Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30107
(778 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q19749 Cluster: Dihydrolipoyllysine-residue acetyltrans... 176 6e-43
UniRef50_P10515 Cluster: Dihydrolipoyllysine-residue acetyltrans... 143 5e-33
UniRef50_Q5DAY9 Cluster: SJCHGC06539 protein; n=1; Schistosoma j... 141 2e-32
UniRef50_A0CWR1 Cluster: Chromosome undetermined scaffold_3, who... 136 4e-31
UniRef50_P12695 Cluster: Dihydrolipoyllysine-residue acetyltrans... 134 3e-30
UniRef50_Q1EGH6 Cluster: Pyruvate dehydrogenase E2 subunit; n=1;... 130 3e-29
UniRef50_A7THD4 Cluster: Putative uncharacterized protein; n=1; ... 128 1e-28
UniRef50_O59816 Cluster: Dihydrolipoyllysine-residue acetyltrans... 126 8e-28
UniRef50_Q1EGH5 Cluster: Pyruvate dehydrogenase E2 subunit; n=3;... 124 3e-27
UniRef50_P20285 Cluster: Dihydrolipoyllysine-residue acetyltrans... 120 4e-26
UniRef50_Q8RWN9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 119 9e-26
UniRef50_Q0WQF7 Cluster: Dihydrolipoyllysine-residue acetyltrans... 117 3e-25
UniRef50_Q9SXV7 Cluster: Dihydrolipoamide acetyltransferase; n=1... 115 2e-24
UniRef50_A2WZU5 Cluster: Putative uncharacterized protein; n=2; ... 114 3e-24
UniRef50_A3BC27 Cluster: Putative uncharacterized protein; n=2; ... 113 4e-24
UniRef50_Q6PLQ2 Cluster: Dihydrolipoamide S-acetyltransferase; n... 112 1e-23
UniRef50_P36413 Cluster: Dihydrolipoyllysine-residue acetyltrans... 109 6e-23
UniRef50_A7SJI4 Cluster: Predicted protein; n=2; Nematostella ve... 105 2e-21
UniRef50_Q9R9N3 Cluster: Dihydrolipoyllysine-residue acetyltrans... 101 2e-20
UniRef50_A4RXN8 Cluster: Predicted protein; n=3; cellular organi... 100 8e-20
UniRef50_Q6KCM0 Cluster: Dihydrolipoyl transacetylase; n=1; Eugl... 99 1e-19
UniRef50_UPI0000ECB9E1 Cluster: Apoptosis inhibitor 5 (API-5).; ... 99 1e-19
UniRef50_Q6N5V4 Cluster: Pyruvate dehydrogenase E1 beta subunit;... 98 2e-19
UniRef50_UPI00015A4520 Cluster: UPI00015A4520 related cluster; n... 98 2e-19
UniRef50_Q68FJ5 Cluster: MGC86218 protein; n=3; Tetrapoda|Rep: M... 98 2e-19
UniRef50_A3WC78 Cluster: Pyruvate dehydrogenase E2 component; n=... 98 2e-19
UniRef50_O00330 Cluster: Pyruvate dehydrogenase protein X compon... 97 4e-19
UniRef50_Q4PHZ8 Cluster: Putative uncharacterized protein; n=1; ... 96 1e-18
UniRef50_Q92HK7 Cluster: Dihydrolipoyllysine-residue acetyltrans... 94 3e-18
UniRef50_Q73FZ4 Cluster: Pyruvate dehydrogenase complex, E2 comp... 94 4e-18
UniRef50_O66113 Cluster: Pyruvate dehydrogenase E1 component sub... 94 4e-18
UniRef50_Q5BXT9 Cluster: SJCHGC06137 protein; n=1; Schistosoma j... 93 5e-18
UniRef50_Q5KEE0 Cluster: Pyruvate dehydrogenase protein x compon... 93 5e-18
UniRef50_Q2H6F4 Cluster: Putative uncharacterized protein; n=3; ... 93 5e-18
UniRef50_UPI0000E4A22B Cluster: PREDICTED: similar to pyruvate d... 92 1e-17
UniRef50_UPI0000DB7177 Cluster: PREDICTED: similar to Pyruvate d... 92 1e-17
UniRef50_Q7RWS2 Cluster: Putative uncharacterized protein NCU000... 92 1e-17
UniRef50_Q2GCH9 Cluster: Pyruvate dehydrogenase complex, E2 comp... 91 2e-17
UniRef50_O66119 Cluster: Dihydrolipoyllysine-residue acetyltrans... 91 2e-17
UniRef50_O94709 Cluster: Probable pyruvate dehydrogenase protein... 91 4e-17
UniRef50_UPI0000509C9C Cluster: hypothetical protein LOC549074; ... 90 7e-17
UniRef50_A3UCP2 Cluster: Dihydrolipoamide acetyltransferase; n=1... 90 7e-17
UniRef50_Q5KIM3 Cluster: Dihydrolipoyllysine-residue acetyltrans... 89 9e-17
UniRef50_UPI0000383A75 Cluster: COG0508: Pyruvate/2-oxoglutarate... 88 2e-16
UniRef50_A4RM31 Cluster: Putative uncharacterized protein; n=1; ... 88 2e-16
UniRef50_Q2GI07 Cluster: Pyruvate dehydrogenase complex, E2 comp... 87 6e-16
UniRef50_Q6CNU8 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 86 8e-16
UniRef50_Q4DYI5 Cluster: Dihydrolipoamide acetyltransferase, put... 84 3e-15
UniRef50_Q1VYW1 Cluster: Dihydrolipoyllysine-residue acetyltrans... 83 8e-15
UniRef50_A7TK36 Cluster: Putative uncharacterized protein; n=1; ... 83 8e-15
UniRef50_P16451 Cluster: Pyruvate dehydrogenase complex protein ... 82 1e-14
UniRef50_Q6CF67 Cluster: Yarrowia lipolytica chromosome B of str... 82 2e-14
UniRef50_Q6FSM5 Cluster: Candida glabrata strain CBS138 chromoso... 81 2e-14
UniRef50_A7IFM6 Cluster: Biotin/lipoyl attachment domain-contain... 81 3e-14
UniRef50_A6DTS5 Cluster: Pyruvate dehydrogenase complex , E2 com... 80 5e-14
UniRef50_Q4QCG0 Cluster: Dihydrolipoamide acetyltransferaselike ... 80 5e-14
UniRef50_A6SFD7 Cluster: Putative uncharacterized protein; n=1; ... 80 7e-14
UniRef50_A3GI36 Cluster: Pyruvate dehydrogenase complex protein ... 79 9e-14
UniRef50_Q7NHG8 Cluster: Dihydrolipoamide S-acetyltransferase; n... 79 1e-13
UniRef50_Q47KD8 Cluster: Pyruvate dehydrogenase complex, E2 comp... 78 2e-13
UniRef50_A3VIE9 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 78 2e-13
UniRef50_Q9PKE7 Cluster: Pyruvate dehydrogenase, E2 component, d... 78 3e-13
UniRef50_Q8F4N2 Cluster: Dihydrolipoamide acetyltransferase comp... 78 3e-13
UniRef50_A0LSF1 Cluster: Catalytic domain of components of vario... 78 3e-13
UniRef50_Q7VDH5 Cluster: Dihydrolipoamide S-acetyltransferase; n... 77 5e-13
UniRef50_Q08V09 Cluster: Pyruvate dehydrogenase complex dihydrol... 77 5e-13
UniRef50_Q74Z83 Cluster: AGR323Cp; n=1; Eremothecium gossypii|Re... 77 7e-13
UniRef50_O84249 Cluster: Dihydrolipoamide Acetyltransferase; n=7... 76 9e-13
UniRef50_A0H5V3 Cluster: Dihydrolipoamide S-succinyltransferase;... 76 9e-13
UniRef50_Q4Q1F5 Cluster: Dihydrolipoamide acetyltransferase, put... 76 9e-13
UniRef50_UPI000150A9DD Cluster: pyruvate dehydrogenase complex d... 75 2e-12
UniRef50_Q8YDW4 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMP... 75 2e-12
UniRef50_A7Q7E8 Cluster: Chromosome chr18 scaffold_59, whole gen... 75 2e-12
UniRef50_Q2S152 Cluster: Dihydrolipoyllysine-residue acetyltrans... 75 2e-12
UniRef50_A6EAZ4 Cluster: Dihydrolipoyllysine-residue acetyltrans... 75 3e-12
UniRef50_Q7RFX9 Cluster: Putative dihydrolipoamide S-acetyltrans... 74 3e-12
UniRef50_Q38C09 Cluster: Dihydrolipoamide acetyltransferase, put... 74 3e-12
UniRef50_A1ZE93 Cluster: Pyruvate dehydrogenase complex dihydrol... 73 6e-12
UniRef50_UPI00015B5B2E Cluster: PREDICTED: similar to ENSANGP000... 73 1e-11
UniRef50_A0NRH6 Cluster: 2-oxo acid dehydrogenases acyltransfera... 72 1e-11
UniRef50_Q5IX02 Cluster: Plastid pyruvate dehydrogenase complex ... 72 2e-11
UniRef50_A3CFJ5 Cluster: Putative uncharacterized protein; n=2; ... 71 2e-11
UniRef50_Q3SL16 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 71 3e-11
UniRef50_P96104 Cluster: Dihydrolipoyl transacetylase and lipoam... 69 1e-10
UniRef50_Q8RD59 Cluster: Dihydrolipoamide acyltransferases; n=1;... 69 2e-10
UniRef50_Q9SQI8 Cluster: Dihydrolipoamide S-acetyltransferase; n... 69 2e-10
UniRef50_A1SYC2 Cluster: Dihydrolipoamide dehydrogenase E3 compo... 68 2e-10
UniRef50_A6Q3I4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 67 5e-10
UniRef50_Q48TW1 Cluster: Dihydrolipoamide acetyltransferase comp... 66 1e-09
UniRef50_Q97Y20 Cluster: Dihydrolipoamide S-acetyltransferase, a... 66 1e-09
UniRef50_A6Q9K5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 65 2e-09
UniRef50_Q5VGY2 Cluster: Dihydrolipoamide S-acetyltransferase; n... 65 2e-09
UniRef50_A4BP63 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 64 3e-09
UniRef50_Q1AZ52 Cluster: Catalytic domain of components of vario... 64 5e-09
UniRef50_A6X6G3 Cluster: Biotin/lipoyl attachment domain protein... 64 5e-09
UniRef50_A4AIF6 Cluster: Dihydrolipoamide acetyltransferase; n=1... 64 5e-09
UniRef50_Q74AE1 Cluster: Dehydrogenase complex E2 component, dih... 63 7e-09
UniRef50_A4M1P4 Cluster: Biotin/lipoyl attachment domain-contain... 63 7e-09
UniRef50_A0JS87 Cluster: Catalytic domain of components of vario... 63 7e-09
UniRef50_A6Q8W6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 63 9e-09
UniRef50_O31550 Cluster: Dihydrolipoyllysine-residue acetyltrans... 62 1e-08
UniRef50_Q1NYU2 Cluster: Dihydrolipoamide acyltransferase E2 com... 62 2e-08
UniRef50_A3SJ80 Cluster: Dihydrolipoamide acetyltransferase; n=1... 62 2e-08
UniRef50_A5KCF0 Cluster: Dihydrolipoamide acetyltransferase, put... 62 2e-08
UniRef50_Q8VPK7 Cluster: Dihydrolipoamide dehydrogenase; n=43; S... 61 3e-08
UniRef50_Q3CI28 Cluster: Biotin/lipoyl attachment:Catalytic doma... 61 3e-08
UniRef50_Q4Q822 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 60 5e-08
UniRef50_Q6AIE3 Cluster: Probable pyruvate dehydrogenase, E2 com... 60 6e-08
UniRef50_Q0LRZ3 Cluster: Dihydrolipoamide acetyltransferase, lon... 60 6e-08
UniRef50_Q8ZUR6 Cluster: Pyruvate dehydrogenase E2; n=1; Pyrobac... 60 6e-08
UniRef50_Q2S4D4 Cluster: 2-oxo acid dehydrogenases acyltransfera... 60 8e-08
UniRef50_Q59299 Cluster: Dihydrolipoyl dehydrogenase; n=6; Clost... 60 8e-08
UniRef50_A0K281 Cluster: Catalytic domain of components of vario... 59 1e-07
UniRef50_A6UDY3 Cluster: Biotin/lipoyl attachment domain-contain... 59 1e-07
UniRef50_A5MZI5 Cluster: PdhC; n=6; Clostridium|Rep: PdhC - Clos... 58 2e-07
UniRef50_A4FIZ9 Cluster: Acetoin dehydrogenase, dihydrolipoamide... 58 2e-07
UniRef50_A3VK82 Cluster: Putative uncharacterized protein; n=1; ... 58 2e-07
UniRef50_Q8RBW8 Cluster: Dihydrolipoamide acyltransferases; n=1;... 58 2e-07
UniRef50_A0Z5N6 Cluster: Pyruvate dehydrogenase complex, E2 comp... 58 2e-07
UniRef50_Q98FT5 Cluster: Dihydrolipoamide acetyltransferase homo... 58 3e-07
UniRef50_Q0LND0 Cluster: Dihydrolipoamide S-succinyltransferase;... 58 3e-07
UniRef50_A4WK39 Cluster: Catalytic domain of components of vario... 58 3e-07
UniRef50_Q4RLV1 Cluster: Chromosome 10 SCAF15019, whole genome s... 57 4e-07
UniRef50_A5UU13 Cluster: Dihydrolipoyllysine-residue succinyltra... 57 6e-07
UniRef50_Q553V8 Cluster: Dihydrolipoamide S-succinyltransferase;... 57 6e-07
UniRef50_Q65MC9 Cluster: AcoC; n=1; Bacillus licheniformis ATCC ... 56 7e-07
UniRef50_A7BC27 Cluster: Putative uncharacterized protein; n=1; ... 56 1e-06
UniRef50_A4XEQ9 Cluster: Catalytic domain of components of vario... 56 1e-06
UniRef50_Q6FDE9 Cluster: Dihydrolipoamide acetyltransferase; n=3... 56 1e-06
UniRef50_Q39FN4 Cluster: Alpha/beta hydrolase; n=10; Burkholderi... 56 1e-06
UniRef50_UPI00006DB259 Cluster: COG0508: Pyruvate/2-oxoglutarate... 55 2e-06
UniRef50_UPI00006A2AB5 Cluster: UPI00006A2AB5 related cluster; n... 55 2e-06
UniRef50_Q54TR7 Cluster: Dihydrolipoyl transacylase; n=1; Dictyo... 55 2e-06
UniRef50_Q0W153 Cluster: Pyruvate dehydrogenase complex E2, dihy... 55 2e-06
UniRef50_UPI00015552BA Cluster: PREDICTED: similar to dihydrolip... 55 2e-06
UniRef50_Q18CC1 Cluster: E3 component of acetoin dehydrogenase e... 55 2e-06
UniRef50_P36957 Cluster: Dihydrolipoyllysine-residue succinyltra... 55 2e-06
UniRef50_Q89AJ6 Cluster: Dihydrolipoyllysine-residue succinyltra... 55 2e-06
UniRef50_Q1M9D5 Cluster: Putative biotin-binding protein; n=1; R... 54 3e-06
UniRef50_Q088Y5 Cluster: Biotin/lipoyl attachment domain-contain... 54 3e-06
UniRef50_Q97CK2 Cluster: Pyruvate dehydrogenase E2 / dihydrolipo... 54 3e-06
UniRef50_Q4UKI7 Cluster: Dihydrolipoyllysine-residue succinyltra... 54 3e-06
UniRef50_A6GG26 Cluster: Dihydrolipoyllysine-residue acetyltrans... 54 4e-06
UniRef50_Q7WED2 Cluster: Probable 2-oxo acid dehydrogenases acyl... 54 5e-06
UniRef50_A5CEI9 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 54 5e-06
UniRef50_Q82SG4 Cluster: SucB; dihydrolipoamide succinyltransfer... 53 7e-06
UniRef50_Q12FH2 Cluster: Catalytic domain of components of vario... 53 7e-06
UniRef50_A4XHV3 Cluster: Catalytic domain of components of vario... 53 7e-06
UniRef50_A1WK19 Cluster: Alpha/beta hydrolase fold; n=1; Vermine... 53 7e-06
UniRef50_A0Z3Y6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 53 7e-06
UniRef50_Q4UGK1 Cluster: Dihydrolipoamide succinyltransferase co... 53 7e-06
UniRef50_Q59695 Cluster: Dihydrolipoyllysine-residue acetyltrans... 53 7e-06
UniRef50_Q9KES1 Cluster: Dihydrolipoamide S-acetyltransferase; n... 53 9e-06
UniRef50_A4A156 Cluster: Pyruvate dehydrogenase, E2 component, d... 52 1e-05
UniRef50_A1UIB1 Cluster: Catalytic domain of components of vario... 52 2e-05
UniRef50_A0G901 Cluster: Biotin/lipoyl attachment; n=1; Burkhold... 52 2e-05
UniRef50_P65634 Cluster: Dihydrolipoyllysine-residue succinyltra... 52 2e-05
UniRef50_P16263 Cluster: Dihydrolipoyllysine-residue succinyltra... 52 2e-05
UniRef50_Q63TQ8 Cluster: Dihydrolipoamide succinyltransferase co... 52 2e-05
UniRef50_Q3SEX1 Cluster: Dihydrolipoamide succinyltransferase; n... 52 2e-05
UniRef50_A0LP66 Cluster: 2-oxoglutarate dehydrogenase, E2 subuni... 52 2e-05
UniRef50_A0H074 Cluster: E3 binding; n=2; Chloroflexus|Rep: E3 b... 52 2e-05
UniRef50_A0G738 Cluster: Catalytic domain of components of vario... 51 3e-05
UniRef50_Q4AFC2 Cluster: Biotin/lipoyl attachment; n=1; Chlorobi... 51 4e-05
UniRef50_Q1AT73 Cluster: Catalytic domain of components of vario... 51 4e-05
UniRef50_Q0A5F2 Cluster: Catalytic domain of components of vario... 51 4e-05
UniRef50_Q5HKM0 Cluster: Acetoin dehydrogenase, E2 component, di... 50 5e-05
UniRef50_O32959 Cluster: Dihydrolipoamide succinyltransferase; n... 50 5e-05
UniRef50_Q49XM4 Cluster: Dihydrolipoyllysine-residue succinyltra... 50 5e-05
UniRef50_Q5FS04 Cluster: Dihydrolipoamide succinyl transferase (... 50 9e-05
UniRef50_Q39RZ0 Cluster: Dihydrolipoamide succinyltransferase; n... 50 9e-05
UniRef50_A3CMZ5 Cluster: Dihydrolipoamide acetyl transferase, E2... 50 9e-05
UniRef50_A1UBW5 Cluster: Catalytic domain of components of vario... 50 9e-05
UniRef50_Q5UYG4 Cluster: Dihydrolipoamide acetyltransferase comp... 50 9e-05
UniRef50_A5UTW4 Cluster: Catalytic domain of components of vario... 49 1e-04
UniRef50_A0LAA3 Cluster: 2-oxoglutarate dehydrogenase, E2 subuni... 49 1e-04
UniRef50_Q5BY55 Cluster: SJCHGC04170 protein; n=1; Schistosoma j... 49 1e-04
UniRef50_Q234F3 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 49 1e-04
UniRef50_Q6L1M0 Cluster: Dihydrolipoamide acetyltransferase comp... 49 1e-04
UniRef50_Q5L233 Cluster: Pyruvate dehydrogenase E2; n=2; Geobaci... 49 1e-04
UniRef50_Q7X2B2 Cluster: PdhC; n=1; Lactobacillus reuteri|Rep: P... 49 1e-04
UniRef50_A2TU26 Cluster: Lipoamide acyltransferase component of ... 49 1e-04
UniRef50_A0H458 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 49 1e-04
UniRef50_Q6MPR6 Cluster: Pyruvate dehydrogenase E2; n=1; Bdellov... 48 2e-04
UniRef50_A6PBA2 Cluster: Catalytic domain of components of vario... 48 2e-04
UniRef50_A6C4P4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 48 2e-04
UniRef50_A1T0M1 Cluster: Pyruvate dehydrogenase complex, E2 comp... 48 2e-04
UniRef50_A1SJ23 Cluster: Catalytic domain of components of vario... 48 2e-04
UniRef50_Q9FC63 Cluster: Putative acyltransferase; n=1; Streptom... 48 3e-04
UniRef50_A5V4B2 Cluster: Catalytic domain of components of vario... 48 3e-04
UniRef50_Q3A0D1 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 48 3e-04
UniRef50_Q59658 Cluster: Dihydrolipoamide acetyltransferase; n=3... 48 3e-04
UniRef50_Q1QQR6 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 48 3e-04
UniRef50_A0LQU7 Cluster: Catalytic domain of components of vario... 48 3e-04
UniRef50_Q9FLQ4 Cluster: 2-oxoglutarate dehydrogenase E2 subunit... 48 3e-04
UniRef50_Q0E0X4 Cluster: Os02g0514700 protein; n=2; Oryza sativa... 48 3e-04
UniRef50_Q7ULX6 Cluster: Dihydrolipoamide succinyltransferase co... 47 5e-04
UniRef50_Q1GTH9 Cluster: Catalytic domain of components of vario... 47 5e-04
UniRef50_Q0RVL0 Cluster: Dihydrolipoyllysine-residue succinyltra... 47 5e-04
UniRef50_A0XBY6 Cluster: Biotin/lipoyl attachment domain-contain... 47 5e-04
UniRef50_A6WD54 Cluster: 2-oxoglutarate dehydrogenase E2 compone... 47 6e-04
UniRef50_A1ZHD0 Cluster: Dihydrolipoyllysine-residue succinyltra... 47 6e-04
UniRef50_Q5UWH1 Cluster: Dihydrolipoamide S-acetyltransferase co... 47 6e-04
UniRef50_Q92BY1 Cluster: Lin1411 protein; n=15; Bacillales|Rep: ... 46 8e-04
UniRef50_Q7NB00 Cluster: AceF; n=1; Mycoplasma gallisepticum|Rep... 46 8e-04
UniRef50_Q6A613 Cluster: Dihydrolipoamide acetyltransferase comp... 46 8e-04
UniRef50_Q2J8A0 Cluster: Dehydrogenase subunit; n=9; Actinobacte... 46 8e-04
UniRef50_A6TMP1 Cluster: Catalytic domain of components of vario... 46 8e-04
UniRef50_A5V555 Cluster: Biotin/lipoyl attachment domain-contain... 46 8e-04
UniRef50_A5EW59 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 46 8e-04
UniRef50_Q5KP05 Cluster: Tricarboxylic acid cycle-related protei... 46 8e-04
UniRef50_Q5WE92 Cluster: Acetoin dehydrogenase E2 component; n=1... 46 0.001
UniRef50_A3U7C0 Cluster: Lipoamide acyltransferase component of ... 46 0.001
UniRef50_P21883 Cluster: Dihydrolipoyllysine-residue acetyltrans... 46 0.001
UniRef50_Q9RYB8 Cluster: 2-oxo acid dehydrogenase, E2 component;... 46 0.001
UniRef50_Q9KG97 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillu... 46 0.001
UniRef50_Q4L6L6 Cluster: Branched-chain alpha-keto acid dehydrog... 46 0.001
UniRef50_Q1YS54 Cluster: Dihydrolipoamide acetyltransferase; n=1... 45 0.002
UniRef50_A7AT28 Cluster: Lipoamide acyltransferase component of ... 45 0.002
UniRef50_P27747 Cluster: Dihydrolipoyllysine-residue acetyltrans... 45 0.002
UniRef50_Q9X6X2 Cluster: Lipoamide acyltransferase; n=3; Cystoba... 45 0.002
UniRef50_Q057P2 Cluster: 2-oxoglutarate dehydrogenase E2 compone... 45 0.002
UniRef50_P0AFG7 Cluster: Dihydrolipoyllysine-residue succinyltra... 45 0.002
UniRef50_Q8DFQ0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 44 0.003
UniRef50_Q0SGE5 Cluster: Dihydrolipoyllysine-residue succinyltra... 44 0.003
UniRef50_A5V538 Cluster: Catalytic domain of components of vario... 44 0.003
UniRef50_Q9RXQ3 Cluster: Pyruvate dehydrogenase complex, dihydro... 44 0.004
UniRef50_A3HTS0 Cluster: 2-oxo acid dehydrogenases acyltransfera... 44 0.004
UniRef50_Q9VXY3 Cluster: CG5599-PA; n=4; Diptera|Rep: CG5599-PA ... 44 0.004
UniRef50_Q9I1M0 Cluster: Lipoamide acyltransferase component of ... 44 0.004
UniRef50_Q98ED1 Cluster: Dihydrolipoamide succinyl transferase; ... 44 0.006
UniRef50_A3UGB6 Cluster: Dihydrolipoamide acetyltransferase; n=2... 44 0.006
UniRef50_A0LLM2 Cluster: Catalytic domain of components of vario... 44 0.006
UniRef50_A7AMV7 Cluster: Biotin-requiring enzyme family protein;... 44 0.006
UniRef50_Q9HN75 Cluster: Dihydrolipoamide S-acetyltransferase; n... 44 0.006
UniRef50_P57389 Cluster: Dihydrolipoyllysine-residue succinyltra... 44 0.006
UniRef50_Q67SE5 Cluster: Pyruvate dehydrogenase E2; n=1; Symbiob... 43 0.007
UniRef50_A1FTV4 Cluster: Catalytic domain of components of vario... 43 0.007
UniRef50_Q6ABX9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 43 0.007
UniRef50_P35489 Cluster: Dihydrolipoyllysine-residue acetyltrans... 43 0.007
UniRef50_P19262 Cluster: Dihydrolipoyllysine-residue succinyltra... 43 0.007
UniRef50_UPI0001555D03 Cluster: PREDICTED: similar to 2-oxogluta... 43 0.010
UniRef50_Q1IMV8 Cluster: Dihydrolipoamide acetyltransferase; n=1... 43 0.010
UniRef50_Q7RIU5 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 43 0.010
UniRef50_Q6KH64 Cluster: Pyruvate dehydrogenase E3 component dih... 42 0.013
UniRef50_Q5Z123 Cluster: Putative branched-chain alpha-keto acid... 42 0.013
UniRef50_Q5KUY3 Cluster: Pyruvate dehydrogenase E2; n=2; Geobaci... 42 0.013
UniRef50_Q3JBP0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 42 0.013
UniRef50_Q1IIF0 Cluster: Dihydrolipoamide S-succinyltransferase;... 42 0.013
UniRef50_Q58628 Cluster: Pyruvate carboxylase subunit B; n=8; ce... 42 0.013
UniRef50_A6UGY8 Cluster: Dihydrolipoyllysine-residue succinyltra... 42 0.017
UniRef50_Q6FYD4 Cluster: Dihydrolipoyllysine-residue succinyltra... 42 0.017
UniRef50_Q1Q664 Cluster: Similar to 2-oxoglutarate dehydrogenase... 42 0.023
UniRef50_Q0SJA7 Cluster: Dihydrolipoyllysine-residue succinyltra... 42 0.023
UniRef50_A6W003 Cluster: Catalytic domain of components of vario... 42 0.023
UniRef50_A4BTC4 Cluster: Dihydrolipoamide acetyltransferase; n=2... 42 0.023
UniRef50_Q4P9L5 Cluster: Putative uncharacterized protein; n=1; ... 42 0.023
UniRef50_Q4JC02 Cluster: Conserved protein; n=4; Sulfolobaceae|R... 42 0.023
UniRef50_UPI0000D56122 Cluster: PREDICTED: similar to Lipoamide ... 41 0.030
UniRef50_Q892P7 Cluster: Dihydrolipoamide dehydrogenase; n=3; Cl... 41 0.030
UniRef50_A6GB59 Cluster: Alpha keto acid dehydrogenase complex, ... 41 0.030
UniRef50_Q7MB23 Cluster: Similar to peptide synthetase. Putative... 41 0.040
UniRef50_Q5EIH5 Cluster: Dihydrolipoamide succinyltransferase co... 41 0.040
UniRef50_Q3VZH8 Cluster: Biotin/lipoyl attachment:Catalytic doma... 41 0.040
UniRef50_A0TVZ3 Cluster: Biotin/lipoyl attachment; n=1; Burkhold... 41 0.040
UniRef50_Q6C806 Cluster: Similar to tr|Q9VXY3 Drosophila melanog... 41 0.040
UniRef50_A6SDP7 Cluster: Putative uncharacterized protein; n=1; ... 41 0.040
UniRef50_Q83G30 Cluster: Dihydrolipoamide succinyltransferase co... 40 0.052
UniRef50_Q6KH63 Cluster: Pyruvate dehydrogenase E2 component dih... 40 0.052
UniRef50_Q1PVI6 Cluster: Putative uncharacterized protein; n=1; ... 40 0.052
UniRef50_Q97VY7 Cluster: Biotin carboxyl carrier protein of prop... 40 0.052
UniRef50_Q9PJZ6 Cluster: 2-oxo acid dehydrogenase, E2 component,... 40 0.069
UniRef50_Q2BFQ8 Cluster: Hexapeptide transferase family protein;... 40 0.069
UniRef50_A1SQB9 Cluster: Catalytic domain of components of vario... 40 0.069
UniRef50_A0M206 Cluster: Dihydrolipoyllysine-residue acetyltrans... 40 0.069
UniRef50_O27179 Cluster: Pyruvate carboxylase subunit B; n=18; E... 40 0.069
UniRef50_Q98PG2 Cluster: DIHYDROLIPOAMIDE DEHYDROGENASE; n=8; My... 40 0.092
UniRef50_Q8EVQ0 Cluster: Dihydrolipoamide acetyltransferase of p... 40 0.092
UniRef50_O66382 Cluster: Esterase2; n=2; Acetobacteraceae|Rep: E... 40 0.092
UniRef50_A4F1Y4 Cluster: Dihydrolopoamide acyltransferase; n=1; ... 40 0.092
UniRef50_UPI00006D8691 Cluster: COG0508: Pyruvate/2-oxoglutarate... 39 0.12
UniRef50_Q8CX89 Cluster: Pyruvate dehydrogenase E2; n=4; Bacilla... 39 0.12
UniRef50_Q67ME8 Cluster: Branched-chain alpha-keto acid dehydrog... 39 0.12
UniRef50_A3WJV9 Cluster: Apha keto acid dehydrogenase complex, E... 39 0.12
UniRef50_Q5VVL7 Cluster: Dihydrolipoamide branched chain transac... 39 0.12
UniRef50_P11182 Cluster: Lipoamide acyltransferase component of ... 39 0.12
UniRef50_P37942 Cluster: Lipoamide acyltransferase component of ... 39 0.12
UniRef50_UPI000155CECB Cluster: PREDICTED: similar to transacyla... 39 0.16
UniRef50_Q8PQ85 Cluster: Dihydrolipoamide acyltransferase; n=7; ... 39 0.16
UniRef50_A6DL93 Cluster: Dihydrolipoamide acetyltransferase; n=1... 39 0.16
UniRef50_Q57Z16 Cluster: Dihydrolipoamide branched chain transac... 39 0.16
UniRef50_Q5ZV80 Cluster: Dihydrolipoamide acetyltransferase; n=5... 38 0.21
UniRef50_Q4FS31 Cluster: Dihydrolipoyllysine acetyltransferase c... 38 0.21
UniRef50_Q8U4T3 Cluster: 2-oxo acid dehydrogenase lipoyl domain;... 38 0.21
UniRef50_P22439 Cluster: Pyruvate dehydrogenase protein X compon... 38 0.21
UniRef50_Q8RAJ2 Cluster: Biotin carboxyl carrier protein; n=4; T... 38 0.28
UniRef50_Q7NLM9 Cluster: Gll1092 protein; n=1; Gloeobacter viola... 38 0.28
UniRef50_Q749T6 Cluster: Pyruvate dehydrogenase complex E2 compo... 38 0.28
UniRef50_A0YCP9 Cluster: Pyruvate dehydrogenase complex dihydrol... 38 0.28
UniRef50_Q9M724 Cluster: Branched chain alpha-keto acid dehydrog... 38 0.28
UniRef50_Q4QJI5 Cluster: Dihydrolipoamide branched chain transac... 38 0.28
UniRef50_P06959 Cluster: Dihydrolipoyllysine-residue acetyltrans... 38 0.28
UniRef50_P09062 Cluster: Lipoamide acyltransferase component of ... 38 0.28
UniRef50_Q21RD8 Cluster: Biotin/lipoyl attachment; n=1; Rhodofer... 38 0.37
UniRef50_A3JES0 Cluster: 2-oxoglutarate dehydrogenase E2; n=1; M... 38 0.37
UniRef50_A1IDW2 Cluster: Oxaloacetate decarboxylase alpha subuni... 38 0.37
UniRef50_A0JUQ7 Cluster: Catalytic domain of components of vario... 38 0.37
UniRef50_Q4N034 Cluster: Putative uncharacterized protein; n=1; ... 38 0.37
UniRef50_Q2UJZ9 Cluster: Dihydrolipoamide transacylase; n=9; Eur... 38 0.37
UniRef50_Q2UDD6 Cluster: Predicted protein; n=1; Aspergillus ory... 38 0.37
UniRef50_Q1E5N3 Cluster: Dihydrolipoyllysine-residue succinyltra... 38 0.37
UniRef50_Q9YBC6 Cluster: Pyruvate dehydrogenase complex, E2 comp... 38 0.37
UniRef50_Q9Y9E0 Cluster: Putative uncharacterized protein; n=1; ... 38 0.37
UniRef50_Q8F3R1 Cluster: Biotin_lipoyl domain protein; n=4; Lept... 37 0.49
UniRef50_Q2JA39 Cluster: Dehydrogenase subunit; n=4; Actinomycet... 37 0.49
UniRef50_A6EP31 Cluster: Putative uncharacterized protein; n=1; ... 37 0.49
UniRef50_A4XMC5 Cluster: Biotin/lipoyl attachment domain-contain... 37 0.49
UniRef50_A3U9Z3 Cluster: Biotin carboxyl carrier protein; n=1; C... 37 0.49
UniRef50_Q4U9K9 Cluster: 2-oxoglutarate dehydrogenase complex su... 37 0.49
UniRef50_A7AQM6 Cluster: Dihydrolipoamide succinyltransferase, p... 37 0.49
UniRef50_Q5KKT5 Cluster: Methylcrotonoyl-Coenzyme A carboxylase ... 37 0.49
UniRef50_O94681 Cluster: Probable dihydrolipoyllysine-residue su... 37 0.49
UniRef50_Q9ZAA7 Cluster: Glutaconyl-CoA decarboxylase subunit ga... 37 0.49
UniRef50_Q8FRQ0 Cluster: Pyruvate carboxylase; n=47; Bacteria|Re... 37 0.65
UniRef50_Q8EJN8 Cluster: Pyruvate dehydrogenase complex, E2 comp... 37 0.65
UniRef50_Q2B858 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillu... 36 0.85
UniRef50_A4CQ51 Cluster: Lipoamide acyltransferase component of ... 36 0.85
UniRef50_A0M5Y1 Cluster: Dihydrolipoyllysine-residue succinyltra... 36 0.85
UniRef50_A7DR94 Cluster: Biotin/lipoyl attachment domain-contain... 36 0.85
UniRef50_Q8D6Q5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 36 1.1
UniRef50_Q3WAF9 Cluster: Biotin/lipoyl attachment:Catalytic doma... 36 1.1
UniRef50_A6PJ30 Cluster: Catalytic domain of components of vario... 36 1.1
UniRef50_A4RMY6 Cluster: Putative uncharacterized protein; n=1; ... 36 1.1
UniRef50_Q59638 Cluster: Dihydrolipoyllysine-residue acetyltrans... 36 1.1
UniRef50_Q820A3 Cluster: AceF; dihydrolipoamide acetyltransferas... 36 1.5
UniRef50_A6FIQ1 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 36 1.5
UniRef50_A0PU60 Cluster: Dihydrolipoamide S-acetyltransferase E2... 36 1.5
UniRef50_A0JY25 Cluster: Biotin/lipoyl attachment domain-contain... 36 1.5
UniRef50_A3DPF7 Cluster: Biotin/lipoyl attachment domain-contain... 36 1.5
UniRef50_UPI0000DB75B7 Cluster: PREDICTED: similar to Lipoamide ... 35 2.0
UniRef50_Q0VRX7 Cluster: Pyruvate dehydrogenase, E2 component; n... 35 2.0
UniRef50_A1VJQ9 Cluster: Efflux transporter, RND family, MFP sub... 35 2.0
UniRef50_A1SQ65 Cluster: Catalytic domain of components of vario... 35 2.0
UniRef50_A1RJV4 Cluster: Catalytic domain of components of vario... 35 2.0
UniRef50_Q4JBV5 Cluster: Conserved protein; n=2; Sulfolobus|Rep:... 35 2.0
UniRef50_Q9RPS3 Cluster: Dihydrolipoamide acyltransferase; n=3; ... 35 2.6
UniRef50_A5V417 Cluster: Biotin/lipoyl attachment domain-contain... 35 2.6
UniRef50_A5CVP1 Cluster: Pyruvate dehydrogenase complex E2 compo... 35 2.6
UniRef50_Q23DL9 Cluster: TBC domain containing protein; n=1; Tet... 35 2.6
UniRef50_O28067 Cluster: Methylmalonyl-CoA decarboxylase, biotin... 35 2.6
UniRef50_UPI0000E48C7F Cluster: PREDICTED: similar to transacyla... 34 3.4
UniRef50_Q8XJF2 Cluster: Pyrimidine-nucleoside phosphorylase; n=... 34 3.4
UniRef50_Q6F713 Cluster: Dihydrolipoamide S-acetyltransferase, E... 34 3.4
UniRef50_Q5P915 Cluster: Pyruvate dehydrogenase multienzyme comp... 34 3.4
UniRef50_Q2JGZ2 Cluster: Dehydrogenase subunit; n=1; Frankia sp.... 34 3.4
UniRef50_A4AGT3 Cluster: Putative dihydrolipoamide acyltransfera... 34 3.4
UniRef50_A1ZWM2 Cluster: Bacterial transferase family protein; n... 34 3.4
UniRef50_Q2H5B2 Cluster: Putative uncharacterized protein; n=2; ... 34 3.4
UniRef50_A6RRC1 Cluster: Putative uncharacterized protein; n=2; ... 34 3.4
UniRef50_Q8KG12 Cluster: Acetyl-CoA carboxylase, biotin carboxyl... 34 4.6
UniRef50_Q2RYP2 Cluster: Membrane fusion efflux protein, putativ... 34 4.6
UniRef50_A3UET4 Cluster: 3-methylcrotonyl-CoA carboxylase alpha ... 34 4.6
UniRef50_A2VX19 Cluster: Pyruvate dehydrogenase complex, dehydro... 34 4.6
UniRef50_A1RMQ5 Cluster: Oxaloacetate decarboxylase alpha subuni... 34 4.6
UniRef50_Q7RS62 Cluster: Plasmodium vivax PV1H14105_P; n=8; Plas... 34 4.6
UniRef50_A2QTP2 Cluster: Catalytic activity: Acetyl-CoA + L-homo... 34 4.6
UniRef50_Q13GQ6 Cluster: Dihydrolipoamide acyltransferase (E2) c... 33 6.0
UniRef50_Q03P62 Cluster: Glycine cleavage system H protein; n=1;... 33 6.0
UniRef50_A4CPZ2 Cluster: Pyruvate carboxylase; n=1; Robiginitale... 33 6.0
UniRef50_A0Q4T8 Cluster: Peptidyl-prolyl cis-trans isomerase; n=... 33 6.0
UniRef50_Q7RNW8 Cluster: Acetyl-CoA carboxylase 1-related; n=11;... 33 6.0
UniRef50_A5K361 Cluster: Biotin carboxylase subunit of acetyl Co... 33 6.0
UniRef50_Q7SH25 Cluster: Putative uncharacterized protein NCU027... 33 6.0
UniRef50_Q0UN70 Cluster: Putative uncharacterized protein; n=1; ... 33 6.0
UniRef50_P45118 Cluster: Dihydrolipoyllysine-residue acetyltrans... 33 6.0
UniRef50_Q15U82 Cluster: Catalytic domain of components of vario... 33 8.0
UniRef50_Q0BY83 Cluster: Glyoxalase family protein; n=4; Bacteri... 33 8.0
UniRef50_A7C6V0 Cluster: Acetyl-CoA carboxylase, biotin carboxyl... 33 8.0
UniRef50_A3VT82 Cluster: Biotin carboxyl carrier protein subunit... 33 8.0
UniRef50_A1R9E2 Cluster: Pyruvate dehydrogenase E2; n=2; Actinom... 33 8.0
UniRef50_Q5V5W4 Cluster: Carbamoyl phosphate synthase L chain; n... 33 8.0
>UniRef50_Q19749 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=6; Bilateria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex, mitochondrial
precursor - Caenorhabditis elegans
Length = 507
Score = 176 bits (428), Expect = 6e-43
Identities = 84/116 (72%), Positives = 98/116 (84%), Gaps = 2/116 (1%)
Frame = +3
Query: 246 QMRYYSS--LPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFE 419
Q+R YSS LP H +V LPALSPTME G++VSW+KKEGD+LSEGDLLCEIETDKATMGFE
Sbjct: 65 QVRLYSSGNLPKHNRVALPALSPTMELGTVVSWQKKEGDQLSEGDLLCEIETDKATMGFE 124
Query: 420 TPEEGYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQ 587
TPEEGYLAKILI G+K VP+GKLLCIIV ++ DVAAFKDFKDD + + PA++
Sbjct: 125 TPEEGYLAKILIQEGSKDVPIGKLLCIIVDNEADVAAFKDFKDDGASSGGSAPAAE 180
>UniRef50_P10515 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=46; cellular
organisms|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor - Homo sapiens (Human)
Length = 614
Score = 143 bits (346), Expect = 5e-33
Identities = 67/108 (62%), Positives = 86/108 (79%), Gaps = 1/108 (0%)
Frame = +3
Query: 252 RYYSSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEE 431
RYYS LP H KV LP+LSPTM++G+I WEKKEGDK++EGDL+ E+ETDKAT+GFE+ EE
Sbjct: 51 RYYS-LPPHQKVPLPSLSPTMQAGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEE 109
Query: 432 GYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPA-TPQ 572
Y+AKIL+ GT+ VP+G ++CI VG D+ AFK++ DSS A TPQ
Sbjct: 110 CYMAKILVAEGTRDVPIGAIICITVGKPEDIEAFKNYTLDSSAAPTPQ 157
Score = 136 bits (329), Expect = 6e-31
Identities = 65/107 (60%), Positives = 81/107 (75%), Gaps = 1/107 (0%)
Frame = +3
Query: 261 SSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYL 440
SS P H++V LPALSPTM G++ WEKK G+KLSEGDLL EIETDKAT+GFE EEGYL
Sbjct: 180 SSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYL 239
Query: 441 AKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFK-DDSSPATPQKP 578
AKIL+P GT+ VP+G LCIIV + D++AF D++ + + PQ P
Sbjct: 240 AKILVPEGTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQVP 286
>UniRef50_Q5DAY9 Cluster: SJCHGC06539 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06539 protein - Schistosoma
japonicum (Blood fluke)
Length = 247
Score = 141 bits (342), Expect = 2e-32
Identities = 67/107 (62%), Positives = 83/107 (77%), Gaps = 2/107 (1%)
Frame = +3
Query: 258 YSSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGY 437
+ S P+H+ V LP LSPTME+G++VSW K EGD++SEGDLL EIETDKATM F+ E GY
Sbjct: 59 FLSYPTHLVVKLPNLSPTMETGTVVSWAKNEGDEVSEGDLLAEIETDKATMSFDASESGY 118
Query: 438 LAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSP--ATPQ 572
LAKIL PAG+K +PVG LCIIV D+N V AFKD+ +S+ ATP+
Sbjct: 119 LAKILAPAGSKDIPVGTALCIIVQDENAVPAFKDYVVESTEKVATPE 165
>UniRef50_A0CWR1 Cluster: Chromosome undetermined scaffold_3, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_3,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 628
Score = 136 bits (330), Expect = 4e-31
Identities = 70/138 (50%), Positives = 101/138 (73%), Gaps = 5/138 (3%)
Frame = +3
Query: 189 KLLEHAQNQTV-LSTPQWT-VQMRYYSS-LPSHIKVNLPALSPTMESGSIVSWEKKEGDK 359
KLL QT+ + P +T + + Y+S+ LP H K+ +PALSPTME+G+I + KK GD
Sbjct: 15 KLLHCVPLQTLSIRGPLFTSIPVSYFSTTLPKHKKLEMPALSPTMETGNIQKYLKKVGDP 74
Query: 360 LSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKD 539
++ GD+LCE+ETDKAT+GFE +EG+LA+IL+P G+KGV VG+L+ +IV Q+DVA+F +
Sbjct: 75 ITAGDVLCEVETDKATVGFEMQDEGFLAQILVPEGSKGVKVGQLVAVIVPKQSDVASFAN 134
Query: 540 FKDDSSP--ATPQKPASQ 587
+KD SS + KPA+Q
Sbjct: 135 YKDSSSQQCSAASKPAAQ 152
Score = 122 bits (295), Expect = 8e-27
Identities = 54/121 (44%), Positives = 82/121 (67%)
Frame = +3
Query: 225 STPQWTVQMRYYSSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKA 404
STPQ + P H K+ LPALSPTME G+++ W KEGD++S GD++CEIETDKA
Sbjct: 157 STPQRAQPAATGGAFPKHSKLGLPALSPTMEKGNLMKWLVKEGDRISPGDVICEIETDKA 216
Query: 405 TMGFETPEEGYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPAS 584
T+GFE E+GY+AK+++PAG+K + +G +L I +++V +F ++ + + A Q +
Sbjct: 217 TVGFEVQEDGYIAKLMVPAGSKDIKLGTILAISTPKKDNVPSFTNYTLEGAAAAAQTTQA 276
Query: 585 Q 587
Q
Sbjct: 277 Q 277
>UniRef50_P12695 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=3;
Saccharomycetales|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 482
Score = 134 bits (323), Expect = 3e-30
Identities = 63/118 (53%), Positives = 83/118 (70%), Gaps = 5/118 (4%)
Frame = +3
Query: 243 VQMRYYSSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFET 422
+Q+R Y+S P H + +PALSPTM G++ +W KKEGD+LS G+++ EIETDKA M FE
Sbjct: 23 LQLRCYASYPEHTIIGMPALSPTMTQGNLAAWTKKEGDQLSPGEVIAEIETDKAQMDFEF 82
Query: 423 PEEGYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFK-----DDSSPATPQKPA 581
E+GYLAKIL+P GTK +PV K + + V D+ DV AFKDFK DS +T +PA
Sbjct: 83 QEDGYLAKILVPEGTKDIPVNKPIAVYVEDKADVPAFKDFKLEDSGSDSKTSTKAQPA 140
>UniRef50_Q1EGH6 Cluster: Pyruvate dehydrogenase E2 subunit; n=1;
Euplotes sp. BB-2004|Rep: Pyruvate dehydrogenase E2
subunit - Euplotes sp. BB-2004
Length = 459
Score = 130 bits (315), Expect = 3e-29
Identities = 54/116 (46%), Positives = 84/116 (72%)
Frame = +3
Query: 240 TVQMRYYSSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFE 419
++ R++S LP H+K+ +P+LSPTME G++ W KK GD++ GD+L E+ETDKAT+ FE
Sbjct: 28 SLPFRFFSDLPPHVKLQMPSLSPTMEKGNLAKWCKKVGDQVEPGDILAEVETDKATVDFE 87
Query: 420 TPEEGYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQ 587
E+GY+AK+L+ G + + +G+L+ I V D++DVAAFKD+K +S+ Q P +
Sbjct: 88 MQEDGYVAKLLVEEGAQDIALGELVAISVEDEDDVAAFKDYKPESTSEASQAPVKE 143
>UniRef50_A7THD4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 484
Score = 128 bits (310), Expect = 1e-28
Identities = 59/99 (59%), Positives = 75/99 (75%)
Frame = +3
Query: 249 MRYYSSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPE 428
+R YSS PS+ +N+PALSPTM G++ SW KKEG++LS GD++ E+ETDKATM FE +
Sbjct: 17 LRLYSSYPSYSIINMPALSPTMTHGNLASWTKKEGEQLSVGDVIAEVETDKATMDFEFQD 76
Query: 429 EGYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFK 545
+GYLAKIL+ G K VPV K + I V D+ DV AFKDFK
Sbjct: 77 DGYLAKILVNQGAKDVPVNKPIAIYVEDEADVQAFKDFK 115
>UniRef50_O59816 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=1;
Schizosaccharomyces pombe|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex, mitochondrial
precursor - Schizosaccharomyces pombe (Fission yeast)
Length = 483
Score = 126 bits (303), Expect = 8e-28
Identities = 60/109 (55%), Positives = 79/109 (72%), Gaps = 1/109 (0%)
Frame = +3
Query: 270 PSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKI 449
P+H +N+PALSPTM +G+I +++KK GDK+ GD+LCEIETDKA + FE +EGYLAKI
Sbjct: 51 PAHTVINMPALSPTMTTGNIGAFQKKIGDKIEPGDVLCEIETDKAQIDFEQQDEGYLAKI 110
Query: 450 LIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFK-DDSSPATPQKPASQDK 593
LI GTK VPVGK L + V ++ DVAA DF +DSS P + ++K
Sbjct: 111 LIETGTKDVPVGKPLAVTVENEGDVAAMADFTIEDSSAKEPSAKSGEEK 159
>UniRef50_Q1EGH5 Cluster: Pyruvate dehydrogenase E2 subunit; n=3;
Nyctotherus ovalis|Rep: Pyruvate dehydrogenase E2
subunit - Nyctotherus ovalis
Length = 485
Score = 124 bits (298), Expect = 3e-27
Identities = 57/112 (50%), Positives = 82/112 (73%), Gaps = 2/112 (1%)
Frame = +3
Query: 252 RYYSSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEE 431
R +SS P H ++LP LSPTM G I W KKEGD ++ GD++C++ETDKAT+G+E E+
Sbjct: 49 RAFSSYPEHKVLDLPNLSPTMTKGYITKWYKKEGDPVTAGDVICDVETDKATVGYEMVED 108
Query: 432 GYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSS--PATPQKPA 581
G +AKIL+P G+K VP+GK + I+V + DVAAFKD+K +++ PA ++ A
Sbjct: 109 GVIAKILMPEGSKEVPLGKPVAIMVTEAKDVAAFKDYKPEAAAKPAAKKEEA 160
>UniRef50_P20285 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=40; Eukaryota|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex, mitochondrial
precursor - Neurospora crassa
Length = 458
Score = 120 bits (289), Expect = 4e-26
Identities = 67/140 (47%), Positives = 85/140 (60%), Gaps = 2/140 (1%)
Frame = +3
Query: 180 VTNKLLEHAQNQTVLSTPQWTVQMRYYSSLPSHIKVNLPALSPTMESGSIVSWEKKEGDK 359
++ + L HA V + P T R+Y+S P H V +PALSPTM SG I +W+KK GDK
Sbjct: 6 LSRQALRHASVARV-ALPSLT---RWYASYPPHTVVKMPALSPTMTSGGIGAWQKKPGDK 61
Query: 360 LSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKD 539
+ G++L EIETDKA M FE EEG LAKIL +G K V VG + I+V + DV AFKD
Sbjct: 62 IEPGEVLVEIETDKAQMDFEFQEEGVLAKILKDSGEKDVAVGNPIAILVEEGTDVNAFKD 121
Query: 540 F--KDDSSPATPQKPASQDK 593
F KD +P P + K
Sbjct: 122 FTLKDAGGETSPAVPKDEPK 141
>UniRef50_Q8RWN9 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component 2 of pyruvate dehydrogenase
complex, mitochondrial precursor; n=14; cellular
organisms|Rep: Dihydrolipoyllysine-residue
acetyltransferase component 2 of pyruvate dehydrogenase
complex, mitochondrial precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 539
Score = 119 bits (286), Expect = 9e-26
Identities = 55/110 (50%), Positives = 78/110 (70%), Gaps = 3/110 (2%)
Frame = +3
Query: 261 SSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYL 440
S LP H ++ +P+LSPTM G+I W KKEGDK++ G++LCE+ETDKAT+ E EEG+L
Sbjct: 106 SDLPPHQEIGMPSLSPTMTEGNIARWLKKEGDKVAPGEVLCEVETDKATVEMECMEEGFL 165
Query: 441 AKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDF--KDDSSPATPQ-KPA 581
AKI+ G K + VG+++ I V D++D+ FKD+ D+ PA P+ KPA
Sbjct: 166 AKIVKEEGAKEIQVGEVIAITVEDEDDIQKFKDYTPSSDTGPAAPEAKPA 215
>UniRef50_Q0WQF7 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component 1 of pyruvate dehydrogenase
complex, mitochondrial precursor; n=4;
Magnoliophyta|Rep: Dihydrolipoyllysine-residue
acetyltransferase component 1 of pyruvate dehydrogenase
complex, mitochondrial precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 637
Score = 117 bits (282), Expect = 3e-25
Identities = 56/99 (56%), Positives = 69/99 (69%)
Frame = +3
Query: 261 SSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYL 440
S LP H+ + +PALSPTM G+I W KKEGDK+ GD++ EIETDKAT+ FE+ EEGYL
Sbjct: 207 SDLPPHVVLEMPALSPTMNQGNIAKWWKKEGDKIEVGDVIGEIETDKATLEFESLEEGYL 266
Query: 441 AKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSS 557
AKILIP G+K V VGK + +IV D + A K SS
Sbjct: 267 AKILIPEGSKDVAVGKPIALIVEDAESIEAIKSSSAGSS 305
Score = 105 bits (253), Expect = 9e-22
Identities = 45/78 (57%), Positives = 63/78 (80%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+PALSPTM G++V W KKEGDK+ GD+LCEIETDKAT+ FE+ EEG+LAKIL+ G+K
Sbjct: 90 MPALSPTMSHGNVVKWMKKEGDKVEVGDVLCEIETDKATVEFESQEEGFLAKILVTEGSK 149
Query: 471 GVPVGKLLCIIVGDQNDV 524
+PV + + I+V +++D+
Sbjct: 150 DIPVNEPIAIMVEEEDDI 167
>UniRef50_Q9SXV7 Cluster: Dihydrolipoamide acetyltransferase; n=1;
Lithospermum erythrorhizon|Rep: Dihydrolipoamide
acetyltransferase - Lithospermum erythrorhizon
Length = 189
Score = 115 bits (276), Expect = 2e-24
Identities = 52/93 (55%), Positives = 73/93 (78%), Gaps = 1/93 (1%)
Frame = +3
Query: 249 MRYYSSL-PSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETP 425
+R++SS P +++PALSPTM G+I W KKEGDK++ GD+LCEIETDKAT+ +E+
Sbjct: 63 VRHFSSADPPQTVLSMPALSPTMSQGNIAKWLKKEGDKIAAGDVLCEIETDKATLEYESV 122
Query: 426 EEGYLAKILIPAGTKGVPVGKLLCIIVGDQNDV 524
E+G+LAKIL+P G+K VPVGK + I V +Q+D+
Sbjct: 123 EDGFLAKILVPDGSKDVPVGKPIAITVEEQDDL 155
>UniRef50_A2WZU5 Cluster: Putative uncharacterized protein; n=2; Oryza
sativa|Rep: Putative uncharacterized protein - Oryza
sativa subsp. indica (Rice)
Length = 1812
Score = 114 bits (274), Expect = 3e-24
Identities = 52/111 (46%), Positives = 76/111 (68%), Gaps = 2/111 (1%)
Frame = +3
Query: 261 SSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYL 440
+ LP H ++ +P+LSPTM G+I W KKEGDK+S G++LCE+ETDKAT+ E EE YL
Sbjct: 1381 ADLPPHQEIGMPSLSPTMTEGNIARWLKKEGDKVSPGEVLCEVETDKATVEMECMEESYL 1440
Query: 441 AKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSS--PATPQKPASQ 587
AKI+ G K + VG+++ + V ++ D+ FKD+K +S PA P + +Q
Sbjct: 1441 AKIIHGDGAKEIKVGEIIAVTVEEEGDLERFKDYKPSTSAVPAAPSELKAQ 1491
>UniRef50_A3BC27 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 549
Score = 113 bits (273), Expect = 4e-24
Identities = 60/143 (41%), Positives = 86/143 (60%)
Frame = +3
Query: 156 STELAKRKVTNKLLEHAQNQTVLSTPQWTVQMRYYSSLPSHIKVNLPALSPTMESGSIVS 335
ST + ++ + L Q Q + + + +R + P H+ V +PALSPTM G+I
Sbjct: 111 STAIGPARLLWQQLIGLQQQAMGTVSACSSWIRPTARFPPHLVVGMPALSPTMNQGNIAK 170
Query: 336 WEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTKGVPVGKLLCIIVGDQ 515
W K+EG+K+ GD++CEIETDKAT+ FE+ EEGYLAKIL P G+K V VG+ + + V D
Sbjct: 171 WRKQEGEKIEVGDVICEIETDKATLEFESLEEGYLAKILAPEGSKDVQVGQPIAVTVEDL 230
Query: 516 NDVAAFKDFKDDSSPATPQKPAS 584
D+ K+ D+S QK S
Sbjct: 231 EDI---KNIPADASFGGEQKEQS 250
>UniRef50_Q6PLQ2 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Chlamydomonas reinhardtii|Rep: Dihydrolipoamide
S-acetyltransferase - Chlamydomonas reinhardtii
Length = 643
Score = 112 bits (269), Expect = 1e-23
Identities = 49/114 (42%), Positives = 74/114 (64%)
Frame = +3
Query: 243 VQMRYYSSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFET 422
V R +S +P+H V +PALSPTM G+I W K G ++S G +L +IETDKAT+ FE
Sbjct: 47 VLSRCFSGVPAHTIVGMPALSPTMSQGNIAKWHVKPGQEVSPGSVLADIETDKATLAFEN 106
Query: 423 PEEGYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPAS 584
+EG++AK+L+P G + +P+G+ + ++V D + VAAF +F S PA+
Sbjct: 107 QDEGFVAKLLVPDGARDIPIGQPVLVLVEDASSVAAFANFTPGQSAPADAAPAA 160
Score = 92.7 bits (220), Expect = 9e-18
Identities = 44/106 (41%), Positives = 66/106 (62%), Gaps = 1/106 (0%)
Frame = +3
Query: 270 PSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFE-TPEEGYLAK 446
P H ++ +P+LSPTM+ G+IV+W+ G + GD+L +IETDKAT+ +E EEGY+A
Sbjct: 180 PPHTRLTMPSLSPTMDRGNIVAWKVSPGAAIKAGDVLADIETDKATLAYEAVAEEGYVAA 239
Query: 447 ILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPAS 584
+L+P GT+ V VG L ++V +AAF + + A P S
Sbjct: 240 LLVPEGTRDVAVGTPLALLVEAPEHLAAFARLTPEQAHALALGPQS 285
>UniRef50_P36413 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor; n=2; Dictyostelium
discoideum|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex, mitochondrial precursor - Dictyostelium
discoideum (Slime mold)
Length = 592
Score = 109 bits (263), Expect = 6e-23
Identities = 49/120 (40%), Positives = 75/120 (62%), Gaps = 1/120 (0%)
Frame = +3
Query: 231 PQWTVQMRYYSSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATM 410
P+ + + P+H V +PALSP+ME+G I SW KKEGD++ GD + E+ETDKATM
Sbjct: 148 PKQEAPKKSTKTYPAHKVVGMPALSPSMETGGIASWTKKEGDQIKAGDAIAEVETDKATM 207
Query: 411 GFETPE-EGYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQ 587
F+ + GYLAKIL+P GT G+ + + +CIIV ++ D F D+ + ++ + +
Sbjct: 208 DFQYEDGNGYLAKILVPGGTSGIQINQPVCIIVKNKEDCDKFADYSVEEQSSSSSSSSQE 267
Score = 103 bits (248), Expect = 4e-21
Identities = 57/117 (48%), Positives = 78/117 (66%), Gaps = 3/117 (2%)
Frame = +3
Query: 252 RYYSSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEE 431
R YSS I +PALSP+M G+IV W+KKEGD++ GD++ E+ETDKATM
Sbjct: 35 RSYSSKGKEI--TMPALSPSMTVGNIVQWKKKEGDQIKAGDVIREVETDKATMDSYEDGN 92
Query: 432 GYLAKILIPAGTKGVPVGKLLCIIVGDQNDV-AAFKDFKDDS-SPATP-QKPASQDK 593
GYLAKILIP GTKG+ + K + IIV + D+ +A K++K S + +TP Q+ A + K
Sbjct: 93 GYLAKILIPEGTKGIEINKPIAIIVSKKEDIESAVKNYKPSSQASSTPVQEEAPKPK 149
>UniRef50_A7SJI4 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 396
Score = 105 bits (251), Expect = 2e-21
Identities = 48/77 (62%), Positives = 60/77 (77%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+PALSPTME+G+IVSW KKEGD + GD LCEIETDKAT+ +T E+G LAKI+IP GTK
Sbjct: 1 MPALSPTMETGTIVSWLKKEGDTIEPGDALCEIETDKATLTLDTDEQGVLAKIVIPPGTK 60
Query: 471 GVPVGKLLCIIVGDQND 521
V V +L+ +IV + D
Sbjct: 61 NVKVNELIALIVEEGED 77
>UniRef50_Q9R9N3 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=29; Alphaproteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Rhizobium meliloti
(Sinorhizobium meliloti)
Length = 447
Score = 101 bits (243), Expect = 2e-20
Identities = 46/97 (47%), Positives = 65/97 (67%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I + +PALSPTME G++ W KEGDK+ GD++ EIETDKATM E +EG +AKI++P
Sbjct: 3 INITMPALSPTMEEGNLAKWLVKEGDKVKSGDVIAEIETDKATMEVEAVDEGTVAKIVVP 62
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATP 569
AGT+GV V L+ ++ + DVA + ++ A P
Sbjct: 63 AGTEGVKVNALIAVLAAEGEDVATAAKGGNGAAGAVP 99
>UniRef50_A4RXN8 Cluster: Predicted protein; n=3; cellular
organisms|Rep: Predicted protein - Ostreococcus
lucimarinus CCE9901
Length = 421
Score = 99.5 bits (237), Expect = 8e-20
Identities = 46/98 (46%), Positives = 63/98 (64%), Gaps = 1/98 (1%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+PALSPTME G I W + GD++ GD + ++ETDKATM E ++GYLA IL+P G
Sbjct: 1 MPALSPTMERGGIARWHRAIGDEIKAGDAIADVETDKATMAMEATDDGYLAAILVPEGAT 60
Query: 471 GVPVGKLLCIIVGDQNDVAAFKDFKDDSSPAT-PQKPA 581
V VG +C++ + + VAAFKD+K + T P K A
Sbjct: 61 DVEVGTPVCVMCEEASAVAAFKDYKATETVTTEPAKSA 98
>UniRef50_Q6KCM0 Cluster: Dihydrolipoyl transacetylase; n=1; Euglena
gracilis|Rep: Dihydrolipoyl transacetylase - Euglena
gracilis
Length = 434
Score = 99.1 bits (236), Expect = 1e-19
Identities = 47/104 (45%), Positives = 70/104 (67%), Gaps = 3/104 (2%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFE-TPEEGYLAKILIP 458
K+ +PALSPTME+G+I +W+KK GDKL GD+LC +ETDKAT+ FE +EG +A++ +
Sbjct: 22 KILMPALSPTMEAGTIATWKKKVGDKLRPGDVLCSVETDKATLDFEWAGDEGIVAQLALE 81
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFK--DFKDDSSPATPQKPAS 584
G + VPVG + ++ D++D+ A K D +S A PA+
Sbjct: 82 PGHEPVPVGTPIAVLADDESDLPAAKAMDLSQGTSKAAKSSPAA 125
>UniRef50_UPI0000ECB9E1 Cluster: Apoptosis inhibitor 5 (API-5).;
n=3; Amniota|Rep: Apoptosis inhibitor 5 (API-5). -
Gallus gallus
Length = 458
Score = 98.7 bits (235), Expect = 1e-19
Identities = 51/100 (51%), Positives = 67/100 (67%), Gaps = 3/100 (3%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
IKV +PALSPTME G+IV W KKEG+ ++ GD LCEIETDKA + E+ ++G LAKIL+
Sbjct: 51 IKVLMPALSPTMEEGNIVKWLKKEGEMVNAGDALCEIETDKAVVTMESSDDGILAKILVE 110
Query: 459 AGTKGVPVGKLLCIIVGDQND---VAAFKDFKDDSSPATP 569
G+K V +G L+ ++V + D V D D SS A P
Sbjct: 111 EGSKNVRLGSLIGLLVEEGQDWKQVEIPADANDQSSLAPP 150
>UniRef50_Q6N5V4 Cluster: Pyruvate dehydrogenase E1 beta subunit;
n=24; cellular organisms|Rep: Pyruvate dehydrogenase E1
beta subunit - Rhodopseudomonas palustris
Length = 469
Score = 98.3 bits (234), Expect = 2e-19
Identities = 54/103 (52%), Positives = 64/103 (62%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I+V +PALSPTME G++ W KKEGDK+ GD++ EIETDKATM E +EG L KILIP
Sbjct: 3 IQVLMPALSPTMEKGNLSKWLKKEGDKVKSGDVIAEIETDKATMEVEAADEGTLGKILIP 62
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQ 587
GT V V + I+GD A D S PA Q ASQ
Sbjct: 63 EGTNDVAVNTPIATILGDGESAA---DADKASDPAA-QSKASQ 101
>UniRef50_UPI00015A4520 Cluster: UPI00015A4520 related cluster; n=3;
Danio rerio|Rep: UPI00015A4520 UniRef100 entry - Danio
rerio
Length = 494
Score = 97.9 bits (233), Expect = 2e-19
Identities = 43/81 (53%), Positives = 61/81 (75%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
+KV +PALSPTME G+IV W KKEG+ ++ GD LCEIETDKA + E+ E+G LA+IL+
Sbjct: 63 LKVQMPALSPTMEEGNIVKWLKKEGEDVAAGDALCEIETDKAVVVMESNEDGVLARILVQ 122
Query: 459 AGTKGVPVGKLLCIIVGDQND 521
G++GV +G L+ ++V + D
Sbjct: 123 EGSRGVRLGTLIALMVSEGED 143
>UniRef50_Q68FJ5 Cluster: MGC86218 protein; n=3; Tetrapoda|Rep:
MGC86218 protein - Xenopus laevis (African clawed frog)
Length = 478
Score = 97.9 bits (233), Expect = 2e-19
Identities = 43/81 (53%), Positives = 61/81 (75%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
++V++PALSPTME G+IV W KKEG+ +S GD LCEIETDKA + E+ ++G LAKIL+
Sbjct: 44 VQVSMPALSPTMEEGNIVKWLKKEGESVSAGDALCEIETDKAVVTMESNDDGVLAKILVE 103
Query: 459 AGTKGVPVGKLLCIIVGDQND 521
G+K V +G L+ ++V + D
Sbjct: 104 EGSKNVRLGSLIALLVEEGQD 124
>UniRef50_A3WC78 Cluster: Pyruvate dehydrogenase E2 component; n=2;
Alphaproteobacteria|Rep: Pyruvate dehydrogenase E2
component - Erythrobacter sp. NAP1
Length = 463
Score = 97.9 bits (233), Expect = 2e-19
Identities = 46/105 (43%), Positives = 67/105 (63%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I++ +PALSPTME G++ W K GD+++ GD++ EIETDKATM FE +EG LA IL+
Sbjct: 3 IELKMPALSPTMEEGTLARWLVKVGDEIASGDIMAEIETDKATMEFEAVDEGTLAAILVE 62
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQDK 593
GT+ V VG ++ ++ + DV+ D++PA PA K
Sbjct: 63 EGTENVAVGTVIAMLAEEGEDVSDVSAPSGDAAPAPTPAPAPAPK 107
>UniRef50_O00330 Cluster: Pyruvate dehydrogenase protein X
component, mitochondrial precursor; n=26; Amniota|Rep:
Pyruvate dehydrogenase protein X component,
mitochondrial precursor - Homo sapiens (Human)
Length = 501
Score = 97.1 bits (231), Expect = 4e-19
Identities = 46/101 (45%), Positives = 66/101 (65%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
IK+ +P+LSPTME G+IV W KKEG+ +S GD LCEIETDKA + + ++G LAKI++
Sbjct: 57 IKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVE 116
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPA 581
G+K + +G L+ +IV + D + KD P KP+
Sbjct: 117 EGSKNIRLGSLIGLIVEEGEDWKHVEIPKDVGPPPPVSKPS 157
>UniRef50_Q4PHZ8 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 341
Score = 95.9 bits (228), Expect = 1e-18
Identities = 45/95 (47%), Positives = 63/95 (66%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
K +PA+SPTM SG I +W+ KEG S GD+L EIETDKATM E E+G LAKI++
Sbjct: 41 KFAMPAMSPTMTSGGIAAWKLKEGQAFSAGDVLLEIETDKATMDVEAQEDGVLAKIIVQD 100
Query: 462 GTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPAT 566
G+K V VGK + ++ + +D++ + KDD + T
Sbjct: 101 GSKDVSVGKTIAMLAEEGDDISNVEVPKDDEATCT 135
>UniRef50_Q92HK7 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=10; Rickettsia|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Rickettsia conorii
Length = 412
Score = 94.3 bits (224), Expect = 3e-18
Identities = 48/108 (44%), Positives = 72/108 (66%), Gaps = 3/108 (2%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
IK+ +PALSPTM G++ W KKEGDK++ G+++ EIETDKATM E +EG LAKI+IP
Sbjct: 3 IKILMPALSPTMTEGNLARWLKKEGDKVNPGEVIAEIETDKATMEVEAVDEGILAKIVIP 62
Query: 459 AGTKGVPVGKLLCIIV---GDQNDVAAFKDFKDDSSPATPQKPASQDK 593
++ VPV L+ ++ ++ D+ AF K++S +P+ A+ K
Sbjct: 63 QNSQNVPVNSLIAVLSEEGEEKTDIDAF-IAKNNSVSPSPKTDANLPK 109
>UniRef50_Q73FZ4 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=9;
Rickettsiales|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Wolbachia pipientis wMel
Length = 454
Score = 93.9 bits (223), Expect = 4e-18
Identities = 46/105 (43%), Positives = 68/105 (64%), Gaps = 2/105 (1%)
Frame = +3
Query: 279 IKVNLPALSPTMES--GSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKIL 452
I++ +PALSPTM G IV W KKE DK+ GD++ EIETDKA M FE+ +EG LAKIL
Sbjct: 3 IEILMPALSPTMSKAGGKIVKWHKKEQDKVEVGDVIAEIETDKAIMEFESIDEGVLAKIL 62
Query: 453 IPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQ 587
+ GT GVPV + + +++ + D +A ++ S + +K ++
Sbjct: 63 VTEGTSGVPVNQPIALMLEEGEDESALNNYTSTSINSAVKKEVTK 107
>UniRef50_O66113 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=99; Bacteria|Rep: Pyruvate dehydrogenase
E1 component subunit beta - Zymomonas mobilis
Length = 462
Score = 93.9 bits (223), Expect = 4e-18
Identities = 48/104 (46%), Positives = 68/104 (65%), Gaps = 5/104 (4%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I++ +PALSPTME G++ W KEGD + G++L EIETDKA M FE +EG + KILIP
Sbjct: 3 IELKMPALSPTMEEGTLTRWLVKEGDSIKAGEILAEIETDKAIMEFEAVDEGVITKILIP 62
Query: 459 AGTKGVPVGKLLCIIVGDQNDV----AAFKDFKDDSSP-ATPQK 575
G++ V VG + + D NDV A+ + ++S+P A+P K
Sbjct: 63 EGSENVKVGTAIAYLGTDANDVTLDGASAETKAEESAPVASPAK 106
>UniRef50_Q5BXT9 Cluster: SJCHGC06137 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06137 protein - Schistosoma
japonicum (Blood fluke)
Length = 185
Score = 93.5 bits (222), Expect = 5e-18
Identities = 37/75 (49%), Positives = 57/75 (76%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
+ + +P+LSPTM G+IV+W K EG+ ++ GD+LCE++TDKA + FE+ E+G LAKIL P
Sbjct: 27 VNIKMPSLSPTMSDGTIVNWLKNEGEDVTAGDVLCEVQTDKAVISFESDEDGVLAKILAP 86
Query: 459 AGTKGVPVGKLLCII 503
AG+ + VG L+ ++
Sbjct: 87 AGSSSIKVGGLIAVL 101
>UniRef50_Q5KEE0 Cluster: Pyruvate dehydrogenase protein x
component, mitochondrial, putative; n=2; Filobasidiella
neoformans|Rep: Pyruvate dehydrogenase protein x
component, mitochondrial, putative - Cryptococcus
neoformans (Filobasidiella neoformans)
Length = 337
Score = 93.5 bits (222), Expect = 5e-18
Identities = 39/97 (40%), Positives = 65/97 (67%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+PA+SPTM G I SW+K EG+ + GD+L E+ETDKAT+ E E+G + KI++ AG +
Sbjct: 35 MPAMSPTMTEGGIASWKKNEGESFAAGDVLLEVETDKATIDVEAQEDGVMGKIIVQAGAQ 94
Query: 471 GVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPA 581
+PVG+++ ++ + +D+++ + + PA P PA
Sbjct: 95 KIPVGQVIAVLAEEGDDLSSI-TIPEAAPPAPPAAPA 130
>UniRef50_Q2H6F4 Cluster: Putative uncharacterized protein; n=3;
Pezizomycotina|Rep: Putative uncharacterized protein -
Chaetomium globosum (Soil fungus)
Length = 430
Score = 93.5 bits (222), Expect = 5e-18
Identities = 45/99 (45%), Positives = 64/99 (64%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+PALSPTM G+I +W+ KEG+K S GD+L EIETDKATM E E+G L K++ G+K
Sbjct: 42 MPALSPTMTEGNIAAWKIKEGEKFSAGDVLLEIETDKATMDVEAQEDGTLMKVMQGDGSK 101
Query: 471 GVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQ 587
GV VG + +I + +D++ D++ AT AS+
Sbjct: 102 GVQVGTRIAVIAEEGDDISTLNIPADENPQATKAAEASK 140
>UniRef50_UPI0000E4A22B Cluster: PREDICTED: similar to pyruvate
dehydrogenase complex, component X; n=4;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
pyruvate dehydrogenase complex, component X -
Strongylocentrotus purpuratus
Length = 482
Score = 92.3 bits (219), Expect = 1e-17
Identities = 46/105 (43%), Positives = 67/105 (63%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I + +PALSPTM G+IVSW K EGD ++ GD +CEIETDKAT+ + ++G +AKIL+P
Sbjct: 55 INLIMPALSPTMTEGTIVSWLKAEGDPIAAGDGICEIETDKATVIMDADDDGIMAKILVP 114
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQDK 593
G+K +P+ L+ ++V + D +KD D + A P K
Sbjct: 115 EGSKNIPITALIGLMVPEGED---YKDV-DMPTQAAPTSTGDSPK 155
>UniRef50_UPI0000DB7177 Cluster: PREDICTED: similar to Pyruvate
dehydrogenase protein X component, mitochondrial
precursor (Dihydrolipoamide dehydrogenase-binding
protein of pyruvate dehydrogenase complex)
(Lipoyl-containing pyruvate dehydrogenase complex
component X) (E3-binding protein) (E...; n=1; Apis
mellifera|Rep: PREDICTED: similar to Pyruvate
dehydrogenase protein X component, mitochondrial
precursor (Dihydrolipoamide dehydrogenase-binding
protein of pyruvate dehydrogenase complex)
(Lipoyl-containing pyruvate dehydrogenase complex
component X) (E3-binding protein) (E... - Apis mellifera
Length = 598
Score = 92.3 bits (219), Expect = 1e-17
Identities = 45/82 (54%), Positives = 57/82 (69%)
Frame = +3
Query: 261 SSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYL 440
SS P + +PALSPTM SG+IV W KKEG+K+ GD + EI+TDKA M FE +EG
Sbjct: 158 SSTPPPSNIGMPALSPTMTSGTIVKWLKKEGEKIEPGDAVAEIQTDKAVMTFEIEDEGIF 217
Query: 441 AKILIPAGTKGVPVGKLLCIIV 506
AKILIP G++ VG+L+ I V
Sbjct: 218 AKILIPEGSQ-AEVGELIAITV 238
Score = 82.2 bits (194), Expect = 1e-14
Identities = 41/98 (41%), Positives = 59/98 (60%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+P+LSPTME G+IV W KKEGDK+ GD + +I+TDKA + E +E LAKI++ G +
Sbjct: 50 MPSLSPTMEKGTIVKWIKKEGDKIEAGDAVADIQTDKAVVTLELEDESILAKIIVGEGIQ 109
Query: 471 GVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPAS 584
+ VG L+ + V D + + D+ TP AS
Sbjct: 110 DIKVGTLIALTVDVDEDWKSVE--MPDNVSVTPPVTAS 145
>UniRef50_Q7RWS2 Cluster: Putative uncharacterized protein
NCU00050.1; n=2; Sordariomycetes|Rep: Putative
uncharacterized protein NCU00050.1 - Neurospora crassa
Length = 413
Score = 92.3 bits (219), Expect = 1e-17
Identities = 46/109 (42%), Positives = 67/109 (61%), Gaps = 8/109 (7%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+PALSPTM G+I +W KEGDK S GD+L EIETDKATM E ++G + KI+ G K
Sbjct: 23 MPALSPTMTEGNIATWRVKEGDKFSAGDVLLEIETDKATMDVEAQDDGVMVKIMKNDGAK 82
Query: 471 GVPVGKLLCIIVGDQNDVAAFKDFKD--------DSSPATPQKPASQDK 593
GV VG + +I + +D+++ + D +S+P+ P P + D+
Sbjct: 83 GVAVGARIAVIAEEGDDISSLEIPADAAPQSKPAESAPSAPPPPTTADQ 131
>UniRef50_Q2GCH9 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Neorickettsia sennetsu str. Miyayama|Rep: Pyruvate
dehydrogenase complex, E2 component, dihydrolipoamide
acetyltransferase - Neorickettsia sennetsu (strain
Miyayama)
Length = 403
Score = 91.5 bits (217), Expect = 2e-17
Identities = 45/106 (42%), Positives = 62/106 (58%), Gaps = 2/106 (1%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
+K+ +PALSPTM+ G++ W EG+K+ G ++ EIETDKATM FE +EG L KILIP
Sbjct: 3 VKILMPALSPTMKEGTLAKWLVSEGEKIEAGQVIAEIETDKATMEFEAVDEGVLGKILIP 62
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFKD--DSSPATPQKPASQD 590
A T GV V + + +++ D K F D T K + D
Sbjct: 63 AKTAGVKVNQPIAVLLDDGEGEKELKKFLSTIDKPTVTDNKAETSD 108
>UniRef50_O66119 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=31; Bacteria|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex - Zymomonas mobilis
Length = 440
Score = 91.5 bits (217), Expect = 2e-17
Identities = 40/83 (48%), Positives = 58/83 (69%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I+V +PALSPTM G++ W KEGD + GD+L EIETDKA M FET + G +AKIL+P
Sbjct: 3 IEVKMPALSPTMTEGTLAKWLVKEGDAVKAGDILAEIETDKAIMEFETVDAGIIAKILVP 62
Query: 459 AGTKGVPVGKLLCIIVGDQNDVA 527
G++ + VG+++ ++ DV+
Sbjct: 63 EGSENIAVGQVIAVMAEAGEDVS 85
>UniRef50_O94709 Cluster: Probable pyruvate dehydrogenase protein X
component, mitochondrial precursor; n=1;
Schizosaccharomyces pombe|Rep: Probable pyruvate
dehydrogenase protein X component, mitochondrial
precursor - Schizosaccharomyces pombe (Fission yeast)
Length = 456
Score = 90.6 bits (215), Expect = 4e-17
Identities = 52/140 (37%), Positives = 83/140 (59%), Gaps = 6/140 (4%)
Frame = +3
Query: 192 LLEHAQNQTVLSTP---QWTVQMRYY--SSLPSHIKV-NLPALSPTMESGSIVSWEKKEG 353
+L+H +Q V ++ +V+ RY+ S+L + +PALSPTME G+I W KEG
Sbjct: 1 MLKHYIHQCVKASSCKHSLSVKQRYFHCSALNGVASMFRMPALSPTMEEGNITKWHFKEG 60
Query: 354 DKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAF 533
D GD+L E+ETDKATM E + G LAK+LI G+ +PVGK + I+ ++++
Sbjct: 61 DSFKSGDILLEVETDKATMDVEVQDNGILAKVLIEKGS-NIPVGKNIAIVADAEDNLKDL 119
Query: 534 KDFKDDSSPATPQKPASQDK 593
+ KD++S +S+++
Sbjct: 120 ELPKDEASSEEQSFSSSKEE 139
>UniRef50_UPI0000509C9C Cluster: hypothetical protein LOC549074;
n=1; Xenopus tropicalis|Rep: hypothetical protein
LOC549074 - Xenopus tropicalis
Length = 191
Score = 89.8 bits (213), Expect = 7e-17
Identities = 37/57 (64%), Positives = 49/57 (85%)
Frame = +3
Query: 312 MESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTKGVPV 482
M+ G+I WEKKEGDK++EGDL+ E+ETDKAT+GFE+ EEGY+AKIL+ GT+ VP+
Sbjct: 1 MQMGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEEGYMAKILVAEGTRDVPI 57
>UniRef50_A3UCP2 Cluster: Dihydrolipoamide acetyltransferase; n=1;
Oceanicaulis alexandrii HTCC2633|Rep: Dihydrolipoamide
acetyltransferase - Oceanicaulis alexandrii HTCC2633
Length = 264
Score = 89.8 bits (213), Expect = 7e-17
Identities = 40/89 (44%), Positives = 61/89 (68%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I++ +PALSPTME G++ W KEGD ++ GD++ EIETDKATM E +EG + KIL+
Sbjct: 3 IEILMPALSPTMEEGTLSKWTVKEGDTVNSGDVIAEIETDKATMEVEAVDEGVIGKILVE 62
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFK 545
GT+GV V + +++ D D +A + ++
Sbjct: 63 EGTEGVKVNAPIGLLLEDGEDKSALEGYE 91
>UniRef50_Q5KIM3 Cluster: Dihydrolipoyllysine-residue
acetyltransferase, putative; n=2; Basidiomycota|Rep:
Dihydrolipoyllysine-residue acetyltransferase, putative
- Cryptococcus neoformans (Filobasidiella neoformans)
Length = 479
Score = 89.4 bits (212), Expect = 9e-17
Identities = 45/117 (38%), Positives = 72/117 (61%), Gaps = 6/117 (5%)
Frame = +3
Query: 261 SSLPSHI--KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEG 434
+S PS++ K +PA+SPTM G + W+KKEG+ S GD+L EIETDKAT+ E ++G
Sbjct: 28 TSAPSNVLSKFAMPAMSPTMTEGGVAQWKKKEGESFSAGDVLIEIETDKATIDVEAQDDG 87
Query: 435 YLAKILIPAGTKGVPVGKLLCIIVGDQNDV----AAFKDFKDDSSPATPQKPASQDK 593
+AKI+ GTK + VG + II + +D+ A + + +S+P+ + ++K
Sbjct: 88 IMAKIIAQDGTKNIAVGTPIAIIGEEGDDLSQADALAAESQSESAPSQKEAAPKEEK 144
>UniRef50_UPI0000383A75 Cluster: COG0508: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzymes; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG0508:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dihydrolipoamide acyltransferase (E2) component, and
related enzymes - Magnetospirillum magnetotacticum MS-1
Length = 188
Score = 88.2 bits (209), Expect = 2e-16
Identities = 42/93 (45%), Positives = 55/93 (59%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+PALSPTM G + W K EGD + GD+L EIETDKATM E E+G L KIL+ GT+
Sbjct: 1 MPALSPTMTEGKLAKWLKAEGDAVKSGDILAEIETDKATMEMEAVEDGVLGKILVQGGTE 60
Query: 471 GVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATP 569
GV V + +I+ + D +A + A P
Sbjct: 61 GVAVNTPIALILEEGEDASALSASAPAPATAAP 93
>UniRef50_A4RM31 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 439
Score = 88.2 bits (209), Expect = 2e-16
Identities = 43/91 (47%), Positives = 57/91 (62%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+PALSPTM G+I +W KEGDK GD+L EIETDKATM E EEG + KIL G K
Sbjct: 40 MPALSPTMTEGNIATWRVKEGDKFQAGDVLLEIETDKATMDVEAQEEGVVMKILQGDGAK 99
Query: 471 GVPVGKLLCIIVGDQNDVAAFKDFKDDSSPA 563
V VG + ++ + +DV+ + +D + A
Sbjct: 100 AVKVGARIAVLAEEGDDVSTLEIPAEDQTGA 130
>UniRef50_Q2GI07 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=6;
Anaplasmataceae|Rep: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Ehrlichia chaffeensis (strain Arkansas)
Length = 416
Score = 86.6 bits (205), Expect = 6e-16
Identities = 43/105 (40%), Positives = 64/105 (60%), Gaps = 1/105 (0%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFE-TPEEGYLAKILI 455
I+V +PALSPTM+SG+I W K EGD + GD++ +IETDKA M E T E+G + KI
Sbjct: 3 IEVLMPALSPTMKSGTIRKWYKAEGDVVKSGDVIADIETDKAVMECEYTDEDGIMGKIFF 62
Query: 456 PAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQD 590
G+K + V +L+ +I D+ D+A ++ + + A QD
Sbjct: 63 AEGSKNIEVNQLIALIAVDEQDLAKVHSYEKGDNVVKNELVALQD 107
>UniRef50_Q6CNU8 Cluster: Kluyveromyces lactis strain NRRL Y-1140
chromosome E of strain NRRL Y- 1140 of Kluyveromyces
lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
lactis strain NRRL Y-1140 chromosome E of strain NRRL Y-
1140 of Kluyveromyces lactis - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 405
Score = 86.2 bits (204), Expect = 8e-16
Identities = 43/100 (43%), Positives = 61/100 (61%), Gaps = 5/100 (5%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+PA+SPTME G +V W+ K GD S GD+L E+ETDKAT+ E ++G LAKIL G K
Sbjct: 29 MPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVEAQDDGKLAKILKENGAK 88
Query: 471 GVPVGKLLCIIVGDQNDVAAFK-----DFKDDSSPATPQK 575
+PVG+ + I +D+A + + K +S P +K
Sbjct: 89 DIPVGEPIAYIADVDDDLATLEFPKPVEAKKESKPVETKK 128
>UniRef50_Q4DYI5 Cluster: Dihydrolipoamide acetyltransferase,
putative; n=2; Trypanosomatidae|Rep: Dihydrolipoamide
acetyltransferase, putative - Trypanosoma cruzi
Length = 269
Score = 84.2 bits (199), Expect = 3e-15
Identities = 38/88 (43%), Positives = 62/88 (70%), Gaps = 1/88 (1%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGF-ETPEEGYLAKILIPAGT 467
+PALSP+ME+G+IV W+KK GD ++E ++ C ++TDKA + + T + GYLAKIL +G
Sbjct: 16 MPALSPSMETGTIVEWKKKVGDLVNENEVFCTVQTDKAVVDYTNTFDAGYLAKILCHSG- 74
Query: 468 KGVPVGKLLCIIVGDQNDVAAFKDFKDD 551
+ VPV K + ++V D+ D+ D++ +
Sbjct: 75 ETVPVAKTIAVMVEDEADIPKIADYRPE 102
>UniRef50_Q1VYW1 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvatedehydrogenase
complex; n=11; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvatedehydrogenase complex - Psychroflexus torquis
ATCC 700755
Length = 572
Score = 83.0 bits (196), Expect = 8e-15
Identities = 45/104 (43%), Positives = 63/104 (60%), Gaps = 2/104 (1%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
VN+P LS TME G + W K++GDK+ EG++L EIETDKATM FE+ +G L I + G
Sbjct: 5 VNMPRLSDTMEEGVVAKWLKQKGDKVEEGEILAEIETDKATMEFESFHDGVLLHIGVEEG 64
Query: 465 TKGVPVGKLLCIIVGDQNDVAAF--KDFKDDSSPATPQKPASQD 590
+G PV LL II + D++ K++SS +K + D
Sbjct: 65 -EGAPVDTLLAIIGEEGEDISDLIKNSGKENSSDGKAEKTEAVD 107
Score = 73.7 bits (173), Expect = 5e-12
Identities = 42/104 (40%), Positives = 58/104 (55%), Gaps = 1/104 (0%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +P LS TME G++ +W K GD + EG++L EIETDKATM FE+ G L I I G
Sbjct: 135 VTMPRLSDTMEEGTVSTWLKSVGDDVKEGEILAEIETDKATMEFESFYTGKLLYIGIGEG 194
Query: 465 TKGVPVGKLLCIIVGDQNDV-AAFKDFKDDSSPATPQKPASQDK 593
+ PV +L +I + DV K K + + + +S DK
Sbjct: 195 -ESAPVDDVLAVIGPEGTDVDKVLKSLKPEGKSSKSKSDSSSDK 237
>UniRef50_A7TK36 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 405
Score = 83.0 bits (196), Expect = 8e-15
Identities = 39/99 (39%), Positives = 59/99 (59%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+PA+SPTME G IV W+ K G+ S GD+L E+ETDKA + E ++G +AKI+I G K
Sbjct: 34 MPAMSPTMEKGGIVQWKFKVGEPFSAGDVLLEVETDKAQIDVEAQDDGKIAKIIIGDGAK 93
Query: 471 GVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQ 587
VPVG + + +D++ K ++P P ++
Sbjct: 94 DVPVGDTIAFLAEVDDDLSTLKIPDVTAAPKKDAAPKTE 132
>UniRef50_P16451 Cluster: Pyruvate dehydrogenase complex protein X
component, mitochondrial precursor; n=3; Saccharomyces
cerevisiae|Rep: Pyruvate dehydrogenase complex protein X
component, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 410
Score = 82.2 bits (194), Expect = 1e-14
Identities = 43/109 (39%), Positives = 67/109 (61%), Gaps = 2/109 (1%)
Frame = +3
Query: 216 TVLSTPQWTVQMRYYSS--LPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEI 389
T+ S ++ + Y++S L + ++PA+SPTME G IVSW+ K G+ S GD++ E+
Sbjct: 10 TLKSCTRYLTKCNYHASAKLLAVKTFSMPAMSPTMEKGGIVSWKYKVGEPFSAGDVILEV 69
Query: 390 ETDKATMGFETPEEGYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFK 536
ETDK+ + E ++G LAKIL G+K V VG+ + I +D+A K
Sbjct: 70 ETDKSQIDVEALDDGKLAKILKDEGSKDVDVGEPIAYIADVDDDLATIK 118
>UniRef50_Q6CF67 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 410
Score = 81.8 bits (193), Expect = 2e-14
Identities = 41/103 (39%), Positives = 61/103 (59%), Gaps = 3/103 (2%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+PA+SPTM G IVSW+ KEGD+ S GD++ EIETDKA + E ++G +AKI G K
Sbjct: 28 MPAMSPTMTEGGIVSWKVKEGDEFSAGDVILEIETDKAQIDVEAADDGVMAKIYKKDGDK 87
Query: 471 GVPVGKLLCIIVGDQNDVAAF---KDFKDDSSPATPQKPASQD 590
+ VG + +I +D+ + D PA P++ A ++
Sbjct: 88 DIQVGDTIAVIAEPGDDIKTIDIPAPVESDGKPA-PKEEAKEE 129
>UniRef50_Q6FSM5 Cluster: Candida glabrata strain CBS138 chromosome
G complete sequence; n=1; Candida glabrata|Rep: Candida
glabrata strain CBS138 chromosome G complete sequence -
Candida glabrata (Yeast) (Torulopsis glabrata)
Length = 429
Score = 81.4 bits (192), Expect = 2e-14
Identities = 37/82 (45%), Positives = 54/82 (65%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+PA+SPTME G IVSW+ KE D + GD+L E+ETDKA + E ++G LAKI+ G+K
Sbjct: 45 MPAMSPTMEKGGIVSWKFKENDSFNAGDVLLEVETDKAQIDVEAQDDGKLAKIIRGDGSK 104
Query: 471 GVPVGKLLCIIVGDQNDVAAFK 536
V VG ++ ++D++ K
Sbjct: 105 DVLVGDVIAFTADPEDDLSTLK 126
>UniRef50_A7IFM6 Cluster: Biotin/lipoyl attachment domain-containing
protein; n=1; Xanthobacter autotrophicus Py2|Rep:
Biotin/lipoyl attachment domain-containing protein -
Xanthobacter sp. (strain Py2)
Length = 461
Score = 81.0 bits (191), Expect = 3e-14
Identities = 39/77 (50%), Positives = 51/77 (66%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
++ +PALS ME G +V W KKEG+ + GDLL EIETDKA M E +EG L ILI
Sbjct: 4 EILMPALSAGMEEGHLVRWLKKEGEAVKRGDLLAEIETDKAVMEMEAEDEGRLGPILIGD 63
Query: 462 GTKGVPVGKLLCIIVGD 512
G++GV VG L+ I+ +
Sbjct: 64 GSRGVAVGTLIASILAE 80
>UniRef50_A6DTS5 Cluster: Pyruvate dehydrogenase complex , E2
component, dihydrolipoamide acetyltransferase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Pyruvate
dehydrogenase complex , E2 component, dihydrolipoamide
acetyltransferase - Lentisphaera araneosa HTCC2155
Length = 442
Score = 80.2 bits (189), Expect = 5e-14
Identities = 39/108 (36%), Positives = 66/108 (61%), Gaps = 2/108 (1%)
Frame = +3
Query: 273 SHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKIL 452
S I + LP+LSPTM G+I W+ K GD++ G ++ I TDK+T+ +E+ EEG+L +I+
Sbjct: 2 STIMITLPSLSPTMTEGTIAEWKVKPGDEIESGQVIASIATDKSTVDYESLEEGFLREII 61
Query: 453 IPAGTKGVPVGKLLCIIV--GDQNDVAAFKDFKDDSSPATPQKPASQD 590
+ AG G PVGK++ + D++ + + S P++ AS++
Sbjct: 62 LEAGGAG-PVGKVIAVFTEEADEDYKEELEAALAEESVPEPEEEASEE 108
>UniRef50_Q4QCG0 Cluster: Dihydrolipoamide acetyltransferaselike
protein; n=2; Leishmania|Rep: Dihydrolipoamide
acetyltransferaselike protein - Leishmania major
Length = 394
Score = 80.2 bits (189), Expect = 5e-14
Identities = 41/107 (38%), Positives = 62/107 (57%), Gaps = 1/107 (0%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGF-ETPEEGYLAKILIPA 461
V +PALSP+ME+G++V W+KK G+ + E D+ C I+TDKA + + T E GYLAKI
Sbjct: 141 VFMPALSPSMETGTVVEWKKKIGELVKESDVFCTIQTDKAVVDYTNTFESGYLAKIYCGN 200
Query: 462 GTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQDKXLA 602
G + PV K + ++V D DV ++ + + P A+ A
Sbjct: 201 G-QSAPVAKTIAVMVSDAADVEKVANYYPEDAVGGPPASAADPSAAA 246
Score = 78.6 bits (185), Expect = 2e-13
Identities = 38/87 (43%), Positives = 57/87 (65%), Gaps = 1/87 (1%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGF-ETPEEGYLAKILIPA 461
V +PALSP+ME+G++V W+KK G+ + E D+ C I+TDKA + + T E GYLAKI
Sbjct: 15 VFMPALSPSMETGTVVEWKKKIGELVKESDVFCTIQTDKAVVDYTNTFESGYLAKIYCGN 74
Query: 462 GTKGVPVGKLLCIIVGDQNDVAAFKDF 542
G + PV K + ++V D DV+ ++
Sbjct: 75 G-QSAPVAKTIAVMVSDAADVSKADEY 100
>UniRef50_A6SFD7 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 379
Score = 79.8 bits (188), Expect = 7e-14
Identities = 39/100 (39%), Positives = 64/100 (64%), Gaps = 1/100 (1%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+PALSPTM G+I KEGD + GD+L EIETDKA+M E ++G +AKI + G+K
Sbjct: 1 MPALSPTMTEGNIAKRNVKEGDSFAAGDVLLEIETDKASMDVEAQDDGIMAKITMGDGSK 60
Query: 471 GVPVGKLLCIIVGDQNDVAAFK-DFKDDSSPATPQKPASQ 587
G+ VG + + +D+++ + + ++P +P++ AS+
Sbjct: 61 GIKVGTRIGALAESGDDLSSLEIPAEASAAPPSPKEEASK 100
>UniRef50_A3GI36 Cluster: Pyruvate dehydrogenase complex protein X;
n=5; Saccharomycetales|Rep: Pyruvate dehydrogenase
complex protein X - Pichia stipitis (Yeast)
Length = 418
Score = 79.4 bits (187), Expect = 9e-14
Identities = 36/101 (35%), Positives = 61/101 (60%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+PA+SPTM G IVSW+ K G+ + GD+L E+ETDKAT+ E ++G + +I++ G K
Sbjct: 37 MPAMSPTMSEGGIVSWKFKPGEAFNSGDVLLEVETDKATIDVEAVDDGKMWEIIVNDGAK 96
Query: 471 GVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQDK 593
GV VG+ + ++ ++D+ + ++ P + A K
Sbjct: 97 GVAVGEPIALLAEPEDDLLTLERPVLETKATKPAETAEAPK 137
>UniRef50_Q7NHG8 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Gloeobacter violaceus|Rep: Dihydrolipoamide
S-acetyltransferase - Gloeobacter violaceus
Length = 419
Score = 79.0 bits (186), Expect = 1e-13
Identities = 40/96 (41%), Positives = 58/96 (60%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
+V +PALS TM G IV+W+K+EGD +S D+L +E+DKA M E+ +EG LA IL+
Sbjct: 4 EVTMPALSSTMTEGKIVTWKKQEGDAVSRSDILLVVESDKADMDVESFDEGILANILVSD 63
Query: 462 GTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATP 569
G PVG ++ +I + +VA K + A P
Sbjct: 64 G-GSAPVGSVIALIAETEAEVAEAKKRPPSGTAAAP 98
>UniRef50_Q47KD8 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Thermobifida fusca YX|Rep: Pyruvate dehydrogenase
complex, E2 component, dihydrolipoamide
acetyltransferase - Thermobifida fusca (strain YX)
Length = 431
Score = 78.2 bits (184), Expect = 2e-13
Identities = 42/102 (41%), Positives = 62/102 (60%), Gaps = 2/102 (1%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
++ +P LS TME G I SW K+ GDK+S GD+L EIETDKA M +E E+GYL + +
Sbjct: 3 EIYMPRLSDTMEEGVISSWVKQVGDKVSVGDVLVEIETDKAVMEYEAYEDGYLVQQTVRE 62
Query: 462 GTKGVPVGKLLCIIVGDQNDVAAFKDFKD--DSSPATPQKPA 581
G + VP+G ++ +I + V A + + + PQ+PA
Sbjct: 63 G-ETVPIGAVIGVIADSPDAVPAAPEGGEGAEQKAEEPQQPA 103
>UniRef50_A3VIE9 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex dihydrolipoamidedehydrogenase E3 component; n=1;
Rhodobacterales bacterium HTCC2654|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex
dihydrolipoamidedehydrogenase E3 component -
Rhodobacterales bacterium HTCC2654
Length = 428
Score = 78.2 bits (184), Expect = 2e-13
Identities = 43/107 (40%), Positives = 58/107 (54%)
Frame = +3
Query: 267 LPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAK 446
LP V +P L +SG +VSW K GD +S D+L E+ETDK+TM E +GYLA
Sbjct: 103 LPEGHAVTMPQLGMAQDSGLLVSWHKSPGDAVSADDVLFEVETDKSTMEVEAGRDGYLAA 162
Query: 447 ILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQ 587
L AG + VPVG + II ++ D A + K Q PA++
Sbjct: 163 TLAEAGEE-VPVGTAVAIISAEKPDNAVARSAKATPPLKAEQTPAAE 208
Score = 63.3 bits (147), Expect = 7e-09
Identities = 32/79 (40%), Positives = 45/79 (56%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +P L ++G IVSW K G+ +S+GD L E+ETDKATM E +G+L + G
Sbjct: 5 VTMPQLGMAQDAGKIVSWLKSPGEAVSKGDALFEVETDKATMEVEAQADGFLTGVTAGEG 64
Query: 465 TKGVPVGKLLCIIVGDQND 521
+ VPVG ++ I D
Sbjct: 65 -EDVPVGAVIARISESAED 82
>UniRef50_Q9PKE7 Cluster: Pyruvate dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase, putative; n=2;
Chlamydiales|Rep: Pyruvate dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase, putative - Chlamydia
muridarum
Length = 428
Score = 77.8 bits (183), Expect = 3e-13
Identities = 34/78 (43%), Positives = 53/78 (67%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ +P LSPTME+G++V W K+ GD++ GD+L EI TDKA + E+G+L +IL+ G
Sbjct: 5 LKMPKLSPTMETGTLVKWHKQAGDEVHFGDVLLEISTDKAVLEHTASEDGWLLQILVKEG 64
Query: 465 TKGVPVGKLLCIIVGDQN 518
TK +P+G + + +QN
Sbjct: 65 TK-IPIGTPIAVFSTEQN 81
>UniRef50_Q8F4N2 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex E2; n=3;
Leptospira|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex E2 -
Leptospira interrogans
Length = 458
Score = 77.8 bits (183), Expect = 3e-13
Identities = 42/96 (43%), Positives = 56/96 (58%)
Frame = +3
Query: 300 LSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTKGVP 479
LSPTM G IV W K++GD +S G+++ E+ETDKA M E E G L +IL P GT +P
Sbjct: 10 LSPTMAEGKIVRWLKQKGDPVSPGEIIAEVETDKAVMEMEAFETGILLEILAPEGTL-LP 68
Query: 480 VGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQ 587
VG + II DV+A + S PA + +Q
Sbjct: 69 VGAPVAIIGKQGEDVSALVETAKKSIPAKKESSITQ 104
>UniRef50_A0LSF1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Acidothermus
cellulolyticus 11B|Rep: Catalytic domain of components
of various dehydrogenase complexes - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 449
Score = 77.8 bits (183), Expect = 3e-13
Identities = 41/97 (42%), Positives = 57/97 (58%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
+V +P LS TM+ G+I W KK GD++ +GD+L EIETDKA M E + G L KIL+
Sbjct: 3 EVFMPRLSDTMQEGTITQWTKKVGDQVEKGDVLAEIETDKAVMELEAYDSGVLEKILVEP 62
Query: 462 GTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQ 572
G K VP+G + II + D ++PA P+
Sbjct: 63 G-KPVPIGTPIAIIGSGEGLQEPTGDSTAHAAPAEPK 98
>UniRef50_Q7VDH5 Cluster: Dihydrolipoamide S-acetyltransferase;
n=16; Cyanobacteria|Rep: Dihydrolipoamide
S-acetyltransferase - Prochlorococcus marinus
Length = 460
Score = 77.0 bits (181), Expect = 5e-13
Identities = 40/109 (36%), Positives = 67/109 (61%)
Frame = +3
Query: 267 LPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAK 446
+ SH + +PALS TM G IV W K+ G+K+S G+ + +E+DKA M E+ ++G+LA
Sbjct: 1 MASH-DIFMPALSSTMTEGKIVEWLKQPGEKVSRGESVLVVESDKADMDVESFQDGFLAA 59
Query: 447 ILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQDK 593
+L+P+G+ VPVG+ + +IV + ++ A + S +P + S K
Sbjct: 60 VLMPSGST-VPVGETIGLIVETEAEIPAVQAANPTKSNVSPPENLSVSK 107
>UniRef50_Q08V09 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=2;
Cystobacterineae|Rep: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase - Stigmatella
aurantiaca DW4/3-1
Length = 533
Score = 77.0 bits (181), Expect = 5e-13
Identities = 42/102 (41%), Positives = 59/102 (57%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I V +PALSPTM+ G +V W KK GDK+S G+ + E+ETDK+ + E ++G LAKIL+
Sbjct: 121 IPVLMPALSPTMKEGKVVKWLKKVGDKISSGEAIAEVETDKSNLEVEAYDDGTLAKILVD 180
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPAS 584
A + VG + I G V+ +PA P PA+
Sbjct: 181 A-DQTAQVGAPIAYIAGKGGKVSVAA-----PAPAAPSAPAA 216
Score = 69.3 bits (162), Expect = 1e-10
Identities = 36/103 (34%), Positives = 54/103 (52%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ +PALSPTM+ G +V W KK GDK+S GD + E+ETDK+ + E ++G L +I++ G
Sbjct: 5 IQMPALSPTMKEGKLVKWLKKVGDKVSSGDAIAEVETDKSNLEVEAYDDGVLLQIVVAEG 64
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQDK 593
VG + + V A + P +PA K
Sbjct: 65 DL-AQVGAPIAYVGEKGEKVEAGSKPAAPAKAEAPAQPAEAPK 106
>UniRef50_Q74Z83 Cluster: AGR323Cp; n=1; Eremothecium gossypii|Rep:
AGR323Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 402
Score = 76.6 bits (180), Expect = 7e-13
Identities = 38/98 (38%), Positives = 61/98 (62%)
Frame = +3
Query: 288 NLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGT 467
++PA+SPTME G IVSW+ K G+ GD++ E+ETDKA + E ++G LA I+ G+
Sbjct: 32 HMPAMSPTMEKGGIVSWKFKVGEPFQAGDVILEVETDKAQIDVEAQDDGKLAAIVKGDGS 91
Query: 468 KGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPA 581
K V VG+ + + ++D++A + K +S A + A
Sbjct: 92 KDVDVGETVAFLAEVEDDLSALEIPKVVTSEAPKEAEA 129
>UniRef50_O84249 Cluster: Dihydrolipoamide Acetyltransferase; n=7;
Chlamydiaceae|Rep: Dihydrolipoamide Acetyltransferase -
Chlamydia trachomatis
Length = 429
Score = 76.2 bits (179), Expect = 9e-13
Identities = 35/78 (44%), Positives = 50/78 (64%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ +P LSPTME G +V W KK GD++ GD+L EI TDKA + E+G+L +IL+ G
Sbjct: 5 LKMPKLSPTMEIGILVKWHKKAGDEIHFGDVLLEISTDKAVLEHTASEDGWLLEILVEEG 64
Query: 465 TKGVPVGKLLCIIVGDQN 518
TK P+G + + +QN
Sbjct: 65 TK-TPIGTPIAVFSTEQN 81
>UniRef50_A0H5V3 Cluster: Dihydrolipoamide S-succinyltransferase;
n=1; Chloroflexus aggregans DSM 9485|Rep:
Dihydrolipoamide S-succinyltransferase - Chloroflexus
aggregans DSM 9485
Length = 435
Score = 76.2 bits (179), Expect = 9e-13
Identities = 41/100 (41%), Positives = 59/100 (59%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
++ +P LS TM G++ W KK GD+++ GD++ EIETDKATM E E G L +IL+P
Sbjct: 3 EITMPRLSDTMSEGTVGRWLKKVGDQIAVGDIIAEIETDKATMELEAFESGVLQQILVPE 62
Query: 462 GTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPA 581
G + VP+G+ + II GD + A +S PA
Sbjct: 63 G-QTVPIGQPIAII-GDGSAPIATPPTAPPASTTPHSSPA 100
>UniRef50_Q4Q1F5 Cluster: Dihydrolipoamide acetyltransferase,
putative; n=6; Trypanosomatidae|Rep: Dihydrolipoamide
acetyltransferase, putative - Leishmania major
Length = 463
Score = 76.2 bits (179), Expect = 9e-13
Identities = 38/96 (39%), Positives = 60/96 (62%), Gaps = 3/96 (3%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFE-TPEEGYLAKILIPA 461
+ +PALSPTME G I W K+ GD + GD C IETDKA + ++ EEG+ A+++
Sbjct: 24 IPMPALSPTMEKGKITEWCKQPGDFIRPGDTFCNIETDKAVVSYDNATEEGFFARVITSP 83
Query: 462 GTKGVPVGKLLCIIVGDQNDVAA--FKDFKDDSSPA 563
G + V VG+ +C+IV ++ V + K++K ++ A
Sbjct: 84 GEETV-VGQTVCLIVDEKEGVHSDEVKNWKPEAEEA 118
>UniRef50_UPI000150A9DD Cluster: pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase family protein; n=1;
Tetrahymena thermophila SB210|Rep: pyruvate
dehydrogenase complex dihydrolipoamide acetyltransferase
family protein - Tetrahymena thermophila SB210
Length = 646
Score = 75.4 bits (177), Expect = 2e-12
Identities = 45/118 (38%), Positives = 67/118 (56%), Gaps = 8/118 (6%)
Frame = +3
Query: 258 YSSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEE-G 434
+SS P H V LPALSPTM G I +W K G K+ EGD + +++TDK ++ EE G
Sbjct: 74 FSSYPKHRLVALPALSPTMTEGKIAAWHIKVGQKIQEGDNIFDVQTDKDSVPNVYQEETG 133
Query: 435 YLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDF------KDDSSPATPQ-KPASQ 587
++AKIL+ G + +P + ++ + D+ AF +F K +P Q KPA+Q
Sbjct: 134 FVAKILVNEG-ELIPANTPVVVVCKSEADIPAFANFTVGGAQKAQEAPKQEQPKPAAQ 190
Score = 74.9 bits (176), Expect = 2e-12
Identities = 42/114 (36%), Positives = 67/114 (58%), Gaps = 7/114 (6%)
Frame = +3
Query: 261 SSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATM-GFETPEEGY 437
+S P H V LPALSPTM G I S+ K GDK++EGD + +++TDK ++ G+
Sbjct: 203 ASFPKHNVVLLPALSPTMTEGKIASFHVKVGDKVTEGDNIFDVQTDKDSVPNIYQEASGF 262
Query: 438 LAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDF------KDDSSPATPQKPA 581
+AKIL+ G + +P + ++V ++D+A F+ F K S+ + PQ+ A
Sbjct: 263 VAKILVKEG-ETIPANHPVLVVVAKKDDLAKFEQFTLNDALKKGSASSAPQEAA 315
>UniRef50_Q8YDW4 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE
COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; n=11;
Proteobacteria|Rep: DIHYDROLIPOAMIDE ACETYLTRANSFERASE
COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX - Brucella
melitensis
Length = 421
Score = 75.4 bits (177), Expect = 2e-12
Identities = 37/94 (39%), Positives = 57/94 (60%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
++V LPALS ME I W K EGD +S+GDL+ E+ETDKATM E +G + ++L+
Sbjct: 3 VEVVLPALSAGMEDAVIARWLKAEGDAVSKGDLIAEVETDKATMELEAEVDGRIGQLLVK 62
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSP 560
G + V +++ +++ + D +A F SSP
Sbjct: 63 DGAR-ANVNQVIALLLKEGEDASAMAGFAVGSSP 95
>UniRef50_A7Q7E8 Cluster: Chromosome chr18 scaffold_59, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr18 scaffold_59, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 428
Score = 75.4 bits (177), Expect = 2e-12
Identities = 40/96 (41%), Positives = 63/96 (65%), Gaps = 1/96 (1%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
++ +PALS TM G IVSW K EGDKLS+G+ + +E+DKA M ET +GYLA I++
Sbjct: 45 EIFMPALSSTMTEGKIVSWVKSEGDKLSKGESVVVVESDKADMDVETFYDGYLAAIMVEE 104
Query: 462 GTKGV-PVGKLLCIIVGDQNDVAAFKDFKDDSSPAT 566
G GV VG + ++ ++++A + K ++SP++
Sbjct: 105 G--GVAAVGSAIALLAETEDEIAEARS-KANTSPSS 137
>UniRef50_Q2S152 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvatedehydrogenase
complex; n=1; Salinibacter ruber DSM 13855|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvatedehydrogenase complex - Salinibacter ruber
(strain DSM 13855)
Length = 465
Score = 74.9 bits (176), Expect = 2e-12
Identities = 38/98 (38%), Positives = 57/98 (58%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I + +P LS TME G + +W EG+++S GD+L ++ETDKATM E +EG L K +I
Sbjct: 3 IPIEMPKLSDTMEEGVLSAWLVDEGEEVSAGDVLAQVETDKATMDLEAFDEGVLLKQVIG 62
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQ 572
G VP+G+L+ +I D++ D A P+
Sbjct: 63 EG-DAVPIGELIAVIGEAGEDISDLVDDAGGDGAAEPE 99
>UniRef50_A6EAZ4 Cluster: Dihydrolipoyllysine-residue
acetyltransferase; n=2; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue acetyltransferase -
Pedobacter sp. BAL39
Length = 549
Score = 74.5 bits (175), Expect = 3e-12
Identities = 37/101 (36%), Positives = 57/101 (56%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +P +S TM G + W KK GDK+ GD++ E+ETDKATM E+ +G + I + G
Sbjct: 5 VKMPKMSDTMTEGVMAKWHKKVGDKIKSGDVMAEVETDKATMDLESYWDGTVLYIGVEEG 64
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQ 587
K VPV ++ ++ + D A D + ++PA K A +
Sbjct: 65 -KAVPVDAIIAVVGKEGEDFQAAIDAEGGAAPAKEDKTADK 104
Score = 60.9 bits (141), Expect = 3e-08
Identities = 35/106 (33%), Positives = 50/106 (47%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +P LS TM G I W KK GD++ D+L ++ETDKATM EG L I + G
Sbjct: 136 VRMPLLSDTMTEGVIAEWHKKVGDQVKNDDILADVETDKATMEVMGYAEGTLLHIGVEKG 195
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQDKXLA 602
V ++ I+ + D++ +PA P D +A
Sbjct: 196 A-AAKVNGIIAIVGPEGTDISGI--LAQGDAPAKPAADKKSDAPVA 238
>UniRef50_Q7RFX9 Cluster: Putative dihydrolipoamide
S-acetyltransferase; n=1; Plasmodium yoelii yoelii|Rep:
Putative dihydrolipoamide S-acetyltransferase -
Plasmodium yoelii yoelii
Length = 561
Score = 74.1 bits (174), Expect = 3e-12
Identities = 36/97 (37%), Positives = 63/97 (64%)
Frame = +3
Query: 267 LPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAK 446
L S +++ +PALS TM SG IV W K G+ ++ GD++ +E+DKA M E+ +EGYL +
Sbjct: 47 LYSKVEIKMPALSSTMTSGKIVRWNKSVGEFINVGDIIMTVESDKADMDVESFDEGYLRR 106
Query: 447 ILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSS 557
LI G++ VG +L I+ ++N+ A ++ +++ +
Sbjct: 107 KLIEEGSE-ANVGDVLGILTTEENEEVANEEAENEKT 142
>UniRef50_Q38C09 Cluster: Dihydrolipoamide acetyltransferase,
putative; n=1; Trypanosoma brucei|Rep: Dihydrolipoamide
acetyltransferase, putative - Trypanosoma brucei
Length = 260
Score = 74.1 bits (174), Expect = 3e-12
Identities = 38/87 (43%), Positives = 53/87 (60%), Gaps = 1/87 (1%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGF-ETPEEGYLAKILIPA 461
+ +PALSP+M+SG IV W+KK GD + E D+ C I+TDKA + F T + GYL KI
Sbjct: 14 IYMPALSPSMDSGIIVEWKKKVGDLVKENDVFCTIQTDKAVVDFTNTFDAGYLGKIFRQN 73
Query: 462 GTKGVPVGKLLCIIVGDQNDVAAFKDF 542
G + V V + +V + DVA D+
Sbjct: 74 G-ETVAVASTIAAMVEESQDVAKLADY 99
>UniRef50_A1ZE93 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=7; Bacteria|Rep:
Pyruvate dehydrogenase complex dihydrolipoamide
acetyltransferase - Microscilla marina ATCC 23134
Length = 547
Score = 73.3 bits (172), Expect = 6e-12
Identities = 42/102 (41%), Positives = 57/102 (55%), Gaps = 2/102 (1%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +P +S TME G IVSW KK GD + EGD++ E+ETDKATM E +EG L + + G
Sbjct: 125 VTMPKMSDTMEEGVIVSWLKKVGDNIQEGDIIAEVETDKATMELEAYDEGTLLYVAVEEG 184
Query: 465 TKGVPVGKLLCIIVGDQ--NDVAAFKDFKDDSSPATPQKPAS 584
V V L+ +VG++ N A FK + KP +
Sbjct: 185 -GSVKVDGLIA-VVGEEGANYQALVDQFKAGGNAQEEAKPTT 224
Score = 72.9 bits (171), Expect = 8e-12
Identities = 41/104 (39%), Positives = 57/104 (54%), Gaps = 3/104 (2%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+++P +S TME G I W KK GD + EGD++ E+ETDKATM E+ +EG L + + G
Sbjct: 5 IHMPKMSDTMEEGVIAKWLKKVGDTIQEGDIIAEVETDKATMELESYDEGTLLYVAVEDG 64
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDFKDD---SSPATPQKPASQ 587
VPV LL I+ D + + SS AT PA +
Sbjct: 65 GV-VPVDGLLAILGAPGEDYKPLLEENGNGQASSSATESAPADE 107
>UniRef50_UPI00015B5B2E Cluster: PREDICTED: similar to
ENSANGP00000010144; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000010144 - Nasonia
vitripennis
Length = 483
Score = 72.5 bits (170), Expect = 1e-11
Identities = 52/131 (39%), Positives = 68/131 (51%), Gaps = 5/131 (3%)
Frame = +3
Query: 201 HAQN-QTVLSTPQ-WTVQMRYYSSLPS--HIK-VNLPALSPTMESGSIVSWEKKEGDKLS 365
H QN QT Q W++Q RY S S +K V +PA + ++ G V WEKKEGD++
Sbjct: 48 HVQNSQTKPHVIQSWSIQSRYIQSTSSLWEMKDVVVPAFADSISEGD-VRWEKKEGDQVK 106
Query: 366 EGDLLCEIETDKATMGFETPEEGYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFK 545
E D+LCEIETDK ++ +P G L IL G P KL I VG A K +
Sbjct: 107 EDDVLCEIETDKTSVPVPSPAAGVLKNILKKDGDTVTPGTKLCQIDVGATGGAAPSKAAE 166
Query: 546 DDSSPATPQKP 578
+ A P+ P
Sbjct: 167 TPKAEA-PKAP 176
>UniRef50_A0NRH6 Cluster: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein; n=1; Stappia aggregata IAM
12614|Rep: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein - Stappia aggregata IAM 12614
Length = 452
Score = 72.1 bits (169), Expect = 1e-11
Identities = 33/74 (44%), Positives = 50/74 (67%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
+V +PAL +SG +++W KK G+ ++ GD+L E+ETDKA M E +EGYL + A
Sbjct: 4 EVIMPALGMAQDSGQLLAWHKKPGEAVAAGDVLFEVETDKAAMEVEAQKEGYLTDVSAEA 63
Query: 462 GTKGVPVGKLLCII 503
GT VPVG+++ +I
Sbjct: 64 GT-DVPVGQVIAMI 76
Score = 65.7 bits (153), Expect = 1e-09
Identities = 34/101 (33%), Positives = 59/101 (58%)
Frame = +3
Query: 267 LPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAK 446
LP +V +P L ++G +V+W K+ G+ ++ D+L E+ETDK+T+ +G++A
Sbjct: 117 LPDGHQVIMPTLGMAQDTGLLVAWCKQPGEAVAADDILFEVETDKSTVEVNAGRDGFVAA 176
Query: 447 ILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATP 569
+L AG + VPVG+ + +I + D + K SPA+P
Sbjct: 177 LLAEAGEE-VPVGQAIAVISAQKPDKPVTR--KAGGSPASP 214
>UniRef50_Q5IX02 Cluster: Plastid pyruvate dehydrogenase complex
dihydrolipoamide S- acetyltransferase; n=1; Prototheca
wickerhamii|Rep: Plastid pyruvate dehydrogenase complex
dihydrolipoamide S- acetyltransferase - Prototheca
wickerhamii
Length = 151
Score = 71.7 bits (168), Expect = 2e-11
Identities = 48/127 (37%), Positives = 64/127 (50%), Gaps = 1/127 (0%)
Frame = +3
Query: 204 AQNQTVLSTPQWTVQMRYYSSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLC 383
A T +S P+ R L + V +PALS TM G IVSW K GDK+++G+ +
Sbjct: 21 AGRPTRVSLPRGPGGRRILRPLSAVKDVFMPALSSTMTEGKIVSWLKSPGDKVAKGESIV 80
Query: 384 EIETDKATMGFETPEEGYLAKILIPAGTKGVP-VGKLLCIIVGDQNDVAAFKDFKDDSSP 560
+E+DKA M E EG L I +P G GV VG + I + D+ A K D S+
Sbjct: 81 VVESDKADMDVEAFAEGILGCITVPEG--GVAGVGSAIAYIAETEADLEAAKAKGDSSAG 138
Query: 561 ATPQKPA 581
T PA
Sbjct: 139 TTAAAPA 145
>UniRef50_A3CFJ5 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 433
Score = 71.3 bits (167), Expect = 2e-11
Identities = 35/96 (36%), Positives = 57/96 (59%), Gaps = 3/96 (3%)
Frame = +3
Query: 312 MESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTKGVPVGKL 491
M G IVSW EGD+L++GD + +E+DKA M ET +G+LA +L+PAG + PVG
Sbjct: 1 MTEGKIVSWTASEGDRLAKGDPVVVVESDKADMDVETFHDGFLAAVLVPAG-ESAPVGSA 59
Query: 492 LCIIVGDQNDVAAFKD---FKDDSSPATPQKPASQD 590
+ ++ ++++ A + SS ++P P Q+
Sbjct: 60 IALLAESEDEIPAAQSKAASLSSSSSSSPPPPPPQE 95
>UniRef50_Q3SL16 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex dihydrolipoamide dehydrogenase E3 component;
n=2; Proteobacteria|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex dihydrolipoamide dehydrogenase E3
component - Thiobacillus denitrificans (strain ATCC
25259)
Length = 998
Score = 70.9 bits (166), Expect = 3e-11
Identities = 36/89 (40%), Positives = 49/89 (55%)
Frame = +3
Query: 273 SHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKIL 452
+H + +P LS TM G +V+WEK+ GD++ GD++ +ETDKA M E + GYLA L
Sbjct: 2 NHYAITMPQLSDTMTEGVVVTWEKQPGDRVERGDIVATVETDKAIMDVEVFKAGYLAGPL 61
Query: 453 IPAGTKGVPVGKLLCIIVGDQNDVAAFKD 539
G + VG L I DVA D
Sbjct: 62 ADVGAT-IAVGAALGYITDTAGDVAIAAD 89
Score = 62.9 bits (146), Expect = 9e-09
Identities = 42/116 (36%), Positives = 61/116 (52%), Gaps = 11/116 (9%)
Frame = +3
Query: 267 LPSHI--KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYL 440
+P H + +P LS TM G +V+WEK+ G+ + GD++ +ETDKA M E +EG+L
Sbjct: 101 IPHHAGTPIVMPQLSDTMTEGVVVTWEKQPGEAIKRGDIVATVETDKAIMDVEVFQEGFL 160
Query: 441 AKILIPAGTKGVPVGKLLCIIVGD---QND----VAAFKDFKDDSSPATP--QKPA 581
+ + G+ V VG + IV D ND ++A KD A P KPA
Sbjct: 161 SGPIADIGSV-VEVGHPMAFIVDDAAKANDTGVTISADHKVKDTHKVAPPAADKPA 215
>UniRef50_P96104 Cluster: Dihydrolipoyl transacetylase and lipoamide
dehydrogenase of the pyruvate dehydrogenase complex;
n=1; Acidithiobacillus ferrooxidans|Rep: Dihydrolipoyl
transacetylase and lipoamide dehydrogenase of the
pyruvate dehydrogenase complex - Thiobacillus
ferrooxidans (Acidithiobacillus ferrooxidans)
Length = 978
Score = 69.3 bits (162), Expect = 1e-10
Identities = 36/86 (41%), Positives = 49/86 (56%)
Frame = +3
Query: 270 PSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKI 449
P V +P LS TM G +VSWEK GD++ GD++ +ETDKA M E EGYL+
Sbjct: 108 PEGYAVKMPQLSDTMTEGVLVSWEKAPGDRIQRGDVVATVETDKAIMDVEVFREGYLSGP 167
Query: 450 LIPAGTKGVPVGKLLCIIVGDQNDVA 527
L+ A VPVG+ + +V V+
Sbjct: 168 LV-AVDAVVPVGEAIAWLVESPEQVS 192
Score = 54.0 bits (124), Expect = 4e-06
Identities = 23/51 (45%), Positives = 31/51 (60%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGY 437
+ +P LS TM G +VSWEK G ++ GD++ +ETDKA M E GY
Sbjct: 7 IKMPQLSDTMTEGVLVSWEKPAGARVERGDVVATVETDKAIMDVEVFRSGY 57
>UniRef50_Q8RD59 Cluster: Dihydrolipoamide acyltransferases; n=1;
Thermoanaerobacter tengcongensis|Rep: Dihydrolipoamide
acyltransferases - Thermoanaerobacter tengcongensis
Length = 414
Score = 68.5 bits (160), Expect = 2e-10
Identities = 35/78 (44%), Positives = 48/78 (61%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+P L TM +G +V W KKEG+K+ G+ L EIETDK TM E G L KIL+ G +
Sbjct: 7 MPKLGMTMTAGKVVRWLKKEGEKVEAGEPLLEIETDKVTMEEEAGYTGTLLKILVREGEE 66
Query: 471 GVPVGKLLCIIVGDQNDV 524
VP+ + + II G+ D+
Sbjct: 67 -VPINQPIAIIGGEGEDI 83
>UniRef50_Q9SQI8 Cluster: Dihydrolipoamide S-acetyltransferase;
n=32; cellular organisms|Rep: Dihydrolipoamide
S-acetyltransferase - Arabidopsis thaliana (Mouse-ear
cress)
Length = 480
Score = 68.5 bits (160), Expect = 2e-10
Identities = 34/85 (40%), Positives = 54/85 (63%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
++ +PALS TM G IVSW K EG+KL++G+ + +E+DKA M ET +GYLA I++
Sbjct: 57 EIFMPALSSTMTEGKIVSWIKTEGEKLAKGESVVVVESDKADMDVETFYDGYLAAIVVGE 116
Query: 462 GTKGVPVGKLLCIIVGDQNDVAAFK 536
G + PVG + ++ + ++ K
Sbjct: 117 G-ETAPVGAAIGLLAETEAEIEEAK 140
>UniRef50_A1SYC2 Cluster: Dihydrolipoamide dehydrogenase E3
component of 3 enzyme complexes; n=1; Psychromonas
ingrahamii 37|Rep: Dihydrolipoamide dehydrogenase E3
component of 3 enzyme complexes - Psychromonas
ingrahamii (strain 37)
Length = 431
Score = 68.1 bits (159), Expect = 2e-10
Identities = 37/112 (33%), Positives = 58/112 (51%), Gaps = 4/112 (3%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I++ LP + ESG I SW EGD + +GD++ E+ETDKA + E+P G L KIL+
Sbjct: 3 IEIKLPEVVSGFESGVIASWCVNEGDNIKKGDVIFEVETDKAVIEVESPGAGVLGKILVD 62
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKD----FKDDSSPATPQKPASQDKXLA 602
+ + V V ++ +I+ + D + DD++ P DK A
Sbjct: 63 SNSSPVAVDTIVGMILLENEDPSVLSGEPVITNDDANTPAPVSDVKPDKIQA 114
>UniRef50_A6Q3I4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E2 component, dihydrolipoamide
acetyltransferase; n=1; Nitratiruptor sp. SB155-2|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Nitratiruptor sp. (strain SB155-2)
Length = 408
Score = 66.9 bits (156), Expect = 5e-10
Identities = 29/74 (39%), Positives = 50/74 (67%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
K+ +P LS TM+ G ++ W KEGD + +GD++ E+E+DKA M +T ++G + K+L+
Sbjct: 4 KIVMPVLSDTMDKGKLIKWHVKEGDVVHKGDVIAEVESDKAIMEVQTFKDGVVKKLLVKE 63
Query: 462 GTKGVPVGKLLCII 503
G + VPV + + I+
Sbjct: 64 GDE-VPVKEPIAIL 76
>UniRef50_Q48TW1 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=41;
Streptococcus|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex -
Streptococcus pyogenes serotype M28
Length = 469
Score = 65.7 bits (153), Expect = 1e-09
Identities = 32/81 (39%), Positives = 49/81 (60%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
++ +P L M+ G I+ W+K+EGD ++EGD+L EI +DK M E + G L KI+ PA
Sbjct: 4 EIIMPKLGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKTNMELEAEDSGVLLKIVRPA 63
Query: 462 GTKGVPVGKLLCIIVGDQNDV 524
G VPV +++ I + V
Sbjct: 64 GDT-VPVTEVIGYIGAEGESV 83
>UniRef50_Q97Y20 Cluster: Dihydrolipoamide S-acetyltransferase,
amino-end; n=1; Sulfolobus solfataricus|Rep:
Dihydrolipoamide S-acetyltransferase, amino-end -
Sulfolobus solfataricus
Length = 211
Score = 65.7 bits (153), Expect = 1e-09
Identities = 35/80 (43%), Positives = 50/80 (62%), Gaps = 2/80 (2%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
+V +P L TM G IV W+KKEGD++ EG+ L IET+K T ++P G L KI
Sbjct: 4 EVLMPKLGLTMTKGKIVQWKKKEGDRVQEGEDLVIIETEKITTTVKSPVSGILLKIYAKE 63
Query: 462 GTKGVPVGKLLCII--VGDQ 515
G + VPVG+++ I +G+Q
Sbjct: 64 GEE-VPVGQIIAYIGEIGEQ 82
>UniRef50_A6Q9K5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E2 component, dihydrolipoamide
acetyltransferase; n=1; Sulfurovum sp. NBC37-1|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Sulfurovum sp. (strain NBC37-1)
Length = 446
Score = 65.3 bits (152), Expect = 2e-09
Identities = 37/104 (35%), Positives = 61/104 (58%), Gaps = 5/104 (4%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
KV +P LS +M+ G +V W+ + GD + GD++ E+E+DKA M + + G + ++LI A
Sbjct: 4 KVVMPRLSDSMDEGQLVEWKIRPGDVVRNGDVIAEVESDKAVMEIQIFKSGTVKELLIDA 63
Query: 462 GTKGVPVGKLLCII---VGDQNDVAAFKDFKDDSSP--ATPQKP 578
G+ VPVG + +I VG + V + K+ +S + QKP
Sbjct: 64 GST-VPVGTPMAVIDTDVGSGSSVKTEEKSKEQNSTSVSAAQKP 106
>UniRef50_Q5VGY2 Cluster: Dihydrolipoamide S-acetyltransferase; n=5;
Plasmodium|Rep: Dihydrolipoamide S-acetyltransferase -
Plasmodium falciparum
Length = 640
Score = 65.3 bits (152), Expect = 2e-09
Identities = 33/92 (35%), Positives = 54/92 (58%)
Frame = +3
Query: 273 SHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKIL 452
S I++ +PALS TM +G IV W K GD ++ GD++ +E+DKA M E +EG+L
Sbjct: 51 SKIEIKMPALSSTMTTGKIVKWNKNIGDYVNLGDIIMTVESDKADMDVEAFDEGFLRVKR 110
Query: 453 IPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKD 548
+ G + VG +L ++ ++N+ K + D
Sbjct: 111 LEDGCE-ANVGDVLGVLTTEENENMDEKKYND 141
Score = 45.6 bits (103), Expect = 0.001
Identities = 24/74 (32%), Positives = 40/74 (54%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
K+ +P + + I W K E D + + DLL +E DK+T+ E+P G + K+L+
Sbjct: 184 KIFIPFIKCKKKKAKINKWLKNENDFVKKNDLLLYVEDDKSTIEVESPYSGIIKKLLVKE 243
Query: 462 GTKGVPVGKLLCII 503
G + V + K + II
Sbjct: 244 G-QFVDLDKEVAII 256
>UniRef50_A4BP63 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=4;
Bacteria|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase -
Nitrococcus mobilis Nb-231
Length = 443
Score = 64.5 bits (150), Expect = 3e-09
Identities = 35/108 (32%), Positives = 55/108 (50%), Gaps = 4/108 (3%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I+V +PAL ++ ++V W KK GD+++ + L ++ETDK + PE+G L KIL
Sbjct: 3 IEVKVPALPESVTEATVVGWHKKPGDRVARDENLVDLETDKVVLEVPAPEDGVLGKILKD 62
Query: 459 AGTKGVPVGKLLCIIVGDQND----VAAFKDFKDDSSPATPQKPASQD 590
G V L C+ G+ N A+ K D+ +P + S D
Sbjct: 63 EGATVVADEVLACLEQGETNSQAERPASAKGEDDNRAPGPTSRQGSDD 110
>UniRef50_Q1AZ52 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Rubrobacter xylanophilus
DSM 9941|Rep: Catalytic domain of components of various
dehydrogenase complexes - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 396
Score = 63.7 bits (148), Expect = 5e-09
Identities = 30/74 (40%), Positives = 46/74 (62%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
K++LP L TME G+I+ W ++EG+ GD+L E+E++KA E G LA+I +
Sbjct: 3 KLHLPRLGQTMERGTILRWARREGEPFEVGDILYEVESEKAVNEIEAKLPGTLARITVEE 62
Query: 462 GTKGVPVGKLLCII 503
G + PVG LL ++
Sbjct: 63 GQE-CPVGTLLAVV 75
>UniRef50_A6X6G3 Cluster: Biotin/lipoyl attachment domain protein;
n=1; Ochrobactrum anthropi ATCC 49188|Rep: Biotin/lipoyl
attachment domain protein - Ochrobactrum anthropi
(strain ATCC 49188 / DSM 6882 / NCTC 12168)
Length = 443
Score = 63.7 bits (148), Expect = 5e-09
Identities = 34/84 (40%), Positives = 49/84 (58%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
++V LP + ME+G I W K+GD +++G LL EIETDKA M + P G +A I
Sbjct: 3 VEVILPKVDMDMETGQISRWYAKDGDTVTKGQLLFEIETDKAAMEVDAPASGIIADISAA 62
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAA 530
GT VPVG+ + I + + +A
Sbjct: 63 EGTV-VPVGQTVAWIYDEGEERSA 85
>UniRef50_A4AIF6 Cluster: Dihydrolipoamide acetyltransferase; n=1;
marine actinobacterium PHSC20C1|Rep: Dihydrolipoamide
acetyltransferase - marine actinobacterium PHSC20C1
Length = 425
Score = 63.7 bits (148), Expect = 5e-09
Identities = 34/101 (33%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = +3
Query: 273 SHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKIL 452
+ + + +P +S TME G++V+W K GD + G+ +CE+ TDK M E+P +G LA+I
Sbjct: 2 AELPLTMPKMSMTMEEGTMVAWLKNVGDPVRSGEPICEVATDKVDMEVESPFDGTLARI- 60
Query: 453 IPAGTKGVPVGKLLCIIVGDQNDV--AAFKDFKDDSSPATP 569
I VG + I D +D+ F + D++ A P
Sbjct: 61 IAQPDDVYAVGDTIAFITTDADDLLGGLFDEPTDEAPAAAP 101
>UniRef50_Q74AE1 Cluster: Dehydrogenase complex E2 component,
dihydrolipamide acetyltransferase; n=4; Geobacter|Rep:
Dehydrogenase complex E2 component, dihydrolipamide
acetyltransferase - Geobacter sulfurreducens
Length = 418
Score = 63.3 bits (147), Expect = 7e-09
Identities = 31/75 (41%), Positives = 47/75 (62%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ +P LS TM G +V+W+K GD++ GD++ E+ETDKATM E G LA+ + G
Sbjct: 5 ITMPKLSDTMTEGRLVAWKKGVGDRVERGDIIAEVETDKATMELEAFASGVLAEQRVKPG 64
Query: 465 TKGVPVGKLLCIIVG 509
+ V VG ++ +I G
Sbjct: 65 -ELVNVGTVIGVIGG 78
>UniRef50_A4M1P4 Cluster: Biotin/lipoyl attachment domain-containing
protein; n=1; Geobacter bemidjiensis Bem|Rep:
Biotin/lipoyl attachment domain-containing protein -
Geobacter bemidjiensis Bem
Length = 361
Score = 63.3 bits (147), Expect = 7e-09
Identities = 34/100 (34%), Positives = 55/100 (55%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
++ +P LS TM G +VSW+K+ G+ ++ G+++ E+ETDKA M E G L +I +
Sbjct: 3 EIVMPKLSDTMTEGRLVSWKKRVGETVTRGEVIAEVETDKANMELEAYVSGELLEIRVQT 62
Query: 462 GTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPA 581
G VPVG ++ +VG + A + P +PA
Sbjct: 63 GDL-VPVGTVIA-VVGKAGEKGAGATQQSAPVPHVEPEPA 100
>UniRef50_A0JS87 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Arthrobacter sp. FB24|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Arthrobacter sp. (strain FB24)
Length = 477
Score = 63.3 bits (147), Expect = 7e-09
Identities = 38/99 (38%), Positives = 54/99 (54%), Gaps = 1/99 (1%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+P+L ME G +V W K GD + GD++ ++TDK M E+ EEG +A++L+ GT
Sbjct: 1 MPSLGADMEHGKMVEWLIKPGDYVHRGDVVAVVDTDKTVMDVESFEEGVVAELLVDVGTT 60
Query: 471 GVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQ-KPAS 584
VP+G L I +D A + PA P KPAS
Sbjct: 61 -VPIGTPLARITRTPDDGAG----QAGGRPAGPHAKPAS 94
>UniRef50_A6Q8W6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E2 component, dihydrolipoamide
acetyltransferase; n=1; Sulfurovum sp. NBC37-1|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Sulfurovum sp. (strain NBC37-1)
Length = 410
Score = 62.9 bits (146), Expect = 9e-09
Identities = 27/82 (32%), Positives = 51/82 (62%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+P+L MESG+++ W+ KEG+K+ +G ++ E+E++K + E E+G + ++L+ GT
Sbjct: 6 MPSLGADMESGTLMEWKVKEGEKVKKGQVIAEVESNKGVIEVEVFEDGVVDRLLVEPGTT 65
Query: 471 GVPVGKLLCIIVGDQNDVAAFK 536
VG + +IVG+ A +
Sbjct: 66 -CDVGTPIAVIVGENETAEALE 86
>UniRef50_O31550 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of acetoin cleaving system;
n=13; Bacillus|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of acetoin cleaving system -
Bacillus subtilis
Length = 398
Score = 62.5 bits (145), Expect = 1e-08
Identities = 36/111 (32%), Positives = 56/111 (50%), Gaps = 3/111 (2%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
+KV +P L M+ G + W KK GD + +G+ + I+++K M E PE+G L I +
Sbjct: 3 VKVVMPKLGMAMKQGEVSIWNKKVGDPVEKGESIASIQSEKIEMEIEAPEKGTLIDIKVK 62
Query: 459 AGTKGVPVGKLLCIIVGDQNDVA---AFKDFKDDSSPATPQKPASQDKXLA 602
G + VP G +C I GD N+ A +D+ P Q ++K A
Sbjct: 63 EGEE-VPPGTAICYI-GDANESVQEEAGAPVAEDNMPQAVQPVKQENKPAA 111
>UniRef50_Q1NYU2 Cluster: Dihydrolipoamide acyltransferase E2
component; n=1; Candidatus Sulcia muelleri str. Hc
(Homalodisca coagulata)|Rep: Dihydrolipoamide
acyltransferase E2 component - Candidatus Sulcia
muelleri str. Hc (Homalodisca coagulata)
Length = 371
Score = 61.7 bits (143), Expect = 2e-08
Identities = 32/77 (41%), Positives = 41/77 (53%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+P LS TM G++V W KK GDK+ EGD+L EIETDKA E L I I G
Sbjct: 7 MPRLSDTMVVGTVVKWHKKIGDKILEGDILAEIETDKAIQELEAEYNSTLLYIGIKEGES 66
Query: 471 GVPVGKLLCIIVGDQND 521
+ I+G +N+
Sbjct: 67 APVNSNSVLAILGSENE 83
>UniRef50_A3SJ80 Cluster: Dihydrolipoamide acetyltransferase; n=1;
Roseovarius nubinhibens ISM|Rep: Dihydrolipoamide
acetyltransferase - Roseovarius nubinhibens ISM
Length = 443
Score = 61.7 bits (143), Expect = 2e-08
Identities = 26/61 (42%), Positives = 37/61 (60%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
K+ +P L +ME G I +W + EGD + GD+L E+ETDK + E +GYL IL+
Sbjct: 4 KITMPRLDQSMEEGRIATWTRSEGDAVKMGDVLFEVETDKVAVEVEAEADGYLHHILVAE 63
Query: 462 G 464
G
Sbjct: 64 G 64
>UniRef50_A5KCF0 Cluster: Dihydrolipoamide acetyltransferase,
putative; n=2; Plasmodium vivax|Rep: Dihydrolipoamide
acetyltransferase, putative - Plasmodium vivax
Length = 613
Score = 61.7 bits (143), Expect = 2e-08
Identities = 34/100 (34%), Positives = 55/100 (55%)
Frame = +3
Query: 273 SHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKIL 452
S I++ +PALS TM SG IV W K G+ ++ GD++ +E+DKA M E +EG+L
Sbjct: 51 SQIEIKMPALSSTMTSGKIVKWNKDVGEYVNLGDIIMTVESDKADMDVEAFDEGFLRVKH 110
Query: 453 IPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQ 572
+ G++ VG L I+ ++++ + TPQ
Sbjct: 111 MGDGSE-AKVGDTLGILTTEEDEEIEAPSDDFPAGGTTPQ 149
Score = 46.8 bits (106), Expect = 6e-04
Identities = 21/61 (34%), Positives = 34/61 (55%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
K+ LP +S I W +KE D++ + ++L +E DK+T+ E+P G + KI I
Sbjct: 187 KIFLPFVSTKRNRARISKWTRKENDRIEKDEVLFHVEDDKSTIEVESPCNGVVKKIFIEE 246
Query: 462 G 464
G
Sbjct: 247 G 247
>UniRef50_Q8VPK7 Cluster: Dihydrolipoamide dehydrogenase; n=43;
Streptococcus|Rep: Dihydrolipoamide dehydrogenase -
Streptococcus pneumoniae
Length = 567
Score = 60.9 bits (141), Expect = 3e-08
Identities = 33/104 (31%), Positives = 55/104 (52%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
++V +P M G IV W KK G+ + EG++L EI TDK +M E E+GYL IL
Sbjct: 3 LEVIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEAEEDGYLIAILKG 62
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQD 590
G + VPV +++ + ++ ++ ++SP ++ D
Sbjct: 63 DG-ETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDD 105
>UniRef50_Q3CI28 Cluster: Biotin/lipoyl attachment:Catalytic domain
of components of various dehydrogenase complexes:E3
binding; n=2; Thermoanaerobacter ethanolicus|Rep:
Biotin/lipoyl attachment:Catalytic domain of components
of various dehydrogenase complexes:E3 binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 382
Score = 60.9 bits (141), Expect = 3e-08
Identities = 34/97 (35%), Positives = 53/97 (54%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
+ V +P L TM+ G + W KK GD + +G+ + E+ TDK T E+P +G LAKIL+
Sbjct: 3 VNVVMPKLGLTMKEGRVDRWLKKVGDIVKKGEEIVEVSTDKITNVVESPADGILAKILVN 62
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATP 569
G + VPV + II + + + ++ ATP
Sbjct: 63 EG-EIVPVATPIGIITAEGEKLEEVEKSEEKFIKATP 98
>UniRef50_Q4Q822 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase,
putative; n=5; Trypanosomatidae|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase, putative - Leishmania major
Length = 389
Score = 60.5 bits (140), Expect = 5e-08
Identities = 34/105 (32%), Positives = 58/105 (55%), Gaps = 3/105 (2%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
+ +N+P ++ ++ +G +V+W KK GD ++E +++C+IE+DK + P G + KI
Sbjct: 26 LSINVPTIAESISTGKVVNWTKKVGDAVAEDEVICQIESDKLNVDVRAPANGVITKINFE 85
Query: 459 AGTKGVPVG-KLLCIIVGDQNDVAAFK--DFKDDSSPATPQKPAS 584
G V VG +L + G AA K + K D+ A P K A+
Sbjct: 86 EGA-DVEVGAQLSTMKEGPAPAAAAPKAAEVKLDAPKAEPPKAAA 129
>UniRef50_Q6AIE3 Cluster: Probable pyruvate dehydrogenase, E2
component, dihydrolipoamide acetyltransferase; n=2;
Desulfotalea psychrophila|Rep: Probable pyruvate
dehydrogenase, E2 component, dihydrolipoamide
acetyltransferase - Desulfotalea psychrophila
Length = 397
Score = 60.1 bits (139), Expect = 6e-08
Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+P+L M+ G +V W+ K GD++ GD++ E+ET K + E +G + +IL+ G K
Sbjct: 6 MPSLGADMKEGRLVEWKVKLGDQVKRGDIIAEVETAKGVIEIEVFTDGVIEQILVQRGEK 65
Query: 471 GVPVGKLLCII--VGDQNDV 524
VPVG +L I G+Q V
Sbjct: 66 -VPVGTVLATIRTAGEQGKV 84
>UniRef50_Q0LRZ3 Cluster: Dihydrolipoamide acetyltransferase, long
form; n=1; Caulobacter sp. K31|Rep: Dihydrolipoamide
acetyltransferase, long form - Caulobacter sp. K31
Length = 415
Score = 60.1 bits (139), Expect = 6e-08
Identities = 33/78 (42%), Positives = 44/78 (56%), Gaps = 1/78 (1%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG-T 467
+PALS ME +IV W K GD ++ GDL+ EIETDKAT+ E + G + +IL G T
Sbjct: 7 MPALSAGMEEATIVRWLKTVGDVIAPGDLIAEIETDKATIELEAEQTGKIGRILAAEGAT 66
Query: 468 KGVPVGKLLCIIVGDQND 521
V L + G+ D
Sbjct: 67 VAVNAEIALLLAEGEHVD 84
>UniRef50_Q8ZUR6 Cluster: Pyruvate dehydrogenase E2; n=1;
Pyrobaculum aerophilum|Rep: Pyruvate dehydrogenase E2 -
Pyrobaculum aerophilum
Length = 383
Score = 60.1 bits (139), Expect = 6e-08
Identities = 33/102 (32%), Positives = 53/102 (51%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
++ P L + G ++ W KEGD + EGD L ++ T+KAT+ P G + KIL+
Sbjct: 1 MEFKFPDLGEGLVEGEVIKWHVKEGDFVKEGDPLVDVMTEKATVTLPAPTTGRVVKILVR 60
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPAS 584
G + V VG+ LC+I + A +PA P++ A+
Sbjct: 61 EG-EVVKVGQTLCVIEPAEGPAAG----PQTEAPARPREVAA 97
>UniRef50_Q2S4D4 Cluster: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein; n=1; Salinibacter ruber DSM
13855|Rep: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein - Salinibacter ruber (strain
DSM 13855)
Length = 639
Score = 59.7 bits (138), Expect = 8e-08
Identities = 30/112 (26%), Positives = 59/112 (52%)
Frame = +3
Query: 228 TPQWTVQMRYYSSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKAT 407
+P + R+ + + + + V +P + ++ G++++W K+ GD++ + ++L EI TDK
Sbjct: 18 SPPRILTARHTTEIMAQVDVEMPKMGESITEGTVIAWHKQPGDEVEQDEILLEIGTDKVD 77
Query: 408 MGFETPEEGYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPA 563
+P+ G L + L+ G V VG ++ + D AA + DD PA
Sbjct: 78 TEVPSPKGGVLTETLVEEGDT-VEVGTIIATL---DTDTAAAEVDADDEPPA 125
Score = 48.0 bits (109), Expect = 3e-04
Identities = 32/123 (26%), Positives = 60/123 (48%), Gaps = 2/123 (1%)
Frame = +3
Query: 225 STPQWTVQMRYYSSLPS--HIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETD 398
+TP T S PS ++V +P + ++ G++V+W K G+ ++ + + EI TD
Sbjct: 153 ATPPETDSEEAASPAPSGDEVEVVMPKMGESITEGTVVAWYKDIGEAVAIDETILEIGTD 212
Query: 399 KATMGFETPEEGYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKP 578
K +P EG L + L+ G + V VG ++ ++ + + D+ P T Q+
Sbjct: 213 KVDTEVPSPAEGVLTEKLVEEG-ETVEVGTVVALLASEAEAGSVEPPASDE--PDTTQET 269
Query: 579 ASQ 587
A +
Sbjct: 270 APE 272
>UniRef50_Q59299 Cluster: Dihydrolipoyl dehydrogenase; n=6;
Clostridium|Rep: Dihydrolipoyl dehydrogenase -
Clostridium magnum
Length = 578
Score = 59.7 bits (138), Expect = 8e-08
Identities = 32/103 (31%), Positives = 54/103 (52%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +P L TM G++V+W+K EGD++ G++L E+ TDK T E+ +EG + K+L+ G
Sbjct: 5 VVMPKLGLTMTEGTLVTWKKAEGDQVKVGEILFEVSTDKLTNEVESSDEGIVRKLLVNEG 64
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQDK 593
V + II D+++ + + S + Q K
Sbjct: 65 DV-VECLNPVAIIGSADEDISSLLNGSSEGSGSAEQSDTKAPK 106
>UniRef50_A0K281 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Arthrobacter|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Arthrobacter sp. (strain FB24)
Length = 527
Score = 59.3 bits (137), Expect = 1e-07
Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 3/104 (2%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
K NLP + + IVSW K GD ++ D+LCEIET K+ + +P G + ++L+P
Sbjct: 5 KFNLPDVGEGLTEAEIVSWNVKPGDSVAINDILCEIETAKSLVELPSPFAGTVTELLVPV 64
Query: 462 GTK---GVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPAS 584
G G P+ + + GD A ++ TP P +
Sbjct: 65 GVTVDVGTPIISVSDAVSGDPTPADAPVPVAPAAAAQTPAAPTA 108
>UniRef50_A6UDY3 Cluster: Biotin/lipoyl attachment domain-containing
protein; n=1; Sinorhizobium medicae WSM419|Rep:
Biotin/lipoyl attachment domain-containing protein -
Sinorhizobium medicae WSM419
Length = 437
Score = 58.8 bits (136), Expect = 1e-07
Identities = 37/104 (35%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ +P L TME G IV W K GD GD + EIETDK F +G L ++L+ G
Sbjct: 6 LKMPRLGETMEEGKIVGWLIKPGDSFRRGDPIIEIETDKTIAEFPALGDGRLEEVLVEIG 65
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDF-KDDSSPATPQKPASQDK 593
+ VGK L + D+ + D+ +D S A P+ A+ K
Sbjct: 66 DM-IEVGKPLARV-----DIVSGPDWTAEDGSAAEPETEAAVTK 103
>UniRef50_A5MZI5 Cluster: PdhC; n=6; Clostridium|Rep: PdhC -
Clostridium kluyveri DSM 555
Length = 444
Score = 58.4 bits (135), Expect = 2e-07
Identities = 29/80 (36%), Positives = 45/80 (56%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+P L TM G I +W K EGD++ +G++L ++ TDK T E E G L KIL+ G
Sbjct: 7 MPKLGLTMTEGEIETWHKSEGDEVKKGEVLFDVTTDKLTNEVEAKESGILRKILVKEGET 66
Query: 471 GVPVGKLLCIIVGDQNDVAA 530
+ + + II G D+++
Sbjct: 67 AKCL-EPVAIIAGADEDISS 85
>UniRef50_A4FIZ9 Cluster: Acetoin dehydrogenase, dihydrolipoamide
acetyltransferase component; n=1; Saccharopolyspora
erythraea NRRL 2338|Rep: Acetoin dehydrogenase,
dihydrolipoamide acetyltransferase component -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 371
Score = 58.4 bits (135), Expect = 2e-07
Identities = 28/74 (37%), Positives = 43/74 (58%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
+V +P +M +G I W EGD +S+GD L EI+TDK E+ EG L +I++ A
Sbjct: 8 RVTMPKWGLSMTTGKITDWWASEGDDVSDGDDLAEIDTDKIAGTLESTGEGVLRRIVVAA 67
Query: 462 GTKGVPVGKLLCII 503
G+ PVG + ++
Sbjct: 68 GS-DAPVGATIAVV 80
>UniRef50_A3VK82 Cluster: Putative uncharacterized protein; n=1;
Rhodobacterales bacterium HTCC2654|Rep: Putative
uncharacterized protein - Rhodobacterales bacterium
HTCC2654
Length = 472
Score = 58.4 bits (135), Expect = 2e-07
Identities = 31/92 (33%), Positives = 44/92 (47%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ LP M G++ W EGD +G L ++ETDK E + G L +I++P G
Sbjct: 7 ITLPKWGLEMSEGTVTGWHLAEGDSAEKGAELVDVETDKIVNVVELDQAGTLRRIVVPEG 66
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSP 560
+ VPVG L+ + D AA F D P
Sbjct: 67 -ETVPVGTLIAVFADASVDDAAIDGFIADYKP 97
>UniRef50_Q8RBW8 Cluster: Dihydrolipoamide acyltransferases; n=1;
Thermoanaerobacter tengcongensis|Rep: Dihydrolipoamide
acyltransferases - Thermoanaerobacter tengcongensis
Length = 399
Score = 58.0 bits (134), Expect = 2e-07
Identities = 29/69 (42%), Positives = 41/69 (59%)
Frame = +3
Query: 321 GSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTKGVPVGKLLCI 500
G +V+W K EG + G+LL E++ +KA + + P G L KIL P G V VG+LLC+
Sbjct: 17 GFVVNWFKDEGQPVQAGELLLEVQFEKAAIELQAPVSGILTKILCPQG-HVVKVGQLLCL 75
Query: 501 IVGDQNDVA 527
I +VA
Sbjct: 76 IEEKSTEVA 84
>UniRef50_A0Z5N6 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
marine gamma proteobacterium HTCC2080|Rep: Pyruvate
dehydrogenase complex, E2 component, dihydrolipoamide
acetyltransferase - marine gamma proteobacterium
HTCC2080
Length = 390
Score = 58.0 bits (134), Expect = 2e-07
Identities = 35/102 (34%), Positives = 52/102 (50%), Gaps = 2/102 (1%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +P M G IV+W EG++++ G L +IETDK FE G L KIL+P G
Sbjct: 8 VTIPKWGIEMTHGRIVAWRYSEGEQIAAGAELVDIETDKIVNSFEARVAGSLVKILVPEG 67
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDF--KDDSSPATPQKPAS 584
+ +PVG L+ ++ A + F K + A +PA+
Sbjct: 68 EE-LPVGTLIGVLAMTDFQPAELEAFIAKQKLAEAAVPEPAT 108
>UniRef50_Q98FT5 Cluster: Dihydrolipoamide acetyltransferase
homoserine dehydrogenase; n=23; Alphaproteobacteria|Rep:
Dihydrolipoamide acetyltransferase homoserine
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 454
Score = 57.6 bits (133), Expect = 3e-07
Identities = 34/96 (35%), Positives = 49/96 (51%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
+V LP + M +G I W +EG ++ +GD+L EIETDKA M + P G L +
Sbjct: 4 EVILPKVDMDMATGQISRWFAEEGARVKKGDVLFEIETDKAAMEIDAPASGVLRDVSGKE 63
Query: 462 GTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATP 569
G +PVG + I D A K D++P +P
Sbjct: 64 GV-DIPVGAPVAWIYADDEAYGA----KQDAAPISP 94
>UniRef50_Q0LND0 Cluster: Dihydrolipoamide S-succinyltransferase;
n=1; Herpetosiphon aurantiacus ATCC 23779|Rep:
Dihydrolipoamide S-succinyltransferase - Herpetosiphon
aurantiacus ATCC 23779
Length = 442
Score = 57.6 bits (133), Expect = 3e-07
Identities = 27/68 (39%), Positives = 41/68 (60%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
K+ +P + M G++ W KK GD++S G+ + E+ETDK T+ E E G + K L+
Sbjct: 4 KLEMPKMGYDMVEGTLAKWLKKPGDEVSRGEPIAEVETDKVTIEIEAFEAGTILKFLVNE 63
Query: 462 GTKGVPVG 485
G + VPVG
Sbjct: 64 G-ETVPVG 70
>UniRef50_A4WK39 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Pyrobaculum|Rep: Catalytic
domain of components of various dehydrogenase complexes
- Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Length = 408
Score = 57.6 bits (133), Expect = 3e-07
Identities = 37/102 (36%), Positives = 52/102 (50%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I+ P L + G IV W KEGD + EGD L ++ T+KA + P G + KI
Sbjct: 2 IEFKFPDLGEGLVEGEIVKWHVKEGDFVKEGDPLVDVMTEKANVTLPAPATGKVVKIFAK 61
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPAS 584
G + V VG++LC+I +VAA ++SP P AS
Sbjct: 62 EG-EIVKVGQVLCVI----EEVAA-----QEASPKAPAAEAS 93
>UniRef50_Q4RLV1 Cluster: Chromosome 10 SCAF15019, whole genome
shotgun sequence; n=5; Bilateria|Rep: Chromosome 10
SCAF15019, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 461
Score = 57.2 bits (132), Expect = 4e-07
Identities = 28/74 (37%), Positives = 45/74 (60%), Gaps = 3/74 (4%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
+ V PA + ++ G V WEK GD ++E +++CEIETDK ++ +P G + ++L+P
Sbjct: 71 VTVKTPAFAESVTEGD-VRWEKAVGDTVTEDEVVCEIETDKTSVQVPSPAAGVIEELLVP 129
Query: 459 AGTK---GVPVGKL 491
G K G P+ KL
Sbjct: 130 DGGKVEGGTPLFKL 143
>UniRef50_A5UU13 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=4; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Roseiflexus sp. RS-1
Length = 459
Score = 56.8 bits (131), Expect = 6e-07
Identities = 28/81 (34%), Positives = 44/81 (54%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ +P + M+ G+IV W KK GD + G+ + EIETDK T+ E E G L +I++ G
Sbjct: 4 ITMPKMGFDMQEGTIVRWLKKPGDAVRRGEPIAEIETDKVTIEIEAFESGTLTEIVVQEG 63
Query: 465 TKGVPVGKLLCIIVGDQNDVA 527
+ PV ++ + G A
Sbjct: 64 -QSAPVNAVIARLDGGNGSQA 83
>UniRef50_Q553V8 Cluster: Dihydrolipoamide S-succinyltransferase;
n=2; Dictyostelium discoideum|Rep: Dihydrolipoamide
S-succinyltransferase - Dictyostelium discoideum AX4
Length = 439
Score = 56.8 bits (131), Expect = 6e-07
Identities = 32/110 (29%), Positives = 57/110 (51%)
Frame = +3
Query: 252 RYYSSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEE 431
R+YSS + + + +P++ ++ G+IV+W K GD + +++C IETDK T+ P
Sbjct: 66 RFYSSA-NDVVIKVPSMGDSISEGTIVAWTKNVGDSVRVDEVVCSIETDKVTIDINAPVS 124
Query: 432 GYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPA 581
G + ++ G + V VG L I + +VAA + + P+ A
Sbjct: 125 GTIVELFAKEG-ENVTVGNDLYKIA--KGEVAAAPKVEAPKAAEAPKAAA 171
>UniRef50_Q65MC9 Cluster: AcoC; n=1; Bacillus licheniformis ATCC
14580|Rep: AcoC - Bacillus licheniformis (strain DSM 13
/ ATCC 14580)
Length = 377
Score = 56.4 bits (130), Expect = 7e-07
Identities = 26/81 (32%), Positives = 49/81 (60%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
++V +P L +M+ G++ W KK G+ + +G+ + I ++K M E+P G + I +
Sbjct: 3 VEVVMPKLGMSMKEGTVSVWNKKVGEAVEKGESIASINSEKIEMEIESPANGTVLDIQVS 62
Query: 459 AGTKGVPVGKLLCIIVGDQND 521
G +GVP G ++C I G++N+
Sbjct: 63 EG-EGVPPGTVICRI-GNENE 81
>UniRef50_A7BC27 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 448
Score = 56.0 bits (129), Expect = 1e-06
Identities = 39/101 (38%), Positives = 53/101 (52%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +P L ++ES IV W EGD +S L IETDK+TM + EG + K+L G
Sbjct: 5 VVMPQLGNSVESCIIVEWMIAEGDTVSVDQTLASIETDKSTMEVPSTAEGTVLKLLWEEG 64
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQ 587
+ VPV L IIVG+ + + D++PA PA Q
Sbjct: 65 DE-VPVKDPL-IIVGEPGEDISGLVPGGDAAPAEADAPAEQ 103
>UniRef50_A4XEQ9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Sphingomonadaceae|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Novosphingobium aromaticivorans (strain DSM
12444)
Length = 480
Score = 56.0 bits (129), Expect = 1e-06
Identities = 30/91 (32%), Positives = 42/91 (46%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+P M G+I W KEG+ ++G +LC IET K T E + L ++L PA +
Sbjct: 9 MPKWGIEMTEGTIAEWMVKEGEAFNKGQVLCLIETAKITNEVEAEYDAVLKRLLTPASDE 68
Query: 471 GVPVGKLLCIIVGDQNDVAAFKDFKDDSSPA 563
PVG LL + A +F PA
Sbjct: 69 AHPVGALLAVFADADTTDAEVDEFIAGFKPA 99
>UniRef50_Q6FDE9 Cluster: Dihydrolipoamide acetyltransferase; n=3;
Gammaproteobacteria|Rep: Dihydrolipoamide
acetyltransferase - Acinetobacter sp. (strain ADP1)
Length = 513
Score = 55.6 bits (128), Expect = 1e-06
Identities = 31/77 (40%), Positives = 43/77 (55%), Gaps = 1/77 (1%)
Frame = +3
Query: 273 SHIK-VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKI 449
S IK + +P +ME G++ W +EG +GD +CEIET K E P +G L +I
Sbjct: 2 SEIKTLEIPKWGLSMEEGTVAQWLIEEGTSFKKGDEICEIETTKIVNVLEAPFDGTLRQI 61
Query: 450 LIPAGTKGVPVGKLLCI 500
L AG +PVG L+ I
Sbjct: 62 LAHAGDT-LPVGGLIAI 77
>UniRef50_Q39FN4 Cluster: Alpha/beta hydrolase; n=10; Burkholderia
cepacia complex|Rep: Alpha/beta hydrolase - Burkholderia
sp. (strain 383) (Burkholderia cepacia (strain ATCC
17760/ NCIB 9086 / R18194))
Length = 371
Score = 55.6 bits (128), Expect = 1e-06
Identities = 32/104 (30%), Positives = 56/104 (53%), Gaps = 4/104 (3%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ +P +ME G + W K G+++++GD + ++ETDK + G E +G L + + G
Sbjct: 6 ITMPKWGLSMEQGQVNGWLKALGERVTKGDEVLDVETDKISSGVECAFDGTLRRQVAQEG 65
Query: 465 TKGVPVGKLLCII-VGDQNDV---AAFKDFKDDSSPATPQKPAS 584
+ +PVG LL ++ D +D AA DF+ D P+ A+
Sbjct: 66 -ETLPVGALLGVVAAADASDADIDAAIADFQRDFVPSAASDEAA 108
>UniRef50_UPI00006DB259 Cluster: COG0508: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzymes; n=1; Burkholderia
dolosa AUO158|Rep: COG0508: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzymes - Burkholderia
dolosa AUO158
Length = 124
Score = 55.2 bits (127), Expect = 2e-06
Identities = 27/80 (33%), Positives = 46/80 (57%), Gaps = 1/80 (1%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ +P +ME G + W K G+++++GD + ++ETDK + G E P +G L + + G
Sbjct: 6 ITMPKWGLSMEQGQVNGWLKAVGERVTKGDEVLDVETDKISSGVECPFDGTLRRQIAQEG 65
Query: 465 TKGVPVGKLLCIIV-GDQND 521
+PVG LL ++ D ND
Sbjct: 66 DT-LPVGALLGVVADADTND 84
>UniRef50_UPI00006A2AB5 Cluster: UPI00006A2AB5 related cluster; n=2;
Xenopus tropicalis|Rep: UPI00006A2AB5 UniRef100 entry -
Xenopus tropicalis
Length = 597
Score = 55.2 bits (127), Expect = 2e-06
Identities = 29/83 (34%), Positives = 46/83 (55%), Gaps = 2/83 (2%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ +P ++ ++V W KKEG+ ++ GD L E+ETDKA + G + + L+PAG
Sbjct: 5 LRMPEVAANATHATLVRWAKKEGESIAVGDCLAEVETDKAIVEINADSAGVMGQWLVPAG 64
Query: 465 TKGVPVGKLLCII--VGDQNDVA 527
V VG L ++ G+ DVA
Sbjct: 65 -HVVEVGAPLAVLRAEGEAADVA 86
>UniRef50_Q54TR7 Cluster: Dihydrolipoyl transacylase; n=1;
Dictyostelium discoideum AX4|Rep: Dihydrolipoyl
transacylase - Dictyostelium discoideum AX4
Length = 517
Score = 55.2 bits (127), Expect = 2e-06
Identities = 50/181 (27%), Positives = 83/181 (45%), Gaps = 9/181 (4%)
Frame = +3
Query: 66 LIMLRTIVLRNQILSDGLKK--AIRSNITRCI-------STELAKRKVTNKLLEHAQNQT 218
+I R I+ +++ LS+ L+K +R T CI S + NK + N
Sbjct: 1 MISTRQILSKSKRLSNVLQKQQVVRGISTSCIFSNNSNNSNSNSNINSNNKSITRLSNSI 60
Query: 219 VLSTPQWTVQMRYYSSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETD 398
+ + V R YSS IK NL + + ++ W KEGD++ E D LCE+++D
Sbjct: 61 NIKSNFEKVIFRNYSSA---IKFNLADVGEGIAECEVLVWYVKEGDQIKEFDKLCEVQSD 117
Query: 399 KATMGFETPEEGYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKP 578
KAT+ + +G + KI G VG+ L + + ++ +A K +S T P
Sbjct: 118 KATVEITSRYDGIVTKICHKIGDM-AKVGEPL-VEITPESSIAEIKLNAGPASQVTVTPP 175
Query: 579 A 581
+
Sbjct: 176 S 176
>UniRef50_Q0W153 Cluster: Pyruvate dehydrogenase complex E2,
dihydrolipoamide acetyltransferase; n=1; uncultured
methanogenic archaeon RC-I|Rep: Pyruvate dehydrogenase
complex E2, dihydrolipoamide acetyltransferase -
Uncultured methanogenic archaeon RC-I
Length = 428
Score = 55.2 bits (127), Expect = 2e-06
Identities = 28/71 (39%), Positives = 38/71 (53%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
LP L + SG I W K+GDK+ E D + E+ETDKA + P G + I G
Sbjct: 7 LPDLGEGITSGEIKKWNVKKGDKVEEDDPIAEVETDKAVVELPAPVSGTVEDIKFKEGDM 66
Query: 471 GVPVGKLLCII 503
VPVG ++ +I
Sbjct: 67 -VPVGSVIAVI 76
>UniRef50_UPI00015552BA Cluster: PREDICTED: similar to
dihydrolipoamide S-succinyltransferase (E2 component of
2-oxo-glutarate complex), partial; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to dihydrolipoamide
S-succinyltransferase (E2 component of 2-oxo-glutarate
complex), partial - Ornithorhynchus anatinus
Length = 306
Score = 54.8 bits (126), Expect = 2e-06
Identities = 24/64 (37%), Positives = 39/64 (60%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
+ V PA + ++ G V WEK GD ++E +++CEIETDK ++ +P G + +L+P
Sbjct: 127 VTVKTPAFAESVTEGD-VRWEKAVGDAVAEDEVVCEIETDKTSVQVPSPSAGVIEALLVP 185
Query: 459 AGTK 470
G K
Sbjct: 186 DGGK 189
>UniRef50_Q18CC1 Cluster: E3 component of acetoin dehydrogenase
enzyme system; n=2; Clostridium difficile|Rep: E3
component of acetoin dehydrogenase enzyme system -
Clostridium difficile (strain 630)
Length = 576
Score = 54.8 bits (126), Expect = 2e-06
Identities = 28/75 (37%), Positives = 45/75 (60%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
++V +P ME G+IVSW K+EG+++ G+ + EI TDK M E+ EG LA I+
Sbjct: 3 VEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKVNMEIESEGEGTLAVIIHK 62
Query: 459 AGTKGVPVGKLLCII 503
+ +PV ++ +I
Sbjct: 63 EEGEVLPVFTVIGVI 77
>UniRef50_P36957 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor; n=48;
Fungi/Metazoa group|Rep: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor - Homo
sapiens (Human)
Length = 453
Score = 54.8 bits (126), Expect = 2e-06
Identities = 24/64 (37%), Positives = 39/64 (60%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
+ V PA + ++ G V WEK GD ++E +++CEIETDK ++ +P G + +L+P
Sbjct: 71 VTVKTPAFAESVTEGD-VRWEKAVGDTVAEDEVVCEIETDKTSVQVPSPANGVIEALLVP 129
Query: 459 AGTK 470
G K
Sbjct: 130 DGGK 133
>UniRef50_Q89AJ6 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=15; Proteobacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Buchnera aphidicola subsp. Baizongia pistaciae
Length = 410
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/85 (31%), Positives = 47/85 (55%), Gaps = 3/85 (3%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I + +P L ++ +I+ W KK+GDK+ E +L +IETDK + +P +G L I+
Sbjct: 4 INIFIPDLPESVTDATIIKWHKKKGDKVQEDTILVDIETDKVILEIPSPSDGILNSIIAD 63
Query: 459 AGTKGVP---VGKLLCIIVGDQNDV 524
G +P +G LL I + ++ +
Sbjct: 64 KGKIVLPGQVIGTLLKIGIKNEEKI 88
>UniRef50_Q1M9D5 Cluster: Putative biotin-binding protein; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
biotin-binding protein - Rhizobium leguminosarum bv.
viciae (strain 3841)
Length = 78
Score = 54.4 bits (125), Expect = 3e-06
Identities = 32/75 (42%), Positives = 39/75 (52%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I + +P L ++ I W K EGD ++EG+ L I T K TM E P G L KILIP
Sbjct: 3 IPIIMPNLGNEIDEAQIDEWFKTEGDMVTEGEQLVLITTPKVTMEIEAPATGILKKILIP 62
Query: 459 AGTKGVPVGKLLCII 503
A VG L II
Sbjct: 63 ADELAA-VGSTLGII 76
>UniRef50_Q088Y5 Cluster: Biotin/lipoyl attachment domain-containing
protein; n=1; Shewanella frigidimarina NCIMB 400|Rep:
Biotin/lipoyl attachment domain-containing protein -
Shewanella frigidimarina (strain NCIMB 400)
Length = 99
Score = 54.4 bits (125), Expect = 3e-06
Identities = 25/86 (29%), Positives = 46/86 (53%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ +P TME GS+ +W + G ++ GD + +IET+K T +E+P G + + G
Sbjct: 8 ITMPKFGLTMEKGSVSAWHVEVGKTVAVGDEIADIETEKVTSAYESPIAGTWRRSVASVG 67
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDF 542
+ +P+G L+ ++ + D A F
Sbjct: 68 DE-LPIGSLIGVMASPEIDDAQIDSF 92
>UniRef50_Q97CK2 Cluster: Pyruvate dehydrogenase E2 /
dihydrolipoamide acetyltransferase; n=3;
Thermoplasma|Rep: Pyruvate dehydrogenase E2 /
dihydrolipoamide acetyltransferase - Thermoplasma
volcanium
Length = 400
Score = 54.4 bits (125), Expect = 3e-06
Identities = 32/99 (32%), Positives = 51/99 (51%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
LP + + G IV W+ EGD++ + L E+ TDK T+ +P G ++KIL G +
Sbjct: 6 LPDIGEGVTEGEIVKWDVAEGDEVKKDQDLVEVMTDKVTVKIPSPVNGKISKILYKEG-Q 64
Query: 471 GVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQ 587
VPVG L I D + + + ++ + PQ A+Q
Sbjct: 65 VVPVGSTLVQI--DTGEETSQQTMAEEHAELKPQTTAAQ 101
>UniRef50_Q4UKI7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=135; root|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Rickettsia felis (Rickettsia azadi)
Length = 401
Score = 54.4 bits (125), Expect = 3e-06
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 7/115 (6%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
+K+ +P+L ++ +I W KKEGD + +LL EIET+K T+ P +G + KI
Sbjct: 3 VKIIVPSLGESVTEATIAKWYKKEGDPVKTDELLLEIETEKVTLEVNAPCDGTIGKISKT 62
Query: 459 AGTK---GVPVGKL----LCIIVGDQNDVAAFKDFKDDSSPATPQKPASQDKXLA 602
G G +G++ G N+ A + +S +KPA + LA
Sbjct: 63 DGANVAVGEEIGEINEGAAANTAGTNNESAKAQAVTQPTSEKPVEKPAVVNNILA 117
>UniRef50_A6GG26 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvatedehydrogenase
complex; n=1; Plesiocystis pacifica SIR-1|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvatedehydrogenase complex - Plesiocystis pacifica
SIR-1
Length = 436
Score = 54.0 bits (124), Expect = 4e-06
Identities = 24/64 (37%), Positives = 40/64 (62%)
Frame = +3
Query: 312 MESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTKGVPVGKL 491
ME G + +W GDK+ G ++ EIETDKATM FE+ + GY+ ++ G + +P+G
Sbjct: 1 MEEGVVANWRIALGDKVKRGQVIAEIETDKATMEFESFDSGYVLLLVAEEG-ETLPLGAP 59
Query: 492 LCII 503
+ ++
Sbjct: 60 IAVL 63
>UniRef50_Q7WED2 Cluster: Probable 2-oxo acid dehydrogenases
acyltransferase; n=2; Bacteria|Rep: Probable 2-oxo acid
dehydrogenases acyltransferase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 416
Score = 53.6 bits (123), Expect = 5e-06
Identities = 32/99 (32%), Positives = 47/99 (47%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+P L TM G ++ W G ++ GD L +ETDK +G LA+IL+ AG +
Sbjct: 9 MPKLGLTMTEGMLIEWSVTSGAEVKAGDSLFVVETDKVANEIVAQADGTLAEILVAAG-E 67
Query: 471 GVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQ 587
VPVG ++ G D +P PQ PA++
Sbjct: 68 TVPVGTVVARWTGPGQGADDLADAPPAPAPQPPQ-PAAE 105
>UniRef50_A5CEI9 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=1;
Orientia tsutsugamushi Boryong|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase - Orientia tsutsugamushi (strain
Boryong) (Rickettsia tsutsugamushi)
Length = 425
Score = 53.6 bits (123), Expect = 5e-06
Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 2/89 (2%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
LP+L ++ +G+I W KKEGD ++ + + E+E+DK + G + KIL G
Sbjct: 12 LPSLGESVSTGTISKWHKKEGDIVALDEKIVEVESDKVGIDINANVPGKITKILKNEG-D 70
Query: 471 GVPVGKLLCIIVGD--QNDVAAFKDFKDD 551
V VG+++C+I D Q ++ + K + D
Sbjct: 71 NVEVGEVICVIRSDVLQKEIHSSKSSEID 99
>UniRef50_Q82SG4 Cluster: SucB; dihydrolipoamide succinyltransferase
(Component of 2- oxoglutarate dehydrogenase complex)
protein; n=4; Bacteria|Rep: SucB; dihydrolipoamide
succinyltransferase (Component of 2- oxoglutarate
dehydrogenase complex) protein - Nitrosomonas europaea
Length = 425
Score = 53.2 bits (122), Expect = 7e-06
Identities = 21/58 (36%), Positives = 38/58 (65%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKIL 452
I+V +PALS ++ ++++W K+ G+ + G+ L +IETDK + P+ G LA+I+
Sbjct: 3 IEVKVPALSESVAEATLINWHKQPGEYVERGENLIDIETDKVVLELPAPQSGILAEII 60
>UniRef50_Q12FH2 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=3; Proteobacteria|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 420
Score = 53.2 bits (122), Expect = 7e-06
Identities = 26/84 (30%), Positives = 48/84 (57%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I+ LPAL M+ G+++ W + GD + G ++ ++T KA + E ++G + ++ +
Sbjct: 2 IEFKLPALGADMDEGTLLKWHVQPGDAVKRGQVVAVVDTSKAAVDVEIWQDGVMTELRVQ 61
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAA 530
G K VPVG +L ++ +VAA
Sbjct: 62 PGEK-VPVGTVLARLLA-PGEVAA 83
>UniRef50_A4XHV3 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Caldicellulosiruptor
saccharolyticus DSM 8903|Rep: Catalytic domain of
components of various dehydrogenase complexes -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 460
Score = 53.2 bits (122), Expect = 7e-06
Identities = 35/99 (35%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +P T+ES I W KK+G+K+ GDLL ETDKA+ E G L I G
Sbjct: 5 VIMPKQGQTVESCIITKWHKKKGEKVEVGDLLFSYETDKASFDEEAKVSGILLDIFFEEG 64
Query: 465 TKGVPVGKLLCIIVGDQNDVA-AFKDFKDDSSPATPQKP 578
+ VPV + +I G +N+ A F K + + + P
Sbjct: 65 EE-VPVLTNVAVI-GQENESADIFNPKKGTDATISAESP 101
>UniRef50_A1WK19 Cluster: Alpha/beta hydrolase fold; n=1;
Verminephrobacter eiseniae EF01-2|Rep: Alpha/beta
hydrolase fold - Verminephrobacter eiseniae (strain
EF01-2)
Length = 440
Score = 53.2 bits (122), Expect = 7e-06
Identities = 29/74 (39%), Positives = 41/74 (55%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
+V LP + M G I W K GD++ +G +L +IETDKATM E P G + I
Sbjct: 4 EVILPRVDMDMAEGKIACWYVKNGDQVRKGQVLFDIETDKATMEVEAPASGVIDSIDGAI 63
Query: 462 GTKGVPVGKLLCII 503
G +PVG+++ I
Sbjct: 64 GVT-MPVGQVVAWI 76
>UniRef50_A0Z3Y6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide acyltransferase (E2)
component, and related enzyme; n=1; marine gamma
proteobacterium HTCC2080|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzyme - marine gamma
proteobacterium HTCC2080
Length = 388
Score = 53.2 bits (122), Expect = 7e-06
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 11/112 (9%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ +P M G+I +W K +GD +++GD + E+E+DK +E P +G L ++L G
Sbjct: 7 IAVPKWGIEMVEGTITTWNKSQGDAVAKGDEVFEMESDKIVNVWEAPVDGVLRRVLAEPG 66
Query: 465 TKGVPVGKLLCIIVG---DQNDVAAF------KDFKDDSSPAT--PQKPASQ 587
PVG LL +I D+ F D K+ + AT P KP +Q
Sbjct: 67 -DAHPVGALLGVIAPAAVSDGDIDTFIAGYAGDDAKEAPAQATAEPAKPVAQ 117
>UniRef50_Q4UGK1 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex,
mitochondrial, putative; n=2; Theileria|Rep:
Dihydrolipoamide succinyltransferase component of
2-oxoglutarate dehydrogenase complex, mitochondrial,
putative - Theileria annulata
Length = 457
Score = 53.2 bits (122), Expect = 7e-06
Identities = 40/117 (34%), Positives = 59/117 (50%), Gaps = 5/117 (4%)
Frame = +3
Query: 252 RYYSSLPSHIKV-NLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPE 428
RY+S IKV N+P L ++ G++ W GD L+ DL+ +ETDK ++ +P
Sbjct: 66 RYFSK---DIKVINVPTLGDSISEGTLTKWAVSVGDYLNVDDLIAVVETDKVSVDVNSPF 122
Query: 429 EGYLAKILIPAGTKGVPVGKLLCII--VGDQNDVAAFKDFKDDSSP--ATPQKPASQ 587
G L K G + VGK L I G ++ A K K D+ P +TP KP ++
Sbjct: 123 SGVLTKTFSNTGDT-ILVGKPLVEIDLAGKPSEKAPEK--KPDAKPPASTPTKPETK 176
>UniRef50_Q59695 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of acetoin cleaving system;
n=7; Bacteria|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of acetoin cleaving system -
Pseudomonas putida
Length = 370
Score = 53.2 bits (122), Expect = 7e-06
Identities = 24/74 (32%), Positives = 44/74 (59%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ +P +M G + +W K+EGD++++GD + ++ETDK + E P G L + +
Sbjct: 7 LTMPKWGLSMTEGRVDAWLKQEGDEINKGDEVLDVETDKISSSVEAPFSGVLRR-QVAKP 65
Query: 465 TKGVPVGKLLCIIV 506
+ +PVG LL ++V
Sbjct: 66 DETLPVGALLAVVV 79
>UniRef50_Q9KES1 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Bacillus halodurans|Rep: Dihydrolipoamide
S-acetyltransferase - Bacillus halodurans
Length = 436
Score = 52.8 bits (121), Expect = 9e-06
Identities = 24/55 (43%), Positives = 36/55 (65%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAK 446
++ +P LS TM+ G+++ W K+EGD++ G+ L EI TDK + E EEG L K
Sbjct: 4 EIFMPKLSSTMQEGTLLQWFKEEGDRVEVGEPLFEIMTDKINIEVEAYEEGTLLK 58
>UniRef50_A4A156 Cluster: Pyruvate dehydrogenase, E2 component,
dihydrolipoamideacetyltransferase; n=2;
Planctomycetaceae|Rep: Pyruvate dehydrogenase, E2
component, dihydrolipoamideacetyltransferase -
Blastopirellula marina DSM 3645
Length = 472
Score = 52.4 bits (120), Expect = 1e-05
Identities = 36/105 (34%), Positives = 57/105 (54%), Gaps = 1/105 (0%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
+V LP L ++SG I+S EGD +++ + E+ETDKAT+ T G + K+ +
Sbjct: 4 EVKLPELGDGIDSGDILSVYVSEGDVVTKNQNILELETDKATVEIPTNVAGKVTKVHVKT 63
Query: 462 GTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPA-TPQKPASQDK 593
G VP+G L + + ++ AA K++S PA P+K A K
Sbjct: 64 G-DAVPIGGALISV--EASEGAA----KEESKPAPAPKKEAEAPK 101
>UniRef50_A1UIB1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=4; Actinomycetales|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Mycobacterium sp. (strain KMS)
Length = 629
Score = 52.0 bits (119), Expect = 2e-05
Identities = 31/93 (33%), Positives = 48/93 (51%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
+ V +PAL ++ G++ W K+EGD + + + L E+ TDK +P G L KI +
Sbjct: 21 VSVQMPALGESVTEGTVTRWLKQEGDTVEQDEPLLEVSTDKVDTEIPSPASGVLQKI-VA 79
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSS 557
V VG L +I G+ + + D DDSS
Sbjct: 80 QEDDTVEVGGELAVI-GEGGEDSG--DSSDDSS 109
Score = 41.1 bits (92), Expect = 0.030
Identities = 30/98 (30%), Positives = 45/98 (45%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +P L ++ G++ W KK GD + + L E+ TDK +P G L +I I
Sbjct: 170 VTMPELGESVTEGTVTRWLKKVGDSVEVDEPLLEVSTDKVDTEIPSPVAGTLLEI-IAEE 228
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKP 578
V VG L I GD D A ++ + + P +P
Sbjct: 229 DDTVEVGGELAKI-GDA-DQAEAEEPEPEPEPEPEPEP 264
>UniRef50_A0G901 Cluster: Biotin/lipoyl attachment; n=1;
Burkholderia phymatum STM815|Rep: Biotin/lipoyl
attachment - Burkholderia phymatum STM815
Length = 130
Score = 52.0 bits (119), Expect = 2e-05
Identities = 27/73 (36%), Positives = 39/73 (53%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +P TM G+++ W K GDK+ G L E+E+ K E G L +I+I AG
Sbjct: 7 VTIPKWGMTMTEGTVLEWHAKVGDKVERGQELLEVESTKVNNVVEATVSGILRRIVIDAG 66
Query: 465 TKGVPVGKLLCII 503
+ PVG L+ +I
Sbjct: 67 -EIAPVGALIGVI 78
>UniRef50_P65634 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=12; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Mycobacterium bovis
Length = 553
Score = 52.0 bits (119), Expect = 2e-05
Identities = 35/101 (34%), Positives = 51/101 (50%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +PAL ++ G++ W K+EGD + + L E+ TDK +P G L KI I
Sbjct: 5 VQMPALGESVTEGTVTRWLKQEGDTVELDEPLVEVSTDKVDTEIPSPAAGVLTKI-IAQE 63
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQ 587
V VG L +I GD KD + ++PA + PA+Q
Sbjct: 64 DDTVEVGGELAVI-GDA------KDAGEAAAPAPEKVPAAQ 97
Score = 42.7 bits (96), Expect = 0.010
Identities = 30/98 (30%), Positives = 41/98 (41%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +P L ++ G+++ W KK GD + + L E+ TDK +P G L I
Sbjct: 124 VLMPELGESVTEGTVIRWLKKIGDSVQVDEPLVEVSTDKVDTEIPSPVAGVLVSISADED 183
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKP 578
VPVG L I G D+ A K P P
Sbjct: 184 AT-VPVGGELARI-GVAADIGAAPAPKPAPKPVPEPAP 219
>UniRef50_P16263 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=95; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Bacillus subtilis
Length = 417
Score = 52.0 bits (119), Expect = 2e-05
Identities = 31/103 (30%), Positives = 56/103 (54%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
++ +P L+ ++ G+I W K+ GD + +G+ L E+ETDK + E G L ++L +
Sbjct: 3 EIKVPELAESISEGTIAQWLKQPGDYVEQGEYLLELETDKVNVELTAEESGVLQEVLKDS 62
Query: 462 GTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQD 590
G V VG+ I+G ++ A + S+PA +K S++
Sbjct: 63 GDT-VQVGE----IIGTISEGAG-----ESSAPAPTEKTESKE 95
>UniRef50_Q63TQ8 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex; n=42;
Proteobacteria|Rep: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex -
Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 425
Score = 51.6 bits (118), Expect = 2e-05
Identities = 29/108 (26%), Positives = 55/108 (50%), Gaps = 5/108 (4%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
++V +P LS ++ +++ W+KK G+ +++ ++L E+ETDK + P G LA++L
Sbjct: 4 VEVKVPQLSESVSEATMLQWKKKPGEAVAQDEILIELETDKVVLEVPAPAAGVLAQVLQN 63
Query: 459 AGTKGVPVGKLLCII-----VGDQNDVAAFKDFKDDSSPATPQKPASQ 587
G V +++ I G A D + ++P PA+Q
Sbjct: 64 DGDT-VVADQVIATIDTEAKAGAAAAAAGAADVQPAAAPVAAPAPAAQ 110
>UniRef50_Q3SEX1 Cluster: Dihydrolipoamide succinyltransferase; n=1;
Thiobacillus denitrificans ATCC 25259|Rep:
Dihydrolipoamide succinyltransferase - Thiobacillus
denitrificans (strain ATCC 25259)
Length = 379
Score = 51.6 bits (118), Expect = 2e-05
Identities = 27/101 (26%), Positives = 53/101 (52%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
+V +P LS ++ SG+++ W K GD ++ + L ++ETDK + P G L ++
Sbjct: 4 EVRVPTLSDSVASGTLLPWRKAVGDTVARDETLVDLETDKVILEIPAPASGTLVEVRAVG 63
Query: 462 GTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPAS 584
G + V +++ +I + A ++ ++PA P PA+
Sbjct: 64 GAE-VRADEVIALIETGEAAAAGARENATPAAPA-PAPPAA 102
>UniRef50_A0LP66 Cluster: 2-oxoglutarate dehydrogenase, E2 subunit,
dihydrolipoamide succinyltransferase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: 2-oxoglutarate
dehydrogenase, E2 subunit, dihydrolipoamide
succinyltransferase - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 444
Score = 51.6 bits (118), Expect = 2e-05
Identities = 25/75 (33%), Positives = 46/75 (61%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I+V +P + +++ +V W +++GD + +G++L IETDK T+ +G L KIL+P
Sbjct: 3 IEVKVPEVGESVQEALLVQWYRRDGDMVRKGEILFIIETDKVTLEVSADADG-LLKILVP 61
Query: 459 AGTKGVPVGKLLCII 503
G + V +G ++ I
Sbjct: 62 EG-QTVRIGTVVATI 75
>UniRef50_A0H074 Cluster: E3 binding; n=2; Chloroflexus|Rep: E3
binding - Chloroflexus aggregans DSM 9485
Length = 467
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/74 (35%), Positives = 43/74 (58%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
+V +P +M+ G I W K+EG+ + +G+ + E+ET+K T E P G LA++ P
Sbjct: 4 EVVMPKWGLSMQEGKINLWLKREGEAVQQGEPIAEVETEKITNVVEAPVSGVLARLCYPE 63
Query: 462 GTKGVPVGKLLCII 503
G+ V V K++ I
Sbjct: 64 GSI-VAVTKVIAYI 76
>UniRef50_A0G738 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=4; Burkholderiaceae|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Burkholderia phymatum STM815
Length = 382
Score = 51.2 bits (117), Expect = 3e-05
Identities = 22/76 (28%), Positives = 46/76 (60%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I+ LP++ M+ G+++ W+ K GD +++G ++ ++T KA + E+ EG + +++
Sbjct: 2 IEFTLPSMGADMDEGTLLEWKIKPGDAVTKGQIVAIVDTSKAAVDIESWYEGTVYELITE 61
Query: 459 AGTKGVPVGKLLCIIV 506
G K +PVG + I +
Sbjct: 62 PGEK-IPVGTPMAIFL 76
>UniRef50_Q4AFC2 Cluster: Biotin/lipoyl attachment; n=1; Chlorobium
phaeobacteroides BS1|Rep: Biotin/lipoyl attachment -
Chlorobium phaeobacteroides BS1
Length = 119
Score = 50.8 bits (116), Expect = 4e-05
Identities = 26/74 (35%), Positives = 40/74 (54%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
++ +P L ++ +I W K G+ + E D L EI TDK +P EG L+K+L
Sbjct: 5 EIIMPKLGESIIEATITRWVKNVGEAVEEDDSLVEIATDKVDSEIPSPVEGVLSKLLFKE 64
Query: 462 GTKGVPVGKLLCII 503
G VPVG ++ +I
Sbjct: 65 GDV-VPVGTVIALI 77
>UniRef50_Q1AT73 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Rubrobacter xylanophilus
DSM 9941|Rep: Catalytic domain of components of various
dehydrogenase complexes - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 441
Score = 50.8 bits (116), Expect = 4e-05
Identities = 21/73 (28%), Positives = 42/73 (57%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ +P L ++ G+I W K EGD++ + + + E++TDK + +P G + ++L+P G
Sbjct: 5 ITMPQLGESVTEGTIARWLKAEGDEVEKDEPIAEVDTDKVSAELPSPLAGRIERLLVPEG 64
Query: 465 TKGVPVGKLLCII 503
V VG + ++
Sbjct: 65 AT-VEVGTEIALV 76
>UniRef50_Q0A5F2 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Bacteria|Rep: Catalytic
domain of components of various dehydrogenase complexes
- Alkalilimnicola ehrlichei (strain MLHE-1)
Length = 441
Score = 50.8 bits (116), Expect = 4e-05
Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 1/102 (0%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+P+L M SG +V W + GD++ +G ++ +ET+K + E E G + + GT+
Sbjct: 6 MPSLGADMASGELVEWRVRPGDRVEKGQVIAVVETNKGAIEVEVFESGVVEALYEEPGTR 65
Query: 471 GVPVGKLLCIIVGDQNDVAAFKDF-KDDSSPATPQKPASQDK 593
+PVG + I GD + A + K + P KP + K
Sbjct: 66 -LPVGAPMARI-GDGRGLEAGEGSPKPEPKPEPKPKPEPKPK 105
>UniRef50_Q5HKM0 Cluster: Acetoin dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase; n=3;
Staphylococcus|Rep: Acetoin dehydrogenase, E2 component,
dihydrolipoamide acetyltransferase - Staphylococcus
epidermidis (strain ATCC 35984 / RP62A)
Length = 425
Score = 50.4 bits (115), Expect = 5e-05
Identities = 29/89 (32%), Positives = 47/89 (52%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+P L TM+ G++ W K EGD + +G+ + I ++K T E P G L +I + AG
Sbjct: 7 MPKLGMTMKEGTVEEWFKSEGDTVKQGESIVTISSEKLTNDVEAPASGTLLEIKVQAGED 66
Query: 471 GVPVGKLLCIIVGDQNDVAAFKDFKDDSS 557
K + I+G++ + A KD D +S
Sbjct: 67 AEV--KAVLGIIGEEGE-AIDKDEDDLAS 92
>UniRef50_O32959 Cluster: Dihydrolipoamide succinyltransferase; n=1;
Mycobacterium leprae|Rep: Dihydrolipoamide
succinyltransferase - Mycobacterium leprae
Length = 530
Score = 50.4 bits (115), Expect = 5e-05
Identities = 33/100 (33%), Positives = 47/100 (47%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +PAL ++ G++ W K+EGD + + L E+ TDK +P G L KI I
Sbjct: 5 VQMPALGESVTEGTVTRWLKQEGDTVELDEPLVEVSTDKVDTEIPSPAAGVLTKI-IAQE 63
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPAS 584
V VG L +I G ++ AA A P+ AS
Sbjct: 64 DDTVEVGGELAVI-GAPSEAAAAAPAPRPEPKAQPEPAAS 102
Score = 42.3 bits (95), Expect = 0.013
Identities = 23/67 (34%), Positives = 32/67 (47%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +P L ++ G++ W KK GD + + L E+ TDK +P G L I
Sbjct: 121 VLMPELGESVTEGTVTRWLKKIGDSVQADEPLVEVSTDKVDTEIPSPVAGVLVSITTNED 180
Query: 465 TKGVPVG 485
T VPVG
Sbjct: 181 TT-VPVG 186
>UniRef50_Q49XM4 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=35; Bacillales|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 424
Score = 50.4 bits (115), Expect = 5e-05
Identities = 23/74 (31%), Positives = 43/74 (58%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
+V +P L+ ++ G+I W K+ GD + +G+ + E+ETDK + + E G L ++L
Sbjct: 3 EVKVPELAESITEGTIAEWLKQVGDSVDKGEAIVELETDKVNVEVVSEEAGVLQELLANE 62
Query: 462 GTKGVPVGKLLCII 503
G V VG+ + ++
Sbjct: 63 GDT-VEVGQAIAVV 75
>UniRef50_Q5FS04 Cluster: Dihydrolipoamide succinyl transferase (E2)
of 2-oxoglutarate dehydrogenase; n=6; cellular
organisms|Rep: Dihydrolipoamide succinyl transferase
(E2) of 2-oxoglutarate dehydrogenase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 369
Score = 49.6 bits (113), Expect = 9e-05
Identities = 29/108 (26%), Positives = 53/108 (49%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
+++ +PAL ++ + ++ W KK GD + + + E+ETDK ++ P G L + +
Sbjct: 3 VEIRVPALGESLTTATVARWLKKSGDYVQHDETIVELETDKVSVEVTAPSAGRL-EDCVA 61
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQDKXLA 602
GT+ V +G LL + AA + +PA P P + +A
Sbjct: 62 VGTE-VEIGGLLGAVDETAEAPAAPEPAPVAEAPAEPAAPPPAPEPVA 108
>UniRef50_Q39RZ0 Cluster: Dihydrolipoamide succinyltransferase; n=3;
Geobacter|Rep: Dihydrolipoamide succinyltransferase -
Geobacter metallireducens (strain GS-15 / ATCC 53774 /
DSM 7210)
Length = 418
Score = 49.6 bits (113), Expect = 9e-05
Identities = 24/81 (29%), Positives = 45/81 (55%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
+++ +P++ ++ + W KK G+ + + + +CEIETDK TM + +G L I++P
Sbjct: 1 MEIKVPSVGESVYEALVGKWLKKNGEAVRKDEPVCEIETDKITMEIDAGADGVLT-IMVP 59
Query: 459 AGTKGVPVGKLLCIIVGDQND 521
G V +G ++ II D
Sbjct: 60 EGAT-VKIGSVIGIIEAGTGD 79
>UniRef50_A3CMZ5 Cluster: Dihydrolipoamide acetyl transferase, E2
component, putative; n=2; Streptococcus|Rep:
Dihydrolipoamide acetyl transferase, E2 component,
putative - Streptococcus sanguinis (strain SK36)
Length = 419
Score = 49.6 bits (113), Expect = 9e-05
Identities = 27/74 (36%), Positives = 40/74 (54%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
++ +P L TM G I +W KEGD ++ G + EI ++K T E P G + KI+ A
Sbjct: 4 EIVMPKLGLTMTEGLINNWLVKEGDTVAAGQPVLEISSEKLTSDVEAPSAGVILKIISQA 63
Query: 462 GTKGVPVGKLLCII 503
G VP K++ I
Sbjct: 64 GDT-VPCKKVIAWI 76
>UniRef50_A1UBW5 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=11; Mycobacterium|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Mycobacterium sp. (strain KMS)
Length = 399
Score = 49.6 bits (113), Expect = 9e-05
Identities = 24/71 (33%), Positives = 40/71 (56%), Gaps = 3/71 (4%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+PAL M+ G++ W K GD ++ G ++ +ET KA + E +EG + ++L+P G
Sbjct: 6 MPALGSDMDEGTLDQWLVKPGDTVTRGQVVAVVETTKAAVEVECWQEGTVDRLLVPEGQT 65
Query: 471 ---GVPVGKLL 494
G P+ LL
Sbjct: 66 VRVGTPLATLL 76
>UniRef50_Q5UYG4 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Halobacteriaceae|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex - Haloarcula
marismortui (Halobacterium marismortui)
Length = 545
Score = 49.6 bits (113), Expect = 9e-05
Identities = 26/92 (28%), Positives = 47/92 (51%)
Frame = +3
Query: 288 NLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGT 467
NLP L + G +++W GD ++E +L E+ETDKA + +P +G + ++ G
Sbjct: 5 NLPDLGEGVAEGEVLTWRVSPGDAVTEDQVLAEVETDKAAVDVPSPVDGVVQELHAEVG- 63
Query: 468 KGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPA 563
+ V G++L I + ++ D D+ A
Sbjct: 64 EMVQTGEVL-ITIAEEGDAETADAAASDTDEA 94
>UniRef50_A5UTW4 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=5; Chloroflexi (class)|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Roseiflexus sp. RS-1
Length = 434
Score = 49.2 bits (112), Expect = 1e-04
Identities = 28/83 (33%), Positives = 43/83 (51%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
+ + LP + +M +I W K+ GD++ + L E+ETDK + + G L +I P
Sbjct: 3 VDIVLPQIGESMTEATIGRWLKRVGDRVERYEALVEVETDKVSTEVTSITSGVLLEIATP 62
Query: 459 AGTKGVPVGKLLCIIVGDQNDVA 527
G VPVG LL I G+ + A
Sbjct: 63 EGAT-VPVGALLARI-GEPGEAA 83
>UniRef50_A0LAA3 Cluster: 2-oxoglutarate dehydrogenase, E2 subunit,
dihydrolipoamide succinyltransferase; n=11;
Proteobacteria|Rep: 2-oxoglutarate dehydrogenase, E2
subunit, dihydrolipoamide succinyltransferase -
Magnetococcus sp. (strain MC-1)
Length = 446
Score = 49.2 bits (112), Expect = 1e-04
Identities = 24/75 (32%), Positives = 43/75 (57%), Gaps = 1/75 (1%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
++ +P L ++ ++V W K+ GD ++ + L E+ETDK T+ +P G + +I A
Sbjct: 4 EIKVPTLGESVTEATVVQWLKQVGDAVAVDEPLVELETDKVTVEMPSPVAGVITEIY--A 61
Query: 462 GTKG-VPVGKLLCII 503
G V VG +LC++
Sbjct: 62 GVDADVEVGAVLCVV 76
>UniRef50_Q5BY55 Cluster: SJCHGC04170 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04170 protein - Schistosoma
japonicum (Blood fluke)
Length = 233
Score = 49.2 bits (112), Expect = 1e-04
Identities = 23/62 (37%), Positives = 37/62 (59%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
VN+P + ++ G IV W+K GD + E D++ EIETDK + P G + ++L+ G
Sbjct: 62 VNVPPFAESVTEGDIV-WKKAIGDIVKEDDVIAEIETDKTNVPVPAPCAGVITQLLVEDG 120
Query: 465 TK 470
+K
Sbjct: 121 SK 122
>UniRef50_Q234F3 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
2-oxoglutarate dehydrogenase, E2 component,
dihydrolipoamide succinyltransferase family protein -
Tetrahymena thermophila SB210
Length = 564
Score = 49.2 bits (112), Expect = 1e-04
Identities = 37/149 (24%), Positives = 69/149 (46%), Gaps = 3/149 (2%)
Frame = +3
Query: 75 LRTIVLRNQILSDGLKKAIRSNITRCIS-TELAKRKVTNKLLE-HAQNQTVLSTPQWTVQ 248
L I + +L K +RS I + + +L K L+ +A+N + Q
Sbjct: 74 LNKIRRKKNLLKIKASKKMRSAIKKLLPLVQLTKTMPKYSLVTVNAKNSMKIKQFQSQYL 133
Query: 249 MRYYSSLPSHIK-VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETP 425
+ + S IK +N+P++ ++ G + KK GD + +++C +ETDK + +P
Sbjct: 134 LTHTSKANFAIKTINVPSMGDSITEGQVHQMLKKVGDYVELDEVVCSVETDKTQVPIRSP 193
Query: 426 EEGYLAKILIPAGTKGVPVGKLLCIIVGD 512
E G + ++ G + V VGK ++ D
Sbjct: 194 EAGVITELFAQEG-ENVNVGKPFFVLDTD 221
>UniRef50_Q6L1M0 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Thermoplasmatales|Rep: Dihydrolipoamide
acetyltransferase component of pyruvate dehydrogenase
complex - Picrophilus torridus
Length = 386
Score = 49.2 bits (112), Expect = 1e-04
Identities = 25/73 (34%), Positives = 38/73 (52%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ +P + + G IV W KEGD + + + EI TDK T+ +P G + K++ P G
Sbjct: 4 LKVPPIGEGVSEGEIVKWNVKEGDTIEKDQEIVEIMTDKITIKIPSPVSGKVLKLIEPEG 63
Query: 465 TKGVPVGKLLCII 503
K V VG + I
Sbjct: 64 -KTVKVGDSIATI 75
>UniRef50_Q5L233 Cluster: Pyruvate dehydrogenase E2; n=2;
Geobacillus|Rep: Pyruvate dehydrogenase E2 - Geobacillus
kaustophilus
Length = 436
Score = 48.8 bits (111), Expect = 1e-04
Identities = 25/75 (33%), Positives = 39/75 (52%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
++V LP LS + + I W EGD + +G L E++T+KA PE G + +I
Sbjct: 3 VEVTLPKLSDSHDESFITFWHVSEGDAVEKGATLVEVQTEKAVSEIHAPESGTVKEIKKK 62
Query: 459 AGTKGVPVGKLLCII 503
G VG++L +I
Sbjct: 63 RGDT-AKVGEVLAVI 76
>UniRef50_Q7X2B2 Cluster: PdhC; n=1; Lactobacillus reuteri|Rep: PdhC
- Lactobacillus reuteri
Length = 285
Score = 48.8 bits (111), Expect = 1e-04
Identities = 34/103 (33%), Positives = 52/103 (50%), Gaps = 2/103 (1%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
K LP + + G I S+ KEGD++ +GD L EI+TDK+T +P G + KI
Sbjct: 4 KFRLPEMGEGLTEGDIASFLVKEGDQVKDGDPLVEIQTDKSTTQLVSPVAGTIKKIEAKE 63
Query: 462 GTKGVPVGKLLCIIVGDQNDVAAFKDFK--DDSSPATPQKPAS 584
V G L +I ++ V+ D + DDS+ T + +S
Sbjct: 64 DDH-VEKGNDLVLIDDGKDGVSTNVDAEDADDSADDTAAEESS 105
>UniRef50_A2TU26 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-ketoacid dehydrogenase complex;
n=4; Bacteroidetes|Rep: Lipoamide acyltransferase
component of branched-chain alpha-ketoacid dehydrogenase
complex - Dokdonia donghaensis MED134
Length = 439
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/111 (28%), Positives = 48/111 (43%), Gaps = 2/111 (1%)
Frame = +3
Query: 267 LPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAK 446
L S + +P + ++ G+I++W EG+ EGD+L EI TDK G + K
Sbjct: 8 LMSATSLLMPKMGESITEGTIINWLVAEGESFEEGDILVEIATDKVDNEVPATSAGVMQK 67
Query: 447 ILIPAGTKGVPVGKLLCIIVGDQNDV--AAFKDFKDDSSPATPQKPASQDK 593
L A V VG+ + + D A K ++ P Q P Q K
Sbjct: 68 HLYDANAV-VAVGEPIATYLAQGGDAEKAINPSEKKEAQPTKAQTPKKQAK 117
>UniRef50_A0H458 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=2;
Chloroflexus|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase -
Chloroflexus aggregans DSM 9485
Length = 469
Score = 48.8 bits (111), Expect = 1e-04
Identities = 22/71 (30%), Positives = 40/71 (56%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
++ +P+L ++ ++ W K+EG+ ++ G+ + E+ETDK + + G L I P
Sbjct: 4 EIRVPSLGESIVEATVARWLKREGEAVAIGEPVVELETDKVNLEVAADQSGVLVSIASPE 63
Query: 462 GTKGVPVGKLL 494
GT V +G LL
Sbjct: 64 GTT-VAIGDLL 73
>UniRef50_Q6MPR6 Cluster: Pyruvate dehydrogenase E2; n=1;
Bdellovibrio bacteriovorus|Rep: Pyruvate dehydrogenase
E2 - Bdellovibrio bacteriovorus
Length = 543
Score = 48.4 bits (110), Expect = 2e-04
Identities = 30/101 (29%), Positives = 46/101 (45%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V LP L + G +V W K GD + + E+ TDKAT+ TP G + ++ +G
Sbjct: 122 VKLPELGEGVTEGELVKWLVKPGDSVKADQAIAEVLTDKATVEVPTPVAGVVKELKFKSG 181
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQ 587
V VG + I+ G A ++PA PA++
Sbjct: 182 DV-VKVGSTMIILEGAGGAAAPKAAPAAAAAPAPAAAPATK 221
Score = 41.1 bits (92), Expect = 0.030
Identities = 23/75 (30%), Positives = 35/75 (46%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V LP L + G +V W K GD + + E+ TDKAT+ +P G + + +G
Sbjct: 14 VKLPELGEGVTEGELVKWLVKPGDAVKADQAIAEVLTDKATVEVPSPVAGVVKDLKFKSG 73
Query: 465 TKGVPVGKLLCIIVG 509
V VG + + G
Sbjct: 74 DV-VKVGATMITLDG 87
>UniRef50_A6PBA2 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Shewanella sediminis
HAW-EB3|Rep: Catalytic domain of components of various
dehydrogenase complexes - Shewanella sediminis HAW-EB3
Length = 377
Score = 48.4 bits (110), Expect = 2e-04
Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 1/105 (0%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKIL-IPAGT 467
+P+L M G +V W K GD + GD++ IET K + E G +++IL P T
Sbjct: 1 MPSLGADMTEGMLVEWLVKRGDPVKRGDIIAVIETQKGAIDMEVYHTGVISEILHQPVVT 60
Query: 468 KGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQDKXLA 602
+PVG ++ + +D PQ + D+ A
Sbjct: 61 --LPVGTVMARVETQASDREVAATIAPQIDTVAPQIDTAADRVAA 103
>UniRef50_A6C4P4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex dihydrolipoamide acyltransferase (E2) component
and related enzyme; n=1; Planctomyces maris DSM
8797|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex
dihydrolipoamide acyltransferase (E2) component and
related enzyme - Planctomyces maris DSM 8797
Length = 449
Score = 48.4 bits (110), Expect = 2e-04
Identities = 26/104 (25%), Positives = 55/104 (52%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
LP +S +E+ + GD + +G +L +IETDKA + E+P G + ++ + G
Sbjct: 7 LPEVSEGVETADVGQISVAVGDTVEQGQVLMDIETDKAVVQLESPYSGTIEELKVSEG-D 65
Query: 471 GVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQDKXLA 602
V +G +L +++ + N A+ ++ S+ ++P +++ A
Sbjct: 66 SVSIGAVL-LLINESNGDASAPAKEEKSAETKAEEPVAEEPETA 108
>UniRef50_A1T0M1 Cluster: Pyruvate dehydrogenase complex, E2
component dihydrolipoamide acetyltransferase; n=1;
Psychromonas ingrahamii 37|Rep: Pyruvate dehydrogenase
complex, E2 component dihydrolipoamide acetyltransferase
- Psychromonas ingrahamii (strain 37)
Length = 451
Score = 48.4 bits (110), Expect = 2e-04
Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 3/72 (4%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ +P+ M+ G++V W KEGD + GD++ IET K + + E+ + +LI G
Sbjct: 8 LKMPSFGSDMKKGTLVQWLVKEGDHIKRGDVVAVIETHKGAIDLDLFEDALIISLLIKEG 67
Query: 465 TK---GVPVGKL 491
+ G P+ +L
Sbjct: 68 QQIAVGEPIARL 79
>UniRef50_A1SJ23 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=18; Actinomycetales|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Nocardioides sp. (strain BAA-499 / JS614)
Length = 597
Score = 48.4 bits (110), Expect = 2e-04
Identities = 31/101 (30%), Positives = 50/101 (49%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V LPAL ++ G++ W K GD+++ + L E+ TDK +P G L +I + A
Sbjct: 142 VTLPALGESVTEGTVTRWLKSVGDEVAVDEPLLEVSTDKVDTEIPSPVAGTLLEIKV-AE 200
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQ 587
+ V VG L +I Q AA + K + +P +P +
Sbjct: 201 DETVEVGAELAVIGSGQ---AAPAESKPEPTPEPEPEPTPE 238
Score = 46.4 bits (105), Expect = 8e-04
Identities = 27/80 (33%), Positives = 42/80 (52%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
+VNLPAL ++ G++ W K+ GD ++ + L E+ TDK +P G L +I
Sbjct: 4 EVNLPALGESVTEGTVTRWLKQVGDSVAVDEPLLEVSTDKVDTEIPSPIAGTLLEIRANE 63
Query: 462 GTKGVPVGKLLCIIVGDQND 521
V VG +L +I GD +
Sbjct: 64 DDT-VEVGAVLAVI-GDAGE 81
>UniRef50_Q9FC63 Cluster: Putative acyltransferase; n=1;
Streptomyces coelicolor|Rep: Putative acyltransferase -
Streptomyces coelicolor
Length = 417
Score = 48.0 bits (109), Expect = 3e-04
Identities = 27/75 (36%), Positives = 40/75 (53%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
+ V LPAL ++ G++ W K+ GD++ + L E+ TDK +P G L +IL
Sbjct: 3 VSVTLPALGESVTEGTVTRWLKQVGDRVEADEPLLEVSTDKVDTEIPSPAAGVLLEIL-A 61
Query: 459 AGTKGVPVGKLLCII 503
A + V VG L II
Sbjct: 62 AEDETVEVGAGLGII 76
>UniRef50_A5V4B2 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Sphingomonas wittichii
RW1|Rep: Catalytic domain of components of various
dehydrogenase complexes - Sphingomonas wittichii RW1
Length = 420
Score = 48.0 bits (109), Expect = 3e-04
Identities = 26/79 (32%), Positives = 38/79 (48%)
Frame = +3
Query: 333 SWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTKGVPVGKLLCIIVGD 512
SW + GD++ E D L E+ETDK T P G +A+IL+ + + P L + VGD
Sbjct: 21 SWLRNVGDRVEENDPLVELETDKVTQEVPAPAAGVIAEILLASDAEAEPGALLGRLRVGD 80
Query: 513 QNDVAAFKDFKDDSSPATP 569
+ A + A P
Sbjct: 81 EAAAGATPPAASGDAGAEP 99
>UniRef50_Q3A0D1 Cluster: 2-oxoglutarate dehydrogenase, E2
component/dihydrolipoamide succinyltransferase; n=2;
Desulfuromonadales|Rep: 2-oxoglutarate dehydrogenase, E2
component/dihydrolipoamide succinyltransferase -
Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 396
Score = 47.6 bits (108), Expect = 3e-04
Identities = 21/99 (21%), Positives = 47/99 (47%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ +P + ++ + W ++G ++ + DLLCE+ETDK T+ +G + L
Sbjct: 3 IRIPEIGESIIEAKLAKWHCQDGAQVQKDDLLCELETDKITLELFAETDGVVT--LRTEE 60
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPA 581
+ VP+G ++ ++ + + + P + +PA
Sbjct: 61 GETVPIGTVIAVLTEEAGQAQTTEPLEPSEPPPSDTQPA 99
>UniRef50_Q59658 Cluster: Dihydrolipoamide acetyltransferase; n=3;
Pelobacter|Rep: Dihydrolipoamide acetyltransferase -
Pelobacter carbinolicus
Length = 450
Score = 47.6 bits (108), Expect = 3e-04
Identities = 28/78 (35%), Positives = 39/78 (50%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I + +P TME G+I SW EGD + G + E+ETDK E+ EG L + I
Sbjct: 7 IALTMPKWGLTMEEGTISSWLMDEGDTIEVGSEILEVETDKIAQPVESAVEGILRR-KIG 65
Query: 459 AGTKGVPVGKLLCIIVGD 512
+ PV L+ II +
Sbjct: 66 EEDEEYPVKALIGIIAAE 83
Score = 42.7 bits (96), Expect = 0.010
Identities = 26/74 (35%), Positives = 38/74 (51%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
++ +P TME G+I SW EGD++ G + E+ETDK E+ G L + I
Sbjct: 123 ELTMPKWGLTMEEGTISSWLIDEGDEVEVGTEIMEVETDKIAQPVESTVAGVLRR-KIGE 181
Query: 462 GTKGVPVGKLLCII 503
+ PV L+ II
Sbjct: 182 EDEEYPVKALIGII 195
>UniRef50_Q1QQR6 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=2;
Proteobacteria|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase -
Nitrobacter hamburgensis (strain X14 / DSM 10229)
Length = 413
Score = 47.6 bits (108), Expect = 3e-04
Identities = 25/71 (35%), Positives = 40/71 (56%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
++ +P L ++ +I W KK GD ++ + L E+ETDK T+ P G L++I+
Sbjct: 3 EIRVPTLGESVTEATIGKWFKKAGDAVAVDEPLVELETDKVTIEVPAPSAGTLSEIVAKD 62
Query: 462 GTKGVPVGKLL 494
G + V VG LL
Sbjct: 63 G-ETVAVGALL 72
>UniRef50_A0LQU7 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Acidothermus
cellulolyticus 11B|Rep: Catalytic domain of components
of various dehydrogenase complexes - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 546
Score = 47.6 bits (108), Expect = 3e-04
Identities = 23/65 (35%), Positives = 36/65 (55%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
LP + + I W + GD++ + ++ EIET KA + +P G +A+IL+ GT
Sbjct: 9 LPDVGEGLTEAEITRWHVRPGDRVGQNQVIAEIETAKALVELPSPFAGIVAEILVAEGTT 68
Query: 471 GVPVG 485
VPVG
Sbjct: 69 -VPVG 72
>UniRef50_Q9FLQ4 Cluster: 2-oxoglutarate dehydrogenase E2 subunit;
n=15; Magnoliophyta|Rep: 2-oxoglutarate dehydrogenase E2
subunit - Arabidopsis thaliana (Mouse-ear cress)
Length = 464
Score = 47.6 bits (108), Expect = 3e-04
Identities = 31/133 (23%), Positives = 59/133 (44%), Gaps = 5/133 (3%)
Frame = +3
Query: 210 NQTVLSTPQWTVQMRYYSSLPSH----IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDL 377
++T+++ Q T R+ S ++ +P + ++ G++ ++ KK GD++ +
Sbjct: 67 SRTIINGYQGTALQRWVRPFSSDSGDVVEAVVPHMGESITDGTLAAFLKKPGDRVEADEA 126
Query: 378 LCEIETDKATMGFETPEEGYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSS 557
+ +IETDK T+ +P G + + L+ G P K+ I K
Sbjct: 127 IAQIETDKVTIDIASPASGVIQEFLVKEGDTVEPGNKVARISTSADAVSHVAPSEKAPEK 186
Query: 558 PA-TPQKPASQDK 593
PA P PA + K
Sbjct: 187 PAPKPSPPAEKPK 199
>UniRef50_Q0E0X4 Cluster: Os02g0514700 protein; n=2; Oryza
sativa|Rep: Os02g0514700 protein - Oryza sativa subsp.
japonica (Rice)
Length = 497
Score = 47.6 bits (108), Expect = 3e-04
Identities = 30/114 (26%), Positives = 51/114 (44%)
Frame = +3
Query: 243 VQMRYYSSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFET 422
V M + L + +P + ++ G++ ++ KK GD++ + + +IETDK TM +
Sbjct: 119 VFMDAHCQLGDLVDAVVPFMGESITDGTLATFLKKPGDRVEADEPIAQIETDKVTMDVAS 178
Query: 423 PEEGYLAKILIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPAS 584
PE G + K + G P G + II +D+S KP S
Sbjct: 179 PEAGIIEKFVASEGGIVTP-GVKVAIISKSAAQSKTHTQSSEDTSQKHSTKPPS 231
>UniRef50_Q7ULX6 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex; n=10;
Bacteria|Rep: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex -
Rhodopirellula baltica
Length = 435
Score = 47.2 bits (107), Expect = 5e-04
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKI 449
I V +P + ++ I +W K+EGD + G+ L EIET+KA++ P GYL I
Sbjct: 5 IPVEVPTVGESISEVQIGNWLKQEGDWVKSGEDLVEIETEKASVQIPAPASGYLQSI 61
>UniRef50_Q1GTH9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=5; Alphaproteobacteria|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Sphingopyxis alaskensis (Sphingomonas
alaskensis)
Length = 441
Score = 47.2 bits (107), Expect = 5e-04
Identities = 23/76 (30%), Positives = 40/76 (52%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
LP + + IV+W K G+++ E L ++ TDKAT+ E+P G + ++ G
Sbjct: 8 LPDIGEGIAEAEIVAWHVKVGERVEEDAQLADMMTDKATVEMESPVSGVVVELAGEVGDL 67
Query: 471 GVPVGKLLCIIVGDQN 518
+P+G L +I D +
Sbjct: 68 -IPIGSTLAVIETDDD 82
>UniRef50_Q0RVL0 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=1; Rhodococcus sp. RHA1|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 422
Score = 47.2 bits (107), Expect = 5e-04
Identities = 20/54 (37%), Positives = 31/54 (57%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYL 440
I + LP L M+S + W +K+GD++ G+++ IETDK + E P G L
Sbjct: 3 IDITLPQLGVEMKSALLAEWVRKDGDEVDGGEVIAIIETDKVSYEIEAPTAGVL 56
>UniRef50_A0XBY6 Cluster: Biotin/lipoyl attachment domain-containing
protein; n=1; Dinoroseobacter shibae DFL 12|Rep:
Biotin/lipoyl attachment domain-containing protein -
Dinoroseobacter shibae DFL 12
Length = 398
Score = 47.2 bits (107), Expect = 5e-04
Identities = 31/98 (31%), Positives = 43/98 (43%), Gaps = 1/98 (1%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+P L TME +I W + G GD L E+ETDK + + +G L + L+ G
Sbjct: 1 MPRLGETMEEATIADWLVQPGQSFKRGDPLLEVETDKTMVEYPALGDGILVETLVGPGDV 60
Query: 471 GVPVGKLLCII-VGDQNDVAAFKDFKDDSSPATPQKPA 581
V VG + +I D D D S A P + A
Sbjct: 61 -VEVGTPIAVIETRDAWDSVEEPDAAASSPGAAPSEVA 97
>UniRef50_A6WD54 Cluster: 2-oxoglutarate dehydrogenase E2 component;
n=5; Actinomycetales|Rep: 2-oxoglutarate dehydrogenase
E2 component - Kineococcus radiotolerans SRS30216
Length = 618
Score = 46.8 bits (106), Expect = 6e-04
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +PAL ++ G++ W K GD + + L E+ TDK +P G L +IL+P
Sbjct: 5 VQMPALGESVTEGTVTRWLKAVGDTVEVDEPLLEVSTDKVDTEIPSPVAGTLLEILVPE- 63
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDF-KDDSSPATPQ 572
+ VG L I GD ++ ++ +PA PQ
Sbjct: 64 DETADVGADLARI-GDPSEQGGGSPAPQEQPAPAAPQ 99
Score = 42.7 bits (96), Expect = 0.010
Identities = 28/103 (27%), Positives = 45/103 (43%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +PAL ++ G++ W K GD + + L E+ TDK +P G L +IL+
Sbjct: 140 VKMPALGESVTEGTVTRWLKAVGDSVEVDEPLLEVSTDKVDTEIPSPVAGTLLEILV-GE 198
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQDK 593
+ VG L I + +PA PQ+ + D+
Sbjct: 199 DETADVGADLARIGDASAAPSPAPAAPAQEAPAAPQEESLADE 241
>UniRef50_A1ZHD0 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=2; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Microscilla marina ATCC 23134
Length = 454
Score = 46.8 bits (106), Expect = 6e-04
Identities = 26/96 (27%), Positives = 49/96 (51%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
+++ +P + ++ G+I+ W K GD++ E + + E+ TDK G L ++L
Sbjct: 4 VEMVMPKMGESVMEGTILQWLKAVGDEIEEDEPVLEVATDKVDTEVPATHAGVLKEVLAQ 63
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPAT 566
G V VG+ + II D + A + +++PAT
Sbjct: 64 EGDV-VQVGQTIAIISTDGDAPADAPASQPEAAPAT 98
>UniRef50_Q5UWH1 Cluster: Dihydrolipoamide S-acetyltransferase
component of pyruvate dehydrogenase complex E2; n=3;
Halobacteriaceae|Rep: Dihydrolipoamide
S-acetyltransferase component of pyruvate dehydrogenase
complex E2 - Haloarcula marismortui (Halobacterium
marismortui)
Length = 540
Score = 46.8 bits (106), Expect = 6e-04
Identities = 23/77 (29%), Positives = 41/77 (53%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
LP + + G ++ W + GD +SE + E+ETDKA + +P +G + ++ G +
Sbjct: 38 LPDVGEGVAEGELLRWRVEPGDAVSEDQPVAEVETDKAVVDVPSPVDGVVEELRAAEG-E 96
Query: 471 GVPVGKLLCIIVGDQND 521
VPVG ++ + D D
Sbjct: 97 MVPVGDVIIVFRVDGED 113
>UniRef50_Q92BY1 Cluster: Lin1411 protein; n=15; Bacillales|Rep:
Lin1411 protein - Listeria innocua
Length = 416
Score = 46.4 bits (105), Expect = 8e-04
Identities = 29/108 (26%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
K+ +P L ++ G+I SW K GD + + D + E+ TDK T + G + +IL
Sbjct: 5 KITMPKLGESVTEGTISSWLVKPGDTVEKYDAIAEVLTDKVTAEIPSSFSGTIKEILAEE 64
Query: 462 GTKGVPVGKLLCII-VGDQNDVAAFKDFKDDSSPATPQKPASQDKXLA 602
+ + VG+++C I D ++ + + A P+K ++ LA
Sbjct: 65 -DETLEVGEVICTIETADAGSSEPAEEVEQTETKA-PEKQETKQVKLA 110
>UniRef50_Q7NB00 Cluster: AceF; n=1; Mycoplasma gallisepticum|Rep:
AceF - Mycoplasma gallisepticum
Length = 440
Score = 46.4 bits (105), Expect = 8e-04
Identities = 28/86 (32%), Positives = 43/86 (50%)
Frame = +3
Query: 312 MESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTKGVPVGKL 491
+ G + K GD + EGD + +ETDK T PE G + IL G + V VG++
Sbjct: 13 LHEGVVAQIYVKVGDTIKEGDPMFSVETDKVTTDLPAPEGGKVTAILASVG-QTVHVGEV 71
Query: 492 LCIIVGDQNDVAAFKDFKDDSSPATP 569
+ ++ GD + A ++PATP
Sbjct: 72 MLVLNGDGSSAPA-------AAPATP 90
>UniRef50_Q6A613 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=1;
Propionibacterium acnes|Rep: Dihydrolipoamide
acetyltransferase component of pyruvate dehydrogenase
complex - Propionibacterium acnes
Length = 469
Score = 46.4 bits (105), Expect = 8e-04
Identities = 26/81 (32%), Positives = 39/81 (48%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+P + G +VSW+ GD + D+LCE+ET K+ + +P G +AK+ G +
Sbjct: 6 MPDPGEGLTEGEVVSWQVSPGDTVKINDVLCEVETAKSIVELPSPFAGTVAKLCAEPG-E 64
Query: 471 GVPVGKLLCIIVGDQNDVAAF 533
V VG L I D F
Sbjct: 65 TVAVGTPLVTIDDGSEDEPEF 85
>UniRef50_Q2J8A0 Cluster: Dehydrogenase subunit; n=9; Actinobacteria
(class)|Rep: Dehydrogenase subunit - Frankia sp. (strain
CcI3)
Length = 487
Score = 46.4 bits (105), Expect = 8e-04
Identities = 26/98 (26%), Positives = 47/98 (47%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
+ V +P L ++ G++ W K+EG+++ + L E+ TDK P G ++ I +
Sbjct: 3 VSVTMPRLGESVSEGTVTRWLKQEGERVEADEPLLEVSTDKVDTEIPAPASGVVSSIKV- 61
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQ 572
A + V VG L +I D + + +PA P+
Sbjct: 62 AEDETVEVGVELAVI-DDGSAGGGTAPAQATQAPAAPE 98
>UniRef50_A6TMP1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Alkaliphilus
metalliredigens QYMF|Rep: Catalytic domain of components
of various dehydrogenase complexes - Alkaliphilus
metalliredigens QYMF
Length = 438
Score = 46.4 bits (105), Expect = 8e-04
Identities = 18/52 (34%), Positives = 27/52 (51%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEG 434
++ P + + G + W K GD + EG+ LCE+ETDK T +P G
Sbjct: 2 VEFKFPDIGEGISEGILTKWMVKAGDNIKEGESLCEVETDKVTTELPSPATG 53
>UniRef50_A5V555 Cluster: Biotin/lipoyl attachment domain-containing
protein; n=1; Sphingomonas wittichii RW1|Rep:
Biotin/lipoyl attachment domain-containing protein -
Sphingomonas wittichii RW1
Length = 79
Score = 46.4 bits (105), Expect = 8e-04
Identities = 25/64 (39%), Positives = 33/64 (51%)
Frame = +3
Query: 273 SHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKIL 452
++IKV LP M+ IV W K GD + G+ L EIE K T+ +P G L +IL
Sbjct: 2 ANIKVLLPQFGMGMQEAEIVRWIKAVGDPVEAGEPLLEIEAAKTTVEVPSPGAGTLTEIL 61
Query: 453 IPAG 464
G
Sbjct: 62 AQEG 65
>UniRef50_A5EW59 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=1;
Dichelobacter nodosus VCS1703A|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase - Dichelobacter nodosus (strain
VCS1703A)
Length = 341
Score = 46.4 bits (105), Expect = 8e-04
Identities = 19/57 (33%), Positives = 33/57 (57%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKIL 452
+V +P L ++ +V+W K GD + +G+ L ++ETDK + P G +A+IL
Sbjct: 4 EVKIPTLPESVSDAILVNWHKSVGDFVEQGENLIDLETDKVMLEMPAPVSGIIAEIL 60
>UniRef50_Q5KP05 Cluster: Tricarboxylic acid cycle-related protein,
putative; n=2; Filobasidiella neoformans|Rep:
Tricarboxylic acid cycle-related protein, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 633
Score = 46.4 bits (105), Expect = 8e-04
Identities = 27/88 (30%), Positives = 44/88 (50%)
Frame = +3
Query: 327 IVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTKGVPVGKLLCIIV 506
I+ W +G + E D LCE+++DK+ + + +G + I G V VG +LC+I
Sbjct: 73 ILKWHVTDGQAVEEFDALCEVQSDKSVVELTSHAKGIVRDIKTDPGHM-VKVGTVLCVIE 131
Query: 507 GDQNDVAAFKDFKDDSSPATPQKPASQD 590
D+ +D +D A PQ +QD
Sbjct: 132 TDEPS----EDAAEDDLQAPPQLDNAQD 155
>UniRef50_Q5WE92 Cluster: Acetoin dehydrogenase E2 component; n=1;
Bacillus clausii KSM-K16|Rep: Acetoin dehydrogenase E2
component - Bacillus clausii (strain KSM-K16)
Length = 410
Score = 46.0 bits (104), Expect = 0.001
Identities = 19/50 (38%), Positives = 32/50 (64%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYL 440
+P L TM G+IV+W K+ G+ +++G+ + EI ++K T E E+G L
Sbjct: 6 MPKLGMTMSEGTIVNWCKEVGEPVTKGEAIVEISSEKLTQELEAQEDGIL 55
>UniRef50_A3U7C0 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-ketoacid dehydrogenase complex;
n=1; Croceibacter atlanticus HTCC2559|Rep: Lipoamide
acyltransferase component of branched-chain
alpha-ketoacid dehydrogenase complex - Croceibacter
atlanticus HTCC2559
Length = 480
Score = 46.0 bits (104), Expect = 0.001
Identities = 29/104 (27%), Positives = 48/104 (46%)
Frame = +3
Query: 273 SHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKIL 452
S +P + ++ G+I++W +EGD EGD+L EI TDK P G +
Sbjct: 2 SETAFKVPKMGESITEGTIINWVVQEGDAFEEGDILVEIATDKVDNEVPAPFSGVMISHK 61
Query: 453 IPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPAS 584
A V VG + I+ ++ + + K S+ + +K AS
Sbjct: 62 AQANDV-VAVGSEIAIL--EEGSSGSKSEEKSKSNLKSKEKEAS 102
>UniRef50_P21883 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=80; Bacilli|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex - Bacillus subtilis
Length = 442
Score = 46.0 bits (104), Expect = 0.001
Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 3/107 (2%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
LP + + G IV W K D++ E D+L E++ DKA + +P +G + ++ + GT
Sbjct: 7 LPDIGEGIHEGEIVKWFVKPNDEVDEDDVLAEVQNDKAVVEIPSPVKGKVLELKVEEGTV 66
Query: 471 GVPVGKLLCIIVGDQNDVAAFK--DFKDDS-SPATPQKPASQDKXLA 602
VG+ + + FK D DD+ + A Q A + +A
Sbjct: 67 AT-VGQTIITFDAPGYEDLQFKGSDESDDAKTEAQVQSTAEAGQDVA 112
>UniRef50_Q9RYB8 Cluster: 2-oxo acid dehydrogenase, E2 component;
n=2; Deinococcus|Rep: 2-oxo acid dehydrogenase, E2
component - Deinococcus radiodurans
Length = 525
Score = 45.6 bits (103), Expect = 0.001
Identities = 22/58 (37%), Positives = 33/58 (56%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
LP L+ ++ G I+ W +EGD ++ LCE+ TDK T+ +P EG L K + G
Sbjct: 6 LPELAESVVEGEILKWLVEEGDAIALEQPLCEVMTDKVTVELPSPFEGTLHKRMANEG 63
>UniRef50_Q9KG97 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillus
halodurans|Rep: Pyruvate dehydrogenase E2 - Bacillus
halodurans
Length = 414
Score = 45.6 bits (103), Expect = 0.001
Identities = 26/86 (30%), Positives = 44/86 (51%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
++ LP + M G I+SW +EGD + + + + E++TDK P G + ++
Sbjct: 2 VEFRLPDVGEGMHEGEIISWFVQEGDHVKQDEPVVEVQTDKMNAELTAPVSGKIKRVYYK 61
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFK 536
G + VG LL I D+N ++ FK
Sbjct: 62 VG-EVAEVGSLLFTI--DEN-LSTFK 83
>UniRef50_Q4L6L6 Cluster: Branched-chain alpha-keto acid
dehydrogenase E2; n=3; Staphylococcus|Rep:
Branched-chain alpha-keto acid dehydrogenase E2 -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 442
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/79 (29%), Positives = 40/79 (50%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ +P L ++ G+I W GD + E + LCE+ TDK T + G + +IL+ G
Sbjct: 3 IKMPKLGESVHEGTIEQWLISVGDYVDEYEPLCEVITDKVTAEVPSTVSGTITEILVSEG 62
Query: 465 TKGVPVGKLLCIIVGDQND 521
+ V + ++C I + D
Sbjct: 63 -ETVQIDHVICKIETSETD 80
>UniRef50_Q1YS54 Cluster: Dihydrolipoamide acetyltransferase; n=1;
gamma proteobacterium HTCC2207|Rep: Dihydrolipoamide
acetyltransferase - gamma proteobacterium HTCC2207
Length = 496
Score = 45.2 bits (102), Expect = 0.002
Identities = 30/99 (30%), Positives = 44/99 (44%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+N+P M G I +W GD+++ GD L +IET K + G L IL G
Sbjct: 8 INMPKWGMEMSEGDINAWYFAVGDEVNAGDDLVDIETSKIINTVTATDSGILRAILGATG 67
Query: 465 TKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPA 581
VG LL +I + A + F + +S A + A
Sbjct: 68 ETHA-VGALLGVIASAETSDADIQAFINSNSSAAAEPKA 105
>UniRef50_A7AT28 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex,
mitochondrial, putative; n=1; Babesia bovis|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex, mitochondrial,
putative - Babesia bovis
Length = 417
Score = 45.2 bits (102), Expect = 0.002
Identities = 22/87 (25%), Positives = 46/87 (52%)
Frame = +3
Query: 327 IVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTKGVPVGKLLCIIV 506
+V W K GD++ E + +C +++DKA + + G + K+ + G K + +G L + +
Sbjct: 48 LVRWNKNVGDEVEEMETVCTVQSDKAAVDITSRYTGLVKKLYVEQG-KLIKIGSPL-MDI 105
Query: 507 GDQNDVAAFKDFKDDSSPATPQKPASQ 587
++D A + + + + P KP +Q
Sbjct: 106 DAEDDTPAVSEPTETTKSSIPSKPVAQ 132
>UniRef50_P27747 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of acetoin cleaving system;
n=16; Proteobacteria|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of acetoin cleaving system -
Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 /
Stanier 337)(Cupriavidus necator (strain ATCC 17699 /
H16 / DSM 428 / Stanier337))
Length = 374
Score = 45.2 bits (102), Expect = 0.002
Identities = 29/111 (26%), Positives = 55/111 (49%)
Frame = +3
Query: 270 PSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKI 449
P+ I + +P +M+ G++ +W EG +++ G + ++ETDK E P+ G L +
Sbjct: 7 PTIIPIVMPKWGLSMKEGTVNAWLVDEGTEITVGLPILDVETDKIANAVEAPDAGTLRRK 66
Query: 450 LIPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQDKXLA 602
+ AG +PV LL ++ + A D+ ++ TP A ++ A
Sbjct: 67 VAQAGDV-LPVKALLGVLAPAEVSDAQIDDYV--AAYETPADDAGEEDAAA 114
>UniRef50_Q9X6X2 Cluster: Lipoamide acyltransferase; n=3;
Cystobacterineae|Rep: Lipoamide acyltransferase -
Myxococcus xanthus
Length = 416
Score = 44.8 bits (101), Expect = 0.002
Identities = 20/52 (38%), Positives = 28/52 (53%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAK 446
LP L + G +V W K GD + E +L E+ TDKAT+ P+ G + K
Sbjct: 8 LPDLGEGVMEGELVKWHVKAGDSVKEDQVLAEVMTDKATVTVPAPKAGRVVK 59
>UniRef50_Q057P2 Cluster: 2-oxoglutarate dehydrogenase E2 component;
n=1; Buchnera aphidicola str. Cc (Cinara cedri)|Rep:
2-oxoglutarate dehydrogenase E2 component - Buchnera
aphidicola subsp. Cinara cedri
Length = 398
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/63 (33%), Positives = 33/63 (52%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
K+ P L ++ ++ W KK GD + E +++ EIETDK + +P+ G L I
Sbjct: 6 KILAPNLPESVNHAIMLKWNKKIGDYVKEDEIIAEIETDKIILEISSPKNGILISQNILV 65
Query: 462 GTK 470
G K
Sbjct: 66 GEK 68
>UniRef50_P0AFG7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=24; Enterobacteriaceae|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Escherichia coli O157:H7
Length = 405
Score = 44.8 bits (101), Expect = 0.002
Identities = 20/65 (30%), Positives = 34/65 (52%)
Frame = +3
Query: 273 SHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKIL 452
S + + +P L ++ ++ +W KK GD + ++L EIETDK + +G L +L
Sbjct: 2 SSVDILVPDLPESVADATVATWHKKPGDAVVRDEVLVEIETDKVVLEVPASADGILDAVL 61
Query: 453 IPAGT 467
GT
Sbjct: 62 EDEGT 66
>UniRef50_Q8DFQ0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide acyltransferase component;
n=17; Bacteria|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
component - Vibrio vulnificus
Length = 402
Score = 44.4 bits (100), Expect = 0.003
Identities = 19/62 (30%), Positives = 34/62 (54%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I++ +P L ++ ++ +W KK GD++ ++L +IETDK + E G L I+
Sbjct: 3 IEILVPDLPESVADATVATWHKKPGDRVERDEVLVDIETDKVVLEVPASEAGILEAIVEE 62
Query: 459 AG 464
G
Sbjct: 63 EG 64
>UniRef50_Q0SGE5 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=3; Actinomycetales|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 417
Score = 44.4 bits (100), Expect = 0.003
Identities = 22/65 (33%), Positives = 35/65 (53%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
LP L + +VSW + G + ++ E+ET KA + +P G + ++L+PAG
Sbjct: 7 LPDLGEGLTEAELVSWAVEVGQTIELNQVIGEVETAKALVELPSPYAGVVEELLVPAGAT 66
Query: 471 GVPVG 485
VPVG
Sbjct: 67 -VPVG 70
>UniRef50_A5V538 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Sphingomonas wittichii
RW1|Rep: Catalytic domain of components of various
dehydrogenase complexes - Sphingomonas wittichii RW1
Length = 396
Score = 44.4 bits (100), Expect = 0.003
Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 3/67 (4%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
+P L TM G I W+ G+ +S G +L +ETDK + E P +G + +L G
Sbjct: 15 MPKLGLTMAEGLIAEWKVAPGEAVSAGQVLFVVETDKISNEIEAPADGTILSLLAEEGAT 74
Query: 471 ---GVPV 482
G PV
Sbjct: 75 VAVGAPV 81
>UniRef50_Q9RXQ3 Cluster: Pyruvate dehydrogenase complex,
dihydrolipoamide acetyltransferase E2 component; n=4;
Deinococci|Rep: Pyruvate dehydrogenase complex,
dihydrolipoamide acetyltransferase E2 component -
Deinococcus radiodurans
Length = 617
Score = 44.0 bits (99), Expect = 0.004
Identities = 23/76 (30%), Positives = 39/76 (51%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
+V LP + +E G++V+ GD +SEG + E+ETDKA + G + + +
Sbjct: 183 QVTLPDVGDNIEKGTVVTILVNVGDTVSEGQPVIELETDKAVVEVPANASGTVQSVAVKI 242
Query: 462 GTKGVPVGKLLCIIVG 509
G +PVG + + G
Sbjct: 243 G-DSIPVGGTILTLSG 257
Score = 43.6 bits (98), Expect = 0.006
Identities = 22/76 (28%), Positives = 40/76 (52%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
++ LP + +E G++V+ GD ++EG + EIETDKA + G + + +
Sbjct: 27 ELKLPDVGDNIEKGTVVTVLVNPGDSVTEGQPIIEIETDKAVVEVPASAAGTIEAVNVKV 86
Query: 462 GTKGVPVGKLLCIIVG 509
G +PVG ++ + G
Sbjct: 87 GDT-IPVGGVIATLGG 101
>UniRef50_A3HTS0 Cluster: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein; n=2; Bacteroidetes|Rep:
2-oxo acid dehydrogenases acyltransferase (Catalytic
domain) protein - Algoriphagus sp. PR1
Length = 432
Score = 44.0 bits (99), Expect = 0.004
Identities = 23/75 (30%), Positives = 39/75 (52%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
+++ +P + ++ G+I+ W KKEG+ + + + + E+ TDK G L KIL
Sbjct: 4 VEMLMPKMGESIIEGTILGWLKKEGETIEQDESVLEVATDKVDTEVPATHPGVLKKILAK 63
Query: 459 AGTKGVPVGKLLCII 503
G V VG + II
Sbjct: 64 EGDV-VAVGAPIAII 77
>UniRef50_Q9VXY3 Cluster: CG5599-PA; n=4; Diptera|Rep: CG5599-PA -
Drosophila melanogaster (Fruit fly)
Length = 462
Score = 44.0 bits (99), Expect = 0.004
Identities = 20/63 (31%), Positives = 35/63 (55%)
Frame = +3
Query: 261 SSLPSHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYL 440
SSL + NL + + ++ W KEGD + + D LCE+++DKA++ + +G +
Sbjct: 33 SSLDKTVSFNLSDIGEGIREVTVKEWFVKEGDTVEQFDNLCEVQSDKASVTITSRYDGKI 92
Query: 441 AKI 449
KI
Sbjct: 93 TKI 95
>UniRef50_Q9I1M0 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex (EC
2.3.1.168) (Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase); n=22; Proteobacteria|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
(Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase) - Pseudomonas aeruginosa
Length = 428
Score = 44.0 bits (99), Expect = 0.004
Identities = 27/104 (25%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Frame = +3
Query: 273 SHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKIL 452
+H+ + +P + + +V W + GD ++E +L E+ TDKAT+ +P G + +
Sbjct: 3 THV-IKMPDIGEGIAEVELVEWHVQVGDSVNEDQVLAEVMTDKATVEIPSPVAGRILALG 61
Query: 453 IPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSP--ATPQKP 578
G G+L+ + V ++A ++P ATP+KP
Sbjct: 62 GQPGQVMAVGGELIRLEVEGAGNLAESPAAATPAAPVAATPEKP 105
>UniRef50_Q98ED1 Cluster: Dihydrolipoamide succinyl transferase;
n=8; Bacteria|Rep: Dihydrolipoamide succinyl transferase
- Rhizobium loti (Mesorhizobium loti)
Length = 424
Score = 43.6 bits (98), Expect = 0.006
Identities = 24/71 (33%), Positives = 38/71 (53%)
Frame = +3
Query: 282 KVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPA 461
++ +P L ++ +I W KK GD ++ + L E+ETDK T+ G L +I+
Sbjct: 4 EIRVPTLGESVTEATIGKWFKKVGDAIAVDEPLVELETDKVTVEVPAAAAGTLGEIVAKE 63
Query: 462 GTKGVPVGKLL 494
G + V VG LL
Sbjct: 64 G-ETVGVGALL 73
>UniRef50_A3UGB6 Cluster: Dihydrolipoamide acetyltransferase; n=2;
Alphaproteobacteria|Rep: Dihydrolipoamide
acetyltransferase - Oceanicaulis alexandrii HTCC2633
Length = 437
Score = 43.6 bits (98), Expect = 0.006
Identities = 30/107 (28%), Positives = 49/107 (45%)
Frame = +3
Query: 273 SHIKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKIL 452
S K LP + + IV W K GDK++E + ++ TDKAT+ G + I+
Sbjct: 2 SEYKYKLPDVGEGVVEAEIVEWHIKAGDKVTEDQHILDVMTDKATVEIPCAVNGVVKSIV 61
Query: 453 IPAGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQDK 593
G + + VG + +I D +V D ++ + P T P + K
Sbjct: 62 GEPG-EVIAVGTEILVIDVD-GEVP--DDVENTAEPETKDAPKEESK 104
>UniRef50_A0LLM2 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: Catalytic domain of components of
various dehydrogenase complexes - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 443
Score = 43.6 bits (98), Expect = 0.006
Identities = 30/92 (32%), Positives = 43/92 (46%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
++ LP L + G IV GD++ +G + IETDKAT P G + +I +
Sbjct: 3 VEFRLPDLGEGIHEGEIVEVLVSVGDRVLDGQPVMVIETDKATTEVPAPVSGVVKEIRVK 62
Query: 459 AGTKGVPVGKLLCIIVGDQNDVAAFKDFKDDS 554
G + V VG +L + VAA KD S
Sbjct: 63 PG-EVVKVGAVLMTFEAEGRAVAAAPPEKDVS 93
>UniRef50_A7AMV7 Cluster: Biotin-requiring enzyme family protein;
n=1; Babesia bovis|Rep: Biotin-requiring enzyme family
protein - Babesia bovis
Length = 177
Score = 43.6 bits (98), Expect = 0.006
Identities = 22/73 (30%), Positives = 39/73 (53%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +P + ++ I W K+ GD++ GDL+C +ETD+ + ++ G + + + G
Sbjct: 84 VKVPHIGRDVKHSKIQQWHKQRGDEVDVGDLICVLETDQVLVNVQSQLSGTIVETVGNEG 143
Query: 465 TKGVPVGKLLCII 503
+ V VG L II
Sbjct: 144 CR-VKVGADLIII 155
>UniRef50_Q9HN75 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Halobacterium salinarum|Rep: Dihydrolipoamide
S-acetyltransferase - Halobacterium salinarium
(Halobacterium halobium)
Length = 478
Score = 43.6 bits (98), Expect = 0.006
Identities = 28/88 (31%), Positives = 43/88 (48%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
LP + + G +V W EGD ++E + E+ETDKA + P +G + ++ G
Sbjct: 7 LPDVGEGVAEGELVRWLVDEGDTVTEDQPVAEVETDKAQVEVPAPVDGTVQELHWAEGDV 66
Query: 471 GVPVGKLLCIIVGDQNDVAAFKDFKDDS 554
VPVG L D + +A D D+S
Sbjct: 67 -VPVGDLFVTFDVD-GEASATADDGDES 92
>UniRef50_P57389 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=2; Enterobacteriaceae|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Buchnera aphidicola subsp. Acyrthosiphon pisum
(Acyrthosiphon pisumsymbiotic bacterium)
Length = 420
Score = 43.6 bits (98), Expect = 0.006
Identities = 21/62 (33%), Positives = 33/62 (53%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I + +P L ++ ++V W KK GD + D + +IETDK + +P +G L IL
Sbjct: 4 INILVPDLPESISDATVVKWHKKIGDTVHCDDNIVDIETDKVMLEVSSPCDGILQSILEK 63
Query: 459 AG 464
G
Sbjct: 64 EG 65
>UniRef50_Q67SE5 Cluster: Pyruvate dehydrogenase E2; n=1;
Symbiobacterium thermophilum|Rep: Pyruvate dehydrogenase
E2 - Symbiobacterium thermophilum
Length = 450
Score = 43.2 bits (97), Expect = 0.007
Identities = 18/54 (33%), Positives = 31/54 (57%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKIL 452
LP + + ++ W KEGD ++E + E++TDKAT+ +P G + K+L
Sbjct: 7 LPDVGEGLHEAELLRWLVKEGDTVTEDQPIMEVQTDKATVEITSPVNGRVVKLL 60
>UniRef50_A1FTV4 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Xanthomonadaceae|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Stenotrophomonas maltophilia R551-3
Length = 546
Score = 43.2 bits (97), Expect = 0.007
Identities = 26/77 (33%), Positives = 37/77 (48%)
Frame = +3
Query: 288 NLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGT 467
NLP L + +IV W KEGD + + L +ET KA + +P G + K+ AG
Sbjct: 92 NLPDLGEGLPDATIVEWFVKEGDVIKLDEPLVSMETAKAVVEVPSPFSGTVLKLSGAAGD 151
Query: 468 KGVPVGKLLCIIVGDQN 518
+P G +L D N
Sbjct: 152 I-IPTGSVLASFALDPN 167
>UniRef50_Q6ABX9 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=5; Actinomycetales|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Leifsonia xyli
subsp. xyli
Length = 452
Score = 43.2 bits (97), Expect = 0.007
Identities = 23/77 (29%), Positives = 41/77 (53%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
LP + + IVSW+ GD ++ ++ EIET K+ + +P EG + ++L+ G +
Sbjct: 8 LPDVGEGLTEAEIVSWKVAPGDSVAVNQVIVEIETAKSLVELPSPFEGTVGELLVVEG-Q 66
Query: 471 GVPVGKLLCIIVGDQND 521
V VG + + G + D
Sbjct: 67 TVEVGTPIFTVNGGEAD 83
>UniRef50_P35489 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=4; Acholeplasmataceae|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Acholeplasma
laidlawii
Length = 544
Score = 43.2 bits (97), Expect = 0.007
Identities = 24/91 (26%), Positives = 43/91 (47%)
Frame = +3
Query: 312 MESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTKGVPVGKL 491
+ G+++ W K GDK+ EG+ L +ETDK +P +G + + G + + VG++
Sbjct: 13 IHEGTVLQWNFKVGDKVKEGETLVIVETDKVNAELPSPVDGTIVSLGAKEGEE-IHVGQI 71
Query: 492 LCIIVGDQNDVAAFKDFKDDSSPATPQKPAS 584
+ + + D A S TP A+
Sbjct: 72 I-VTIDDGTGTPAAAPAPAQVSAPTPAPAAA 101
Score = 43.2 bits (97), Expect = 0.007
Identities = 26/90 (28%), Positives = 47/90 (52%)
Frame = +3
Query: 312 MESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTKGVPVGKL 491
+ G+I+ W K GDK+ EG+ L +ETDK +P +G + K L A + + VG+
Sbjct: 125 IHEGTILQWNFKVGDKVKEGETLVVVETDKVNAELPSPVDGTILK-LGKAEGEVIHVGET 183
Query: 492 LCIIVGDQNDVAAFKDFKDDSSPATPQKPA 581
+ +I + + + K ++ + P+K A
Sbjct: 184 VVLIGQNGATLEQAQAPKAEAPVSEPKKGA 213
>UniRef50_P19262 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor; n=21;
Ascomycota|Rep: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor -
Saccharomyces cerevisiae (Baker's yeast)
Length = 463
Score = 43.2 bits (97), Expect = 0.007
Identities = 29/119 (24%), Positives = 54/119 (45%), Gaps = 9/119 (7%)
Frame = +3
Query: 120 KKAIRSNITRCI-STELAKRKVTNKLLEHAQN-----QTVLSTPQWTVQMRYYSSLPSHI 281
K ++S + R + + KR + L + A LS + +V +S +
Sbjct: 12 KSLVKSKVARNVMAASFVKRHASTSLFKQANKVESLGSIYLSGKKISVAANPFSITSNRF 71
Query: 282 K---VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKI 449
K + +P ++ ++ GS+ + K GD + E +LL IETDK + +P G + K+
Sbjct: 72 KSTSIEVPPMAESLTEGSLKEYTKNVGDFIKEDELLATIETDKIDIEVNSPVSGTVTKL 130
>UniRef50_UPI0001555D03 Cluster: PREDICTED: similar to
2-oxoglutarate dehydrogenase complex subunit, putative,
partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
similar to 2-oxoglutarate dehydrogenase complex subunit,
putative, partial - Ornithorhynchus anatinus
Length = 163
Score = 42.7 bits (96), Expect = 0.010
Identities = 30/111 (27%), Positives = 52/111 (46%), Gaps = 2/111 (1%)
Frame = +3
Query: 237 WTVQMRYYSSLPSHIKV-NLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMG 413
WT + ++S+ I L + + ++ WEK+ GD + E D +C +++DKA +
Sbjct: 18 WTTRSFHHSAPRQAITTFKLCDIGEGISEVELIKWEKRIGDNVEEMDAVCTVQSDKAAVE 77
Query: 414 FETPEEGYLAKILIPAGTKGVPVG-KLLCIIVGDQNDVAAFKDFKDDSSPA 563
+ G + K+ + G + VG L+ I V D D A +SPA
Sbjct: 78 ISSRYTGIVKKLHVDVG-GFIKVGAPLMDIEVEDDEDDAKNVQAHIKASPA 127
>UniRef50_Q1IMV8 Cluster: Dihydrolipoamide acetyltransferase; n=1;
Acidobacteria bacterium Ellin345|Rep: Dihydrolipoamide
acetyltransferase - Acidobacteria bacterium (strain
Ellin345)
Length = 615
Score = 42.7 bits (96), Expect = 0.010
Identities = 30/101 (29%), Positives = 47/101 (46%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
LP L + SG +V K GD + EG + E+ETDKA + + G + ++ + G K
Sbjct: 7 LPELGENIASGDLVRVMVKPGDTVKEGQPVIELETDKAVIEVPSTVSGKVQEVKVQKGQK 66
Query: 471 GVPVGKLLCIIVGDQNDVAAFKDFKDDSSPATPQKPASQDK 593
+ VG I+ D AA + + T KP ++ K
Sbjct: 67 -LKVG----AIIFTYGDGAAAAPVQPAAPAKTEDKPKAEPK 102
Score = 39.5 bits (88), Expect = 0.092
Identities = 21/72 (29%), Positives = 38/72 (52%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
I+ LP L ++ G +V K+G +S+G + E+ETDKA + G + ++ +
Sbjct: 126 IEFKLPELGENIKQGQLVRIIAKQGASVSDGQPILELETDKAVIEVPATLTGTIKEVHVK 185
Query: 459 AGTKGVPVGKLL 494
G K + VG+ +
Sbjct: 186 EGDK-IGVGQTI 196
>UniRef50_Q7RIU5 Cluster: 2-oxoglutarate dehydrogenase, E2 component,
dihydrolipoamide succinyltransferase, putative; n=12;
cellular organisms|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase, putative
- Plasmodium yoelii yoelii
Length = 1632
Score = 42.7 bits (96), Expect = 0.010
Identities = 34/126 (26%), Positives = 55/126 (43%), Gaps = 7/126 (5%)
Frame = +3
Query: 147 RCISTELAKRKVTNKLLEHAQNQTVLSTPQWTVQMRY----YSSLPSHIKVN---LPALS 305
R I + ++K N + + N + + V+ R Y + H ++ +P L
Sbjct: 1204 RSIFESIFRKKSKNCIKQLIYNGNNVKRAFFNVEFRQLVNNYITCKRHFSIDTLKVPRLG 1263
Query: 306 PTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTKGVPVG 485
++ G I W+KK GD + + L I+TDK ++ + G L KI AG V V
Sbjct: 1264 DSITEGVINEWKKKVGDYVYSDETLAVIDTDKVSVDINSKSSGALHKIFAEAGDV-VLVD 1322
Query: 486 KLLCII 503
LC I
Sbjct: 1323 SPLCEI 1328
>UniRef50_Q6KH64 Cluster: Pyruvate dehydrogenase E3 component
dihydrolipoamide dehydrogenase; n=2; Bacteria|Rep:
Pyruvate dehydrogenase E3 component dihydrolipoamide
dehydrogenase - Mycoplasma mobile
Length = 600
Score = 42.3 bits (95), Expect = 0.013
Identities = 18/51 (35%), Positives = 27/51 (52%)
Frame = +3
Query: 312 MESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
+ G + KKEGD + EG+ L +ETDK T +P G + K+ + G
Sbjct: 13 LHEGLVAEIYKKEGDMVKEGEALFSVETDKVTSDIPSPATGKIVKVAMAQG 63
>UniRef50_Q5Z123 Cluster: Putative branched-chain alpha-keto acid
dehydrogenase component; n=1; Nocardia farcinica|Rep:
Putative branched-chain alpha-keto acid dehydrogenase
component - Nocardia farcinica
Length = 510
Score = 42.3 bits (95), Expect = 0.013
Identities = 24/78 (30%), Positives = 36/78 (46%)
Frame = +3
Query: 279 IKVNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIP 458
++ LP L + +VSW GD + + E+ET KA + P G +A +L
Sbjct: 8 LEFRLPDLGEGLTDAELVSWSVAVGDHVDLNQTIAEVETAKAVVALPCPYAGTVAALLAD 67
Query: 459 AGTKGVPVGKLLCIIVGD 512
G + VPVG L + D
Sbjct: 68 PG-ETVPVGAPLIRVRAD 84
>UniRef50_Q5KUY3 Cluster: Pyruvate dehydrogenase E2; n=2;
Geobacillus|Rep: Pyruvate dehydrogenase E2 - Geobacillus
kaustophilus
Length = 431
Score = 42.3 bits (95), Expect = 0.013
Identities = 22/71 (30%), Positives = 35/71 (49%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
LP + + I+ W +EGD + + EI+TDKA + TP G + + P G
Sbjct: 7 LPDIGEGLHEAEIIRWLVREGDVVKADQPIAEIQTDKAMVEMTTPVAGKVVALAGPEGAT 66
Query: 471 GVPVGKLLCII 503
V VG+ L ++
Sbjct: 67 -VKVGEPLIVV 76
>UniRef50_Q3JBP0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex dihydrolipoamide acyltransferase (E2) component
and related enzymes; n=1; Nitrosococcus oceani ATCC
19707|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex
dihydrolipoamide acyltransferase (E2) component and
related enzymes - Nitrosococcus oceani (strain ATCC
19707 / NCIMB 11848)
Length = 447
Score = 42.3 bits (95), Expect = 0.013
Identities = 30/103 (29%), Positives = 53/103 (51%), Gaps = 5/103 (4%)
Frame = +3
Query: 291 LPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTK 470
LP L +ESG + GD L + + E+ETDKA + + G + ++ + AG +
Sbjct: 7 LPELGENIESGDVAKVLVSPGDTLEKDQPVLELETDKAVVEIPSTASGKIKELKVKAGDQ 66
Query: 471 GVPVGKLLCIIV--GD--QNDV-AAFKDFKDDSSPATPQKPAS 584
V +G+++ + G+ Q DV AA ++ K + P+K A+
Sbjct: 67 -VAIGQVILTLEEGGEEAQEDVPAAREEPKPEQEHKPPEKSAA 108
>UniRef50_Q1IIF0 Cluster: Dihydrolipoamide S-succinyltransferase;
n=2; Acidobacteria|Rep: Dihydrolipoamide
S-succinyltransferase - Acidobacteria bacterium (strain
Ellin345)
Length = 555
Score = 42.3 bits (95), Expect = 0.013
Identities = 24/73 (32%), Positives = 37/73 (50%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +P + ++ G+I W K+ GD++ + L EI TDK P G L +I AG
Sbjct: 5 VIMPQMGESIFEGTITKWLKQPGDQVQRDEPLFEISTDKVDAEIPAPAAGILKEIKAQAG 64
Query: 465 TKGVPVGKLLCII 503
+ V V ++ II
Sbjct: 65 -QTVQVNTVVAII 76
Score = 41.9 bits (94), Expect = 0.017
Identities = 24/75 (32%), Positives = 36/75 (48%)
Frame = +3
Query: 285 VNLPALSPTMESGSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAG 464
V +P + ++ G+I W K GD + + L EI TDK P G L++I + AG
Sbjct: 125 VVMPQMGESIFEGTITKWLKNVGDTVQRDEPLFEISTDKVDAEIPAPVAGVLSEIKVQAG 184
Query: 465 TKGVPVGKLLCIIVG 509
V V ++ I G
Sbjct: 185 AT-VQVNTVVATIGG 198
>UniRef50_Q58628 Cluster: Pyruvate carboxylase subunit B; n=8;
cellular organisms|Rep: Pyruvate carboxylase subunit B -
Methanococcus jannaschii
Length = 567
Score = 42.3 bits (95), Expect = 0.013
Identities = 23/61 (37%), Positives = 35/61 (57%)
Frame = +3
Query: 321 GSIVSWEKKEGDKLSEGDLLCEIETDKATMGFETPEEGYLAKILIPAGTKGVPVGKLLCI 500
G + + KEGDK+ +GD++ +E K E+P EG + +ILI G V VG ++ I
Sbjct: 507 GMVTKIKVKEGDKVKKGDVIVVLEAMKMEHPIESPVEGTVERILIDEG-DAVNVGDVIMI 565
Query: 501 I 503
I
Sbjct: 566 I 566
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 714,241,090
Number of Sequences: 1657284
Number of extensions: 13593232
Number of successful extensions: 34667
Number of sequences better than 10.0: 381
Number of HSP's better than 10.0 without gapping: 33477
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 34634
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 65438977305
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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