BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= maV30064 (604 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q7PPW0 Cluster: ENSANGP00000000940; n=6; cellular organ... 233 2e-60 UniRef50_A1Z8L2 Cluster: CG30022-PA; n=7; Diptera|Rep: CG30022-P... 207 2e-52 UniRef50_O95571 Cluster: ETHE1 protein, mitochondrial precursor;... 200 2e-50 UniRef50_Q39B63 Cluster: Beta-lactamase-like; n=16; Proteobacter... 162 7e-39 UniRef50_A3M5E1 Cluster: Beta-lactamase-like protein; n=1; Acine... 151 9e-36 UniRef50_Q3J9M7 Cluster: Metallo-beta-lactamase family protein; ... 149 5e-35 UniRef50_A3Z5B4 Cluster: Beta-lactamase-like; n=2; Synechococcus... 147 2e-34 UniRef50_Q4FRC2 Cluster: Possible Beta-lactamase-like superfamil... 138 7e-32 UniRef50_Q89VN8 Cluster: Bll1007 protein; n=15; Proteobacteria|R... 137 2e-31 UniRef50_Q31H45 Cluster: Metallo-beta-lactamase superfamily prot... 137 2e-31 UniRef50_A0Q7P5 Cluster: Zn-dependent hydrolase; n=15; Gammaprot... 137 2e-31 UniRef50_A1AX88 Cluster: Beta-lactamase domain protein; n=1; Can... 136 4e-31 UniRef50_Q2JKB1 Cluster: Metallo-beta-lactamase domain protein; ... 130 2e-29 UniRef50_Q121S4 Cluster: Beta-lactamase-like; n=1; Polaromonas s... 103 4e-21 UniRef50_A6PAH2 Cluster: Beta-lactamase domain protein; n=1; She... 91 1e-17 UniRef50_Q1NKM3 Cluster: Beta-lactamase-like; n=3; Deltaproteoba... 88 2e-16 UniRef50_Q1FHG0 Cluster: Beta-lactamase-like; n=1; Clostridium p... 87 3e-16 UniRef50_A5ZNH8 Cluster: Putative uncharacterized protein; n=1; ... 85 1e-15 UniRef50_Q2LRW6 Cluster: Hydroxyacylglutathione hydrolase W; n=1... 84 3e-15 UniRef50_A0LJ17 Cluster: Beta-lactamase domain protein; n=1; Syn... 81 2e-14 UniRef50_A0RY05 Cluster: Zn-dependent hydrolase; n=2; Thermoprot... 81 2e-14 UniRef50_A5G5N2 Cluster: Beta-lactamase domain protein precursor... 80 3e-14 UniRef50_Q6MNF6 Cluster: Metallo-beta-lactamase superfamily prot... 80 5e-14 UniRef50_Q0SRP5 Cluster: Metallo-beta-lactamase family protein; ... 79 6e-14 UniRef50_A1IE49 Cluster: Hydroxyacylglutathione hydrolase W; n=1... 79 6e-14 UniRef50_Q1IQE8 Cluster: Beta-lactamase-like; n=2; Acidobacteria... 79 8e-14 UniRef50_A5EXZ6 Cluster: Metallo-beta-lactamase superfamily prot... 79 8e-14 UniRef50_Q64UQ6 Cluster: Putative metallo-beta-lactamase; n=5; B... 79 1e-13 UniRef50_Q1ZAD4 Cluster: Probable metallo-beta-lactamase superfa... 79 1e-13 UniRef50_Q892B0 Cluster: Hydroxyacylglutathione hydrolase; n=3; ... 78 1e-13 UniRef50_Q74E41 Cluster: Metallo-beta-lactamase family protein; ... 78 1e-13 UniRef50_A6G5S2 Cluster: Metallo-beta-lactamase family protein; ... 78 1e-13 UniRef50_A6DU41 Cluster: Metallo-beta-lactamase family protein; ... 78 1e-13 UniRef50_Q8RAL6 Cluster: Zn-dependent hydrolases, including glyo... 78 2e-13 UniRef50_A6L4P4 Cluster: Putative metallo-beta-lactamase; n=2; B... 78 2e-13 UniRef50_Q1PVC6 Cluster: Similar to hydroxyacylglutathione hydro... 77 2e-13 UniRef50_A3SZ22 Cluster: Beta-lactamase-like; n=6; Proteobacteri... 77 2e-13 UniRef50_A0LFG7 Cluster: Beta-lactamase domain protein; n=1; Syn... 77 4e-13 UniRef50_A1VR45 Cluster: Beta-lactamase domain protein; n=1; Pol... 75 1e-12 UniRef50_A6L981 Cluster: Metallo-beta-lactamase family protein; ... 75 1e-12 UniRef50_Q7MV11 Cluster: Metallo-beta-lactamase family protein; ... 74 3e-12 UniRef50_A4AWZ7 Cluster: Putative uncharacterized protein; n=2; ... 73 4e-12 UniRef50_Q57544 Cluster: Uncharacterized protein HI1663; n=20; P... 73 4e-12 UniRef50_Q314Q9 Cluster: Metallo-beta-lactamase family protein; ... 73 5e-12 UniRef50_Q08R44 Cluster: Myofibrillogenesis regulator 1; n=3; Cy... 73 5e-12 UniRef50_A6EK80 Cluster: Metallo-beta-lactamase family protein; ... 73 5e-12 UniRef50_A4C5I4 Cluster: Beta-lactamase-like protein; n=1; Pseud... 73 5e-12 UniRef50_Q191B3 Cluster: Beta-lactamase-like; n=3; Firmicutes|Re... 73 7e-12 UniRef50_A3IFE3 Cluster: YqgX; n=1; Bacillus sp. B14905|Rep: Yqg... 73 7e-12 UniRef50_Q97GU3 Cluster: Predicted Zn-dependent hydrolase of met... 72 9e-12 UniRef50_A3ZW37 Cluster: Putative uncharacterized protein; n=1; ... 72 9e-12 UniRef50_A4J2H1 Cluster: Beta-lactamase domain protein; n=2; Bac... 72 1e-11 UniRef50_A7C2X6 Cluster: Metallo-beta-lactamase family protein; ... 71 2e-11 UniRef50_A5KQ31 Cluster: Putative uncharacterized protein; n=3; ... 71 2e-11 UniRef50_Q0W1G4 Cluster: Putative metallo-beta-lactamase; n=1; u... 71 2e-11 UniRef50_P54501 Cluster: Uncharacterized protein yqgX; n=10; Bac... 71 2e-11 UniRef50_Q9JXH3 Cluster: Glyoxalase II family protein; n=5; Prot... 71 3e-11 UniRef50_Q39KM6 Cluster: Beta-lactamase-like; n=36; Proteobacter... 70 4e-11 UniRef50_A3DF45 Cluster: Beta-lactamase-like protein; n=1; Clost... 70 4e-11 UniRef50_A6PUJ8 Cluster: Beta-lactamase domain protein; n=1; Vic... 69 6e-11 UniRef50_Q54EJ5 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 69 6e-11 UniRef50_A1ID45 Cluster: Beta-lactamase-like; n=3; Bacteria|Rep:... 69 9e-11 UniRef50_Q39ZZ6 Cluster: Metallo-beta-lactamase family protein; ... 69 1e-10 UniRef50_A5FR77 Cluster: Beta-lactamase domain protein; n=3; Deh... 69 1e-10 UniRef50_A0UYT0 Cluster: Beta-lactamase-like; n=1; Clostridium c... 69 1e-10 UniRef50_Q9PFB0 Cluster: Beta-lactamase hydrolase-like protein; ... 69 1e-10 UniRef50_Q9AAS7 Cluster: Hydroxyacylglutathione hydrolase, putat... 68 1e-10 UniRef50_Q8EQ13 Cluster: Hypothetical conserved protein; n=1; Oc... 68 1e-10 UniRef50_Q81LX4 Cluster: Metallo-beta-lactamase family protein; ... 68 1e-10 UniRef50_Q15XB6 Cluster: Beta-lactamase-like; n=1; Pseudoalterom... 68 1e-10 UniRef50_A6DNT9 Cluster: Beta-lactamase-like protein; n=1; Lenti... 68 1e-10 UniRef50_Q1AWY9 Cluster: Beta-lactamase-like protein; n=1; Rubro... 68 2e-10 UniRef50_Q11FA6 Cluster: Beta-lactamase-like; n=121; Proteobacte... 68 2e-10 UniRef50_A6PMC1 Cluster: Beta-lactamase domain protein; n=1; Vic... 68 2e-10 UniRef50_A2FLV6 Cluster: Metallo-beta-lactamase superfamily prot... 68 2e-10 UniRef50_Q1MQL8 Cluster: Zn-dependent hydrolases, including glyo... 67 3e-10 UniRef50_A3M1P8 Cluster: Putative uncharacterized protein; n=1; ... 67 3e-10 UniRef50_Q940L0 Cluster: Glyoxalase II; n=9; Magnoliophyta|Rep: ... 67 3e-10 UniRef50_Q5XD24 Cluster: Uncharacterized protein M6_Spy0554; n=4... 67 3e-10 UniRef50_A5Z3V7 Cluster: Putative uncharacterized protein; n=1; ... 67 3e-10 UniRef50_Q5QUY0 Cluster: Zn-dependent hydrolases, glyoxylase fam... 66 6e-10 UniRef50_Q3A304 Cluster: Putative uncharacterized protein; n=1; ... 66 6e-10 UniRef50_Q2RHV9 Cluster: Beta-lactamase-like; n=3; Clostridia|Re... 66 6e-10 UniRef50_A6GG97 Cluster: Putative uncharacterized protein; n=1; ... 66 6e-10 UniRef50_A3I369 Cluster: Metallo-beta-lactamase family protein; ... 66 6e-10 UniRef50_A1UBD7 Cluster: Beta-lactamase domain protein; n=21; Ac... 66 6e-10 UniRef50_A0VLF2 Cluster: Hydroxyacylglutathione hydrolase; n=5; ... 66 6e-10 UniRef50_A6TQP1 Cluster: Beta-lactamase domain protein; n=2; Clo... 66 8e-10 UniRef50_A6TKP6 Cluster: Beta-lactamase domain protein; n=1; Alk... 66 8e-10 UniRef50_A0Z233 Cluster: Putative uncharacterized protein; n=3; ... 65 1e-09 UniRef50_A0HF94 Cluster: Beta-lactamase-like; n=6; cellular orga... 65 1e-09 UniRef50_Q8KAV6 Cluster: Hydroxyacylglutathione hydrolase, putat... 65 1e-09 UniRef50_Q8FYE7 Cluster: Hydroxyacylglutathione hydrolase, putat... 65 1e-09 UniRef50_P64261 Cluster: Uncharacterized protein Rv2581c/MT2658;... 65 1e-09 UniRef50_Q8N490 Cluster: Probable hydrolase PNKD; n=25; Euteleos... 64 2e-09 UniRef50_Q8N490-3 Cluster: Isoform 3 of Q8N490 ; n=8; Amniota|Re... 64 2e-09 UniRef50_A4XU09 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 64 2e-09 UniRef50_A7HGC5 Cluster: Beta-lactamase domain protein; n=2; Ana... 64 2e-09 UniRef50_A2DJY1 Cluster: Metallo-beta-lactamase superfamily prot... 64 2e-09 UniRef50_Q41FV9 Cluster: Beta-lactamase-like; n=1; Exiguobacteri... 64 3e-09 UniRef50_A7IG57 Cluster: Beta-lactamase domain protein; n=1; Xan... 64 3e-09 UniRef50_A7CUG8 Cluster: Beta-lactamase domain protein; n=1; Opi... 63 4e-09 UniRef50_Q97U88 Cluster: Putative uncharacterized protein; n=2; ... 63 4e-09 UniRef50_Q5FU83 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 63 6e-09 UniRef50_Q47LT8 Cluster: Putative hydrolase; n=1; Thermobifida f... 63 6e-09 UniRef50_Q5FRS6 Cluster: Metallo-beta-lactamase superfamily prot... 62 7e-09 UniRef50_Q183H6 Cluster: Putative hydrolase; n=2; Clostridium di... 62 7e-09 UniRef50_A4XI82 Cluster: Beta-lactamase domain protein; n=1; Cal... 62 7e-09 UniRef50_A1ZPC4 Cluster: Metallo-beta-lactamase family protein; ... 62 7e-09 UniRef50_UPI00015BCB57 Cluster: UPI00015BCB57 related cluster; n... 62 1e-08 UniRef50_Q0FEW8 Cluster: Putative hydroxyacylglutathione hydrola... 62 1e-08 UniRef50_A2R427 Cluster: Function: RSP29 precursor; n=20; Ascomy... 62 1e-08 UniRef50_Q7R4U1 Cluster: GLP_440_31929_31255; n=1; Giardia lambl... 61 2e-08 UniRef50_O94250 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 61 2e-08 UniRef50_Q60BX0 Cluster: Metallo-beta-lactamase family protein; ... 61 2e-08 UniRef50_A5WFB5 Cluster: Hydroxyacylglutathione hydrolase; n=3; ... 61 2e-08 UniRef50_Q54MR1 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 61 2e-08 UniRef50_Q3IR18 Cluster: Homolog 4 to thiosulfate sulfurtransfer... 61 2e-08 UniRef50_Q99KB8 Cluster: Hydroxyacylglutathione hydrolase; n=35;... 61 2e-08 UniRef50_Q82XW0 Cluster: Metallo-beta-lactamase superfamily; n=1... 60 3e-08 UniRef50_Q6F9P0 Cluster: Putative hydroxyacylglutathione hydrola... 60 4e-08 UniRef50_Q2S0T9 Cluster: Metallo-beta-lactamase family protein; ... 60 4e-08 UniRef50_A2DXP6 Cluster: Metallo-beta-lactamase superfamily prot... 60 4e-08 UniRef50_Q2SAD4 Cluster: Zn-dependent Hydrolase, including glyox... 60 5e-08 UniRef50_Q10LW8 Cluster: Hydroxyacylglutathione hydrolase, putat... 60 5e-08 UniRef50_Q1IW29 Cluster: Beta-lactamase-like protein; n=4; Deino... 59 7e-08 UniRef50_A6FTG4 Cluster: Beta-lactamase-like protein; n=1; Roseo... 59 7e-08 UniRef50_Q9XXJ1 Cluster: Putative uncharacterized protein; n=2; ... 59 7e-08 UniRef50_Q9UT36 Cluster: Hydroxyacylglutathione hydrolase; n=10;... 59 7e-08 UniRef50_O67893 Cluster: Uncharacterized protein aq_2135; n=1; A... 59 7e-08 UniRef50_A3CXZ9 Cluster: Beta-lactamase domain protein; n=1; Met... 59 9e-08 UniRef50_Q9HQ50 Cluster: Flavoprotein; n=4; Halobacteriaceae|Rep... 58 1e-07 UniRef50_UPI000049880A Cluster: metallo-beta-lactamase superfami... 58 2e-07 UniRef50_Q0G3G4 Cluster: Putative uncharacterized protein; n=1; ... 58 2e-07 UniRef50_Q1HQH9 Cluster: Glyoxylase 3; n=3; Endopterygota|Rep: G... 58 2e-07 UniRef50_Q5HP04 Cluster: Metallo-beta-lactamase family protein; ... 58 2e-07 UniRef50_P75849 Cluster: Uncharacterized protein ycbL; n=120; Ba... 58 2e-07 UniRef50_Q1D198 Cluster: Metallo-beta-lactamase family protein; ... 57 3e-07 UniRef50_UPI0000E49FBF Cluster: PREDICTED: hypothetical protein,... 54 4e-07 UniRef50_Q9A911 Cluster: Glyoxalase II family protein; n=21; Pro... 57 4e-07 UniRef50_Q89XT5 Cluster: Glyoxalase II; n=16; Alphaproteobacteri... 57 4e-07 UniRef50_Q73JL5 Cluster: Metallo-beta-lactamase family protein; ... 57 4e-07 UniRef50_Q2VZH9 Cluster: Zn-dependent hydrolase, including glyox... 57 4e-07 UniRef50_Q1GEU3 Cluster: Hydroxyacylglutathione hydrolase; n=9; ... 57 4e-07 UniRef50_A5WCY4 Cluster: Beta-lactamase domain protein; n=5; Pro... 57 4e-07 UniRef50_A3HIG2 Cluster: Beta-lactamase domain protein; n=18; Ga... 57 4e-07 UniRef50_A7DEZ8 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 56 5e-07 UniRef50_Q8Y5A2 Cluster: Lmo2167 protein; n=12; Listeria|Rep: Lm... 56 6e-07 UniRef50_Q5H3M1 Cluster: Beta-lactamase; n=8; Xanthomonadaceae|R... 56 6e-07 UniRef50_A5G655 Cluster: Beta-lactamase domain protein; n=1; Geo... 56 6e-07 UniRef50_A1AVZ9 Cluster: Beta-lactamase domain protein; n=2; sul... 56 6e-07 UniRef50_Q5J7B5 Cluster: Glyoxalase IIB; n=9; Plasmodium|Rep: Gl... 56 6e-07 UniRef50_UPI00006CD179 Cluster: metallo-beta-lactamase superfami... 56 9e-07 UniRef50_Q1PVA8 Cluster: Similar to hydroxyacylglutathione hydro... 56 9e-07 UniRef50_A0LDZ9 Cluster: Beta-lactamase domain protein; n=1; Mag... 56 9e-07 UniRef50_A2FNK4 Cluster: Metallo-beta-lactamase superfamily prot... 56 9e-07 UniRef50_Q9UZT9 Cluster: Hydroxyacylglutathione hydrolase relate... 56 9e-07 UniRef50_Q8TPW0 Cluster: Metallo-beta-lactamase; n=3; cellular o... 56 9e-07 UniRef50_A0B5Y5 Cluster: Beta-lactamase domain protein; n=1; Met... 56 9e-07 UniRef50_Q2LX15 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 55 1e-06 UniRef50_A7AQJ8 Cluster: Hydroxyacylglutathione hydrolase, putat... 55 1e-06 UniRef50_P0AC85 Cluster: Probable hydroxyacylglutathione hydrola... 55 1e-06 UniRef50_O24495 Cluster: Hydroxyacylglutathione hydrolase 1, mit... 55 1e-06 UniRef50_Q6MCN3 Cluster: Putative uncharacterized protein; n=1; ... 55 1e-06 UniRef50_Q1GVB7 Cluster: Hydroxyacylglutathione hydrolase precur... 55 1e-06 UniRef50_Q12BV7 Cluster: Hydroxyacylglutathione hydrolase; n=3; ... 55 1e-06 UniRef50_Q01Q87 Cluster: Beta-lactamase domain protein; n=1; Sol... 55 1e-06 UniRef50_A6G1T9 Cluster: Putative uncharacterized protein; n=1; ... 55 1e-06 UniRef50_Q8ZX02 Cluster: Conserved protein; n=4; Pyrobaculum|Rep... 55 1e-06 UniRef50_A3VUN8 Cluster: Hydrolase; n=5; Proteobacteria|Rep: Hyd... 54 2e-06 UniRef50_A0M126 Cluster: Metallo-beta-lactamase/rhodanese-like d... 54 2e-06 UniRef50_Q22PH1 Cluster: Metallo-beta-lactamase superfamily prot... 54 2e-06 UniRef50_O54661 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-06 UniRef50_Q8NQ06 Cluster: Zn-dependent hydrolases, including glyo... 54 3e-06 UniRef50_Q8D376 Cluster: YcbL protein; n=1; Wigglesworthia gloss... 54 3e-06 UniRef50_Q1V0X4 Cluster: Hydroxyacylglutathione hydrolase cytopl... 54 3e-06 UniRef50_A0R0C8 Cluster: Metallo-beta-lactamase family protein; ... 54 3e-06 UniRef50_Q8TNG7 Cluster: Metallo-beta-lactamase; n=3; Methanosar... 54 3e-06 UniRef50_Q6ML19 Cluster: Hydroxyacylglutathione hydrolase GloB; ... 54 3e-06 UniRef50_A4IPS9 Cluster: Metallo-beta-lactamase family protein; ... 54 3e-06 UniRef50_A3WQ55 Cluster: Probable hydroxyacylglutathione hydrola... 54 3e-06 UniRef50_Q22YX3 Cluster: Metallo-beta-lactamase superfamily prot... 54 3e-06 UniRef50_A6NCC4 Cluster: Uncharacterized protein HAGHL; n=24; Eu... 54 3e-06 UniRef50_Q5KIL7 Cluster: Hydroxyacylglutathione hydrolase, putat... 54 3e-06 UniRef50_UPI0000E244B7 Cluster: PREDICTED: similar to glyoxalase... 53 5e-06 UniRef50_A0DS29 Cluster: Chromosome undetermined scaffold_61, wh... 53 5e-06 UniRef50_Q16775 Cluster: Hydroxyacylglutathione hydrolase; n=15;... 53 5e-06 UniRef50_UPI0000F2E09A Cluster: PREDICTED: similar to myofibrill... 53 6e-06 UniRef50_Q4JWL1 Cluster: Putative uncharacterized protein; n=1; ... 53 6e-06 UniRef50_A6FA17 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 53 6e-06 UniRef50_A4VLR2 Cluster: Hydroxyacylglutathione hydrolase; n=4; ... 53 6e-06 UniRef50_A4E7W3 Cluster: Putative uncharacterized protein; n=1; ... 53 6e-06 UniRef50_UPI0000DAE586 Cluster: hypothetical protein Rgryl_01000... 52 8e-06 UniRef50_Q8REE5 Cluster: Hydroxyacylglutathione hydrolase; n=3; ... 52 8e-06 UniRef50_Q89VZ3 Cluster: Bll0900 protein; n=9; Rhizobiales|Rep: ... 52 1e-05 UniRef50_Q1RS81 Cluster: Hydroxyacylglutathione hydrolase; n=3; ... 52 1e-05 UniRef50_Q04RQ6 Cluster: Zn-dependent hydrolase; n=3; Leptospira... 52 1e-05 UniRef50_Q9YCJ7 Cluster: Putative uncharacterized protein; n=1; ... 52 1e-05 UniRef50_A7D114 Cluster: Beta-lactamase domain protein; n=4; Hal... 52 1e-05 UniRef50_Q2LSA2 Cluster: Zn-dependent hydrolases; n=1; Syntrophu... 52 1e-05 UniRef50_Q1K398 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 52 1e-05 UniRef50_A4W8U6 Cluster: Beta-lactamase domain protein; n=11; Ga... 52 1e-05 UniRef50_Q4PH24 Cluster: Putative uncharacterized protein; n=1; ... 52 1e-05 UniRef50_Q4JCD2 Cluster: Conserved protein; n=1; Sulfolobus acid... 52 1e-05 UniRef50_Q488C8 Cluster: Aminotransferase, class V; n=5; Alterom... 51 2e-05 UniRef50_A6LR94 Cluster: Beta-lactamase domain protein; n=1; Clo... 51 2e-05 UniRef50_A0YF48 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 51 2e-05 UniRef50_Q4QBB0 Cluster: Metallo-beta-lactamase family protein-l... 51 2e-05 UniRef50_A5V0A4 Cluster: Beta-lactamase domain protein; n=2; Ros... 51 2e-05 UniRef50_A7RVP5 Cluster: Predicted protein; n=1; Nematostella ve... 51 2e-05 UniRef50_Q2BJ10 Cluster: Metallo-beta-lactamase superfamily prot... 50 3e-05 UniRef50_Q3WFW5 Cluster: Beta-lactamase-like; n=1; Frankia sp. E... 50 3e-05 UniRef50_A6VVZ9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 50 3e-05 UniRef50_A3UF19 Cluster: Metallo-beta-lactamase family protein; ... 50 3e-05 UniRef50_P95849 Cluster: Orf c06001 protein; n=2; Sulfolobus|Rep... 50 3e-05 UniRef50_A4C5I6 Cluster: Putative hydroxyacylglutathione hydrola... 50 4e-05 UniRef50_A4BIQ3 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 50 4e-05 UniRef50_A0NAW9 Cluster: ENSANGP00000031703; n=1; Anopheles gamb... 50 4e-05 UniRef50_Q6MFA0 Cluster: Putative uncharacterized protein; n=1; ... 50 6e-05 UniRef50_A6EE42 Cluster: Rhodanese-like protein; n=1; Pedobacter... 50 6e-05 UniRef50_A4IWV0 Cluster: Metallo-beta-lactamase superfamily prot... 50 6e-05 UniRef50_A3Q4D8 Cluster: Beta-lactamase domain protein; n=8; Act... 50 6e-05 UniRef50_A2BQ40 Cluster: Putative hydroxyacylglutathione hydrola... 50 6e-05 UniRef50_A0LJP1 Cluster: Beta-lactamase domain protein; n=1; Syn... 50 6e-05 UniRef50_A0LFL1 Cluster: Beta-lactamase domain protein; n=1; Syn... 50 6e-05 UniRef50_Q7VR07 Cluster: Zn-dependent hydrolase; n=7; Gammaprote... 49 7e-05 UniRef50_Q1Q513 Cluster: Putative uncharacterized protein; n=1; ... 49 7e-05 UniRef50_Q0RV10 Cluster: Possible hydroxyacylglutathione hydrola... 49 7e-05 UniRef50_A1U0V1 Cluster: Hydroxyacylglutathione hydrolase; n=3; ... 49 7e-05 UniRef50_A1RAH8 Cluster: Metallo-beta-lactamase superfamily prot... 49 7e-05 UniRef50_A0L873 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 48 8e-05 UniRef50_Q125G3 Cluster: Beta-lactamase-like precursor; n=7; Bac... 49 1e-04 UniRef50_Q0LHZ1 Cluster: Beta-lactamase-like; n=1; Herpetosiphon... 49 1e-04 UniRef50_Q4UGN4 Cluster: Hydroxyacylglutathione hydrolase, putat... 49 1e-04 UniRef50_P57336 Cluster: Probable hydroxyacylglutathione hydrola... 49 1e-04 UniRef50_Q5HUY3 Cluster: Metallo-beta-lactamase family protein; ... 48 1e-04 UniRef50_A1SJB6 Cluster: Beta-lactamase domain protein; n=13; Ac... 48 1e-04 UniRef50_Q0W7P0 Cluster: Putative uncharacterized protein; n=1; ... 48 1e-04 UniRef50_P72933 Cluster: Probable hydroxyacylglutathione hydrola... 48 1e-04 UniRef50_Q7VQB7 Cluster: Probable hydroxyacylglutathione hydrola... 48 2e-04 UniRef50_Q2LPQ6 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 48 2e-04 UniRef50_A0UWD4 Cluster: Beta-lactamase-like; n=1; Clostridium c... 48 2e-04 UniRef50_A0DY50 Cluster: Chromosome undetermined scaffold_7, who... 48 2e-04 UniRef50_Q5AXZ0 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04 UniRef50_Q2H306 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04 UniRef50_A5DYF9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 48 2e-04 UniRef50_UPI0000E23FD0 Cluster: PREDICTED: hydroxyacylglutathion... 48 2e-04 UniRef50_A6FY39 Cluster: Probable hydroxyacylglutathione hydrola... 48 2e-04 UniRef50_A4AQV7 Cluster: Metallo-beta-lactamase superfamily prot... 48 2e-04 UniRef50_A1WFG7 Cluster: Hydroxyacylglutathione hydrolase precur... 48 2e-04 UniRef50_A1SS88 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 48 2e-04 UniRef50_Q7QZA0 Cluster: GLP_567_43928_43275; n=1; Giardia lambl... 48 2e-04 UniRef50_Q89AN4 Cluster: Probable hydroxyacylglutathione hydrola... 48 2e-04 UniRef50_Q483N7 Cluster: Metallo-beta-lactamase family protein; ... 47 3e-04 UniRef50_Q0RV06 Cluster: Possible hydrolase; n=11; Actinomycetal... 47 3e-04 UniRef50_Q031I9 Cluster: Zn-dependent hydrolase, including glyox... 47 3e-04 UniRef50_A3I4E3 Cluster: Possible Zn-dependent hydrolase, beta-l... 47 3e-04 UniRef50_A4YDP4 Cluster: Beta-lactamase domain protein; n=1; Met... 47 3e-04 UniRef50_Q7MUF5 Cluster: Metallo-beta-lactamase superfamily prot... 47 4e-04 UniRef50_Q2W813 Cluster: Zn-dependent hydrolase; n=3; Magnetospi... 47 4e-04 UniRef50_Q2SJ47 Cluster: Zn-dependent Hydrolase, including glyox... 47 4e-04 UniRef50_A6NSY9 Cluster: Putative uncharacterized protein; n=1; ... 47 4e-04 UniRef50_A0WBI6 Cluster: Beta-lactamase-like; n=1; Geobacter lov... 47 4e-04 UniRef50_A0JR39 Cluster: Beta-lactamase domain protein; n=11; Ac... 47 4e-04 UniRef50_Q2NGP4 Cluster: Predicted Zn-dependent hydrolase; n=1; ... 47 4e-04 UniRef50_O29680 Cluster: Putative uncharacterized protein; n=1; ... 47 4e-04 UniRef50_P96981 Cluster: Probable hydroxyacylglutathione hydrola... 47 4e-04 UniRef50_UPI000050F771 Cluster: COG0491: Zn-dependent hydrolases... 46 5e-04 UniRef50_Q5LNN5 Cluster: Hydroxyacylglutathione hydrolase, putat... 46 5e-04 UniRef50_Q4JW14 Cluster: Putative uncharacterized protein; n=1; ... 46 5e-04 UniRef50_Q3IKH5 Cluster: Putative enzyme of the cysteine desulfu... 46 5e-04 UniRef50_Q1LZ83 Cluster: Similar to lactamase, beta 2; n=2; Bos ... 46 5e-04 UniRef50_Q236K6 Cluster: Metallo-beta-lactamase superfamily prot... 46 5e-04 UniRef50_Q8SSH0 Cluster: HYDROXYACYL GLUTATHION HYDROLASE; n=1; ... 46 5e-04 UniRef50_Q2S5Q9 Cluster: Metallo-beta-lactamase superfamily prot... 46 7e-04 UniRef50_A5FZE9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 46 7e-04 UniRef50_A1R963 Cluster: Metallo-beta-lactamase superfamily prot... 46 7e-04 UniRef50_A4FI79 Cluster: Metallo-beta-lactamase; n=3; Actinomyce... 46 0.001 UniRef50_A5YSG8 Cluster: Thiosulfate sulfurtransferase/hydrolase... 46 0.001 UniRef50_A0Z1L0 Cluster: NUDIX hydrolase:Beta-lactamase-like pro... 45 0.001 UniRef50_Q8TUW9 Cluster: Zn-dependent hydrolase; n=1; Methanopyr... 45 0.001 UniRef50_A2SPW9 Cluster: Beta-lactamase domain protein; n=1; Met... 45 0.001 UniRef50_A7D422 Cluster: Beta-lactamase domain protein; n=2; Hal... 37 0.002 UniRef50_Q6A9K5 Cluster: Zn-dependent hydrolase; n=1; Propioniba... 45 0.002 UniRef50_Q0RV20 Cluster: Possible hydrolase; n=1; Rhodococcus sp... 45 0.002 UniRef50_A6CFG1 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002 UniRef50_A5UWV7 Cluster: Beta-lactamase domain protein; n=2; Ros... 45 0.002 UniRef50_A0K1H6 Cluster: Beta-lactamase domain protein; n=5; Act... 45 0.002 UniRef50_A0H241 Cluster: Beta-lactamase-like; n=2; Chloroflexus|... 45 0.002 UniRef50_Q9Y392 Cluster: CGI-83 protein; n=24; Coelomata|Rep: CG... 45 0.002 UniRef50_A3CRI7 Cluster: Beta-lactamase domain protein; n=3; Met... 45 0.002 UniRef50_Q1AUZ4 Cluster: Beta-lactamase-like protein; n=1; Rubro... 44 0.002 UniRef50_Q0HI83 Cluster: Hydroxyacylglutathione hydrolase; n=5; ... 44 0.002 UniRef50_Q2JD17 Cluster: Beta-lactamase-like; n=37; Actinomyceta... 44 0.003 UniRef50_P71374 Cluster: Probable hydroxyacylglutathione hydrola... 44 0.003 UniRef50_Q8YZ99 Cluster: All0580 protein; n=6; Cyanobacteria|Rep... 44 0.004 UniRef50_Q47FN7 Cluster: Beta-lactamase-like; n=1; Dechloromonas... 44 0.004 UniRef50_Q1AVJ8 Cluster: Beta-lactamase-like protein; n=4; Bacte... 44 0.004 UniRef50_O30264 Cluster: Putative uncharacterized protein; n=1; ... 44 0.004 UniRef50_UPI0000E87C10 Cluster: putative hydroxyacylglutathione ... 43 0.005 UniRef50_UPI0000499269 Cluster: metallo-beta-lactamase superfami... 43 0.005 UniRef50_Q0VPW4 Cluster: Metallo-beta-lactamase family protein; ... 43 0.005 UniRef50_A6GS22 Cluster: Metallo-beta-lactamase family protein; ... 43 0.005 UniRef50_Q2FPN8 Cluster: Beta-lactamase-like; n=1; Methanospiril... 43 0.005 UniRef50_Q8NU87 Cluster: Zn-dependent hydrolases, including glyo... 43 0.006 UniRef50_Q31H51 Cluster: Metallo-beta-lactamase superfamily prot... 43 0.006 UniRef50_A6F4F3 Cluster: Zn-dependent hydrolase or glyoxylase,me... 43 0.006 UniRef50_A5IBE7 Cluster: Hydroxyacylglutathione hydrolase GloB; ... 43 0.006 UniRef50_A4G3L0 Cluster: Putative uncharacterized protein; n=1; ... 43 0.006 UniRef50_Q2UI96 Cluster: Zn-dependent hydrolases; n=4; Pezizomyc... 43 0.006 UniRef50_Q62DP8 Cluster: Metallo-beta-lactamase family protein; ... 42 0.008 UniRef50_A2QJI7 Cluster: Catalytic activity:; n=3; Aspergillus|R... 42 0.008 UniRef50_UPI00015978D7 Cluster: NrsD; n=1; Bacillus amyloliquefa... 42 0.011 UniRef50_UPI0000ECBE0D Cluster: ETHE1 protein, mitochondrial pre... 42 0.011 UniRef50_Q8F1D2 Cluster: Metallo-beta-lactamase superfamily prot... 42 0.011 UniRef50_Q01D52 Cluster: Glyoxylase; n=2; Ostreococcus|Rep: Glyo... 42 0.011 UniRef50_Q9PBI4 Cluster: Hydroxyacylglutathione hydrolase; n=9; ... 42 0.015 UniRef50_Q0G0G6 Cluster: Metallo-beta-lactamase family protein; ... 42 0.015 UniRef50_A0YBD1 Cluster: Metallo-beta-lactamase superfamily prot... 42 0.015 UniRef50_Q01BW2 Cluster: Glyoxylase; n=2; Ostreococcus|Rep: Glyo... 42 0.015 UniRef50_Q2J8G9 Cluster: Beta-lactamase-like; n=4; Frankia|Rep: ... 41 0.020 UniRef50_Q5UF41 Cluster: Predicted metallo-beta-lactamase family... 41 0.020 UniRef50_O28526 Cluster: Putative uncharacterized protein; n=1; ... 41 0.020 UniRef50_Q7VIV4 Cluster: Predicted hydrolase; n=4; Epsilonproteo... 41 0.026 UniRef50_Q4JVE7 Cluster: Putative uncharacterized protein; n=1; ... 41 0.026 UniRef50_Q2JCI6 Cluster: Beta-lactamase-like; n=33; Actinomyceta... 41 0.026 UniRef50_Q2LXM2 Cluster: Zn-dependent hydrolases, including glyo... 40 0.034 UniRef50_Q21J46 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 40 0.034 UniRef50_A7A5I2 Cluster: Putative uncharacterized protein; n=1; ... 40 0.034 UniRef50_UPI00006CA6B9 Cluster: Rhodanese-like domain containing... 40 0.045 UniRef50_Q8EE27 Cluster: Metallo-beta-lactamase family protein; ... 40 0.045 UniRef50_Q7VD23 Cluster: Metallo-beta-lactamase superfamily hydr... 40 0.045 UniRef50_Q749H4 Cluster: Metallo-beta-lactamase family protein; ... 40 0.045 UniRef50_Q01RD2 Cluster: Beta-lactamase precursor; n=1; Solibact... 40 0.045 UniRef50_A7CQ32 Cluster: Beta-lactamase domain protein; n=1; Opi... 40 0.045 UniRef50_A5USF6 Cluster: Beta-lactamase domain protein; n=3; Bac... 40 0.045 UniRef50_A1R7K8 Cluster: Metallo-beta-lactamase superfamily prot... 40 0.045 UniRef50_Q8D3D4 Cluster: GloB protein; n=1; Wigglesworthia gloss... 40 0.060 UniRef50_Q6NAT5 Cluster: Beta-lactamase-like; n=35; Alphaproteob... 40 0.060 UniRef50_Q0RIQ0 Cluster: Putative uncharacterized protein; n=1; ... 40 0.060 UniRef50_A0RPV5 Cluster: Metallo-beta-lactamase family protein; ... 40 0.060 UniRef50_Q9Y8P8 Cluster: Putative uncharacterized protein; n=1; ... 40 0.060 UniRef50_Q9HS22 Cluster: Putative uncharacterized protein; n=1; ... 40 0.060 UniRef50_Q5V0M3 Cluster: Putative uncharacterized protein; n=1; ... 40 0.060 UniRef50_O69645 Cluster: POSSIBLE HYDROLASE; n=30; Bacteria|Rep:... 39 0.079 UniRef50_A6BZ99 Cluster: Putative uncharacterized protein; n=2; ... 39 0.079 UniRef50_A4SXM4 Cluster: Hydroxyacylglutathione hydrolase precur... 39 0.079 UniRef50_Q1E6T3 Cluster: Putative uncharacterized protein; n=1; ... 39 0.079 UniRef50_Q9A9Q1 Cluster: Metallo-beta-lactamase family protein; ... 39 0.10 UniRef50_Q7MQ55 Cluster: Putative hydroxyacylglutathione hydrola... 39 0.10 UniRef50_Q6A8J8 Cluster: Metallo-beta-lactamase superfamily prot... 39 0.10 UniRef50_A7JRH0 Cluster: Hydroxyacylglutathione hydrolase; n=3; ... 39 0.10 UniRef50_A3IH33 Cluster: Hydrolase; n=1; Cyanothece sp. CCY 0110... 39 0.10 UniRef50_Q4D0L0 Cluster: Metallo-beta-lactamase-like protein, pu... 39 0.10 UniRef50_Q8THA3 Cluster: Metallo-beta-lactamase; n=5; Archaea|Re... 38 0.14 UniRef50_Q2HB61 Cluster: Putative uncharacterized protein; n=1; ... 38 0.18 UniRef50_Q9YFB1 Cluster: Putative uncharacterized protein; n=1; ... 38 0.18 UniRef50_UPI000050FB28 Cluster: COG0491: Zn-dependent hydrolases... 38 0.24 UniRef50_Q5YXI3 Cluster: Putative uncharacterized protein; n=3; ... 38 0.24 UniRef50_Q1N198 Cluster: Probable hydroxyacylglutathione hydrola... 38 0.24 UniRef50_Q0F0R2 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 38 0.24 UniRef50_A6LG49 Cluster: Putative uncharacterized protein; n=1; ... 38 0.24 UniRef50_A0LWF9 Cluster: Beta-lactamase domain protein; n=1; Aci... 38 0.24 UniRef50_Q4QGS1 Cluster: Hydroxyacylglutathione hydrolase, putat... 38 0.24 UniRef50_Q24F45 Cluster: Hydroxyacylglutathione hydrolase, putat... 38 0.24 UniRef50_Q12320 Cluster: Hydroxyacylglutathione hydrolase, mitoc... 38 0.24 UniRef50_Q0SG22 Cluster: Beta lactamase; n=1; Rhodococcus sp. RH... 37 0.32 UniRef50_Q0I8S8 Cluster: Metallo-beta-lactamase superfamily hydr... 37 0.32 UniRef50_A4YQA8 Cluster: Putative beta-lactamase; n=1; Bradyrhiz... 37 0.32 UniRef50_Q4WQZ6 Cluster: Metallo-beta-lactamase domain protein, ... 37 0.32 UniRef50_UPI000023EAC6 Cluster: hypothetical protein FG07959.1; ... 37 0.42 UniRef50_Q5UAZ9 Cluster: Hypothetical hydroxylase protein; n=1; ... 37 0.42 UniRef50_Q1VZM6 Cluster: Metallo-beta-lactamase superfamily prot... 37 0.42 UniRef50_A5INW0 Cluster: Beta-lactamase domain protein; n=30; St... 37 0.42 UniRef50_A4BRT9 Cluster: Smc1; n=1; Nitrococcus mobilis Nb-231|R... 37 0.42 UniRef50_A3VRC1 Cluster: Metallo-beta-lactamase family protein; ... 37 0.42 UniRef50_A5PJT0 Cluster: MGC152119 protein; n=17; Euteleostomi|R... 37 0.42 UniRef50_A7RLT0 Cluster: Predicted protein; n=1; Nematostella ve... 37 0.42 UniRef50_O29716 Cluster: Putative uncharacterized protein; n=1; ... 37 0.42 UniRef50_UPI000050FD95 Cluster: COG0491: Zn-dependent hydrolases... 36 0.56 UniRef50_Q8EN25 Cluster: Hypothetical conserved protein; n=1; Oc... 36 0.56 UniRef50_Q2NVG1 Cluster: Putative hydroxyacylglutathione hydrola... 36 0.56 UniRef50_Q0AY27 Cluster: Putative uncharacterized protein; n=1; ... 36 0.56 UniRef50_A7HBH3 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 36 0.56 UniRef50_A4ALM0 Cluster: Putative hydrolase; n=1; marine actinob... 36 0.56 UniRef50_A1ASA4 Cluster: Beta-lactamase domain protein; n=2; Bac... 36 0.56 UniRef50_A2WKC0 Cluster: Putative uncharacterized protein; n=4; ... 36 0.56 UniRef50_Q4W945 Cluster: Metallo-beta-lactamase domain protein; ... 36 0.56 UniRef50_Q0RHX0 Cluster: Putative uncharacterized protein; n=1; ... 36 0.74 UniRef50_A5URH7 Cluster: Beta-lactamase domain protein; n=4; Chl... 36 0.74 UniRef50_A5PEY5 Cluster: Putative uncharacterized protein; n=3; ... 36 0.74 UniRef50_Q2FPN7 Cluster: Beta-lactamase-like; n=1; Methanospiril... 36 0.74 UniRef50_A7I7Q8 Cluster: Beta-lactamase domain protein; n=1; Can... 36 0.74 UniRef50_Q46TQ6 Cluster: Beta-lactamase-like; n=1; Ralstonia eut... 36 0.97 UniRef50_Q0AZS8 Cluster: Putative uncharacterized protein; n=1; ... 36 0.97 UniRef50_A1WXD9 Cluster: Hydroxyacylglutathione hydrolase; n=2; ... 36 0.97 UniRef50_Q23CX3 Cluster: Metallo-beta-lactamase superfamily prot... 36 0.97 UniRef50_O27335 Cluster: Conserved protein; n=2; Methanobacteria... 36 0.97 UniRef50_Q895R7 Cluster: Putative uncharacterized protein; n=2; ... 35 1.3 UniRef50_Q82N31 Cluster: Putative metallo-beta-lactamase-like pr... 35 1.3 UniRef50_Q3E6L0 Cluster: Beta-lactamase-like:Rhodanese-like; n=2... 35 1.3 UniRef50_Q2U887 Cluster: Glyoxylase; n=2; Trichocomaceae|Rep: Gl... 35 1.3 UniRef50_A7I6D7 Cluster: Beta-lactamase domain protein; n=1; Can... 35 1.7 UniRef50_UPI00006CD0F1 Cluster: hypothetical protein TTHERM_0012... 34 2.3 UniRef50_UPI00003C0664 Cluster: PREDICTED: similar to CG12375-PA... 34 2.3 UniRef50_Q3SIB0 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 34 2.3 UniRef50_Q2G7J0 Cluster: Beta-lactamase-like protein precursor; ... 34 2.3 UniRef50_Q9K578 Cluster: FEZ-1 protein; n=1; Fluoribacter gorman... 34 2.3 UniRef50_Q1IJS0 Cluster: Beta-lactamase-like precursor; n=1; Aci... 34 2.3 UniRef50_Q0LPD2 Cluster: Beta-lactamase-like; n=1; Herpetosiphon... 34 2.3 UniRef50_A7RLS8 Cluster: Predicted protein; n=3; Nematostella ve... 34 2.3 UniRef50_Q18FM0 Cluster: Hydrolase; n=4; Halobacteriaceae|Rep: H... 34 2.3 UniRef50_Q4SBY0 Cluster: Chromosome 2 SCAF14661, whole genome sh... 34 3.0 UniRef50_Q8RE48 Cluster: Zinc metallohydrolase, glyoxalase II fa... 34 3.0 UniRef50_Q7UGS7 Cluster: Putative uncharacterized protein; n=3; ... 34 3.0 UniRef50_Q73QI1 Cluster: Metallo-beta-lactamase family protein; ... 34 3.0 UniRef50_Q6D395 Cluster: Metallo-beta-lactamase; n=1; Pectobacte... 34 3.0 UniRef50_Q18SX3 Cluster: Beta-lactamase-like; n=2; Desulfitobact... 34 3.0 UniRef50_Q0RVM2 Cluster: Putative uncharacterized protein; n=1; ... 34 3.0 UniRef50_Q02BY2 Cluster: Putative uncharacterized protein precur... 34 3.0 UniRef50_A1WC27 Cluster: Beta-lactamase domain protein; n=9; cel... 34 3.0 UniRef50_UPI0000EB2486 Cluster: Uncharacterized protein C9orf140... 33 3.9 UniRef50_Q39HP1 Cluster: Hydroxyacylglutathione hydrolase; n=55;... 33 3.9 UniRef50_Q1IPB4 Cluster: Beta-lactamase-like precursor; n=1; Aci... 33 3.9 UniRef50_A6GHH4 Cluster: Beta-lactamase-like protein; n=1; Plesi... 33 3.9 UniRef50_A5V998 Cluster: Hydroxyacylglutathione hydrolase; n=1; ... 33 3.9 UniRef50_A5P820 Cluster: Beta-lactamase-like protein; n=1; Eryth... 33 3.9 UniRef50_A3JY79 Cluster: Metallo-beta-lactamase; n=1; Sagittula ... 33 3.9 UniRef50_Q10PC8 Cluster: Hydroxyproline-rich glycoprotein family... 33 3.9 UniRef50_A3AFX3 Cluster: Putative uncharacterized protein; n=1; ... 33 3.9 UniRef50_Q4Q4V2 Cluster: Putative uncharacterized protein; n=3; ... 33 3.9 UniRef50_UPI00005A28D5 Cluster: PREDICTED: hypothetical protein ... 33 5.2 UniRef50_Q8Y6A5 Cluster: Lmo1790 protein; n=11; Listeria|Rep: Lm... 33 5.2 UniRef50_Q47TR0 Cluster: Putative hydrolase; n=1; Thermobifida f... 33 5.2 UniRef50_Q1GRV6 Cluster: Beta-lactamase-like protein; n=1; Sphin... 33 5.2 UniRef50_Q08X15 Cluster: Putative uncharacterized protein; n=1; ... 33 5.2 UniRef50_A5IMS0 Cluster: Beta-lactamase domain protein; n=2; The... 33 5.2 UniRef50_Q7QXR8 Cluster: GLP_399_8255_9553; n=1; Giardia lamblia... 33 5.2 UniRef50_Q4QCE8 Cluster: Metallo-beta-lactamase family-like prot... 33 5.2 UniRef50_A1CDF5 Cluster: NF-X1 finger transcription factor, puta... 33 5.2 UniRef50_Q8ZT88 Cluster: Beta-lactamase-like protein; n=4; Pyrob... 33 5.2 UniRef50_Q18JI1 Cluster: Metallo-beta-lactamase family protein /... 33 5.2 UniRef50_Q5SIE5 Cluster: Metallo-beta-lactamase family protein; ... 33 6.9 UniRef50_Q1LMU9 Cluster: Beta-lactamase-like protein; n=3; Cupri... 33 6.9 UniRef50_Q09CU6 Cluster: Metallo-beta-lactamase family protein; ... 33 6.9 UniRef50_A6CMS1 Cluster: Metallo-beta-lactamase family protein; ... 33 6.9 UniRef50_Q5CWB4 Cluster: VPS13 like protein involved in vacuolar... 33 6.9 UniRef50_Q29LU5 Cluster: GA13545-PA; n=1; Drosophila pseudoobscu... 33 6.9 UniRef50_A5K1D4 Cluster: Putative uncharacterized protein; n=1; ... 33 6.9 UniRef50_A2DNB4 Cluster: Putative uncharacterized protein; n=5; ... 33 6.9 UniRef50_A1CUD3 Cluster: Metallo-beta-lactamase domain protein, ... 33 6.9 UniRef50_Q89GW5 Cluster: Blr6230 protein; n=4; Bradyrhizobium|Re... 32 9.1 UniRef50_Q72KR0 Cluster: Metallo-beta-lactamase protein; n=2; Th... 32 9.1 UniRef50_Q47SL7 Cluster: Similar to Zn-dependent hydrolases incl... 32 9.1 UniRef50_Q3A9D5 Cluster: Metallo-beta-lactamase family protein; ... 32 9.1 UniRef50_Q2RLT5 Cluster: Beta-lactamase-like; n=1; Moorella ther... 32 9.1 UniRef50_A5VFI5 Cluster: Beta-lactamase domain protein; n=2; Sph... 32 9.1 UniRef50_A1SDT5 Cluster: Beta-lactamase domain protein; n=2; Act... 32 9.1 >UniRef50_Q7PPW0 Cluster: ENSANGP00000000940; n=6; cellular organisms|Rep: ENSANGP00000000940 - Anopheles gambiae str. PEST Length = 248 Score = 233 bits (571), Expect = 2e-60 Identities = 103/151 (68%), Positives = 126/151 (83%) Frame = +2 Query: 134 GKLKSLVPGTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQS 313 G LK L+PGT SVI + SGA+AD HL+D + V+FG HEL A +TPGHTNGC+T++ EQ Sbjct: 81 GFLKQLLPGTVSVISQSSGAKADKHLVDNETVQFGRHELRAMSTPGHTNGCMTFLVEEQG 140 Query: 314 LAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEE 493 +AFTGDTLLIRGCGRTDFQEG+S +LY+SVH RIFTLP+ + L+PAHDY+G T+VAEE Sbjct: 141 IAFTGDTLLIRGCGRTDFQEGDSRSLYRSVHERIFTLPENFRLFPAHDYKGNMETTVAEE 200 Query: 494 KKYNPRLTKSLAEFVEIMDNLNLPYPKMINK 586 K+YNPRLTK + FVE+M+NLNLPYPKMI K Sbjct: 201 KRYNPRLTKDVEAFVELMNNLNLPYPKMIGK 231 >UniRef50_A1Z8L2 Cluster: CG30022-PA; n=7; Diptera|Rep: CG30022-PA - Drosophila melanogaster (Fruit fly) Length = 279 Score = 207 bits (505), Expect = 2e-52 Identities = 94/149 (63%), Positives = 117/149 (78%) Frame = +2 Query: 134 GKLKSLVPGTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQS 313 G L+ L G +SVI SGA+AD HL +GD + FG+H + A ATPGHTNGC+TY+ +Q Sbjct: 114 GWLRKLT-GCQSVIAAASGAKADRHLNEGDRIDFGTHVIDALATPGHTNGCMTYVIKDQG 172 Query: 314 LAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEE 493 FTGDTLLIRGCGRTDFQEG LY++VH++IFTLP+ + +YPAHDY+GQ +SV EE Sbjct: 173 CVFTGDTLLIRGCGRTDFQEGCPRNLYENVHSKIFTLPENFRIYPAHDYKGQMESSVWEE 232 Query: 494 KKYNPRLTKSLAEFVEIMDNLNLPYPKMI 580 K+YNPRLTK + EFV+IM+NLNLPYPK I Sbjct: 233 KRYNPRLTKDIEEFVKIMENLNLPYPKKI 261 >UniRef50_O95571 Cluster: ETHE1 protein, mitochondrial precursor; n=36; cellular organisms|Rep: ETHE1 protein, mitochondrial precursor - Homo sapiens (Human) Length = 254 Score = 200 bits (489), Expect = 2e-50 Identities = 91/152 (59%), Positives = 118/152 (77%) Frame = +2 Query: 134 GKLKSLVPGTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQS 313 G L+SL+PG +SVI + SGAQAD+H+ DGD +RFG L A+PGHT GC+T++ ++ S Sbjct: 89 GLLRSLLPGCQSVISRLSGAQADLHIEDGDSIRFGRFALETRASPGHTPGCVTFVLNDHS 148 Query: 314 LAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEE 493 +AFTGD LLIRGCGRTDFQ+G ++TLY SVH +IFTLP + ++YPAHDY G T ++V EE Sbjct: 149 MAFTGDALLIRGCGRTDFQQGCAKTLYHSVHEKIFTLPGDCLIYPAHDYHGFTVSTVEEE 208 Query: 494 KKYNPRLTKSLAEFVEIMDNLNLPYPKMINKA 589 + NPRLT S EFV+IM NLNLP P+ I+ A Sbjct: 209 RTLNPRLTLSCEEFVKIMGNLNLPKPQQIDFA 240 >UniRef50_Q39B63 Cluster: Beta-lactamase-like; n=16; Proteobacteria|Rep: Beta-lactamase-like - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 356 Score = 162 bits (393), Expect = 7e-39 Identities = 79/147 (53%), Positives = 102/147 (69%), Gaps = 3/147 (2%) Frame = +2 Query: 158 GTKSVIGKDSGAQ-ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDT 334 G+ I SGAQ AD +L DGD FG+ L ATPGHT+GC++ + ++S+AFTGD Sbjct: 74 GSTIAISAASGAQGADRYLNDGDRCAFGARYLTVRATPGHTSGCISLVLDDESMAFTGDC 133 Query: 335 LLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 LLIRG GRTDFQ+G+ LY++VH R+FTLP +LYPAHDYRG T TSV EE+++NPRL Sbjct: 134 LLIRGTGRTDFQQGDPRALYRAVHGRLFTLPAACLLYPAHDYRGLTVTSVGEERRFNPRL 193 Query: 515 TKSLAE--FVEIMDNLNLPYPKMINKA 589 L+E F M NL L +P+ I+ A Sbjct: 194 GGDLSEDDFAGYMRNLGLAHPRQIDVA 220 >UniRef50_A3M5E1 Cluster: Beta-lactamase-like protein; n=1; Acinetobacter baumannii ATCC 17978|Rep: Beta-lactamase-like protein - Acinetobacter baumannii (strain ATCC 17978 / NCDC KC 755) Length = 231 Score = 151 bits (367), Expect = 9e-36 Identities = 70/145 (48%), Positives = 103/145 (71%), Gaps = 3/145 (2%) Frame = +2 Query: 164 KSVIGKDSGAQA-DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLL 340 KSV+ ++S DI + DG +++ G+ + A TPGHTN C +Y+ ++ FTGD LL Sbjct: 76 KSVLHRNSEVSCGDILITDGCMLKVGNLSIEARYTPGHTNACTSYLVG--NMIFTGDALL 133 Query: 341 IRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL-- 514 I GCGRTDFQ+GN+ TLY S+H ++F+LPD +LYP HDY+G+ ++++ E+ N RL Sbjct: 134 IDGCGRTDFQQGNAGTLYDSIHKQLFSLPDNTILYPGHDYKGRLSSTIGYERLNNSRLGQ 193 Query: 515 TKSLAEFVEIMDNLNLPYPKMINKA 589 +S +F+E+M+NLNLPYPK I+KA Sbjct: 194 NRSREDFIELMNNLNLPYPKQIDKA 218 >UniRef50_Q3J9M7 Cluster: Metallo-beta-lactamase family protein; n=6; Proteobacteria|Rep: Metallo-beta-lactamase family protein - Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) Length = 361 Score = 149 bits (361), Expect = 5e-35 Identities = 76/147 (51%), Positives = 102/147 (69%), Gaps = 3/147 (2%) Frame = +2 Query: 158 GTKSVIGKDSGAQ-ADIHLLDGDLVRFGS-HELLAAATPGHTNGCLTYICHEQSLAFTGD 331 G K+ IG+ GAQ AD L DG ++ FG E+ ATPGHT G ++Y+ ++ FTGD Sbjct: 74 GAKTGIGQACGAQYADYQLKDGVVLAFGQGEEIKVLATPGHTPGSISYLWRDR--VFTGD 131 Query: 332 TLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPR 511 LLI GCGRTDFQ G+ TLY SV ++FTLP E ++YP HDY G+ +SV +E+ N R Sbjct: 132 ALLINGCGRTDFQGGDPGTLYDSVTQKLFTLPGETIVYPGHDYNGRWVSSVEQERTGNGR 191 Query: 512 LT-KSLAEFVEIMDNLNLPYPKMINKA 589 L K+ AEF+EIM+NLNLP P++I++A Sbjct: 192 LAGKTRAEFIEIMNNLNLPKPRLIDEA 218 >UniRef50_A3Z5B4 Cluster: Beta-lactamase-like; n=2; Synechococcus|Rep: Beta-lactamase-like - Synechococcus sp. RS9917 Length = 370 Score = 147 bits (356), Expect = 2e-34 Identities = 75/148 (50%), Positives = 99/148 (66%), Gaps = 5/148 (3%) Frame = +2 Query: 161 TKSVIGKDSGAQADI---HLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGD 331 T + IG + A+A+ L GD V FG+ L ATPGHT+GCLT++ + S AFTGD Sbjct: 88 TGAAIGLAAAARAENVTQPLQHGDRVGFGARALEVRATPGHTDGCLTFVLDDASAAFTGD 147 Query: 332 TLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPR 511 LLIRGCGR+DFQ+GN+ TLY+S+ +I +LPD+ +LYP HDY G+ TSVAEE+ N R Sbjct: 148 ALLIRGCGRSDFQQGNAHTLYRSITEQILSLPDQCLLYPGHDYSGRQVTSVAEERALNAR 207 Query: 512 LTKSLAE--FVEIMDNLNLPYPKMINKA 589 L E FV M++L LP+P I +A Sbjct: 208 LGGGADERDFVIHMESLKLPHPHRIAQA 235 >UniRef50_Q4FRC2 Cluster: Possible Beta-lactamase-like superfamily protein; n=11; Bacteria|Rep: Possible Beta-lactamase-like superfamily protein - Psychrobacter arcticum Length = 249 Score = 138 bits (335), Expect = 7e-32 Identities = 69/135 (51%), Positives = 92/135 (68%), Gaps = 2/135 (1%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D+ L +G ++ L TPGHT+G Y+ +EQ FTGD LLI GCGRTDFQ G+ Sbjct: 89 DVGLEEGTPLQVAGITLHPLHTPGHTDGHFAYLFNEQ--VFTGDALLIDGCGRTDFQNGD 146 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTK--SLAEFVEIMDN 553 ++ LYKSV ++F+LPD+ ++YPAHDY+ +S+A+EKK NPRL + +L EF IM N Sbjct: 147 ADALYKSVRQKLFSLPDDTLVYPAHDYKECFVSSIAQEKKRNPRLGEDITLEEFKVIMSN 206 Query: 554 LNLPYPKMINKAGAG 598 LNLPYPK I+ A G Sbjct: 207 LNLPYPKFIDYAVPG 221 >UniRef50_Q89VN8 Cluster: Bll1007 protein; n=15; Proteobacteria|Rep: Bll1007 protein - Bradyrhizobium japonicum Length = 345 Score = 137 bits (331), Expect = 2e-31 Identities = 67/143 (46%), Positives = 95/143 (66%), Gaps = 2/143 (1%) Frame = +2 Query: 167 SVIGKDSGAQA-DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI 343 +V+G + A + + DGD V L TPGHT+ +Y+ ++ FTGDTLLI Sbjct: 77 TVMGDQTKADVVAMRVADGDKVTIEGLSLDVMYTPGHTDDSYSYLMGDR--VFTGDTLLI 134 Query: 344 RGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL-TK 520 RG GRTDFQ G+S Y S+ NR+ LPDE +++PAHDY+G T +++ EEK+YNPRL + Sbjct: 135 RGTGRTDFQNGSSRAQYDSIFNRLLKLPDETMVFPAHDYKGDTVSTIGEEKRYNPRLQVR 194 Query: 521 SLAEFVEIMDNLNLPYPKMINKA 589 S+ E++E+M NL LP PKM++ A Sbjct: 195 SVDEYIELMANLKLPNPKMMDVA 217 >UniRef50_Q31H45 Cluster: Metallo-beta-lactamase superfamily protein; n=1; Thiomicrospira crunogena XCL-2|Rep: Metallo-beta-lactamase superfamily protein - Thiomicrospira crunogena (strain XCL-2) Length = 229 Score = 137 bits (331), Expect = 2e-31 Identities = 67/150 (44%), Positives = 101/150 (67%), Gaps = 3/150 (2%) Frame = +2 Query: 158 GTKSVIGKDSGAQ-ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDT 334 G + V+ K+SG++ ADI +DGD+ + G E+ TPGHTN +TY + FTGDT Sbjct: 74 GGQLVVHKNSGSECADILAVDGDVFKLGDQEIHVLHTPGHTNNDITY--QIEGAVFTGDT 131 Query: 335 LLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 L++R CGRTDFQ G+++ +Y S+ +F LP++ +++PAHDY+G + +++ EEK++N R Sbjct: 132 LMVRDCGRTDFQLGDNKAMYHSLTEILFKLPEDTMVFPAHDYKGFSQSTIGEEKQFNNRA 191 Query: 515 --TKSLAEFVEIMDNLNLPYPKMINKAGAG 598 KS +F IMD+LNLP PK I+ A G Sbjct: 192 GSNKSYEDFSTIMDSLNLPNPKRIDIAVPG 221 >UniRef50_A0Q7P5 Cluster: Zn-dependent hydrolase; n=15; Gammaproteobacteria|Rep: Zn-dependent hydrolase - Francisella tularensis subsp. novicida (strain U112) Length = 228 Score = 137 bits (331), Expect = 2e-31 Identities = 70/146 (47%), Positives = 98/146 (67%), Gaps = 2/146 (1%) Frame = +2 Query: 158 GTKSVIGKDSGAQ-ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDT 334 G VIG +S A+ A + DGD++ FG+++L A TPGHT+ +I +++ FTGDT Sbjct: 74 GCDIVIGGESKAECATKKVFDGDILEFGNYQLKALYTPGHTDDSYCFIT--ENMLFTGDT 131 Query: 335 LLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 LLIRG GRTDFQ G+S Y S+ N++ TLP ++YP HDY G T++SVAEE++ NPRL Sbjct: 132 LLIRGSGRTDFQNGDSYAAYDSIMNKLMTLPGSTIIYPGHDYNGITSSSVAEERQNNPRL 191 Query: 515 -TKSLAEFVEIMDNLNLPYPKMINKA 589 KS E+ ++M +L LP P I+ A Sbjct: 192 KVKSPDEYAKLMADLKLPPPNYIDIA 217 >UniRef50_A1AX88 Cluster: Beta-lactamase domain protein; n=1; Candidatus Ruthia magnifica str. Cm (Calyptogena magnifica)|Rep: Beta-lactamase domain protein - Ruthia magnifica subsp. Calyptogena magnifica Length = 236 Score = 136 bits (329), Expect = 4e-31 Identities = 66/133 (49%), Positives = 93/133 (69%), Gaps = 2/133 (1%) Frame = +2 Query: 197 ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376 ADI L D D + FG + L A ATPGHT+GC++Y+ + Q FTGDTLLIR CGR DFQ G Sbjct: 91 ADILLNDNDTLSFGDYTLSAMATPGHTDGCMSYVVNNQ--IFTGDTLLIRSCGRCDFQGG 148 Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSL--AEFVEIMD 550 ++E L+ S+ +IFTLPDE ++YPAHDY G+T +S+ EEK++N + ++ EF ++ Sbjct: 149 SAEKLFDSIQ-KIFTLPDETLVYPAHDYGGRTVSSIWEEKQFNEMIGSNVNKQEFTRRVN 207 Query: 551 NLNLPYPKMINKA 589 + L +PK I+ A Sbjct: 208 TMKLDFPKKIHVA 220 >UniRef50_Q2JKB1 Cluster: Metallo-beta-lactamase domain protein; n=14; Bacteria|Rep: Metallo-beta-lactamase domain protein - Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone B-Prime) Length = 238 Score = 130 bits (314), Expect = 2e-29 Identities = 70/160 (43%), Positives = 99/160 (61%), Gaps = 8/160 (5%) Frame = +2 Query: 134 GKLKSLVPGTKSVIGKDSGAQ-ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQ 310 GKL+ L G + V+ + AQ AD + G+ ++ GS + A AT GHT+ +TY + Sbjct: 67 GKLRELT-GCQGVVPVQAKAQCADRFIGHGETLQVGSVVIEAIATLGHTDSHMTYRVNGD 125 Query: 311 SLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAE 490 + TGD LLIRGCGRTDFQ G+ +Y V +FTLPDE ++YP HDYRG T +++ E Sbjct: 126 RV-LTGDALLIRGCGRTDFQSGDPGLMYDHVTQHLFTLPDETLVYPGHDYRGHTVSTIGE 184 Query: 491 EKKYNPRLT-------KSLAEFVEIMDNLNLPYPKMINKA 589 EK++NPR +S F+ +M++LNLP PK I +A Sbjct: 185 EKRWNPRFVDPETGNLRSRESFIALMNSLNLPQPKKIQEA 224 >UniRef50_Q121S4 Cluster: Beta-lactamase-like; n=1; Polaromonas sp. JS666|Rep: Beta-lactamase-like - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 346 Score = 103 bits (246), Expect = 4e-21 Identities = 55/146 (37%), Positives = 86/146 (58%), Gaps = 2/146 (1%) Frame = +2 Query: 158 GTKSVIGKDSGAQA-DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDT 334 G +V+ + S A D+ + DG+++ G L TPGHT + + ++ FTGDT Sbjct: 72 GAMTVMHRASPAPGVDLRVDDGEMIVLGKLRLQVLYTPGHTVDSMCLVADDR--VFTGDT 129 Query: 335 LLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 LLI G GRTD G+ E LY S+ R+ L ++YPAHDY+G++ +++ +E NPRL Sbjct: 130 LLIGGTGRTDLPTGDPEALYDSLFGRLLKLDPALLVYPAHDYKGRSHSTIGDEIATNPRL 189 Query: 515 TKS-LAEFVEIMDNLNLPYPKMINKA 589 ++ A FVE+M +L+L P + +A Sbjct: 190 QRTDRAAFVEMMKSLDLSMPTHLTEA 215 >UniRef50_A6PAH2 Cluster: Beta-lactamase domain protein; n=1; Shewanella sediminis HAW-EB3|Rep: Beta-lactamase domain protein - Shewanella sediminis HAW-EB3 Length = 354 Score = 91.5 bits (217), Expect = 1e-17 Identities = 49/131 (37%), Positives = 73/131 (55%), Gaps = 1/131 (0%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D+++ DG+++ G L TPGHT + + ++ FTGDTLL+ G GRTD G+ Sbjct: 90 DMYVDDGEIIIVGKLRLTIMHTPGHTADSICIVMKDR--VFTGDTLLLGGTGRTDLPSGD 147 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL-TKSLAEFVEIMDNL 556 E LY S+ N + L + +YPAH Y +T +S+ EE NPRL K EFV M + Sbjct: 148 PERLYDSLFNGLLKLSADLKVYPAHAYSERTHSSIGEELSNNPRLQKKDRDEFVAQMRAI 207 Query: 557 NLPYPKMINKA 589 +L P + ++ Sbjct: 208 DLKMPTQLTES 218 >UniRef50_Q1NKM3 Cluster: Beta-lactamase-like; n=3; Deltaproteobacteria|Rep: Beta-lactamase-like - delta proteobacterium MLMS-1 Length = 213 Score = 87.8 bits (208), Expect = 2e-16 Identities = 51/120 (42%), Positives = 67/120 (55%), Gaps = 2/120 (1%) Frame = +2 Query: 167 SVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNG--CLTYICHEQSLAFTGDTLL 340 S++G + D L DGD V G+ EL TPGHT G CL H FTGDTL Sbjct: 96 SMLGLPASPPPDRLLQDGDTVVLGTIELQVIHTPGHTPGGICLYTAPH----LFTGDTLF 151 Query: 341 IRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTK 520 + G GRTDF G++ TL S+ R+ LP E V++P H Y G +T + EE + NP L++ Sbjct: 152 VGGVGRTDFPGGDTATLVNSLQQRLLKLPPETVVWPGHGYGGARST-IGEEARDNPYLSE 210 >UniRef50_Q1FHG0 Cluster: Beta-lactamase-like; n=1; Clostridium phytofermentans ISDg|Rep: Beta-lactamase-like - Clostridium phytofermentans ISDg Length = 216 Score = 87.0 bits (206), Expect = 3e-16 Identities = 44/114 (38%), Positives = 61/114 (53%) Frame = +2 Query: 167 SVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIR 346 S+ GK L D + ++F E + TPGHT G + Y ++ + +GDTL Sbjct: 98 SIFGKSLTLAPVESLHDLEKIQFADIEFVVLHTPGHTKGSVCYYIPDEQILLSGDTLFFE 157 Query: 347 GCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 GRTDF GNSE L KS++ R+FTLP E +YP H +TS+ E + NP Sbjct: 158 SVGRTDFPTGNSEVLVKSINERLFTLPKEVKVYPGHG----CSTSIGYEMQNNP 207 >UniRef50_A5ZNH8 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 209 Score = 85.0 bits (201), Expect = 1e-15 Identities = 39/105 (37%), Positives = 59/105 (56%) Frame = +2 Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373 +AD++L D +V + TPGHT G Y ++ + F+GDT+ GRTDF E Sbjct: 107 KADVYLTDLQVVELAGFSVQMIETPGHTLGSCCYYLKDEGVLFSGDTVFCGSVGRTDFPE 166 Query: 374 GNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 G++ + S+H + LPD +YP HD T+T++ EK+YNP Sbjct: 167 GSTAAIVNSLHRLLEALPDNTEVYPGHD----TSTTIGYEKRYNP 207 >UniRef50_Q2LRW6 Cluster: Hydroxyacylglutathione hydrolase W; n=1; Syntrophus aciditrophicus SB|Rep: Hydroxyacylglutathione hydrolase W - Syntrophus aciditrophicus (strain SB) Length = 257 Score = 83.8 bits (198), Expect = 3e-15 Identities = 45/118 (38%), Positives = 67/118 (56%), Gaps = 3/118 (2%) Frame = +2 Query: 170 VIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNG--CLTYICHEQSLAFTGDTLLI 343 + G + AD+ + DGD + G L TPGH+ G CL YI + FTGDTL + Sbjct: 144 MFGAEDSPPADMTVKDGDTITVGKISLKVIHTPGHSPGGMCL-YI---KGFVFTGDTLFV 199 Query: 344 RGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATS-VAEEKKYNPRL 514 GRTD ++ +++S+ ++ TLPD+ + P H+Y G+T+TS + EK YNP L Sbjct: 200 ESVGRTDLNGSSASQMFRSIREKLLTLPDDTQVLPGHNY-GRTSTSTIGHEKIYNPFL 256 >UniRef50_A0LJ17 Cluster: Beta-lactamase domain protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Beta-lactamase domain protein - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 214 Score = 81.0 bits (191), Expect = 2e-14 Identities = 45/121 (37%), Positives = 64/121 (52%), Gaps = 1/121 (0%) Frame = +2 Query: 158 GTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNG-CLTYICHEQSLAFTGDT 334 G ++G AD+ + DGD + FG+ + TPGHT G C I FTGDT Sbjct: 93 GFARMMGFQPAPPADVRVEDGDELTFGNLTMKFINTPGHTPGSCCVLI---DGNLFTGDT 149 Query: 335 LLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 L + GRTD G+ L +S+ +I TLP + V++P HDY + ++V E K NP + Sbjct: 150 LFVGAVGRTDLPGGSFGELIQSLKTKIVTLPPDTVVWPGHDYGDRPFSTVKHEMKTNPYI 209 Query: 515 T 517 T Sbjct: 210 T 210 >UniRef50_A0RY05 Cluster: Zn-dependent hydrolase; n=2; Thermoprotei|Rep: Zn-dependent hydrolase - Cenarchaeum symbiosum Length = 203 Score = 81.0 bits (191), Expect = 2e-14 Identities = 43/131 (32%), Positives = 68/131 (51%), Gaps = 1/131 (0%) Frame = +2 Query: 158 GTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTL 337 G + + ++S + DI + DG +R GS L TPGH+ + + FTGDTL Sbjct: 73 GARIIQHEESELKHDITVRDGSEIRIGSTMLSVLHTPGHSRDSICLV--GDGKIFTGDTL 130 Query: 338 LIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLT 517 + CGR D G++ LY S+ ++ L D V+Y HDY +++ +EKK NP + Sbjct: 131 FVGSCGRVDLPGGSARDLYGSIFGVLYRLDDSLVVYCGHDYGTSPVSTLGDEKKSNPVMR 190 Query: 518 K-SLAEFVEIM 547 + +FV +M Sbjct: 191 RVGEEQFVAMM 201 >UniRef50_A5G5N2 Cluster: Beta-lactamase domain protein precursor; n=5; Desulfuromonadales|Rep: Beta-lactamase domain protein precursor - Geobacter uraniumreducens Rf4 Length = 251 Score = 80.2 bits (189), Expect = 3e-14 Identities = 42/110 (38%), Positives = 61/110 (55%), Gaps = 1/110 (0%) Frame = +2 Query: 182 DSGAQADIHLLDGDLVRFGSHELLAAATPGHT-NGCLTYICHEQSLAFTGDTLLIRGCGR 358 ++ + D L DG +V FGS +L TPGHT GC Y+ + TGDTL G GR Sbjct: 142 ENSPKPDGLLEDGMVVIFGSQQLKVLHTPGHTPGGCCLYL-ESEGKVITGDTLFADGVGR 200 Query: 359 TDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 TDF + E L + + N++FTLP+ ++YP H ++++ EK NP Sbjct: 201 TDFPGSSHEALIEGIRNKLFTLPEPTLVYPGHG----PSSNIGHEKSNNP 246 >UniRef50_Q6MNF6 Cluster: Metallo-beta-lactamase superfamily protein; n=3; Proteobacteria|Rep: Metallo-beta-lactamase superfamily protein - Bdellovibrio bacteriovorus Length = 286 Score = 79.8 bits (188), Expect = 5e-14 Identities = 51/143 (35%), Positives = 80/143 (55%), Gaps = 11/143 (7%) Frame = +2 Query: 185 SGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGR 358 SG+ DI L +G++++ GS ++ TPGHT C +Y+ + FTGD L + G GR Sbjct: 116 SGSDFDILLKEGEVLQAGSLKIKTLFTPGHTPACASYLIEDA--IFTGDALFMPDSGTGR 173 Query: 359 TDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYR--GQT---ATSVAEEKKYNPRLT-- 517 DF G++E LY SV +I++LP+ ++ HDY+ G+ T+V EEK N +L Sbjct: 174 CDFPAGSAENLYDSVTGKIYSLPENTRIFVGHDYQPNGRALMYQTTVNEEKNQNIQLKGH 233 Query: 518 KSLAEFVEIMD--NLNLPYPKMI 580 S +FV+ + L PK++ Sbjct: 234 TSKEDFVKFRQERDATLAAPKLL 256 >UniRef50_Q0SRP5 Cluster: Metallo-beta-lactamase family protein; n=8; Clostridium|Rep: Metallo-beta-lactamase family protein - Clostridium perfringens (strain SM101 / Type A) Length = 206 Score = 79.4 bits (187), Expect = 6e-14 Identities = 43/108 (39%), Positives = 67/108 (62%), Gaps = 1/108 (0%) Frame = +2 Query: 194 QADIHLLDGDLVRFG-SHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQ 370 +AD +L DGD ++F ++E+ TPGHT G L ++ + FTGDTL GR+DF+ Sbjct: 98 KADGYLKDGDTLKFSDNYEIKCLETPGHTPGGLCFLI--DNCLFTGDTLFRESIGRSDFE 155 Query: 371 EGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 GN TL KS+++++ L D+ V+YP H G ++T + E++ NP L Sbjct: 156 GGNHATLLKSINDKLVPLGDDIVVYPGH---GPSST-IKHERQRNPFL 199 >UniRef50_A1IE49 Cluster: Hydroxyacylglutathione hydrolase W; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Hydroxyacylglutathione hydrolase W - Candidatus Desulfococcus oleovorans Hxd3 Length = 220 Score = 79.4 bits (187), Expect = 6e-14 Identities = 39/113 (34%), Positives = 59/113 (52%) Frame = +2 Query: 170 VIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRG 349 ++G + D+ L G+ V G L TPGHT G + + F GDTL + Sbjct: 105 LLGGRPSPRPDVVLQHGEAVVLGQTTLTVLHTPGHTPGSICL--YMPGHLFAGDTLFVGS 162 Query: 350 CGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 GRTD G+ + L+ S+ R+F LPD+ ++P HDY + +++ EKK NP Sbjct: 163 AGRTDLSGGSIKDLHASIRTRLFPLPDDTRVWPGHDYGDRPVSTIGHEKKTNP 215 >UniRef50_Q1IQE8 Cluster: Beta-lactamase-like; n=2; Acidobacteria|Rep: Beta-lactamase-like - Acidobacteria bacterium (strain Ellin345) Length = 209 Score = 79.0 bits (186), Expect = 8e-14 Identities = 42/113 (37%), Positives = 59/113 (52%), Gaps = 1/113 (0%) Frame = +2 Query: 179 KDSG-AQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCG 355 KD G D L DGD V+FG+ E TPGHT G + + + GDTL G Sbjct: 99 KDPGKVVVDESLADGDSVKFGTIEGSVIHTPGHTQGSICLLLKSEKTLIAGDTLFQGSIG 158 Query: 356 RTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 RTD G+ E + KS+H ++ LP E ++ P H +T++ EE++ NP L Sbjct: 159 RTDLPGGSYEKIMKSIHGKLLVLPGETIVIPGHG----PSTTIEEERERNPFL 207 >UniRef50_A5EXZ6 Cluster: Metallo-beta-lactamase superfamily protein; n=1; Dichelobacter nodosus VCS1703A|Rep: Metallo-beta-lactamase superfamily protein - Dichelobacter nodosus (strain VCS1703A) Length = 235 Score = 79.0 bits (186), Expect = 8e-14 Identities = 46/118 (38%), Positives = 69/118 (58%), Gaps = 2/118 (1%) Frame = +2 Query: 209 LLDGDLVRFGSHELLAAATPGHTNG-CLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSE 385 L DGD + G+ + ATPGHT G C Y+ + +L TGDTL + GCGRTDF G+S Sbjct: 95 LQDGDEIFCGADVIQMIATPGHTAGSCCFYV--DNNL-ITGDTLFVYGCGRTDFPSGDSR 151 Query: 386 TLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLT-KSLAEFVEIMDNL 556 L++S+ ++ LP + HDY + ++++E+ YNP +T SL +FV + L Sbjct: 152 ALFESL-QKLKKLPPHTQILSGHDYGIEKNSTLSEQITYNPFMTICSLDDFVRFREEL 208 >UniRef50_Q64UQ6 Cluster: Putative metallo-beta-lactamase; n=5; Bacteroides|Rep: Putative metallo-beta-lactamase - Bacteroides fragilis Length = 212 Score = 78.6 bits (185), Expect = 1e-13 Identities = 38/101 (37%), Positives = 55/101 (54%) Frame = +2 Query: 206 HLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSE 385 +L DGD++ FG+ L A PGH+ G L Y C + F+GD L GR D GN + Sbjct: 113 YLHDGDIITFGNTTLEAIHVPGHSPGSLVYYCRADNCMFSGDVLFQGSIGRADLAGGNFD 172 Query: 386 TLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 L + + +R+F LP+E ++YP H T++ EK NP Sbjct: 173 ELKEHICSRLFVLPNETIVYPGHG----APTTIGIEKAENP 209 >UniRef50_Q1ZAD4 Cluster: Probable metallo-beta-lactamase superfamily protein; n=1; Photobacterium profundum 3TCK|Rep: Probable metallo-beta-lactamase superfamily protein - Photobacterium profundum 3TCK Length = 260 Score = 78.6 bits (185), Expect = 1e-13 Identities = 51/144 (35%), Positives = 80/144 (55%), Gaps = 11/144 (7%) Frame = +2 Query: 191 AQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGRTD 364 AQ D+ L +GD + G ++ +TPGHT LTY H F GDTL RG GR D Sbjct: 107 AQFDVLLDEGDELSLGGEKVSVLSTPGHTPADLTY--HIGDSIFVGDTLFAPKRGTGRAD 164 Query: 365 FQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQT-----ATSVAEEKKYNPRLTKSLA 529 F G+++ LY+S+ +R+F LP++ +Y HDY + +S++ +K N + S+ Sbjct: 165 FPGGSAKDLYRSI-SRLFELPEDTDVYLCHDYPSENEEPELCSSLSTQKSDNVMINTSVT 223 Query: 530 E--FVEIMD--NLNLPYPKMINKA 589 E ++EI + NL PK+++ A Sbjct: 224 EKQYIEIRTKRDSNLATPKLLDVA 247 >UniRef50_Q892B0 Cluster: Hydroxyacylglutathione hydrolase; n=3; Clostridium|Rep: Hydroxyacylglutathione hydrolase - Clostridium tetani Length = 201 Score = 78.2 bits (184), Expect = 1e-13 Identities = 42/124 (33%), Positives = 67/124 (54%) Frame = +2 Query: 143 KSLVPGTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAF 322 +S++ G + ADI + +GD + G E+ TPGH+ G + ++ +++ F Sbjct: 84 ESILKGMDLFGNSQTCGAADIKIKEGDTFKIGDKEIKCIETPGHSLGGMCFLI--ENIIF 141 Query: 323 TGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKY 502 TGDTL GRTDF GN E L K++ +I T+P++ ++ P H T+V +EK Sbjct: 142 TGDTLFEGSIGRTDFYGGNFEILIKNIKEKILTIPEDTLVLPGHGME----TTVGKEKIS 197 Query: 503 NPRL 514 NP L Sbjct: 198 NPFL 201 >UniRef50_Q74E41 Cluster: Metallo-beta-lactamase family protein; n=4; Desulfuromonadales|Rep: Metallo-beta-lactamase family protein - Geobacter sulfurreducens Length = 209 Score = 78.2 bits (184), Expect = 1e-13 Identities = 42/106 (39%), Positives = 54/106 (50%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D L DG + G+ L TPGHT G + + TGDTL GRTDF + Sbjct: 107 DSLLEDGMTLSVGTLSLRVLHTPGHTPGGCCLLLEGEGKVLTGDTLFEESVGRTDFPGSS 166 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLT 517 E L S+ ++ TLPDE +YP H ATS+ E++YNP LT Sbjct: 167 HEALITSIREKLLTLPDETEVYPGHG----PATSIGRERRYNPYLT 208 >UniRef50_A6G5S2 Cluster: Metallo-beta-lactamase family protein; n=1; Plesiocystis pacifica SIR-1|Rep: Metallo-beta-lactamase family protein - Plesiocystis pacifica SIR-1 Length = 234 Score = 78.2 bits (184), Expect = 1e-13 Identities = 42/109 (38%), Positives = 62/109 (56%), Gaps = 2/109 (1%) Frame = +2 Query: 218 GDLVRFGSH-ELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394 GD VR G E+ TPGHT G +Y + + TGDTL + GCGR DF G+ E ++ Sbjct: 104 GDTVRVGEQLEITMMHTPGHTPGSCSYRLRDSIV--TGDTLFVNGCGRCDFVGGDPELMF 161 Query: 395 KSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLT-KSLAEFV 538 +++ + LP + V+YP H Y + +V E+ + NP L ++AEFV Sbjct: 162 ETLEALMSKLPKDTVMYPGHHYGPTPSATVDEQLRDNPYLKHTTVAEFV 210 >UniRef50_A6DU41 Cluster: Metallo-beta-lactamase family protein; n=1; Lentisphaera araneosa HTCC2155|Rep: Metallo-beta-lactamase family protein - Lentisphaera araneosa HTCC2155 Length = 222 Score = 78.2 bits (184), Expect = 1e-13 Identities = 49/134 (36%), Positives = 75/134 (55%), Gaps = 6/134 (4%) Frame = +2 Query: 185 SGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHE-QSLAFTGDTLLIRGCGRT 361 +G A +H GD ++ GS EL TPGHT G +C+E + FTGDT+ + GCGR Sbjct: 90 AGRNAKLHS-GGDFIKLGSIELKIHHTPGHTPGS---VCYELDNHLFTGDTVFVYGCGRC 145 Query: 362 DFQEGNSETLYKSVHNRIFTLPD-EYVLYPAHDYRGQTATSVAEEKKYNPRLT-KSLAEF 535 + + G+ E +Y ++ N+I T D + P HDY +++AE+ + NP K+L EF Sbjct: 146 NLRGGDPEAMYHTL-NKIGTNFDPSMTVLPGHDYASCATSTIAEQLQGNPFFNIKTLHEF 204 Query: 536 VEI---MDNLNLPY 568 V+ N ++PY Sbjct: 205 VDYRMHKHNRSIPY 218 >UniRef50_Q8RAL6 Cluster: Zn-dependent hydrolases, including glyoxylases; n=2; Thermoanaerobacter|Rep: Zn-dependent hydrolases, including glyoxylases - Thermoanaerobacter tengcongensis Length = 214 Score = 77.8 bits (183), Expect = 2e-13 Identities = 44/103 (42%), Positives = 60/103 (58%) Frame = +2 Query: 197 ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376 ADI L D D++ FG++ + +TPGHT G + + + + FTGDTL GR DF G Sbjct: 111 ADIILKDKDVLGFGNYYVEVISTPGHTKGSVCFKIGD--VYFTGDTLFRGSIGRHDFPGG 168 Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505 N ETL S+ R+ TL DE V+YP H G +T + EK+ N Sbjct: 169 NFETLMASIKERLLTLKDETVIYPGH---GDFST-IGREKRLN 207 >UniRef50_A6L4P4 Cluster: Putative metallo-beta-lactamase; n=2; Bacteroidales|Rep: Putative metallo-beta-lactamase - Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154) Length = 212 Score = 77.8 bits (183), Expect = 2e-13 Identities = 37/101 (36%), Positives = 55/101 (54%) Frame = +2 Query: 206 HLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSE 385 ++ DGD++ FG+ +L A PGH+ G + + C E F+GD L GR D GN + Sbjct: 113 YIFDGDIITFGNTQLEAIHVPGHSPGSIVFYCKEAHCIFSGDVLFQGSIGRADLTGGNFD 172 Query: 386 TLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 L + + +R+F LP + V+YP H T+V EK NP Sbjct: 173 ELREHICSRLFVLPPDTVVYPGHG----DPTTVGAEKANNP 209 >UniRef50_Q1PVC6 Cluster: Similar to hydroxyacylglutathione hydrolase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Similar to hydroxyacylglutathione hydrolase - Candidatus Kuenenia stuttgartiensis Length = 210 Score = 77.4 bits (182), Expect = 2e-13 Identities = 38/105 (36%), Positives = 59/105 (56%) Frame = +2 Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373 + D +L+D + + G + TPGH+ GC+ ++ + + F GDTL GRTD Sbjct: 110 KVDRYLIDNEELPLGDEVIRIIHTPGHSPGCVCFLFN--NAIFAGDTLFAGSVGRTDLYG 167 Query: 374 GNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 G+ +TL SV R+FTL D ++YP H T++ +EKK+NP Sbjct: 168 GSHDTLINSVKTRLFTLEDHVLVYPGHG----PVTTIGKEKKHNP 208 >UniRef50_A3SZ22 Cluster: Beta-lactamase-like; n=6; Proteobacteria|Rep: Beta-lactamase-like - Sulfitobacter sp. NAS-14.1 Length = 306 Score = 77.4 bits (182), Expect = 2e-13 Identities = 53/142 (37%), Positives = 74/142 (52%), Gaps = 11/142 (7%) Frame = +2 Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGRT 361 G+Q D DGD R G E A TPGHT C+ ++ + AFTGDTL + G R Sbjct: 138 GSQFDALFKDGDRYRVGGMECFAIYTPGHTPACMVHVM--GNAAFTGDTLFMPDGGSARA 195 Query: 362 DFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY--RG---QTATSVAEEKKYNPRL--TK 520 DF G++ LY S+ ++ +LPD+ L+ HDY G Q T+V EEK +N + K Sbjct: 196 DFPGGDAGELYDSI-QKVLSLPDDMRLFMCHDYGPNGRDIQWETTVGEEKAHNIHVGGGK 254 Query: 521 SLAEFVEIMD--NLNLPYPKMI 580 + EF+ + L PK+I Sbjct: 255 TREEFIAFRTERDAQLSMPKLI 276 >UniRef50_A0LFG7 Cluster: Beta-lactamase domain protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Beta-lactamase domain protein - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 215 Score = 76.6 bits (180), Expect = 4e-13 Identities = 41/104 (39%), Positives = 56/104 (53%) Frame = +2 Query: 197 ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376 AD L +GD++ FG L TPGHT G ++ E F GDT+ GRTDF G Sbjct: 113 ADRTLEEGDVLDFGPIRLSVIETPGHTPGHVSVYFPEAKSIFVGDTIFAGSIGRTDFPGG 172 Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 + + L +SV +IFTLP + ++YP H T+V E + NP Sbjct: 173 SHDRLIRSVKEKIFTLPGDTLVYPGHG----PGTTVEREMRTNP 212 >UniRef50_A1VR45 Cluster: Beta-lactamase domain protein; n=1; Polaromonas naphthalenivorans CJ2|Rep: Beta-lactamase domain protein - Polaromonas naphthalenivorans (strain CJ2) Length = 215 Score = 75.4 bits (177), Expect = 1e-12 Identities = 40/99 (40%), Positives = 58/99 (58%), Gaps = 1/99 (1%) Frame = +2 Query: 215 DGDLVRFGSHELLAA-ATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETL 391 DGDL+ FG HELL ATPGHT GCL++ ++ F G L + C E L Sbjct: 91 DGDLLPFG-HELLRVLATPGHTAGCLSFAWRDR--LFCGGLLAVDACPHQPIP-AQPEAL 146 Query: 392 YKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 + SV R+FTLPDE +L+ H R + ++V E+++++P Sbjct: 147 WDSVTQRVFTLPDETLLFAGHGRRARAVSTVLEQRRWHP 185 >UniRef50_A6L981 Cluster: Metallo-beta-lactamase family protein; n=1; Parabacteroides distasonis ATCC 8503|Rep: Metallo-beta-lactamase family protein - Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC11152) Length = 212 Score = 74.9 bits (176), Expect = 1e-12 Identities = 34/103 (33%), Positives = 57/103 (55%) Frame = +2 Query: 206 HLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSE 385 +L++G++++FG EL + PGH+ G + + + GD+L GRTD GN + Sbjct: 114 YLVNGEIIKFGKSELAVLSVPGHSPGGVAFYNKKNGFVIVGDSLFAGSIGRTDLWGGNQD 173 Query: 386 TLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 L ++ +++ +LPDE V+YP H T + +EK NP L Sbjct: 174 ILLAAIKDKLLSLPDETVVYPGHG----PETRIIDEKLNNPYL 212 >UniRef50_Q7MV11 Cluster: Metallo-beta-lactamase family protein; n=1; Porphyromonas gingivalis|Rep: Metallo-beta-lactamase family protein - Porphyromonas gingivalis (Bacteroides gingivalis) Length = 214 Score = 73.7 bits (173), Expect = 3e-12 Identities = 38/103 (36%), Positives = 55/103 (53%) Frame = +2 Query: 206 HLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSE 385 ++ GD+++ G + PGH+ G L + C + FTGD L GRTD G+ E Sbjct: 115 YIAPGDVLQLGESIIKVLFVPGHSPGHLAFYCPQAQAVFTGDALFAGDMGRTDLWGGSYE 174 Query: 386 TLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 L KS+ + LPD+ V+YP H G T+T +A E+ NP L Sbjct: 175 LLKKSIRTELLPLPDDTVVYPGH---GPTST-IAYERTNNPFL 213 >UniRef50_A4AWZ7 Cluster: Putative uncharacterized protein; n=2; Proteobacteria|Rep: Putative uncharacterized protein - Alteromonas macleodii 'Deep ecotype' Length = 284 Score = 73.3 bits (172), Expect = 4e-12 Identities = 46/142 (32%), Positives = 73/142 (51%), Gaps = 11/142 (7%) Frame = +2 Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGRT 361 G+Q D+ +GD G +E+ TPGHT C +++ F GDT+ G R Sbjct: 115 GSQFDVLFEEGDTFNIGEYEVTVWHTPGHTPACASFLV--DGKIFVGDTMFAPNLGTARC 172 Query: 362 DFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQ-----TATSVAEEKKYNPRLTK-- 520 DF G++E LY ++ R FTLPD+ +Y HDY + + S+ E K+ N ++ Sbjct: 173 DFPGGSAEQLYNTI-QRFFTLPDDTTVYLGHDYPKEGTAPLSTVSIKEAKETNKQIRPEV 231 Query: 521 SLAEFVEIMD--NLNLPYPKMI 580 +L E+VE + + L PK++ Sbjct: 232 TLQEYVEKREARDATLAVPKLL 253 >UniRef50_Q57544 Cluster: Uncharacterized protein HI1663; n=20; Pasteurellaceae|Rep: Uncharacterized protein HI1663 - Haemophilus influenzae Length = 212 Score = 73.3 bits (172), Expect = 4e-12 Identities = 35/100 (35%), Positives = 56/100 (56%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394 +G++++ PGHT G + +I HE+ +AFTGD L G GRTDF G+ ETL Sbjct: 113 EGEILKLDGFNFEILHLPGHTPGHIGFIEHEKKVAFTGDVLFQGGIGRTDFPRGDYETLI 172 Query: 395 KSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 S+ ++ L D+ ++ H + T++ +EK+ NP L Sbjct: 173 SSIRTKLLPLNDDIIIIAGHG----SYTTIGQEKRSNPFL 208 >UniRef50_Q314Q9 Cluster: Metallo-beta-lactamase family protein; n=3; Desulfovibrio|Rep: Metallo-beta-lactamase family protein - Desulfovibrio desulfuricans (strain G20) Length = 208 Score = 72.9 bits (171), Expect = 5e-12 Identities = 38/86 (44%), Positives = 47/86 (54%) Frame = +2 Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442 TPGHT G ++ + F GD L R GRTDF G+S TL SV IF+LPD V+ Sbjct: 124 TPGHTPGSFSFYFPQAEAVFVGDLLFHRSVGRTDFPGGDSATLLNSVKKAIFSLPDTTVV 183 Query: 443 YPAHDYRGQTATSVAEEKKYNPRLTK 520 YP H T+V +EK NP T+ Sbjct: 184 YPGHGIE----TTVGDEKLNNPFFTE 205 >UniRef50_Q08R44 Cluster: Myofibrillogenesis regulator 1; n=3; Cystobacterineae|Rep: Myofibrillogenesis regulator 1 - Stigmatella aurantiaca DW4/3-1 Length = 220 Score = 72.9 bits (171), Expect = 5e-12 Identities = 37/108 (34%), Positives = 57/108 (52%), Gaps = 1/108 (0%) Frame = +2 Query: 218 GDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYK 397 G+ + G LA TPGHT G + + ++ GDT+ I GCGR D + GN E +Y+ Sbjct: 107 GEALTVGPRTFLALHTPGHTPGSHCLLAGDALVS--GDTVFINGCGRCDMRGGNPEDMYR 164 Query: 398 SVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLT-KSLAEFV 538 S+ + +PDE L+P HDY ++ + ++ NP +A FV Sbjct: 165 SLSQVLLRVPDETRLWPGHDYAEVPVAAMGQVRQANPYFAFPDVASFV 212 >UniRef50_A6EK80 Cluster: Metallo-beta-lactamase family protein; n=1; Pedobacter sp. BAL39|Rep: Metallo-beta-lactamase family protein - Pedobacter sp. BAL39 Length = 220 Score = 72.9 bits (171), Expect = 5e-12 Identities = 41/123 (33%), Positives = 61/123 (49%), Gaps = 2/123 (1%) Frame = +2 Query: 152 VPGTKSVIGK--DSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFT 325 +PG +G + + ++ L + V FG L PGH+ L + E Sbjct: 101 IPGYAPQMGLSYELSPEPEVFLPEQGTVEFGKSALELIFVPGHSPAHLCFHAREDGFLIG 160 Query: 326 GDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505 GD L R GRTD GN + L S+ N +F LPD+ V+YP H GQ +T++ E+++N Sbjct: 161 GDALFYRSIGRTDLPGGNHDQLISSIRNNLFILPDDCVVYPGH---GQ-STTIGFEREHN 216 Query: 506 PRL 514 P L Sbjct: 217 PFL 219 >UniRef50_A4C5I4 Cluster: Beta-lactamase-like protein; n=1; Pseudoalteromonas tunicata D2|Rep: Beta-lactamase-like protein - Pseudoalteromonas tunicata D2 Length = 283 Score = 72.9 bits (171), Expect = 5e-12 Identities = 52/140 (37%), Positives = 71/140 (50%), Gaps = 12/140 (8%) Frame = +2 Query: 206 HLL-DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGRTDFQEG 376 HL DG+ G + ATPGHT+ + Y+ F GDT+ + G R DF G Sbjct: 120 HLFKDGETFPLGQFTVTVLATPGHTSDSVCYVVDGN--VFVGDTVFMPDSGTARCDFPGG 177 Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQ-----TATSVAEEKKYNPRLTK--SLAEF 535 ++ LY S+ +RIF L DE LY HDY+ Q T+V E+KKYN L S +F Sbjct: 178 DASELYHSI-SRIFDLGDEITLYMCHDYQPQGRELYWKTTVGEQKKYNVHLKNHTSQHDF 236 Query: 536 VEI--MDNLNLPYPKMINKA 589 V+I + L PK++ A Sbjct: 237 VKIRTQRDATLAVPKLLYPA 256 >UniRef50_Q191B3 Cluster: Beta-lactamase-like; n=3; Firmicutes|Rep: Beta-lactamase-like - Desulfitobacterium hafniense (strain DCB-2) Length = 205 Score = 72.5 bits (170), Expect = 7e-12 Identities = 41/106 (38%), Positives = 59/106 (55%) Frame = +2 Query: 197 ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376 AD L DG +++ G+ L ATPGHT G + ++ E L+ GDTL GRTDF G Sbjct: 105 ADFLLEDGQILQVGNLNLTVIATPGHTLGGVCFLTSEGLLS--GDTLFDGSIGRTDFPGG 162 Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 + + L KSV ++ LP++ +YP H T++ EK+ NP L Sbjct: 163 SYDELIKSVVKKLLVLPEDTKVYPGHG----PETTIGREKRENPFL 204 >UniRef50_A3IFE3 Cluster: YqgX; n=1; Bacillus sp. B14905|Rep: YqgX - Bacillus sp. B14905 Length = 214 Score = 72.5 bits (170), Expect = 7e-12 Identities = 33/87 (37%), Positives = 52/87 (59%) Frame = +2 Query: 254 AAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDE 433 A TPGH+ G ++Y+ A GDTL +G GRTD G+++ L S+H+++ TLP++ Sbjct: 129 AVFTPGHSPGSISYVFENDGFAIVGDTLFEQGVGRTDLIGGSTKILLASIHDKLLTLPED 188 Query: 434 YVLYPAHDYRGQTATSVAEEKKYNPRL 514 ++YP H T+V+ E + NP L Sbjct: 189 TIIYPGHG----NYTTVSAEMETNPFL 211 >UniRef50_Q97GU3 Cluster: Predicted Zn-dependent hydrolase of metallo-beta-lactamase superfamily; n=1; Clostridium acetobutylicum|Rep: Predicted Zn-dependent hydrolase of metallo-beta-lactamase superfamily - Clostridium acetobutylicum Length = 199 Score = 72.1 bits (169), Expect = 9e-12 Identities = 39/109 (35%), Positives = 60/109 (55%) Frame = +2 Query: 182 DSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRT 361 D A ++ DGD ++FG ++ TPGHT G + Y+ + F+GDTL GRT Sbjct: 95 DKSENATKYVDDGDELQFGELKIKCIKTPGHTPGGMCYLV--DNYLFSGDTLFNSSIGRT 152 Query: 362 DFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 DF G+ TL S+ +++ L + V+YP H G+ T++ EK +NP Sbjct: 153 DFPGGDFSTLINSIKSKLMKLDENIVVYPGH---GE-GTTIGYEKIHNP 197 >UniRef50_A3ZW37 Cluster: Putative uncharacterized protein; n=1; Blastopirellula marina DSM 3645|Rep: Putative uncharacterized protein - Blastopirellula marina DSM 3645 Length = 107 Score = 72.1 bits (169), Expect = 9e-12 Identities = 33/102 (32%), Positives = 57/102 (55%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394 +G ++ +L PGH++G + ++ H+ + GD L GRTDF +G+ L Sbjct: 4 EGAVLDLAGIQLEVRDAPGHSSGHVVFVIHDAQVVLGGDVLFAGSIGRTDFFDGDFGALR 63 Query: 395 KSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTK 520 ++H+++FTLP E+++YP H T++AEE NP + K Sbjct: 64 DAIHDKLFTLPGEFIVYPGHG----PETTIAEEIAENPFVGK 101 >UniRef50_A4J2H1 Cluster: Beta-lactamase domain protein; n=2; Bacteria|Rep: Beta-lactamase domain protein - Desulfotomaculum reducens MI-1 Length = 205 Score = 71.7 bits (168), Expect = 1e-11 Identities = 38/104 (36%), Positives = 59/104 (56%) Frame = +2 Query: 197 ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376 AD L+DGD ++ G+ L TPGHT G + + F+GDTL + GR+DF G Sbjct: 106 ADRLLVDGDTIQIGNITLEVLHTPGHTPGGICLKAGKD--LFSGDTLFAQSIGRSDFPGG 163 Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 + TL S+ +++ L DE +YP H A+++ +EK++NP Sbjct: 164 SHSTLIGSIKSKLLVLSDETKVYPGHG----PASTIGQEKRHNP 203 >UniRef50_A7C2X6 Cluster: Metallo-beta-lactamase family protein; n=1; Beggiatoa sp. PS|Rep: Metallo-beta-lactamase family protein - Beggiatoa sp. PS Length = 229 Score = 71.3 bits (167), Expect = 2e-11 Identities = 38/107 (35%), Positives = 58/107 (54%), Gaps = 1/107 (0%) Frame = +2 Query: 221 DLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKS 400 D ++ G ++ TPGHT G Y + TGDTL I GCGR DF E +Y S Sbjct: 107 DTIQLGKTDIEIWHTPGHTPGSACYYLDGHLI--TGDTLFIFGCGRCDFSGSEPEQMYHS 164 Query: 401 VHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL-TKSLAEFV 538 + LP E +++P H Y Q ++++AE+ + NP + ++A+FV Sbjct: 165 LKKIGTELPKETIIHPGHHYAHQPSSTLAEQLEGNPFMHFNNIADFV 211 >UniRef50_A5KQ31 Cluster: Putative uncharacterized protein; n=3; Clostridiales|Rep: Putative uncharacterized protein - Ruminococcus torques ATCC 27756 Length = 207 Score = 71.3 bits (167), Expect = 2e-11 Identities = 33/82 (40%), Positives = 46/82 (56%) Frame = +2 Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442 TPGHT G Y E+ + F+GDTL GRTD G+ L +SV ++ LP++ + Sbjct: 128 TPGHTEGGCCYYIGEEHVLFSGDTLFHNSIGRTDLPTGSGSELVRSVREKLLVLPEDTRV 187 Query: 443 YPAHDYRGQTATSVAEEKKYNP 508 YP H T+++ EKKYNP Sbjct: 188 YPGH----MEETTISHEKKYNP 205 >UniRef50_Q0W1G4 Cluster: Putative metallo-beta-lactamase; n=1; uncultured methanogenic archaeon RC-I|Rep: Putative metallo-beta-lactamase - Uncultured methanogenic archaeon RC-I Length = 460 Score = 71.3 bits (167), Expect = 2e-11 Identities = 44/130 (33%), Positives = 60/130 (46%), Gaps = 19/130 (14%) Frame = +2 Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQS------LAFTGDTLLIRGCGRTDFQ 370 L DGD + F +L TPGHT LTY+ ++Q FTGD L + GR D Sbjct: 91 LRDGDRITFDKLSILTMETPGHTPESLTYVLYDQKYPDEPLATFTGDALFVNSTGRIDLP 150 Query: 371 EGNSE-----TLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAE--------EKKYNPR 511 + N + LY S+H +I L D V+YPAH + + + EK+ NP Sbjct: 151 DENEKHVNAGKLYDSIHGKILPLGDHVVIYPAHGAGSVCGSGMGDRDWSTIGYEKRTNPH 210 Query: 512 LTKSLAEFVE 541 L EF+E Sbjct: 211 LQLGRDEFIE 220 >UniRef50_P54501 Cluster: Uncharacterized protein yqgX; n=10; Bacillaceae|Rep: Uncharacterized protein yqgX - Bacillus subtilis Length = 211 Score = 70.9 bits (166), Expect = 2e-11 Identities = 41/120 (34%), Positives = 60/120 (50%), Gaps = 1/120 (0%) Frame = +2 Query: 158 GTKSVIGKDSGAQADIHLLDGD-LVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDT 334 G+ + G + A+ HL++GD + G L TPGH+ G ++Y + L +GD Sbjct: 91 GSGMLRGIEVTAKPADHLIEGDGELNIGPFHLETLFTPGHSPGSVSYYVKDADLVISGDV 150 Query: 335 LLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 L G GRTD GN ETL S+H ++ TLP+ ++ H T V E+ NP L Sbjct: 151 LFQGGIGRTDLIGGNQETLLTSIHEKLLTLPEHTLVLSGHG----PETDVLTEQDQNPFL 206 >UniRef50_Q9JXH3 Cluster: Glyoxalase II family protein; n=5; Proteobacteria|Rep: Glyoxalase II family protein - Neisseria meningitidis serogroup B Length = 210 Score = 70.5 bits (165), Expect = 3e-11 Identities = 34/100 (34%), Positives = 49/100 (49%) Frame = +2 Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET 388 L +G+ + G + PGHT G + + C E L GD L GRTDF GN Sbjct: 113 LEEGETLTVGRYAFQVLHIPGHTPGHIVFYCAEAELLIAGDVLFYETIGRTDFPRGNHAD 172 Query: 389 LYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 L ++ N++FTLP+ + H TS+ EK++NP Sbjct: 173 LINNIRNKLFTLPETVQVVAGHG----RMTSIGHEKRHNP 208 >UniRef50_Q39KM6 Cluster: Beta-lactamase-like; n=36; Proteobacteria|Rep: Beta-lactamase-like - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 241 Score = 70.1 bits (164), Expect = 4e-11 Identities = 37/105 (35%), Positives = 52/105 (49%) Frame = +2 Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373 + D L DGD V+FG L PGHT G + + +A GD L GRTDF Sbjct: 133 EPDHWLSDGDTVQFGDETLEVYHCPGHTPGHVVFFSRAHRVAIVGDVLFAGSIGRTDFPR 192 Query: 374 GNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 GN E L +S+ +++ L D+ P H G +T +E++ NP Sbjct: 193 GNHEDLVRSIKEKLWPLGDDVTFVPGH---GPVST-FGDERRTNP 233 >UniRef50_A3DF45 Cluster: Beta-lactamase-like protein; n=1; Clostridium thermocellum ATCC 27405|Rep: Beta-lactamase-like protein - Clostridium thermocellum (strain ATCC 27405 / DSM 1237) Length = 201 Score = 70.1 bits (164), Expect = 4e-11 Identities = 38/103 (36%), Positives = 56/103 (54%) Frame = +2 Query: 197 ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376 AD L DG+++ G + TPGH+ G + + + FTGDTL G GRTDF +G Sbjct: 104 ADRLLKDGEVITVGGLDFEIIHTPGHSAGGICIKVGD--VVFTGDTLFCMGIGRTDFPDG 161 Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505 + TL S+ N++ L D V+YP H G+ T E K+++ Sbjct: 162 DLSTLLDSIKNKLMKLDDNVVVYPGH---GEPTTIGRERKEFS 201 >UniRef50_A6PUJ8 Cluster: Beta-lactamase domain protein; n=1; Victivallis vadensis ATCC BAA-548|Rep: Beta-lactamase domain protein - Victivallis vadensis ATCC BAA-548 Length = 205 Score = 69.3 bits (162), Expect = 6e-11 Identities = 44/117 (37%), Positives = 58/117 (49%), Gaps = 1/117 (0%) Frame = +2 Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET 388 L DG L+ FG + A TPGHT + Y + S FTGD L + GC S+ Sbjct: 93 LRDGQLLPFGETAVEAIFTPGHTRDSVCYRFADDSAVFTGDVLFV-GC----IGFCRSKE 147 Query: 389 LYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLT-KSLAEFVEIMDNL 556 +Y S+ +I L D V+Y HDY ++ EEKK NP L SL EF + +L Sbjct: 148 MYNSLMKKILPLADSLVVYSGHDYGPVPFRTLGEEKKLNPYLNCHSLEEFKAELQHL 204 >UniRef50_Q54EJ5 Cluster: Hydroxyacylglutathione hydrolase; n=1; Dictyostelium discoideum AX4|Rep: Hydroxyacylglutathione hydrolase - Dictyostelium discoideum AX4 Length = 292 Score = 69.3 bits (162), Expect = 6e-11 Identities = 44/128 (34%), Positives = 70/128 (54%), Gaps = 9/128 (7%) Frame = +2 Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIR--GCGRT 361 G+Q D D + GS ++ +TPGHT C++Y S+ F GDT+ + G R Sbjct: 120 GSQFDKLFTDDERFTIGSLQVRVISTPGHTPACVSYYIENDSV-FVGDTMFMPDVGTARC 178 Query: 362 DFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY----RGQT-ATSVAEEKKYNPRLTKSL 526 DF G++ETL+ S+ +I LP+ +Y HDY RG T T++AE++ N + S+ Sbjct: 179 DFPNGSAETLWTSM-KKILELPETVKVYVCHDYPPQERGITFFTTIAEQRLSNKHIKDSV 237 Query: 527 A--EFVEI 544 EF+++ Sbjct: 238 TKDEFIKM 245 >UniRef50_A1ID45 Cluster: Beta-lactamase-like; n=3; Bacteria|Rep: Beta-lactamase-like - Candidatus Desulfococcus oleovorans Hxd3 Length = 210 Score = 68.9 bits (161), Expect = 9e-11 Identities = 35/112 (31%), Positives = 61/112 (54%) Frame = +2 Query: 173 IGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGC 352 I ++ D + +GD++ FG+ E+ TPGH+ G ++ + ++ AF GDTL Sbjct: 100 IAAENSPPPDRTVKEGDVISFGTIEMKVLHTPGHSPGGISLVTDKK--AFVGDTLFAGSI 157 Query: 353 GRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 GRTDF G+ +TL ++ ++F L D+ +Y H T++ E++ NP Sbjct: 158 GRTDFPGGDFDTLISAIQTKLFPLGDDVTVYCGHG----PETTIGMERRTNP 205 >UniRef50_Q39ZZ6 Cluster: Metallo-beta-lactamase family protein; n=1; Pelobacter carbinolicus DSM 2380|Rep: Metallo-beta-lactamase family protein - Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) Length = 207 Score = 68.5 bits (160), Expect = 1e-10 Identities = 37/105 (35%), Positives = 54/105 (51%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D L DGD++ G + TPGHT +T H TGDTL + GR D + Sbjct: 92 DRSLADGDVLTVGDTAVEIVHTPGHTPADITL--HLPGALLTGDTLFVTKVGRADMAGSD 149 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 LY S+ R+ P E +++P HDY Q +++A E+++NP L Sbjct: 150 PAALYASLR-RLAAFPGETLVFPGHDYGPQPHSTIAFERQHNPYL 193 >UniRef50_A5FR77 Cluster: Beta-lactamase domain protein; n=3; Dehalococcoides|Rep: Beta-lactamase domain protein - Dehalococcoides sp. BAV1 Length = 217 Score = 68.5 bits (160), Expect = 1e-10 Identities = 35/103 (33%), Positives = 58/103 (56%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 DI L +G + G + + PGHT G + + + F+GDTL G GR+DF+E + Sbjct: 119 DIPLSEGSTLELGKIKFSVISIPGHTPGGICL--YTRGYLFSGDTLFNSGIGRSDFEESD 176 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 +E L +++ NR+ +LP E +++P H T++ +EK NP Sbjct: 177 TEALRQNIINRLLSLPPETLVFPGHG----RETTIGKEKTGNP 215 >UniRef50_A0UYT0 Cluster: Beta-lactamase-like; n=1; Clostridium cellulolyticum H10|Rep: Beta-lactamase-like - Clostridium cellulolyticum H10 Length = 208 Score = 68.5 bits (160), Expect = 1e-10 Identities = 40/113 (35%), Positives = 64/113 (56%), Gaps = 2/113 (1%) Frame = +2 Query: 176 GKDSGAQADIHLL-DGDLVRFGSHELLAAATPGHTNGCLTYICHE-QSLAFTGDTLLIRG 349 GK S ++ +L +G+ ++ G + TPGHT G IC + ++L F+GDTL G Sbjct: 96 GKASTFKSKYEILREGNSIKVGELDFKIIHTPGHTCGS---ICIQVENLLFSGDTLFKFG 152 Query: 350 CGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 GR D GN +Y S+ ++F LP E ++YP H G+ +T++ +E + NP Sbjct: 153 YGRVDLPNGNFSDIYNSIVEKLFILPGETIVYPGH---GE-STTITDEIRSNP 201 >UniRef50_Q9PFB0 Cluster: Beta-lactamase hydrolase-like protein; n=42; Proteobacteria|Rep: Beta-lactamase hydrolase-like protein - Xylella fastidiosa Length = 431 Score = 68.5 bits (160), Expect = 1e-10 Identities = 48/142 (33%), Positives = 73/142 (51%), Gaps = 10/142 (7%) Frame = +2 Query: 185 SGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGR 358 +G+Q D DGD+ GS + +PGHT +TY+ + AF DT+ + G R Sbjct: 257 NGSQWDHLFADGDVFNVGSIKGRVMFSPGHTLASVTYVIGD--TAFVHDTIFMPDAGTAR 314 Query: 359 TDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYR-----GQTATSVAEEKKYNPRLT-K 520 DF G++ L+ S+ I +LPDE L+ HDY+ + ++V E+KK NP L Sbjct: 315 ADFPGGSARALWSSIQT-ILSLPDETRLFTGHDYQPSGRHPRWESTVGEQKKANPHLAGV 373 Query: 521 SLAEFVEIMD--NLNLPYPKMI 580 FV + + + LP PK+I Sbjct: 374 DETTFVALREARDKTLPMPKLI 395 >UniRef50_Q9AAS7 Cluster: Hydroxyacylglutathione hydrolase, putative; n=4; cellular organisms|Rep: Hydroxyacylglutathione hydrolase, putative - Caulobacter crescentus (Caulobacter vibrioides) Length = 249 Score = 68.1 bits (159), Expect = 1e-10 Identities = 38/95 (40%), Positives = 51/95 (53%) Frame = +2 Query: 191 AQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQ 370 A D + DG+ V G L T GHT G ++Y E ++AF GDTL GCGR Sbjct: 86 APLDRVVRDGEEVMLGDTRLTVIDTGGHTLGHVSYYDAEDAIAFVGDTLFALGCGR--LF 143 Query: 371 EGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTA 475 EG +E ++ S+ R+ LPDE +Y AH+Y A Sbjct: 144 EGTAEQMWDSL-GRLIALPDETTVYCAHEYTASNA 177 >UniRef50_Q8EQ13 Cluster: Hypothetical conserved protein; n=1; Oceanobacillus iheyensis|Rep: Hypothetical conserved protein - Oceanobacillus iheyensis Length = 207 Score = 68.1 bits (159), Expect = 1e-10 Identities = 40/118 (33%), Positives = 60/118 (50%), Gaps = 1/118 (0%) Frame = +2 Query: 158 GTKSVIGKDSGAQ-ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDT 334 G+ +IG+ A AD + +G L G + TPGH+ G ++YI +Q + +GD Sbjct: 91 GSHKLIGESILATPADFSVDEGGLT-IGEFSMQVYHTPGHSPGSVSYIFPDQKIVISGDV 149 Query: 335 LLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 L RG GRTD G+ L S+ +++ LP EY + H T++ EEK NP Sbjct: 150 LFQRGIGRTDLPGGDLAILEHSIREKLYQLPGEYQVLSGHG----GITTIKEEKNENP 203 >UniRef50_Q81LX4 Cluster: Metallo-beta-lactamase family protein; n=14; Bacillus|Rep: Metallo-beta-lactamase family protein - Bacillus anthracis Length = 208 Score = 68.1 bits (159), Expect = 1e-10 Identities = 37/104 (35%), Positives = 52/104 (50%), Gaps = 1/104 (0%) Frame = +2 Query: 206 HLLDGD-LVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNS 382 H++D + + GS TPGH+ G ++Y C E S F+GD L GRTD G+ Sbjct: 108 HIIDAEGTLAIGSFNFEIFETPGHSPGSISYYCKEASAVFSGDVLFQMSIGRTDLPGGSF 167 Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 L S+ ++F LPDE + H TS+ EK+ NP L Sbjct: 168 AELIGSIEEKLFVLPDETAVLCGHG----PETSIGFEKENNPFL 207 >UniRef50_Q15XB6 Cluster: Beta-lactamase-like; n=1; Pseudoalteromonas atlantica T6c|Rep: Beta-lactamase-like - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 288 Score = 68.1 bits (159), Expect = 1e-10 Identities = 45/135 (33%), Positives = 74/135 (54%), Gaps = 11/135 (8%) Frame = +2 Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGRTDFQEGNS 382 L DG+ ++FGS L+ +TPGHT+ L+YI + F GDTL + G R DF G++ Sbjct: 124 LQDGESLQFGSATLVCMSTPGHTSDSLSYIIDDN--VFVGDTLFMPDGGTARCDFPGGDA 181 Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDYRG-----QTATSVAEEKKYNPRLTKSL--AEFVE 541 L+ S+ NR+ LP Y ++ HDY+ Q T+VA+ + N + + A++V Sbjct: 182 GLLWDSI-NRLHHLPAHYKIWVCHDYQPDNRELQYQTTVAQSQAANIHVNNQIDKAQYVA 240 Query: 542 IMD--NLNLPYPKMI 580 + + + L PK++ Sbjct: 241 LRNKRDATLAVPKLL 255 >UniRef50_A6DNT9 Cluster: Beta-lactamase-like protein; n=1; Lentisphaera araneosa HTCC2155|Rep: Beta-lactamase-like protein - Lentisphaera araneosa HTCC2155 Length = 213 Score = 68.1 bits (159), Expect = 1e-10 Identities = 38/108 (35%), Positives = 54/108 (50%), Gaps = 2/108 (1%) Frame = +2 Query: 191 AQADIHLLDGDLVRFGSHELLAAATPGHTNG--CLTYICHEQSLAFTGDTLLIRGCGRTD 364 A D + D FG +L A TPGH+ G C ++ L F+GDTL RG GRTD Sbjct: 106 ANVDHFIEDSQSFEFGEFKLEAIHTPGHSAGSTCFKIENSDEQLLFSGDTLFRRGVGRTD 165 Query: 365 FQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 G+S + KS+ +++ L + + P H T + EEK+ NP Sbjct: 166 LPSGDSREIAKSIKEKLYKLDIDTTVIPGHG----PNTVIGEEKRQNP 209 >UniRef50_Q1AWY9 Cluster: Beta-lactamase-like protein; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Beta-lactamase-like protein - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 214 Score = 67.7 bits (158), Expect = 2e-10 Identities = 36/105 (34%), Positives = 52/105 (49%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D ++ D + V G L A TPGH G L + + +GD L GRTD G+ Sbjct: 107 DGYIEDRERVEVGGLTLEALYTPGHAPGHLAFYLESEGALLSGDALFAGSVGRTDLPGGD 166 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 + L +S+ R+ LPDE V++P H T++ E+ YNP L Sbjct: 167 AGLLMRSIKERMLVLPDETVVHPGHG----PQTTIGNERAYNPFL 207 >UniRef50_Q11FA6 Cluster: Beta-lactamase-like; n=121; Proteobacteria|Rep: Beta-lactamase-like - Mesorhizobium sp. (strain BNC1) Length = 312 Score = 67.7 bits (158), Expect = 2e-10 Identities = 37/94 (39%), Positives = 51/94 (54%), Gaps = 2/94 (2%) Frame = +2 Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGRT 361 G+Q D DGD G+ ++ PGHT CL Y+ + F GDTL + G R Sbjct: 142 GSQFDHLFNDGDRFTIGNLDVTVLHVPGHTPACLAYVVGD--AVFPGDTLFMPDYGTARC 199 Query: 362 DFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYR 463 DF G++ LY+S+ R+F LPDE L+ HDY+ Sbjct: 200 DFPGGDARQLYRSI-KRLFQLPDEARLFLCHDYK 232 >UniRef50_A6PMC1 Cluster: Beta-lactamase domain protein; n=1; Victivallis vadensis ATCC BAA-548|Rep: Beta-lactamase domain protein - Victivallis vadensis ATCC BAA-548 Length = 201 Score = 67.7 bits (158), Expect = 2e-10 Identities = 33/81 (40%), Positives = 44/81 (54%) Frame = +2 Query: 266 PGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLY 445 PGHT G ++ E F GDT+ GRTDF G+ T+ S+ N I TLPDE +Y Sbjct: 122 PGHTPGGSGFLFRESPALFAGDTIFAGSIGRTDFPGGDFGTIIDSIRNGILTLPDELTIY 181 Query: 446 PAHDYRGQTATSVAEEKKYNP 508 P H + T+V E++ NP Sbjct: 182 PGHG----SQTTVGAERRSNP 198 >UniRef50_A2FLV6 Cluster: Metallo-beta-lactamase superfamily protein; n=2; Trichomonas vaginalis G3|Rep: Metallo-beta-lactamase superfamily protein - Trichomonas vaginalis G3 Length = 223 Score = 67.7 bits (158), Expect = 2e-10 Identities = 32/82 (39%), Positives = 46/82 (56%) Frame = +2 Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442 TPGHT G ++ L F+GDTL GR+DF G+ L + N + LPD+ V+ Sbjct: 138 TPGHTPGGACLYNKQEKLLFSGDTLFKDSIGRSDFPYGDGRQLVSGIVNNLMKLPDDTVV 197 Query: 443 YPAHDYRGQTATSVAEEKKYNP 508 +P H +T++ EE+KYNP Sbjct: 198 FPGHG----DSTTIGEERKYNP 215 >UniRef50_Q1MQL8 Cluster: Zn-dependent hydrolases, including glyoxylases; n=1; Lawsonia intracellularis PHE/MN1-00|Rep: Zn-dependent hydrolases, including glyoxylases - Lawsonia intracellularis (strain PHE/MN1-00) Length = 208 Score = 67.3 bits (157), Expect = 3e-10 Identities = 34/82 (41%), Positives = 44/82 (53%) Frame = +2 Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442 TPGHT G + E + FTGDTL GRTD N+ L+ S+H +IF LP ++ Sbjct: 129 TPGHTPGGVCLYFKEMNTLFTGDTLFYHTVGRTDLPGSNTNDLFTSLHKKIFVLPKYTIV 188 Query: 443 YPAHDYRGQTATSVAEEKKYNP 508 YP H + TS+ EE NP Sbjct: 189 YPGHGPK----TSIEEELTNNP 206 >UniRef50_A3M1P8 Cluster: Putative uncharacterized protein; n=1; Acinetobacter baumannii ATCC 17978|Rep: Putative uncharacterized protein - Acinetobacter baumannii (strain ATCC 17978 / NCDC KC 755) Length = 186 Score = 67.3 bits (157), Expect = 3e-10 Identities = 37/105 (35%), Positives = 52/105 (49%) Frame = +2 Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373 + D L G++++ G E PGHT G + + L +TGD L GRTDF Sbjct: 79 KVDQWLEGGEVLKLGEDEFEVRFAPGHTPGHVMFYNKNHGLLWTGDVLFKGSIGRTDFPR 138 Query: 374 GNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 GN E L +S+ F+LPDE H G +T + EK++NP Sbjct: 139 GNHEQLIESIQRECFSLPDETQFISGH---GPMST-IGYEKQFNP 179 >UniRef50_Q940L0 Cluster: Glyoxalase II; n=9; Magnoliophyta|Rep: Glyoxalase II - Oryza sativa (Rice) Length = 336 Score = 67.3 bits (157), Expect = 3e-10 Identities = 35/87 (40%), Positives = 47/87 (54%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 DI L +GD F H++L TPGHT+G + Y FTGDTL CG+ EG Sbjct: 170 DITLSEGDTWMFAGHQVLVMETPGHTSGHVCYHFPGSGAIFTGDTLFSLSCGK--LFEGT 227 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDY 460 + +Y S+ +I LPDE +Y H+Y Sbjct: 228 PQQMYSSL-QKIIALPDETRVYCGHEY 253 >UniRef50_Q5XD24 Cluster: Uncharacterized protein M6_Spy0554; n=45; Bacilli|Rep: Uncharacterized protein M6_Spy0554 - Streptococcus pyogenes serotype M6 Length = 232 Score = 67.3 bits (157), Expect = 3e-10 Identities = 32/88 (36%), Positives = 44/88 (50%) Frame = +2 Query: 245 ELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTL 424 E TPGH+ G ++++ H L TGD L GRTD N E L + +FTL Sbjct: 146 EFTVLPTPGHSWGGVSFVFHSDELVVTGDALFRETIGRTDLPTSNFEDLITGIRQELFTL 205 Query: 425 PDEYVLYPAHDYRGQTATSVAEEKKYNP 508 P+ Y +YP H +T++ EK NP Sbjct: 206 PNHYRVYPGHG----PSTTICHEKNANP 229 >UniRef50_A5Z3V7 Cluster: Putative uncharacterized protein; n=1; Eubacterium ventriosum ATCC 27560|Rep: Putative uncharacterized protein - Eubacterium ventriosum ATCC 27560 Length = 207 Score = 66.9 bits (156), Expect = 3e-10 Identities = 36/104 (34%), Positives = 52/104 (50%), Gaps = 1/104 (0%) Frame = +2 Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373 +AD L DG + + ATPGHT G Y + + F+GDTL GRTDF Sbjct: 107 EADEFLKDGQKITLAGINMTFIATPGHTPGSGCYYLEDNEILFSGDTLFHGSRGRTDFPG 166 Query: 374 GNSETLYKSVHNRIF-TLPDEYVLYPAHDYRGQTATSVAEEKKY 502 G+ + KS+ ++ LPDE + P H+ +T++ EK Y Sbjct: 167 GSESEIMKSIREKLLKKLPDETAVLPGHN----DSTTIGTEKVY 206 >UniRef50_Q5QUY0 Cluster: Zn-dependent hydrolases, glyoxylase family; n=6; Proteobacteria|Rep: Zn-dependent hydrolases, glyoxylase family - Idiomarina loihiensis Length = 292 Score = 66.1 bits (154), Expect = 6e-10 Identities = 41/114 (35%), Positives = 60/114 (52%), Gaps = 7/114 (6%) Frame = +2 Query: 185 SGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIR--GCGR 358 +G D L DG+ GS + TPGHT + Y+ +E + F GDTL G R Sbjct: 121 NGEHFDKLLQDGETFHLGSMTIRVIHTPGHTPADIAYVINENKV-FVGDTLFNPDVGTAR 179 Query: 359 TDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY-----RGQTATSVAEEKKYN 505 DF G++ TLY+S+ ++F L D +Y HDY + Q T+VA++K+ N Sbjct: 180 CDFPGGSANTLYRSI-QKLFELEDTTEVYICHDYPPEERQHQCKTTVADQKQNN 232 >UniRef50_Q3A304 Cluster: Putative uncharacterized protein; n=1; Pelobacter carbinolicus DSM 2380|Rep: Putative uncharacterized protein - Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) Length = 213 Score = 66.1 bits (154), Expect = 6e-10 Identities = 38/102 (37%), Positives = 49/102 (48%) Frame = +2 Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET 388 L DGD + GS L PGH+ G + C E F GD L GRTD G+ Sbjct: 114 LQDGDRIEVGSIVLEVLHVPGHSPGSVCLKCGEA--LFAGDVLFAGSIGRTDLPGGDHHL 171 Query: 389 LYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 L K + +R+ TL D +YP H AT++ E+K NP L Sbjct: 172 LLKGLQSRVLTLADSVKVYPGHG----PATTIGHERKNNPYL 209 >UniRef50_Q2RHV9 Cluster: Beta-lactamase-like; n=3; Clostridia|Rep: Beta-lactamase-like - Moorella thermoacetica (strain ATCC 39073) Length = 207 Score = 66.1 bits (154), Expect = 6e-10 Identities = 40/114 (35%), Positives = 56/114 (49%), Gaps = 1/114 (0%) Frame = +2 Query: 179 KDSGAQADIHLLDGDLVRFGSHELLAAA-TPGHTNGCLTYICHEQSLAFTGDTLLIRGCG 355 +++ AD L + D + G L TPGHT G + H + L FTGDTL G Sbjct: 100 REASPPADRLLEEDDTIAIGKTVTLRVIHTPGHTPGGICL--HGEGLVFTGDTLFAGSIG 157 Query: 356 RTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLT 517 RTDF G+ L S+ ++FTL D +YP H A+++ E+ NP T Sbjct: 158 RTDFPGGSYSQLISSIKEKLFTLDDALEVYPGHG----PASTIGAERVDNPFFT 207 >UniRef50_A6GG97 Cluster: Putative uncharacterized protein; n=1; Plesiocystis pacifica SIR-1|Rep: Putative uncharacterized protein - Plesiocystis pacifica SIR-1 Length = 226 Score = 66.1 bits (154), Expect = 6e-10 Identities = 35/111 (31%), Positives = 54/111 (48%), Gaps = 1/111 (0%) Frame = +2 Query: 203 IHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNS 382 + + DG+ V G + A PGHT GC+ + E TGD L + CG + + Sbjct: 105 VPVADGEDVAIGDGRMRAVYAPGHTPGCVCWYGPEAKALITGDVLFVGSCGGVSYPGSDP 164 Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATS-VAEEKKYNPRLTKSLAE 532 + ++ ++ +LP+E +YP HDY G+T TS + E NP L E Sbjct: 165 AAMVHTLQRKLGSLPEETRVYPGHDY-GKTPTSTLMWEFVNNPALLADTLE 214 >UniRef50_A3I369 Cluster: Metallo-beta-lactamase family protein; n=2; Flexibacteraceae|Rep: Metallo-beta-lactamase family protein - Algoriphagus sp. PR1 Length = 236 Score = 66.1 bits (154), Expect = 6e-10 Identities = 33/107 (30%), Positives = 52/107 (48%) Frame = +2 Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDF 367 G++ L +G+ + G +L PGH G + + + GDTL GRTD Sbjct: 126 GSEPSGFLEEGEFISVGKEKLKVLFVPGHAPGHVVFYHSDSKQLIAGDTLFRGSIGRTDL 185 Query: 368 QEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 GN E L + + + +F LPD+ V++P H T++ EK +NP Sbjct: 186 PGGNHELLLQKIKSELFNLPDQTVVFPGHG----PETNIGFEKVHNP 228 >UniRef50_A1UBD7 Cluster: Beta-lactamase domain protein; n=21; Actinomycetales|Rep: Beta-lactamase domain protein - Mycobacterium sp. (strain KMS) Length = 238 Score = 66.1 bits (154), Expect = 6e-10 Identities = 32/96 (33%), Positives = 55/96 (57%) Frame = +2 Query: 218 GDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYK 397 GD+V G ++ TPGHT G ++ + +A GDTL + GCGRTDF GN + +++ Sbjct: 129 GDVVSVGGIDIELLHTPGHTPGSQCFLLDGRLVA--GDTLFLEGCGRTDFPGGNVDDMFR 186 Query: 398 SVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505 S+ + LP + ++P H Y + + +++ K+ N Sbjct: 187 SL-QALAQLPGDPTVFPGHWYSAEPSDALSNVKRSN 221 >UniRef50_A0VLF2 Cluster: Hydroxyacylglutathione hydrolase; n=5; Bacteria|Rep: Hydroxyacylglutathione hydrolase - Dinoroseobacter shibae DFL 12 Length = 256 Score = 66.1 bits (154), Expect = 6e-10 Identities = 37/113 (32%), Positives = 53/113 (46%) Frame = +2 Query: 191 AQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQ 370 A D DGD F HE+ TPGHT + + + + FTGDTL + GCGR Sbjct: 88 AGVDTRYGDGDRFDFSGHEVRVIHTPGHTIDMINFYLPAEGVVFTGDTLFVMGCGR--LF 145 Query: 371 EGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLA 529 EG+ ++ S+ ++ LP + V+Y +H+Y A NP L A Sbjct: 146 EGDGPMMHASL-QKLAALPADTVIYCSHEYTEANADFALTVDPENPDLKDKAA 197 >UniRef50_A6TQP1 Cluster: Beta-lactamase domain protein; n=2; Clostridiaceae|Rep: Beta-lactamase domain protein - Alkaliphilus metalliredigens QYMF Length = 206 Score = 65.7 bits (153), Expect = 8e-10 Identities = 34/103 (33%), Positives = 56/103 (54%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D+ L DG+++ G+ +L TPGH+ G + + + FTGDTL GR+D + GN Sbjct: 107 DVFLKDGEVLTIGNLKLHVLHTPGHSPGGVCI--RGEGVVFTGDTLFANSIGRSDLEGGN 164 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 + L S+ +++ TL DE + P H A+++ E+ NP Sbjct: 165 YDQLIASIQSKLMTLDDELTVLPGHG----PASTIGIERMTNP 203 >UniRef50_A6TKP6 Cluster: Beta-lactamase domain protein; n=1; Alkaliphilus metalliredigens QYMF|Rep: Beta-lactamase domain protein - Alkaliphilus metalliredigens QYMF Length = 207 Score = 65.7 bits (153), Expect = 8e-10 Identities = 31/98 (31%), Positives = 49/98 (50%) Frame = +2 Query: 161 TKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLL 340 +K K+ D+ L GD + G+ +L TPGHT G + ++ + FTGDT+ Sbjct: 94 SKREYAKEVSITPDVLLSHGDTISVGALQLEVIHTPGHTPGSICLAVKDEKVIFTGDTVF 153 Query: 341 IRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAH 454 GRTD G+ L K++ N++ D+ +YP H Sbjct: 154 SDALGRTDLAGGSEAMLRKTIRNKVSKWDDDVRVYPGH 191 >UniRef50_A0Z233 Cluster: Putative uncharacterized protein; n=3; Proteobacteria|Rep: Putative uncharacterized protein - marine gamma proteobacterium HTCC2080 Length = 308 Score = 65.3 bits (152), Expect = 1e-09 Identities = 39/113 (34%), Positives = 58/113 (51%), Gaps = 7/113 (6%) Frame = +2 Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGRT 361 G+Q D DGD G+ A PGHT C+ Y+ ++ F GDTL + G R Sbjct: 115 GSQFDQIFADGDSFYLGNITCAAMHVPGHTPACMAYLLND--ALFVGDTLFMPDAGTARC 172 Query: 362 DFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQT-----ATSVAEEKKYN 505 DF GN+ L++S+ R+ TLP + ++ HDY+ T+VAE++ N Sbjct: 173 DFPGGNAHALFQSI-QRLLTLPGDTRIFVCHDYQPNDRPLAYETTVAEQRTLN 224 >UniRef50_A0HF94 Cluster: Beta-lactamase-like; n=6; cellular organisms|Rep: Beta-lactamase-like - Comamonas testosteroni KF-1 Length = 249 Score = 65.3 bits (152), Expect = 1e-09 Identities = 35/100 (35%), Positives = 48/100 (48%) Frame = +2 Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET 388 L DGD V G L PGHT G + + + AF GD L GRTDF +GN + Sbjct: 149 LHDGDTVTIGQETLNVRHCPGHTPGHVVFHSPQIDRAFVGDVLFAGSIGRTDFPQGNHQQ 208 Query: 389 LYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 L S+ R++ + D+ + P H +S E+K NP Sbjct: 209 LIDSIVQRLWPMGDQTIFIPGHG----PESSFGRERKLNP 244 >UniRef50_Q8KAV6 Cluster: Hydroxyacylglutathione hydrolase, putative; n=10; Chlorobiaceae|Rep: Hydroxyacylglutathione hydrolase, putative - Chlorobium tepidum Length = 215 Score = 64.9 bits (151), Expect = 1e-09 Identities = 39/133 (29%), Positives = 66/133 (49%), Gaps = 1/133 (0%) Frame = +2 Query: 158 GTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTL 337 G + ++ D A+ I ++ G G + TPGHT + + + FTGDTL Sbjct: 75 GIRVLLFGDRDARLGIEVMHGASFPLGEGVVEIIHTPGHTLDSICLLAGDA--LFTGDTL 132 Query: 338 LIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLT 517 + G T + E ++ Y+S+H R+ LP ++P HDY +++ EK NP L Sbjct: 133 FVGKVGGT-WSEADARLEYRSLHERLMVLPAGTNVFPGHDYGTAPVSTIGHEKTTNPFLL 191 Query: 518 KSLAE-FVEIMDN 553 + AE F+++ +N Sbjct: 192 QPDAESFIDLKNN 204 >UniRef50_Q8FYE7 Cluster: Hydroxyacylglutathione hydrolase, putative; n=19; Bacteria|Rep: Hydroxyacylglutathione hydrolase, putative - Brucella suis Length = 257 Score = 64.9 bits (151), Expect = 1e-09 Identities = 39/129 (30%), Positives = 57/129 (44%) Frame = +2 Query: 218 GDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYK 397 GD FG ++ +TPGHT G ++Y + + FTGDTL GCGR EG T++ Sbjct: 98 GDEFTFGLFKVKVISTPGHTAGGISYYLPDAKVVFTGDTLFALGCGR--LFEGTPATMFH 155 Query: 398 SVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNLNLPYPKM 577 S+ ++ LP + LY H+Y A N L + E + + + P Sbjct: 156 SL-EKLVALPGDTALYCGHEYTQNNARFALTIDPDNSALKERAKEIARLRAHERMTLPST 214 Query: 578 INKAGAGEP 604 I A P Sbjct: 215 IALEMATNP 223 >UniRef50_P64261 Cluster: Uncharacterized protein Rv2581c/MT2658; n=15; Actinomycetales|Rep: Uncharacterized protein Rv2581c/MT2658 - Mycobacterium tuberculosis Length = 224 Score = 64.9 bits (151), Expect = 1e-09 Identities = 34/105 (32%), Positives = 55/105 (52%), Gaps = 5/105 (4%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYIC-----HEQSLAFTGDTLLIRGCGRTDFQEGN 379 DGD + G + TPGHT G + + +++ + FTGDTL R GRTD G+ Sbjct: 119 DGDKIDLGGISVNIDHTPGHTRGSVVFRVLQATNNDKDIVFTGDTLFERAIGRTDLAGGS 178 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 L +S+ +++ L D V+ P H +T++ E+++NP L Sbjct: 179 GRDLLRSIVDKLLVLDDSTVVLPGHG----NSTTIGAERRFNPFL 219 >UniRef50_Q8N490 Cluster: Probable hydrolase PNKD; n=25; Euteleostomi|Rep: Probable hydrolase PNKD - Homo sapiens (Human) Length = 385 Score = 64.1 bits (149), Expect(2) = 2e-09 Identities = 35/85 (41%), Positives = 51/85 (60%), Gaps = 5/85 (5%) Frame = +2 Query: 221 DLVRFGSHELLAAATPGHTNGCLTYICHEQ-----SLAFTGDTLLIRGCGRTDFQEGNSE 385 D+V G ++ A ATPGHT G L Y+ + S F+GD L + GCGRT EGN+E Sbjct: 212 DVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRT--FEGNAE 269 Query: 386 TLYKSVHNRIFTLPDEYVLYPAHDY 460 T+ S+ + + L D+ +L+P H+Y Sbjct: 270 TMLSSL-DTVLGLGDDTLLWPGHEY 293 Score = 20.6 bits (41), Expect(2) = 2e-09 Identities = 7/18 (38%), Positives = 12/18 (66%) Frame = +2 Query: 461 RGQTATSVAEEKKYNPRL 514 +G +++ EE+ YNP L Sbjct: 326 KGTCPSTLGEERSYNPFL 343 >UniRef50_Q8N490-3 Cluster: Isoform 3 of Q8N490 ; n=8; Amniota|Rep: Isoform 3 of Q8N490 - Homo sapiens (Human) Length = 361 Score = 64.1 bits (149), Expect(2) = 2e-09 Identities = 35/85 (41%), Positives = 51/85 (60%), Gaps = 5/85 (5%) Frame = +2 Query: 221 DLVRFGSHELLAAATPGHTNGCLTYICHEQ-----SLAFTGDTLLIRGCGRTDFQEGNSE 385 D+V G ++ A ATPGHT G L Y+ + S F+GD L + GCGRT EGN+E Sbjct: 188 DVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPSCLFSGDLLFLSGCGRT--FEGNAE 245 Query: 386 TLYKSVHNRIFTLPDEYVLYPAHDY 460 T+ S+ + + L D+ +L+P H+Y Sbjct: 246 TMLSSL-DTVLGLGDDTLLWPGHEY 269 Score = 20.6 bits (41), Expect(2) = 2e-09 Identities = 7/18 (38%), Positives = 12/18 (66%) Frame = +2 Query: 461 RGQTATSVAEEKKYNPRL 514 +G +++ EE+ YNP L Sbjct: 302 KGTCPSTLGEERSYNPFL 319 >UniRef50_A4XU09 Cluster: Hydroxyacylglutathione hydrolase; n=2; Pseudomonadales|Rep: Hydroxyacylglutathione hydrolase - Pseudomonas mendocina ymp Length = 257 Score = 64.5 bits (150), Expect = 2e-09 Identities = 42/135 (31%), Positives = 60/135 (44%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D+ L D DL+ A PGHT G + Y EQ+L GDTL GCGR EG Sbjct: 88 DVDLGDNDLIEVLGLRFQIMAVPGHTLGHIAYYHAEQNLLLCGDTLFAGGCGR--LFEGT 145 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNLN 559 + +++S+ +R+ LP +Y H+Y + +NP ++ LAE D Sbjct: 146 PQQMHQSL-SRLAALPGATRVYCTHEYTLSNLRFAHAVEPHNPDVSARLAEVSRWRDEGR 204 Query: 560 LPYPKMINKAGAGEP 604 + P I A P Sbjct: 205 ISLPSSIELELATNP 219 >UniRef50_A7HGC5 Cluster: Beta-lactamase domain protein; n=2; Anaeromyxobacter|Rep: Beta-lactamase domain protein - Anaeromyxobacter sp. Fw109-5 Length = 217 Score = 64.1 bits (149), Expect = 2e-09 Identities = 36/103 (34%), Positives = 51/103 (49%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D H DG+ R G+ E TPGH+ G + ++ L F+GDTL GRTD G+ Sbjct: 107 DHHPGDGESFRVGASEGRVIHTPGHSPGSICLFFPQERLLFSGDTLFAGSVGRTDLPGGD 166 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 + L+ S+ ++F L D+ P H G V EE+ NP Sbjct: 167 FDALHASITGKLFPLGDDVRFLPGHGPAG----VVGEERLSNP 205 >UniRef50_A2DJY1 Cluster: Metallo-beta-lactamase superfamily protein; n=1; Trichomonas vaginalis G3|Rep: Metallo-beta-lactamase superfamily protein - Trichomonas vaginalis G3 Length = 248 Score = 64.1 bits (149), Expect = 2e-09 Identities = 37/112 (33%), Positives = 58/112 (51%) Frame = +2 Query: 227 VRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVH 406 + G L TPGHT G ++Y E GDT+ G T+ GN + L S+ Sbjct: 128 IDIGGDRLHIIETPGHTPGSISYYYPEGKWVVVGDTVFAGLIGSTNHYGGNKKQLVNSII 187 Query: 407 NRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNLNL 562 ++I TLPD+ V+YP H G+ +T V +EKK NP++ + + +D + + Sbjct: 188 SKILTLPDDTVIYPGH---GKNST-VKDEKK-NPQIIQFFKKNPPTIDQIKV 234 >UniRef50_Q41FV9 Cluster: Beta-lactamase-like; n=1; Exiguobacterium sibiricum 255-15|Rep: Beta-lactamase-like - Exiguobacterium sibiricum 255-15 Length = 205 Score = 63.7 bits (148), Expect = 3e-09 Identities = 32/100 (32%), Positives = 52/100 (52%) Frame = +2 Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET 388 L+ G L G + TPGH+ G +T+ ++ +AF GD + R GRTD + G+ + Sbjct: 109 LVSGSL-EIGPFQFHVLETPGHSPGSVTFYFKKEQVAFAGDLIFKRSVGRTDLEGGDQDV 167 Query: 389 LYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 L +S+ I +P + YP H T++ +E K+NP Sbjct: 168 LMRSIDRVIAEIPHDTTFYPGHG----PETTLRQEIKHNP 203 >UniRef50_A7IG57 Cluster: Beta-lactamase domain protein; n=1; Xanthobacter autotrophicus Py2|Rep: Beta-lactamase domain protein - Xanthobacter sp. (strain Py2) Length = 235 Score = 63.7 bits (148), Expect = 3e-09 Identities = 36/107 (33%), Positives = 51/107 (47%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D +L +G+ V G L PGHT G L ++ +A GDTL GRTDF G+ Sbjct: 133 DRYLSEGETVSVGDLTLDILHVPGHTPGHLVFVHKGVGIAIVGDTLFRGSVGRTDFPYGD 192 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTK 520 + L + ++ L D V P H TS+ +EK +NP L + Sbjct: 193 PDLLIAGIVGKLLPLGDNVVCLPGHG----PVTSIGDEKAHNPFLPR 235 >UniRef50_A7CUG8 Cluster: Beta-lactamase domain protein; n=1; Opitutaceae bacterium TAV2|Rep: Beta-lactamase domain protein - Opitutaceae bacterium TAV2 Length = 236 Score = 63.3 bits (147), Expect = 4e-09 Identities = 36/103 (34%), Positives = 51/103 (49%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D + GD +R E PGH G + + AF GD L GRTD G+ Sbjct: 134 DAVVTQGDRLRAFGIEAEVRHVPGHCPGNVLFYFAPMGAAFVGDALFAGSVGRTDLPGGS 193 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 SE L +SV +I+TLP+E ++P H T+V +E++ NP Sbjct: 194 SEQLARSVRTQIYTLPNETQVFPGHG----GPTTVGKERESNP 232 >UniRef50_Q97U88 Cluster: Putative uncharacterized protein; n=2; Sulfolobus|Rep: Putative uncharacterized protein - Sulfolobus solfataricus Length = 209 Score = 63.3 bits (147), Expect = 4e-09 Identities = 39/104 (37%), Positives = 51/104 (49%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394 +GD + G +L TPGHT G + I + FTGDTL GRTD G SE L Sbjct: 112 EGDEIELGGEKLKIIETPGHTMGSICIIAN--GYIFTGDTLFYGTVGRTDL--GGSEKLL 167 Query: 395 KSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSL 526 + ++ LPDE ++YP H T + EK NP LT + Sbjct: 168 RESLEKLKKLPDEIIVYPGHG----PFTVLGYEKVKNPFLTMDI 207 >UniRef50_Q5FU83 Cluster: Hydroxyacylglutathione hydrolase; n=1; Gluconobacter oxydans|Rep: Hydroxyacylglutathione hydrolase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 259 Score = 62.9 bits (146), Expect = 6e-09 Identities = 34/112 (30%), Positives = 54/112 (48%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394 DGD + GS ++ +TPGH G ++Y+ E F GD L GCGR EG ++ L+ Sbjct: 113 DGDSLSLGSAQIRVLSTPGHAVGHVSYVVPEVPALFCGDVLFSLGCGR--LLEGTAQELF 170 Query: 395 KSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMD 550 S+H R +LPD+ ++ H+Y N L E ++++ Sbjct: 171 DSLH-RYDSLPDQTLVCAGHEYTRSNLAFALHVDPDNAALKARAGEIEQLLE 221 >UniRef50_Q47LT8 Cluster: Putative hydrolase; n=1; Thermobifida fusca YX|Rep: Putative hydrolase - Thermobifida fusca (strain YX) Length = 209 Score = 62.9 bits (146), Expect = 6e-09 Identities = 34/87 (39%), Positives = 48/87 (55%) Frame = +2 Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373 + D LLDG++++ G+ EL TPG+T G + + FTGDTLL G ++ Sbjct: 110 EPDAPLLDGEVLQIGAVELEVRHTPGYTPGSVCLYVPALATVFTGDTLLGHGAS-GEYAP 168 Query: 374 GNSETLYKSVHNRIFTLPDEYVLYPAH 454 + ETL SV R+FTLP E +Y H Sbjct: 169 DDPETLRTSVAGRLFTLPPETTVYSGH 195 >UniRef50_Q5FRS6 Cluster: Metallo-beta-lactamase superfamily protein; n=1; Gluconobacter oxydans|Rep: Metallo-beta-lactamase superfamily protein - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 245 Score = 62.5 bits (145), Expect = 7e-09 Identities = 32/99 (32%), Positives = 50/99 (50%) Frame = +2 Query: 218 GDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYK 397 G+++ +L A PGHT G + ++ H+ GDTL GRTDF G+S+ L Sbjct: 149 GEVLHLLGQDLHVAHVPGHTPGHVVFVDHDNRRVLAGDTLFRGTVGRTDFAYGDSQALVD 208 Query: 398 SVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 + + TL D+ V+ H T++ EE++ NP L Sbjct: 209 GIRRHLLTLSDDTVVLCGHG----MPTTIGEERRTNPFL 243 >UniRef50_Q183H6 Cluster: Putative hydrolase; n=2; Clostridium difficile|Rep: Putative hydrolase - Clostridium difficile (strain 630) Length = 204 Score = 62.5 bits (145), Expect = 7e-09 Identities = 38/104 (36%), Positives = 54/104 (51%) Frame = +2 Query: 197 ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376 ADI++ D D + G ++ TPGHT GC+ ++ FTGDTL GRTD G Sbjct: 106 ADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDE--MFTGDTLFAGSIGRTDLYSG 163 Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 + + KS+ ++ D +YP H G T+T + EKK NP Sbjct: 164 DFNQMEKSL-KKLCKYEDAVRVYPGH---GPTST-LGVEKKTNP 202 >UniRef50_A4XI82 Cluster: Beta-lactamase domain protein; n=1; Caldicellulosiruptor saccharolyticus DSM 8903|Rep: Beta-lactamase domain protein - Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903) Length = 199 Score = 62.5 bits (145), Expect = 7e-09 Identities = 29/95 (30%), Positives = 49/95 (51%) Frame = +2 Query: 170 VIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRG 349 ++G + D + DGD++ FG TPGHT G ++ + + F+GDTL Sbjct: 93 IVGCEVTINCDEYFKDGDVLEFGDLNFKVIHTPGHTPGSSCFL-YGGDILFSGDTLFKDS 151 Query: 350 CGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAH 454 GR D G+ + +++S+ N++ TL +YP H Sbjct: 152 YGRCDLPLGDEKQIFESIKNKLLTLSKSTKVYPGH 186 >UniRef50_A1ZPC4 Cluster: Metallo-beta-lactamase family protein; n=1; Microscilla marina ATCC 23134|Rep: Metallo-beta-lactamase family protein - Microscilla marina ATCC 23134 Length = 217 Score = 62.5 bits (145), Expect = 7e-09 Identities = 30/103 (29%), Positives = 49/103 (47%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D+ + + D + FG+ L PGH G + ++ Q GD L GRTDF + Sbjct: 111 DVFVSEEDTIEFGNSSLEILFVPGHAPGHIAFLNRAQKFVINGDVLFKGSVGRTDFPGCS 170 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 E L S+ +++ L D+ +Y H T++ EK++NP Sbjct: 171 HEDLVNSIRTKMYALDDDVTVYTGHG----PETTIGYEKQFNP 209 >UniRef50_UPI00015BCB57 Cluster: UPI00015BCB57 related cluster; n=1; unknown|Rep: UPI00015BCB57 UniRef100 entry - unknown Length = 217 Score = 62.1 bits (144), Expect = 1e-08 Identities = 40/122 (32%), Positives = 57/122 (46%) Frame = +2 Query: 149 LVPGTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTG 328 L PG + + + D ++ DGD + S ++ TPGHT G + Q+ G Sbjct: 96 LFPGFSIYLNAKTPPKPDFYIKDGDKLSIASVDIEIIHTPGHTPGGCCFYLPSQNTLIAG 155 Query: 329 DTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 DTL G GRTD G+ E L KS+ LP + + H Y+ TS+ E K+NP Sbjct: 156 DTLFKGGVGRTDLPGGSWEDLSKSLKKIFSILPKDTHVICGH-YQD---TSLEHELKFNP 211 Query: 509 RL 514 L Sbjct: 212 FL 213 >UniRef50_Q0FEW8 Cluster: Putative hydroxyacylglutathione hydrolase (Glyoxalase II) (GLX II) protein; n=1; alpha proteobacterium HTCC2255|Rep: Putative hydroxyacylglutathione hydrolase (Glyoxalase II) (GLX II) protein - alpha proteobacterium HTCC2255 Length = 255 Score = 62.1 bits (144), Expect = 1e-08 Identities = 36/135 (26%), Positives = 61/135 (45%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 +I + GD++ G+ + TPGHT G ++Y + FTGD+L+ GCGR EG Sbjct: 90 NISVSTGDVISIGNQQAEILNTPGHTIGHISYFFKDSKKVFTGDSLMSLGCGR--LFEGT 147 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNLN 559 + ++ ++ LP E ++Y H+Y A N RL + E +++ + Sbjct: 148 HKMMWNTL-KLFMKLPKETLVYSGHEYSYSNAKFALSVDSSNTRLKEYYKEIQDLLKDNK 206 Query: 560 LPYPKMINKAGAGEP 604 P + A P Sbjct: 207 YTVPTSLELEFAINP 221 >UniRef50_A2R427 Cluster: Function: RSP29 precursor; n=20; Ascomycota|Rep: Function: RSP29 precursor - Aspergillus niger Length = 299 Score = 62.1 bits (144), Expect = 1e-08 Identities = 35/104 (33%), Positives = 53/104 (50%), Gaps = 3/104 (2%) Frame = +2 Query: 158 GTKSVIGKDSGAQADIHLLDGDLVRFGSH-ELLAAATPGHTNGCLTYICHE--QSLAFTG 328 G SVIG + G++ + G + A TP HT + Y + + FTG Sbjct: 122 GQLSVIGGKNCQSVTKTPAHGEVFKIGERISVKALHTPCHTQDSICYFMQDGDDKVVFTG 181 Query: 329 DTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460 DTL I GCGR F EG + ++K+++ + LPD+ +YP H+Y Sbjct: 182 DTLFIGGCGR--FFEGTAPEMHKALNETLAALPDDTKVYPGHEY 223 >UniRef50_Q7R4U1 Cluster: GLP_440_31929_31255; n=1; Giardia lamblia ATCC 50803|Rep: GLP_440_31929_31255 - Giardia lamblia ATCC 50803 Length = 224 Score = 61.3 bits (142), Expect = 2e-08 Identities = 27/66 (40%), Positives = 38/66 (57%) Frame = +2 Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442 TPGHT G C++ + FTGDT+ GRTDF G+S+ L SV L D++ + Sbjct: 141 TPGHTPGSSLLYCNKAKVVFTGDTIFANSVGRTDFPGGSSKQLKASVKRIYKELSDDFRI 200 Query: 443 YPAHDY 460 YP H++ Sbjct: 201 YPGHNH 206 >UniRef50_O94250 Cluster: Hydroxyacylglutathione hydrolase; n=1; Schizosaccharomyces pombe|Rep: Hydroxyacylglutathione hydrolase - Schizosaccharomyces pombe (Fission yeast) Length = 256 Score = 61.3 bits (142), Expect = 2e-08 Identities = 35/109 (32%), Positives = 56/109 (51%), Gaps = 2/109 (1%) Frame = +2 Query: 140 LKSLVPGTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQS-- 313 LK P G D + + L D + +R G+ ++ A TP HT + + H + Sbjct: 75 LKKEFPHVTIYGGSDQNGVSHV-LQDKETLRIGNVQIEALHTPCHTRDSICFYAHSSNEH 133 Query: 314 LAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460 FTGDTL GCGR F EG + ++ +++ + +LP+ V+YP H+Y Sbjct: 134 AVFTGDTLFNAGCGR--FFEGTAAEMHIALNAVLSSLPNNTVIYPGHEY 180 >UniRef50_Q60BX0 Cluster: Metallo-beta-lactamase family protein; n=9; Proteobacteria|Rep: Metallo-beta-lactamase family protein - Methylococcus capsulatus Length = 256 Score = 60.9 bits (141), Expect = 2e-08 Identities = 32/87 (36%), Positives = 49/87 (56%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D+ L DG+ R GS PGHT+G + + + + F GDTL GCGR EG+ Sbjct: 89 DVALKDGEEFRLGSASARMLDVPGHTSGHVAFWFEDDAALFCGDTLFALGCGR--LFEGS 146 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDY 460 +E +++S+ R+ LP E ++ AH+Y Sbjct: 147 AEQMWRSL-ERLRALPAETKVFCAHEY 172 >UniRef50_A5WFB5 Cluster: Hydroxyacylglutathione hydrolase; n=3; Psychrobacter|Rep: Hydroxyacylglutathione hydrolase - Psychrobacter sp. PRwf-1 Length = 259 Score = 60.9 bits (141), Expect = 2e-08 Identities = 38/112 (33%), Positives = 52/112 (46%), Gaps = 2/112 (1%) Frame = +2 Query: 131 LGKLKSLVPGTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQ 310 + +L+ L P T V + G + D + +G V + A PGHT L Y+ ++ Sbjct: 65 VAELRELYPMTHVVASAEHGVKPDQVVKEGSSVSAWGYTAQVWAVPGHTQSHLAYVLDKE 124 Query: 311 --SLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460 F GDTL GCGR G E L+ S R LPD + YPAH+Y Sbjct: 125 GHKQVFCGDTLFSAGCGRV--FTGTIEQLHDS-FKRFNKLPDNTLFYPAHEY 173 >UniRef50_Q54MR1 Cluster: Hydroxyacylglutathione hydrolase; n=1; Dictyostelium discoideum AX4|Rep: Hydroxyacylglutathione hydrolase - Dictyostelium discoideum AX4 Length = 268 Score = 60.9 bits (141), Expect = 2e-08 Identities = 34/105 (32%), Positives = 57/105 (54%), Gaps = 7/105 (6%) Frame = +2 Query: 167 SVIGKDSGAQADIHLLDG-DLVRFGSHELLAAATPGHTNGCLTYICHEQS------LAFT 325 +V G+D + L+ ++++ GS ++ P HT+ + Y+ +++ FT Sbjct: 76 NVYGRDERFEGITKKLENNEVLKIGSLKIKTLDAPAHTSSHVLYLIEDENEPNQVKSLFT 135 Query: 326 GDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460 GDTL I GCGR EGN E +Y +++N I LPD ++Y H+Y Sbjct: 136 GDTLFIGGCGR--LFEGNPEQMYNALYNVIGKLPDNTLVYVGHEY 178 >UniRef50_Q3IR18 Cluster: Homolog 4 to thiosulfate sulfurtransferase/ hydrolase (Probable hydroxyacylglutathione hydrolase) 2; n=1; Natronomonas pharaonis DSM 2160|Rep: Homolog 4 to thiosulfate sulfurtransferase/ hydrolase (Probable hydroxyacylglutathione hydrolase) 2 - Natronomonas pharaonis (strain DSM 2160 / ATCC 35678) Length = 388 Score = 60.9 bits (141), Expect = 2e-08 Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 6/92 (6%) Frame = +2 Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG---- 376 L ++V G +L A TPGHT+G +Y+ E +L TGDT+ + GRT+ Q G Sbjct: 217 LARNEVVTVGDVDLKAVFTPGHTSGMASYLVDENAL-LTGDTVFVDSVGRTELQFGAADA 275 Query: 377 --NSETLYKSVHNRIFTLPDEYVLYPAHDYRG 466 ++ LY+S+H I PD + P H + G Sbjct: 276 DTGAKLLYESLHGTILAEPDSVTVLPGHFHVG 307 >UniRef50_Q99KB8 Cluster: Hydroxyacylglutathione hydrolase; n=35; Eukaryota|Rep: Hydroxyacylglutathione hydrolase - Mus musculus (Mouse) Length = 260 Score = 60.9 bits (141), Expect = 2e-08 Identities = 40/114 (35%), Positives = 58/114 (50%), Gaps = 6/114 (5%) Frame = +2 Query: 137 KLKSLVPGTKSVIGKDSGAQADIHLLDG-DLVRFGSHELLAAATPGHTNGCLTYICH--- 304 KL L PG K V G D A H + ++ GS + +TP HT+G + Y Sbjct: 65 KLVKLEPGLK-VYGGDDRIGALTHKVTHLSTLQVGSLSVKCLSTPCHTSGHICYFVSKPG 123 Query: 305 --EQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460 E S FTGDTL + GCG+ F EG ++ +YK++ + LP + +Y H+Y Sbjct: 124 SSEPSAVFTGDTLFVAGCGK--FYEGTADEMYKALLEVLGRLPPDTKVYCGHEY 175 >UniRef50_Q82XW0 Cluster: Metallo-beta-lactamase superfamily; n=11; Proteobacteria|Rep: Metallo-beta-lactamase superfamily - Nitrosomonas europaea Length = 262 Score = 60.5 bits (140), Expect = 3e-08 Identities = 44/121 (36%), Positives = 59/121 (48%), Gaps = 2/121 (1%) Frame = +2 Query: 209 LLDGDLVRFG--SHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNS 382 L +GD + F S EL PGHT G + CH Q+ F GDTL GCGR EGN+ Sbjct: 88 LAEGDTLVFPELSLELSILDVPGHTAGHIA--CHGQNRLFCGDTLFACGCGR--IFEGNA 143 Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNLNL 562 + ++ S+ ++ LPDE +Y AH+Y NP L + L VE N+ Sbjct: 144 QQMFDSL-QKLTDLPDETQVYCAHEYTLDNIRFARAIDPDNPELIE-LESNVEEKREQNM 201 Query: 563 P 565 P Sbjct: 202 P 202 >UniRef50_Q6F9P0 Cluster: Putative hydroxyacylglutathione hydrolase; n=1; Acinetobacter sp. ADP1|Rep: Putative hydroxyacylglutathione hydrolase - Acinetobacter sp. (strain ADP1) Length = 244 Score = 60.1 bits (139), Expect = 4e-08 Identities = 38/117 (32%), Positives = 51/117 (43%) Frame = +2 Query: 230 RFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHN 409 +F + ATPGHT G + Y E F GDTL GCGR EG+ E +Y S+ N Sbjct: 103 KFNHLNVEVLATPGHTLGHVVYFIEETGSLFCGDTLFAMGCGRV--FEGSFEQMYHSL-N 159 Query: 410 RIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNLNLPYPKMI 580 R+ LP +Y H+Y A + N L + L E + + P I Sbjct: 160 RLAALPTTTKVYCTHEYTLANAEFAVTVEPDNLALKERLKEVQSLRSRHQITLPSTI 216 >UniRef50_Q2S0T9 Cluster: Metallo-beta-lactamase family protein; n=1; Salinibacter ruber DSM 13855|Rep: Metallo-beta-lactamase family protein - Salinibacter ruber (strain DSM 13855) Length = 216 Score = 60.1 bits (139), Expect = 4e-08 Identities = 35/108 (32%), Positives = 51/108 (47%), Gaps = 1/108 (0%) Frame = +2 Query: 206 HLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTD-FQEGNS 382 HL +GD V FG L TPGH+ ++++ A TGD L GRT E + Sbjct: 111 HLAEGDTVSFGDVTLEVLHTPGHSPDSISFVDRPGRQALTGDVLFQNSIGRTQGLPETSR 170 Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSL 526 L SV + L D+ +YP H AT++ E+ NP + ++L Sbjct: 171 AQLLNSVTETLLPLGDDVTIYPGHG----PATTIGRERAQNPFVQEAL 214 >UniRef50_A2DXP6 Cluster: Metallo-beta-lactamase superfamily protein; n=1; Trichomonas vaginalis G3|Rep: Metallo-beta-lactamase superfamily protein - Trichomonas vaginalis G3 Length = 222 Score = 60.1 bits (139), Expect = 4e-08 Identities = 31/101 (30%), Positives = 51/101 (50%) Frame = +2 Query: 206 HLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSE 385 ++ GD V G + TPG + G + YI ++ + FTG T++ G T F G++ Sbjct: 114 NIASGDEVSAGKYHFRVMETPGISPGSVIYILDDEEIVFTGMTIMKGIVGPTCFPYGDAG 173 Query: 386 TLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 LY S+ RI LP + +YP + + + ++EE NP Sbjct: 174 KLYTSIKERILVLPKNFAIYPGYGPK----SKISEEASTNP 210 >UniRef50_Q2SAD4 Cluster: Zn-dependent Hydrolase, including glyoxylases; n=5; Gammaproteobacteria|Rep: Zn-dependent Hydrolase, including glyoxylases - Hahella chejuensis (strain KCTC 2396) Length = 210 Score = 59.7 bits (138), Expect = 5e-08 Identities = 37/103 (35%), Positives = 50/103 (48%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D L +GD V G L PGHT G + + LA GD L GRTDF +G+ Sbjct: 108 DRWLNEGDEVSVGEETLQVLHCPGHTPGHVIFFHQGARLALVGDVLFNGSIGRTDFPKGD 167 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 TL +S+ +++ L D+ P H G +T A E+K NP Sbjct: 168 HATLIQSIKTKLWPLGDDVSFIPGH---GPMSTFGA-ERKTNP 206 >UniRef50_Q10LW8 Cluster: Hydroxyacylglutathione hydrolase, putative, expressed; n=3; Oryza sativa|Rep: Hydroxyacylglutathione hydrolase, putative, expressed - Oryza sativa subsp. japonica (Rice) Length = 258 Score = 59.7 bits (138), Expect = 5e-08 Identities = 45/149 (30%), Positives = 69/149 (46%), Gaps = 6/149 (4%) Frame = +2 Query: 137 KLKSLVPGTKSVIGK-DSGAQADIHLLDGDLVRFGSH-ELLAAATPGHTNGCLTYIC--- 301 K+ VPG K G D+ + +G + G E+L TP HT G ++Y Sbjct: 65 KMAQSVPGIKVYGGSLDNVKGCTDQVENGTKLSLGKDIEILCLHTPCHTKGHISYYVTSK 124 Query: 302 -HEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTAT 478 E FTGDTL I GCGR F EG +E +Y+S+ + +LP +Y H+Y + Sbjct: 125 EEEDPAVFTGDTLFIAGCGR--FFEGTAEQMYQSLCVTLGSLPKPTQVYCGHEYTVKNLK 182 Query: 479 SVAEEKKYNPRLTKSLAEFVEIMDNLNLP 565 + + N ++ + L E+ + N P Sbjct: 183 FILTVEPDNEKVKQKL-EWAQKQREANQP 210 >UniRef50_Q1IW29 Cluster: Beta-lactamase-like protein; n=4; Deinococci|Rep: Beta-lactamase-like protein - Deinococcus geothermalis (strain DSM 11300) Length = 219 Score = 59.3 bits (137), Expect = 7e-08 Identities = 33/105 (31%), Positives = 45/105 (42%), Gaps = 3/105 (2%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICH---EQSLAFTGDTLLIRGCGRTDFQ 370 D+ + G G L A PGH G + ++ E GDTL GRTD Sbjct: 115 DVEIAQGQTFTAGDLRLTARELPGHAPGHVVFVAQSGEEPGFVVAGDTLFQGSIGRTDLP 174 Query: 371 EGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505 GN L + + +LPDE +YP H AT+V E++ N Sbjct: 175 GGNHPQLIAGIRRELLSLPDETAIYPGHG----PATTVGAERRTN 215 >UniRef50_A6FTG4 Cluster: Beta-lactamase-like protein; n=1; Roseobacter sp. AzwK-3b|Rep: Beta-lactamase-like protein - Roseobacter sp. AzwK-3b Length = 306 Score = 59.3 bits (137), Expect = 7e-08 Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 2/84 (2%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLL--IRGCGRTDFQEGNSET 388 DGD + G+ ++ +PGHT G +TY+ + + AF DTL+ G R DF G+S Sbjct: 136 DGDTFKLGNLDVRVMLSPGHTLGSITYVVGDDA-AFVHDTLMHVDVGTSRADFPGGSSNE 194 Query: 389 LYKSVHNRIFTLPDEYVLYPAHDY 460 LY S+ I LPD+ L+ HDY Sbjct: 195 LYDSL-QAILALPDQTRLFIGHDY 217 >UniRef50_Q9XXJ1 Cluster: Putative uncharacterized protein; n=2; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 260 Score = 59.3 bits (137), Expect = 7e-08 Identities = 36/105 (34%), Positives = 56/105 (53%), Gaps = 8/105 (7%) Frame = +2 Query: 170 VIGKDSGAQA-DIHLLDGDLVRFGSHELLAAATPGHTNGCLTY-ICH------EQSLAFT 325 ++G DS A D H+ GD+ F ++ +TP HT+G + Y I + + FT Sbjct: 77 ILGGDSRIPAMDRHVKHGDMAEFAGLQIKCLSTPCHTSGHICYHITNPAADSTSPGVVFT 136 Query: 326 GDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460 GDTL I GCGR F EG + + +++ + LP E ++P H+Y Sbjct: 137 GDTLFIAGCGR--FFEGTAPQMDVALNEILKNLPVETQIFPGHEY 179 >UniRef50_Q9UT36 Cluster: Hydroxyacylglutathione hydrolase; n=10; Ascomycota|Rep: Hydroxyacylglutathione hydrolase - Schizosaccharomyces pombe (Fission yeast) Length = 256 Score = 59.3 bits (137), Expect = 7e-08 Identities = 37/109 (33%), Positives = 56/109 (51%), Gaps = 2/109 (1%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQS--LAFTGDTLLIRGCGRTDFQEGNSET 388 D ++ + G ++ A TP HT + Y S FTGDTL GCGR F EG+++ Sbjct: 99 DKEIFKVGEVQVEALHTPCHTQDSICYYVSSPSKRAVFTGDTLFTSGCGR--FFEGDAKQ 156 Query: 389 LYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEF 535 + ++++ + LPD+ V YP H+Y A + P LTK L +F Sbjct: 157 MDYALNHVLAALPDDTVTYPGHEYTKSNA-KFSSTIFSTPELTK-LVDF 203 >UniRef50_O67893 Cluster: Uncharacterized protein aq_2135; n=1; Aquifex aeolicus|Rep: Uncharacterized protein aq_2135 - Aquifex aeolicus Length = 211 Score = 59.3 bits (137), Expect = 7e-08 Identities = 35/117 (29%), Positives = 53/117 (45%) Frame = +2 Query: 158 GTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTL 337 G S IG + D+ + +GD++R G E TPGHT G ++ + GD L Sbjct: 91 GFASYIGAVPCPEPDVEISEGDVIRVGDVEFKVLHTPGHTPGLCCLYEEKRRVLIAGDLL 150 Query: 338 LIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 GR D GN L KSV + LP + ++ H T++ +E+ +NP Sbjct: 151 FKGSVGRWDLPGGNLVELKKSVKRVLTELPQDTLVICGH----YDETTIGQERAFNP 203 >UniRef50_A3CXZ9 Cluster: Beta-lactamase domain protein; n=1; Methanoculleus marisnigri JR1|Rep: Beta-lactamase domain protein - Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) Length = 467 Score = 58.8 bits (136), Expect = 9e-08 Identities = 46/141 (32%), Positives = 67/141 (47%), Gaps = 19/141 (13%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLA------FTGDTLLIRGCGRTDF--- 367 +G+ GS EL TPGHT ++ + ++S++ FTGD L GRTD Sbjct: 90 EGETFTVGSLELEILETPGHTIESISLLLRDRSVSGDPLMVFTGDALFAGDVGRTDLAGE 149 Query: 368 --QEGNSETLYKSVHNRIFTLPDEYVLYPAH--------DYRGQTATSVAEEKKYNPRLT 517 + SE LY S+H +I LPD ++ PAH + + T++ EK N L+ Sbjct: 150 DKRREMSEMLYASLHQKILPLPDSTIVCPAHGAGSVCGGNIGDREYTTIGFEKATNGLLS 209 Query: 518 KSLAEFVEIMDNLNLPYPKMI 580 S EFVE + L P+ I Sbjct: 210 LSKEEFVERKMSERLYEPQYI 230 >UniRef50_Q9HQ50 Cluster: Flavoprotein; n=4; Halobacteriaceae|Rep: Flavoprotein - Halobacterium salinarium (Halobacterium halobium) Length = 192 Score = 58.4 bits (135), Expect = 1e-07 Identities = 38/112 (33%), Positives = 54/112 (48%), Gaps = 4/112 (3%) Frame = +2 Query: 131 LGKLKSLVPG-TKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHE 307 +G L +LV +V+G D A AD L DGD +R G + + TPGH + Sbjct: 59 VGNLDALVDAFDPTVLGFDGVADADRALADGDEIRLGDDDYVVLHTPGHEPHHVCLYSPA 118 Query: 308 QSLAFTGDTLLIRGC-GRTDFQEGNSETLYKSVHNRIFTLPDEYV--LYPAH 454 + F+ D + G GRTD G+ ETL +S+ T+ E + LYP H Sbjct: 119 AGVLFSADLVFANGSFGRTDLDGGDRETLVESIDRLADTVAGEELTALYPGH 170 >UniRef50_UPI000049880A Cluster: metallo-beta-lactamase superfamily protein; n=1; Entamoeba histolytica HM-1:IMSS|Rep: metallo-beta-lactamase superfamily protein - Entamoeba histolytica HM-1:IMSS Length = 217 Score = 58.0 bits (134), Expect = 2e-07 Identities = 31/102 (30%), Positives = 50/102 (49%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D+ L GD + H+ + TPGH+ G ++ ++ + GDTL GRTD G+ Sbjct: 115 DVILKGGDEINLDGHKGVVLHTPGHSPGSCSFYFKDEEIVINGDTLFAGSYGRTDLWGGS 174 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505 L S+ N +F+LP ++ H + T++ E KK N Sbjct: 175 FAQLKASIKNVLFSLPLNTIVVTGHG----SNTTIREAKKSN 212 >UniRef50_Q0G3G4 Cluster: Putative uncharacterized protein; n=1; Fulvimarina pelagi HTCC2506|Rep: Putative uncharacterized protein - Fulvimarina pelagi HTCC2506 Length = 289 Score = 58.0 bits (134), Expect = 2e-07 Identities = 34/93 (36%), Positives = 50/93 (53%), Gaps = 2/93 (2%) Frame = +2 Query: 233 FGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET--LYKSVH 406 FGS + A TPGHT G ++Y + F+GDTL GCG +D + G ++ L++S+ Sbjct: 129 FGSIGIEALETPGHTAGSISY--RIGACLFSGDTLFSEGCGLSDPRNGGGDSGALFRSLD 186 Query: 407 NRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505 TLP E +YP H YR + A ++ N Sbjct: 187 ALRRTLPAECRIYPGHRYRQPIGRTFAALQRGN 219 >UniRef50_Q1HQH9 Cluster: Glyoxylase 3; n=3; Endopterygota|Rep: Glyoxylase 3 - Aedes aegypti (Yellowfever mosquito) Length = 302 Score = 58.0 bits (134), Expect = 2e-07 Identities = 28/82 (34%), Positives = 45/82 (54%), Gaps = 2/82 (2%) Frame = +2 Query: 221 DLVRFGSHELLAAATPGHTNGCLTYICH--EQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394 D + G+ ++ +TP HT + Y E + FTGDTL + GCGR F EG + +Y Sbjct: 142 DTLEIGNLKVRCISTPCHTTSHICYYIETPEDKVVFTGDTLFLAGCGR--FFEGTPQQMY 199 Query: 395 KSVHNRIFTLPDEYVLYPAHDY 460 ++ ++ LPD+ +Y H+Y Sbjct: 200 DALITKLSALPDDTKVYCGHEY 221 >UniRef50_Q5HP04 Cluster: Metallo-beta-lactamase family protein; n=18; Staphylococcus|Rep: Metallo-beta-lactamase family protein - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 207 Score = 57.6 bits (133), Expect = 2e-07 Identities = 26/64 (40%), Positives = 40/64 (62%) Frame = +2 Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442 TPGH+ G L+++ ++ A GDTL G GRTD +G+ ETL S+ +++F L + L Sbjct: 129 TPGHSPGSLSFVFND--FAVVGDTLFKNGIGRTDLYKGDYETLIDSIKDKLFELEGDMPL 186 Query: 443 YPAH 454 +P H Sbjct: 187 FPGH 190 >UniRef50_P75849 Cluster: Uncharacterized protein ycbL; n=120; Bacteria|Rep: Uncharacterized protein ycbL - Escherichia coli (strain K12) Length = 215 Score = 57.6 bits (133), Expect = 2e-07 Identities = 32/105 (30%), Positives = 51/105 (48%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D L +GD + G+ L PGHT G + + L +GD + G GR+DF G+ Sbjct: 108 DRWLNEGDTISIGNVTLQVLHCPGHTPGHVVFFDDRAKLLISGDVIFKGGVGRSDFPRGD 167 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 L S+ +++ L D+ + P H G +T + E+ +NP L Sbjct: 168 HNQLISSIKDKLLPLGDDVIFIPGH---GPLST-LGYERLHNPFL 208 >UniRef50_Q1D198 Cluster: Metallo-beta-lactamase family protein; n=1; Myxococcus xanthus DK 1622|Rep: Metallo-beta-lactamase family protein - Myxococcus xanthus (strain DK 1622) Length = 483 Score = 57.2 bits (132), Expect = 3e-07 Identities = 43/158 (27%), Positives = 77/158 (48%), Gaps = 22/158 (13%) Frame = +2 Query: 158 GTKSVIGKDS-GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYIC-----HEQSLA 319 G + V G+ AD+ + + + + G+ L+A TPGHT +++ H Q+ Sbjct: 71 GAQVVAGRHPITGHADVRMGERERLHLGALTLVALHTPGHTPESMSWAVYLDPHHAQAWG 130 Query: 320 -FTGDTLLIRGCGRTDFQEG-----NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATS 481 FTGD LL GRTD N+ L+ S+H ++ L D+ +++PAH + Sbjct: 131 VFTGDALLAGETGRTDLAAPERVYENAALLFDSLHQKVLPLGDQTLVFPAHGAGSVCRSG 190 Query: 482 VAE--------EKKYNPRLTKSLAEFVE--IMDNLNLP 565 +A+ E+ +NP T S ++F++ + + L+ P Sbjct: 191 IADRELTTLGFERLHNPVFTSSRSDFIQRKVQERLHRP 228 >UniRef50_UPI0000E49FBF Cluster: PREDICTED: hypothetical protein, partial; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein, partial - Strongylocentrotus purpuratus Length = 268 Score = 54.0 bits (124), Expect(2) = 4e-07 Identities = 38/114 (33%), Positives = 55/114 (48%), Gaps = 6/114 (5%) Frame = +2 Query: 137 KLKSLVPGTKSVIGKDSGAQADIHLL-DGDLVRFGSHELLAAATPGHTNGCLTYICHEQ- 310 KLKSL G+ G H L DGD + G + A TPGHT G + Y+ Sbjct: 65 KLKSLHSNLAVYGGERDGVPGCNHKLKDGDSFQIGGLKFTALFTPGHTVGHMVYLLDRSD 124 Query: 311 ----SLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460 + FTGD L + G GR EG + S+ ++I +PD+ +++P H+Y Sbjct: 125 KNLPNSLFTGDILFLGGNGR--MFEGPPSLMLSSL-DKICQIPDDTLVWPGHEY 175 Score = 22.6 bits (46), Expect(2) = 4e-07 Identities = 12/39 (30%), Positives = 20/39 (51%) Frame = +2 Query: 434 YVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMD 550 YV + R + +++ EEK YNP L S ++ +D Sbjct: 199 YVEERRKERRITSPSTLGEEKSYNPFLRTSQDSILQQVD 237 >UniRef50_Q9A911 Cluster: Glyoxalase II family protein; n=21; Proteobacteria|Rep: Glyoxalase II family protein - Caulobacter crescentus (Caulobacter vibrioides) Length = 273 Score = 56.8 bits (131), Expect = 4e-07 Identities = 36/103 (34%), Positives = 48/103 (46%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D L DGD V G E PGHT G + + E A GD L GRTDF GN Sbjct: 149 DRWLDDGDTVTLGETEFEVFHCPGHTPGHVVFFHRETKFAQVGDVLFQGSIGRTDFPMGN 208 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 + L S+ +++ L ++ P H G +T A E++ NP Sbjct: 209 HQDLIDSITQKLWPLGEDVRFVPGH---GPMSTFGA-ERRGNP 247 >UniRef50_Q89XT5 Cluster: Glyoxalase II; n=16; Alphaproteobacteria|Rep: Glyoxalase II - Bradyrhizobium japonicum Length = 255 Score = 56.8 bits (131), Expect = 4e-07 Identities = 33/118 (27%), Positives = 53/118 (44%) Frame = +2 Query: 191 AQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQ 370 A D+ + + D+V+ G+ TPGHT ++Y+ + F DTL GCGR Sbjct: 87 ANVDLRVANADVVKVGNLLARVVETPGHTLDHISYVFDTEKTVFAADTLFSIGCGRV--F 144 Query: 371 EGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEI 544 EG ++ S+ ++ LPD++ LY H+Y N L AE ++ Sbjct: 145 EGTYPMMWDSL-LKLRALPDDFKLYCGHEYTASNVKFALTVDPDNAALQARAAEVAKL 201 >UniRef50_Q73JL5 Cluster: Metallo-beta-lactamase family protein; n=1; Treponema denticola|Rep: Metallo-beta-lactamase family protein - Treponema denticola Length = 213 Score = 56.8 bits (131), Expect = 4e-07 Identities = 32/82 (39%), Positives = 45/82 (54%) Frame = +2 Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET 388 L DGD+V G L TPGHT G + + E + F+GDTL R GRTD G+ + Sbjct: 121 LKDGDIVN-GFKVLY---TPGHTEGSVCFWNEEAKVLFSGDTLFYRSHGRTDLLGGDDQK 176 Query: 389 LYKSVHNRIFTLPDEYVLYPAH 454 + S+ + + LPD+ +YP H Sbjct: 177 MKASLKS-LLNLPDDTTVYPGH 197 >UniRef50_Q2VZH9 Cluster: Zn-dependent hydrolase, including glyoxylase; n=2; Magnetospirillum|Rep: Zn-dependent hydrolase, including glyoxylase - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 270 Score = 56.8 bits (131), Expect = 4e-07 Identities = 28/86 (32%), Positives = 46/86 (53%) Frame = +2 Query: 203 IHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNS 382 + + +G+ G + PGHT+G + Y + + F GDTL GCGR EG + Sbjct: 105 LEVSEGETFMLGHAAVTVLEVPGHTSGHVAYWLADSHVLFCGDTLFSLGCGR--LFEGTA 162 Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDY 460 E ++ S+ ++ LP + + YPAH+Y Sbjct: 163 EEMWASL-KKLRDLPPDTLAYPAHEY 187 >UniRef50_Q1GEU3 Cluster: Hydroxyacylglutathione hydrolase; n=9; Rhodobacterales|Rep: Hydroxyacylglutathione hydrolase - Silicibacter sp. (strain TM1040) Length = 271 Score = 56.8 bits (131), Expect = 4e-07 Identities = 35/132 (26%), Positives = 58/132 (43%) Frame = +2 Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDF 367 G D+ L G G+ A PGHT G + + E F+ D+L++ GCGR Sbjct: 102 GVTLDMELEPGFEGGTGAGRCQVLAVPGHTLGHIAFYYPEAPALFSADSLMVMGCGR--L 159 Query: 368 QEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIM 547 EG +++++ + LPDE ++Y H+Y A + N L K + E + Sbjct: 160 FEGTPAMMWQTM-TTLSALPDETLIYSGHEYTESNAGFALSLEPENAALQKRMDEITKTR 218 Query: 548 DNLNLPYPKMIN 583 N P +++ Sbjct: 219 QNGQPTVPALLS 230 >UniRef50_A5WCY4 Cluster: Beta-lactamase domain protein; n=5; Proteobacteria|Rep: Beta-lactamase domain protein - Psychrobacter sp. PRwf-1 Length = 295 Score = 56.8 bits (131), Expect = 4e-07 Identities = 42/131 (32%), Positives = 61/131 (46%), Gaps = 13/131 (9%) Frame = +2 Query: 179 KDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHE-----QSLA-FTGDTLL 340 K +Q D +G G EL PGHT + YI Q LA F GDTL Sbjct: 112 KTDASQFDKLTEEGTQFMLGDIELTVMHVPGHTPADMAYIAKNTADTTQPLAIFVGDTLF 171 Query: 341 IR--GCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQ-----TATSVAEEKK 499 G R DF G+ + LY+S+ +I LP++ V+Y HDY Q T+V +K Sbjct: 172 APDVGTARVDFPGGDVDALYESIQ-KILALPEDTVIYLCHDYPPQDRTHSPVTTVGAQKA 230 Query: 500 YNPRLTKSLAE 532 +N + + +++ Sbjct: 231 HNIHVHQGISQ 241 >UniRef50_A3HIG2 Cluster: Beta-lactamase domain protein; n=18; Gammaproteobacteria|Rep: Beta-lactamase domain protein - Pseudomonas putida (strain GB-1) Length = 383 Score = 56.8 bits (131), Expect = 4e-07 Identities = 28/86 (32%), Positives = 45/86 (52%) Frame = +2 Query: 251 LAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPD 430 +A TPGHT G +++ + L GDTL RG GRTD G+ + +S+ R++ L + Sbjct: 298 VALHTPGHTPGSMSFWFADAKLLIAGDTLFRRGIGRTDLWGGDQRAIVRSIKERLYRLDE 357 Query: 431 EYVLYPAHDYRGQTATSVAEEKKYNP 508 E ++ H T + +E + NP Sbjct: 358 EAIVVTGHG----PDTRLGDEMRENP 379 >UniRef50_A7DEZ8 Cluster: Hydroxyacylglutathione hydrolase; n=2; Methylobacterium extorquens PA1|Rep: Hydroxyacylglutathione hydrolase - Methylobacterium extorquens PA1 Length = 158 Score = 56.4 bits (130), Expect = 5e-07 Identities = 28/66 (42%), Positives = 37/66 (56%) Frame = +2 Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442 TPGH +TY + + F+GDTL GCGR E ETL++S+ +R LPD + Sbjct: 13 TPGHCADHVTYYFADAGVVFSGDTLFTLGCGRV--MEAEPETLWRSL-SRFLDLPDATAV 69 Query: 443 YPAHDY 460 Y HDY Sbjct: 70 YSGHDY 75 >UniRef50_Q8Y5A2 Cluster: Lmo2167 protein; n=12; Listeria|Rep: Lmo2167 protein - Listeria monocytogenes Length = 205 Score = 56.0 bits (129), Expect = 6e-07 Identities = 29/82 (35%), Positives = 42/82 (51%) Frame = +2 Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442 TPGH+ G +++I E GD L GRTD G+ + L S+ ++F LPD++ Sbjct: 127 TPGHSIGSVSFIFDE--FVVVGDALFKGSIGRTDLYTGDFDMLINSIKTQLFVLPDDFPA 184 Query: 443 YPAHDYRGQTATSVAEEKKYNP 508 Y H T++ EKK NP Sbjct: 185 YSGHG----DVTTIGHEKKTNP 202 >UniRef50_Q5H3M1 Cluster: Beta-lactamase; n=8; Xanthomonadaceae|Rep: Beta-lactamase - Xanthomonas oryzae pv. oryzae Length = 296 Score = 56.0 bits (129), Expect = 6e-07 Identities = 44/145 (30%), Positives = 69/145 (47%), Gaps = 11/145 (7%) Frame = +2 Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI--RGCGRT 361 G+Q D D + G E A PGHT+ + Y+ + F GD+L + G R Sbjct: 138 GSQFDHLFADDERFLIGRIEARVVAVPGHTSDSIAYLIGD--ALFPGDSLFMPDAGTARC 195 Query: 362 DFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY-RGQTA----TSVAEEKKYNPRLTK-- 520 DF G++ L+ S+ R++ LPD ++ HDY G A TS+ E+++ N + Sbjct: 196 DFPGGDARQLFASI-QRLYALPDSTRVFVCHDYGPGGRAVAHQTSIGEQRRSNIHVRDGV 254 Query: 521 SLAEFVEIMD--NLNLPYPKMINKA 589 + FV + +LP PK+I A Sbjct: 255 DVETFVAQRQARDASLPEPKLIRPA 279 >UniRef50_A5G655 Cluster: Beta-lactamase domain protein; n=1; Geobacter uraniumreducens Rf4|Rep: Beta-lactamase domain protein - Geobacter uraniumreducens Rf4 Length = 233 Score = 56.0 bits (129), Expect = 6e-07 Identities = 29/95 (30%), Positives = 48/95 (50%) Frame = +2 Query: 221 DLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKS 400 D +R G + TPGHT G + Y+ SL FTGDT+ + GCG + G++ +++S Sbjct: 114 DQIRLGETLINCLLTPGHTTGSMCYLL-SHSL-FTGDTVFVEGCGICTTEGGSASGMFES 171 Query: 401 VHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505 + T+ ++P H Y S+A ++N Sbjct: 172 IQRIKRTVEPHVSVFPGHCYGRAPGCSLASVMEHN 206 >UniRef50_A1AVZ9 Cluster: Beta-lactamase domain protein; n=2; sulfur-oxidizing symbionts|Rep: Beta-lactamase domain protein - Ruthia magnifica subsp. Calyptogena magnifica Length = 240 Score = 56.0 bits (129), Expect = 6e-07 Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 4/123 (3%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394 + D + G+ TPGH+ G + Y+ +A GDTL + G G GN L+ Sbjct: 108 NNDTIFIGNTPAKIINTPGHSAGGICYLLDGHIIA--GDTLFVYGAGHCSLPGGNINELF 165 Query: 395 KSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP-RLTKSLAEFVEIMDNL---NL 562 S+ ++ + D +L+ HDY + T++ E+K+ N L + A+F+ ++++ + Sbjct: 166 HSMQ-KLKRIDDNVMLHCGHDYGSRVNTTMGEQKQGNAFLLIDNEADFLNYVNSMQQGKI 224 Query: 563 PYP 571 PYP Sbjct: 225 PYP 227 >UniRef50_Q5J7B5 Cluster: Glyoxalase IIB; n=9; Plasmodium|Rep: Glyoxalase IIB - Plasmodium falciparum Length = 263 Score = 56.0 bits (129), Expect = 6e-07 Identities = 37/141 (26%), Positives = 62/141 (43%), Gaps = 11/141 (7%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHE-----------QSLAFTGDTLLIRGCGRT 361 DG ++R G + A P HT G + Y ++ + + FTGDTL I GCGR Sbjct: 96 DGQIIRLGELNIKAIHAPCHTKGHILYYVYKTDEAKQEDHKYKPILFTGDTLFIAGCGR- 154 Query: 362 DFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVE 541 F EG+++ ++K++ ++ + E ++Y H+Y + N + L E E Sbjct: 155 -FFEGSAKDMFKNI-EKVKNMRKETLIYCGHEYTLNNLRFALSIENDNEYMKNKLNEVTE 212 Query: 542 IMDNLNLPYPKMINKAGAGEP 604 + N P I + P Sbjct: 213 KLKNKEHSVPSTIEEENLINP 233 >UniRef50_UPI00006CD179 Cluster: metallo-beta-lactamase superfamily protein; n=1; Tetrahymena thermophila SB210|Rep: metallo-beta-lactamase superfamily protein - Tetrahymena thermophila SB210 Length = 493 Score = 55.6 bits (128), Expect = 9e-07 Identities = 36/111 (32%), Positives = 49/111 (44%), Gaps = 12/111 (10%) Frame = +2 Query: 158 GTKSVIGKDSGAQADIHLL-DGDLVRFGSHELLAAATPGHTNGCLTYIC---HEQSLAFT 325 G K V G + A D HL DG+ + G + TPGHT Y+ Q FT Sbjct: 101 GAKIVYGPTAKASFDFHLATDGEKIPIGKVNIEVLHTPGHTQESSCYLLLDGERQHAVFT 160 Query: 326 GDTLLIRGCGRTDFQEGNSET--------LYKSVHNRIFTLPDEYVLYPAH 454 GDTL + GR D + E +Y S+ N+I L + ++YP H Sbjct: 161 GDTLFLGEVGRPDLAVKSGEITKEDLAGWMYDSLRNKIMKLDPKVIVYPGH 211 >UniRef50_Q1PVA8 Cluster: Similar to hydroxyacylglutathione hydrolase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Similar to hydroxyacylglutathione hydrolase - Candidatus Kuenenia stuttgartiensis Length = 189 Score = 55.6 bits (128), Expect = 9e-07 Identities = 37/115 (32%), Positives = 57/115 (49%) Frame = +2 Query: 164 KSVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI 343 KS G+ A+ L +++ G+ + A +TPGHT ++Y + FTGD L Sbjct: 79 KSYAGEGEVHSANNILQGSEIIEVGALQFKALSTPGHTLHGMSY--YIPGGVFTGDALFC 136 Query: 344 RGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 G T+ + + + +H IFTLPDE +++PAH T+V EK NP Sbjct: 137 GSVGGTNSSKA-VQCQTEHIHKHIFTLPDETLVFPAHG----PMTTVGIEKYTNP 186 >UniRef50_A0LDZ9 Cluster: Beta-lactamase domain protein; n=1; Magnetococcus sp. MC-1|Rep: Beta-lactamase domain protein - Magnetococcus sp. (strain MC-1) Length = 209 Score = 55.6 bits (128), Expect = 9e-07 Identities = 37/107 (34%), Positives = 52/107 (48%) Frame = +2 Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373 + D L G + +L TPGHT G + I +A GDTL G GRTD Sbjct: 107 EIDHPLTHGQRLELCGLQLEIIHTPGHTPGGVC-IRWGDEIA-VGDTLFAGGVGRTDLPG 164 Query: 374 GNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 G+ E L S+ R+ TL D+ V +P H +T++ +E+ NP L Sbjct: 165 GDHEQLMHSIETRLMTLGDDVVCHPGHG----ASTTIGQERMGNPFL 207 >UniRef50_A2FNK4 Cluster: Metallo-beta-lactamase superfamily protein; n=1; Trichomonas vaginalis G3|Rep: Metallo-beta-lactamase superfamily protein - Trichomonas vaginalis G3 Length = 212 Score = 55.6 bits (128), Expect = 9e-07 Identities = 31/100 (31%), Positives = 48/100 (48%), Gaps = 1/100 (1%) Frame = +2 Query: 203 IHLLD-GDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 +H ++ D ++FG PGHT G L + +L FTGDTL G T F GN Sbjct: 100 LHYVEKNDTIQFGDELFYIHTLPGHTPGGLGLYSQKHNLIFTGDTLFKSARGSTSFIGGN 159 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKK 499 + +S+++ +P +YP H T++A+E K Sbjct: 160 YTDMMQSLYDLFTYIPGNATVYPGH----YATTTIADEMK 195 >UniRef50_Q9UZT9 Cluster: Hydroxyacylglutathione hydrolase related; n=4; Thermococcaceae|Rep: Hydroxyacylglutathione hydrolase related - Pyrococcus abyssi Length = 222 Score = 55.6 bits (128), Expect = 9e-07 Identities = 25/70 (35%), Positives = 39/70 (55%) Frame = +2 Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373 + ++ L DGD ++ G +L TPGHT G E+ + FTGDT+ + GRTD Sbjct: 119 EVELKLEDGDEIKVGKVKLRLIHTPGHTRGSSCLYYEEERIMFTGDTVFLGTYGRTDLPT 178 Query: 374 GNSETLYKSV 403 GN + + +S+ Sbjct: 179 GNEDKIVESL 188 >UniRef50_Q8TPW0 Cluster: Metallo-beta-lactamase; n=3; cellular organisms|Rep: Metallo-beta-lactamase - Methanosarcina acetivorans Length = 481 Score = 55.6 bits (128), Expect = 9e-07 Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 10/94 (10%) Frame = +2 Query: 203 IHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQS------LAFTGDTLLIRGCGRTD 364 + L++GD + TPGHT ++Y+ + S F GDTL + GR D Sbjct: 87 VGLVEGDTFEIEDMTVKVLETPGHTPEHISYVVSDTSRGPDPTAVFCGDTLFVGDVGRPD 146 Query: 365 FQEGNSE----TLYKSVHNRIFTLPDEYVLYPAH 454 G + TLY S+H ++ +LPD +YPAH Sbjct: 147 LFPGKARELASTLYDSLHKKLLSLPDSCEVYPAH 180 >UniRef50_A0B5Y5 Cluster: Beta-lactamase domain protein; n=1; Methanosaeta thermophila PT|Rep: Beta-lactamase domain protein - Methanosaeta thermophila (strain DSM 6194 / PT) (Methanothrixthermophila (strain DSM 6194 / PT)) Length = 214 Score = 55.6 bits (128), Expect = 9e-07 Identities = 30/88 (34%), Positives = 47/88 (53%), Gaps = 1/88 (1%) Frame = +2 Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRG-CGRTDFQ 370 + D+ L DG ++ G L TPGH+ G + + + + F+GDT+ G GRTD Sbjct: 105 EVDMPLEDGMVLDLGDLRLEVIHTPGHSPGSMCFYERREGMLFSGDTVFPDGNIGRTDLF 164 Query: 371 EGNSETLYKSVHNRIFTLPDEYVLYPAH 454 G++E L +S+ R+ L D +YP H Sbjct: 165 GGSTEDLVRSI-ERLLELDDVSCMYPGH 191 >UniRef50_Q2LX15 Cluster: Hydroxyacylglutathione hydrolase; n=2; cellular organisms|Rep: Hydroxyacylglutathione hydrolase - Syntrophus aciditrophicus (strain SB) Length = 485 Score = 55.2 bits (127), Expect = 1e-06 Identities = 35/117 (29%), Positives = 57/117 (48%), Gaps = 17/117 (14%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQS----LAFTGDTLLIRGCGRTDF----- 367 DG + G +L A +PGHT G ++Y+ ++ + FTGD L GR DF Sbjct: 124 DGQTWKIGRLKLEAIHSPGHTPGSMSYLLYDADGNPWMVFTGDALFAGDVGRVDFLGEDR 183 Query: 368 QEGNSETLYKSVHNRIFTLPDEYVLYPAH--------DYRGQTATSVAEEKKYNPRL 514 + + LY ++H R+ L DE ++ H D + T++ E++YNP+L Sbjct: 184 MKKMAWLLYDTLHRRLLPLGDEVIVCAGHGAGSVCAGDISDRLWTTIGLERRYNPKL 240 >UniRef50_A7AQJ8 Cluster: Hydroxyacylglutathione hydrolase, putative; n=1; Babesia bovis|Rep: Hydroxyacylglutathione hydrolase, putative - Babesia bovis Length = 319 Score = 55.2 bits (127), Expect = 1e-06 Identities = 43/151 (28%), Positives = 72/151 (47%), Gaps = 8/151 (5%) Frame = +2 Query: 137 KLKSLVPGTKSVIGKDSGAQADIH--LLDGDLVRFGSHELLAAATPGHTNGCLTYICHE- 307 ++ ++PG V G ++ A + ++DGD+VR G E+ P HT G + Y Sbjct: 131 EMARIIPGIP-VYGSNNEDMAGMTNGIMDGDVVRLGGLEIKGVRVPCHTLGHMLYYVTNP 189 Query: 308 -----QSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQT 472 Q L FTGDT+ I GCGR F EG ++ + ++ N + + ++Y H+Y + Sbjct: 190 SDPTMQPLMFTGDTIFIGGCGR--FFEGTADMML-NIMNTVRQYRKDSLIYCGHEYTVKN 246 Query: 473 ATSVAEEKKYNPRLTKSLAEFVEIMDNLNLP 565 A +P + + + E+ E NLP Sbjct: 247 -LKFASTVDDSPAVKRKM-EWAESARQQNLP 275 >UniRef50_P0AC85 Cluster: Probable hydroxyacylglutathione hydrolase; n=40; Gammaproteobacteria|Rep: Probable hydroxyacylglutathione hydrolase - Escherichia coli O157:H7 Length = 251 Score = 55.2 bits (127), Expect = 1e-06 Identities = 31/82 (37%), Positives = 44/82 (53%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394 DG+ HE ATPGHT G + Y + F GDTL GCGR EG + +Y Sbjct: 91 DGETAFVLGHEFSVIATPGHTLGHICYF--SKPYLFCGDTLFSGGCGR--LFEGTASQMY 146 Query: 395 KSVHNRIFTLPDEYVLYPAHDY 460 +S+ ++ LPD+ ++ AH+Y Sbjct: 147 QSL-KKLSALPDDTLVCCAHEY 167 >UniRef50_O24495 Cluster: Hydroxyacylglutathione hydrolase 1, mitochondrial precursor; n=12; core eudicotyledons|Rep: Hydroxyacylglutathione hydrolase 1, mitochondrial precursor - Arabidopsis thaliana (Mouse-ear cress) Length = 331 Score = 55.2 bits (127), Expect = 1e-06 Identities = 32/93 (34%), Positives = 45/93 (48%) Frame = +2 Query: 167 SVIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIR 346 S + KD DI L D D F HE+ TPGHT G +++ + FTGD + Sbjct: 154 SAVDKDRIPGIDILLKDSDKWMFAGHEVRILDTPGHTQGHISFYFPGSATIFTGDLIYSL 213 Query: 347 GCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLY 445 CG EG E + S+ +I +LPD+ +Y Sbjct: 214 SCG--TLSEGTPEQMLSSL-QKIVSLPDDTNIY 243 >UniRef50_Q6MCN3 Cluster: Putative uncharacterized protein; n=1; Candidatus Protochlamydia amoebophila UWE25|Rep: Putative uncharacterized protein - Protochlamydia amoebophila (strain UWE25) Length = 468 Score = 54.8 bits (126), Expect = 1e-06 Identities = 41/128 (32%), Positives = 63/128 (49%), Gaps = 20/128 (15%) Frame = +2 Query: 191 AQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQS-------LAFTGDTLLIRG 349 A AD + + D++ FGS L TPGHT + +IC++++ F+GD L + Sbjct: 91 AYADHIVKEEDVLSFGSIRLKPLHTPGHTPEHIMWICYDETRSHDLPWFIFSGDCLFVGS 150 Query: 350 CGRTDFQEGN-----SETLYKSVHNRIFTLPDEYVLYPAH--------DYRGQTATSVAE 490 GR D N ++ LY+S+ RI LPD ++PAH + G AT++ Sbjct: 151 VGRPDLLGENAFNFLAKELYQSLFVRIAHLPDSVEVFPAHGAGSLCGKNIGGVDATTLGY 210 Query: 491 EKKYNPRL 514 E+ NP L Sbjct: 211 ERTCNPYL 218 >UniRef50_Q1GVB7 Cluster: Hydroxyacylglutathione hydrolase precursor; n=5; Sphingomonadaceae|Rep: Hydroxyacylglutathione hydrolase precursor - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 246 Score = 54.8 bits (126), Expect = 1e-06 Identities = 34/110 (30%), Positives = 49/110 (44%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D+ + GD VR G H P HT G + Y + + F GDT+ GCGR EG Sbjct: 95 DVLVKGGDTVRLGDHVADVWDVPAHTAGHIAYHFADDAAIFVGDTMFAMGCGR--LFEGT 152 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLA 529 +E ++ ++ ++ L D +Y AH+Y A N L LA Sbjct: 153 AEQMFANM-QKLRALDDATRVYCAHEYTLSNARFAITVDPANEALAARLA 201 >UniRef50_Q12BV7 Cluster: Hydroxyacylglutathione hydrolase; n=3; cellular organisms|Rep: Hydroxyacylglutathione hydrolase - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 263 Score = 54.8 bits (126), Expect = 1e-06 Identities = 35/99 (35%), Positives = 49/99 (49%), Gaps = 2/99 (2%) Frame = +2 Query: 170 VIGKDSGAQADIHLLDGDLVRFGSH-ELLAAATPGHTNGCLTYICH-EQSLAFTGDTLLI 343 + G D G +A GD+++ G EL TPGHT + H EQ F+GDTL Sbjct: 86 IAGVDRGVKA------GDVIKVGKTVELECLDTPGHTMCHICLRSHTEQPALFSGDTLFN 139 Query: 344 RGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460 G G G+ LY + ++ LPD+ ++YP HDY Sbjct: 140 AGAGNVH-NGGDVNALYATFAEQLARLPDDTLVYPGHDY 177 >UniRef50_Q01Q87 Cluster: Beta-lactamase domain protein; n=1; Solibacter usitatus Ellin6076|Rep: Beta-lactamase domain protein - Solibacter usitatus (strain Ellin6076) Length = 465 Score = 54.8 bits (126), Expect = 1e-06 Identities = 38/111 (34%), Positives = 56/111 (50%), Gaps = 12/111 (10%) Frame = +2 Query: 158 GTKSVIGKDSGAQ-ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICH--EQS----L 316 G +G ++GA + + DGD +RFG+ L TPGHT ++ + E+S Sbjct: 71 GADIYLGAEAGAAFPHVPVRDGDELRFGNCVLRFLETPGHTLESISILVTDLERSPDPYA 130 Query: 317 AFTGDTLLIRGCGRTDFQEGNSET-----LYKSVHNRIFTLPDEYVLYPAH 454 TGDTL I GR D ++ LY+S+ ++ TLPD +YPAH Sbjct: 131 VLTGDTLFIGDVGRPDLAPNHTPQQLAGMLYESLQKKLLTLPDGVEVYPAH 181 >UniRef50_A6G1T9 Cluster: Putative uncharacterized protein; n=1; Plesiocystis pacifica SIR-1|Rep: Putative uncharacterized protein - Plesiocystis pacifica SIR-1 Length = 214 Score = 54.8 bits (126), Expect = 1e-06 Identities = 40/104 (38%), Positives = 49/104 (47%), Gaps = 1/104 (0%) Frame = +2 Query: 206 HLLD-GDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNS 382 HLLD GD V G EL ATPGHT G Y E GDTL GRTDF + Sbjct: 111 HLLDDGDTVTLGELELTFVATPGHTPGQGCY--WEGDDIIVGDTLFAGSVGRTDFPMSDP 168 Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 S+ R+F LP ++ H T++A E++ NP L Sbjct: 169 SLARHSL-RRLFELPPHLRVHSGHG----PVTTLARERESNPFL 207 >UniRef50_Q8ZX02 Cluster: Conserved protein; n=4; Pyrobaculum|Rep: Conserved protein - Pyrobaculum aerophilum Length = 207 Score = 54.8 bits (126), Expect = 1e-06 Identities = 31/82 (37%), Positives = 43/82 (52%) Frame = +2 Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442 TPGHT G ++ + FTGD L R GRTD G+ E L +SV R++ LP + + Sbjct: 117 TPGHTPGSISLV--GDGFVFTGDALFYRSVGRTDLPYGDWEALVQSV-CRLYGLPPSFQV 173 Query: 443 YPAHDYRGQTATSVAEEKKYNP 508 YP H T++ E + NP Sbjct: 174 YPGHG----PETTIGAEARGNP 191 >UniRef50_A3VUN8 Cluster: Hydrolase; n=5; Proteobacteria|Rep: Hydrolase - Parvularcula bermudensis HTCC2503 Length = 451 Score = 54.4 bits (125), Expect = 2e-06 Identities = 39/118 (33%), Positives = 54/118 (45%), Gaps = 18/118 (15%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSL------AFTGDTLLIRGCGRTDFQEG 376 +GD G L TPGHT L+Y+ +++S FTGD L I GRTDF Sbjct: 92 EGDTFEIGGALLKVLETPGHTEDSLSYVLYDKSFEEGPVGVFTGDALFIGDVGRTDFYPD 151 Query: 377 NSE----TLYKSVHNRIFTLPDEYVLYPAH--------DYRGQTATSVAEEKKYNPRL 514 LY S+ ++ L D+ ++YPAH + +S+ EK NPRL Sbjct: 152 RKREVAGLLYDSL-EKLLGLGDQCLVYPAHGAGSVCGSGMADREFSSIGHEKLNNPRL 208 >UniRef50_A0M126 Cluster: Metallo-beta-lactamase/rhodanese-like domain protein; n=7; Bacteria|Rep: Metallo-beta-lactamase/rhodanese-like domain protein - Gramella forsetii (strain KT0803) Length = 476 Score = 54.4 bits (125), Expect = 2e-06 Identities = 41/144 (28%), Positives = 69/144 (47%), Gaps = 23/144 (15%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSL-----AFTGDTLLIRGCGRTDF---- 367 +GD FG +++A TPGHT L+Y+ +E TGD+L + GR D Sbjct: 105 EGDEFEFGQVKMMAKHTPGHTPEHLSYLLYESHKEDPWGIVTGDSLFVDSLGRPDLLGDE 164 Query: 368 -QEGNSETLYKSVHNRIFTLPDEYVLYPAH--------DYRGQTATSVAEEKKYNPRL-T 517 + ++ L+ ++ L DE ++YP H D + T++ EKK+NP + Sbjct: 165 KTDELTQALFNTMREVFCKLRDEVIVYPCHAAGSACGPDIGNRLHTTIGYEKKHNPFMQM 224 Query: 518 KSLAEFVEIMDNLNLP----YPKM 577 +++ EF + + + P YPKM Sbjct: 225 ETIEEFKKAVQDSAPPVPTHYPKM 248 >UniRef50_Q22PH1 Cluster: Metallo-beta-lactamase superfamily protein; n=1; Tetrahymena thermophila SB210|Rep: Metallo-beta-lactamase superfamily protein - Tetrahymena thermophila SB210 Length = 538 Score = 54.4 bits (125), Expect = 2e-06 Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 13/112 (11%) Frame = +2 Query: 158 GTKSVIGKDSGAQADIHLL-DGDLVRFGSHELLAAATPGHTNGCLTYICHEQS----LAF 322 G K + G + A DIH+ DG+ ++ G+ +L TPGHT ++ + + Sbjct: 153 GAKIIYGPGAQALYDIHVAKDGEEIQLGNIKLQVLHTPGHTTESSCFLLKDSKNQPHSVY 212 Query: 323 TGDTLLIRGCGRTDFQEGNSET--------LYKSVHNRIFTLPDEYVLYPAH 454 TGDTL + GR D + + L+ S+ N++ LPD +++P+H Sbjct: 213 TGDTLFLGEVGRPDLAVKSGQITEKDLAGMLFDSIKNKLLPLPDNVIVFPSH 264 >UniRef50_O54661 Cluster: Putative uncharacterized protein; n=1; Halobacterium salinarum|Rep: Putative uncharacterized protein - Halobacterium salinarium (Halobacterium halobium) Length = 369 Score = 54.4 bits (125), Expect = 2e-06 Identities = 43/134 (32%), Positives = 64/134 (47%), Gaps = 13/134 (9%) Frame = +2 Query: 179 KDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGR 358 KD+ A L DG V G ++ TPGH+ G +++ E + TGDTL GR Sbjct: 194 KDALAVDATPLEDGQTVTVGRLDIEVIHTPGHSEGSVSFDV-EGAALLTGDTLFHDSVGR 252 Query: 359 TDF----------QEGNSETLYKSVHNRIFTLPDEYVLYPAHD---YRGQTATSVAEEKK 499 + EGN+ TLY+S+ R+ PD+ ++ PAHD A ++AE ++ Sbjct: 253 VELGVEAGIEDADVEGNAATLYESL-QRLLDRPDDALVLPAHDPGSPEPPVAATLAEVRE 311 Query: 500 YNPRLTKSLAEFVE 541 N L + FVE Sbjct: 312 RNDDLGRDREAFVE 325 >UniRef50_Q8NQ06 Cluster: Zn-dependent hydrolases, including glyoxylases; n=4; Corynebacterium|Rep: Zn-dependent hydrolases, including glyoxylases - Corynebacterium glutamicum (Brevibacterium flavum) Length = 213 Score = 54.0 bits (124), Expect = 3e-06 Identities = 31/102 (30%), Positives = 49/102 (48%) Frame = +2 Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET 388 L+DG+ + E PGH+ GC + E F+GD L GRTDF+ +++ Sbjct: 115 LVDGETITLAGEEFTLKHAPGHSPGCTLIVGKEY--CFSGDVLFKGSIGRTDFEWSDADA 172 Query: 389 LYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 + +S+ + L D + P H G T T++ E+ NP L Sbjct: 173 MNESLRTAVLPLDDALQILPGH---GPT-TTMRAERTGNPFL 210 >UniRef50_Q8D376 Cluster: YcbL protein; n=1; Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis|Rep: YcbL protein - Wigglesworthia glossinidia brevipalpis Length = 214 Score = 54.0 bits (124), Expect = 3e-06 Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394 DGD+++ SHE PGH+ G + + Q++ +GD L G GR D G+ + Sbjct: 116 DGDIIKLDSHEFKVIHCPGHSPGHVAFWNKNQNILLSGDILFNNGIGRIDLPGGDKNKII 175 Query: 395 KSVHNRIFTL-PDEYVLYPAH 454 S+ N+I L +L P H Sbjct: 176 GSIKNKILKLCKKNIMLLPGH 196 >UniRef50_Q1V0X4 Cluster: Hydroxyacylglutathione hydrolase cytoplasmic; n=2; Candidatus Pelagibacter ubique|Rep: Hydroxyacylglutathione hydrolase cytoplasmic - Candidatus Pelagibacter ubique HTCC1002 Length = 239 Score = 54.0 bits (124), Expect = 3e-06 Identities = 41/137 (29%), Positives = 63/137 (45%), Gaps = 4/137 (2%) Frame = +2 Query: 167 SVIG----KDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDT 334 SVIG KD + DI + D D+ + + PGHT G + + + + FTGDT Sbjct: 73 SVIGYKGDKDRIPEIDILVGDQDIWHEENFQAKIFHIPGHTLGHICFYFYNEESVFTGDT 132 Query: 335 LLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 L GCG+ EG +Y S+ +I LP++ +Y H+Y Q + + N L Sbjct: 133 LFSLGCGK--IFEGTYSQMYNSL-MKIKALPEKTKIYCGHEYTKQNSKFCIAHDQDNENL 189 Query: 515 TKSLAEFVEIMDNLNLP 565 + E ++ NLP Sbjct: 190 KVKIKLIDEKLEK-NLP 205 >UniRef50_A0R0C8 Cluster: Metallo-beta-lactamase family protein; n=2; Corynebacterineae|Rep: Metallo-beta-lactamase family protein - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 210 Score = 54.0 bits (124), Expect = 3e-06 Identities = 33/97 (34%), Positives = 48/97 (49%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394 DG +++ G E+ A TPGH+ G + + E + +GDTL G G T + T+ Sbjct: 110 DGLVLKAGEIEVHALHTPGHSPGSVCWSIPELNAVISGDTLFQGGPGATGRSYSDFPTIL 169 Query: 395 KSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505 S+ NR+ LP E V+Y H G T T E Y+ Sbjct: 170 DSIKNRLGLLPAETVVYTGH---GDTTTIGGELVNYD 203 >UniRef50_Q8TNG7 Cluster: Metallo-beta-lactamase; n=3; Methanosarcina|Rep: Metallo-beta-lactamase - Methanosarcina acetivorans Length = 457 Score = 54.0 bits (124), Expect = 3e-06 Identities = 43/138 (31%), Positives = 62/138 (44%), Gaps = 20/138 (14%) Frame = +2 Query: 233 FGSHELLAAATPGHTNGCLTYIC------HEQSLAFTGDTLLIRGCGRTDFQEGN----- 379 FG+ +L A TPGHT+ ++Y+ E + FTGD L + GRTD Sbjct: 97 FGALKLTALHTPGHTDESMSYVLTDPDAGKEPIMVFTGDALFVGDVGRTDLYGPEEVPRL 156 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHD--------YRGQTATSVAEEKKYNPRLTKS-LAE 532 + LY S+ N+I L D +L PAH + +++ EK NP L K+ E Sbjct: 157 AANLYDSIFNKILPLGDGVILCPAHGAGSLCGGAISNREYSTLGLEKVQNPVLKKTEKEE 216 Query: 533 FVEIMDNLNLPYPKMINK 586 FV+ L +P K Sbjct: 217 FVKFKLEEKLEFPPYFKK 234 >UniRef50_Q6ML19 Cluster: Hydroxyacylglutathione hydrolase GloB; n=1; Bdellovibrio bacteriovorus|Rep: Hydroxyacylglutathione hydrolase GloB - Bdellovibrio bacteriovorus Length = 251 Score = 53.6 bits (123), Expect = 3e-06 Identities = 32/88 (36%), Positives = 44/88 (50%) Frame = +2 Query: 197 ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376 AD L +GD V G + PGHT G + Y + F+GD + GCGR EG Sbjct: 91 ADQWLKEGDSVTCGPWDFTVMELPGHTLGHIAYWNQKHKWLFSGDVIFGLGCGR--LFEG 148 Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDY 460 E Y+S+ RI LP + ++Y H+Y Sbjct: 149 TFEQGYESL-QRIKKLPPQTLIYCTHEY 175 >UniRef50_A4IPS9 Cluster: Metallo-beta-lactamase family protein; n=2; Geobacillus|Rep: Metallo-beta-lactamase family protein - Geobacillus thermodenitrificans (strain NG80-2) Length = 378 Score = 53.6 bits (123), Expect = 3e-06 Identities = 36/113 (31%), Positives = 60/113 (53%), Gaps = 6/113 (5%) Frame = +2 Query: 134 GKLKSLVPGTKSVIGKDSGAQADIHLLDG-DLVRFGS-H-ELLAAATPGHTNGCLTYICH 304 GK + G + K GA D L+ + + F + H E+LA TPGHT G +++ + Sbjct: 180 GKALAERTGAAYYLMKSEGAVFDFEPLEQHETIDFENVHLEVLAVKTPGHTPGSVSFFVN 239 Query: 305 EQSLAFTGDTLLIRGCGRTDF---QEGNSETLYKSVHNRIFTLPDEYVLYPAH 454 + L F+GDT+ + G GR D +E LY +V+ ++ + D+ ++ PAH Sbjct: 240 GKWL-FSGDTIFVGGLGRPDLGGKVAEWAEDLYHTVYEKVAAMADDVIVLPAH 291 >UniRef50_A3WQ55 Cluster: Probable hydroxyacylglutathione hydrolase GloB; n=1; Idiomarina baltica OS145|Rep: Probable hydroxyacylglutathione hydrolase GloB - Idiomarina baltica OS145 Length = 252 Score = 53.6 bits (123), Expect = 3e-06 Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 5/150 (3%) Frame = +2 Query: 131 LGKLKSLVPGTKSVIGKDSGA--QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICH 304 L LK+ P T G D+ A D +++GD V+ ATPGHT +++ + Sbjct: 62 LEALKARFPATS--YGPDNPAIKGIDYAVMEGDTVQIAGLRFDVLATPGHTLDHISF--Y 117 Query: 305 EQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSV 484 + F GDTL GCGR EG E L+ S +++ LP E ++ AH+Y T Sbjct: 118 GDTALFCGDTLFSGGCGR--MFEGTPE-LFVSSLDKLRRLPGETRVFCAHEYTQANLTFA 174 Query: 485 AEEKKYNPRLTKSLAEFVEIM---DNLNLP 565 + + N L KS E +++M D + LP Sbjct: 175 SLVEPDNAVL-KSYLEKIKLMRQNDQITLP 203 >UniRef50_Q22YX3 Cluster: Metallo-beta-lactamase superfamily protein; n=1; Tetrahymena thermophila SB210|Rep: Metallo-beta-lactamase superfamily protein - Tetrahymena thermophila SB210 Length = 524 Score = 53.6 bits (123), Expect = 3e-06 Identities = 34/113 (30%), Positives = 57/113 (50%), Gaps = 12/113 (10%) Frame = +2 Query: 152 VPGTKSVIGKDSGAQADIHLL-DGDLVRFGSHELLAAATPGHTNGCLTYICHEQS----L 316 + G V G + + +I + D +++ GS +L TPGHT Y+ +++ Sbjct: 81 ITGATIVFGPTASPKYEIKVASDEEILEIGSVKLQVLHTPGHTPESSCYLLLDENNTAQC 140 Query: 317 AFTGDTLLIRGCGRTDFQEGNSET-------LYKSVHNRIFTLPDEYVLYPAH 454 FTGDTL + GR D ++ T L+ S+ ++IF LP + ++YPAH Sbjct: 141 VFTGDTLFLGDVGRPDLACNSNVTKEDLAGQLFDSLRSKIFKLPRDIIVYPAH 193 >UniRef50_A6NCC4 Cluster: Uncharacterized protein HAGHL; n=24; Euteleostomi|Rep: Uncharacterized protein HAGHL - Homo sapiens (Human) Length = 291 Score = 53.6 bits (123), Expect = 3e-06 Identities = 36/114 (31%), Positives = 59/114 (51%), Gaps = 6/114 (5%) Frame = +2 Query: 137 KLKSLVPGTKSVIGKDSGA-QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYI----- 298 +L L PG +V+G D L G+ +RFG+ + TPGHT G ++Y Sbjct: 65 ELARLRPGL-AVLGADERIFSLTRRLAHGEELRFGAIHVRCLLTPGHTAGHMSYFLWEDD 123 Query: 299 CHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460 C + F+GD L + GCG EG+++ +Y+S+ + TLP E ++ H++ Sbjct: 124 CPDPPALFSGDALSVAGCG--SCLEGSAQQMYQSL-AELGTLPPETKVFCGHEH 174 >UniRef50_Q5KIL7 Cluster: Hydroxyacylglutathione hydrolase, putative; n=1; Filobasidiella neoformans|Rep: Hydroxyacylglutathione hydrolase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 274 Score = 53.6 bits (123), Expect = 3e-06 Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 5/113 (4%) Frame = +2 Query: 137 KLKSLVPGTKSVIGKDSGAQADIHLLDGDLVRFGSHELLAAA-TPGHTNGCLTYICHEQS 313 K SL P K G + + DGD G + TP HT + + ++ Sbjct: 88 KFLSLHPNLKVYAGSTQSPGTNTVVKDGDTFTLGQDITVKCLHTPCHTQDSICFFLEDKK 147 Query: 314 LA----FTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460 FTGDTL + GCGR F EG E ++ ++ ++ LP++ ++Y H+Y Sbjct: 148 TGQRGVFTGDTLFLAGCGR--FFEGTPEEMHAAL-TKLSNLPEDTIVYNGHEY 197 >UniRef50_UPI0000E244B7 Cluster: PREDICTED: similar to glyoxalase II, partial; n=1; Pan troglodytes|Rep: PREDICTED: similar to glyoxalase II, partial - Pan troglodytes Length = 284 Score = 53.2 bits (122), Expect = 5e-06 Identities = 38/114 (33%), Positives = 55/114 (48%), Gaps = 6/114 (5%) Frame = +2 Query: 137 KLKSLVPGTKSVIGKDSGAQADIHLLDG-DLVRFGSHELLAAATPGHTNGCLTYICH--- 304 KL L G K V G D A H + ++ GS + ATP HT+G + Y Sbjct: 8 KLVELQSGLK-VYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSKPG 66 Query: 305 --EQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460 E FTGDTL + GCG+ F EG ++ + K++ + LP + +Y H+Y Sbjct: 67 GSEPPAVFTGDTLFVAGCGK--FYEGTADEMCKALLEVLGRLPPDTRVYCGHEY 118 >UniRef50_A0DS29 Cluster: Chromosome undetermined scaffold_61, whole genome shotgun sequence; n=5; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_61, whole genome shotgun sequence - Paramecium tetraurelia Length = 483 Score = 53.2 bits (122), Expect = 5e-06 Identities = 46/176 (26%), Positives = 78/176 (44%), Gaps = 26/176 (14%) Frame = +2 Query: 152 VPGTKSVIGKDSGAQADIHLL-DGDLVRFGSHELLAAATPGHT--NGCLTYICHEQS-LA 319 + G + V+G + Q + D +L+ G L TPGHT + C + ++ + Sbjct: 91 ITGAQIVLGPQAVTQYQAKIAQDEELLPLGRAYLRVVHTPGHTLESSCFVLVVDDKDHVV 150 Query: 320 FTGDTLLIRGCGRTDFQEGNS--------ETLYKSVHNRIFTLPDEYVLYPAHDYRGQ-- 469 F+GD+L + GR D +S LY S+ N+I L D+ +LYP H Sbjct: 151 FSGDSLFLEEVGRPDLASKSSGLTTHQLASLLYHSLRNKIMKLEDDVILYPGHGAGSSCG 210 Query: 470 ------TATSVAEEKKYNPRLTK-SLAEFVEIMDNLNLP-----YPKMINKAGAGE 601 T +++ E+K N L + EFV+I ++ P + +N+ GA + Sbjct: 211 KAIGAGTVSTIGEQKLKNWALQNITEEEFVKISTDIPAPPQYFFHDVQLNRQGAND 266 >UniRef50_Q16775 Cluster: Hydroxyacylglutathione hydrolase; n=15; Eukaryota|Rep: Hydroxyacylglutathione hydrolase - Homo sapiens (Human) Length = 260 Score = 53.2 bits (122), Expect = 5e-06 Identities = 38/114 (33%), Positives = 55/114 (48%), Gaps = 6/114 (5%) Frame = +2 Query: 137 KLKSLVPGTKSVIGKDSGAQADIHLLDG-DLVRFGSHELLAAATPGHTNGCLTYICH--- 304 KL L G K V G D A H + ++ GS + ATP HT+G + Y Sbjct: 65 KLVKLESGLK-VYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSKPG 123 Query: 305 --EQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460 E FTGDTL + GCG+ F EG ++ + K++ + LP + +Y H+Y Sbjct: 124 GSEPPAVFTGDTLFVAGCGK--FYEGTADEMCKALLEVLGRLPPDTRVYCGHEY 175 >UniRef50_UPI0000F2E09A Cluster: PREDICTED: similar to myofibrillogenesis regulator 1; n=1; Monodelphis domestica|Rep: PREDICTED: similar to myofibrillogenesis regulator 1 - Monodelphis domestica Length = 286 Score = 52.8 bits (121), Expect = 6e-06 Identities = 33/103 (32%), Positives = 46/103 (44%), Gaps = 5/103 (4%) Frame = +2 Query: 221 DLVRFGSHELLAAATPGHTNGCLTYICHEQ-----SLAFTGDTLLIRGCGRTDFQEGNSE 385 D+V G + A ATPGHT G + Y+ + S F+GD L + GCG +E S Sbjct: 142 DMVSVGRLQFQALATPGHTRGHMVYVLDGEPYKGPSCLFSGDLLFLSGCGHEYSEENLSF 201 Query: 386 TLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 N ++V YR +++ EEK YNP L Sbjct: 202 AGLVEPENMAREKKMQWVQQQRLQYRSTCPSTLGEEKTYNPFL 244 >UniRef50_Q4JWL1 Cluster: Putative uncharacterized protein; n=1; Corynebacterium jeikeium K411|Rep: Putative uncharacterized protein - Corynebacterium jeikeium (strain K411) Length = 213 Score = 52.8 bits (121), Expect = 6e-06 Identities = 31/107 (28%), Positives = 52/107 (48%) Frame = +2 Query: 170 VIGKDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRG 349 ++ ++S A +D + R+ + TPGH+ GC+ Q +GDTL G Sbjct: 98 MLWEESNGDAPFTPIDVEDPRWADWGVRLYHTPGHSPGCIVVEVPGQHALLSGDTLFNGG 157 Query: 350 CGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAE 490 G T + + T+ +S+ +++F LP + +YP H G T T AE Sbjct: 158 PGATGRKYSSFPTIIESLQSKVFILPHDMKVYPGH---GDTTTVGAE 201 >UniRef50_A6FA17 Cluster: Hydroxyacylglutathione hydrolase; n=1; Moritella sp. PE36|Rep: Hydroxyacylglutathione hydrolase - Moritella sp. PE36 Length = 258 Score = 52.8 bits (121), Expect = 6e-06 Identities = 28/71 (39%), Positives = 42/71 (59%) Frame = +2 Query: 248 LLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLP 427 L ATPGH + Y + Q++ F+GDTL GCGR +G++ L+ S+ RI L Sbjct: 107 LTVMATPGHKREHVVY--YNQTMLFSGDTLFSGGCGR--LLDGSAAELFSSL-QRIKALD 161 Query: 428 DEYVLYPAHDY 460 + ++YPAH+Y Sbjct: 162 ENILVYPAHEY 172 >UniRef50_A4VLR2 Cluster: Hydroxyacylglutathione hydrolase; n=4; Proteobacteria|Rep: Hydroxyacylglutathione hydrolase - Pseudomonas stutzeri (strain A1501) Length = 292 Score = 52.8 bits (121), Expect = 6e-06 Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 2/130 (1%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYI--CHEQSLAFTGDTLLIRGCGRTDFQE 373 D L DG + L A PGHT G + Y +Q +GDTL GCGR E Sbjct: 121 DEALSDGQRIEVLGKRLQIIAVPGHTLGHIAYFHADPDQPWLLSGDTLFAAGCGR--LFE 178 Query: 374 GNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDN 553 G E +++S+ R+ + PD ++Y H+Y + +N + + E ++ + Sbjct: 179 GTPEQMFESL-TRLASAPDHTLVYCTHEYTLSNLRFAQAVEPHNADIAARIGEVTQLREA 237 Query: 554 LNLPYPKMIN 583 P ++ Sbjct: 238 GRFSLPSRLD 247 >UniRef50_A4E7W3 Cluster: Putative uncharacterized protein; n=1; Collinsella aerofaciens ATCC 25986|Rep: Putative uncharacterized protein - Collinsella aerofaciens ATCC 25986 Length = 229 Score = 52.8 bits (121), Expect = 6e-06 Identities = 35/102 (34%), Positives = 48/102 (47%), Gaps = 2/102 (1%) Frame = +2 Query: 209 LLDGDLVRFGSHELLAAATPGHT-NGCLTYICHEQ-SLAFTGDTLLIRGCGRTDFQEGNS 382 L +GD + G L TPGHT G + + EQ ++AF GDTL GRTD G+ Sbjct: 128 LAEGDTIELGDICLQVIETPGHTPGGIVLFAATEQGNIAFVGDTLFPGSHGRTDLSGGDE 187 Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 + S+ TLP + V H +T++A E NP Sbjct: 188 AAIMCSLSKLAKTLPPDTVCLTGHG----DSTTMARELMQNP 225 >UniRef50_UPI0000DAE586 Cluster: hypothetical protein Rgryl_01000658; n=1; Rickettsiella grylli|Rep: hypothetical protein Rgryl_01000658 - Rickettsiella grylli Length = 257 Score = 52.4 bits (120), Expect = 8e-06 Identities = 40/129 (31%), Positives = 59/129 (45%), Gaps = 1/129 (0%) Frame = +2 Query: 221 DLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKS 400 +L + S E+LA PGHT G + Y + L F GDTL GCGR EG + + S Sbjct: 98 ELTHWPSFEILAI--PGHTLGHIAY--YGNHLLFCGDTLFTAGCGR--LFEGTPDQMLNS 151 Query: 401 VHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNLNLP-YPKM 577 + ++ LPDE +Y H+Y + N + K L + E+ NLP P + Sbjct: 152 L-EKLAQLPDETQIYCGHEYTLANLNFAQTIEPDNTHIKKRLEKTRELRQK-NLPCVPSL 209 Query: 578 INKAGAGEP 604 + + P Sbjct: 210 LAEERLSNP 218 >UniRef50_Q8REE5 Cluster: Hydroxyacylglutathione hydrolase; n=3; Fusobacterium nucleatum|Rep: Hydroxyacylglutathione hydrolase - Fusobacterium nucleatum subsp. nucleatum Length = 207 Score = 52.4 bits (120), Expect = 8e-06 Identities = 35/117 (29%), Positives = 62/117 (52%), Gaps = 1/117 (0%) Frame = +2 Query: 167 SVIGKDSGAQADIHLL-DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLI 343 ++ G+ + +IH + + D+V G +++ TPGHT G ++ + + +GDTL Sbjct: 97 AIFGEFFKFKGEIHTVKESDMV--GDFKVID--TPGHTIGSKSFYYEKDKILISGDTLFR 152 Query: 344 RGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 R GR D G+ E L S+ ++ LPDE V+Y H T++ EE+++ R+ Sbjct: 153 RSYGRYDLPTGSLEMLCHSL-KKLSKLPDETVVYNGH----TDNTTIGEERRFLERV 204 >UniRef50_Q89VZ3 Cluster: Bll0900 protein; n=9; Rhizobiales|Rep: Bll0900 protein - Bradyrhizobium japonicum Length = 230 Score = 52.0 bits (119), Expect = 1e-05 Identities = 30/103 (29%), Positives = 45/103 (43%) Frame = +2 Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET 388 L +GD V G + PGH+ G + + E A GD L GRTD G+ T Sbjct: 129 LEEGDTVSIGGLQFDILHCPGHSPGSVAFFNKELRFAHVGDVLFAGSVGRTDLPGGSHAT 188 Query: 389 LYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLT 517 L S+ ++ L D+ H +S+ +E+ NP +T Sbjct: 189 LISSIKTKLLPLGDDVGFICGHG----AGSSIGQERMTNPFIT 227 >UniRef50_Q1RS81 Cluster: Hydroxyacylglutathione hydrolase; n=3; Bacillus|Rep: Hydroxyacylglutathione hydrolase - Bacillus amyloliquefaciens Length = 230 Score = 52.0 bits (119), Expect = 1e-05 Identities = 26/86 (30%), Positives = 42/86 (48%) Frame = +2 Query: 203 IHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNS 382 I L DG G + + TPGHT G + Y+ + FTGDT+ GCG + ++ Sbjct: 105 IALEDGQTFAAGGFIIRSILTPGHTAGGMCYLLSDH--LFTGDTVFTEGCGICGDRGSSA 162 Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDY 460 E ++ S+ ++P +YP H + Sbjct: 163 EDMFHSIQRIKASIPPHVRVYPGHSF 188 >UniRef50_Q04RQ6 Cluster: Zn-dependent hydrolase; n=3; Leptospira|Rep: Zn-dependent hydrolase - Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197) Length = 269 Score = 52.0 bits (119), Expect = 1e-05 Identities = 33/88 (37%), Positives = 47/88 (53%), Gaps = 4/88 (4%) Frame = +2 Query: 209 LLDGDLVRFGSHELLAAA-TPGHT--NGCLTYICHEQSLA-FTGDTLLIRGCGRTDFQEG 376 L GD + S E L TPGHT + CL + +++ A FTGDT+ G G G Sbjct: 93 LKKGDFLLRSSKEYLEILDTPGHTFCHVCLLLVENQKPKAIFTGDTIFNAGVGNCH-HGG 151 Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDY 460 + E L K++ + + L +E +LYP HDY Sbjct: 152 DPEVLAKTILEQFYPLEEEILLYPGHDY 179 >UniRef50_Q9YCJ7 Cluster: Putative uncharacterized protein; n=1; Aeropyrum pernix|Rep: Putative uncharacterized protein - Aeropyrum pernix Length = 209 Score = 52.0 bits (119), Expect = 1e-05 Identities = 28/85 (32%), Positives = 40/85 (47%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D+ L+DG +R L A TPGH+ + + LAFTGD + GR D G+ Sbjct: 104 DVELVDGSTLRAAGLSLKAIHTPGHSPDHIVLYDQARGLAFTGDLIFRGSIGRVDIALGD 163 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAH 454 E + +S+ + LP L P H Sbjct: 164 GEAMARSLARIVRELPRGTRLLPGH 188 >UniRef50_A7D114 Cluster: Beta-lactamase domain protein; n=4; Halobacteriaceae|Rep: Beta-lactamase domain protein - Halorubrum lacusprofundi ATCC 49239 Length = 402 Score = 52.0 bits (119), Expect = 1e-05 Identities = 43/142 (30%), Positives = 62/142 (43%), Gaps = 7/142 (4%) Frame = +2 Query: 200 DIHLL-DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376 D+ L+ DGD G + TPGHT G +Y+ + LA TGD L I R D +EG Sbjct: 224 DVTLVEDGDEFTVGDATVETVFTPGHTTGMTSYLLGDSLLA-TGDGLFIESVARPDLEEG 282 Query: 377 N------SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFV 538 + + LY S+ R+ +L D ++ AH S A E + T + E Sbjct: 283 DDGAPEAARMLYDSLQTRVLSLDDNVLVGGAH-------FSDAAEPAADGTYTAPIGELR 335 Query: 539 EIMDNLNLPYPKMINKAGAGEP 604 E MD L+ + + A P Sbjct: 336 ERMDALSADEDEFVETVLADMP 357 >UniRef50_Q2LSA2 Cluster: Zn-dependent hydrolases; n=1; Syntrophus aciditrophicus SB|Rep: Zn-dependent hydrolases - Syntrophus aciditrophicus (strain SB) Length = 215 Score = 51.6 bits (118), Expect = 1e-05 Identities = 32/87 (36%), Positives = 47/87 (54%) Frame = +2 Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373 + DI L +G+L G+ +TPGH+ G L E+ + F+GD +G GR+D Sbjct: 107 EPDILLQEGEL-DIGTVRFQVISTPGHSPGSLCLYWPERKVLFSGDVAFDQGIGRSDLPG 165 Query: 374 GNSETLYKSVHNRIFTLPDEYVLYPAH 454 GN + L +S+ RI L EY+L P H Sbjct: 166 GNGKLLKESL-RRIAQLDVEYLL-PGH 190 >UniRef50_Q1K398 Cluster: Hydroxyacylglutathione hydrolase; n=1; Desulfuromonas acetoxidans DSM 684|Rep: Hydroxyacylglutathione hydrolase - Desulfuromonas acetoxidans DSM 684 Length = 249 Score = 51.6 bits (118), Expect = 1e-05 Identities = 29/66 (43%), Positives = 34/66 (51%) Frame = +2 Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442 TPGHT G Y + F GDTL GCGR EG E LY S+ +I LP+ L Sbjct: 105 TPGHTRGDCCYYLPQCEALFCGDTLFSGGCGRV--FEGTMEQLYHSL-QKITALPETTRL 161 Query: 443 YPAHDY 460 Y H+Y Sbjct: 162 YCGHEY 167 >UniRef50_A4W8U6 Cluster: Beta-lactamase domain protein; n=11; Gammaproteobacteria|Rep: Beta-lactamase domain protein - Enterobacter sp. 638 Length = 215 Score = 51.6 bits (118), Expect = 1e-05 Identities = 31/105 (29%), Positives = 50/105 (47%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D L +G+ V G+ L PGHT G + + + L +GD + G GR+DF G+ Sbjct: 108 DRWLNEGESVNVGNVTLQILHCPGHTPGHIVFFDDQSRLLISGDVIFKGGVGRSDFPRGD 167 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 L +S+ ++ L D+ H G +T + E+ +NP L Sbjct: 168 HGQLIQSIKQKLLPLGDDVTFIAGH---GPMST-LGYERLHNPFL 208 >UniRef50_Q4PH24 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 268 Score = 51.6 bits (118), Expect = 1e-05 Identities = 36/100 (36%), Positives = 50/100 (50%), Gaps = 5/100 (5%) Frame = +2 Query: 203 IHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHE----QSLAFTGDTLLIRGCGRTDFQ 370 +H D G + ATP HT + Y + QS FTGDTL I GCGR F Sbjct: 92 VHDADRISELLGGVSIECVATPCHTQDHICYHVTDTTTAQSGVFTGDTLFISGCGR--FF 149 Query: 371 EGNSETLYKSVHNRIFTLPDEYVLYPAHDY-RGQTATSVA 487 EG+ + + S +R+ +LPD ++Y H+Y + A S A Sbjct: 150 EGHPQQML-SAMDRLSSLPDHTLVYCGHEYTKSNVAFSAA 188 >UniRef50_Q4JCD2 Cluster: Conserved protein; n=1; Sulfolobus acidocaldarius|Rep: Conserved protein - Sulfolobus acidocaldarius Length = 198 Score = 51.6 bits (118), Expect = 1e-05 Identities = 38/105 (36%), Positives = 53/105 (50%), Gaps = 4/105 (3%) Frame = +2 Query: 212 LDGDL----VRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 +DGDL + FG + TPGHT G ++++ + FTGDTL GR D G+ Sbjct: 96 VDGDLKEGVINFGKILVKVIETPGHTLGSVSFMIEDN--LFTGDTLFNENIGRYDL-GGD 152 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRL 514 E L KS+ R+ L D +YP H + T++ EK NP L Sbjct: 153 REYLKKSL-RRLMDLEDLLNVYPGHGF----ITTLGYEKLNNPFL 192 >UniRef50_Q488C8 Cluster: Aminotransferase, class V; n=5; Alteromonadales|Rep: Aminotransferase, class V - Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibriopsychroerythus) Length = 778 Score = 51.2 bits (117), Expect = 2e-05 Identities = 37/145 (25%), Positives = 65/145 (44%), Gaps = 11/145 (7%) Frame = +2 Query: 143 KSLVPGTKSVIGKDSGAQAD-IHLLDGDLVRFGSHELLAAATPGHTNGCLTYI-CH---- 304 K L +G +GAQ IH + G L+ ATPGHT+ ++ + C Sbjct: 500 KFLAEQQTEYLGWPAGAQTTTIHGQTFQYLILGDKWLIKVATPGHTDDSMSLLLCDPVTD 559 Query: 305 -----EQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQ 469 + AF GD +L+ GR++F ++ +Y S+ + + ++ P+HDY + Sbjct: 560 SAEKLQVHYAFCGDLILMDSIGRSNFSTSSAPAMYSSLKLMKSLIGNNSLICPSHDYHNE 619 Query: 470 TATSVAEEKKYNPRLTKSLAEFVEI 544 T + E K N L + + ++I Sbjct: 620 FTTCLETEMKRNSLLRQVINSEIDI 644 >UniRef50_A6LR94 Cluster: Beta-lactamase domain protein; n=1; Clostridium beijerinckii NCIMB 8052|Rep: Beta-lactamase domain protein - Clostridium beijerinckii NCIMB 8052 Length = 224 Score = 51.2 bits (117), Expect = 2e-05 Identities = 25/84 (29%), Positives = 41/84 (48%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394 D D + G ++ TPGHT G + + + FTGDT+ IRGCG + G+ ++ Sbjct: 102 DSDKISIGKLKMDCVLTPGHTAGGMCFKLENK--LFTGDTIFIRGCGICTCKGGDYNEMF 159 Query: 395 KSVHNRIFTLPDEYVLYPAHDYRG 466 +S+ ++YP H + G Sbjct: 160 ESIKKIKEIAKKNVLIYPGHYFEG 183 >UniRef50_A0YF48 Cluster: Hydroxyacylglutathione hydrolase; n=2; unclassified Gammaproteobacteria (miscellaneous)|Rep: Hydroxyacylglutathione hydrolase - marine gamma proteobacterium HTCC2143 Length = 258 Score = 51.2 bits (117), Expect = 2e-05 Identities = 30/88 (34%), Positives = 46/88 (52%), Gaps = 4/88 (4%) Frame = +2 Query: 209 LLDGDLVRFGSH-ELLAAATPGHTNGCLTYICHEQSL---AFTGDTLLIRGCGRTDFQEG 376 L G+L+ + +L TPGHT L ++ EQ + FTGDTL G G + G Sbjct: 92 LTAGELIDLDTGVQLRVLDTPGHTYAHLCFLVLEQGIEVAVFTGDTLFNAGVGHC--RSG 149 Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDY 460 + ++LY+++ + L D +YP HDY Sbjct: 150 DVDSLYQTIAEQFHCLDDNVRVYPGHDY 177 >UniRef50_Q4QBB0 Cluster: Metallo-beta-lactamase family protein-like protein; n=3; Leishmania|Rep: Metallo-beta-lactamase family protein-like protein - Leishmania major Length = 380 Score = 51.2 bits (117), Expect = 2e-05 Identities = 35/101 (34%), Positives = 49/101 (48%), Gaps = 1/101 (0%) Frame = +2 Query: 233 FGSHELLAAA-TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHN 409 FG H +L TPGH+ G + + L FTGD L G GR D G+ E L +S+ Sbjct: 268 FGPHSVLHYVFTPGHSPGHMMLALPRERLLFTGDVLFYNGVGRVDLPWGSGERLAESLLT 327 Query: 410 RIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAE 532 + PD VL P H T++ E++ N R ++L E Sbjct: 328 -LEGYPDNTVLLPGHG----RLTTLGRERREN-RALRALYE 362 >UniRef50_A5V0A4 Cluster: Beta-lactamase domain protein; n=2; Roseiflexus|Rep: Beta-lactamase domain protein - Roseiflexus sp. RS-1 Length = 489 Score = 50.8 bits (116), Expect = 2e-05 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 19/129 (14%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYI------CHEQSLAFTGDTLLIRGCGRTDFQE- 373 DGD +R G+ + A TPGHT + Y E + TGD+L I RTD Sbjct: 102 DGDEIRIGNIIIRAIHTPGHTPEHMAYAVIDTPRASEPWMVLTGDSLFINDVARTDLVNL 161 Query: 374 --GNSETLYKSVHNRIFTLPDEYVLYPAH---------DYRGQTATSVAEEKKYNPRL-T 517 E +Y S+ R+ LPD +YPAH G+ +++ E+++N L Sbjct: 162 PLAGPEVIYTSI-QRLLELPDYCEIYPAHYGGSACGGKQMSGKPVSTIGFERRFNWMLQA 220 Query: 518 KSLAEFVEI 544 + + EF+ + Sbjct: 221 RDVHEFISL 229 >UniRef50_A7RVP5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 318 Score = 50.8 bits (116), Expect = 2e-05 Identities = 34/116 (29%), Positives = 54/116 (46%), Gaps = 5/116 (4%) Frame = +2 Query: 254 AAATPGHTNGCLTYICH-----EQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIF 418 A +TPGHT G + Y+ H F+GD L + GCGR EG + +S+ + Sbjct: 160 AFSTPGHTAGHVVYLLHGAVFNSVDSLFSGDLLFLGGCGR--IFEGAPGEMLESLQT-VS 216 Query: 419 TLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNLNLPYPKMINK 586 +L D+ +L+P HDY + + N L + VE+ +N + P I + Sbjct: 217 SLKDDTLLWPGHDYAMKNLMFALTIEPSNYHLRAKMDWVVEMRNNKYMTSPSTIGE 272 >UniRef50_Q2BJ10 Cluster: Metallo-beta-lactamase superfamily protein; n=1; Neptuniibacter caesariensis|Rep: Metallo-beta-lactamase superfamily protein - Neptuniibacter caesariensis Length = 257 Score = 49.6 bits (113), Expect(2) = 3e-05 Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 2/86 (2%) Frame = +2 Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYIC--HEQSLAFTGDTLLIRGCGRTDFQEGNS 382 L DGD ++ + A PGHT ++Y H+ L F GDTL + GCGR EG + Sbjct: 90 LNDGDSIQLMGASVAIKAIPGHTLDHISYYSERHKPQL-FCGDTLFLAGCGR--LFEGTA 146 Query: 383 ETLYKSVHNRIFTLPDEYVLYPAHDY 460 + + ++ N +LPD+ +Y H+Y Sbjct: 147 KQMLNAM-NYFASLPDDTEVYCTHEY 171 Score = 20.6 bits (41), Expect(2) = 3e-05 Identities = 8/11 (72%), Positives = 9/11 (81%) Frame = +2 Query: 476 TSVAEEKKYNP 508 TS+AEEK NP Sbjct: 209 TSIAEEKLINP 219 >UniRef50_Q3WFW5 Cluster: Beta-lactamase-like; n=1; Frankia sp. EAN1pec|Rep: Beta-lactamase-like - Frankia sp. EAN1pec Length = 346 Score = 50.4 bits (115), Expect = 3e-05 Identities = 31/94 (32%), Positives = 48/94 (51%), Gaps = 3/94 (3%) Frame = +2 Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDF 367 G +AD+ LLDG V L+A TPGHT G L + E+ L FTGD +L + Sbjct: 160 GIEADVELLDGAAVPGTGGALVAIHTPGHTTGHLCFHDRERGLVFTGDHVLPKVTPNVAL 219 Query: 368 QEGN-SETLYKSVHNRIF--TLPDEYVLYPAHDY 460 + G+ ++ L + + + LPD + P H++ Sbjct: 220 RPGSAADPLLAFLDSLRYLRDLPDNLLALPGHEW 253 >UniRef50_A6VVZ9 Cluster: Hydroxyacylglutathione hydrolase; n=2; Marinomonas|Rep: Hydroxyacylglutathione hydrolase - Marinomonas sp. MWYL1 Length = 257 Score = 50.4 bits (115), Expect = 3e-05 Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 1/83 (1%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQS-LAFTGDTLLIRGCGRTDFQEGNSETL 391 DGD + S ATPGHT L Y +++ + +GDTL GCGR EG E + Sbjct: 90 DGDRILVFSKVFTVIATPGHTLDHLCYFSEQETPILLSGDTLFKGGCGR--IMEGTHEQM 147 Query: 392 YKSVHNRIFTLPDEYVLYPAHDY 460 ++ +I LP++ ++Y H+Y Sbjct: 148 LAAM-IKISGLPNDTLIYGTHEY 169 >UniRef50_A3UF19 Cluster: Metallo-beta-lactamase family protein; n=4; Alphaproteobacteria|Rep: Metallo-beta-lactamase family protein - Oceanicaulis alexandrii HTCC2633 Length = 255 Score = 50.4 bits (115), Expect = 3e-05 Identities = 30/81 (37%), Positives = 40/81 (49%) Frame = +2 Query: 218 GDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYK 397 GD V G+ GHT G + Y E +AF GD+L GCGR EG + + Sbjct: 96 GDAVALGNLTARVMDVGGHTLGHVAYWFEEAGVAFVGDSLFALGCGR--MFEGTPQQMQA 153 Query: 398 SVHNRIFTLPDEYVLYPAHDY 460 + R+ LP E V+Y AH+Y Sbjct: 154 GL-ARLRGLPPETVIYCAHEY 173 >UniRef50_P95849 Cluster: Orf c06001 protein; n=2; Sulfolobus|Rep: Orf c06001 protein - Sulfolobus solfataricus Length = 247 Score = 50.4 bits (115), Expect = 3e-05 Identities = 38/139 (27%), Positives = 67/139 (48%), Gaps = 19/139 (13%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQS---------LAFTGDTLLIRGCGRTDF 367 +G+ ++ G+ ++ TPGHT ++ + +++ TGDTL + G GR D Sbjct: 96 NGEEIKAGNVKIKVLHTPGHTPDSISVLIYDRRRDESWNEPWAILTGDTLFVGGLGRIDI 155 Query: 368 -QEGNSETLYKSVHNRIFTLPDEYVLYPAH--------DYRGQTATSVAEEKKYNPRL-T 517 E E LY S+ ++ LPD +YPAH G+ ++++ EK++N Sbjct: 156 GGENAEENLYYSL-AKLKELPDYVEIYPAHTAGSVCGIGISGKPSSTIGFEKRFNSLFRI 214 Query: 518 KSLAEFVEIMDNLNLPYPK 574 + EFV + + +P PK Sbjct: 215 NNKDEFVNRIREVKMPKPK 233 >UniRef50_A4C5I6 Cluster: Putative hydroxyacylglutathione hydrolase with metallo- hydrolase/oxidoreductase domain; n=4; Proteobacteria|Rep: Putative hydroxyacylglutathione hydrolase with metallo- hydrolase/oxidoreductase domain - Pseudoalteromonas tunicata D2 Length = 261 Score = 50.0 bits (114), Expect = 4e-05 Identities = 26/67 (38%), Positives = 39/67 (58%) Frame = +2 Query: 260 ATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYV 439 ATPGHT + Y +Q F GDTL GCGR EG ++ +++S+ ++ LPD+ Sbjct: 112 ATPGHTLDHICYYEPQQDWLFCGDTLFSGGCGR--LFEGTADQMFQSM-VKLSQLPDKTA 168 Query: 440 LYPAHDY 460 +Y H+Y Sbjct: 169 VYCTHEY 175 >UniRef50_A4BIQ3 Cluster: Hydroxyacylglutathione hydrolase; n=1; Reinekea sp. MED297|Rep: Hydroxyacylglutathione hydrolase - Reinekea sp. MED297 Length = 258 Score = 50.0 bits (114), Expect = 4e-05 Identities = 33/94 (35%), Positives = 44/94 (46%), Gaps = 5/94 (5%) Frame = +2 Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLA-----FTGDTLLIRGCGR 358 ++DI L DG VR G L TPGHT G ++ + L+ DTL G G Sbjct: 87 ESDIWLEDGQEVRLGKETLTHYLTPGHTPGHGVFLYQDPQLSERDFLVCADTLFNAGVGN 146 Query: 359 TDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460 T + GN LY++V L + L+P HDY Sbjct: 147 T--RSGNVSELYQTVDRLKSLLRPQTRLFPGHDY 178 >UniRef50_A0NAW9 Cluster: ENSANGP00000031703; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000031703 - Anopheles gambiae str. PEST Length = 144 Score = 50.0 bits (114), Expect = 4e-05 Identities = 24/82 (29%), Positives = 40/82 (48%) Frame = +2 Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSET 388 L +GD ++ G TPGH+ G +TY + +GD L GRTD + N + Sbjct: 63 LNEGDELKLGDDVFHIYFTPGHSPGSITYHNPDGKFIISGDVLFEGSIGRTDLFKANFDQ 122 Query: 389 LYKSVHNRIFTLPDEYVLYPAH 454 L S+ ++ LP++ ++ H Sbjct: 123 LIDSIKTKLLILPEDTQVFSGH 144 >UniRef50_Q6MFA0 Cluster: Putative uncharacterized protein; n=1; Candidatus Protochlamydia amoebophila UWE25|Rep: Putative uncharacterized protein - Protochlamydia amoebophila (strain UWE25) Length = 210 Score = 49.6 bits (113), Expect = 6e-05 Identities = 27/87 (31%), Positives = 42/87 (48%) Frame = +2 Query: 194 QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQE 373 +A+I L DGDL+ G TPGH+ G + + QS +GDTL G F Sbjct: 105 KANIFLNDGDLIPVGQLTFKVIHTPGHSPGSVCFYEISQSKLLSGDTLFKGSIGNISFPT 164 Query: 374 GNSETLYKSVHNRIFTLPDEYVLYPAH 454 + ++ S+ +++ LP +YP H Sbjct: 165 SQPDLMWTSL-DKLAQLPPSTSVYPGH 190 >UniRef50_A6EE42 Cluster: Rhodanese-like protein; n=1; Pedobacter sp. BAL39|Rep: Rhodanese-like protein - Pedobacter sp. BAL39 Length = 459 Score = 49.6 bits (113), Expect = 6e-05 Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 13/93 (13%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQS---LAFTGDTLLIRGCGRTDFQE--GN 379 +G + G +L + TPGH+ + I + FTGDTL I CGR D +E GN Sbjct: 93 EGAEIVLGELKLKSIHTPGHSPDSICIILEQNGNDKAVFTGDTLFIGDCGRPDLRESVGN 152 Query: 380 --------SETLYKSVHNRIFTLPDEYVLYPAH 454 + +Y S+ ++ L DE ++YPAH Sbjct: 153 LTAKRDELAAQMYYSLREKLMALEDEVLVYPAH 185 >UniRef50_A4IWV0 Cluster: Metallo-beta-lactamase superfamily protein; n=11; Francisella tularensis|Rep: Metallo-beta-lactamase superfamily protein - Francisella tularensis subsp. tularensis (strain WY96-3418) Length = 252 Score = 49.6 bits (113), Expect = 6e-05 Identities = 26/87 (29%), Positives = 40/87 (45%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 DI++ DG + G PGH + + ++ ++ F GDTL G G + + Sbjct: 87 DIYVKDGSFINLGFTSFRVMYIPGHIDDHVCFLFEQERALFCGDTLFNAGVGGVQAESAD 146 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDY 460 LY S+ +I L + YPAHDY Sbjct: 147 INQLYDSL-VKITKLDGDIKPYPAHDY 172 >UniRef50_A3Q4D8 Cluster: Beta-lactamase domain protein; n=8; Actinomycetales|Rep: Beta-lactamase domain protein - Mycobacterium sp. (strain JLS) Length = 453 Score = 49.6 bits (113), Expect = 6e-05 Identities = 37/126 (29%), Positives = 58/126 (46%), Gaps = 17/126 (13%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQS----LAFTGDTLLIRGCGRTDF----- 367 +GD++ G L TPGHT+ ++Y+ + + FTG ++L GRTD Sbjct: 91 EGDVIDAGPIRLEVLHTPGHTHHHVSYVLSDDTGTVHGVFTGGSMLFGTTGRTDLVGPDD 150 Query: 368 QEGNSETLYKSVHNRIFTLPDEYVLYPAHDY--------RGQTATSVAEEKKYNPRLTKS 523 E + Y SV LP + V+YP H + A+++ E+ + NP LTK Sbjct: 151 TEKLTHAQYHSVRKIADRLPADTVVYPTHGFGSFCSATPASGDASTIGEQWQANPALTKD 210 Query: 524 LAEFVE 541 FV+ Sbjct: 211 EQSFVD 216 >UniRef50_A2BQ40 Cluster: Putative hydroxyacylglutathione hydrolase; n=2; Prochlorococcus marinus|Rep: Putative hydroxyacylglutathione hydrolase - Prochlorococcus marinus (strain AS9601) Length = 303 Score = 49.6 bits (113), Expect = 6e-05 Identities = 33/130 (25%), Positives = 60/130 (46%), Gaps = 1/130 (0%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICH-EQSLAFTGDTLLIRGCGRTDFQEG 376 ++ + DG+ + E+ GHT+ + + + E + F GDTL GCGR EG Sbjct: 150 NVSVEDGETLNILGEEVKIIEVLGHTSSHIAFFLNGENPVLFIGDTLFSGGCGR--IFEG 207 Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNL 556 + +Y S+ RI +LP ++Y AH+Y K + + L+E + + Sbjct: 208 TYQQMYSSL-ERIKSLPKNTLIYCAHEYTKANILWALNLKPKDQDIKNKLSEVEKKLSLN 266 Query: 557 NLPYPKMINK 586 L P ++++ Sbjct: 267 ELTIPFLLDE 276 >UniRef50_A0LJP1 Cluster: Beta-lactamase domain protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Beta-lactamase domain protein - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 209 Score = 49.6 bits (113), Expect = 6e-05 Identities = 29/81 (35%), Positives = 43/81 (53%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D L +G+L G +L TPGH+ G ++ E+ + FTGD + G GRTD GN Sbjct: 103 DFFLAEGELDVKGL-KLEIIHTPGHSPGSVSIYWRERKVLFTGDVIFKEGLGRTDLPGGN 161 Query: 380 SETLYKSVHNRIFTLPDEYVL 442 E L +S+ R+ E++L Sbjct: 162 GELLKRSI-KRLSEFDAEWML 181 >UniRef50_A0LFL1 Cluster: Beta-lactamase domain protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Beta-lactamase domain protein - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 617 Score = 49.6 bits (113), Expect = 6e-05 Identities = 37/102 (36%), Positives = 50/102 (49%), Gaps = 12/102 (11%) Frame = +2 Query: 185 SGAQADIH-LLDGDLVRFGSHELLAAATPGHT-NGCLTYICHE----QSLAFTGDTLLIR 346 SGA+ I L +G + G+ + A TPGHT +G + E + FTGDTL + Sbjct: 77 SGAKYKIEPLKEGSTFKVGAAMVKAVETPGHTPDGMCGLVFSEGDDQPKMIFTGDTLFVG 136 Query: 347 GCGRTDFQEG--NSETL----YKSVHNRIFTLPDEYVLYPAH 454 GR D EG + TL Y + HN + LPD + PAH Sbjct: 137 SVGRPDLLEGKMTAATLASMSYDTWHNVLSKLPDTVAVLPAH 178 >UniRef50_Q7VR07 Cluster: Zn-dependent hydrolase; n=7; Gammaproteobacteria|Rep: Zn-dependent hydrolase - Blochmannia floridanus Length = 211 Score = 49.2 bits (112), Expect = 7e-05 Identities = 25/85 (29%), Positives = 38/85 (44%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D L DGD ++ G + PGH+ G + Q GD L + GR+D G+ Sbjct: 110 DFWLKDGDQIQVGYEKFNVLHCPGHSPGHVVLWNKLQKFIIMGDVLFKKHIGRSDLPGGD 169 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAH 454 L S+ ++ +L D+ V P H Sbjct: 170 YTVLMHSIRTKLLSLSDDIVFLPGH 194 >UniRef50_Q1Q513 Cluster: Putative uncharacterized protein; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Putative uncharacterized protein - Candidatus Kuenenia stuttgartiensis Length = 461 Score = 49.2 bits (112), Expect = 7e-05 Identities = 39/130 (30%), Positives = 60/130 (46%), Gaps = 21/130 (16%) Frame = +2 Query: 209 LLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLA-------FTGDTLLIRGCGRTDF 367 L +GD + G+ L TPGHT ++ + + S + TGD L + GR D Sbjct: 91 LKEGDTIELGTAILEVLHTPGHTPHSISLLVKDTSRSEEEPWFMLTGDLLFVGDVGRPDL 150 Query: 368 Q-----EGNSETLYKSVHNRIFTLPDEYVLYPAH--------DYRGQTATSVAEEKKYNP 508 E + LY+S++ ++ LPD +YPAH +T+T++ E+ NP Sbjct: 151 AGKELLEKQVKNLYESIYKKLGKLPDRLGVYPAHGQGSLCGKGISSKTSTTLGYERHANP 210 Query: 509 RL-TKSLAEF 535 L SL EF Sbjct: 211 LLRLDSLDEF 220 >UniRef50_Q0RV10 Cluster: Possible hydroxyacylglutathione hydrolase; n=2; Actinomycetales|Rep: Possible hydroxyacylglutathione hydrolase - Rhodococcus sp. (strain RHA1) Length = 381 Score = 49.2 bits (112), Expect = 7e-05 Identities = 32/87 (36%), Positives = 42/87 (48%), Gaps = 5/87 (5%) Frame = +2 Query: 209 LLDGDLVRFGSHELLAAAT--PGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNS 382 L DGD + GS + A PGHT G + E L GDT+ +RG GR D Sbjct: 209 LKDGDQLDLGSAVVRAMTMHLPGHTPGTTALLVSETVL-LVGDTVFVRGLGRPDLTGQAD 267 Query: 383 E---TLYKSVHNRIFTLPDEYVLYPAH 454 E L++SVH R+ L ++ PAH Sbjct: 268 ELARDLFRSVHERLRPLDPRTIIAPAH 294 >UniRef50_A1U0V1 Cluster: Hydroxyacylglutathione hydrolase; n=3; Marinobacter|Rep: Hydroxyacylglutathione hydrolase - Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 / VT8)(Marinobacter hydrocarbonoclasticus (strain DSM 11845)) Length = 263 Score = 49.2 bits (112), Expect = 7e-05 Identities = 39/120 (32%), Positives = 58/120 (48%), Gaps = 4/120 (3%) Frame = +2 Query: 188 GAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYIC----HEQSLAFTGDTLLIRGCG 355 GA +H GD V + A PGHT + Y +++ + F GDTL + GCG Sbjct: 85 GATNTVHA--GDEVVWEGITFNVLAVPGHTLDHIAYYSDTQVNDKPVLFCGDTLFVCGCG 142 Query: 356 RTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEF 535 R EG E ++ S+ + LPD +Y AH+Y T ++ + + P K+LAEF Sbjct: 143 R--LFEGTPEQMHTSLQT-LRDLPDNTAVYCAHEY---TLANLRFARHWLPE-DKALAEF 195 >UniRef50_A1RAH8 Cluster: Metallo-beta-lactamase superfamily protein; n=2; Micrococcineae|Rep: Metallo-beta-lactamase superfamily protein - Arthrobacter aurescens (strain TC1) Length = 216 Score = 49.2 bits (112), Expect = 7e-05 Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 7/116 (6%) Frame = +2 Query: 128 ALGKLKSLVPGTKSVIGKDSGA---QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYI 298 AL +L ++ + S D+ A D+ L GD+ +F E+ A GHT G + ++ Sbjct: 80 ALPELVAVTGASTSAGADDADALPVPVDVRLGHGDVEQFDGFEVTAVHLRGHTPGSIAFV 139 Query: 299 CHE---QSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIF-TLPDEYVLYPAH 454 + + F+GD+L G G T +L V R+F PDE +++P H Sbjct: 140 YQDPDGPAHIFSGDSLFPGGVGNTQNDPSRFTSLLNDVSERLFDAYPDETLVHPGH 195 >UniRef50_A0L873 Cluster: Hydroxyacylglutathione hydrolase; n=1; Magnetococcus sp. MC-1|Rep: Hydroxyacylglutathione hydrolase - Magnetococcus sp. (strain MC-1) Length = 254 Score = 47.6 bits (108), Expect(2) = 8e-05 Identities = 32/87 (36%), Positives = 43/87 (49%) Frame = +2 Query: 200 DIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGN 379 D L G G H++ TPGHT+G L Y H F GDTL GCGR EG Sbjct: 91 DEALRGGQTFCLGPHQVDTYHTPGHTSGHLCY--HIADCLFAGDTLFSYGCGR--LFEGT 146 Query: 380 SETLYKSVHNRIFTLPDEYVLYPAHDY 460 + +++S+ + LP+ L AH+Y Sbjct: 147 PQQMWQSL-LILRALPETTRLCCAHEY 172 Score = 21.0 bits (42), Expect(2) = 8e-05 Identities = 8/11 (72%), Positives = 10/11 (90%) Frame = +2 Query: 482 VAEEKKYNPRL 514 +AEEK+YNP L Sbjct: 212 LAEEKQYNPFL 222 >UniRef50_Q125G3 Cluster: Beta-lactamase-like precursor; n=7; Bacteria|Rep: Beta-lactamase-like precursor - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 251 Score = 48.8 bits (111), Expect = 1e-04 Identities = 35/137 (25%), Positives = 61/137 (44%), Gaps = 17/137 (12%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICH------EQSLAFTGDTLLIRGCGRTDFQEG 376 DG + G+ + TPGHT + + E TGDTL + GR D Sbjct: 95 DGQRLEAGNVVVDILHTPGHTPDSICLLVRDLRRGDEPWFVITGDTLFVGAAGRPDLAGR 154 Query: 377 NSET---LYKSVHNRIFTLPDEYVLYPAHD--------YRGQTATSVAEEKKYNPRLTKS 523 E L+ ++H ++ TLP + ++P H G+ ++++ E+++NP L+ S Sbjct: 155 EREMAGQLHDTLHAKLLTLPADLEIFPGHQAGSACGVGLSGKPSSTIGFERRFNPMLSMS 214 Query: 524 LAEFVEIMDNLNLPYPK 574 FV+ + P P+ Sbjct: 215 REAFVKALTADIPPQPQ 231 >UniRef50_Q0LHZ1 Cluster: Beta-lactamase-like; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Beta-lactamase-like - Herpetosiphon aurantiacus ATCC 23779 Length = 369 Score = 48.8 bits (111), Expect = 1e-04 Identities = 41/144 (28%), Positives = 67/144 (46%), Gaps = 18/144 (12%) Frame = +2 Query: 227 VRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQ------EGNSET 388 ++ G+ + A ATPGHT ++Y+ + S F+GDTL + GR D + + + Sbjct: 212 IQLGAATIQALATPGHTWESMSYLL-DGSHLFSGDTLFLAAVGRPDLEAQAAEAQQRASA 270 Query: 389 LYKSVHNRIFTLPDEYVLYPAHDYRG------QTATSVAEEKKYNPRLTKSLAEFVEIMD 550 LY+S+ I L ++ P H + S+AE + PRL ++ AEFV + Sbjct: 271 LYQSLQT-ILALDPASIILPGHTSKPVAFDGVPIMASLAEVQTATPRLAQTEAEFVAGLT 329 Query: 551 NLNLPYPK------MINKAGAGEP 604 + P +N+AGA P Sbjct: 330 AVRPATPPNHQTIVQLNQAGAALP 353 >UniRef50_Q4UGN4 Cluster: Hydroxyacylglutathione hydrolase, putative; n=2; Theileria|Rep: Hydroxyacylglutathione hydrolase, putative - Theileria annulata Length = 362 Score = 48.8 bits (111), Expect = 1e-04 Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 8/115 (6%) Frame = +2 Query: 140 LKSLVPGTKSVIGKDSGAQADIHL--LDGDLVRFGSHELLAAATPGHTNGCLTYIC---- 301 +K LVP + V+G + L + FG+ + HT G + Y Sbjct: 175 IKKLVPDVE-VVGSSYEETPGVTLPVKHEQTLTFGNLVIKCLKASCHTLGHIMYYVYHPS 233 Query: 302 --HEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460 H+Q L F+GDTL I GCGR F EG++ ++ + V + +LP+ +LY H+Y Sbjct: 234 NDHQQPLLFSGDTLFISGCGR--FFEGDARSMMEIVET-VKSLPENTLLYCGHEY 285 >UniRef50_P57336 Cluster: Probable hydroxyacylglutathione hydrolase; n=2; Buchnera aphidicola|Rep: Probable hydroxyacylglutathione hydrolase - Buchnera aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon pisumsymbiotic bacterium) Length = 251 Score = 48.8 bits (111), Expect = 1e-04 Identities = 28/66 (42%), Positives = 41/66 (62%) Frame = +2 Query: 263 TPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVL 442 TPGHT+G ++Y + Q F GDTL GCGR F+ + E +Y+S+ I +LPD +L Sbjct: 107 TPGHTSGHVSY--YSQPYIFCGDTLFSAGCGRV-FKNKHLE-MYRSI-KIISSLPDSTLL 161 Query: 443 YPAHDY 460 +H+Y Sbjct: 162 CCSHEY 167 >UniRef50_Q5HUY3 Cluster: Metallo-beta-lactamase family protein; n=6; Epsilonproteobacteria|Rep: Metallo-beta-lactamase family protein - Campylobacter jejuni (strain RM1221) Length = 198 Score = 48.4 bits (110), Expect = 1e-04 Identities = 29/106 (27%), Positives = 55/106 (51%) Frame = +2 Query: 191 AQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQ 370 ++A+ + D +++ G + PGHT GC +++ F+GD L R GR DF Sbjct: 92 SKANYLIDDENIISIGGLDFKFHFLPGHTPGCTMIEIVGKNIMFSGDFLFYRSIGRWDFP 151 Query: 371 EGNSETLYKSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNP 508 ++ + +S+ ++ T +++ L P H GQ T++ EE+ + P Sbjct: 152 YSDANLMKQSL-EKVMTYKEDFKLLPGH---GQ-ETTLKEEQVHLP 192 >UniRef50_A1SJB6 Cluster: Beta-lactamase domain protein; n=13; Actinomycetales|Rep: Beta-lactamase domain protein - Nocardioides sp. (strain BAA-499 / JS614) Length = 237 Score = 48.4 bits (110), Expect = 1e-04 Identities = 27/83 (32%), Positives = 42/83 (50%) Frame = +2 Query: 266 PGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLY 445 PG T G + F+GD L GRTD G+ +T+ +S+ +++ L D+ V+ Sbjct: 151 PGGTRGAEPSGSDVSEVMFSGDLLFAGSIGRTDLPGGDHQTMLQSLKSKVLPLADDVVVL 210 Query: 446 PAHDYRGQTATSVAEEKKYNPRL 514 P H G+ TS+ E+ NP L Sbjct: 211 PGH---GE-QTSIGRERATNPYL 229 >UniRef50_Q0W7P0 Cluster: Putative uncharacterized protein; n=1; uncultured methanogenic archaeon RC-I|Rep: Putative uncharacterized protein - Uncultured methanogenic archaeon RC-I Length = 208 Score = 48.4 bits (110), Expect = 1e-04 Identities = 37/107 (34%), Positives = 48/107 (44%), Gaps = 2/107 (1%) Frame = +2 Query: 140 LKSLVPGTKSVIGKDSGA-QADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSL 316 +KS + G DS + D+ L DGD + G +L TPGHT G + Sbjct: 80 IKSSKINCARMFGSDSPELKVDMVLKDGDEIDLGDVKLRVIHTPGHTPGSICLYEPVSKA 139 Query: 317 AFTGDTLLIR-GCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAH 454 FTGDT+ G GRTD GN E + S+ T + LYP H Sbjct: 140 MFTGDTVFEEGGFGRTDI-GGNPEHMLSSL--ATLTRFEVVTLYPGH 183 >UniRef50_P72933 Cluster: Probable hydroxyacylglutathione hydrolase; n=13; Bacteria|Rep: Probable hydroxyacylglutathione hydrolase - Synechocystis sp. (strain PCC 6803) Length = 257 Score = 48.4 bits (110), Expect = 1e-04 Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 5/91 (5%) Frame = +2 Query: 203 IHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQS-----LAFTGDTLLIRGCGRTDF 367 + L DGD + F E PGHT G + Y S F GDT+ GCGR Sbjct: 90 VFLRDGDRLSFADREATVYFVPGHTRGHIAYYFAPGSGETIGDLFCGDTIFAGGCGR--L 147 Query: 368 QEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460 EG + +S+ ++ LPD+ L+ AH+Y Sbjct: 148 FEGTPAQMVQSI-GKLRQLPDQTRLWCAHEY 177 >UniRef50_Q7VQB7 Cluster: Probable hydroxyacylglutathione hydrolase; n=2; Candidatus Blochmannia|Rep: Probable hydroxyacylglutathione hydrolase - Blochmannia floridanus Length = 256 Score = 48.0 bits (109), Expect = 2e-04 Identities = 28/88 (31%), Positives = 48/88 (54%) Frame = +2 Query: 197 ADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEG 376 A I + +GD ++ + E+ PGHT + + + +S F+GDT+ GCG Q G Sbjct: 86 ATITVSEGDTLQILNQEIKVLNFPGHTPHHIGF--YYKSWLFSGDTIFSAGCG--TIQTG 141 Query: 377 NSETLYKSVHNRIFTLPDEYVLYPAHDY 460 ++ +YKS+ +I LP ++Y H+Y Sbjct: 142 YTQAMYKSL-LKIQCLPKNTLIYSGHEY 168 >UniRef50_Q2LPQ6 Cluster: Hydroxyacylglutathione hydrolase; n=2; Deltaproteobacteria|Rep: Hydroxyacylglutathione hydrolase - Syntrophus aciditrophicus (strain SB) Length = 235 Score = 48.0 bits (109), Expect = 2e-04 Identities = 29/92 (31%), Positives = 43/92 (46%) Frame = +2 Query: 260 ATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFTLPDEYV 439 ATPGHT + + H ++ TGDTL G G+ + Y S+ +I TLP E V Sbjct: 98 ATPGHTRDSICF--HTDTILLTGDTLFNGTVGNCF--SGDIHSFYSSIR-KILTLPPETV 152 Query: 440 LYPAHDYRGQTATSVAEEKKYNPRLTKSLAEF 535 +Y HDY + + NP + L+ + Sbjct: 153 IYAGHDYVRDSLAMARHLEPDNPAIDDFLSVY 184 >UniRef50_A0UWD4 Cluster: Beta-lactamase-like; n=1; Clostridium cellulolyticum H10|Rep: Beta-lactamase-like - Clostridium cellulolyticum H10 Length = 235 Score = 48.0 bits (109), Expect = 2e-04 Identities = 26/97 (26%), Positives = 49/97 (50%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394 DG++++ G ++ TPGHT G + + + SL FTGDT+ + GCG G++ ++ Sbjct: 114 DGEVIKLGYTDIKCILTPGHTMGGMCFFV-DGSL-FTGDTIFMEGCGICSNLGGDAGDMF 171 Query: 395 KSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYN 505 S++ + + +Y H Q ++ + K N Sbjct: 172 HSINRIKAEVSHDTKMYSGHTIDRQPGCTLGDLIKNN 208 >UniRef50_A0DY50 Cluster: Chromosome undetermined scaffold_7, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_7, whole genome shotgun sequence - Paramecium tetraurelia Length = 489 Score = 48.0 bits (109), Expect = 2e-04 Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 11/91 (12%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHE----QSLAFTGDTLLIRGCGRTDFQEGNS 382 D + ++ G ++ A TPGHT ++ ++ Q +TGDTL + GR D + Sbjct: 136 DNEFLKVGKVKIQALHTPGHTQESTCFLLYDEEGKQHSIYTGDTLFLGEVGRPDLAVKSD 195 Query: 383 ET-------LYKSVHNRIFTLPDEYVLYPAH 454 T LY S+ +I LPD+ +++P H Sbjct: 196 VTQYDLASLLYASLKQKILGLPDDVIVFPGH 226 >UniRef50_Q5AXZ0 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 659 Score = 48.0 bits (109), Expect = 2e-04 Identities = 35/123 (28%), Positives = 58/123 (47%), Gaps = 18/123 (14%) Frame = +2 Query: 218 GDLVRFGSH-ELLAAATPGHTNGCLTYICH--EQSLAFTGDTLLI--------------R 346 G++ + G + A TP HT + Y EQ FTGDTL I Sbjct: 477 GEVFKIGDRISVTALHTPCHTQDSICYFMQDGEQKAVFTGDTLFIGGMTEWINAESSAAA 536 Query: 347 GCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY-RGQTATSVAEEKKYNPRLTKS 523 GCGR F EG + ++K+++ + +LP++ +YP H+Y +G +A + + ++ Sbjct: 537 GCGR--FFEGTAPEMHKALNETLASLPEDTKVYPGHEYTKGNVKFCLAVSQSEPVKKLQA 594 Query: 524 LAE 532 AE Sbjct: 595 FAE 597 >UniRef50_Q2H306 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 256 Score = 48.0 bits (109), Expect = 2e-04 Identities = 35/103 (33%), Positives = 53/103 (51%), Gaps = 13/103 (12%) Frame = +2 Query: 320 FTGDTLLIR--GCGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY-------RGQT 472 F GD++ G R DF GN+ LY++ ++FTLP Y +Y HDY Q Sbjct: 126 FCGDSIFNSDVGSARCDFPGGNANDLYQTA-TKLFTLPPAYKIYTGHDYPPKTPRATPQA 184 Query: 473 ATSVAEEKKYNPRLT--KSLAEFV--EIMDNLNLPYPKMINKA 589 A++VAE+ +N L S A+FV + L P++I++A Sbjct: 185 ASTVAEQMAHNKHLKAGTSQADFVSWRTERDAGLAEPRLIHQA 227 >UniRef50_A5DYF9 Cluster: Hydroxyacylglutathione hydrolase; n=2; Saccharomycetaceae|Rep: Hydroxyacylglutathione hydrolase - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 282 Score = 48.0 bits (109), Expect = 2e-04 Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 4/73 (5%) Frame = +2 Query: 254 AAATPGHTNGCLTYICHE----QSLAFTGDTLLIRGCGRTDFQEGNSETLYKSVHNRIFT 421 A TP HT + Y + + FTGDTL I GCGR F EG + +++ + Sbjct: 136 ALHTPCHTQDSICYYVKDAKTGEKAVFTGDTLFISGCGR--FFEGTGAEMNVALNKILAK 193 Query: 422 LPDEYVLYPAHDY 460 LP + +YP H+Y Sbjct: 194 LPKDTKVYPGHEY 206 >UniRef50_UPI0000E23FD0 Cluster: PREDICTED: hydroxyacylglutathione hydrolase-like isoform 2; n=1; Pan troglodytes|Rep: PREDICTED: hydroxyacylglutathione hydrolase-like isoform 2 - Pan troglodytes Length = 285 Score = 47.6 bits (108), Expect = 2e-04 Identities = 26/82 (31%), Positives = 45/82 (54%), Gaps = 5/82 (6%) Frame = +2 Query: 230 RFGSHELLAAATPGHTNGCLTYI-----CHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394 +FG+ + TPGHT G ++Y C + F+GD L + GCG EG+++ +Y Sbjct: 91 QFGAIHVRCLLTPGHTGGHMSYFLWEDDCPDPPALFSGDALSVAGCG--SCLEGSAQQMY 148 Query: 395 KSVHNRIFTLPDEYVLYPAHDY 460 +S+ + TLP E ++ H++ Sbjct: 149 QSL-AEMGTLPPETKVFCGHEH 169 >UniRef50_A6FY39 Cluster: Probable hydroxyacylglutathione hydrolase; n=1; Plesiocystis pacifica SIR-1|Rep: Probable hydroxyacylglutathione hydrolase - Plesiocystis pacifica SIR-1 Length = 270 Score = 47.6 bits (108), Expect = 2e-04 Identities = 38/130 (29%), Positives = 56/130 (43%) Frame = +2 Query: 215 DGDLVRFGSHELLAAATPGHTNGCLTYICHEQSLAFTGDTLLIRGCGRTDFQEGNSETLY 394 +GD+VR G+ E T GH +G ++Y E L F GDTL GCG +G + T++ Sbjct: 95 EGDVVRLGALEGQVMLTEGHIDGHVSYRFGE--LLFCGDTLFAGGCGY--LFDGPAATMH 150 Query: 395 KSVHNRIFTLPDEYVLYPAHDYRGQTATSVAEEKKYNPRLTKSLAEFVEIMDNLNLPYPK 574 S+ R+ LP+ + AH+Y + N L + + E I P Sbjct: 151 ASL-QRLAGLPESTKVVCAHEYTQDNLRFAWSVEPDNAALAERIREVWAIRARGESTVPS 209 Query: 575 MINKAGAGEP 604 I A P Sbjct: 210 TIGLERATNP 219 >UniRef50_A4AQV7 Cluster: Metallo-beta-lactamase superfamily protein; n=17; Bacteroidetes|Rep: Metallo-beta-lactamase superfamily protein - Flavobacteriales bacterium HTCC2170 Length = 492 Score = 47.6 bits (108), Expect = 2e-04 Identities = 43/161 (26%), Positives = 68/161 (42%), Gaps = 25/161 (15%) Frame = +2 Query: 158 GTKSVIGKDSGAQADIHLL-DGDLVRFGSHELLAAATPGHTNGCLTYIC----HEQSLAF 322 G + V G + D + D + G +++ TPGHT TY+ +Q Sbjct: 92 GAQIVFGPTANPNYDALIAEDNQIFELGDYKIKVLHTPGHTMESTTYLLIDENDKQHGII 151 Query: 323 TGDTLLIRGCGRTDF---------QEGNSETLYKSVHNRIFTLPDEYVLYPAHD------ 457 TGDTL I GR D +E + L+ S+ N+I L D+ ++YP H Sbjct: 152 TGDTLFIGDVGRPDLAQHVVSELTEEKLAGHLFDSLRNKIMPLDDKLIVYPNHGAGSACG 211 Query: 458 --YRGQTATSVAEEKKYNPRLTKSLA--EFV-EIMDNLNLP 565 +T ++ +KK N L + EF+ E++ L P Sbjct: 212 KMMSKETTDTLGHQKKVNYALRADMTKDEFIKELLTGLTAP 252 >UniRef50_A1WFG7 Cluster: Hydroxyacylglutathione hydrolase precursor; n=4; Proteobacteria|Rep: Hydroxyacylglutathione hydrolase precursor - Verminephrobacter eiseniae (strain EF01-2) Length = 258 Score = 47.6 bits (108), Expect = 2e-04 Identities = 32/97 (32%), Positives = 45/97 (46%), Gaps = 3/97 (3%) Frame = +2 Query: 179 KDSGAQADIHLLDGDLVRFGSHELLAAATPGHTNGCLTYICHEQS---LAFTGDTLLIRG 349 ++S + + L GD V L PGHT G + Y C + L F GDTL G Sbjct: 77 RESVPEPLVRLAQGDTVDVLGLRLEVIDVPGHTAGHIAYYCPQMDGAPLLFCGDTLFSGG 136 Query: 350 CGRTDFQEGNSETLYKSVHNRIFTLPDEYVLYPAHDY 460 CGR EG + S+ +R+ LP ++ AH+Y Sbjct: 137 CGR--LFEGTPAQMLASL-DRLAALPGNTLVCCAHEY 170 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 636,683,416 Number of Sequences: 1657284 Number of extensions: 13417060 Number of successful extensions: 43010 Number of sequences better than 10.0: 460 Number of HSP's better than 10.0 without gapping: 40997 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 42773 length of database: 575,637,011 effective HSP length: 97 effective length of database: 414,880,463 effective search space used: 42732687689 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
- SilkBase 1999-2023 -