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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= maV30063
         (640 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

D32064-1|BAA06836.1| 1002|Homo sapiens 2-oxoglutarate dehydrogen...    97   4e-20
D10523-1|BAA01393.1| 1002|Homo sapiens 2-oxoglutarate dehydrogen...    97   4e-20
BC014617-1|AAH14617.1| 1023|Homo sapiens oxoglutarate (alpha-ket...    97   4e-20
BC009580-1|AAH09580.1|  427|Homo sapiens oxoglutarate (alpha-ket...    97   4e-20
BC004964-1|AAH04964.1| 1023|Homo sapiens oxoglutarate (alpha-ket...    97   4e-20
AC004859-2|AAQ96884.1|  427|Homo sapiens unknown protein.              97   4e-20
AC004859-1|AAQ96885.1| 1023|Homo sapiens unknown protein.              97   4e-20
BC026320-1|AAH26320.1| 1010|Homo sapiens oxoglutarate dehydrogen...    74   4e-13
AB033116-1|BAA86604.2| 1011|Homo sapiens KIAA1290 protein protein.     74   4e-13
AK001713-1|BAA91855.1| 1010|Homo sapiens protein ( Homo sapiens ...    74   5e-13
BC128549-1|AAI28550.1|  636|Homo sapiens OGDH protein protein.         36   0.16 
BC128550-1|AAI28551.1|  640|Homo sapiens OGDH protein protein.         35   0.21 

>D32064-1|BAA06836.1| 1002|Homo sapiens 2-oxoglutarate dehydrogenase
           protein.
          Length = 1002

 Score = 97.5 bits (232), Expect = 4e-20
 Identities = 61/144 (42%), Positives = 80/144 (55%), Gaps = 2/144 (1%)
 Frame = +2

Query: 191 SERFASWLLNKPQTAAVSVNANRLKSSP-AAEPFLNGSSSAYVETMYNAWLADPNSVHAS 367
           S+   ++  N+P  AA +    R  S+P AAEPFL+G+SS YVE MY AWL +P SVH S
Sbjct: 17  SQTVKTFSQNRP-AAARTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKS 75

Query: 368 WDAFFRNATNGAQPGAAYTPPPNLAPYNKNXVP-LTSLVXXXXXXXXXXXXXXXNEKIID 544
           WD FFRN   GA PG AY  P  L+  +   V    SLV                +K+++
Sbjct: 76  WDIFFRNTNAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNV----------DKLVE 125

Query: 545 DHLAVXAIIXSYQARGHPGGRCGP 616
           DHLAV ++I +YQ RGH   +  P
Sbjct: 126 DHLAVQSLIRAYQIRGHHVAQLDP 149


>D10523-1|BAA01393.1| 1002|Homo sapiens 2-oxoglutarate dehydrogenase
           precursor protein.
          Length = 1002

 Score = 97.5 bits (232), Expect = 4e-20
 Identities = 61/144 (42%), Positives = 80/144 (55%), Gaps = 2/144 (1%)
 Frame = +2

Query: 191 SERFASWLLNKPQTAAVSVNANRLKSSP-AAEPFLNGSSSAYVETMYNAWLADPNSVHAS 367
           S+   ++  N+P  AA +    R  S+P AAEPFL+G+SS YVE MY AWL +P SVH S
Sbjct: 17  SQTVKTFSQNRP-AAARTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKS 75

Query: 368 WDAFFRNATNGAQPGAAYTPPPNLAPYNKNXVP-LTSLVXXXXXXXXXXXXXXXNEKIID 544
           WD FFRN   GA PG AY  P  L+  +   V    SLV                +K+++
Sbjct: 76  WDIFFRNTNAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNV----------DKLVE 125

Query: 545 DHLAVXAIIXSYQARGHPGGRCGP 616
           DHLAV ++I +YQ RGH   +  P
Sbjct: 126 DHLAVQSLIRAYQIRGHHVAQLDP 149


>BC014617-1|AAH14617.1| 1023|Homo sapiens oxoglutarate
           (alpha-ketoglutarate) dehydrogenase (lipoamide) protein.
          Length = 1023

 Score = 97.5 bits (232), Expect = 4e-20
 Identities = 61/144 (42%), Positives = 80/144 (55%), Gaps = 2/144 (1%)
 Frame = +2

Query: 191 SERFASWLLNKPQTAAVSVNANRLKSSP-AAEPFLNGSSSAYVETMYNAWLADPNSVHAS 367
           S+   ++  N+P  AA +    R  S+P AAEPFL+G+SS YVE MY AWL +P SVH S
Sbjct: 17  SQTVKTFSQNRP-AAARTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKS 75

Query: 368 WDAFFRNATNGAQPGAAYTPPPNLAPYNKNXVP-LTSLVXXXXXXXXXXXXXXXNEKIID 544
           WD FFRN   GA PG AY  P  L+  +   V    SLV                +K+++
Sbjct: 76  WDIFFRNTNAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNV----------DKLVE 125

Query: 545 DHLAVXAIIXSYQARGHPGGRCGP 616
           DHLAV ++I +YQ RGH   +  P
Sbjct: 126 DHLAVQSLIRAYQIRGHHVAQLDP 149


>BC009580-1|AAH09580.1|  427|Homo sapiens oxoglutarate
           (alpha-ketoglutarate) dehydrogenase (lipoamide) protein.
          Length = 427

 Score = 97.5 bits (232), Expect = 4e-20
 Identities = 61/144 (42%), Positives = 80/144 (55%), Gaps = 2/144 (1%)
 Frame = +2

Query: 191 SERFASWLLNKPQTAAVSVNANRLKSSP-AAEPFLNGSSSAYVETMYNAWLADPNSVHAS 367
           S+   ++  N+P  AA +    R  S+P AAEPFL+G+SS YVE MY AWL +P SVH S
Sbjct: 17  SQTVKTFSQNRP-AAARTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKS 75

Query: 368 WDAFFRNATNGAQPGAAYTPPPNLAPYNKNXVP-LTSLVXXXXXXXXXXXXXXXNEKIID 544
           WD FFRN   GA PG AY  P  L+  +   V    SLV                +K+++
Sbjct: 76  WDIFFRNTNAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNV----------DKLVE 125

Query: 545 DHLAVXAIIXSYQARGHPGGRCGP 616
           DHLAV ++I +YQ RGH   +  P
Sbjct: 126 DHLAVQSLIRAYQIRGHHVAQLDP 149


>BC004964-1|AAH04964.1| 1023|Homo sapiens oxoglutarate
           (alpha-ketoglutarate) dehydrogenase (lipoamide) protein.
          Length = 1023

 Score = 97.5 bits (232), Expect = 4e-20
 Identities = 61/144 (42%), Positives = 80/144 (55%), Gaps = 2/144 (1%)
 Frame = +2

Query: 191 SERFASWLLNKPQTAAVSVNANRLKSSP-AAEPFLNGSSSAYVETMYNAWLADPNSVHAS 367
           S+   ++  N+P  AA +    R  S+P AAEPFL+G+SS YVE MY AWL +P SVH S
Sbjct: 17  SQTVKTFSQNRP-AAARTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKS 75

Query: 368 WDAFFRNATNGAQPGAAYTPPPNLAPYNKNXVP-LTSLVXXXXXXXXXXXXXXXNEKIID 544
           WD FFRN   GA PG AY  P  L+  +   V    SLV                +K+++
Sbjct: 76  WDIFFRNTNAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNV----------DKLVE 125

Query: 545 DHLAVXAIIXSYQARGHPGGRCGP 616
           DHLAV ++I +YQ RGH   +  P
Sbjct: 126 DHLAVQSLIRAYQIRGHHVAQLDP 149


>AC004859-2|AAQ96884.1|  427|Homo sapiens unknown protein.
          Length = 427

 Score = 97.5 bits (232), Expect = 4e-20
 Identities = 61/144 (42%), Positives = 80/144 (55%), Gaps = 2/144 (1%)
 Frame = +2

Query: 191 SERFASWLLNKPQTAAVSVNANRLKSSP-AAEPFLNGSSSAYVETMYNAWLADPNSVHAS 367
           S+   ++  N+P  AA +    R  S+P AAEPFL+G+SS YVE MY AWL +P SVH S
Sbjct: 17  SQTVKTFSQNRP-AAARTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKS 75

Query: 368 WDAFFRNATNGAQPGAAYTPPPNLAPYNKNXVP-LTSLVXXXXXXXXXXXXXXXNEKIID 544
           WD FFRN   GA PG AY  P  L+  +   V    SLV                +K+++
Sbjct: 76  WDIFFRNTNAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNV----------DKLVE 125

Query: 545 DHLAVXAIIXSYQARGHPGGRCGP 616
           DHLAV ++I +YQ RGH   +  P
Sbjct: 126 DHLAVQSLIRAYQIRGHHVAQLDP 149


>AC004859-1|AAQ96885.1| 1023|Homo sapiens unknown protein.
          Length = 1023

 Score = 97.5 bits (232), Expect = 4e-20
 Identities = 61/144 (42%), Positives = 80/144 (55%), Gaps = 2/144 (1%)
 Frame = +2

Query: 191 SERFASWLLNKPQTAAVSVNANRLKSSP-AAEPFLNGSSSAYVETMYNAWLADPNSVHAS 367
           S+   ++  N+P  AA +    R  S+P AAEPFL+G+SS YVE MY AWL +P SVH S
Sbjct: 17  SQTVKTFSQNRP-AAARTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKS 75

Query: 368 WDAFFRNATNGAQPGAAYTPPPNLAPYNKNXVP-LTSLVXXXXXXXXXXXXXXXNEKIID 544
           WD FFRN   GA PG AY  P  L+  +   V    SLV                +K+++
Sbjct: 76  WDIFFRNTNAGAPPGTAYQSPLPLSRGSLAAVAHAQSLVEAQPNV----------DKLVE 125

Query: 545 DHLAVXAIIXSYQARGHPGGRCGP 616
           DHLAV ++I +YQ RGH   +  P
Sbjct: 126 DHLAVQSLIRAYQIRGHHVAQLDP 149


>BC026320-1|AAH26320.1| 1010|Homo sapiens oxoglutarate
           dehydrogenase-like protein.
          Length = 1010

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 43/122 (35%), Positives = 63/122 (51%), Gaps = 1/122 (0%)
 Frame = +2

Query: 254 NRLKSSPAAEPFLNGSS-SAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPP 430
           +R    PA  P   G   S+Y+E MY AWL +P SVH SWD+FFR A+  A  G+A   P
Sbjct: 31  SRSSGPPATFPSSKGGGGSSYMEEMYFAWLENPQSVHKSWDSFFREASEEAFSGSAQPRP 90

Query: 431 PNLAPYNKNXVPLTSLVXXXXXXXXXXXXXXXNEKIIDDHLAVXAIIXSYQARGHPGGRC 610
           P++   +++ V   +                   K+++DHLAV ++I +YQ RGH   + 
Sbjct: 91  PSVVHESRSAVSSRT----------------KTSKLVEDHLAVQSLIRAYQIRGHHVAQL 134

Query: 611 GP 616
            P
Sbjct: 135 DP 136


>AB033116-1|BAA86604.2| 1011|Homo sapiens KIAA1290 protein protein.
          Length = 1011

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 43/122 (35%), Positives = 63/122 (51%), Gaps = 1/122 (0%)
 Frame = +2

Query: 254 NRLKSSPAAEPFLNGSS-SAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPP 430
           +R    PA  P   G   S+Y+E MY AWL +P SVH SWD+FFR A+  A  G+A   P
Sbjct: 32  SRSSGPPATFPSSKGGGGSSYMEEMYFAWLENPQSVHKSWDSFFREASEEAFSGSAQPRP 91

Query: 431 PNLAPYNKNXVPLTSLVXXXXXXXXXXXXXXXNEKIIDDHLAVXAIIXSYQARGHPGGRC 610
           P++   +++ V   +                   K+++DHLAV ++I +YQ RGH   + 
Sbjct: 92  PSVVHESRSAVSSRT----------------KTSKLVEDHLAVQSLIRAYQIRGHHVAQL 135

Query: 611 GP 616
            P
Sbjct: 136 DP 137


>AK001713-1|BAA91855.1| 1010|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10851 fis, clone NT2RP4001483, moderately
           similar to 2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT
           PRECURSOR (EC ).
          Length = 1010

 Score = 73.7 bits (173), Expect = 5e-13
 Identities = 43/122 (35%), Positives = 62/122 (50%), Gaps = 1/122 (0%)
 Frame = +2

Query: 254 NRLKSSPAAEPFLNGSS-SAYVETMYNAWLADPNSVHASWDAFFRNATNGAQPGAAYTPP 430
           +R    PA  P   G   S+Y+E MY AWL +P SVH SWD+FFR A+  A  G+A   P
Sbjct: 31  SRSSGPPATFPSSKGGGGSSYMEEMYFAWLENPQSVHKSWDSFFREASEEAFSGSAQPRP 90

Query: 431 PNLAPYNKNXVPLTSLVXXXXXXXXXXXXXXXNEKIIDDHLAVXAIIXSYQARGHPGGRC 610
           P++    ++ V   +                   K+++DHLAV ++I +YQ RGH   + 
Sbjct: 91  PSVVHEGRSAVSSRT----------------KTSKLVEDHLAVQSLIRAYQIRGHHVAQL 134

Query: 611 GP 616
            P
Sbjct: 135 DP 136


>BC128549-1|AAI28550.1|  636|Homo sapiens OGDH protein protein.
          Length = 636

 Score = 35.5 bits (78), Expect = 0.16
 Identities = 13/29 (44%), Positives = 21/29 (72%)
 Frame = +2

Query: 530 EKIIDDHLAVXAIIXSYQARGHPGGRCGP 616
           +K+++DHLAV ++I +YQ RGH   +  P
Sbjct: 12  DKLVEDHLAVQSLIRAYQVRGHHIAKLDP 40


>BC128550-1|AAI28551.1|  640|Homo sapiens OGDH protein protein.
          Length = 640

 Score = 35.1 bits (77), Expect = 0.21
 Identities = 13/29 (44%), Positives = 21/29 (72%)
 Frame = +2

Query: 530 EKIIDDHLAVXAIIXSYQARGHPGGRCGP 616
           +K+++DHLAV ++I +YQ RGH   +  P
Sbjct: 12  DKLVEDHLAVQSLIRAYQIRGHHVAQLDP 40


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,367,709
Number of Sequences: 237096
Number of extensions: 1953594
Number of successful extensions: 13184
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 12847
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 13184
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7028963750
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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