Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= maV30037
(585 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for ... 138 1e-32
X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for ... 138 1e-32
M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase E1... 138 1e-32
M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate ... 138 1e-32
L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase E1... 138 1e-32
J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase al... 138 1e-32
J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein. 138 1e-32
D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase al... 138 1e-32
BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase ... 138 1e-32
AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase ... 138 1e-32
AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase ... 138 1e-32
AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase ... 138 1e-32
AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase ... 138 1e-32
EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1 pro... 134 2e-31
AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase ... 134 2e-31
AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase ... 129 6e-30
M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase co... 126 6e-29
BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase ... 126 6e-29
BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase ... 126 6e-29
BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase ... 126 6e-29
BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase ... 126 6e-29
BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein. 126 6e-29
BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase ... 126 6e-29
BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase ... 125 1e-28
L48690-1|AAB59581.1| 390|Homo sapiens pyruvate dehydrogenase E1... 93 9e-19
AL732326-3|CAI41287.1| 121|Homo sapiens pyruvate dehydrogenase ... 77 6e-14
>X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for
liver pyruvate dehydrogenase (EC 1.2.4.1) E1' subunit.
).
Length = 390
Score = 138 bits (335), Expect = 1e-32
Identities = 66/148 (44%), Positives = 96/148 (64%)
Frame = +3
Query: 141 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 320
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 321 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 500
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 501 YRCHGWTYLMGVSVLGVLSELTGRRTGC 584
YR HG+T+ G+SV +L+ELTGR+ GC
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGC 145
>X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for
brain pyruvate dehydrogenase (EC 1.2.4.1). ).
Length = 390
Score = 138 bits (335), Expect = 1e-32
Identities = 66/148 (44%), Positives = 96/148 (64%)
Frame = +3
Query: 141 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 320
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 321 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 500
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 501 YRCHGWTYLMGVSVLGVLSELTGRRTGC 584
YR HG+T+ G+SV +L+ELTGR+ GC
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGC 145
>M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 138 bits (335), Expect = 1e-32
Identities = 66/148 (44%), Positives = 96/148 (64%)
Frame = +3
Query: 141 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 320
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 321 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 500
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 501 YRCHGWTYLMGVSVLGVLSELTGRRTGC 584
YR HG+T+ G+SV +L+ELTGR+ GC
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGC 145
>M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate
dehydrogenase alpha subunit mRNA, complete cds. ).
Length = 390
Score = 138 bits (335), Expect = 1e-32
Identities = 66/148 (44%), Positives = 96/148 (64%)
Frame = +3
Query: 141 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 320
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 321 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 500
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 501 YRCHGWTYLMGVSVLGVLSELTGRRTGC 584
YR HG+T+ G+SV +L+ELTGR+ GC
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGC 145
>L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 138 bits (335), Expect = 1e-32
Identities = 66/148 (44%), Positives = 96/148 (64%)
Frame = +3
Query: 141 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 320
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 321 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 500
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 501 YRCHGWTYLMGVSVLGVLSELTGRRTGC 584
YR HG+T+ G+SV +L+ELTGR+ GC
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGC 145
>J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 138 bits (335), Expect = 1e-32
Identities = 66/148 (44%), Positives = 96/148 (64%)
Frame = +3
Query: 141 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 320
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 321 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 500
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 501 YRCHGWTYLMGVSVLGVLSELTGRRTGC 584
YR HG+T+ G+SV +L+ELTGR+ GC
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGC 145
>J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein.
Length = 414
Score = 138 bits (335), Expect = 1e-32
Identities = 66/148 (44%), Positives = 96/148 (64%)
Frame = +3
Query: 141 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 320
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 25 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 81
Query: 321 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 500
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 82 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 141
Query: 501 YRCHGWTYLMGVSVLGVLSELTGRRTGC 584
YR HG+T+ G+SV +L+ELTGR+ GC
Sbjct: 142 YRAHGFTFTRGLSVREILAELTGRKGGC 169
>D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 138 bits (335), Expect = 1e-32
Identities = 66/148 (44%), Positives = 96/148 (64%)
Frame = +3
Query: 141 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 320
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 321 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 500
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 501 YRCHGWTYLMGVSVLGVLSELTGRRTGC 584
YR HG+T+ G+SV +L+ELTGR+ GC
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGC 145
>BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 138 bits (335), Expect = 1e-32
Identities = 66/148 (44%), Positives = 96/148 (64%)
Frame = +3
Query: 141 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 320
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 321 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 500
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 501 YRCHGWTYLMGVSVLGVLSELTGRRTGC 584
YR HG+T+ G+SV +L+ELTGR+ GC
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGC 145
>AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 138 bits (335), Expect = 1e-32
Identities = 66/148 (44%), Positives = 96/148 (64%)
Frame = +3
Query: 141 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 320
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 321 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 500
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 501 YRCHGWTYLMGVSVLGVLSELTGRRTGC 584
YR HG+T+ G+SV +L+ELTGR+ GC
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGC 145
>AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 180
Score = 138 bits (335), Expect = 1e-32
Identities = 66/148 (44%), Positives = 96/148 (64%)
Frame = +3
Query: 141 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 320
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 321 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 500
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 501 YRCHGWTYLMGVSVLGVLSELTGRRTGC 584
YR HG+T+ G+SV +L+ELTGR+ GC
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGC 145
>AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 138 bits (335), Expect = 1e-32
Identities = 66/148 (44%), Positives = 96/148 (64%)
Frame = +3
Query: 141 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 320
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 321 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 500
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 501 YRCHGWTYLMGVSVLGVLSELTGRRTGC 584
YR HG+T+ G+SV +L+ELTGR+ GC
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGC 145
>AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 138 bits (335), Expect = 1e-32
Identities = 66/148 (44%), Positives = 96/148 (64%)
Frame = +3
Query: 141 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 320
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 321 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 500
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 501 YRCHGWTYLMGVSVLGVLSELTGRRTGC 584
YR HG+T+ G+SV +L+ELTGR+ GC
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGC 145
>EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1
protein.
Length = 428
Score = 134 bits (324), Expect = 2e-31
Identities = 60/113 (53%), Positives = 79/113 (69%)
Frame = +3
Query: 246 EATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCH 425
+ATFEIK LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCH
Sbjct: 71 DATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCH 130
Query: 426 LYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
L GQEA VG+ A + D +ITAYR HG+T+ G+SV +L+ELTGR+ GC
Sbjct: 131 LCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGC 183
>AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 205
Score = 134 bits (324), Expect = 2e-31
Identities = 60/113 (53%), Positives = 79/113 (69%)
Frame = +3
Query: 246 EATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCH 425
+ATFEIK LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCH
Sbjct: 71 DATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCH 130
Query: 426 LYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
L GQEA VG+ A + D +ITAYR HG+T+ G+SV +L+ELTGR+ GC
Sbjct: 131 LCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGC 183
>AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 204
Score = 129 bits (312), Expect = 6e-30
Identities = 66/155 (42%), Positives = 96/155 (61%), Gaps = 7/155 (4%)
Frame = +3
Query: 141 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 320
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 321 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSG-------QEAVAVGMRAAMRD 479
ED LK Y + +RR+E + LYK+KIIRGFCHL G QEA VG+ A +
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQFLLPLTQEACCVGLEAGINP 117
Query: 480 ADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
D +ITAYR HG+T+ G+SV +L+ELTGR+ GC
Sbjct: 118 TDHLITAYRAHGFTFTRGLSVREILAELTGRKGGC 152
>M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase
complex protein.
Length = 388
Score = 126 bits (304), Expect = 6e-29
Identities = 58/120 (48%), Positives = 78/120 (65%)
Frame = +3
Query: 225 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 404
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 405 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
>BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 126 bits (304), Expect = 6e-29
Identities = 58/120 (48%), Positives = 78/120 (65%)
Frame = +3
Query: 225 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 404
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 405 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
>BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 126 bits (304), Expect = 6e-29
Identities = 58/120 (48%), Positives = 78/120 (65%)
Frame = +3
Query: 225 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 404
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 405 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
>BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 126 bits (304), Expect = 6e-29
Identities = 58/120 (48%), Positives = 78/120 (65%)
Frame = +3
Query: 225 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 404
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 405 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
>BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 126 bits (304), Expect = 6e-29
Identities = 58/120 (48%), Positives = 78/120 (65%)
Frame = +3
Query: 225 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 404
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 405 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
>BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein.
Length = 407
Score = 126 bits (304), Expect = 6e-29
Identities = 58/120 (48%), Positives = 78/120 (65%)
Frame = +3
Query: 225 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 404
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 43 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 102
Query: 405 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 103 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 162
>BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 126 bits (304), Expect = 6e-29
Identities = 58/120 (48%), Positives = 78/120 (65%)
Frame = +3
Query: 225 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 404
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 405 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
>BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 125 bits (301), Expect = 1e-28
Identities = 58/120 (48%), Positives = 77/120 (64%)
Frame = +3
Query: 225 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 404
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 405 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 584
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGPSVRSILAELTGRRGGC 143
>L48690-1|AAB59581.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit precursor protein.
Length = 390
Score = 92.7 bits (220), Expect = 9e-19
Identities = 46/110 (41%), Positives = 67/110 (60%)
Frame = +3
Query: 141 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 320
M K++ + + L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSPVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 321 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAA 470
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLERA 107
>AL732326-3|CAI41287.1| 121|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 121
Score = 76.6 bits (180), Expect = 6e-14
Identities = 33/61 (54%), Positives = 43/61 (70%)
Frame = +3
Query: 246 EATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCH 425
+ATFEIK LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCH
Sbjct: 61 DATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCH 120
Query: 426 L 428
L
Sbjct: 121 L 121
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 80,580,079
Number of Sequences: 237096
Number of extensions: 1529203
Number of successful extensions: 3390
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 3256
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3389
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 6098631048
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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