Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30063
(640 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q02218 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 97 2e-19
UniRef50_A6SI56 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11
UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 65 2e-09
UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1; ... 64 4e-09
UniRef50_Q4SL15 Cluster: Chromosome 17 SCAF14563, whole genome s... 63 6e-09
UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albica... 63 6e-09
UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole gen... 54 2e-06
UniRef50_UPI00015B6161 Cluster: PREDICTED: hypothetical protein;... 53 7e-06
UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5; Viridipla... 53 7e-06
UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1... 51 2e-05
UniRef50_Q2UQN4 Cluster: RIB40 genomic DNA, SC005; n=1; Aspergil... 47 3e-04
UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 46 8e-04
UniRef50_Q74B13 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 45 0.001
UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, who... 45 0.001
UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 44 0.004
UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 43 0.007
UniRef50_Q4Q171 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 42 0.017
UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 41 0.022
UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 41 0.022
UniRef50_Q9PD29 Cluster: Oxoglutarate dehydrogenase; n=17; Bacte... 41 0.029
UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 40 0.038
UniRef50_UPI000051A0C7 Cluster: PREDICTED: similar to CG33791-PC... 38 0.15
UniRef50_Q23KH1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 38 0.20
UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 38 0.27
UniRef50_Q1CZK3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 37 0.36
UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase (Succinyl-tr... 37 0.36
UniRef50_A7CWX7 Cluster: Oxoglutarate dehydrogenase; n=1; Opitut... 37 0.36
UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 37 0.36
UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 37 0.36
UniRef50_Q46181 Cluster: Beta-toxin; n=3; Clostridium perfringen... 36 0.82
UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1;... 36 0.82
UniRef50_A2VCT3 Cluster: OGDH protein; n=22; Bilateria|Rep: OGDH... 35 1.4
UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 35 1.4
UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 34 2.5
UniRef50_A7HVL7 Cluster: Putative uncharacterized protein; n=2; ... 34 3.3
UniRef50_Q4P2J5 Cluster: Putative uncharacterized protein; n=1; ... 34 3.3
UniRef50_UPI0000DD7C6C Cluster: PREDICTED: hypothetical protein;... 33 4.4
UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 33 4.4
UniRef50_UPI00006A27F8 Cluster: UPI00006A27F8 related cluster; n... 33 5.8
UniRef50_Q5RHG8 Cluster: Carbamoyl-phosphate synthetase 2, aspar... 33 5.8
UniRef50_Q0YMH5 Cluster: Geobacter sulfurreducens, CxxxxCH...CXX... 33 5.8
UniRef50_UPI0000E4A4F7 Cluster: PREDICTED: similar to MAGI-1; n=... 33 7.7
UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 33 7.7
UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1;... 33 7.7
UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 33 7.7
UniRef50_A7AU90 Cluster: Putative uncharacterized protein; n=1; ... 33 7.7
UniRef50_A5DZM2 Cluster: Putative uncharacterized protein; n=1; ... 33 7.7
>UniRef50_Q02218 Cluster: 2-oxoglutarate dehydrogenase E1 component,
mitochondrial precursor; n=77; Eumetazoa|Rep:
2-oxoglutarate dehydrogenase E1 component, mitochondrial
precursor - Homo sapiens (Human)
Length = 1002
Score = 97.5 bits (232), Expect = 2e-19
Identities = 61/144 (42%), Positives = 80/144 (55%), Gaps = 2/144 (1%)
Frame = +2
Query: 191 SERFASWLLNKPQTAAVSVNANRLKSSP-AAEPFLNGSSSAYVETMYNAWLADPNSVHAS 367
S+ ++ N+P AA + R S+P AAEPFL+G+SS YVE MY AWL +P SVH S
Sbjct: 17 SQTVKTFSQNRP-AAARTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKS 75
Query: 368 WDAFFRNATNGAQPGAAYTPPPNLAPYNKNXVP-LTSLVXXXXXXXXXXXXXXXNEKIID 544
WD FFRN GA PG AY P L+ + V SLV +K+++
Sbjct: 76 WDIFFRNTNAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNV----------DKLVE 125
Query: 545 DHLAVXAIIXSYQARGHPGGRCGP 616
DHLAV ++I +YQ RGH + P
Sbjct: 126 DHLAVQSLIRAYQIRGHHVAQLDP 149
>UniRef50_A6SI56 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 334
Score = 70.9 bits (166), Expect = 2e-11
Identities = 45/142 (31%), Positives = 69/142 (48%), Gaps = 2/142 (1%)
Frame = +2
Query: 176 SKSG-QSERFASWLLNKPQTAAVSVNANRLKSSPAAEPFLNGSSSAYVETMYNAWLADPN 352
SKS S+R + ++++ + + + +A L S FL+G+++ Y++ MY W DP+
Sbjct: 33 SKSALSSKRRSLAIISQKRHESTTASATDLNDS-----FLSGNTANYIDEMYMQWKEDPS 87
Query: 353 SVHASWDAFFRNATNGAQP-GAAYTPPPNLAPYNKNXVPLTSLVXXXXXXXXXXXXXXXN 529
SVH SW +FRN +G P A+TPPP L P VP
Sbjct: 88 SVHISWQVYFRNMESGDMPMSQAFTPPPTLVPTPTGGVP-----------SFLPGLGGAE 136
Query: 530 EKIIDDHLAVXAIIXSYQARGH 595
+ +HL V + +YQARGH
Sbjct: 137 GSEVTNHLKVQLLCRAYQARGH 158
>UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 component,
mitochondrial precursor; n=34; Fungi/Metazoa group|Rep:
2-oxoglutarate dehydrogenase E1 component, mitochondrial
precursor - Saccharomyces cerevisiae (Baker's yeast)
Length = 1014
Score = 64.9 bits (151), Expect = 2e-09
Identities = 35/113 (30%), Positives = 58/113 (51%), Gaps = 3/113 (2%)
Frame = +2
Query: 266 SSPAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGA-AYTPPPNLA 442
++ + FL+ S++ Y++ MY AW DP+SVH SWDA+F+N +N P A+ PP+++
Sbjct: 37 ATTGTDNFLSTSNATYIDEMYQAWQKDPSSVHVSWDAYFKNMSNPKIPATKAFQAPPSIS 96
Query: 443 --PYNKNXVPLTSLVXXXXXXXXXXXXXXXNEKIIDDHLAVXAIIXSYQARGH 595
P PL + + ++ + HL V + +YQ RGH
Sbjct: 97 NFPQGTEAAPLGTAMTGSV------------DENVSIHLKVQLLCRAYQVRGH 137
>UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1013
Score = 63.7 bits (148), Expect = 4e-09
Identities = 35/107 (32%), Positives = 52/107 (48%), Gaps = 1/107 (0%)
Frame = +2
Query: 278 AEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNL-APYNK 454
+E FL+G+SS YVE M+ W+ DP SVH SW +FF ++ G G A+ PP L +
Sbjct: 45 SESFLDGTSSTYVEDMFANWVKDPKSVHPSWASFFESSERGVPAGEAFMSPPTLGSSVAT 104
Query: 455 NXVPLTSLVXXXXXXXXXXXXXXXNEKIIDDHLAVXAIIXSYQARGH 595
P T + K + D + + ++ +YQ RGH
Sbjct: 105 KATPST-------------YTSSGSPKQVSDSMRLLLLVRAYQVRGH 138
>UniRef50_Q4SL15 Cluster: Chromosome 17 SCAF14563, whole genome
shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 17
SCAF14563, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1054
Score = 62.9 bits (146), Expect = 6e-09
Identities = 44/128 (34%), Positives = 57/128 (44%)
Frame = +2
Query: 233 AAVSVNANRLKSSPAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPG 412
AA V+ S P S+ +YVE MY +WL DP SVH SWD FFRN
Sbjct: 38 AAGVVDRRSCSSGAVTGPSALTSNPSYVEEMYFSWLEDPKSVHKSWDMFFRNMEASPSGE 97
Query: 413 AAYTPPPNLAPYNKNXVPLTSLVXXXXXXXXXXXXXXXNEKIIDDHLAVXAIIXSYQARG 592
AA P L + +S V +K+++DHLAV +I +YQ RG
Sbjct: 98 AADRRPSTL--LRGRTLSHSSDVA---------------QKVVEDHLAVHTLIRAYQTRG 140
Query: 593 HPGGRCGP 616
H + P
Sbjct: 141 HHVAQLDP 148
>UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albicans
CaKGD1 2-oxoglutarate dehydrogenase; n=4;
Ascomycota|Rep: Similar to CA3149|CaKGD1 Candida
albicans CaKGD1 2-oxoglutarate dehydrogenase -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 997
Score = 62.9 bits (146), Expect = 6e-09
Identities = 34/113 (30%), Positives = 54/113 (47%), Gaps = 1/113 (0%)
Frame = +2
Query: 281 EPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRN-ATNGAQPGAAYTPPPNLAPYNKN 457
+ FL +++ Y++ MY AW DP+SVH SW+A+F+N ++ P A+T PP + P
Sbjct: 31 DSFLLSNNANYIDEMYAAWKHDPSSVHISWNAYFKNIESSNVPPSKAFTAPPTIIP---- 86
Query: 458 XVPLTSLVXXXXXXXXXXXXXXXNEKIIDDHLAVXAIIXSYQARGHPGGRCGP 616
NE ++ HL V ++ +YQ RGH + P
Sbjct: 87 -------TVAGGAAGFVPGSSPTNEDVV-THLKVQLLVRAYQVRGHQKAKIDP 131
>UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr13 scaffold_17, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 973
Score = 54.4 bits (125), Expect = 2e-06
Identities = 31/68 (45%), Positives = 40/68 (58%), Gaps = 1/68 (1%)
Frame = +2
Query: 188 QSERFASWLL-NKPQTAAVSVNANRLKSSPAAEPFLNGSSSAYVETMYNAWLADPNSVHA 364
Q+ F S +L +K Q A V + S + FL+G+SS Y+E + AW ADPNSV
Sbjct: 38 QNRYFHSTVLKSKAQAAPVP---RPVPLSRLTDSFLDGTSSVYLEELQRAWEADPNSVDE 94
Query: 365 SWDAFFRN 388
SWD FFRN
Sbjct: 95 SWDNFFRN 102
>UniRef50_UPI00015B6161 Cluster: PREDICTED: hypothetical protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
protein - Nasonia vitripennis
Length = 1012
Score = 52.8 bits (121), Expect = 7e-06
Identities = 33/113 (29%), Positives = 48/113 (42%), Gaps = 8/113 (7%)
Frame = +2
Query: 281 EPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNX 460
+ FL +SS Y+E +++ W DP+SV SWD +FR +GA G + +
Sbjct: 31 DSFLTQTSSQYIEHLFSKWRKDPSSVPESWDVYFRKVESGAPLGPSPRKSSLKSSSKMQD 90
Query: 461 VPLTSL--------VXXXXXXXXXXXXXXXNEKIIDDHLAVXAIIXSYQARGH 595
VP L + E ++ L + A I SYQARGH
Sbjct: 91 VPANLLGAQRIEYDLMTKPRVRLKSEAEIQGEAYVESTLDINATIRSYQARGH 143
>UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5;
Viridiplantae|Rep: OSIGBa0096P03.7 protein - Oryza
sativa (Rice)
Length = 1016
Score = 52.8 bits (121), Expect = 7e-06
Identities = 26/56 (46%), Positives = 33/56 (58%)
Frame = +2
Query: 221 KPQTAAVSVNANRLKSSPAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRN 388
+PQ A V + S + FL+G+SS Y+E + AW ADP SV SWD FFRN
Sbjct: 39 RPQRFATPV-PRAVPLSRLTDSFLDGTSSVYLEELQRAWEADPTSVDESWDNFFRN 93
>UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1
component family protein; n=1; Tetrahymena thermophila
SB210|Rep: 2-oxoglutarate dehydrogenase, E1 component
family protein - Tetrahymena thermophila SB210
Length = 1054
Score = 51.2 bits (117), Expect = 2e-05
Identities = 19/52 (36%), Positives = 32/52 (61%)
Frame = +2
Query: 281 EPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPN 436
+ FL G ++ +VE ++ W DP SV SW+ +F+N G +P A++ PP+
Sbjct: 36 DSFLAGCNAEFVEGLFERWAEDPTSVGPSWNNYFKNLVRGVEPEYAFSLPPS 87
>UniRef50_Q2UQN4 Cluster: RIB40 genomic DNA, SC005; n=1; Aspergillus
oryzae|Rep: RIB40 genomic DNA, SC005 - Aspergillus
oryzae
Length = 453
Score = 47.2 bits (107), Expect = 3e-04
Identities = 20/40 (50%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Frame = +2
Query: 323 MYNAWLADPNSVHASWDAFFRNATNGAQP-GAAYTPPPNL 439
MY++W DP+SVH SW A+F N NG P A+ PP L
Sbjct: 2 MYSSWKNDPSSVHLSWQAYFHNVENGHIPMDQAFMSPPGL 41
>UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=11; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase
E1 component - Coxiella burnetii
Length = 934
Score = 46.0 bits (104), Expect = 8e-04
Identities = 17/39 (43%), Positives = 28/39 (71%)
Frame = +2
Query: 287 FLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGA 403
+L +++ Y+ET+Y +L DP+SV+ W ++FR TNGA
Sbjct: 14 YLADNNAGYIETLYENFLKDPHSVNEEWRSYFRTLTNGA 52
>UniRef50_Q74B13 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=8; Deltaproteobacteria|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Geobacter sulfurreducens
Length = 894
Score = 45.2 bits (102), Expect = 0.001
Identities = 20/52 (38%), Positives = 28/52 (53%)
Frame = +2
Query: 287 FLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLA 442
F G+ ++E+++ +W ADP SV A W AFF G +A P P LA
Sbjct: 3 FAAGADPEFIESLFQSWQADPASVSAEWRAFFTGYELGRGEPSAECPTPELA 54
>UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_5,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 1002
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/110 (25%), Positives = 43/110 (39%)
Frame = +2
Query: 287 FLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNXVP 466
FL ++ +++ + + W DPNSV A+WDA+FR + +TP P
Sbjct: 24 FLGAQNAEFLDNLLDKWSQDPNSVPATWDAYFRQVCESNK--FDFTPEPQKGQ------- 74
Query: 467 LTSLVXXXXXXXXXXXXXXXNEKIIDDHLAVXAIIXSYQARGHPGGRCGP 616
T K++ DH V +I Y+ RGH P
Sbjct: 75 -TISFQADVLLHIISKQVSGVRKLLSDHFRVRLLINKYRHRGHEKSMVDP 123
>UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=2; Proteobacteria|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Nitrosococcus oceani
(strain ATCC 19707 / NCIMB 11848)
Length = 940
Score = 43.6 bits (98), Expect = 0.004
Identities = 31/125 (24%), Positives = 53/125 (42%), Gaps = 1/125 (0%)
Frame = +2
Query: 260 LKSSPAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGA-QPGAAYTPPPN 436
+K + P LN ++++Y+E +Y +L DPN+V A W +F+ G + A P +
Sbjct: 5 VKKQASPSP-LNAANASYLEALYEKFLKDPNTVPAHWRIWFKRLQAGVPEQAAPEFPARS 63
Query: 437 LAPYNKNXVPLTSLVXXXXXXXXXXXXXXXNEKIIDDHLAVXAIIXSYQARGHPGGRCGP 616
P + P + + + +AV +I +Y+ RGH P
Sbjct: 64 PGPAVQPSAPSAVMT------------EGLTAEAAEKQIAVLQLINAYRFRGHQKANIDP 111
Query: 617 ARDYD 631
R YD
Sbjct: 112 LRIYD 116
>UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 component,
mitochondrial, putative; n=9; Plasmodium|Rep:
2-oxoglutarate dehydrogenase E1 component,
mitochondrial, putative - Plasmodium vivax
Length = 1059
Score = 42.7 bits (96), Expect = 0.007
Identities = 18/45 (40%), Positives = 23/45 (51%)
Frame = +2
Query: 293 NGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTP 427
N S +AY+E Y W D NS+H SWD +F A P + P
Sbjct: 34 NPSMAAYIEGAYRMWRQDRNSLHKSWDVYFAEMAEEAGPLGSAPP 78
>UniRef50_Q4Q171 Cluster: 2-oxoglutarate dehydrogenase E1 component,
putative; n=6; Trypanosomatidae|Rep: 2-oxoglutarate
dehydrogenase E1 component, putative - Leishmania major
Length = 979
Score = 41.5 bits (93), Expect = 0.017
Identities = 20/55 (36%), Positives = 28/55 (50%)
Frame = +2
Query: 281 EPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAP 445
+ FL+GSS+ Y++ +Y W DP SV ASW F + G A P + P
Sbjct: 20 DSFLSGSSAMYMDGLYQQWKKDPASVDASWAELFSRSDLGNYNHALLDTPICVLP 74
>UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
n=2; Anaeromyxobacter|Rep: 2-oxoglutarate dehydrogenase,
E1 subunit - Anaeromyxobacter sp. Fw109-5
Length = 940
Score = 41.1 bits (92), Expect = 0.022
Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 3/57 (5%)
Frame = +2
Query: 266 SSPAAE---PFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTP 427
SSP E P + S+ ++VE +Y WLADP++V W +F + A PG A P
Sbjct: 2 SSPETELPVPAPSASNLSFVEDLYYEWLADPSAVDERWRRYFESVP--ATPGTAKAP 56
>UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=149; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Azotobacter vinelandii
Length = 943
Score = 41.1 bits (92), Expect = 0.022
Identities = 30/109 (27%), Positives = 47/109 (43%)
Frame = +2
Query: 290 LNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNXVPL 469
L+G ++AYVE +Y +L DPN+V W +F A+ G + T P+ AP V L
Sbjct: 15 LSGGNAAYVEELYELYLHDPNAVPEEWRTYFEKLP--AEAGTS-TDVPH-APVRDQFVLL 70
Query: 470 TSLVXXXXXXXXXXXXXXXNEKIIDDHLAVXAIIXSYQARGHPGGRCGP 616
+K ++ V +I +Y+ RGH + P
Sbjct: 71 AKNQRRAQPVATSSVSTEHEKKQVE----VLRLIQAYRTRGHQASQLDP 115
>UniRef50_Q9PD29 Cluster: Oxoglutarate dehydrogenase; n=17;
Bacteria|Rep: Oxoglutarate dehydrogenase - Xylella
fastidiosa
Length = 967
Score = 40.7 bits (91), Expect = 0.029
Identities = 18/48 (37%), Positives = 28/48 (58%)
Frame = +2
Query: 239 VSVNANRLKSSPAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFF 382
+S+ N +K + P L G ++AY+E +Y +L PNSV W A+F
Sbjct: 23 LSIVDNLIKQFTQSSP-LAGGNAAYIEDLYEQYLVSPNSVDPKWKAYF 69
>UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=15; Bacteria|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Deinococcus radiodurans
Length = 956
Score = 40.3 bits (90), Expect = 0.038
Identities = 15/37 (40%), Positives = 25/37 (67%)
Frame = +2
Query: 296 GSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQ 406
G ++A++E +Y ++L DP+SV A W ++F GAQ
Sbjct: 15 GGNAAFIEGLYESYLQDPSSVGAEWRSYFDGLRGGAQ 51
>UniRef50_UPI000051A0C7 Cluster: PREDICTED: similar to CG33791-PC,
isoform C; n=1; Apis mellifera|Rep: PREDICTED: similar
to CG33791-PC, isoform C - Apis mellifera
Length = 980
Score = 38.3 bits (85), Expect = 0.15
Identities = 26/102 (25%), Positives = 42/102 (41%), Gaps = 4/102 (3%)
Frame = +2
Query: 302 SSAYVETMYNAWLADPNSVHASWDAFFR---NATNGAQPGAAYTPPPNLAPYNKNXVPLT 472
S Y+E MY +W DP+SV SW+ +F+ ++ + + P + + P +
Sbjct: 3 SIQYLEYMYQSWKKDPSSVSDSWNRYFKLIDEKDKKSEAASHKSSPKSTSSSTHGGSPSS 62
Query: 473 -SLVXXXXXXXXXXXXXXXNEKIIDDHLAVXAIIXSYQARGH 595
S +K I + A I +YQARGH
Sbjct: 63 QSTKSPEQNAKSKSNSDMQGDKYIIGAFDINATIRAYQARGH 104
>UniRef50_Q23KH1 Cluster: 2-oxoglutarate dehydrogenase, E1 component
family protein; n=1; Tetrahymena thermophila SB210|Rep:
2-oxoglutarate dehydrogenase, E1 component family
protein - Tetrahymena thermophila SB210
Length = 992
Score = 37.9 bits (84), Expect = 0.20
Identities = 14/27 (51%), Positives = 18/27 (66%)
Frame = +2
Query: 302 SSAYVETMYNAWLADPNSVHASWDAFF 382
S+ YVE M++ W DPNSVH W +F
Sbjct: 37 SNLYVEQMFDQWSKDPNSVHEMWRDYF 63
>UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=4; Leptospira|Rep: 2-oxoglutarate dehydrogenase E1
component - Leptospira interrogans
Length = 920
Score = 37.5 bits (83), Expect = 0.27
Identities = 16/46 (34%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Frame = +2
Query: 290 LNGSSSAYVETMYNAWLADPNSVHASWDAFFRNA-TNGAQPGAAYT 424
L G + A +E +YN + +P ++ W +FF+ TNG G+ YT
Sbjct: 9 LYGENGALLEELYNQYKLNPETLDKEWKSFFQEVDTNGLANGSGYT 54
>UniRef50_Q1CZK3 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=2; Cystobacterineae|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Myxococcus xanthus (strain
DK 1622)
Length = 963
Score = 37.1 bits (82), Expect = 0.36
Identities = 15/43 (34%), Positives = 25/43 (58%)
Frame = +2
Query: 281 EPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQP 409
+ FL+G++ ++E +Y +L DP SV ASW F + +P
Sbjct: 6 DTFLSGANIDFIEGLYARYLEDPASVDASWREVFDRSNGAGRP 48
>UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase
(Succinyl-transferring), E1 component; n=4;
Bacteroidetes|Rep: Oxoglutarate dehydrogenase
(Succinyl-transferring), E1 component - Cytophaga
hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 946
Score = 37.1 bits (82), Expect = 0.36
Identities = 15/43 (34%), Positives = 26/43 (60%)
Frame = +2
Query: 254 NRLKSSPAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFF 382
NR KS+ +++ + +YV+ MY ++ DP+SV +W FF
Sbjct: 5 NRKKSTMDNYSYVSNAEISYVDEMYQSYRKDPSSVDETWQKFF 47
>UniRef50_A7CWX7 Cluster: Oxoglutarate dehydrogenase; n=1;
Opitutaceae bacterium TAV2|Rep: Oxoglutarate
dehydrogenase - Opitutaceae bacterium TAV2
Length = 384
Score = 37.1 bits (82), Expect = 0.36
Identities = 18/43 (41%), Positives = 27/43 (62%), Gaps = 3/43 (6%)
Frame = +2
Query: 299 SSSAYVETMYNAWLADPNSVHASWDAFFRN---ATNGAQPGAA 418
++SA +E Y+ WL +P+SV +W AFF+ T G+ GAA
Sbjct: 9 ANSAILEQTYSQWLDNPDSVDPTWRAFFQGFTLGTTGSPIGAA 51
>UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=16; cellular organisms|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Robiginitalea biformata
HTCC2501
Length = 940
Score = 37.1 bits (82), Expect = 0.36
Identities = 15/40 (37%), Positives = 24/40 (60%)
Frame = +2
Query: 287 FLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQ 406
FLN + +A+ +Y+ +L P+SV SW AFF+ G +
Sbjct: 6 FLNAAHTAFFSDLYDRYLTHPDSVEPSWRAFFQGFDFGME 45
>UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=70; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase
E1 component - Haemophilus influenzae
Length = 935
Score = 37.1 bits (82), Expect = 0.36
Identities = 16/50 (32%), Positives = 26/50 (52%)
Frame = +2
Query: 278 AEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTP 427
A L G++ +Y+E +Y ++L+DP SV SW F + +TP
Sbjct: 12 ASTALGGANQSYIEELYESYLSDPQSVEESWRKTFDSLPKTTALEQPHTP 61
>UniRef50_Q46181 Cluster: Beta-toxin; n=3; Clostridium
perfringens|Rep: Beta-toxin - Clostridium perfringens
Length = 336
Score = 35.9 bits (79), Expect = 0.82
Identities = 22/87 (25%), Positives = 42/87 (48%)
Frame = +2
Query: 140 TIMHRARIVFNISKSGQSERFASWLLNKPQTAAVSVNANRLKSSPAAEPFLNGSSSAYVE 319
+I +IV +I K+ S++ S + ++ + N+ K+S +E + S+ YV+
Sbjct: 134 SINENVKIVDSIPKNTISQKTVSNTMGYKIGGSIEIEKNKPKASIESE-YAESSTIEYVQ 192
Query: 320 TMYNAWLADPNSVHASWDAFFRNATNG 400
++ D ++ ASWD F T G
Sbjct: 193 PDFSTIQTDHSTSKASWDTKFTETTRG 219
>UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Alpha-ketoglutarate
decarboxylase - Lentisphaera araneosa HTCC2155
Length = 913
Score = 35.9 bits (79), Expect = 0.82
Identities = 14/31 (45%), Positives = 20/31 (64%)
Frame = +2
Query: 293 NGSSSAYVETMYNAWLADPNSVHASWDAFFR 385
+ ++ AY+E M + DPNSV ASW FF+
Sbjct: 8 DNANPAYIEMMLQKFKTDPNSVDASWQQFFQ 38
>UniRef50_A2VCT3 Cluster: OGDH protein; n=22; Bilateria|Rep: OGDH
protein - Homo sapiens (Human)
Length = 640
Score = 35.1 bits (77), Expect = 1.4
Identities = 13/29 (44%), Positives = 21/29 (72%)
Frame = +2
Query: 530 EKIIDDHLAVXAIIXSYQARGHPGGRCGP 616
+K+++DHLAV ++I +YQ RGH + P
Sbjct: 12 DKLVEDHLAVQSLIRAYQIRGHHVAQLDP 40
>UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=97; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Brucella melitensis
Length = 1004
Score = 35.1 bits (77), Expect = 1.4
Identities = 16/43 (37%), Positives = 22/43 (51%)
Frame = +2
Query: 275 AAEPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGA 403
A FL G ++ Y+E +Y + DPNSV W FF + A
Sbjct: 16 ALTSFLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNA 58
>UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=12; root|Rep: 2-oxoglutarate dehydrogenase,
E1 component - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 963
Score = 34.3 bits (75), Expect = 2.5
Identities = 14/32 (43%), Positives = 21/32 (65%)
Frame = +2
Query: 287 FLNGSSSAYVETMYNAWLADPNSVHASWDAFF 382
+L G ++ YVE MY +LA+P SV +W +F
Sbjct: 20 YLFGGNAPYVEEMYENYLANPGSVPDNWRDYF 51
>UniRef50_A7HVL7 Cluster: Putative uncharacterized protein; n=2;
Rhizobiales|Rep: Putative uncharacterized protein -
Parvibaculum lavamentivorans DS-1
Length = 299
Score = 33.9 bits (74), Expect = 3.3
Identities = 25/84 (29%), Positives = 37/84 (44%)
Frame = +2
Query: 197 RFASWLLNKPQTAAVSVNANRLKSSPAAEPFLNGSSSAYVETMYNAWLADPNSVHASWDA 376
RFA W+ P A + R+ P+A FLN + + ++ +Y + D N +H A
Sbjct: 108 RFAEWIRQLPVPWAAEFSGQRVTLDPSA-VFLNFNYTPSLQRLYG--VPDINVLHIHGAA 164
Query: 377 FFRNATNGAQPGAAYTPPPNLAPY 448
N T G + P PN PY
Sbjct: 165 --ANPTETLVLGHGWEPDPNPDPY 186
>UniRef50_Q4P2J5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1774
Score = 33.9 bits (74), Expect = 3.3
Identities = 28/92 (30%), Positives = 40/92 (43%)
Frame = +2
Query: 164 VFNISKSGQSERFASWLLNKPQTAAVSVNANRLKSSPAAEPFLNGSSSAYVETMYNAWLA 343
+FN S G++ ++ P AVS N SP + P + SS W+
Sbjct: 163 LFNSSTVGRARAYSP--TKDPYDRAVSPTKNLSYDSPLSSPKKDDSS----------WIQ 210
Query: 344 DPNSVHASWDAFFRNATNGAQPGAAYTPPPNL 439
P S +F+ NA+NGA PG+ T P L
Sbjct: 211 SP-STPKQHGSFWSNASNGAYPGSNATGPSQL 241
>UniRef50_UPI0000DD7C6C Cluster: PREDICTED: hypothetical protein;
n=1; Homo sapiens|Rep: PREDICTED: hypothetical protein -
Homo sapiens
Length = 241
Score = 33.5 bits (73), Expect = 4.4
Identities = 13/24 (54%), Positives = 16/24 (66%)
Frame = +2
Query: 359 HASWDAFFRNATNGAQPGAAYTPP 430
HA W AFFR +++ PG A TPP
Sbjct: 47 HAGWTAFFRGSSSVRVPGPASTPP 70
>UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=14; Rickettsia|Rep: 2-oxoglutarate dehydrogenase E1
component - Rickettsia felis (Rickettsia azadi)
Length = 977
Score = 33.5 bits (73), Expect = 4.4
Identities = 12/32 (37%), Positives = 21/32 (65%)
Frame = +2
Query: 287 FLNGSSSAYVETMYNAWLADPNSVHASWDAFF 382
+L G ++ +V+ +Y +LA+P SV +W FF
Sbjct: 10 YLFGGNAVFVDELYRQYLANPASVDQTWQEFF 41
>UniRef50_UPI00006A27F8 Cluster: UPI00006A27F8 related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A27F8 UniRef100 entry -
Xenopus tropicalis
Length = 272
Score = 33.1 bits (72), Expect = 5.8
Identities = 13/30 (43%), Positives = 18/30 (60%)
Frame = +3
Query: 270 PPRRNPSSMAPVQLTSRPCTMHGSPTQTPY 359
PP+R P + P +RP H SPT+TP+
Sbjct: 78 PPQRQPDTPHPHSSPTRPPPRHSSPTRTPH 107
>UniRef50_Q5RHG8 Cluster: Carbamoyl-phosphate synthetase 2,
aspartate transcarbamylase, and dihydroorotase; n=23;
Coelomata|Rep: Carbamoyl-phosphate synthetase 2,
aspartate transcarbamylase, and dihydroorotase - Danio
rerio (Zebrafish) (Brachydanio rerio)
Length = 2154
Score = 33.1 bits (72), Expect = 5.8
Identities = 12/46 (26%), Positives = 21/46 (45%)
Frame = +2
Query: 296 GSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPPP 433
G+S Y+ + + + DP ++ WD F NA + G + P
Sbjct: 288 GTSRCYITSQNHGFAVDPETLPKDWDVLFTNANDQTSEGIVHNHKP 333
>UniRef50_Q0YMH5 Cluster: Geobacter sulfurreducens, CxxxxCH...CXXCH
motif precursor; n=2; Geobacter|Rep: Geobacter
sulfurreducens, CxxxxCH...CXXCH motif precursor -
Geobacter sp. FRC-32
Length = 1440
Score = 33.1 bits (72), Expect = 5.8
Identities = 27/100 (27%), Positives = 40/100 (40%)
Frame = +2
Query: 176 SKSGQSERFASWLLNKPQTAAVSVNANRLKSSPAAEPFLNGSSSAYVETMYNAWLADPNS 355
S S + R AS N T SV N ++ A + +G T A L +
Sbjct: 260 SSSNRGYRIASGTAN---TTIASVVTNYPAANKCANVYCHGGGVKVGSTQVKAPLTGGTN 316
Query: 356 VHASWDAFFRNATNGAQPGAAYTPPPNLAPYNKNXVPLTS 475
WD+ +NA G+ G PP + + K+ VP+ S
Sbjct: 317 TIPKWDSSSQNAC-GSCHGINAASPPTMGSHMKHVVPVWS 355
>UniRef50_UPI0000E4A4F7 Cluster: PREDICTED: similar to MAGI-1; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
MAGI-1 - Strongylocentrotus purpuratus
Length = 1040
Score = 32.7 bits (71), Expect = 7.7
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 4/59 (6%)
Frame = +3
Query: 270 PPRRNPSSMAPVQLTSRPCTMHGSPTQTPYT----RLGMHFSAMRQTELSQAPHTRRRP 434
PP P+++ P + + H S PYT R G SA R T LS+ PH + P
Sbjct: 564 PPDYIPNNLGPTGDDAASRSSHNSSRDYPYTPPNQRRGHGPSARRDTNLSRMPHVKSLP 622
>UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=3; Bacteria|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Salinibacter ruber (strain
DSM 13855)
Length = 1243
Score = 32.7 bits (71), Expect = 7.7
Identities = 15/44 (34%), Positives = 24/44 (54%)
Frame = +2
Query: 296 GSSSAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTP 427
G ++ Y+E +Y + DP+SV SW FF + P A++ P
Sbjct: 5 GFNTGYIEELYKQYQDDPDSVSESWREFFAD----YDPDASFIP 44
>UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
Plesiocystis pacifica SIR-1|Rep: Alpha-ketoglutarate
decarboxylase - Plesiocystis pacifica SIR-1
Length = 927
Score = 32.7 bits (71), Expect = 7.7
Identities = 14/31 (45%), Positives = 20/31 (64%)
Frame = +2
Query: 278 AEPFLNGSSSAYVETMYNAWLADPNSVHASW 370
AE L+ + A++E +Y A+ ADPNSV W
Sbjct: 3 AEAALSVHNLAFLEALYEAYEADPNSVDPQW 33
>UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=1; Orientia tsutsugamushi Boryong|Rep:
2-oxoglutarate dehydrogenase, E1 component - Orientia
tsutsugamushi (strain Boryong) (Rickettsia
tsutsugamushi)
Length = 963
Score = 32.7 bits (71), Expect = 7.7
Identities = 12/35 (34%), Positives = 22/35 (62%)
Frame = +2
Query: 281 EPFLNGSSSAYVETMYNAWLADPNSVHASWDAFFR 385
+ FL ++ Y+E ++ +L DP S+ +SW FF+
Sbjct: 9 QSFLFRQNAEYIEHLHQKYLKDPASIDSSWITFFQ 43
>UniRef50_A7AU90 Cluster: Putative uncharacterized protein; n=1;
Babesia bovis|Rep: Putative uncharacterized protein -
Babesia bovis
Length = 750
Score = 32.7 bits (71), Expect = 7.7
Identities = 16/55 (29%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
Frame = +3
Query: 279 RNPSSMAPVQLTSRPCTMHGSPTQTPYTRLGMHFSAMRQTE--LSQAPHTRRRPI 437
++ + +PV+ +S PCT++ P+ +G M Q + ++ APH RR I
Sbjct: 301 KSVEATSPVERSSDPCTIYAVPSMEDLDDMGATSDQMSQIKELITSAPHVRRAGI 355
>UniRef50_A5DZM2 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 807
Score = 32.7 bits (71), Expect = 7.7
Identities = 25/86 (29%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
Frame = +2
Query: 224 PQTAAVSVNANRLKSSPAAEPFLNGSSSAYVETMYNAWLADPNSVHASWD---AFFRNAT 394
PQT+ + NA + S +PF+ S + T + A A+ NS + FF + +
Sbjct: 653 PQTSQGAQNALASQGSQVPQPFIPQSQVPFQATQF-ATPANTNSFNGPGYYPIPFFYHPS 711
Query: 395 NGAQPGAAYTPPPNLAPYNKNXVPLT 472
A Y PPP L P++ P T
Sbjct: 712 ASGIAYATYQPPPALLPHHAYPAPPT 737
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 632,847,638
Number of Sequences: 1657284
Number of extensions: 12367185
Number of successful extensions: 36451
Number of sequences better than 10.0: 47
Number of HSP's better than 10.0 without gapping: 34969
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 36436
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 47711253245
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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