Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30038
(529 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial pre... 164 1e-39
UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial pre... 162 5e-39
UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazo... 146 3e-34
UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast precu... 143 3e-33
UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep... 140 2e-32
UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal precu... 135 7e-31
UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3; ... 126 3e-28
UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Re... 124 1e-27
UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida glab... 120 3e-26
UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5; Protostomia|... 118 6e-26
UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella ve... 117 1e-25
UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1; ... 117 1e-25
UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24... 111 7e-24
UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3; Le... 111 1e-23
UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|R... 106 3e-22
UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep: A... 104 1e-21
UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9; T... 102 6e-21
UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;... 100 4e-20
UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1; ... 96 4e-19
UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa ... 89 6e-17
UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces cere... 87 2e-16
UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|R... 73 5e-12
UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;... 72 7e-12
UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti... 71 2e-11
UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;... 70 3e-11
UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2... 70 3e-11
UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobu... 69 7e-11
UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5; Gammaproteob... 68 1e-10
UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o... 67 2e-10
UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate DeH... 66 4e-10
UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14; Thermoprote... 66 4e-10
UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=... 66 6e-10
UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re... 66 6e-10
UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacte... 65 8e-10
UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;... 64 1e-09
UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like prot... 64 1e-09
UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter... 62 6e-09
UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28; Bacteroidet... 62 6e-09
UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD bindi... 61 2e-08
UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate deh... 60 2e-08
UniRef50_P11386 Cluster: Malate dehydrogenase; n=6; Sulfolobacea... 60 2e-08
UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2; Euryarchaeot... 60 2e-08
UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R... 60 2e-08
UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4; Thermotog... 60 2e-08
UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate deh... 58 9e-08
UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4; Epsilonprote... 58 9e-08
UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17; Apicompl... 58 1e-07
UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4; Thermoplasma... 57 2e-07
UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2; Propionib... 57 2e-07
UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12; Bacteria... 57 2e-07
UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 57 3e-07
UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1; Ce... 56 4e-07
UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8; Lactoba... 56 4e-07
UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular or... 56 5e-07
UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1; Lept... 55 1e-06
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=... 55 1e-06
UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5; Tr... 55 1e-06
UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4; Lactobaci... 54 2e-06
UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2; Pl... 54 3e-06
UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=... 54 3e-06
UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2; Gammaproteo... 54 3e-06
UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacte... 54 3e-06
UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium ... 54 3e-06
UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11; Clostrid... 53 5e-06
UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12; Firmic... 53 5e-06
UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1; ... 52 6e-06
UniRef50_O26290 Cluster: Malate dehydrogenase; n=2; Methanobacte... 52 6e-06
UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2; ... 52 8e-06
UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3; Methanomi... 52 8e-06
UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17; Bacter... 52 8e-06
UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140; Bacteri... 51 2e-05
UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasm... 51 2e-05
UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae... 50 3e-05
UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2; Bacteria|... 50 3e-05
UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular org... 50 4e-05
UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7; Bacteria|... 49 6e-05
UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7; Halobacteria... 48 1e-04
UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2; ... 48 1e-04
UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 48 1e-04
UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula... 48 1e-04
UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;... 48 1e-04
UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4; Bacteroidale... 48 2e-04
UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;... 48 2e-04
UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia ... 47 3e-04
UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metaz... 46 4e-04
UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular org... 46 5e-04
UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to ENSANGP000... 46 7e-04
UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6; Bacteria|... 46 7e-04
UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;... 46 7e-04
UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5; Bacillace... 46 7e-04
UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 46 7e-04
UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9; Bacilli... 46 7e-04
UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5; Bacteroidale... 45 0.001
UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondr... 45 0.001
UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:... 45 0.001
UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1; Lactobaci... 44 0.002
UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium t... 44 0.002
UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibac... 44 0.002
UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridi... 44 0.002
UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomon... 44 0.002
UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6; Mollicute... 44 0.002
UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14; Bacill... 44 0.002
UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6; Acti... 44 0.003
UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1; Ther... 44 0.003
UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12; Ca... 44 0.003
UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate dehydrog... 43 0.005
UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4; Bacteria|... 43 0.005
UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic, puta... 43 0.005
UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 42 0.007
UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2; Desulfovi... 42 0.012
UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Re... 41 0.020
UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;... 40 0.027
UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13; Firmic... 40 0.027
UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4; Tr... 39 0.062
UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1; Corynebac... 38 0.11
UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizop... 38 0.11
UniRef50_Q017A7 Cluster: Chromosome 06 contig 1, DNA sequence; n... 38 0.14
UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia inte... 38 0.14
UniRef50_P83778 Cluster: Malate dehydrogenase, cytoplasmic; n=1;... 33 0.18
UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular or... 37 0.25
UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate ... 36 0.44
UniRef50_UPI0000D8BD94 Cluster: UPI0000D8BD94 related cluster; n... 36 0.58
UniRef50_UPI0001554DCB Cluster: PREDICTED: similar to Zinc finge... 36 0.76
UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;... 36 0.76
UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1; Asp... 36 0.76
UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6; Trichomonadi... 35 1.0
UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1... 35 1.3
UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 35 1.3
UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8; Chlamydiacea... 35 1.3
UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1; Clostri... 35 1.3
UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2; Phaeospha... 34 1.8
UniRef50_UPI0000DD82B5 Cluster: PREDICTED: hypothetical protein;... 34 2.3
UniRef50_Q4S3J0 Cluster: Chromosome 1 SCAF14749, whole genome sh... 33 3.1
UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6; Plasmodi... 33 3.1
UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1; ... 33 4.1
UniRef50_Q8NHM5 Cluster: JmjC domain-containing histone demethyl... 33 5.4
UniRef50_UPI0000E80D01 Cluster: PREDICTED: similar to microtubul... 32 9.4
UniRef50_UPI000023EEAF Cluster: hypothetical protein FG02077.1; ... 32 9.4
UniRef50_Q91LF0 Cluster: ORF90; n=1; Shrimp white spot syndrome ... 32 9.4
UniRef50_Q8XN38 Cluster: Probable hexosyltransferase; n=1; Clost... 32 9.4
UniRef50_Q1GZK2 Cluster: Putative partition-related protein; n=1... 32 9.4
UniRef50_Q47706 Cluster: Membrane-associated protein uidC precur... 32 9.4
>UniRef50_P08249 Cluster: Malate dehydrogenase, mitochondrial
precursor; n=514; cellular organisms|Rep: Malate
dehydrogenase, mitochondrial precursor - Mus musculus
(Mouse)
Length = 338
Score = 164 bits (398), Expect = 1e-39
Identities = 84/149 (56%), Positives = 105/149 (70%)
Frame = +3
Query: 48 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 227
M S +PA A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALARPAGAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 228 IAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNT 407
IA TPGVAADLSH+ T A V G+ GPE+L +K DVVVIP GVPR+PGMTRDDLFNT
Sbjct: 58 IAH-TPGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116
Query: 408 NASIVRDIALSIAXNAPKAIVAIITNPVN 494
NA+IV + + A + P+A+V II NPVN
Sbjct: 117 NATIVATLTAACAQHCPEAMVCIIANPVN 145
>UniRef50_P40926 Cluster: Malate dehydrogenase, mitochondrial
precursor; n=119; cellular organisms|Rep: Malate
dehydrogenase, mitochondrial precursor - Homo sapiens
(Human)
Length = 338
Score = 162 bits (393), Expect = 5e-39
Identities = 81/149 (54%), Positives = 105/149 (70%)
Frame = +3
Query: 48 MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 227
M S +P + A++ ++FST++Q N K IGQPL+LLLK +PLV+RL LYD
Sbjct: 1 MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57
Query: 228 IAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNT 407
IA TPGVAADLSH+ T A V G+ GPE+L +K DVVVIP GVPR+PGMTRDDLFNT
Sbjct: 58 IAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116
Query: 408 NASIVRDIALSIAXNAPKAIVAIITNPVN 494
NA+IV + + A + P+A++ +I NPVN
Sbjct: 117 NATIVATLTAACAQHCPEAMICVIANPVN 145
>UniRef50_A2QMH9 Cluster: Malate dehydrogenase; n=7; Fungi/Metazoa
group|Rep: Malate dehydrogenase - Aspergillus niger
Length = 340
Score = 146 bits (354), Expect = 3e-34
Identities = 73/133 (54%), Positives = 98/133 (73%), Gaps = 1/133 (0%)
Frame = +3
Query: 99 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNT 278
++FS ++ + K IGQPL+LL+KQNPLVT LALYDI PGVAAD+SH+NT
Sbjct: 14 RSFSASASQASKVAVLGAAGGIGQPLSLLMKQNPLVTDLALYDIRG-GPGVAADISHINT 72
Query: 279 PAKVSGHKG-PEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNA 455
+ V G++ P L A+K +++++IP GVPR+PGMTRDDLFNTNASIVRD+A + A A
Sbjct: 73 NSTVKGYEPTPSGLRDALKGSEIILIPAGVPRKPGMTRDDLFNTNASIVRDLAKAAAEAA 132
Query: 456 PKAIVAIITNPVN 494
P+A + +I+NPVN
Sbjct: 133 PEANILVISNPVN 145
>UniRef50_Q9SN86 Cluster: Malate dehydrogenase, chloroplast
precursor; n=41; cellular organisms|Rep: Malate
dehydrogenase, chloroplast precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 403
Score = 143 bits (346), Expect = 3e-33
Identities = 69/111 (62%), Positives = 86/111 (77%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDAD 341
IGQPL+LL+K +PLV+ L LYDIA V GVAADLSH NTP++V GP EL+ +KD +
Sbjct: 94 IGQPLSLLIKMSPLVSTLHLYDIANVK-GVAADLSHCNTPSQVRDFTGPSELADCLKDVN 152
Query: 342 VVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
VVVIP GVPR+PGMTRDDLFN NA+IV+ + ++A N P A + II+NPVN
Sbjct: 153 VVVIPAGVPRKPGMTRDDLFNINANIVKTLVEAVAENCPNAFIHIISNPVN 203
>UniRef50_Q9Y7R8 Cluster: Malate dehydrogenase; n=13; Dikarya|Rep:
Malate dehydrogenase - Schizosaccharomyces pombe
(Fission yeast)
Length = 341
Score = 140 bits (338), Expect = 2e-32
Identities = 71/133 (53%), Positives = 91/133 (68%), Gaps = 1/133 (0%)
Frame = +3
Query: 99 KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNT 278
++FSTTS R FK IGQPL++LLK N V+ LAL+DI PGVAAD+ H+NT
Sbjct: 19 RSFSTTSSRAFKVAVLGAGGGIGQPLSMLLKLNDKVSELALFDIRGA-PGVAADIGHINT 77
Query: 279 PAKVSGHKGPEE-LSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNA 455
+ V G+ ++ L A+ ADVV+IP GVPR+PGMTRDDLF TNASIVRD+A +
Sbjct: 78 TSNVVGYAPDDKGLEKALNGADVVIIPAGVPRKPGMTRDDLFATNASIVRDLAFAAGETC 137
Query: 456 PKAIVAIITNPVN 494
P+A ++TNPVN
Sbjct: 138 PEAKYLVVTNPVN 150
>UniRef50_Q42972 Cluster: Malate dehydrogenase, glyoxysomal
precursor; n=11; Eukaryota|Rep: Malate dehydrogenase,
glyoxysomal precursor - Oryza sativa subsp. japonica
(Rice)
Length = 356
Score = 135 bits (326), Expect = 7e-31
Identities = 69/122 (56%), Positives = 82/122 (67%)
Frame = +3
Query: 129 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGP 308
FK IGQPLALL+K NPLV+ L LYD+ TPGV AD+SH+NT A V G G
Sbjct: 45 FKVAILGASGGIGQPLALLMKMNPLVSVLHLYDVVN-TPGVTADISHMNTGAVVRGFLGQ 103
Query: 309 EELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNP 488
+L A+ D+V+IP GVPR+PGMTRDDLFN NA IVR + IA P AIV +I+NP
Sbjct: 104 PQLENALTGMDLVIIPAGVPRKPGMTRDDLFNINAGIVRTLCEGIAKCCPNAIVNVISNP 163
Query: 489 VN 494
VN
Sbjct: 164 VN 165
>UniRef50_A3BMG8 Cluster: Putative uncharacterized protein; n=3;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 405
Score = 126 bits (304), Expect = 3e-28
Identities = 65/115 (56%), Positives = 79/115 (68%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDAD 341
IGQPL+LL+K +PLV+ L LYDIA V GV ADL H NTPAKV+G G EEL+ + D
Sbjct: 89 IGQPLSLLVKMSPLVSALHLYDIANVD-GVTADLGHCNTPAKVAGFTGKEELAGCLAGVD 147
Query: 342 VVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSA 506
VVVIP GVPR+PGMTRDDLF NA IVR++ ++A +AP A P + A
Sbjct: 148 VVVIPAGVPRKPGMTRDDLFGINAGIVRELVEAVADHAPAGAGARHLQPGELHRA 202
>UniRef50_Q6BM17 Cluster: Malate dehydrogenase; n=4; Eukaryota|Rep:
Malate dehydrogenase - Debaryomyces hansenii (Yeast)
(Torulaspora hansenii)
Length = 346
Score = 124 bits (299), Expect = 1e-27
Identities = 64/116 (55%), Positives = 84/116 (72%), Gaps = 5/116 (4%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEE-----LSXA 326
IGQPL+LLLK NP V+ L+L+D+ GVAADLSH+ +PAKV+G++ + + A
Sbjct: 13 IGQPLSLLLKLNPQVSELSLFDVVNAN-GVAADLSHICSPAKVTGYQPSSKEDRDTIQKA 71
Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+ ++D+VVIP GVPR+PGMTR DLFN NASI+RDI SI P A + II+NPVN
Sbjct: 72 LVNSDLVVIPAGVPRKPGMTRADLFNINASIIRDIVGSIGKACPNAAILIISNPVN 127
>UniRef50_Q6FL22 Cluster: Malate dehydrogenase; n=1; Candida
glabrata|Rep: Malate dehydrogenase - Candida glabrata
(Yeast) (Torulopsis glabrata)
Length = 373
Score = 120 bits (288), Expect = 3e-26
Identities = 59/111 (53%), Positives = 80/111 (72%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDAD 341
+GQPL+LLLK N +++ LALYDI + GVA DLSH+NT A G+ +++ A+K A
Sbjct: 13 VGQPLSLLLKLNTMISELALYDIK-LAEGVATDLSHINTNADCVGYS-TDDIGQALKGAA 70
Query: 342 VVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
VVVIP GVPR PG+TRDDLF NA IV+++ ++A + P A + II+NPVN
Sbjct: 71 VVVIPAGVPRRPGITRDDLFKLNAGIVKNLVSNVAKHCPNARLLIISNPVN 121
>UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5;
Protostomia|Rep: Malate dehydrogenase - Drosophila
melanogaster (Fruit fly)
Length = 347
Score = 118 bits (285), Expect = 6e-26
Identities = 59/124 (47%), Positives = 79/124 (63%)
Frame = +3
Query: 123 RNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHK 302
R K IGQPL+LLLK NP ++ L+LYDI T GV DLSH+NT A V +
Sbjct: 26 RGLKVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDIKNTT-GVGVDLSHINTRASVCPFE 84
Query: 303 GPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIIT 482
G L A+ AD+VVIP G+PR+PGM R+DL + NAS+ ++A + + P A++A IT
Sbjct: 85 GKNGLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVCPGAMLAFIT 144
Query: 483 NPVN 494
NP+N
Sbjct: 145 NPIN 148
>UniRef50_A7SQS1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 254
Score = 117 bits (282), Expect = 1e-25
Identities = 52/83 (62%), Positives = 69/83 (83%)
Frame = +3
Query: 246 GVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVR 425
GVAADLSH++T AKV+ H+GP++L A++ VV IP GVPR+PGMTRDDLFNTNASIV+
Sbjct: 7 GVAADLSHISTRAKVTSHQGPDDLKAALEGCSVVAIPAGVPRKPGMTRDDLFNTNASIVK 66
Query: 426 DIALSIAXNAPKAIVAIITNPVN 494
+++ + A + PKAI+ II+NPVN
Sbjct: 67 NLSEACAKHCPKAIICIISNPVN 89
>UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 365
Score = 117 bits (282), Expect = 1e-25
Identities = 55/112 (49%), Positives = 79/112 (70%), Gaps = 1/112 (0%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDAD 341
IGQPL+LLLK NP V+ LALYDI+ +T GVA DLSH+NT + G+ E+ ++ ++
Sbjct: 13 IGQPLSLLLKLNPYVSDLALYDISDITAGVAKDLSHINTNSDSEGYNKDEDFKNLLEGSE 72
Query: 342 VVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAP-KAIVAIITNPVN 494
+V++ G+PR+PGMTRDDLF NA I++++ + A AP + II+NPVN
Sbjct: 73 LVIVTAGIPRKPGMTRDDLFKINAKIIQNLTVKYAKFAPVHCKLLIISNPVN 124
>UniRef50_P32419 Cluster: Malate dehydrogenase, peroxisomal; n=24;
Eukaryota|Rep: Malate dehydrogenase, peroxisomal -
Saccharomyces cerevisiae (Baker's yeast)
Length = 343
Score = 111 bits (268), Expect = 7e-24
Identities = 53/111 (47%), Positives = 75/111 (67%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDAD 341
+GQPL+LLLK +P V+ LALYDI G+ DLSH+NT + G+ + + + +A
Sbjct: 13 VGQPLSLLLKLSPYVSELALYDIR-AAEGIGKDLSHINTNSSCVGYD-KDSIENTLSNAQ 70
Query: 342 VVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
VV+IP GVPR+PG+TRDDLF NA IV+ + ++ AP A + +I+NPVN
Sbjct: 71 VVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVN 121
>UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3;
Leishmania|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 331
Score = 111 bits (267), Expect = 1e-23
Identities = 61/123 (49%), Positives = 81/123 (65%), Gaps = 1/123 (0%)
Frame = +3
Query: 129 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGHKG 305
FK IGQPLAL L QN V+ LALYDI V P GVA DLSH KV+G+
Sbjct: 9 FKVTVLGASGAIGQPLALALVQNKRVSELALYDI--VQPRGVAVDLSHFPRKVKVTGYP- 65
Query: 306 PEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITN 485
+ + A+ AD+V++ G+PR PGMT DDLFNTNA V +++ ++A APK+++AII+N
Sbjct: 66 TKWIHKALDGADLVLMSAGMPRRPGMTHDDLFNTNALTVNELSAAVARYAPKSVLAIISN 125
Query: 486 PVN 494
P+N
Sbjct: 126 PLN 128
>UniRef50_Q9VU28 Cluster: Malate dehydrogenase; n=3; Sophophora|Rep:
Malate dehydrogenase - Drosophila melanogaster (Fruit
fly)
Length = 349
Score = 106 bits (255), Expect = 3e-22
Identities = 54/124 (43%), Positives = 77/124 (62%)
Frame = +3
Query: 123 RNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHK 302
R K IGQPL+LLL++ P + LAL+D++ + G+A DLSH++ KV G
Sbjct: 21 RTLKVAVVGAGGGIGQPLSLLLRRCPGIDELALHDLSEMK-GIATDLSHISQTGKVIGFT 79
Query: 303 GPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIIT 482
G +EL A+ ADVVV+ G+PR PGM RD L N ++ +A +I+ +P+A +A IT
Sbjct: 80 GEKELESAVSGADVVVVAAGMPRLPGMQRDHLMAANGNVAVKVATAISNASPRAHLAFIT 139
Query: 483 NPVN 494
NPVN
Sbjct: 140 NPVN 143
>UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep:
ADL164Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 381
Score = 104 bits (249), Expect = 1e-21
Identities = 65/127 (51%), Positives = 77/127 (60%), Gaps = 16/127 (12%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVT--------RLALYDIAP-VTPGVAADLSHVNTPAKVSGH----- 299
IGQPL+LLLK LALYD+A GVAADLSHVNTP +VS H
Sbjct: 35 IGQPLSLLLKTQLAQVLGDANASLELALYDVAADALAGVAADLSHVNTPVEVSHHVPSSR 94
Query: 300 KGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSI--AXNAPKAIVA 473
+ E L A+ A VVVIP GVPR+PGMTRDDL N NA I++ +A I A + K V
Sbjct: 95 EDEEALREALTGASVVVIPAGVPRKPGMTRDDLININAGIIKTLAKGIAGACDLEKVFVL 154
Query: 474 IITNPVN 494
+I+NPVN
Sbjct: 155 VISNPVN 161
>UniRef50_Q4QDF0 Cluster: Glycosomal malate dehydrogenase; n=9;
Trypanosomatidae|Rep: Glycosomal malate dehydrogenase -
Leishmania major
Length = 322
Score = 102 bits (244), Expect = 6e-21
Identities = 59/119 (49%), Positives = 76/119 (63%), Gaps = 8/119 (6%)
Frame = +3
Query: 162 IGQPLALLL-KQNPLVTRLALYDIAPVTPGVAADLSHV-NTPAKVS------GHKGPEEL 317
IGQ L+LLL +Q P + L+L+D+ GVAADLSHV N +V GHK L
Sbjct: 13 IGQSLSLLLVRQLPYGSTLSLFDVVGAA-GVAADLSHVDNAGVQVKFAEGKIGHKRDPAL 71
Query: 318 SXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+ K DV V+ GVPR+PGMTRDDLF NA I+ D+ L+ A ++PKA+ I+TNPVN
Sbjct: 72 AELAKGVDVFVMVAGVPRKPGMTRDDLFKINAGIILDLVLTCASSSPKAVFCIVTNPVN 130
>UniRef50_P22133 Cluster: Malate dehydrogenase, cytoplasmic; n=3;
Saccharomycetaceae|Rep: Malate dehydrogenase,
cytoplasmic - Saccharomyces cerevisiae (Baker's yeast)
Length = 377
Score = 99.5 bits (237), Expect = 4e-20
Identities = 63/136 (46%), Positives = 80/136 (58%), Gaps = 14/136 (10%)
Frame = +3
Query: 162 IGQPLALLLK---------QNPLVTR--LALYDI-APVTPGVAADLSHVNTPAKVSGHKG 305
IGQ L+LLLK N VT LALYD+ GV ADLSH++TP VS H
Sbjct: 25 IGQSLSLLLKAQLQYQLKESNRSVTHIHLALYDVNQEAINGVTADLSHIDTPISVSSHSP 84
Query: 306 PEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIA--XNAPKAIVAII 479
+ + +A +VVIP GVPR+PGMTRDDLFN NA I+ + SIA + K V +I
Sbjct: 85 AGGIENCLHNASIVVIPAGVPRKPGMTRDDLFNVNAGIISQLGDSIAECCDLSKVFVLVI 144
Query: 480 TNPVNFYSALLPLKCS 527
+NPVN +L+P+ S
Sbjct: 145 SNPVN---SLVPVMVS 157
>UniRef50_A7TSF5 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 387
Score = 96.3 bits (229), Expect = 4e-19
Identities = 59/125 (47%), Positives = 79/125 (63%), Gaps = 6/125 (4%)
Frame = +3
Query: 162 IGQPLALLLK-----QNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSX 323
IGQ L+LLL+ N LAL+D+ V GV ADLSHVNT K+S H + L
Sbjct: 52 IGQSLSLLLRTSLQNNNDNQLHLALFDVNMKVLNGVHADLSHVNTNMKLSLH---DNLRD 108
Query: 324 AIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYS 503
++ D+++V+IP GVPR+PGMTRDDLFN NA I++ IA + V +I+NPVN
Sbjct: 109 SLVDSNLVIIPAGVPRKPGMTRDDLFNINAGIIKGIAQELNTIDSTPFVLLISNPVN--- 165
Query: 504 ALLPL 518
+LLP+
Sbjct: 166 SLLPV 170
>UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa
triquetra|Rep: Malate dehydrogenase - Heterocapsa
triquetra (Dinoflagellate)
Length = 402
Score = 89.0 bits (211), Expect = 6e-17
Identities = 51/131 (38%), Positives = 70/131 (53%), Gaps = 9/131 (6%)
Frame = +3
Query: 129 FKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI-APVTP--GVAADLSHVNTPAKVSGH 299
FK IGQPL LL+ +P V L ++D+ + P GVA DL H+ A V G+
Sbjct: 81 FKVCVCGGAGGIGQPLCLLMAMDPNVKELCVFDLNVAMVPAQGVATDLGHLEKKAAVKGY 140
Query: 300 ------KGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPK 461
K + L + +V+IP G+PR+PG TRDDLF NA I + I + A P
Sbjct: 141 VMEVGQKPVDNLEECLTGCHLVLIPAGMPRKPGQTRDDLFKINADIAKGIVEACAKYCPD 200
Query: 462 AIVAIITNPVN 494
A++ +I NPVN
Sbjct: 201 AMLGMIVNPVN 211
>UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces
cerevisiae YOL126c MDH2 malate dehydrogenase; n=1;
Kluyveromyces lactis|Rep: Similar to sp|P22133
Saccharomyces cerevisiae YOL126c MDH2 malate
dehydrogenase - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 404
Score = 87.4 bits (207), Expect = 2e-16
Identities = 55/132 (41%), Positives = 75/132 (56%), Gaps = 15/132 (11%)
Frame = +3
Query: 162 IGQPLALLLKQN-----PLVT----RLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPE 311
IGQ L+LLLK N P T RL+LYD+ G AADLSH++TP + H +
Sbjct: 58 IGQSLSLLLKSNAGFLLPHETSTHIRLSLYDVNKDAIVGTAADLSHIDTPITTTAHYPDD 117
Query: 312 E---LSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIA--XNAPKAIVAI 476
+ + +A VV+IP GVPR+PGM+RDDL NA I++ + IA + K V +
Sbjct: 118 SNGGIGQCLSNASVVIIPAGVPRKPGMSRDDLIGVNAKIIKSLGEDIAKYCDLNKVHVLV 177
Query: 477 ITNPVNFYSALL 512
I+NP+N LL
Sbjct: 178 ISNPINSLVPLL 189
>UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|Rep:
Malate dehydrogenase - Plasmodium falciparum
Length = 313
Score = 72.5 bits (170), Expect = 5e-12
Identities = 39/96 (40%), Positives = 58/96 (60%), Gaps = 2/96 (2%)
Frame = +3
Query: 213 LALYDIAPVTP-GVAADLSHVNTPAKVSGH-KGPEELSXAIKDADVVVIPXGVPREPGMT 386
L LYD+ P P G A DL H +T V+ + G ++ IKDAD++VI GV R+ GMT
Sbjct: 28 LILYDVVPGIPQGKALDLKHFSTILGVNRNILGTNQIED-IKDADIIVITAGVQRKEGMT 86
Query: 387 RDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
R+DL N I++ +A S+ + KA V ++NP++
Sbjct: 87 REDLIGVNGKIMKSVAESVKLHCSKAFVICVSNPLD 122
>UniRef50_UPI0000D571DB Cluster: PREDICTED: similar to CG7998-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG7998-PA - Tribolium castaneum
Length = 376
Score = 72.1 bits (169), Expect = 7e-12
Identities = 38/110 (34%), Positives = 65/110 (59%)
Frame = +3
Query: 165 GQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADV 344
G+ ++L+LKQ+P + L LYD + G A DL++V+T +V+ G +++ A+ +++
Sbjct: 41 GKSVSLMLKQSPFIDELCLYDTQSLE-GFANDLNYVDTKCRVTSFFGNKDIQKALTKSNI 99
Query: 345 VVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+V+ LF+ NA IV+D+A SIA +PK+ VAI P+N
Sbjct: 100 IVVLSCCHAAEPTNYASLFDRNAPIVKDLATSIAKFSPKSTVAIGVEPIN 149
>UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 330
Score = 70.5 bits (165), Expect = 2e-11
Identities = 33/64 (51%), Positives = 46/64 (71%)
Frame = +3
Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSA 506
I DA +V+I GVPR+PGM+R DL TNA IVR +A +IA AP A+V +++NP++ +A
Sbjct: 85 IADASIVIITAGVPRKPGMSRMDLLETNARIVRGVAENIAKYAPSAVVIVVSNPLDEMTA 144
Query: 507 LLPL 518
L L
Sbjct: 145 LTQL 148
>UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;
n=2; Apis mellifera|Rep: PREDICTED: similar to CG7998-PA
- Apis mellifera
Length = 333
Score = 70.1 bits (164), Expect = 3e-11
Identities = 42/119 (35%), Positives = 72/119 (60%), Gaps = 1/119 (0%)
Frame = +3
Query: 165 GQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEE-LSXAIKDAD 341
G L+L LKQ+PL+ LA++D T G+A DL++++T KVS PE+ L ++ A
Sbjct: 13 GNCLSLFLKQSPLIDELAIFDNNSSTYGLALDLNYIDTKCKVSTCNHPEKCLEETLQGAK 72
Query: 342 VVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSALLPL 518
+V+I V +++ +NA I+ D+ +I +P+A++AI+ NP+N +L+PL
Sbjct: 73 IVMI---VTDRTSNESNEVLKSNAIILSDLLPNIIKFSPQAMLAIVMNPIN---SLIPL 125
>UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2;
Toxoplasma gondii|Rep: Mitochondrial
malate-dehydrogenase - Toxoplasma gondii
Length = 470
Score = 70.1 bits (164), Expect = 3e-11
Identities = 45/123 (36%), Positives = 65/123 (52%), Gaps = 2/123 (1%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGH-KGPEELSXAIKD 335
IG LALL L + ++D+ P G DL + + V +G + S +KD
Sbjct: 168 IGATLALLSAVKELGD-VVMFDVVQDLPQGKCLDLYQLTPISGVDVRFEGSNDYS-VLKD 225
Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSALLP 515
ADV+++ GVPR+PGM+RDDL NA I+ + +I P A V ITNP++ +L
Sbjct: 226 ADVIIVTAGVPRKPGMSRDDLLAINAKIMGQVGEAIKQYCPNAFVICITNPLDVMVYILR 285
Query: 516 LKC 524
KC
Sbjct: 286 EKC 288
>UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobus
fulgidus|Rep: Malate dehydrogenase - Archaeoglobus
fulgidus
Length = 294
Score = 68.9 bits (161), Expect = 7e-11
Identities = 41/119 (34%), Positives = 67/119 (56%), Gaps = 2/119 (1%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVNTPA-KVSGHKGPEELSXAIKD 335
+G A N V +AL DIA + G A DL+H K G + S +K
Sbjct: 11 VGSTSAFTCLLNLDVDEIALVDIAEDLAVGEAMDLAHAAAGIDKYPKIVGGADYSL-LKG 69
Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSALL 512
++++V+ G+ R+PGMTR DL + NA I++DIA I NAP++ + ++TNP++ + ++
Sbjct: 70 SEIIVVTAGLARKPGMTRLDLAHKNAGIIKDIAKKIVENAPESKILVVTNPMDVMTYIM 128
>UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5;
Gammaproteobacteria|Rep: Malate dehydrogenase -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 311
Score = 68.1 bits (159), Expect = 1e-10
Identities = 42/116 (36%), Positives = 64/116 (55%), Gaps = 5/116 (4%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSH----VNTPAKVSGHKGPEELSXA 326
+G+ A L +N L L L D V G A D+ + A+V+G E
Sbjct: 14 VGEATAQFLVKNELCRELVLLDAQEGVAQGAALDIQQSAPLFDFDARVTGSTNYE----L 69
Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
I D+D+VVI G PR+PGM+R D+ ++N I+ DI ++ AP+++V I+TNPV+
Sbjct: 70 IADSDLVVITAGKPRKPGMSRSDVLDSNLPIITDIMNNVMRFAPQSLVMIVTNPVD 125
>UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular
organisms|Rep: Malate dehydrogenase - Silicibacter
pomeroyi
Length = 320
Score = 67.3 bits (157), Expect = 2e-10
Identities = 43/113 (38%), Positives = 60/113 (53%), Gaps = 2/113 (1%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGH-KGPEELSXAIKD 335
IG LA L+ L + L+DIA TP G A D++ KG + + I
Sbjct: 14 IGGTLAHLVALKELGD-VVLFDIAEGTPEGKALDIAESGPSEGFDAKLKGTQSYAD-IAG 71
Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
ADV ++ GVPR+PGM+RDDL N +++ + I NAP A V ITNP++
Sbjct: 72 ADVCIVTAGVPRKPGMSRDDLLGINLKVMKSVGEGIRDNAPDAFVICITNPLD 124
>UniRef50_UPI0000D55CD8 Cluster: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1); n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Malate
DeHydrogenase family member (mdh-1) - Tribolium
castaneum
Length = 374
Score = 66.5 bits (155), Expect = 4e-10
Identities = 43/119 (36%), Positives = 64/119 (53%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDAD 341
+G LALLLKQN + L L+D T A DL+ ++T K+ + L AI A
Sbjct: 40 VGSNLALLLKQNLDIYELRLFDEENNTNAFACDLNEIDTRTKLKSFSC-KSLKNAIVGAH 98
Query: 342 VVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSALLPL 518
VV+ G +PG ++ +LF+ N VR++A+ +A P+AI I PV AL+P+
Sbjct: 99 VVISTGGCQEKPGSSQRELFDKNLDNVRNVAMFLAEFNPEAIYCIAKPPV---EALVPM 154
>UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14;
Thermoprotei|Rep: Malate dehydrogenase - Pyrobaculum
aerophilum
Length = 309
Score = 66.5 bits (155), Expect = 4e-10
Identities = 37/113 (32%), Positives = 64/113 (56%), Gaps = 2/113 (1%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVS-GHKGPEELSXAIKD 335
+G A+++ L ++ L DI P G A D++H+++ + + G E I+
Sbjct: 10 VGTAAAVIMGLMKLDNKILLIDIVKGLPQGEALDMNHMSSILGLDVEYVGSNEYKD-IEG 68
Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+D++++ G+PR+PGMTR+ L NA IV +I I AP +IV + TNP++
Sbjct: 69 SDLIIVTAGLPRKPGMTREQLLEANAKIVAEIGREIKKYAPDSIVILTTNPLD 121
>UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=1;
Sulfurovum sp. NBC37-1|Rep: Malate dehydrogenase,
NAD-dependent - Sulfurovum sp. (strain NBC37-1)
Length = 320
Score = 65.7 bits (153), Expect = 6e-10
Identities = 44/118 (37%), Positives = 63/118 (53%), Gaps = 8/118 (6%)
Frame = +3
Query: 165 GQPLALLLKQNPLVTRLAL----YDIAPVTPGVAADLSHVNTPAK----VSGHKGPEELS 320
G +A +L N + L YD+A G A D+S A+ V KGPE++
Sbjct: 16 GSTVAFILAMNGSCHHVMLRGRNYDVAK---GKALDMSQAANAARQHTIVKAAKGPEDM- 71
Query: 321 XAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+ +DVV+I G PR PGM+RDDL NA IV+ + I AP AIV +++NP++
Sbjct: 72 ---EGSDVVIITAGAPRTPGMSRDDLLFKNADIVKCYSREIKEYAPDAIVIVVSNPLD 126
>UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep:
Malate dehydrogenase - Brucella melitensis
Length = 320
Score = 65.7 bits (153), Expect = 6e-10
Identities = 38/97 (39%), Positives = 57/97 (58%), Gaps = 3/97 (3%)
Frame = +3
Query: 213 LALYDIAPVTP-GVAADLSHVNTPAKVSGHK--GPEELSXAIKDADVVVIPXGVPREPGM 383
+ L+DIA TP G D++ ++P K G + + AI+ ADVV++ GVPR+PGM
Sbjct: 30 VVLFDIAEGTPQGKGLDIAE-SSPVDGFDAKFTGANDYA-AIEGADVVIVTAGVPRKPGM 87
Query: 384 TRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+RDDL N ++ + I AP+A V ITNP++
Sbjct: 88 SRDDLLGINLKVMEQVGAGIKKYAPEAFVICITNPLD 124
>UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacter
hominis ATCC BAA-381|Rep: Malate dehydrogenase -
Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 /
NCTC 13146 /CH001A)
Length = 297
Score = 65.3 bits (152), Expect = 8e-10
Identities = 40/102 (39%), Positives = 61/102 (59%), Gaps = 5/102 (4%)
Frame = +3
Query: 204 VTRLALYDI-APVTPGVAADLSHV----NTPAKVSGHKGPEELSXAIKDADVVVIPXGVP 368
++++AL DI + A DLSH+ N ++SG E L +K++D+VVI G
Sbjct: 26 ISQIALIDIFGDLAKARALDLSHLASVYNKKTEISG-SSDETL---LKNSDIVVITAGKT 81
Query: 369 REPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
R+ G +R DL N NA I+ A ++A AP+AI+ +ITNPV+
Sbjct: 82 RQAGQSRADLLNDNAKIISSCAKNVAKYAPEAIIILITNPVD 123
>UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;
Ignicoccus hospitalis KIN4/I|Rep: malate dehydrogenase
(NAD) - Ignicoccus hospitalis KIN4/I
Length = 311
Score = 64.5 bits (150), Expect = 1e-09
Identities = 38/118 (32%), Positives = 58/118 (49%), Gaps = 1/118 (0%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
+G A + P V R+ L D P ++ GV D+ H + S + +++A
Sbjct: 16 VGATFAYTMAIVPGVARMVLVDAVPGLSKGVMEDIKHAAAVFRRSIQVEAYDDVSKVENA 75
Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSALL 512
D +VI G PR+ M+R DL NA I+RDI + P A +ITNPV+ + +L
Sbjct: 76 DAIVITAGKPRKADMSRRDLAKVNAQIIRDIGDKLRDRNPGAFYMVITNPVDVMTMIL 133
>UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like
protein; n=1; Methylibium petroleiphilum PM1|Rep:
Malate/lactate dehydrogenases-like protein - Methylibium
petroleiphilum (strain PM1)
Length = 432
Score = 64.5 bits (150), Expect = 1e-09
Identities = 36/111 (32%), Positives = 59/111 (53%), Gaps = 1/111 (0%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
+G AL L ++ L + +AL D+ P + G+A D+ H S + A+ A
Sbjct: 134 VGAMTALRLAESDLFSEVALVDVVPGLAAGLALDMWHGAGLYGFSTRLSGSDDLVALAGA 193
Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPV 491
+ +VI G PR+PGM+R DL NA I+ + I +AP + + I++NP+
Sbjct: 194 EYIVITAGKPRQPGMSRTDLTVVNAEIMTSVCRGIRTHAPNSTLVIVSNPL 244
>UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter
hepaticus|Rep: Malate dehydrogenase - Helicobacter
hepaticus
Length = 315
Score = 62.5 bits (145), Expect = 6e-09
Identities = 37/117 (31%), Positives = 67/117 (57%), Gaps = 6/117 (5%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALY--DIAPVTPGVAADLSHV----NTPAKVSGHKGPEELSX 323
+G +A L + + L+ DI P GV D+S + P + G EE++
Sbjct: 14 VGSHIAFLGAMRHIAKEILLFSNDI-PRCKGVGLDISQAAAIFDIPILIKGCNSYEEIA- 71
Query: 324 AIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+++VV+I G PR P MTR+DL NASI+++I+ ++A AP++++ +++NP++
Sbjct: 72 ---ESEVVIITAGFPRTPNMTRNDLLLKNASIIQEISSNVARIAPQSLLIVVSNPLD 125
>UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28;
Bacteroidetes|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 313
Score = 62.5 bits (145), Expect = 6e-09
Identities = 25/54 (46%), Positives = 41/54 (75%)
Frame = +3
Query: 333 DADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
++DVVVI G+PR+PGMTR++L NA IV+ +A ++ +P AI+ +I+NP++
Sbjct: 71 NSDVVVITSGIPRKPGMTREELIGVNAGIVKSVAENLLKYSPNAIIVVISNPMD 124
>UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD binding
domain protein; n=2; Campylobacter|Rep: Lactate/malate
dehydrogenase, NAD binding domain protein -
Campylobacter curvus 525.92
Length = 297
Score = 60.9 bits (141), Expect = 2e-08
Identities = 38/113 (33%), Positives = 59/113 (52%), Gaps = 2/113 (1%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTP-AKVSGHKGPEELSXAIKD 335
+G +A L + +AL DI V A D++ G ++ + I+
Sbjct: 11 VGASIAYALAMRGVCDEIALVDIFGDVARAKAIDIAQAGCVFCGCLSTAGGDDFAL-IEA 69
Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+D+VV+ G PR+ G TR+DL NA +V+ A +IA AP AIV I+TNP++
Sbjct: 70 SDIVVVTAGSPRKEGQTREDLLLKNAQVVKQTAQNIAKFAPNAIVIIVTNPLD 122
>UniRef50_UPI00005A0834 Cluster: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor; n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor - Canis
familiaris
Length = 245
Score = 60.5 bits (140), Expect = 2e-08
Identities = 25/43 (58%), Positives = 34/43 (79%)
Frame = +3
Query: 366 PREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
PR+PGMTRDDLFNTNAS+V + A + P+A++ +I+NPVN
Sbjct: 61 PRKPGMTRDDLFNTNASVVATPTAACAQHCPEAMICVISNPVN 103
>UniRef50_P11386 Cluster: Malate dehydrogenase; n=6;
Sulfolobaceae|Rep: Malate dehydrogenase - Sulfolobus
acidocaldarius
Length = 306
Score = 60.5 bits (140), Expect = 2e-08
Identities = 36/117 (30%), Positives = 56/117 (47%), Gaps = 1/117 (0%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPG-VAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
+GQ +A N + LYD+ P P ++ H +V I A
Sbjct: 12 VGQTIAYNTIVNGYADEVMLYDVVPELPEKFEHEIRHALAALRVKTELLSTNNIDDISGA 71
Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSAL 509
D+VVI G PR+PGM+R DLF NA I+ D+A + A+ ++ NPV+ +++
Sbjct: 72 DIVVITAGKPRKPGMSRRDLFIDNAKIMIDLAKKLPKKNKGAMYIMVANPVDMMASV 128
>UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2;
Euryarchaeota|Rep: Malate dehydrogenase - Methanopyrus
kandleri
Length = 317
Score = 60.5 bits (140), Expect = 2e-08
Identities = 26/54 (48%), Positives = 38/54 (70%)
Frame = +3
Query: 333 DADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
DADV+V+ G+PR+PG TR DL NA+I++ +A P+AIV ++TNPV+
Sbjct: 73 DADVIVMTAGIPRKPGQTRLDLTKDNAAIIKKYLEGVAEENPEAIVLVVTNPVD 126
>UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep:
Malate dehydrogenase 1 - Aquifex aeolicus
Length = 335
Score = 60.5 bits (140), Expect = 2e-08
Identities = 34/80 (42%), Positives = 49/80 (61%), Gaps = 2/80 (2%)
Frame = +3
Query: 261 LSHVNTPAKVSGHK-GPE-ELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIA 434
L+ ++ A+V G+ PE E ++ +D+VVI G PR PGM+R+DL N I+ IA
Sbjct: 59 LAAMDIDARVEGYTVTPEGEGYEPLEGSDIVVITAGFPRRPGMSREDLLEANIRIISVIA 118
Query: 435 LSIAXNAPKAIVAIITNPVN 494
I AP AIV ++TNPV+
Sbjct: 119 DRIKRYAPDAIVIVVTNPVD 138
>UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4;
Thermotogaceae|Rep: L-lactate dehydrogenase - Thermotoga
maritima
Length = 319
Score = 60.5 bits (140), Expect = 2e-08
Identities = 36/112 (32%), Positives = 59/112 (52%), Gaps = 1/112 (0%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
+G A L + L D+ G A DL H TP + + + +K +
Sbjct: 11 VGSSTAFALLMKGFAREMVLIDVDKKRAEGDALDLIH-GTPFTRRANIYAGDYAD-LKGS 68
Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
DVV++ GVP++PG TR L NA ++++IA +++ AP +IV ++TNPV+
Sbjct: 69 DVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYAPDSIVIVVTNPVD 120
>UniRef50_UPI0000D56DC5 Cluster: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Malate
dehydrogenase, mitochondrial precursor - Tribolium
castaneum
Length = 349
Score = 58.4 bits (135), Expect = 9e-08
Identities = 35/133 (26%), Positives = 66/133 (49%)
Frame = +3
Query: 96 AKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVN 275
+++F + Q++ + +GQ LA L+KQNP ++ L L + V +A D +H +
Sbjct: 11 SRHFCSKPQKHVQVCILGADTLLGQSLAFLIKQNPAISGLHLQGTSKV-ESMALDFNHFD 69
Query: 276 TPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNA 455
T +V + + +S ++K AD+VV+ M+ L V +A + A A
Sbjct: 70 TRCRVHSYYDMDSVSKSVKCADIVVMLGLNTSTSKMSIPKLVMAEGVRVAKLAETCAKYA 129
Query: 456 PKAIVAIITNPVN 494
PKA++ + P++
Sbjct: 130 PKAVIVVAVTPIS 142
>UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4;
Epsilonproteobacteria|Rep: Malate dehydrogenase -
Wolinella succinogenes
Length = 314
Score = 58.4 bits (135), Expect = 9e-08
Identities = 29/112 (25%), Positives = 56/112 (50%), Gaps = 1/112 (0%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
+G +A +L + + + D+ T G+A D+ H + K ++
Sbjct: 9 VGSTVAFILATQGICQEIIIKDLNLDTARGIALDMGHAASATKTHTIVRVANEPSDLRGC 68
Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
DVVV G PR+PGM+RDDL NA ++R + + ++++ +++NP++
Sbjct: 69 DVVVFCAGSPRQPGMSRDDLLLANAKVIRTVLSEVKPYIQESVLVMVSNPLD 120
>UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17;
Apicomplexa|Rep: L-lactate dehydrogenase - Plasmodium
falciparum (isolate CDC / Honduras)
Length = 316
Score = 58.0 bits (134), Expect = 1e-07
Identities = 46/127 (36%), Positives = 63/127 (49%), Gaps = 10/127 (7%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPA----KVSGHKGPEELSXA 326
IG +A L+ Q L + L+DI P G A D SH N A KVSG ++L+ A
Sbjct: 15 IGGVMATLIVQKNLGD-VVLFDIVKNMPHGKALDTSHTNVMAYSNCKVSGSNTYDDLAGA 73
Query: 327 IKDADVVVIPXGVPREPGMT-----RDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPV 491
DVV++ G + PG + RDDL N I+ +I I N P A + ++TNPV
Sbjct: 74 ----DVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKKNCPNAFIIVVTNPV 129
Query: 492 NFYSALL 512
+ LL
Sbjct: 130 DVMVQLL 136
>UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4;
Thermoplasmatales|Rep: Malate dehydrogenase -
Thermoplasma volcanium
Length = 325
Score = 57.2 bits (132), Expect = 2e-07
Identities = 21/62 (33%), Positives = 43/62 (69%)
Frame = +3
Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSA 506
++ +DV+V+ G+ R+PGM+R+DLF+ N I+ D++ +I +P +I+ +++NP + +
Sbjct: 74 MEGSDVIVVTAGMARKPGMSREDLFDKNVEIIADVSKNIKKYSPDSIIVVVSNPADIMAY 133
Query: 507 LL 512
L
Sbjct: 134 AL 135
>UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 319
Score = 57.2 bits (132), Expect = 2e-07
Identities = 35/95 (36%), Positives = 51/95 (53%), Gaps = 3/95 (3%)
Frame = +3
Query: 213 LALYDIAP-VTPGVAADLSHVN--TPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGM 383
++LYDIA ADL+H TPA V G + + D+DVV I G ++PG
Sbjct: 38 VSLYDIAKDKVEAEVADLAHGTQFTPASVMGGADVHDTA----DSDVVFITAGARQKPGQ 93
Query: 384 TRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNP 488
TR DL NA+I+R + + +P A+ ++TNP
Sbjct: 94 TRLDLAGVNANILRSLMPQLVEQSPNALFVLVTNP 128
>UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12;
Bacteria|Rep: L-lactate dehydrogenase - Clostridium
tetani
Length = 316
Score = 57.2 bits (132), Expect = 2e-07
Identities = 38/113 (33%), Positives = 57/113 (50%), Gaps = 2/113 (1%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSH-VNTPAKVSGHKGPEELSXAIKD 335
+G A L L + + + DI G A DLSH V+ V G E + KD
Sbjct: 16 VGSTTAYALMMEGLASEIVIVDINKEKAKGEAMDLSHGVSFVKPVDIIAGDYEDT---KD 72
Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+D+V+I G +PG TR DL N N I + I + +PK+I+ +++NPV+
Sbjct: 73 SDIVIITAGAGPKPGETRLDLINKNYEIFKGIVPEVVKYSPKSILLVVSNPVD 125
>UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 304
Score = 56.8 bits (131), Expect = 3e-07
Identities = 35/113 (30%), Positives = 60/113 (53%), Gaps = 2/113 (1%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGH-KGPEELSXAIKD 335
+G AL L ++ L D+A P G A D++H+ + + KG +K
Sbjct: 10 VGGDAALFSALKRLDDQILLLDVAEGLPQGEAMDINHMLSEQGIDVEVKGSNNFED-MKG 68
Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+++VV+ G R+PGMTR DL NASIV+ + ++ A +++ +TNP++
Sbjct: 69 SNIVVVVAGSGRKPGMTRMDLLKINASIVKSVVENVKKYADDSMIIPVTNPLD 121
>UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: Malate/L-lactate
dehydrogenase - Cenarchaeum symbiosum
Length = 302
Score = 56.4 bits (130), Expect = 4e-07
Identities = 33/113 (29%), Positives = 59/113 (52%), Gaps = 2/113 (1%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGH-KGPEELSXAIKD 335
+G A+ L + + L DI P G A D++H+ + +G + S ++
Sbjct: 10 VGGDAAMFCALRRLDSEILLLDIVEGLPQGEAMDINHMLAEQGIDTEVRGSNDYSD-MEG 68
Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+D+VV+ G R+PGMTR DL NA IV+ + + +A +++ +TNP++
Sbjct: 69 SDIVVVVAGAGRKPGMTRMDLLKINAGIVKGVVEKVKEHAKDSMIIPVTNPLD 121
>UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8;
Lactobacillus|Rep: L-lactate dehydrogenase 2 -
Lactobacillus plantarum
Length = 309
Score = 56.4 bits (130), Expect = 4e-07
Identities = 38/118 (32%), Positives = 56/118 (47%), Gaps = 2/118 (1%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHVNTPAKVSG-HKGPEELSXAIKD 335
+G A L QN + L + D+ G DL V + H G E + A +D
Sbjct: 16 VGSSFAFSLVQNCALDELVIVDLVKTHAEGDVKDLEDVAAFTNATNIHTG--EYADA-RD 72
Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSAL 509
AD+VVI GVPR+PG +R DL N N I+ I + + I +NPV+ +++
Sbjct: 73 ADIVVITAGVPRKPGESRLDLINRNTKILESIVKPVVASGFNGCFVISSNPVDILTSM 130
>UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular
organisms|Rep: Malate dehydrogenase - Gloeobacter
violaceus
Length = 325
Score = 56.0 bits (129), Expect = 5e-07
Identities = 40/119 (33%), Positives = 59/119 (49%), Gaps = 5/119 (4%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGHK----GPEELSXA 326
+G LA L Q V + L DI P G+ DL V GH G + +
Sbjct: 19 VGSALAQRLIQGN-VADVVLLDIVEGRPQGITLDLLEA---CGVEGHTCRITGTNDYAQT 74
Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYS 503
+DV+V+ G R+PGM+RDDL TN IV ++ ++P+A V ++TNP++ S
Sbjct: 75 A-GSDVLVVAAGFARQPGMSRDDLLLTNTRIVFEVTQKAVAHSPEATVVVVTNPLDAMS 132
>UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep: Malate/lactate
dehydrogenase - Leptospirillum sp. Group II UBA
Length = 320
Score = 54.8 bits (126), Expect = 1e-06
Identities = 23/62 (37%), Positives = 42/62 (67%)
Frame = +3
Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSA 506
I+ + VVV+ G R+PGM+R+DL + N I+ ++A I +AP ++V ++TNP++ +
Sbjct: 72 IEGSSVVVVTAGFSRKPGMSREDLLHKNGDIMIEVAEKIRKHAPDSVVIMVTNPMDLMAY 131
Query: 507 LL 512
+L
Sbjct: 132 IL 133
>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 2 - Entamoeba histolytica
Length = 329
Score = 54.8 bits (126), Expect = 1e-06
Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
Frame = +3
Query: 213 LALYDIAPVT-PGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTR 389
L LYD+ + G++ +L+ P K+ G E++ A + DV +I GVPR+PGM R
Sbjct: 47 LHLYDLNDMALKGLSMELTDCCLP-KLKGIISTTEIALAFSNVDVAIIVAGVPRKPGMQR 105
Query: 390 DDLFNTNASIVRDIALSIAXNAPKAI-VAIITNPVN 494
DL N N ++ ++ + K + V ++ NP N
Sbjct: 106 SDLINVNKKVMEMNGKALGTYSNKDVRVVVVANPAN 141
>UniRef50_Q4Q3J5 Cluster: Malate dehydrogenase, putative; n=5;
Trypanosomatidae|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 342
Score = 54.8 bits (126), Expect = 1e-06
Identities = 39/134 (29%), Positives = 64/134 (47%), Gaps = 5/134 (3%)
Frame = +3
Query: 108 STTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAP----VTPGVAADLSHVN 275
S T+ + K +GQPL+LLLK NP V L + A G+AADLSH++
Sbjct: 8 SLTALKKGKVVLFGCSNAVGQPLSLLLKMNPHVEELVCCNTAADDDVPGSGIAADLSHID 67
Query: 276 TPAKVSGHKGPEELSXAIKDADVVVIPXGVPRE-PGMTRDDLFNTNASIVRDIALSIAXN 452
T KV + ++DA ++++ G + RD A +R + ++A +
Sbjct: 68 TLPKVHYATDEGQWPALLRDAQLILVCFGSSFDLLREDRDIALKAAAPTMRRVMAAVASS 127
Query: 453 APKAIVAIITNPVN 494
VA++++PVN
Sbjct: 128 DTTGNVAVVSSPVN 141
>UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4;
Lactobacillus|Rep: L-lactate dehydrogenase -
Lactobacillus reuteri
Length = 312
Score = 54.4 bits (125), Expect = 2e-06
Identities = 31/85 (36%), Positives = 48/85 (56%)
Frame = +3
Query: 255 ADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIA 434
AD++ + P K+ + G E + DADVVVI G+PR+PG TR DL N N +I++ I
Sbjct: 53 ADITPLTNPVKI--YAGTYEDAA---DADVVVITAGIPRKPGETRLDLVNKNTTILKSII 107
Query: 435 LSIAXNAPKAIVAIITNPVNFYSAL 509
I + + I +NPV+ + +
Sbjct: 108 KPIVKSGFTGVFVISSNPVDILTTI 132
>UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2;
Planctomycetaceae|Rep: L-lactate/malate dehydrogenase -
Rhodopirellula baltica
Length = 304
Score = 53.6 bits (123), Expect = 3e-06
Identities = 36/113 (31%), Positives = 58/113 (51%), Gaps = 2/113 (1%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIA-PVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
+G +A L NPL + L L + + G A DL+H + E++ + KD+
Sbjct: 11 VGSAIAFALTINPLASELLLLNRSREKAEGDALDLTHAAALVDSNIKISSGEIADS-KDS 69
Query: 339 DVVVIPXGVP-REPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
DV++ VP R P TR ++ N I+RD +A +P AIV +++NPV+
Sbjct: 70 DVIIFTASVPFRYPNQTRLEMGIDNMPILRDWMPGLAKASPNAIVVMVSNPVD 122
>UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=2;
Desulfitobacterium hafniense|Rep: Malate dehydrogenase,
NAD-dependent - Desulfitobacterium hafniense (strain
DCB-2)
Length = 320
Score = 53.6 bits (123), Expect = 3e-06
Identities = 22/54 (40%), Positives = 38/54 (70%)
Frame = +3
Query: 333 DADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
D+DVVVI G+ R+PGM+R++L + NA IV + + ++P + + I++NPV+
Sbjct: 71 DSDVVVITAGIARKPGMSRNELCDINAGIVTHVVRQVVQHSPNSTLIILSNPVD 124
>UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2;
Gammaproteobacteria|Rep: Lactate dehydrogenase -
Reinekea sp. MED297
Length = 319
Score = 53.6 bits (123), Expect = 3e-06
Identities = 33/83 (39%), Positives = 44/83 (53%), Gaps = 2/83 (2%)
Frame = +3
Query: 246 GVAADLSHVN--TPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASI 419
G D H N T +K + ++ S + DAD+VVI G + G TRDDL N+ I
Sbjct: 40 GEMMDFGHANSLTFSKNIRLRAGDDYSL-LTDADIVVITAGAQIKEGQTRDDLAEINSRI 98
Query: 420 VRDIALSIAXNAPKAIVAIITNP 488
DIA I AP AI+ ++TNP
Sbjct: 99 TVDIAQKIETVAPNAILLVVTNP 121
>UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacter
fetus subsp. fetus 82-40|Rep: Malate dehydrogenase -
Campylobacter fetus subsp. fetus (strain 82-40)
Length = 306
Score = 53.6 bits (123), Expect = 3e-06
Identities = 24/56 (42%), Positives = 37/56 (66%)
Frame = +3
Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+KD D+VVI G R+ G +RDDL NA IV + ++ APK+I+ ++TNP++
Sbjct: 67 LKDFDIVVITAGFARKDGQSRDDLAMMNAKIVSHSSKMVSKFAPKSIIIVVTNPLD 122
>UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium
(Plasmodium)|Rep: Lactate dehydrogenase - Plasmodium
vivax
Length = 299
Score = 53.6 bits (123), Expect = 3e-06
Identities = 43/127 (33%), Positives = 62/127 (48%), Gaps = 10/127 (7%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPA----KVSGHKGPEELSXA 326
IG +A L+ Q L + ++D+ P G A D SH N A KV+G ++L
Sbjct: 8 IGGVMATLIVQKNLGD-VVMFDVVKNMPQGKALDTSHSNVMAYSNCKVTGSNSYDDL--- 63
Query: 327 IKDADVVVIPXGVPREPGMT-----RDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPV 491
K ADVV++ G + PG + RDDL N I+ +I I P A + ++TNPV
Sbjct: 64 -KGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKNLCPNAFIIVVTNPV 122
Query: 492 NFYSALL 512
+ LL
Sbjct: 123 DVMVQLL 129
>UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11;
Clostridium|Rep: L-lactate dehydrogenase - Clostridium
perfringens
Length = 317
Score = 52.8 bits (121), Expect = 5e-06
Identities = 33/112 (29%), Positives = 54/112 (48%), Gaps = 1/112 (0%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
+G A L Q+ L + + + DI A DL+ K K + KD+
Sbjct: 17 VGSTTAFALMQDGLASEIVIVDINKDKAHAEAMDLAQGAAFVKSVDIKSGDYADT--KDS 74
Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
D+V+I GV +PG TR D+ N N I + I + +P +I+ +++NPV+
Sbjct: 75 DIVIITAGVGPKPGETRLDIINKNLKIFQSIVPEVVKYSPNSILLVVSNPVD 126
>UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12;
Firmicutes|Rep: L-lactate dehydrogenase 2 - Bacillus
anthracis
Length = 314
Score = 52.8 bits (121), Expect = 5e-06
Identities = 34/83 (40%), Positives = 41/83 (49%)
Frame = +3
Query: 246 GVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVR 425
G A DLSH P S K KDAD+VVI G+P++PG TR DL N I +
Sbjct: 45 GEAMDLSHA-VPFSPSPTKVWSGSYADCKDADLVVITAGLPQKPGETRLDLVEKNTKIFK 103
Query: 426 DIALSIAXNAPKAIVAIITNPVN 494
I I + I I TNPV+
Sbjct: 104 QIVRGIMDSGFDGIFLIATNPVD 126
>UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 312
Score = 52.4 bits (120), Expect = 6e-06
Identities = 25/55 (45%), Positives = 34/55 (61%)
Frame = +3
Query: 330 KDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
KDAD++VI GVPR PG TR D+ + + VRDI ++ K I+ ITNP +
Sbjct: 71 KDADIIVISAGVPRLPGQTRLDVLDGSVECVRDIVSNLNKIEIKGIIITITNPAD 125
>UniRef50_O26290 Cluster: Malate dehydrogenase; n=2;
Methanobacteriaceae|Rep: Malate dehydrogenase -
Methanobacterium thermoautotrophicum
Length = 325
Score = 52.4 bits (120), Expect = 6e-06
Identities = 26/51 (50%), Positives = 32/51 (62%)
Frame = +3
Query: 342 VVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+VVI GVPR M RDDL N IV D A IA AP +I+ ++TNPV+
Sbjct: 75 IVVITAGVPRTADMDRDDLAFKNGRIVADYARQIARFAPDSIILVVTNPVD 125
>UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2;
Ruminococcus|Rep: Putative uncharacterized protein -
Ruminococcus torques ATCC 27756
Length = 316
Score = 52.0 bits (119), Expect = 8e-06
Identities = 38/113 (33%), Positives = 56/113 (49%), Gaps = 2/113 (1%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSH-VNTPAKVSGHKGPEELSXAIKD 335
+G +A L Q L + + L D G A D+SH + + + G E I D
Sbjct: 15 VGSTIAYTLMQKGLFSEMVLLDANKAKAEGEAMDISHGLPFTHAMDIYAGEYE---DIAD 71
Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
A VV+I G ++PG TR DL NA+I+R I I + I+ I++NPV+
Sbjct: 72 ASVVIITAGANQKPGETRLDLVQKNAAIMRSIIKEIKRVNCEGILLIVSNPVD 124
>UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3;
Methanomicrobiales|Rep: L-lactate dehydrogenase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 319
Score = 52.0 bits (119), Expect = 8e-06
Identities = 38/123 (30%), Positives = 62/123 (50%), Gaps = 7/123 (5%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIA---PVTPGVAADLSHV----NTPAKVSGHKGPEELS 320
+G +A + Q P V + LY G+A D+ T +V+ P+EL
Sbjct: 13 VGSYVAHAVSQFPHVQEMCLYGRPGNEQYLDGLAHDMMDSFAARGTNTRVTFGTTPKEL- 71
Query: 321 XAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFY 500
+ +D++V+ GVPR+ TR DL NA IV+ A + AP+AI+ ++TNPV+
Sbjct: 72 ---RGSDIIVLTSGVPRKATQTRLDLALENARIVKVFAEQVGRMAPEAILLVVTNPVDIM 128
Query: 501 SAL 509
+ +
Sbjct: 129 TTV 131
>UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17;
Bacteria|Rep: L-lactate dehydrogenase 2 -
Bifidobacterium longum
Length = 320
Score = 52.0 bits (119), Expect = 8e-06
Identities = 35/115 (30%), Positives = 55/115 (47%), Gaps = 4/115 (3%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHVNT---PAKVSGHKGPEELSXAI 329
+G LA Q + + L DIA D+ H ++ + G PE
Sbjct: 19 VGSTLAFAAAQRGIAREIVLEDIAKERVEAEVLDMQHGSSFYPTVSIDGSDDPE----IC 74
Query: 330 KDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+DAD+VVI G ++PG +R +L +I++ I ++ AP AI +ITNPV+
Sbjct: 75 RDADMVVITAGPRQKPGQSRLELVGATVNILKAIMPNLVKVAPNAIYMLITNPVD 129
>UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140;
Bacteria|Rep: L-lactate dehydrogenase - Streptococcus
pneumoniae
Length = 328
Score = 50.8 bits (116), Expect = 2e-05
Identities = 38/133 (28%), Positives = 57/133 (42%), Gaps = 6/133 (4%)
Frame = +3
Query: 114 TSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPV---TPGVAADLSHV---N 275
TS + K +G A L + L + +I + G A DLSH
Sbjct: 2 TSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLHEKAVGDALDLSHALAFT 61
Query: 276 TPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNA 455
+P K+ + + DAD+VVI G P++PG TR DL N +I + I + +
Sbjct: 62 SPKKIYAAQYSD-----CADADLVVITAGAPQKPGETRLDLVGKNLAINKSIVTQVVESG 116
Query: 456 PKAIVAIITNPVN 494
K I + NPV+
Sbjct: 117 FKGIFLVAANPVD 129
>UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasma
hyopneumoniae|Rep: L-lactate dehydrogenase - Mycoplasma
hyopneumoniae
Length = 315
Score = 50.8 bits (116), Expect = 2e-05
Identities = 24/56 (42%), Positives = 35/56 (62%)
Frame = +3
Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+KDAD +VI G P++PG TR +L N I+R+IAL + + I I+ NPV+
Sbjct: 69 LKDADFIVITAGRPQKPGETRLELVADNIRIIREIALKVKESGFSGISIIVANPVD 124
>UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex
aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus
Length = 334
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/69 (34%), Positives = 40/69 (57%)
Frame = +3
Query: 288 VSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAI 467
V G +E +K +D+VVI G+PR GM+R+DL N I++ +I A +I
Sbjct: 73 VKGISYDKEGFEELKGSDIVVITAGIPRREGMSREDLLYENLKILKKFTDAIKEYAKDSI 132
Query: 468 VAIITNPVN 494
+ +++NPV+
Sbjct: 133 IIVVSNPVD 141
>UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2;
Bacteria|Rep: L-lactate dehydrogenase - Treponema
denticola
Length = 315
Score = 50.4 bits (115), Expect = 3e-05
Identities = 36/113 (31%), Positives = 57/113 (50%), Gaps = 2/113 (1%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSH-VNTPAKVSGHKGPEELSXAIKD 335
+G A L Q+ +A+ D+ G A DL + +V H G ++ A D
Sbjct: 16 VGSTFAYALAQSGYADEIAITDMNKNFAEGQALDLVQGLPFLPQVDIHAG-DKTDYA--D 72
Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+D+VV+ G ++ G TR DL NASI+ IA IA + ++ I++NPV+
Sbjct: 73 SDIVVVTAGAKQQSGETRIDLLKRNASIITGIAKDIAESGCSGVMLIVSNPVD 125
>UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular
organisms|Rep: Malate dehydrogenase - Dehalococcoides
sp. (strain CBDB1)
Length = 307
Score = 49.6 bits (113), Expect = 4e-05
Identities = 19/53 (35%), Positives = 36/53 (67%)
Frame = +3
Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+++VVI G+ R+PGMTR++L N I+ D+ + +P+A + +++NPV+
Sbjct: 70 SEIVVITAGIARKPGMTREELLAINQKIMTDVVSNCLKYSPEATLVVVSNPVD 122
>UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7;
Bacteria|Rep: L-lactate dehydrogenase - Deinococcus
radiodurans
Length = 304
Score = 49.2 bits (112), Expect = 6e-05
Identities = 26/71 (36%), Positives = 40/71 (56%)
Frame = +3
Query: 297 HKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAI 476
H G EL+ DA VV++ G ++PG +R DL NA I R++ I AP A++ +
Sbjct: 59 HGGHSELA----DAQVVILTAGANQKPGESRLDLLEKNADIFRELVPQITRAAPDAVLLV 114
Query: 477 ITNPVNFYSAL 509
+NPV+ + L
Sbjct: 115 TSNPVDLLTDL 125
>UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7;
Halobacteriaceae|Rep: Malate dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 304
Score = 48.4 bits (110), Expect = 1e-04
Identities = 32/86 (37%), Positives = 45/86 (52%), Gaps = 1/86 (1%)
Frame = +3
Query: 240 TPGVAADLSH-VNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNAS 416
T G AAD +H + + +G E + +DVVVI G+PR+PG TR DL NA
Sbjct: 42 TVGQAADTNHGIAYDSNTRVRQGGYEDTAG---SDVVVITAGIPRQPGQTRIDLAGDNAP 98
Query: 417 IVRDIALSIAXNAPKAIVAIITNPVN 494
I+ DI S+ + I +NPV+
Sbjct: 99 IMEDIQSSLDEHNDDYISLTTSNPVD 124
>UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2;
Ascomycota|Rep: Probable L-lactate dehydrogenase -
Schizosaccharomyces pombe (Fission yeast)
Length = 330
Score = 48.4 bits (110), Expect = 1e-04
Identities = 45/141 (31%), Positives = 63/141 (44%), Gaps = 7/141 (4%)
Frame = +3
Query: 93 GAKNFSTTSQRN--FKXXXXXXXXX--IGQPLALLLKQNPLVTRLALYDI-APVTPGVAA 257
G+K FS S R+ FK +G A L + L + + D+ G A
Sbjct: 4 GSKVFSNDSVRSSSFKSIKIVIVGAGNVGSTTAFTLLLSGLAAEIVIIDLNKKKAEGEAM 63
Query: 258 DLSHVNTPAKVSGHKGPEELSXA--IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDI 431
DL+H A +S H+ L KDA VVI G ++PG TR DL N SI ++I
Sbjct: 64 DLNHA---APLS-HETRVYLGDYKDCKDATAVVITAGKNQKPGETRMDLLKANISIFKEI 119
Query: 432 ALSIAXNAPKAIVAIITNPVN 494
+ AI+ + TNPV+
Sbjct: 120 LREVTKYTKDAILLVATNPVD 140
>UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
mobile|Rep: L-lactate dehydrogenase - Mycoplasma mobile
Length = 318
Score = 48.4 bits (110), Expect = 1e-04
Identities = 23/56 (41%), Positives = 36/56 (64%)
Frame = +3
Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+KD DVVVI G P++PG TR ++ NA I+ +IA +I + K + ++ NPV+
Sbjct: 71 LKDYDVVVITAGRPQKPGETRLEMVADNAKIMSNIAKNIKKSGFKGVSIVVANPVD 126
>UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula
stellata E-37|Rep: L-lactate dehydrogenase - Sagittula
stellata E-37
Length = 300
Score = 48.0 bits (109), Expect = 1e-04
Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 4/115 (3%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPV-TPGVAADLSHVNTPAKVSGH---KGPEELSXAI 329
+G A + + + L D+ A D++H P VS G ++LS A
Sbjct: 2 VGSAAAFACIMRGVASEIVLVDLDTARAQAEAEDIAHA-VPFSVSARIVAGGYDDLSGA- 59
Query: 330 KDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
DVV++ GV ++PG +R +L + NA + R + + AP AI+ I +NPV+
Sbjct: 60 ---DVVILACGVSQKPGESRLELLSRNAEVFRAVVGDVTRAAPDAILLIASNPVD 111
>UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;
Clostridium|Rep: L-lactate dehydrogenase precursor -
Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
Length = 318
Score = 48.0 bits (109), Expect = 1e-04
Identities = 30/119 (25%), Positives = 56/119 (47%), Gaps = 2/119 (1%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSH-VNTPAKVSGHKGPEELSXAIKD 335
+G A + L L D+ G A D++H + ++S + G +KD
Sbjct: 18 VGASAAFTMALRQTANELVLIDVFKEKAIGEAMDINHGLPFMGQMSLYAGDYS---DVKD 74
Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSALL 512
DV+V+ G R+PG TR DL N I +++ +I ++ +++NPV+ + ++
Sbjct: 75 CDVIVVTAGANRKPGETRLDLAKKNVMIAKEVTQNIMKYYNHGVILVVSNPVDIITYMI 133
>UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4;
Bacteroidales|Rep: Malate dehydrogenase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 334
Score = 47.6 bits (108), Expect = 2e-04
Identities = 36/113 (31%), Positives = 47/113 (41%), Gaps = 2/113 (1%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYD-IAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
IG +A L L LYD A GVA ++ H ++ A+ DA
Sbjct: 18 IGSNMAQTAAMMRLTPNLCLYDPFAVGLEGVAEEIRHCGFEGL--NLTFTSDIKEALTDA 75
Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKA-IVAIITNPVN 494
+V G PR+ GMTR+DL NA I + I P V II NP +
Sbjct: 76 KYIVSSGGAPRKEGMTREDLLKGNAEIAAQLGKDIKSYCPDCKHVIIIFNPAD 128
>UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;
Candidatus Methanoregula boonei 6A8|Rep: L-lactate
dehydrogenase precursor - Methanoregula boonei (strain
6A8)
Length = 332
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/56 (41%), Positives = 33/56 (58%)
Frame = +3
Query: 327 IKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+ +D+VVI G PR PG R DL NA I+ +A +I AP + ++TNPV+
Sbjct: 71 VAGSDIVVITAGTPRGPGQNRLDLALGNARIIAPMARTIGTIAPDTKIIMVTNPVD 126
>UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia
burgdorferi group|Rep: L-lactate dehydrogenase -
Borrelia burgdorferi (Lyme disease spirochete)
Length = 316
Score = 46.8 bits (106), Expect = 3e-04
Identities = 37/116 (31%), Positives = 54/116 (46%), Gaps = 5/116 (4%)
Frame = +3
Query: 162 IGQPLALLLK-QNPLVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHKGPEELSXAIKD 335
+G A L N LV L + D+ G DL+H K K L KD
Sbjct: 15 VGSSFAYALTIDNSLVHELVIIDVNENKAKGEVMDLNHGQMFLK----KNINVLFGTYKD 70
Query: 336 ---ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
AD+VVI G+ ++PG TR DL + N+ I +DI ++ + I + +NPV+
Sbjct: 71 CANADIVVITAGLNQKPGETRLDLVDKNSKIFKDIITNVVSSGFDGIFVVASNPVD 126
>UniRef50_Q86DP2 Cluster: Malate dehydrogenase; n=11; Fungi/Metazoa
group|Rep: Malate dehydrogenase - Plicopurpura patula
Length = 229
Score = 46.4 bits (105), Expect = 4e-04
Identities = 22/34 (64%), Positives = 25/34 (73%)
Frame = +3
Query: 393 DLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
DLFNTNA IVRD+ IA P A++ IITNPVN
Sbjct: 1 DLFNTNAGIVRDLTDRIAKVCPTAMLGIITNPVN 34
>UniRef50_Q017A6 Cluster: Malate dehydrogenase; n=2; cellular
organisms|Rep: Malate dehydrogenase - Ostreococcus tauri
Length = 477
Score = 46.0 bits (104), Expect = 5e-04
Identities = 20/38 (52%), Positives = 27/38 (71%)
Frame = +3
Query: 381 MTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
MTRDDLF N IV+ + +IA N P A++ +I+NPVN
Sbjct: 1 MTRDDLFAINGGIVKGLVEAIADNCPNAMINMISNPVN 38
>UniRef50_UPI00015B5ACF Cluster: PREDICTED: similar to
ENSANGP00000020184; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000020184 - Nasonia
vitripennis
Length = 352
Score = 45.6 bits (103), Expect = 7e-04
Identities = 35/130 (26%), Positives = 59/130 (45%), Gaps = 1/130 (0%)
Frame = +3
Query: 108 STTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAK 287
++++ RN K G+ LAL LKQ+ L+ LA+YD P T G+ +LSH+++ +
Sbjct: 29 TSSNSRNLKVAIVGATGQTGRSLALCLKQSALIDELAVYDSHP-TRGLLLELSHMDSRCR 87
Query: 288 VSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRD-DLFNTNASIVRDIALSIAXNAPKA 464
S D+ G + +T D + A + I + PKA
Sbjct: 88 TIVEDEASTTSACNGKRDLERALTGA-KIVAITLDGESIREEAEYLEKILSGLLGCCPKA 146
Query: 465 IVAIITNPVN 494
+VA+++ VN
Sbjct: 147 LVALVSRRVN 156
>UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6;
Bacteria|Rep: L-lactate dehydrogenase - Acidobacteria
bacterium (strain Ellin345)
Length = 321
Score = 45.6 bits (103), Expect = 7e-04
Identities = 34/115 (29%), Positives = 49/115 (42%), Gaps = 1/115 (0%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIA-PVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
+G A L Q L + L D G A DL+H P + E + + A
Sbjct: 21 VGASFAFALLQRRLAAEIVLIDANHKKAEGEAMDLNHA-VPFGAATRIWAGEYADC-RGA 78
Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYS 503
V VI G + PG TR L + N +I + I + + P ++ I TNPV+ S
Sbjct: 79 AVTVITAGAAQRPGETRLQLLDRNLAIFQQIVPEVVKHNPDGLLLIATNPVDIIS 133
>UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;
Clostridium phytofermentans ISDg|Rep: L-lactate
dehydrogenase precursor - Clostridium phytofermentans
ISDg
Length = 325
Score = 45.6 bits (103), Expect = 7e-04
Identities = 22/55 (40%), Positives = 31/55 (56%)
Frame = +3
Query: 330 KDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
KDAD+VVI G P +PG +R D +A IV I + + I ++TNPV+
Sbjct: 74 KDADIVVITAGPPPKPGQSRLDTLGLSADIVSTIVEPVMKSGFNGIFLVVTNPVD 128
>UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5;
Bacillaceae|Rep: L-lactate dehydrogenase -
Oceanobacillus iheyensis
Length = 321
Score = 45.6 bits (103), Expect = 7e-04
Identities = 37/128 (28%), Positives = 52/128 (40%), Gaps = 1/128 (0%)
Frame = +3
Query: 114 TSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKV 290
TSQ+ +G A L + LA+ D+ A G DL+H A
Sbjct: 3 TSQQAVNRVVLIGGGSVGVSYAFALMNQGVTEELAIIDLDADKALGDVMDLNHGKAFAPS 62
Query: 291 SGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIV 470
+ E KDAD+V I G ++ G TR DL N I ++I + + I
Sbjct: 63 LTNVWLGEYGDC-KDADIVCICAGANQQSGETRLDLVEKNMKIFKEIVTDVMNSGFNGIF 121
Query: 471 AIITNPVN 494
I TNPV+
Sbjct: 122 LIATNPVD 129
>UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
pulmonis|Rep: L-lactate dehydrogenase - Mycoplasma
pulmonis
Length = 315
Score = 45.6 bits (103), Expect = 7e-04
Identities = 25/88 (28%), Positives = 44/88 (50%)
Frame = +3
Query: 246 GVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVR 425
G A D+S +G K K AD++++ G P++ G TR ++ N+ I++
Sbjct: 41 GHAMDMSDAIALNSTTGSKIRTGTYADAKGADLLIVAAGRPQKQGETRLEMIADNSKIMK 100
Query: 426 DIALSIAXNAPKAIVAIITNPVNFYSAL 509
DIAL I + +I+NPV+ + +
Sbjct: 101 DIALEIKKSGFNGFTIVISNPVDILATV 128
>UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9;
Bacilli|Rep: L-lactate dehydrogenase 2 - Enterococcus
faecalis (Streptococcus faecalis)
Length = 317
Score = 45.6 bits (103), Expect = 7e-04
Identities = 22/55 (40%), Positives = 35/55 (63%)
Frame = +3
Query: 330 KDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+DAD+VVI G ++PG +R DL + NA I++ I +I + I+ I +NPV+
Sbjct: 72 QDADIVVITAGANQKPGQSRLDLVSINAEIMKTIVNNIMKSGFDGILVIASNPVD 126
>UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5;
Bacteroidales|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 333
Score = 45.2 bits (102), Expect = 0.001
Identities = 34/121 (28%), Positives = 49/121 (40%), Gaps = 2/121 (1%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYD-IAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
IG +A L + LYD AP GVA +L H + ++ A+ A
Sbjct: 18 IGSNMAQTALMMKLTPNICLYDPYAPALEGVAEELYHCAFEGVNLTYTS--DIKEALSGA 75
Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKA-IVAIITNPVNFYSALLP 515
+V G R+ GMTR+DL NA I I P V ++ NP + ++
Sbjct: 76 KYIVSSGGAARKAGMTREDLLKGNAEIAAQFGKDIRQYCPDVKHVVVVFNPADITGLIVL 135
Query: 516 L 518
L
Sbjct: 136 L 136
>UniRef50_UPI00015B4591 Cluster: PREDICTED: similar to mitochondrial
malate dehydrogenase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to mitochondrial malate dehydrogenase
- Nasonia vitripennis
Length = 299
Score = 44.8 bits (101), Expect = 0.001
Identities = 30/114 (26%), Positives = 54/114 (47%), Gaps = 1/114 (0%)
Frame = +3
Query: 180 LLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPX 359
+LLKQNP + + L D D+ H++T + H + +++ D+V +
Sbjct: 1 MLLKQNPAIKEIRLIDTDNSLMSPVCDMRHIDTSTTIR-HFRKNSILDGLRNTDIVALMD 59
Query: 360 GVPREPGMTRDDL-FNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSALLPL 518
G + F +++ V+ +A + PKA+VA+ T+PV +A LPL
Sbjct: 60 ETDFMMGNKGPFMQFVNSSNYVKSVAECMINVCPKALVAVFTHPV---TATLPL 110
>UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:
Lactate dehydrogenase - Vibrio parahaemolyticus
Length = 317
Score = 44.8 bits (101), Expect = 0.001
Identities = 22/51 (43%), Positives = 31/51 (60%)
Frame = +3
Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNP 488
AD+VVI G + G TR D+ NA I +IA I APKA++ +++NP
Sbjct: 71 ADIVVITAGAQIQQGQTRLDIAEINAKIGVEIARKIERVAPKAVLIVVSNP 121
>UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1;
Lactobacillus casei ATCC 334|Rep: L-lactate
dehydrogenase - Lactobacillus casei (strain ATCC 334)
Length = 312
Score = 44.4 bits (100), Expect = 0.002
Identities = 20/61 (32%), Positives = 36/61 (59%)
Frame = +3
Query: 330 KDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSAL 509
K AD++VI G+ ++PG TR L NA I+++I +I + + + +NPV+ + L
Sbjct: 70 KYADIIVITAGIAQKPGQTRLQLLAINAKIMKEITHNIMASGFNGFILVASNPVDVLAEL 129
Query: 510 L 512
+
Sbjct: 130 V 130
>UniRef50_A0D8T3 Cluster: Malate dehydrogenase; n=2; Paramecium
tetraurelia|Rep: Malate dehydrogenase - Paramecium
tetraurelia
Length = 322
Score = 44.4 bits (100), Expect = 0.002
Identities = 24/69 (34%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
Frame = +3
Query: 324 AIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAI-VAIITNPVNFY 500
A KDADV + +PR+PGM R DL N I + A + V ++ NP N
Sbjct: 79 AFKDADVAIFLGAMPRKPGMERSDLLQMNREIFIQQGQILNEQAKSTVKVLVVANPSNTN 138
Query: 501 SALLPLKCS 527
A L +C+
Sbjct: 139 CATLAHQCT 147
>UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibacter
ruber DSM 13855|Rep: L-lactate dehydrogenase -
Salinibacter ruber (strain DSM 13855)
Length = 316
Score = 44.4 bits (100), Expect = 0.002
Identities = 21/58 (36%), Positives = 35/58 (60%), Gaps = 1/58 (1%)
Frame = +3
Query: 324 AIKDADVVVIPXGVPRE-PGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
A+ +A ++V+ G ++ P TR L NA I R+I + + +AP AI+ + TNPV+
Sbjct: 68 ALSNAQIIVLSAGASQQSPDETRLGLLQRNAEIFREIIIQLDKHAPNAILVVATNPVD 125
>UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: L-lactate dehydrogenase -
Clostridium beijerinckii NCIMB 8052
Length = 316
Score = 44.0 bits (99), Expect = 0.002
Identities = 36/117 (30%), Positives = 53/117 (45%), Gaps = 3/117 (2%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPGV-AADLSHV--NTPAKVSGHKGPEELSXAIK 332
+G +A + N + L L DI A DL H + +K+ G E
Sbjct: 16 VGAAVAFDMVMNHVCDDLILIDINKEKSWAEATDLQHSLGYSGSKMRVKDGEYE---ECN 72
Query: 333 DADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYS 503
DAD+VVI +P G TR D+ A I+ +I +I + I+ +ITNPV+ S
Sbjct: 73 DADIVVIAAALPYITGQTRLDMLEKAAGIMNNIVPNIMKSGFSGIIVVITNPVDVMS 129
>UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomonas
ruminantium|Rep: L-lactate dehydrogenase - Selenomonas
ruminantium
Length = 318
Score = 44.0 bits (99), Expect = 0.002
Identities = 35/117 (29%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNT---PAKVSGHKGPEELSXAI 329
+G +A + L T + L D+ G A D SH + + H G E
Sbjct: 15 VGSAVANKIADFQLATEVVLIDLNEDKAWGEAKDSSHATSCIYSTNIKFHLGDYE---DC 71
Query: 330 KDADVVVIPXGVPREPGMTRD--DLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
KDA+++VI G PG T D L TNA I+ + I +A++ +ITNP++
Sbjct: 72 KDANIIVITAGPSIRPGETPDRLKLAGTNAKIMSSVMGEIVKRTKEAMIIMITNPLD 128
>UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6;
Mollicutes|Rep: L-lactate dehydrogenase - Mesoplasma
florum (Acholeplasma florum)
Length = 317
Score = 44.0 bits (99), Expect = 0.002
Identities = 21/53 (39%), Positives = 32/53 (60%)
Frame = +3
Query: 330 KDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNP 488
KDAD++VI G P+ PG TR +L N+ I++ IA +I + + I +NP
Sbjct: 72 KDADLIVITAGRPQRPGETRLELIADNSRIMKGIAEAIKASGFNGVTVIASNP 124
>UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14;
Bacillales|Rep: L-lactate dehydrogenase X - Bacillus
psychrosaccharolyticus
Length = 319
Score = 44.0 bits (99), Expect = 0.002
Identities = 35/128 (27%), Positives = 51/128 (39%), Gaps = 3/128 (2%)
Frame = +3
Query: 120 QRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSH--VNTPAKV 290
QRN +G A L + L + D+ G A DL+H + P
Sbjct: 3 QRNINRVALIGAGSVGSSYAFALLNQSITEELVIIDVNEDKAMGDAMDLNHGKIFAPNPT 62
Query: 291 SGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIV 470
G + K+AD+V I G ++PG TR DL N I + + + + I
Sbjct: 63 KTWYGNYD---DCKEADIVCICAGANQKPGETRLDLVEKNLKIFKSLVDQVMASGFDGIF 119
Query: 471 AIITNPVN 494
I TNPV+
Sbjct: 120 LIATNPVD 127
>UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Mycobacterium sp. (strain KMS)
Length = 329
Score = 43.6 bits (98), Expect = 0.003
Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 2/96 (2%)
Frame = +3
Query: 213 LALYDI--APVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMT 386
LALYD A V V DL+H + G ++++ A +VV+ G + PG +
Sbjct: 46 LALYDTNSAKVRAEVL-DLNHGSQFVPECRVGGSDDIAVTAGSA-IVVVTAGAKQHPGQS 103
Query: 387 RDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
R DL N ++ + + + ++P A+V +TNPV+
Sbjct: 104 RLDLAAANVAMAQTLTPQLLEHSPDAVVIFVTNPVD 139
>UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Lactate/malate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 303
Score = 43.6 bits (98), Expect = 0.003
Identities = 19/58 (32%), Positives = 34/58 (58%)
Frame = +3
Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSAL 509
AD+VVI G+PR+ R L + NA+++ D+ +P I+ ++TNP++ + L
Sbjct: 68 ADIVVITAGIPRKADEPRVLLLSRNAALIADLVRQAVHYSPNCIIFMVTNPLDVMTQL 125
>UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12;
Campylobacter|Rep: Probable malate dehydrogenase -
Campylobacter jejuni
Length = 300
Score = 43.6 bits (98), Expect = 0.003
Identities = 20/56 (35%), Positives = 32/56 (57%)
Frame = +3
Query: 330 KDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNF 497
K++D+V+ G R+ G +R++L N SI+ D A I + I+TNPV+F
Sbjct: 68 KNSDIVLFSAGFARKDGQSREELLQLNTSIMLDCAKKIKDFTEDPLFIILTNPVDF 123
>UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate
dehydrogenases; n=2; Nostoc punctiforme PCC 73102|Rep:
COG0039: Malate/lactate dehydrogenases - Nostoc
punctiforme PCC 73102
Length = 317
Score = 42.7 bits (96), Expect = 0.005
Identities = 22/57 (38%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Frame = +3
Query: 327 IKDADVVVI-PXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
+ D+D+++I GV + G TR D + NA I+R + AP +IV II+NPV+
Sbjct: 71 LADSDIIIIVTAGVQPKLGQTRLDTLSDNAEIIRSTIKELDRVAPNSIVIIISNPVD 127
>UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4;
Bacteria|Rep: L-lactate dehydrogenase - Blastopirellula
marina DSM 3645
Length = 313
Score = 42.7 bits (96), Expect = 0.005
Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 3/119 (2%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
+G A L+ + +AL D+ A + G A DL H P+ V+ I D+
Sbjct: 12 VGSCAAFALQCGGIAREIALLDLNADLAGGHALDLLH-GAPS-VADQVITSGGYEHIPDS 69
Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPK--AIVAIITNPVNFYSAL 509
DV+ I G+ R+P +R DL N N + I S+ K AI +++NPV+ + L
Sbjct: 70 DVICITAGLRRKPDESRLDLINRNVDLFLSILDSVKSAGVKKDAICFVVSNPVDILTYL 128
>UniRef50_Q23CW4 Cluster: Malate dehydrogenase, cytoplasmic,
putative; n=3; Oligohymenophorea|Rep: Malate
dehydrogenase, cytoplasmic, putative - Tetrahymena
thermophila SB210
Length = 365
Score = 42.7 bits (96), Expect = 0.005
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Frame = +3
Query: 237 VTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNAS 416
+ GV +L P S G E S +D DV V G PR+PGM R DL N +
Sbjct: 89 ILQGVELELQDGAYPLLKSIKTGSNE-SILFQDVDVAVFIGGFPRKPGMERKDLLTINGN 147
Query: 417 IVRDIALSIAXNAPKAIVA-IITNPVN 494
I + ++ A K + ++ NP N
Sbjct: 148 IFKKQGQALDTVAKKTCKSLVVANPAN 174
>UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1;
Methanoculleus marisnigri JR1|Rep: Lactate/malate
dehydrogenase - Methanoculleus marisnigri (strain ATCC
35101 / DSM 1498 / JR1)
Length = 288
Score = 42.3 bits (95), Expect = 0.007
Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 2/113 (1%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
+G A L LV + +YD+ P+ DL H +S + A++DA
Sbjct: 12 VGGETAFLSAALGLVDEIVVYDVYEPLLRAQVLDLQHTGIDVAISTE------TAAMRDA 65
Query: 339 DVVVIPXGVPREPGM-TRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
D+ V G PR P + TR DL N + + + + P +++ +TNP++
Sbjct: 66 DIFVFAAGTPRTPDIKTRADLLEANIPVAKRCS-ELLEGFPGVVIS-VTNPMD 116
>UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2;
Desulfovibrio vulgaris subsp. vulgaris|Rep: L-lactate
dehydrogenase - Desulfovibrio vulgaris (strain
Hildenborough / ATCC 29579 / NCIMB8303)
Length = 309
Score = 41.5 bits (93), Expect = 0.012
Identities = 20/53 (37%), Positives = 29/53 (54%)
Frame = +3
Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
A +VV+ G + PG +R DL NA I RDI ++ A + + TNPV+
Sbjct: 69 ARIVVVTAGAKQMPGQSRLDLVRVNAGITRDILTAVMQYADDPLYIMATNPVD 121
>UniRef50_P61973 Cluster: Malate dehydrogenase; n=43; Bacteria|Rep:
Malate dehydrogenase - Bdellovibrio bacteriovorus
Length = 335
Score = 40.7 bits (91), Expect = 0.020
Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Frame = +3
Query: 324 AIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNA-PKAIVAIITNPVN 494
A KDADV ++ PR PGM R DL N I +I A P V ++ NP N
Sbjct: 79 AFKDADVALLVGARPRGPGMERKDLLTANGQIFTVQGEAIGKYANPNVKVLVVGNPAN 136
>UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;
Theileria|Rep: L-lactate dehydrogenase, putative -
Theileria annulata
Length = 367
Score = 40.3 bits (90), Expect = 0.027
Identities = 17/36 (47%), Positives = 25/36 (69%)
Frame = +3
Query: 387 RDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
RDDL N+ I+RD+ +I AP+A V +ITNP++
Sbjct: 143 RDDLVGYNSKIIRDVGENIKKYAPEAFVIVITNPMD 178
>UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13;
Firmicutes|Rep: L-lactate dehydrogenase 3 - Bacillus
anthracis
Length = 316
Score = 40.3 bits (90), Expect = 0.027
Identities = 32/114 (28%), Positives = 50/114 (43%), Gaps = 3/114 (2%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSH-VN-TPAKVSGHKGPEELSXAIK 332
+G A + + L L DI G A DLSH +N T + + G E K
Sbjct: 16 VGSSCAYSIVNQGICEELLLIDINHERAVGEAMDLSHCINFTNTRTKVYAGSYE---DCK 72
Query: 333 DADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
D D+V+I G +PG +R D +A I+ + + + I + +NPV+
Sbjct: 73 DMDIVIITAGPAPKPGQSRLDTLGASAKIMESVVGGVMESGFDGIFLLASNPVD 126
>UniRef50_Q9GPV2 Cluster: Cytosolic malate dehydrogenase; n=4;
Trichomonadida|Rep: Cytosolic malate dehydrogenase -
Tetratrichomonas gallinarum
Length = 314
Score = 39.1 bits (87), Expect = 0.062
Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Frame = +3
Query: 288 VSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAI 467
V+G +++ A KD DV + PR+ GM R DL N I +++ A K +
Sbjct: 46 VAGIVWTDKIEEAFKDVDVAFLVGSFPRKDGMDRSDLLAKNGGIFTVQGKALSDFAKKDV 105
Query: 468 -VAIITNPVN 494
V ++ NP N
Sbjct: 106 KVLVVGNPAN 115
>UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1;
Corynebacterium jeikeium K411|Rep: L-lactate
dehydrogenase - Corynebacterium jeikeium (strain K411)
Length = 326
Score = 38.3 bits (85), Expect = 0.11
Identities = 32/115 (27%), Positives = 48/115 (41%), Gaps = 1/115 (0%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
+G A L L LA+ D+ T G DL+H P + +DA
Sbjct: 26 VGIAYAYTLVNQGLTDHLAIIDLDERKTWGHVQDLNHA-VPWSHHNTRVTVGTYEDCRDA 84
Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYS 503
+V I G ++PG TR DL N +I + I + + I + +NPV+ S
Sbjct: 85 AMVCICAGAAQKPGETRLDLVAKNTAIFKTIVGDVMSHGFNGIFLVASNPVDILS 139
>UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizopus
oryzae|Rep: L-lactate dehydrogenase A - Rhizopus oryzae
(Rhizopus delemar)
Length = 320
Score = 38.3 bits (85), Expect = 0.11
Identities = 26/112 (23%), Positives = 47/112 (41%), Gaps = 1/112 (0%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
+G A L + T + + D+ P + DL+ + + G E + A
Sbjct: 15 VGASTAYALMFKNICTEIIIVDVNPDIVQAQVLDLADAASISHTPIRAGSAEEAG---QA 71
Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
D+VVI G + G R L N +++ I + P A++ ++ NPV+
Sbjct: 72 DIVVITAGAKQREGEPRTKLIERNFRVLQSIIGGMQPIRPDAVILVVANPVD 123
>UniRef50_Q017A7 Cluster: Chromosome 06 contig 1, DNA sequence; n=1;
Ostreococcus tauri|Rep: Chromosome 06 contig 1, DNA
sequence - Ostreococcus tauri
Length = 131
Score = 37.9 bits (84), Expect = 0.14
Identities = 18/31 (58%), Positives = 20/31 (64%)
Frame = -1
Query: 334 SLMAXDSSSGPLWPLTLAGVFTWERSAATPG 242
S A SS+ P +P T A VFT E SAATPG
Sbjct: 7 SFSAAPSSASPAYPFTCAAVFTCETSAATPG 37
>UniRef50_Q7QQW5 Cluster: Malate dehydrogenase; n=2; Giardia
intestinalis|Rep: Malate dehydrogenase - Giardia lamblia
ATCC 50803
Length = 331
Score = 37.9 bits (84), Expect = 0.14
Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
Frame = +3
Query: 246 GVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVR 425
GVA +L P +SG + + A KD D ++ PR+ GM R +L + N I +
Sbjct: 53 GVAMELVDCAFPL-LSGFTLTSDNAEAFKDVDYCLLFGAFPRKAGMERAELLSKNKGIFQ 111
Query: 426 DIALSIAXNA-PKAIVAIITNPVNFYSALL 512
+I +A P + +I NP N + +L
Sbjct: 112 IQGAAINEHAKPTCRILVIGNPANTNALVL 141
>UniRef50_P83778 Cluster: Malate dehydrogenase, cytoplasmic; n=1;
Candida albicans|Rep: Malate dehydrogenase, cytoplasmic
- Candida albicans (Yeast)
Length = 51
Score = 33.5 bits (73), Expect(2) = 0.18
Identities = 19/29 (65%), Positives = 21/29 (72%)
Frame = +3
Query: 204 VTRLALYDIAPVTPGVAADLSHVNTPAKV 290
VT LALYDI P GVAAD+SHV T + V
Sbjct: 1 VTDLALYDIRP---GVAADVSHVPTNSTV 26
Score = 23.4 bits (48), Expect(2) = 0.18
Identities = 10/10 (100%), Positives = 10/10 (100%)
Frame = +3
Query: 396 LFNTNASIVR 425
LFNTNASIVR
Sbjct: 28 LFNTNASIVR 37
>UniRef50_A1W9K7 Cluster: Malate dehydrogenase; n=95; cellular
organisms|Rep: Malate dehydrogenase - Acidovorax sp.
(strain JS42)
Length = 328
Score = 37.1 bits (82), Expect = 0.25
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 1/84 (1%)
Frame = +3
Query: 246 GVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVR 425
GV +L P ++G + + A KD D ++ PR PGM R DL NA I
Sbjct: 55 GVIMELEDCAFPL-LAGIEAHSDPMTAFKDTDYALLVGARPRGPGMERADLLAANAQIFT 113
Query: 426 DIALSIAXNAPKAI-VAIITNPVN 494
++ A + + V ++ NP N
Sbjct: 114 AQGKALNAVASRNVKVLVVGNPAN 137
>UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate
dehydrogenase A chain (LDH-A) (LDH muscle subunit)
(LDH-M); n=2; Apis mellifera|Rep: PREDICTED: similar to
L-lactate dehydrogenase A chain (LDH-A) (LDH muscle
subunit) (LDH-M) - Apis mellifera
Length = 348
Score = 36.3 bits (80), Expect = 0.44
Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 1/111 (0%)
Frame = +3
Query: 174 LALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVV 350
+A+L K+ L + L D+ + A D+SH G ++ S A +DA V V
Sbjct: 49 IAILFKR--LASELVFIDVNEELAKAEAEDISHGAAFLGNPKIIGTKDYSLA-RDATVCV 105
Query: 351 IPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYS 503
I G L N +I +D+ + AP +I+ I+T PV+ S
Sbjct: 106 ITIGDRSTNEQDPSTLLEQNLNIFKDVIPKVCKYAPNSILLIVTAPVDILS 156
>UniRef50_UPI0000D8BD94 Cluster: UPI0000D8BD94 related cluster; n=2;
Danio rerio|Rep: UPI0000D8BD94 UniRef100 entry - Danio
rerio
Length = 732
Score = 35.9 bits (79), Expect = 0.58
Identities = 30/115 (26%), Positives = 49/115 (42%), Gaps = 4/115 (3%)
Frame = +3
Query: 165 GQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHK---GPEELSXAIKD 335
G P A+LL NP T+L + P+ H N A+++GH + S +
Sbjct: 285 GMPNAVLLSSNPNQTQLNQLTLNPLQLN-----HHPNCSAQLTGHPLTLPRPKFSYMNTN 339
Query: 336 ADVVVIPXGVPREPGMTRDDLFN-TNASIVRDIALSIAXNAPKAIVAIITNPVNF 497
V+ G + + D FN TN ++ ++ I+ PK ++ PVNF
Sbjct: 340 GSAAVVFLGYTAMENLLKADFFNATNDTVNTMMSSVISVTLPKTTNTALSKPVNF 394
>UniRef50_UPI0001554DCB Cluster: PREDICTED: similar to Zinc finger
protein 160, partial; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to Zinc finger protein 160, partial -
Ornithorhynchus anatinus
Length = 912
Score = 35.5 bits (78), Expect = 0.76
Identities = 17/43 (39%), Positives = 21/43 (48%)
Frame = +2
Query: 176 GPSTEAESSGDQAGFIRHSACDPRRRSRPFPREHPSQGQRPQG 304
GP S G G +R+SA DP RRS P P +R +G
Sbjct: 143 GPGEPVRSGGAGEGAVRNSALDPTRRSHPSPIPPRGSRERDEG 185
>UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;
n=2; Bacteria|Rep: Lactate/malate dehydrogenase
precursor - Bacillus coagulans 36D1
Length = 327
Score = 35.5 bits (78), Expect = 0.76
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 5/59 (8%)
Frame = +3
Query: 333 DADVVVIPXG---VPREPGMTRD--DLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
DADV++ G +P E D L TNA++VR++ I +A++ ITNP++
Sbjct: 72 DADVIICAAGPSVLPSEKDEMPDRAGLARTNAAVVREVMAGITKYTKEAVIIFITNPLD 130
>UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1;
Aspergillus niger|Rep: Catalytic activity: precursor -
Aspergillus niger
Length = 307
Score = 35.5 bits (78), Expect = 0.76
Identities = 20/58 (34%), Positives = 29/58 (50%)
Frame = +3
Query: 336 ADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSAL 509
ADVV+I GV PG T SI++ I + P AI+ ++ NPV+ + L
Sbjct: 70 ADVVIITAGVNYTPGETTLQHLYHKFSILKSILNEMRPFNPNAIILVVANPVDTLTTL 127
>UniRef50_A2E124 Cluster: Malate dehydrogenase; n=6;
Trichomonadidae|Rep: Malate dehydrogenase - Trichomonas
vaginalis G3
Length = 332
Score = 35.1 bits (77), Expect = 1.0
Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
Frame = +3
Query: 303 GPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNA-PKAIVAII 479
G +L A +D DV + P++P D F NASI + +++ A P V +I
Sbjct: 69 GTSDLEEAFRDVDVAFLVGSFPKKPSTKLVDYFQRNASIYSEHGRALSDFAKPTVKVLVI 128
Query: 480 TNPVN 494
P N
Sbjct: 129 GMPTN 133
>UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1;
Endoriftia persephone 'Hot96_1+Hot96_2'|Rep: Malate
dehydrogenase NAD-dependent - Endoriftia persephone
'Hot96_1+Hot96_2'
Length = 170
Score = 34.7 bits (76), Expect = 1.3
Identities = 13/35 (37%), Positives = 23/35 (65%)
Frame = +3
Query: 390 DDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
DDL + N S+ + +A ++ +AP A V + TNP++
Sbjct: 16 DDLLDINLSVTKKVATAVKQHAPDAFVILTTNPLD 50
>UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2;
Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
agalactiae
Length = 323
Score = 34.7 bits (76), Expect = 1.3
Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Frame = +3
Query: 306 PEELSXAIKDADVVVIPXGVPREPGMT-RDDLFNTNASIVRDIALSIAXNAPKAIVAIIT 482
P L KDADVVVI +P + + R L NA +++ A + K IV +
Sbjct: 62 PGTLLEDSKDADVVVITASIPADKTFSDRMALAGANAKLMQSFAKDLDAAGFKGIVVVAA 121
Query: 483 NPVNFYSA 506
NP + +A
Sbjct: 122 NPCDVMAA 129
>UniRef50_Q9Z6N1 Cluster: Malate dehydrogenase; n=8;
Chlamydiaceae|Rep: Malate dehydrogenase - Chlamydia
pneumoniae (Chlamydophila pneumoniae)
Length = 328
Score = 34.7 bits (76), Expect = 1.3
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
Frame = +3
Query: 315 LSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASI--VRDIALSIAXNAPKAIVAIITNP 488
L+ A D + VPR PGM R DL N I ++ AL+ A A + ++ NP
Sbjct: 76 LNDAFDGIDAAFLIGAVPRGPGMERGDLLKQNGQIFSLQGAALNTAAKR-DAKIFVVGNP 134
Query: 489 VN 494
VN
Sbjct: 135 VN 136
>UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1;
Clostridium acetobutylicum|Rep: L-lactate dehydrogenase
2 - Clostridium acetobutylicum
Length = 320
Score = 34.7 bits (76), Expect = 1.3
Identities = 28/101 (27%), Positives = 43/101 (42%), Gaps = 3/101 (2%)
Frame = +3
Query: 201 LVTRLALYDIAP-VTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREP 377
L++ + + DI G A D SH + A K DA ++VI G +P
Sbjct: 29 LLSEVVIIDINDNKAKGEALDASHTTSFAYSPNVKVRAGNYEDCADAQIIVITAGPSLKP 88
Query: 378 GMTRDDLF--NTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
D L +TN + I +I AI+ ++TNPV+
Sbjct: 89 DDKLDRLVLADTNVKVTDSIMKNICKYTKDAIIIVVTNPVD 129
>UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2;
Phaeosphaeria nodorum|Rep: L-lactate dehydrogenase -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 326
Score = 34.3 bits (75), Expect = 1.8
Identities = 29/112 (25%), Positives = 48/112 (42%), Gaps = 1/112 (0%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDI-APVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDA 338
+G LA L + T + L D + G DLS T G + + A
Sbjct: 18 VGATLAYTLILQSICTEVLLVDPKTSLLDGQVRDLSDA-TSRSTKVRSGTHQEAG---QA 73
Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
D+VVI G ++ G +R L N +I+ I S+ + ++ ++ NPV+
Sbjct: 74 DIVVITAGAKQKTGESRLSLLTRNLNILSSIFDSMKPISAHTVLLLVANPVD 125
>UniRef50_UPI0000DD82B5 Cluster: PREDICTED: hypothetical protein;
n=1; Homo sapiens|Rep: PREDICTED: hypothetical protein -
Homo sapiens
Length = 258
Score = 33.9 bits (74), Expect = 2.3
Identities = 20/41 (48%), Positives = 20/41 (48%), Gaps = 1/41 (2%)
Frame = +2
Query: 194 ESSGDQAGFIRHSACDPRRRSRPFPRE-HPSQGQRPQGT*G 313
E GDQ RH AC R S P E P GQRP GT G
Sbjct: 6 EGRGDQERTRRHRACPGCRGSEVSPGEGAPGSGQRPAGTSG 46
>UniRef50_Q4S3J0 Cluster: Chromosome 1 SCAF14749, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14749, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 778
Score = 33.5 bits (73), Expect = 3.1
Identities = 18/47 (38%), Positives = 21/47 (44%)
Frame = +2
Query: 137 GGRWCRRWYRPAFGPSTEAESSGDQAGFIRHSACDPRRRSRPFPREH 277
G R R + P GP E G Q +RH A P RR R P +H
Sbjct: 554 GVRAPRGLHHPGAGPQRAHEGRGRQPAAVRHPAEPPGRRHRERPGDH 600
>UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6;
Plasmodium|Rep: Oxidoreductase, putative - Plasmodium
falciparum (isolate 3D7)
Length = 334
Score = 33.5 bits (73), Expect = 3.1
Identities = 34/126 (26%), Positives = 61/126 (48%), Gaps = 9/126 (7%)
Frame = +3
Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTP-GVAADLSHVNTPAKVSGHK--GPEELSXAIK 332
IG LA ++ + L + L+D P G A D+ H P S G E++ IK
Sbjct: 17 IGCALAHMICEKNLGD-VVLHDFRKDLPKGRALDILHTR-PLNRSRINILGTNEITD-IK 73
Query: 333 DADVVVIPXGVPREPGMTRDD------LFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
D+ VVV+ V D+ ++ +N +++++A S+ + P+A V + T+PV+
Sbjct: 74 DSLVVVVTIEVSEREFAEFDEEDLEKQVYTSNVKLLKEVAKSLKKHCPQAFVVVTTSPVD 133
Query: 495 FYSALL 512
+ +L
Sbjct: 134 CMAKVL 139
>UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 237
Score = 33.1 bits (72), Expect = 4.1
Identities = 19/57 (33%), Positives = 27/57 (47%)
Frame = +3
Query: 339 DVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVNFYSAL 509
D+VVI G G T D N SIVR I + ++ I+ NPV+ ++L
Sbjct: 77 DIVVITAGSKYLYGQTSMDYLYRNTSIVRSIINEMKPFRSDTVLLIVANPVDLMTSL 133
>UniRef50_Q8NHM5 Cluster: JmjC domain-containing histone
demethylation protein 1B; n=56; Euteleostomi|Rep: JmjC
domain-containing histone demethylation protein 1B -
Homo sapiens (Human)
Length = 1336
Score = 32.7 bits (71), Expect = 5.4
Identities = 14/22 (63%), Positives = 16/22 (72%)
Frame = -2
Query: 144 RPPL*SSSVMWWKSSLHHFVQQ 79
RPPL SS WW+SSL +F QQ
Sbjct: 834 RPPLGSSLSPWWRSSLTYFQQQ 855
>UniRef50_UPI0000E80D01 Cluster: PREDICTED: similar to microtubule
associated protein 1A; n=2; Amniota|Rep: PREDICTED:
similar to microtubule associated protein 1A - Gallus
gallus
Length = 2250
Score = 31.9 bits (69), Expect = 9.4
Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
Frame = +3
Query: 276 TPAKVSGHKGPEELSXAI-KDADVVVIPXGVPREPGMTRDDLF-----NTNASIVRDIAL 437
TP K K P+ + +D P GV +P T D++ N S+V I
Sbjct: 2060 TPVKQPSDKSPKSATAKKERDGGEKPKPRGVLVQPPHTEDEVARSSHSNAGKSLVNGIKS 2119
Query: 438 SIAXNAPKAIVAIITNPVNFYS-ALLPLKCS 527
+ A N+PK+ + + T P + A +P CS
Sbjct: 2120 NPASNSPKSSLPVPTGPPVYVDLAYIPNHCS 2150
>UniRef50_UPI000023EEAF Cluster: hypothetical protein FG02077.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG02077.1 - Gibberella zeae PH-1
Length = 184
Score = 31.9 bits (69), Expect = 9.4
Identities = 15/40 (37%), Positives = 22/40 (55%)
Frame = +3
Query: 207 TRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXA 326
T A +AP+ P AA+ +TPA + KGPE+ + A
Sbjct: 126 TAAATTTVAPIIPTTAAEEPATSTPAAATPTKGPEQANGA 165
>UniRef50_Q91LF0 Cluster: ORF90; n=1; Shrimp white spot syndrome
virus|Rep: ORF90 - White spot syndrome virus (WSSV)
Length = 759
Score = 31.9 bits (69), Expect = 9.4
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Frame = +3
Query: 222 YDIAPVTPG--VAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPX-GVPREPGMTRD 392
+D+ P TPG V + K +G +G EE ++ + + P PR PG RD
Sbjct: 664 FDLPPATPGRNVEEIIKAQRQAVKETGVRGEEE-----EEEEAFIAPIIRQPRTPGNFRD 718
Query: 393 DLFNTNASI 419
+L + N SI
Sbjct: 719 ELLDVNESI 727
>UniRef50_Q8XN38 Cluster: Probable hexosyltransferase; n=1;
Clostridium perfringens|Rep: Probable hexosyltransferase
- Clostridium perfringens
Length = 409
Score = 31.9 bits (69), Expect = 9.4
Identities = 15/33 (45%), Positives = 19/33 (57%)
Frame = +3
Query: 258 DLSHVNTPAKVSGHKGPEELSXAIKDADVVVIP 356
D S ++T K G PEEL DADV++IP
Sbjct: 277 DSSEIDTRIKYLGKLNPEELKQQYIDADVLIIP 309
>UniRef50_Q1GZK2 Cluster: Putative partition-related protein; n=1;
Methylobacillus flagellatus KT|Rep: Putative
partition-related protein - Methylobacillus flagellatus
(strain KT / ATCC 51484 / DSM 6875)
Length = 210
Score = 31.9 bits (69), Expect = 9.4
Identities = 20/54 (37%), Positives = 32/54 (59%), Gaps = 1/54 (1%)
Frame = +3
Query: 240 TPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPR-EPGMTRDDL 398
T ++AD + V++PA + G K L A+KDAD++++P + G TRD L
Sbjct: 68 TNSLSADWTIVDSPAGLRGDK----LKQAVKDADLILVPMQPSAFDMGATRDFL 117
>UniRef50_Q47706 Cluster: Membrane-associated protein uidC
precursor; n=22; Enterobacteriaceae|Rep:
Membrane-associated protein uidC precursor - Escherichia
coli (strain K12)
Length = 421
Score = 31.9 bits (69), Expect = 9.4
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Frame = +1
Query: 76 PLLYKMVQRTFPPHHRGTLKWWSLVPPVVSASLWPFY*SRI-LW 204
PL+ QRT P G L +W+L P + LW + SR+ LW
Sbjct: 141 PLMAGSSQRTLPTVSEGALGYWALTPNI---DLWGMWRSRVFLW 181
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 531,479,061
Number of Sequences: 1657284
Number of extensions: 10945802
Number of successful extensions: 30129
Number of sequences better than 10.0: 142
Number of HSP's better than 10.0 without gapping: 28958
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 30083
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 33455602480
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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