M K + G +IN++S+A + Y ATK AVL F+N + R E Sbjct: 120 LVACTKAVLPYMVKRNEGH---IINIASLAGKIATPKSSAYAATKHAVLGFTNSL-RME- 174 Query: 531 FSKTGVRVLTVCFGATDTALL-TDEKLGTFDK 623 S T V V + G DT ++ GT+ K Sbjct: 175 LSSTNVFVTAINPGPIDTNFFEIADQSGTYVK 206 >UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=3; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Pyrococcus furiosus Length = 260 Score = 87.8 bits (208), Expect = 2e-16 Identities = 59/201 (29%), Positives = 102/201 (50%), Gaps = 6/201 (2%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 K+KV +TG GIG ++ ++ + G K + + +I EEAG + L + G F ++ Sbjct: 7 KNKVAIVTGGGQGIGAAIAQLFAENGAK-VVLAEIDEEAGLEREAMLRER-GLDVTFIKT 64 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITST 365 DV DEE ++ V+ GG+D+++NNAA+M+ ++ +++ I VN+T + Sbjct: 65 DVADEESVKNMVKKTVELYGGVDILVNNAAIMSVKSIFERTLEEWERVIRVNLTGPYICS 124 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 A E M K GG +IN++S AL Y A+K +L ++ + +K Sbjct: 125 RYAAEEMIKRG---GGVIINIASTRALMSEPDTEPYSASKGGLLALTHSLA--ISLAKYR 179 Query: 546 VRVLTVCFGATDTALLTDEKL 608 +RV+ V G +T+ KL Sbjct: 180 IRVVAVSPGWIETSRWKKSKL 200 >UniRef50_Q89M15 Cluster: Dehydrogenase; n=3; Proteobacteria|Rep: Dehydrogenase - Bradyrhizobium japonicum Length = 271 Score = 87.4 bits (207), Expect = 3e-16 Identities = 58/203 (28%), Positives = 105/203 (51%), Gaps = 7/203 (3%) Frame = +3 Query: 3 LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN 182 + M+ + + KV +TG A+GIGE++V + EG IA D+ E G L + +K G Sbjct: 1 MNMAGQVEGKVALVTGGASGIGEAIVELFAREGATVIA-TDVDELRGPELAKRI-TKAGG 58 Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA-------ALMNDSIGIYKKAIEVN 341 K F DV+ EE ++ I+ + + G +D++++NA ++++ ++G ++K +N Sbjct: 59 KAIFLEQDVSSEERWIEIVAEIAKRYGRLDIMVSNAGIGIAVPSIVDMTLGDWRKQNAIN 118 Query: 342 VTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 521 + + S + +M K GG+++ +SS+A L + + Y ATK V F+ I Sbjct: 119 LDGVFLSVKHCLPLMRKTG---GGSIVMMSSLAGLRGAPGLSAYSATKGGVRLFAKSIAM 175 Query: 522 PEHFSKTGVRVLTVCFGATDTAL 590 G+RV +V G DT + Sbjct: 176 ECAAVGDGIRVNSVHPGIIDTPI 198 >UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Flavobacterium johnsoniae UW101|Rep: Short-chain dehydrogenase/reductase SDR - Flavobacterium johnsoniae UW101 Length = 269 Score = 87.4 bits (207), Expect = 3e-16 Identities = 61/190 (32%), Positives = 100/190 (52%), Gaps = 6/190 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKY-GNKTKFYR 200 KDK + ITG TGIG+++ +L+ G + + I E+ K+ ++ ++ G++ Sbjct: 30 KDKKIVITGGTTGIGKAIADVLVSLGGR-VLIFGRDEKDFKNAVADIQKQFPGSEVYGTP 88 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-----MNDSIGIYKKAIEVNVTALITST 365 +DVT +E IL E GGID++INNAAL N+S YK I+ N+T + Sbjct: 89 ADVTKKEDIQKILEIADNELGGIDILINNAALGAPGITNESYDDYKYIIDTNITGYLAFA 148 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 +A M + K G +IN+ S++A ++ IY ATKSA+ FS + + + G Sbjct: 149 QEAASRMKQQ---KSGHIINIGSMSAESKEAKSTIYVATKSAIRGFSTSLRK--ELNPLG 203 Query: 546 VRVLTVCFGA 575 ++V + GA Sbjct: 204 IKVSLIEPGA 213 >UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reductase; n=7; Bacteria|Rep: 3-ketoacyl-acyl carrier protein reductase - Leptospira interrogans Length = 254 Score = 87.0 bits (206), Expect = 4e-16 Identities = 60/203 (29%), Positives = 100/203 (49%), Gaps = 6/203 (2%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 K K +TGAA GIG+S L G ++ I D+ EE+ K+ E++ + G K + Sbjct: 5 KGKNAVVTGAARGIGKSTALTLAKAGA-NLVIADLNEESSKATADEISKQTGVKAIGIGT 63 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK------AIEVNVTALITST 365 +V+D + + A V E G +D+++NNA + D++ + K I VN+T T Sbjct: 64 NVSDVDSAAKAIQACVDEFGSVDILVNNAGITKDTLLMRMKKEQWDAVIAVNLTGTFNCT 123 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 AI+ M K+ GG++IN+SS+A + + Y A+K+ V+ F+ + K Sbjct: 124 QAAIKFMMKNP--NGGSIINLSSIAGVNGNIGQTNYSASKAGVIGFTKAVALEMASRKVR 181 Query: 546 VRVLTVCFGATDTALLTDEKLGT 614 + F AT+ EK+ T Sbjct: 182 CNAIAPGFIATEMTDAIPEKIRT 204 >UniRef50_Q2W431 Cluster: Dehydrogenase with different specificities; n=2; Magnetospirillum|Rep: Dehydrogenase with different specificities - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 248 Score = 87.0 bits (206), Expect = 4e-16 Identities = 65/212 (30%), Positives = 105/212 (49%), Gaps = 6/212 (2%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197 +++DKV ITG A+GIG V+ + + G + I DI EAG+ EL +K G K +F Sbjct: 2 KFEDKVALITGGASGIGYCTVKSMAELGA-DVLIADINVEAGEKAAAELTAK-GFKAEFV 59 Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALIT 359 R DVTD+ + + VV +G +D++ N A +++ K + +N+T I Sbjct: 60 RLDVTDKANIARVKEHVVATRGRLDILCNVAGWGHIQPFVDNDDAFIAKVMSLNLTGPIE 119 Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539 +M + GK ++NV+S A S +Y A K ++ FS + R ++ Sbjct: 120 LIRAFFPLMIEKKTGK---IVNVASDAGRVGSLGESVYSAAKGGLIAFSKALAR--EGAR 174 Query: 540 TGVRVLTVCFGATDTALLTDEKLGTFDKYLES 635 + V +C G TDT LL E +K+LE+ Sbjct: 175 FNINVNAICPGPTDTPLLKSEP----EKFLEA 202 >UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillus sp. B14905|Rep: Short chain dehydrogenase - Bacillus sp. B14905 Length = 252 Score = 86.6 bits (205), Expect = 5e-16 Identities = 57/198 (28%), Positives = 97/198 (48%), Gaps = 7/198 (3%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197 E +K+ +TGA +GIG + L G K + I+D +E G+ ++L + G + F Sbjct: 2 EHLNKIAVVTGAGSGIGRASSLKLASNGAK-VVIVDFNKETGEET-LKLVKEQGGEGIFV 59 Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALI 356 ++DV+ E +NA V+ G IDV NNA ++ + Y + + +NV + Sbjct: 60 QADVSKSEDVEKYVNAAVETYGRIDVFFNNAGVIQKISPLTEIADSEYDRIMSINVKGVF 119 Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536 I++M G G++IN +S A + H M +Y A+K AV+ + + Sbjct: 120 LGLKHVIKVM---EGQGSGSIINTASTAGVRSEHSMAVYSASKHAVIGLTKSASL--EYV 174 Query: 537 KTGVRVLTVCFGATDTAL 590 K G+R+ +C G +TAL Sbjct: 175 KKGIRINAICPGGVETAL 192 >UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=2; Actinomycetales|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Mycobacterium avium (strain 104) Length = 250 Score = 86.2 bits (204), Expect = 6e-16 Identities = 56/189 (29%), Positives = 101/189 (53%), Gaps = 4/189 (2%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV +TGAA+GIGE+ + L ++G K + + DI E+ G+ + E+ ++ G + F R+D+ Sbjct: 6 KVAVVTGAASGIGEATAKRLAEDGAK-VVVADINEDGGERVVAEI-AERGGEAAFLRTDI 63 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEV--NVTAL-ITSTLKAIE 380 + EE +++ V GG+ + NNAA+ + +++ + +V VT + + T + Sbjct: 64 SIEEDVNSLIDFAVSTYGGLHLAHNNAAVAHTPTPLHELSTDVFDTVTGIGLRGTFFCMR 123 Query: 381 IMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557 H G GG ++N +S AAL + M Y ATK ++ + G +++ G+RV Sbjct: 124 AEIAHMIGHGGGAIVNTASGAALKAAAGMHAYVATKHGIVGLTRNAGL--DYARNGIRVN 181 Query: 558 TVCFGATDT 584 V G+ T Sbjct: 182 AVAPGSIKT 190 >UniRef50_Q6XPZ7 Cluster: Short-chain dehydrogenase/reductase; n=1; Apis mellifera|Rep: Short-chain dehydrogenase/reductase - Apis mellifera (Honeybee) Length = 246 Score = 85.8 bits (203), Expect = 8e-16 Identities = 53/194 (27%), Positives = 102/194 (52%), Gaps = 9/194 (4%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 M W D+V +TGA +GIG+ ++ L+ +G+K I I ++ K+L EL SK G K Sbjct: 1 MEQNWIDEVALVTGANSGIGKCLIECLVGKGMKVIGIAPQVDKM-KTLVEELKSKPG-KL 58 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 350 + D++++ L ++ V + G ID++INNA L ND + +KK ++N+ Sbjct: 59 VPLQCDLSNQNDILKVIEWVEKNLGAIDILINNATINIDVTLQNDEVLDWKKIFDINLLG 118 Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALT---QSHVMPIYFATKSAVLQFSNCIGR 521 L + +++M K G G ++N++ + L + P Y A+K A+ ++C+ Sbjct: 119 LTCMIQEVLKLM-KKKGINNGIIVNINDASGLNLLPMNRNRPAYLASKCALTTLTDCLRS 177 Query: 522 PEHFSKTGVRVLTV 563 ++ ++V+++ Sbjct: 178 ELAQCESNIKVISI 191 >UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase bacC; n=5; Bacillus|Rep: Bacilysin biosynthesis oxidoreductase bacC - Bacillus subtilis Length = 253 Score = 85.4 bits (202), Expect = 1e-15 Identities = 61/194 (31%), Positives = 101/194 (52%), Gaps = 6/194 (3%) Frame = +3 Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206 DK V ITG A+GIG + V+ L + ++ + DI E G+++ + N+ ++ F ++D Sbjct: 5 DKTVLITGGASGIGYAAVQAFLGQQA-NVVVADIDEAQGEAMVRKENN---DRLHFVQTD 60 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTL 368 +TDE + + V GG+DV+INNA + + + K ++VN+T + + Sbjct: 61 ITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSK 120 Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 A++ M + GK G +IN SV L +P Y A+K VLQ + + ++K + Sbjct: 121 HALKHM--LAAGK-GNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMA--VDYAKHQI 175 Query: 549 RVLTVCFGATDTAL 590 RV VC G DT L Sbjct: 176 RVNCVCPGIIDTPL 189 >UniRef50_P91615 Cluster: Alcohol dehydrogenase-related 31 kDa protein; n=44; Drosophiliti|Rep: Alcohol dehydrogenase-related 31 kDa protein - Drosophila melanogaster (Fruit fly) Length = 272 Score = 85.0 bits (201), Expect = 1e-15 Identities = 58/201 (28%), Positives = 100/201 (49%), Gaps = 1/201 (0%) Frame = +3 Query: 60 GIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVT-DEEHFLGI 236 GI ++L+ + + +AIL E Q++ + K + F+ DVT E Sbjct: 17 GIALETSKVLMTKNIAKLAILQSTENPQAIAQLQ-SIKPSTQIFFWTYDVTMAREDMKKY 75 Query: 237 LNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKHSGGKGGT 416 + V+ + IDV+IN A L +++ I N+T ++ + + M + GG GG Sbjct: 76 FDEVMVQMDYIDVLINGATLCDENN--IDATINTNLTGMMNTVATVLPYMDRKMGGTGGL 133 Query: 417 VINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCFGATDTALLT 596 ++NV+SV L S V Y A+K V+ F+ + P ++S+ GV V+ VC G T + Sbjct: 134 IVNVTSVIGLDPSPVFCAYSASKFGVIGFTRSLADPLYYSQNGVAVMAVCCG--PTRVFV 191 Query: 597 DEKLGTFDKYLESSCLDQLKK 659 D +L F +Y +S D+L++ Sbjct: 192 DRELKAFLEYGQSFA-DRLRR 211 >UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Sphingomonadales|Rep: Short-chain dehydrogenase/reductase SDR - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 285 Score = 84.6 bits (200), Expect = 2e-15 Identities = 59/189 (31%), Positives = 90/189 (47%), Gaps = 4/189 (2%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV +TGAA+GIG++ V L EG H+ DI E G++L N + F R DV Sbjct: 6 KVAVVTGAASGIGKATVLKLAGEGA-HVFAADIDEAGGRALADASNGRID----FVRCDV 60 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK---KAIEVNVTALITSTLKAIE 380 T +++A + GGID+V NNAA D I + + + + ++ S I Sbjct: 61 TVPSDIEALMDAAAAKAGGIDIVFNNAAAGGDRAPIDEITPEGWDATMDLVLKSVAMGIR 120 Query: 381 IMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557 H G KG +++N +SVAAL + Y K+ VL + ++ G+RV Sbjct: 121 YAAPHMKGRKGASIVNTASVAALGAGYSPTAYAVAKAGVLHLTRVAA--TDLAQYGIRVN 178 Query: 558 TVCFGATDT 584 +C G +T Sbjct: 179 AICPGFINT 187 >UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Short-chain dehydrogenase/reductase SDR precursor - Herpetosiphon aurantiacus ATCC 23779 Length = 247 Score = 84.6 bits (200), Expect = 2e-15 Identities = 57/195 (29%), Positives = 102/195 (52%), Gaps = 7/195 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV +TG A GIG + ++L +G + I DI E+ G + ++ G + F DV Sbjct: 5 KVAIVTGGAIGIGAATAQLLAKQGAI-VVIGDINEQTGLATVEQIRGNAG-QAYFRHCDV 62 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALITSTL 368 + E ++ + +QGG+D++INNA + ++ ++ +++++T + Sbjct: 63 SHEADIQALVQFAL-DQGGLDIMINNAGIGGKPAPLHLTENHNWQRVLDIDLTGVFWGQK 121 Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 A + M +GGKGG ++NV+S+A + S + Y K+ V+Q S G E + G+ Sbjct: 122 YASQAM--LAGGKGGAIVNVASIAGVAGSPNLGPYGVAKAGVIQMSK-TGAIE-LASAGI 177 Query: 549 RVLTVCFGATDTALL 593 R+ VC G T+TA+L Sbjct: 178 RINAVCPGWTETAIL 192 >UniRef50_Q89KQ8 Cluster: Blr4846 protein; n=2; Proteobacteria|Rep: Blr4846 protein - Bradyrhizobium japonicum Length = 255 Score = 83.4 bits (197), Expect = 4e-15 Identities = 55/170 (32%), Positives = 87/170 (51%), Gaps = 5/170 (2%) Frame = +3 Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206 D+VV ITG A+GIG + VR +G + +A LDI E AG SL E+ + G F R D Sbjct: 11 DRVVLITGGASGIGAAFVRAFAAQGAR-VAFLDIDEAAGGSLVEEVAAASGAAPLFVRCD 69 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI--- 377 + D + + V G V++NNAA ND + + +I LK + Sbjct: 70 LLDIDALRAAIAQVRGSLGDAAVLVNNAA--NDQRQVLAEVTPSEFDWMIGVNLKHVFFA 127 Query: 378 --EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 521 ++ + GG++IN+SS+A + +P+Y A K+A++ F+N + R Sbjct: 128 AQAVVPQMQARGGGSIINMSSIAWMRGGPALPVYAAAKAAIVGFTNSLAR 177 >UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 251 Score = 83.4 bits (197), Expect = 4e-15 Identities = 61/203 (30%), Positives = 98/203 (48%), Gaps = 6/203 (2%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV ITG A G GE+ R + EG + + I D+ +EAG+ + EL G+ +F DV Sbjct: 7 KVALITGGARGQGEAEARRFVAEGAR-VVIADVLDEAGQRVAAEL----GDAARFQHLDV 61 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 371 T E + ++A + + G +D+++NNAA++ S+ Y+K I+VN Sbjct: 62 TREADWQIAVDATLAQFGRLDILVNNAAILKLVPIEACSLDDYRKVIDVNQVGCWLGMKS 121 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 A +G GG+++NVSS A + Y ++K AV + F + G+R Sbjct: 122 A---LGALKAAGGGSIVNVSSTAGMEGVAGGSAYVSSKFAVRGMTKAAAL--EFGRYGIR 176 Query: 552 VLTVCFGATDTALLTDEKLGTFD 620 V +V G DT + + FD Sbjct: 177 VNSVHPGGIDTVMARPPEFADFD 199 >UniRef50_P00334 Cluster: Alcohol dehydrogenase; n=485; Drosophilidae|Rep: Alcohol dehydrogenase - Drosophila melanogaster (Fruit fly) Length = 256 Score = 83.4 bits (197), Expect = 4e-15 Identities = 57/189 (30%), Positives = 93/189 (49%), Gaps = 2/189 (1%) Frame = +3 Query: 33 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVE-LNSKYGNKTKFYRSDV 209 V+F+ G GIG + LL +K++ ILD E +++ +N K FY DV Sbjct: 10 VIFVAGLG-GIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKV--TVTFYPYDV 66 Query: 210 TDE-EHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 386 T +L + + +DV+IN A +++D ++ I VN T L+ +T ++ Sbjct: 67 TVPIAETTKLLKTIFAQLKTVDVLINGAGILDDHQ--IERTIAVNYTGLVNTTTAILDFW 124 Query: 387 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 566 K GG GG + N+ SV + +P+Y TK+AV+ F++ + + TGV TV Sbjct: 125 DKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPI--TGVTAYTVN 182 Query: 567 FGATDTALL 593 G T T L+ Sbjct: 183 PGITRTTLV 191 >UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Leptospira interrogans Length = 256 Score = 82.6 bits (195), Expect = 8e-15 Identities = 61/204 (29%), Positives = 101/204 (49%), Gaps = 7/204 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 M + KDKV +TG +TGIG++VV+ + +GVK + E GK L+ E+ ++ G Sbjct: 1 MENIMKDKVAIVTGGSTGIGKAVVKEFVSKGVK-VVFCGRRLEEGKKLESEIRAE-GGDV 58 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSI-----GIYKKAIEVNVT 347 F DVT E +++A +++ G +D INNA +M N + ++ K + VN+ Sbjct: 59 YFVVCDVTSGEQVKKVVDAALEKFGRLDFGINNAGIMGLNHLLHEYPEDVWDKVVNVNLK 118 Query: 348 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527 S I M K GG V+NVSS++ + + Y A K V+ + Sbjct: 119 GTWLSMKYQIPEMIKMG---GGVVVNVSSISGINGVVGINPYAAAKHGVVGLTKSAAL-- 173 Query: 528 HFSKTGVRVLTVCFGATDTALLTD 599 ++K +R+ +C GA T +L + Sbjct: 174 EYAKKNIRINAICPGAVKTEILDE 197 >UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1; Psychroflexus torquis ATCC 700755|Rep: 3-oxoacyl-[ACP] reductase - Psychroflexus torquis ATCC 700755 Length = 251 Score = 82.6 bits (195), Expect = 8e-15 Identities = 63/193 (32%), Positives = 103/193 (53%), Gaps = 2/193 (1%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 M + K K ITG + GIG+S+ L +EGV +IAI +EA + + EL K G K Sbjct: 1 MDLQLKGKNAIITGGSKGIGKSIALHLAEEGV-NIAICARGKEALQKTKNELLEK-GVKV 58 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITS 362 DV D E F L AV E G +D+++NNA+ M D ++ ++++++ A + + Sbjct: 59 FTQTCDVGDSEQFNLFLTAVKNEFGSVDILVNNASALTMGDEYQDWEASLQIDLMASVRA 118 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 T K + M + SG G ++ +SSV+ L +S P Y A K+A++ +S + + Sbjct: 119 TKKVVPWMSE-SG--SGNILFISSVSGL-ESGSPPAYAAAKAALISYSKTMA--VQLAPQ 172 Query: 543 GVRVLTVCFGATD 581 +RV T+ GA + Sbjct: 173 HIRVNTIAPGAIE 185 >UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caulobacter sp. K31|Rep: Short-chain dehydrogenase/reductase SDR - Caulobacter sp. K31 Length = 277 Score = 82.6 bits (195), Expect = 8e-15 Identities = 56/193 (29%), Positives = 100/193 (51%), Gaps = 6/193 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K+ +TGAA G+G ++ + L+EG + + D++EE EL + + R DV Sbjct: 9 KIAIVTGAARGLGAAIAKRYLEEGAT-VVLADLSEEKTTERAAELGAGAHGR----RCDV 63 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 371 D E F +++A V E G +D+++NNA + S+ + + VNV+++ Sbjct: 64 GDWEAFSTLIDATVAEFGRLDILVNNAGINRAGLVPGFSLQHWDDLLRVNVSSVFYGCRA 123 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 AI M + GG +INV+S+A L + Y A+K+AV+ F+ + +H + +R Sbjct: 124 AIPHMRRQGGG---AIINVASIAGLRGETLAAAYSASKAAVVNFTRSLAL-DH-ADENIR 178 Query: 552 VLTVCFGATDTAL 590 V +C G+ +T + Sbjct: 179 VNAICPGSVETEM 191 >UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR; n=6; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1 Length = 260 Score = 82.6 bits (195), Expect = 8e-15 Identities = 59/206 (28%), Positives = 101/206 (49%), Gaps = 7/206 (3%) Frame = +3 Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206 +K + ITG A+GIG + ++L G K I I D+AE+ G +L + + + F + D Sbjct: 14 NKRILITGGASGIGAASAKLLASRGAK-IIIADLAEDLGHALAQQAWAS-DHTINFMKVD 71 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-------KAIEVNVTALITST 365 VT + V++ GG+DVVINNA + + +++ + + VNV + Sbjct: 72 VTQAAEVNALFAYAVEQLGGLDVVINNAGVDHPPAPLHQLTEDDFDRCMTVNVKGVWHCM 131 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 AI + H GG VINV+S+A L + ++ Y A+K AV+ + +++ Sbjct: 132 RAAIACLSPHGGGH---VINVASIAGLRSAPMLSAYSASKHAVIGLTK--SAAIEYARAN 186 Query: 546 VRVLTVCFGATDTALLTDEKLGTFDK 623 +R VC DT ++ + L +K Sbjct: 187 IRFNAVCPSFIDTPMVRNSMLNMNEK 212 >UniRef50_P54398 Cluster: Fat body protein 2; n=6; Schizophora|Rep: Fat body protein 2 - Drosophila melanogaster (Fruit fly) Length = 256 Score = 82.6 bits (195), Expect = 8e-15 Identities = 55/194 (28%), Positives = 97/194 (50%), Gaps = 2/194 (1%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE--EAGKSLQVELNSKYGNKTK 191 +W K V G+ +GIG ++ L+ + +K + I+ E E K LQ +N K Sbjct: 3 DWTGKNVVYVGSFSGIGWQMMMQLMQKDIKMMGIMHRMENVEMMKKLQA-INPSV--KVV 59 Query: 192 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 371 F + ++ ++ + + Q G IDV+IN ++ D + + +N+T +I ST+ Sbjct: 60 FMQMNLMEKMSIEQAMKKMGQMMGHIDVMINGEGVLLDKD--VETTMGMNLTGMIQSTMM 117 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 A+ M K G GG V+N+SSV L + +Y A +L F+ +G + KTGV Sbjct: 118 AMPYMDKTQMGMGGMVVNMSSVYGLEPAPAFAVYAAAMHGILGFTRSMGDKMIYQKTGVM 177 Query: 552 VLTVCFGATDTALL 593 + +C G T++ ++ Sbjct: 178 FMAMCPGLTNSEMI 191 >UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Bacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Pseudomonas putida (strain KT2440) Length = 262 Score = 82.2 bits (194), Expect = 1e-14 Identities = 57/224 (25%), Positives = 105/224 (46%), Gaps = 7/224 (3%) Frame = +3 Query: 3 LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN 182 + +++++ KVV +TGA +GIG + G +A+ DI+ + G VEL G Sbjct: 1 MTVNYDFSGKVVLVTGAGSGIGRATALAFAQSGAS-VAVADISTDHGLKT-VELVKAEGG 58 Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVN 341 + F+ DV E +L VV GG+D+ NNA + + + + +++ I+VN Sbjct: 59 EATFFHVDVGSEPSVQSMLAGVVAHYGGLDIAHNNAGIEANIVPLAELDSDNWRRVIDVN 118 Query: 342 VTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 521 ++++ I +M K GG ++N +S + L + + Y ATK V+ + Sbjct: 119 LSSVFYCLKGEIPLMLKRG---GGAIVNTASASGLIGGYRLSGYTATKHGVVGLTKAAA- 174 Query: 522 PEHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQL 653 ++ +R+ VC G D+ L D D+ L + + +L Sbjct: 175 -IDYANQNIRINAVCPGPVDSPFLADMPQPMRDRLLFGTPIGRL 217 >UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyces avermitilis|Rep: Putative dehydrogenase - Streptomyces avermitilis Length = 258 Score = 81.8 bits (193), Expect = 1e-14 Identities = 59/199 (29%), Positives = 104/199 (52%), Gaps = 6/199 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 +VV I+GAA G GE R+ ++EG K + + D+ ++ G++L E+ ++Y DV Sbjct: 7 RVVLISGAARGQGEQEARLFVEEGAK-VVVADVLDDQGEALAKEIGARY------VHLDV 59 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGI----YKKAIEVNVTALITSTLK 371 E+ + + G ID ++NNA ++ ND +G +++ ++VN + +K Sbjct: 60 GREDDWQAAVTVAKDAYGHIDGLVNNAGILRFNDLVGTPLAEFQQIVQVNQVGVFLG-IK 118 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 + + +G GGT++N +S A LT + Y ATK A++ + + E +K +R Sbjct: 119 TVAPEIEAAG--GGTIVNTASYAGLTGMAYVGAYTATKHAIVGLTR-VAALELAAKK-IR 174 Query: 552 VLTVCFGATDTALLTDEKL 608 V VC GA DTA+ +L Sbjct: 175 VNAVCPGAIDTAMSNPSQL 193 >UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3; Bacillus|Rep: Cyclohexanol dehydrogenase - Bacillus sp. SG-1 Length = 279 Score = 81.8 bits (193), Expect = 1e-14 Identities = 54/197 (27%), Positives = 98/197 (49%), Gaps = 7/197 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 ++K ITGA +G+G+S L EG+ IA++DI EE G VE+ + G F ++ Sbjct: 31 ENKAAIITGAGSGLGQSAAVRLAKEGI-DIAVVDINEEGGNE-TVEMVKQKGVNAIFIKA 88 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNVTALITS 362 DV+ E ++ V+E G +D NNA + +N I ++ + +N+ + Sbjct: 89 DVSKAEEVKNYVDKTVEEFGKVDYFFNNAGISGSGQYFLNTEIEEIEQVVSINLMGALYG 148 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 E+M K+ GG+++N +S A + + Y ATK ++ + + ++K Sbjct: 149 VRYVAEVMMKNG---GGSIVNTASSAGVIGQDSVVTYSATKHGIIGLTKSM--VAEYAKE 203 Query: 543 GVRVLTVCFGATDTALL 593 G+RV + G T+T ++ Sbjct: 204 GLRVNAIAPGPTETPMV 220 >UniRef50_Q6UWP2 Cluster: Dehydrogenase/reductase SDR family member 11 precursor; n=30; Euteleostomi|Rep: Dehydrogenase/reductase SDR family member 11 precursor - Homo sapiens (Human) Length = 260 Score = 81.8 bits (193), Expect = 1e-14 Identities = 59/199 (29%), Positives = 99/199 (49%), Gaps = 11/199 (5%) Frame = +3 Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--KSLQVELNSK-YGNKTK 191 W+D++ +TGA+ GIG +V R L+ +G+K ++ A G + L E S Y Sbjct: 9 WRDRLALVTGASGGIGAAVARALVQQGLK---VVGCARTVGNIEELAAECKSAGYPGTLI 65 Query: 192 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTAL 353 YR D+++EE L + +A+ + G+D+ INNA L++ S +K VNV AL Sbjct: 66 PYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLAL 125 Query: 354 ITSTLKAIEIMGKHSGGKGGTVINVSSVAA--LTQSHVMPIYFATKSAVLQFSNCIGRPE 527 T +A + M K G +IN++S++ + V Y ATK AV + + + Sbjct: 126 SICTREAYQSM-KERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQEL 184 Query: 528 HFSKTGVRVLTVCFGATDT 584 ++T +R + G +T Sbjct: 185 REAQTHIRATCISPGVVET 203 >UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 258 Score = 81.4 bits (192), Expect = 2e-14 Identities = 55/190 (28%), Positives = 97/190 (51%), Gaps = 3/190 (1%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV +TG A G+G + R+ + EG + I D+ + G++L EL G+ +F R DV Sbjct: 7 KVAIVTGGARGMGAATCRLFVAEGAC-VVIGDVLDAEGEALAREL----GDAARFMRLDV 61 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGIYKKAIEVNVTALITSTLKAIEI 383 DE +++ + +A +++ G IDV++NNAA++ + K+ E V+ + T I Sbjct: 62 ADEANWVRVTDATMEQFGRIDVLVNNAAVLTFGGITELSKRDFERAVSINLVGTFVGIRT 121 Query: 384 MGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560 + H K G+++N+SSV L + + Y ++K V + GVRV + Sbjct: 122 IAPHMIAQKSGSIVNISSVDGLRGVNALAAYVSSKWGVRGLTKVAAL--ELGHQGVRVNS 179 Query: 561 VCFGATDTAL 590 + G +TA+ Sbjct: 180 IHPGGVNTAM 189 >UniRef50_Q28GY1 Cluster: Novel protein containing short chain dehydrogenase domain; n=4; Deuterostomia|Rep: Novel protein containing short chain dehydrogenase domain - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 255 Score = 81.0 bits (191), Expect = 2e-14 Identities = 60/197 (30%), Positives = 96/197 (48%), Gaps = 9/197 (4%) Frame = +3 Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-Y 197 WK +V +TGA+ GIG +V R+L+ G+K + ++ K L E S T F Y Sbjct: 4 WKGRVALVTGASVGIGAAVARVLVQHGMKVVGCARSVDKIEK-LAAECQSAGYPGTLFPY 62 Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALIT 359 + D+++EE L + +A+ G+DV INNA L++ ++ I+VNV AL Sbjct: 63 KCDLSNEEEILSMFSAIKTLHQGVDVCINNAGLARPEPLLSGKTEGWRTMIDVNVLALSI 122 Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYF--ATKSAVLQFSNCIGRPEHF 533 T +A + M K G +IN++SV +F ATK V + I + Sbjct: 123 CTREAYQSM-KERNIDDGHIININSVLGHIYQCAKQAHFYCATKHTVTALTEAIRQELRE 181 Query: 534 SKTGVRVLTVCFGATDT 584 K+ +RV ++ G +T Sbjct: 182 LKSHIRVTSISPGLVET 198 >UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=1; Hyphomonas neptunium ATCC 15444|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Hyphomonas neptunium (strain ATCC 15444) Length = 262 Score = 81.0 bits (191), Expect = 2e-14 Identities = 53/192 (27%), Positives = 93/192 (48%), Gaps = 2/192 (1%) Frame = +3 Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200 +++KV ITGAA+GIG + R+L EG H+ + D+ + GKS+ +L G + Sbjct: 6 FENKVAVITGAASGIGAATARLLAREGA-HVVLADVNDNGGKSIAADL----GPTAMAVK 60 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSIGIYKKAIEVNVTALITSTLKA 374 DV+ ++ A V+ G ID++ NNA + S+ I E + + S A Sbjct: 61 CDVSSAAEVEALVKAAVERHGRIDILFNNAGIGSFGTSVEIQPAEWERVIAIDLHSVYYA 120 Query: 375 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554 H +G ++N +S++ L + Y A K AV+ ++ + +H + G+RV Sbjct: 121 CHFAIPHM-PRGSAIVNTASISGLGGDYRFAAYNAAKGAVVNYTRALA-VDH-GRDGIRV 177 Query: 555 LTVCFGATDTAL 590 +C G +T + Sbjct: 178 NALCPGLVETPI 189 >UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Parvibaculum lavamentivorans DS-1 Length = 268 Score = 80.6 bits (190), Expect = 3e-14 Identities = 56/197 (28%), Positives = 95/197 (48%), Gaps = 9/197 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV +TGAA GIG + + L EG K + D E G+ + E+ + G T F+R DV Sbjct: 7 KVAIVTGAAKGIGAATAKALAREGAK-VVCSDFDAENGQVVADEIAGEGGTAT-FFRHDV 64 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITSTL 368 TDE + ++ ++ GG+ VV+NNA + + ++ ++ IEV++ ++ Sbjct: 65 TDEAQWEAVVKLAEEKFGGLHVVVNNAGIAPEAGPIEEKTLADWRHTIEVDLDSVFLGCK 124 Query: 369 KAIEIMGKHS--GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 I + K++ GG GG ++N+SS+ L Y A K V + + Sbjct: 125 HGIRTIKKYTSKGGAGGAIVNISSILGLVGQSGASDYNAAKGGVRLLTKSAALECADAGY 184 Query: 543 GVRVLTVCFGATDTALL 593 +RV +V G DT ++ Sbjct: 185 NIRVNSVHPGYIDTPMV 201 >UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325; n=2; Thermotoga|Rep: Uncharacterized oxidoreductase TM_0325 - Thermotoga maritima Length = 251 Score = 80.6 bits (190), Expect = 3e-14 Identities = 62/194 (31%), Positives = 95/194 (48%), Gaps = 6/194 (3%) Frame = +3 Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200 ++ KVV ITGA +GIG+ + + G K +AI DI+EE GK VEL G + F Sbjct: 3 FQGKVVLITGAGSGIGKKAAVMFAERGAK-VAINDISEEKGKE-TVELIKSMGGEAAFIF 60 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITS 362 DV + I+ V+ G +D+++NNA ++ S + K + VNV Sbjct: 61 GDVAKDAE--QIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFLL 118 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 + A+E M K GG ++NVSS A L +Y +K+A+L + + + Sbjct: 119 SKYAVEQMKKQG---GGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLA--VDYVDY 173 Query: 543 GVRVLTVCFGATDT 584 G+RV VC G T + Sbjct: 174 GIRVNAVCPGTTQS 187 >UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=1; Bacillus halodurans|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Bacillus halodurans Length = 247 Score = 80.2 bits (189), Expect = 4e-14 Identities = 55/222 (24%), Positives = 105/222 (47%), Gaps = 10/222 (4%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 +DKV +TGA GIG+ +V+ +++G I EA + ++ LN G K Y S Sbjct: 4 RDKVAIVTGATRGIGKEIVKTFVEQGAFVYGIYASNHEAAREIEKTLNQ--GEKCVSYVS 61 Query: 204 DVTDEEHFL-GILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 362 D++ F+ + +VV + +D+++NNA + D +++ ++VN T Sbjct: 62 GSVDDQLFIHSLFKSVVDKHNRLDILVNNAGITRDQFLFQMDDQSWQQVLQVNFGGTYTC 121 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 A+ M + GK ++NV SV + Y A+K A++ + + R +S+ Sbjct: 122 CHAALPYMERKKQGK---IVNVVSVTGVVGREAQTNYGASKGAIIGLTRLLAR--KYSEK 176 Query: 543 GVRVLTVCFGATDTALL---TDEKLGTFDKYLESSCLDQLKK 659 G+ + + G +T ++ +EKL F ++ + L K+ Sbjct: 177 GISINAIAPGMIETEMIKQVPEEKLKNFLRFTNAKKLGSTKE 218 >UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Chloroflexus|Rep: Short-chain dehydrogenase/reductase SDR - Chloroflexus aggregans DSM 9485 Length = 256 Score = 80.2 bits (189), Expect = 4e-14 Identities = 60/198 (30%), Positives = 98/198 (49%), Gaps = 6/198 (3%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197 E++ KV +TG A GIG + L EG + I D + A + VE + +G + Sbjct: 2 EFQGKVAIVTGGAQGIGRATALALAREGAA-VVIAD-RDAAATTALVEGINAWGGRALAV 59 Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALIT 359 +DV+DE I N V E GGID+++NNA + + ++ ++++ I VN+T + Sbjct: 60 IADVSDESDAARIANDTVLEFGGIDLLVNNAGIQQPGTIESTTLQLWQEIINVNLTGVF- 118 Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539 L + +M + GG ++NV+SV L Y A+K V+ + + + Sbjct: 119 --LVSRFVMPELRRRGGGAIVNVASVYGLRAEAGWAAYAASKGGVIALTRAMALDG--AP 174 Query: 540 TGVRVLTVCFGATDTALL 593 G+RV VC G DT+LL Sbjct: 175 DGIRVNCVCPGLIDTSLL 192 >UniRef50_Q8YQR6 Cluster: All3753 protein; n=6; Bacteria|Rep: All3753 protein - Anabaena sp. (strain PCC 7120) Length = 263 Score = 79.8 bits (188), Expect = 6e-14 Identities = 60/192 (31%), Positives = 94/192 (48%), Gaps = 6/192 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 + ITGAA+GIG +V I + ++ ++D A+E + + +E K+G K D+ Sbjct: 7 QTALITGAASGIGYELVCIFAENDY-NLVLVDRAKEKLEEIAIEFQDKFGISVKPIVRDL 65 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA-----LMNDS-IGIYKKAIEVNVTALITSTLK 371 + I V Q +DV++NNA L ND+ + + ++VNV T Sbjct: 66 SKTTSPEEIFQEVEQANIKVDVLVNNAGFGTYGLFNDTNLTDELEMLQVNVVCTTHLTKL 125 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 ++ M + GK ++NVSS AA +M +YFATK+ VL FS + TGV Sbjct: 126 FLKNMVQQGEGK---ILNVSSAAAFQPGPLMAVYFATKAYVLSFSEALA--NELDGTGVT 180 Query: 552 VLTVCFGATDTA 587 V +C G T +A Sbjct: 181 VTVLCPGTTQSA 192 >UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2; Actinomycetales|Rep: Short chain dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 267 Score = 79.8 bits (188), Expect = 6e-14 Identities = 58/190 (30%), Positives = 93/190 (48%), Gaps = 7/190 (3%) Frame = +3 Query: 42 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTDEE 221 +TG A G+G + L D G + I D+ EE G++ + K G T F + DVTD+ Sbjct: 13 VTGGAKGLGAGMAAALADAGAA-VVIGDVLEEEGRATADSVG-KTGVDTGFVKLDVTDDG 70 Query: 222 HFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLKAIEI 383 ++ + A V++ GG+D+++NNA + S+ + ++ EVN+ + + Sbjct: 71 NWERAVAATVEQLGGLDLLVNNAGIEISSLVVDIDPADIRRMCEVNILGVALGLKHGLRA 130 Query: 384 MGK-HSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560 M + G GG ++NVSSVAA + Y ATKSAV + + + GVRV Sbjct: 131 MRPGGAAGSGGAIVNVSSVAATIPFPGIAGYSATKSAVDRLTRVAAQEAGKLGYGVRVNC 190 Query: 561 VCFGATDTAL 590 V G T + Sbjct: 191 VYPGLVATEM 200 >UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Leeuwenhoekiella blandensis MED217 Length = 257 Score = 79.8 bits (188), Expect = 6e-14 Identities = 49/167 (29%), Positives = 88/167 (52%), Gaps = 6/167 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 K+KV +TG A+G+G+S ++L EG K I + DI EE GK + V+ + G + F + Sbjct: 5 KNKVAIVTGGASGLGKSSAKLLAREGAK-IVVSDIDEEGGKKV-VQQIKEDGGEAIFIKQ 62 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL-----MND-SIGIYKKAIEVNVTALITST 365 DV E+ + ++ ++ G + ++ N+A + + D ++ +K I++N+ T Sbjct: 63 DVAKEDEWKNVIETTLETYGKLHILANSAGIGLGGTVEDVTLEDWKNLIDINLNGTFLGT 122 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 506 I+ G +GG++IN SS+ L +P Y A+K V F+ Sbjct: 123 KYGIK--GMRKTDEGGSIINFSSIEGLIGDPNLPAYNASKGGVTIFT 167 >UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419; n=15; Staphylococcus|Rep: Uncharacterized oxidoreductase SSP0419 - Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 /DSM 20229) Length = 234 Score = 79.8 bits (188), Expect = 6e-14 Identities = 59/209 (28%), Positives = 105/209 (50%), Gaps = 7/209 (3%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAI-LDIAEEAGKSLQVELNSKYGNKTKF 194 E +DKV +TGA++GIG S+ L ++GVK + D + A + +++ N + +T Sbjct: 3 ELQDKVAVVTGASSGIGASIAETLANQGVKVVLTGRDESRLAEVAKRIQDNKQAVVETSI 62 Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALI 356 DVT +E ++ ++ G ID+++N+A LM S + ++ I+VN+ + Sbjct: 63 V--DVTHKEEVTELVEKTKEKFGQIDILVNSAGLMLSSAITEGDVEAWEAMIDVNIKGTL 120 Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536 + + M S G +IN++S++ + +Y A+K+AV + G + + Sbjct: 121 YTINAVLPSMLNQSSGH---IINIASISGFEVTKKSTLYSASKAAVHSITQ--GLEKELA 175 Query: 537 KTGVRVLTVCFGATDTALLTDEKLGTFDK 623 KTGVRV ++ G DT L D G K Sbjct: 176 KTGVRVTSISPGMVDTPLSGDTDWGARKK 204 >UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4; Brucellaceae|Rep: GLUCOSE 1-DEHYDROGENASE II - Brucella melitensis Length = 272 Score = 79.4 bits (187), Expect = 7e-14 Identities = 58/197 (29%), Positives = 95/197 (48%), Gaps = 6/197 (3%) Frame = +3 Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200 +KDKVV +TG A+GIGE+ R + EG K + I D ++ G+ L EL + + F + Sbjct: 3 FKDKVVIVTGGASGIGEATARAFIREGAK-VVIADFSDH-GQQLADELAGAH-EQALFIK 59 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITS 362 +DV D ++ V+ G +D++ NA + D+ ++K I++N+T + Sbjct: 60 TDVADTRAVQALIARTVENYGRLDIMFANAGIAADAPIDELDEAAWQKTIDINLTGVYLC 119 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 AI+ M S G GG ++N S+ + + Y A K V + + + Sbjct: 120 DKYAIDQM--RSQG-GGVIVNCGSIHSHVGKSGVTAYAAAKGGVKLLTQTLA--IDYGPQ 174 Query: 543 GVRVLTVCFGATDTALL 593 +RV VC G DT LL Sbjct: 175 NIRVNAVCPGYIDTPLL 191 >UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep: CylG - Streptococcus agalactiae Length = 240 Score = 79.4 bits (187), Expect = 7e-14 Identities = 53/197 (26%), Positives = 96/197 (48%), Gaps = 7/197 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV +TG GIG ++ + L EG K IAI + + ++LQ EL K Y+ ++ Sbjct: 2 KVAIVTGGTRGIGRAITKELYKEGYKVIAIYNSNDAKARALQEEL-----PKLDVYKCNI 56 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 371 +D + ++ + +E GGID ++NNA ++ D + + I +N+ L+ + Sbjct: 57 SDAKAVQKLVTKIFREYGGIDCLVNNAGIVRDGFFLMMSKEKWMDVININIMGLVNMSKA 116 Query: 372 AIEIM-GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 ++IM K GK VIN+SS + + Y ATK A++ + + + F+ G+ Sbjct: 117 VLKIMKAKRIQGK---VINISSTSGIAGQIGQANYSATKGAIISITKTLAK--EFASDGI 171 Query: 549 RVLTVCFGATDTALLTD 599 + V G +T + + Sbjct: 172 TINCVSPGFIETDMTNE 188 >UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacteria|Rep: Cyclopentanol dehydrogenase - Comamonas sp. (strain NCIMB 9872) Length = 250 Score = 79.4 bits (187), Expect = 7e-14 Identities = 52/166 (31%), Positives = 84/166 (50%), Gaps = 6/166 (3%) Frame = +3 Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206 DKVV +TG A G+G + +L EG + + D+ EE G E+ + G K F D Sbjct: 6 DKVVLVTGGAMGMGLTHCTLLAREGAT-VYLSDMNEELGHQAVAEIR-RQGGKAHFLHLD 63 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 368 VT+E H+ G ++ ++ E +D ++NNA ++ + S + + E+NV ++ T Sbjct: 64 VTNENHWTGAVDTILAESDRLDALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTR 123 Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 506 IE M K G ++NVSS+ L + Y A+K AV F+ Sbjct: 124 AVIEPMRK---AHKGCIVNVSSIYGLVGAPGAAAYEASKGAVRLFT 166 >UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=9; Firmicutes|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Oceanobacillus iheyensis Length = 253 Score = 79.0 bits (186), Expect = 1e-13 Identities = 51/201 (25%), Positives = 102/201 (50%), Gaps = 7/201 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 KDKV +TGAA+G+G+++ + EG K + + D+ EE +S+ E+ S G T + Sbjct: 4 KDKVAIVTGAASGMGKAIATLYASEGAK-VIVADLNEEGAQSVVEEITSNNGVATAI-KV 61 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN--DSIG-----IYKKAIEVNVTALITS 362 ++ +E +++ V G +D+++NNA +M+ +++G + ++N ++ + Sbjct: 62 NIAQKEDIDKMIDTAVDTYGTLDILVNNAGIMDGFEAVGDVEDDRWDLIFDINTKGVMRA 121 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 KAI I + + G ++N +S L +H Y A+K AV+ + G ++ + Sbjct: 122 MRKAIPIFLEK---ESGVIVNTASTGGLNGAHAGAAYGASKHAVIGLTKNTG--YMYANS 176 Query: 543 GVRVLTVCFGATDTALLTDEK 605 G+R + G T + + K Sbjct: 177 GIRCNAIAPGGVATNITSSLK 197 >UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductase; n=3; Lactobacillales|Rep: 3-oxoacyl-acyl carrier protein reductase - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 249 Score = 79.0 bits (186), Expect = 1e-13 Identities = 58/205 (28%), Positives = 102/205 (49%), Gaps = 8/205 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 M+ KDKV ITG GIG + + EG K + + + G++ +K+G+ Sbjct: 1 MTDRLKDKVAIITGGVAGIGLGIAECYVREGAKVVVTANHNVDGGRAAV----AKFGDDV 56 Query: 189 K-FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSI-----GIYKKAIEVNV 344 F + DV+ E + +++A + + G +D+++NNA + +N +I ++K I+VN+ Sbjct: 57 SLFVQQDVSKEADWQKVIDATIAKFGRVDILVNNAGIGGVNTAIEDLDLADWQKVIDVNL 116 Query: 345 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 524 TA AI+ M K + G++INVSSVA L + P Y A+K ++ Sbjct: 117 TANFLGEKAAIKAM-KQTADAKGSIINVSSVAGLVGLPMAPAYSASKGGSRLLTHATALN 175 Query: 525 EHFSKTGVRVLTVCFGATDTALLTD 599 +RV +V G DT+++ + Sbjct: 176 LAQRGIDIRVNSVHPGWIDTSIVPE 200 >UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR - Solibacter usitatus (strain Ellin6076) Length = 275 Score = 79.0 bits (186), Expect = 1e-13 Identities = 59/196 (30%), Positives = 97/196 (49%), Gaps = 6/196 (3%) Frame = +3 Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200 ++ KV F+TG +G+G ++ L G IA+ DI EA + + + G K+ + Sbjct: 4 FQGKVAFVTGGGSGLGRALSEELARRGAV-IAVTDINAEAAEHVAAAITES-GGKSCSMK 61 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN----DSIGI--YKKAIEVNVTALITS 362 DV+ E +++VV G +D + NNA ++ +G+ + + I+VN+ ++ Sbjct: 62 LDVSQPEDVAASIDSVVGRYGRLDYMFNNAGIIILGEVRDMGLEHWHRLIDVNLLGVLYG 121 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 T A M + G ++N++SV L Y ATK AV+ S + RPE SK Sbjct: 122 TTAAYSHMVRQGYGH---IVNIASVGGLVPLPTYAAYAATKHAVVGLSTSM-RPE-ASKL 176 Query: 543 GVRVLTVCFGATDTAL 590 GVR+ VC G +T L Sbjct: 177 GVRITVVCPGTMNTGL 192 >UniRef50_A1IFS9 Cluster: Short chain dehydrogenase family protein; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Short chain dehydrogenase family protein - Candidatus Desulfococcus oleovorans Hxd3 Length = 273 Score = 79.0 bits (186), Expect = 1e-13 Identities = 60/194 (30%), Positives = 96/194 (49%), Gaps = 6/194 (3%) Frame = +3 Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206 DKV +TG A+G+G +V +L G + I DI E+ + + + + G T + D Sbjct: 6 DKVFIVTGGASGMGRAVCELLGTRGA-ILIIADIDGESAEKVAAGITAAGGRATGVF-LD 63 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 368 T +E +++ E G +D + NNA ++ + S + + ++VN ++T TL Sbjct: 64 TTADETVRRLVDETAAEYGRLDYMFNNAGILIAGEVRDMSDDHWARILDVNFRGVLTGTL 123 Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 A IM + G +IN +S A L V+ Y TK AV+ S + RPE +K GV Sbjct: 124 AAYRIMVEQGFGH---IINTASTAGLVPIPVITAYATTKHAVVGLSISL-RPE-AAKAGV 178 Query: 549 RVLTVCFGATDTAL 590 RV VC G T++ Sbjct: 179 RVSVVCPGYVSTSI 192 >UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=4; Sphingomonas|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Pseudomonas paucimobilis (Sphingomonas paucimobilis) Length = 250 Score = 79.0 bits (186), Expect = 1e-13 Identities = 63/200 (31%), Positives = 97/200 (48%), Gaps = 6/200 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 M++ KV ITG A+G+G + + +EG K + I D+ EE K + E+ + G Sbjct: 1 MANRLAGKVALITGGASGLGAAQAKRFAEEGAK-VVIGDLNEEMAKGVVAEIRAA-GGDA 58 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTA 350 F R DVTD + + A V GG+ + N A +++ +SI + K + VN TA Sbjct: 59 LFIRLDVTDAASWNNAIAAAVDGFGGLTTLSNTAGIIHPGGFEEESIEGWNKMVAVNQTA 118 Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530 + AI + K SG G++IN+SS+ + + Y ATK+AV S Sbjct: 119 IFLGIKAAIPELVK-SG--NGSIINISSLIGMFPTAGNASYCATKAAVRIMSKAAAL--E 173 Query: 531 FSKTGVRVLTVCFGATDTAL 590 F GVRV T+ G +T + Sbjct: 174 FVDRGVRVNTIVPGGMNTPI 193 >UniRef50_P19871 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=4; Burkholderiales|Rep: 3-beta-hydroxysteroid dehydrogenase - Comamonas testosteroni (Pseudomonas testosteroni) Length = 254 Score = 79.0 bits (186), Expect = 1e-13 Identities = 51/168 (30%), Positives = 92/168 (54%), Gaps = 6/168 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 M++ + KV +TG A+G+G VV++LL EG K +A DI E AG+ L EL G ++ Sbjct: 1 MTNRLQGKVALVTGGASGVGLEVVKLLLGEGAK-VAFSDINEAAGQQLAAEL----GERS 55 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 350 F R DV+ E + ++ AV + G ++V++NNA ++ + + + +++N + Sbjct: 56 MFVRHDVSSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTES 115 Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 494 + + I M + GG++IN++SV++ Y A+K+AV Sbjct: 116 VFIGCQQGIAAMKE----TGGSIINMASVSSWLPIEQYAGYSASKAAV 159 >UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular organisms|Rep: Glucose 1-dehydrogenase - Oceanobacillus iheyensis Length = 256 Score = 78.6 bits (185), Expect = 1e-13 Identities = 59/197 (29%), Positives = 94/197 (47%), Gaps = 7/197 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 +DKV +TGAA G+G++ IL E + I D EE G+ + VE + G + F + Sbjct: 7 EDKVAIVTGAAMGMGKATA-ILFAESKAKVVIADFNEEKGQEV-VEEVKQAGGQAAFIKV 64 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITS 362 D++D ++ V + G +D+ +NNAAL D + K I V++T T+ Sbjct: 65 DISDSAQVKQMVQFAVDQFGKLDIAVNNAALTPDDKPASEFDEDYWDKLISVDLTG--TA 122 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 E+ G GG+++N+SSV+ Y A K V+ + + E+ Sbjct: 123 LCMKYELQQLLEQGNGGSIVNISSVSGFRPQPNNIAYVAAKHGVVGMTK-VAALEN-GPQ 180 Query: 543 GVRVLTVCFGATDTALL 593 +RV TV GA DT +L Sbjct: 181 NIRVNTVAPGAIDTPML 197 >UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SDR) family protein; n=1; Thermobifida fusca YX|Rep: Short-chain dehydrogenase/reductase (SDR) family protein - Thermobifida fusca (strain YX) Length = 282 Score = 78.6 bits (185), Expect = 1e-13 Identities = 57/194 (29%), Positives = 94/194 (48%), Gaps = 5/194 (2%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 M+ + +V ITG A+GIGE+ VR EG + I DI EAG+ L EL G++ Sbjct: 1 MTQRLRGRVAAITGGASGIGEATVRRFHTEGAS-VVIADIQAEAGRRLADEL----GDRA 55 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 368 F R+DV++E +++ V G +D+++NNA +M ++G + I L Sbjct: 56 VFVRTDVSEEADVAALVDTAVDRFGQLDIMVNNAGIMG-ALGPIDATRMSDADLTIAVNL 114 Query: 369 KAIEIMGKHSG-----GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533 + + KH+ + G +I+ SS A + IY A K ++ SN + Sbjct: 115 RGVICGMKHAARVMKPRRSGVIISTSSPAGVLGGIGPHIYSAVKVGIIGLSNSVA--AEL 172 Query: 534 SKTGVRVLTVCFGA 575 + G+RV T+ G+ Sbjct: 173 RQHGIRVNTIIPGS 186 >UniRef50_Q399N8 Cluster: Short-chain dehydrogenase/reductase SDR; n=27; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 595 Score = 78.6 bits (185), Expect = 1e-13 Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 7/201 (3%) Frame = +3 Query: 12 SHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAI-LDIAEEAGKSLQVELNSKYGNKT 188 S + KV +TGA +GIG EG +A +D+A +L + L G + Sbjct: 322 SGRFSGKVAVVTGAGSGIGRCAALAFAREGATIVACDIDLASAERTALLIGLT---GAQA 378 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTA 350 R DV + + V GG DVVINNA + ++ S +++ + VN+ Sbjct: 379 HAKRVDVGSADEMEALATWVGSALGGADVVINNAGIGMAGGILDTSTRHWERILHVNLWG 438 Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530 +I + + M G GG ++N +S AA S +P Y TK+AVL S C+ R E Sbjct: 439 VIHGSRLFAQQMAAR--GTGGHIVNTASAAAFGPSRDLPAYATTKAAVLMLSECM-RAE- 494 Query: 531 FSKTGVRVLTVCFGATDTALL 593 ++ G+ V VC G +T ++ Sbjct: 495 LAEQGIGVTAVCPGFAETGIM 515 >UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=3; Clostridium|Rep: 7-alpha-hydroxysteroid dehydrogenase - Eubacterium sp. (strain VPI 12708) Length = 266 Score = 78.6 bits (185), Expect = 1e-13 Identities = 53/211 (25%), Positives = 105/211 (49%), Gaps = 10/211 (4%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200 KDKV+ +T + GIG ++ + EG K ++ ++ E K+ E+N+ GN K+ Sbjct: 4 KDKVILVTASTRGIGLAIAQACAKEGAKVYMGARNL--ERAKARADEMNAAGGN-VKYVY 60 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINN---------AALMNDSIGIYKKAIEVNVTAL 353 +D T EE ++ ++ +++++G IDV++NN + N ++ K + +N+ ++ Sbjct: 61 NDATKEETYVTMIEEIIEQEGRIDVLVNNFGSSNPKKDLGIANTDPEVFIKTVNINLKSV 120 Query: 354 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533 ++ A++ M ++ GG++IN+SSV L Y +K+A+ + I H Sbjct: 121 FIASQTAVKYMAENG---GGSIINISSVGGLIPDISQIAYGTSKAAINYLTKLIA--VHE 175 Query: 534 SKTGVRVLTVCFGATDTALLTDEKLGTFDKY 626 ++ +R V G T T + D F + Sbjct: 176 ARHNIRCNAVLPGMTATDAVQDNLTDDFRNF 206 >UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Methylobacterium sp. 4-46 Length = 255 Score = 78.6 bits (185), Expect = 1e-13 Identities = 59/203 (29%), Positives = 96/203 (47%), Gaps = 6/203 (2%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV +TG A GIG + R +EG + + DI EAG + N + +F DV Sbjct: 7 KVALVTGGARGIGLATARRFAEEGAAAVILADIDAEAG-ARAAATNPVF----RFAPLDV 61 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL----MNDSIGI--YKKAIEVNVTALITSTLK 371 T + + + V +GG+DVV+N A + +S+ + +++ VNV Sbjct: 62 TQDAAWQDATDEAVAREGGLDVVVNCAGIAVVATIESVTLEQWRRVQAVNVDGTFLGCRH 121 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 A+ +M K G+GG +IN+SSV+ + H + Y A+K AV + + G+R Sbjct: 122 AVRVM-KPPAGRGGAIINLSSVSGIIGGHNLAAYNASKGAVRLLTKSVALHCARQGYGIR 180 Query: 552 VLTVCFGATDTALLTDEKLGTFD 620 ++ G T+T +L D G D Sbjct: 181 CNSIHPGFTETDMLHDLAAGGRD 203 >UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammaproteobacteria|Rep: Short chain dehydrogenase - marine gamma proteobacterium HTCC2143 Length = 259 Score = 78.6 bits (185), Expect = 1e-13 Identities = 54/210 (25%), Positives = 95/210 (45%), Gaps = 5/210 (2%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 MS + +V +TG A GIG + EG+ ++ + D+ ++ G+ + + GN Sbjct: 1 MSTTFSGQVALVTGGAAGIGRTTAAAFAREGL-NVVVADMDKDGGEETVAAIKAAGGNAI 59 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 368 F DVT E ++ G +D NNA + + G K E +++ + Sbjct: 60 -FVPCDVTKESDVQWLIETTCSTYGSVDYAFNNAGIDIEK-GELSKGTEDEFDSIMAVNV 117 Query: 369 KAIEIMGKHSGGK-----GGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533 K + + KH + GGT++N SS+ L + M IY A+K AV+ + Sbjct: 118 KGVWLCMKHQITQMITQGGGTIVNTSSIGGLGAAPNMSIYCASKHAVIGLTKSAAVEN-- 175 Query: 534 SKTGVRVLTVCFGATDTALLTDEKLGTFDK 623 ++ G+R+ VC G DT + ++ FD+ Sbjct: 176 ARNGIRINAVCPGVIDTNMFNRSRM--FDR 203 >UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20; Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase - Oceanobacillus iheyensis Length = 255 Score = 78.2 bits (184), Expect = 2e-13 Identities = 67/202 (33%), Positives = 100/202 (49%), Gaps = 13/202 (6%) Frame = +3 Query: 42 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTDEE 221 +TG A+G+GE+ VR L ++G K +AI D+ +E G+ L EL G+ +++ DVTDE Sbjct: 10 VTGGASGLGEATVRRLHNQGGK-VAIFDLNKENGERLATEL----GDNVDYFQVDVTDET 64 Query: 222 HFLGILNAVVQEQGGIDVVINNA--ALMNDSIG--------IYKKAIEVNVTALITSTLK 371 L+ V+++ GI V+N A A+ +IG + IE+N+ Sbjct: 65 SVQKALDNVMEQSDGIHAVVNCAGIAIAEKTIGKKGVHSLQHFSNVIEINLIGTFNVIRL 124 Query: 372 AIEIMGKHS---GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 A E M +S G+ G +IN +SVAA Y A+K V + I R S Sbjct: 125 AAEKMALNSPNDEGERGVIINTASVAAFEGQIGQAAYSASKGGVAGMTLPIAR--DLSTL 182 Query: 543 GVRVLTVCFGATDTALLTDEKL 608 G+RV+T+ G T L EKL Sbjct: 183 GIRVMTIAPGLFLTPLF--EKL 202 >UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 252 Score = 78.2 bits (184), Expect = 2e-13 Identities = 60/191 (31%), Positives = 90/191 (47%), Gaps = 6/191 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV ITG ATGIG + + EG + I DI EE G S VE G F R DV Sbjct: 7 KVALITGGATGIGRATALLFAREGA-CVLIGDINEE-GASETVEAVRAAGGDAAFRRCDV 64 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 371 + EE ++ A +E G +DVV NA L+ S ++ + +N+TA T Sbjct: 65 SGEEEIAALVAAAGEEYGRLDVVFGNAGLLRTRPLEDLSTKEFELHLRINLTANFLLTKY 124 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 A +M +H +GG++I ++S L + Y A+K ++ + + + + +R Sbjct: 125 AAPVMRRH---EGGSIIFMASAGGLRGTRGSVAYNASKGGLVNMTRSLA--DELAPHNIR 179 Query: 552 VLTVCFGATDT 584 V VC G DT Sbjct: 180 VNCVCPGWVDT 190 >UniRef50_A1UMZ0 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=5; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR precursor - Mycobacterium sp. (strain KMS) Length = 261 Score = 78.2 bits (184), Expect = 2e-13 Identities = 59/200 (29%), Positives = 93/200 (46%), Gaps = 8/200 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 +V +TG A+GIG + L EG++ + +LDI A +++ + G R DV Sbjct: 6 RVALVTGGASGIGRATAGRLAAEGMR-VCVLDIDGPATEAVAESIGG-IG-----LRCDV 58 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMND---SIGI-----YKKAIEVNVTALITST 365 TD E + V E GG+DV NA + D IG Y+K++ VNV ++ Sbjct: 59 TDPEQVDSAFDTCVAELGGVDVAFLNAGITIDWSGDIGALDLAQYRKSVGVNVDGVVFGV 118 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 A+ M G ++ +S+A L H P+Y K V+ F I + + G Sbjct: 119 RAAVRTMRTLDPGVDRAILATASLAGLMPWHPDPVYSLGKHGVVGFMRSIA--PNLAAEG 176 Query: 546 VRVLTVCFGATDTALLTDEK 605 + V T+C G T+T +L D + Sbjct: 177 IAVHTICPGITETGVLGDRR 196 >UniRef50_Q22CU9 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Tetrahymena thermophila SB210 Length = 843 Score = 78.2 bits (184), Expect = 2e-13 Identities = 58/192 (30%), Positives = 94/192 (48%), Gaps = 6/192 (3%) Frame = +3 Query: 36 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 215 V +TGAA G G+ + + +I I DI E+ + E+ K G K FY+ DV+D Sbjct: 577 VLLTGAAMGAGKFLAMNFAKKNNCNIIIYDIREDLMGQVIEEIQ-KAGAKGYFYKCDVSD 635 Query: 216 EEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLKAI 377 E+ + + +Q+ ID++INN + N S +KA VN A ++ K + Sbjct: 636 EQELQRTVESTLQKFQKIDILINNVGIANLKLFTDVSFDEVQKAFSVNFLAPVSIIKKIL 695 Query: 378 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557 +M + + G ++NVSSVA+L S M Y A+K+A+ F N + K + Sbjct: 696 PVMIERNQGH---IVNVSSVASLMPSAKMTDYCASKAALSGFHNALRLELKQQKKNINTT 752 Query: 558 TVCFGATDTALL 593 +C A +T +L Sbjct: 753 LICPYAVNTGVL 764 >UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=1; Ralstonia eutropha JMP134|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 258 Score = 77.8 bits (183), Expect = 2e-13 Identities = 60/202 (29%), Positives = 100/202 (49%), Gaps = 8/202 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K+ +TG A+G+G + R L EG + + DI AG + + EL G F R DV Sbjct: 6 KIALVTGGASGMGLAFTRRLAQEGAR-VYFTDINGAAGHATESELQGA-GLAVVFLRHDV 63 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGI-----YKKAIEVNVTALITSTLK 371 T E +L +L + G +DV++NNA + ++ +I + + + VN+ ++ Sbjct: 64 TQENDWLRVLEHIGAVDGRLDVLVNNAGIAISHNIETCTTEDFDRTLNVNLKSVFLGCKH 123 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG-- 545 + +M + KGG++INVSS+ A+ V Y A+K+ V S + H ++ G Sbjct: 124 GLALMKQ----KGGSIINVSSITAICGEPVALAYSASKAGVRFLSKSVAL--HCAEKGYA 177 Query: 546 VRVLTVCFGATDTALLTDEKLG 611 +RV ++ G DT LL G Sbjct: 178 IRVNSLHPGYIDTPLLAGSNAG 199 >UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=3; Clostridium perfringens|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A) Length = 272 Score = 77.8 bits (183), Expect = 2e-13 Identities = 57/197 (28%), Positives = 98/197 (49%), Gaps = 7/197 (3%) Frame = +3 Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200 + DKV+ ITGAA GIG++V EG K + + D EE K E+ N +F Sbjct: 9 FSDKVMIITGAAGGIGKAVALRAAKEGAK-LVLADRKEEMSKETLKEIREITSN-VEFLI 66 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALIT 359 D+ + E+ +++ +++ GG+D++INNA + S +++ ++ N+ Sbjct: 67 CDLREGENCKKVIDTAIKKFGGLDILINNAGITGTPAPVHEMSEEMFRNVLDCNIMIAFH 126 Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539 + I+ M K + KGG ++NVSSVA LT Y +K + + + +++ Sbjct: 127 CSHYGIQEMIKQN--KGGAIVNVSSVAGLTGFPGHSAYVTSKHGLNGLTRNMAL--DYAR 182 Query: 540 TGVRVLTVCFGATDTAL 590 G+RV V G TDT + Sbjct: 183 YGIRVNAVNPGTTDTPM 199 >UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Pelobacter|Rep: Short-chain dehydrogenase/reductase SDR - Pelobacter propionicus (strain DSM 2379) Length = 283 Score = 77.8 bits (183), Expect = 2e-13 Identities = 57/206 (27%), Positives = 101/206 (49%), Gaps = 10/206 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV ITGA GIG ++ L +G + + D+ + + E+ ++ G K R+DV Sbjct: 24 KVAIITGAGRGIGRAIALRLGADGAAMV-VSDVNGDNATKVAEEIKAR-GGKAMALRTDV 81 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVT-ALITSTL 368 T E +++ V++ G +D+++ NA + N + I + + + VN A + T+ Sbjct: 82 TSEADVKDLIDTAVRQHGRLDIMVANAGIANIKMSIEMTGAEWDQIMAVNTKGAFLCDTM 141 Query: 369 KAIEIMGK-HSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539 A +++ + HS G GG +IN +S+AA + ++ Y A+K AV F+ + + K Sbjct: 142 AARQMIKQGHSETPGSGGKIINCASIAAHSGFSILAAYSASKFAVRGFTQALAKELGPYK 201 Query: 540 TGVRVLTVCFGATDTALLTDEKLGTF 617 V TD L DEK+G + Sbjct: 202 INVNAYCPGIVGTDMWTLIDEKMGPY 227 >UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Lin2278 protein - Listeria innocua Length = 253 Score = 77.4 bits (182), Expect = 3e-13 Identities = 50/197 (25%), Positives = 99/197 (50%), Gaps = 8/197 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV +TGAA+G+G+ + + EG K + + D+ EA + + + G ++V Sbjct: 7 KVAVVTGAASGMGQQIAVLFAKEGAK-VVVADLNLEAAQKTVALIEDEQGTALAVV-ANV 64 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITSTL 368 T ++ ++N + G +D+++NNA +M++ + ++ K +N T ++ +T Sbjct: 65 TKQDDIESMINKATETYGTLDILVNNAGIMDNFVPAGELTDELWDKVFAINTTGVMRATR 124 Query: 369 KAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 KA+ I + KG G ++N++S L S Y A+K AV+ F+ +G ++ Sbjct: 125 KALHIFEE----KGQGVIVNIASAGGLFGSRAGAAYTASKHAVVGFTKNVG--FQYANKN 178 Query: 546 VRVLTVCFGATDTALLT 596 +R + GA +T + T Sbjct: 179 IRCNAIAPGAVNTNIGT 195 >UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus iheyensis|Rep: Oxidoreductase - Oceanobacillus iheyensis Length = 257 Score = 77.4 bits (182), Expect = 3e-13 Identities = 59/199 (29%), Positives = 105/199 (52%), Gaps = 7/199 (3%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197 +++DKV+ +TGAA GIG+ VVR + + K + ++D+ E+A KS+Q EL N + Sbjct: 3 KFQDKVIIVTGAAGGIGKEVVRKVANAQAK-VVLVDLNEDAIKSVQAELGLTEEN-SFVV 60 Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALI 356 ++DV++EE+ ++ + + G ID +NNA + + I + +NV ++ Sbjct: 61 KADVSNEENVKNYVDQTIAKFGRIDGFVNNAGVEGPAKSIEEITEKEFDFVYGINVKGVL 120 Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536 + +M K G+++N +SVA L S M +Y ++K AV+ N + E + Sbjct: 121 FGLKYVLPVM---KAQKSGSIVNTASVAGLIGSPSMALYNSSKHAVMGL-NKVAALES-A 175 Query: 537 KTGVRVLTVCFGATDTALL 593 VRV TV G +T ++ Sbjct: 176 AFNVRVNTVNPGVINTQMM 194 >UniRef50_Q82FK0 Cluster: Putative dehydrogenase; n=2; Streptomyces|Rep: Putative dehydrogenase - Streptomyces avermitilis Length = 584 Score = 77.4 bits (182), Expect = 3e-13 Identities = 55/194 (28%), Positives = 97/194 (50%), Gaps = 9/194 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS-D 206 ++V +TGA +GIG + + G + +A+ AE A ++ E++ G + + D Sbjct: 317 QLVLVTGAGSGIGRATAYAFAEAGARVVAVDRNAEGAART--AEMSRLIGAPDAWAETVD 374 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTL 368 V+DE+ + V E G +DV++NNA + + + ++K ++VN+ +I Sbjct: 375 VSDEQAMEKLAEKVATEYGVVDVLVNNAGIGLSGSFFDTTAEDWRKVLDVNLWGVI---- 430 Query: 369 KAIEIMGKHSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 + GK G+GG ++N +S AA S +P Y +K+AVL S C+ R E + Sbjct: 431 HGCRLFGKQMAERGQGGHIVNTASAAAYQPSKALPAYSTSKAAVLMLSECL-RAE-LAGQ 488 Query: 543 GVRVLTVCFGATDT 584 G+ V +C G T Sbjct: 489 GIGVSAICPGFVHT 502 >UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2; Bacteria|Rep: Short-chain dehydrogenase - Symbiobacterium thermophilum Length = 254 Score = 77.4 bits (182), Expect = 3e-13 Identities = 60/194 (30%), Positives = 90/194 (46%), Gaps = 6/194 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV ITGAA G+G + + EG + + I D+ EE G++ Q G F R+DV Sbjct: 7 KVAIITGAAMGMGAATAELFAREGAR-VVIADLNEELGRA-QARKIQDAGGAAAFVRADV 64 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 389 + ++ V G +DV +NNAA D+ + E A+I LK + + Sbjct: 65 SRAGDVEAMVQFAVDTFGRLDVAVNNAAHSPDTRPL-ADLDEAVWDAVIGVDLKGVALCL 123 Query: 390 KHS------GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 K+ G GG++IN+SSV+ + P Y A K V+ + +S G+R Sbjct: 124 KYELRQMLKQGGGGSIINISSVSGIRPQPGTPAYVAAKHGVIGLTKQAAM--DYSPHGIR 181 Query: 552 VLTVCFGATDTALL 593 V V GA DT +L Sbjct: 182 VNAVAPGAVDTPML 195 >UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain KSM-K16) Length = 247 Score = 77.4 bits (182), Expect = 3e-13 Identities = 64/207 (30%), Positives = 102/207 (49%), Gaps = 7/207 (3%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197 E +KVV ITG A+GIG + V L +G K + I D +E G++ EL G + F Sbjct: 3 ELTNKVVIITGGASGIGRAAVDAFLAKGAK-VVIADFNKETGEAAVKELTDA-GKQVLFV 60 Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDS----IGIYKKAIEVNVTALIT 359 ++DV++E ++ V+ +D++INNA M+ S Y+K ++V + Sbjct: 61 QTDVSNEPSVQNMVAETVKAYERVDILINNAGFGTMSPSHERTYEDYEKIVKVCQDGVFL 120 Query: 360 STLKAIEIMGKHSGGKGGTVINVSSV-AALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536 + AI+ M K GG +IN SS+ ++ Q +P Y A K AV + + ++ Sbjct: 121 GSKHAIKEMIKTG---GGCIINTSSILGSVAQPEALP-YNAAKGAVNTMTKSLA--VEYA 174 Query: 537 KTGVRVLTVCFGATDTALLTDEKLGTF 617 +RV V G +TA + E LG F Sbjct: 175 DKQIRVNAVAPGFVETAAVNKEALGDF 201 >UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 253 Score = 77.4 bits (182), Expect = 3e-13 Identities = 58/197 (29%), Positives = 97/197 (49%), Gaps = 7/197 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 KDKV +TG A+GIGE+ VR+ +G + I D G+ L EL S+ + Sbjct: 9 KDKVAIVTGGASGIGEATVRLFASQGAS-VVIAD-RSALGEKLAREL-SESSLAAHYSEV 65 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 362 DV+ E+ +++ V G +D+++ NA + + S + +++ I+VN+T + S Sbjct: 66 DVSREDDTRRLIDDTVSRFGRLDIMVANAGIAHPSAPVEDVSVEQWQQMIDVNLTGVFLS 125 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 AI M K G GG ++N++S+ Y A K V+ + +G H ++ Sbjct: 126 NKLAIVQMKKQ--GTGGAIVNMASILGHVGMPGAASYNAAKGGVVNLTRSLG-VSH-AQD 181 Query: 543 GVRVLTVCFGATDTALL 593 G+RV VC G T L+ Sbjct: 182 GIRVNAVCPGFVATPLI 198 >UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Mesorhizobium sp. BNC1|Rep: Short-chain dehydrogenase/reductase SDR - Mesorhizobium sp. (strain BNC1) Length = 257 Score = 77.4 bits (182), Expect = 3e-13 Identities = 56/192 (29%), Positives = 94/192 (48%), Gaps = 5/192 (2%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS-D 206 KV +TGAA G+GE++ L +G + +A+LD+ +E G + + GN +YR+ D Sbjct: 7 KVALVTGAARGLGEAIAVELAAQGAR-VALLDVLDELGAEVAENIKKSSGN--AYYRNCD 63 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEV--NVTALITSTLKAI- 377 + D E ++ V G +DV++NNAA+ I + + E N+ + S++ Sbjct: 64 IRDTEEVRSAVDEVYSTYGKLDVLVNNAAVSTAPTSIPELSEETWNNIFNVNVSSIYRFC 123 Query: 378 -EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554 ++ + GG VIN+SSV Y ATK A++ S + + + +RV Sbjct: 124 RFVLPRMQEAGGGAVINMSSVHQSHSLTGWTAYAATKGAIISMSRQLA--AEWGRFNIRV 181 Query: 555 LTVCFGATDTAL 590 TV GA D + Sbjct: 182 NTVSPGAIDATM 193 >UniRef50_A0HI81 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Comamonas testosteroni KF-1 Length = 259 Score = 77.4 bits (182), Expect = 3e-13 Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 + ITGA GIG + + EG + + AE ++ + L + G + +DV Sbjct: 9 RTALITGAGAGIGAAASHLFCKEGAAVLMVDANAEALERTREAILQAVPGARLACVMADV 68 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE------VNVTALITSTLK 371 +DE + VQ+ GG+D ++NNAA+ N S A E VN+ + Sbjct: 69 SDESAAAAAVGQCVQQWGGLDTLVNNAAMRNYSAAADATAAEWQAMVGVNLVGMSNYCRA 128 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 A+ + + SG G+++NVSS A+T M +Y ATK+A L ++ + E + GVR Sbjct: 129 ALPAL-RQSG--TGSIVNVSSCYAVTGRKGMALYDATKAAQLAYTRSLAFEE--AAHGVR 183 Query: 552 VLTVCFGATDT 584 VC G+T T Sbjct: 184 ANAVCPGSTLT 194 >UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019; n=11; cellular organisms|Rep: Uncharacterized oxidoreductase TM_0019 - Thermotoga maritima Length = 256 Score = 77.4 bits (182), Expect = 3e-13 Identities = 53/192 (27%), Positives = 96/192 (50%), Gaps = 6/192 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV +TG GIG ++ ++ + G+K + I +I EEAG + L + G F ++DV Sbjct: 5 KVAVVTGGGQGIGAAIAQLFAENGMK-VVIAEIDEEAGVEREEMLRER-GLDVTFVKTDV 62 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 371 DE ++ V+ GG+DV++NNAA+M+ + +++ I VN+T + Sbjct: 63 ADENSVKNMVRKTVEIYGGVDVLVNNAAVMSVKSIFERPLEEWERVIRVNLTGPYICSRY 122 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 E M K GG +IN++S A Y A+K ++ ++ + S+ +R Sbjct: 123 CAEEMIKRG---GGVIINIASTRAFQSEPDTEPYSASKGGLVALTHSLA--VSLSRYHIR 177 Query: 552 VLTVCFGATDTA 587 V+++ G +T+ Sbjct: 178 VVSISPGWIETS 189 >UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=17; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Chromobacterium violaceum Length = 246 Score = 77.0 bits (181), Expect = 4e-13 Identities = 56/196 (28%), Positives = 95/196 (48%), Gaps = 6/196 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 K KV ITG+A+GIG++ + EG +A+ D+ +A K++ EL + G + Y+ Sbjct: 4 KGKVSIITGSASGIGKATAEKFVKEGAI-VAVCDLNPDAVKTVVDELKA-LGGEAYGYKV 61 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 365 DVTD+ ++ + G IDV++NNA ++ D+ I + K I++N+ + Sbjct: 62 DVTDKGQIAEMVADLKNRCGRIDVLVNNAGIVQDAQLIKMSEDQFDKVIDINLKGVYNCA 121 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 ++ M + GG ++N SSV + + Y A K V+ F + K G Sbjct: 122 RAVVDTMVEQG---GGVILNASSVVGVYGNFGQTNYAAAKFGVIGFVKTWAK--ELGKKG 176 Query: 546 VRVLTVCFGATDTALL 593 +R VC G T +L Sbjct: 177 IRANAVCPGFVATPIL 192 >UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 250 Score = 77.0 bits (181), Expect = 4e-13 Identities = 48/169 (28%), Positives = 89/169 (52%), Gaps = 7/169 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV +TGAA GIG ++ + EG K + I DI + G+ + EL G + F+ +DV Sbjct: 10 KVAIVTGAANGIGVAIATRFVTEGAK-VVIADI-DAGGQGVAAEL----GERATFFSTDV 63 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNVTALITSTL 368 +D +++ ++ GG+ V+ NNA + ++D + +++ + V++ ++ + Sbjct: 64 SDPVQTQALVDFTIRHFGGLHVLCNNAGVSGGLRRFLDDDLRDFERVVAVDLYGVMACSR 123 Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 515 A M H GG ++N++S A +T M Y A K+ V+QF+ C+ Sbjct: 124 SAARHMVDHGGG---AIVNIASGAGITPGIGMLPYRAAKAGVVQFTRCL 169 >UniRef50_Q15Q07 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Gammaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 270 Score = 77.0 bits (181), Expect = 4e-13 Identities = 60/198 (30%), Positives = 97/198 (48%), Gaps = 9/198 (4%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 K KV+ ITG ATGIG +V + + + + +D+ EEA +L +L+++ G F Sbjct: 26 KGKVILITGGATGIGAVMVEAFMRQQAR-VLFVDVQEEAAHALCSKLHAELGAAPIFKNL 84 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITS 362 D T + ++++ G +DV+INN A L D G ++ + VN+ + + Sbjct: 85 DTTHIDELQAFISSIGHSHGRLDVLINNVANDTRHSPLDIDQQG-WRDCMAVNLDSTFFA 143 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 AI +M + G +IN+SS+ L MP Y A KSA+ S + + + Sbjct: 144 CQSAIRLM---RDKRTGNIINMSSINVLIGPKQMPGYVAAKSALNGLSKSLA--NQYGEY 198 Query: 543 GVRVLTVCFG--ATDTAL 590 G+RV T+ G ATD L Sbjct: 199 GIRVNTILPGWVATDRQL 216 >UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=4; Shewanella|Rep: Short-chain dehydrogenase/reductase SDR precursor - Shewanella sp. (strain ANA-3) Length = 292 Score = 77.0 bits (181), Expect = 4e-13 Identities = 53/200 (26%), Positives = 97/200 (48%), Gaps = 7/200 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEA-GKSLQVELNSKYGNKTKFYR 200 K KV ITG+ +GIG + +L ++G H+ + + EA G+ L E +Y T F Sbjct: 35 KGKVGLITGSTSGIGLATAHVLAEQGC-HLILHGLMPEAEGRRLAAEFAEQYHIHTYFSN 93 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITS 362 +D+ D E ++A V+ G ID+++NNA + + I + I +N+++ + Sbjct: 94 ADLRDPESIHAFMDAGVKALGSIDILVNNAGIQHTENVAHFPIDKWNDIIAINLSSAFHT 153 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 +A+ M + + G +IN++SV L S Y A K ++ + + ++ Sbjct: 154 IQQAVPAMAEK---RWGRIINIASVHGLVASVNKAAYCAAKHGIVGLTKVVA--IECAEQ 208 Query: 543 GVRVLTVCFGATDTALLTDE 602 G+ V +C G DT L+ + Sbjct: 209 GITVNAICPGWVDTPLINKQ 228 >UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=2; Euryarchaeota|Rep: Predicted short chain dehydrogenase - Methanosphaera stadtmanae (strain DSM 3091) Length = 253 Score = 77.0 bits (181), Expect = 4e-13 Identities = 58/206 (28%), Positives = 95/206 (46%), Gaps = 7/206 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 K KV ITGA GIG+S+ + +EG I I E + + E+NS G+ + Sbjct: 4 KGKVAIITGATAGIGKSIAYLFAEEGASTILIARRKERL-EQITNEINSNGGDASACI-G 61 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 362 DVT +E ++ + + G ID+++NNA +M+D + + + K I+VN+T + Sbjct: 62 DVTKQEDIDNVVKLALDKYGKIDIIVNNAGIMDDFVSVKHIDDDLWDKTIDVNLTGPMRL 121 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 I M K++ GG +I +SSV L Y A+K V+ + + K Sbjct: 122 IRAVIPEMIKNN---GGNIITISSVGGLIGKISGAAYTASKHGVIGLAKHTAWV--YGKH 176 Query: 543 GVRVLTVCFGATDTALLTDEKLGTFD 620 +R + G +T + T G D Sbjct: 177 NIRSNVIAPGTVNTEIATTINPGRMD 202 >UniRef50_Q71R50 Cluster: Dehydrogenase/reductase SDR family member 11 precursor; n=7; Eukaryota|Rep: Dehydrogenase/reductase SDR family member 11 precursor - Gallus gallus (Chicken) Length = 255 Score = 77.0 bits (181), Expect = 4e-13 Identities = 54/196 (27%), Positives = 95/196 (48%), Gaps = 8/196 (4%) Frame = +3 Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200 W +V +TGA+ GIG +V R L+ G+K + ++ K ++ Y Y+ Sbjct: 4 WTGRVALVTGASVGIGAAVARALVQHGMKVVGCARSVDKIEKLAAECQSAGYPGTLIPYK 63 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITS 362 D+++EE L + +A+ G+DV INNA L++ ++ I+VNV A+ Sbjct: 64 CDLSNEEEILSMFSAIKTLHQGVDVCINNAGLARPEPLLSGKTEGWRTMIDVNVMAVSIC 123 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSV--AALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536 T +A + M K G +IN++S+ ++ V+ Y ATK AV + + + + Sbjct: 124 TREAYQSM-KERNIDDGHIININSMNGHSVVPQSVVHFYSATKYAVTALTEGLRQELREA 182 Query: 537 KTGVRVLTVCFGATDT 584 KT +R + G +T Sbjct: 183 KTHIRATCISPGLVET 198 >UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n=2; Proteobacteria|Rep: 2O-beta-hydroxysteroid dehydrogenase - Pseudoalteromonas haloplanktis (strain TAC 125) Length = 262 Score = 76.6 bits (180), Expect = 5e-13 Identities = 57/210 (27%), Positives = 102/210 (48%), Gaps = 6/210 (2%) Frame = +3 Query: 3 LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN 182 +K + +KV +TGAA GIG ++ + L+D G IA + EE + Q + G+ Sbjct: 1 MKNATHLTNKVALVTGAARGIGRAICQALVDSGATVIATDILTEELNQMAQ-----ELGD 55 Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNV 344 K DVTDE + I++A +++ ID+++NNA ++ ++K I++N+ Sbjct: 56 KVTPMTHDVTDELQWQSIVSATLEKHQKIDILVNNAGILLFATLETTEPQQFRKLIDINI 115 Query: 345 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 524 T I M K +G G ++N+SS +++ ++ Y A+K AV + Sbjct: 116 TGTFLGLHSVIPCM-KKAG--SGAIVNISSASSILPNNGTGAYAASKYAVRGLTRTAAL- 171 Query: 525 EHFSKTGVRVLTVCFGATDTALLTDEKLGT 614 G+RV +V GA +T + + L + Sbjct: 172 -ELGPFGIRVNSVHPGAVNTPMTNPQGLSS 200 >UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase; n=1; Burkholderia xenovorans LB400|Rep: Putative short-chain type dehydrogenase - Burkholderia xenovorans (strain LB400) Length = 252 Score = 76.6 bits (180), Expect = 5e-13 Identities = 62/199 (31%), Positives = 92/199 (46%), Gaps = 6/199 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 M+ K + ITGA IG+ R + EG + + I DIAEEAG+++ EL G Sbjct: 1 MAGRLSGKRIIITGAIGNIGKEAARGFIAEGAR-VVIGDIAEEAGRAVAAEL----GAAA 55 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 368 F + DVT E ++ V+ GG+D + NA L G + N AL Sbjct: 56 HFVQVDVTSEASVANLIARGVEWLGGLDALAQNAGLQRS--GAIAGFEQANWDALFAVNA 113 Query: 369 KAIEIMGKHS------GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530 +A KH+ GK G++IN+SS+A + Y A+K AV+ F+ + Sbjct: 114 RAHFFGAKHAIPHLQRSGK-GSIINMSSLAGKRGGPGLVAYSASKGAVIAFTTALAL--E 170 Query: 531 FSKTGVRVLTVCFGATDTA 587 + +RV +C G DTA Sbjct: 171 LAPDNIRVNAICPGWVDTA 189 >UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8; Bacteria|Rep: Short-chain alcohol dehydrogenase - Burkholderia dolosa AUO158 Length = 284 Score = 76.6 bits (180), Expect = 5e-13 Identities = 58/195 (29%), Positives = 100/195 (51%), Gaps = 7/195 (3%) Frame = +3 Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206 +KVV ITGA++GIGE+ ++L +G +A+ + + + E+ +K G + ++ D Sbjct: 44 NKVVVITGASSGIGEATAKLLASKGAT-VALAARRLDKLQRVAAEIVAK-GGQVSVHQVD 101 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS-IGIYK-----KAIEVNVTALITSTL 368 VTD+E ++N VV + G +DV++NNA LM + + + K + I++N+ L+ Sbjct: 102 VTDQEQVNRLINDVVSQHGRLDVMVNNAGLMAIAPLSLRKTDEWDRMIDINIKGLLYGVA 161 Query: 369 KAIEIMGKHSGGKGGTVINVSSVAAL-TQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 A+ + K + G +N++SV L S +Y TK AV S + H Sbjct: 162 AALPVFEKQ---QSGHFVNIASVVGLKVFSPGGTVYSGTKFAVRAISEGL---RHEVGGN 215 Query: 546 VRVLTVCFGATDTAL 590 +R + GA DT L Sbjct: 216 IRTTVISPGAIDTEL 230 >UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR; n=19; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 246 Score = 76.6 bits (180), Expect = 5e-13 Identities = 56/193 (29%), Positives = 92/193 (47%), Gaps = 6/193 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K+ +TGA GIG+++ L EG + + D+ +A K L+ + +DV Sbjct: 7 KIAVVTGAGQGIGKAIATKLAAEGAT-VVVTDVDHQAAKETAAALD----HGAIGLHADV 61 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITSTLK 371 TD +++ VV G IDV++NNA A ++ + + I +N+ ++ ++ K Sbjct: 62 TDRTSVDAMVDEVVATFGRIDVLVNNAGWDKGEAFVDSEPETWDRIIGINLYGVLNTSKK 121 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 + IM G+V+N+ S A S +Y A K V+ FS R +++ V Sbjct: 122 VLPIMAAQG---SGSVVNIGSDAGRVGSSGEAVYSAAKGGVIAFSKATAR--EMARSQVN 176 Query: 552 VLTVCFGATDTAL 590 V VC G TDTAL Sbjct: 177 VNCVCPGPTDTAL 189 >UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Rep: Short chain dehydrogenase - Mycobacterium avium (strain 104) Length = 594 Score = 76.6 bits (180), Expect = 5e-13 Identities = 56/195 (28%), Positives = 92/195 (47%), Gaps = 6/195 (3%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197 E + ++ +TGA GIG + L +G + + I+D + A + G Y Sbjct: 322 EVRGRLALVTGAGAGIGRATAVELARQGARKVVIVD-RDRAAADQTADAVRAAGAGAAVY 380 Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 377 + DV+DE + V E G +D+++NNA + G + + N A++ ++ + Sbjct: 381 QVDVSDEAAMNDLAAQVRNEHGVVDILVNNAGI--GMAGRFLETSPANWDAIMGVNVRGV 438 Query: 378 EIMGKHSG------GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539 + G G+GGT+INV+S AA S M Y TK+AVL S + R + F+ Sbjct: 439 IWGSRAFGAQMVERGQGGTIINVASAAAYLPSKSMVAYGTTKAAVLALSESL-RAD-FAD 496 Query: 540 TGVRVLTVCFGATDT 584 G+ V VC G +T Sbjct: 497 EGITVTAVCPGFVNT 511 >UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Thermotoga|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Thermotoga maritima Length = 257 Score = 76.2 bits (179), Expect = 7e-13 Identities = 54/198 (27%), Positives = 94/198 (47%), Gaps = 8/198 (4%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 K KV +TG GIG+++ + L G + I+DI EE + E+ K G + FY Sbjct: 11 KRKVALVTGGGQGIGKAIAQALAAAGAA-VLIMDINEETARRTVEEIKEK-GGEADFYVG 68 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 365 DVT EE G + + G +D+ +NNA + N + +KK I+VN+ + S Sbjct: 69 DVTKEEDCFGAVKKALDRWGKLDIGVNNAGIGDWCEAENYPVEKWKKVIDVNLVGVFLSA 128 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAA--LTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539 M + GK +IN++S++ + + Y A+K+ V+ + + ++ Sbjct: 129 KAEFHAMKERKYGK---IINIASMSGHIVNKPQKQTAYNASKAGVIHLTRSLA--AEWAP 183 Query: 540 TGVRVLTVCFGATDTALL 593 G+RV ++ G T L+ Sbjct: 184 YGIRVNSISPGYIRTPLI 201 >UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus sp. B14905 Length = 254 Score = 76.2 bits (179), Expect = 7e-13 Identities = 54/195 (27%), Positives = 95/195 (48%), Gaps = 6/195 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 ++KV ITG TGIG+ + EG K I I DI E++G ++ + +G + F Sbjct: 7 ENKVAVITGGGTGIGKETALLFAKEGAK-IVITDINEQSGNETVSDIQA-FGGEALFVLH 64 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 365 DV++E+ + + + + +D++ NNA L + + + + +NVT + Sbjct: 65 DVSNEDDWKKVADEAIHTFNKVDILFNNAGIYIIKPLAEIELSDWNRLMSINVTGVFLGM 124 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 + +M K + G+VIN SS+A LT + +Y A+K AV + ++ G Sbjct: 125 KHIMPLMAKQN---KGSVINASSIAGLTGAAGHVLYGASKGAVRIMTK--DAAMEYAPYG 179 Query: 546 VRVLTVCFGATDTAL 590 VRV ++ G DT + Sbjct: 180 VRVNSIHPGYIDTGM 194 >UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Candidatus Methanoregula boonei 6A8|Rep: Short-chain dehydrogenase/reductase SDR - Methanoregula boonei (strain 6A8) Length = 253 Score = 76.2 bits (179), Expect = 7e-13 Identities = 55/214 (25%), Positives = 100/214 (46%), Gaps = 6/214 (2%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV+ +TGA+ GIG + + + I + +SL E+ + G+ R+DV Sbjct: 12 KVILVTGASRGIGRATAFLAAKNHAQVIVNYQKHADQAESLVSEITA-LGHSAMAIRADV 70 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITSTLK 371 T EE + + ++ G +D+++NNA +M ++ I Y+ ++VN T Sbjct: 71 TCEEEVKEMFRQIREQYGRLDILVNNAGIMKNNLLMMTKIQEYQDVMDVNCKGTFLCTQH 130 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 A +IM + K GT+IN++SV + + Y ++KS V+ F+ C + + Sbjct: 131 AAKIMVRQ---KAGTIINLASVVGVYGNRGQSAYASSKSFVIGFTKCAAK--ELGAFNIT 185 Query: 552 VLTVCFGATDTALLTDEKLGTFDKYLESSCLDQL 653 V V G DT L D + + L++ L ++ Sbjct: 186 VNAVAPGFIDTDLTADTRSQVKEDILKNIALGRI 219 >UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Short-chain dehydrogenase/reductase SDR - Candidatus Nitrosopumilus maritimus SCM1 Length = 253 Score = 76.2 bits (179), Expect = 7e-13 Identities = 51/173 (29%), Positives = 95/173 (54%), Gaps = 10/173 (5%) Frame = +3 Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206 DKV +TGA++ IG+ + + ++EG K I I E ++ + E+ ++ + T D Sbjct: 5 DKVAIVTGASSDIGKGIAKKFVEEGAKVILIARNLEGL-ENTRKEIGNE--DSTAAMTCD 61 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALITST 365 + DE L ++N ++ G ID+++NNA +ND I + +K I VN+ + T Sbjct: 62 LVDESQTLQVVNQIMDTYGKIDILVNNAGAINDPIHFHEMQNSEIQKLINVNLLGVFNMT 121 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVA---ALTQSHVMPIYFATKSAVLQFSNCI 515 KA ++ K + K G+++N+ S++ A+ + H + +Y ATK+A+ F+ I Sbjct: 122 -KA--VLTKMADVKSGSIVNIGSISSERAIPRVH-LAVYSATKAAIPMFTKSI 170 >UniRef50_Q97EW4 Cluster: Predicted short-chain dehydrogenase; n=6; Clostridium|Rep: Predicted short-chain dehydrogenase - Clostridium acetobutylicum Length = 262 Score = 75.8 bits (178), Expect = 9e-13 Identities = 52/188 (27%), Positives = 94/188 (50%), Gaps = 5/188 (2%) Frame = +3 Query: 36 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 215 V ITGA+TGIG + RI G + ++ +E K L +EL K + D++ Sbjct: 3 VLITGASTGIGYEITRIFARNG--YDVVITARDE--KRL-IELAKNINTKVTVIKKDLSR 57 Query: 216 EEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKH 395 + + N + + +D+++NNA M D+ G++ K+ + ++ +K++ I+ + Sbjct: 58 PDSANELFNEIKENNIEVDILVNNAG-MGDT-GLFHKSSVDKINEMLELNIKSLTILTRL 115 Query: 396 SGG-----KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560 + G ++NV+S + + +Y+ATK+ VL F+ IG E K V+V Sbjct: 116 VSAEMVKKRSGMILNVASTGSYMPGPFIAVYYATKAYVLSFTEAIG--EELKKFNVKVSA 173 Query: 561 VCFGATDT 584 +C GAT T Sbjct: 174 LCPGATAT 181 >UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=6; Desulfuromonadales|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Geobacter sulfurreducens Length = 246 Score = 75.8 bits (178), Expect = 9e-13 Identities = 58/214 (27%), Positives = 99/214 (46%), Gaps = 5/214 (2%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197 E+KD +V +TG GIG ++ +G A +EA ++L+ E G+ Sbjct: 2 EFKDSIVVVTGGTRGIGRAISLHFARQGALVTAAYRADDEAARALEAEAAGLPGS-IAVI 60 Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 377 R+DV E + +++A E G + V++NNA ++ D G E + A++ + L + Sbjct: 61 RADVGTAEGAMAVIDAASGESGTLHVLVNNAGIIRD--GYLAMMAEDDWDAVMRANLSPL 118 Query: 378 EI-----MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 + K + G +IN+SSV+A + Y ATK A + F+ + R Sbjct: 119 FHCCKWGVRKMLARRRGAIINLSSVSAFAGTAGQTNYAATKGAAVSFTKSLAR--EVGPL 176 Query: 543 GVRVLTVCFGATDTALLTDEKLGTFDKYLESSCL 644 G+RV V G +T ++ K D+ + SS L Sbjct: 177 GIRVNAVAPGLIETEMIAGMKREMVDRIVGSSIL 210 >UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Staphylococcus epidermidis|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 255 Score = 75.8 bits (178), Expect = 9e-13 Identities = 53/188 (28%), Positives = 100/188 (53%), Gaps = 7/188 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV + G ATGIG+++ L G +I I D+ G+ ++++ G KT + D+ Sbjct: 13 KVAMVIGGATGIGKAMAEALAQAGA-NIVIADLQSNIGQETATTISTQSGVKTTSLKLDI 71 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNA--ALMNDSIGI-YKKAI-EVNVTALITSTLKAI 377 T + I++ VV+E G ID+++NNA ++ +D+ I Y++ + E+N++ + Sbjct: 72 THSDEVNQIVDYVVREYGKIDILVNNASISIQDDTENISYEEWLKEINLS--LNGAFSVA 129 Query: 378 EIMGKHSGGKG-GTVINVSSVAAL--TQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 + +G+ KG G++INVSSV L ++ Y +K+ V + + R +S+ G+ Sbjct: 130 QTVGRQMIEKGSGSIINVSSVLGLIANKTQDQSSYETSKAGVTMLTKSLAR--EWSRYGI 187 Query: 549 RVLTVCFG 572 +V + G Sbjct: 188 KVNAIAPG 195 >UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reductase; n=3; Proteobacteria|Rep: 3-ketoacyl-acyl carrier protein reductase - Pseudoalteromonas haloplanktis (strain TAC 125) Length = 247 Score = 75.8 bits (178), Expect = 9e-13 Identities = 59/203 (29%), Positives = 98/203 (48%), Gaps = 6/203 (2%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 M H+ D+VV +TGA GIG+S+V G ++A +DI + + ELN+ Sbjct: 1 MKHQ--DQVVLVTGAGQGIGQSIVSYFATAGA-NVAAVDINADTLNASVNELNANVAGNI 57 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 350 +++ + + AVV++ G +D +IN A A ++ + K I VN+T Sbjct: 58 VAITANIAKSDSVRDAIAAVVEKFGRLDAIINVAGVGSIDAFVDTPDEHWDKVIAVNLTG 117 Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530 +A ++M G +INVSS AALT Y A+K+ V+ + + R Sbjct: 118 TFLCCREAAKVMQAQG---SGCIINVSSTAALT-GEGPSHYCASKAGVMGLTRSMAR--E 171 Query: 531 FSKTGVRVLTVCFGATDTALLTD 599 + G+RV T+ G T+T ++ D Sbjct: 172 LAPVGIRVNTIVPGPTNTPMMAD 194 >UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 262 Score = 75.8 bits (178), Expect = 9e-13 Identities = 48/164 (29%), Positives = 83/164 (50%), Gaps = 7/164 (4%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 + KV ITG A GIG R L G +AILD+ + ++L E+ ++ G + F+ Sbjct: 11 RGKVAAITGGARGIGAETARTLAAAGAS-VAILDVLSQPAEALVEEIRAQ-GGQAAFWSL 68 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITS 362 DVT E + +V G +DV++NNA + ++ +++ ++VNV + Sbjct: 69 DVTHEADVARVFGEIVAHFGRLDVLVNNAGIEGHNVPTHELTLAQWQRVLDVNVNGVFLC 128 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 494 T AI + GG+++N+SS+ + +P Y A+K+AV Sbjct: 129 TRAAIPHI---DAAGGGSIVNLSSMYGIVGGPDVPAYHASKAAV 169 >UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rhodopseudomonas palustris BisB5|Rep: Short-chain dehydrogenase/reductase SDR - Rhodopseudomonas palustris (strain BisB5) Length = 263 Score = 75.8 bits (178), Expect = 9e-13 Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 7/195 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 +VV +TG A+GIG + +G + + DI + G VE + G++ ++ R+DV Sbjct: 21 RVVLVTGGASGIGRAAALAWARQGCS-VLVADIDDRGGAET-VEAIERLGSRARYQRNDV 78 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 368 TDE ++ V G +DV NNA + S I ++ I VN+ + S Sbjct: 79 TDERECASLVEQAVLHFGRLDVAFNNAGITGPSAYIANYPGADWRHVINVNLLGIFNSMQ 138 Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 + + S G G ++N +SV L Y A K V+ + C + ++G+ Sbjct: 139 PQLRLF--ESQG-AGVIVNTASVIGLRGVAGGSAYAAAKHGVIGLTKCAAL--EYGRSGI 193 Query: 549 RVLTVCFGATDTALL 593 R+ VC G +T L+ Sbjct: 194 RINAVCPGYIETPLV 208 >UniRef50_O86553 Cluster: Putative dehydrogenase; n=1; Streptomyces coelicolor|Rep: Putative dehydrogenase - Streptomyces coelicolor Length = 276 Score = 75.8 bits (178), Expect = 9e-13 Identities = 54/197 (27%), Positives = 99/197 (50%), Gaps = 7/197 (3%) Frame = +3 Query: 15 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF 194 HE+ + +TGA+ G+GE+ R L G H+ ++ + +A +L E+ + + + Sbjct: 2 HEYTNTTALVTGASKGLGEAYARELASRGA-HLVLVARSADALHALADEIRATHSVRVDV 60 Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALI 356 +D++D +L+AV +D+++NNA + + + ++++VNVTAL+ Sbjct: 61 IAADLSDRRSPQRVLDAVDGLGLDVDLLVNNAGMGAVGPFLVRPLAPNLQSVDVNVTALV 120 Query: 357 TSTLKAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533 + ++G +G G ++N++S AA Y ATK+ VL F+ + E Sbjct: 121 ----GLVHLLGARMVERGRGGIVNIASTAAFQPMPYQASYAATKAFVLSFTEAVA--EEV 174 Query: 534 SKTGVRVLTVCFGATDT 584 TGVRV+ GAT T Sbjct: 175 RGTGVRVMAAHPGATAT 191 >UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase, putative glucose-1-dehydrogenase; n=1; Pyrococcus abyssi|Rep: Short-chain alcohol dehydrogenase, putative glucose-1-dehydrogenase - Pyrococcus abyssi Length = 240 Score = 75.8 bits (178), Expect = 9e-13 Identities = 58/202 (28%), Positives = 98/202 (48%), Gaps = 7/202 (3%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197 E K KV ITGA+ GIG ++ L GV + EE K + EL +YG +T Sbjct: 2 ELKGKVALITGASRGIGRAIAIELAKRGVNVVINYRSNEEEAKKTE-ELCRQYGVETLLV 60 Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM---NDSIGI----YKKAIEVNVTALI 356 ++DV++ E ++ V+ + G ID++INNA ++ D + + + + I VN+ Sbjct: 61 KADVSNREEVREMVKKVIDKFGRIDILINNAGILGKTKDPLEVTDEEWDRVISVNLKGAF 120 Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536 T + + M K G ++N++S+A V P Y A+K ++ + + R H + Sbjct: 121 IVTQEVLRYM------KKGKIVNIASIAGKDGGTVGPHYAASKGGLIALTFNLAR--HLA 172 Query: 537 KTGVRVLTVCFGATDTALLTDE 602 + V V G DT +L+ E Sbjct: 173 -PNILVNAVAPGPVDTDMLSSE 193 >UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Strongly similar to 3-oxoacyl-[acyl-carrier protein] reductase - Candidatus Kuenenia stuttgartiensis Length = 239 Score = 75.4 bits (177), Expect = 1e-12 Identities = 55/215 (25%), Positives = 106/215 (49%), Gaps = 7/215 (3%) Frame = +3 Query: 36 VFITGAATGIGESVVRILLDEG----VKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 + +TG + GIG+++ ++ + EG V H +D E+ L+ E +S G+ + ++ Sbjct: 1 MLVTGGSKGIGKAICKVFIGEGDHVIVNHCKPIDDIEK----LREEFSSPQGSFS-IEKA 55 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAI 377 DVTD +++ +V++ G IDV+INNA ++ D + A + N + +T Sbjct: 56 DVTDYAQIKQMVDNIVKKHGKIDVLINNAGIIKDGYIMLMSAKDWNDVINVNLTGVFNCT 115 Query: 378 EIMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554 + + +H G + GT+IN++S++ +T Y A K V+ F+ + + + +RV Sbjct: 116 KAVSEHMIGQRSGTIINIASLSGITGLPGQTNYSAAKGGVIAFTMALSK--ELAPFCIRV 173 Query: 555 LTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKK 659 TV G +T ++ + Y E L + K Sbjct: 174 NTVAPGVIETDIIDSLDKNKRNSYKEHIPLKRFGK 208 >UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4; Legionella pneumophila|Rep: Acetyoacetyl CoA reductase - Legionella pneumophila (strain Corby) Length = 248 Score = 75.4 bits (177), Expect = 1e-12 Identities = 50/172 (29%), Positives = 84/172 (48%), Gaps = 7/172 (4%) Frame = +3 Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE-EAGKSLQVELNSKYGNKTKFYRS 203 + VV ITG IG +V + LD KH+ LD+ + G+ +L ++ F Sbjct: 4 NNVVLITGGTGDIGTAVAK-QLDSTFKHVIALDLVSYDEGEVWLHDLKTQGYKNINFRHM 62 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 365 DVTD E ++ +++E GGIDV+INNA + D++ + + + VN+ + T Sbjct: 63 DVTDYEQCAEVIGLIIEEFGGIDVLINNAGITRDAVFTKMTKRQWDEVLRVNLDGMFNVT 122 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 521 + +E M G+ ++NVSSV A Y A+K+ V F+ + + Sbjct: 123 KQVVESMKVQESGR---IVNVSSVNAQKGQFSQANYAASKAGVYGFTKSLAQ 171 >UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=1; marine gamma proteobacterium HTCC2143|Rep: Short-chain dehydrogenase/reductase - marine gamma proteobacterium HTCC2143 Length = 264 Score = 75.4 bits (177), Expect = 1e-12 Identities = 58/200 (29%), Positives = 102/200 (51%), Gaps = 6/200 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 M++ + KV ITG +GIGE+ I + EG + + +EE G+++ ++ G+K Sbjct: 1 MTNRLQGKVAIITGGTSGIGEATADIYIKEGAT-VVLTGRSEEKGQAIA----NRLGDKA 55 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA----ALMNDSI--GIYKKAIEVNVTA 350 + ++DV+ EE ++ V+ G +DV+ NNA DSI G +++ +++ Sbjct: 56 HYIKADVSKEEDIANTISETVERFGKLDVLFNNAGGPVGGTIDSIAPGDINYGVDLLLSS 115 Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530 ++ AIE M K +G GG +IN +S+AA+ +Y A K+AV ++ G Sbjct: 116 VVLGIRYAIEPM-KANG--GGVIINNTSIAAIRYRQGNLLYSALKAAVTHYTKLAG--VE 170 Query: 531 FSKTGVRVLTVCFGATDTAL 590 G+RV + GA T + Sbjct: 171 LGPLGIRVNCISPGAIATPI 190 >UniRef50_A0X2J5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Shewanella pealeana ATCC 700345|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella pealeana ATCC 700345 Length = 254 Score = 75.4 bits (177), Expect = 1e-12 Identities = 56/191 (29%), Positives = 99/191 (51%), Gaps = 6/191 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 MS KV ITGAA G+G + R++ EG + + + DI E GK E+ + GN + Sbjct: 1 MSGRLIGKVALITGAARGVGLATARLMAREGAQ-VVLTDINAEQGK----EIANSIGNNS 55 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 350 F DVT E + ++N + + G +++++NNAA++ +++ +++ VN + Sbjct: 56 LFIEHDVTKEADWSAVINHIEAKFGQLNILLNNAAILQLGDIKEETLAGWQRVHMVNSDS 115 Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530 + A+ +M K SG GG++IN+SS +A+ Y A+K+A+ S + Sbjct: 116 VFLRIHYALPLMEK-SG--GGSIINMSSSSAVFGMPHFAAYGASKAAIRGLSQSVAVYCS 172 Query: 531 FSKTGVRVLTV 563 +K VR T+ Sbjct: 173 QTKNNVRCNTL 183 >UniRef50_Q9FX95 Cluster: ARP protein; n=8; Magnoliophyta|Rep: ARP protein - Arabidopsis thaliana (Mouse-ear cress) Length = 629 Score = 75.4 bits (177), Expect = 1e-12 Identities = 67/227 (29%), Positives = 108/227 (47%), Gaps = 20/227 (8%) Frame = +3 Query: 42 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGK---SLQVELNSKYGNKTKF-----Y 197 +TG A+GIG ++ L ++GV + + D +EE G+ SL E N+K+ F Sbjct: 11 VTGGASGIGRALCLALAEKGV-FVTVADFSEEKGQETTSLVREANAKFHQGLSFPSAIFV 69 Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN---------DSIGIYKKAIEVNVTA 350 + DVT+ L + + G +D+ INNA + D +K I V++ A Sbjct: 70 KCDVTNRGDLLAAFDKHLATFGTLDICINNAGISTPLRFDKDDTDGSKSWKHTINVDLIA 129 Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530 ++ T AI+ M K G +IN+ S A L V PIY A+K+ V+ F+ + + Sbjct: 130 VVEGTQLAIKAMKAKQ--KPGVIINMGSAAGLYPMPVDPIYAASKAGVVLFTRSLA---Y 184 Query: 531 FSKTGVRVLTVC--FGATDTALLTDEK-LGTFDKYLESSCLDQLKKG 662 + + G+R+ +C F TD A D L + Y+ +D L KG Sbjct: 185 YRRQGIRINVLCPEFIKTDLAEAIDASILESIGGYMS---MDMLIKG 228 >UniRef50_UPI0000E465C5 Cluster: PREDICTED: similar to MGC80593 protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to MGC80593 protein - Strongylocentrotus purpuratus Length = 258 Score = 74.9 bits (176), Expect = 2e-12 Identities = 55/186 (29%), Positives = 91/186 (48%), Gaps = 7/186 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 + V ITG+A G+G + + G + + +LDI E K L EL SK G Y D+ Sbjct: 63 RTVLITGSANGLGRLLAQEFARRGAQ-LVLLDIDIEGNKLLAEELCSK-GRSAHAYYCDL 120 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 371 + + ++ + ++ G +D++INNAA ++ S +K EVN A I T Sbjct: 121 SRKTDLYSVIAQIKRDIGHVDILINNAATLSGKPVLQCSDSAIEKVFEVNTMAYIWLTKA 180 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG-RPEHFSKTGV 548 + M K G V+N++S+A + + Y A+KSA++ F+ +G + TGV Sbjct: 181 LLPDMLNR---KQGHVVNIASLAGFVGVNGLADYCASKSAIIGFTEALGYELKQMKATGV 237 Query: 549 RVLTVC 566 + VC Sbjct: 238 HLSLVC 243 >UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative - Rhizobium meliloti (Sinorhizobium meliloti) Length = 249 Score = 74.9 bits (176), Expect = 2e-12 Identities = 58/194 (29%), Positives = 99/194 (51%), Gaps = 7/194 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K+ +TGA++GIG + L + G K + I + + L+ ++ +K G + DV Sbjct: 7 KIALVTGASSGIGAATAAKLAEAGAK-VGIAARRTDKLEDLKKKIEAK-GGEALVIEMDV 64 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALM--ND----SIGIYKKAIEVNVTALITSTLK 371 D + +V G ID+++NNA LM +D + +++ ++VNV L+ +T Sbjct: 65 VDTTSVEAGVKKLVDAYGSIDILVNNAGLMPLSDIDQFKVDEWQRMVDVNVKGLLNTTAA 124 Query: 372 AI-EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 + +++ +HS G V N+SS+A + +Y ATK AV FS+ + R E K G+ Sbjct: 125 VLPQMIKQHS----GHVFNMSSIAGRKVFKGLSVYCATKHAVTAFSDGL-RMEVGQKHGI 179 Query: 549 RVLTVCFGATDTAL 590 RV + GA T L Sbjct: 180 RVTCIQPGAVATEL 193 >UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Leptospira interrogans Length = 259 Score = 74.9 bits (176), Expect = 2e-12 Identities = 52/199 (26%), Positives = 100/199 (50%), Gaps = 7/199 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAAT--GIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN 182 MS +++ KV +TGAA+ G+G ++ + EG I ++D+ +E + ++ ++G Sbjct: 5 MSKQFEGKVALVTGAASPRGLGRAIANTIAKEG-GDIVLVDLNKEQIEQAAADVAKEFGV 63 Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITS 362 KT +VT E ++ V ++ G +D ++NNA ++ D++ I + E ++ Sbjct: 64 KTLGLSCNVTKPEDCDSVIAGVKEKFGKLDFLVNNAGVLKDNLFI--RMSEQEFDFVLDV 121 Query: 363 TLKAIEIMGKHSG-----GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527 LK + +M K++ + G ++N+SSV+ LT Y ++K+ V+ + R Sbjct: 122 NLKGVFLMTKYASKLLLKAESGRIVNISSVSGLTGQPGQANYSSSKAGVIALTKVAAR-- 179 Query: 528 HFSKTGVRVLTVCFGATDT 584 F+ V V VC G T Sbjct: 180 EFAGRNVLVNAVCPGYVQT 198 >UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain KSM-K16) Length = 257 Score = 74.9 bits (176), Expect = 2e-12 Identities = 53/189 (28%), Positives = 101/189 (53%), Gaps = 8/189 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K +TG A G+G ++ + L G IAI+DI EA E+ + Y T+ ++DV Sbjct: 12 KHAVVTGGAQGLGFTIAKSLAAFGCD-IAIVDIDAEAAAKAAQEITTTYSVNTQSIQADV 70 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMN--DSIGI----YKKAIEVNVTALITSTLK 371 + EE +++ V++ IDV++NNA ++ D++ + +K+ ++VN+ AL ++ + Sbjct: 71 SKEEEVSAMVDRVLESFPQIDVLVNNAGIVKKIDTLDMTYSDWKRTMDVNINALFLTSKQ 130 Query: 372 AIEIMGKHSGGKG-GTVINVSSVAA-LTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 +GKH G G+++N+SS++A + Y A+K AV + + +++ G Sbjct: 131 ----VGKHMVANGSGSIMNMSSMSAMIANREAQSAYNASKGAVSMLTKSLA--SEWAQYG 184 Query: 546 VRVLTVCFG 572 +RV + G Sbjct: 185 IRVNAIAPG 193 >UniRef50_Q2JG54 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=3; Frankia|Rep: Short-chain dehydrogenase/reductase SDR precursor - Frankia sp. (strain CcI3) Length = 291 Score = 74.9 bits (176), Expect = 2e-12 Identities = 58/195 (29%), Positives = 92/195 (47%), Gaps = 4/195 (2%) Frame = +3 Query: 42 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTDEE 221 ITGA++GIG + D G + + + +E + L ++YG + D+ DE Sbjct: 14 ITGASSGIGAAFAEAYADRGARLVLVAP-SEPRLWMVAERLGARYGTEAHVIAVDLADER 72 Query: 222 HFLGILNAVVQEQGGIDVVINNAALMN----DSIGIYKKAIEVNVTALITSTLKAIEIMG 389 + AV + +D+++NNA + + EV + + + + + G Sbjct: 73 GPDRLAEAVAEAGLEVDILVNNAGFGTRGPYHELSADRDHREVMLNVVAVERVAHLFLPG 132 Query: 390 KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCF 569 + G+G TVINVSS + M +Y A+K+ VL FS IG + + GVRVL +C Sbjct: 133 MVARGRG-TVINVSSTSGFQAVPYMTVYGASKAFVLSFS--IGLWAEYRRRGVRVLALCP 189 Query: 570 GATDTALLTDEKLGT 614 G TDT E LGT Sbjct: 190 GPTDTEFF--EVLGT 202 >UniRef50_Q1IPJ3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain dehydrogenase/reductase SDR - Acidobacteria bacterium (strain Ellin345) Length = 261 Score = 74.9 bits (176), Expect = 2e-12 Identities = 60/196 (30%), Positives = 93/196 (47%), Gaps = 7/196 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 +D+VV ITG GIG ++ R + EG I+ +E + + G + Sbjct: 28 EDQVVLITGGNRGIGLAMARAVAKEGAS--VIITGRDEHTLHHAADQIKRDGGTVVSHVC 85 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITS 362 DV DE+ + A+ + IDV++NNA L S+ ++ IE N+T Sbjct: 86 DVRDEDSVDELFAAIHRHYSQIDVLVNNAGLAQRNAQVDHLSLEAWQACIETNLTGAFLC 145 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 T A+ +M G TV+N SVAA T M Y A+K+ +L F+N + E Sbjct: 146 TRAALPMMSP-----GATVVNNVSVAANTAFPGMAAYSASKAGLLAFTNTL--REELRPR 198 Query: 543 GVRVLTVCFGATDTAL 590 G+RV+++ GATDT + Sbjct: 199 GIRVISLVPGATDTEI 214 >UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=4; Clostridiales|Rep: 7-alpha-hydroxysteroid dehydrogenase - Clostridium perfringens (strain SM101 / Type A) Length = 253 Score = 74.9 bits (176), Expect = 2e-12 Identities = 65/210 (30%), Positives = 99/210 (47%), Gaps = 10/210 (4%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 +S K+KVV +TG GIG + V+ LD G K +A+ +E ELN N Sbjct: 4 LSKSIKNKVVIVTGGTRGIGFATVKKFLDHGAK-VALCGSRKETVDKALEELNYINPNYD 62 Query: 189 KF-YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNV 344 + ++ D +++ V+++ G ID++INNA ++D+ IY K I++NV Sbjct: 63 AIGFYPNLLDSNEVKEMVDKVLEKWGTIDILINNAG-VSDNKSIYTQSDEDFSKIIDINV 121 Query: 345 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 524 A+ T EIM K G ++N SSV +L Y +K AV + + R Sbjct: 122 KAIFNCTKAVSEIM---KNKKYGVILNTSSVVSLYGQKTGVGYPTSKFAVNGLTKSLAR- 177 Query: 525 EHFSKTGVRVLTVCFG--ATDTALLTDEKL 608 + G+RV V G ATD D+KL Sbjct: 178 -ELGRDGIRVNAVAPGIIATDMVAALDKKL 206 >UniRef50_A6UZF9 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=16; Pseudomonas|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Pseudomonas aeruginosa PA7 Length = 266 Score = 74.9 bits (176), Expect = 2e-12 Identities = 55/197 (27%), Positives = 98/197 (49%), Gaps = 7/197 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 + ITGA++GIG ++ L G + + ++ +A +S+ EL ++G + F D+ Sbjct: 3 RYALITGASSGIGLALAEALARRG-RALILVARQRDALESIAYELAQRFGVEVLFRTCDL 61 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 371 + G+L+ + Q + ID+++NNA + ++ ++ IE+N+ AL + Sbjct: 62 AEPLQLSGLLHELEQGERQIDLLVNNAGIGSAGPFVDQEWAREQELIELNILALA----R 117 Query: 372 AIEIMGKHSGGKGG-TVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 +G +GG ++NV+SVAA M Y+A+K+ VL FS G E V Sbjct: 118 LCHALGTRMAAQGGGQILNVASVAAFQPGAWMSNYYASKAYVLHFSE--GLREELKARAV 175 Query: 549 RVLTVCFGATDTALLTD 599 +V +C G T TA + Sbjct: 176 KVSVLCPGPTRTAFFRE 192 >UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Arthrobacter aurescens TC1|Rep: Putative 3-oxoacyl-[acyl-carrier protein] reductase - Arthrobacter aurescens (strain TC1) Length = 261 Score = 74.9 bits (176), Expect = 2e-12 Identities = 55/194 (28%), Positives = 96/194 (49%), Gaps = 6/194 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K V +TGA +G+G +V + L EG I + D++E++ + + NS + +DV Sbjct: 9 KTVMVTGAGSGLGAAVFKRFLLEGANVIGV-DLSEDSMARFR-DRNSVLSGQITLKVADV 66 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 371 D + I+N V+E G +DV++NNA + S +++ ++VNV L +T Sbjct: 67 GDPDAIEAIINESVEELGALDVLVNNAGIAPTGPAATTSNELWRSVMKVNVDGLFYATRA 126 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 A+ H G ++N +SV+ + + Y A+K AV+ F+ + +++ GVR Sbjct: 127 AL----PHLIQSQGNIVNTASVSGIGADYNYAAYDASKGAVINFTRSVA--VDYAQRGVR 180 Query: 552 VLTVCFGATDTALL 593 V G T LL Sbjct: 181 CNAVAPGPVLTPLL 194 >UniRef50_A1BFL6 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Chlorobium/Pelodictyon group|Rep: Short-chain dehydrogenase/reductase SDR precursor - Chlorobium phaeobacteroides (strain DSM 266) Length = 280 Score = 74.9 bits (176), Expect = 2e-12 Identities = 58/199 (29%), Positives = 99/199 (49%), Gaps = 6/199 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K +TGAA+GIG ++ L++ G + + + DI + AG + G DV Sbjct: 8 KNAIVTGAASGIGFALAVGLIERGAR-VWVADI-DSAGVERAA---ASLGAGAHPVTLDV 62 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 371 D F ++ V ++ GGID + NNA +++ + I+VN+ ++ TL Sbjct: 63 RDAVAFRDLVAGVARDAGGIDFLFNNAGILHSGEVCEFDEEQCNRIIDVNIRGVVNGTLA 122 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 A +M + + G ++N +S+A L + ++ Y TK AV+ FS+ + R E + GVR Sbjct: 123 AYPLMVRQ---RSGHIVNTASLAGLAPAPLLSTYAMTKHAVVGFSSSL-RFE-AERYGVR 177 Query: 552 VLTVCFGATDTALLTDEKL 608 V +C DT LL +E + Sbjct: 178 VSAICPAGVDTPLLDEEAI 196 >UniRef50_A0VFC2 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Delftia acidovorans SPH-1|Rep: Short-chain dehydrogenase/reductase SDR - Delftia acidovorans SPH-1 Length = 301 Score = 74.9 bits (176), Expect = 2e-12 Identities = 62/201 (30%), Positives = 94/201 (46%), Gaps = 6/201 (2%) Frame = +3 Query: 3 LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN 182 +K ++ K V +TGA+ GIGE R L G K + I + K L EL Sbjct: 42 MKTPFDFSQKTVLVTGASMGIGEVFARELARRGAKVVLIARSRDRLEK-LASELPG---- 96 Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNV 344 +F D+ + +AV D+++NNA ++ + ++ I++NV Sbjct: 97 -AEFLVEDLATPGAARRVFDAVSARGLLPDLLVNNAGFGTHGRFDELALDMQRETIDLNV 155 Query: 345 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 524 AL+ T + + + GG VIN++S AA M +Y ATK+ VL FS + Sbjct: 156 GALVELTHLCLPALEQRQGG----VINIASTAAFQPVPYMAVYAATKAFVLSFSEALW-- 209 Query: 525 EHFSKTGVRVLTVCFGATDTA 587 + GVRVL +C GATDTA Sbjct: 210 AEYRPRGVRVLALCPGATDTA 230 >UniRef50_A0LZZ5 Cluster: Short-chain dehydrogenase/reductase family protein; n=1; Gramella forsetii KT0803|Rep: Short-chain dehydrogenase/reductase family protein - Gramella forsetii (strain KT0803) Length = 271 Score = 74.9 bits (176), Expect = 2e-12 Identities = 51/202 (25%), Positives = 104/202 (51%), Gaps = 6/202 (2%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197 ++++K V ITG A+GIG + + +++G + ILDI + A + ++++L + F Sbjct: 3 KFRNKTVLITGGASGIGLLLTKFSIEKGASALIILDIDKPALQQVELQLKTNICQILSF- 61 Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALIT 359 +D+++E + + + +D++INNA ++ ++ + ++VN A + Sbjct: 62 ETDLSNEIQIENAVKKITAQNLQVDILINNAGVVTGKNFSEHNLEDIDRNMQVNAIAPMK 121 Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539 T + M K K G ++N+SS A++ + M +Y A+K A+ +S+ + + Sbjct: 122 LTKLLLPEMLKR---KSGHIVNISSAASMLSNPGMSVYCASKWAMTGWSDSLRLEMERER 178 Query: 540 TGVRVLTVCFGATDTALLTDEK 605 TG++VLTV DT + K Sbjct: 179 TGIKVLTVTPYYIDTGMFEGVK 200 >UniRef50_Q2UEK6 Cluster: Dehydrogenases with different specificities; n=2; Aspergillus|Rep: Dehydrogenases with different specificities - Aspergillus oryzae Length = 261 Score = 74.9 bits (176), Expect = 2e-12 Identities = 56/203 (27%), Positives = 96/203 (47%), Gaps = 9/203 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV +TGA +GIG L + G ++ + + E GK +++++ G++ F +DV Sbjct: 13 KVAIVTGAGSGIGRETALCLANAGA-NVVVAEANETTGKETAAKVSAQTGSRGLFILTDV 71 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 368 + E ++ A ++ G +D+ +NNAAL D+ I ++K I VN+ + L Sbjct: 72 SRSESVQAMVIATIEAFGRLDIAVNNAALHPDASPIAELHEDHWQKIIGVNLVG-VAFCL 130 Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 K E+ G GG++IN+SS M Y A K + + + G+ Sbjct: 131 K-WELQQMIQQGGGGSIINISSATINRPQEKMSAYIAAKHGITGLTQTAAVEN--GRHGI 187 Query: 549 RVLTVCFG--ATDTALLTDEKLG 611 RV + G ATD + T ++LG Sbjct: 188 RVNALAPGGVATDLTMATMQELG 210 >UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplast precursor; n=80; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplast precursor - Arabidopsis thaliana (Mouse-ear cress) Length = 319 Score = 74.9 bits (176), Expect = 2e-12 Identities = 60/198 (30%), Positives = 97/198 (48%), Gaps = 8/198 (4%) Frame = +3 Query: 33 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELN-SKYGNKTKFYRSDV 209 VV ITGA+ GIG+++ L G K +++ A A ++ +V +YG + + DV Sbjct: 78 VVVITGASRGIGKAIALALGKAGCK--VLVNYARSAKEAEEVAKQIEEYGGQAITFGGDV 135 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 371 + ++ + + G IDVV+NNA + D++ I + + I +N+T + T Sbjct: 136 SKATDVDAMMKTALDKWGTIDVVVNNAGITRDTLLIRMKQSQWDEVIALNLTGVFLCTQA 195 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 A++IM K K G +IN+SSV L + Y A K V+ FS R V Sbjct: 196 AVKIMMKK---KRGRIINISSVVGLIGNIGQANYAAAKGGVISFSKTAAREGASRNINVN 252 Query: 552 VLTVCFGATD-TALLTDE 602 V+ F A+D TA L ++ Sbjct: 253 VVCPGFIASDMTAELGED 270 >UniRef50_P66778 Cluster: Probable oxidoreductase ephD; n=16; Mycobacterium|Rep: Probable oxidoreductase ephD - Mycobacterium bovis Length = 592 Score = 74.9 bits (176), Expect = 2e-12 Identities = 57/195 (29%), Positives = 91/195 (46%), Gaps = 6/195 (3%) Frame = +3 Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206 D +V +TGA +GIG EG + I I DI E K E+ ++ G Y D Sbjct: 324 DTLVSVTGAGSGIGRETALAFAREGAE-IVISDIDEATVKDTAAEIAAR-GGIAYPYVLD 381 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTL 368 V+D E V E G D+V+NNA + ++ + + + VN+ ++ Sbjct: 382 VSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNGCR 441 Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 + + + G GG ++NVSS+AA + Y +K+A FS+C+ R E GV Sbjct: 442 AFGQRLVER--GTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCL-RAE-LDAAGV 497 Query: 549 RVLTVCFGATDTALL 593 + T+C G DT ++ Sbjct: 498 GLTTICPGVIDTNIV 512 >UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase, putative; n=26; Gammaproteobacteria|Rep: 3-oxoacyl-(Acyl carrier protein) reductase, putative - Idiomarina loihiensis Length = 254 Score = 74.5 bits (175), Expect = 2e-12 Identities = 62/217 (28%), Positives = 97/217 (44%), Gaps = 15/217 (6%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 KD V+ ITG A G+G ++ +G K +A++DI + Q + K Y Sbjct: 4 KDSVIVITGGAQGLGLAMAEDFARQGAK-LALIDINGDVLGEAQEQCEKLGAAKVVGYEV 62 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI---------------YKKAIEV 338 D+TDEE + + QE GIDV++NNA L+ D + I ++ ++V Sbjct: 63 DITDEESVETVFEQIQQEFDGIDVLVNNAGLLRDGLLIKFKDGELKQKMPLQQFQSVLDV 122 Query: 339 NVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 518 N+T +A M K GK G +IN+SSVA + Y ATK+ V+ + Sbjct: 123 NLTGTFLCGREAAAQMVK--AGKKGVIINISSVAR-AGNMGQTNYSATKAGVVAMTVTWA 179 Query: 519 RPEHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYL 629 R + G+R + G +T + K D+ L Sbjct: 180 R--ELGRYGIRCGAIAPGFIETPMTAQMKPEAVDRAL 214 >UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1; Terrabacter sp. DBF63|Rep: Short-chain dehydrogenase/redutase - Terrabacter sp. DBF63 Length = 252 Score = 74.5 bits (175), Expect = 2e-12 Identities = 57/202 (28%), Positives = 94/202 (46%), Gaps = 7/202 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 MS+ KV +TG GIG ++L+D G + + + D++E+AG ++ G+ Sbjct: 1 MSNSLDGKVALVTGGGGGIGRETAKVLVDHGAR-VVVADLSEDAGNGTLEYIDG--GDAV 57 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVT 347 F R+DVTD ++ A V G +D+ NNA L + ++ + K I VN+T Sbjct: 58 AFVRADVTDLASMQHLVQAAVDRYGRLDIAHNNAGIEVTGPDLADVTVEQFDKVIAVNLT 117 Query: 348 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527 + S +KA EI + G GG++IN +S Y +K V+ + Sbjct: 118 GVFIS-MKA-EIPQMLAQG-GGSIINTASSLGQAALAHQSAYVTSKHGVIGLTRAAA--V 172 Query: 528 HFSKTGVRVLTVCFGATDTALL 593 +S G+RV V G T ++ Sbjct: 173 EYSDKGIRVNAVLPGVIQTPMI 194 >UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 256 Score = 74.5 bits (175), Expect = 2e-12 Identities = 58/200 (29%), Positives = 94/200 (47%), Gaps = 10/200 (5%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 +D+V ITGAA+G G + ++ EG K +A DI +E G VE + G + + Sbjct: 4 EDRVAVITGAASGQGRAAAKLFASEGAKVVAA-DI-DEGGAQRTVEEIKEAGGEATAVKV 61 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNV-----TALITSTL 368 DV+ E ++ + G +DV+ NNA + + G K A V A++ L Sbjct: 62 DVSREPDVRAMVESATDRYGRLDVLFNNAGVGYSASGRMKMASVVETPEKDWDAILAINL 121 Query: 369 KAIEIMGKHS----GGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533 K + + KH+ +G G++IN +S+ AL Y A K V+ FS + + Sbjct: 122 KGVALGCKHAIPVMERQGYGSIINNASINALVGLPGADAYTAAKGGVVAFSRVLA--VEW 179 Query: 534 SKTGVRVLTVCFGATDTALL 593 G+RV +C G DT ++ Sbjct: 180 GPRGIRVNCICPGGVDTPMI 199 >UniRef50_Q0GL61 Cluster: Short-chain dehydrogenase; n=3; Lactobacillus reuteri|Rep: Short-chain dehydrogenase - Lactobacillus reuteri Length = 277 Score = 74.5 bits (175), Expect = 2e-12 Identities = 66/195 (33%), Positives = 101/195 (51%), Gaps = 8/195 (4%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKY----GNKTK 191 +++VV ITG ++GIG+ L E + AI+ + + LQ E+ K G Sbjct: 12 RNEVVLITGGSSGIGKE----LAFEAARRGAIVVVVSRNLEKLQ-EVAKKCLILSGRPAF 66 Query: 192 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 371 Y+ DVTD + +L+ V E GGIDV+IN+A L D I + K++ + T+ L Sbjct: 67 AYQLDVTDPDQIDDVLSKVQHEVGGIDVLINSAGL-GDFIPVVKESYSSMEKMVHTNLLA 125 Query: 372 AIEI---MGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539 + I + K +G G +IN+ S+A + +Y ATK+ V+QF N + R E + Sbjct: 126 LMYISRCVAKQMMDQGYGAIINMGSLAGKLPTPNSAVYSATKAGVIQFDNVL-RME-VAD 183 Query: 540 TGVRVLTVCFGATDT 584 GV+VLTV G DT Sbjct: 184 YGVQVLTVNPGPIDT 198 >UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Enterobacter sp. 638|Rep: Short-chain dehydrogenase/reductase SDR precursor - Enterobacter sp. 638 Length = 242 Score = 74.5 bits (175), Expect = 2e-12 Identities = 59/200 (29%), Positives = 100/200 (50%), Gaps = 6/200 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 M+ E K +V +TGA++GIGE++ R L G++ + + E + V L S+ G+ Sbjct: 1 MNIEKKKRVAVVTGASSGIGEALARELAGNGIQVVLLARRFER----IDV-LASELGHGA 55 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 350 ++DVTD E + N V Q GG+D++INNA +M + + +++ +E N+ Sbjct: 56 IAIKADVTDRESIVAAANQVEQTLGGVDILINNAGVMLTGPFDSSQLDEHRQMVETNLLG 115 Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530 +T T E+ G ++N+SSVA +Y ATK + +S + R E Sbjct: 116 AMTVT----EVFLPQLRRNKGDLVNISSVAGRVAPSGFAVYAATKWGINGWSEAL-RVE- 169 Query: 531 FSKTGVRVLTVCFGATDTAL 590 + +RV+ + GA T L Sbjct: 170 -LQPDIRVMVIEPGAIATEL 188 >UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x; n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase FadB2x - Pseudomonas stutzeri (strain A1501) Length = 258 Score = 74.5 bits (175), Expect = 2e-12 Identities = 67/221 (30%), Positives = 101/221 (45%), Gaps = 17/221 (7%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 +DKVV ITG A+G+G + L E IAI D+ EAG+ L ++ + F + Sbjct: 4 QDKVVVITGGASGLGLATAHYLAAEKGARIAIFDLNVEAGEQAVAALGTE---RAMFVAT 60 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-----------SIGIYKKAIEVNVTA 350 DV+ EE ++AV+ G I V IN AA+ + + +A +N+ Sbjct: 61 DVSSEESVQNAVDAVMANFGAIHVCINGAAVPTGFKILGKEGKAAPLARFAQATAINLNG 120 Query: 351 LITSTLKAIEIMGKH---SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 521 + K E M K+ +G + G VINVSS AA Y ATK+ V+ + R Sbjct: 121 VFNVMSKCAEHMAKNEAEAGEERGVVINVSSGAAYEGQLGQCAYSATKAGVIGLNMPAAR 180 Query: 522 PEHFSKTGVRVLTVC---FGATDTALLTDEKLGTFDKYLES 635 GVRV + F T A L ++ LG+ + +E+ Sbjct: 181 --ELGAIGVRVNAIAPGLFLTTMVAALDEKVLGSLKEQMEA 219 >UniRef50_A5BP77 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 387 Score = 74.5 bits (175), Expect = 2e-12 Identities = 58/209 (27%), Positives = 103/209 (49%), Gaps = 20/209 (9%) Frame = +3 Query: 63 IGESVVRILLDEGVKHIAILDIAEEAGK---SLQVELNSKYGNK-----TKFYRSDVTDE 218 IG+++ L ++G+ + ++D +EE GK SL + N+K+ K F R DVT+ Sbjct: 36 IGKAISLALGEKGI-FVTVVDFSEEGGKEVASLVEKENAKFHPKLGFPSAMFIRCDVTNT 94 Query: 219 EHFLGILNAVVQEQGGIDVVINNAAL---------MNDSIGIYKKAIEVNVTALITSTLK 371 + GG+D+ +N+A + ++ G++++ I VN+ A+I T Sbjct: 95 RELAAAFKKHLATYGGLDICVNSAGIGTHEPFHKDQTENSGLWRRTINVNLVAVIDCTRL 154 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 AI+ M + K G +IN+ S + L +V PIY A+K V+ F+ + + + G+R Sbjct: 155 AIQTM--QAAKKPGVIINMGSASGLYPMYVDPIYSASKGGVVLFTRSLA---PYKRHGIR 209 Query: 552 VLTVC--FGATDTALLTDEK-LGTFDKYL 629 V +C F T+ D K +G Y+ Sbjct: 210 VNVLCPEFVQTEMGSSVDSKFIGLMGGYV 238 >UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 284 Score = 74.5 bits (175), Expect = 2e-12 Identities = 67/220 (30%), Positives = 100/220 (45%), Gaps = 19/220 (8%) Frame = +3 Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE--EAGKSLQVELNSKYGNKTKFYR 200 DKV ITG++ GIG++ R+L EG K AE E K++ + GN Sbjct: 6 DKVAIITGSSNGIGQATARLLASEGAKVTVTGRNAERLEETKNILLGAGVPEGN-VLVVV 64 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL----------MNDSIGIYKKAIEVNVTA 350 D+T E ++ + + + G ID+++NNA +N SI Y K E+NV + Sbjct: 65 GDITQESVQENLIKSTLDKFGKIDILVNNAGAGIPDAQGKSGVNQSIDTYHKTFELNVQS 124 Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHV-MPIYFATKSAVLQFSNCIGRPE 527 +I T KA H G ++N+SS+ A + V P Y K+A+ Q++ Sbjct: 125 VIEMTQKA----RPHLAKTQGEIVNISSIGAGPAAQVASPYYSIAKAALDQYTRTAA--I 178 Query: 528 HFSKTGVRVLTVCFGATDTAL------LTDEKLGTFDKYL 629 G+RV +V GA T LT+EK F YL Sbjct: 179 DLVPEGIRVNSVSPGAVSTGFSAVSRGLTEEKSKAFYDYL 218 >UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Burkholderiaceae|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 252 Score = 74.1 bits (174), Expect = 3e-12 Identities = 51/182 (28%), Positives = 91/182 (50%), Gaps = 6/182 (3%) Frame = +3 Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206 +KV +TGAA+G+G + +L EG + + + DI E+AG++L E+ G+ F R D Sbjct: 6 NKVALVTGAASGVGRADALLLAAEGAR-VVLTDIDEDAGRALAREI----GDAALFVRHD 60 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 368 + DE + + + + G +DV++NNAA+ + S+ +++ + N Sbjct: 61 IADEAGWQHAIASTLDRFGRLDVLVNNAAICPVGSIEDTSLDTWRRVMRTNADGYFLGCK 120 Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 AI M G+++ +SSVAAL +M Y +K AV + + H ++G Sbjct: 121 YAIGAM--KGNDTPGSIVMMSSVAALGGLPMMCAYTGSKGAVTALARSVA--VHCKRSGY 176 Query: 549 RV 554 R+ Sbjct: 177 RI 178 >UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain dehydrogenase/reductase SDR precursor - Acidobacteria bacterium (strain Ellin345) Length = 271 Score = 74.1 bits (174), Expect = 3e-12 Identities = 56/199 (28%), Positives = 92/199 (46%), Gaps = 4/199 (2%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 M + KV +TG A GIGE+ R + G +AILD E+AG + + +G + Sbjct: 1 MKIDLSGKVAVVTGGAMGIGEACARKIALAGAS-VAILDPNEDAGTKTAAAIRA-HGGEC 58 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 368 KF+R DV+ + + V+ + ID++++NA + G E + +I L Sbjct: 59 KFFRCDVSKSKDVEQAVGDVITKHSQIDILVSNAGI--QYYGDVITTPEDDWDRVIGVNL 116 Query: 369 KAIEIMGK----HSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536 K ++ K H GG ++ + SV + T Y +K AVL + + ++ Sbjct: 117 KGCFLISKFCVPHMISNGGAIVVLGSVQSFTAIQNSAAYVTSKHAVLGLARAMAL--DYA 174 Query: 537 KTGVRVLTVCFGATDTALL 593 G+RV VC G DT +L Sbjct: 175 HKGIRVNCVCPGTIDTPML 193 >UniRef50_A6CTS3 Cluster: Putative uncharacterized protein; n=1; Bacillus sp. SG-1|Rep: Putative uncharacterized protein - Bacillus sp. SG-1 Length = 260 Score = 74.1 bits (174), Expect = 3e-12 Identities = 61/202 (30%), Positives = 95/202 (47%), Gaps = 7/202 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 K+KVV ITGA++G+G + + + +E+ +L EL K+G K Sbjct: 2 KNKVVVITGASSGLGVEFAKQFAGRSYD-LVLTARSEDKLNNLAKELEGKHGIKAHVIPI 60 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL----MNDSIGIYKKA--IEVNVTALITST 365 D++ + VV +++INNA + I K+ IEVN+TAL T Sbjct: 61 DLSQHGSAKTLHEKVVSLGLTTEILINNAGFGLFGEFEDTDIQKEVDMIEVNITALTELT 120 Query: 366 LKAIEIMGKHSG-GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 + GK G G ++NV+SVAA +M +Y+ATK+ VL S + + Sbjct: 121 ----KYFGKEMVVGNTGKILNVASVAAFQPGPLMAVYYATKAYVLSLSEALS--NEWKDK 174 Query: 543 GVRVLTVCFGATDTALLTDEKL 608 GV+V +C GAT+T +L Sbjct: 175 GVKVSVLCPGATETGFSNSAEL 196 >UniRef50_A4XF64 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Novosphingobium aromaticivorans (strain DSM 12444) Length = 266 Score = 74.1 bits (174), Expect = 3e-12 Identities = 56/191 (29%), Positives = 90/191 (47%), Gaps = 4/191 (2%) Frame = +3 Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206 ++ +TGAA GIGE + R EG + + D +E G ++ +L G + +F R D Sbjct: 8 NRAAVVTGAADGIGEGIARRFAAEGAA-VVVADYDDERGPAVARDLRG-LGARAEFIRCD 65 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTAL---ITSTLKAI 377 V+ E +G ++ V+ G +D+++NNA + I KK E AL + +T A+ Sbjct: 66 VSRREDVIGAVDLCVERFGSVDILVNNAYRGEGPVRIEKKTDERFDEALRMCLFATKWAM 125 Query: 378 EIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554 E H KG G VIN++S+ + Y K AV +S R ++ G+ V Sbjct: 126 ERALPHMKAKGWGRVINMASLNGVNAHMGSADYNVAKEAVRAYSRTAAR--EWAPYGICV 183 Query: 555 LTVCFGATDTA 587 +C A A Sbjct: 184 NVICPAAVSAA 194 >UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1; Flavobacteriales bacterium HTCC2170|Rep: Probable glucose 1-dehydrogenase - Flavobacteriales bacterium HTCC2170 Length = 268 Score = 74.1 bits (174), Expect = 3e-12 Identities = 53/198 (26%), Positives = 93/198 (46%), Gaps = 5/198 (2%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 K K V +TG + GIG + R L G + + E++ + L E+++ YG +T + Sbjct: 7 KGKRVLVTGGSRGIGAEICRKLAACGAEVFINYNSNEQSAQDLANEISNSYGVRTGIACA 66 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 383 DV+ E + + GGID+++NNA +SI +E +I LK + Sbjct: 67 DVSKAEQVKQMFLKMDGVMGGIDILVNNAG--TESIHHVLDLVEEEWDRVINVNLKGPFL 124 Query: 384 MGKHSGGK-----GGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 K +G + GG +IN+SS+ + + Y + K+ + S C+ ++ + Sbjct: 125 CSKEAGDRMEKNGGGVIINISSIHDVVPRKGLIHYCSAKAGLKMLSKCLSL--ELAENNI 182 Query: 549 RVLTVCFGATDTALLTDE 602 RV++V GA T + DE Sbjct: 183 RVVSVAPGAISTEMNRDE 200 >UniRef50_Q2U0U8 Cluster: Dehydrogenases with different specificities; n=2; Pezizomycotina|Rep: Dehydrogenases with different specificities - Aspergillus oryzae Length = 271 Score = 74.1 bits (174), Expect = 3e-12 Identities = 58/215 (26%), Positives = 101/215 (46%), Gaps = 23/215 (10%) Frame = +3 Query: 33 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN------KTKF 194 + ITGAA+GIG + +G IA+LD+ + A +++Q E+NS+ + + Sbjct: 6 IALITGAASGIGRACAHTFARDGASGIALLDLDKTALETVQAEINSQSSQDKTARCRVEI 65 Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGI-------YKKAIEVNVTA 350 Y +VTDE ++N+ Q +D V+N A + M G +++ ++VN+T Sbjct: 66 YPVNVTDENRVDEVINSAAQTFSRLDYVVNAAGIAMKHQGGAAFAETSDWQRILDVNLTG 125 Query: 351 LITSTLKAIEIMGKHS------GGK---GGTVINVSSVAALTQSHVMPIYFATKSAVLQF 503 A IM G+ G+++N SS+ + + Y ATK AV+ Sbjct: 126 TFFVLRAAARIMLSQEPIRSSIDGRPLQRGSIVNFSSIQGVAGIPLSTAYTATKHAVIGL 185 Query: 504 SNCIGRPEHFSKTGVRVLTVCFGATDTALLTDEKL 608 + E ++K G+R+ +C G T+T + T L Sbjct: 186 TRTAS--EDYAKDGLRINAICPGYTETPMTTKSPL 218 >UniRef50_Q5UYC2 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=2; Halobacteriaceae|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Haloarcula marismortui (Halobacterium marismortui) Length = 254 Score = 74.1 bits (174), Expect = 3e-12 Identities = 56/211 (26%), Positives = 98/211 (46%), Gaps = 9/211 (4%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE---EAGKSLQVELNSKYGNKTKF 194 +DKV +TG A+G G ++ R + G + + D + E GK + ++ F Sbjct: 6 EDKVAVVTGGASGFGRAICRRYAEHGA-DVIVADRQQDPREGGKPTHELVEAETDRTAHF 64 Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALI 356 DVTD + L + A +E GGID+++NNA + + Y + ++VN + Sbjct: 65 VECDVTDPDD-LEVAVAAAEELGGIDIMVNNAGISEIADFYETTEEDYDRLMDVNTKGVF 123 Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536 A E M ++ GGTVIN+SS + + ++ Y +K AV F+ + + S Sbjct: 124 FGAQVATEAMRENG---GGTVINMSSSGGIRGTGLLVNYCTSKGAVRLFTYALA--DRLS 178 Query: 537 KTGVRVLTVCFGATDTALLTDEKLGTFDKYL 629 +RV + G + T + DE++ K + Sbjct: 179 NYNIRVNAIHPGYSKTQMFEDERIDDTTKMM 209 >UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=225; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Vibrio cholerae Length = 244 Score = 74.1 bits (174), Expect = 3e-12 Identities = 59/201 (29%), Positives = 97/201 (48%), Gaps = 9/201 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV +TGA+ GIG+++ +L + G K I E+G ++ G+ K +V Sbjct: 6 KVALVTGASRGIGKAIAELLAERGAKVIGTA--TSESGAQA---ISDYLGDNGKGMALNV 60 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK------AIEVNVTALITSTLK 371 T+ E +L A+ E GG+D+++NNA + D++ + K +E N+T++ + Sbjct: 61 TNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLSKA 120 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 + M K + G +INV SV + Y A K+ V+ F+ + R + GV Sbjct: 121 VLRGMMKK---RQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAR--EVASRGVT 175 Query: 552 VLTVC--FGATD-TALLTDEK 605 V TV F TD T L DE+ Sbjct: 176 VNTVAPGFIETDMTKALNDEQ 196 >UniRef50_Q7M9W0 Cluster: 3-OXOACYL-REDUCTASE; n=24; Epsilonproteobacteria|Rep: 3-OXOACYL-REDUCTASE - Wolinella succinogenes Length = 247 Score = 73.7 bits (173), Expect = 4e-12 Identities = 44/166 (26%), Positives = 82/166 (49%), Gaps = 6/166 (3%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197 ++ K V ITG++ GIG + R+L + G+K L+ E+ +K G + Sbjct: 2 KFSGKNVLITGSSRGIGADIARVLAEMGLKVWINYRSQSSLADELKAEIEAK-GGQAAVI 60 Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALIT 359 D TDEE F+ + ++ G + ++NNA + ND + I ++ IE N+T+ Sbjct: 61 SFDATDEEAFISGIKTIIDADGELAYLVNNAGITNDKLAIRMKTEEFRSVIEANLTSAFI 120 Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVL 497 + +A++ M K + G+V+N+SS+ + Y A+K ++ Sbjct: 121 GSREALKSMSKQ---RFGSVVNISSIVGERGNAGQTNYSASKGGMI 163 >UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chain dehydrogenase/reductase family; n=1; Photobacterium profundum|Rep: Hypothetical oxidoreductase, short-chain dehydrogenase/reductase family - Photobacterium profundum (Photobacterium sp. (strain SS9)) Length = 255 Score = 73.7 bits (173), Expect = 4e-12 Identities = 54/194 (27%), Positives = 89/194 (45%), Gaps = 7/194 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV I+G +GIGE+ R+ +G + ++ E G+ L ELN++Y T F ++D+ Sbjct: 10 KVALISGITSGIGEATARLFSQQGAS-LVLVARNENKGQMLAEELNAQY--PTLFIKADI 66 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 368 T + + E GGID NNA + S I+ + I N+ Sbjct: 67 TQANQVDQVFEQTMAEFGGIDCAFNNAGIDGSKQPISETSDEIWNQIINTNLNGTWNMLN 126 Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 + + IM K GT++N++S+ ++ Y ++ AVL + ++K GV Sbjct: 127 RQLSIMSKQG---HGTIVNMASICSVLARPNRAAYNTSRHAVLGLTR--SAAVEYAKQGV 181 Query: 549 RVLTVCFGATDTAL 590 RV V GA DT + Sbjct: 182 RVNAVAPGAIDTPI 195 >UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacillus thuringiensis Length = 247 Score = 73.7 bits (173), Expect = 4e-12 Identities = 50/196 (25%), Positives = 98/196 (50%), Gaps = 6/196 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV +TG A GIG+++ L EG K + + ++EA ++L EL K G+ ++DV Sbjct: 7 KVAIVTGGAKGIGKAITVALAQEGAKVVINYNSSKEAAENLVNEL-GKEGHDVYAVQADV 65 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 371 + E ++ V G +D+++NNA + D + +++ I+VN++++ +T Sbjct: 66 SKVEDANRLVEEAVNHFGKVDILVNNAGITRDRTFKKLNREDWERVIDVNLSSVFNTTSA 125 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 + + + + G +I++SS+ Y A K+ +L F+ + +KT V Sbjct: 126 VLPYI---TEAEEGRIISISSIIGQAGGFGQTNYSAAKAGMLGFTKSLAL--ELAKTNVT 180 Query: 552 VLTVCFGATDTALLTD 599 V +C G DT ++ + Sbjct: 181 VNAICPGFIDTEMVAE 196 >UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reductase; n=1; Bacillus sp. SG-1|Rep: 3-oxoacyl-(Acyl-carrier-protein) reductase - Bacillus sp. SG-1 Length = 246 Score = 73.7 bits (173), Expect = 4e-12 Identities = 54/195 (27%), Positives = 96/195 (49%), Gaps = 6/195 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 K+K ITG+A GIG + + EG K + + D E G + + E + G T FY+ Sbjct: 4 KNKTAVITGSANGIGLAAAKKFAQEGCK-VIMADYDENKGAA-EAEKLQEEGGDTVFYQV 61 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITST 365 DV + E + V+++ G ID++INNA + D++ +++ ++VN+T + T Sbjct: 62 DVANRESVDNLAAWVLRDYGSIDILINNAGITRDALMAKMREDDFQRVLDVNLTGVFHCT 121 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 + + + GK G +IN +S + L + Y A+K+AV+ + + F G Sbjct: 122 QALLPAL--INSGK-GKIINTASASGLYGNVGQTNYAASKAAVIGMTKTWAK--EFGPKG 176 Query: 546 VRVLTVCFGATDTAL 590 + V V G +T + Sbjct: 177 INVNAVAPGVIETEM 191 >UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like protein; n=1; Reinekea sp. MED297|Rep: Short-chain alcohol dehydrogenase-like protein - Reinekea sp. MED297 Length = 672 Score = 73.7 bits (173), Expect = 4e-12 Identities = 51/169 (30%), Positives = 90/169 (53%), Gaps = 8/169 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KVV ITG ++GIG++ L G I AE+ ++ +++ S G +++D+ Sbjct: 385 KVVLITGGSSGIGKATAMRLSKAGATVIICARDAEKLRRA-HLDIESTGGTVVS-HQADI 442 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNA------ALMN--DSIGIYKKAIEVNVTALITST 365 T + + + +E G+D++INNA ++M D + +++ IE+N A + T Sbjct: 443 TQPDDVDRLFGMIEREFAGLDILINNAGHSIRRSVMQSLDRLHDFQRTIELNYLASVAIT 502 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNC 512 LKA+ +M + + G VIN+SS+ L+ S Y A+K+A+ FS C Sbjct: 503 LKALPMMDRR---REGHVINISSIGVLSNSPRFSAYVASKAALEAFSRC 548 >UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Marinomonas sp. MED121|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MED121 Length = 255 Score = 73.7 bits (173), Expect = 4e-12 Identities = 58/207 (28%), Positives = 101/207 (48%), Gaps = 7/207 (3%) Frame = +3 Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200 +KD+VV ITGA+ G+G+ + +G K +A+ D+ A L EL + G + Sbjct: 4 FKDQVVLITGASGGLGKEAAKQFAQQGAK-LALCDLNVAALNDLGTEL-IEQGYEVFSQP 61 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNA-------ALMNDSIGIYKKAIEVNVTALIT 359 DV++E+ ++ G +DV INNA L + +++ +++NV + Sbjct: 62 CDVSNEQEVQSFIDNTAAHFGRLDVAINNAGIDPKHSTLADMDTRDFERVMDINVKGVYL 121 Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539 I M K GG + N+SSVA ++ + M Y A+K AV+ + + + + Sbjct: 122 CMKYQIPHMIKQG---GGAICNMSSVAGISGAPFMSAYAASKHAVIGLTKSVA--HEYGR 176 Query: 540 TGVRVLTVCFGATDTALLTDEKLGTFD 620 G+RV +VC T T ++ ++ L T D Sbjct: 177 AGIRVNSVCPYITMTDMV-EQHLKTLD 202 >UniRef50_A2U319 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Polaribacter dokdonensis MED152|Rep: Short-chain dehydrogenase/reductase SDR - Polaribacter dokdonensis MED152 Length = 259 Score = 73.7 bits (173), Expect = 4e-12 Identities = 60/193 (31%), Positives = 96/193 (49%), Gaps = 8/193 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K ITGA++G+G+ +I G + I+ +++ + L+ +L K+G D+ Sbjct: 3 KTALITGASSGLGKEFAKIHAKNG-GDLVIVARSKDKLQKLKEKLEKKHGVHVSIIEKDL 61 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG-IYKKA-------IEVNVTALITST 365 T+ + N V + ID +INNA IG +++A I++N+ AL T Sbjct: 62 TEPNAAQEVYNFVKFSKIEIDYLINNAGF--GGIGKFHERAWAQDLAMIQLNIIALTDLT 119 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 K + + + GK ++NVSS A+L + +YFATK+ V FSN I H +K Sbjct: 120 RKFLPDFVERNQGK---ILNVSSTASLMAGPMQAVYFATKAFVTSFSNAIAEELHDTK-- 174 Query: 546 VRVLTVCFGATDT 584 V V T+ GAT T Sbjct: 175 VTVTTLMPGATKT 187 >UniRef50_UPI00015B4F48 Cluster: PREDICTED: similar to ENSANGP00000025535; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to ENSANGP00000025535 - Nasonia vitripennis Length = 254 Score = 73.3 bits (172), Expect = 5e-12 Identities = 58/201 (28%), Positives = 100/201 (49%), Gaps = 8/201 (3%) Frame = +3 Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200 W KV +TGA+ GIG ++V LLD G + ++ +A K ++ ++ + K Sbjct: 4 WAGKVAVVTGASVGIGAAIVNKLLDNG---LIVVGLARRVEKVKEL-IDDRPEAKLHAVE 59 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITS 362 DVT+EE+ + + + G +DV++NNA L + S+ ++ ++VNV L Sbjct: 60 CDVTNEENVVTAFAWIKENLGSVDVLVNNAGVTKETTLSDGSLADWRNVLDVNVLGLCVC 119 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHV--MPIYFATKSAVLQFSNCIGRPEHFS 536 T +A+ M + G +I++SS+A V +Y ATK AV + + R E + Sbjct: 120 TREAVRSMRECDG--ESVIIHISSLAGERVPAVPGFNVYPATKRAVNALAQTL-RHE-LA 175 Query: 537 KTGVRVLTVCFGATDTALLTD 599 T +RV T+ G T L+ + Sbjct: 176 GTKIRVTTISPGLVATELMAN 196 >UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 248 Score = 73.3 bits (172), Expect = 5e-12 Identities = 57/193 (29%), Positives = 93/193 (48%), Gaps = 5/193 (2%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV ITGA +GIG ++ R+ EG K + + D+A E G +L L + G+ F DV Sbjct: 7 KVAVITGAGSGIGAAIARLFAVEGAK-VLLGDLA-EGGAALAAGLAAD-GHAAGFQHVDV 63 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 389 TDE ++ A V G +D+++ NA + I++ + V+ +I L + I Sbjct: 64 TDEASVAELMQAAVTLFGRLDILVANAGIPERKSPIHELDL-VDWRRVIDVDLTGVAICN 122 Query: 390 KHSGG-----KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554 K + G GG ++N++S+ A Y A K+AV+ + + ++ G+R Sbjct: 123 KFAAGIMRATGGGAIVNMASILAHVGQENSNAYSAAKAAVVNLTRSVALT--YALQGIRA 180 Query: 555 LTVCFGATDTALL 593 V G DT LL Sbjct: 181 NCVSPGYVDTPLL 193 >UniRef50_Q3IVD0 Cluster: Short-chain alcohol dehydrogenases; n=2; Rhodobacteraceae|Rep: Short-chain alcohol dehydrogenases - Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM158) Length = 247 Score = 73.3 bits (172), Expect = 5e-12 Identities = 60/201 (29%), Positives = 98/201 (48%), Gaps = 6/201 (2%) Frame = +3 Query: 36 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 215 + ITGA +GIG R EG +A++D E A QV + G+ + DVTD Sbjct: 10 IVITGAGSGIGRESARQFAREGAT-LALIDRDEAAA---QVTADETGGH---VFALDVTD 62 Query: 216 EEHFLGILNAVVQEQGGIDVVINNAALMN----DSIGI--YKKAIEVNVTALITSTLKAI 377 E ++ + GGID ++N+A ++ D IG+ +++ ++VN+T A+ Sbjct: 63 EAAVETVVGRAAEALGGIDGLLNSAGILTMKTVDDIGVEEFRRVVDVNLTGTFLVCQAAL 122 Query: 378 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557 + K ++N++S AL S Y A+K+AV+ FS I + VRV Sbjct: 123 PWLRKE---PKAAIVNIASAQALLPSLTGSAYAASKAAVMMFSKSIAKE---LAPAVRVN 176 Query: 558 TVCFGATDTALLTDEKLGTFD 620 +C GAT+T +TD+ + D Sbjct: 177 IICPGATETP-MTDQGVAPDD 196 >UniRef50_Q3VZL7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 261 Score = 73.3 bits (172), Expect = 5e-12 Identities = 62/200 (31%), Positives = 92/200 (46%), Gaps = 11/200 (5%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197 E KV ITG G G++ L + G H+ + DI + + EL + G+ T Sbjct: 14 EHAGKVALITGGGRGFGKAFGAALTERGA-HVVLADIDGDVASAAAAELTALGGSATGV- 71 Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI---------GIYKKAIEVNVTA 350 DVTDE ++ +V+ GG+D+++NNA L + + G ++ EVNV Sbjct: 72 TCDVTDEARVGEVVADIVRAHGGLDILVNNAGLHSAAFNKPTAELGAGQIRRLFEVNVMG 131 Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530 ++ TL A + M SG G V+N+SS AA Y +K AV F+ R Sbjct: 132 VVICTLAAKDAM---SGRAGAAVVNISSSAAYAN---RTAYGVSKLAVRGFTAQFAR--E 183 Query: 531 FSKTGVRVLTVCFG--ATDT 584 + GVRV + G TDT Sbjct: 184 LAAVGVRVNAIAPGLILTDT 203 >UniRef50_Q03X86 Cluster: Putative uncharacterized protein; n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293|Rep: Putative uncharacterized protein - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 247 Score = 73.3 bits (172), Expect = 5e-12 Identities = 63/201 (31%), Positives = 98/201 (48%), Gaps = 9/201 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV+ ITGA++GIGE++ + G K I + EE K ++ ++ + G + ++ +DV Sbjct: 5 KVIVITGASSGIGEAIAKKQAAAGDK-IVLGARREENLKQIKADIEAG-GGQAEYLVTDV 62 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 371 TD E + + G IDV INNA LM S+ I + + I+VN+ + Sbjct: 63 TDVEQVKALAQKAMDAYGRIDVWINNAGLMPHSLLIDARIDDWNRMIDVNLKGTLYGIAA 122 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 A I + G IN+ SVA+L +Y ATK AV S + E + VR Sbjct: 123 AQHIFHDQNTGH---FINLGSVASLYSHAGGAVYSATKWAVKAISESLREEEAQAGKNVR 179 Query: 552 VLTVCFGATDTAL---LTDEK 605 V ++ GA ++ L +TD K Sbjct: 180 VTSLYPGAIESELVANMTDSK 200 >UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5; Proteobacteria|Rep: Short chain dehydrogenase - Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) Length = 278 Score = 73.3 bits (172), Expect = 5e-12 Identities = 62/201 (30%), Positives = 89/201 (44%), Gaps = 7/201 (3%) Frame = +3 Query: 12 SHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK 191 S+E V ITGA TGIG + EG + +A+ EEAG +L EL + GN+ + Sbjct: 27 SNEMNTPTVLITGALTGIGRATAFAFAREGYR-VAVSGRREEAGNALAAELRA-LGNEAE 84 Query: 192 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTA 350 F +DV E ++ V G IDV +NNA ++ S Y + VNV Sbjct: 85 FLLADVRFEADVRNLVEQTVVRFGRIDVAVNNAGTEGQLAPIVEQSAANYAETFGVNVLG 144 Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530 + S + +M G++IN+SSVA +Y A+K AV + Sbjct: 145 TMLSLKHEMRVMLAQG---SGSIINLSSVAGKVGIAGASVYVASKHAVEGLTKSAAL--E 199 Query: 531 FSKTGVRVLTVCFGATDTALL 593 + GVRV V G T +L Sbjct: 200 GAAAGVRVNAVAPGPVATEML 220 >UniRef50_Q8FA17 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=3; Leptospira|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Leptospira interrogans Length = 247 Score = 72.9 bits (171), Expect = 6e-12 Identities = 50/189 (26%), Positives = 88/189 (46%), Gaps = 2/189 (1%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 K+K V +TG+ GIG EG K+ I G S Q + G+ K + + Sbjct: 8 KNKTVLVTGSTRGIGRYFA-----EGFKNAGA--IVYGTGSS-QESIKKFDGSGIKGFAA 59 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAI 377 D+ + I+ ++V+E G +DV++NNA + ++ + K E+ + T +A Sbjct: 60 DIRQPDVMTPIIESIVKEHGRLDVLVNNAGIASNKPAAFLKEDEIESIIQTNFTGVFRAC 119 Query: 378 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557 K KGG +IN++S+ + + + +Y TK AV+ + + + +G RV Sbjct: 120 TAYYKIHKKKGGNIINIASILGMRGTKLASVYSGTKGAVINMTRALA--VEWIGSGYRVN 177 Query: 558 TVCFGATDT 584 +C G DT Sbjct: 178 AICPGFIDT 186 >UniRef50_Q0VL04 Cluster: Oxidoreductase, putative; n=1; Alcanivorax borkumensis SK2|Rep: Oxidoreductase, putative - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 581 Score = 72.9 bits (171), Expect = 6e-12 Identities = 55/194 (28%), Positives = 97/194 (50%), Gaps = 7/194 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K V ITGA +GIG G + DI E + + ++ G + + DV Sbjct: 315 KRVIITGAGSGIGRETALAFARRGAL-VVCTDINSEEAAATARTITAE-GGEALSRKCDV 372 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALIT-STL 368 ++ + V +E G D+V+NNA +L++ S+ +++ + VN+ +I S L Sbjct: 373 SNTRSMEALATWVEKELGAPDIVVNNAGIGLSGSLLDTSVKDWQQVLGVNLWGVIHGSRL 432 Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 A +++ + G+ G ++N++S AA S ++P Y +KSAVL FS C+ R E + + Sbjct: 433 FARQMIDQ---GRAGHIVNIASAAAFMPSRMLPAYATSKSAVLMFSECL-RAE-MDEHNI 487 Query: 549 RVLTVCFGATDTAL 590 V +C G +T + Sbjct: 488 GVSAICPGIINTPI 501 >UniRef50_Q0S5L2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=3; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus sp. (strain RHA1) Length = 258 Score = 72.9 bits (171), Expect = 6e-12 Identities = 52/184 (28%), Positives = 87/184 (47%), Gaps = 6/184 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K + +TG A GIG ++V+ EG + D+ EE G+ + E + +F R D+ Sbjct: 6 KRILVTGGAQGIGAAIVKAYAMEGAT-VRSYDLNEEGGRVVAEEASDAGPGVVEFSRLDI 64 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG------IYKKAIEVNVTALITSTLK 371 TD + + + +E GGIDV++N A L ++ +++ VNV I + Sbjct: 65 TDGDATESLFRSAARELGGIDVLVNIAGLQRSAMAEEITDDLFESIYRVNVLGTIHTNQS 124 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 A IM S G G +IN S++ T Y ++K AV ++ + R + +G+R Sbjct: 125 AYRIM--QSAGT-GAIINFGSMSGFTGELANATYGSSKGAVHTWTRTVAR--EWGPSGIR 179 Query: 552 VLTV 563 V V Sbjct: 180 VNAV 183 >UniRef50_A7IMM1 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Xanthobacter autotrophicus Py2|Rep: Short-chain dehydrogenase/reductase SDR precursor - Xanthobacter sp. (strain Py2) Length = 261 Score = 72.9 bits (171), Expect = 6e-12 Identities = 57/201 (28%), Positives = 97/201 (48%), Gaps = 8/201 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 KDK + ITGAA GIG ++ + L +G + I + D++E A +++ E+ + G Sbjct: 5 KDKSIVITGAAGGIGAAIAKALAADGAR-ITVADLSEPAARAVAGEITAA-GGTAIAVAV 62 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 365 DV +L+ V G +DV+ NNA + ++ + ++ +VN ++ Sbjct: 63 DVRQRAQVRALLDEAVAAHGRLDVLFNNAGVAQTRPFLDITEDDWRFVTDVNALGVLIGM 122 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 +AI+ K GG GG ++N +S+AA + Y A+K AV+ + R F K Sbjct: 123 QEAIKTF-KRQGG-GGKIVNTASIAAKQGYEPLAHYCASKFAVVALTQAAARA--FGKDQ 178 Query: 546 VRVLTVCFG--ATDTALLTDE 602 + V C G ATD + D+ Sbjct: 179 ITVNAFCPGVVATDMWKIIDK 199 >UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=1; Marinomonas sp. MED121|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Marinomonas sp. MED121 Length = 259 Score = 72.9 bits (171), Expect = 6e-12 Identities = 58/185 (31%), Positives = 90/185 (48%), Gaps = 6/185 (3%) Frame = +3 Query: 36 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 215 V +TG A+GIGE++V+ L +G ++ DI EEAG+ L LNS +G K F D+TD Sbjct: 20 VLVTGGASGIGEALVKALAQQGCA-VSFFDIDEEAGEQLAQNLNS-HGMKAHFELVDLTD 77 Query: 216 EEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLKAI 377 E + A ++ G I ++NNAA L S + + + VN+ + K Sbjct: 78 IEMLKDKIQARLEAWGAIRALVNNAANDHRHTLAELSSDEFDQCMAVNLKHHFFAAQKVA 137 Query: 378 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557 +M + GG++IN+SS + + P Y K+ + + + R T VRV Sbjct: 138 PLMAE---AGGGSIINMSSNSWMLGLSGYPGYVTAKAGISGLTKALAR--ELGPTKVRVN 192 Query: 558 TVCFG 572 TV G Sbjct: 193 TVLPG 197 >UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Verminephrobacter eiseniae EF01-2|Rep: Short-chain dehydrogenase/reductase SDR - Verminephrobacter eiseniae (strain EF01-2) Length = 265 Score = 72.9 bits (171), Expect = 6e-12 Identities = 55/197 (27%), Positives = 94/197 (47%), Gaps = 6/197 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV ITGA +GIG + + EG + I + D+ E G++ V + G + F ++DV Sbjct: 16 KVALITGAGSGIGRATALLFATEGAQ-IVVCDLDPEGGQAT-VRAIEQAGAQALFVQADV 73 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 371 + ++ +DV+ NNA + ++ S + + VNV ++ + + Sbjct: 74 AQAADCARAVQQTLRHFARLDVLFNNAGITCRANVVDTSEADWDAVMAVNVKSIFLMSRQ 133 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 A+ +M + GG ++IN S L Y A K AV+ + + +H + +R Sbjct: 134 AVPVMAEQGGG---SIINAGSGWGLVGGRDAVSYCAAKGAVVNMTRAMAL-DHGPQR-IR 188 Query: 552 VLTVCFGATDTALLTDE 602 V +VC G TDTA+L DE Sbjct: 189 VNSVCPGDTDTAMLRDE 205 >UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627; n=13; Bacteria|Rep: Uncharacterized oxidoreductase SSP1627 - Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 /DSM 20229) Length = 246 Score = 72.9 bits (171), Expect = 6e-12 Identities = 66/222 (29%), Positives = 103/222 (46%), Gaps = 7/222 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 200 KDKVV ITGA++GIGE V +L + G K L + L+ ++ K G + + Sbjct: 5 KDKVVVITGASSGIGEETVNLLSENGAK----LVLGARRLDRLE-KIQQKVGHDSVSIKK 59 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 362 +DVT + ++ + G IDV+INNA LM S + + I+VN+ ++ Sbjct: 60 TDVTKPDEVNALIETAYNDFGRIDVLINNAGLMPQSFLEKNKQDEWNQMIDVNIKGVLYG 119 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 + M K K G +IN++SVA +Y TK AV + + + E + Sbjct: 120 IGAVLPYMRKQ---KSGHIINLASVAGHVVFPGSAVYCGTKYAVRAITEGLRQEEAIVGS 176 Query: 543 GVRVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKKGFI 668 +R + GA T LTD DK ++ +D+L K I Sbjct: 177 NIRTTILSPGAVSTE-LTDH---ISDKDMKQD-IDELYKNAI 213 >UniRef50_P50197 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=8; root|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Pseudomonas paucimobilis (Sphingomonas paucimobilis) Length = 250 Score = 72.9 bits (171), Expect = 6e-12 Identities = 51/195 (26%), Positives = 94/195 (48%), Gaps = 7/195 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K + +TG +GIG + V +L+ G ++ + DI +EAG+++ + G K ++R D+ Sbjct: 7 KTIIVTGGGSGIGRATVELLVASGA-NVPVADINDEAGEAVV----ATSGGKAAYFRCDI 61 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 368 EE ++ + GG+D NNAA L S+ +++++++NVT T Sbjct: 62 AQEEDVKALVAQTLAAFGGLDGSFNNAAIPQAGLPLAEVSLERFRQSMDINVTG--TFLC 119 Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 +I+ G G+++N +S A + + Y K AV+ + + K G+ Sbjct: 120 MKYQILAMIERGTKGSIVNTASAAGVVGVPMHGEYVGAKHAVVGLTRVAA--ADYGKHGI 177 Query: 549 RVLTVCFGATDTALL 593 RV + GA T +L Sbjct: 178 RVNALVPGAVRTPML 192 >UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60; Bacteria|Rep: Sorbitol dehydrogenase - Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides) Length = 256 Score = 72.9 bits (171), Expect = 6e-12 Identities = 52/188 (27%), Positives = 95/188 (50%), Gaps = 4/188 (2%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K ITG+A GIG + + EG + +AI DI EA ++ E+ G DV Sbjct: 6 KTALITGSARGIGRAFAEAYVREGAR-VAIADINLEAARATAAEI----GPAACAIALDV 60 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDS--IGIYKKAIEVNVTALITSTLKAIEI 383 TD+ + ++ G ID+++NNAAL + + + I +++ + ++ TL ++ Sbjct: 61 TDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFMMQA 120 Query: 384 MGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557 + + +GG+GG +IN++S A ++ +Y ATK+AV+ + G + + G+ V Sbjct: 121 VARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGL--NLIRHGINVN 178 Query: 558 TVCFGATD 581 + G D Sbjct: 179 AIAPGVVD 186 >UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oceanobacillus iheyensis|Rep: Hypothetical conserved protein - Oceanobacillus iheyensis Length = 254 Score = 72.5 bits (170), Expect = 8e-12 Identities = 60/197 (30%), Positives = 93/197 (47%), Gaps = 7/197 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KVV ITG A GIG++ ++LLD G K +A++DI E++ + L+ + ++ +V Sbjct: 4 KVVLITGGAGGIGQATAKLLLDYGAK-VALVDINEDSLVKAKESLHVE-DDRVFTITGNV 61 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 368 T EE + V G IDV NNA + I ++K + +NVT + Sbjct: 62 TVEEDVENYVKQTVDRFGKIDVFFNNAGVNGPVSPITELDQATFEKIMSINVTGVFLGLK 121 Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 ++ M K G+++N +S AA S M Y A+K AV + + G+ Sbjct: 122 HVMKQMKKQG---YGSIVNTASNAAYIGSAGMVSYIASKHAVAGITKTAAL--EVASDGI 176 Query: 549 RVLTVCFGATDTALLTD 599 RV V A DT +L D Sbjct: 177 RVNAVAPAAIDTQMLAD 193 >UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular organisms|Rep: Alcohol dehydrogenase - Bordetella parapertussis Length = 252 Score = 72.5 bits (170), Expect = 8e-12 Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 5/195 (2%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K +TGA +G GE + EG K + + DI E G+ + +N+ G + F R+DV Sbjct: 6 KTAIVTGAGSGFGEGIAATFAREGAK-VVVADINEAGGQRVAAAINAA-GGQAVFVRADV 63 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 389 +D +L A ++ GG+D+V+NNA + + + + E + +K+I + Sbjct: 64 SDNAAVANLLAATLKAFGGLDIVVNNAGTTHRNRPML-EVEEDEFDRIYAINVKSIYLTA 122 Query: 390 KH-----SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554 +H GG+ IN++S AA+ + Y +K AV+ S + V Sbjct: 123 RHMVPHFRAHGGGSFINIASTAAIRPRPGLTWYNGSKGAVVTTSKSMAAELGPDNIRVNC 182 Query: 555 LTVCFGATDTALLTD 599 + GA T LL D Sbjct: 183 VNPVIGA--TGLLAD 195 >UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase precursor; n=2; Clostridium difficile|Rep: Probable short chain dehydrogenase precursor - Clostridium difficile (strain 630) Length = 245 Score = 72.5 bits (170), Expect = 8e-12 Identities = 50/216 (23%), Positives = 103/216 (47%), Gaps = 6/216 (2%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 K K V ITG A GIG+++ + EG + + +E K L LN K K +++ Sbjct: 2 KKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKELYTILNEK-NFSVKLFKA 60 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 365 ++++ E +++ ++E GG+DV++NNA + D + + + +N+ + Sbjct: 61 NISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITDEDWDNMMNINLKGSFYCS 120 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 A++ M K G +IN+SS+ ++ + Y TK+ ++ + + + + Sbjct: 121 QVALKYM---ISEKKGNIINISSIWGISGASCEVHYSITKAGIIGMTKALAK--EVGPSN 175 Query: 546 VRVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQL 653 +RV ++ G +T +L+ D +E + L +L Sbjct: 176 IRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRL 211 >UniRef50_O33454 Cluster: P-cumic alcohol dehydrogenase; n=3; Proteobacteria|Rep: P-cumic alcohol dehydrogenase - Pseudomonas putida Length = 252 Score = 72.5 bits (170), Expect = 8e-12 Identities = 60/194 (30%), Positives = 93/194 (47%), Gaps = 9/194 (4%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 KDKV +TGAATGIG ++VR L EG K + I D+ + ++ EL + + Sbjct: 4 KDKVAIVTGAATGIGNAIVRSYLAEGAK-VVIADV--KGAEAAAAELGE---DLALGVFA 57 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN-------DSIGI--YKKAIEVNVTALI 356 DV+D + + A + G IDV++NNA + +SI + + K VNV Sbjct: 58 DVSDPDSTKQMAKAALDRFGKIDVLVNNAGIFTGLNYVPMESISVADWDKLYSVNVKG-- 115 Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536 L A + G GG +IN++SV A + M Y ++K AV + + R + Sbjct: 116 -PWLCASAVSAAMREGGGGKIINIASVIAHIGAPFMLHYVSSKGAVAAMTRAMAREFATT 174 Query: 537 KTGVRVLTVCFGAT 578 K G+ V ++ G T Sbjct: 175 KAGISVNSISPGYT 188 >UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Roseiflexus sp. RS-1 Length = 246 Score = 72.5 bits (170), Expect = 8e-12 Identities = 58/196 (29%), Positives = 92/196 (46%), Gaps = 5/196 (2%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 K KV +TGA GIG++ EG H+A++DI AG V ++ + ++ Sbjct: 4 KGKVAIVTGAGHGIGKATAIAFAREGA-HVAVVDI-NMAGAEATVAEITRLDGRALAVQA 61 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 383 DV+ ++ V+ G IDV++NNA + D+ + K E A+I LK + + Sbjct: 62 DVSQAASVESMVETVLAWGGRIDVLLNNAGITRDARLV--KMTEQQWDAVINVNLKGVWL 119 Query: 384 MGK----HSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 + H +G G++INVSS+ L + Y ATK V+ + R +GV Sbjct: 120 CARAVAPHMSAQGSGSIINVSSIVGLYGNFGQSNYAATKGGVIAMTKTWAR--ELGPSGV 177 Query: 549 RVLTVCFGATDTALLT 596 RV V G T ++T Sbjct: 178 RVNAVTPGFIATEMIT 193 >UniRef50_Q0D3V4 Cluster: Os07g0664000 protein; n=34; cellular organisms|Rep: Os07g0664000 protein - Oryza sativa subsp. japonica (Rice) Length = 572 Score = 72.5 bits (170), Expect = 8e-12 Identities = 58/197 (29%), Positives = 88/197 (44%), Gaps = 9/197 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV ITG A+GIG++ + G K + I DI ++ G S+ EL G + R DV Sbjct: 314 KVAVITGGASGIGKATATEFIKNGAK-VIIADIQDDLGHSVAAEL----GPDAAYTRCDV 368 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNA----ALMND-----SIGIYKKAIEVNVTALITS 362 DE + V+ G +DV NNA AL D +G + + + VN + + + Sbjct: 369 ADEAQVAAAVGLAVKRHGRLDVFHNNAGIAGALPQDDMAAVDLGDFDRVMAVNARSTLAA 428 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 A M G V+ SS A + +P+Y +K+ V+ P ++ Sbjct: 429 VKHAARAMAPRC---SGCVLCTSSGAGVIPVPAVPVYSVSKATVIAIVRAAAEP--MARH 483 Query: 543 GVRVLTVCFGATDTALL 593 G+RV + GAT T LL Sbjct: 484 GLRVNAISPGATRTPLL 500 >UniRef50_Q9VU92 Cluster: CG8757-PA; n=3; Drosophila melanogaster|Rep: CG8757-PA - Drosophila melanogaster (Fruit fly) Length = 266 Score = 72.5 bits (170), Expect = 8e-12 Identities = 58/216 (26%), Positives = 102/216 (47%), Gaps = 13/216 (6%) Frame = +3 Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200 W +KV ++GA+ GIG + R L+ G+ + + E K L+ L+ + ++ + Sbjct: 18 WCNKVAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEK-LRSGLSLEQQSRLHAIK 76 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALM-------NDSIGIYKKAIEVNVTALIT 359 D+T E+ L + ++ GG+DV+++NA ++ D + IE N+ + Sbjct: 77 CDITQEDQVLKAFDWTCRQLGGVDVLVSNAGIIGTGELSERDDGPAMRSTIETNIMGTVY 136 Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMP------IYFATKSAVLQFSNCIGR 521 ++ M K G +G VI V+SVA ++ P IY ATK A+ + + Sbjct: 137 CVRESFRSM-KRRGTEGHVVI-VNSVAGYQVPNLGPQLPSLNIYPATKFALRAMNEIYRQ 194 Query: 522 PEHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYL 629 KT VRV TV G DT +L ++ G +++ Sbjct: 195 EFQRHKTAVRVSTVSPGIVDTVILPEQIQGIIKQHM 230 >UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Acidobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Acidobacteria bacterium (strain Ellin345) Length = 257 Score = 72.1 bits (169), Expect = 1e-11 Identities = 53/193 (27%), Positives = 93/193 (48%), Gaps = 3/193 (1%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV + G TGIG ++ L D G ++ E+ + E+ + G +T SDV Sbjct: 10 KVAVVVGGTTGIGRAISFGLADAGADVVSTARREEQVNAAAD-EIERR-GRQTLRVCSDV 67 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAIEI 383 T + NAV+ + +D+++N A + + E N + +T L+A ++ Sbjct: 68 TSRASIQSLCNAVLAKFQKVDILVNCAGTTKRTPTLTVSEDEWNKILDTNLTGALRACQV 127 Query: 384 MGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560 GKH +G G +IN++S+++ H + Y A+K+A+L + + +SK GV V Sbjct: 128 FGKHMIERGYGRIINIASLSSFVALHEVAAYSASKAALLSLTRSLA--VEWSKKGVTVNA 185 Query: 561 VCFGATDTALLTD 599 + G TAL T+ Sbjct: 186 IAPGVFRTALNTE 198 >UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 251 Score = 72.1 bits (169), Expect = 1e-11 Identities = 58/203 (28%), Positives = 95/203 (46%), Gaps = 6/203 (2%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K +TGA +GIG ++ EG + +A+ D+ E A + + E+ G R+DV Sbjct: 7 KRTIVTGAGSGIGRAIALRFAAEGAR-VALADVDEGAARKVAAEI----GEGCLVQRTDV 61 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 371 T E G++ + GG++V++NNA + S +++ + VN+ Sbjct: 62 TVAEEVEGLVRLATERWGGLEVMVNNAGVGVAATAPQTSEEDFERVLAVNLRGTFLGMKY 121 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 AI + + SG GG VIN+SS+AAL Y A K +L + G +H + GVR Sbjct: 122 AIPAI-RDSG--GGAVINMSSIAALVGLKDRAAYSAAKGGILALTRA-GAIDHIHE-GVR 176 Query: 552 VLTVCFGATDTALLTDEKLGTFD 620 V + G +T ++ G D Sbjct: 177 VNCIAPGTVETPWISRITAGYAD 199 >UniRef50_Q13H99 Cluster: Putative short-chain dehydrogenase/reductase; n=3; Proteobacteria|Rep: Putative short-chain dehydrogenase/reductase - Burkholderia xenovorans (strain LB400) Length = 274 Score = 72.1 bits (169), Expect = 1e-11 Identities = 53/201 (26%), Positives = 98/201 (48%), Gaps = 12/201 (5%) Frame = +3 Query: 6 KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNK 185 K + ++KV +TGA G+G + R L G + +A++DI EA ++ ++ G + Sbjct: 5 KAGGKLENKVAIVTGAGAGLGAACARALAQHGAR-VAVVDINGEAAAAVAADI----GER 59 Query: 186 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------------SIGIYKKA 329 R+DV+ E +++AV++ G ID++ NNAA+++D S+ ++ +A Sbjct: 60 AMSVRTDVSSEAQVKAMVSAVLEHFGRIDILHNNAAVLDDAQRAGDRDVINMSVEVWDRA 119 Query: 330 IEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 509 + VN+ + AI M + G GG++I+ SS M Y A+K+ + S Sbjct: 120 MAVNLRGAMLCCKHAIPAMLR---GGGGSIIHSSSGFGAQGDFTMSAYAASKAGLAMLSK 176 Query: 510 CIGRPEHFSKTGVRVLTVCFG 572 + + K +R T+ G Sbjct: 177 SVA--AQYGKERIRSNTIQIG 195 >UniRef50_Q0M0K7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caulobacter sp. K31|Rep: Short-chain dehydrogenase/reductase SDR - Caulobacter sp. K31 Length = 249 Score = 72.1 bits (169), Expect = 1e-11 Identities = 54/200 (27%), Positives = 95/200 (47%), Gaps = 6/200 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 MS + +V +TGA++G GE+V L G K +A+ E+ ++L + G + Sbjct: 1 MSMDLSGRVALVTGASSGFGEAVALDLAKAGAK-VALAARREDRLRALAQRITDA-GGQA 58 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 350 + +D TDE + G +D++INNA +M +G ++ +E+N+ Sbjct: 59 QVIVADFTDEHQAQRAVRETEAAFGWLDILINNAGVMYLEPVATADLGRWRSMLELNLLG 118 Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530 LI +T A+ M + K G ++N++S A + + Y A+K V+ FS + + H Sbjct: 119 LIAATQAALPGM---TARKDGHIVNIASTAGHIANPLSAAYSASKFGVIGFSESLRKEVH 175 Query: 531 FSKTGVRVLTVCFGATDTAL 590 K +RV + G T L Sbjct: 176 --KDNIRVTVISPGMAATEL 193 >UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Parvibaculum lavamentivorans DS-1|Rep: Short-chain dehydrogenase/reductase SDR - Parvibaculum lavamentivorans DS-1 Length = 287 Score = 72.1 bits (169), Expect = 1e-11 Identities = 56/195 (28%), Positives = 95/195 (48%), Gaps = 8/195 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV ITG +GIG V + L EG K +A D+ + G++++ EL G + R++V Sbjct: 7 KVAIITGGTSGIGRGTVDLFLKEGAKVVAA-DLQDHKGEAMEREL----GENFSYCRANV 61 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN-----VTALITSTLKA 374 E+ +++ V++ G +D++ NNA +G + I++N V L+ + Sbjct: 62 AHEDEVKNLVDHTVKKFGKLDILFNNAGY--GGVGGELQEIDMNGFDETVGVLLKGVVLG 119 Query: 375 IEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNC--IGRPEHFSKTG 545 + H K G++I+ +SVA L + +Y A K+AV FS C + HF Sbjct: 120 YKYAVPHMKAQKSGSIISTASVAGLQAGYGPLVYSACKAAVHHFSRCAALELAPHF---- 175 Query: 546 VRVLTVCFGATDTAL 590 VR +C G T++ Sbjct: 176 VRSNAICPGGIATSI 190 >UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Gammaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella sp. (strain ANA-3) Length = 253 Score = 72.1 bits (169), Expect = 1e-11 Identities = 60/206 (29%), Positives = 96/206 (46%), Gaps = 8/206 (3%) Frame = +3 Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206 +K +TGAA GIG++++R LL EG + +A A+ + +L+V N +K + D Sbjct: 5 NKTAVVTGAAGGIGQAIIRKLLAEGARVVA----ADLSADALKV-FNDFPADKLVTFSVD 59 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITST 365 VTD + ++ + G +D++INNA L +D I ++ VN + Sbjct: 60 VTDYKQVEAMVKHAADQFGQLDILINNAGIGLAKPLLQHDPINDFEPVTNVNQKGVYHGI 119 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 L + G G ++N SSV A S + Y +K+AV + C + G Sbjct: 120 LAGGRQF--QAQGSRGVILNTSSVYAQIASEMTFTYNVSKAAVDMMTKCAAL--ELAPLG 175 Query: 546 VRVLTVCFGATDTALLTD-EKLGTFD 620 VRV V G DT +L E LG ++ Sbjct: 176 VRVCAVAPGRVDTPMLRQYEALGLWE 201 >UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Shewanella woodyi ATCC 51908|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella woodyi ATCC 51908 Length = 255 Score = 72.1 bits (169), Expect = 1e-11 Identities = 50/191 (26%), Positives = 94/191 (49%), Gaps = 6/191 (3%) Frame = +3 Query: 36 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 215 VFITG A+GIG ++VR +++G ++ +D +AG++L L+ G + F+ DVTD Sbjct: 15 VFITGGASGIGAALVRAFVEQGA-NVTFVDTNRDAGEALLQGLDINRGQQVAFHLLDVTD 73 Query: 216 EEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGI----YKKAIEVNVTALITSTLKAI 377 + ++ Q+ G +D++INN +D+ G+ +K+ + +N+ + ++ A Sbjct: 74 TKQLQQMITEQDQKLGQLDILINNVGNDSRHDADGVDEHEWKQCMAINLDSAFFASQAAY 133 Query: 378 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557 +M + K G +IN SS A M Y K+ + + + + S+ V + Sbjct: 134 LVMKQR---KQGVIINFSSNMAYIGERNMAGYITAKAGIAGMTKALAKDYGESRVRVNAI 190 Query: 558 TVCFGATDTAL 590 + AT L Sbjct: 191 VPGWVATQRQL 201 >UniRef50_Q54D03 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 292 Score = 72.1 bits (169), Expect = 1e-11 Identities = 53/197 (26%), Positives = 93/197 (47%), Gaps = 6/197 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV F+TG A+GIG +V + EG K +AI+D+ + + ELN ++ T DV Sbjct: 36 KVCFVTGGASGIGLGIVERFVKEGGK-VAIVDLDKTKADNASKELNQRFPGSTISVECDV 94 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 371 ++EE + V+ GG+DV+++NA L + + ++K + V++ T Sbjct: 95 SNEEQVSKGIKDTVERFGGLDVIVSNAGLQHIETLETVELATWRKMMAVHLDGAFLCTKY 154 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 A++ K +GGT++ + SV + S Y K + C G +K +R Sbjct: 155 AMQEF-KKDIKRGGTILYMGSVHSKYASEYKIPYVTAKHGLEGL--CRGVAREGAKHNIR 211 Query: 552 VLTVCFGATDTALLTDE 602 +C G T L+ ++ Sbjct: 212 ANLICPGFVLTPLVKNQ 228 >UniRef50_Q22RI1 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=3; Oligohymenophorea|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Tetrahymena thermophila SB210 Length = 260 Score = 72.1 bits (169), Expect = 1e-11 Identities = 58/219 (26%), Positives = 108/219 (49%), Gaps = 18/219 (8%) Frame = +3 Query: 33 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 209 V +TG +G+GE+ V LL++GV+ + I D EE G +++ +KYG ++ +F + DV Sbjct: 8 VALVTGGTSGLGEATVYALLEKGVR-VFIADRNEEKG----LQIQTKYGQDRCRFQKCDV 62 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------------YKKAIEVNVTA 350 +DE +++A V G I +++N+A +++ + + + + VNV Sbjct: 63 SDEAQVKALVDACVATFGAIHILLNSAGVISAGLIVGGKNQDQTIKTEEMNRVLGVNVVG 122 Query: 351 LITST----LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 518 T L+ ++ + + G ++NV+SVA + +Y A+K A++ + + Sbjct: 123 TFNVTKYVALQMVKQQPLNEFKERGVIVNVASVAGIEGQRGQTVYAASKGAIIGMTLPLA 182 Query: 519 RPEHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYLES 635 R K GVRV T+ G T + G DK +E+ Sbjct: 183 R--DLGKFGVRVCTIAPGIFQTPM----GAGMSDKIIEA 215 >UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; n=28; Bacteria|Rep: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase - Mycobacterium bovis Length = 260 Score = 72.1 bits (169), Expect = 1e-11 Identities = 55/200 (27%), Positives = 98/200 (49%), Gaps = 6/200 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 MS KV ++G A G+G S VR ++ EG K + DI +E GK++ EL + Sbjct: 1 MSGRLIGKVALVSGGARGMGASHVRAMVAEGAK-VVFGDILDEEGKAVAAEL----ADAA 55 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTA 350 ++ DVT + ++ V GG+ V++NNA ++N ++ +++ ++VN+T Sbjct: 56 RYVHLDVTQPAQWTAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTG 115 Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530 + ++ M K +G G++IN+SS+ L + Y ATK AV + Sbjct: 116 VFLGIRAVVKPM-KEAG--RGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTAL--E 170 Query: 531 FSKTGVRVLTVCFGATDTAL 590 +G+RV ++ G T + Sbjct: 171 LGPSGIRVNSIHPGLVKTPM 190 >UniRef50_UPI00015B572E Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 240 Score = 71.7 bits (168), Expect = 1e-11 Identities = 44/152 (28%), Positives = 78/152 (51%), Gaps = 4/152 (2%) Frame = +3 Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQ---VELNSKYGN-KTKF 194 +KV +T GIG S + L +++A+LD+ + + L ++G K + Sbjct: 5 NKVAIVTDGLGGIGFSTYLLRLK--AQYVAVLDLPQNNSPHVVDGLKTLEEEFGKGKFGY 62 Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 374 Y +V + E F + VV+ +G +D+++ NAA+ D+ I+VN+ +I TL A Sbjct: 63 YHVNVANAESFAAVYAKVVEHKGYVDILVYNAAVAKDTE--IDLTIDVNLKGVIKGTLHA 120 Query: 375 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPI 470 +E MG H KGG V+N++S L + + + Sbjct: 121 VEQMGVHKNQKGGVVVNIASFLGLEHNKFLGV 152 >UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n=2; Bacillaceae|Rep: 2O-beta-hydroxysteroid dehydrogenase - Oceanobacillus iheyensis Length = 244 Score = 71.7 bits (168), Expect = 1e-11 Identities = 62/219 (28%), Positives = 108/219 (49%), Gaps = 10/219 (4%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 ++KV ITG A G+G S VR+ EG K + D+ EE G +L EL G KF + Sbjct: 5 ENKVAIITGGARGMGASHVRLFAKEGAK-VVFTDLNEEGGLALANEL----GENVKFVKQ 59 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 365 DVT+ + + +++ + G ++V++NNA LM + Y+K I++N ++ Sbjct: 60 DVTNADDWETVISETEEAFGPVNVLVNNAGISLSIPLMEMTEEQYRKIIDINQVSVFLG- 118 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 +KA+ + +G G+++N+SS+ + V Y +K AV + G Sbjct: 119 MKAVVPSMQKAG--SGSIVNISSMNGIVAGAVG--YTDSKFAVRGATKAAA--VQLGGLG 172 Query: 546 VRVLTVCFGATDTALLTD----EKLGTFDKYLESSCLDQ 650 +RV +V G +T ++T E++ F K + S + Q Sbjct: 173 IRVNSVHPGVIETPMVTKGDAVEQIKEFAKQIPSKRMAQ 211 >UniRef50_Q5LMX2 Cluster: 20-beta-hydroxysteroid dehydrogenase, putative; n=25; Alphaproteobacteria|Rep: 20-beta-hydroxysteroid dehydrogenase, putative - Silicibacter pomeroyi Length = 250 Score = 71.7 bits (168), Expect = 1e-11 Identities = 58/202 (28%), Positives = 93/202 (46%), Gaps = 8/202 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 K K V ITGA+ GIG R+ G ++ +L + EA + E+ G++ Sbjct: 5 KGKTVLITGASRGIGAEAGRVFAQAGA-NVVLLARSAEALAAQAAEI----GDRALALAC 59 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM--------NDSIGIYKKAIEVNVTALIT 359 DV D G +NA V GG+DV+INNA ++ +D +G + AI++N+ + Sbjct: 60 DVADAAQVAGAVNAAVSRFGGLDVLINNAGVIEPISHLASSDPVG-WGHAIDINLKGVYY 118 Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539 A+ +M K GGT++ VSS AA Y A+K+ + C+ E Sbjct: 119 GMRAALPVMRK---AGGGTILTVSSGAAHNPVEAWSHYCASKAGAAMLTACLHLEE--GH 173 Query: 540 TGVRVLTVCFGATDTALLTDEK 605 G+R + + G T + + K Sbjct: 174 HGIRAMGLSPGTVATQMQREIK 195 >UniRef50_Q11ZZ1 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Polaromonas sp. JS666|Rep: Short-chain dehydrogenase/reductase SDR - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 265 Score = 71.7 bits (168), Expect = 1e-11 Identities = 58/209 (27%), Positives = 104/209 (49%), Gaps = 7/209 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEE-AGKSLQVELNSKYGNK 185 M + K+K V +TG + IG ++V EG HI I D+ E+ A K+ ++ L S + Sbjct: 1 MDIDLKNKSVIVTGGGSNIGRAIVLGFAAEGA-HITIGDVDEQQAQKTAELALLSGAAS- 58 Query: 186 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA---LM---NDSIGIYKKAIEVNVT 347 + ++DVT + + A V + GG+DV++NN LM + +++K I +N Sbjct: 59 AQVVKTDVTQLDQVQAMFKAAVDKFGGVDVLVNNVGWDQLMFFTQTTPDLWQKIIAINYV 118 Query: 348 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527 ++ T A+++M + G+++++SS A+ +Y K+A+ F I + Sbjct: 119 GVLNCTKTALDLMIPRN---AGSIVSISSDASRQGEPREAVYGGVKAAINSFMKTIAKEN 175 Query: 528 HFSKTGVRVLTVCFGATDTALLTDEKLGT 614 + G+R VC G T + TDE G+ Sbjct: 176 --GRYGIRCNVVCPGITIPS-TTDEVGGS 201 >UniRef50_A6W2S3 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Gammaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MWYL1 Length = 256 Score = 71.7 bits (168), Expect = 1e-11 Identities = 65/216 (30%), Positives = 101/216 (46%), Gaps = 9/216 (4%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 KD+ VFI+G ATGIG ++V +G K A +D+ E+AG +L L +K G +F Sbjct: 13 KDRSVFISGGATGIGAAIVEAYAKQGAK-TAFVDLDEKAGTALAKRL-TKDGYDVRFEVC 70 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK---- 371 D+TD + + + A + G I V++NNAA ND + E L+ +K Sbjct: 71 DITDIQDYQSKIRAAAEVFGPITVLLNNAA--NDVRHSLESLTEERFDELVGVNIKHAMF 128 Query: 372 ---AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 A+ M + G GG++IN SV + + P Y +K+A + + R Sbjct: 129 AAQAVAPMMRKLG--GGSIINFGSVGWMMATAGYPTYGTSKAATHGLTRSLAR--DLGGF 184 Query: 543 GVRVLTVCFG--ATDTALLTDEKLGTFDKYLESSCL 644 G+RV T+ G T+ L +K +S CL Sbjct: 185 GIRVNTLVPGWVMTEKQLRMWVDDAAEEKIKQSQCL 220 >UniRef50_A4TBK3 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium gilvum PYR-GCK Length = 543 Score = 71.7 bits (168), Expect = 1e-11 Identities = 58/193 (30%), Positives = 86/193 (44%), Gaps = 4/193 (2%) Frame = +3 Query: 27 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206 D +V +TGAA+GIG + G + I D+ AG L + G Y D Sbjct: 274 DTLVAVTGAASGIGRATALAFAHHGAD-VVISDV-NAAGLDETARLVTSAGVHAYPYTVD 331 Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALIT--STLKAIE 380 V D V E G DVV+NNA + + + A E + I + Sbjct: 332 VADAAAVEAFAEQVCAEHGVPDVVVNNAGVGHAGFFLDTPAEEFDRVLDINFGGVVNGCR 391 Query: 381 IMGKHSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554 GK G GG ++NV+S+A+ T +VM Y +K+AV FS+C+ R E G+ + Sbjct: 392 SFGKRLADRGVGGHIVNVASMASYTPVNVMNAYCTSKAAVFMFSDCL-RAE-LDSFGIGL 449 Query: 555 LTVCFGATDTALL 593 T+C G T ++ Sbjct: 450 TTICPGFISTNIV 462 >UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Bacillus coagulans 36D1|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus coagulans 36D1 Length = 262 Score = 71.7 bits (168), Expect = 1e-11 Identities = 52/199 (26%), Positives = 93/199 (46%), Gaps = 7/199 (3%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197 ++ KV +TG GIG + L G ++ + D+++E G+ ++ G + F Sbjct: 5 DFTGKVAIVTGGGGGIGREAC-LKLAAGGANVVVADLSDELGEETAGKIREN-GGEAIFV 62 Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALI 356 R+DV+ + + + G ID+++NNA L++ ++ K + +NV + Sbjct: 63 RTDVSKSKDVQHYVRTALDTYGKIDILLNNAGWEGKMKPLIDYPEEVFDKLMGINVRGVF 122 Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536 + M K GT++N +SVA L + M Y A+K AV+ + G + Sbjct: 123 LGMKYVLPHMISQ---KSGTIVNTASVAGLVGTPEMVAYGASKHAVIGMTKTAG--IEAA 177 Query: 537 KTGVRVLTVCFGATDTALL 593 +GVRV VC G DT ++ Sbjct: 178 PSGVRVNAVCPGVVDTEMM 196 >UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR; n=9; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 259 Score = 71.7 bits (168), Expect = 1e-11 Identities = 55/205 (26%), Positives = 95/205 (46%), Gaps = 8/205 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 M+ + +V ITG +GIG + V+ + EG K + I DI + G L +L + Sbjct: 1 MTGRIQGRVAVITGGCSGIGLATVQRFVQEGAK-VVIGDIDDARGHQLVEQLGG--ADVA 57 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA--------ALMNDSIGIYKKAIEVNV 344 + DVT +E + G +D+ NNA ++++ + ++K EVN+ Sbjct: 58 TYVHVDVTSKEQVDALFQTAKDAYGSVDIAFNNAGISPPEDDSILDTDLDAWRKVQEVNL 117 Query: 345 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 524 T++ A+ M + G+G + S VA + + Y A+K VL + +G Sbjct: 118 TSVYLCCKAALPHMLEQ--GRGSIINTASFVAVMGAATSQISYSASKGGVLSMTRELG-- 173 Query: 525 EHFSKTGVRVLTVCFGATDTALLTD 599 F++ GVRV +C G +T LL + Sbjct: 174 VQFARQGVRVNALCPGPVNTPLLQE 198 >UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=18; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Arthrobacter sp. (strain FB24) Length = 263 Score = 71.7 bits (168), Expect = 1e-11 Identities = 59/208 (28%), Positives = 97/208 (46%), Gaps = 18/208 (8%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK-FYR 200 K V ITG A+G+G + R L D G + ++D+ G++ ELN+ G T F Sbjct: 4 KGTVALITGGASGLGAATARRLFDAGAS-VVLVDLPSSRGEAFAAELNAASGAGTAVFVP 62 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS----------IGIYKKAIEVN--- 341 +DVT EE + A V G + +V+N A + + + + I++N Sbjct: 63 ADVTSEEQVQAAVAAAVA-LGPLRIVVNCAGIATPGKVLGRDGVLPLDTFSRVIQINLVG 121 Query: 342 ---VTALITSTLKAIEIMGKHSGG-KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 509 V L + + A E + GG + G +IN +SVAA P Y A+K AV + Sbjct: 122 TFNVIRLAAAAMAATEPVSTELGGPERGVIINTASVAAFDGQIGQPAYAASKGAVAAMTL 181 Query: 510 CIGRPEHFSKTGVRVLTVCFGATDTALL 593 I R +++ +RV+T+ G +T ++ Sbjct: 182 PIAR--ELARSLIRVVTIAPGIFETPMM 207 >UniRef50_A7S4C5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 306 Score = 71.7 bits (168), Expect = 1e-11 Identities = 63/222 (28%), Positives = 103/222 (46%), Gaps = 7/222 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 + + V ITGAA+GIG IL +G K + + DI EA K++ E+ G +T ++ Sbjct: 34 RGETVLITGAASGIGRLTALILAKKGCK-LVLWDINLEALKAVAQEIQD-LGAETHYFEC 91 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 365 DV ++ + NAV + G + ++INNA + +N S + +VN A I + Sbjct: 92 DVRKKDEVEKVANAVEDQAGNVTILINNAGVVTGKKFLNCSESDVMRTFQVNSLAHIWTI 151 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH-FSKT 542 + I M + + G +++++SVA Y A+K A + + R H K Sbjct: 152 QRFIPSMMEKNRGH---IVSIASVAGYFGLVGCVDYCASKFAAVGLIEALRREIHGLGKM 208 Query: 543 GVRVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKKGFI 668 G+ T+C T T + KL KY L +LK F+ Sbjct: 209 GIEFTTICPHFTATGMFAGVKL----KYPNLPGLGELKPEFV 246 >UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular organisms|Rep: Oxidoreductase - Halobacterium salinarium (Halobacterium halobium) Length = 260 Score = 71.7 bits (168), Expect = 1e-11 Identities = 58/200 (29%), Positives = 91/200 (45%), Gaps = 6/200 (3%) Frame = +3 Query: 15 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF 194 HE V +TGA++GIGE+ L EG + A+E +L + G+ Sbjct: 16 HELAGDVAIVTGASSGIGEATAEALAAEGAHVVLAARRADELA-ALADRIEDTDGDAL-V 73 Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALI 356 +D+TD++ +++ V E G ID+++NNA +M ++ +EVN+ L+ Sbjct: 74 VPTDITDDDAIDDLVSETVDEYGRIDILVNNAGVMLLEPLERADRSNLRQMVEVNLLGLM 133 Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536 T + IM G V+NVSSVA Y ATK V F++ I + + Sbjct: 134 NLTHAVVPIMQDQDAGH---VVNVSSVAGRQADADSSGYNATKFGVNAFTDAI--RQELT 188 Query: 537 KTGVRVLTVCFGATDTALLT 596 +R + GA DT L T Sbjct: 189 SQDIRTTIIEPGAVDTELST 208 >UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=1; Natronomonas pharaonis DSM 2160|Rep: Probable dehydrogenase/ reductase 4 - Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) Length = 253 Score = 71.7 bits (168), Expect = 1e-11 Identities = 54/194 (27%), Positives = 86/194 (44%), Gaps = 4/194 (2%) Frame = +3 Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200 +++ VFITGA +GIG + + EG +A DI E+ G+ V+ G F+ Sbjct: 3 FENDTVFITGAGSGIGRATALKVAREGAFVVAT-DINEDGGRET-VDAVEDAGGDAAFHE 60 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI---GIYKKAIEVNVTALITSTLK 371 DVTD + F ++ E G +D +INNA + + + + E + + Sbjct: 61 LDVTDADEFKAVVETAADEYG-LDAMINNAGVGHPPAYTEDVTETTFEYVLDVNLRGVWN 119 Query: 372 AIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 + H +G G ++NV S+A+ +Y TK AVL + I + GV Sbjct: 120 GCQAALPHLKSQGEGAIVNVGSLASFLGLPKQAVYSLTKGAVLNLTRAIA--SEAGRDGV 177 Query: 549 RVLTVCFGATDTAL 590 R VC G +T L Sbjct: 178 RANAVCPGFIETPL 191 >UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34; Proteobacteria|Rep: Acetoacetyl-CoA reductase - Acinetobacter sp. (strain RA3849) Length = 248 Score = 71.7 bits (168), Expect = 1e-11 Identities = 50/197 (25%), Positives = 91/197 (46%), Gaps = 6/197 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 + KV +TGA GIG + R L+ G K IA + EE + ++ + +F + Sbjct: 3 EQKVALVTGALGGIGSEICRQLVTAGYKIIATVVPREEDREKQWLQSEGFQDSDVRFVLT 62 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITST 365 D+ + E + + +G +DV++NNA + D S + + I+ N+ L T T Sbjct: 63 DLNNHEAATAAIQEAIAAEGRVDVLVNNAGITRDATFKKMSYEQWSQVIDTNLKTLFTVT 122 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 + K K G ++N+SSV L Y A+K+ ++ F+ + + +++ Sbjct: 123 Q---PVFNKMLEQKSGRIVNISSVNGLKGQFGQANYSASKAGIIGFTKALA--QEGARSN 177 Query: 546 VRVLTVCFGATDTALLT 596 + V V G T T ++T Sbjct: 178 ICVNVVAPGYTATPMVT 194 >UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59; cellular organisms|Rep: Acetoin(diacetyl) reductase - Klebsiella pneumoniae Length = 256 Score = 71.7 bits (168), Expect = 1e-11 Identities = 54/193 (27%), Positives = 88/193 (45%), Gaps = 6/193 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV +TGA GIG+++ L+ +G +AI D + K++ E+N G + + DV Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFA-VAIADYNDATAKAVASEINQA-GGRAMAVKVDV 60 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMN----DSI--GIYKKAIEVNVTALITSTLK 371 +D + + + GG DV++NNA + +SI I K +NV +I Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQA 120 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 A+E K G GG +IN S A + + +Y ++K AV + R + G+ Sbjct: 121 AVEAFKKE--GHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAAR--DLAPLGIT 176 Query: 552 VLTVCFGATDTAL 590 V C G T + Sbjct: 177 VNGYCPGIVKTPM 189 >UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3; Clostridium|Rep: Bile acid 7-dehydroxylase 1/3 - Eubacterium sp. (strain VPI 12708) Length = 249 Score = 71.7 bits (168), Expect = 1e-11 Identities = 52/219 (23%), Positives = 101/219 (46%), Gaps = 7/219 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-YR 200 +DK+ ITG GIG + ++ ++ G K ++I +E + +L Y + + Sbjct: 5 QDKITIITGGTRGIGFAAAKLFIENGAK-VSIFGETQEEVDTALAQLKELYPEEEVLGFA 63 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 362 D+T + + + V Q+ G +DV+INNA + +S+ +K +++NV + Sbjct: 64 PDLTSRDAVMAAVGTVAQKYGRLDVMINNAGITMNSVFSRVSEEDFKNIMDINVNGVFNG 123 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 A + M K G +IN +SV + S Y +K+ V+ ++ +GR + Sbjct: 124 AWSAYQCM---KDAKQGVIINTASVTGIYGSLSGIGYPTSKAGVIGLTHGLGR--EIIRK 178 Query: 543 GVRVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKK 659 +RV+ V G DT + + YL++ + ++ K Sbjct: 179 NIRVVGVAPGVVDTDMTKGLPPEILEDYLKTLPMKRMLK 217 >UniRef50_Q89UC3 Cluster: D-beta-hydroxybutyrate dehydrogenase; n=11; Proteobacteria|Rep: D-beta-hydroxybutyrate dehydrogenase - Bradyrhizobium japonicum Length = 249 Score = 71.3 bits (167), Expect = 2e-11 Identities = 50/193 (25%), Positives = 91/193 (47%), Gaps = 4/193 (2%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 K V +TGAA+G+G + R+ EG ++A+ D E+ S+ E+ + G K ++ Sbjct: 2 KGLTVLVTGAASGMGRATARVFAAEGA-NVAVTDYDEQGAISVAKEIAAS-GGSAKAWKL 59 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIG--IYKKAIEVNVTALITSTLKA 374 DV D +++ V GG+D+V+NNA + + +I Y+ A + ++T+ + Sbjct: 60 DVADGGEIKRVVHDVAAHFGGLDIVVNNAGISVRVAIDDETYEDAWARGIAVMLTAHPRI 119 Query: 375 IEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 I H K ++N++S AL + + Y A K V + + + G+ Sbjct: 120 IRAALPHLRKSKSPRIVNIASTEALGATALHSPYSAAKGGVASLTRSLA--VELGREGIT 177 Query: 552 VLTVCFGATDTAL 590 V +C G TA+ Sbjct: 178 VNCICPGPIRTAI 190 >UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=1; Oceanobacter sp. RED65|Rep: Putative fatty acyl chain reductase - Oceanobacter sp. RED65 Length = 252 Score = 71.3 bits (167), Expect = 2e-11 Identities = 48/194 (24%), Positives = 99/194 (51%), Gaps = 6/194 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K+V ITG + +G + V + + + ++++ L V + G + R ++ Sbjct: 10 KIVLITGGSGDLGRASVLEFGKQKCRVYFTYNSSKDSADEL-VASAEESGFEAFPIRCNI 68 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 371 +D+E ++N +V+++G IDV++NNA + D++ +++ I+ N+ T Sbjct: 69 SDKEQVNALVNDIVEKEGKIDVLVNNAGIYKDNLFTSMTDEEFEQVIQTNLYGTFYCTKS 128 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 +++M ++ + G ++NVSS+A +T S Y A K AV+ FS + + +R Sbjct: 129 VVDVMYRN---RCGAIVNVSSIAGVTNSFGQANYSAAKGAVVSFSRTLA--AELAPKNIR 183 Query: 552 VLTVCFGATDTALL 593 V TV G D++++ Sbjct: 184 VNTVAPGLIDSSMV 197 >UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 286 Score = 71.3 bits (167), Expect = 2e-11 Identities = 48/181 (26%), Positives = 88/181 (48%), Gaps = 6/181 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 + F+TG GIG ++ I L E ++AILDI E + + G + + +DV Sbjct: 10 QAAFVTGGGGGIGRAIA-IRLAEAGANVAILDIIAERAEETATRIRET-GARALTFPADV 67 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLK 371 + + ++ G +D+++NNA + S +K I++N+ +++ +T Sbjct: 68 MESDALRAAIDQAAAAFGRLDILVNNAGGVSARPFLEQSERSMRKHIDINLMSMLVATQA 127 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 A M +GGKGG++INV+S+ A + +Y A K+ + F+ + S G+R Sbjct: 128 AARHMV--AGGKGGSIINVASIEATRAAPNFAVYAACKAGMFSFTRSMAL--ELSGHGIR 183 Query: 552 V 554 V Sbjct: 184 V 184 >UniRef50_A5WHV5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Psychrobacter sp. PRwf-1|Rep: Short-chain dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1 Length = 273 Score = 71.3 bits (167), Expect = 2e-11 Identities = 59/198 (29%), Positives = 96/198 (48%), Gaps = 10/198 (5%) Frame = +3 Query: 42 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKY---GNKTKFYRSDVT 212 +TGAA+GIG ++ LL + + DI EA Q+ N K G + DV Sbjct: 7 VTGAASGIGRALCERLLTDKGNQVCACDINYEA--LTQIYANHKLADAGGSLILRQLDVR 64 Query: 213 DEEHFLGILNAVVQEQGGIDVVINNAALMNDS----IGIYKKA---IEVNVTALITSTLK 371 D + + ++N V+ + IDV+ N A ++ D+ I + ++NV I T Sbjct: 65 DVQQWQEVVNTVIAQWQRIDVMCNIAGVLKDNWIADIALPDDVDLHFDINVKGTIFGTQS 124 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 ++ M ++ G G +INV+S+AAL+ + +Y A+K AV +S G K G+ Sbjct: 125 VVDTM-RNQGS--GHIINVASLAALSPVPGLSLYSASKYAVRAYSLAAGM--ELEKYGIA 179 Query: 552 VLTVCFGATDTALLTDEK 605 V T+C A T +L +K Sbjct: 180 VTTLCPDAVQTPMLDQQK 197 >UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Sphingomonadaceae|Rep: Short-chain dehydrogenase/reductase SDR - Novosphingobium aromaticivorans (strain DSM 12444) Length = 261 Score = 71.3 bits (167), Expect = 2e-11 Identities = 52/201 (25%), Positives = 99/201 (49%), Gaps = 8/201 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 MS + KV +TG + GIG + R+L G + I E+ ++ + E+ +K G K Sbjct: 1 MSQDMTGKVAIVTGGSDGIGLATARLLAARGAT-VVICARREDKLEAARAEI-AKVG-KV 57 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTA 350 + + DV+DE F ++ V G +D+++NNA ++ + + ++K VN A Sbjct: 58 EAVKLDVSDEAAFTALVEDVAARHGRLDMLVNNAMSVHYAPIAKLRLDHWRKDFAVNADA 117 Query: 351 LITSTLKAIEIMG--KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 524 + T A+++M + G + G ++N++S + + M Y A+K+A++ F+ Sbjct: 118 VFVGTKAAMKVMAAQEQRGRQRGAIVNIASTCGIRAAPNMASYSASKAAMVHFTAAAAM- 176 Query: 525 EHFSKTGVRVLTVCFGATDTA 587 + G+RV + G TA Sbjct: 177 -EGAPLGIRVNAIVPGQVMTA 196 >UniRef50_A4ALI9 Cluster: Putative short chain dehydrogenase; n=2; Actinobacteria (class)|Rep: Putative short chain dehydrogenase - marine actinobacterium PHSC20C1 Length = 265 Score = 71.3 bits (167), Expect = 2e-11 Identities = 56/192 (29%), Positives = 90/192 (46%), Gaps = 6/192 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 M+H K++ V ITG +GIG + + G + + + D++ A +S+ E+ G+ Sbjct: 1 MTHPLKNQTVLITGGGSGIGRLLALGAAERGAR-VVVWDLSAAAAESVCEEILGA-GHHA 58 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTA 350 + + DV+D +NA ++ G +DV+INNA L++ S ++ I VN A Sbjct: 59 EAFTVDVSDRN----AVNAAAKKTGQVDVLINNAGIVTGKNLLDASDEAIERTIRVNTLA 114 Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530 L T +G + GTV+ +SS A L Y A+K A L F+ + Sbjct: 115 LFWVTRA---FLGNMIANRRGTVVTISSAAGLVGVAKQTDYSASKFAALGFAESLRVELS 171 Query: 531 FSKTGVRVLTVC 566 TGV L VC Sbjct: 172 KENTGVNSLVVC 183 >UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bacterium HTCC2150|Rep: Dehydrogenase - Rhodobacterales bacterium HTCC2150 Length = 279 Score = 71.3 bits (167), Expect = 2e-11 Identities = 54/199 (27%), Positives = 96/199 (48%), Gaps = 7/199 (3%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDI-AEEAGKSLQVELNSKYGNKTKFYR 200 K+K V +TGAA G+G + L +G ++ + D+ AE+ +S+Q + ++ Sbjct: 23 KNKTVIVTGAAQGLGYACALRFLQDGA-NVVMADVNAEKLAESVQDLI--EFDGAVSSMV 79 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSIGIYKKAIEVNVTALITSTLKA 374 DVT E+ ++ V G +DV+INNA + + D + I + + + Sbjct: 80 CDVTKRENLQALVGLAVSNYGNLDVMINNAGIAKVQDFLEISDDEYDAVMDVNLRGAFIG 139 Query: 375 IEIMGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN--CIGRPEHFSKT 542 +I GK + GKGG +IN+SS+ AL + ++ Y +K + Q +N +G H Sbjct: 140 TQIAGKQMIAQGKGGVIINMSSINALVANPMLSTYAISKGGMNQLTNIAAVGLAPH---- 195 Query: 543 GVRVLTVCFGATDTALLTD 599 +RV + G T ++ D Sbjct: 196 NIRVCGIGPGTILTDMVAD 214 >UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family protein; n=1; Algoriphagus sp. PR1|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family protein - Algoriphagus sp. PR1 Length = 265 Score = 71.3 bits (167), Expect = 2e-11 Identities = 53/210 (25%), Positives = 106/210 (50%), Gaps = 8/210 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV+ +TG+ TGIG+++ + ++ EG K + I + E+ G+ + EL + + K + D+ Sbjct: 6 KVIIVTGSTTGIGKAIAKKVVSEGAK-VIIHGLEEDLGQQVVSELGA---DNAKLHIEDI 61 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITSTLK 371 ++E +++ V+ G +D ++NNAA++ S + +EVN + T Sbjct: 62 SNEGAAQRLVDIAVKTWGKLDSIVNNAAIVAASTLFDTDKAFLNRILEVNTISPFLLTQA 121 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 AI + ++ G V+N+ S+ A + H + Y +K A++ + +G F + GVR Sbjct: 122 AISQLIQNK----GAVLNIGSINAYSGEHNLLAYSISKGALMTMTRNLG-DSLFRENGVR 176 Query: 552 VLTVCFG--ATDTALLTDEKLGTFDKYLES 635 V + G T+ + ++ G D + E+ Sbjct: 177 VNQINPGWVLTENEIARKKEHGLSDTWYEN 206 >UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 253 Score = 71.3 bits (167), Expect = 2e-11 Identities = 54/196 (27%), Positives = 89/196 (45%), Gaps = 5/196 (2%) Frame = +3 Query: 18 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197 ++ KVV ITG ATGIG + +G + + + D+ + A ++ V L + G F Sbjct: 6 DFTGKVVLITGGATGIGRATALAFAQQGAR-VVVGDVDDRAAET--VRLIEESGGTALFV 62 Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 377 R+DVT ++ V GG+ V NNA ++ + G + E + I LK + Sbjct: 63 RTDVTSAADVQQLVRTTVDTYGGLHVAFNNAGILPPT-GPLAEQSEDDFDRTIAVDLKGV 121 Query: 378 EIMGKH-----SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 + K+ + GG++IN +SVA + M Y A K V+ + ++ Sbjct: 122 FLALKYEIEHMAAAGGGSIINTASVAGVIADPGMAPYVAAKHGVVGLTRAAA--IDYAAA 179 Query: 543 GVRVLTVCFGATDTAL 590 GVRV + G DT + Sbjct: 180 GVRVNALAPGLVDTPM 195 >UniRef50_A0Z215 Cluster: Short chain dehydrogenase; n=2; Gammaproteobacteria|Rep: Short chain dehydrogenase - marine gamma proteobacterium HTCC2080 Length = 291 Score = 71.3 bits (167), Expect = 2e-11 Identities = 48/181 (26%), Positives = 85/181 (46%), Gaps = 2/181 (1%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K + ITGAA+G+G ++ + EG + I DI +E G + +LN +Y N F ++ Sbjct: 2 KRILITGAASGLGLALAKKYASEGWS-VCIADIQDEEGIKIAAQLNEEYANDCFFQHLNI 60 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGIYK-KAIEVNVTALITSTLKAIEI 383 T + + ++ + + G+D ++NNA + + I + K + V + +K + Sbjct: 61 TSDTQWQELVALISERWQGLDALVNNAGVGASGDIDTFSIKDFQWTVDINLMGAVKGCHV 120 Query: 384 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 563 G +INV+S+A L M Y +K+ ++ FS G GV+V V Sbjct: 121 CVPLLKESKGLLINVASMAGLLHMGSMSAYNVSKAGMVAFSE--GLLSELDPYGVKVSVV 178 Query: 564 C 566 C Sbjct: 179 C 179 >UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Stappia aggregata IAM 12614|Rep: Short-chain dehydrogenase/reductase SDR - Stappia aggregata IAM 12614 Length = 270 Score = 71.3 bits (167), Expect = 2e-11 Identities = 54/200 (27%), Positives = 95/200 (47%), Gaps = 8/200 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 +V +TGA+ GIGE+ R L G K + + +++ + + E+ ++ G DV Sbjct: 24 QVALVTGASRGIGEAAARSLAKYGAK-VVLAARSDKDIERIAGEIRAE-GQDATAVVCDV 81 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 368 D + + + V GG+D+++NNA ++ I + K I++NV + Sbjct: 82 ADYDDVVKAVQTAVDTYGGLDILVNNAGVIEPIARIEDSDPAEWGKVIDINVKGVYYG-- 139 Query: 369 KAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 + KH KG GTV+N+SS AA++ Y A+K+A L + C + F G Sbjct: 140 --LHAAAKHMLAKGAGTVVNISSGAAVSALEGWSHYCASKAAALSLTRCADK--EFGDKG 195 Query: 546 VRVLTVCFGATDTALLTDEK 605 +R++ + G T + D K Sbjct: 196 LRIVGLSPGTVATQMQVDIK 215 >UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family member 10; n=19; Eumetazoa|Rep: Dehydrogenase/reductase SDR family member 10 - Homo sapiens (Human) Length = 270 Score = 71.3 bits (167), Expect = 2e-11 Identities = 61/195 (31%), Positives = 93/195 (47%), Gaps = 8/195 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KVV +TG GIG +VR ++ G + + I D E G++L+ EL F DV Sbjct: 10 KVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPG-----AVFILCDV 63 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 368 T E+ +++ ++ G +D V+NNA S +++ +E+N+ T T Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 Query: 369 KAIEIMGKHSGGKGGTVINVSS-VAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 A+ + K G VIN+SS V A+ Q+ +P Y ATK AV + + E S G Sbjct: 124 LALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE--SPYG 176 Query: 546 VRVLTVCFGATDTAL 590 VRV + G T L Sbjct: 177 VRVNCISPGNIWTPL 191 >UniRef50_P39071 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; n=31; Bacteria|Rep: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase - Bacillus subtilis Length = 261 Score = 71.3 bits (167), Expect = 2e-11 Identities = 51/188 (27%), Positives = 90/188 (47%), Gaps = 3/188 (1%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K+ FITGAA GIGE+V R L +G HIA +D E + + L ++ + + +DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGA-HIAAVDYNPEKLEKVVSSLKAE-ARHAEAFPADV 66 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI--GIYKKAIEVNVTALITSTLKAIEI 383 D I + +E G ID+++N A ++ + + + E + T A Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 384 MGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560 + K+ + G+++ V S A M Y ++K+A + F+ C+G ++ +R Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGL--ELAEYNIRCNI 184 Query: 561 VCFGATDT 584 V G+T+T Sbjct: 185 VSPGSTET 192 >UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|Rep: Bll5898 protein - Bradyrhizobium japonicum Length = 256 Score = 70.9 bits (166), Expect = 3e-11 Identities = 61/201 (30%), Positives = 92/201 (45%), Gaps = 7/201 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 M +KDKVV +TGA +GIG + R EG I +L+ E S E+ ++ G Sbjct: 1 MLSRFKDKVVIVTGAGSGIGAAAARRFHGEGA--IVVLNGRRE---SKLAEVGAELGTDR 55 Query: 189 KFYR-SDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVT 347 R +DVT ++ V+ G ID+++NNA + I ++ VNV Sbjct: 56 CMIRPADVTIAADVESLVADAVRRFGRIDILVNNAGTGALIDFLGSPIQQWRDLFAVNVD 115 Query: 348 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527 ++ T A+ H GG+++NVSS++ L + Y ATK AV + + Sbjct: 116 GVLYMTRAAL----PHLIESGGSIVNVSSLSGLGGDRGLSFYNATKGAVSNLTRSLAL-- 169 Query: 528 HFSKTGVRVLTVCFGATDTAL 590 F GVR+ VC T T L Sbjct: 170 EFGPRGVRINAVCPSLTLTHL 190 >UniRef50_A6VY27 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MWYL1 Length = 252 Score = 70.9 bits (166), Expect = 3e-11 Identities = 64/226 (28%), Positives = 106/226 (46%), Gaps = 9/226 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 ++++ +K +TG A+GIG + V +L G +AI D+ EEA + + + SKY K Sbjct: 2 INYQLDNKKAMVTGGASGIGLACVELLAYSGAD-VAIWDLHEEALEKAKQSI-SKYNVKC 59 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI--GIYK-----KAIEVNVT 347 + DV+D E + +++ G +D+ +NNA + + G Y K I+VN Sbjct: 60 ITIKVDVSDPESVKAAMAETLKQLGSLDIAVNNAGIGGPACKSGDYTTEDWLKVIDVNFN 119 Query: 348 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527 + +AI M K+ G++IN++S+ P Y + K V+ S E Sbjct: 120 GVFYCQREAIAAMRKNG---SGSIINMASILGQVAFPSSPAYVSAKHGVVGMSKA-SAVE 175 Query: 528 HFSKTGVRVLTVCFGATDTALLTDEKLG--TFDKYLESSCLDQLKK 659 H ++ +RV V G T L+ DE L T D + L +L K Sbjct: 176 H-AEDNIRVNAVGPGFIHTPLV-DEHLDAETLDMLAQKHALKRLGK 219 >UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacteria|Rep: Cyclopentanol dehydrogenase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 355 Score = 70.9 bits (166), Expect = 3e-11 Identities = 57/194 (29%), Positives = 92/194 (47%), Gaps = 6/194 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV ITG A G GE+ R+ G H+ I D+ EE G+ L EL G + F DV Sbjct: 102 KVALITGGARGQGEAEARLFAQHGA-HVYICDVLEEEGEKLAAELRGS-GLQADFRFLDV 159 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL-----MNDSIG-IYKKAIEVNVTALITSTLK 371 TD E + + + G +DV+INNA + + D+ + + + VN + ++ Sbjct: 160 TDAEQWSRTVAHIDAGAGRLDVLINNAGINVRHQLTDTTSEEWDRIVAVNTKGQMLG-MQ 218 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 A + K SG G++IN+ S A + H + Y A+K AV + + +G+R Sbjct: 219 ACAPLMKRSG--NGSIINIGSTAGI-MGHPVAAYSASKWAVRGLTKAAAM--ELASSGIR 273 Query: 552 VLTVCFGATDTALL 593 V + G +T ++ Sbjct: 274 VNAMHPGVVETPMV 287 >UniRef50_A0PSR4 Cluster: Short-chain dehydrogenase; n=1; Mycobacterium ulcerans Agy99|Rep: Short-chain dehydrogenase - Mycobacterium ulcerans (strain Agy99) Length = 282 Score = 70.9 bits (166), Expect = 3e-11 Identities = 55/191 (28%), Positives = 90/191 (47%), Gaps = 4/191 (2%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 +VV ITGA +GIG + + G +A+ DI + A + +G+ R DV Sbjct: 16 RVVAITGAGSGIGRELALLCAQRGAD-LALCDINDTAVADT-AQTARGFGHDVITRRVDV 73 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITSTLKAIE- 380 +D E +A + GG+D+++NNA L+ + +K + V+ + + E Sbjct: 74 SDPEQMTAFADATLGHFGGVDLLVNNAGVGLIGGFLDTSRKDWDWLVSINVMGVVHGCEA 133 Query: 381 -IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557 + G+GG V+N+SS A L + + Y ATK AVL S + R E + V Sbjct: 134 FLPAMIESGRGGHVVNLSSAAGLLANPALSAYSATKFAVLGLSEAL-RIE-LEPHRIGVT 191 Query: 558 TVCFGATDTAL 590 +C G +TA+ Sbjct: 192 AICPGVINTAI 202 >UniRef50_Q6NNV7 Cluster: RH03309p; n=4; melanogaster subgroup|Rep: RH03309p - Drosophila melanogaster (Fruit fly) Length = 247 Score = 70.9 bits (166), Expect = 3e-11 Identities = 52/204 (25%), Positives = 99/204 (48%), Gaps = 13/204 (6%) Frame = +3 Query: 21 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200 W + V +TGA++GIG ++ R L+ GV +A+ + + L+ EL ++ + + Sbjct: 4 WHNCVAVVTGASSGIGAAITRKLISAGVMVVALARRMDRL-EQLREELPQDRRSRLRIMQ 62 Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITS 362 DV+D + +AV + G +D++INNA L+ S+ ++ ++ NV ++ Sbjct: 63 CDVSDVSSVNAVFDAVQGDLGNVDILINNAGKLSGGQLLTMSVDTVQQMLQTNVMGVVYC 122 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMP-------IYFATKSAVLQFSNCIGR 521 T +A E M + G V+ ++S+ + +P +Y ATK A+ + + Sbjct: 123 TQRAFESMRQRQ--SKGHVVLINSIVGHYIFNPLPGSQQELNMYPATKHAITALTELFRQ 180 Query: 522 PEHFSKTGVRVLTVCFGATDTALL 593 KT V+V ++ G DT L+ Sbjct: 181 EMRDFKTKVKVTSISPGLVDTELV 204 >UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=26; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Chlamydia pneumoniae (Chlamydophila pneumoniae) Length = 248 Score = 70.9 bits (166), Expect = 3e-11 Identities = 52/197 (26%), Positives = 95/197 (48%), Gaps = 7/197 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K V +TG + GIG +V++ L+ G + I + EE G+++ +E + G + F R DV Sbjct: 8 KKVIVTGGSRGIGLGIVKLFLENGAD-VEIWGLNEERGQAV-IESLTGLGGEVSFARVDV 65 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 371 + + + + ID+++NNA + D++ + ++ I N+T+L + Sbjct: 66 SHNGGVKDCVQKFLDKHNKIDILVNNAGITRDNLLMRMSEDDWQSVISTNLTSLYYTCSS 125 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 I M K + G++INV+S+ A S Y A K+ ++ F+ + + V Sbjct: 126 VIRHMIK---ARSGSIINVASIVAKIGSAGQTNYAAAKAGIIAFTKSLAKEVAARNIRVN 182 Query: 552 VLTVCFGATD-TALLTD 599 L F TD T++L D Sbjct: 183 CLAPGFIETDMTSVLND 199 >UniRef50_Q62E12 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=25; Proteobacteria|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Burkholderia mallei (Pseudomonas mallei) Length = 265 Score = 70.5 bits (165), Expect = 3e-11 Identities = 48/170 (28%), Positives = 88/170 (51%), Gaps = 8/170 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG-KSLQVELNSKYGNKTKFYR-S 203 K FITGAA G+G ++ R + ++G + + + DI + A ++ ELN G + + Sbjct: 14 KRAFITGAAGGLGRAIARRMAEQGAQ-VFLTDIVDAAVLEAFAAELNDTAGERIAWAAVQ 72 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN-DSIG-----IYKKAIEVNVTALITST 365 DV DE + L+ GG+ V+++NA + + +IG +++ + +NV +++ T Sbjct: 73 DVADEAQWASRLSQAADAMGGLSVLVHNAGVGSFGAIGQIARDEWRRVMAINVESIVLGT 132 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 515 A+ + G +++N+SSVAA Q Y A+K+AV + I Sbjct: 133 KHALPYL---EAGAPASIVNISSVAAFKQEPDYTAYNASKAAVASLTKSI 179 >UniRef50_Q2S7V4 Cluster: Short-chain alcohol dehydrogenase-like protein; n=1; Hahella chejuensis KCTC 2396|Rep: Short-chain alcohol dehydrogenase-like protein - Hahella chejuensis (strain KCTC 2396) Length = 288 Score = 70.5 bits (165), Expect = 3e-11 Identities = 53/198 (26%), Positives = 94/198 (47%), Gaps = 6/198 (3%) Frame = +3 Query: 15 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF 194 H + +K V ITGAA+G+G + R L G + +A D+ +E G ++ L N+ + Sbjct: 2 HRFPEKRVAITGAASGLGLATARHFLSRGWR-VAFADVQDETGSAIVASLGLP-ENRAFY 59 Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIG-----IYKKAIEVNVTALI 356 DVT +V+ GG+D++INNA + + IG ++ I++++ ++ Sbjct: 60 QHVDVTKVRDIQAWRRKIVETWGGLDILINNAGVAAHGGIGEAPLEDWEWVIDIDLMGVV 119 Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536 + + + + G ++N++S+A L + M Y A K+ V+ S + S Sbjct: 120 RGCKEFAPLFKRQ---RSGQIVNIASMAGLVHAPEMGSYNAAKAGVVALSETL--VGELS 174 Query: 537 KTGVRVLTVCFGATDTAL 590 GV V VC G T L Sbjct: 175 PFGVGVNVVCPGFFSTGL 192 >UniRef50_Q3EU48 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Bacillus thuringiensis serovar israelensis ATCC 35646|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Bacillus thuringiensis serovar israelensis ATCC 35646 Length = 252 Score = 70.5 bits (165), Expect = 3e-11 Identities = 47/201 (23%), Positives = 96/201 (47%), Gaps = 6/201 (2%) Frame = +3 Query: 24 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203 ++K + +TG GIG ++V L EG A ++++ ++ EL S Y ++ Y Sbjct: 11 ENKRIIVTGGCKGIGRAIVEKYLQEGAVVAATYYKSKDSSDQMKSELES-YSDRLAIYNM 69 Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITST 365 DV+D E ++ + + GID+++NN+ + DS+ + K I+ N+ + Sbjct: 70 DVSDAEQVNKVMEQIQDDLKGIDILVNNSGITQDSLLYSMKNSDWDKVIKTNLYGPFYTC 129 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 + M K K G++IN++SV+ + Y A+K ++ + + + + Sbjct: 130 KSVLLNMIKQ---KYGSIINIASVSGIVGIPGQSNYCASKFGLIGLTKSLAK--ELASKN 184 Query: 546 VRVLTVCFGATDTALLTDEKL 608 +RV + G DT ++ + K+ Sbjct: 185 IRVNAIAPGYVDTEMIDNVKI 205 >UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caulobacter sp. K31|Rep: Short-chain dehydrogenase/reductase SDR - Caulobacter sp. K31 Length = 254 Score = 70.5 bits (165), Expect = 3e-11 Identities = 56/194 (28%), Positives = 98/194 (50%), Gaps = 7/194 (3%) Frame = +3 Query: 3 LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN 182 + ++ K KV ITGAA G+GE++ R + G + I D+ E G+++ ++ ++ G Sbjct: 1 MSVNDSLKGKVAIITGAAQGLGEAIAREFVARGAA-VIITDVQREEGEAVAADILAQ-GG 58 Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNV 344 K F DV D E + ++ + G +DV++NNA L+ + I ++ + VNV Sbjct: 59 KALFIAHDVGDAEAWDVVVAKALDTFGKVDVLVNNAGLIQFAPLEEMPIEMFDRVTRVNV 118 Query: 345 TALITSTLKAIEIMGKHSGGKGGTVINVSSV-AALTQSHVMPIYFATKSAVLQFSNCIGR 521 KAI K +G GG +IN+SS+ + Q+ + Y +K AV + + Sbjct: 119 RGPWLG-CKAILPALKAAG--GGAIINMSSMNGMIAQNPGLSAYATSKGAVRMLTKAVA- 174 Query: 522 PEHFSKTGVRVLTV 563 + + + GVRV +V Sbjct: 175 -QDYVQYGVRVNSV 187 >UniRef50_A4T9G9 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Mycobacterium gilvum PYR-GCK|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium gilvum PYR-GCK Length = 260 Score = 70.5 bits (165), Expect = 3e-11 Identities = 55/199 (27%), Positives = 98/199 (49%), Gaps = 9/199 (4%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K V ITGAA+GIG + ++++ EG + + I D+ +A + ++ G ++V Sbjct: 9 KRVVITGAASGIGRAAAQLMIGEGAR-VLIADLDADAAAAAASDI----GGNAIGVAANV 63 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA---------LMNDSIGIYKKAIEVNVTALITS 362 D++ +++ V E GGIDV+ N+ L+ + + +A+ +N + + + Sbjct: 64 LDDKSVAAMIDRAVTEFGGIDVLCNHVGGSNPHKDLDLLRLDLDEWDRAMALNARSTVVA 123 Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 + A+ M GG ++IN SVA LT + Y A+K+AV++ + I + + Sbjct: 124 SRLALPHMIAEGGG---SIINTVSVAGLTGDTLQCAYGASKAAVIRLTQYIA--TQYGRK 178 Query: 543 GVRVLTVCFGATDTALLTD 599 GVR V GA T L D Sbjct: 179 GVRCNAVAPGAVMTPALAD 197 >UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=3; Proteobacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Erythrobacter sp. NAP1 Length = 267 Score = 70.5 bits (165), Expect = 3e-11 Identities = 53/182 (29%), Positives = 90/182 (49%), Gaps = 7/182 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 K V ITG++ GIGE + R EG + AE+ K L++ ++T DV Sbjct: 10 KTVIITGSSAGIGEGIARRFHAEGANVVINARNAEKCAKVADT-LDA---DRTLTCPGDV 65 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-------KAIEVNVTALITSTL 368 + + I+ V+ GG+D ++NNA + S+ ++K + I++NV +I Sbjct: 66 SSSDFANEIVAKTVERFGGLDCLVNNAGVGGSSM-LHKTDDEEIDRIIDINVKGVIYLCR 124 Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 AI + K GG++IN+SSV+ + ++PIY A+K A+ + G + G+ Sbjct: 125 AAIPHLRKSEAVGGGSIINISSVSGIGGDSMLPIYNASKGAMTNLTR--GLAQQIGGMGI 182 Query: 549 RV 554 RV Sbjct: 183 RV 184 >UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family protein; n=3; Bacteroidetes|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family protein - Polaribacter dokdonensis MED152 Length = 257 Score = 70.5 bits (165), Expect = 3e-11 Identities = 62/216 (28%), Positives = 109/216 (50%), Gaps = 13/216 (6%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV ITG++ GIG+++ + L ++G + + I +EA + E + G T + Sbjct: 12 KVAVITGSSKGIGKAIAKGLAEQGAQ-VVISSRNQEACDEVAKEFKEQ-GLDTIGIACHI 69 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG--------IYKKAIEVNVTALITST 365 E+ +++ ++ G ID+++NNAA+ N G I+ K ++VNV A + Sbjct: 70 GKEDQRKNLVDKTIESFGRIDILVNNAAI-NPVFGPIEEVSPEIFDKIMDVNVKA--PWS 126 Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545 L + ++ K G++IN++SV ALT + IY +K+A+L + + + + K G Sbjct: 127 LSNL-VLPHFQTNKNGSIINIASVEALTPGLGLGIYSTSKAAILMLTK--NQAKEWGKYG 183 Query: 546 VRVLTVCFGATDT----ALLTDEK-LGTFDKYLESS 638 V+ +C G T AL +EK L +K L SS Sbjct: 184 VKANAICPGLIKTKFSAALWQNEKILSKVEKALPSS 219 >UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=6; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Paracoccus denitrificans (strain Pd 1222) Length = 253 Score = 70.5 bits (165), Expect = 3e-11 Identities = 52/195 (26%), Positives = 91/195 (46%), Gaps = 7/195 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 M KDKVV ITGA GIG + ++ ++EG + + + D +A + + EL G Sbjct: 1 MDMHLKDKVVLITGAGAGIGAATAKLFIEEGAR-VVVADYLGDAAEQVAAEL----GENA 55 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 350 + + DV+ E +++ V E GG+DV++NNA + ++ I+VN+T Sbjct: 56 RAFTVDVSKAEACKAMVDFTVAEFGGLDVLVNNAGRGSLGTVETQDENDWRSIIDVNLTG 115 Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQS-HVMPIYFATKSAVLQFSNCIGRPE 527 + + A+ + K GG ++N +S A+ + Y A K V + + Sbjct: 116 VYLCSKYAVPELRKRG---GGAIVNTASNIAMAMAIRDRAAYVAAKGGVASLTRAMAL-- 170 Query: 528 HFSKTGVRVLTVCFG 572 F+ +RV +V G Sbjct: 171 DFAADNIRVNSVAPG 185 >UniRef50_Q2FSZ0 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Methanospirillum hungatei JF-1|Rep: Short-chain dehydrogenase/reductase SDR - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 274 Score = 70.5 bits (165), Expect = 3e-11 Identities = 57/200 (28%), Positives = 98/200 (49%), Gaps = 6/200 (3%) Frame = +3 Query: 9 MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188 MS ++ KV +TG +GIG +V LL G I E K+ + + Y N T Sbjct: 1 MSDVFEGKVAIVTGGTSGIGYAVSEELLKRGATVWVIGSRQESVDKARKSF--AAYKN-T 57 Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MND-----SIGIYKKAIEVNVTA 350 +F DVT + G+++A V++ G +D + NNA + M ++ ++++AI++N+ Sbjct: 58 RFLAVDVTVADQVKGMIDACVEKDGRLDYLFNNAGIGMTHPSQYLTLEMWQQAIDLNLWG 117 Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530 ++ A+ +M K G ++N SS+A + Y ATK AV + + R E Sbjct: 118 VVYGVHFALPVM---LAQKSGHIVNTSSIAGIVPLPSQAAYCATKHAVTALTESL-RYEF 173 Query: 531 FSKTGVRVLTVCFGATDTAL 590 F + G+ T+C TA+ Sbjct: 174 FEE-GIAFTTICPSNVATAI 192 >UniRef50_Q48I17 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Pseudomonas syringae pv. phaseolicola 1448A|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) Length = 282 Score = 70.1 bits (164), Expect = 4e-11 Identities = 59/198 (29%), Positives = 101/198 (51%), Gaps = 6/198 (3%) Frame = +3 Query: 33 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVT 212 VV ITGAA GIG+++ L+ G++ I + DI E K L+V L G Y D+T Sbjct: 4 VVLITGAAGGIGQAICAQLIRRGMQLI-LADIDE---KQLRV-LAESLGEDAFPYVVDLT 58 Query: 213 DEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTLKA 374 ++E G++ + E G +DV+INNAA+ S+ + + +N+ A + T A Sbjct: 59 NQESLAGLMTYIESEFGRLDVLINNAAIAVVEAFDTRSVESISRELNINLVAPLILTRLA 118 Query: 375 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554 I ++ + + + VI+ S+ + + PIY A+K + IG ++ G++V Sbjct: 119 IPLLKRSNDAR---VISTVSLGGVFPTPESPIYCASKFGLRGAMLSIGL--DLAEKGIKV 173 Query: 555 LTVCFGATDTALLTDEKL 608 ++ ATDT +L E + Sbjct: 174 GSILPTATDTQMLRKEAI 191 >UniRef50_Q02AD5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR - Solibacter usitatus (strain Ellin6076) Length = 261 Score = 70.1 bits (164), Expect = 4e-11 Identities = 58/205 (28%), Positives = 98/205 (47%), Gaps = 13/205 (6%) Frame = +3 Query: 33 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVT 212 + ITGA++GIG + R+ +G I + + + L EL + + K + +D+ Sbjct: 5 MALITGASSGIGAELARLCAADGYGLILVARRTDRL-EQLGAELAAAHNVKFRTIAADLA 63 Query: 213 DEEHFLGILNAVVQEQGG--IDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 368 + + A+ ++ G ID++INNA + I+VN+TAL T Sbjct: 64 EPD----AATAIYRQTSGDTIDILINNAGFGLRGRYDQTEWNAEARLIQVNITALAQLTK 119 Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548 ++ M + G+ ++NV S AA +M +Y+A+K+ V+ FS + + F TGV Sbjct: 120 SYVKDMVRRGSGR---ILNVGSTAAFVPGPLMAMYYASKAFVVSFSEALAK--EFEGTGV 174 Query: 549 RVLTVCFGATDT-----ALLTDEKL 608 V +C G T T A +TD KL Sbjct: 175 TVTVLCPGPTRTEFDAAAGITDSKL 199 >UniRef50_A5V545 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Sphingomonas wittichii RW1|Rep: Short-chain dehydrogenase/reductase SDR - Sphingomonas wittichii RW1 Length = 264 Score = 70.1 bits (164), Expect = 4e-11 Identities = 54/194 (27%), Positives = 94/194 (48%), Gaps = 6/194 (3%) Frame = +3 Query: 30 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209 KV ITG TGIG ++ R+ +G + ++A EA + VE G D+ Sbjct: 5 KVAIITGGGTGIGAAIARLFARKGAHVVITSELAAEAMAPV-VEAIRADGGSASAMSCDI 63 Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGIYKKAIE----VNVTALITSTLK 371 D ++ V ++ G ID++I +A + + + I+ VNV I+ Sbjct: 64 MDRAAIAALVEGVERDHGRIDILIQSAGVCFAGPIETMEPRKIDLTFGVNVIGAISMIQA 123 Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551 A+ M K +GG G ++N+SS AA+ + M +Y A+K+A+ F+ + PE +T +R Sbjct: 124 ALPAM-KRAGG--GAIVNISSGAAVLGVNEMAVYAASKAAIAHFTRTLA-PE-LRRTNIR 178 Query: 552 VLTVCFGATDTALL 593 + + G+ T +L Sbjct: 179 INAIGPGSVRTQML 192 >UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Polaromonas naphthalenivorans (strain CJ2) Length = 286 Score = 70.1 bits (164), Expect = 4e-11 Identities = 57/207 (27%), Positives = 102/207 (49%), Gaps = 11/207 (5%) Frame = +3 Query: 33 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVT 212 V +TGAA GIG + + L +G++ +A+LD+ +A ++ EL S + DVT Sbjct: 21 VAIVTGAADGIGWATAQRLAADGLR-VALLDLRADAAQARAAELGSIHLG----LGCDVT 75 Query: 213 DEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNV--TALITST 365 EE + AV++ G ID ++NNA + S+ + + + V++ T L++ Sbjct: 76 SEESVEAAVAAVLERFGRIDALVNNAGIGDQTGPTTEQSVQAFDRVLAVHLRGTFLMSRA 135 Query: 366 LKAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542 + + G+G G ++N+ S+A+ T Y A K+ VL + + +++ Sbjct: 136 VARHMLQAAPVPGRGRGAIVNLGSIASSTGLPARNAYSAGKAGVLGMTRAMA--SEWARA 193 Query: 543 GVRVLTVCFGATDTALLTD-EKLGTFD 620 G+RV V G TAL+ + E+ G D Sbjct: 194 GIRVNAVAPGYVRTALVAELERKGAID 220 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 658,888,275 Number of Sequences: 1657284 Number of extensions: 13125401 Number of successful extensions: 46075 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 41735 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 43502 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 51652897375 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
- SilkBase 1999-2023 -