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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= maV30039
         (706 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AL583862-8|CAI14893.1|  247|Homo sapiens hydroxypyruvate isomera...   148   2e-35
AY775560-1|AAV84474.1|  229|Homo sapiens endothelial cell apopto...   146   9e-35
BC019041-1|AAH19041.1|  174|Homo sapiens HYI protein protein.          95   2e-19
BC006140-1|AAH06140.1|  217|Homo sapiens HYI protein protein.          95   2e-19
AL583862-5|CAI14890.1|  204|Homo sapiens hydroxypyruvate isomera...    95   2e-19
AF284751-1|AAG59853.1|  174|Homo sapiens HT036 protein.                95   2e-19
AF284750-1|AAG59852.1|  204|Homo sapiens HT036-ISO protein.            95   2e-19
AL583862-7|CAI14892.1|  165|Homo sapiens hydroxypyruvate isomera...    75   2e-13
AL583862-4|CAI14889.1|  180|Homo sapiens hydroxypyruvate isomera...    71   4e-12
AL583862-6|CAI14891.1|  229|Homo sapiens hydroxypyruvate isomera...    70   7e-12
BC067235-1|AAH67235.1|  250|Homo sapiens Unknown (protein for MG...    30   9.3  
AB033063-1|BAA86551.2| 1268|Homo sapiens KIAA1237 protein protein.     30   9.3  

>AL583862-8|CAI14893.1|  247|Homo sapiens hydroxypyruvate isomerase
           homolog (E. coli) protein.
          Length = 247

 Score =  148 bits (358), Expect = 2e-35
 Identities = 80/204 (39%), Positives = 124/204 (60%), Gaps = 7/204 (3%)
 Frame = +2

Query: 17  MKFCANLSFMFAEASSILERYALAKDAGFKAVESGFPFGFSLEQVRNAKQSAGLQQIAIN 196
           ++F ANLS++F E S +  R   A  +GF+AVE  +P+  + E +  A + AGL+ + IN
Sbjct: 4   LRFSANLSWLFPELSGLPARVRAAGSSGFEAVEVAWPYAETPEALARAAREAGLRLVLIN 63

Query: 197 LKTGDTTKGEVGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK----- 361
              GD  KGE+G+ +VPG++  F+  L   + YAKAL   +IH+MAG+V     +     
Sbjct: 64  TPPGDQEKGEMGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKA 123

Query: 362 HWE-TFEKNLLYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRL 535
             E  F +NL +A  VL  E++ GL+EPIN + + P+YFL    +A  I++++  PNL+L
Sbjct: 124 EMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQL 183

Query: 536 MLDIFHLQQIAGDITHNITKLLAI 607
            +DIFH Q + G++T NI + L I
Sbjct: 184 QMDIFHWQIMDGNLTGNIREFLPI 207



 Score = 30.3 bits (65), Expect = 7.0
 Identities = 12/20 (60%), Positives = 14/20 (70%)
 Frame = +1

Query: 610 LGHVQIAQVPNRNEPGHAPE 669
           +GHVQ+AQVP R EP    E
Sbjct: 208 VGHVQVAQVPGRGEPSSPGE 227


>AY775560-1|AAV84474.1|  229|Homo sapiens endothelial cell apoptosis
           protein E-CE1 protein.
          Length = 229

 Score =  146 bits (353), Expect = 9e-35
 Identities = 79/204 (38%), Positives = 123/204 (60%), Gaps = 7/204 (3%)
 Frame = +2

Query: 17  MKFCANLSFMFAEASSILERYALAKDAGFKAVESGFPFGFSLEQVRNAKQSAGLQQIAIN 196
           ++F ANLS++F E   +  R   A  +GF+AVE  +P+  + E +  A + AGL+ + IN
Sbjct: 4   LRFSANLSWLFPELPGLPARVRAAGSSGFEAVEVAWPYAETPEALARAAREAGLRLVLIN 63

Query: 197 LKTGDTTKGEVGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK----- 361
              GD  KGE+G+ +VPG++  F+  L   + YAKAL   +IH+MAG+V     +     
Sbjct: 64  TPPGDQEKGEMGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKA 123

Query: 362 HWE-TFEKNLLYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRL 535
             E  F +NL +A  VL  E++ GL+EPIN + + P+YFL    +A  I++++  PNL+L
Sbjct: 124 EMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQL 183

Query: 536 MLDIFHLQQIAGDITHNITKLLAI 607
            +DIFH Q + G++T NI + L I
Sbjct: 184 QMDIFHWQIMDGNLTGNIREFLPI 207


>BC019041-1|AAH19041.1|  174|Homo sapiens HYI protein protein.
          Length = 174

 Score = 95.1 bits (226), Expect = 2e-19
 Identities = 52/134 (38%), Positives = 82/134 (61%), Gaps = 7/134 (5%)
 Frame = +2

Query: 227 VGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK-----HWET-FEKNL 388
           +G+ +VPG++  F+  L   + YAKAL   +IH+MAG+V     +       E  F +NL
Sbjct: 1   MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60

Query: 389 LYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQI 565
            +A  VL  E++ GL+EPIN + + P+YFL    +A  I++++  PNL+L +DIFH Q +
Sbjct: 61  RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIM 120

Query: 566 AGDITHNITKLLAI 607
            G++T NI + L I
Sbjct: 121 DGNLTGNIREFLPI 134



 Score = 30.3 bits (65), Expect = 7.0
 Identities = 12/20 (60%), Positives = 14/20 (70%)
 Frame = +1

Query: 610 LGHVQIAQVPNRNEPGHAPE 669
           +GHVQ+AQVP R EP    E
Sbjct: 135 VGHVQVAQVPGRGEPSSPGE 154


>BC006140-1|AAH06140.1|  217|Homo sapiens HYI protein protein.
          Length = 217

 Score = 95.1 bits (226), Expect = 2e-19
 Identities = 52/134 (38%), Positives = 82/134 (61%), Gaps = 7/134 (5%)
 Frame = +2

Query: 227 VGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK-----HWET-FEKNL 388
           +G+ +VPG++  F+  L   + YAKAL   +IH+MAG+V     +       E  F +NL
Sbjct: 1   MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60

Query: 389 LYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQI 565
            +A  VL  E++ GL+EPIN + + P+YFL    +A  I++++  PNL+L +DIFH Q +
Sbjct: 61  RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIM 120

Query: 566 AGDITHNITKLLAI 607
            G++T NI + L I
Sbjct: 121 DGNLTGNIREFLPI 134



 Score = 30.3 bits (65), Expect = 7.0
 Identities = 12/20 (60%), Positives = 14/20 (70%)
 Frame = +1

Query: 610 LGHVQIAQVPNRNEPGHAPE 669
           +GHVQ+AQVP R EP    E
Sbjct: 135 VGHVQVAQVPGRGEPSSPGE 154


>AL583862-5|CAI14890.1|  204|Homo sapiens hydroxypyruvate isomerase
           homolog (E. coli) protein.
          Length = 204

 Score = 95.1 bits (226), Expect = 2e-19
 Identities = 52/134 (38%), Positives = 82/134 (61%), Gaps = 7/134 (5%)
 Frame = +2

Query: 227 VGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK-----HWET-FEKNL 388
           +G+ +VPG++  F+  L   + YAKAL   +IH+MAG+V     +       E  F +NL
Sbjct: 1   MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60

Query: 389 LYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQI 565
            +A  VL  E++ GL+EPIN + + P+YFL    +A  I++++  PNL+L +DIFH Q +
Sbjct: 61  RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIM 120

Query: 566 AGDITHNITKLLAI 607
            G++T NI + L I
Sbjct: 121 DGNLTGNIREFLPI 134



 Score = 30.3 bits (65), Expect = 7.0
 Identities = 12/20 (60%), Positives = 14/20 (70%)
 Frame = +1

Query: 610 LGHVQIAQVPNRNEPGHAPE 669
           +GHVQ+AQVP R EP    E
Sbjct: 135 VGHVQVAQVPGRGEPSSPGE 154


>AF284751-1|AAG59853.1|  174|Homo sapiens HT036 protein.
          Length = 174

 Score = 95.1 bits (226), Expect = 2e-19
 Identities = 52/134 (38%), Positives = 82/134 (61%), Gaps = 7/134 (5%)
 Frame = +2

Query: 227 VGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK-----HWET-FEKNL 388
           +G+ +VPG++  F+  L   + YAKAL   +IH+MAG+V     +       E  F +NL
Sbjct: 1   MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60

Query: 389 LYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQI 565
            +A  VL  E++ GL+EPIN + + P+YFL    +A  I++++  PNL+L +DIFH Q +
Sbjct: 61  RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIM 120

Query: 566 AGDITHNITKLLAI 607
            G++T NI + L I
Sbjct: 121 DGNLTGNIREFLPI 134



 Score = 30.3 bits (65), Expect = 7.0
 Identities = 12/20 (60%), Positives = 14/20 (70%)
 Frame = +1

Query: 610 LGHVQIAQVPNRNEPGHAPE 669
           +GHVQ+AQVP R EP    E
Sbjct: 135 VGHVQVAQVPGRGEPSSPGE 154


>AF284750-1|AAG59852.1|  204|Homo sapiens HT036-ISO protein.
          Length = 204

 Score = 95.1 bits (226), Expect = 2e-19
 Identities = 52/134 (38%), Positives = 82/134 (61%), Gaps = 7/134 (5%)
 Frame = +2

Query: 227 VGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK-----HWET-FEKNL 388
           +G+ +VPG++  F+  L   + YAKAL   +IH+MAG+V     +       E  F +NL
Sbjct: 1   MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60

Query: 389 LYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQI 565
            +A  VL  E++ GL+EPIN + + P+YFL    +A  I++++  PNL+L +DIFH Q +
Sbjct: 61  RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIM 120

Query: 566 AGDITHNITKLLAI 607
            G++T NI + L I
Sbjct: 121 DGNLTGNIREFLPI 134



 Score = 30.3 bits (65), Expect = 7.0
 Identities = 12/20 (60%), Positives = 14/20 (70%)
 Frame = +1

Query: 610 LGHVQIAQVPNRNEPGHAPE 669
           +GHVQ+AQVP R EP    E
Sbjct: 135 VGHVQVAQVPGRGEPSSPGE 154


>AL583862-7|CAI14892.1|  165|Homo sapiens hydroxypyruvate isomerase
           homolog (E. coli) protein.
          Length = 165

 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 47/134 (35%), Positives = 77/134 (57%), Gaps = 7/134 (5%)
 Frame = +2

Query: 227 VGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK-----HWET-FEKNL 388
           +G+ +VPG++  F+  L   +         +IH+MAG+V     +       E  F +NL
Sbjct: 1   MGLGAVPGRQAAFREGLEQAV---------RIHLMAGRVPQGADRIAVKAEMEAVFLENL 51

Query: 389 LYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQI 565
            +A  VL  E++ GL+EPIN + + P+YFL    +A  I++++  PNL+L +DIFH Q +
Sbjct: 52  RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIM 111

Query: 566 AGDITHNITKLLAI 607
            G++T NI + L I
Sbjct: 112 DGNLTGNIREFLPI 125



 Score = 30.3 bits (65), Expect = 7.0
 Identities = 12/20 (60%), Positives = 14/20 (70%)
 Frame = +1

Query: 610 LGHVQIAQVPNRNEPGHAPE 669
           +GHVQ+AQVP R EP    E
Sbjct: 126 VGHVQVAQVPGRGEPSSPGE 145


>AL583862-4|CAI14889.1|  180|Homo sapiens hydroxypyruvate isomerase
           homolog (E. coli) protein.
          Length = 180

 Score = 70.9 bits (166), Expect = 4e-12
 Identities = 41/104 (39%), Positives = 64/104 (61%), Gaps = 7/104 (6%)
 Frame = +2

Query: 317 KIHIMAGKVENPTPK-----HWET-FEKNLLYAVDVLKGENIQGLIEPIN-QYSMPKYFL 475
           +IH+MAG+V     +       E  F +NL +A  VL  E++ GL+EPIN + + P+YFL
Sbjct: 37  RIHLMAGRVPQGADRIAVKAEMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFL 96

Query: 476 SDYGRAVDIIKRIDSPNLRLMLDIFHLQQIAGDITHNITKLLAI 607
               +A  I++++  PNL+L +DIFH Q + G++T NI + L I
Sbjct: 97  DTPQQAAAILQKVGRPNLQLQMDIFHWQIMDGNLTGNIREFLPI 140



 Score = 30.3 bits (65), Expect = 7.0
 Identities = 12/20 (60%), Positives = 14/20 (70%)
 Frame = +1

Query: 610 LGHVQIAQVPNRNEPGHAPE 669
           +GHVQ+AQVP R EP    E
Sbjct: 141 VGHVQVAQVPGRGEPSSPGE 160


>AL583862-6|CAI14891.1|  229|Homo sapiens hydroxypyruvate isomerase
           homolog (E. coli) protein.
          Length = 229

 Score = 70.1 bits (164), Expect = 7e-12
 Identities = 41/103 (39%), Positives = 63/103 (61%), Gaps = 7/103 (6%)
 Frame = +2

Query: 320 IHIMAGKVENPTPK-----HWET-FEKNLLYAVDVLKGENIQGLIEPIN-QYSMPKYFLS 478
           IH+MAG+V     +       E  F +NL +A  VL  E++ GL+EPIN + + P+YFL 
Sbjct: 57  IHLMAGRVPQGADRIAVKAEMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLD 116

Query: 479 DYGRAVDIIKRIDSPNLRLMLDIFHLQQIAGDITHNITKLLAI 607
              +A  I++++  PNL+L +DIFH Q + G++T NI + L I
Sbjct: 117 TPQQAAAILQKVGRPNLQLQMDIFHWQIMDGNLTGNIREFLPI 159



 Score = 30.3 bits (65), Expect = 7.0
 Identities = 12/20 (60%), Positives = 14/20 (70%)
 Frame = +1

Query: 610 LGHVQIAQVPNRNEPGHAPE 669
           +GHVQ+AQVP R EP    E
Sbjct: 160 VGHVQVAQVPGRGEPSSPGE 179


>BC067235-1|AAH67235.1|  250|Homo sapiens Unknown (protein for
           MGC:72175) protein.
          Length = 250

 Score = 29.9 bits (64), Expect = 9.3
 Identities = 14/32 (43%), Positives = 17/32 (53%)
 Frame = +2

Query: 209 DTTKGEVGVTSVPGKEDEFKTNLNTTIEYAKA 304
           D T G + +TSVP    E  T L  T EY+ A
Sbjct: 147 DATTGLIPLTSVPTSAKEMTTKLGVTAEYSPA 178


>AB033063-1|BAA86551.2| 1268|Homo sapiens KIAA1237 protein protein.
          Length = 1268

 Score = 29.9 bits (64), Expect = 9.3
 Identities = 14/32 (43%), Positives = 17/32 (53%)
 Frame = +2

Query: 209 DTTKGEVGVTSVPGKEDEFKTNLNTTIEYAKA 304
           D T G + +TSVP    E  T L  T EY+ A
Sbjct: 796 DATTGLIPLTSVPTSAKEMTTKLGVTAEYSPA 827


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 98,139,905
Number of Sequences: 237096
Number of extensions: 2024389
Number of successful extensions: 4021
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 3800
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3999
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8175213644
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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