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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= maV30038
         (529 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

CR536548-1|CAG38785.1|  338|Homo sapiens MDH2 protein.                163   5e-40
BC001917-1|AAH01917.1|  338|Homo sapiens malate dehydrogenase 2,...   162   8e-40
AF047470-1|AAC03787.1|  338|Homo sapiens malate dehydrogenase pr...   162   8e-40
DQ402957-1|ABD77290.1|  305|Homo sapiens mitochondrial malate de...   151   1e-36
AC005077-1|AAS07425.1|  316|Homo sapiens unknown protein.             149   5e-36
BC014340-1|AAH14340.1|  234|Homo sapiens LDHAL6A protein protein.      39   0.009
AY581313-1|AAS93432.1|  332|Homo sapiens lactate dehydrogenase p...    39   0.009
AK131523-1|BAD18662.1|  332|Homo sapiens protein ( Homo sapiens ...    39   0.009
BC008735-1|AAH08735.2|  627|Homo sapiens FBXL10 protein protein.       33   0.82 
AK027692-1|BAB55301.1|  653|Homo sapiens protein ( Homo sapiens ...    33   0.82 
AK027440-1|BAB55112.1|  704|Homo sapiens protein ( Homo sapiens ...    33   0.82 
AJ459424-1|CAD30700.1| 1336|Homo sapiens JEMMA protein protein.        33   0.82 
AB031230-1|BAA97672.1|  827|Homo sapiens protein containing CXXC...    33   0.82 
M55172-1|AAA62824.1| 2316|Homo sapiens large aggregating cartila...    31   3.3  
S74659-1|AAC60643.2|  102|Homo sapiens aggrecan keratan sulfate ...    29   7.6  

>CR536548-1|CAG38785.1|  338|Homo sapiens MDH2 protein.
          Length = 338

 Score =  163 bits (395), Expect = 5e-40
 Identities = 81/149 (54%), Positives = 106/149 (71%)
 Frame = +3

Query: 48  MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 227
           M S  ++P + A++   ++FST++Q N K         IGQPL+LLLK +PLV+RL LYD
Sbjct: 1   MLSALVRPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57

Query: 228 IAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNT 407
           IA  TPGVAADLSH+ T A V G+ GPE+L   +K  DVVVIP GVPR+PGMTRDDLFNT
Sbjct: 58  IAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116

Query: 408 NASIVRDIALSIAXNAPKAIVAIITNPVN 494
           NA+IV  +  + A + P+A++ +I NPVN
Sbjct: 117 NATIVATLTAACAQHCPEAMICVIANPVN 145


>BC001917-1|AAH01917.1|  338|Homo sapiens malate dehydrogenase 2,
           NAD (mitochondrial) protein.
          Length = 338

 Score =  162 bits (393), Expect = 8e-40
 Identities = 81/149 (54%), Positives = 105/149 (70%)
 Frame = +3

Query: 48  MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 227
           M S   +P + A++   ++FST++Q N K         IGQPL+LLLK +PLV+RL LYD
Sbjct: 1   MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57

Query: 228 IAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNT 407
           IA  TPGVAADLSH+ T A V G+ GPE+L   +K  DVVVIP GVPR+PGMTRDDLFNT
Sbjct: 58  IAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116

Query: 408 NASIVRDIALSIAXNAPKAIVAIITNPVN 494
           NA+IV  +  + A + P+A++ +I NPVN
Sbjct: 117 NATIVATLTAACAQHCPEAMICVIANPVN 145


>AF047470-1|AAC03787.1|  338|Homo sapiens malate dehydrogenase
           precursor protein.
          Length = 338

 Score =  162 bits (393), Expect = 8e-40
 Identities = 81/149 (54%), Positives = 105/149 (70%)
 Frame = +3

Query: 48  MFSRALKPAALAVQNGAKNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYD 227
           M S   +P + A++   ++FST++Q N K         IGQPL+LLLK +PLV+RL LYD
Sbjct: 1   MLSALARPVSAALR---RSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYD 57

Query: 228 IAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNT 407
           IA  TPGVAADLSH+ T A V G+ GPE+L   +K  DVVVIP GVPR+PGMTRDDLFNT
Sbjct: 58  IAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNT 116

Query: 408 NASIVRDIALSIAXNAPKAIVAIITNPVN 494
           NA+IV  +  + A + P+A++ +I NPVN
Sbjct: 117 NATIVATLTAACAQHCPEAMICVIANPVN 145


>DQ402957-1|ABD77290.1|  305|Homo sapiens mitochondrial malate
           dehydrogenase 2, NAD protein.
          Length = 305

 Score =  151 bits (367), Expect = 1e-36
 Identities = 74/125 (59%), Positives = 90/125 (72%)
 Frame = +3

Query: 120 QRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGH 299
           Q N K         IGQPL+LLLK +PLV+RL LYDIA  TPGVAADLSH+ T A V G+
Sbjct: 1   QNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH-TPGVAADLSHIETKAAVKGY 59

Query: 300 KGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAII 479
            GPE+L   +K  DVVVIP GVPR+PGMTRDDLFNTNA+IV  +  + A + P+A++ +I
Sbjct: 60  LGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVI 119

Query: 480 TNPVN 494
            NPVN
Sbjct: 120 ANPVN 124


>AC005077-1|AAS07425.1|  316|Homo sapiens unknown protein.
          Length = 316

 Score =  149 bits (362), Expect = 5e-36
 Identities = 71/111 (63%), Positives = 87/111 (78%)
 Frame = +3

Query: 162 IGQPLALLLKQNPLVTRLALYDIAPVTPGVAADLSHVNTPAKVSGHKGPEELSXAIKDAD 341
           IGQPL+LLLK +PLV+RL LYDIA  TPGVAADLSH+ T A V G+ GPE+L   +K  D
Sbjct: 14  IGQPLSLLLKNSPLVSRLTLYDIAH-TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCD 72

Query: 342 VVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNAPKAIVAIITNPVN 494
           VVVIP GVPR+PGMTRDDLFNTNA+IV  +  + A + P+A++ +I NPVN
Sbjct: 73  VVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVN 123


>BC014340-1|AAH14340.1|  234|Homo sapiens LDHAL6A protein protein.
          Length = 234

 Score = 39.1 bits (87), Expect = 0.009
 Identities = 32/133 (24%), Positives = 56/133 (42%), Gaps = 1/133 (0%)
 Frame = +3

Query: 99  KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVN 275
           KNF+     +           +G   A+ +    L   L L D+      G   DL H +
Sbjct: 10  KNFAEEEAIHHNKISIVGTGSVGVACAISILLKGLSDELVLVDVDEGKLKGETMDLQHGS 69

Query: 276 TPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNA 455
              K+      ++      ++++V+I  G  ++ G TR DL   N SI + +  +I   +
Sbjct: 70  PFMKMPNIVSSKDY-LVTANSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYS 128

Query: 456 PKAIVAIITNPVN 494
           P   + I+TNPV+
Sbjct: 129 PHCKLLIVTNPVD 141


>AY581313-1|AAS93432.1|  332|Homo sapiens lactate dehydrogenase
           protein.
          Length = 332

 Score = 39.1 bits (87), Expect = 0.009
 Identities = 32/133 (24%), Positives = 56/133 (42%), Gaps = 1/133 (0%)
 Frame = +3

Query: 99  KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVN 275
           KNF+     +           +G   A+ +    L   L L D+      G   DL H +
Sbjct: 10  KNFAEEEAIHHNKISIVGTGSVGVACAISILLKGLSDELVLVDVDEGKLKGETMDLQHGS 69

Query: 276 TPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNA 455
              K+      ++      ++++V+I  G  ++ G TR DL   N SI + +  +I   +
Sbjct: 70  PFMKMPNIVSSKDY-LVTANSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYS 128

Query: 456 PKAIVAIITNPVN 494
           P   + I+TNPV+
Sbjct: 129 PHCKLLIVTNPVD 141


>AK131523-1|BAD18662.1|  332|Homo sapiens protein ( Homo sapiens
           cDNA FLJ43406 fis, clone OCBBF2019823, highly  similar
           to Homo sapiens lactate dehydrogenase A -like (LDHL). ).
          Length = 332

 Score = 39.1 bits (87), Expect = 0.009
 Identities = 32/133 (24%), Positives = 56/133 (42%), Gaps = 1/133 (0%)
 Frame = +3

Query: 99  KNFSTTSQRNFKXXXXXXXXXIGQPLALLLKQNPLVTRLALYDIAP-VTPGVAADLSHVN 275
           KNF+     +           +G   A+ +    L   L L D+      G   DL H +
Sbjct: 10  KNFAEEEAIHHNKISIVGTGSVGVACAISILLKGLSDELVLVDVDEGKLKGETMDLQHGS 69

Query: 276 TPAKVSGHKGPEELSXAIKDADVVVIPXGVPREPGMTRDDLFNTNASIVRDIALSIAXNA 455
              K+      ++      ++++V+I  G  ++ G TR DL   N SI + +  +I   +
Sbjct: 70  PFMKMPNIVSSKDY-LVTANSNLVIITAGARQKKGETRLDLVQRNVSIFKLMIPNITQYS 128

Query: 456 PKAIVAIITNPVN 494
           P   + I+TNPV+
Sbjct: 129 PHCKLLIVTNPVD 141


>BC008735-1|AAH08735.2|  627|Homo sapiens FBXL10 protein protein.
          Length = 627

 Score = 32.7 bits (71), Expect = 0.82
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -2

Query: 144 RPPL*SSSVMWWKSSLHHFVQQ 79
           RPPL SS   WW+SSL +F QQ
Sbjct: 125 RPPLGSSLSPWWRSSLTYFQQQ 146


>AK027692-1|BAB55301.1|  653|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14786 fis, clone NT2RP4000737, moderately
           similar to Mus musculus F-box protein FBL10 mRNA. ).
          Length = 653

 Score = 32.7 bits (71), Expect = 0.82
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -2

Query: 144 RPPL*SSSVMWWKSSLHHFVQQ 79
           RPPL SS   WW+SSL +F QQ
Sbjct: 151 RPPLGSSLSPWWRSSLTYFQQQ 172


>AK027440-1|BAB55112.1|  704|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14534 fis, clone NT2RM2000599, weakly similar to
           Homo sapiens F-box protein Lilina (LILINA) mRNA. ).
          Length = 704

 Score = 32.7 bits (71), Expect = 0.82
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -2

Query: 144 RPPL*SSSVMWWKSSLHHFVQQ 79
           RPPL SS   WW+SSL +F QQ
Sbjct: 202 RPPLGSSLSPWWRSSLTYFQQQ 223


>AJ459424-1|CAD30700.1| 1336|Homo sapiens JEMMA protein protein.
          Length = 1336

 Score = 32.7 bits (71), Expect = 0.82
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -2

Query: 144 RPPL*SSSVMWWKSSLHHFVQQ 79
           RPPL SS   WW+SSL +F QQ
Sbjct: 834 RPPLGSSLSPWWRSSLTYFQQQ 855


>AB031230-1|BAA97672.1|  827|Homo sapiens protein containing CXXC
           domain 2 protein.
          Length = 827

 Score = 32.7 bits (71), Expect = 0.82
 Identities = 14/22 (63%), Positives = 16/22 (72%)
 Frame = -2

Query: 144 RPPL*SSSVMWWKSSLHHFVQQ 79
           RPPL SS   WW+SSL +F QQ
Sbjct: 358 RPPLGSSLSPWWRSSLTYFQQQ 379


>M55172-1|AAA62824.1| 2316|Homo sapiens large aggregating cartilage
           proteoglycan core protein protein.
          Length = 2316

 Score = 30.7 bits (66), Expect = 3.3
 Identities = 14/44 (31%), Positives = 20/44 (45%)
 Frame = +2

Query: 167 PAFGPSTEAESSGDQAGFIRHSACDPRRRSRPFPREHPSQGQRP 298
           P  G  TE  + G  A  +  ++ +P     PFP E PS  + P
Sbjct: 761 PPTGAETEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEP 804


>S74659-1|AAC60643.2|  102|Homo sapiens aggrecan keratan sulfate
           domain protein.
          Length = 102

 Score = 29.5 bits (63), Expect = 7.6
 Identities = 13/41 (31%), Positives = 20/41 (48%)
 Frame = +2

Query: 176 GPSTEAESSGDQAGFIRHSACDPRRRSRPFPREHPSQGQRP 298
           G +TE  + G  A  +  ++ +P     PFP E PS  + P
Sbjct: 1   GAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEP 41


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 79,414,903
Number of Sequences: 237096
Number of extensions: 1778302
Number of successful extensions: 3987
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 3786
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3982
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 5103531180
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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