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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= maV30125
         (671 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q1G151 Cluster: Putative alcohol dehydrogenase; n=1; Bo...   175   1e-42
UniRef50_Q6RUR3 Cluster: Putative alcohol dehydrogenase; n=2; Ne...   157   2e-37
UniRef50_Q6NYE8 Cluster: Zgc:56585 protein; n=5; Clupeocephala|R...   153   3e-36
UniRef50_UPI0000DB7440 Cluster: PREDICTED: similar to 15-hydroxy...   149   8e-35
UniRef50_UPI00015B5316 Cluster: PREDICTED: similar to putative a...   142   9e-33
UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative a...   142   9e-33
UniRef50_UPI00015B4C63 Cluster: PREDICTED: similar to putative a...   139   5e-32
UniRef50_UPI0000513348 Cluster: PREDICTED: similar to 15-hydroxy...   139   6e-32
UniRef50_UPI00015B573D Cluster: PREDICTED: similar to putative a...   136   3e-31
UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative a...   132   1e-29
UniRef50_UPI00015B42E2 Cluster: PREDICTED: similar to putative a...   131   1e-29
UniRef50_UPI000051334A Cluster: PREDICTED: similar to 15-hydroxy...   128   1e-28
UniRef50_UPI00015B5A58 Cluster: PREDICTED: similar to putative a...   127   3e-28
UniRef50_UPI0000D57364 Cluster: PREDICTED: similar to 15-hydroxy...   126   5e-28
UniRef50_UPI00015B5FC8 Cluster: PREDICTED: similar to putative a...   125   9e-28
UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|R...   125   1e-27
UniRef50_Q1HPX6 Cluster: Alcohol dehydrogenase; n=1; Bombyx mori...   124   2e-27
UniRef50_P15428 Cluster: 15-hydroxyprostaglandin dehydrogenase [...   122   1e-26
UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative a...   121   1e-26
UniRef50_UPI0000E47587 Cluster: PREDICTED: similar to 15-hydroxy...   121   1e-26
UniRef50_Q7PY55 Cluster: ENSANGP00000013280; n=4; Endopterygota|...   119   6e-26
UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to hydroxypro...   119   7e-26
UniRef50_UPI0000D57365 Cluster: PREDICTED: similar to CG4899-PA,...   114   2e-24
UniRef50_UPI00015B572C Cluster: PREDICTED: similar to putative a...   108   1e-22
UniRef50_Q9I7R3 Cluster: CG18814-PA; n=3; Sophophora|Rep: CG1881...   103   3e-21
UniRef50_UPI0000D5767E Cluster: PREDICTED: similar to 15-hydroxy...   102   7e-21
UniRef50_Q5P8S6 Cluster: Putative dehydrogenase; n=4; Proteobact...    99   1e-19
UniRef50_A6YPS8 Cluster: Oxidoreductase; n=1; Triatoma infestans...    96   8e-19
UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR...    95   1e-18
UniRef50_Q9NAR7 Cluster: Alcohol dehydrogenase; n=23; Schizophor...    95   1e-18
UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1; ...    93   4e-18
UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella ve...    93   4e-18
UniRef50_Q9ABI1 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    93   7e-18
UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase fam...    91   2e-17
UniRef50_Q6C6W8 Cluster: Similar to tr|Q9WYD3 Thermotoga maritim...    91   2e-17
UniRef50_Q5TWK5 Cluster: ENSANGP00000025423; n=1; Anopheles gamb...    89   7e-17
UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR...    89   9e-17
UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: O...    89   1e-16
UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain dehydrogena...    88   2e-16
UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    88   2e-16
UniRef50_Q89M15 Cluster: Dehydrogenase; n=3; Proteobacteria|Rep:...    87   3e-16
UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR...    87   3e-16
UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reducta...    87   4e-16
UniRef50_Q2W431 Cluster: Dehydrogenase with different specificit...    87   4e-16
UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillu...    87   5e-16
UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    86   6e-16
UniRef50_Q6XPZ7 Cluster: Short-chain dehydrogenase/reductase; n=...    86   8e-16
UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase b...    85   1e-15
UniRef50_P91615 Cluster: Alcohol dehydrogenase-related 31 kDa pr...    85   1e-15
UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR...    85   2e-15
UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR...    85   2e-15
UniRef50_Q89KQ8 Cluster: Blr4846 protein; n=2; Proteobacteria|Re...    83   4e-15
UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR...    83   4e-15
UniRef50_P00334 Cluster: Alcohol dehydrogenase; n=485; Drosophil...    83   4e-15
UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    83   8e-15
UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1; Psychro...    83   8e-15
UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR...    83   8e-15
UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR...    83   8e-15
UniRef50_P54398 Cluster: Fat body protein 2; n=6; Schizophora|Re...    83   8e-15
UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain dehydrogena...    82   1e-14
UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyc...    82   1e-14
UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3; Bacill...    82   1e-14
UniRef50_Q6UWP2 Cluster: Dehydrogenase/reductase SDR family memb...    82   1e-14
UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR...    81   2e-14
UniRef50_Q28GY1 Cluster: Novel protein containing short chain de...    81   2e-14
UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogena...    81   2e-14
UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR...    81   3e-14
UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;...    81   3e-14
UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    80   4e-14
UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR...    80   4e-14
UniRef50_Q8YQR6 Cluster: All3753 protein; n=6; Bacteria|Rep: All...    80   6e-14
UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2; Actinom...    80   6e-14
UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR...    80   6e-14
UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;...    80   6e-14
UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4; Brucel...    79   7e-14
UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep...    79   7e-14
UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacte...    79   7e-14
UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    79   1e-13
UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductas...    79   1e-13
UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR...    79   1e-13
UniRef50_A1IFS9 Cluster: Short chain dehydrogenase family protei...    79   1e-13
UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    79   1e-13
UniRef50_P19871 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=...    79   1e-13
UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular ...    79   1e-13
UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SD...    79   1e-13
UniRef50_Q399N8 Cluster: Short-chain dehydrogenase/reductase SDR...    79   1e-13
UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...    79   1e-13
UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR...    79   1e-13
UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammapr...    79   1e-13
UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20; ...    78   2e-13
UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR...    78   2e-13
UniRef50_A1UMZ0 Cluster: Short-chain dehydrogenase/reductase SDR...    78   2e-13
UniRef50_Q22CU9 Cluster: Oxidoreductase, short chain dehydrogena...    78   2e-13
UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    78   2e-13
UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogena...    78   2e-13
UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR...    78   2e-13
UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Li...    77   3e-13
UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe...    77   3e-13
UniRef50_Q82FK0 Cluster: Putative dehydrogenase; n=2; Streptomyc...    77   3e-13
UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2; Bacteri...    77   3e-13
UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii K...    77   3e-13
UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Sho...    77   3e-13
UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR...    77   3e-13
UniRef50_A0HI81 Cluster: Short-chain dehydrogenase/reductase SDR...    77   3e-13
UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019;...    77   3e-13
UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    77   4e-13
UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR...    77   4e-13
UniRef50_Q15Q07 Cluster: Short-chain dehydrogenase/reductase SDR...    77   4e-13
UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR...    77   4e-13
UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=...    77   4e-13
UniRef50_Q71R50 Cluster: Dehydrogenase/reductase SDR family memb...    77   4e-13
UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n...    77   5e-13
UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase...    77   5e-13
UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8;...    77   5e-13
UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR...    77   5e-13
UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Re...    77   5e-13
UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain dehydrogena...    76   7e-13
UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR...    76   7e-13
UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR...    76   7e-13
UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR...    76   7e-13
UniRef50_Q97EW4 Cluster: Predicted short-chain dehydrogenase; n=...    76   9e-13
UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    76   9e-13
UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain dehydrogena...    76   9e-13
UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reducta...    76   9e-13
UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR...    76   9e-13
UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR...    76   9e-13
UniRef50_O86553 Cluster: Putative dehydrogenase; n=1; Streptomyc...    76   9e-13
UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase, puta...    76   9e-13
UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-car...    75   1e-12
UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4; Legion...    75   1e-12
UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=...    75   1e-12
UniRef50_A0X2J5 Cluster: Short-chain dehydrogenase/reductase SDR...    75   1e-12
UniRef50_Q9FX95 Cluster: ARP protein; n=8; Magnoliophyta|Rep: AR...    75   1e-12
UniRef50_UPI0000E465C5 Cluster: PREDICTED: similar to MGC80593 p...    75   2e-12
UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -...    75   2e-12
UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    75   2e-12
UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii K...    75   2e-12
UniRef50_Q2JG54 Cluster: Short-chain dehydrogenase/reductase SDR...    75   2e-12
UniRef50_Q1IPJ3 Cluster: Short-chain dehydrogenase/reductase SDR...    75   2e-12
UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...    75   2e-12
UniRef50_A6UZF9 Cluster: Oxidoreductase, short chain dehydrogena...    75   2e-12
UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protei...    75   2e-12
UniRef50_A1BFL6 Cluster: Short-chain dehydrogenase/reductase SDR...    75   2e-12
UniRef50_A0VFC2 Cluster: Short-chain dehydrogenase/reductase SDR...    75   2e-12
UniRef50_A0LZZ5 Cluster: Short-chain dehydrogenase/reductase fam...    75   2e-12
UniRef50_Q2UEK6 Cluster: Dehydrogenases with different specifici...    75   2e-12
UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    75   2e-12
UniRef50_P66778 Cluster: Probable oxidoreductase ephD; n=16; Myc...    75   2e-12
UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    75   2e-12
UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1...    75   2e-12
UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR...    75   2e-12
UniRef50_Q0GL61 Cluster: Short-chain dehydrogenase; n=3; Lactoba...    75   2e-12
UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR...    75   2e-12
UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x;...    75   2e-12
UniRef50_A5BP77 Cluster: Putative uncharacterized protein; n=1; ...    75   2e-12
UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;...    75   2e-12
UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR...    74   3e-12
UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR...    74   3e-12
UniRef50_A6CTS3 Cluster: Putative uncharacterized protein; n=1; ...    74   3e-12
UniRef50_A4XF64 Cluster: Short-chain dehydrogenase/reductase SDR...    74   3e-12
UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1; ...    74   3e-12
UniRef50_Q2U0U8 Cluster: Dehydrogenases with different specifici...    74   3e-12
UniRef50_Q5UYC2 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    74   3e-12
UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    74   3e-12
UniRef50_Q7M9W0 Cluster: 3-OXOACYL-REDUCTASE; n=24; Epsilonprote...    74   4e-12
UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chai...    74   4e-12
UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacill...    74   4e-12
UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    74   4e-12
UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like ...    74   4e-12
UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR...    74   4e-12
UniRef50_A2U319 Cluster: Short-chain dehydrogenase/reductase SDR...    74   4e-12
UniRef50_UPI00015B4F48 Cluster: PREDICTED: similar to ENSANGP000...    73   5e-12
UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap...    73   5e-12
UniRef50_Q3IVD0 Cluster: Short-chain alcohol dehydrogenases; n=2...    73   5e-12
UniRef50_Q3VZL7 Cluster: Short-chain dehydrogenase/reductase SDR...    73   5e-12
UniRef50_Q03X86 Cluster: Putative uncharacterized protein; n=1; ...    73   5e-12
UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5; Proteob...    73   5e-12
UniRef50_Q8FA17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    73   6e-12
UniRef50_Q0VL04 Cluster: Oxidoreductase, putative; n=1; Alcanivo...    73   6e-12
UniRef50_Q0S5L2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    73   6e-12
UniRef50_A7IMM1 Cluster: Short-chain dehydrogenase/reductase SDR...    73   6e-12
UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain dehydrogena...    73   6e-12
UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR...    73   6e-12
UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627;...    73   6e-12
UniRef50_P50197 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    73   6e-12
UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60; Bacteria|...    73   6e-12
UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oc...    73   8e-12
UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular o...    73   8e-12
UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase prec...    73   8e-12
UniRef50_O33454 Cluster: P-cumic alcohol dehydrogenase; n=3; Pro...    73   8e-12
UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR...    73   8e-12
UniRef50_Q0D3V4 Cluster: Os07g0664000 protein; n=34; cellular or...    73   8e-12
UniRef50_Q9VU92 Cluster: CG8757-PA; n=3; Drosophila melanogaster...    73   8e-12
UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_Q13H99 Cluster: Putative short-chain dehydrogenase/redu...    72   1e-11
UniRef50_Q0M0K7 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_Q54D03 Cluster: Putative uncharacterized protein; n=1; ...    72   1e-11
UniRef50_Q22RI1 Cluster: Oxidoreductase, short chain dehydrogena...    72   1e-11
UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh...    72   1e-11
UniRef50_UPI00015B572E Cluster: PREDICTED: similar to putative a...    72   1e-11
UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n...    72   1e-11
UniRef50_Q5LMX2 Cluster: 20-beta-hydroxysteroid dehydrogenase, p...    72   1e-11
UniRef50_Q11ZZ1 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_A6W2S3 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_A4TBK3 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR...    72   1e-11
UniRef50_A7S4C5 Cluster: Predicted protein; n=1; Nematostella ve...    72   1e-11
UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular organisms...    72   1e-11
UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=...    72   1e-11
UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34; Proteo...    72   1e-11
UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59; cell...    72   1e-11
UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3; Clo...    72   1e-11
UniRef50_Q89UC3 Cluster: D-beta-hydroxybutyrate dehydrogenase; n...    71   2e-11
UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=...    71   2e-11
UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR...    71   2e-11
UniRef50_A5WHV5 Cluster: Short-chain dehydrogenase/reductase SDR...    71   2e-11
UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR...    71   2e-11
UniRef50_A4ALI9 Cluster: Putative short chain dehydrogenase; n=2...    71   2e-11
UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bac...    71   2e-11
UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain dehydrogena...    71   2e-11
UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR...    71   2e-11
UniRef50_A0Z215 Cluster: Short chain dehydrogenase; n=2; Gammapr...    71   2e-11
UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR...    71   2e-11
UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family memb...    71   2e-11
UniRef50_P39071 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate dehyd...    71   2e-11
UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|R...    71   3e-11
UniRef50_A6VY27 Cluster: Short-chain dehydrogenase/reductase SDR...    71   3e-11
UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte...    71   3e-11
UniRef50_A0PSR4 Cluster: Short-chain dehydrogenase; n=1; Mycobac...    71   3e-11
UniRef50_Q6NNV7 Cluster: RH03309p; n=4; melanogaster subgroup|Re...    71   3e-11
UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    71   3e-11
UniRef50_Q62E12 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    71   3e-11
UniRef50_Q2S7V4 Cluster: Short-chain alcohol dehydrogenase-like ...    71   3e-11
UniRef50_Q3EU48 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    71   3e-11
UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR...    71   3e-11
UniRef50_A4T9G9 Cluster: Short-chain dehydrogenase/reductase SDR...    71   3e-11
UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogena...    71   3e-11
UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogena...    71   3e-11
UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR...    71   3e-11
UniRef50_Q2FSZ0 Cluster: Short-chain dehydrogenase/reductase SDR...    71   3e-11
UniRef50_Q48I17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    70   4e-11
UniRef50_Q02AD5 Cluster: Short-chain dehydrogenase/reductase SDR...    70   4e-11
UniRef50_A5V545 Cluster: Short-chain dehydrogenase/reductase SDR...    70   4e-11
UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR...    70   4e-11
UniRef50_A1UAJ6 Cluster: Acetoin reductases; n=18; Bacteria|Rep:...    70   4e-11
UniRef50_Q965D6 Cluster: 3-oxoacyl-acyl-carrier protein reductas...    70   4e-11
UniRef50_O15744 Cluster: PksB; n=2; Dictyostelium discoideum|Rep...    70   4e-11
UniRef50_Q9C826 Cluster: Xanthoxin dehydrogenase; n=41; Magnolio...    70   4e-11
UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia succinici...    70   6e-11
UniRef50_Q54472 Cluster: Oxido-reductase; n=3; Bacteria|Rep: Oxi...    70   6e-11
UniRef50_Q11E37 Cluster: Short-chain dehydrogenase/reductase SDR...    70   6e-11
UniRef50_A6BFV0 Cluster: Putative uncharacterized protein; n=1; ...    70   6e-11
UniRef50_A4M6M0 Cluster: Short-chain dehydrogenase/reductase SDR...    70   6e-11
UniRef50_A4B8L3 Cluster: Short chain dehydrogenase; n=1; Alterom...    70   6e-11
UniRef50_A3JFT9 Cluster: Short chain dehydrogenase; n=1; Marinob...    70   6e-11
UniRef50_A3IK59 Cluster: Oxidoreductase, short chain dehydrogena...    70   6e-11
UniRef50_A0Z7K1 Cluster: Short-chain dehydrogenase/reductase SDR...    70   6e-11
UniRef50_A7EQI6 Cluster: Putative uncharacterized protein; n=1; ...    70   6e-11
UniRef50_Q92EK7 Cluster: Uncharacterized oxidoreductase Lin0452;...    70   6e-11
UniRef50_Q8EQ60 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe...    69   8e-11
UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogena...    69   8e-11
UniRef50_Q7NCW8 Cluster: Gll2858 protein; n=6; Bacteria|Rep: Gll...    69   8e-11
UniRef50_Q39TR6 Cluster: Short-chain dehydrogenase/reductase SDR...    69   8e-11
UniRef50_Q0SC53 Cluster: Dehydrogenase; n=3; Corynebacterineae|R...    69   8e-11
UniRef50_A6LUV1 Cluster: Short-chain dehydrogenase/reductase SDR...    69   8e-11
UniRef50_A6EZZ8 Cluster: Short chain dehydrogenase; n=1; Marinob...    69   8e-11
UniRef50_Q0D3U7 Cluster: Os07g0665000 protein; n=18; Poales|Rep:...    69   8e-11
UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellula...    69   8e-11
UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    69   8e-11
UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    69   1e-10
UniRef50_Q8CNF1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    69   1e-10
UniRef50_Q88SD1 Cluster: Short-chain dehydrogenase/oxidoreductas...    69   1e-10
UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    69   1e-10
UniRef50_Q70I08 Cluster: Putative ketoreductase; n=1; Streptomyc...    69   1e-10
UniRef50_Q1VWP8 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_Q1V2H3 Cluster: Short chain dehydrogenase; n=2; Candida...    69   1e-10
UniRef50_Q1IP02 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_Q0B2G1 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_A7AZH2 Cluster: Putative uncharacterized protein; n=1; ...    69   1e-10
UniRef50_A6EGH2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    69   1e-10
UniRef50_A3XPR1 Cluster: Cyclohexanol dehydrogenase; n=1; Leeuwe...    69   1e-10
UniRef50_A1UEP6 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_UPI0000DB6B86 Cluster: PREDICTED: similar to CG9360-PA;...    69   1e-10
UniRef50_UPI0000518CA5 Cluster: PREDICTED: similar to antdh CG13...    69   1e-10
UniRef50_Q8YLL2 Cluster: Alr5286 protein; n=10; Cyanobacteria|Re...    69   1e-10
UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase pre...    69   1e-10
UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_Q26DV9 Cluster: Short-chain dehydrogenases/reductases f...    69   1e-10
UniRef50_Q1DDT9 Cluster: Oxidoreductase, short chain dehydrogena...    69   1e-10
UniRef50_Q12G63 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_Q07KD0 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_A4BGV8 Cluster: Short chain dehydrogenase; n=1; Reineke...    69   1e-10
UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR...    69   1e-10
UniRef50_Q7SI45 Cluster: Putative uncharacterized protein NCU006...    69   1e-10
UniRef50_A2QS57 Cluster: Contig An08c0220, complete genome; n=2;...    69   1e-10
UniRef50_P19992 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh...    69   1e-10
UniRef50_Q56840 Cluster: 2-(R)-hydroxypropyl-CoM dehydrogenase; ...    69   1e-10
UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2; Streptomyc...    68   2e-10
UniRef50_Q988B7 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    68   2e-10
UniRef50_Q8EPA2 Cluster: Hypothetical conserved protein; n=1; Oc...    68   2e-10
UniRef50_Q890G1 Cluster: Short-chain dehydrogenase/oxidoreductas...    68   2e-10
UniRef50_Q390G9 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_Q3W0V5 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_Q1DCG1 Cluster: Oxidoreductase, short-chain dehydrogena...    68   2e-10
UniRef50_Q0RTV0 Cluster: Short-chain dehydrogenase, SDR family; ...    68   2e-10
UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    68   2e-10
UniRef50_A1ZK52 Cluster: Dehydrogenase/reductase SDR family memb...    68   2e-10
UniRef50_A0M3M9 Cluster: Short-chain dehydrogenase/reductase fam...    68   2e-10
UniRef50_UPI000050F9D4 Cluster: COG1028: Dehydrogenases with dif...    68   2e-10
UniRef50_Q9ABX6 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    68   2e-10
UniRef50_Q8KKW9 Cluster: Putative oxidoreductase protein; n=1; R...    68   2e-10
UniRef50_Q5NM60 Cluster: Short-chain alcohol dehydrogenase; n=14...    68   2e-10
UniRef50_Q55922 Cluster: Slr0315 protein; n=2; Bacteria|Rep: Slr...    68   2e-10
UniRef50_Q3IKU0 Cluster: Putative 3-oxoacyl-[acyl-carrier protei...    68   2e-10
UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_Q1YZB6 Cluster: Short chain dehydrogenase; n=6; Gammapr...    68   2e-10
UniRef50_Q1NCX9 Cluster: Putative uncharacterized protein; n=1; ...    68   2e-10
UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_Q13GX3 Cluster: Putative short-chain dehydrogenase/redu...    68   2e-10
UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A6T789 Cluster: Putative short-chain dehydrogenase/redu...    68   2e-10
UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    68   2e-10
UniRef50_A3I6G4 Cluster: Putative 7-alpha-hydroxysteroid dehydro...    68   2e-10
UniRef50_A1U9L1 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A0PSE4 Cluster: Short-chain type dehydrogenase; n=12; C...    68   2e-10
UniRef50_A0G4K1 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_A0FY63 Cluster: Short-chain dehydrogenase/reductase SDR...    68   2e-10
UniRef50_Q2UV13 Cluster: Reductases with broad range of substrat...    68   2e-10
UniRef50_P40747 Cluster: Uncharacterized oxidoreductase yuxG; n=...    68   2e-10
UniRef50_Q833Z8 Cluster: Short chain dehydrogenase; n=23; Bacill...    67   3e-10
UniRef50_Q81WX9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    67   3e-10
UniRef50_Q7UJY8 Cluster: Probable short-chain dehydrogenase; n=1...    67   3e-10
UniRef50_Q62GZ1 Cluster: Oxidoreductase, short chain dehydrogena...    67   3e-10
UniRef50_Q2IEG2 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_Q12QC5 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_A4QHZ4 Cluster: Putative uncharacterized protein; n=1; ...    67   3e-10
UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_A0KYX3 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_A0JVB1 Cluster: Short-chain dehydrogenase/reductase SDR...    67   3e-10
UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1;...    67   3e-10
UniRef50_UPI00015B5DCD Cluster: PREDICTED: similar to oxidoreduc...    67   4e-10
UniRef50_Q829D6 Cluster: Putative dehydrogenase; n=2; Streptomyc...    67   4e-10
UniRef50_Q7W386 Cluster: Short chain dehydrogenase; n=111; cellu...    67   4e-10
UniRef50_Q6N3Z0 Cluster: Putative short-chain dehydrogenase/redu...    67   4e-10
UniRef50_Q62E13 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...    67   4e-10
UniRef50_Q62CL0 Cluster: D-beta-hydroxybutyrate dehydrogenase; n...    67   4e-10
UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxid...    67   4e-10
UniRef50_Q39TI0 Cluster: Short-chain dehydrogenase/reductase SDR...    67   4e-10
UniRef50_Q2SKD5 Cluster: Short-chain dehydrogenase of various su...    67   4e-10
UniRef50_Q2AGJ3 Cluster: NAD-dependent epimerase/dehydratase:Sho...    67   4e-10
UniRef50_A6WBU5 Cluster: Short-chain dehydrogenase/reductase SDR...    67   4e-10
UniRef50_A6W2Z2 Cluster: Short-chain dehydrogenase/reductase SDR...    67   4e-10
UniRef50_A6GFU2 Cluster: Short chain dehydrogenase; n=1; Plesioc...    67   4e-10
UniRef50_A4TAB8 Cluster: Short-chain dehydrogenase/reductase SDR...    67   4e-10
UniRef50_Q4J9S4 Cluster: Glucose 1-dehydrogenase; n=6; Thermopro...    67   4e-10
UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR...    67   4e-10
UniRef50_P54554 Cluster: Uncharacterized oxidoreductase yqjQ; n=...    67   4e-10
UniRef50_UPI00015B452D Cluster: PREDICTED: similar to ENSANGP000...    66   6e-10
UniRef50_UPI0000DB6BA4 Cluster: PREDICTED: similar to 3-hydroxya...    66   6e-10
UniRef50_Q988J7 Cluster: Oxidoreductase, short chain dehydrogena...    66   6e-10
UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specifici...    66   6e-10
UniRef50_Q87GW0 Cluster: Acetoacetyl-CoA reductase; n=7; Vibrio|...    66   6e-10
UniRef50_Q7VXT8 Cluster: Probable short-chain dehydrogenase; n=3...    66   6e-10
UniRef50_Q9S3U5 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n...    66   6e-10
UniRef50_Q84EX5 Cluster: R-specific alcohol dehydrogenase; n=5; ...    66   6e-10
UniRef50_Q3S8D5 Cluster: Putative short-chain dehydrogenase/redu...    66   6e-10
UniRef50_Q1ZIL9 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc...    66   6e-10
UniRef50_Q1YQ07 Cluster: Putative uncharacterized protein; n=1; ...    66   6e-10
UniRef50_Q1YPA9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati...    66   6e-10
UniRef50_Q081K4 Cluster: Short-chain dehydrogenase/reductase SDR...    66   6e-10
UniRef50_A7A2R8 Cluster: Putative uncharacterized protein; n=1; ...    66   6e-10
UniRef50_A5GRS5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    66   6e-10
UniRef50_A4AQP7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc...    66   6e-10
UniRef50_A1ZGN7 Cluster: Short-chain dehydrogenase/reductase SDR...    66   6e-10
UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR...    66   6e-10
UniRef50_A0YCW9 Cluster: Putative 3-oxoacyl-acyl carrier protein...    66   6e-10
UniRef50_P46331 Cluster: Uncharacterized oxidoreductase yxbG; n=...    66   6e-10
UniRef50_A4XEV7 Cluster: Short-chain dehydrogenase/reductase SDR...    44   6e-10
UniRef50_UPI000023F0AD Cluster: hypothetical protein FG09028.1; ...    66   7e-10
UniRef50_UPI000023CB88 Cluster: hypothetical protein FG04599.1; ...    66   7e-10
UniRef50_Q930L5 Cluster: Putative; n=3; Proteobacteria|Rep: Puta...    66   7e-10
UniRef50_Q92A39 Cluster: Lin2083 protein; n=16; Bacilli|Rep: Lin...    66   7e-10
UniRef50_Q8UHH7 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    66   7e-10
UniRef50_Q65F37 Cluster: Putative uncharacterized protein; n=1; ...    66   7e-10
UniRef50_Q2RUY0 Cluster: Short-chain dehydrogenase/reductase SDR...    66   7e-10
UniRef50_Q93QG5 Cluster: Cyclohexanol dehydrogenase; n=4; Bacter...    66   7e-10
UniRef50_Q5KRC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    66   7e-10
UniRef50_Q13HC1 Cluster: Putative short-chain dehydrogenase/redu...    66   7e-10
UniRef50_Q11BT8 Cluster: Short-chain dehydrogenase/reductase SDR...    66   7e-10
UniRef50_Q0TM71 Cluster: Oxidoreductase, short chain dehydrogena...    66   7e-10
UniRef50_Q0S4U3 Cluster: Dehydrogenase; n=2; Actinomycetales|Rep...    66   7e-10
UniRef50_A6X7S0 Cluster: Short-chain dehydrogenase/reductase SDR...    66   7e-10
UniRef50_A6W9N2 Cluster: Short-chain dehydrogenase/reductase SDR...    66   7e-10
UniRef50_A4ABL9 Cluster: Short-chain dehydrogenase/reductase SDR...    66   7e-10
UniRef50_A3ET57 Cluster: Short-chain alcohol dehydrogenase; n=2;...    66   7e-10
UniRef50_A0JVX6 Cluster: Short-chain dehydrogenase/reductase SDR...    66   7e-10
UniRef50_Q9VYU9 Cluster: CG9360-PA; n=12; Diptera|Rep: CG9360-PA...    66   7e-10
UniRef50_Q7Q3Q2 Cluster: ENSANGP00000007118; n=1; Anopheles gamb...    66   7e-10
UniRef50_Q16Q07 Cluster: Alcohol dehydrogenase, putative; n=1; A...    66   7e-10
UniRef50_Q0U1A7 Cluster: Putative uncharacterized protein; n=1; ...    66   7e-10
UniRef50_Q9Y394 Cluster: Dehydrogenase/reductase SDR family memb...    66   7e-10
UniRef50_Q8UAB0 Cluster: Dehydrogenase; n=1; Agrobacterium tumef...    66   1e-09
UniRef50_Q89WX4 Cluster: Short-chain dehydrogenase; n=11; Bradyr...    66   1e-09
UniRef50_Q88T73 Cluster: Short-chain dehydrogenase/oxidoreductas...    66   1e-09
UniRef50_Q65SP1 Cluster: FabG protein; n=10; Bacteria|Rep: FabG ...    66   1e-09
UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR...    66   1e-09
UniRef50_Q140J4 Cluster: Putative 3-oxoacyl-(Acyl-carrier protei...    66   1e-09
UniRef50_Q0FWE6 Cluster: Putative oxidoreductase; n=1; Roseovari...    66   1e-09
UniRef50_A7IJ54 Cluster: Short-chain dehydrogenase/reductase SDR...    66   1e-09
UniRef50_A6C1M0 Cluster: Short chain dehydrogenase; n=1; Plancto...    66   1e-09
UniRef50_A1K1F4 Cluster: Short-chain dehydrogenase family protei...    66   1e-09
UniRef50_A0UZI2 Cluster: Short-chain dehydrogenase/reductase SDR...    66   1e-09
UniRef50_A0R6X9 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte...    66   1e-09
UniRef50_Q0DM18 Cluster: Os03g0833100 protein; n=5; Oryza sativa...    66   1e-09
UniRef50_Q6IDG8 Cluster: RH36352p; n=2; Drosophila melanogaster|...    66   1e-09
UniRef50_A0DCG9 Cluster: Chromosome undetermined scaffold_45, wh...    66   1e-09
UniRef50_A2BJK2 Cluster: Short chain dehydrogenase; n=1; Hyperth...    66   1e-09
UniRef50_P37079 Cluster: Sorbitol-6-phosphate 2-dehydrogenase; n...    66   1e-09
UniRef50_UPI000050F7E5 Cluster: COG1028: Dehydrogenases with dif...    65   1e-09
UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    65   1e-09
UniRef50_Q6MBQ9 Cluster: Putative uncharacterized protein; n=1; ...    65   1e-09
UniRef50_Q8GR61 Cluster: Xylitol dehydrogenase; n=2; Gluconobact...    65   1e-09
UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2; Corynebac...    65   1e-09
UniRef50_Q1YS63 Cluster: Putative dehydrogenase; n=1; gamma prot...    65   1e-09
UniRef50_Q1AYC7 Cluster: Short-chain dehydrogenase/reductase SDR...    65   1e-09
UniRef50_Q0S7P7 Cluster: Short chain dehydrogenase; n=7; Bacteri...    65   1e-09
UniRef50_Q0B254 Cluster: Short-chain dehydrogenase/reductase SDR...    65   1e-09
UniRef50_A7U537 Cluster: Short-chain dehydrogenase/reductase; n=...    65   1e-09
UniRef50_A6CW76 Cluster: Putative short chain dehydrogenase; n=1...    65   1e-09
UniRef50_A4CPX8 Cluster: Short chain dehydrogenase; n=2; Bacteri...    65   1e-09
UniRef50_A2U5Y6 Cluster: Short-chain dehydrogenase/reductase SDR...    65   1e-09
UniRef50_A1ULZ8 Cluster: Short-chain dehydrogenase/reductase SDR...    65   1e-09
UniRef50_Q75DB1 Cluster: ABR248Wp; n=4; Eremothecium gossypii|Re...    65   1e-09
UniRef50_Q6CFW0 Cluster: Yarrowia lipolytica chromosome B of str...    65   1e-09
UniRef50_Q8TTL5 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    65   1e-09
UniRef50_Q8TMH3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    65   1e-09
UniRef50_UPI00004996DD Cluster: 3-oxoacyl-(acyl-carrier protein)...    65   2e-09
UniRef50_Q8YVT0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    65   2e-09
UniRef50_Q8DIS9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    65   2e-09
UniRef50_Q7ULD3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    65   2e-09
UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR...    65   2e-09
UniRef50_Q39N51 Cluster: Short-chain dehydrogenase/reductase SDR...    65   2e-09
UniRef50_Q2GA84 Cluster: Short-chain dehydrogenase/reductase SDR...    65   2e-09
UniRef50_Q2IVE1 Cluster: Short-chain dehydrogenase/reductase SDR...    65   2e-09
UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified Gamma...    65   2e-09
UniRef50_Q12B22 Cluster: Short-chain dehydrogenase/reductase SDR...    65   2e-09
UniRef50_Q0VQZ0 Cluster: Oxidoreductase; n=4; Gammaproteobacteri...    65   2e-09
UniRef50_Q0SJT0 Cluster: Short chain dehydrogenase; n=13; Actino...    65   2e-09
UniRef50_Q029B5 Cluster: Short-chain dehydrogenase/reductase SDR...    65   2e-09
UniRef50_A7IJL6 Cluster: Short-chain dehydrogenase/reductase SDR...    65   2e-09
UniRef50_A7DJ01 Cluster: Short-chain dehydrogenase/reductase SDR...    65   2e-09
UniRef50_A5MZ18 Cluster: FabG2; n=2; Clostridia|Rep: FabG2 - Clo...    65   2e-09
UniRef50_A3JK09 Cluster: Oxidoreductase; n=1; Marinobacter sp. E...    65   2e-09
UniRef50_A6XGT9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    65   2e-09
UniRef50_Q9N5G3 Cluster: Dehydrogenases, short chain protein 14;...    65   2e-09
UniRef50_Q4WR19 Cluster: Short chain dehydrogenase, putative; n=...    65   2e-09
UniRef50_Q2UTV6 Cluster: Dehydrogenases with different specifici...    65   2e-09
UniRef50_A5DPQ3 Cluster: Putative uncharacterized protein; n=2; ...    65   2e-09
UniRef50_A3H6D0 Cluster: Short-chain dehydrogenase/reductase SDR...    65   2e-09
UniRef50_Q9RKB7 Cluster: Probable 3-oxoacyl-[acyl carrier protei...    64   2e-09
UniRef50_Q97NV2 Cluster: Oxidoreductase, short chain dehydrogena...    64   2e-09
UniRef50_Q8EDE2 Cluster: Oxidoreductase, short chain dehydrogena...    64   2e-09
UniRef50_Q7MAW1 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    64   2e-09
UniRef50_Q2KXQ0 Cluster: Probable short chain dehydrogenase/redu...    64   2e-09
UniRef50_Q7P5A9 Cluster: Ketoacyl reductase hetN; n=3; Fusobacte...    64   2e-09
UniRef50_Q2IVN1 Cluster: Short-chain dehydrogenase/reductase; n=...    64   2e-09
UniRef50_Q1ILJ4 Cluster: Short-chain dehydrogenase/reductase SDR...    64   2e-09
UniRef50_Q11G59 Cluster: Short-chain dehydrogenase/reductase SDR...    64   2e-09
UniRef50_A5TX02 Cluster: Short-chain alcohol dehydrogenase; n=3;...    64   2e-09
UniRef50_A4WBV4 Cluster: Short-chain dehydrogenase/reductase SDR...    64   2e-09
UniRef50_A4ET39 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc...    64   2e-09
UniRef50_A3SL40 Cluster: Putative uncharacterized protein; n=1; ...    64   2e-09
UniRef50_A0YDM1 Cluster: Putative 3-ketoacyl-CoA reductase; n=3;...    64   2e-09
UniRef50_A0XX22 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    64   2e-09
UniRef50_A0QGC5 Cluster: Sorbitol utilization protein SOU1; n=3;...    64   2e-09
UniRef50_A0GDT9 Cluster: Short-chain dehydrogenase/reductase SDR...    64   2e-09
UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methano...    64   2e-09
UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR...    64   2e-09
UniRef50_Q9AK65 Cluster: Putative glucose 1-dehydrogenase; n=2; ...    64   3e-09
UniRef50_Q3WFP9 Cluster: Short-chain dehydrogenase/reductase SDR...    64   3e-09
UniRef50_Q2BDF6 Cluster: Putative uncharacterized protein; n=1; ...    64   3e-09
UniRef50_Q1NK00 Cluster: Short-chain dehydrogenase/reductase SDR...    64   3e-09
UniRef50_Q13I70 Cluster: Putative short-chain dehydrogenase/redu...    64   3e-09
UniRef50_Q11BT3 Cluster: Short-chain dehydrogenase/reductase SDR...    64   3e-09
UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR...    64   3e-09
UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR...    64   3e-09
UniRef50_A6ELE5 Cluster: Short-chain dehydrogenase/reductase SDR...    64   3e-09
UniRef50_A5P5M1 Cluster: Short-chain dehydrogenase/reductase SDR...    64   3e-09
UniRef50_A4XEP3 Cluster: Short-chain dehydrogenase/reductase SDR...    64   3e-09
UniRef50_A4BWQ4 Cluster: Putative short chain dehydrogenase; n=1...    64   3e-09
UniRef50_A3IBN0 Cluster: Predicted short chain dehydrogenase; n=...    64   3e-09

>UniRef50_Q1G151 Cluster: Putative alcohol dehydrogenase; n=1;
           Bombyx mori|Rep: Putative alcohol dehydrogenase - Bombyx
           mori (Silk moth)
          Length = 274

 Score =  175 bits (425), Expect = 1e-42
 Identities = 85/199 (42%), Positives = 126/199 (63%), Gaps = 1/199 (0%)
 Frame = +3

Query: 27  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKFYRS 203
           DKV  +TG A G+G  +V+ LL E  +H+A LD+A+  G +L+ +L  K+G  + KF + 
Sbjct: 14  DKVFLVTGGAAGVGAGLVKALLFENARHVAFLDVADREGAALEAQLIIKFGALRVKFIKC 73

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 383
           DV DE         V+ +   +D VIN+AA+++     + + I++N T  + STLKA++I
Sbjct: 74  DVGDERQLASAYKQVLDKYKRLDGVINSAAVLSVDDNSFNRMIDINFTGTVNSTLKALDI 133

Query: 384 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 563
           MG   GG GG ++N+SS+ AL  +  +P+Y ATK+AVLQFS  +G  E F++T VRVL+V
Sbjct: 134 MGADKGGSGGVIVNISSLLALNLTSHLPVYAATKAAVLQFSIRMGTQEQFTRTKVRVLSV 193

Query: 564 CFGATDTALLTDEKLGTFD 620
           C G TDTA+L    L  FD
Sbjct: 194 CLGPTDTAILYKNNLTKFD 212


>UniRef50_Q6RUR3 Cluster: Putative alcohol dehydrogenase; n=2;
           Neoptera|Rep: Putative alcohol dehydrogenase -
           Gryllotalpa orientalis (Oriental mole cricket)
          Length = 266

 Score =  157 bits (381), Expect = 2e-37
 Identities = 85/216 (39%), Positives = 124/216 (57%), Gaps = 4/216 (1%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 200
           K K   +TG ATGIG + V+ LL  GV+ +A+ D+ E  G +   +LN ++G  K  F +
Sbjct: 4   KGKYALVTGGATGIGLAYVKELLRHGVQAVAVADLDERKGDNSVKQLNDEFGAGKAIFIK 63

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 380
            DVT+++              G+D+VINNA +++DS   ++  I +NVTA+   T  A +
Sbjct: 64  CDVTNKDDLEATFRKAAATFKGLDIVINNAGILDDSR--WETEIAINVTAVARGTWLAFD 121

Query: 381 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
           +MGK+ GG+GG V+N++S+  L      P+Y ATK AV+  S   G P HF +TGVRVLT
Sbjct: 122 LMGKNKGGRGGVVVNIASILGLQAMAGCPVYVATKHAVVGLSRSFGMPYHFDRTGVRVLT 181

Query: 561 VCFGATDTALLTDEKLGTFDKYLESSC---LDQLKK 659
           +C G TDT L+++     F   L   C   LD L K
Sbjct: 182 MCPGVTDTPLISEAHHRQFTDDLGKECGRELDALPK 217


>UniRef50_Q6NYE8 Cluster: Zgc:56585 protein; n=5; Clupeocephala|Rep:
           Zgc:56585 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 270

 Score =  153 bits (372), Expect = 3e-36
 Identities = 81/208 (38%), Positives = 126/208 (60%), Gaps = 5/208 (2%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 200
           KDKV  +TGAA G+G S V IL+  G K +A++D+ +  G+ L+  LN +YG N+ +FY 
Sbjct: 4   KDKVAVVTGAAQGLGRSFVEILMKNGSK-VALIDVNKSLGEELKTNLNKEYGPNRAEFYT 62

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 380
           +DV+ EE F G+L  +V++ G ID++ NNA ++N+    ++K I +N+  ++  T  A+E
Sbjct: 63  ADVSSEEDFKGVLKKIVEQFGQIDIMCNNAGIINEKH--WEKTIAINLGGVVRGTYLALE 120

Query: 381 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
            M K +GG GG ++NV+S+A L    V PIY ATK  V+ FS  +      S  GVR+  
Sbjct: 121 YMKKENGGSGGVIVNVASMAGLGPLPVAPIYTATKHGVVGFSRAMAVVSKLSNYGVRINV 180

Query: 561 VCFGATDTALL----TDEKLGTFDKYLE 632
           +C     T+LL    ++E  G+F +  E
Sbjct: 181 LCPWFVKTSLLSLLNSEEHTGSFSQMKE 208


>UniRef50_UPI0000DB7440 Cluster: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase; n=1; Apis
           mellifera|Rep: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase - Apis mellifera
          Length = 266

 Score =  149 bits (360), Expect = 8e-35
 Identities = 75/182 (41%), Positives = 117/182 (64%), Gaps = 1/182 (0%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 200
           KDK V ITG A+G+G ++ R LL  G   IA++D AEE+GK     LN ++G N+T FY 
Sbjct: 4   KDKRVIITGVASGLGLTISRELLRNGASIIAMID-AEESGKETVDILNKEFGRNRTIFYH 62

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 380
            ++ +   F       V+  GG+++++NNA + N++   + K I+VNVT++I +TL  I+
Sbjct: 63  CNIANNSEFDDTFKKAVKALGGLEILVNNADVTNETD--FMKTIDVNVTSVIRATLLGIQ 120

Query: 381 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
            M K  GGKGG ++N+SS+A L  +  +P+Y ATK AV+ FS    +P H+ +TGV++L 
Sbjct: 121 QMQKDLGGKGGAIVNISSLAGLYAAPQLPVYSATKHAVVSFSRSFAQPYHYKRTGVKILV 180

Query: 561 VC 566
           +C
Sbjct: 181 MC 182


>UniRef50_UPI00015B5316 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 329

 Score =  142 bits (343), Expect = 9e-33
 Identities = 69/195 (35%), Positives = 115/195 (58%), Gaps = 1/195 (0%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 200
           KDK   + GA  G+G +  + LL  GV  + ++D+ E  G++    LN ++G N+  F +
Sbjct: 71  KDKKAMVIGACDGLGMAFSKELLRNGVARVLMIDMNETLGRAQADRLNEEFGRNRATFTK 130

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 380
            DVT    F       V   G +D+++NNAA++ D +  ++  I+ NVTA+  +++  ++
Sbjct: 131 CDVTKGSEFDACFKDAVNTLGALDIIVNNAAMI-DEVNFHR-TIDTNVTAVFRASMMGVQ 188

Query: 381 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
            MGK +GGKGG ++NV+SV  L     +PIY AT  AV+ FS    +P H+ +TGVR++ 
Sbjct: 189 QMGKDTGGKGGVIVNVASVLGLEACPQLPIYSATNHAVIAFSRSFSQPYHYQRTGVRLMV 248

Query: 561 VCFGATDTALLTDEK 605
           +C G T++ +L + K
Sbjct: 249 LCPGLTESPMLENLK 263


>UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 261

 Score =  142 bits (343), Expect = 9e-33
 Identities = 70/191 (36%), Positives = 118/191 (61%), Gaps = 1/191 (0%)
 Frame = +3

Query: 27  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
           +KV  ITG A GIG ++V+ LL+ G+K +A+ D+     K + ++L  KYGN+ + Y  D
Sbjct: 5   NKVAIITGGAGGIGAAIVKRLLEHGIKLVALFDLDNSNTKKIFMDLQKKYGNRVELYPCD 64

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK-AIEVNVTALITSTLKAIEI 383
           VT++  F    + V++    ID+++NNA + +D   I+ +  I++N  A++  +L  IE 
Sbjct: 65  VTNKAQFEENFDKVLKTHKTIDILLNNAGIGSD---IHTELMIDLNYKAVVLGSLLFIER 121

Query: 384 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 563
           +GKH GGKGG ++N +S+  L     +P+Y +TK AV+ F+ C+     +  TGVRV+ +
Sbjct: 122 LGKHKGGKGGIIVNTASILGLRNFDCLPVYCSTKHAVVSFTRCL--DVQYDTTGVRVVAI 179

Query: 564 CFGATDTALLT 596
           C G T+T L++
Sbjct: 180 CPGVTETPLVS 190


>UniRef50_UPI00015B4C63 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 271

 Score =  139 bits (337), Expect = 5e-32
 Identities = 72/202 (35%), Positives = 118/202 (58%), Gaps = 8/202 (3%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKF 194
           E  +KV+ ITG   G+G    + LL+ G K +A+ D+ E  G+S   +L+ ++G  +  F
Sbjct: 2   EISNKVIIITGGVGGMGFETAKALLNHGAKFVALFDLTETDGQSAIEKLDKEFGKGRAGF 61

Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALI------ 356
           Y  D+  +  F    N ++++ G IDV+INNA + N+     ++ + VNV + I      
Sbjct: 62  YPGDIVIDSEFEDNFNRIIKDHGSIDVLINNAGIANEQN--IERLVNVNVVSSIDKNILR 119

Query: 357 -TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533
            +  L A+  MGKH GGKGG ++NV+++  L    ++P Y ATK A++ F+ C+   E+F
Sbjct: 120 ASQILLALNHMGKHKGGKGGAIVNVNAILGLIDCPILPFYSATKHAIIGFTRCM--KENF 177

Query: 534 SKTGVRVLTVCFGATDTALLTD 599
           + TGVRV++VC G T T L+ +
Sbjct: 178 ATTGVRVMSVCPGVTKTNLIKE 199


>UniRef50_UPI0000513348 Cluster: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase; n=2; Apis
           mellifera|Rep: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase - Apis mellifera
          Length = 263

 Score =  139 bits (336), Expect = 6e-32
 Identities = 73/205 (35%), Positives = 118/205 (57%), Gaps = 1/205 (0%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-K 185
           M+   K+K   ITG   G+G    + LL+ G K +A+LD++   G+     L  ++G  K
Sbjct: 1   MTDNIKNKTALITGGTVGLGLIYAKRLLENGAKCVALLDLSSSPGQQTVNNLEKEFGKGK 60

Query: 186 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 365
             FY  DV++   F  +   VV +  G+D+VINNA + ND    +++ + +NV  +I  +
Sbjct: 61  AIFYACDVSNINEFEAVFKKVVNDLNGLDIVINNAGIYNDKK--WEQTMCINVGGVIQGS 118

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
           L A + M K  GGKGGT++N++S+ AL   +  P+Y A+K  VL FS  + R  +++ TG
Sbjct: 119 LLAFDHMSKLKGGKGGTIVNIASIVALDIIYSNPVYCASKHFVLAFSRSLAR--YYNNTG 176

Query: 546 VRVLTVCFGATDTALLTDEKLGTFD 620
           +R+L +C G T T+LL +    +FD
Sbjct: 177 IRILIMCPGVTTTSLLENPLSKSFD 201


>UniRef50_UPI00015B573D Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 279

 Score =  136 bits (330), Expect = 3e-31
 Identities = 73/204 (35%), Positives = 118/204 (57%), Gaps = 1/204 (0%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 200
           KDKV+ +TG A GIG   V   L++G +++AILDI  E       +L  ++G ++   Y 
Sbjct: 11  KDKVIIVTGGANGIGLECVLEFLEKGARYVAILDITPE--NFTADKLQEEFGTHRVDLYH 68

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 380
            D+ +EE F      V+++   +D++IN+A + N++     + ++VNV   I   L AIE
Sbjct: 69  CDIANEEEFRSNFKKVIEKHNYVDILINDAGVANENDTA--RLLDVNVKGTILGNLMAIE 126

Query: 381 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
            MGKH GG+GG V+NV+SV  L   HV+P+Y A+K A++ F+  +    +  + GV+++ 
Sbjct: 127 HMGKHKGGRGGVVVNVASVIGLLNCHVLPVYSASKHAIVSFTRSM--KSNCDRLGVKIIA 184

Query: 561 VCFGATDTALLTDEKLGTFDKYLE 632
           VC G T T L  +  + T   YL+
Sbjct: 185 VCPGHTRTKLNFELAVETSVNYLD 208


>UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=3; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 273

 Score =  132 bits (318), Expect = 1e-29
 Identities = 67/192 (34%), Positives = 117/192 (60%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
           E KDKVV ITG  +GIG S+ + +L  G K++A+ ++  E  + +  EL+ +Y ++  FY
Sbjct: 19  EVKDKVVVITGGTSGIGLSIAKHMLKNGAKYVALFELDHENSRIVFDELHKQYHDRIGFY 78

Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 377
             DVT  +      + V++    ID++INNA + +D+    + ++++N+ AL+ ++ K I
Sbjct: 79  PCDVTKTDLIYNNFDKVMESHKTIDILINNAGIADDNKP--ELSVDINLKALVVASYKFI 136

Query: 378 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
             +GKH GGKGG ++N++S+A +  S  +P+Y ATK  V+ F+  +     +  TGVRVL
Sbjct: 137 ARIGKHKGGKGGVIVNIASIAGIV-SGFLPVYCATKHGVVGFTRTL--QMSYGLTGVRVL 193

Query: 558 TVCFGATDTALL 593
            +C   T+T ++
Sbjct: 194 AICPSFTNTPIV 205


>UniRef50_UPI00015B42E2 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 266

 Score =  131 bits (317), Expect = 1e-29
 Identities = 71/193 (36%), Positives = 113/193 (58%), Gaps = 3/193 (1%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQV--ELNSKYG-NKTKF 194
           KDKV  +TG   GIG + V+ LL  G K++AI D+     ++     ++  ++G +K  F
Sbjct: 4   KDKVAIVTGGTGGIGFATVQALLRHGAKYVAIFDLDSMHTRAASCIHKVEEEFGKDKADF 63

Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 374
           Y  DVT +  F    + +V  Q  +D+++N A++ ++    +   I++N+TA++T TL  
Sbjct: 64  YTCDVTIQSEFAARYDEIVGMQRTVDILVNYASIASEPRAHHM--IDINLTAVVTCTLIG 121

Query: 375 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
           I+ MG+H  G+GG ++NV SV  LT S   PIY ATK  V  F+  +   +H+   GVRV
Sbjct: 122 IDRMGRHHNGRGGAIVNVCSVFGLTTSPAFPIYTATKYGVYGFTKSL--KDHYEHLGVRV 179

Query: 555 LTVCFGATDTALL 593
           + VC G T+T+LL
Sbjct: 180 MAVCPGLTETSLL 192


>UniRef50_UPI000051334A Cluster: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH)
           (Prostaglandin dehydrogenase 1) isoform 1; n=1; Apis
           mellifera|Rep: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH)
           (Prostaglandin dehydrogenase 1) isoform 1 - Apis
           mellifera
          Length = 264

 Score =  128 bits (309), Expect = 1e-28
 Identities = 62/188 (32%), Positives = 111/188 (59%), Gaps = 1/188 (0%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 206
           K+  +TG A GIG    R LL  G K +A+LD+++  G+S   +LN+++G ++  F   D
Sbjct: 6   KIAIVTGGANGIGFCTARKLLRNGAKAVALLDLSDSGGESAAADLNNEFGKDRAIFIACD 65

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 386
           V+  E F      V+     +++++N A +M+D+   ++  +++N   ++  T+  +  M
Sbjct: 66  VSKNEQFQESFKKVIDTYETLNILVNIAGIMDDAD--WEIMVDINYKGIVYGTILGLHTM 123

Query: 387 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 566
           GK+ GG GG ++N+SSVA L    + PIY  T+ A++ F+  +    ++ KTG+R+LT+C
Sbjct: 124 GKYKGGNGGIIVNMSSVAGLEGIPIAPIYGGTQYAIVGFTQSL--KHYYEKTGIRMLTIC 181

Query: 567 FGATDTAL 590
            G T TA+
Sbjct: 182 PGLTTTAM 189


>UniRef50_UPI00015B5A58 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 263

 Score =  127 bits (306), Expect = 3e-28
 Identities = 70/193 (36%), Positives = 115/193 (59%), Gaps = 3/193 (1%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKS-LQVE-LNSKYGN-KTKF 194
           K+KV+ ITG   G+  +  ++LL    ++IA+ D  E+   + LQ++    ++G  +  F
Sbjct: 4   KNKVIIITGGLGGLATATTQVLLKHEPRYIALFDTEEKNSYAELQLKKFEQEFGEGRVGF 63

Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 374
           Y SDV ++  F    + V++    +D++IN A ++ D+    +  I+VN   L+  TL A
Sbjct: 64  YASDVRNQHQFEEKYDQVLKSHKSVDILINLAGILCDADT--ELTIDVNFKGLVFCTLTA 121

Query: 375 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
           I+ MG H GG+GGT+INVSS+  L      P+Y ATK AV+ F+N +    H++KTGVR 
Sbjct: 122 IDKMGIHRGGRGGTIINVSSIVGLMFHEDFPVYVATKHAVVAFTNSL--KSHYAKTGVRA 179

Query: 555 LTVCFGATDTALL 593
           +T+C G T T+++
Sbjct: 180 MTMCPGLTSTSMI 192


>UniRef50_UPI0000D57364 Cluster: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH)
           (Prostaglandin dehydrogenase 1); n=1; Tribolium
           castaneum|Rep: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH)
           (Prostaglandin dehydrogenase 1) - Tribolium castaneum
          Length = 312

 Score =  126 bits (304), Expect = 5e-28
 Identities = 66/188 (35%), Positives = 107/188 (56%), Gaps = 1/188 (0%)
 Frame = +3

Query: 33  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 209
           V  ITG A GIG ++ R+ L  G+  +A+ D ++E G+    +L  ++G NK  F+  D+
Sbjct: 54  VAIITGGAEGIGLAIARVFLKCGISGLAVADCSKEKGEESIKQLACEFGENKVLFFDGDM 113

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 389
           +  + F  +    +     +++V+NNA +MND    ++  +  N++  I  TL  ++ M 
Sbjct: 114 SQSKAFDRVFKETLNHFENVNIVVNNAGVMNDVN--WECQVNTNLSGTIIGTLLGMQYMS 171

Query: 390 KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCF 569
           K S G+GGT+INV+S+  L  S   PI+  T+  ++ FS  IG   HF +TGVRV  +C 
Sbjct: 172 KTSLGQGGTIINVASIMGLIPSSGYPIHTLTQFGIVGFSRAIGNLNHFDRTGVRVTALCP 231

Query: 570 GATDTALL 593
           G T+T LL
Sbjct: 232 GLTNTKLL 239


>UniRef50_UPI00015B5FC8 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=2; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 267

 Score =  125 bits (302), Expect = 9e-28
 Identities = 77/219 (35%), Positives = 126/219 (57%), Gaps = 6/219 (2%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE---EAGKSLQVELNSKYGNKT 188
           E K+KV  +TG   GIG   V+ L+   ++ +AI+D+ +   EA  +   +LN ++G  +
Sbjct: 2   EIKNKVAIVTGGIGGIGLVTVQHLIRSKIQFVAIIDLPKSDSEAAVANLSKLNKEFGKGS 61

Query: 189 -KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 365
            ++Y  D+T+ + F  I   V+  +  +D++IN A ++ND+       I VN TA++ S+
Sbjct: 62  YQYYSCDLTNIQEFRAIYEKVIALKKYVDILINAAGILNDNA--MNLCINVNFTAVVNSS 119

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
           + AIE M K  GGKGG V+NV+S+A +      PIY ATK AV+ F+  + +P H    G
Sbjct: 120 MIAIEHMRKDKGGKGGVVVNVASIAGIVDFPYNPIYNATKHAVVAFARSL-KP-HNKIIG 177

Query: 546 VRVLTVCFGATDTALLTDEKL--GTFDKYLESSCLDQLK 656
           VRV+ +C G TDT L+  + L    FD +++   +D  +
Sbjct: 178 VRVVCICPGVTDTGLVAFDHLYKSLFD-FIDPKIVDDFR 215


>UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|Rep:
           CG4899-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 278

 Score =  125 bits (301), Expect = 1e-27
 Identities = 68/199 (34%), Positives = 116/199 (58%), Gaps = 1/199 (0%)
 Frame = +3

Query: 6   KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNK 185
           KMS   K+ VV  TG A GIG  V + LL  G   +AI+D+ +   +   V+L + +  +
Sbjct: 17  KMSFRGKNAVV--TGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEF--VKLRAAHPTQ 72

Query: 186 T-KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITS 362
           +    + DV +++        + +  G ID+V+N A + ND     ++ + VN+  +I S
Sbjct: 73  SVMIIKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKD--VQRTLLVNLGGIINS 130

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
           TL A+  MGK +GGKGG V+N+SSV  L    ++P+Y ATK+ ++ F+ C+   +++ ++
Sbjct: 131 TLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRS 190

Query: 543 GVRVLTVCFGATDTALLTD 599
           G++ +TVC GAT T + T+
Sbjct: 191 GIKFVTVCPGATMTDMFTN 209


>UniRef50_Q1HPX6 Cluster: Alcohol dehydrogenase; n=1; Bombyx
           mori|Rep: Alcohol dehydrogenase - Bombyx mori (Silk
           moth)
          Length = 289

 Score =  124 bits (299), Expect = 2e-27
 Identities = 80/209 (38%), Positives = 112/209 (53%), Gaps = 3/209 (1%)
 Frame = +3

Query: 3   LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG- 179
           LK  +E + KVV ITGAA GIG ++    L  G K I ILDI    G     ELN KYG 
Sbjct: 25  LKKENEIEGKVVVITGAAQGIGYAIADNFLKNGAKVIIILDINVPKGIQAAKELNCKYGK 84

Query: 180 NKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALIT 359
           NK +F   D+T +     I   + ++   +DV++NNA +  +     +K +  N  A I 
Sbjct: 85  NKAEFIECDITKDLE--RISKIIYKKYKYVDVLVNNAGIFKEIKP--RKLLLTNAVATIE 140

Query: 360 STLKAIEIMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
            +LK +E M K    GKGGT+IN++S          P Y  TK A++ FS  +G   ++ 
Sbjct: 141 FSLKFMENMRKDKLSGKGGTIINIASTVVHYIDPFFPTYRGTKFAIMGFSRSLGHEYNYK 200

Query: 537 KTGVRVLTVCFGATDTAL-LTDEKLGTFD 620
           K GVRVLT+C G T+T L L + K+ + D
Sbjct: 201 KNGVRVLTICPGETNTTLGLDNTKVNSED 229


>UniRef50_P15428 Cluster: 15-hydroxyprostaglandin dehydrogenase
           [NAD+]; n=29; Euteleostomi|Rep: 15-hydroxyprostaglandin
           dehydrogenase [NAD+] - Homo sapiens (Human)
          Length = 266

 Score =  122 bits (293), Expect = 1e-26
 Identities = 66/203 (32%), Positives = 114/203 (56%), Gaps = 2/203 (0%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 206
           KV  +TGAA GIG +    LL +G K +A++D   EAG   +  L+ ++   KT F + D
Sbjct: 6   KVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 386
           V D++        VV   G +D+++NNA + N+    ++K +++N+ ++I+ T   ++ M
Sbjct: 65  VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN--WEKTLQINLVSVISGTYLGLDYM 122

Query: 387 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 566
            K +GG+GG +IN+SS+A L      P+Y A+K  ++ F+       +   +GVR+  +C
Sbjct: 123 SKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAIC 182

Query: 567 FGATDTALLTD-EKLGTFDKYLE 632
            G  +TA+L   EK     +Y+E
Sbjct: 183 PGFVNTAILESIEKEENMGQYIE 205


>UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 337

 Score =  121 bits (292), Expect = 1e-26
 Identities = 65/220 (29%), Positives = 118/220 (53%), Gaps = 1/220 (0%)
 Frame = +3

Query: 3   LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG- 179
           L++S     K V ITG A G+G +     L  G   I I+DI + AGK +    +  +G 
Sbjct: 37  LEISGVVSGKNVLITGGAAGLGHAFFNHFLQFGANKICIIDIDDVAGKKIVASTDKSHGV 96

Query: 180 NKTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALIT 359
            K  F  +DV+     +      V+    +D+V+NNA ++++    +++ I VN+  +I+
Sbjct: 97  GKVIFIHADVSRHSEIVAGFQKAVKLMDAVDIVVNNAGILDERR--WEREIAVNLNGMIS 154

Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
             L +++ MG+  GG+GG ++NV+    +  +  +P+Y ATK A++  S  +  P +  +
Sbjct: 155 VALLSMQYMGRDMGGRGGILVNVAEHMDVHCTAQLPVYTATKQAIIGLSQSLAAPCNTER 214

Query: 540 TGVRVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKK 659
           TGVRV+T+C G T+TAL  D       + +++  +  L++
Sbjct: 215 TGVRVITLCPGLTETALTIDSPNKLLSRVMKADFVKNLEQ 254


>UniRef50_UPI0000E47587 Cluster: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase (NAD+), partial;
           n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to 15-hydroxyprostaglandin dehydrogenase (NAD+),
           partial - Strongylocentrotus purpuratus
          Length = 298

 Score =  121 bits (292), Expect = 1e-26
 Identities = 68/202 (33%), Positives = 113/202 (55%), Gaps = 2/202 (0%)
 Frame = +3

Query: 6   KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-N 182
           K+  + +  V  ITGAA G G++    LL   V+ I I+D     GK+ + ELN KYG +
Sbjct: 37  KIKMKIQGAVALITGAAEGFGKAFTEELLKRSVRGIGIVDFNAAKGKATETELNKKYGED 96

Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITS 362
           K +F++ DV+ ++      +  ++   GID+V NNA +  D +  ++K ++V++ A++  
Sbjct: 97  KVRFFQCDVSSKDQLEDAFSKTLEHYKGIDIVCNNAGI-GDELN-WEKTVDVDLVAVMRG 154

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH-FSK 539
           T  A + M K+ GG+GG VIN++S+A L    + P Y A K  VL FS  +   +  F+ 
Sbjct: 155 TFLAKQYMDKNKGGRGGIVINIASMAGLYPMPLAPAYSAAKHGVLGFSRALAIADKVFNP 214

Query: 540 TGVRVLTVCFGATDTALLTDEK 605
             VR+  +C   ++TA+L   K
Sbjct: 215 ENVRLNCLCPSFSETAILQQMK 236


>UniRef50_Q7PY55 Cluster: ENSANGP00000013280; n=4;
           Endopterygota|Rep: ENSANGP00000013280 - Anopheles
           gambiae str. PEST
          Length = 183

 Score =  119 bits (287), Expect = 6e-26
 Identities = 67/183 (36%), Positives = 96/183 (52%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           K+KV  +TGAATG+G +    LL  G K + I D+  +AG+    EL  +YG +  F   
Sbjct: 4   KNKVALVTGAATGLGRAFSEELLKHGAK-VVICDLDSDAGELTVEELEKQYGARVLFCHC 62

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 383
           DVTD   F       V     +++VINNA +MND+   ++  ++VN+   I  TL A + 
Sbjct: 63  DVTDYIQFEEAFEYTVNMFKEVNIVINNAEIMNDNF--WELEVDVNLNGAIRGTLLAQKF 120

Query: 384 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 563
           M K  G  GG ++N+ S  ++T     PIY ATK A+L  +   G P H + T VR    
Sbjct: 121 MDKSKGKGGGVLVNIGSGVSVTPQLSTPIYTATKHAILGLTKACGDPFHHANTNVRAFAY 180

Query: 564 CFG 572
           C G
Sbjct: 181 CPG 183


>UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to
           hydroxyprostaglandin dehydrogenase 15 (NAD); n=2;
           Tribolium castaneum|Rep: PREDICTED: similar to
           hydroxyprostaglandin dehydrogenase 15 (NAD) - Tribolium
           castaneum
          Length = 479

 Score =  119 bits (286), Expect = 7e-26
 Identities = 62/199 (31%), Positives = 109/199 (54%), Gaps = 2/199 (1%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-K 185
           M  +  +KV  I+GAA+GIG ++ + LL  G++ + I D+ +E G+    E+ +++G+ +
Sbjct: 1   MPFDINNKVALISGAASGIGLTIAKELLRNGLRGVTIADVNKELGEKALQEIENEFGSGR 60

Query: 186 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 365
             F  +DV+  + F       +     ID+++N A ++NDSI  +++ I +NV   +   
Sbjct: 61  AIFVLTDVSSMKSFEDAFQKTINTFKNIDILVNGAGVLNDSI--WQQEIAINVNGTVHGI 118

Query: 366 LKAIE-IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
           L A+E  + K+     G ++N SS+A +      PIY  TK A+   +   G   H+ +T
Sbjct: 119 LLALENYIPKYKTDSEGVIVNFSSIAGVAAFPAFPIYTGTKFAIFGMTKAFGDEAHYERT 178

Query: 543 GVRVLTVCFGATDTALLTD 599
            VR++ +C G TDT LL D
Sbjct: 179 KVRIMAICPGPTDTPLLRD 197



 Score = 93.5 bits (222), Expect = 4e-18
 Identities = 52/172 (30%), Positives = 91/172 (52%), Gaps = 2/172 (1%)
 Frame = +3

Query: 75  VVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDVTDEEHFLGILNAVV 251
           +VR     G   + I DI  E G+ +  E+ +++G NK  +  +DVT +  +       +
Sbjct: 233 IVRNAPSGGAWGVTIADINTELGEKVLQEIINEFGKNKAIYILTDVTCKNSYEAAFKKTI 292

Query: 252 QEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE-IMGKHSGGKGGTVINV 428
           +    +D+V+N A ++N+    +++ +++N+   +  T+ A+E  + K+  G  G ++N+
Sbjct: 293 ETFQNLDIVVNGAGIVNELD--WQQEVDINLNGTLHGTILALENYIPKYKSGSEGVIVNI 350

Query: 429 SSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCFGATDT 584
           SS A L      PIY  TK AV+  S   G   H+ +T VRVLT C G T+T
Sbjct: 351 SSAAILDCFPPYPIYTGTKFAVMGISKSFGAEVHYKRTKVRVLTACPGVTET 402


>UniRef50_UPI0000D57365 Cluster: PREDICTED: similar to CG4899-PA,
           isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG4899-PA, isoform A - Tribolium castaneum
          Length = 295

 Score =  114 bits (274), Expect = 2e-24
 Identities = 64/191 (33%), Positives = 97/191 (50%), Gaps = 1/191 (0%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 206
           KV  ITG + GIG +V   +L E  K++A++ +    G+     LNS YG NK  F+  D
Sbjct: 52  KVALITGGSDGIGLAVAHEILSENSKNVALIGVDNTKGRESVHALNSTYGRNKAVFFNCD 111

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 386
           V  +       N V++E G ID+VIN A + +     ++K I  N+   I  TL+A  +M
Sbjct: 112 VESKVQVNDCFNKVIKEFGSIDIVINAAGVFDGRC--WEKEIMTNLVGTIHCTLEAYRVM 169

Query: 387 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 566
            K   G GG ++N S +  +      P   A+   ++  S   G   +F  TGVRV+T+C
Sbjct: 170 SKDCSGSGGVILNFSGLHGVKPLFPAPTLSASFHGIIGLSRSFGHETNFKTTGVRVVTLC 229

Query: 567 FGATDTALLTD 599
            G T+T  + D
Sbjct: 230 PGITNTNFIKD 240


>UniRef50_UPI00015B572C Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=2; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 268

 Score =  108 bits (260), Expect = 1e-22
 Identities = 70/219 (31%), Positives = 116/219 (52%), Gaps = 5/219 (2%)
 Frame = +3

Query: 27  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIA----EEAGKSLQVELNSKYG-NKTK 191
           +KV  +TG   GIG  +V+  L  G K +AI D+     EE   +L+ +L  ++   +  
Sbjct: 5   NKVGVVTGGLRGIGYVIVQHFLRRGAKFVAIFDLDVEEHEEVVNALK-QLEQEFAAQRFS 63

Query: 192 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 371
           +Y  DVT+ + F+   + V    G +D+++NNA +  +        + VN T++I  T+ 
Sbjct: 64  YYCCDVTNFKKFIACYDEVYTTNGAVDILVNNAGVFAEHD--QDLTVAVNFTSVIHCTMH 121

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           AIE MG + GGKGG ++ + S+ AL     +P+Y ATK A+  F       ++ +K GVR
Sbjct: 122 AIERMGTNKGGKGGVIVTIGSICALISLSTIPVYSATKGALACFVR--STKDYNAKYGVR 179

Query: 552 VLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKKGFI 668
           ++ +C G T T      K+    K ++S CLD + + FI
Sbjct: 180 IVCLCPGMTKT------KMTHAVKAIKSYCLDFVPQKFI 212


>UniRef50_Q9I7R3 Cluster: CG18814-PA; n=3; Sophophora|Rep:
           CG18814-PA - Drosophila melanogaster (Fruit fly)
          Length = 285

 Score =  103 bits (248), Expect = 3e-21
 Identities = 69/217 (31%), Positives = 113/217 (52%), Gaps = 18/217 (8%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS-D 206
           K V   G   GIG+  V+ LL + +K +AI D+  +    L  E   ++ +   FY+  D
Sbjct: 6   KNVVYLGGFGGIGKKCVQELLKKQIKGLAIFDLIVD--DDLLAEWKKQHPDTEIFYQKMD 63

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMND-----SIGIYKKAIEVNVT-------- 347
           +T +        A  ++ G  DVV+N + L++D     +I I    +E+ ++        
Sbjct: 64  ITQKSDIDAAYKATAEKLGHFDVVVNGSGLLDDRRIELTIQINLVILEIVLSKGFIYQYF 123

Query: 348 ---ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 518
               +I STL A+E M K  GG+GG ++N+SSVA L  + +M IY  +K+ V  F+  + 
Sbjct: 124 LKVGVINSTLTALEYMDKSKGGRGGLIVNISSVAGLQPTPLMAIYSTSKTGVTTFTRAMA 183

Query: 519 RPEHFSKTGVRVLTVCFGATDTALLTD-EKLGTFDKY 626
            P H++ +GV  +T+C G T+T +L D +K  TF  Y
Sbjct: 184 SPIHYAHSGVGFITICPGYTNTGILKDIDKKTTFPFY 220


>UniRef50_UPI0000D5767E Cluster: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase; n=2; Tribolium
           castaneum|Rep: PREDICTED: similar to
           15-hydroxyprostaglandin dehydrogenase - Tribolium
           castaneum
          Length = 255

 Score =  102 bits (245), Expect = 7e-21
 Identities = 60/192 (31%), Positives = 103/192 (53%), Gaps = 1/192 (0%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
           E K KV  +TG A+GIG ++VR LL  G+K ++++DI+E        EL     ++  F 
Sbjct: 3   ELKGKVALVTGGASGIGLAMVRELLKNGIKAVSVVDISENT------ELQD---SRVTFI 53

Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 377
           ++DVT ++      +  V     +D+V+NNA ++ D I  +K+ I++N+ A+I  T  A+
Sbjct: 54  KTDVTCKKQLQAAFDKTVATYNQLDIVVNNAGVI-DEID-WKRTIDINLVAVIEGTYLAL 111

Query: 378 EI-MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
              + K+     G ++N +SV  L      PIY  +K  V+     +G P  + +  VR+
Sbjct: 112 RTYLPKYKSEAEGVIVNTASVLGLCPLQSAPIYCTSKHGVVGLGRSLGGPHIYDEYKVRI 171

Query: 555 LTVCFGATDTAL 590
           +T+C G  DT +
Sbjct: 172 VTICPGLVDTPM 183


>UniRef50_Q5P8S6 Cluster: Putative dehydrogenase; n=4;
           Proteobacteria|Rep: Putative dehydrogenase - Azoarcus
           sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1))
          Length = 267

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 67/211 (31%), Positives = 106/211 (50%), Gaps = 10/211 (4%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           M      KV +++GAA+GIG ++ R+   EG   + + D+  E G+++   +  + G + 
Sbjct: 1   MKQNLSGKVAYVSGAASGIGAAIARVFAAEGAS-VLLGDVQVERGETVAAHIREQ-GGRA 58

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTA 350
            F   DV+DE  +   L   V+E GG+D+++NNA       L +  +    K + VNV  
Sbjct: 59  LFIHHDVSDERQWESALACAVEEFGGMDLLVNNAGIEQTGLLADVELADINKLLAVNVAG 118

Query: 351 LITSTLKAIEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527
           +I     AI  M    S GKGG++IN+SSVA L  +  + +Y ATK AV   S       
Sbjct: 119 VILGHKHAIRTMRPGGSAGKGGSIINLSSVAGLIGTPALGVYSATKGAVRLLSKAAAVEC 178

Query: 528 HFSKTGVRVLTVCFGATDTAL---LTDEKLG 611
                G+RV ++  G  DT +   L D+ +G
Sbjct: 179 GRLGYGIRVNSIHPGLVDTDMGVKLVDDFVG 209


>UniRef50_A6YPS8 Cluster: Oxidoreductase; n=1; Triatoma
           infestans|Rep: Oxidoreductase - Triatoma infestans
           (Assassin bug)
          Length = 252

 Score = 95.9 bits (228), Expect = 8e-19
 Identities = 66/196 (33%), Positives = 105/196 (53%), Gaps = 8/196 (4%)
 Frame = +3

Query: 21  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
           WKD+V  +TGA+ GIGE++ R L + G+K +A L    +  + LQ + N+  G+  K Y+
Sbjct: 4   WKDRVAVVTGASAGIGEAIARALAEHGMK-VAALARRLDRLQKLQDDCNNFIGS-IKPYK 61

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-----MND-SIGIYKKAIEVNVTALITS 362
            DVT+E      + ++V + G I V++NNA L     M D S G  ++  E NV  L+T 
Sbjct: 62  CDVTNETEIATTIKSIVSDLGPISVLVNNAGLYENVPMTDTSQGSCRQTYETNVIGLVTF 121

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVA--ALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
           T   +EIM KH+    G +IN++S+A   +     M  Y A+K AV   +  +       
Sbjct: 122 TQHVVEIMKKHN-ITDGHIININSLAGHVIIPKPGMANYTASKHAVTVLTESLKNELAAM 180

Query: 537 KTGVRVLTVCFGATDT 584
           K+ +RV ++  G  +T
Sbjct: 181 KSKIRVTSISPGLVNT 196


>UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=10; Mycobacterium|Rep: Short-chain
           dehydrogenase/reductase SDR - Mycobacterium sp. (strain
           JLS)
          Length = 282

 Score = 95.5 bits (227), Expect = 1e-18
 Identities = 60/213 (28%), Positives = 107/213 (50%), Gaps = 8/213 (3%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
           E + +V  +TG A+GIG  V    + EG K + I D+ +E G++L  +     G    F+
Sbjct: 8   ELQGRVAIVTGGASGIGRGVAERFVAEGAK-VVIADVQDELGEALAEQC----GPNALFH 62

Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA--------LMNDSIGIYKKAIEVNVTAL 353
            +DV D+E    +++  V+  G +DV++NNA         L N+ +  + + + VN+ ++
Sbjct: 63  HTDVGDQEQMRRLVDVAVERFGALDVMVNNAGISSPLRRGLFNEDLEEFDRVMRVNLLSV 122

Query: 354 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533
           +  T  A   M +H GG   ++IN+SS+  +     +P+Y A+K+A+L F+ C       
Sbjct: 123 MAGTRDAGRYMSEHGGG---SIINLSSIGGIQAGGGVPVYRASKAAILHFTKCAA--IEL 177

Query: 534 SKTGVRVLTVCFGATDTALLTDEKLGTFDKYLE 632
           +   +RV  +  G   T +L     G   + LE
Sbjct: 178 AHYDIRVNCIAPGNIPTPILQSSATGEDRERLE 210


>UniRef50_Q9NAR7 Cluster: Alcohol dehydrogenase; n=23;
           Schizophora|Rep: Alcohol dehydrogenase - Bactrocera
           oleae (Olive fruit fly)
          Length = 258

 Score = 95.1 bits (226), Expect = 1e-18
 Identities = 59/188 (31%), Positives = 100/188 (53%), Gaps = 2/188 (1%)
 Frame = +3

Query: 33  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--KSLQVELNSKYGNKTKFYRSD 206
           VVF+ G    IG    + ++ + V    + D+ E A   K+LQ  +N K   K  + + D
Sbjct: 8   VVFVGGLGF-IGYEACKQIMTKNVASFFVFDVLENAENIKALQA-INPK--TKVYYTKFD 63

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 386
           +T++         V+ +   IDV++N A ++ D     +  + +N+  LI +TL+AI +M
Sbjct: 64  ITNKASIKSAFADVIAKVQYIDVLVNGAGILTDPN--VELTMNINLIGLINTTLEAIPLM 121

Query: 387 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 566
            K+  G+GG ++N++SV  L  +    IY A+K  V+ FS  I  P +++ TG+ V T C
Sbjct: 122 DKNKKGRGGLIVNIASVLGLEPAPPAAIYCASKFGVMGFSRSISDPYYYNLTGIAVATFC 181

Query: 567 FGATDTAL 590
            G T+T L
Sbjct: 182 PGLTETPL 189


>UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1;
           Planctomyces maris DSM 8797|Rep: Probable putative
           oxidoreductase - Planctomyces maris DSM 8797
          Length = 270

 Score = 93.5 bits (222), Expect = 4e-18
 Identities = 61/196 (31%), Positives = 96/196 (48%), Gaps = 3/196 (1%)
 Frame = +3

Query: 21  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
           ++D+VV +TG + GIGE   R+   EG  H+AIL     AG+ L  ELN     K  F +
Sbjct: 18  FQDRVVIVTGGSKGIGEGCSRVFCAEG-GHVAILARGLHAGQDLARELNETGPGKAMFVQ 76

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTAL---ITSTLK 371
            DV + E     ++ VV++ G +D +INNA +   ++ + + +IE     +     ST  
Sbjct: 77  CDVGEHEQIRSAIDLVVEQFGRLDCIINNAGVHPPAMSLEETSIEEMEQLMRVNFLSTFA 136

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
             +    H     GT+IN+SS+ A+   H    Y +TK A + F+  +       + GVR
Sbjct: 137 GAKYALPHLRKTKGTIINMSSMTAVLGQHHSTAYCSTKGAQVSFTKSLA--IELGEAGVR 194

Query: 552 VLTVCFGATDTALLTD 599
           V  +     DT L+ D
Sbjct: 195 VNAILPSNIDTPLMRD 210


>UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 266

 Score = 93.5 bits (222), Expect = 4e-18
 Identities = 61/194 (31%), Positives = 99/194 (51%), Gaps = 7/194 (3%)
 Frame = +3

Query: 33  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 209
           V  +TG   GIG ++ + LLD   K + +LDI E+ G      L+  Y  ++  F + DV
Sbjct: 7   VAIVTGGVQGIGLAISKALLDRDGK-VCMLDINEKTGNETLKLLSENYSKHRVLFIKCDV 65

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALM---NDSI--GIYKKAIEVNVTALITSTLKA 374
           T +              G +D++ NNA +    ND +  G +K  I++NV  +I  TL  
Sbjct: 66  TSQPQMEAAFQRTKDVFGRLDILCNNAGIAVRENDLLRSGAWKTIIDINVKGVILGTLLG 125

Query: 375 IEIMGKHSG-GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           ++ MG     G GGT++NV+S+A L  +   P+Y A+K AV+  +  +     ++   VR
Sbjct: 126 LDHMGVSGAKGHGGTIVNVASLAGLVPAPASPVYTASKHAVVGLTRTL--TSLWATECVR 183

Query: 552 VLTVCFGATDTALL 593
           V  +C   TDTA++
Sbjct: 184 VNCICPSFTDTAMV 197


>UniRef50_Q9ABI1 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=7; Alphaproteobacteria|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Caulobacter crescentus (Caulobacter vibrioides)
          Length = 261

 Score = 92.7 bits (220), Expect = 7e-18
 Identities = 57/169 (33%), Positives = 91/169 (53%), Gaps = 7/169 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-YRSD 206
           K  FITG A G+G +  R+L  EG K +A+ DI     +++  E+N+ +G  T F +  D
Sbjct: 11  KKAFITGGAQGLGAAAGRMLAKEGAK-VALADINLAGAQAVADEINAAHGAGTAFAFELD 69

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTL 368
           VT E+ ++ +L       GG+ V++NNA +  D        G++KK + VNV ++     
Sbjct: 70  VTQEDQWIDVLEKATAAMGGLSVLVNNAGIGGDGPIESLDFGLWKKVMSVNVDSVFLGAK 129

Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 515
            A+  M  H   + G++IN+SS+A L  +   P Y A+K+AV   S  I
Sbjct: 130 HALTHMRAH---QPGSIINLSSIAGLIANGNSPAYNASKAAVWLLSKNI 175


>UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase family
           protein; n=4; cellular organisms|Rep: Short-chain
           dehydrogenase/reductase family protein - Gramella
           forsetii (strain KT0803)
          Length = 249

 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 66/204 (32%), Positives = 104/204 (50%), Gaps = 9/204 (4%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           K K + ITGA++GIGE+    L  EGV ++ +    EE  K L+ +++ + G K      
Sbjct: 4   KGKTIIITGASSGIGEATAMRLAKEGV-NVVLTARREEKLKELKSKIDKENGGKALVIPG 62

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITST 365
           DVT +E F  +++   +E G ID +INNA LM      N     + K ++VN+  ++   
Sbjct: 63  DVTKKEDFKNLIDKTKKEFGSIDGLINNAGLMPLSYVKNLHTDEWDKMVDVNIKGVLNGV 122

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
              +  M +    K G +IN+SS AA        +Y ATKSAV  FS  + R E   K  
Sbjct: 123 AAVLPTMMEQ---KSGNIINISSSAARKIYPGGAVYCATKSAVKMFSEGL-RQELAPKFN 178

Query: 546 VRVLTVCFGATDTAL---LTDEKL 608
           + + ++  G  DT L   +TD+++
Sbjct: 179 INITSIEPGFVDTELTDTITDDEI 202


>UniRef50_Q6C6W8 Cluster: Similar to tr|Q9WYD3 Thermotoga maritima
           TM0297 Oxidoreductase; n=7; Ascomycota|Rep: Similar to
           tr|Q9WYD3 Thermotoga maritima TM0297 Oxidoreductase -
           Yarrowia lipolytica (Candida lipolytica)
          Length = 291

 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 61/195 (31%), Positives = 102/195 (52%), Gaps = 8/195 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  +TG A G+G S+   L   G+K IAILD+ ++ G     +L+  YG + +FY++DV
Sbjct: 46  KVAIVTGGARGLGFSMAEGLCSVGLKGIAILDVQQDLGLDAIEKLHKAYGVQAQFYKADV 105

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 371
            DEE    I++ VV + G +DVV+N+A + +           +++ I++N+      T  
Sbjct: 106 RDEESVNEIIDRVVHDLGSVDVVVNSAGVADLVHAAEYPADKFRRVIDINLNGSFLVTQA 165

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMP--IYFATKSAVLQFSNCIGRPEHFSKTG 545
           A   M K   G GGTV+ ++S++    +   P   Y A+K+AV   S  +     ++   
Sbjct: 166 AARHMIKQ--GTGGTVVFIASMSGSIVNWPQPQSAYNASKAAVKHLSKSLA--AEWAVHN 221

Query: 546 VRVLTVCFGATDTAL 590
           +R  ++  G  DTAL
Sbjct: 222 IRCNSISPGYMDTAL 236


>UniRef50_Q5TWK5 Cluster: ENSANGP00000025423; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000025423 - Anopheles gambiae
           str. PEST
          Length = 191

 Score = 89.4 bits (212), Expect = 7e-17
 Identities = 58/195 (29%), Positives = 99/195 (50%), Gaps = 1/195 (0%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           MS   +  VVF  G   G+G ++ + LL +GVK + I+D+ E    +L     S      
Sbjct: 1   MSLAGQSAVVF--GGCGGMGMAIGQHLLRQGVKKLCIVDVVELTDSNLSCLKESGRDALI 58

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQ-GGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 365
                D+++      +L   + E  G ID+++N+A ++   +    K I    T +I S 
Sbjct: 59  LCKICDISNRAALKQLLERDISEALGSIDILVNSAGIVESEVP--DKLIG---TGVINSC 113

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
           L A+ +M +  GGKGG ++NV+S A L     +P Y A+K  ++ F+  +G    +S+TG
Sbjct: 114 LIALNLMSRAKGGKGGVIVNVASTAGLEPIPFLPTYCASKHGLIGFTRSLGVEPVYSETG 173

Query: 546 VRVLTVCFGATDTAL 590
           V+ + +C G T T +
Sbjct: 174 VKFIIICPGGTRTRM 188


>UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Methanospirillum hungatei JF-1|Rep: Short-chain
           dehydrogenase/reductase SDR - Methanospirillum hungatei
           (strain JF-1 / DSM 864)
          Length = 249

 Score = 89.0 bits (211), Expect = 9e-17
 Identities = 57/200 (28%), Positives = 103/200 (51%), Gaps = 6/200 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           ++KV+ +TG + GIG+++     DEG K +   +  EE+ K++  E++ K G+     ++
Sbjct: 6   ENKVLLVTGGSRGIGKAIALRCADEGAKVVITWESHEESAKNVVNEIHHKNGSAMAI-QA 64

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE------VNVTALITST 365
           DV +E+    ++N +  E G +D+++NNA +M +++ +  K  E       N       +
Sbjct: 65  DVRNEDDVKKVINKIKGEYGRLDILVNNAGIMKNNLLLMTKTEEFDLLLATNCKGPFLYS 124

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
             A ++M KH   K G +IN+SSV  +  S    +Y ATKS ++ F+  + +       G
Sbjct: 125 RAAAKLMLKH---KSGRIINISSVVGVYGSKGQSVYSATKSFLIAFTKSLAK--ELGPFG 179

Query: 546 VRVLTVCFGATDTALLTDEK 605
           + V  +  G  DT L  D K
Sbjct: 180 ITVNAIAPGFIDTDLTHDVK 199


>UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep:
           Oxidoreductase - Oceanobacillus iheyensis
          Length = 244

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 58/198 (29%), Positives = 100/198 (50%), Gaps = 6/198 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           +DKV  ITG  +GIG +  ++   EG K I ++D+ EE G S++ EL S+ G++  F ++
Sbjct: 4   QDKVAVITGGVSGIGAATAKLFASEGAKLI-LVDMNEEKGASIEAELKSQ-GSEAIFIKA 61

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 365
           DVT+EE    I    +   G +D++ NNA +         +   ++K +EV++  +    
Sbjct: 62  DVTNEEQVKNIYTTAIDTFGKVDILFNNAGIGAVKPTEELTYAEWRKTVEVDLDGVFLVA 121

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
             AI+   K      G ++N +S+     S     Y A K+ V+  +  +G    ++   
Sbjct: 122 QAAIKEFLK---AGSGVIVNTASMYGWVGSPGSAAYNAAKAGVVNLTRSLGL--EYAARN 176

Query: 546 VRVLTVCFGATDTALLTD 599
           +RV  +C G  DTA+L D
Sbjct: 177 IRVNALCPGFIDTAILGD 194


>UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family; n=16; Bacillaceae|Rep:
           Oxidoreductase, short-chain dehydrogenase/reductase
           family - Bacillus anthracis
          Length = 264

 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 66/212 (31%), Positives = 107/212 (50%), Gaps = 7/212 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           M+   ++KV+ ITGA++GIGE V   + ++G   + ++   EE  K+L  ++   Y    
Sbjct: 1   MTGRLQNKVIVITGASSGIGEQVAMQVAEQGATPV-LMARTEEKLKALADKIKETYNTPC 59

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 350
            +Y  DV++E     + + V+QE G ID+++NNA         + S+   K   +VNV  
Sbjct: 60  YYYVLDVSEETEVQSVFSKVLQEVGRIDILVNNAGFGIFKTFEDASMDEVKDMFQVNVFG 119

Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
           L+  T   +  M K + G    +IN++S+A    +     Y ATK AVL F+N + R E 
Sbjct: 120 LVACTKAVLPYMVKRNEGH---IINIASLAGKIATPKSSAYAATKHAVLGFTNSL-RME- 174

Query: 531 FSKTGVRVLTVCFGATDTALL-TDEKLGTFDK 623
            S T V V  +  G  DT      ++ GT+ K
Sbjct: 175 LSSTNVFVTAINPGPIDTNFFEIADQSGTYVK 206


>UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=3; cellular organisms|Rep:
           3-oxoacyl-[acyl-carrier protein] reductase - Pyrococcus
           furiosus
          Length = 260

 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 59/201 (29%), Positives = 102/201 (50%), Gaps = 6/201 (2%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           K+KV  +TG   GIG ++ ++  + G K + + +I EEAG   +  L  + G    F ++
Sbjct: 7   KNKVAIVTGGGQGIGAAIAQLFAENGAK-VVLAEIDEEAGLEREAMLRER-GLDVTFIKT 64

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITST 365
           DV DEE    ++   V+  GG+D+++NNAA+M+       ++  +++ I VN+T     +
Sbjct: 65  DVADEESVKNMVKKTVELYGGVDILVNNAAIMSVKSIFERTLEEWERVIRVNLTGPYICS 124

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
             A E M K     GG +IN++S  AL        Y A+K  +L  ++ +      +K  
Sbjct: 125 RYAAEEMIKRG---GGVIINIASTRALMSEPDTEPYSASKGGLLALTHSLA--ISLAKYR 179

Query: 546 VRVLTVCFGATDTALLTDEKL 608
           +RV+ V  G  +T+     KL
Sbjct: 180 IRVVAVSPGWIETSRWKKSKL 200


>UniRef50_Q89M15 Cluster: Dehydrogenase; n=3; Proteobacteria|Rep:
           Dehydrogenase - Bradyrhizobium japonicum
          Length = 271

 Score = 87.4 bits (207), Expect = 3e-16
 Identities = 58/203 (28%), Positives = 105/203 (51%), Gaps = 7/203 (3%)
 Frame = +3

Query: 3   LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN 182
           + M+ + + KV  +TG A+GIGE++V +   EG   IA  D+ E  G  L   + +K G 
Sbjct: 1   MNMAGQVEGKVALVTGGASGIGEAIVELFAREGATVIA-TDVDELRGPELAKRI-TKAGG 58

Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA-------ALMNDSIGIYKKAIEVN 341
           K  F   DV+ EE ++ I+  + +  G +D++++NA       ++++ ++G ++K   +N
Sbjct: 59  KAIFLEQDVSSEERWIEIVAEIAKRYGRLDIMVSNAGIGIAVPSIVDMTLGDWRKQNAIN 118

Query: 342 VTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 521
           +  +  S    + +M K     GG+++ +SS+A L  +  +  Y ATK  V  F+  I  
Sbjct: 119 LDGVFLSVKHCLPLMRKTG---GGSIVMMSSLAGLRGAPGLSAYSATKGGVRLFAKSIAM 175

Query: 522 PEHFSKTGVRVLTVCFGATDTAL 590
                  G+RV +V  G  DT +
Sbjct: 176 ECAAVGDGIRVNSVHPGIIDTPI 198


>UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Flavobacterium johnsoniae UW101|Rep: Short-chain
           dehydrogenase/reductase SDR - Flavobacterium johnsoniae
           UW101
          Length = 269

 Score = 87.4 bits (207), Expect = 3e-16
 Identities = 61/190 (32%), Positives = 100/190 (52%), Gaps = 6/190 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKY-GNKTKFYR 200
           KDK + ITG  TGIG+++  +L+  G + + I    E+  K+   ++  ++ G++     
Sbjct: 30  KDKKIVITGGTTGIGKAIADVLVSLGGR-VLIFGRDEKDFKNAVADIQKQFPGSEVYGTP 88

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-----MNDSIGIYKKAIEVNVTALITST 365
           +DVT +E    IL     E GGID++INNAAL      N+S   YK  I+ N+T  +   
Sbjct: 89  ADVTKKEDIQKILEIADNELGGIDILINNAALGAPGITNESYDDYKYIIDTNITGYLAFA 148

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
            +A   M +    K G +IN+ S++A ++     IY ATKSA+  FS  + +    +  G
Sbjct: 149 QEAASRMKQQ---KSGHIINIGSMSAESKEAKSTIYVATKSAIRGFSTSLRK--ELNPLG 203

Query: 546 VRVLTVCFGA 575
           ++V  +  GA
Sbjct: 204 IKVSLIEPGA 213


>UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reductase;
           n=7; Bacteria|Rep: 3-ketoacyl-acyl carrier protein
           reductase - Leptospira interrogans
          Length = 254

 Score = 87.0 bits (206), Expect = 4e-16
 Identities = 60/203 (29%), Positives = 100/203 (49%), Gaps = 6/203 (2%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           K K   +TGAA GIG+S    L   G  ++ I D+ EE+ K+   E++ + G K     +
Sbjct: 5   KGKNAVVTGAARGIGKSTALTLAKAGA-NLVIADLNEESSKATADEISKQTGVKAIGIGT 63

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK------AIEVNVTALITST 365
           +V+D +     + A V E G +D+++NNA +  D++ +  K       I VN+T     T
Sbjct: 64  NVSDVDSAAKAIQACVDEFGSVDILVNNAGITKDTLLMRMKKEQWDAVIAVNLTGTFNCT 123

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
             AI+ M K+    GG++IN+SS+A +  +     Y A+K+ V+ F+  +       K  
Sbjct: 124 QAAIKFMMKNP--NGGSIINLSSIAGVNGNIGQTNYSASKAGVIGFTKAVALEMASRKVR 181

Query: 546 VRVLTVCFGATDTALLTDEKLGT 614
              +   F AT+      EK+ T
Sbjct: 182 CNAIAPGFIATEMTDAIPEKIRT 204


>UniRef50_Q2W431 Cluster: Dehydrogenase with different
           specificities; n=2; Magnetospirillum|Rep: Dehydrogenase
           with different specificities - Magnetospirillum
           magneticum (strain AMB-1 / ATCC 700264)
          Length = 248

 Score = 87.0 bits (206), Expect = 4e-16
 Identities = 65/212 (30%), Positives = 105/212 (49%), Gaps = 6/212 (2%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
           +++DKV  ITG A+GIG   V+ + + G   + I DI  EAG+    EL +K G K +F 
Sbjct: 2   KFEDKVALITGGASGIGYCTVKSMAELGA-DVLIADINVEAGEKAAAELTAK-GFKAEFV 59

Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALIT 359
           R DVTD+ +   +   VV  +G +D++ N A        +++      K + +N+T  I 
Sbjct: 60  RLDVTDKANIARVKEHVVATRGRLDILCNVAGWGHIQPFVDNDDAFIAKVMSLNLTGPIE 119

Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
                  +M +   GK   ++NV+S A    S    +Y A K  ++ FS  + R    ++
Sbjct: 120 LIRAFFPLMIEKKTGK---IVNVASDAGRVGSLGESVYSAAKGGLIAFSKALAR--EGAR 174

Query: 540 TGVRVLTVCFGATDTALLTDEKLGTFDKYLES 635
             + V  +C G TDT LL  E     +K+LE+
Sbjct: 175 FNINVNAICPGPTDTPLLKSEP----EKFLEA 202


>UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillus
           sp. B14905|Rep: Short chain dehydrogenase - Bacillus sp.
           B14905
          Length = 252

 Score = 86.6 bits (205), Expect = 5e-16
 Identities = 57/198 (28%), Positives = 97/198 (48%), Gaps = 7/198 (3%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
           E  +K+  +TGA +GIG +    L   G K + I+D  +E G+   ++L  + G +  F 
Sbjct: 2   EHLNKIAVVTGAGSGIGRASSLKLASNGAK-VVIVDFNKETGEET-LKLVKEQGGEGIFV 59

Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALI 356
           ++DV+  E     +NA V+  G IDV  NNA ++     +       Y + + +NV  + 
Sbjct: 60  QADVSKSEDVEKYVNAAVETYGRIDVFFNNAGVIQKISPLTEIADSEYDRIMSINVKGVF 119

Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
                 I++M    G   G++IN +S A +   H M +Y A+K AV+  +        + 
Sbjct: 120 LGLKHVIKVM---EGQGSGSIINTASTAGVRSEHSMAVYSASKHAVIGLTKSASL--EYV 174

Query: 537 KTGVRVLTVCFGATDTAL 590
           K G+R+  +C G  +TAL
Sbjct: 175 KKGIRINAICPGGVETAL 192


>UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=2; Actinomycetales|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Mycobacterium avium (strain 104)
          Length = 250

 Score = 86.2 bits (204), Expect = 6e-16
 Identities = 56/189 (29%), Positives = 101/189 (53%), Gaps = 4/189 (2%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  +TGAA+GIGE+  + L ++G K + + DI E+ G+ +  E+ ++ G +  F R+D+
Sbjct: 6   KVAVVTGAASGIGEATAKRLAEDGAK-VVVADINEDGGERVVAEI-AERGGEAAFLRTDI 63

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEV--NVTAL-ITSTLKAIE 380
           + EE    +++  V   GG+ +  NNAA+ +    +++ + +V   VT + +  T   + 
Sbjct: 64  SIEEDVNSLIDFAVSTYGGLHLAHNNAAVAHTPTPLHELSTDVFDTVTGIGLRGTFFCMR 123

Query: 381 IMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
               H  G  GG ++N +S AAL  +  M  Y ATK  ++  +   G    +++ G+RV 
Sbjct: 124 AEIAHMIGHGGGAIVNTASGAALKAAAGMHAYVATKHGIVGLTRNAGL--DYARNGIRVN 181

Query: 558 TVCFGATDT 584
            V  G+  T
Sbjct: 182 AVAPGSIKT 190


>UniRef50_Q6XPZ7 Cluster: Short-chain dehydrogenase/reductase; n=1;
           Apis mellifera|Rep: Short-chain dehydrogenase/reductase
           - Apis mellifera (Honeybee)
          Length = 246

 Score = 85.8 bits (203), Expect = 8e-16
 Identities = 53/194 (27%), Positives = 102/194 (52%), Gaps = 9/194 (4%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           M   W D+V  +TGA +GIG+ ++  L+ +G+K I I    ++  K+L  EL SK G K 
Sbjct: 1   MEQNWIDEVALVTGANSGIGKCLIECLVGKGMKVIGIAPQVDKM-KTLVEELKSKPG-KL 58

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 350
              + D++++   L ++  V +  G ID++INNA       L ND +  +KK  ++N+  
Sbjct: 59  VPLQCDLSNQNDILKVIEWVEKNLGAIDILINNATINIDVTLQNDEVLDWKKIFDINLLG 118

Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALT---QSHVMPIYFATKSAVLQFSNCIGR 521
           L     + +++M K  G   G ++N++  + L     +   P Y A+K A+   ++C+  
Sbjct: 119 LTCMIQEVLKLM-KKKGINNGIIVNINDASGLNLLPMNRNRPAYLASKCALTTLTDCLRS 177

Query: 522 PEHFSKTGVRVLTV 563
                ++ ++V+++
Sbjct: 178 ELAQCESNIKVISI 191


>UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase
           bacC; n=5; Bacillus|Rep: Bacilysin biosynthesis
           oxidoreductase bacC - Bacillus subtilis
          Length = 253

 Score = 85.4 bits (202), Expect = 1e-15
 Identities = 61/194 (31%), Positives = 101/194 (52%), Gaps = 6/194 (3%)
 Frame = +3

Query: 27  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
           DK V ITG A+GIG + V+  L +   ++ + DI E  G+++  + N+   ++  F ++D
Sbjct: 5   DKTVLITGGASGIGYAAVQAFLGQQA-NVVVADIDEAQGEAMVRKENN---DRLHFVQTD 60

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTL 368
           +TDE      + + V   GG+DV+INNA       +    +  + K ++VN+T +   + 
Sbjct: 61  ITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSK 120

Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
            A++ M   + GK G +IN  SV  L     +P Y A+K  VLQ +  +     ++K  +
Sbjct: 121 HALKHM--LAAGK-GNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMA--VDYAKHQI 175

Query: 549 RVLTVCFGATDTAL 590
           RV  VC G  DT L
Sbjct: 176 RVNCVCPGIIDTPL 189


>UniRef50_P91615 Cluster: Alcohol dehydrogenase-related 31 kDa
           protein; n=44; Drosophiliti|Rep: Alcohol
           dehydrogenase-related 31 kDa protein - Drosophila
           melanogaster (Fruit fly)
          Length = 272

 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 58/201 (28%), Positives = 100/201 (49%), Gaps = 1/201 (0%)
 Frame = +3

Query: 60  GIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVT-DEEHFLGI 236
           GI     ++L+ + +  +AIL   E      Q++ + K   +  F+  DVT   E     
Sbjct: 17  GIALETSKVLMTKNIAKLAILQSTENPQAIAQLQ-SIKPSTQIFFWTYDVTMAREDMKKY 75

Query: 237 LNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKHSGGKGGT 416
            + V+ +   IDV+IN A L +++       I  N+T ++ +    +  M +  GG GG 
Sbjct: 76  FDEVMVQMDYIDVLINGATLCDENN--IDATINTNLTGMMNTVATVLPYMDRKMGGTGGL 133

Query: 417 VINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCFGATDTALLT 596
           ++NV+SV  L  S V   Y A+K  V+ F+  +  P ++S+ GV V+ VC G   T +  
Sbjct: 134 IVNVTSVIGLDPSPVFCAYSASKFGVIGFTRSLADPLYYSQNGVAVMAVCCG--PTRVFV 191

Query: 597 DEKLGTFDKYLESSCLDQLKK 659
           D +L  F +Y +S   D+L++
Sbjct: 192 DRELKAFLEYGQSFA-DRLRR 211


>UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Sphingomonadales|Rep: Short-chain
           dehydrogenase/reductase SDR - Sphingopyxis alaskensis
           (Sphingomonas alaskensis)
          Length = 285

 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 59/189 (31%), Positives = 90/189 (47%), Gaps = 4/189 (2%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  +TGAA+GIG++ V  L  EG  H+   DI E  G++L    N +      F R DV
Sbjct: 6   KVAVVTGAASGIGKATVLKLAGEGA-HVFAADIDEAGGRALADASNGRID----FVRCDV 60

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK---KAIEVNVTALITSTLKAIE 380
           T       +++A   + GGID+V NNAA   D   I +   +  +  +  ++ S    I 
Sbjct: 61  TVPSDIEALMDAAAAKAGGIDIVFNNAAAGGDRAPIDEITPEGWDATMDLVLKSVAMGIR 120

Query: 381 IMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
               H  G KG +++N +SVAAL   +    Y   K+ VL  +         ++ G+RV 
Sbjct: 121 YAAPHMKGRKGASIVNTASVAALGAGYSPTAYAVAKAGVLHLTRVAA--TDLAQYGIRVN 178

Query: 558 TVCFGATDT 584
            +C G  +T
Sbjct: 179 AICPGFINT 187


>UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Herpetosiphon aurantiacus ATCC
           23779|Rep: Short-chain dehydrogenase/reductase SDR
           precursor - Herpetosiphon aurantiacus ATCC 23779
          Length = 247

 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 57/195 (29%), Positives = 102/195 (52%), Gaps = 7/195 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  +TG A GIG +  ++L  +G   + I DI E+ G +   ++    G +  F   DV
Sbjct: 5   KVAIVTGGAIGIGAATAQLLAKQGAI-VVIGDINEQTGLATVEQIRGNAG-QAYFRHCDV 62

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALITSTL 368
           + E     ++   + +QGG+D++INNA +      ++       ++ +++++T +     
Sbjct: 63  SHEADIQALVQFAL-DQGGLDIMINNAGIGGKPAPLHLTENHNWQRVLDIDLTGVFWGQK 121

Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
            A + M   +GGKGG ++NV+S+A +  S  +  Y   K+ V+Q S   G  E  +  G+
Sbjct: 122 YASQAM--LAGGKGGAIVNVASIAGVAGSPNLGPYGVAKAGVIQMSK-TGAIE-LASAGI 177

Query: 549 RVLTVCFGATDTALL 593
           R+  VC G T+TA+L
Sbjct: 178 RINAVCPGWTETAIL 192


>UniRef50_Q89KQ8 Cluster: Blr4846 protein; n=2; Proteobacteria|Rep:
           Blr4846 protein - Bradyrhizobium japonicum
          Length = 255

 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 55/170 (32%), Positives = 87/170 (51%), Gaps = 5/170 (2%)
 Frame = +3

Query: 27  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
           D+VV ITG A+GIG + VR    +G + +A LDI E AG SL  E+ +  G    F R D
Sbjct: 11  DRVVLITGGASGIGAAFVRAFAAQGAR-VAFLDIDEAAGGSLVEEVAAASGAAPLFVRCD 69

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI--- 377
           + D +     +  V    G   V++NNAA  ND   +  +        +I   LK +   
Sbjct: 70  LLDIDALRAAIAQVRGSLGDAAVLVNNAA--NDQRQVLAEVTPSEFDWMIGVNLKHVFFA 127

Query: 378 --EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 521
              ++ +     GG++IN+SS+A +     +P+Y A K+A++ F+N + R
Sbjct: 128 AQAVVPQMQARGGGSIINMSSIAWMRGGPALPVYAAAKAAIVGFTNSLAR 177


>UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=4; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Burkholderia sp. (strain 383) (Burkholderia
           cepacia (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 251

 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 61/203 (30%), Positives = 98/203 (48%), Gaps = 6/203 (2%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  ITG A G GE+  R  + EG + + I D+ +EAG+ +  EL    G+  +F   DV
Sbjct: 7   KVALITGGARGQGEAEARRFVAEGAR-VVIADVLDEAGQRVAAEL----GDAARFQHLDV 61

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 371
           T E  +   ++A + + G +D+++NNAA++        S+  Y+K I+VN          
Sbjct: 62  TREADWQIAVDATLAQFGRLDILVNNAAILKLVPIEACSLDDYRKVIDVNQVGCWLGMKS 121

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           A   +G      GG+++NVSS A +        Y ++K AV   +        F + G+R
Sbjct: 122 A---LGALKAAGGGSIVNVSSTAGMEGVAGGSAYVSSKFAVRGMTKAAAL--EFGRYGIR 176

Query: 552 VLTVCFGATDTALLTDEKLGTFD 620
           V +V  G  DT +    +   FD
Sbjct: 177 VNSVHPGGIDTVMARPPEFADFD 199


>UniRef50_P00334 Cluster: Alcohol dehydrogenase; n=485;
           Drosophilidae|Rep: Alcohol dehydrogenase - Drosophila
           melanogaster (Fruit fly)
          Length = 256

 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 57/189 (30%), Positives = 93/189 (49%), Gaps = 2/189 (1%)
 Frame = +3

Query: 33  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVE-LNSKYGNKTKFYRSDV 209
           V+F+ G   GIG    + LL   +K++ ILD  E      +++ +N K      FY  DV
Sbjct: 10  VIFVAGLG-GIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKV--TVTFYPYDV 66

Query: 210 TDE-EHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 386
           T        +L  +  +   +DV+IN A +++D     ++ I VN T L+ +T   ++  
Sbjct: 67  TVPIAETTKLLKTIFAQLKTVDVLINGAGILDDHQ--IERTIAVNYTGLVNTTTAILDFW 124

Query: 387 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVC 566
            K  GG GG + N+ SV      + +P+Y  TK+AV+ F++ + +      TGV   TV 
Sbjct: 125 DKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPI--TGVTAYTVN 182

Query: 567 FGATDTALL 593
            G T T L+
Sbjct: 183 PGITRTTLV 191


>UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein)
           reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl carrier
           protein) reductase - Leptospira interrogans
          Length = 256

 Score = 82.6 bits (195), Expect = 8e-15
 Identities = 61/204 (29%), Positives = 101/204 (49%), Gaps = 7/204 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           M +  KDKV  +TG +TGIG++VV+  + +GVK +       E GK L+ E+ ++ G   
Sbjct: 1   MENIMKDKVAIVTGGSTGIGKAVVKEFVSKGVK-VVFCGRRLEEGKKLESEIRAE-GGDV 58

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSI-----GIYKKAIEVNVT 347
            F   DVT  E    +++A +++ G +D  INNA +M  N  +      ++ K + VN+ 
Sbjct: 59  YFVVCDVTSGEQVKKVVDAALEKFGRLDFGINNAGIMGLNHLLHEYPEDVWDKVVNVNLK 118

Query: 348 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527
               S    I  M K     GG V+NVSS++ +     +  Y A K  V+  +       
Sbjct: 119 GTWLSMKYQIPEMIKMG---GGVVVNVSSISGINGVVGINPYAAAKHGVVGLTKSAAL-- 173

Query: 528 HFSKTGVRVLTVCFGATDTALLTD 599
            ++K  +R+  +C GA  T +L +
Sbjct: 174 EYAKKNIRINAICPGAVKTEILDE 197


>UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1;
           Psychroflexus torquis ATCC 700755|Rep: 3-oxoacyl-[ACP]
           reductase - Psychroflexus torquis ATCC 700755
          Length = 251

 Score = 82.6 bits (195), Expect = 8e-15
 Identities = 63/193 (32%), Positives = 103/193 (53%), Gaps = 2/193 (1%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           M  + K K   ITG + GIG+S+   L +EGV +IAI    +EA +  + EL  K G K 
Sbjct: 1   MDLQLKGKNAIITGGSKGIGKSIALHLAEEGV-NIAICARGKEALQKTKNELLEK-GVKV 58

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITS 362
                DV D E F   L AV  E G +D+++NNA+   M D    ++ ++++++ A + +
Sbjct: 59  FTQTCDVGDSEQFNLFLTAVKNEFGSVDILVNNASALTMGDEYQDWEASLQIDLMASVRA 118

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
           T K +  M + SG   G ++ +SSV+ L +S   P Y A K+A++ +S  +      +  
Sbjct: 119 TKKVVPWMSE-SG--SGNILFISSVSGL-ESGSPPAYAAAKAALISYSKTMA--VQLAPQ 172

Query: 543 GVRVLTVCFGATD 581
            +RV T+  GA +
Sbjct: 173 HIRVNTIAPGAIE 185


>UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Caulobacter sp. K31|Rep: Short-chain
           dehydrogenase/reductase SDR - Caulobacter sp. K31
          Length = 277

 Score = 82.6 bits (195), Expect = 8e-15
 Identities = 56/193 (29%), Positives = 100/193 (51%), Gaps = 6/193 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K+  +TGAA G+G ++ +  L+EG   + + D++EE       EL +    +    R DV
Sbjct: 9   KIAIVTGAARGLGAAIAKRYLEEGAT-VVLADLSEEKTTERAAELGAGAHGR----RCDV 63

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 371
            D E F  +++A V E G +D+++NNA +         S+  +   + VNV+++      
Sbjct: 64  GDWEAFSTLIDATVAEFGRLDILVNNAGINRAGLVPGFSLQHWDDLLRVNVSSVFYGCRA 123

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           AI  M +  GG    +INV+S+A L    +   Y A+K+AV+ F+  +   +H +   +R
Sbjct: 124 AIPHMRRQGGG---AIINVASIAGLRGETLAAAYSASKAAVVNFTRSLAL-DH-ADENIR 178

Query: 552 VLTVCFGATDTAL 590
           V  +C G+ +T +
Sbjct: 179 VNAICPGSVETEM 191


>UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=6; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1
          Length = 260

 Score = 82.6 bits (195), Expect = 8e-15
 Identities = 59/206 (28%), Positives = 101/206 (49%), Gaps = 7/206 (3%)
 Frame = +3

Query: 27  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
           +K + ITG A+GIG +  ++L   G K I I D+AE+ G +L  +  +   +   F + D
Sbjct: 14  NKRILITGGASGIGAASAKLLASRGAK-IIIADLAEDLGHALAQQAWAS-DHTINFMKVD 71

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-------KAIEVNVTALITST 365
           VT       +    V++ GG+DVVINNA + +    +++       + + VNV  +    
Sbjct: 72  VTQAAEVNALFAYAVEQLGGLDVVINNAGVDHPPAPLHQLTEDDFDRCMTVNVKGVWHCM 131

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
             AI  +  H GG    VINV+S+A L  + ++  Y A+K AV+  +        +++  
Sbjct: 132 RAAIACLSPHGGGH---VINVASIAGLRSAPMLSAYSASKHAVIGLTK--SAAIEYARAN 186

Query: 546 VRVLTVCFGATDTALLTDEKLGTFDK 623
           +R   VC    DT ++ +  L   +K
Sbjct: 187 IRFNAVCPSFIDTPMVRNSMLNMNEK 212


>UniRef50_P54398 Cluster: Fat body protein 2; n=6; Schizophora|Rep:
           Fat body protein 2 - Drosophila melanogaster (Fruit fly)
          Length = 256

 Score = 82.6 bits (195), Expect = 8e-15
 Identities = 55/194 (28%), Positives = 97/194 (50%), Gaps = 2/194 (1%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE--EAGKSLQVELNSKYGNKTK 191
           +W  K V   G+ +GIG  ++  L+ + +K + I+   E  E  K LQ  +N     K  
Sbjct: 3   DWTGKNVVYVGSFSGIGWQMMMQLMQKDIKMMGIMHRMENVEMMKKLQA-INPSV--KVV 59

Query: 192 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 371
           F + ++ ++      +  + Q  G IDV+IN   ++ D     +  + +N+T +I ST+ 
Sbjct: 60  FMQMNLMEKMSIEQAMKKMGQMMGHIDVMINGEGVLLDKD--VETTMGMNLTGMIQSTMM 117

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           A+  M K   G GG V+N+SSV  L  +    +Y A    +L F+  +G    + KTGV 
Sbjct: 118 AMPYMDKTQMGMGGMVVNMSSVYGLEPAPAFAVYAAAMHGILGFTRSMGDKMIYQKTGVM 177

Query: 552 VLTVCFGATDTALL 593
            + +C G T++ ++
Sbjct: 178 FMAMCPGLTNSEMI 191


>UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=2; Bacteria|Rep:
           Oxidoreductase, short chain dehydrogenase/reductase
           family - Pseudomonas putida (strain KT2440)
          Length = 262

 Score = 82.2 bits (194), Expect = 1e-14
 Identities = 57/224 (25%), Positives = 105/224 (46%), Gaps = 7/224 (3%)
 Frame = +3

Query: 3   LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN 182
           + +++++  KVV +TGA +GIG +        G   +A+ DI+ + G    VEL    G 
Sbjct: 1   MTVNYDFSGKVVLVTGAGSGIGRATALAFAQSGAS-VAVADISTDHGLKT-VELVKAEGG 58

Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVN 341
           +  F+  DV  E     +L  VV   GG+D+  NNA +  + + +       +++ I+VN
Sbjct: 59  EATFFHVDVGSEPSVQSMLAGVVAHYGGLDIAHNNAGIEANIVPLAELDSDNWRRVIDVN 118

Query: 342 VTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 521
           ++++       I +M K     GG ++N +S + L   + +  Y ATK  V+  +     
Sbjct: 119 LSSVFYCLKGEIPLMLKRG---GGAIVNTASASGLIGGYRLSGYTATKHGVVGLTKAAA- 174

Query: 522 PEHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQL 653
              ++   +R+  VC G  D+  L D      D+ L  + + +L
Sbjct: 175 -IDYANQNIRINAVCPGPVDSPFLADMPQPMRDRLLFGTPIGRL 217


>UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyces
           avermitilis|Rep: Putative dehydrogenase - Streptomyces
           avermitilis
          Length = 258

 Score = 81.8 bits (193), Expect = 1e-14
 Identities = 59/199 (29%), Positives = 104/199 (52%), Gaps = 6/199 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           +VV I+GAA G GE   R+ ++EG K + + D+ ++ G++L  E+ ++Y         DV
Sbjct: 7   RVVLISGAARGQGEQEARLFVEEGAK-VVVADVLDDQGEALAKEIGARY------VHLDV 59

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGI----YKKAIEVNVTALITSTLK 371
             E+ +   +       G ID ++NNA ++  ND +G     +++ ++VN   +    +K
Sbjct: 60  GREDDWQAAVTVAKDAYGHIDGLVNNAGILRFNDLVGTPLAEFQQIVQVNQVGVFLG-IK 118

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
            +    + +G  GGT++N +S A LT    +  Y ATK A++  +  +   E  +K  +R
Sbjct: 119 TVAPEIEAAG--GGTIVNTASYAGLTGMAYVGAYTATKHAIVGLTR-VAALELAAKK-IR 174

Query: 552 VLTVCFGATDTALLTDEKL 608
           V  VC GA DTA+    +L
Sbjct: 175 VNAVCPGAIDTAMSNPSQL 193


>UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3;
           Bacillus|Rep: Cyclohexanol dehydrogenase - Bacillus sp.
           SG-1
          Length = 279

 Score = 81.8 bits (193), Expect = 1e-14
 Identities = 54/197 (27%), Positives = 98/197 (49%), Gaps = 7/197 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           ++K   ITGA +G+G+S    L  EG+  IA++DI EE G    VE+  + G    F ++
Sbjct: 31  ENKAAIITGAGSGLGQSAAVRLAKEGI-DIAVVDINEEGGNE-TVEMVKQKGVNAIFIKA 88

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNVTALITS 362
           DV+  E     ++  V+E G +D   NNA +       +N  I   ++ + +N+   +  
Sbjct: 89  DVSKAEEVKNYVDKTVEEFGKVDYFFNNAGISGSGQYFLNTEIEEIEQVVSINLMGALYG 148

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
                E+M K+    GG+++N +S A +     +  Y ATK  ++  +  +     ++K 
Sbjct: 149 VRYVAEVMMKNG---GGSIVNTASSAGVIGQDSVVTYSATKHGIIGLTKSM--VAEYAKE 203

Query: 543 GVRVLTVCFGATDTALL 593
           G+RV  +  G T+T ++
Sbjct: 204 GLRVNAIAPGPTETPMV 220


>UniRef50_Q6UWP2 Cluster: Dehydrogenase/reductase SDR family member
           11 precursor; n=30; Euteleostomi|Rep:
           Dehydrogenase/reductase SDR family member 11 precursor -
           Homo sapiens (Human)
          Length = 260

 Score = 81.8 bits (193), Expect = 1e-14
 Identities = 59/199 (29%), Positives = 99/199 (49%), Gaps = 11/199 (5%)
 Frame = +3

Query: 21  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--KSLQVELNSK-YGNKTK 191
           W+D++  +TGA+ GIG +V R L+ +G+K   ++  A   G  + L  E  S  Y     
Sbjct: 9   WRDRLALVTGASGGIGAAVARALVQQGLK---VVGCARTVGNIEELAAECKSAGYPGTLI 65

Query: 192 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTAL 353
            YR D+++EE  L + +A+  +  G+D+ INNA       L++ S   +K    VNV AL
Sbjct: 66  PYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLAL 125

Query: 354 ITSTLKAIEIMGKHSGGKGGTVINVSSVAA--LTQSHVMPIYFATKSAVLQFSNCIGRPE 527
              T +A + M K      G +IN++S++   +    V   Y ATK AV   +  + +  
Sbjct: 126 SICTREAYQSM-KERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQEL 184

Query: 528 HFSKTGVRVLTVCFGATDT 584
             ++T +R   +  G  +T
Sbjct: 185 REAQTHIRATCISPGVVET 203


>UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia sp. (strain
           383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
           / R18194))
          Length = 258

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 55/190 (28%), Positives = 97/190 (51%), Gaps = 3/190 (1%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  +TG A G+G +  R+ + EG   + I D+ +  G++L  EL    G+  +F R DV
Sbjct: 7   KVAIVTGGARGMGAATCRLFVAEGAC-VVIGDVLDAEGEALAREL----GDAARFMRLDV 61

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGIYKKAIEVNVTALITSTLKAIEI 383
            DE +++ + +A +++ G IDV++NNAA++       + K+  E  V+  +  T   I  
Sbjct: 62  ADEANWVRVTDATMEQFGRIDVLVNNAAVLTFGGITELSKRDFERAVSINLVGTFVGIRT 121

Query: 384 MGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
           +  H    K G+++N+SSV  L   + +  Y ++K  V   +            GVRV +
Sbjct: 122 IAPHMIAQKSGSIVNISSVDGLRGVNALAAYVSSKWGVRGLTKVAAL--ELGHQGVRVNS 179

Query: 561 VCFGATDTAL 590
           +  G  +TA+
Sbjct: 180 IHPGGVNTAM 189


>UniRef50_Q28GY1 Cluster: Novel protein containing short chain
           dehydrogenase domain; n=4; Deuterostomia|Rep: Novel
           protein containing short chain dehydrogenase domain -
           Xenopus tropicalis (Western clawed frog) (Silurana
           tropicalis)
          Length = 255

 Score = 81.0 bits (191), Expect = 2e-14
 Identities = 60/197 (30%), Positives = 96/197 (48%), Gaps = 9/197 (4%)
 Frame = +3

Query: 21  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-Y 197
           WK +V  +TGA+ GIG +V R+L+  G+K +      ++  K L  E  S     T F Y
Sbjct: 4   WKGRVALVTGASVGIGAAVARVLVQHGMKVVGCARSVDKIEK-LAAECQSAGYPGTLFPY 62

Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALIT 359
           + D+++EE  L + +A+     G+DV INNA       L++     ++  I+VNV AL  
Sbjct: 63  KCDLSNEEEILSMFSAIKTLHQGVDVCINNAGLARPEPLLSGKTEGWRTMIDVNVLALSI 122

Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYF--ATKSAVLQFSNCIGRPEHF 533
            T +A + M K      G +IN++SV           +F  ATK  V   +  I +    
Sbjct: 123 CTREAYQSM-KERNIDDGHIININSVLGHIYQCAKQAHFYCATKHTVTALTEAIRQELRE 181

Query: 534 SKTGVRVLTVCFGATDT 584
            K+ +RV ++  G  +T
Sbjct: 182 LKSHIRVTSISPGLVET 198


>UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=1; Hyphomonas
           neptunium ATCC 15444|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family - Hyphomonas neptunium
           (strain ATCC 15444)
          Length = 262

 Score = 81.0 bits (191), Expect = 2e-14
 Identities = 53/192 (27%), Positives = 93/192 (48%), Gaps = 2/192 (1%)
 Frame = +3

Query: 21  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
           +++KV  ITGAA+GIG +  R+L  EG  H+ + D+ +  GKS+  +L    G      +
Sbjct: 6   FENKVAVITGAASGIGAATARLLAREGA-HVVLADVNDNGGKSIAADL----GPTAMAVK 60

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSIGIYKKAIEVNVTALITSTLKA 374
            DV+       ++ A V+  G ID++ NNA +     S+ I     E  +   + S   A
Sbjct: 61  CDVSSAAEVEALVKAAVERHGRIDILFNNAGIGSFGTSVEIQPAEWERVIAIDLHSVYYA 120

Query: 375 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
                 H   +G  ++N +S++ L   +    Y A K AV+ ++  +   +H  + G+RV
Sbjct: 121 CHFAIPHM-PRGSAIVNTASISGLGGDYRFAAYNAAKGAVVNYTRALA-VDH-GRDGIRV 177

Query: 555 LTVCFGATDTAL 590
             +C G  +T +
Sbjct: 178 NALCPGLVETPI 189


>UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Alphaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Parvibaculum
           lavamentivorans DS-1
          Length = 268

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 56/197 (28%), Positives = 95/197 (48%), Gaps = 9/197 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  +TGAA GIG +  + L  EG K +   D   E G+ +  E+  + G  T F+R DV
Sbjct: 7   KVAIVTGAAKGIGAATAKALAREGAK-VVCSDFDAENGQVVADEIAGEGGTAT-FFRHDV 64

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITSTL 368
           TDE  +  ++    ++ GG+ VV+NNA +  +       ++  ++  IEV++ ++     
Sbjct: 65  TDEAQWEAVVKLAEEKFGGLHVVVNNAGIAPEAGPIEEKTLADWRHTIEVDLDSVFLGCK 124

Query: 369 KAIEIMGKHS--GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
             I  + K++  GG GG ++N+SS+  L        Y A K  V   +         +  
Sbjct: 125 HGIRTIKKYTSKGGAGGAIVNISSILGLVGQSGASDYNAAKGGVRLLTKSAALECADAGY 184

Query: 543 GVRVLTVCFGATDTALL 593
            +RV +V  G  DT ++
Sbjct: 185 NIRVNSVHPGYIDTPMV 201


>UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;
           n=2; Thermotoga|Rep: Uncharacterized oxidoreductase
           TM_0325 - Thermotoga maritima
          Length = 251

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 62/194 (31%), Positives = 95/194 (48%), Gaps = 6/194 (3%)
 Frame = +3

Query: 21  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
           ++ KVV ITGA +GIG+    +  + G K +AI DI+EE GK   VEL    G +  F  
Sbjct: 3   FQGKVVLITGAGSGIGKKAAVMFAERGAK-VAINDISEEKGKE-TVELIKSMGGEAAFIF 60

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITS 362
            DV  +     I+   V+  G +D+++NNA ++        S   + K + VNV      
Sbjct: 61  GDVAKDAE--QIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFLL 118

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
           +  A+E M K     GG ++NVSS A L       +Y  +K+A+L  +  +     +   
Sbjct: 119 SKYAVEQMKKQG---GGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLA--VDYVDY 173

Query: 543 GVRVLTVCFGATDT 584
           G+RV  VC G T +
Sbjct: 174 GIRVNAVCPGTTQS 187


>UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=1; Bacillus halodurans|Rep:
           3-oxoacyl-(Acyl-carrier protein) reductase - Bacillus
           halodurans
          Length = 247

 Score = 80.2 bits (189), Expect = 4e-14
 Identities = 55/222 (24%), Positives = 105/222 (47%), Gaps = 10/222 (4%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           +DKV  +TGA  GIG+ +V+  +++G     I     EA + ++  LN   G K   Y S
Sbjct: 4   RDKVAIVTGATRGIGKEIVKTFVEQGAFVYGIYASNHEAAREIEKTLNQ--GEKCVSYVS 61

Query: 204 DVTDEEHFL-GILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 362
              D++ F+  +  +VV +   +D+++NNA +  D          +++ ++VN     T 
Sbjct: 62  GSVDDQLFIHSLFKSVVDKHNRLDILVNNAGITRDQFLFQMDDQSWQQVLQVNFGGTYTC 121

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
              A+  M +   GK   ++NV SV  +        Y A+K A++  +  + R   +S+ 
Sbjct: 122 CHAALPYMERKKQGK---IVNVVSVTGVVGREAQTNYGASKGAIIGLTRLLAR--KYSEK 176

Query: 543 GVRVLTVCFGATDTALL---TDEKLGTFDKYLESSCLDQLKK 659
           G+ +  +  G  +T ++    +EKL  F ++  +  L   K+
Sbjct: 177 GISINAIAPGMIETEMIKQVPEEKLKNFLRFTNAKKLGSTKE 218


>UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Chloroflexus|Rep: Short-chain
           dehydrogenase/reductase SDR - Chloroflexus aggregans DSM
           9485
          Length = 256

 Score = 80.2 bits (189), Expect = 4e-14
 Identities = 60/198 (30%), Positives = 98/198 (49%), Gaps = 6/198 (3%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
           E++ KV  +TG A GIG +    L  EG   + I D  + A  +  VE  + +G +    
Sbjct: 2   EFQGKVAIVTGGAQGIGRATALALAREGAA-VVIAD-RDAAATTALVEGINAWGGRALAV 59

Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALIT 359
            +DV+DE     I N  V E GGID+++NNA +       + ++ ++++ I VN+T +  
Sbjct: 60  IADVSDESDAARIANDTVLEFGGIDLLVNNAGIQQPGTIESTTLQLWQEIINVNLTGVF- 118

Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
             L +  +M +     GG ++NV+SV  L        Y A+K  V+  +  +      + 
Sbjct: 119 --LVSRFVMPELRRRGGGAIVNVASVYGLRAEAGWAAYAASKGGVIALTRAMALDG--AP 174

Query: 540 TGVRVLTVCFGATDTALL 593
            G+RV  VC G  DT+LL
Sbjct: 175 DGIRVNCVCPGLIDTSLL 192


>UniRef50_Q8YQR6 Cluster: All3753 protein; n=6; Bacteria|Rep:
           All3753 protein - Anabaena sp. (strain PCC 7120)
          Length = 263

 Score = 79.8 bits (188), Expect = 6e-14
 Identities = 60/192 (31%), Positives = 94/192 (48%), Gaps = 6/192 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           +   ITGAA+GIG  +V I  +    ++ ++D A+E  + + +E   K+G   K    D+
Sbjct: 7   QTALITGAASGIGYELVCIFAENDY-NLVLVDRAKEKLEEIAIEFQDKFGISVKPIVRDL 65

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA-----LMNDS-IGIYKKAIEVNVTALITSTLK 371
           +       I   V Q    +DV++NNA      L ND+ +    + ++VNV      T  
Sbjct: 66  SKTTSPEEIFQEVEQANIKVDVLVNNAGFGTYGLFNDTNLTDELEMLQVNVVCTTHLTKL 125

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
            ++ M +   GK   ++NVSS AA     +M +YFATK+ VL FS  +        TGV 
Sbjct: 126 FLKNMVQQGEGK---ILNVSSAAAFQPGPLMAVYFATKAYVLSFSEALA--NELDGTGVT 180

Query: 552 VLTVCFGATDTA 587
           V  +C G T +A
Sbjct: 181 VTVLCPGTTQSA 192


>UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2;
           Actinomycetales|Rep: Short chain dehydrogenase -
           Rhodococcus sp. (strain RHA1)
          Length = 267

 Score = 79.8 bits (188), Expect = 6e-14
 Identities = 58/190 (30%), Positives = 93/190 (48%), Gaps = 7/190 (3%)
 Frame = +3

Query: 42  ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTDEE 221
           +TG A G+G  +   L D G   + I D+ EE G++    +  K G  T F + DVTD+ 
Sbjct: 13  VTGGAKGLGAGMAAALADAGAA-VVIGDVLEEEGRATADSVG-KTGVDTGFVKLDVTDDG 70

Query: 222 HFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLKAIEI 383
           ++   + A V++ GG+D+++NNA +   S+ +       ++  EVN+  +       +  
Sbjct: 71  NWERAVAATVEQLGGLDLLVNNAGIEISSLVVDIDPADIRRMCEVNILGVALGLKHGLRA 130

Query: 384 MGK-HSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
           M    + G GG ++NVSSVAA      +  Y ATKSAV + +    +       GVRV  
Sbjct: 131 MRPGGAAGSGGAIVNVSSVAATIPFPGIAGYSATKSAVDRLTRVAAQEAGKLGYGVRVNC 190

Query: 561 VCFGATDTAL 590
           V  G   T +
Sbjct: 191 VYPGLVATEM 200


>UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Leeuwenhoekiella blandensis MED217
          Length = 257

 Score = 79.8 bits (188), Expect = 6e-14
 Identities = 49/167 (29%), Positives = 88/167 (52%), Gaps = 6/167 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           K+KV  +TG A+G+G+S  ++L  EG K I + DI EE GK + V+   + G +  F + 
Sbjct: 5   KNKVAIVTGGASGLGKSSAKLLAREGAK-IVVSDIDEEGGKKV-VQQIKEDGGEAIFIKQ 62

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL-----MND-SIGIYKKAIEVNVTALITST 365
           DV  E+ +  ++   ++  G + ++ N+A +     + D ++  +K  I++N+      T
Sbjct: 63  DVAKEDEWKNVIETTLETYGKLHILANSAGIGLGGTVEDVTLEDWKNLIDINLNGTFLGT 122

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 506
              I+  G     +GG++IN SS+  L     +P Y A+K  V  F+
Sbjct: 123 KYGIK--GMRKTDEGGSIINFSSIEGLIGDPNLPAYNASKGGVTIFT 167


>UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;
           n=15; Staphylococcus|Rep: Uncharacterized oxidoreductase
           SSP0419 - Staphylococcus saprophyticus subsp.
           saprophyticus (strain ATCC 15305 /DSM 20229)
          Length = 234

 Score = 79.8 bits (188), Expect = 6e-14
 Identities = 59/209 (28%), Positives = 105/209 (50%), Gaps = 7/209 (3%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAI-LDIAEEAGKSLQVELNSKYGNKTKF 194
           E +DKV  +TGA++GIG S+   L ++GVK +    D +  A  + +++ N +   +T  
Sbjct: 3   ELQDKVAVVTGASSGIGASIAETLANQGVKVVLTGRDESRLAEVAKRIQDNKQAVVETSI 62

Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALI 356
              DVT +E    ++    ++ G ID+++N+A LM  S      +  ++  I+VN+   +
Sbjct: 63  V--DVTHKEEVTELVEKTKEKFGQIDILVNSAGLMLSSAITEGDVEAWEAMIDVNIKGTL 120

Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
            +    +  M   S G    +IN++S++    +    +Y A+K+AV   +   G  +  +
Sbjct: 121 YTINAVLPSMLNQSSGH---IINIASISGFEVTKKSTLYSASKAAVHSITQ--GLEKELA 175

Query: 537 KTGVRVLTVCFGATDTALLTDEKLGTFDK 623
           KTGVRV ++  G  DT L  D   G   K
Sbjct: 176 KTGVRVTSISPGMVDTPLSGDTDWGARKK 204


>UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4;
           Brucellaceae|Rep: GLUCOSE 1-DEHYDROGENASE II - Brucella
           melitensis
          Length = 272

 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 58/197 (29%), Positives = 95/197 (48%), Gaps = 6/197 (3%)
 Frame = +3

Query: 21  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
           +KDKVV +TG A+GIGE+  R  + EG K + I D ++  G+ L  EL   +  +  F +
Sbjct: 3   FKDKVVIVTGGASGIGEATARAFIREGAK-VVIADFSDH-GQQLADELAGAH-EQALFIK 59

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITS 362
           +DV D      ++   V+  G +D++  NA +  D+         ++K I++N+T +   
Sbjct: 60  TDVADTRAVQALIARTVENYGRLDIMFANAGIAADAPIDELDEAAWQKTIDINLTGVYLC 119

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
              AI+ M   S G GG ++N  S+ +      +  Y A K  V   +  +     +   
Sbjct: 120 DKYAIDQM--RSQG-GGVIVNCGSIHSHVGKSGVTAYAAAKGGVKLLTQTLA--IDYGPQ 174

Query: 543 GVRVLTVCFGATDTALL 593
            +RV  VC G  DT LL
Sbjct: 175 NIRVNAVCPGYIDTPLL 191


>UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep:
           CylG - Streptococcus agalactiae
          Length = 240

 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 53/197 (26%), Positives = 96/197 (48%), Gaps = 7/197 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  +TG   GIG ++ + L  EG K IAI +  +   ++LQ EL      K   Y+ ++
Sbjct: 2   KVAIVTGGTRGIGRAITKELYKEGYKVIAIYNSNDAKARALQEEL-----PKLDVYKCNI 56

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 371
           +D +    ++  + +E GGID ++NNA ++ D   +      +   I +N+  L+  +  
Sbjct: 57  SDAKAVQKLVTKIFREYGGIDCLVNNAGIVRDGFFLMMSKEKWMDVININIMGLVNMSKA 116

Query: 372 AIEIM-GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
            ++IM  K   GK   VIN+SS + +        Y ATK A++  +  + +   F+  G+
Sbjct: 117 VLKIMKAKRIQGK---VINISSTSGIAGQIGQANYSATKGAIISITKTLAK--EFASDGI 171

Query: 549 RVLTVCFGATDTALLTD 599
            +  V  G  +T +  +
Sbjct: 172 TINCVSPGFIETDMTNE 188


>UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9;
           Bacteria|Rep: Cyclopentanol dehydrogenase - Comamonas
           sp. (strain NCIMB 9872)
          Length = 250

 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 52/166 (31%), Positives = 84/166 (50%), Gaps = 6/166 (3%)
 Frame = +3

Query: 27  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
           DKVV +TG A G+G +   +L  EG   + + D+ EE G     E+  + G K  F   D
Sbjct: 6   DKVVLVTGGAMGMGLTHCTLLAREGAT-VYLSDMNEELGHQAVAEIR-RQGGKAHFLHLD 63

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 368
           VT+E H+ G ++ ++ E   +D ++NNA ++      + S   + +  E+NV ++   T 
Sbjct: 64  VTNENHWTGAVDTILAESDRLDALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTR 123

Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 506
             IE M K      G ++NVSS+  L  +     Y A+K AV  F+
Sbjct: 124 AVIEPMRK---AHKGCIVNVSSIYGLVGAPGAAAYEASKGAVRLFT 166


>UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein)
           reductase; n=9; Firmicutes|Rep: 3-oxoacyl-(Acyl carrier
           protein) reductase - Oceanobacillus iheyensis
          Length = 253

 Score = 79.0 bits (186), Expect = 1e-13
 Identities = 51/201 (25%), Positives = 102/201 (50%), Gaps = 7/201 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           KDKV  +TGAA+G+G+++  +   EG K + + D+ EE  +S+  E+ S  G  T   + 
Sbjct: 4   KDKVAIVTGAASGMGKAIATLYASEGAK-VIVADLNEEGAQSVVEEITSNNGVATAI-KV 61

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN--DSIG-----IYKKAIEVNVTALITS 362
           ++  +E    +++  V   G +D+++NNA +M+  +++G      +    ++N   ++ +
Sbjct: 62  NIAQKEDIDKMIDTAVDTYGTLDILVNNAGIMDGFEAVGDVEDDRWDLIFDINTKGVMRA 121

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
             KAI I  +    + G ++N +S   L  +H    Y A+K AV+  +   G    ++ +
Sbjct: 122 MRKAIPIFLEK---ESGVIVNTASTGGLNGAHAGAAYGASKHAVIGLTKNTG--YMYANS 176

Query: 543 GVRVLTVCFGATDTALLTDEK 605
           G+R   +  G   T + +  K
Sbjct: 177 GIRCNAIAPGGVATNITSSLK 197


>UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductase;
           n=3; Lactobacillales|Rep: 3-oxoacyl-acyl carrier protein
           reductase - Lactobacillus brevis (strain ATCC 367 / JCM
           1170)
          Length = 249

 Score = 79.0 bits (186), Expect = 1e-13
 Identities = 58/205 (28%), Positives = 102/205 (49%), Gaps = 8/205 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           M+   KDKV  ITG   GIG  +    + EG K +   +   + G++      +K+G+  
Sbjct: 1   MTDRLKDKVAIITGGVAGIGLGIAECYVREGAKVVVTANHNVDGGRAAV----AKFGDDV 56

Query: 189 K-FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSI-----GIYKKAIEVNV 344
             F + DV+ E  +  +++A + + G +D+++NNA +  +N +I       ++K I+VN+
Sbjct: 57  SLFVQQDVSKEADWQKVIDATIAKFGRVDILVNNAGIGGVNTAIEDLDLADWQKVIDVNL 116

Query: 345 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 524
           TA       AI+ M K +    G++INVSSVA L    + P Y A+K      ++     
Sbjct: 117 TANFLGEKAAIKAM-KQTADAKGSIINVSSVAGLVGLPMAPAYSASKGGSRLLTHATALN 175

Query: 525 EHFSKTGVRVLTVCFGATDTALLTD 599
                  +RV +V  G  DT+++ +
Sbjct: 176 LAQRGIDIRVNSVHPGWIDTSIVPE 200


>UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Solibacter usitatus Ellin6076|Rep: Short-chain
           dehydrogenase/reductase SDR - Solibacter usitatus
           (strain Ellin6076)
          Length = 275

 Score = 79.0 bits (186), Expect = 1e-13
 Identities = 59/196 (30%), Positives = 97/196 (49%), Gaps = 6/196 (3%)
 Frame = +3

Query: 21  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
           ++ KV F+TG  +G+G ++   L   G   IA+ DI  EA + +   +    G K+   +
Sbjct: 4   FQGKVAFVTGGGSGLGRALSEELARRGAV-IAVTDINAEAAEHVAAAITES-GGKSCSMK 61

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN----DSIGI--YKKAIEVNVTALITS 362
            DV+  E     +++VV   G +D + NNA ++       +G+  + + I+VN+  ++  
Sbjct: 62  LDVSQPEDVAASIDSVVGRYGRLDYMFNNAGIIILGEVRDMGLEHWHRLIDVNLLGVLYG 121

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
           T  A   M +   G    ++N++SV  L        Y ATK AV+  S  + RPE  SK 
Sbjct: 122 TTAAYSHMVRQGYGH---IVNIASVGGLVPLPTYAAYAATKHAVVGLSTSM-RPE-ASKL 176

Query: 543 GVRVLTVCFGATDTAL 590
           GVR+  VC G  +T L
Sbjct: 177 GVRITVVCPGTMNTGL 192


>UniRef50_A1IFS9 Cluster: Short chain dehydrogenase family protein;
           n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Short
           chain dehydrogenase family protein - Candidatus
           Desulfococcus oleovorans Hxd3
          Length = 273

 Score = 79.0 bits (186), Expect = 1e-13
 Identities = 60/194 (30%), Positives = 96/194 (49%), Gaps = 6/194 (3%)
 Frame = +3

Query: 27  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
           DKV  +TG A+G+G +V  +L   G   + I DI  E+ + +   + +  G  T  +  D
Sbjct: 6   DKVFIVTGGASGMGRAVCELLGTRGA-ILIIADIDGESAEKVAAGITAAGGRATGVF-LD 63

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 368
            T +E    +++    E G +D + NNA ++      + S   + + ++VN   ++T TL
Sbjct: 64  TTADETVRRLVDETAAEYGRLDYMFNNAGILIAGEVRDMSDDHWARILDVNFRGVLTGTL 123

Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
            A  IM +   G    +IN +S A L    V+  Y  TK AV+  S  + RPE  +K GV
Sbjct: 124 AAYRIMVEQGFGH---IINTASTAGLVPIPVITAYATTKHAVVGLSISL-RPE-AAKAGV 178

Query: 549 RVLTVCFGATDTAL 590
           RV  VC G   T++
Sbjct: 179 RVSVVCPGYVSTSI 192


>UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=4; Sphingomonas|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Pseudomonas paucimobilis (Sphingomonas paucimobilis)
          Length = 250

 Score = 79.0 bits (186), Expect = 1e-13
 Identities = 63/200 (31%), Positives = 97/200 (48%), Gaps = 6/200 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           M++    KV  ITG A+G+G +  +   +EG K + I D+ EE  K +  E+ +  G   
Sbjct: 1   MANRLAGKVALITGGASGLGAAQAKRFAEEGAK-VVIGDLNEEMAKGVVAEIRAA-GGDA 58

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTA 350
            F R DVTD   +   + A V   GG+  + N A +++      +SI  + K + VN TA
Sbjct: 59  LFIRLDVTDAASWNNAIAAAVDGFGGLTTLSNTAGIIHPGGFEEESIEGWNKMVAVNQTA 118

Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
           +      AI  + K SG   G++IN+SS+  +  +     Y ATK+AV   S        
Sbjct: 119 IFLGIKAAIPELVK-SG--NGSIINISSLIGMFPTAGNASYCATKAAVRIMSKAAAL--E 173

Query: 531 FSKTGVRVLTVCFGATDTAL 590
           F   GVRV T+  G  +T +
Sbjct: 174 FVDRGVRVNTIVPGGMNTPI 193


>UniRef50_P19871 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=4;
           Burkholderiales|Rep: 3-beta-hydroxysteroid dehydrogenase
           - Comamonas testosteroni (Pseudomonas testosteroni)
          Length = 254

 Score = 79.0 bits (186), Expect = 1e-13
 Identities = 51/168 (30%), Positives = 92/168 (54%), Gaps = 6/168 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           M++  + KV  +TG A+G+G  VV++LL EG K +A  DI E AG+ L  EL    G ++
Sbjct: 1   MTNRLQGKVALVTGGASGVGLEVVKLLLGEGAK-VAFSDINEAAGQQLAAEL----GERS 55

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 350
            F R DV+ E  +  ++ AV +  G ++V++NNA ++         +  + + +++N  +
Sbjct: 56  MFVRHDVSSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTES 115

Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 494
           +     + I  M +     GG++IN++SV++         Y A+K+AV
Sbjct: 116 VFIGCQQGIAAMKE----TGGSIINMASVSSWLPIEQYAGYSASKAAV 159


>UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular
           organisms|Rep: Glucose 1-dehydrogenase - Oceanobacillus
           iheyensis
          Length = 256

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 59/197 (29%), Positives = 94/197 (47%), Gaps = 7/197 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           +DKV  +TGAA G+G++   IL  E    + I D  EE G+ + VE   + G +  F + 
Sbjct: 7   EDKVAIVTGAAMGMGKATA-ILFAESKAKVVIADFNEEKGQEV-VEEVKQAGGQAAFIKV 64

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITS 362
           D++D      ++   V + G +D+ +NNAAL  D           + K I V++T   T+
Sbjct: 65  DISDSAQVKQMVQFAVDQFGKLDIAVNNAALTPDDKPASEFDEDYWDKLISVDLTG--TA 122

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
                E+      G GG+++N+SSV+          Y A K  V+  +  +   E+    
Sbjct: 123 LCMKYELQQLLEQGNGGSIVNISSVSGFRPQPNNIAYVAAKHGVVGMTK-VAALEN-GPQ 180

Query: 543 GVRVLTVCFGATDTALL 593
            +RV TV  GA DT +L
Sbjct: 181 NIRVNTVAPGAIDTPML 197


>UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SDR)
           family protein; n=1; Thermobifida fusca YX|Rep:
           Short-chain dehydrogenase/reductase (SDR) family protein
           - Thermobifida fusca (strain YX)
          Length = 282

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 57/194 (29%), Positives = 94/194 (48%), Gaps = 5/194 (2%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           M+   + +V  ITG A+GIGE+ VR    EG   + I DI  EAG+ L  EL    G++ 
Sbjct: 1   MTQRLRGRVAAITGGASGIGEATVRRFHTEGAS-VVIADIQAEAGRRLADEL----GDRA 55

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 368
            F R+DV++E     +++  V   G +D+++NNA +M  ++G        +    I   L
Sbjct: 56  VFVRTDVSEEADVAALVDTAVDRFGQLDIMVNNAGIMG-ALGPIDATRMSDADLTIAVNL 114

Query: 369 KAIEIMGKHSG-----GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533
           + +    KH+       + G +I+ SS A +       IY A K  ++  SN +      
Sbjct: 115 RGVICGMKHAARVMKPRRSGVIISTSSPAGVLGGIGPHIYSAVKVGIIGLSNSVA--AEL 172

Query: 534 SKTGVRVLTVCFGA 575
            + G+RV T+  G+
Sbjct: 173 RQHGIRVNTIIPGS 186


>UniRef50_Q399N8 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=27; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Burkholderia sp. (strain 383) (Burkholderia
           cepacia (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 595

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 7/201 (3%)
 Frame = +3

Query: 12  SHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAI-LDIAEEAGKSLQVELNSKYGNKT 188
           S  +  KV  +TGA +GIG         EG   +A  +D+A     +L + L    G + 
Sbjct: 322 SGRFSGKVAVVTGAGSGIGRCAALAFAREGATIVACDIDLASAERTALLIGLT---GAQA 378

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTA 350
              R DV   +    +   V    GG DVVINNA +      ++ S   +++ + VN+  
Sbjct: 379 HAKRVDVGSADEMEALATWVGSALGGADVVINNAGIGMAGGILDTSTRHWERILHVNLWG 438

Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
           +I  +    + M     G GG ++N +S AA   S  +P Y  TK+AVL  S C+ R E 
Sbjct: 439 VIHGSRLFAQQMAAR--GTGGHIVNTASAAAFGPSRDLPAYATTKAAVLMLSECM-RAE- 494

Query: 531 FSKTGVRVLTVCFGATDTALL 593
            ++ G+ V  VC G  +T ++
Sbjct: 495 LAEQGIGVTAVCPGFAETGIM 515


>UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=3;
           Clostridium|Rep: 7-alpha-hydroxysteroid dehydrogenase -
           Eubacterium sp. (strain VPI 12708)
          Length = 266

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 53/211 (25%), Positives = 105/211 (49%), Gaps = 10/211 (4%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
           KDKV+ +T +  GIG ++ +    EG K ++   ++  E  K+   E+N+  GN  K+  
Sbjct: 4   KDKVILVTASTRGIGLAIAQACAKEGAKVYMGARNL--ERAKARADEMNAAGGN-VKYVY 60

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINN---------AALMNDSIGIYKKAIEVNVTAL 353
           +D T EE ++ ++  +++++G IDV++NN           + N    ++ K + +N+ ++
Sbjct: 61  NDATKEETYVTMIEEIIEQEGRIDVLVNNFGSSNPKKDLGIANTDPEVFIKTVNINLKSV 120

Query: 354 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533
             ++  A++ M ++    GG++IN+SSV  L        Y  +K+A+   +  I    H 
Sbjct: 121 FIASQTAVKYMAENG---GGSIINISSVGGLIPDISQIAYGTSKAAINYLTKLIA--VHE 175

Query: 534 SKTGVRVLTVCFGATDTALLTDEKLGTFDKY 626
           ++  +R   V  G T T  + D     F  +
Sbjct: 176 ARHNIRCNAVLPGMTATDAVQDNLTDDFRNF 206


>UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=2; Bacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Methylobacterium
           sp. 4-46
          Length = 255

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 59/203 (29%), Positives = 96/203 (47%), Gaps = 6/203 (2%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  +TG A GIG +  R   +EG   + + DI  EAG +     N  +    +F   DV
Sbjct: 7   KVALVTGGARGIGLATARRFAEEGAAAVILADIDAEAG-ARAAATNPVF----RFAPLDV 61

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL----MNDSIGI--YKKAIEVNVTALITSTLK 371
           T +  +    +  V  +GG+DVV+N A +      +S+ +  +++   VNV         
Sbjct: 62  TQDAAWQDATDEAVAREGGLDVVVNCAGIAVVATIESVTLEQWRRVQAVNVDGTFLGCRH 121

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           A+ +M K   G+GG +IN+SSV+ +   H +  Y A+K AV   +  +         G+R
Sbjct: 122 AVRVM-KPPAGRGGAIINLSSVSGIIGGHNLAAYNASKGAVRLLTKSVALHCARQGYGIR 180

Query: 552 VLTVCFGATDTALLTDEKLGTFD 620
             ++  G T+T +L D   G  D
Sbjct: 181 CNSIHPGFTETDMLHDLAAGGRD 203


>UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2;
           Gammaproteobacteria|Rep: Short chain dehydrogenase -
           marine gamma proteobacterium HTCC2143
          Length = 259

 Score = 78.6 bits (185), Expect = 1e-13
 Identities = 54/210 (25%), Positives = 95/210 (45%), Gaps = 5/210 (2%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           MS  +  +V  +TG A GIG +       EG+ ++ + D+ ++ G+     + +  GN  
Sbjct: 1   MSTTFSGQVALVTGGAAGIGRTTAAAFAREGL-NVVVADMDKDGGEETVAAIKAAGGNAI 59

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 368
            F   DVT E     ++       G +D   NNA +  +  G   K  E    +++   +
Sbjct: 60  -FVPCDVTKESDVQWLIETTCSTYGSVDYAFNNAGIDIEK-GELSKGTEDEFDSIMAVNV 117

Query: 369 KAIEIMGKHSGGK-----GGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533
           K + +  KH   +     GGT++N SS+  L  +  M IY A+K AV+  +         
Sbjct: 118 KGVWLCMKHQITQMITQGGGTIVNTSSIGGLGAAPNMSIYCASKHAVIGLTKSAAVEN-- 175

Query: 534 SKTGVRVLTVCFGATDTALLTDEKLGTFDK 623
           ++ G+R+  VC G  DT +    ++  FD+
Sbjct: 176 ARNGIRINAVCPGVIDTNMFNRSRM--FDR 203


>UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20;
           Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
           Oceanobacillus iheyensis
          Length = 255

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 67/202 (33%), Positives = 100/202 (49%), Gaps = 13/202 (6%)
 Frame = +3

Query: 42  ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTDEE 221
           +TG A+G+GE+ VR L ++G K +AI D+ +E G+ L  EL    G+   +++ DVTDE 
Sbjct: 10  VTGGASGLGEATVRRLHNQGGK-VAIFDLNKENGERLATEL----GDNVDYFQVDVTDET 64

Query: 222 HFLGILNAVVQEQGGIDVVINNA--ALMNDSIG--------IYKKAIEVNVTALITSTLK 371
                L+ V+++  GI  V+N A  A+   +IG         +   IE+N+         
Sbjct: 65  SVQKALDNVMEQSDGIHAVVNCAGIAIAEKTIGKKGVHSLQHFSNVIEINLIGTFNVIRL 124

Query: 372 AIEIMGKHS---GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
           A E M  +S    G+ G +IN +SVAA         Y A+K  V   +  I R    S  
Sbjct: 125 AAEKMALNSPNDEGERGVIINTASVAAFEGQIGQAAYSASKGGVAGMTLPIAR--DLSTL 182

Query: 543 GVRVLTVCFGATDTALLTDEKL 608
           G+RV+T+  G   T L   EKL
Sbjct: 183 GIRVMTIAPGLFLTPLF--EKL 202


>UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain
           dehydrogenase/reductase SDR - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 252

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 60/191 (31%), Positives = 90/191 (47%), Gaps = 6/191 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  ITG ATGIG +   +   EG   + I DI EE G S  VE     G    F R DV
Sbjct: 7   KVALITGGATGIGRATALLFAREGA-CVLIGDINEE-GASETVEAVRAAGGDAAFRRCDV 64

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 371
           + EE    ++ A  +E G +DVV  NA L+        S   ++  + +N+TA    T  
Sbjct: 65  SGEEEIAALVAAAGEEYGRLDVVFGNAGLLRTRPLEDLSTKEFELHLRINLTANFLLTKY 124

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           A  +M +H   +GG++I ++S   L  +     Y A+K  ++  +  +   +  +   +R
Sbjct: 125 AAPVMRRH---EGGSIIFMASAGGLRGTRGSVAYNASKGGLVNMTRSLA--DELAPHNIR 179

Query: 552 VLTVCFGATDT 584
           V  VC G  DT
Sbjct: 180 VNCVCPGWVDT 190


>UniRef50_A1UMZ0 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=5; Mycobacterium|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Mycobacterium
           sp. (strain KMS)
          Length = 261

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 59/200 (29%), Positives = 93/200 (46%), Gaps = 8/200 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           +V  +TG A+GIG +    L  EG++ + +LDI   A +++   +    G      R DV
Sbjct: 6   RVALVTGGASGIGRATAGRLAAEGMR-VCVLDIDGPATEAVAESIGG-IG-----LRCDV 58

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMND---SIGI-----YKKAIEVNVTALITST 365
           TD E      +  V E GG+DV   NA +  D    IG      Y+K++ VNV  ++   
Sbjct: 59  TDPEQVDSAFDTCVAELGGVDVAFLNAGITIDWSGDIGALDLAQYRKSVGVNVDGVVFGV 118

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
             A+  M     G    ++  +S+A L   H  P+Y   K  V+ F   I    + +  G
Sbjct: 119 RAAVRTMRTLDPGVDRAILATASLAGLMPWHPDPVYSLGKHGVVGFMRSIA--PNLAAEG 176

Query: 546 VRVLTVCFGATDTALLTDEK 605
           + V T+C G T+T +L D +
Sbjct: 177 IAVHTICPGITETGVLGDRR 196


>UniRef50_Q22CU9 Cluster: Oxidoreductase, short chain
            dehydrogenase/reductase family protein; n=1; Tetrahymena
            thermophila SB210|Rep: Oxidoreductase, short chain
            dehydrogenase/reductase family protein - Tetrahymena
            thermophila SB210
          Length = 843

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 58/192 (30%), Positives = 94/192 (48%), Gaps = 6/192 (3%)
 Frame = +3

Query: 36   VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 215
            V +TGAA G G+ +      +   +I I DI E+    +  E+  K G K  FY+ DV+D
Sbjct: 577  VLLTGAAMGAGKFLAMNFAKKNNCNIIIYDIREDLMGQVIEEIQ-KAGAKGYFYKCDVSD 635

Query: 216  EEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLKAI 377
            E+     + + +Q+   ID++INN  + N       S    +KA  VN  A ++   K +
Sbjct: 636  EQELQRTVESTLQKFQKIDILINNVGIANLKLFTDVSFDEVQKAFSVNFLAPVSIIKKIL 695

Query: 378  EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
             +M + + G    ++NVSSVA+L  S  M  Y A+K+A+  F N +       K  +   
Sbjct: 696  PVMIERNQGH---IVNVSSVASLMPSAKMTDYCASKAALSGFHNALRLELKQQKKNINTT 752

Query: 558  TVCFGATDTALL 593
             +C  A +T +L
Sbjct: 753  LICPYAVNTGVL 764


>UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=1; Ralstonia eutropha JMP134|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Ralstonia eutropha (strain JMP134) (Alcaligenes
           eutrophus)
          Length = 258

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 60/202 (29%), Positives = 100/202 (49%), Gaps = 8/202 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K+  +TG A+G+G +  R L  EG + +   DI   AG + + EL    G    F R DV
Sbjct: 6   KIALVTGGASGMGLAFTRRLAQEGAR-VYFTDINGAAGHATESELQGA-GLAVVFLRHDV 63

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGI-----YKKAIEVNVTALITSTLK 371
           T E  +L +L  +    G +DV++NNA + ++ +I       + + + VN+ ++      
Sbjct: 64  TQENDWLRVLEHIGAVDGRLDVLVNNAGIAISHNIETCTTEDFDRTLNVNLKSVFLGCKH 123

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG-- 545
            + +M +    KGG++INVSS+ A+    V   Y A+K+ V   S  +    H ++ G  
Sbjct: 124 GLALMKQ----KGGSIINVSSITAICGEPVALAYSASKAGVRFLSKSVAL--HCAEKGYA 177

Query: 546 VRVLTVCFGATDTALLTDEKLG 611
           +RV ++  G  DT LL     G
Sbjct: 178 IRVNSLHPGYIDTPLLAGSNAG 199


>UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family; n=3; Clostridium
           perfringens|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family - Clostridium perfringens
           (strain ATCC 13124 / NCTC 8237 / Type A)
          Length = 272

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 57/197 (28%), Positives = 98/197 (49%), Gaps = 7/197 (3%)
 Frame = +3

Query: 21  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
           + DKV+ ITGAA GIG++V      EG K + + D  EE  K    E+     N  +F  
Sbjct: 9   FSDKVMIITGAAGGIGKAVALRAAKEGAK-LVLADRKEEMSKETLKEIREITSN-VEFLI 66

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALIT 359
            D+ + E+   +++  +++ GG+D++INNA +          S  +++  ++ N+     
Sbjct: 67  CDLREGENCKKVIDTAIKKFGGLDILINNAGITGTPAPVHEMSEEMFRNVLDCNIMIAFH 126

Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
            +   I+ M K +  KGG ++NVSSVA LT       Y  +K  +   +  +     +++
Sbjct: 127 CSHYGIQEMIKQN--KGGAIVNVSSVAGLTGFPGHSAYVTSKHGLNGLTRNMAL--DYAR 182

Query: 540 TGVRVLTVCFGATDTAL 590
            G+RV  V  G TDT +
Sbjct: 183 YGIRVNAVNPGTTDTPM 199


>UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Pelobacter|Rep: Short-chain dehydrogenase/reductase
           SDR - Pelobacter propionicus (strain DSM 2379)
          Length = 283

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 57/206 (27%), Positives = 101/206 (49%), Gaps = 10/206 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  ITGA  GIG ++   L  +G   + + D+  +    +  E+ ++ G K    R+DV
Sbjct: 24  KVAIITGAGRGIGRAIALRLGADGAAMV-VSDVNGDNATKVAEEIKAR-GGKAMALRTDV 81

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVT-ALITSTL 368
           T E     +++  V++ G +D+++ NA + N  + I      + + + VN   A +  T+
Sbjct: 82  TSEADVKDLIDTAVRQHGRLDIMVANAGIANIKMSIEMTGAEWDQIMAVNTKGAFLCDTM 141

Query: 369 KAIEIMGK-HSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
            A +++ + HS   G GG +IN +S+AA +   ++  Y A+K AV  F+  + +     K
Sbjct: 142 AARQMIKQGHSETPGSGGKIINCASIAAHSGFSILAAYSASKFAVRGFTQALAKELGPYK 201

Query: 540 TGVRVLTVCFGATDTALLTDEKLGTF 617
             V         TD   L DEK+G +
Sbjct: 202 INVNAYCPGIVGTDMWTLIDEKMGPY 227


>UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep:
           Lin2278 protein - Listeria innocua
          Length = 253

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 50/197 (25%), Positives = 99/197 (50%), Gaps = 8/197 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  +TGAA+G+G+ +  +   EG K + + D+  EA +     +  + G       ++V
Sbjct: 7   KVAVVTGAASGMGQQIAVLFAKEGAK-VVVADLNLEAAQKTVALIEDEQGTALAVV-ANV 64

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITSTL 368
           T ++    ++N   +  G +D+++NNA +M++ +        ++ K   +N T ++ +T 
Sbjct: 65  TKQDDIESMINKATETYGTLDILVNNAGIMDNFVPAGELTDELWDKVFAINTTGVMRATR 124

Query: 369 KAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
           KA+ I  +    KG G ++N++S   L  S     Y A+K AV+ F+  +G    ++   
Sbjct: 125 KALHIFEE----KGQGVIVNIASAGGLFGSRAGAAYTASKHAVVGFTKNVG--FQYANKN 178

Query: 546 VRVLTVCFGATDTALLT 596
           +R   +  GA +T + T
Sbjct: 179 IRCNAIAPGAVNTNIGT 195


>UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus
           iheyensis|Rep: Oxidoreductase - Oceanobacillus iheyensis
          Length = 257

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 59/199 (29%), Positives = 105/199 (52%), Gaps = 7/199 (3%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
           +++DKV+ +TGAA GIG+ VVR + +   K + ++D+ E+A KS+Q EL     N +   
Sbjct: 3   KFQDKVIIVTGAAGGIGKEVVRKVANAQAK-VVLVDLNEDAIKSVQAELGLTEEN-SFVV 60

Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALI 356
           ++DV++EE+    ++  + + G ID  +NNA +   +  I       +     +NV  ++
Sbjct: 61  KADVSNEENVKNYVDQTIAKFGRIDGFVNNAGVEGPAKSIEEITEKEFDFVYGINVKGVL 120

Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
                 + +M      K G+++N +SVA L  S  M +Y ++K AV+   N +   E  +
Sbjct: 121 FGLKYVLPVM---KAQKSGSIVNTASVAGLIGSPSMALYNSSKHAVMGL-NKVAALES-A 175

Query: 537 KTGVRVLTVCFGATDTALL 593
              VRV TV  G  +T ++
Sbjct: 176 AFNVRVNTVNPGVINTQMM 194


>UniRef50_Q82FK0 Cluster: Putative dehydrogenase; n=2;
           Streptomyces|Rep: Putative dehydrogenase - Streptomyces
           avermitilis
          Length = 584

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 55/194 (28%), Positives = 97/194 (50%), Gaps = 9/194 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS-D 206
           ++V +TGA +GIG +      + G + +A+   AE A ++   E++   G    +  + D
Sbjct: 317 QLVLVTGAGSGIGRATAYAFAEAGARVVAVDRNAEGAART--AEMSRLIGAPDAWAETVD 374

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTL 368
           V+DE+    +   V  E G +DV++NNA +       + +   ++K ++VN+  +I    
Sbjct: 375 VSDEQAMEKLAEKVATEYGVVDVLVNNAGIGLSGSFFDTTAEDWRKVLDVNLWGVI---- 430

Query: 369 KAIEIMGKHSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
               + GK     G+GG ++N +S AA   S  +P Y  +K+AVL  S C+ R E  +  
Sbjct: 431 HGCRLFGKQMAERGQGGHIVNTASAAAYQPSKALPAYSTSKAAVLMLSECL-RAE-LAGQ 488

Query: 543 GVRVLTVCFGATDT 584
           G+ V  +C G   T
Sbjct: 489 GIGVSAICPGFVHT 502


>UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2;
           Bacteria|Rep: Short-chain dehydrogenase -
           Symbiobacterium thermophilum
          Length = 254

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 60/194 (30%), Positives = 90/194 (46%), Gaps = 6/194 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  ITGAA G+G +   +   EG + + I D+ EE G++ Q       G    F R+DV
Sbjct: 7   KVAIITGAAMGMGAATAELFAREGAR-VVIADLNEELGRA-QARKIQDAGGAAAFVRADV 64

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 389
           +       ++   V   G +DV +NNAA   D+  +     E    A+I   LK + +  
Sbjct: 65  SRAGDVEAMVQFAVDTFGRLDVAVNNAAHSPDTRPL-ADLDEAVWDAVIGVDLKGVALCL 123

Query: 390 KHS------GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           K+        G GG++IN+SSV+ +      P Y A K  V+  +        +S  G+R
Sbjct: 124 KYELRQMLKQGGGGSIINISSVSGIRPQPGTPAYVAAKHGVIGLTKQAAM--DYSPHGIR 181

Query: 552 VLTVCFGATDTALL 593
           V  V  GA DT +L
Sbjct: 182 VNAVAPGAVDTPML 195


>UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii
           KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain
           KSM-K16)
          Length = 247

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 64/207 (30%), Positives = 102/207 (49%), Gaps = 7/207 (3%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
           E  +KVV ITG A+GIG + V   L +G K + I D  +E G++   EL    G +  F 
Sbjct: 3   ELTNKVVIITGGASGIGRAAVDAFLAKGAK-VVIADFNKETGEAAVKELTDA-GKQVLFV 60

Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDS----IGIYKKAIEVNVTALIT 359
           ++DV++E     ++   V+    +D++INNA    M+ S       Y+K ++V    +  
Sbjct: 61  QTDVSNEPSVQNMVAETVKAYERVDILINNAGFGTMSPSHERTYEDYEKIVKVCQDGVFL 120

Query: 360 STLKAIEIMGKHSGGKGGTVINVSSV-AALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
            +  AI+ M K     GG +IN SS+  ++ Q   +P Y A K AV   +  +     ++
Sbjct: 121 GSKHAIKEMIKTG---GGCIINTSSILGSVAQPEALP-YNAAKGAVNTMTKSLA--VEYA 174

Query: 537 KTGVRVLTVCFGATDTALLTDEKLGTF 617
              +RV  V  G  +TA +  E LG F
Sbjct: 175 DKQIRVNAVAPGFVETAAVNKEALGDF 201


>UniRef50_Q46PX5 Cluster: NAD-dependent
           epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR; n=2; Bacteria|Rep:
           NAD-dependent epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR - Ralstonia eutropha (strain
           JMP134) (Alcaligenes eutrophus)
          Length = 253

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 58/197 (29%), Positives = 97/197 (49%), Gaps = 7/197 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           KDKV  +TG A+GIGE+ VR+   +G   + I D     G+ L  EL S+      +   
Sbjct: 9   KDKVAIVTGGASGIGEATVRLFASQGAS-VVIAD-RSALGEKLAREL-SESSLAAHYSEV 65

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 362
           DV+ E+    +++  V   G +D+++ NA + + S  +       +++ I+VN+T +  S
Sbjct: 66  DVSREDDTRRLIDDTVSRFGRLDIMVANAGIAHPSAPVEDVSVEQWQQMIDVNLTGVFLS 125

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
              AI  M K   G GG ++N++S+           Y A K  V+  +  +G   H ++ 
Sbjct: 126 NKLAIVQMKKQ--GTGGAIVNMASILGHVGMPGAASYNAAKGGVVNLTRSLG-VSH-AQD 181

Query: 543 GVRVLTVCFGATDTALL 593
           G+RV  VC G   T L+
Sbjct: 182 GIRVNAVCPGFVATPLI 198


>UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Mesorhizobium sp. BNC1|Rep: Short-chain
           dehydrogenase/reductase SDR - Mesorhizobium sp. (strain
           BNC1)
          Length = 257

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 56/192 (29%), Positives = 94/192 (48%), Gaps = 5/192 (2%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS-D 206
           KV  +TGAA G+GE++   L  +G + +A+LD+ +E G  +   +    GN   +YR+ D
Sbjct: 7   KVALVTGAARGLGEAIAVELAAQGAR-VALLDVLDELGAEVAENIKKSSGN--AYYRNCD 63

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEV--NVTALITSTLKAI- 377
           + D E     ++ V    G +DV++NNAA+      I + + E   N+  +  S++    
Sbjct: 64  IRDTEEVRSAVDEVYSTYGKLDVLVNNAAVSTAPTSIPELSEETWNNIFNVNVSSIYRFC 123

Query: 378 -EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
             ++ +     GG VIN+SSV           Y ATK A++  S  +     + +  +RV
Sbjct: 124 RFVLPRMQEAGGGAVINMSSVHQSHSLTGWTAYAATKGAIISMSRQLA--AEWGRFNIRV 181

Query: 555 LTVCFGATDTAL 590
            TV  GA D  +
Sbjct: 182 NTVSPGAIDATM 193


>UniRef50_A0HI81 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Comamonas testosteroni
           KF-1
          Length = 259

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           +   ITGA  GIG +   +   EG   + +   AE   ++ +  L +  G +     +DV
Sbjct: 9   RTALITGAGAGIGAAASHLFCKEGAAVLMVDANAEALERTREAILQAVPGARLACVMADV 68

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE------VNVTALITSTLK 371
           +DE      +   VQ+ GG+D ++NNAA+ N S      A E      VN+  +      
Sbjct: 69  SDESAAAAAVGQCVQQWGGLDTLVNNAAMRNYSAAADATAAEWQAMVGVNLVGMSNYCRA 128

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           A+  + + SG   G+++NVSS  A+T    M +Y ATK+A L ++  +   E  +  GVR
Sbjct: 129 ALPAL-RQSG--TGSIVNVSSCYAVTGRKGMALYDATKAAQLAYTRSLAFEE--AAHGVR 183

Query: 552 VLTVCFGATDT 584
              VC G+T T
Sbjct: 184 ANAVCPGSTLT 194


>UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019;
           n=11; cellular organisms|Rep: Uncharacterized
           oxidoreductase TM_0019 - Thermotoga maritima
          Length = 256

 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 53/192 (27%), Positives = 96/192 (50%), Gaps = 6/192 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  +TG   GIG ++ ++  + G+K + I +I EEAG   +  L  + G    F ++DV
Sbjct: 5   KVAVVTGGGQGIGAAIAQLFAENGMK-VVIAEIDEEAGVEREEMLRER-GLDVTFVKTDV 62

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 371
            DE     ++   V+  GG+DV++NNAA+M+        +  +++ I VN+T     +  
Sbjct: 63  ADENSVKNMVRKTVEIYGGVDVLVNNAAVMSVKSIFERPLEEWERVIRVNLTGPYICSRY 122

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
             E M K     GG +IN++S  A         Y A+K  ++  ++ +      S+  +R
Sbjct: 123 CAEEMIKRG---GGVIINIASTRAFQSEPDTEPYSASKGGLVALTHSLA--VSLSRYHIR 177

Query: 552 VLTVCFGATDTA 587
           V+++  G  +T+
Sbjct: 178 VVSISPGWIETS 189


>UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=17; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier
           protein) reductase - Chromobacterium violaceum
          Length = 246

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 56/196 (28%), Positives = 95/196 (48%), Gaps = 6/196 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           K KV  ITG+A+GIG++     + EG   +A+ D+  +A K++  EL +  G +   Y+ 
Sbjct: 4   KGKVSIITGSASGIGKATAEKFVKEGAI-VAVCDLNPDAVKTVVDELKA-LGGEAYGYKV 61

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 365
           DVTD+     ++  +    G IDV++NNA ++ D+  I      + K I++N+  +    
Sbjct: 62  DVTDKGQIAEMVADLKNRCGRIDVLVNNAGIVQDAQLIKMSEDQFDKVIDINLKGVYNCA 121

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
              ++ M +     GG ++N SSV  +  +     Y A K  V+ F     +     K G
Sbjct: 122 RAVVDTMVEQG---GGVILNASSVVGVYGNFGQTNYAAAKFGVIGFVKTWAK--ELGKKG 176

Query: 546 VRVLTVCFGATDTALL 593
           +R   VC G   T +L
Sbjct: 177 IRANAVCPGFVATPIL 192


>UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Frankia sp. EAN1pec|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 250

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 48/169 (28%), Positives = 89/169 (52%), Gaps = 7/169 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  +TGAA GIG ++    + EG K + I DI +  G+ +  EL    G +  F+ +DV
Sbjct: 10  KVAIVTGAANGIGVAIATRFVTEGAK-VVIADI-DAGGQGVAAEL----GERATFFSTDV 63

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNVTALITSTL 368
           +D      +++  ++  GG+ V+ NNA +       ++D +  +++ + V++  ++  + 
Sbjct: 64  SDPVQTQALVDFTIRHFGGLHVLCNNAGVSGGLRRFLDDDLRDFERVVAVDLYGVMACSR 123

Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 515
            A   M  H GG    ++N++S A +T    M  Y A K+ V+QF+ C+
Sbjct: 124 SAARHMVDHGGG---AIVNIASGAGITPGIGMLPYRAAKAGVVQFTRCL 169


>UniRef50_Q15Q07 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Gammaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Pseudoalteromonas
           atlantica (strain T6c / BAA-1087)
          Length = 270

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 60/198 (30%), Positives = 97/198 (48%), Gaps = 9/198 (4%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           K KV+ ITG ATGIG  +V   + +  + +  +D+ EEA  +L  +L+++ G    F   
Sbjct: 26  KGKVILITGGATGIGAVMVEAFMRQQAR-VLFVDVQEEAAHALCSKLHAELGAAPIFKNL 84

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITS 362
           D T  +     ++++    G +DV+INN A       L  D  G ++  + VN+ +   +
Sbjct: 85  DTTHIDELQAFISSIGHSHGRLDVLINNVANDTRHSPLDIDQQG-WRDCMAVNLDSTFFA 143

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
              AI +M      + G +IN+SS+  L     MP Y A KSA+   S  +     + + 
Sbjct: 144 CQSAIRLM---RDKRTGNIINMSSINVLIGPKQMPGYVAAKSALNGLSKSLA--NQYGEY 198

Query: 543 GVRVLTVCFG--ATDTAL 590
           G+RV T+  G  ATD  L
Sbjct: 199 GIRVNTILPGWVATDRQL 216


>UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=4; Shewanella|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Shewanella sp.
           (strain ANA-3)
          Length = 292

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 53/200 (26%), Positives = 97/200 (48%), Gaps = 7/200 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEA-GKSLQVELNSKYGNKTKFYR 200
           K KV  ITG+ +GIG +   +L ++G  H+ +  +  EA G+ L  E   +Y   T F  
Sbjct: 35  KGKVGLITGSTSGIGLATAHVLAEQGC-HLILHGLMPEAEGRRLAAEFAEQYHIHTYFSN 93

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITS 362
           +D+ D E     ++A V+  G ID+++NNA + +        I  +   I +N+++   +
Sbjct: 94  ADLRDPESIHAFMDAGVKALGSIDILVNNAGIQHTENVAHFPIDKWNDIIAINLSSAFHT 153

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
             +A+  M +    + G +IN++SV  L  S     Y A K  ++  +  +      ++ 
Sbjct: 154 IQQAVPAMAEK---RWGRIINIASVHGLVASVNKAAYCAAKHGIVGLTKVVA--IECAEQ 208

Query: 543 GVRVLTVCFGATDTALLTDE 602
           G+ V  +C G  DT L+  +
Sbjct: 209 GITVNAICPGWVDTPLINKQ 228


>UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=2;
           Euryarchaeota|Rep: Predicted short chain dehydrogenase -
           Methanosphaera stadtmanae (strain DSM 3091)
          Length = 253

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 58/206 (28%), Positives = 95/206 (46%), Gaps = 7/206 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           K KV  ITGA  GIG+S+  +  +EG   I I    E   + +  E+NS  G+ +     
Sbjct: 4   KGKVAIITGATAGIGKSIAYLFAEEGASTILIARRKERL-EQITNEINSNGGDASACI-G 61

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 362
           DVT +E    ++   + + G ID+++NNA +M+D + +       + K I+VN+T  +  
Sbjct: 62  DVTKQEDIDNVVKLALDKYGKIDIIVNNAGIMDDFVSVKHIDDDLWDKTIDVNLTGPMRL 121

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
               I  M K++   GG +I +SSV  L        Y A+K  V+  +        + K 
Sbjct: 122 IRAVIPEMIKNN---GGNIITISSVGGLIGKISGAAYTASKHGVIGLAKHTAWV--YGKH 176

Query: 543 GVRVLTVCFGATDTALLTDEKLGTFD 620
            +R   +  G  +T + T    G  D
Sbjct: 177 NIRSNVIAPGTVNTEIATTINPGRMD 202


>UniRef50_Q71R50 Cluster: Dehydrogenase/reductase SDR family member
           11 precursor; n=7; Eukaryota|Rep:
           Dehydrogenase/reductase SDR family member 11 precursor -
           Gallus gallus (Chicken)
          Length = 255

 Score = 77.0 bits (181), Expect = 4e-13
 Identities = 54/196 (27%), Positives = 95/196 (48%), Gaps = 8/196 (4%)
 Frame = +3

Query: 21  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
           W  +V  +TGA+ GIG +V R L+  G+K +      ++  K      ++ Y      Y+
Sbjct: 4   WTGRVALVTGASVGIGAAVARALVQHGMKVVGCARSVDKIEKLAAECQSAGYPGTLIPYK 63

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITS 362
            D+++EE  L + +A+     G+DV INNA       L++     ++  I+VNV A+   
Sbjct: 64  CDLSNEEEILSMFSAIKTLHQGVDVCINNAGLARPEPLLSGKTEGWRTMIDVNVMAVSIC 123

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSV--AALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
           T +A + M K      G +IN++S+   ++    V+  Y ATK AV   +  + +    +
Sbjct: 124 TREAYQSM-KERNIDDGHIININSMNGHSVVPQSVVHFYSATKYAVTALTEGLRQELREA 182

Query: 537 KTGVRVLTVCFGATDT 584
           KT +R   +  G  +T
Sbjct: 183 KTHIRATCISPGLVET 198


>UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n=2;
           Proteobacteria|Rep: 2O-beta-hydroxysteroid dehydrogenase
           - Pseudoalteromonas haloplanktis (strain TAC 125)
          Length = 262

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 57/210 (27%), Positives = 102/210 (48%), Gaps = 6/210 (2%)
 Frame = +3

Query: 3   LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN 182
           +K +    +KV  +TGAA GIG ++ + L+D G   IA   + EE  +  Q     + G+
Sbjct: 1   MKNATHLTNKVALVTGAARGIGRAICQALVDSGATVIATDILTEELNQMAQ-----ELGD 55

Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNV 344
           K      DVTDE  +  I++A +++   ID+++NNA ++            ++K I++N+
Sbjct: 56  KVTPMTHDVTDELQWQSIVSATLEKHQKIDILVNNAGILLFATLETTEPQQFRKLIDINI 115

Query: 345 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 524
           T         I  M K +G   G ++N+SS +++  ++    Y A+K AV   +      
Sbjct: 116 TGTFLGLHSVIPCM-KKAG--SGAIVNISSASSILPNNGTGAYAASKYAVRGLTRTAAL- 171

Query: 525 EHFSKTGVRVLTVCFGATDTALLTDEKLGT 614
                 G+RV +V  GA +T +   + L +
Sbjct: 172 -ELGPFGIRVNSVHPGAVNTPMTNPQGLSS 200


>UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase;
           n=1; Burkholderia xenovorans LB400|Rep: Putative
           short-chain type dehydrogenase - Burkholderia xenovorans
           (strain LB400)
          Length = 252

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 62/199 (31%), Positives = 92/199 (46%), Gaps = 6/199 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           M+     K + ITGA   IG+   R  + EG + + I DIAEEAG+++  EL    G   
Sbjct: 1   MAGRLSGKRIIITGAIGNIGKEAARGFIAEGAR-VVIGDIAEEAGRAVAAEL----GAAA 55

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 368
            F + DVT E     ++   V+  GG+D +  NA L     G      + N  AL     
Sbjct: 56  HFVQVDVTSEASVANLIARGVEWLGGLDALAQNAGLQRS--GAIAGFEQANWDALFAVNA 113

Query: 369 KAIEIMGKHS------GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
           +A     KH+       GK G++IN+SS+A       +  Y A+K AV+ F+  +     
Sbjct: 114 RAHFFGAKHAIPHLQRSGK-GSIINMSSLAGKRGGPGLVAYSASKGAVIAFTTALAL--E 170

Query: 531 FSKTGVRVLTVCFGATDTA 587
            +   +RV  +C G  DTA
Sbjct: 171 LAPDNIRVNAICPGWVDTA 189


>UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8;
           Bacteria|Rep: Short-chain alcohol dehydrogenase -
           Burkholderia dolosa AUO158
          Length = 284

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 58/195 (29%), Positives = 100/195 (51%), Gaps = 7/195 (3%)
 Frame = +3

Query: 27  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
           +KVV ITGA++GIGE+  ++L  +G   +A+     +  + +  E+ +K G +   ++ D
Sbjct: 44  NKVVVITGASSGIGEATAKLLASKGAT-VALAARRLDKLQRVAAEIVAK-GGQVSVHQVD 101

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS-IGIYK-----KAIEVNVTALITSTL 368
           VTD+E    ++N VV + G +DV++NNA LM  + + + K     + I++N+  L+    
Sbjct: 102 VTDQEQVNRLINDVVSQHGRLDVMVNNAGLMAIAPLSLRKTDEWDRMIDINIKGLLYGVA 161

Query: 369 KAIEIMGKHSGGKGGTVINVSSVAAL-TQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
            A+ +  K    + G  +N++SV  L   S    +Y  TK AV   S  +    H     
Sbjct: 162 AALPVFEKQ---QSGHFVNIASVVGLKVFSPGGTVYSGTKFAVRAISEGL---RHEVGGN 215

Query: 546 VRVLTVCFGATDTAL 590
           +R   +  GA DT L
Sbjct: 216 IRTTVISPGAIDTEL 230


>UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=19; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 246

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 56/193 (29%), Positives = 92/193 (47%), Gaps = 6/193 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K+  +TGA  GIG+++   L  EG   + + D+  +A K     L+    +      +DV
Sbjct: 7   KIAVVTGAGQGIGKAIATKLAAEGAT-VVVTDVDHQAAKETAAALD----HGAIGLHADV 61

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITSTLK 371
           TD      +++ VV   G IDV++NNA      A ++     + + I +N+  ++ ++ K
Sbjct: 62  TDRTSVDAMVDEVVATFGRIDVLVNNAGWDKGEAFVDSEPETWDRIIGINLYGVLNTSKK 121

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
            + IM        G+V+N+ S A    S    +Y A K  V+ FS    R    +++ V 
Sbjct: 122 VLPIMAAQG---SGSVVNIGSDAGRVGSSGEAVYSAAKGGVIAFSKATAR--EMARSQVN 176

Query: 552 VLTVCFGATDTAL 590
           V  VC G TDTAL
Sbjct: 177 VNCVCPGPTDTAL 189


>UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Rep:
           Short chain dehydrogenase - Mycobacterium avium (strain
           104)
          Length = 594

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 56/195 (28%), Positives = 92/195 (47%), Gaps = 6/195 (3%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
           E + ++  +TGA  GIG +    L  +G + + I+D  + A      +     G     Y
Sbjct: 322 EVRGRLALVTGAGAGIGRATAVELARQGARKVVIVD-RDRAAADQTADAVRAAGAGAAVY 380

Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 377
           + DV+DE     +   V  E G +D+++NNA +     G + +    N  A++   ++ +
Sbjct: 381 QVDVSDEAAMNDLAAQVRNEHGVVDILVNNAGI--GMAGRFLETSPANWDAIMGVNVRGV 438

Query: 378 EIMGKHSG------GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
               +  G      G+GGT+INV+S AA   S  M  Y  TK+AVL  S  + R + F+ 
Sbjct: 439 IWGSRAFGAQMVERGQGGTIINVASAAAYLPSKSMVAYGTTKAAVLALSESL-RAD-FAD 496

Query: 540 TGVRVLTVCFGATDT 584
            G+ V  VC G  +T
Sbjct: 497 EGITVTAVCPGFVNT 511


>UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=2; Thermotoga|Rep:
           Oxidoreductase, short chain dehydrogenase/reductase
           family - Thermotoga maritima
          Length = 257

 Score = 76.2 bits (179), Expect = 7e-13
 Identities = 54/198 (27%), Positives = 94/198 (47%), Gaps = 8/198 (4%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           K KV  +TG   GIG+++ + L   G   + I+DI EE  +    E+  K G +  FY  
Sbjct: 11  KRKVALVTGGGQGIGKAIAQALAAAGAA-VLIMDINEETARRTVEEIKEK-GGEADFYVG 68

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 365
           DVT EE   G +   +   G +D+ +NNA +       N  +  +KK I+VN+  +  S 
Sbjct: 69  DVTKEEDCFGAVKKALDRWGKLDIGVNNAGIGDWCEAENYPVEKWKKVIDVNLVGVFLSA 128

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAA--LTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
                 M +   GK   +IN++S++   + +      Y A+K+ V+  +  +     ++ 
Sbjct: 129 KAEFHAMKERKYGK---IINIASMSGHIVNKPQKQTAYNASKAGVIHLTRSLA--AEWAP 183

Query: 540 TGVRVLTVCFGATDTALL 593
            G+RV ++  G   T L+
Sbjct: 184 YGIRVNSISPGYIRTPLI 201


>UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Bacillus sp. B14905
          Length = 254

 Score = 76.2 bits (179), Expect = 7e-13
 Identities = 54/195 (27%), Positives = 95/195 (48%), Gaps = 6/195 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           ++KV  ITG  TGIG+    +   EG K I I DI E++G     ++ + +G +  F   
Sbjct: 7   ENKVAVITGGGTGIGKETALLFAKEGAK-IVITDINEQSGNETVSDIQA-FGGEALFVLH 64

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 365
           DV++E+ +  + +  +     +D++ NNA       L    +  + + + +NVT +    
Sbjct: 65  DVSNEDDWKKVADEAIHTFNKVDILFNNAGIYIIKPLAEIELSDWNRLMSINVTGVFLGM 124

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
              + +M K +    G+VIN SS+A LT +    +Y A+K AV   +        ++  G
Sbjct: 125 KHIMPLMAKQN---KGSVINASSIAGLTGAAGHVLYGASKGAVRIMTK--DAAMEYAPYG 179

Query: 546 VRVLTVCFGATDTAL 590
           VRV ++  G  DT +
Sbjct: 180 VRVNSIHPGYIDTGM 194


>UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Candidatus Methanoregula boonei 6A8|Rep:
           Short-chain dehydrogenase/reductase SDR - Methanoregula
           boonei (strain 6A8)
          Length = 253

 Score = 76.2 bits (179), Expect = 7e-13
 Identities = 55/214 (25%), Positives = 100/214 (46%), Gaps = 6/214 (2%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV+ +TGA+ GIG +   +      + I       +  +SL  E+ +  G+     R+DV
Sbjct: 12  KVILVTGASRGIGRATAFLAAKNHAQVIVNYQKHADQAESLVSEITA-LGHSAMAIRADV 70

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITSTLK 371
           T EE    +   + ++ G +D+++NNA +M ++      I  Y+  ++VN       T  
Sbjct: 71  TCEEEVKEMFRQIREQYGRLDILVNNAGIMKNNLLMMTKIQEYQDVMDVNCKGTFLCTQH 130

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           A +IM +    K GT+IN++SV  +  +     Y ++KS V+ F+ C  +        + 
Sbjct: 131 AAKIMVRQ---KAGTIINLASVVGVYGNRGQSAYASSKSFVIGFTKCAAK--ELGAFNIT 185

Query: 552 VLTVCFGATDTALLTDEKLGTFDKYLESSCLDQL 653
           V  V  G  DT L  D +    +  L++  L ++
Sbjct: 186 VNAVAPGFIDTDLTADTRSQVKEDILKNIALGRI 219


>UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
           Short-chain dehydrogenase/reductase SDR - Candidatus
           Nitrosopumilus maritimus SCM1
          Length = 253

 Score = 76.2 bits (179), Expect = 7e-13
 Identities = 51/173 (29%), Positives = 95/173 (54%), Gaps = 10/173 (5%)
 Frame = +3

Query: 27  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
           DKV  +TGA++ IG+ + +  ++EG K I I    E   ++ + E+ ++  + T     D
Sbjct: 5   DKVAIVTGASSDIGKGIAKKFVEEGAKVILIARNLEGL-ENTRKEIGNE--DSTAAMTCD 61

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALITST 365
           + DE   L ++N ++   G ID+++NNA  +ND I  +       +K I VN+  +   T
Sbjct: 62  LVDESQTLQVVNQIMDTYGKIDILVNNAGAINDPIHFHEMQNSEIQKLINVNLLGVFNMT 121

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVA---ALTQSHVMPIYFATKSAVLQFSNCI 515
            KA  ++ K +  K G+++N+ S++   A+ + H + +Y ATK+A+  F+  I
Sbjct: 122 -KA--VLTKMADVKSGSIVNIGSISSERAIPRVH-LAVYSATKAAIPMFTKSI 170


>UniRef50_Q97EW4 Cluster: Predicted short-chain dehydrogenase; n=6;
           Clostridium|Rep: Predicted short-chain dehydrogenase -
           Clostridium acetobutylicum
          Length = 262

 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 52/188 (27%), Positives = 94/188 (50%), Gaps = 5/188 (2%)
 Frame = +3

Query: 36  VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 215
           V ITGA+TGIG  + RI    G  +  ++   +E  K L +EL      K    + D++ 
Sbjct: 3   VLITGASTGIGYEITRIFARNG--YDVVITARDE--KRL-IELAKNINTKVTVIKKDLSR 57

Query: 216 EEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKH 395
            +    + N + +    +D+++NNA  M D+ G++ K+    +  ++   +K++ I+ + 
Sbjct: 58  PDSANELFNEIKENNIEVDILVNNAG-MGDT-GLFHKSSVDKINEMLELNIKSLTILTRL 115

Query: 396 SGG-----KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
                   + G ++NV+S  +      + +Y+ATK+ VL F+  IG  E   K  V+V  
Sbjct: 116 VSAEMVKKRSGMILNVASTGSYMPGPFIAVYYATKAYVLSFTEAIG--EELKKFNVKVSA 173

Query: 561 VCFGATDT 584
           +C GAT T
Sbjct: 174 LCPGATAT 181


>UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein)
           reductase; n=6; Desulfuromonadales|Rep: 3-oxoacyl-(Acyl
           carrier protein) reductase - Geobacter sulfurreducens
          Length = 246

 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 58/214 (27%), Positives = 99/214 (46%), Gaps = 5/214 (2%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
           E+KD +V +TG   GIG ++      +G    A     +EA ++L+ E     G+     
Sbjct: 2   EFKDSIVVVTGGTRGIGRAISLHFARQGALVTAAYRADDEAARALEAEAAGLPGS-IAVI 60

Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 377
           R+DV   E  + +++A   E G + V++NNA ++ D  G      E +  A++ + L  +
Sbjct: 61  RADVGTAEGAMAVIDAASGESGTLHVLVNNAGIIRD--GYLAMMAEDDWDAVMRANLSPL 118

Query: 378 EI-----MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
                  + K    + G +IN+SSV+A   +     Y ATK A + F+  + R       
Sbjct: 119 FHCCKWGVRKMLARRRGAIINLSSVSAFAGTAGQTNYAATKGAAVSFTKSLAR--EVGPL 176

Query: 543 GVRVLTVCFGATDTALLTDEKLGTFDKYLESSCL 644
           G+RV  V  G  +T ++   K    D+ + SS L
Sbjct: 177 GIRVNAVAPGLIETEMIAGMKREMVDRIVGSSIL 210


>UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=2; Staphylococcus
           epidermidis|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family - Staphylococcus
           epidermidis (strain ATCC 35984 / RP62A)
          Length = 255

 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 53/188 (28%), Positives = 100/188 (53%), Gaps = 7/188 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  + G ATGIG+++   L   G  +I I D+    G+     ++++ G KT   + D+
Sbjct: 13  KVAMVIGGATGIGKAMAEALAQAGA-NIVIADLQSNIGQETATTISTQSGVKTTSLKLDI 71

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNA--ALMNDSIGI-YKKAI-EVNVTALITSTLKAI 377
           T  +    I++ VV+E G ID+++NNA  ++ +D+  I Y++ + E+N++  +       
Sbjct: 72  THSDEVNQIVDYVVREYGKIDILVNNASISIQDDTENISYEEWLKEINLS--LNGAFSVA 129

Query: 378 EIMGKHSGGKG-GTVINVSSVAAL--TQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
           + +G+    KG G++INVSSV  L   ++     Y  +K+ V   +  + R   +S+ G+
Sbjct: 130 QTVGRQMIEKGSGSIINVSSVLGLIANKTQDQSSYETSKAGVTMLTKSLAR--EWSRYGI 187

Query: 549 RVLTVCFG 572
           +V  +  G
Sbjct: 188 KVNAIAPG 195


>UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reductase;
           n=3; Proteobacteria|Rep: 3-ketoacyl-acyl carrier protein
           reductase - Pseudoalteromonas haloplanktis (strain TAC
           125)
          Length = 247

 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 59/203 (29%), Positives = 98/203 (48%), Gaps = 6/203 (2%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           M H+  D+VV +TGA  GIG+S+V      G  ++A +DI  +   +   ELN+      
Sbjct: 1   MKHQ--DQVVLVTGAGQGIGQSIVSYFATAGA-NVAAVDINADTLNASVNELNANVAGNI 57

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 350
               +++   +     + AVV++ G +D +IN A      A ++     + K I VN+T 
Sbjct: 58  VAITANIAKSDSVRDAIAAVVEKFGRLDAIINVAGVGSIDAFVDTPDEHWDKVIAVNLTG 117

Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
                 +A ++M        G +INVSS AALT       Y A+K+ V+  +  + R   
Sbjct: 118 TFLCCREAAKVMQAQG---SGCIINVSSTAALT-GEGPSHYCASKAGVMGLTRSMAR--E 171

Query: 531 FSKTGVRVLTVCFGATDTALLTD 599
            +  G+RV T+  G T+T ++ D
Sbjct: 172 LAPVGIRVNTIVPGPTNTPMMAD 194


>UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia sp. (strain
           383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
           / R18194))
          Length = 262

 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 48/164 (29%), Positives = 83/164 (50%), Gaps = 7/164 (4%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           + KV  ITG A GIG    R L   G   +AILD+  +  ++L  E+ ++ G +  F+  
Sbjct: 11  RGKVAAITGGARGIGAETARTLAAAGAS-VAILDVLSQPAEALVEEIRAQ-GGQAAFWSL 68

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITS 362
           DVT E     +   +V   G +DV++NNA +   ++         +++ ++VNV  +   
Sbjct: 69  DVTHEADVARVFGEIVAHFGRLDVLVNNAGIEGHNVPTHELTLAQWQRVLDVNVNGVFLC 128

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 494
           T  AI  +       GG+++N+SS+  +     +P Y A+K+AV
Sbjct: 129 TRAAIPHI---DAAGGGSIVNLSSMYGIVGGPDVPAYHASKAAV 169


>UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Rhodopseudomonas palustris BisB5|Rep: Short-chain
           dehydrogenase/reductase SDR - Rhodopseudomonas palustris
           (strain BisB5)
          Length = 263

 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 7/195 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           +VV +TG A+GIG +       +G   + + DI +  G    VE   + G++ ++ R+DV
Sbjct: 21  RVVLVTGGASGIGRAAALAWARQGCS-VLVADIDDRGGAET-VEAIERLGSRARYQRNDV 78

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 368
           TDE     ++   V   G +DV  NNA +   S  I       ++  I VN+  +  S  
Sbjct: 79  TDERECASLVEQAVLHFGRLDVAFNNAGITGPSAYIANYPGADWRHVINVNLLGIFNSMQ 138

Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
             + +    S G  G ++N +SV  L        Y A K  V+  + C      + ++G+
Sbjct: 139 PQLRLF--ESQG-AGVIVNTASVIGLRGVAGGSAYAAAKHGVIGLTKCAAL--EYGRSGI 193

Query: 549 RVLTVCFGATDTALL 593
           R+  VC G  +T L+
Sbjct: 194 RINAVCPGYIETPLV 208


>UniRef50_O86553 Cluster: Putative dehydrogenase; n=1; Streptomyces
           coelicolor|Rep: Putative dehydrogenase - Streptomyces
           coelicolor
          Length = 276

 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 54/197 (27%), Positives = 99/197 (50%), Gaps = 7/197 (3%)
 Frame = +3

Query: 15  HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF 194
           HE+ +    +TGA+ G+GE+  R L   G  H+ ++  + +A  +L  E+ + +  +   
Sbjct: 2   HEYTNTTALVTGASKGLGEAYARELASRGA-HLVLVARSADALHALADEIRATHSVRVDV 60

Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALI 356
             +D++D      +L+AV      +D+++NNA +      +   +    ++++VNVTAL+
Sbjct: 61  IAADLSDRRSPQRVLDAVDGLGLDVDLLVNNAGMGAVGPFLVRPLAPNLQSVDVNVTALV 120

Query: 357 TSTLKAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533
                 + ++G     +G G ++N++S AA         Y ATK+ VL F+  +   E  
Sbjct: 121 ----GLVHLLGARMVERGRGGIVNIASTAAFQPMPYQASYAATKAFVLSFTEAVA--EEV 174

Query: 534 SKTGVRVLTVCFGATDT 584
             TGVRV+    GAT T
Sbjct: 175 RGTGVRVMAAHPGATAT 191


>UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase,
           putative glucose-1-dehydrogenase; n=1; Pyrococcus
           abyssi|Rep: Short-chain alcohol dehydrogenase, putative
           glucose-1-dehydrogenase - Pyrococcus abyssi
          Length = 240

 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 58/202 (28%), Positives = 98/202 (48%), Gaps = 7/202 (3%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
           E K KV  ITGA+ GIG ++   L   GV  +      EE  K  + EL  +YG +T   
Sbjct: 2   ELKGKVALITGASRGIGRAIAIELAKRGVNVVINYRSNEEEAKKTE-ELCRQYGVETLLV 60

Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM---NDSIGI----YKKAIEVNVTALI 356
           ++DV++ E    ++  V+ + G ID++INNA ++    D + +    + + I VN+    
Sbjct: 61  KADVSNREEVREMVKKVIDKFGRIDILINNAGILGKTKDPLEVTDEEWDRVISVNLKGAF 120

Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
             T + +  M      K G ++N++S+A      V P Y A+K  ++  +  + R  H +
Sbjct: 121 IVTQEVLRYM------KKGKIVNIASIAGKDGGTVGPHYAASKGGLIALTFNLAR--HLA 172

Query: 537 KTGVRVLTVCFGATDTALLTDE 602
              + V  V  G  DT +L+ E
Sbjct: 173 -PNILVNAVAPGPVDTDMLSSE 193


>UniRef50_Q1Q261 Cluster: Strongly similar to
           3-oxoacyl-[acyl-carrier protein] reductase; n=1;
           Candidatus Kuenenia stuttgartiensis|Rep: Strongly
           similar to 3-oxoacyl-[acyl-carrier protein] reductase -
           Candidatus Kuenenia stuttgartiensis
          Length = 239

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 55/215 (25%), Positives = 106/215 (49%), Gaps = 7/215 (3%)
 Frame = +3

Query: 36  VFITGAATGIGESVVRILLDEG----VKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           + +TG + GIG+++ ++ + EG    V H   +D  E+    L+ E +S  G+ +   ++
Sbjct: 1   MLVTGGSKGIGKAICKVFIGEGDHVIVNHCKPIDDIEK----LREEFSSPQGSFS-IEKA 55

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAI 377
           DVTD      +++ +V++ G IDV+INNA ++ D   +   A + N  +   +T      
Sbjct: 56  DVTDYAQIKQMVDNIVKKHGKIDVLINNAGIIKDGYIMLMSAKDWNDVINVNLTGVFNCT 115

Query: 378 EIMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
           + + +H  G + GT+IN++S++ +T       Y A K  V+ F+  + +    +   +RV
Sbjct: 116 KAVSEHMIGQRSGTIINIASLSGITGLPGQTNYSAAKGGVIAFTMALSK--ELAPFCIRV 173

Query: 555 LTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKK 659
            TV  G  +T ++        + Y E   L +  K
Sbjct: 174 NTVAPGVIETDIIDSLDKNKRNSYKEHIPLKRFGK 208


>UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4;
           Legionella pneumophila|Rep: Acetyoacetyl CoA reductase -
           Legionella pneumophila (strain Corby)
          Length = 248

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 50/172 (29%), Positives = 84/172 (48%), Gaps = 7/172 (4%)
 Frame = +3

Query: 27  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE-EAGKSLQVELNSKYGNKTKFYRS 203
           + VV ITG    IG +V +  LD   KH+  LD+   + G+    +L ++      F   
Sbjct: 4   NNVVLITGGTGDIGTAVAK-QLDSTFKHVIALDLVSYDEGEVWLHDLKTQGYKNINFRHM 62

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 365
           DVTD E    ++  +++E GGIDV+INNA +  D++        + + + VN+  +   T
Sbjct: 63  DVTDYEQCAEVIGLIIEEFGGIDVLINNAGITRDAVFTKMTKRQWDEVLRVNLDGMFNVT 122

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 521
            + +E M     G+   ++NVSSV A         Y A+K+ V  F+  + +
Sbjct: 123 KQVVESMKVQESGR---IVNVSSVNAQKGQFSQANYAASKAGVYGFTKSLAQ 171


>UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=1;
           marine gamma proteobacterium HTCC2143|Rep: Short-chain
           dehydrogenase/reductase - marine gamma proteobacterium
           HTCC2143
          Length = 264

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 58/200 (29%), Positives = 102/200 (51%), Gaps = 6/200 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           M++  + KV  ITG  +GIGE+   I + EG   + +   +EE G+++     ++ G+K 
Sbjct: 1   MTNRLQGKVAIITGGTSGIGEATADIYIKEGAT-VVLTGRSEEKGQAIA----NRLGDKA 55

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA----ALMNDSI--GIYKKAIEVNVTA 350
            + ++DV+ EE     ++  V+  G +DV+ NNA        DSI  G     +++ +++
Sbjct: 56  HYIKADVSKEEDIANTISETVERFGKLDVLFNNAGGPVGGTIDSIAPGDINYGVDLLLSS 115

Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
           ++     AIE M K +G  GG +IN +S+AA+       +Y A K+AV  ++   G    
Sbjct: 116 VVLGIRYAIEPM-KANG--GGVIINNTSIAAIRYRQGNLLYSALKAAVTHYTKLAG--VE 170

Query: 531 FSKTGVRVLTVCFGATDTAL 590
               G+RV  +  GA  T +
Sbjct: 171 LGPLGIRVNCISPGAIATPI 190


>UniRef50_A0X2J5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Shewanella pealeana ATCC 700345|Rep: Short-chain
           dehydrogenase/reductase SDR - Shewanella pealeana ATCC
           700345
          Length = 254

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 56/191 (29%), Positives = 99/191 (51%), Gaps = 6/191 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           MS     KV  ITGAA G+G +  R++  EG + + + DI  E GK    E+ +  GN +
Sbjct: 1   MSGRLIGKVALITGAARGVGLATARLMAREGAQ-VVLTDINAEQGK----EIANSIGNNS 55

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 350
            F   DVT E  +  ++N +  + G +++++NNAA++       +++  +++   VN  +
Sbjct: 56  LFIEHDVTKEADWSAVINHIEAKFGQLNILLNNAAILQLGDIKEETLAGWQRVHMVNSDS 115

Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
           +      A+ +M K SG  GG++IN+SS +A+        Y A+K+A+   S  +     
Sbjct: 116 VFLRIHYALPLMEK-SG--GGSIINMSSSSAVFGMPHFAAYGASKAAIRGLSQSVAVYCS 172

Query: 531 FSKTGVRVLTV 563
            +K  VR  T+
Sbjct: 173 QTKNNVRCNTL 183


>UniRef50_Q9FX95 Cluster: ARP protein; n=8; Magnoliophyta|Rep: ARP
           protein - Arabidopsis thaliana (Mouse-ear cress)
          Length = 629

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 67/227 (29%), Positives = 108/227 (47%), Gaps = 20/227 (8%)
 Frame = +3

Query: 42  ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGK---SLQVELNSKYGNKTKF-----Y 197
           +TG A+GIG ++   L ++GV  + + D +EE G+   SL  E N+K+     F      
Sbjct: 11  VTGGASGIGRALCLALAEKGV-FVTVADFSEEKGQETTSLVREANAKFHQGLSFPSAIFV 69

Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN---------DSIGIYKKAIEVNVTA 350
           + DVT+    L   +  +   G +D+ INNA +           D    +K  I V++ A
Sbjct: 70  KCDVTNRGDLLAAFDKHLATFGTLDICINNAGISTPLRFDKDDTDGSKSWKHTINVDLIA 129

Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
           ++  T  AI+ M      K G +IN+ S A L    V PIY A+K+ V+ F+  +    +
Sbjct: 130 VVEGTQLAIKAMKAKQ--KPGVIINMGSAAGLYPMPVDPIYAASKAGVVLFTRSLA---Y 184

Query: 531 FSKTGVRVLTVC--FGATDTALLTDEK-LGTFDKYLESSCLDQLKKG 662
           + + G+R+  +C  F  TD A   D   L +   Y+    +D L KG
Sbjct: 185 YRRQGIRINVLCPEFIKTDLAEAIDASILESIGGYMS---MDMLIKG 228


>UniRef50_UPI0000E465C5 Cluster: PREDICTED: similar to MGC80593
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to MGC80593 protein -
           Strongylocentrotus purpuratus
          Length = 258

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 55/186 (29%), Positives = 91/186 (48%), Gaps = 7/186 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           + V ITG+A G+G  + +     G + + +LDI  E  K L  EL SK G     Y  D+
Sbjct: 63  RTVLITGSANGLGRLLAQEFARRGAQ-LVLLDIDIEGNKLLAEELCSK-GRSAHAYYCDL 120

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 371
           + +     ++  + ++ G +D++INNAA ++       S    +K  EVN  A I  T  
Sbjct: 121 SRKTDLYSVIAQIKRDIGHVDILINNAATLSGKPVLQCSDSAIEKVFEVNTMAYIWLTKA 180

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG-RPEHFSKTGV 548
            +  M      K G V+N++S+A     + +  Y A+KSA++ F+  +G   +    TGV
Sbjct: 181 LLPDMLNR---KQGHVVNIASLAGFVGVNGLADYCASKSAIIGFTEALGYELKQMKATGV 237

Query: 549 RVLTVC 566
            +  VC
Sbjct: 238 HLSLVC 243


>UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -
           Rhizobium meliloti (Sinorhizobium meliloti)
          Length = 249

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 58/194 (29%), Positives = 99/194 (51%), Gaps = 7/194 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K+  +TGA++GIG +    L + G K + I     +  + L+ ++ +K G +      DV
Sbjct: 7   KIALVTGASSGIGAATAAKLAEAGAK-VGIAARRTDKLEDLKKKIEAK-GGEALVIEMDV 64

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALM--ND----SIGIYKKAIEVNVTALITSTLK 371
            D       +  +V   G ID+++NNA LM  +D     +  +++ ++VNV  L+ +T  
Sbjct: 65  VDTTSVEAGVKKLVDAYGSIDILVNNAGLMPLSDIDQFKVDEWQRMVDVNVKGLLNTTAA 124

Query: 372 AI-EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
            + +++ +HS    G V N+SS+A       + +Y ATK AV  FS+ + R E   K G+
Sbjct: 125 VLPQMIKQHS----GHVFNMSSIAGRKVFKGLSVYCATKHAVTAFSDGL-RMEVGQKHGI 179

Query: 549 RVLTVCFGATDTAL 590
           RV  +  GA  T L
Sbjct: 180 RVTCIQPGAVATEL 193


>UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein)
           reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl-carrier
           protein) reductase - Leptospira interrogans
          Length = 259

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 52/199 (26%), Positives = 100/199 (50%), Gaps = 7/199 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAAT--GIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN 182
           MS +++ KV  +TGAA+  G+G ++   +  EG   I ++D+ +E  +    ++  ++G 
Sbjct: 5   MSKQFEGKVALVTGAASPRGLGRAIANTIAKEG-GDIVLVDLNKEQIEQAAADVAKEFGV 63

Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITS 362
           KT     +VT  E    ++  V ++ G +D ++NNA ++ D++ I  +  E     ++  
Sbjct: 64  KTLGLSCNVTKPEDCDSVIAGVKEKFGKLDFLVNNAGVLKDNLFI--RMSEQEFDFVLDV 121

Query: 363 TLKAIEIMGKHSG-----GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527
            LK + +M K++       + G ++N+SSV+ LT       Y ++K+ V+  +    R  
Sbjct: 122 NLKGVFLMTKYASKLLLKAESGRIVNISSVSGLTGQPGQANYSSSKAGVIALTKVAAR-- 179

Query: 528 HFSKTGVRVLTVCFGATDT 584
            F+   V V  VC G   T
Sbjct: 180 EFAGRNVLVNAVCPGYVQT 198


>UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii
           KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain
           KSM-K16)
          Length = 257

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 53/189 (28%), Positives = 101/189 (53%), Gaps = 8/189 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K   +TG A G+G ++ + L   G   IAI+DI  EA      E+ + Y   T+  ++DV
Sbjct: 12  KHAVVTGGAQGLGFTIAKSLAAFGCD-IAIVDIDAEAAAKAAQEITTTYSVNTQSIQADV 70

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMN--DSIGI----YKKAIEVNVTALITSTLK 371
           + EE    +++ V++    IDV++NNA ++   D++ +    +K+ ++VN+ AL  ++ +
Sbjct: 71  SKEEEVSAMVDRVLESFPQIDVLVNNAGIVKKIDTLDMTYSDWKRTMDVNINALFLTSKQ 130

Query: 372 AIEIMGKHSGGKG-GTVINVSSVAA-LTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
               +GKH    G G+++N+SS++A +        Y A+K AV   +  +     +++ G
Sbjct: 131 ----VGKHMVANGSGSIMNMSSMSAMIANREAQSAYNASKGAVSMLTKSLA--SEWAQYG 184

Query: 546 VRVLTVCFG 572
           +RV  +  G
Sbjct: 185 IRVNAIAPG 193


>UniRef50_Q2JG54 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=3; Frankia|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Frankia sp.
           (strain CcI3)
          Length = 291

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 58/195 (29%), Positives = 92/195 (47%), Gaps = 4/195 (2%)
 Frame = +3

Query: 42  ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTDEE 221
           ITGA++GIG +      D G + + +   +E     +   L ++YG +      D+ DE 
Sbjct: 14  ITGASSGIGAAFAEAYADRGARLVLVAP-SEPRLWMVAERLGARYGTEAHVIAVDLADER 72

Query: 222 HFLGILNAVVQEQGGIDVVINNAALMN----DSIGIYKKAIEVNVTALITSTLKAIEIMG 389
               +  AV +    +D+++NNA          +   +   EV +  +    +  + + G
Sbjct: 73  GPDRLAEAVAEAGLEVDILVNNAGFGTRGPYHELSADRDHREVMLNVVAVERVAHLFLPG 132

Query: 390 KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTVCF 569
             + G+G TVINVSS +       M +Y A+K+ VL FS  IG    + + GVRVL +C 
Sbjct: 133 MVARGRG-TVINVSSTSGFQAVPYMTVYGASKAFVLSFS--IGLWAEYRRRGVRVLALCP 189

Query: 570 GATDTALLTDEKLGT 614
           G TDT     E LGT
Sbjct: 190 GPTDTEFF--EVLGT 202


>UniRef50_Q1IPJ3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain
           dehydrogenase/reductase SDR - Acidobacteria bacterium
           (strain Ellin345)
          Length = 261

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 60/196 (30%), Positives = 93/196 (47%), Gaps = 7/196 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           +D+VV ITG   GIG ++ R +  EG     I+   +E       +   + G     +  
Sbjct: 28  EDQVVLITGGNRGIGLAMARAVAKEGAS--VIITGRDEHTLHHAADQIKRDGGTVVSHVC 85

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITS 362
           DV DE+    +  A+ +    IDV++NNA L          S+  ++  IE N+T     
Sbjct: 86  DVRDEDSVDELFAAIHRHYSQIDVLVNNAGLAQRNAQVDHLSLEAWQACIETNLTGAFLC 145

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
           T  A+ +M       G TV+N  SVAA T    M  Y A+K+ +L F+N +   E     
Sbjct: 146 TRAALPMMSP-----GATVVNNVSVAANTAFPGMAAYSASKAGLLAFTNTL--REELRPR 198

Query: 543 GVRVLTVCFGATDTAL 590
           G+RV+++  GATDT +
Sbjct: 199 GIRVISLVPGATDTEI 214


>UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=4;
           Clostridiales|Rep: 7-alpha-hydroxysteroid dehydrogenase
           - Clostridium perfringens (strain SM101 / Type A)
          Length = 253

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 65/210 (30%), Positives = 99/210 (47%), Gaps = 10/210 (4%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           +S   K+KVV +TG   GIG + V+  LD G K +A+    +E       ELN    N  
Sbjct: 4   LSKSIKNKVVIVTGGTRGIGFATVKKFLDHGAK-VALCGSRKETVDKALEELNYINPNYD 62

Query: 189 KF-YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNV 344
              +  ++ D      +++ V+++ G ID++INNA  ++D+  IY        K I++NV
Sbjct: 63  AIGFYPNLLDSNEVKEMVDKVLEKWGTIDILINNAG-VSDNKSIYTQSDEDFSKIIDINV 121

Query: 345 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 524
            A+   T    EIM      K G ++N SSV +L        Y  +K AV   +  + R 
Sbjct: 122 KAIFNCTKAVSEIM---KNKKYGVILNTSSVVSLYGQKTGVGYPTSKFAVNGLTKSLAR- 177

Query: 525 EHFSKTGVRVLTVCFG--ATDTALLTDEKL 608
               + G+RV  V  G  ATD     D+KL
Sbjct: 178 -ELGRDGIRVNAVAPGIIATDMVAALDKKL 206


>UniRef50_A6UZF9 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=16; Pseudomonas|Rep:
           Oxidoreductase, short chain dehydrogenase/reductase
           family - Pseudomonas aeruginosa PA7
          Length = 266

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 55/197 (27%), Positives = 98/197 (49%), Gaps = 7/197 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           +   ITGA++GIG ++   L   G + + ++    +A +S+  EL  ++G +  F   D+
Sbjct: 3   RYALITGASSGIGLALAEALARRG-RALILVARQRDALESIAYELAQRFGVEVLFRTCDL 61

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 371
            +     G+L+ + Q +  ID+++NNA +      ++      ++ IE+N+ AL     +
Sbjct: 62  AEPLQLSGLLHELEQGERQIDLLVNNAGIGSAGPFVDQEWAREQELIELNILALA----R 117

Query: 372 AIEIMGKHSGGKGG-TVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
               +G     +GG  ++NV+SVAA      M  Y+A+K+ VL FS   G  E      V
Sbjct: 118 LCHALGTRMAAQGGGQILNVASVAAFQPGAWMSNYYASKAYVLHFSE--GLREELKARAV 175

Query: 549 RVLTVCFGATDTALLTD 599
           +V  +C G T TA   +
Sbjct: 176 KVSVLCPGPTRTAFFRE 192


>UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protein]
           reductase; n=1; Arthrobacter aurescens TC1|Rep: Putative
           3-oxoacyl-[acyl-carrier protein] reductase -
           Arthrobacter aurescens (strain TC1)
          Length = 261

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 55/194 (28%), Positives = 96/194 (49%), Gaps = 6/194 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K V +TGA +G+G +V +  L EG   I + D++E++    + + NS    +     +DV
Sbjct: 9   KTVMVTGAGSGLGAAVFKRFLLEGANVIGV-DLSEDSMARFR-DRNSVLSGQITLKVADV 66

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 371
            D +    I+N  V+E G +DV++NNA +         S  +++  ++VNV  L  +T  
Sbjct: 67  GDPDAIEAIINESVEELGALDVLVNNAGIAPTGPAATTSNELWRSVMKVNVDGLFYATRA 126

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           A+     H     G ++N +SV+ +   +    Y A+K AV+ F+  +     +++ GVR
Sbjct: 127 AL----PHLIQSQGNIVNTASVSGIGADYNYAAYDASKGAVINFTRSVA--VDYAQRGVR 180

Query: 552 VLTVCFGATDTALL 593
              V  G   T LL
Sbjct: 181 CNAVAPGPVLTPLL 194


>UniRef50_A1BFL6 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=2; Chlorobium/Pelodictyon group|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Chlorobium phaeobacteroides (strain DSM 266)
          Length = 280

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 58/199 (29%), Positives = 99/199 (49%), Gaps = 6/199 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K   +TGAA+GIG ++   L++ G + + + DI + AG        +  G        DV
Sbjct: 8   KNAIVTGAASGIGFALAVGLIERGAR-VWVADI-DSAGVERAA---ASLGAGAHPVTLDV 62

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 371
            D   F  ++  V ++ GGID + NNA +++             + I+VN+  ++  TL 
Sbjct: 63  RDAVAFRDLVAGVARDAGGIDFLFNNAGILHSGEVCEFDEEQCNRIIDVNIRGVVNGTLA 122

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           A  +M +    + G ++N +S+A L  + ++  Y  TK AV+ FS+ + R E   + GVR
Sbjct: 123 AYPLMVRQ---RSGHIVNTASLAGLAPAPLLSTYAMTKHAVVGFSSSL-RFE-AERYGVR 177

Query: 552 VLTVCFGATDTALLTDEKL 608
           V  +C    DT LL +E +
Sbjct: 178 VSAICPAGVDTPLLDEEAI 196


>UniRef50_A0VFC2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Delftia acidovorans SPH-1|Rep: Short-chain
           dehydrogenase/reductase SDR - Delftia acidovorans SPH-1
          Length = 301

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 62/201 (30%), Positives = 94/201 (46%), Gaps = 6/201 (2%)
 Frame = +3

Query: 3   LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN 182
           +K   ++  K V +TGA+ GIGE   R L   G K + I    +   K L  EL      
Sbjct: 42  MKTPFDFSQKTVLVTGASMGIGEVFARELARRGAKVVLIARSRDRLEK-LASELPG---- 96

Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNV 344
             +F   D+        + +AV       D+++NNA           ++ + ++ I++NV
Sbjct: 97  -AEFLVEDLATPGAARRVFDAVSARGLLPDLLVNNAGFGTHGRFDELALDMQRETIDLNV 155

Query: 345 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 524
            AL+  T   +  + +  GG    VIN++S AA      M +Y ATK+ VL FS  +   
Sbjct: 156 GALVELTHLCLPALEQRQGG----VINIASTAAFQPVPYMAVYAATKAFVLSFSEALW-- 209

Query: 525 EHFSKTGVRVLTVCFGATDTA 587
             +   GVRVL +C GATDTA
Sbjct: 210 AEYRPRGVRVLALCPGATDTA 230


>UniRef50_A0LZZ5 Cluster: Short-chain dehydrogenase/reductase family
           protein; n=1; Gramella forsetii KT0803|Rep: Short-chain
           dehydrogenase/reductase family protein - Gramella
           forsetii (strain KT0803)
          Length = 271

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 51/202 (25%), Positives = 104/202 (51%), Gaps = 6/202 (2%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
           ++++K V ITG A+GIG  + +  +++G   + ILDI + A + ++++L +       F 
Sbjct: 3   KFRNKTVLITGGASGIGLLLTKFSIEKGASALIILDIDKPALQQVELQLKTNICQILSF- 61

Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALIT 359
            +D+++E      +  +  +   +D++INNA ++        ++    + ++VN  A + 
Sbjct: 62  ETDLSNEIQIENAVKKITAQNLQVDILINNAGVVTGKNFSEHNLEDIDRNMQVNAIAPMK 121

Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
            T   +  M K    K G ++N+SS A++  +  M +Y A+K A+  +S+ +       +
Sbjct: 122 LTKLLLPEMLKR---KSGHIVNISSAASMLSNPGMSVYCASKWAMTGWSDSLRLEMERER 178

Query: 540 TGVRVLTVCFGATDTALLTDEK 605
           TG++VLTV     DT +    K
Sbjct: 179 TGIKVLTVTPYYIDTGMFEGVK 200


>UniRef50_Q2UEK6 Cluster: Dehydrogenases with different
           specificities; n=2; Aspergillus|Rep: Dehydrogenases with
           different specificities - Aspergillus oryzae
          Length = 261

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 56/203 (27%), Positives = 96/203 (47%), Gaps = 9/203 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  +TGA +GIG      L + G  ++ + +  E  GK    +++++ G++  F  +DV
Sbjct: 13  KVAIVTGAGSGIGRETALCLANAGA-NVVVAEANETTGKETAAKVSAQTGSRGLFILTDV 71

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 368
           +  E    ++ A ++  G +D+ +NNAAL  D+  I       ++K I VN+   +   L
Sbjct: 72  SRSESVQAMVIATIEAFGRLDIAVNNAALHPDASPIAELHEDHWQKIIGVNLVG-VAFCL 130

Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
           K  E+      G GG++IN+SS         M  Y A K  +   +          + G+
Sbjct: 131 K-WELQQMIQQGGGGSIINISSATINRPQEKMSAYIAAKHGITGLTQTAAVEN--GRHGI 187

Query: 549 RVLTVCFG--ATDTALLTDEKLG 611
           RV  +  G  ATD  + T ++LG
Sbjct: 188 RVNALAPGGVATDLTMATMQELG 210


>UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase, chloroplast precursor; n=80; cellular
           organisms|Rep: 3-oxoacyl-[acyl-carrier-protein]
           reductase, chloroplast precursor - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 319

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 60/198 (30%), Positives = 97/198 (48%), Gaps = 8/198 (4%)
 Frame = +3

Query: 33  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELN-SKYGNKTKFYRSDV 209
           VV ITGA+ GIG+++   L   G K   +++ A  A ++ +V     +YG +   +  DV
Sbjct: 78  VVVITGASRGIGKAIALALGKAGCK--VLVNYARSAKEAEEVAKQIEEYGGQAITFGGDV 135

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 371
           +       ++   + + G IDVV+NNA +  D++ I      + + I +N+T +   T  
Sbjct: 136 SKATDVDAMMKTALDKWGTIDVVVNNAGITRDTLLIRMKQSQWDEVIALNLTGVFLCTQA 195

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           A++IM K    K G +IN+SSV  L  +     Y A K  V+ FS    R        V 
Sbjct: 196 AVKIMMKK---KRGRIINISSVVGLIGNIGQANYAAAKGGVISFSKTAAREGASRNINVN 252

Query: 552 VLTVCFGATD-TALLTDE 602
           V+   F A+D TA L ++
Sbjct: 253 VVCPGFIASDMTAELGED 270


>UniRef50_P66778 Cluster: Probable oxidoreductase ephD; n=16;
           Mycobacterium|Rep: Probable oxidoreductase ephD -
           Mycobacterium bovis
          Length = 592

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 57/195 (29%), Positives = 91/195 (46%), Gaps = 6/195 (3%)
 Frame = +3

Query: 27  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
           D +V +TGA +GIG         EG + I I DI E   K    E+ ++ G     Y  D
Sbjct: 324 DTLVSVTGAGSGIGRETALAFAREGAE-IVISDIDEATVKDTAAEIAAR-GGIAYPYVLD 381

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTL 368
           V+D E        V  E G  D+V+NNA +      ++     + + + VN+  ++    
Sbjct: 382 VSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNGCR 441

Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
              + + +   G GG ++NVSS+AA      +  Y  +K+A   FS+C+ R E     GV
Sbjct: 442 AFGQRLVER--GTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCL-RAE-LDAAGV 497

Query: 549 RVLTVCFGATDTALL 593
            + T+C G  DT ++
Sbjct: 498 GLTTICPGVIDTNIV 512


>UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein)
           reductase, putative; n=26; Gammaproteobacteria|Rep:
           3-oxoacyl-(Acyl carrier protein) reductase, putative -
           Idiomarina loihiensis
          Length = 254

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 62/217 (28%), Positives = 97/217 (44%), Gaps = 15/217 (6%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           KD V+ ITG A G+G ++      +G K +A++DI  +     Q +       K   Y  
Sbjct: 4   KDSVIVITGGAQGLGLAMAEDFARQGAK-LALIDINGDVLGEAQEQCEKLGAAKVVGYEV 62

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI---------------YKKAIEV 338
           D+TDEE    +   + QE  GIDV++NNA L+ D + I               ++  ++V
Sbjct: 63  DITDEESVETVFEQIQQEFDGIDVLVNNAGLLRDGLLIKFKDGELKQKMPLQQFQSVLDV 122

Query: 339 NVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 518
           N+T       +A   M K   GK G +IN+SSVA    +     Y ATK+ V+  +    
Sbjct: 123 NLTGTFLCGREAAAQMVK--AGKKGVIINISSVAR-AGNMGQTNYSATKAGVVAMTVTWA 179

Query: 519 RPEHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYL 629
           R     + G+R   +  G  +T +    K    D+ L
Sbjct: 180 R--ELGRYGIRCGAIAPGFIETPMTAQMKPEAVDRAL 214


>UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1;
           Terrabacter sp. DBF63|Rep: Short-chain
           dehydrogenase/redutase - Terrabacter sp. DBF63
          Length = 252

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 57/202 (28%), Positives = 94/202 (46%), Gaps = 7/202 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           MS+    KV  +TG   GIG    ++L+D G + + + D++E+AG      ++   G+  
Sbjct: 1   MSNSLDGKVALVTGGGGGIGRETAKVLVDHGAR-VVVADLSEDAGNGTLEYIDG--GDAV 57

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVT 347
            F R+DVTD      ++ A V   G +D+  NNA        L + ++  + K I VN+T
Sbjct: 58  AFVRADVTDLASMQHLVQAAVDRYGRLDIAHNNAGIEVTGPDLADVTVEQFDKVIAVNLT 117

Query: 348 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527
            +  S +KA EI    + G GG++IN +S            Y  +K  V+  +       
Sbjct: 118 GVFIS-MKA-EIPQMLAQG-GGSIINTASSLGQAALAHQSAYVTSKHGVIGLTRAAA--V 172

Query: 528 HFSKTGVRVLTVCFGATDTALL 593
            +S  G+RV  V  G   T ++
Sbjct: 173 EYSDKGIRVNAVLPGVIQTPMI 194


>UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC
           16129)
          Length = 256

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 58/200 (29%), Positives = 94/200 (47%), Gaps = 10/200 (5%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           +D+V  ITGAA+G G +  ++   EG K +A  DI +E G    VE   + G +    + 
Sbjct: 4   EDRVAVITGAASGQGRAAAKLFASEGAKVVAA-DI-DEGGAQRTVEEIKEAGGEATAVKV 61

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNV-----TALITSTL 368
           DV+ E     ++ +     G +DV+ NNA +   + G  K A  V        A++   L
Sbjct: 62  DVSREPDVRAMVESATDRYGRLDVLFNNAGVGYSASGRMKMASVVETPEKDWDAILAINL 121

Query: 369 KAIEIMGKHS----GGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHF 533
           K + +  KH+      +G G++IN +S+ AL        Y A K  V+ FS  +     +
Sbjct: 122 KGVALGCKHAIPVMERQGYGSIINNASINALVGLPGADAYTAAKGGVVAFSRVLA--VEW 179

Query: 534 SKTGVRVLTVCFGATDTALL 593
              G+RV  +C G  DT ++
Sbjct: 180 GPRGIRVNCICPGGVDTPMI 199


>UniRef50_Q0GL61 Cluster: Short-chain dehydrogenase; n=3;
           Lactobacillus reuteri|Rep: Short-chain dehydrogenase -
           Lactobacillus reuteri
          Length = 277

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 66/195 (33%), Positives = 101/195 (51%), Gaps = 8/195 (4%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKY----GNKTK 191
           +++VV ITG ++GIG+     L  E  +  AI+ +     + LQ E+  K     G    
Sbjct: 12  RNEVVLITGGSSGIGKE----LAFEAARRGAIVVVVSRNLEKLQ-EVAKKCLILSGRPAF 66

Query: 192 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 371
            Y+ DVTD +    +L+ V  E GGIDV+IN+A L  D I + K++       + T+ L 
Sbjct: 67  AYQLDVTDPDQIDDVLSKVQHEVGGIDVLINSAGL-GDFIPVVKESYSSMEKMVHTNLLA 125

Query: 372 AIEI---MGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
            + I   + K    +G G +IN+ S+A    +    +Y ATK+ V+QF N + R E  + 
Sbjct: 126 LMYISRCVAKQMMDQGYGAIINMGSLAGKLPTPNSAVYSATKAGVIQFDNVL-RME-VAD 183

Query: 540 TGVRVLTVCFGATDT 584
            GV+VLTV  G  DT
Sbjct: 184 YGVQVLTVNPGPIDT 198


>UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Enterobacter sp. 638|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Enterobacter sp.
           638
          Length = 242

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 59/200 (29%), Positives = 100/200 (50%), Gaps = 6/200 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           M+ E K +V  +TGA++GIGE++ R L   G++ + +    E     + V L S+ G+  
Sbjct: 1   MNIEKKKRVAVVTGASSGIGEALARELAGNGIQVVLLARRFER----IDV-LASELGHGA 55

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 350
              ++DVTD E  +   N V Q  GG+D++INNA +M      +  +  +++ +E N+  
Sbjct: 56  IAIKADVTDRESIVAAANQVEQTLGGVDILINNAGVMLTGPFDSSQLDEHRQMVETNLLG 115

Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
            +T T    E+         G ++N+SSVA         +Y ATK  +  +S  + R E 
Sbjct: 116 AMTVT----EVFLPQLRRNKGDLVNISSVAGRVAPSGFAVYAATKWGINGWSEAL-RVE- 169

Query: 531 FSKTGVRVLTVCFGATDTAL 590
             +  +RV+ +  GA  T L
Sbjct: 170 -LQPDIRVMVIEPGAIATEL 188


>UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x;
           n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase
           FadB2x - Pseudomonas stutzeri (strain A1501)
          Length = 258

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 67/221 (30%), Positives = 101/221 (45%), Gaps = 17/221 (7%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           +DKVV ITG A+G+G +    L  E    IAI D+  EAG+     L ++   +  F  +
Sbjct: 4   QDKVVVITGGASGLGLATAHYLAAEKGARIAIFDLNVEAGEQAVAALGTE---RAMFVAT 60

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-----------SIGIYKKAIEVNVTA 350
           DV+ EE     ++AV+   G I V IN AA+               +  + +A  +N+  
Sbjct: 61  DVSSEESVQNAVDAVMANFGAIHVCINGAAVPTGFKILGKEGKAAPLARFAQATAINLNG 120

Query: 351 LITSTLKAIEIMGKH---SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGR 521
           +     K  E M K+   +G + G VINVSS AA         Y ATK+ V+  +    R
Sbjct: 121 VFNVMSKCAEHMAKNEAEAGEERGVVINVSSGAAYEGQLGQCAYSATKAGVIGLNMPAAR 180

Query: 522 PEHFSKTGVRVLTVC---FGATDTALLTDEKLGTFDKYLES 635
                  GVRV  +    F  T  A L ++ LG+  + +E+
Sbjct: 181 --ELGAIGVRVNAIAPGLFLTTMVAALDEKVLGSLKEQMEA 219


>UniRef50_A5BP77 Cluster: Putative uncharacterized protein; n=1;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 387

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 58/209 (27%), Positives = 103/209 (49%), Gaps = 20/209 (9%)
 Frame = +3

Query: 63  IGESVVRILLDEGVKHIAILDIAEEAGK---SLQVELNSKYGNK-----TKFYRSDVTDE 218
           IG+++   L ++G+  + ++D +EE GK   SL  + N+K+  K       F R DVT+ 
Sbjct: 36  IGKAISLALGEKGI-FVTVVDFSEEGGKEVASLVEKENAKFHPKLGFPSAMFIRCDVTNT 94

Query: 219 EHFLGILNAVVQEQGGIDVVINNAAL---------MNDSIGIYKKAIEVNVTALITSTLK 371
                     +   GG+D+ +N+A +           ++ G++++ I VN+ A+I  T  
Sbjct: 95  RELAAAFKKHLATYGGLDICVNSAGIGTHEPFHKDQTENSGLWRRTINVNLVAVIDCTRL 154

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           AI+ M   +  K G +IN+ S + L   +V PIY A+K  V+ F+  +     + + G+R
Sbjct: 155 AIQTM--QAAKKPGVIINMGSASGLYPMYVDPIYSASKGGVVLFTRSLA---PYKRHGIR 209

Query: 552 VLTVC--FGATDTALLTDEK-LGTFDKYL 629
           V  +C  F  T+     D K +G    Y+
Sbjct: 210 VNVLCPEFVQTEMGSSVDSKFIGLMGGYV 238


>UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 284

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 67/220 (30%), Positives = 100/220 (45%), Gaps = 19/220 (8%)
 Frame = +3

Query: 27  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE--EAGKSLQVELNSKYGNKTKFYR 200
           DKV  ITG++ GIG++  R+L  EG K       AE  E  K++ +      GN      
Sbjct: 6   DKVAIITGSSNGIGQATARLLASEGAKVTVTGRNAERLEETKNILLGAGVPEGN-VLVVV 64

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL----------MNDSIGIYKKAIEVNVTA 350
            D+T E     ++ + + + G ID+++NNA            +N SI  Y K  E+NV +
Sbjct: 65  GDITQESVQENLIKSTLDKFGKIDILVNNAGAGIPDAQGKSGVNQSIDTYHKTFELNVQS 124

Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHV-MPIYFATKSAVLQFSNCIGRPE 527
           +I  T KA      H     G ++N+SS+ A   + V  P Y   K+A+ Q++       
Sbjct: 125 VIEMTQKA----RPHLAKTQGEIVNISSIGAGPAAQVASPYYSIAKAALDQYTRTAA--I 178

Query: 528 HFSKTGVRVLTVCFGATDTAL------LTDEKLGTFDKYL 629
                G+RV +V  GA  T        LT+EK   F  YL
Sbjct: 179 DLVPEGIRVNSVSPGAVSTGFSAVSRGLTEEKSKAFYDYL 218


>UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Burkholderiaceae|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia sp. (strain
           383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
           / R18194))
          Length = 252

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 51/182 (28%), Positives = 91/182 (50%), Gaps = 6/182 (3%)
 Frame = +3

Query: 27  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
           +KV  +TGAA+G+G +   +L  EG + + + DI E+AG++L  E+    G+   F R D
Sbjct: 6   NKVALVTGAASGVGRADALLLAAEGAR-VVLTDIDEDAGRALAREI----GDAALFVRHD 60

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 368
           + DE  +   + + +   G +DV++NNAA+       + S+  +++ +  N         
Sbjct: 61  IADEAGWQHAIASTLDRFGRLDVLVNNAAICPVGSIEDTSLDTWRRVMRTNADGYFLGCK 120

Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
            AI  M        G+++ +SSVAAL    +M  Y  +K AV   +  +    H  ++G 
Sbjct: 121 YAIGAM--KGNDTPGSIVMMSSVAALGGLPMMCAYTGSKGAVTALARSVA--VHCKRSGY 176

Query: 549 RV 554
           R+
Sbjct: 177 RI 178


>UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Acidobacteria bacterium (strain Ellin345)
          Length = 271

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 56/199 (28%), Positives = 92/199 (46%), Gaps = 4/199 (2%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           M  +   KV  +TG A GIGE+  R +   G   +AILD  E+AG      + + +G + 
Sbjct: 1   MKIDLSGKVAVVTGGAMGIGEACARKIALAGAS-VAILDPNEDAGTKTAAAIRA-HGGEC 58

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTL 368
           KF+R DV+  +     +  V+ +   ID++++NA +     G      E +   +I   L
Sbjct: 59  KFFRCDVSKSKDVEQAVGDVITKHSQIDILVSNAGI--QYYGDVITTPEDDWDRVIGVNL 116

Query: 369 KAIEIMGK----HSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
           K   ++ K    H    GG ++ + SV + T       Y  +K AVL  +  +     ++
Sbjct: 117 KGCFLISKFCVPHMISNGGAIVVLGSVQSFTAIQNSAAYVTSKHAVLGLARAMAL--DYA 174

Query: 537 KTGVRVLTVCFGATDTALL 593
             G+RV  VC G  DT +L
Sbjct: 175 HKGIRVNCVCPGTIDTPML 193


>UniRef50_A6CTS3 Cluster: Putative uncharacterized protein; n=1;
           Bacillus sp. SG-1|Rep: Putative uncharacterized protein
           - Bacillus sp. SG-1
          Length = 260

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 61/202 (30%), Positives = 95/202 (47%), Gaps = 7/202 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           K+KVV ITGA++G+G    +         + +   +E+   +L  EL  K+G K      
Sbjct: 2   KNKVVVITGASSGLGVEFAKQFAGRSYD-LVLTARSEDKLNNLAKELEGKHGIKAHVIPI 60

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL----MNDSIGIYKKA--IEVNVTALITST 365
           D++       +   VV      +++INNA        +   I K+   IEVN+TAL   T
Sbjct: 61  DLSQHGSAKTLHEKVVSLGLTTEILINNAGFGLFGEFEDTDIQKEVDMIEVNITALTELT 120

Query: 366 LKAIEIMGKHSG-GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
               +  GK    G  G ++NV+SVAA     +M +Y+ATK+ VL  S  +     +   
Sbjct: 121 ----KYFGKEMVVGNTGKILNVASVAAFQPGPLMAVYYATKAYVLSLSEALS--NEWKDK 174

Query: 543 GVRVLTVCFGATDTALLTDEKL 608
           GV+V  +C GAT+T      +L
Sbjct: 175 GVKVSVLCPGATETGFSNSAEL 196


>UniRef50_A4XF64 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Novosphingobium aromaticivorans (strain DSM 12444)
          Length = 266

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 56/191 (29%), Positives = 90/191 (47%), Gaps = 4/191 (2%)
 Frame = +3

Query: 27  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
           ++   +TGAA GIGE + R    EG   + + D  +E G ++  +L    G + +F R D
Sbjct: 8   NRAAVVTGAADGIGEGIARRFAAEGAA-VVVADYDDERGPAVARDLRG-LGARAEFIRCD 65

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTAL---ITSTLKAI 377
           V+  E  +G ++  V+  G +D+++NNA      + I KK  E    AL   + +T  A+
Sbjct: 66  VSRREDVIGAVDLCVERFGSVDILVNNAYRGEGPVRIEKKTDERFDEALRMCLFATKWAM 125

Query: 378 EIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
           E    H   KG G VIN++S+  +        Y   K AV  +S    R   ++  G+ V
Sbjct: 126 ERALPHMKAKGWGRVINMASLNGVNAHMGSADYNVAKEAVRAYSRTAAR--EWAPYGICV 183

Query: 555 LTVCFGATDTA 587
             +C  A   A
Sbjct: 184 NVICPAAVSAA 194


>UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1;
           Flavobacteriales bacterium HTCC2170|Rep: Probable
           glucose 1-dehydrogenase - Flavobacteriales bacterium
           HTCC2170
          Length = 268

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 53/198 (26%), Positives = 93/198 (46%), Gaps = 5/198 (2%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           K K V +TG + GIG  + R L   G +     +  E++ + L  E+++ YG +T    +
Sbjct: 7   KGKRVLVTGGSRGIGAEICRKLAACGAEVFINYNSNEQSAQDLANEISNSYGVRTGIACA 66

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 383
           DV+  E    +   +    GGID+++NNA    +SI      +E     +I   LK   +
Sbjct: 67  DVSKAEQVKQMFLKMDGVMGGIDILVNNAG--TESIHHVLDLVEEEWDRVINVNLKGPFL 124

Query: 384 MGKHSGGK-----GGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
             K +G +     GG +IN+SS+  +     +  Y + K+ +   S C+      ++  +
Sbjct: 125 CSKEAGDRMEKNGGGVIINISSIHDVVPRKGLIHYCSAKAGLKMLSKCLSL--ELAENNI 182

Query: 549 RVLTVCFGATDTALLTDE 602
           RV++V  GA  T +  DE
Sbjct: 183 RVVSVAPGAISTEMNRDE 200


>UniRef50_Q2U0U8 Cluster: Dehydrogenases with different
           specificities; n=2; Pezizomycotina|Rep: Dehydrogenases
           with different specificities - Aspergillus oryzae
          Length = 271

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 58/215 (26%), Positives = 101/215 (46%), Gaps = 23/215 (10%)
 Frame = +3

Query: 33  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN------KTKF 194
           +  ITGAA+GIG +       +G   IA+LD+ + A +++Q E+NS+         + + 
Sbjct: 6   IALITGAASGIGRACAHTFARDGASGIALLDLDKTALETVQAEINSQSSQDKTARCRVEI 65

Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGI-------YKKAIEVNVTA 350
           Y  +VTDE     ++N+  Q    +D V+N A + M    G        +++ ++VN+T 
Sbjct: 66  YPVNVTDENRVDEVINSAAQTFSRLDYVVNAAGIAMKHQGGAAFAETSDWQRILDVNLTG 125

Query: 351 LITSTLKAIEIMGKHS------GGK---GGTVINVSSVAALTQSHVMPIYFATKSAVLQF 503
                  A  IM           G+    G+++N SS+  +    +   Y ATK AV+  
Sbjct: 126 TFFVLRAAARIMLSQEPIRSSIDGRPLQRGSIVNFSSIQGVAGIPLSTAYTATKHAVIGL 185

Query: 504 SNCIGRPEHFSKTGVRVLTVCFGATDTALLTDEKL 608
           +      E ++K G+R+  +C G T+T + T   L
Sbjct: 186 TRTAS--EDYAKDGLRINAICPGYTETPMTTKSPL 218


>UniRef50_Q5UYC2 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=2; Halobacteriaceae|Rep:
           3-oxoacyl-[acyl-carrier protein] reductase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 254

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 56/211 (26%), Positives = 98/211 (46%), Gaps = 9/211 (4%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE---EAGKSLQVELNSKYGNKTKF 194
           +DKV  +TG A+G G ++ R   + G   + + D  +   E GK     + ++      F
Sbjct: 6   EDKVAVVTGGASGFGRAICRRYAEHGA-DVIVADRQQDPREGGKPTHELVEAETDRTAHF 64

Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALI 356
              DVTD +  L +  A  +E GGID+++NNA +         +   Y + ++VN   + 
Sbjct: 65  VECDVTDPDD-LEVAVAAAEELGGIDIMVNNAGISEIADFYETTEEDYDRLMDVNTKGVF 123

Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
                A E M ++    GGTVIN+SS   +  + ++  Y  +K AV  F+  +   +  S
Sbjct: 124 FGAQVATEAMRENG---GGTVINMSSSGGIRGTGLLVNYCTSKGAVRLFTYALA--DRLS 178

Query: 537 KTGVRVLTVCFGATDTALLTDEKLGTFDKYL 629
              +RV  +  G + T +  DE++    K +
Sbjct: 179 NYNIRVNAIHPGYSKTQMFEDERIDDTTKMM 209


>UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=225; cellular organisms|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Vibrio
           cholerae
          Length = 244

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 59/201 (29%), Positives = 97/201 (48%), Gaps = 9/201 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  +TGA+ GIG+++  +L + G K I       E+G      ++   G+  K    +V
Sbjct: 6   KVALVTGASRGIGKAIAELLAERGAKVIGTA--TSESGAQA---ISDYLGDNGKGMALNV 60

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK------AIEVNVTALITSTLK 371
           T+ E    +L A+  E GG+D+++NNA +  D++ +  K       +E N+T++   +  
Sbjct: 61  TNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLSKA 120

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
            +  M K    + G +INV SV     +     Y A K+ V+ F+  + R    +  GV 
Sbjct: 121 VLRGMMKK---RQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAR--EVASRGVT 175

Query: 552 VLTVC--FGATD-TALLTDEK 605
           V TV   F  TD T  L DE+
Sbjct: 176 VNTVAPGFIETDMTKALNDEQ 196


>UniRef50_Q7M9W0 Cluster: 3-OXOACYL-REDUCTASE; n=24;
           Epsilonproteobacteria|Rep: 3-OXOACYL-REDUCTASE -
           Wolinella succinogenes
          Length = 247

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 44/166 (26%), Positives = 82/166 (49%), Gaps = 6/166 (3%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
           ++  K V ITG++ GIG  + R+L + G+K              L+ E+ +K G +    
Sbjct: 2   KFSGKNVLITGSSRGIGADIARVLAEMGLKVWINYRSQSSLADELKAEIEAK-GGQAAVI 60

Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALIT 359
             D TDEE F+  +  ++   G +  ++NNA + ND + I      ++  IE N+T+   
Sbjct: 61  SFDATDEEAFISGIKTIIDADGELAYLVNNAGITNDKLAIRMKTEEFRSVIEANLTSAFI 120

Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVL 497
            + +A++ M K    + G+V+N+SS+     +     Y A+K  ++
Sbjct: 121 GSREALKSMSKQ---RFGSVVNISSIVGERGNAGQTNYSASKGGMI 163


>UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chain
           dehydrogenase/reductase family; n=1; Photobacterium
           profundum|Rep: Hypothetical oxidoreductase, short-chain
           dehydrogenase/reductase family - Photobacterium
           profundum (Photobacterium sp. (strain SS9))
          Length = 255

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 54/194 (27%), Positives = 89/194 (45%), Gaps = 7/194 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  I+G  +GIGE+  R+   +G   + ++   E  G+ L  ELN++Y   T F ++D+
Sbjct: 10  KVALISGITSGIGEATARLFSQQGAS-LVLVARNENKGQMLAEELNAQY--PTLFIKADI 66

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 368
           T       +    + E GGID   NNA        +   S  I+ + I  N+        
Sbjct: 67  TQANQVDQVFEQTMAEFGGIDCAFNNAGIDGSKQPISETSDEIWNQIINTNLNGTWNMLN 126

Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
           + + IM K      GT++N++S+ ++        Y  ++ AVL  +        ++K GV
Sbjct: 127 RQLSIMSKQG---HGTIVNMASICSVLARPNRAAYNTSRHAVLGLTR--SAAVEYAKQGV 181

Query: 549 RVLTVCFGATDTAL 590
           RV  V  GA DT +
Sbjct: 182 RVNAVAPGAIDTPI 195


>UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacillus
           thuringiensis
          Length = 247

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 50/196 (25%), Positives = 98/196 (50%), Gaps = 6/196 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  +TG A GIG+++   L  EG K +   + ++EA ++L  EL  K G+     ++DV
Sbjct: 7   KVAIVTGGAKGIGKAITVALAQEGAKVVINYNSSKEAAENLVNEL-GKEGHDVYAVQADV 65

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 371
           +  E    ++   V   G +D+++NNA +  D      +   +++ I+VN++++  +T  
Sbjct: 66  SKVEDANRLVEEAVNHFGKVDILVNNAGITRDRTFKKLNREDWERVIDVNLSSVFNTTSA 125

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
            +  +   +  + G +I++SS+           Y A K+ +L F+  +      +KT V 
Sbjct: 126 VLPYI---TEAEEGRIISISSIIGQAGGFGQTNYSAAKAGMLGFTKSLAL--ELAKTNVT 180

Query: 552 VLTVCFGATDTALLTD 599
           V  +C G  DT ++ +
Sbjct: 181 VNAICPGFIDTEMVAE 196


>UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein)
           reductase; n=1; Bacillus sp. SG-1|Rep:
           3-oxoacyl-(Acyl-carrier-protein) reductase - Bacillus
           sp. SG-1
          Length = 246

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 54/195 (27%), Positives = 96/195 (49%), Gaps = 6/195 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           K+K   ITG+A GIG +  +    EG K + + D  E  G + + E   + G  T FY+ 
Sbjct: 4   KNKTAVITGSANGIGLAAAKKFAQEGCK-VIMADYDENKGAA-EAEKLQEEGGDTVFYQV 61

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITST 365
           DV + E    +   V+++ G ID++INNA +  D++        +++ ++VN+T +   T
Sbjct: 62  DVANRESVDNLAAWVLRDYGSIDILINNAGITRDALMAKMREDDFQRVLDVNLTGVFHCT 121

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
              +  +   + GK G +IN +S + L  +     Y A+K+AV+  +    +   F   G
Sbjct: 122 QALLPAL--INSGK-GKIINTASASGLYGNVGQTNYAASKAAVIGMTKTWAK--EFGPKG 176

Query: 546 VRVLTVCFGATDTAL 590
           + V  V  G  +T +
Sbjct: 177 INVNAVAPGVIETEM 191


>UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like
           protein; n=1; Reinekea sp. MED297|Rep: Short-chain
           alcohol dehydrogenase-like protein - Reinekea sp. MED297
          Length = 672

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 51/169 (30%), Positives = 90/169 (53%), Gaps = 8/169 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KVV ITG ++GIG++    L   G   I     AE+  ++  +++ S  G     +++D+
Sbjct: 385 KVVLITGGSSGIGKATAMRLSKAGATVIICARDAEKLRRA-HLDIESTGGTVVS-HQADI 442

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNA------ALMN--DSIGIYKKAIEVNVTALITST 365
           T  +    +   + +E  G+D++INNA      ++M   D +  +++ IE+N  A +  T
Sbjct: 443 TQPDDVDRLFGMIEREFAGLDILINNAGHSIRRSVMQSLDRLHDFQRTIELNYLASVAIT 502

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNC 512
           LKA+ +M +    + G VIN+SS+  L+ S     Y A+K+A+  FS C
Sbjct: 503 LKALPMMDRR---REGHVINISSIGVLSNSPRFSAYVASKAALEAFSRC 548


>UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Marinomonas sp. MED121|Rep: Short-chain
           dehydrogenase/reductase SDR - Marinomonas sp. MED121
          Length = 255

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 58/207 (28%), Positives = 101/207 (48%), Gaps = 7/207 (3%)
 Frame = +3

Query: 21  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
           +KD+VV ITGA+ G+G+   +    +G K +A+ D+   A   L  EL  + G +     
Sbjct: 4   FKDQVVLITGASGGLGKEAAKQFAQQGAK-LALCDLNVAALNDLGTEL-IEQGYEVFSQP 61

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNA-------ALMNDSIGIYKKAIEVNVTALIT 359
            DV++E+     ++      G +DV INNA        L +     +++ +++NV  +  
Sbjct: 62  CDVSNEQEVQSFIDNTAAHFGRLDVAINNAGIDPKHSTLADMDTRDFERVMDINVKGVYL 121

Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
                I  M K     GG + N+SSVA ++ +  M  Y A+K AV+  +  +     + +
Sbjct: 122 CMKYQIPHMIKQG---GGAICNMSSVAGISGAPFMSAYAASKHAVIGLTKSVA--HEYGR 176

Query: 540 TGVRVLTVCFGATDTALLTDEKLGTFD 620
            G+RV +VC   T T ++ ++ L T D
Sbjct: 177 AGIRVNSVCPYITMTDMV-EQHLKTLD 202


>UniRef50_A2U319 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Polaribacter dokdonensis MED152|Rep: Short-chain
           dehydrogenase/reductase SDR - Polaribacter dokdonensis
           MED152
          Length = 259

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 60/193 (31%), Positives = 96/193 (49%), Gaps = 8/193 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K   ITGA++G+G+   +I    G   + I+  +++  + L+ +L  K+G        D+
Sbjct: 3   KTALITGASSGLGKEFAKIHAKNG-GDLVIVARSKDKLQKLKEKLEKKHGVHVSIIEKDL 61

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG-IYKKA-------IEVNVTALITST 365
           T+      + N V   +  ID +INNA      IG  +++A       I++N+ AL   T
Sbjct: 62  TEPNAAQEVYNFVKFSKIEIDYLINNAGF--GGIGKFHERAWAQDLAMIQLNIIALTDLT 119

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
            K +    + + GK   ++NVSS A+L    +  +YFATK+ V  FSN I    H +K  
Sbjct: 120 RKFLPDFVERNQGK---ILNVSSTASLMAGPMQAVYFATKAFVTSFSNAIAEELHDTK-- 174

Query: 546 VRVLTVCFGATDT 584
           V V T+  GAT T
Sbjct: 175 VTVTTLMPGATKT 187


>UniRef50_UPI00015B4F48 Cluster: PREDICTED: similar to
           ENSANGP00000025535; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ENSANGP00000025535 - Nasonia
           vitripennis
          Length = 254

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 58/201 (28%), Positives = 100/201 (49%), Gaps = 8/201 (3%)
 Frame = +3

Query: 21  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
           W  KV  +TGA+ GIG ++V  LLD G   + ++ +A    K  ++ ++ +   K     
Sbjct: 4   WAGKVAVVTGASVGIGAAIVNKLLDNG---LIVVGLARRVEKVKEL-IDDRPEAKLHAVE 59

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITS 362
            DVT+EE+ +     + +  G +DV++NNA       L + S+  ++  ++VNV  L   
Sbjct: 60  CDVTNEENVVTAFAWIKENLGSVDVLVNNAGVTKETTLSDGSLADWRNVLDVNVLGLCVC 119

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHV--MPIYFATKSAVLQFSNCIGRPEHFS 536
           T +A+  M +  G     +I++SS+A      V    +Y ATK AV   +  + R E  +
Sbjct: 120 TREAVRSMRECDG--ESVIIHISSLAGERVPAVPGFNVYPATKRAVNALAQTL-RHE-LA 175

Query: 537 KTGVRVLTVCFGATDTALLTD 599
            T +RV T+  G   T L+ +
Sbjct: 176 GTKIRVTTISPGLVATELMAN 196


>UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium
           japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum
          Length = 248

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 57/193 (29%), Positives = 93/193 (48%), Gaps = 5/193 (2%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  ITGA +GIG ++ R+   EG K + + D+A E G +L   L +  G+   F   DV
Sbjct: 7   KVAVITGAGSGIGAAIARLFAVEGAK-VLLGDLA-EGGAALAAGLAAD-GHAAGFQHVDV 63

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 389
           TDE     ++ A V   G +D+++ NA +      I++  + V+   +I   L  + I  
Sbjct: 64  TDEASVAELMQAAVTLFGRLDILVANAGIPERKSPIHELDL-VDWRRVIDVDLTGVAICN 122

Query: 390 KHSGG-----KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
           K + G      GG ++N++S+ A         Y A K+AV+  +  +     ++  G+R 
Sbjct: 123 KFAAGIMRATGGGAIVNMASILAHVGQENSNAYSAAKAAVVNLTRSVALT--YALQGIRA 180

Query: 555 LTVCFGATDTALL 593
             V  G  DT LL
Sbjct: 181 NCVSPGYVDTPLL 193


>UniRef50_Q3IVD0 Cluster: Short-chain alcohol dehydrogenases; n=2;
           Rhodobacteraceae|Rep: Short-chain alcohol dehydrogenases
           - Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 /
           NCIB 8253 / DSM158)
          Length = 247

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 60/201 (29%), Positives = 98/201 (48%), Gaps = 6/201 (2%)
 Frame = +3

Query: 36  VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 215
           + ITGA +GIG    R    EG   +A++D  E A    QV  +   G+    +  DVTD
Sbjct: 10  IVITGAGSGIGRESARQFAREGAT-LALIDRDEAAA---QVTADETGGH---VFALDVTD 62

Query: 216 EEHFLGILNAVVQEQGGIDVVINNAALMN----DSIGI--YKKAIEVNVTALITSTLKAI 377
           E     ++    +  GGID ++N+A ++     D IG+  +++ ++VN+T        A+
Sbjct: 63  EAAVETVVGRAAEALGGIDGLLNSAGILTMKTVDDIGVEEFRRVVDVNLTGTFLVCQAAL 122

Query: 378 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
             + K        ++N++S  AL  S     Y A+K+AV+ FS  I +        VRV 
Sbjct: 123 PWLRKE---PKAAIVNIASAQALLPSLTGSAYAASKAAVMMFSKSIAKE---LAPAVRVN 176

Query: 558 TVCFGATDTALLTDEKLGTFD 620
            +C GAT+T  +TD+ +   D
Sbjct: 177 IICPGATETP-MTDQGVAPDD 196


>UniRef50_Q3VZL7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Frankia sp. EAN1pec|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 261

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 62/200 (31%), Positives = 92/200 (46%), Gaps = 11/200 (5%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
           E   KV  ITG   G G++    L + G  H+ + DI  +   +   EL +  G+ T   
Sbjct: 14  EHAGKVALITGGGRGFGKAFGAALTERGA-HVVLADIDGDVASAAAAELTALGGSATGV- 71

Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI---------GIYKKAIEVNVTA 350
             DVTDE     ++  +V+  GG+D+++NNA L + +          G  ++  EVNV  
Sbjct: 72  TCDVTDEARVGEVVADIVRAHGGLDILVNNAGLHSAAFNKPTAELGAGQIRRLFEVNVMG 131

Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
           ++  TL A + M   SG  G  V+N+SS AA         Y  +K AV  F+    R   
Sbjct: 132 VVICTLAAKDAM---SGRAGAAVVNISSSAAYAN---RTAYGVSKLAVRGFTAQFAR--E 183

Query: 531 FSKTGVRVLTVCFG--ATDT 584
            +  GVRV  +  G   TDT
Sbjct: 184 LAAVGVRVNAIAPGLILTDT 203


>UniRef50_Q03X86 Cluster: Putative uncharacterized protein; n=1;
           Leuconostoc mesenteroides subsp. mesenteroides ATCC
           8293|Rep: Putative uncharacterized protein - Leuconostoc
           mesenteroides subsp. mesenteroides (strain ATCC 8293
           /NCDO 523)
          Length = 247

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 63/201 (31%), Positives = 98/201 (48%), Gaps = 9/201 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV+ ITGA++GIGE++ +     G K I +    EE  K ++ ++ +  G + ++  +DV
Sbjct: 5   KVIVITGASSGIGEAIAKKQAAAGDK-IVLGARREENLKQIKADIEAG-GGQAEYLVTDV 62

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 371
           TD E    +    +   G IDV INNA LM  S+ I      + + I+VN+   +     
Sbjct: 63  TDVEQVKALAQKAMDAYGRIDVWINNAGLMPHSLLIDARIDDWNRMIDVNLKGTLYGIAA 122

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           A  I    + G     IN+ SVA+L       +Y ATK AV   S  +   E  +   VR
Sbjct: 123 AQHIFHDQNTGH---FINLGSVASLYSHAGGAVYSATKWAVKAISESLREEEAQAGKNVR 179

Query: 552 VLTVCFGATDTAL---LTDEK 605
           V ++  GA ++ L   +TD K
Sbjct: 180 VTSLYPGAIESELVANMTDSK 200


>UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5;
           Proteobacteria|Rep: Short chain dehydrogenase -
           Janthinobacterium sp. (strain Marseille) (Minibacterium
           massiliensis)
          Length = 278

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 62/201 (30%), Positives = 89/201 (44%), Gaps = 7/201 (3%)
 Frame = +3

Query: 12  SHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK 191
           S+E     V ITGA TGIG +       EG + +A+    EEAG +L  EL +  GN+ +
Sbjct: 27  SNEMNTPTVLITGALTGIGRATAFAFAREGYR-VAVSGRREEAGNALAAELRA-LGNEAE 84

Query: 192 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTA 350
           F  +DV  E     ++   V   G IDV +NNA        ++  S   Y +   VNV  
Sbjct: 85  FLLADVRFEADVRNLVEQTVVRFGRIDVAVNNAGTEGQLAPIVEQSAANYAETFGVNVLG 144

Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
            + S    + +M        G++IN+SSVA         +Y A+K AV   +        
Sbjct: 145 TMLSLKHEMRVMLAQG---SGSIINLSSVAGKVGIAGASVYVASKHAVEGLTKSAAL--E 199

Query: 531 FSKTGVRVLTVCFGATDTALL 593
            +  GVRV  V  G   T +L
Sbjct: 200 GAAAGVRVNAVAPGPVATEML 220


>UniRef50_Q8FA17 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=3; Leptospira|Rep: 3-oxoacyl-[acyl-carrier
           protein] reductase - Leptospira interrogans
          Length = 247

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 50/189 (26%), Positives = 88/189 (46%), Gaps = 2/189 (1%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           K+K V +TG+  GIG         EG K+     I    G S Q  +    G+  K + +
Sbjct: 8   KNKTVLVTGSTRGIGRYFA-----EGFKNAGA--IVYGTGSS-QESIKKFDGSGIKGFAA 59

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAI 377
           D+   +    I+ ++V+E G +DV++NNA + ++    + K  E+   +    T   +A 
Sbjct: 60  DIRQPDVMTPIIESIVKEHGRLDVLVNNAGIASNKPAAFLKEDEIESIIQTNFTGVFRAC 119

Query: 378 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
               K    KGG +IN++S+  +  + +  +Y  TK AV+  +  +     +  +G RV 
Sbjct: 120 TAYYKIHKKKGGNIINIASILGMRGTKLASVYSGTKGAVINMTRALA--VEWIGSGYRVN 177

Query: 558 TVCFGATDT 584
            +C G  DT
Sbjct: 178 AICPGFIDT 186


>UniRef50_Q0VL04 Cluster: Oxidoreductase, putative; n=1; Alcanivorax
           borkumensis SK2|Rep: Oxidoreductase, putative -
           Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM
           11573)
          Length = 581

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 55/194 (28%), Positives = 97/194 (50%), Gaps = 7/194 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K V ITGA +GIG          G   +   DI  E   +    + ++ G +    + DV
Sbjct: 315 KRVIITGAGSGIGRETALAFARRGAL-VVCTDINSEEAAATARTITAE-GGEALSRKCDV 372

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALIT-STL 368
           ++      +   V +E G  D+V+NNA      +L++ S+  +++ + VN+  +I  S L
Sbjct: 373 SNTRSMEALATWVEKELGAPDIVVNNAGIGLSGSLLDTSVKDWQQVLGVNLWGVIHGSRL 432

Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
            A +++ +   G+ G ++N++S AA   S ++P Y  +KSAVL FS C+ R E   +  +
Sbjct: 433 FARQMIDQ---GRAGHIVNIASAAAFMPSRMLPAYATSKSAVLMFSECL-RAE-MDEHNI 487

Query: 549 RVLTVCFGATDTAL 590
            V  +C G  +T +
Sbjct: 488 GVSAICPGIINTPI 501


>UniRef50_Q0S5L2 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=3; Bacteria|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus
           sp. (strain RHA1)
          Length = 258

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 52/184 (28%), Positives = 87/184 (47%), Gaps = 6/184 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K + +TG A GIG ++V+    EG   +   D+ EE G+ +  E +       +F R D+
Sbjct: 6   KRILVTGGAQGIGAAIVKAYAMEGAT-VRSYDLNEEGGRVVAEEASDAGPGVVEFSRLDI 64

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG------IYKKAIEVNVTALITSTLK 371
           TD +    +  +  +E GGIDV++N A L   ++       +++    VNV   I +   
Sbjct: 65  TDGDATESLFRSAARELGGIDVLVNIAGLQRSAMAEEITDDLFESIYRVNVLGTIHTNQS 124

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           A  IM   S G  G +IN  S++  T       Y ++K AV  ++  + R   +  +G+R
Sbjct: 125 AYRIM--QSAGT-GAIINFGSMSGFTGELANATYGSSKGAVHTWTRTVAR--EWGPSGIR 179

Query: 552 VLTV 563
           V  V
Sbjct: 180 VNAV 183


>UniRef50_A7IMM1 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=1; Xanthobacter autotrophicus Py2|Rep:
           Short-chain dehydrogenase/reductase SDR precursor -
           Xanthobacter sp. (strain Py2)
          Length = 261

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 57/201 (28%), Positives = 97/201 (48%), Gaps = 8/201 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           KDK + ITGAA GIG ++ + L  +G + I + D++E A +++  E+ +  G        
Sbjct: 5   KDKSIVITGAAGGIGAAIAKALAADGAR-ITVADLSEPAARAVAGEITAA-GGTAIAVAV 62

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 365
           DV        +L+  V   G +DV+ NNA +      ++ +   ++   +VN   ++   
Sbjct: 63  DVRQRAQVRALLDEAVAAHGRLDVLFNNAGVAQTRPFLDITEDDWRFVTDVNALGVLIGM 122

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
            +AI+   K  GG GG ++N +S+AA      +  Y A+K AV+  +    R   F K  
Sbjct: 123 QEAIKTF-KRQGG-GGKIVNTASIAAKQGYEPLAHYCASKFAVVALTQAAARA--FGKDQ 178

Query: 546 VRVLTVCFG--ATDTALLTDE 602
           + V   C G  ATD   + D+
Sbjct: 179 ITVNAFCPGVVATDMWKIIDK 199


>UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=1; Marinomonas
           sp. MED121|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family protein - Marinomonas sp.
           MED121
          Length = 259

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 58/185 (31%), Positives = 90/185 (48%), Gaps = 6/185 (3%)
 Frame = +3

Query: 36  VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 215
           V +TG A+GIGE++V+ L  +G   ++  DI EEAG+ L   LNS +G K  F   D+TD
Sbjct: 20  VLVTGGASGIGEALVKALAQQGCA-VSFFDIDEEAGEQLAQNLNS-HGMKAHFELVDLTD 77

Query: 216 EEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLKAI 377
            E     + A ++  G I  ++NNAA      L   S   + + + VN+     +  K  
Sbjct: 78  IEMLKDKIQARLEAWGAIRALVNNAANDHRHTLAELSSDEFDQCMAVNLKHHFFAAQKVA 137

Query: 378 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
            +M +     GG++IN+SS + +      P Y   K+ +   +  + R      T VRV 
Sbjct: 138 PLMAE---AGGGSIINMSSNSWMLGLSGYPGYVTAKAGISGLTKALAR--ELGPTKVRVN 192

Query: 558 TVCFG 572
           TV  G
Sbjct: 193 TVLPG 197


>UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Verminephrobacter eiseniae EF01-2|Rep: Short-chain
           dehydrogenase/reductase SDR - Verminephrobacter eiseniae
           (strain EF01-2)
          Length = 265

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 55/197 (27%), Positives = 94/197 (47%), Gaps = 6/197 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  ITGA +GIG +   +   EG + I + D+  E G++  V    + G +  F ++DV
Sbjct: 16  KVALITGAGSGIGRATALLFATEGAQ-IVVCDLDPEGGQAT-VRAIEQAGAQALFVQADV 73

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 371
                    +   ++    +DV+ NNA +      ++ S   +   + VNV ++   + +
Sbjct: 74  AQAADCARAVQQTLRHFARLDVLFNNAGITCRANVVDTSEADWDAVMAVNVKSIFLMSRQ 133

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           A+ +M +  GG   ++IN  S   L        Y A K AV+  +  +   +H  +  +R
Sbjct: 134 AVPVMAEQGGG---SIINAGSGWGLVGGRDAVSYCAAKGAVVNMTRAMAL-DHGPQR-IR 188

Query: 552 VLTVCFGATDTALLTDE 602
           V +VC G TDTA+L DE
Sbjct: 189 VNSVCPGDTDTAMLRDE 205


>UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627;
           n=13; Bacteria|Rep: Uncharacterized oxidoreductase
           SSP1627 - Staphylococcus saprophyticus subsp.
           saprophyticus (strain ATCC 15305 /DSM 20229)
          Length = 246

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 66/222 (29%), Positives = 103/222 (46%), Gaps = 7/222 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 200
           KDKVV ITGA++GIGE  V +L + G K    L +       L+ ++  K G +     +
Sbjct: 5   KDKVVVITGASSGIGEETVNLLSENGAK----LVLGARRLDRLE-KIQQKVGHDSVSIKK 59

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 362
           +DVT  +    ++     + G IDV+INNA LM  S         + + I+VN+  ++  
Sbjct: 60  TDVTKPDEVNALIETAYNDFGRIDVLINNAGLMPQSFLEKNKQDEWNQMIDVNIKGVLYG 119

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
               +  M K    K G +IN++SVA         +Y  TK AV   +  + + E    +
Sbjct: 120 IGAVLPYMRKQ---KSGHIINLASVAGHVVFPGSAVYCGTKYAVRAITEGLRQEEAIVGS 176

Query: 543 GVRVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKKGFI 668
            +R   +  GA  T  LTD      DK ++   +D+L K  I
Sbjct: 177 NIRTTILSPGAVSTE-LTDH---ISDKDMKQD-IDELYKNAI 213


>UniRef50_P50197 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=8; root|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Pseudomonas paucimobilis (Sphingomonas paucimobilis)
          Length = 250

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 51/195 (26%), Positives = 94/195 (48%), Gaps = 7/195 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K + +TG  +GIG + V +L+  G  ++ + DI +EAG+++     +  G K  ++R D+
Sbjct: 7   KTIIVTGGGSGIGRATVELLVASGA-NVPVADINDEAGEAVV----ATSGGKAAYFRCDI 61

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 368
             EE    ++   +   GG+D   NNAA       L   S+  +++++++NVT   T   
Sbjct: 62  AQEEDVKALVAQTLAAFGGLDGSFNNAAIPQAGLPLAEVSLERFRQSMDINVTG--TFLC 119

Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
              +I+     G  G+++N +S A +    +   Y   K AV+  +        + K G+
Sbjct: 120 MKYQILAMIERGTKGSIVNTASAAGVVGVPMHGEYVGAKHAVVGLTRVAA--ADYGKHGI 177

Query: 549 RVLTVCFGATDTALL 593
           RV  +  GA  T +L
Sbjct: 178 RVNALVPGAVRTPML 192


>UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60;
           Bacteria|Rep: Sorbitol dehydrogenase - Rhodobacter
           sphaeroides (Rhodopseudomonas sphaeroides)
          Length = 256

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 52/188 (27%), Positives = 95/188 (50%), Gaps = 4/188 (2%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K   ITG+A GIG +     + EG + +AI DI  EA ++   E+    G        DV
Sbjct: 6   KTALITGSARGIGRAFAEAYVREGAR-VAIADINLEAARATAAEI----GPAACAIALDV 60

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDS--IGIYKKAIEVNVTALITSTLKAIEI 383
           TD+      +  ++   G ID+++NNAAL + +  + I +++ +      ++ TL  ++ 
Sbjct: 61  TDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFMMQA 120

Query: 384 MGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
           + +   +GG+GG +IN++S A      ++ +Y ATK+AV+  +   G   +  + G+ V 
Sbjct: 121 VARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGL--NLIRHGINVN 178

Query: 558 TVCFGATD 581
            +  G  D
Sbjct: 179 AIAPGVVD 186


>UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1;
           Oceanobacillus iheyensis|Rep: Hypothetical conserved
           protein - Oceanobacillus iheyensis
          Length = 254

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 60/197 (30%), Positives = 93/197 (47%), Gaps = 7/197 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KVV ITG A GIG++  ++LLD G K +A++DI E++    +  L+ +  ++      +V
Sbjct: 4   KVVLITGGAGGIGQATAKLLLDYGAK-VALVDINEDSLVKAKESLHVE-DDRVFTITGNV 61

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 368
           T EE     +   V   G IDV  NNA +      I       ++K + +NVT +     
Sbjct: 62  TVEEDVENYVKQTVDRFGKIDVFFNNAGVNGPVSPITELDQATFEKIMSINVTGVFLGLK 121

Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
             ++ M K      G+++N +S AA   S  M  Y A+K AV   +         +  G+
Sbjct: 122 HVMKQMKKQG---YGSIVNTASNAAYIGSAGMVSYIASKHAVAGITKTAAL--EVASDGI 176

Query: 549 RVLTVCFGATDTALLTD 599
           RV  V   A DT +L D
Sbjct: 177 RVNAVAPAAIDTQMLAD 193


>UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular
           organisms|Rep: Alcohol dehydrogenase - Bordetella
           parapertussis
          Length = 252

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 5/195 (2%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K   +TGA +G GE +      EG K + + DI E  G+ +   +N+  G +  F R+DV
Sbjct: 6   KTAIVTGAGSGFGEGIAATFAREGAK-VVVADINEAGGQRVAAAINAA-GGQAVFVRADV 63

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 389
           +D      +L A ++  GG+D+V+NNA   + +  +  +  E     +    +K+I +  
Sbjct: 64  SDNAAVANLLAATLKAFGGLDIVVNNAGTTHRNRPML-EVEEDEFDRIYAINVKSIYLTA 122

Query: 390 KH-----SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
           +H         GG+ IN++S AA+     +  Y  +K AV+  S  +          V  
Sbjct: 123 RHMVPHFRAHGGGSFINIASTAAIRPRPGLTWYNGSKGAVVTTSKSMAAELGPDNIRVNC 182

Query: 555 LTVCFGATDTALLTD 599
           +    GA  T LL D
Sbjct: 183 VNPVIGA--TGLLAD 195


>UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase
           precursor; n=2; Clostridium difficile|Rep: Probable
           short chain dehydrogenase precursor - Clostridium
           difficile (strain 630)
          Length = 245

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 50/216 (23%), Positives = 103/216 (47%), Gaps = 6/216 (2%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           K K V ITG A GIG+++ +    EG   +   + +E   K L   LN K     K +++
Sbjct: 2   KKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKELYTILNEK-NFSVKLFKA 60

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 365
           ++++ E    +++  ++E GG+DV++NNA +  D +        +   + +N+      +
Sbjct: 61  NISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITDEDWDNMMNINLKGSFYCS 120

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
             A++ M      K G +IN+SS+  ++ +     Y  TK+ ++  +  + +      + 
Sbjct: 121 QVALKYM---ISEKKGNIINISSIWGISGASCEVHYSITKAGIIGMTKALAK--EVGPSN 175

Query: 546 VRVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQL 653
           +RV ++  G  +T +L+       D  +E + L +L
Sbjct: 176 IRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRL 211


>UniRef50_O33454 Cluster: P-cumic alcohol dehydrogenase; n=3;
           Proteobacteria|Rep: P-cumic alcohol dehydrogenase -
           Pseudomonas putida
          Length = 252

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 60/194 (30%), Positives = 93/194 (47%), Gaps = 9/194 (4%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           KDKV  +TGAATGIG ++VR  L EG K + I D+  +  ++   EL     +      +
Sbjct: 4   KDKVAIVTGAATGIGNAIVRSYLAEGAK-VVIADV--KGAEAAAAELGE---DLALGVFA 57

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN-------DSIGI--YKKAIEVNVTALI 356
           DV+D +    +  A +   G IDV++NNA +         +SI +  + K   VNV    
Sbjct: 58  DVSDPDSTKQMAKAALDRFGKIDVLVNNAGIFTGLNYVPMESISVADWDKLYSVNVKG-- 115

Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
              L A  +      G GG +IN++SV A   +  M  Y ++K AV   +  + R    +
Sbjct: 116 -PWLCASAVSAAMREGGGGKIINIASVIAHIGAPFMLHYVSSKGAVAAMTRAMAREFATT 174

Query: 537 KTGVRVLTVCFGAT 578
           K G+ V ++  G T
Sbjct: 175 KAGISVNSISPGYT 188


>UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Roseiflexus sp. RS-1
          Length = 246

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 58/196 (29%), Positives = 92/196 (46%), Gaps = 5/196 (2%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           K KV  +TGA  GIG++       EG  H+A++DI   AG    V   ++   +    ++
Sbjct: 4   KGKVAIVTGAGHGIGKATAIAFAREGA-HVAVVDI-NMAGAEATVAEITRLDGRALAVQA 61

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 383
           DV+       ++  V+   G IDV++NNA +  D+  +  K  E    A+I   LK + +
Sbjct: 62  DVSQAASVESMVETVLAWGGRIDVLLNNAGITRDARLV--KMTEQQWDAVINVNLKGVWL 119

Query: 384 MGK----HSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
             +    H   +G G++INVSS+  L  +     Y ATK  V+  +    R      +GV
Sbjct: 120 CARAVAPHMSAQGSGSIINVSSIVGLYGNFGQSNYAATKGGVIAMTKTWAR--ELGPSGV 177

Query: 549 RVLTVCFGATDTALLT 596
           RV  V  G   T ++T
Sbjct: 178 RVNAVTPGFIATEMIT 193


>UniRef50_Q0D3V4 Cluster: Os07g0664000 protein; n=34; cellular
           organisms|Rep: Os07g0664000 protein - Oryza sativa
           subsp. japonica (Rice)
          Length = 572

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 58/197 (29%), Positives = 88/197 (44%), Gaps = 9/197 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  ITG A+GIG++     +  G K + I DI ++ G S+  EL    G    + R DV
Sbjct: 314 KVAVITGGASGIGKATATEFIKNGAK-VIIADIQDDLGHSVAAEL----GPDAAYTRCDV 368

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNA----ALMND-----SIGIYKKAIEVNVTALITS 362
            DE      +   V+  G +DV  NNA    AL  D      +G + + + VN  + + +
Sbjct: 369 ADEAQVAAAVGLAVKRHGRLDVFHNNAGIAGALPQDDMAAVDLGDFDRVMAVNARSTLAA 428

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
              A   M        G V+  SS A +     +P+Y  +K+ V+        P   ++ 
Sbjct: 429 VKHAARAMAPRC---SGCVLCTSSGAGVIPVPAVPVYSVSKATVIAIVRAAAEP--MARH 483

Query: 543 GVRVLTVCFGATDTALL 593
           G+RV  +  GAT T LL
Sbjct: 484 GLRVNAISPGATRTPLL 500


>UniRef50_Q9VU92 Cluster: CG8757-PA; n=3; Drosophila
           melanogaster|Rep: CG8757-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 266

 Score = 72.5 bits (170), Expect = 8e-12
 Identities = 58/216 (26%), Positives = 102/216 (47%), Gaps = 13/216 (6%)
 Frame = +3

Query: 21  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
           W +KV  ++GA+ GIG +  R L+  G+  + +    E   K L+  L+ +  ++    +
Sbjct: 18  WCNKVAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEK-LRSGLSLEQQSRLHAIK 76

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALM-------NDSIGIYKKAIEVNVTALIT 359
            D+T E+  L   +   ++ GG+DV+++NA ++        D     +  IE N+   + 
Sbjct: 77  CDITQEDQVLKAFDWTCRQLGGVDVLVSNAGIIGTGELSERDDGPAMRSTIETNIMGTVY 136

Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMP------IYFATKSAVLQFSNCIGR 521
              ++   M K  G +G  VI V+SVA     ++ P      IY ATK A+   +    +
Sbjct: 137 CVRESFRSM-KRRGTEGHVVI-VNSVAGYQVPNLGPQLPSLNIYPATKFALRAMNEIYRQ 194

Query: 522 PEHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYL 629
                KT VRV TV  G  DT +L ++  G   +++
Sbjct: 195 EFQRHKTAVRVSTVSPGIVDTVILPEQIQGIIKQHM 230


>UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Acidobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Acidobacteria bacterium
           (strain Ellin345)
          Length = 257

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 53/193 (27%), Positives = 93/193 (48%), Gaps = 3/193 (1%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  + G  TGIG ++   L D G   ++     E+   +   E+  + G +T    SDV
Sbjct: 10  KVAVVVGGTTGIGRAISFGLADAGADVVSTARREEQVNAAAD-EIERR-GRQTLRVCSDV 67

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAIEI 383
           T       + NAV+ +   +D+++N A     +  +     E N  +   +T  L+A ++
Sbjct: 68  TSRASIQSLCNAVLAKFQKVDILVNCAGTTKRTPTLTVSEDEWNKILDTNLTGALRACQV 127

Query: 384 MGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
            GKH   +G G +IN++S+++    H +  Y A+K+A+L  +  +     +SK GV V  
Sbjct: 128 FGKHMIERGYGRIINIASLSSFVALHEVAAYSASKAALLSLTRSLA--VEWSKKGVTVNA 185

Query: 561 VCFGATDTALLTD 599
           +  G   TAL T+
Sbjct: 186 IAPGVFRTALNTE 198


>UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain
           dehydrogenase/reductase SDR - Rubrobacter xylanophilus
           (strain DSM 9941 / NBRC 16129)
          Length = 251

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 58/203 (28%), Positives = 95/203 (46%), Gaps = 6/203 (2%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K   +TGA +GIG ++      EG + +A+ D+ E A + +  E+    G      R+DV
Sbjct: 7   KRTIVTGAGSGIGRAIALRFAAEGAR-VALADVDEGAARKVAAEI----GEGCLVQRTDV 61

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 371
           T  E   G++    +  GG++V++NNA +         S   +++ + VN+         
Sbjct: 62  TVAEEVEGLVRLATERWGGLEVMVNNAGVGVAATAPQTSEEDFERVLAVNLRGTFLGMKY 121

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           AI  + + SG  GG VIN+SS+AAL        Y A K  +L  +   G  +H  + GVR
Sbjct: 122 AIPAI-RDSG--GGAVINMSSIAALVGLKDRAAYSAAKGGILALTRA-GAIDHIHE-GVR 176

Query: 552 VLTVCFGATDTALLTDEKLGTFD 620
           V  +  G  +T  ++    G  D
Sbjct: 177 VNCIAPGTVETPWISRITAGYAD 199


>UniRef50_Q13H99 Cluster: Putative short-chain
           dehydrogenase/reductase; n=3; Proteobacteria|Rep:
           Putative short-chain dehydrogenase/reductase -
           Burkholderia xenovorans (strain LB400)
          Length = 274

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 53/201 (26%), Positives = 98/201 (48%), Gaps = 12/201 (5%)
 Frame = +3

Query: 6   KMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNK 185
           K   + ++KV  +TGA  G+G +  R L   G + +A++DI  EA  ++  ++    G +
Sbjct: 5   KAGGKLENKVAIVTGAGAGLGAACARALAQHGAR-VAVVDINGEAAAAVAADI----GER 59

Query: 186 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------------SIGIYKKA 329
               R+DV+ E     +++AV++  G ID++ NNAA+++D            S+ ++ +A
Sbjct: 60  AMSVRTDVSSEAQVKAMVSAVLEHFGRIDILHNNAAVLDDAQRAGDRDVINMSVEVWDRA 119

Query: 330 IEVNVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 509
           + VN+   +     AI  M +   G GG++I+ SS         M  Y A+K+ +   S 
Sbjct: 120 MAVNLRGAMLCCKHAIPAMLR---GGGGSIIHSSSGFGAQGDFTMSAYAASKAGLAMLSK 176

Query: 510 CIGRPEHFSKTGVRVLTVCFG 572
            +     + K  +R  T+  G
Sbjct: 177 SVA--AQYGKERIRSNTIQIG 195


>UniRef50_Q0M0K7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Caulobacter sp. K31|Rep: Short-chain
           dehydrogenase/reductase SDR - Caulobacter sp. K31
          Length = 249

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 54/200 (27%), Positives = 95/200 (47%), Gaps = 6/200 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           MS +   +V  +TGA++G GE+V   L   G K +A+    E+  ++L   +    G + 
Sbjct: 1   MSMDLSGRVALVTGASSGFGEAVALDLAKAGAK-VALAARREDRLRALAQRITDA-GGQA 58

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTA 350
           +   +D TDE      +       G +D++INNA +M         +G ++  +E+N+  
Sbjct: 59  QVIVADFTDEHQAQRAVRETEAAFGWLDILINNAGVMYLEPVATADLGRWRSMLELNLLG 118

Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
           LI +T  A+  M   +  K G ++N++S A    + +   Y A+K  V+ FS  + +  H
Sbjct: 119 LIAATQAALPGM---TARKDGHIVNIASTAGHIANPLSAAYSASKFGVIGFSESLRKEVH 175

Query: 531 FSKTGVRVLTVCFGATDTAL 590
             K  +RV  +  G   T L
Sbjct: 176 --KDNIRVTVISPGMAATEL 193


>UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Parvibaculum lavamentivorans DS-1|Rep: Short-chain
           dehydrogenase/reductase SDR - Parvibaculum
           lavamentivorans DS-1
          Length = 287

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 56/195 (28%), Positives = 95/195 (48%), Gaps = 8/195 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  ITG  +GIG   V + L EG K +A  D+ +  G++++ EL    G    + R++V
Sbjct: 7   KVAIITGGTSGIGRGTVDLFLKEGAKVVAA-DLQDHKGEAMEREL----GENFSYCRANV 61

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN-----VTALITSTLKA 374
             E+    +++  V++ G +D++ NNA      +G   + I++N     V  L+   +  
Sbjct: 62  AHEDEVKNLVDHTVKKFGKLDILFNNAGY--GGVGGELQEIDMNGFDETVGVLLKGVVLG 119

Query: 375 IEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNC--IGRPEHFSKTG 545
            +    H    K G++I+ +SVA L   +   +Y A K+AV  FS C  +    HF    
Sbjct: 120 YKYAVPHMKAQKSGSIISTASVAGLQAGYGPLVYSACKAAVHHFSRCAALELAPHF---- 175

Query: 546 VRVLTVCFGATDTAL 590
           VR   +C G   T++
Sbjct: 176 VRSNAICPGGIATSI 190


>UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=7; Gammaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Shewanella sp. (strain
           ANA-3)
          Length = 253

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 60/206 (29%), Positives = 96/206 (46%), Gaps = 8/206 (3%)
 Frame = +3

Query: 27  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
           +K   +TGAA GIG++++R LL EG + +A    A+ +  +L+V  N    +K   +  D
Sbjct: 5   NKTAVVTGAAGGIGQAIIRKLLAEGARVVA----ADLSADALKV-FNDFPADKLVTFSVD 59

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITST 365
           VTD +    ++     + G +D++INNA        L +D I  ++    VN   +    
Sbjct: 60  VTDYKQVEAMVKHAADQFGQLDILINNAGIGLAKPLLQHDPINDFEPVTNVNQKGVYHGI 119

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
           L         + G  G ++N SSV A   S +   Y  +K+AV   + C       +  G
Sbjct: 120 LAGGRQF--QAQGSRGVILNTSSVYAQIASEMTFTYNVSKAAVDMMTKCAAL--ELAPLG 175

Query: 546 VRVLTVCFGATDTALLTD-EKLGTFD 620
           VRV  V  G  DT +L   E LG ++
Sbjct: 176 VRVCAVAPGRVDTPMLRQYEALGLWE 201


>UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Shewanella woodyi ATCC 51908|Rep: Short-chain
           dehydrogenase/reductase SDR - Shewanella woodyi ATCC
           51908
          Length = 255

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 50/191 (26%), Positives = 94/191 (49%), Gaps = 6/191 (3%)
 Frame = +3

Query: 36  VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 215
           VFITG A+GIG ++VR  +++G  ++  +D   +AG++L   L+   G +  F+  DVTD
Sbjct: 15  VFITGGASGIGAALVRAFVEQGA-NVTFVDTNRDAGEALLQGLDINRGQQVAFHLLDVTD 73

Query: 216 EEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGI----YKKAIEVNVTALITSTLKAI 377
            +    ++    Q+ G +D++INN      +D+ G+    +K+ + +N+ +   ++  A 
Sbjct: 74  TKQLQQMITEQDQKLGQLDILINNVGNDSRHDADGVDEHEWKQCMAINLDSAFFASQAAY 133

Query: 378 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
            +M +    K G +IN SS  A      M  Y   K+ +   +  + +    S+  V  +
Sbjct: 134 LVMKQR---KQGVIINFSSNMAYIGERNMAGYITAKAGIAGMTKALAKDYGESRVRVNAI 190

Query: 558 TVCFGATDTAL 590
              + AT   L
Sbjct: 191 VPGWVATQRQL 201


>UniRef50_Q54D03 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 292

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 53/197 (26%), Positives = 93/197 (47%), Gaps = 6/197 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV F+TG A+GIG  +V   + EG K +AI+D+ +    +   ELN ++   T     DV
Sbjct: 36  KVCFVTGGASGIGLGIVERFVKEGGK-VAIVDLDKTKADNASKELNQRFPGSTISVECDV 94

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 371
           ++EE     +   V+  GG+DV+++NA L +        +  ++K + V++      T  
Sbjct: 95  SNEEQVSKGIKDTVERFGGLDVIVSNAGLQHIETLETVELATWRKMMAVHLDGAFLCTKY 154

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           A++   K    +GGT++ + SV +   S     Y   K  +     C G     +K  +R
Sbjct: 155 AMQEF-KKDIKRGGTILYMGSVHSKYASEYKIPYVTAKHGLEGL--CRGVAREGAKHNIR 211

Query: 552 VLTVCFGATDTALLTDE 602
              +C G   T L+ ++
Sbjct: 212 ANLICPGFVLTPLVKNQ 228


>UniRef50_Q22RI1 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=3;
           Oligohymenophorea|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family protein - Tetrahymena
           thermophila SB210
          Length = 260

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 58/219 (26%), Positives = 108/219 (49%), Gaps = 18/219 (8%)
 Frame = +3

Query: 33  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 209
           V  +TG  +G+GE+ V  LL++GV+ + I D  EE G    +++ +KYG ++ +F + DV
Sbjct: 8   VALVTGGTSGLGEATVYALLEKGVR-VFIADRNEEKG----LQIQTKYGQDRCRFQKCDV 62

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------------YKKAIEVNVTA 350
           +DE     +++A V   G I +++N+A +++  + +               + + VNV  
Sbjct: 63  SDEAQVKALVDACVATFGAIHILLNSAGVISAGLIVGGKNQDQTIKTEEMNRVLGVNVVG 122

Query: 351 LITST----LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIG 518
               T    L+ ++    +   + G ++NV+SVA +       +Y A+K A++  +  + 
Sbjct: 123 TFNVTKYVALQMVKQQPLNEFKERGVIVNVASVAGIEGQRGQTVYAASKGAIIGMTLPLA 182

Query: 519 RPEHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYLES 635
           R     K GVRV T+  G   T +      G  DK +E+
Sbjct: 183 R--DLGKFGVRVCTIAPGIFQTPM----GAGMSDKIIEA 215


>UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid
           dehydrogenase; n=28; Bacteria|Rep: 3-alpha-(or
           20-beta)-hydroxysteroid dehydrogenase - Mycobacterium
           bovis
          Length = 260

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 55/200 (27%), Positives = 98/200 (49%), Gaps = 6/200 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           MS     KV  ++G A G+G S VR ++ EG K +   DI +E GK++  EL     +  
Sbjct: 1   MSGRLIGKVALVSGGARGMGASHVRAMVAEGAK-VVFGDILDEEGKAVAAEL----ADAA 55

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTA 350
           ++   DVT    +   ++  V   GG+ V++NNA ++N       ++  +++ ++VN+T 
Sbjct: 56  RYVHLDVTQPAQWTAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTG 115

Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
           +       ++ M K +G   G++IN+SS+  L  +     Y ATK AV   +        
Sbjct: 116 VFLGIRAVVKPM-KEAG--RGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTAL--E 170

Query: 531 FSKTGVRVLTVCFGATDTAL 590
              +G+RV ++  G   T +
Sbjct: 171 LGPSGIRVNSIHPGLVKTPM 190


>UniRef50_UPI00015B572E Cluster: PREDICTED: similar to putative
           alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to putative alcohol dehydrogenase -
           Nasonia vitripennis
          Length = 240

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 44/152 (28%), Positives = 78/152 (51%), Gaps = 4/152 (2%)
 Frame = +3

Query: 27  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQ---VELNSKYGN-KTKF 194
           +KV  +T    GIG S   + L    +++A+LD+ +     +      L  ++G  K  +
Sbjct: 5   NKVAIVTDGLGGIGFSTYLLRLK--AQYVAVLDLPQNNSPHVVDGLKTLEEEFGKGKFGY 62

Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 374
           Y  +V + E F  +   VV+ +G +D+++ NAA+  D+       I+VN+  +I  TL A
Sbjct: 63  YHVNVANAESFAAVYAKVVEHKGYVDILVYNAAVAKDTE--IDLTIDVNLKGVIKGTLHA 120

Query: 375 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPI 470
           +E MG H   KGG V+N++S   L  +  + +
Sbjct: 121 VEQMGVHKNQKGGVVVNIASFLGLEHNKFLGV 152


>UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n=2;
           Bacillaceae|Rep: 2O-beta-hydroxysteroid dehydrogenase -
           Oceanobacillus iheyensis
          Length = 244

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 62/219 (28%), Positives = 108/219 (49%), Gaps = 10/219 (4%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           ++KV  ITG A G+G S VR+   EG K +   D+ EE G +L  EL    G   KF + 
Sbjct: 5   ENKVAIITGGARGMGASHVRLFAKEGAK-VVFTDLNEEGGLALANEL----GENVKFVKQ 59

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 365
           DVT+ + +  +++   +  G ++V++NNA       LM  +   Y+K I++N  ++    
Sbjct: 60  DVTNADDWETVISETEEAFGPVNVLVNNAGISLSIPLMEMTEEQYRKIIDINQVSVFLG- 118

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
           +KA+    + +G   G+++N+SS+  +    V   Y  +K AV   +            G
Sbjct: 119 MKAVVPSMQKAG--SGSIVNISSMNGIVAGAVG--YTDSKFAVRGATKAAA--VQLGGLG 172

Query: 546 VRVLTVCFGATDTALLTD----EKLGTFDKYLESSCLDQ 650
           +RV +V  G  +T ++T     E++  F K + S  + Q
Sbjct: 173 IRVNSVHPGVIETPMVTKGDAVEQIKEFAKQIPSKRMAQ 211


>UniRef50_Q5LMX2 Cluster: 20-beta-hydroxysteroid dehydrogenase,
           putative; n=25; Alphaproteobacteria|Rep:
           20-beta-hydroxysteroid dehydrogenase, putative -
           Silicibacter pomeroyi
          Length = 250

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 58/202 (28%), Positives = 93/202 (46%), Gaps = 8/202 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           K K V ITGA+ GIG    R+    G  ++ +L  + EA  +   E+    G++      
Sbjct: 5   KGKTVLITGASRGIGAEAGRVFAQAGA-NVVLLARSAEALAAQAAEI----GDRALALAC 59

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM--------NDSIGIYKKAIEVNVTALIT 359
           DV D     G +NA V   GG+DV+INNA ++        +D +G +  AI++N+  +  
Sbjct: 60  DVADAAQVAGAVNAAVSRFGGLDVLINNAGVIEPISHLASSDPVG-WGHAIDINLKGVYY 118

Query: 360 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSK 539
               A+ +M K     GGT++ VSS AA         Y A+K+     + C+   E    
Sbjct: 119 GMRAALPVMRK---AGGGTILTVSSGAAHNPVEAWSHYCASKAGAAMLTACLHLEE--GH 173

Query: 540 TGVRVLTVCFGATDTALLTDEK 605
            G+R + +  G   T +  + K
Sbjct: 174 HGIRAMGLSPGTVATQMQREIK 195


>UniRef50_Q11ZZ1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Polaromonas sp. JS666|Rep: Short-chain
           dehydrogenase/reductase SDR - Polaromonas sp. (strain
           JS666 / ATCC BAA-500)
          Length = 265

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 58/209 (27%), Positives = 104/209 (49%), Gaps = 7/209 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEE-AGKSLQVELNSKYGNK 185
           M  + K+K V +TG  + IG ++V     EG  HI I D+ E+ A K+ ++ L S   + 
Sbjct: 1   MDIDLKNKSVIVTGGGSNIGRAIVLGFAAEGA-HITIGDVDEQQAQKTAELALLSGAAS- 58

Query: 186 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA---LM---NDSIGIYKKAIEVNVT 347
            +  ++DVT  +    +  A V + GG+DV++NN     LM     +  +++K I +N  
Sbjct: 59  AQVVKTDVTQLDQVQAMFKAAVDKFGGVDVLVNNVGWDQLMFFTQTTPDLWQKIIAINYV 118

Query: 348 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527
            ++  T  A+++M   +    G+++++SS A+        +Y   K+A+  F   I +  
Sbjct: 119 GVLNCTKTALDLMIPRN---AGSIVSISSDASRQGEPREAVYGGVKAAINSFMKTIAKEN 175

Query: 528 HFSKTGVRVLTVCFGATDTALLTDEKLGT 614
              + G+R   VC G T  +  TDE  G+
Sbjct: 176 --GRYGIRCNVVCPGITIPS-TTDEVGGS 201


>UniRef50_A6W2S3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Gammaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Marinomonas sp. MWYL1
          Length = 256

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 65/216 (30%), Positives = 101/216 (46%), Gaps = 9/216 (4%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           KD+ VFI+G ATGIG ++V     +G K  A +D+ E+AG +L   L +K G   +F   
Sbjct: 13  KDRSVFISGGATGIGAAIVEAYAKQGAK-TAFVDLDEKAGTALAKRL-TKDGYDVRFEVC 70

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK---- 371
           D+TD + +   + A  +  G I V++NNAA  ND     +   E     L+   +K    
Sbjct: 71  DITDIQDYQSKIRAAAEVFGPITVLLNNAA--NDVRHSLESLTEERFDELVGVNIKHAMF 128

Query: 372 ---AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
              A+  M +  G  GG++IN  SV  +  +   P Y  +K+A    +  + R       
Sbjct: 129 AAQAVAPMMRKLG--GGSIINFGSVGWMMATAGYPTYGTSKAATHGLTRSLAR--DLGGF 184

Query: 543 GVRVLTVCFG--ATDTALLTDEKLGTFDKYLESSCL 644
           G+RV T+  G   T+  L         +K  +S CL
Sbjct: 185 GIRVNTLVPGWVMTEKQLRMWVDDAAEEKIKQSQCL 220


>UniRef50_A4TBK3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Mycobacterium|Rep: Short-chain
           dehydrogenase/reductase SDR - Mycobacterium gilvum
           PYR-GCK
          Length = 543

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 58/193 (30%), Positives = 86/193 (44%), Gaps = 4/193 (2%)
 Frame = +3

Query: 27  DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 206
           D +V +TGAA+GIG +        G   + I D+   AG      L +  G     Y  D
Sbjct: 274 DTLVAVTGAASGIGRATALAFAHHGAD-VVISDV-NAAGLDETARLVTSAGVHAYPYTVD 331

Query: 207 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALIT--STLKAIE 380
           V D          V  E G  DVV+NNA + +    +   A E +    I     +    
Sbjct: 332 VADAAAVEAFAEQVCAEHGVPDVVVNNAGVGHAGFFLDTPAEEFDRVLDINFGGVVNGCR 391

Query: 381 IMGKHSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
             GK     G GG ++NV+S+A+ T  +VM  Y  +K+AV  FS+C+ R E     G+ +
Sbjct: 392 SFGKRLADRGVGGHIVNVASMASYTPVNVMNAYCTSKAAVFMFSDCL-RAE-LDSFGIGL 449

Query: 555 LTVCFGATDTALL 593
            T+C G   T ++
Sbjct: 450 TTICPGFISTNIV 462


>UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Bacillus coagulans 36D1|Rep: Short-chain
           dehydrogenase/reductase SDR - Bacillus coagulans 36D1
          Length = 262

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 52/199 (26%), Positives = 93/199 (46%), Gaps = 7/199 (3%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
           ++  KV  +TG   GIG     + L  G  ++ + D+++E G+    ++    G +  F 
Sbjct: 5   DFTGKVAIVTGGGGGIGREAC-LKLAAGGANVVVADLSDELGEETAGKIREN-GGEAIFV 62

Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALI 356
           R+DV+  +     +   +   G ID+++NNA        L++    ++ K + +NV  + 
Sbjct: 63  RTDVSKSKDVQHYVRTALDTYGKIDILLNNAGWEGKMKPLIDYPEEVFDKLMGINVRGVF 122

Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
                 +  M      K GT++N +SVA L  +  M  Y A+K AV+  +   G     +
Sbjct: 123 LGMKYVLPHMISQ---KSGTIVNTASVAGLVGTPEMVAYGASKHAVIGMTKTAG--IEAA 177

Query: 537 KTGVRVLTVCFGATDTALL 593
            +GVRV  VC G  DT ++
Sbjct: 178 PSGVRVNAVCPGVVDTEMM 196


>UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=9; cellular organisms|Rep: Short-chain
           dehydrogenase/reductase SDR - Nocardioides sp. (strain
           BAA-499 / JS614)
          Length = 259

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 55/205 (26%), Positives = 95/205 (46%), Gaps = 8/205 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           M+   + +V  ITG  +GIG + V+  + EG K + I DI +  G  L  +L     +  
Sbjct: 1   MTGRIQGRVAVITGGCSGIGLATVQRFVQEGAK-VVIGDIDDARGHQLVEQLGG--ADVA 57

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA--------ALMNDSIGIYKKAIEVNV 344
            +   DVT +E    +        G +D+  NNA        ++++  +  ++K  EVN+
Sbjct: 58  TYVHVDVTSKEQVDALFQTAKDAYGSVDIAFNNAGISPPEDDSILDTDLDAWRKVQEVNL 117

Query: 345 TALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 524
           T++      A+  M +   G+G  +   S VA +  +     Y A+K  VL  +  +G  
Sbjct: 118 TSVYLCCKAALPHMLEQ--GRGSIINTASFVAVMGAATSQISYSASKGGVLSMTRELG-- 173

Query: 525 EHFSKTGVRVLTVCFGATDTALLTD 599
             F++ GVRV  +C G  +T LL +
Sbjct: 174 VQFARQGVRVNALCPGPVNTPLLQE 198


>UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=18; Bacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Arthrobacter sp.
           (strain FB24)
          Length = 263

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 59/208 (28%), Positives = 97/208 (46%), Gaps = 18/208 (8%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK-FYR 200
           K  V  ITG A+G+G +  R L D G   + ++D+    G++   ELN+  G  T  F  
Sbjct: 4   KGTVALITGGASGLGAATARRLFDAGAS-VVLVDLPSSRGEAFAAELNAASGAGTAVFVP 62

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS----------IGIYKKAIEVN--- 341
           +DVT EE     + A V   G + +V+N A +              +  + + I++N   
Sbjct: 63  ADVTSEEQVQAAVAAAVA-LGPLRIVVNCAGIATPGKVLGRDGVLPLDTFSRVIQINLVG 121

Query: 342 ---VTALITSTLKAIEIMGKHSGG-KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 509
              V  L  + + A E +    GG + G +IN +SVAA       P Y A+K AV   + 
Sbjct: 122 TFNVIRLAAAAMAATEPVSTELGGPERGVIINTASVAAFDGQIGQPAYAASKGAVAAMTL 181

Query: 510 CIGRPEHFSKTGVRVLTVCFGATDTALL 593
            I R    +++ +RV+T+  G  +T ++
Sbjct: 182 PIAR--ELARSLIRVVTIAPGIFETPMM 207


>UniRef50_A7S4C5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 306

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 63/222 (28%), Positives = 103/222 (46%), Gaps = 7/222 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           + + V ITGAA+GIG     IL  +G K + + DI  EA K++  E+    G +T ++  
Sbjct: 34  RGETVLITGAASGIGRLTALILAKKGCK-LVLWDINLEALKAVAQEIQD-LGAETHYFEC 91

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 365
           DV  ++    + NAV  + G + ++INNA +      +N S     +  +VN  A I + 
Sbjct: 92  DVRKKDEVEKVANAVEDQAGNVTILINNAGVVTGKKFLNCSESDVMRTFQVNSLAHIWTI 151

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH-FSKT 542
            + I  M + + G    +++++SVA          Y A+K A +     + R  H   K 
Sbjct: 152 QRFIPSMMEKNRGH---IVSIASVAGYFGLVGCVDYCASKFAAVGLIEALRREIHGLGKM 208

Query: 543 GVRVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKKGFI 668
           G+   T+C   T T +    KL    KY     L +LK  F+
Sbjct: 209 GIEFTTICPHFTATGMFAGVKL----KYPNLPGLGELKPEFV 246


>UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular
           organisms|Rep: Oxidoreductase - Halobacterium salinarium
           (Halobacterium halobium)
          Length = 260

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 58/200 (29%), Positives = 91/200 (45%), Gaps = 6/200 (3%)
 Frame = +3

Query: 15  HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF 194
           HE    V  +TGA++GIGE+    L  EG   +     A+E   +L   +    G+    
Sbjct: 16  HELAGDVAIVTGASSGIGEATAEALAAEGAHVVLAARRADELA-ALADRIEDTDGDAL-V 73

Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALI 356
             +D+TD++    +++  V E G ID+++NNA +M             ++ +EVN+  L+
Sbjct: 74  VPTDITDDDAIDDLVSETVDEYGRIDILVNNAGVMLLEPLERADRSNLRQMVEVNLLGLM 133

Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
             T   + IM     G    V+NVSSVA          Y ATK  V  F++ I   +  +
Sbjct: 134 NLTHAVVPIMQDQDAGH---VVNVSSVAGRQADADSSGYNATKFGVNAFTDAI--RQELT 188

Query: 537 KTGVRVLTVCFGATDTALLT 596
              +R   +  GA DT L T
Sbjct: 189 SQDIRTTIIEPGAVDTELST 208


>UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=1;
           Natronomonas pharaonis DSM 2160|Rep: Probable
           dehydrogenase/ reductase 4 - Natronomonas pharaonis
           (strain DSM 2160 / ATCC 35678)
          Length = 253

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 54/194 (27%), Positives = 86/194 (44%), Gaps = 4/194 (2%)
 Frame = +3

Query: 21  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
           +++  VFITGA +GIG +    +  EG   +A  DI E+ G+   V+     G    F+ 
Sbjct: 3   FENDTVFITGAGSGIGRATALKVAREGAFVVAT-DINEDGGRET-VDAVEDAGGDAAFHE 60

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI---GIYKKAIEVNVTALITSTLK 371
            DVTD + F  ++     E G +D +INNA + +       + +   E  +   +     
Sbjct: 61  LDVTDADEFKAVVETAADEYG-LDAMINNAGVGHPPAYTEDVTETTFEYVLDVNLRGVWN 119

Query: 372 AIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
             +    H   +G G ++NV S+A+        +Y  TK AVL  +  I       + GV
Sbjct: 120 GCQAALPHLKSQGEGAIVNVGSLASFLGLPKQAVYSLTKGAVLNLTRAIA--SEAGRDGV 177

Query: 549 RVLTVCFGATDTAL 590
           R   VC G  +T L
Sbjct: 178 RANAVCPGFIETPL 191


>UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34;
           Proteobacteria|Rep: Acetoacetyl-CoA reductase -
           Acinetobacter sp. (strain RA3849)
          Length = 248

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 50/197 (25%), Positives = 91/197 (46%), Gaps = 6/197 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           + KV  +TGA  GIG  + R L+  G K IA +   EE  +   ++      +  +F  +
Sbjct: 3   EQKVALVTGALGGIGSEICRQLVTAGYKIIATVVPREEDREKQWLQSEGFQDSDVRFVLT 62

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITST 365
           D+ + E     +   +  +G +DV++NNA +  D      S   + + I+ N+  L T T
Sbjct: 63  DLNNHEAATAAIQEAIAAEGRVDVLVNNAGITRDATFKKMSYEQWSQVIDTNLKTLFTVT 122

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
                +  K    K G ++N+SSV  L        Y A+K+ ++ F+  +   +  +++ 
Sbjct: 123 Q---PVFNKMLEQKSGRIVNISSVNGLKGQFGQANYSASKAGIIGFTKALA--QEGARSN 177

Query: 546 VRVLTVCFGATDTALLT 596
           + V  V  G T T ++T
Sbjct: 178 ICVNVVAPGYTATPMVT 194


>UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59;
           cellular organisms|Rep: Acetoin(diacetyl) reductase -
           Klebsiella pneumoniae
          Length = 256

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 54/193 (27%), Positives = 88/193 (45%), Gaps = 6/193 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  +TGA  GIG+++   L+ +G   +AI D  +   K++  E+N   G +    + DV
Sbjct: 3   KVALVTGAGQGIGKAIALRLVKDGFA-VAIADYNDATAKAVASEINQA-GGRAMAVKVDV 60

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMN----DSI--GIYKKAIEVNVTALITSTLK 371
           +D +     +    +  GG DV++NNA +      +SI   I  K   +NV  +I     
Sbjct: 61  SDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQA 120

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           A+E   K   G GG +IN  S A    +  + +Y ++K AV   +    R    +  G+ 
Sbjct: 121 AVEAFKKE--GHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAAR--DLAPLGIT 176

Query: 552 VLTVCFGATDTAL 590
           V   C G   T +
Sbjct: 177 VNGYCPGIVKTPM 189


>UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3;
           Clostridium|Rep: Bile acid 7-dehydroxylase 1/3 -
           Eubacterium sp. (strain VPI 12708)
          Length = 249

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 52/219 (23%), Positives = 101/219 (46%), Gaps = 7/219 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-YR 200
           +DK+  ITG   GIG +  ++ ++ G K ++I    +E   +   +L   Y  +    + 
Sbjct: 5   QDKITIITGGTRGIGFAAAKLFIENGAK-VSIFGETQEEVDTALAQLKELYPEEEVLGFA 63

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 362
            D+T  +  +  +  V Q+ G +DV+INNA +  +S+        +K  +++NV  +   
Sbjct: 64  PDLTSRDAVMAAVGTVAQKYGRLDVMINNAGITMNSVFSRVSEEDFKNIMDINVNGVFNG 123

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
              A + M      K G +IN +SV  +  S     Y  +K+ V+  ++ +GR     + 
Sbjct: 124 AWSAYQCM---KDAKQGVIINTASVTGIYGSLSGIGYPTSKAGVIGLTHGLGR--EIIRK 178

Query: 543 GVRVLTVCFGATDTALLTDEKLGTFDKYLESSCLDQLKK 659
            +RV+ V  G  DT +         + YL++  + ++ K
Sbjct: 179 NIRVVGVAPGVVDTDMTKGLPPEILEDYLKTLPMKRMLK 217


>UniRef50_Q89UC3 Cluster: D-beta-hydroxybutyrate dehydrogenase;
           n=11; Proteobacteria|Rep: D-beta-hydroxybutyrate
           dehydrogenase - Bradyrhizobium japonicum
          Length = 249

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 50/193 (25%), Positives = 91/193 (47%), Gaps = 4/193 (2%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           K   V +TGAA+G+G +  R+   EG  ++A+ D  E+   S+  E+ +  G   K ++ 
Sbjct: 2   KGLTVLVTGAASGMGRATARVFAAEGA-NVAVTDYDEQGAISVAKEIAAS-GGSAKAWKL 59

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIG--IYKKAIEVNVTALITSTLKA 374
           DV D      +++ V    GG+D+V+NNA + +  +I    Y+ A    +  ++T+  + 
Sbjct: 60  DVADGGEIKRVVHDVAAHFGGLDIVVNNAGISVRVAIDDETYEDAWARGIAVMLTAHPRI 119

Query: 375 IEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           I     H    K   ++N++S  AL  + +   Y A K  V   +  +       + G+ 
Sbjct: 120 IRAALPHLRKSKSPRIVNIASTEALGATALHSPYSAAKGGVASLTRSLA--VELGREGIT 177

Query: 552 VLTVCFGATDTAL 590
           V  +C G   TA+
Sbjct: 178 VNCICPGPIRTAI 190


>UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=1;
           Oceanobacter sp. RED65|Rep: Putative fatty acyl chain
           reductase - Oceanobacter sp. RED65
          Length = 252

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 48/194 (24%), Positives = 99/194 (51%), Gaps = 6/194 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K+V ITG +  +G + V     +  +     + ++++   L V    + G +    R ++
Sbjct: 10  KIVLITGGSGDLGRASVLEFGKQKCRVYFTYNSSKDSADEL-VASAEESGFEAFPIRCNI 68

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 371
           +D+E    ++N +V+++G IDV++NNA +  D++        +++ I+ N+      T  
Sbjct: 69  SDKEQVNALVNDIVEKEGKIDVLVNNAGIYKDNLFTSMTDEEFEQVIQTNLYGTFYCTKS 128

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
            +++M ++   + G ++NVSS+A +T S     Y A K AV+ FS  +      +   +R
Sbjct: 129 VVDVMYRN---RCGAIVNVSSIAGVTNSFGQANYSAAKGAVVSFSRTLA--AELAPKNIR 183

Query: 552 VLTVCFGATDTALL 593
           V TV  G  D++++
Sbjct: 184 VNTVAPGLIDSSMV 197


>UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 286

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 48/181 (26%), Positives = 88/181 (48%), Gaps = 6/181 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           +  F+TG   GIG ++  I L E   ++AILDI  E  +     +    G +   + +DV
Sbjct: 10  QAAFVTGGGGGIGRAIA-IRLAEAGANVAILDIIAERAEETATRIRET-GARALTFPADV 67

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLK 371
            + +     ++      G +D+++NNA        +  S    +K I++N+ +++ +T  
Sbjct: 68  MESDALRAAIDQAAAAFGRLDILVNNAGGVSARPFLEQSERSMRKHIDINLMSMLVATQA 127

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           A   M   +GGKGG++INV+S+ A   +    +Y A K+ +  F+  +      S  G+R
Sbjct: 128 AARHMV--AGGKGGSIINVASIEATRAAPNFAVYAACKAGMFSFTRSMAL--ELSGHGIR 183

Query: 552 V 554
           V
Sbjct: 184 V 184


>UniRef50_A5WHV5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Psychrobacter sp. PRwf-1|Rep: Short-chain
           dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1
          Length = 273

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 59/198 (29%), Positives = 96/198 (48%), Gaps = 10/198 (5%)
 Frame = +3

Query: 42  ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKY---GNKTKFYRSDVT 212
           +TGAA+GIG ++   LL +    +   DI  EA    Q+  N K    G      + DV 
Sbjct: 7   VTGAASGIGRALCERLLTDKGNQVCACDINYEA--LTQIYANHKLADAGGSLILRQLDVR 64

Query: 213 DEEHFLGILNAVVQEQGGIDVVINNAALMNDS----IGIYKKA---IEVNVTALITSTLK 371
           D + +  ++N V+ +   IDV+ N A ++ D+    I +        ++NV   I  T  
Sbjct: 65  DVQQWQEVVNTVIAQWQRIDVMCNIAGVLKDNWIADIALPDDVDLHFDINVKGTIFGTQS 124

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
            ++ M ++ G   G +INV+S+AAL+    + +Y A+K AV  +S   G      K G+ 
Sbjct: 125 VVDTM-RNQGS--GHIINVASLAALSPVPGLSLYSASKYAVRAYSLAAGM--ELEKYGIA 179

Query: 552 VLTVCFGATDTALLTDEK 605
           V T+C  A  T +L  +K
Sbjct: 180 VTTLCPDAVQTPMLDQQK 197


>UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Sphingomonadaceae|Rep: Short-chain
           dehydrogenase/reductase SDR - Novosphingobium
           aromaticivorans (strain DSM 12444)
          Length = 261

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 52/201 (25%), Positives = 99/201 (49%), Gaps = 8/201 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           MS +   KV  +TG + GIG +  R+L   G   + I    E+  ++ + E+ +K G K 
Sbjct: 1   MSQDMTGKVAIVTGGSDGIGLATARLLAARGAT-VVICARREDKLEAARAEI-AKVG-KV 57

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTA 350
           +  + DV+DE  F  ++  V    G +D+++NNA  ++ +      +  ++K   VN  A
Sbjct: 58  EAVKLDVSDEAAFTALVEDVAARHGRLDMLVNNAMSVHYAPIAKLRLDHWRKDFAVNADA 117

Query: 351 LITSTLKAIEIMG--KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRP 524
           +   T  A+++M   +  G + G ++N++S   +  +  M  Y A+K+A++ F+      
Sbjct: 118 VFVGTKAAMKVMAAQEQRGRQRGAIVNIASTCGIRAAPNMASYSASKAAMVHFTAAAAM- 176

Query: 525 EHFSKTGVRVLTVCFGATDTA 587
              +  G+RV  +  G   TA
Sbjct: 177 -EGAPLGIRVNAIVPGQVMTA 196


>UniRef50_A4ALI9 Cluster: Putative short chain dehydrogenase; n=2;
           Actinobacteria (class)|Rep: Putative short chain
           dehydrogenase - marine actinobacterium PHSC20C1
          Length = 265

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 56/192 (29%), Positives = 90/192 (46%), Gaps = 6/192 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           M+H  K++ V ITG  +GIG  +     + G + + + D++  A +S+  E+    G+  
Sbjct: 1   MTHPLKNQTVLITGGGSGIGRLLALGAAERGAR-VVVWDLSAAAAESVCEEILGA-GHHA 58

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTA 350
           + +  DV+D       +NA  ++ G +DV+INNA       L++ S    ++ I VN  A
Sbjct: 59  EAFTVDVSDRN----AVNAAAKKTGQVDVLINNAGIVTGKNLLDASDEAIERTIRVNTLA 114

Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
           L   T      +G     + GTV+ +SS A L        Y A+K A L F+  +     
Sbjct: 115 LFWVTRA---FLGNMIANRRGTVVTISSAAGLVGVAKQTDYSASKFAALGFAESLRVELS 171

Query: 531 FSKTGVRVLTVC 566
              TGV  L VC
Sbjct: 172 KENTGVNSLVVC 183


>UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales
           bacterium HTCC2150|Rep: Dehydrogenase - Rhodobacterales
           bacterium HTCC2150
          Length = 279

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 54/199 (27%), Positives = 96/199 (48%), Gaps = 7/199 (3%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDI-AEEAGKSLQVELNSKYGNKTKFYR 200
           K+K V +TGAA G+G +     L +G  ++ + D+ AE+  +S+Q  +  ++        
Sbjct: 23  KNKTVIVTGAAQGLGYACALRFLQDGA-NVVMADVNAEKLAESVQDLI--EFDGAVSSMV 79

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSIGIYKKAIEVNVTALITSTLKA 374
            DVT  E+   ++   V   G +DV+INNA +  + D + I     +  +   +      
Sbjct: 80  CDVTKRENLQALVGLAVSNYGNLDVMINNAGIAKVQDFLEISDDEYDAVMDVNLRGAFIG 139

Query: 375 IEIMGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN--CIGRPEHFSKT 542
            +I GK   + GKGG +IN+SS+ AL  + ++  Y  +K  + Q +N   +G   H    
Sbjct: 140 TQIAGKQMIAQGKGGVIINMSSINALVANPMLSTYAISKGGMNQLTNIAAVGLAPH---- 195

Query: 543 GVRVLTVCFGATDTALLTD 599
            +RV  +  G   T ++ D
Sbjct: 196 NIRVCGIGPGTILTDMVAD 214


>UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein; n=1;
           Algoriphagus sp. PR1|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein - Algoriphagus
           sp. PR1
          Length = 265

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 53/210 (25%), Positives = 106/210 (50%), Gaps = 8/210 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV+ +TG+ TGIG+++ + ++ EG K + I  + E+ G+ +  EL +   +  K +  D+
Sbjct: 6   KVIIVTGSTTGIGKAIAKKVVSEGAK-VIIHGLEEDLGQQVVSELGA---DNAKLHIEDI 61

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITSTLK 371
           ++E     +++  V+  G +D ++NNAA++  S           + +EVN  +    T  
Sbjct: 62  SNEGAAQRLVDIAVKTWGKLDSIVNNAAIVAASTLFDTDKAFLNRILEVNTISPFLLTQA 121

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           AI  + ++     G V+N+ S+ A +  H +  Y  +K A++  +  +G    F + GVR
Sbjct: 122 AISQLIQNK----GAVLNIGSINAYSGEHNLLAYSISKGALMTMTRNLG-DSLFRENGVR 176

Query: 552 VLTVCFG--ATDTALLTDEKLGTFDKYLES 635
           V  +  G   T+  +   ++ G  D + E+
Sbjct: 177 VNQINPGWVLTENEIARKKEHGLSDTWYEN 206


>UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 253

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 54/196 (27%), Positives = 89/196 (45%), Gaps = 5/196 (2%)
 Frame = +3

Query: 18  EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 197
           ++  KVV ITG ATGIG +       +G + + + D+ + A ++  V L  + G    F 
Sbjct: 6   DFTGKVVLITGGATGIGRATALAFAQQGAR-VVVGDVDDRAAET--VRLIEESGGTALFV 62

Query: 198 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 377
           R+DVT       ++   V   GG+ V  NNA ++  + G   +  E +    I   LK +
Sbjct: 63  RTDVTSAADVQQLVRTTVDTYGGLHVAFNNAGILPPT-GPLAEQSEDDFDRTIAVDLKGV 121

Query: 378 EIMGKH-----SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
            +  K+     +   GG++IN +SVA +     M  Y A K  V+  +        ++  
Sbjct: 122 FLALKYEIEHMAAAGGGSIINTASVAGVIADPGMAPYVAAKHGVVGLTRAAA--IDYAAA 179

Query: 543 GVRVLTVCFGATDTAL 590
           GVRV  +  G  DT +
Sbjct: 180 GVRVNALAPGLVDTPM 195


>UniRef50_A0Z215 Cluster: Short chain dehydrogenase; n=2;
           Gammaproteobacteria|Rep: Short chain dehydrogenase -
           marine gamma proteobacterium HTCC2080
          Length = 291

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 48/181 (26%), Positives = 85/181 (46%), Gaps = 2/181 (1%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K + ITGAA+G+G ++ +    EG   + I DI +E G  +  +LN +Y N   F   ++
Sbjct: 2   KRILITGAASGLGLALAKKYASEGWS-VCIADIQDEEGIKIAAQLNEEYANDCFFQHLNI 60

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGIYK-KAIEVNVTALITSTLKAIEI 383
           T +  +  ++  + +   G+D ++NNA +  +  I  +  K  +  V   +   +K   +
Sbjct: 61  TSDTQWQELVALISERWQGLDALVNNAGVGASGDIDTFSIKDFQWTVDINLMGAVKGCHV 120

Query: 384 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLTV 563
                    G +INV+S+A L     M  Y  +K+ ++ FS   G        GV+V  V
Sbjct: 121 CVPLLKESKGLLINVASMAGLLHMGSMSAYNVSKAGMVAFSE--GLLSELDPYGVKVSVV 178

Query: 564 C 566
           C
Sbjct: 179 C 179


>UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Stappia aggregata IAM 12614|Rep: Short-chain
           dehydrogenase/reductase SDR - Stappia aggregata IAM
           12614
          Length = 270

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 54/200 (27%), Positives = 95/200 (47%), Gaps = 8/200 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           +V  +TGA+ GIGE+  R L   G K + +   +++  + +  E+ ++ G        DV
Sbjct: 24  QVALVTGASRGIGEAAARSLAKYGAK-VVLAARSDKDIERIAGEIRAE-GQDATAVVCDV 81

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 368
            D +  +  +   V   GG+D+++NNA ++     I       + K I++NV  +     
Sbjct: 82  ADYDDVVKAVQTAVDTYGGLDILVNNAGVIEPIARIEDSDPAEWGKVIDINVKGVYYG-- 139

Query: 369 KAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
             +    KH   KG GTV+N+SS AA++       Y A+K+A L  + C  +   F   G
Sbjct: 140 --LHAAAKHMLAKGAGTVVNISSGAAVSALEGWSHYCASKAAALSLTRCADK--EFGDKG 195

Query: 546 VRVLTVCFGATDTALLTDEK 605
           +R++ +  G   T +  D K
Sbjct: 196 LRIVGLSPGTVATQMQVDIK 215


>UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family member
           10; n=19; Eumetazoa|Rep: Dehydrogenase/reductase SDR
           family member 10 - Homo sapiens (Human)
          Length = 270

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 61/195 (31%), Positives = 93/195 (47%), Gaps = 8/195 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KVV +TG   GIG  +VR  ++ G + + I D  E  G++L+ EL         F   DV
Sbjct: 10  KVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPG-----AVFILCDV 63

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 368
           T E+    +++  ++  G +D V+NNA            S   +++ +E+N+    T T 
Sbjct: 64  TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123

Query: 369 KAIEIMGKHSGGKGGTVINVSS-VAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
            A+  + K      G VIN+SS V A+ Q+  +P Y ATK AV   +  +   E  S  G
Sbjct: 124 LALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE--SPYG 176

Query: 546 VRVLTVCFGATDTAL 590
           VRV  +  G   T L
Sbjct: 177 VRVNCISPGNIWTPL 191


>UniRef50_P39071 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate
           dehydrogenase; n=31; Bacteria|Rep:
           2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase -
           Bacillus subtilis
          Length = 261

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 51/188 (27%), Positives = 90/188 (47%), Gaps = 3/188 (1%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K+ FITGAA GIGE+V R L  +G  HIA +D   E  + +   L ++     + + +DV
Sbjct: 9   KIAFITGAAQGIGEAVARTLASQGA-HIAAVDYNPEKLEKVVSSLKAE-ARHAEAFPADV 66

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI--GIYKKAIEVNVTALITSTLKAIEI 383
            D      I   + +E G ID+++N A ++   +   +  +  E   +   T    A   
Sbjct: 67  RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126

Query: 384 MGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVLT 560
           + K+    + G+++ V S  A      M  Y ++K+A + F+ C+G     ++  +R   
Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGL--ELAEYNIRCNI 184

Query: 561 VCFGATDT 584
           V  G+T+T
Sbjct: 185 VSPGSTET 192


>UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|Rep:
           Bll5898 protein - Bradyrhizobium japonicum
          Length = 256

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 61/201 (30%), Positives = 92/201 (45%), Gaps = 7/201 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           M   +KDKVV +TGA +GIG +  R    EG   I +L+   E   S   E+ ++ G   
Sbjct: 1   MLSRFKDKVVIVTGAGSGIGAAAARRFHGEGA--IVVLNGRRE---SKLAEVGAELGTDR 55

Query: 189 KFYR-SDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVT 347
              R +DVT       ++   V+  G ID+++NNA        +   I  ++    VNV 
Sbjct: 56  CMIRPADVTIAADVESLVADAVRRFGRIDILVNNAGTGALIDFLGSPIQQWRDLFAVNVD 115

Query: 348 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527
            ++  T  A+     H    GG+++NVSS++ L     +  Y ATK AV   +  +    
Sbjct: 116 GVLYMTRAAL----PHLIESGGSIVNVSSLSGLGGDRGLSFYNATKGAVSNLTRSLAL-- 169

Query: 528 HFSKTGVRVLTVCFGATDTAL 590
            F   GVR+  VC   T T L
Sbjct: 170 EFGPRGVRINAVCPSLTLTHL 190


>UniRef50_A6VY27 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Marinomonas sp. MWYL1
          Length = 252

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 64/226 (28%), Positives = 106/226 (46%), Gaps = 9/226 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           ++++  +K   +TG A+GIG + V +L   G   +AI D+ EEA +  +  + SKY  K 
Sbjct: 2   INYQLDNKKAMVTGGASGIGLACVELLAYSGAD-VAIWDLHEEALEKAKQSI-SKYNVKC 59

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI--GIYK-----KAIEVNVT 347
              + DV+D E     +   +++ G +D+ +NNA +   +   G Y      K I+VN  
Sbjct: 60  ITIKVDVSDPESVKAAMAETLKQLGSLDIAVNNAGIGGPACKSGDYTTEDWLKVIDVNFN 119

Query: 348 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPE 527
            +     +AI  M K+     G++IN++S+         P Y + K  V+  S      E
Sbjct: 120 GVFYCQREAIAAMRKNG---SGSIINMASILGQVAFPSSPAYVSAKHGVVGMSKA-SAVE 175

Query: 528 HFSKTGVRVLTVCFGATDTALLTDEKLG--TFDKYLESSCLDQLKK 659
           H ++  +RV  V  G   T L+ DE L   T D   +   L +L K
Sbjct: 176 H-AEDNIRVNAVGPGFIHTPLV-DEHLDAETLDMLAQKHALKRLGK 219


>UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2;
           Bacteria|Rep: Cyclopentanol dehydrogenase -
           Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 355

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 57/194 (29%), Positives = 92/194 (47%), Gaps = 6/194 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  ITG A G GE+  R+    G  H+ I D+ EE G+ L  EL    G +  F   DV
Sbjct: 102 KVALITGGARGQGEAEARLFAQHGA-HVYICDVLEEEGEKLAAELRGS-GLQADFRFLDV 159

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAAL-----MNDSIG-IYKKAIEVNVTALITSTLK 371
           TD E +   +  +    G +DV+INNA +     + D+    + + + VN    +   ++
Sbjct: 160 TDAEQWSRTVAHIDAGAGRLDVLINNAGINVRHQLTDTTSEEWDRIVAVNTKGQMLG-MQ 218

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           A   + K SG   G++IN+ S A +   H +  Y A+K AV   +         + +G+R
Sbjct: 219 ACAPLMKRSG--NGSIINIGSTAGI-MGHPVAAYSASKWAVRGLTKAAAM--ELASSGIR 273

Query: 552 VLTVCFGATDTALL 593
           V  +  G  +T ++
Sbjct: 274 VNAMHPGVVETPMV 287


>UniRef50_A0PSR4 Cluster: Short-chain dehydrogenase; n=1;
           Mycobacterium ulcerans Agy99|Rep: Short-chain
           dehydrogenase - Mycobacterium ulcerans (strain Agy99)
          Length = 282

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 55/191 (28%), Positives = 90/191 (47%), Gaps = 4/191 (2%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           +VV ITGA +GIG  +  +    G   +A+ DI + A      +    +G+     R DV
Sbjct: 16  RVVAITGAGSGIGRELALLCAQRGAD-LALCDINDTAVADT-AQTARGFGHDVITRRVDV 73

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITSTLKAIE- 380
           +D E      +A +   GG+D+++NNA   L+   +   +K  +  V+  +   +   E 
Sbjct: 74  SDPEQMTAFADATLGHFGGVDLLVNNAGVGLIGGFLDTSRKDWDWLVSINVMGVVHGCEA 133

Query: 381 -IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRVL 557
            +      G+GG V+N+SS A L  +  +  Y ATK AVL  S  + R E      + V 
Sbjct: 134 FLPAMIESGRGGHVVNLSSAAGLLANPALSAYSATKFAVLGLSEAL-RIE-LEPHRIGVT 191

Query: 558 TVCFGATDTAL 590
            +C G  +TA+
Sbjct: 192 AICPGVINTAI 202


>UniRef50_Q6NNV7 Cluster: RH03309p; n=4; melanogaster subgroup|Rep:
           RH03309p - Drosophila melanogaster (Fruit fly)
          Length = 247

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 52/204 (25%), Positives = 99/204 (48%), Gaps = 13/204 (6%)
 Frame = +3

Query: 21  WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 200
           W + V  +TGA++GIG ++ R L+  GV  +A+    +   + L+ EL     ++ +  +
Sbjct: 4   WHNCVAVVTGASSGIGAAITRKLISAGVMVVALARRMDRL-EQLREELPQDRRSRLRIMQ 62

Query: 201 SDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITS 362
            DV+D      + +AV  + G +D++INNA       L+  S+   ++ ++ NV  ++  
Sbjct: 63  CDVSDVSSVNAVFDAVQGDLGNVDILINNAGKLSGGQLLTMSVDTVQQMLQTNVMGVVYC 122

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMP-------IYFATKSAVLQFSNCIGR 521
           T +A E M +      G V+ ++S+      + +P       +Y ATK A+   +    +
Sbjct: 123 TQRAFESMRQRQ--SKGHVVLINSIVGHYIFNPLPGSQQELNMYPATKHAITALTELFRQ 180

Query: 522 PEHFSKTGVRVLTVCFGATDTALL 593
                KT V+V ++  G  DT L+
Sbjct: 181 EMRDFKTKVKVTSISPGLVDTELV 204


>UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein]
           reductase; n=26; Bacteria|Rep:
           3-oxoacyl-[acyl-carrier-protein] reductase - Chlamydia
           pneumoniae (Chlamydophila pneumoniae)
          Length = 248

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 52/197 (26%), Positives = 95/197 (48%), Gaps = 7/197 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K V +TG + GIG  +V++ L+ G   + I  + EE G+++ +E  +  G +  F R DV
Sbjct: 8   KKVIVTGGSRGIGLGIVKLFLENGAD-VEIWGLNEERGQAV-IESLTGLGGEVSFARVDV 65

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 371
           +        +   + +   ID+++NNA +  D++ +      ++  I  N+T+L  +   
Sbjct: 66  SHNGGVKDCVQKFLDKHNKIDILVNNAGITRDNLLMRMSEDDWQSVISTNLTSLYYTCSS 125

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
            I  M K    + G++INV+S+ A   S     Y A K+ ++ F+  + +        V 
Sbjct: 126 VIRHMIK---ARSGSIINVASIVAKIGSAGQTNYAAAKAGIIAFTKSLAKEVAARNIRVN 182

Query: 552 VLTVCFGATD-TALLTD 599
            L   F  TD T++L D
Sbjct: 183 CLAPGFIETDMTSVLND 199


>UniRef50_Q62E12 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol
           dehydrogenase; n=25; Proteobacteria|Rep:
           2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase -
           Burkholderia mallei (Pseudomonas mallei)
          Length = 265

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 48/170 (28%), Positives = 88/170 (51%), Gaps = 8/170 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG-KSLQVELNSKYGNKTKFYR-S 203
           K  FITGAA G+G ++ R + ++G + + + DI + A  ++   ELN   G +  +    
Sbjct: 14  KRAFITGAAGGLGRAIARRMAEQGAQ-VFLTDIVDAAVLEAFAAELNDTAGERIAWAAVQ 72

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN-DSIG-----IYKKAIEVNVTALITST 365
           DV DE  +   L+      GG+ V+++NA + +  +IG      +++ + +NV +++  T
Sbjct: 73  DVADEAQWASRLSQAADAMGGLSVLVHNAGVGSFGAIGQIARDEWRRVMAINVESIVLGT 132

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCI 515
             A+  +     G   +++N+SSVAA  Q      Y A+K+AV   +  I
Sbjct: 133 KHALPYL---EAGAPASIVNISSVAAFKQEPDYTAYNASKAAVASLTKSI 179


>UniRef50_Q2S7V4 Cluster: Short-chain alcohol dehydrogenase-like
           protein; n=1; Hahella chejuensis KCTC 2396|Rep:
           Short-chain alcohol dehydrogenase-like protein - Hahella
           chejuensis (strain KCTC 2396)
          Length = 288

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 53/198 (26%), Positives = 94/198 (47%), Gaps = 6/198 (3%)
 Frame = +3

Query: 15  HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF 194
           H + +K V ITGAA+G+G +  R  L  G + +A  D+ +E G ++   L     N+  +
Sbjct: 2   HRFPEKRVAITGAASGLGLATARHFLSRGWR-VAFADVQDETGSAIVASLGLP-ENRAFY 59

Query: 195 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIG-----IYKKAIEVNVTALI 356
              DVT           +V+  GG+D++INNA +  +  IG      ++  I++++  ++
Sbjct: 60  QHVDVTKVRDIQAWRRKIVETWGGLDILINNAGVAAHGGIGEAPLEDWEWVIDIDLMGVV 119

Query: 357 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFS 536
               +   +  +    + G ++N++S+A L  +  M  Y A K+ V+  S  +      S
Sbjct: 120 RGCKEFAPLFKRQ---RSGQIVNIASMAGLVHAPEMGSYNAAKAGVVALSETL--VGELS 174

Query: 537 KTGVRVLTVCFGATDTAL 590
             GV V  VC G   T L
Sbjct: 175 PFGVGVNVVCPGFFSTGL 192


>UniRef50_Q3EU48 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=1; Bacillus thuringiensis serovar
           israelensis ATCC 35646|Rep: 3-oxoacyl-[acyl-carrier
           protein] reductase - Bacillus thuringiensis serovar
           israelensis ATCC 35646
          Length = 252

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 47/201 (23%), Positives = 96/201 (47%), Gaps = 6/201 (2%)
 Frame = +3

Query: 24  KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 203
           ++K + +TG   GIG ++V   L EG    A    ++++   ++ EL S Y ++   Y  
Sbjct: 11  ENKRIIVTGGCKGIGRAIVEKYLQEGAVVAATYYKSKDSSDQMKSELES-YSDRLAIYNM 69

Query: 204 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITST 365
           DV+D E    ++  +  +  GID+++NN+ +  DS+        + K I+ N+     + 
Sbjct: 70  DVSDAEQVNKVMEQIQDDLKGIDILVNNSGITQDSLLYSMKNSDWDKVIKTNLYGPFYTC 129

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
              +  M K    K G++IN++SV+ +        Y A+K  ++  +  + +    +   
Sbjct: 130 KSVLLNMIKQ---KYGSIINIASVSGIVGIPGQSNYCASKFGLIGLTKSLAK--ELASKN 184

Query: 546 VRVLTVCFGATDTALLTDEKL 608
           +RV  +  G  DT ++ + K+
Sbjct: 185 IRVNAIAPGYVDTEMIDNVKI 205


>UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Caulobacter sp. K31|Rep: Short-chain
           dehydrogenase/reductase SDR - Caulobacter sp. K31
          Length = 254

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 56/194 (28%), Positives = 98/194 (50%), Gaps = 7/194 (3%)
 Frame = +3

Query: 3   LKMSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN 182
           + ++   K KV  ITGAA G+GE++ R  +  G   + I D+  E G+++  ++ ++ G 
Sbjct: 1   MSVNDSLKGKVAIITGAAQGLGEAIAREFVARGAA-VIITDVQREEGEAVAADILAQ-GG 58

Query: 183 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNV 344
           K  F   DV D E +  ++   +   G +DV++NNA L+  +      I ++ +   VNV
Sbjct: 59  KALFIAHDVGDAEAWDVVVAKALDTFGKVDVLVNNAGLIQFAPLEEMPIEMFDRVTRVNV 118

Query: 345 TALITSTLKAIEIMGKHSGGKGGTVINVSSV-AALTQSHVMPIYFATKSAVLQFSNCIGR 521
                   KAI    K +G  GG +IN+SS+   + Q+  +  Y  +K AV   +  +  
Sbjct: 119 RGPWLG-CKAILPALKAAG--GGAIINMSSMNGMIAQNPGLSAYATSKGAVRMLTKAVA- 174

Query: 522 PEHFSKTGVRVLTV 563
            + + + GVRV +V
Sbjct: 175 -QDYVQYGVRVNSV 187


>UniRef50_A4T9G9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Mycobacterium gilvum PYR-GCK|Rep: Short-chain
           dehydrogenase/reductase SDR - Mycobacterium gilvum
           PYR-GCK
          Length = 260

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 55/199 (27%), Positives = 98/199 (49%), Gaps = 9/199 (4%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K V ITGAA+GIG +  ++++ EG + + I D+  +A  +   ++    G       ++V
Sbjct: 9   KRVVITGAASGIGRAAAQLMIGEGAR-VLIADLDADAAAAAASDI----GGNAIGVAANV 63

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAA---------LMNDSIGIYKKAIEVNVTALITS 362
            D++    +++  V E GGIDV+ N+           L+   +  + +A+ +N  + + +
Sbjct: 64  LDDKSVAAMIDRAVTEFGGIDVLCNHVGGSNPHKDLDLLRLDLDEWDRAMALNARSTVVA 123

Query: 363 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
           +  A+  M    GG   ++IN  SVA LT   +   Y A+K+AV++ +  I     + + 
Sbjct: 124 SRLALPHMIAEGGG---SIINTVSVAGLTGDTLQCAYGASKAAVIRLTQYIA--TQYGRK 178

Query: 543 GVRVLTVCFGATDTALLTD 599
           GVR   V  GA  T  L D
Sbjct: 179 GVRCNAVAPGAVMTPALAD 197


>UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=3;
           Proteobacteria|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family protein - Erythrobacter
           sp. NAP1
          Length = 267

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 53/182 (29%), Positives = 90/182 (49%), Gaps = 7/182 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           K V ITG++ GIGE + R    EG   +     AE+  K     L++   ++T     DV
Sbjct: 10  KTVIITGSSAGIGEGIARRFHAEGANVVINARNAEKCAKVADT-LDA---DRTLTCPGDV 65

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-------KAIEVNVTALITSTL 368
           +  +    I+   V+  GG+D ++NNA +   S+ ++K       + I++NV  +I    
Sbjct: 66  SSSDFANEIVAKTVERFGGLDCLVNNAGVGGSSM-LHKTDDEEIDRIIDINVKGVIYLCR 124

Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
            AI  + K     GG++IN+SSV+ +    ++PIY A+K A+   +   G  +     G+
Sbjct: 125 AAIPHLRKSEAVGGGSIINISSVSGIGGDSMLPIYNASKGAMTNLTR--GLAQQIGGMGI 182

Query: 549 RV 554
           RV
Sbjct: 183 RV 184


>UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein; n=3;
           Bacteroidetes|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein - Polaribacter
           dokdonensis MED152
          Length = 257

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 62/216 (28%), Positives = 109/216 (50%), Gaps = 13/216 (6%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  ITG++ GIG+++ + L ++G + + I    +EA   +  E   + G  T      +
Sbjct: 12  KVAVITGSSKGIGKAIAKGLAEQGAQ-VVISSRNQEACDEVAKEFKEQ-GLDTIGIACHI 69

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG--------IYKKAIEVNVTALITST 365
             E+    +++  ++  G ID+++NNAA+ N   G        I+ K ++VNV A    +
Sbjct: 70  GKEDQRKNLVDKTIESFGRIDILVNNAAI-NPVFGPIEEVSPEIFDKIMDVNVKA--PWS 126

Query: 366 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTG 545
           L  + ++      K G++IN++SV ALT    + IY  +K+A+L  +    + + + K G
Sbjct: 127 LSNL-VLPHFQTNKNGSIINIASVEALTPGLGLGIYSTSKAAILMLTK--NQAKEWGKYG 183

Query: 546 VRVLTVCFGATDT----ALLTDEK-LGTFDKYLESS 638
           V+   +C G   T    AL  +EK L   +K L SS
Sbjct: 184 VKANAICPGLIKTKFSAALWQNEKILSKVEKALPSS 219


>UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=6; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Paracoccus
           denitrificans (strain Pd 1222)
          Length = 253

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 52/195 (26%), Positives = 91/195 (46%), Gaps = 7/195 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           M    KDKVV ITGA  GIG +  ++ ++EG + + + D   +A + +  EL    G   
Sbjct: 1   MDMHLKDKVVLITGAGAGIGAATAKLFIEEGAR-VVVADYLGDAAEQVAAEL----GENA 55

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 350
           + +  DV+  E    +++  V E GG+DV++NNA       +       ++  I+VN+T 
Sbjct: 56  RAFTVDVSKAEACKAMVDFTVAEFGGLDVLVNNAGRGSLGTVETQDENDWRSIIDVNLTG 115

Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQS-HVMPIYFATKSAVLQFSNCIGRPE 527
           +   +  A+  + K     GG ++N +S  A+  +      Y A K  V   +  +    
Sbjct: 116 VYLCSKYAVPELRKRG---GGAIVNTASNIAMAMAIRDRAAYVAAKGGVASLTRAMAL-- 170

Query: 528 HFSKTGVRVLTVCFG 572
            F+   +RV +V  G
Sbjct: 171 DFAADNIRVNSVAPG 185


>UniRef50_Q2FSZ0 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Methanospirillum hungatei JF-1|Rep: Short-chain
           dehydrogenase/reductase SDR - Methanospirillum hungatei
           (strain JF-1 / DSM 864)
          Length = 274

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 57/200 (28%), Positives = 98/200 (49%), Gaps = 6/200 (3%)
 Frame = +3

Query: 9   MSHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT 188
           MS  ++ KV  +TG  +GIG +V   LL  G     I    E   K+ +    + Y N T
Sbjct: 1   MSDVFEGKVAIVTGGTSGIGYAVSEELLKRGATVWVIGSRQESVDKARKSF--AAYKN-T 57

Query: 189 KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MND-----SIGIYKKAIEVNVTA 350
           +F   DVT  +   G+++A V++ G +D + NNA + M       ++ ++++AI++N+  
Sbjct: 58  RFLAVDVTVADQVKGMIDACVEKDGRLDYLFNNAGIGMTHPSQYLTLEMWQQAIDLNLWG 117

Query: 351 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEH 530
           ++     A+ +M      K G ++N SS+A +        Y ATK AV   +  + R E 
Sbjct: 118 VVYGVHFALPVM---LAQKSGHIVNTSSIAGIVPLPSQAAYCATKHAVTALTESL-RYEF 173

Query: 531 FSKTGVRVLTVCFGATDTAL 590
           F + G+   T+C     TA+
Sbjct: 174 FEE-GIAFTTICPSNVATAI 192


>UniRef50_Q48I17 Cluster: 3-oxoacyl-[acyl-carrier protein]
           reductase; n=1; Pseudomonas syringae pv. phaseolicola
           1448A|Rep: 3-oxoacyl-[acyl-carrier protein] reductase -
           Pseudomonas syringae pv. phaseolicola (strain 1448A /
           Race 6)
          Length = 282

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 59/198 (29%), Positives = 101/198 (51%), Gaps = 6/198 (3%)
 Frame = +3

Query: 33  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVT 212
           VV ITGAA GIG+++   L+  G++ I + DI E   K L+V L    G     Y  D+T
Sbjct: 4   VVLITGAAGGIGQAICAQLIRRGMQLI-LADIDE---KQLRV-LAESLGEDAFPYVVDLT 58

Query: 213 DEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTLKA 374
           ++E   G++  +  E G +DV+INNAA+         S+    + + +N+ A +  T  A
Sbjct: 59  NQESLAGLMTYIESEFGRLDVLINNAAIAVVEAFDTRSVESISRELNINLVAPLILTRLA 118

Query: 375 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVRV 554
           I ++ + +  +   VI+  S+  +  +   PIY A+K  +      IG     ++ G++V
Sbjct: 119 IPLLKRSNDAR---VISTVSLGGVFPTPESPIYCASKFGLRGAMLSIGL--DLAEKGIKV 173

Query: 555 LTVCFGATDTALLTDEKL 608
            ++   ATDT +L  E +
Sbjct: 174 GSILPTATDTQMLRKEAI 191


>UniRef50_Q02AD5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Solibacter usitatus Ellin6076|Rep: Short-chain
           dehydrogenase/reductase SDR - Solibacter usitatus
           (strain Ellin6076)
          Length = 261

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 58/205 (28%), Positives = 98/205 (47%), Gaps = 13/205 (6%)
 Frame = +3

Query: 33  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVT 212
           +  ITGA++GIG  + R+   +G   I +    +   + L  EL + +  K +   +D+ 
Sbjct: 5   MALITGASSGIGAELARLCAADGYGLILVARRTDRL-EQLGAELAAAHNVKFRTIAADLA 63

Query: 213 DEEHFLGILNAVVQEQGG--IDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 368
           + +       A+ ++  G  ID++INNA                 + I+VN+TAL   T 
Sbjct: 64  EPD----AATAIYRQTSGDTIDILINNAGFGLRGRYDQTEWNAEARLIQVNITALAQLTK 119

Query: 369 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGV 548
             ++ M +   G+   ++NV S AA     +M +Y+A+K+ V+ FS  + +   F  TGV
Sbjct: 120 SYVKDMVRRGSGR---ILNVGSTAAFVPGPLMAMYYASKAFVVSFSEALAK--EFEGTGV 174

Query: 549 RVLTVCFGATDT-----ALLTDEKL 608
            V  +C G T T     A +TD KL
Sbjct: 175 TVTVLCPGPTRTEFDAAAGITDSKL 199


>UniRef50_A5V545 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Sphingomonas wittichii RW1|Rep: Short-chain
           dehydrogenase/reductase SDR - Sphingomonas wittichii RW1
          Length = 264

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 54/194 (27%), Positives = 94/194 (48%), Gaps = 6/194 (3%)
 Frame = +3

Query: 30  KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 209
           KV  ITG  TGIG ++ R+   +G   +   ++A EA   + VE     G        D+
Sbjct: 5   KVAIITGGGTGIGAAIARLFARKGAHVVITSELAAEAMAPV-VEAIRADGGSASAMSCDI 63

Query: 210 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGIYKKAIE----VNVTALITSTLK 371
            D      ++  V ++ G ID++I +A +        +  + I+    VNV   I+    
Sbjct: 64  MDRAAIAALVEGVERDHGRIDILIQSAGVCFAGPIETMEPRKIDLTFGVNVIGAISMIQA 123

Query: 372 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKTGVR 551
           A+  M K +GG  G ++N+SS AA+   + M +Y A+K+A+  F+  +  PE   +T +R
Sbjct: 124 ALPAM-KRAGG--GAIVNISSGAAVLGVNEMAVYAASKAAIAHFTRTLA-PE-LRRTNIR 178

Query: 552 VLTVCFGATDTALL 593
           +  +  G+  T +L
Sbjct: 179 INAIGPGSVRTQML 192


>UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Polaromonas
           naphthalenivorans (strain CJ2)
          Length = 286

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 57/207 (27%), Positives = 102/207 (49%), Gaps = 11/207 (5%)
 Frame = +3

Query: 33  VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVT 212
           V  +TGAA GIG +  + L  +G++ +A+LD+  +A ++   EL S +         DVT
Sbjct: 21  VAIVTGAADGIGWATAQRLAADGLR-VALLDLRADAAQARAAELGSIHLG----LGCDVT 75

Query: 213 DEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNV--TALITST 365
            EE     + AV++  G ID ++NNA +          S+  + + + V++  T L++  
Sbjct: 76  SEESVEAAVAAVLERFGRIDALVNNAGIGDQTGPTTEQSVQAFDRVLAVHLRGTFLMSRA 135

Query: 366 LKAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCIGRPEHFSKT 542
           +    +      G+G G ++N+ S+A+ T       Y A K+ VL  +  +     +++ 
Sbjct: 136 VARHMLQAAPVPGRGRGAIVNLGSIASSTGLPARNAYSAGKAGVLGMTRAMA--SEWARA 193

Query: 543 GVRVLTVCFGATDTALLTD-EKLGTFD 620
           G+RV  V  G   TAL+ + E+ G  D
Sbjct: 194 GIRVNAVAPGYVRTALVAELERKGAID 220


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 658,888,275
Number of Sequences: 1657284
Number of extensions: 13125401
Number of successful extensions: 46075
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 41735
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 43502
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 51652897375
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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