BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= maV30033 (638 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q1G151 Cluster: Putative alcohol dehydrogenase; n=1; Bo... 173 4e-42 UniRef50_Q6RUR3 Cluster: Putative alcohol dehydrogenase; n=2; Ne... 156 4e-37 UniRef50_Q6NYE8 Cluster: Zgc:56585 protein; n=5; Clupeocephala|R... 154 2e-36 UniRef50_UPI0000DB7440 Cluster: PREDICTED: similar to 15-hydroxy... 150 2e-35 UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative a... 143 3e-33 UniRef50_UPI00015B5316 Cluster: PREDICTED: similar to putative a... 142 8e-33 UniRef50_UPI00015B573D Cluster: PREDICTED: similar to putative a... 141 1e-32 UniRef50_UPI0000513348 Cluster: PREDICTED: similar to 15-hydroxy... 140 3e-32 UniRef50_UPI00015B4C63 Cluster: PREDICTED: similar to putative a... 138 8e-32 UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative a... 131 2e-29 UniRef50_UPI00015B42E2 Cluster: PREDICTED: similar to putative a... 131 2e-29 UniRef50_UPI00015B5A58 Cluster: PREDICTED: similar to putative a... 128 8e-29 UniRef50_UPI000051334A Cluster: PREDICTED: similar to 15-hydroxy... 128 1e-28 UniRef50_UPI00015B5FC8 Cluster: PREDICTED: similar to putative a... 126 6e-28 UniRef50_UPI0000D57364 Cluster: PREDICTED: similar to 15-hydroxy... 126 6e-28 UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|R... 124 2e-27 UniRef50_P15428 Cluster: 15-hydroxyprostaglandin dehydrogenase [... 121 1e-26 UniRef50_UPI0000E47587 Cluster: PREDICTED: similar to 15-hydroxy... 121 2e-26 UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative a... 120 3e-26 UniRef50_Q1HPX6 Cluster: Alcohol dehydrogenase; n=1; Bombyx mori... 120 4e-26 UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to hydroxypro... 118 1e-25 UniRef50_Q7PY55 Cluster: ENSANGP00000013280; n=4; Endopterygota|... 117 2e-25 UniRef50_UPI0000D57365 Cluster: PREDICTED: similar to CG4899-PA,... 114 2e-24 UniRef50_UPI00015B572C Cluster: PREDICTED: similar to putative a... 107 3e-22 UniRef50_Q9I7R3 Cluster: CG18814-PA; n=3; Sophophora|Rep: CG1881... 103 3e-21 UniRef50_UPI0000D5767E Cluster: PREDICTED: similar to 15-hydroxy... 101 2e-20 UniRef50_Q9NAR7 Cluster: Alcohol dehydrogenase; n=23; Schizophor... 97 4e-19 UniRef50_Q5P8S6 Cluster: Putative dehydrogenase; n=4; Proteobact... 96 5e-19 UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR... 94 3e-18 UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella ve... 93 4e-18 UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain dehydrogena... 93 5e-18 UniRef50_A6YPS8 Cluster: Oxidoreductase; n=1; Triatoma infestans... 93 5e-18 UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR... 93 7e-18 UniRef50_Q9ABI1 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 92 9e-18 UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1; ... 92 1e-17 UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase fam... 91 2e-17 UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: O... 90 4e-17 UniRef50_Q5TWK5 Cluster: ENSANGP00000025423; n=1; Anopheles gamb... 90 5e-17 UniRef50_Q6C6W8 Cluster: Similar to tr|Q9WYD3 Thermotoga maritim... 89 1e-16 UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR... 87 3e-16 UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillu... 87 3e-16 UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 87 4e-16 UniRef50_Q2W431 Cluster: Dehydrogenase with different specificit... 86 8e-16 UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR... 86 8e-16 UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reducta... 85 1e-15 UniRef50_Q89M15 Cluster: Dehydrogenase; n=3; Proteobacteria|Rep:... 85 1e-15 UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 85 1e-15 UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR... 85 1e-15 UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR... 85 2e-15 UniRef50_P91615 Cluster: Alcohol dehydrogenase-related 31 kDa pr... 84 3e-15 UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase b... 83 4e-15 UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyc... 83 5e-15 UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR... 83 5e-15 UniRef50_P00334 Cluster: Alcohol dehydrogenase; n=485; Drosophil... 83 5e-15 UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 83 7e-15 UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 83 7e-15 UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3; Bacill... 82 1e-14 UniRef50_Q6XPZ7 Cluster: Short-chain dehydrogenase/reductase; n=... 82 1e-14 UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacte... 81 2e-14 UniRef50_Q89KQ8 Cluster: Blr4846 protein; n=2; Proteobacteria|Re... 81 2e-14 UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogena... 81 3e-14 UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR... 81 3e-14 UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR... 80 4e-14 UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;... 80 4e-14 UniRef50_Q8YQR6 Cluster: All3753 protein; n=6; Bacteria|Rep: All... 80 5e-14 UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain dehydrogena... 80 5e-14 UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR... 80 5e-14 UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1; Psychro... 80 5e-14 UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 79 7e-14 UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;... 79 7e-14 UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 79 9e-14 UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR... 79 9e-14 UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR... 79 9e-14 UniRef50_Q6UWP2 Cluster: Dehydrogenase/reductase SDR family memb... 79 9e-14 UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2; Bacteri... 79 1e-13 UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductas... 79 1e-13 UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 79 1e-13 UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR... 79 1e-13 UniRef50_A1IFS9 Cluster: Short chain dehydrogenase family protei... 79 1e-13 UniRef50_Q28GY1 Cluster: Novel protein containing short chain de... 78 2e-13 UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Li... 78 2e-13 UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 78 2e-13 UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 78 2e-13 UniRef50_Q399N8 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2; Actinom... 78 2e-13 UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Sho... 78 2e-13 UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR... 78 2e-13 UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=... 78 2e-13 UniRef50_Q15Q07 Cluster: Short-chain dehydrogenase/reductase SDR... 77 3e-13 UniRef50_Q9FX95 Cluster: ARP protein; n=8; Magnoliophyta|Rep: AR... 77 3e-13 UniRef50_A5BP77 Cluster: Putative uncharacterized protein; n=1; ... 77 3e-13 UniRef50_P54398 Cluster: Fat body protein 2; n=6; Schizophora|Re... 77 3e-13 UniRef50_P19871 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=... 77 3e-13 UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular ... 77 4e-13 UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep... 77 4e-13 UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammapr... 77 4e-13 UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR... 77 4e-13 UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4; Brucel... 77 5e-13 UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SD... 77 5e-13 UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR... 77 5e-13 UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogena... 77 5e-13 UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x;... 77 5e-13 UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain dehydrogena... 76 6e-13 UniRef50_Q97EW4 Cluster: Predicted short-chain dehydrogenase; n=... 76 6e-13 UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain dehydrogena... 76 6e-13 UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase... 76 6e-13 UniRef50_Q2UEK6 Cluster: Dehydrogenases with different specifici... 76 6e-13 UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase, puta... 76 6e-13 UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 76 6e-13 UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 76 6e-13 UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20; ... 76 8e-13 UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reducta... 76 8e-13 UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 76 8e-13 UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13 UniRef50_A1UMZ0 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13 UniRef50_A0X2J5 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13 UniRef50_A0LZZ5 Cluster: Short-chain dehydrogenase/reductase fam... 76 8e-13 UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR... 76 8e-13 UniRef50_Q22CU9 Cluster: Oxidoreductase, short chain dehydrogena... 76 8e-13 UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 76 8e-13 UniRef50_UPI0000E465C5 Cluster: PREDICTED: similar to MGC80593 p... 75 1e-12 UniRef50_A4XF64 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_Q82FK0 Cluster: Putative dehydrogenase; n=2; Streptomyc... 75 1e-12 UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 75 1e-12 UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 75 1e-12 UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_A0HI81 Cluster: Short-chain dehydrogenase/reductase SDR... 75 1e-12 UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;... 75 1e-12 UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019;... 75 1e-12 UniRef50_Q71R50 Cluster: Dehydrogenase/reductase SDR family memb... 75 1e-12 UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 75 2e-12 UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12 UniRef50_Q0VL04 Cluster: Oxidoreductase, putative; n=1; Alcanivo... 75 2e-12 UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chai... 74 3e-12 UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR... 74 3e-12 UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR... 74 3e-12 UniRef50_A6UZF9 Cluster: Oxidoreductase, short chain dehydrogena... 74 3e-12 UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1; ... 74 3e-12 UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8;... 74 3e-12 UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=... 74 3e-12 UniRef50_Q54D03 Cluster: Putative uncharacterized protein; n=1; ... 74 3e-12 UniRef50_UPI00015B572E Cluster: PREDICTED: similar to putative a... 74 3e-12 UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 74 3e-12 UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacill... 74 3e-12 UniRef50_Q12G63 Cluster: Short-chain dehydrogenase/reductase SDR... 74 3e-12 UniRef50_A6CTS3 Cluster: Putative uncharacterized protein; n=1; ... 74 3e-12 UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like ... 74 3e-12 UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR... 74 3e-12 UniRef50_Q13H99 Cluster: Putative short-chain dehydrogenase/redu... 73 4e-12 UniRef50_A7IMM1 Cluster: Short-chain dehydrogenase/reductase SDR... 73 4e-12 UniRef50_A6BFV0 Cluster: Putative uncharacterized protein; n=1; ... 73 4e-12 UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protei... 73 4e-12 UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Re... 73 4e-12 UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34; Proteo... 73 4e-12 UniRef50_P50197 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 73 4e-12 UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oc... 73 6e-12 UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 73 6e-12 UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 73 6e-12 UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-car... 73 6e-12 UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR... 73 6e-12 UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4; Legion... 73 6e-12 UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR... 73 6e-12 UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -... 73 8e-12 UniRef50_Q8FA17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 73 8e-12 UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR... 73 8e-12 UniRef50_Q2JG54 Cluster: Short-chain dehydrogenase/reductase SDR... 73 8e-12 UniRef50_Q1IPJ3 Cluster: Short-chain dehydrogenase/reductase SDR... 73 8e-12 UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase prec... 73 8e-12 UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR... 73 8e-12 UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain dehydrogena... 73 8e-12 UniRef50_A2U319 Cluster: Short-chain dehydrogenase/reductase SDR... 73 8e-12 UniRef50_A1BFL6 Cluster: Short-chain dehydrogenase/reductase SDR... 73 8e-12 UniRef50_Q2U0U8 Cluster: Dehydrogenases with different specifici... 73 8e-12 UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627;... 73 8e-12 UniRef50_P66778 Cluster: Probable oxidoreductase ephD; n=16; Myc... 73 8e-12 UniRef50_Q7M9W0 Cluster: 3-OXOACYL-REDUCTASE; n=24; Epsilonprote... 72 1e-11 UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_Q0GL61 Cluster: Short-chain dehydrogenase; n=3; Lactoba... 72 1e-11 UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bac... 72 1e-11 UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A0VFC2 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh... 72 1e-11 UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 72 1e-11 UniRef50_Q48I17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 72 1e-11 UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 72 1e-11 UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogena... 72 1e-11 UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A0Z215 Cluster: Short chain dehydrogenase; n=2; Gammapr... 72 1e-11 UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11 UniRef50_A7EQI6 Cluster: Putative uncharacterized protein; n=1; ... 72 1e-11 UniRef50_Q5UYC2 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 72 1e-11 UniRef50_UPI00015B4F48 Cluster: PREDICTED: similar to ENSANGP000... 71 2e-11 UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 71 2e-11 UniRef50_Q0S5L2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 71 2e-11 UniRef50_A7AZH2 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11 UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR... 71 2e-11 UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 71 2e-11 UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60; Bacteria|... 71 2e-11 UniRef50_Q3IVD0 Cluster: Short-chain alcohol dehydrogenases; n=2... 71 2e-11 UniRef50_Q03X86 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11 UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5; Proteob... 71 2e-11 UniRef50_Q0D3V4 Cluster: Os07g0664000 protein; n=34; cellular or... 71 2e-11 UniRef50_Q7SI45 Cluster: Putative uncharacterized protein NCU006... 71 2e-11 UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family memb... 71 2e-11 UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular o... 71 3e-11 UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1... 71 3e-11 UniRef50_Q3VZL7 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11 UniRef50_Q1V2H3 Cluster: Short chain dehydrogenase; n=2; Candida... 71 3e-11 UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11 UniRef50_Q11ZZ1 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11 UniRef50_O33454 Cluster: P-cumic alcohol dehydrogenase; n=3; Pro... 71 3e-11 UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain dehydrogena... 71 3e-11 UniRef50_A3JFT9 Cluster: Short chain dehydrogenase; n=1; Marinob... 71 3e-11 UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11 UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11 UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR... 71 3e-11 UniRef50_P54554 Cluster: Uncharacterized oxidoreductase yqjQ; n=... 71 3e-11 UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3; Clo... 71 3e-11 UniRef50_Q9C826 Cluster: Xanthoxin dehydrogenase; n=41; Magnolio... 71 3e-11 UniRef50_Q8EQ60 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 70 4e-11 UniRef50_Q88SD1 Cluster: Short-chain dehydrogenase/oxidoreductas... 70 4e-11 UniRef50_Q11E37 Cluster: Short-chain dehydrogenase/reductase SDR... 70 4e-11 UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR... 70 4e-11 UniRef50_A4B8L3 Cluster: Short chain dehydrogenase; n=1; Alterom... 70 4e-11 UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 70 4e-11 UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogena... 70 4e-11 UniRef50_Q965D6 Cluster: 3-oxoacyl-acyl-carrier protein reductas... 70 4e-11 UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59; cell... 70 4e-11 UniRef50_Q81WX9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 70 5e-11 UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia succinici... 70 5e-11 UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxid... 70 5e-11 UniRef50_Q39TR6 Cluster: Short-chain dehydrogenase/reductase SDR... 70 5e-11 UniRef50_A6EZZ8 Cluster: Short chain dehydrogenase; n=1; Marinob... 70 5e-11 UniRef50_A5WHV5 Cluster: Short-chain dehydrogenase/reductase SDR... 70 5e-11 UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR... 70 5e-11 UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR... 70 5e-11 UniRef50_O15744 Cluster: PksB; n=2; Dictyostelium discoideum|Rep... 70 5e-11 UniRef50_Q92EK7 Cluster: Uncharacterized oxidoreductase Lin0452;... 70 5e-11 UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2; Streptomyc... 69 7e-11 UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|R... 69 7e-11 UniRef50_Q5LMX2 Cluster: 20-beta-hydroxysteroid dehydrogenase, p... 69 7e-11 UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase pre... 69 7e-11 UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR... 69 7e-11 UniRef50_A6EGH2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 69 7e-11 UniRef50_A4TBK3 Cluster: Short-chain dehydrogenase/reductase SDR... 69 7e-11 UniRef50_A3XPR1 Cluster: Cyclohexanol dehydrogenase; n=1; Leeuwe... 69 7e-11 UniRef50_A3IK59 Cluster: Oxidoreductase, short chain dehydrogena... 69 7e-11 UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte... 69 7e-11 UniRef50_A0M3M9 Cluster: Short-chain dehydrogenase/reductase fam... 69 7e-11 UniRef50_Q0D3U7 Cluster: Os07g0665000 protein; n=18; Poales|Rep:... 69 7e-11 UniRef50_Q9VU92 Cluster: CG8757-PA; n=3; Drosophila melanogaster... 69 7e-11 UniRef50_Q22RI1 Cluster: Oxidoreductase, short chain dehydrogena... 69 7e-11 UniRef50_A7S4C5 Cluster: Predicted protein; n=1; Nematostella ve... 69 7e-11 UniRef50_Q2UV13 Cluster: Reductases with broad range of substrat... 69 7e-11 UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellula... 69 7e-11 UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 69 7e-11 UniRef50_Q89UC3 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 69 1e-10 UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogena... 69 1e-10 UniRef50_Q1VWP8 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=... 69 1e-10 UniRef50_Q1DDT9 Cluster: Oxidoreductase, short chain dehydrogena... 69 1e-10 UniRef50_Q02AD5 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_A6W2S3 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_A1UAJ6 Cluster: Acetoin reductases; n=18; Bacteria|Rep:... 69 1e-10 UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=... 69 1e-10 UniRef50_P19992 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh... 69 1e-10 UniRef50_P39071 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate dehyd... 69 1e-10 UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 69 1e-10 UniRef50_Q390G9 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_O86553 Cluster: Putative dehydrogenase; n=1; Streptomyc... 69 1e-10 UniRef50_Q1YZB6 Cluster: Short chain dehydrogenase; n=6; Gammapr... 69 1e-10 UniRef50_Q13GX3 Cluster: Putative short-chain dehydrogenase/redu... 69 1e-10 UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_A0PSR4 Cluster: Short-chain dehydrogenase; n=1; Mycobac... 69 1e-10 UniRef50_A2QS57 Cluster: Contig An08c0220, complete genome; n=2;... 69 1e-10 UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR... 69 1e-10 UniRef50_Q9ABX6 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 68 2e-10 UniRef50_Q8EPA2 Cluster: Hypothetical conserved protein; n=1; Oc... 68 2e-10 UniRef50_Q87GW0 Cluster: Acetoacetyl-CoA reductase; n=7; Vibrio|... 68 2e-10 UniRef50_Q62E12 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 68 2e-10 UniRef50_Q3EU48 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 68 2e-10 UniRef50_Q081K4 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A6W2Z2 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A4T9G9 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A0KYX3 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A0G4K1 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_Q890G1 Cluster: Short-chain dehydrogenase/oxidoreductas... 68 2e-10 UniRef50_Q7UJY8 Cluster: Probable short-chain dehydrogenase; n=1... 68 2e-10 UniRef50_Q7NCW8 Cluster: Gll2858 protein; n=6; Bacteria|Rep: Gll... 68 2e-10 UniRef50_Q1IU03 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_Q0B2G1 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A6T789 Cluster: Putative short-chain dehydrogenase/redu... 68 2e-10 UniRef50_A5V545 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10 UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 68 2e-10 UniRef50_A1ZK52 Cluster: Dehydrogenase/reductase SDR family memb... 68 2e-10 UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specifici... 67 3e-10 UniRef50_Q8CNF1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 67 3e-10 UniRef50_Q2SKD5 Cluster: Short-chain dehydrogenase of various su... 67 3e-10 UniRef50_Q2S7V4 Cluster: Short-chain alcohol dehydrogenase-like ... 67 3e-10 UniRef50_Q2IEG2 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_Q54472 Cluster: Oxido-reductase; n=3; Bacteria|Rep: Oxi... 67 3e-10 UniRef50_Q26DV9 Cluster: Short-chain dehydrogenases/reductases f... 67 3e-10 UniRef50_Q0M0K7 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_Q4WR19 Cluster: Short chain dehydrogenase, putative; n=... 67 3e-10 UniRef50_Q4J9S4 Cluster: Glucose 1-dehydrogenase; n=6; Thermopro... 67 3e-10 UniRef50_Q2FSZ0 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_A7DQI5 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10 UniRef50_Q62CL0 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 67 4e-10 UniRef50_Q3IKU0 Cluster: Putative 3-oxoacyl-[acyl-carrier protei... 67 4e-10 UniRef50_Q2GA84 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10 UniRef50_Q1YPA9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 67 4e-10 UniRef50_Q1ILJ4 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10 UniRef50_Q12QC5 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10 UniRef50_Q07KD0 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10 UniRef50_A5GRS5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 67 4e-10 UniRef50_A4ABL9 Cluster: Short-chain dehydrogenase/reductase SDR... 67 4e-10 UniRef50_Q8TMH3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 67 4e-10 UniRef50_Q56840 Cluster: 2-(R)-hydroxypropyl-CoM dehydrogenase; ... 67 4e-10 UniRef50_UPI0000DB6BA4 Cluster: PREDICTED: similar to 3-hydroxya... 66 5e-10 UniRef50_UPI00004996DD Cluster: 3-oxoacyl-(acyl-carrier protein)... 66 5e-10 UniRef50_Q930L5 Cluster: Putative; n=3; Proteobacteria|Rep: Puta... 66 5e-10 UniRef50_Q0SC53 Cluster: Dehydrogenase; n=3; Corynebacterineae|R... 66 5e-10 UniRef50_Q1IP02 Cluster: Short-chain dehydrogenase/reductase SDR... 66 5e-10 UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR... 66 5e-10 UniRef50_Q0RTV0 Cluster: Short-chain dehydrogenase, SDR family; ... 66 5e-10 UniRef50_Q0FWE6 Cluster: Putative oxidoreductase; n=1; Roseovari... 66 5e-10 UniRef50_A5TX02 Cluster: Short-chain alcohol dehydrogenase; n=3;... 66 5e-10 UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR... 66 5e-10 UniRef50_A1ZGN7 Cluster: Short-chain dehydrogenase/reductase SDR... 66 5e-10 UniRef50_A1K1F4 Cluster: Short-chain dehydrogenase family protei... 66 5e-10 UniRef50_A0Z7K1 Cluster: Short-chain dehydrogenase/reductase SDR... 66 5e-10 UniRef50_Q8TTL5 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 66 5e-10 UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methano... 66 5e-10 UniRef50_Q8DIS9 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 66 7e-10 UniRef50_Q3W0V5 Cluster: Short-chain dehydrogenase/reductase SDR... 66 7e-10 UniRef50_Q3S8D5 Cluster: Putative short-chain dehydrogenase/redu... 66 7e-10 UniRef50_Q1YS63 Cluster: Putative dehydrogenase; n=1; gamma prot... 66 7e-10 UniRef50_Q1YQ07 Cluster: Putative uncharacterized protein; n=1; ... 66 7e-10 UniRef50_Q11BT8 Cluster: Short-chain dehydrogenase/reductase SDR... 66 7e-10 UniRef50_A4BGV8 Cluster: Short chain dehydrogenase; n=1; Reineke... 66 7e-10 UniRef50_A4AQP7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 66 7e-10 UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular organisms... 66 7e-10 UniRef50_A2BJK2 Cluster: Short chain dehydrogenase; n=1; Hyperth... 66 7e-10 UniRef50_P40747 Cluster: Uncharacterized oxidoreductase yuxG; n=... 66 7e-10 UniRef50_UPI0000518CA5 Cluster: PREDICTED: similar to antdh CG13... 66 9e-10 UniRef50_UPI000050F9D4 Cluster: COG1028: Dehydrogenases with dif... 66 9e-10 UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 66 9e-10 UniRef50_Q8UAB0 Cluster: Dehydrogenase; n=1; Agrobacterium tumef... 66 9e-10 UniRef50_Q62E13 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 66 9e-10 UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_Q2S467 Cluster: NAD-binding domain 4, putative; n=1; Sa... 66 9e-10 UniRef50_Q9S3U5 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 66 9e-10 UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2; Corynebac... 66 9e-10 UniRef50_Q0B254 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_A1UEP6 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_A0UZI2 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_A0PSE4 Cluster: Short-chain type dehydrogenase; n=12; C... 66 9e-10 UniRef50_A0JVB1 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_A0FY63 Cluster: Short-chain dehydrogenase/reductase SDR... 66 9e-10 UniRef50_A6XGT9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 66 9e-10 UniRef50_Q9N5G3 Cluster: Dehydrogenases, short chain protein 14;... 66 9e-10 UniRef50_Q7Q3Q2 Cluster: ENSANGP00000007118; n=1; Anopheles gamb... 66 9e-10 UniRef50_Q16Q07 Cluster: Alcohol dehydrogenase, putative; n=1; A... 66 9e-10 UniRef50_Q8YVT0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 65 1e-09 UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 65 1e-09 UniRef50_Q55922 Cluster: Slr0315 protein; n=2; Bacteria|Rep: Slr... 65 1e-09 UniRef50_Q39TI0 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09 UniRef50_Q0VQZ0 Cluster: Oxidoreductase; n=4; Gammaproteobacteri... 65 1e-09 UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09 UniRef50_A6VY27 Cluster: Short-chain dehydrogenase/reductase SDR... 65 1e-09 UniRef50_A3TVX6 Cluster: Probable dehydrogenase; n=1; Oceanicola... 65 1e-09 UniRef50_A3I6G4 Cluster: Putative 7-alpha-hydroxysteroid dehydro... 65 1e-09 UniRef50_A1ZL47 Cluster: Oxidoreductase, short chain dehydrogena... 65 1e-09 UniRef50_Q6NNV7 Cluster: RH03309p; n=4; melanogaster subgroup|Re... 65 1e-09 UniRef50_Q988B7 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 65 2e-09 UniRef50_Q73Q46 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 65 2e-09 UniRef50_Q737G7 Cluster: Short chain dehydrogenase family protei... 65 2e-09 UniRef50_Q6MBQ9 Cluster: Putative uncharacterized protein; n=1; ... 65 2e-09 UniRef50_Q62GZ1 Cluster: Oxidoreductase, short chain dehydrogena... 65 2e-09 UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09 UniRef50_Q2IVN1 Cluster: Short-chain dehydrogenase/reductase; n=... 65 2e-09 UniRef50_Q2AGJ3 Cluster: NAD-dependent epimerase/dehydratase:Sho... 65 2e-09 UniRef50_Q1WVR8 Cluster: Short chain dehydrogenase; n=1; Lactoba... 65 2e-09 UniRef50_A7IJL6 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09 UniRef50_A6WBU5 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09 UniRef50_A5MZ18 Cluster: FabG2; n=2; Clostridia|Rep: FabG2 - Clo... 65 2e-09 UniRef50_A1U9L1 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09 UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1;... 65 2e-09 UniRef50_Q988J7 Cluster: Oxidoreductase, short chain dehydrogena... 64 2e-09 UniRef50_Q8YLL2 Cluster: Alr5286 protein; n=10; Cyanobacteria|Re... 64 2e-09 UniRef50_Q89WX4 Cluster: Short-chain dehydrogenase; n=11; Bradyr... 64 2e-09 UniRef50_Q829D6 Cluster: Putative dehydrogenase; n=2; Streptomyc... 64 2e-09 UniRef50_Q7VXT8 Cluster: Probable short-chain dehydrogenase; n=3... 64 2e-09 UniRef50_Q6N3Z0 Cluster: Putative short-chain dehydrogenase/redu... 64 2e-09 UniRef50_Q5NM60 Cluster: Short-chain alcohol dehydrogenase; n=14... 64 2e-09 UniRef50_Q1YP86 Cluster: Oxidoreductase; n=2; unclassified Gamma... 64 2e-09 UniRef50_Q12B22 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09 UniRef50_Q0SJT0 Cluster: Short chain dehydrogenase; n=13; Actino... 64 2e-09 UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09 UniRef50_A7NQP2 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09 UniRef50_A6LUV1 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09 UniRef50_A6GFU2 Cluster: Short chain dehydrogenase; n=1; Plesioc... 64 2e-09 UniRef50_A4XEH1 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09 UniRef50_A4QHZ4 Cluster: Putative uncharacterized protein; n=1; ... 64 2e-09 UniRef50_A4ALI9 Cluster: Putative short chain dehydrogenase; n=2... 64 2e-09 UniRef50_A0TVU3 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09 UniRef50_A0QGC5 Cluster: Sorbitol utilization protein SOU1; n=3;... 64 2e-09 UniRef50_Q0UTY3 Cluster: Putative uncharacterized protein; n=1; ... 64 2e-09 UniRef50_P46331 Cluster: Uncharacterized oxidoreductase yxbG; n=... 64 2e-09 UniRef50_P37079 Cluster: Sorbitol-6-phosphate 2-dehydrogenase; n... 64 2e-09 UniRef50_Q04520 Cluster: Acetoin(diacetyl) reductase; n=1; Raoul... 64 2e-09 UniRef50_UPI000023CB88 Cluster: hypothetical protein FG04599.1; ... 64 3e-09 UniRef50_Q8UHH7 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 64 3e-09 UniRef50_Q93QG5 Cluster: Cyclohexanol dehydrogenase; n=4; Bacter... 64 3e-09 UniRef50_Q70I08 Cluster: Putative ketoreductase; n=1; Streptomyc... 64 3e-09 UniRef50_Q1ZIL9 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 64 3e-09 UniRef50_Q0S4U3 Cluster: Dehydrogenase; n=2; Actinomycetales|Rep... 64 3e-09 UniRef50_Q029B5 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09 UniRef50_P94681 Cluster: Toluenesulfonate zinc-independent alcoh... 64 3e-09 UniRef50_A6X7S0 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09 UniRef50_A6ELE5 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09 UniRef50_A4XEP3 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09 UniRef50_A3UA16 Cluster: Acetoin(Diacetyl)reductase; n=6; Bacter... 64 3e-09 UniRef50_A3I0R2 Cluster: Short chain dehydrogenase; n=2; Bactero... 64 3e-09 UniRef50_A0YCW9 Cluster: Putative 3-oxoacyl-acyl carrier protein... 64 3e-09 UniRef50_A0R6X9 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte... 64 3e-09 UniRef50_A0LJK6 Cluster: Short-chain dehydrogenase/reductase SDR... 64 3e-09 UniRef50_Q9SBM0 Cluster: Wts2L; n=3; core eudicotyledons|Rep: Wt... 64 3e-09 UniRef50_Q0DM18 Cluster: Os03g0833100 protein; n=5; Oryza sativa... 64 3e-09 UniRef50_Q92A39 Cluster: Lin2083 protein; n=16; Bacilli|Rep: Lin... 64 4e-09 UniRef50_Q8KKW9 Cluster: Putative oxidoreductase protein; n=1; R... 64 4e-09 UniRef50_Q833Z8 Cluster: Short chain dehydrogenase; n=23; Bacill... 64 4e-09 UniRef50_Q7W386 Cluster: Short chain dehydrogenase; n=111; cellu... 64 4e-09 UniRef50_Q6MLJ7 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 64 4e-09 UniRef50_Q65F37 Cluster: Putative uncharacterized protein; n=1; ... 64 4e-09 UniRef50_Q5YNA7 Cluster: Putative short chain dehydrogenase; n=1... 64 4e-09 UniRef50_Q2RUY0 Cluster: Short-chain dehydrogenase/reductase SDR... 64 4e-09 UniRef50_O32291 Cluster: YxnA protein; n=4; Bacteria|Rep: YxnA p... 64 4e-09 UniRef50_Q41CM8 Cluster: Short-chain dehydrogenase/reductase SDR... 64 4e-09 UniRef50_Q1NCX9 Cluster: Putative uncharacterized protein; n=1; ... 64 4e-09 UniRef50_Q1DCG1 Cluster: Oxidoreductase, short-chain dehydrogena... 64 4e-09 UniRef50_Q13HC1 Cluster: Putative short-chain dehydrogenase/redu... 64 4e-09 UniRef50_Q12HD3 Cluster: Short-chain dehydrogenase/reductase SDR... 64 4e-09 UniRef50_Q11BT3 Cluster: Short-chain dehydrogenase/reductase SDR... 64 4e-09 UniRef50_Q0TM71 Cluster: Oxidoreductase, short chain dehydrogena... 64 4e-09 UniRef50_A6W9N2 Cluster: Short-chain dehydrogenase/reductase SDR... 64 4e-09 UniRef50_A3J2Q4 Cluster: Short-chain dehydrogenase; n=2; Flavoba... 64 4e-09 UniRef50_A3ET57 Cluster: Short-chain alcohol dehydrogenase; n=2;... 64 4e-09 UniRef50_A2U5Y6 Cluster: Short-chain dehydrogenase/reductase SDR... 64 4e-09 UniRef50_A0JVX6 Cluster: Short-chain dehydrogenase/reductase SDR... 64 4e-09 UniRef50_Q75QV9 Cluster: 17-beta hydroxysteroid dehydrogenase; n... 64 4e-09 UniRef50_Q14RS1 Cluster: ABA4 protein; n=4; Pezizomycotina|Rep: ... 64 4e-09 UniRef50_UPI00015B5DCD Cluster: PREDICTED: similar to oxidoreduc... 63 5e-09 UniRef50_UPI00015B452D Cluster: PREDICTED: similar to ENSANGP000... 63 5e-09 UniRef50_UPI000023F0AD Cluster: hypothetical protein FG09028.1; ... 63 5e-09 UniRef50_Q88T73 Cluster: Short-chain dehydrogenase/oxidoreductas... 63 5e-09 UniRef50_Q6NDJ6 Cluster: Putative 3-oxoacyl-(Acyl carrier ptn) r... 63 5e-09 UniRef50_Q6MR20 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 63 5e-09 UniRef50_Q65SP1 Cluster: FabG protein; n=10; Bacteria|Rep: FabG ... 63 5e-09 UniRef50_Q5FKH2 Cluster: Oxidoreductase, short chaindehydrogenas... 63 5e-09 UniRef50_Q2IVE1 Cluster: Short-chain dehydrogenase/reductase SDR... 63 5e-09 UniRef50_Q2BDF6 Cluster: Putative uncharacterized protein; n=1; ... 63 5e-09 UniRef50_Q1LG76 Cluster: Short-chain dehydrogenase/reductase SDR... 63 5e-09 UniRef50_Q0YP41 Cluster: Short-chain dehydrogenase/reductase SDR... 63 5e-09 UniRef50_Q0SJP8 Cluster: Short chain dehydrogenase; n=1; Rhodoco... 63 5e-09 UniRef50_A7IJ54 Cluster: Short-chain dehydrogenase/reductase SDR... 63 5e-09 UniRef50_A7DJ01 Cluster: Short-chain dehydrogenase/reductase SDR... 63 5e-09 UniRef50_A6DLZ1 Cluster: Glucose-1-dehydrogenase; n=1; Lentispha... 63 5e-09 UniRef50_A3W7Y7 Cluster: Putative uncharacterized protein; n=3; ... 63 5e-09 UniRef50_A3IBN0 Cluster: Predicted short chain dehydrogenase; n=... 63 5e-09 UniRef50_A3HUJ4 Cluster: NAD dependent epimerase/dehydratase fam... 63 5e-09 UniRef50_A0YDP4 Cluster: Short chain dehydrogenase; n=1; marine ... 63 5e-09 UniRef50_A0DCG9 Cluster: Chromosome undetermined scaffold_45, wh... 63 5e-09 UniRef50_Q4P1P4 Cluster: Putative uncharacterized protein; n=1; ... 63 5e-09 UniRef50_Q2UTV6 Cluster: Dehydrogenases with different specifici... 63 5e-09 UniRef50_Q07530 Cluster: Uncharacterized oxidoreductase YDL114W;... 63 5e-09 UniRef50_P16544 Cluster: Putative ketoacyl reductase; n=42; Bact... 63 5e-09 UniRef50_UPI000050F7E5 Cluster: COG1028: Dehydrogenases with dif... 63 6e-09 UniRef50_Q9A3M7 Cluster: Short chain dehydrogenase family protei... 63 6e-09 UniRef50_Q7UMF1 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 63 6e-09 UniRef50_Q7ULD3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 63 6e-09 UniRef50_Q7MAW1 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 63 6e-09 UniRef50_Q39N51 Cluster: Short-chain dehydrogenase/reductase SDR... 63 6e-09 UniRef50_Q39N07 Cluster: Short-chain dehydrogenase/reductase SDR... 63 6e-09 UniRef50_Q0S7P7 Cluster: Short chain dehydrogenase; n=7; Bacteri... 63 6e-09 UniRef50_Q0RWG5 Cluster: Probable short chain dehydrogenase; n=2... 63 6e-09 UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=... 63 6e-09 UniRef50_A7U537 Cluster: Short-chain dehydrogenase/reductase; n=... 63 6e-09 UniRef50_A6E9L8 Cluster: Putative uncharacterized protein; n=1; ... 63 6e-09 UniRef50_A6CW76 Cluster: Putative short chain dehydrogenase; n=1... 63 6e-09 >UniRef50_Q1G151 Cluster: Putative alcohol dehydrogenase; n=1; Bombyx mori|Rep: Putative alcohol dehydrogenase - Bombyx mori (Silk moth) Length = 274 Score = 173 bits (420), Expect = 4e-42 Identities = 84/199 (42%), Positives = 126/199 (63%), Gaps = 1/199 (0%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKFYRS 181 DKV +TG A G+G +V+ LL E +H+A LD+A+ G +L+ +L K+G + KF + Sbjct: 14 DKVFLVTGGAAGVGAGLVKALLFENARHVAFLDVADREGAALEAQLIIKFGALRVKFIKC 73 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361 DV +E V+ + +D VIN+AA+++ + + I++N T + STLKA++I Sbjct: 74 DVGDERQLASAYKQVLDKYKRLDGVINSAAVLSVDDNSFNRMIDINFTGTVNSTLKALDI 133 Query: 362 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTV 541 MG GG GG ++N+SS+ AL + +P+Y ATK+AVLQFS +G E F++T VRVL+V Sbjct: 134 MGADKGGSGGVIVNISSLLALNLTSHLPVYAATKAAVLQFSIRMGTQEQFTRTKVRVLSV 193 Query: 542 CFGATDTALLTDEKLGTFD 598 C G TDTA+L L FD Sbjct: 194 CLGPTDTAILYKNNLTKFD 212 >UniRef50_Q6RUR3 Cluster: Putative alcohol dehydrogenase; n=2; Neoptera|Rep: Putative alcohol dehydrogenase - Gryllotalpa orientalis (Oriental mole cricket) Length = 266 Score = 156 bits (379), Expect = 4e-37 Identities = 79/193 (40%), Positives = 117/193 (60%), Gaps = 1/193 (0%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 178 K K +TG ATGIG + V+ LL GV+ +A+ D+ E G + +LN ++G K F + Sbjct: 4 KGKYALVTGGATGIGLAYVKELLRHGVQAVAVADLDERKGDNSVKQLNDEFGAGKAIFIK 63 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 358 DVTN++ G+D+VINNA +++DS ++ I +NVTA+ T A + Sbjct: 64 CDVTNKDDLEATFRKAAATFKGLDIVINNAGILDDSR--WETEIAINVTAVARGTWLAFD 121 Query: 359 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538 +MGK+ GG+GG V+N++S+ L P+Y ATK AV+ S G P HF +TGVRVLT Sbjct: 122 LMGKNKGGRGGVVVNIASILGLQAMAGCPVYVATKHAVVGLSRSFGMPYHFDRTGVRVLT 181 Query: 539 VCFGATDTALLTD 577 +C G TDT L+++ Sbjct: 182 MCPGVTDTPLISE 194 >UniRef50_Q6NYE8 Cluster: Zgc:56585 protein; n=5; Clupeocephala|Rep: Zgc:56585 protein - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 270 Score = 154 bits (373), Expect = 2e-36 Identities = 81/208 (38%), Positives = 127/208 (61%), Gaps = 5/208 (2%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 178 KDKV +TGAA G+G S V IL+ G K +A++D+ + G+ L+ LN +YG N+ +FY Sbjct: 4 KDKVAVVTGAAQGLGRSFVEILMKNGSK-VALIDVNKSLGEELKTNLNKEYGPNRAEFYT 62 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 358 +DV++EE F G+L +V++ G ID++ NNA ++N+ ++K I +N+ ++ T A+E Sbjct: 63 ADVSSEEDFKGVLKKIVEQFGQIDIMCNNAGIINEKH--WEKTIAINLGGVVRGTYLALE 120 Query: 359 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538 M K +GG GG ++NV+S+A L V PIY ATK V+ FS + S GVR+ Sbjct: 121 YMKKENGGSGGVIVNVASMAGLGPLPVAPIYTATKHGVVGFSRAMAVVSKLSNYGVRINV 180 Query: 539 VCFGATDTALL----TDEKLGTFDKYLE 610 +C T+LL ++E G+F + E Sbjct: 181 LCPWFVKTSLLSLLNSEEHTGSFSQMKE 208 >UniRef50_UPI0000DB7440 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase; n=1; Apis mellifera|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase - Apis mellifera Length = 266 Score = 150 bits (364), Expect = 2e-35 Identities = 76/182 (41%), Positives = 117/182 (64%), Gaps = 1/182 (0%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 178 KDK V ITG A+G+G ++ R LL G IA++D AEE+GK LN ++G N+T FY Sbjct: 4 KDKRVIITGVASGLGLTISRELLRNGASIIAMID-AEESGKETVDILNKEFGRNRTIFYH 62 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 358 ++ N F V+ GG+++++NNA + N++ + K I+VNVT++I +TL I+ Sbjct: 63 CNIANNSEFDDTFKKAVKALGGLEILVNNADVTNETD--FMKTIDVNVTSVIRATLLGIQ 120 Query: 359 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538 M K GGKGG ++N+SS+A L + +P+Y ATK AV+ FS +P H+ +TGV++L Sbjct: 121 QMQKDLGGKGGAIVNISSLAGLYAAPQLPVYSATKHAVVSFSRSFAQPYHYKRTGVKILV 180 Query: 539 VC 544 +C Sbjct: 181 MC 182 >UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 261 Score = 143 bits (347), Expect = 3e-33 Identities = 71/191 (37%), Positives = 118/191 (61%), Gaps = 1/191 (0%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 +KV ITG A GIG ++V+ LL+ G+K +A+ D+ K + ++L KYGN+ + Y D Sbjct: 5 NKVAIITGGAGGIGAAIVKRLLEHGIKLVALFDLDNSNTKKIFMDLQKKYGNRVELYPCD 64 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK-AIEVNVTALITSTLKAIEI 361 VTN+ F + V++ ID+++NNA + +D I+ + I++N A++ +L IE Sbjct: 65 VTNKAQFEENFDKVLKTHKTIDILLNNAGIGSD---IHTELMIDLNYKAVVLGSLLFIER 121 Query: 362 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTV 541 +GKH GGKGG ++N +S+ L +P+Y +TK AV+ F+ C+ + TGVRV+ + Sbjct: 122 LGKHKGGKGGIIVNTASILGLRNFDCLPVYCSTKHAVVSFTRCL--DVQYDTTGVRVVAI 179 Query: 542 CFGATDTALLT 574 C G T+T L++ Sbjct: 180 CPGVTETPLVS 190 >UniRef50_UPI00015B5316 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 329 Score = 142 bits (343), Expect = 8e-33 Identities = 69/195 (35%), Positives = 115/195 (58%), Gaps = 1/195 (0%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 178 KDK + GA G+G + + LL GV + ++D+ E G++ LN ++G N+ F + Sbjct: 71 KDKKAMVIGACDGLGMAFSKELLRNGVARVLMIDMNETLGRAQADRLNEEFGRNRATFTK 130 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 358 DVT F V G +D+++NNAA++ D + ++ I+ NVTA+ +++ ++ Sbjct: 131 CDVTKGSEFDACFKDAVNTLGALDIIVNNAAMI-DEVNFHR-TIDTNVTAVFRASMMGVQ 188 Query: 359 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538 MGK +GGKGG ++NV+SV L +PIY AT AV+ FS +P H+ +TGVR++ Sbjct: 189 QMGKDTGGKGGVIVNVASVLGLEACPQLPIYSATNHAVIAFSRSFSQPYHYQRTGVRLMV 248 Query: 539 VCFGATDTALLTDEK 583 +C G T++ +L + K Sbjct: 249 LCPGLTESPMLENLK 263 >UniRef50_UPI00015B573D Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 279 Score = 141 bits (341), Expect = 1e-32 Identities = 75/205 (36%), Positives = 119/205 (58%), Gaps = 1/205 (0%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 178 KDKV+ +TG A GIG V L++G +++AILDI E +L ++G ++ Y Sbjct: 11 KDKVIIVTGGANGIGLECVLEFLEKGARYVAILDITPE--NFTADKLQEEFGTHRVDLYH 68 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 358 D+ NEE F V+++ +D++IN+A + N++ + ++VNV I L AIE Sbjct: 69 CDIANEEEFRSNFKKVIEKHNYVDILINDAGVANENDTA--RLLDVNVKGTILGNLMAIE 126 Query: 359 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538 MGKH GG+GG V+NV+SV L HV+P+Y A+K A++ F+ + + + GV+++ Sbjct: 127 HMGKHKGGRGGVVVNVASVIGLLNCHVLPVYSASKHAIVSFTRSM--KSNCDRLGVKIIA 184 Query: 539 VCFGATDTALLTDEKLGTFDKYLEF 613 VC G T T L + + T YL+F Sbjct: 185 VCPGHTRTKLNFELAVETSVNYLDF 209 >UniRef50_UPI0000513348 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase; n=2; Apis mellifera|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase - Apis mellifera Length = 263 Score = 140 bits (338), Expect = 3e-32 Identities = 73/200 (36%), Positives = 116/200 (58%), Gaps = 1/200 (0%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKFYR 178 K+K ITG G+G + LL+ G K +A+LD++ G+ L ++G K FY Sbjct: 6 KNKTALITGGTVGLGLIYAKRLLENGAKCVALLDLSSSPGQQTVNNLEKEFGKGKAIFYA 65 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 358 DV+N F + VV + G+D+VINNA + ND +++ + +NV +I +L A + Sbjct: 66 CDVSNINEFEAVFKKVVNDLNGLDIVINNAGIYNDKK--WEQTMCINVGGVIQGSLLAFD 123 Query: 359 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538 M K GGKGGT++N++S+ AL + P+Y A+K VL FS + R +++ TG+R+L Sbjct: 124 HMSKLKGGKGGTIVNIASIVALDIIYSNPVYCASKHFVLAFSRSLAR--YYNNTGIRILI 181 Query: 539 VCFGATDTALLTDEKLGTFD 598 +C G T T+LL + +FD Sbjct: 182 MCPGVTTTSLLENPLSKSFD 201 >UniRef50_UPI00015B4C63 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 271 Score = 138 bits (335), Expect = 8e-32 Identities = 71/199 (35%), Positives = 117/199 (58%), Gaps = 8/199 (4%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKFYRS 181 +KV+ ITG G+G + LL+ G K +A+ D+ E G+S +L+ ++G + FY Sbjct: 5 NKVIIITGGVGGMGFETAKALLNHGAKFVALFDLTETDGQSAIEKLDKEFGKGRAGFYPG 64 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALI-------TS 340 D+ + F N ++++ G IDV+INNA + N+ ++ + VNV + I + Sbjct: 65 DIVIDSEFEDNFNRIIKDHGSIDVLINNAGIANEQN--IERLVNVNVVSSIDKNILRASQ 122 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 L A+ MGKH GGKGG ++NV+++ L ++P Y ATK A++ F+ C+ E+F+ T Sbjct: 123 ILLALNHMGKHKGGKGGAIVNVNAILGLIDCPILPFYSATKHAIIGFTRCM--KENFATT 180 Query: 521 GVRVLTVCFGATDTALLTD 577 GVRV++VC G T T L+ + Sbjct: 181 GVRVMSVCPGVTKTNLIKE 199 >UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=3; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 273 Score = 131 bits (316), Expect = 2e-29 Identities = 66/190 (34%), Positives = 116/190 (61%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 KDKVV ITG +GIG S+ + +L G K++A+ ++ E + + EL+ +Y ++ FY Sbjct: 21 KDKVVVITGGTSGIGLSIAKHMLKNGAKYVALFELDHENSRIVFDELHKQYHDRIGFYPC 80 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361 DVT + + V++ ID++INNA + +D+ + ++++N+ AL+ ++ K I Sbjct: 81 DVTKTDLIYNNFDKVMESHKTIDILINNAGIADDNKP--ELSVDINLKALVVASYKFIAR 138 Query: 362 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTV 541 +GKH GGKGG ++N++S+A + S +P+Y ATK V+ F+ + + TGVRVL + Sbjct: 139 IGKHKGGKGGVIVNIASIAGIV-SGFLPVYCATKHGVVGFTRTL--QMSYGLTGVRVLAI 195 Query: 542 CFGATDTALL 571 C T+T ++ Sbjct: 196 CPSFTNTPIV 205 >UniRef50_UPI00015B42E2 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 266 Score = 131 bits (316), Expect = 2e-29 Identities = 71/193 (36%), Positives = 113/193 (58%), Gaps = 3/193 (1%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQV--ELNSKYG-NKTKF 172 KDKV +TG GIG + V+ LL G K++AI D+ ++ ++ ++G +K F Sbjct: 4 KDKVAIVTGGTGGIGFATVQALLRHGAKYVAIFDLDSMHTRAASCIHKVEEEFGKDKADF 63 Query: 173 YRSDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 352 Y DVT + F + +V Q +D+++N A++ ++ + I++N+TA++T TL Sbjct: 64 YTCDVTIQSEFAARYDEIVGMQRTVDILVNYASIASEPRAHHM--IDINLTAVVTCTLIG 121 Query: 353 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532 I+ MG+H G+GG ++NV SV LT S PIY ATK V F+ + +H+ GVRV Sbjct: 122 IDRMGRHHNGRGGAIVNVCSVFGLTTSPAFPIYTATKYGVYGFTKSL--KDHYEHLGVRV 179 Query: 533 LTVCFGATDTALL 571 + VC G T+T+LL Sbjct: 180 MAVCPGLTETSLL 192 >UniRef50_UPI00015B5A58 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 263 Score = 128 bits (310), Expect = 8e-29 Identities = 71/193 (36%), Positives = 115/193 (59%), Gaps = 3/193 (1%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKS-LQVE-LNSKYGN-KTKF 172 K+KV+ ITG G+ + ++LL ++IA+ D E+ + LQ++ ++G + F Sbjct: 4 KNKVIIITGGLGGLATATTQVLLKHEPRYIALFDTEEKNSYAELQLKKFEQEFGEGRVGF 63 Query: 173 YRSDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 352 Y SDV N+ F + V++ +D++IN A ++ D+ + I+VN L+ TL A Sbjct: 64 YASDVRNQHQFEEKYDQVLKSHKSVDILINLAGILCDADT--ELTIDVNFKGLVFCTLTA 121 Query: 353 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532 I+ MG H GG+GGT+INVSS+ L P+Y ATK AV+ F+N + H++KTGVR Sbjct: 122 IDKMGIHRGGRGGTIINVSSIVGLMFHEDFPVYVATKHAVVAFTNSL--KSHYAKTGVRA 179 Query: 533 LTVCFGATDTALL 571 +T+C G T T+++ Sbjct: 180 MTMCPGLTSTSMI 192 >UniRef50_UPI000051334A Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1) isoform 1; n=1; Apis mellifera|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1) isoform 1 - Apis mellifera Length = 264 Score = 128 bits (309), Expect = 1e-28 Identities = 62/188 (32%), Positives = 111/188 (59%), Gaps = 1/188 (0%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 184 K+ +TG A GIG R LL G K +A+LD+++ G+S +LN+++G ++ F D Sbjct: 6 KIAIVTGGANGIGFCTARKLLRNGAKAVALLDLSDSGGESAAADLNNEFGKDRAIFIACD 65 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 364 V+ E F V+ +++++N A +M+D+ ++ +++N ++ T+ + M Sbjct: 66 VSKNEQFQESFKKVIDTYETLNILVNIAGIMDDAD--WEIMVDINYKGIVYGTILGLHTM 123 Query: 365 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVC 544 GK+ GG GG ++N+SSVA L + PIY T+ A++ F+ + ++ KTG+R+LT+C Sbjct: 124 GKYKGGNGGIIVNMSSVAGLEGIPIAPIYGGTQYAIVGFTQSL--KHYYEKTGIRMLTIC 181 Query: 545 FGATDTAL 568 G T TA+ Sbjct: 182 PGLTTTAM 189 >UniRef50_UPI00015B5FC8 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 267 Score = 126 bits (303), Expect = 6e-28 Identities = 74/199 (37%), Positives = 117/199 (58%), Gaps = 4/199 (2%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE---EAGKSLQVELNSKYGNKT-K 169 K+KV +TG GIG V+ L+ ++ +AI+D+ + EA + +LN ++G + + Sbjct: 4 KNKVAIVTGGIGGIGLVTVQHLIRSKIQFVAIIDLPKSDSEAAVANLSKLNKEFGKGSYQ 63 Query: 170 FYRSDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 349 +Y D+TN + F I V+ + +D++IN A ++ND+ I VN TA++ S++ Sbjct: 64 YYSCDLTNIQEFRAIYEKVIALKKYVDILINAAGILNDNA--MNLCINVNFTAVVNSSMI 121 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 AIE M K GGKGG V+NV+S+A + PIY ATK AV+ F+ + +P H GVR Sbjct: 122 AIEHMRKDKGGKGGVVVNVASIAGIVDFPYNPIYNATKHAVVAFARSL-KP-HNKIIGVR 179 Query: 530 VLTVCFGATDTALLTDEKL 586 V+ +C G TDT L+ + L Sbjct: 180 VVCICPGVTDTGLVAFDHL 198 >UniRef50_UPI0000D57364 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1); n=1; Tribolium castaneum|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1) - Tribolium castaneum Length = 312 Score = 126 bits (303), Expect = 6e-28 Identities = 65/188 (34%), Positives = 107/188 (56%), Gaps = 1/188 (0%) Frame = +2 Query: 11 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 187 V ITG A GIG ++ R+ L G+ +A+ D ++E G+ +L ++G NK F+ D+ Sbjct: 54 VAIITGGAEGIGLAIARVFLKCGISGLAVADCSKEKGEESIKQLACEFGENKVLFFDGDM 113 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 367 + + F + + +++V+NNA +MND ++ + N++ I TL ++ M Sbjct: 114 SQSKAFDRVFKETLNHFENVNIVVNNAGVMNDVN--WECQVNTNLSGTIIGTLLGMQYMS 171 Query: 368 KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVCF 547 K S G+GGT+INV+S+ L S PI+ T+ ++ FS +G HF +TGVRV +C Sbjct: 172 KTSLGQGGTIINVASIMGLIPSSGYPIHTLTQFGIVGFSRAIGNLNHFDRTGVRVTALCP 231 Query: 548 GATDTALL 571 G T+T LL Sbjct: 232 GLTNTKLL 239 >UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|Rep: CG4899-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 278 Score = 124 bits (299), Expect = 2e-27 Identities = 64/193 (33%), Positives = 112/193 (58%), Gaps = 1/193 (0%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT-KFYR 178 + K +TG A GIG V + LL G +AI+D+ + + V+L + + ++ + Sbjct: 21 RGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEF--VKLRAAHPTQSVMIIK 78 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 358 DV N++ + + G ID+V+N A + ND ++ + VN+ +I STL A+ Sbjct: 79 MDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKD--VQRTLLVNLGGIINSTLSALP 136 Query: 359 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538 MGK +GGKGG V+N+SSV L ++P+Y ATK+ ++ F+ C+ +++ ++G++ +T Sbjct: 137 YMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSGIKFVT 196 Query: 539 VCFGATDTALLTD 577 VC GAT T + T+ Sbjct: 197 VCPGATMTDMFTN 209 >UniRef50_P15428 Cluster: 15-hydroxyprostaglandin dehydrogenase [NAD+]; n=29; Euteleostomi|Rep: 15-hydroxyprostaglandin dehydrogenase [NAD+] - Homo sapiens (Human) Length = 266 Score = 121 bits (292), Expect = 1e-26 Identities = 65/204 (31%), Positives = 115/204 (56%), Gaps = 2/204 (0%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 184 KV +TGAA GIG + LL +G K +A++D EAG + L+ ++ KT F + D Sbjct: 6 KVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 364 V +++ VV G +D+++NNA + N+ ++K +++N+ ++I+ T ++ M Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN--WEKTLQINLVSVISGTYLGLDYM 122 Query: 365 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVC 544 K +GG+GG +IN+SS+A L P+Y A+K ++ F+ + +GVR+ +C Sbjct: 123 SKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAIC 182 Query: 545 FGATDTALLTD-EKLGTFDKYLEF 613 G +TA+L EK +Y+E+ Sbjct: 183 PGFVNTAILESIEKEENMGQYIEY 206 >UniRef50_UPI0000E47587 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase (NAD+), partial; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase (NAD+), partial - Strongylocentrotus purpuratus Length = 298 Score = 121 bits (291), Expect = 2e-26 Identities = 67/193 (34%), Positives = 110/193 (56%), Gaps = 2/193 (1%) Frame = +2 Query: 11 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 187 V ITGAA G G++ LL V+ I I+D GK+ + ELN KYG +K +F++ DV Sbjct: 46 VALITGAAEGFGKAFTEELLKRSVRGIGIVDFNAAKGKATETELNKKYGEDKVRFFQCDV 105 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 367 ++++ + ++ GID+V NNA + D + ++K ++V++ A++ T A + M Sbjct: 106 SSKDQLEDAFSKTLEHYKGIDIVCNNAGI-GDELN-WEKTVDVDLVAVMRGTFLAKQYMD 163 Query: 368 KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEH-FSKTGVRVLTVC 544 K+ GG+GG VIN++S+A L + P Y A K VL FS + + F+ VR+ +C Sbjct: 164 KNKGGRGGIVINIASMAGLYPMPLAPAYSAAKHGVLGFSRALAIADKVFNPENVRLNCLC 223 Query: 545 FGATDTALLTDEK 583 ++TA+L K Sbjct: 224 PSFSETAILQQMK 236 >UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 337 Score = 120 bits (289), Expect = 3e-26 Identities = 62/191 (32%), Positives = 106/191 (55%), Gaps = 1/191 (0%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 184 K V ITG A G+G + L G I I+DI + AGK + + +G K F +D Sbjct: 46 KNVLITGGAAGLGHAFFNHFLQFGANKICIIDIDDVAGKKIVASTDKSHGVGKVIFIHAD 105 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 364 V+ + V+ +D+V+NNA ++++ +++ I VN+ +I+ L +++ M Sbjct: 106 VSRHSEIVAGFQKAVKLMDAVDIVVNNAGILDERR--WEREIAVNLNGMISVALLSMQYM 163 Query: 365 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVC 544 G+ GG+GG ++NV+ + + +P+Y ATK A++ S + P + +TGVRV+T+C Sbjct: 164 GRDMGGRGGILVNVAEHMDVHCTAQLPVYTATKQAIIGLSQSLAAPCNTERTGVRVITLC 223 Query: 545 FGATDTALLTD 577 G T+TAL D Sbjct: 224 PGLTETALTID 234 >UniRef50_Q1HPX6 Cluster: Alcohol dehydrogenase; n=1; Bombyx mori|Rep: Alcohol dehydrogenase - Bombyx mori (Silk moth) Length = 289 Score = 120 bits (288), Expect = 4e-26 Identities = 77/200 (38%), Positives = 107/200 (53%), Gaps = 3/200 (1%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 184 KVV ITGAA GIG ++ L G K I ILDI G ELN KYG NK +F D Sbjct: 34 KVVVITGAAQGIGYAIADNFLKNGAKVIIILDINVPKGIQAAKELNCKYGKNKAEFIECD 93 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 364 +T + I + ++ +DV++NNA + + +K + N A I +LK +E M Sbjct: 94 ITKDLE--RISKIIYKKYKYVDVLVNNAGIFKEIKP--RKLLLTNAVATIEFSLKFMENM 149 Query: 365 GKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTV 541 K GKGGT+IN++S P Y TK A++ FS +G ++ K GVRVLT+ Sbjct: 150 RKDKLSGKGGTIINIASTVVHYIDPFFPTYRGTKFAIMGFSRSLGHEYNYKKNGVRVLTI 209 Query: 542 CFGATDTAL-LTDEKLGTFD 598 C G T+T L L + K+ + D Sbjct: 210 CPGETNTTLGLDNTKVNSED 229 >UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to hydroxyprostaglandin dehydrogenase 15 (NAD); n=2; Tribolium castaneum|Rep: PREDICTED: similar to hydroxyprostaglandin dehydrogenase 15 (NAD) - Tribolium castaneum Length = 479 Score = 118 bits (284), Expect = 1e-25 Identities = 61/193 (31%), Positives = 108/193 (55%), Gaps = 2/193 (1%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKFYRS 181 +KV I+GAA+GIG ++ + LL G++ + I D+ +E G+ E+ +++G+ + F + Sbjct: 7 NKVALISGAASGIGLTIAKELLRNGLRGVTIADVNKELGEKALQEIENEFGSGRAIFVLT 66 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE- 358 DV++ + F + ID+++N A ++NDSI +++ I +NV + L A+E Sbjct: 67 DVSSMKSFEDAFQKTINTFKNIDILVNGAGVLNDSI--WQQEIAINVNGTVHGILLALEN 124 Query: 359 IMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538 + K+ G ++N SS+A + PIY TK A+ + G H+ +T VR++ Sbjct: 125 YIPKYKTDSEGVIVNFSSIAGVAAFPAFPIYTGTKFAIFGMTKAFGDEAHYERTKVRIMA 184 Query: 539 VCFGATDTALLTD 577 +C G TDT LL D Sbjct: 185 ICPGPTDTPLLRD 197 Score = 93.1 bits (221), Expect = 5e-18 Identities = 52/172 (30%), Positives = 91/172 (52%), Gaps = 2/172 (1%) Frame = +2 Query: 53 VVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDVTNEEHFLGILNAVV 229 +VR G + I DI E G+ + E+ +++G NK + +DVT + + + Sbjct: 233 IVRNAPSGGAWGVTIADINTELGEKVLQEIINEFGKNKAIYILTDVTCKNSYEAAFKKTI 292 Query: 230 QEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE-IMGKHSGGKGGTVINV 406 + +D+V+N A ++N+ +++ +++N+ + T+ A+E + K+ G G ++N+ Sbjct: 293 ETFQNLDIVVNGAGIVNELD--WQQEVDINLNGTLHGTILALENYIPKYKSGSEGVIVNI 350 Query: 407 SSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVCFGATDT 562 SS A L PIY TK AV+ S G H+ +T VRVLT C G T+T Sbjct: 351 SSAAILDCFPPYPIYTGTKFAVMGISKSFGAEVHYKRTKVRVLTACPGVTET 402 >UniRef50_Q7PY55 Cluster: ENSANGP00000013280; n=4; Endopterygota|Rep: ENSANGP00000013280 - Anopheles gambiae str. PEST Length = 183 Score = 117 bits (282), Expect = 2e-25 Identities = 66/183 (36%), Positives = 96/183 (52%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K+KV +TGAATG+G + LL G K + I D+ +AG+ EL +YG + F Sbjct: 4 KNKVALVTGAATGLGRAFSEELLKHGAK-VVICDLDSDAGELTVEELEKQYGARVLFCHC 62 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361 DVT+ F V +++VINNA +MND+ ++ ++VN+ I TL A + Sbjct: 63 DVTDYIQFEEAFEYTVNMFKEVNIVINNAEIMNDNF--WELEVDVNLNGAIRGTLLAQKF 120 Query: 362 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTV 541 M K G GG ++N+ S ++T PIY ATK A+L + G P H + T VR Sbjct: 121 MDKSKGKGGGVLVNIGSGVSVTPQLSTPIYTATKHAILGLTKACGDPFHHANTNVRAFAY 180 Query: 542 CFG 550 C G Sbjct: 181 CPG 183 >UniRef50_UPI0000D57365 Cluster: PREDICTED: similar to CG4899-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG4899-PA, isoform A - Tribolium castaneum Length = 295 Score = 114 bits (274), Expect = 2e-24 Identities = 64/191 (33%), Positives = 98/191 (51%), Gaps = 1/191 (0%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 184 KV ITG + GIG +V +L E K++A++ + G+ LNS YG NK F+ D Sbjct: 52 KVALITGGSDGIGLAVAHEILSENSKNVALIGVDNTKGRESVHALNSTYGRNKAVFFNCD 111 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 364 V ++ N V++E G ID+VIN A + + ++K I N+ I TL+A +M Sbjct: 112 VESKVQVNDCFNKVIKEFGSIDIVINAAGVFDGRC--WEKEIMTNLVGTIHCTLEAYRVM 169 Query: 365 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVC 544 K G GG ++N S + + P A+ ++ S G +F TGVRV+T+C Sbjct: 170 SKDCSGSGGVILNFSGLHGVKPLFPAPTLSASFHGIIGLSRSFGHETNFKTTGVRVVTLC 229 Query: 545 FGATDTALLTD 577 G T+T + D Sbjct: 230 PGITNTNFIKD 240 >UniRef50_UPI00015B572C Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 268 Score = 107 bits (256), Expect = 3e-22 Identities = 63/193 (32%), Positives = 104/193 (53%), Gaps = 5/193 (2%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIA----EEAGKSLQVELNSKYG-NKTK 169 +KV +TG GIG +V+ L G K +AI D+ EE +L+ +L ++ + Sbjct: 5 NKVGVVTGGLRGIGYVIVQHFLRRGAKFVAIFDLDVEEHEEVVNALK-QLEQEFAAQRFS 63 Query: 170 FYRSDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 349 +Y DVTN + F+ + V G +D+++NNA + + + VN T++I T+ Sbjct: 64 YYCCDVTNFKKFIACYDEVYTTNGAVDILVNNAGVFAEHD--QDLTVAVNFTSVIHCTMH 121 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 AIE MG + GGKGG ++ + S+ AL +P+Y ATK A+ F ++ +K GVR Sbjct: 122 AIERMGTNKGGKGGVIVTIGSICALISLSTIPVYSATKGALACFVR--STKDYNAKYGVR 179 Query: 530 VLTVCFGATDTAL 568 ++ +C G T T + Sbjct: 180 IVCLCPGMTKTKM 192 >UniRef50_Q9I7R3 Cluster: CG18814-PA; n=3; Sophophora|Rep: CG18814-PA - Drosophila melanogaster (Fruit fly) Length = 285 Score = 103 bits (248), Expect = 3e-21 Identities = 69/217 (31%), Positives = 113/217 (52%), Gaps = 18/217 (8%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS-D 184 K V G GIG+ V+ LL + +K +AI D+ + L E ++ + FY+ D Sbjct: 6 KNVVYLGGFGGIGKKCVQELLKKQIKGLAIFDLIVD--DDLLAEWKKQHPDTEIFYQKMD 63 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMND-----SIGIYKKAIEVNVT-------- 325 +T + A ++ G DVV+N + L++D +I I +E+ ++ Sbjct: 64 ITQKSDIDAAYKATAEKLGHFDVVVNGSGLLDDRRIELTIQINLVILEIVLSKGFIYQYF 123 Query: 326 ---ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVG 496 +I STL A+E M K GG+GG ++N+SSVA L + +M IY +K+ V F+ + Sbjct: 124 LKVGVINSTLTALEYMDKSKGGRGGLIVNISSVAGLQPTPLMAIYSTSKTGVTTFTRAMA 183 Query: 497 RPEHFSKTGVRVLTVCFGATDTALLTD-EKLGTFDKY 604 P H++ +GV +T+C G T+T +L D +K TF Y Sbjct: 184 SPIHYAHSGVGFITICPGYTNTGILKDIDKKTTFPFY 220 >UniRef50_UPI0000D5767E Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase; n=2; Tribolium castaneum|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase - Tribolium castaneum Length = 255 Score = 101 bits (241), Expect = 2e-20 Identities = 59/190 (31%), Positives = 102/190 (53%), Gaps = 1/190 (0%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K KV +TG A+GIG ++VR LL G+K ++++DI+E EL ++ F ++ Sbjct: 5 KGKVALVTGGASGIGLAMVRELLKNGIKAVSVVDISENT------ELQD---SRVTFIKT 55 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361 DVT ++ + V +D+V+NNA ++ D I +K+ I++N+ A+I T A+ Sbjct: 56 DVTCKKQLQAAFDKTVATYNQLDIVVNNAGVI-DEID-WKRTIDINLVAVIEGTYLALRT 113 Query: 362 -MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538 + K+ G ++N +SV L PIY +K V+ +G P + + VR++T Sbjct: 114 YLPKYKSEAEGVIVNTASVLGLCPLQSAPIYCTSKHGVVGLGRSLGGPHIYDEYKVRIVT 173 Query: 539 VCFGATDTAL 568 +C G DT + Sbjct: 174 ICPGLVDTPM 183 >UniRef50_Q9NAR7 Cluster: Alcohol dehydrogenase; n=23; Schizophora|Rep: Alcohol dehydrogenase - Bactrocera oleae (Olive fruit fly) Length = 258 Score = 96.7 bits (230), Expect = 4e-19 Identities = 59/188 (31%), Positives = 100/188 (53%), Gaps = 2/188 (1%) Frame = +2 Query: 11 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--KSLQVELNSKYGNKTKFYRSD 184 VVF+ G IG + ++ + V + D+ E A K+LQ +N K K + + D Sbjct: 8 VVFVGGLGF-IGYEACKQIMTKNVASFFVFDVLENAENIKALQA-INPK--TKVYYTKFD 63 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 364 +TN+ V+ + IDV++N A ++ D + + +N+ LI +TL+AI +M Sbjct: 64 ITNKASIKSAFADVIAKVQYIDVLVNGAGILTDPN--VELTMNINLIGLINTTLEAIPLM 121 Query: 365 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVC 544 K+ G+GG ++N++SV L + IY A+K V+ FS + P +++ TG+ V T C Sbjct: 122 DKNKKGRGGLIVNIASVLGLEPAPPAAIYCASKFGVMGFSRSISDPYYYNLTGIAVATFC 181 Query: 545 FGATDTAL 568 G T+T L Sbjct: 182 PGLTETPL 189 >UniRef50_Q5P8S6 Cluster: Putative dehydrogenase; n=4; Proteobacteria|Rep: Putative dehydrogenase - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 267 Score = 96.3 bits (229), Expect = 5e-19 Identities = 65/204 (31%), Positives = 105/204 (51%), Gaps = 10/204 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +++GAA+GIG ++ R+ EG + + D+ E G+++ + + G + F DV Sbjct: 8 KVAYVSGAASGIGAAIARVFAAEGAS-VLLGDVQVERGETVAAHIREQ-GGRALFIHHDV 65 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLK 349 ++E + L V+E GG+D+++NNA L + + K + VNV +I Sbjct: 66 SDERQWESALACAVEEFGGMDLLVNNAGIEQTGLLADVELADINKLLAVNVAGVILGHKH 125 Query: 350 AIEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 AI M S GKGG++IN+SSVA L + + +Y ATK AV S G+ Sbjct: 126 AIRTMRPGGSAGKGGSIINLSSVAGLIGTPALGVYSATKGAVRLLSKAAAVECGRLGYGI 185 Query: 527 RVLTVCFGATDTAL---LTDEKLG 589 RV ++ G DT + L D+ +G Sbjct: 186 RVNSIHPGLVDTDMGVKLVDDFVG 209 >UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR; n=10; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 282 Score = 93.9 bits (223), Expect = 3e-18 Identities = 59/211 (27%), Positives = 106/211 (50%), Gaps = 8/211 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 +V +TG A+GIG V + EG K + I D+ +E G++L + G F+ +DV Sbjct: 12 RVAIVTGGASGIGRGVAERFVAEGAK-VVIADVQDELGEALAEQC----GPNALFHHTDV 66 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA--------LMNDSIGIYKKAIEVNVTALITST 343 ++E +++ V+ G +DV++NNA L N+ + + + + VN+ +++ T Sbjct: 67 GDQEQMRRLVDVAVERFGALDVMVNNAGISSPLRRGLFNEDLEEFDRVMRVNLLSVMAGT 126 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 A M +H GG ++IN+SS+ + +P+Y A+K+A+L F+ C + Sbjct: 127 RDAGRYMSEHGGG---SIINLSSIGGIQAGGGVPVYRASKAAILHFTKCAA--IELAHYD 181 Query: 524 VRVLTVCFGATDTALLTDEKLGTFDKYLEFF 616 +RV + G T +L G + LE F Sbjct: 182 IRVNCIAPGNIPTPILQSSATGEDRERLEKF 212 >UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 266 Score = 93.5 bits (222), Expect = 4e-18 Identities = 61/194 (31%), Positives = 100/194 (51%), Gaps = 7/194 (3%) Frame = +2 Query: 11 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 187 V +TG GIG ++ + LLD K + +LDI E+ G L+ Y ++ F + DV Sbjct: 7 VAIVTGGVQGIGLAISKALLDRDGK-VCMLDINEKTGNETLKLLSENYSKHRVLFIKCDV 65 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALM---NDSI--GIYKKAIEVNVTALITSTLKA 352 T++ G +D++ NNA + ND + G +K I++NV +I TL Sbjct: 66 TSQPQMEAAFQRTKDVFGRLDILCNNAGIAVRENDLLRSGAWKTIIDINVKGVILGTLLG 125 Query: 353 IEIMGKHSG-GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 ++ MG G GGT++NV+S+A L + P+Y A+K AV+ + + ++ VR Sbjct: 126 LDHMGVSGAKGHGGTIVNVASLAGLVPAPASPVYTASKHAVVGLTRTL--TSLWATECVR 183 Query: 530 VLTVCFGATDTALL 571 V +C TDTA++ Sbjct: 184 VNCICPSFTDTAMV 197 >UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=16; Bacillaceae|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Bacillus anthracis Length = 264 Score = 93.1 bits (221), Expect = 5e-18 Identities = 69/217 (31%), Positives = 110/217 (50%), Gaps = 7/217 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 ++KV+ ITGA++GIGE V + ++G + ++ EE K+L ++ Y +Y Sbjct: 6 QNKVIVITGASSGIGEQVAMQVAEQGATPV-LMARTEEKLKALADKIKETYNTPCYYYVL 64 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITST 343 DV+ E + + V+QE G ID+++NNA + S+ K +VNV L+ T Sbjct: 65 DVSEETEVQSVFSKVLQEVGRIDILVNNAGFGIFKTFEDASMDEVKDMFQVNVFGLVACT 124 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 + M K + G +IN++S+A + Y ATK AVL F+N + R E S T Sbjct: 125 KAVLPYMVKRNEGH---IINIASLAGKIATPKSSAYAATKHAVLGFTNSL-RME-LSSTN 179 Query: 524 VRVLTVCFGATDTALL-TDEKLGTFDKYLEFFMLGPT 631 V V + G DT ++ GT+ K + +ML PT Sbjct: 180 VFVTAINPGPIDTNFFEIADQSGTYVKNMGRYMLKPT 216 >UniRef50_A6YPS8 Cluster: Oxidoreductase; n=1; Triatoma infestans|Rep: Oxidoreductase - Triatoma infestans (Assassin bug) Length = 252 Score = 93.1 bits (221), Expect = 5e-18 Identities = 66/195 (33%), Positives = 104/195 (53%), Gaps = 8/195 (4%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 KD+V +TGA+ GIGE++ R L + G+K +A L + + LQ + N+ G+ K Y+ Sbjct: 5 KDRVAVVTGASAGIGEAIARALAEHGMK-VAALARRLDRLQKLQDDCNNFIGS-IKPYKC 62 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAAL-----MND-SIGIYKKAIEVNVTALITST 343 DVTNE + ++V + G I V++NNA L M D S G ++ E NV L+T T Sbjct: 63 DVTNETEIATTIKSIVSDLGPISVLVNNAGLYENVPMTDTSQGSCRQTYETNVIGLVTFT 122 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVA--ALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSK 517 +EIM KH+ G +IN++S+A + M Y A+K AV + + K Sbjct: 123 QHVVEIMKKHN-ITDGHIININSLAGHVIIPKPGMANYTASKHAVTVLTESLKNELAAMK 181 Query: 518 TGVRVLTVCFGATDT 562 + +RV ++ G +T Sbjct: 182 SKIRVTSISPGLVNT 196 >UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Methanospirillum hungatei JF-1|Rep: Short-chain dehydrogenase/reductase SDR - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 249 Score = 92.7 bits (220), Expect = 7e-18 Identities = 62/214 (28%), Positives = 107/214 (50%), Gaps = 6/214 (2%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 ++KV+ +TG + GIG+++ DEG K + + EE+ K++ E++ K G+ ++ Sbjct: 6 ENKVLLVTGGSRGIGKAIALRCADEGAKVVITWESHEESAKNVVNEIHHKNGSAMAI-QA 64 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE------VNVTALITST 343 DV NE+ ++N + E G +D+++NNA +M +++ + K E N + Sbjct: 65 DVRNEDDVKKVINKIKGEYGRLDILVNNAGIMKNNLLLMTKTEEFDLLLATNCKGPFLYS 124 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 A ++M KH K G +IN+SSV + S +Y ATKS ++ F+ + + G Sbjct: 125 RAAAKLMLKH---KSGRIINISSVVGVYGSKGQSVYSATKSFLIAFTKSLAK--ELGPFG 179 Query: 524 VRVLTVCFGATDTALLTDEKLGTFDKYLEFFMLG 625 + V + G DT L D K T L LG Sbjct: 180 ITVNAIAPGFIDTDLTHDVKDETRQDLLSHIPLG 213 >UniRef50_Q9ABI1 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=7; Alphaproteobacteria|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Caulobacter crescentus (Caulobacter vibrioides) Length = 261 Score = 92.3 bits (219), Expect = 9e-18 Identities = 55/162 (33%), Positives = 89/162 (54%), Gaps = 7/162 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-YRSD 184 K FITG A G+G + R+L EG K +A+ DI +++ E+N+ +G T F + D Sbjct: 11 KKAFITGGAQGLGAAAGRMLAKEGAK-VALADINLAGAQAVADEINAAHGAGTAFAFELD 69 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTL 346 VT E+ ++ +L GG+ V++NNA + D G++KK + VNV ++ Sbjct: 70 VTQEDQWIDVLEKATAAMGGLSVLVNNAGIGGDGPIESLDFGLWKKVMSVNVDSVFLGAK 129 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 472 A+ M H + G++IN+SS+A L + P Y A+K+AV Sbjct: 130 HALTHMRAH---QPGSIINLSSIAGLIANGNSPAYNASKAAV 168 >UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1; Planctomyces maris DSM 8797|Rep: Probable putative oxidoreductase - Planctomyces maris DSM 8797 Length = 270 Score = 91.9 bits (218), Expect = 1e-17 Identities = 61/195 (31%), Positives = 94/195 (48%), Gaps = 3/195 (1%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 +D+VV +TG + GIGE R+ EG H+AIL AG+ L ELN K F + Sbjct: 19 QDRVVIVTGGSKGIGEGCSRVFCAEG-GHVAILARGLHAGQDLARELNETGPGKAMFVQC 77 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTAL---ITSTLKA 352 DV E ++ VV++ G +D +INNA + ++ + + +IE + ST Sbjct: 78 DVGEHEQIRSAIDLVVEQFGRLDCIINNAGVHPPAMSLEETSIEEMEQLMRVNFLSTFAG 137 Query: 353 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532 + H GT+IN+SS+ A+ H Y +TK A + F+ + + GVRV Sbjct: 138 AKYALPHLRKTKGTIINMSSMTAVLGQHHSTAYCSTKGAQVSFTKSLA--IELGEAGVRV 195 Query: 533 LTVCFGATDTALLTD 577 + DT L+ D Sbjct: 196 NAILPSNIDTPLMRD 210 >UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase family protein; n=4; cellular organisms|Rep: Short-chain dehydrogenase/reductase family protein - Gramella forsetii (strain KT0803) Length = 249 Score = 91.1 bits (216), Expect = 2e-17 Identities = 66/204 (32%), Positives = 104/204 (50%), Gaps = 9/204 (4%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K K + ITGA++GIGE+ L EGV ++ + EE K L+ +++ + G K Sbjct: 4 KGKTIIITGASSGIGEATAMRLAKEGV-NVVLTARREEKLKELKSKIDKENGGKALVIPG 62 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITST 343 DVT +E F +++ +E G ID +INNA LM N + K ++VN+ ++ Sbjct: 63 DVTKKEDFKNLIDKTKKEFGSIDGLINNAGLMPLSYVKNLHTDEWDKMVDVNIKGVLNGV 122 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 + M + K G +IN+SS AA +Y ATKSAV FS + R E K Sbjct: 123 AAVLPTMMEQ---KSGNIINISSSAARKIYPGGAVYCATKSAVKMFSEGL-RQELAPKFN 178 Query: 524 VRVLTVCFGATDTAL---LTDEKL 586 + + ++ G DT L +TD+++ Sbjct: 179 INITSIEPGFVDTELTDTITDDEI 202 >UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: Oxidoreductase - Oceanobacillus iheyensis Length = 244 Score = 90.2 bits (214), Expect = 4e-17 Identities = 59/198 (29%), Positives = 100/198 (50%), Gaps = 6/198 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 +DKV ITG +GIG + ++ EG K I ++D+ EE G S++ EL S+ G++ F ++ Sbjct: 4 QDKVAVITGGVSGIGAATAKLFASEGAKLI-LVDMNEEKGASIEAELKSQ-GSEAIFIKA 61 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 343 DVTNEE I + G +D++ NNA + + ++K +EV++ + Sbjct: 62 DVTNEEQVKNIYTTAIDTFGKVDILFNNAGIGAVKPTEELTYAEWRKTVEVDLDGVFLVA 121 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 AI+ K G ++N +S+ S Y A K+ V+ + +G ++ Sbjct: 122 QAAIKEFLK---AGSGVIVNTASMYGWVGSPGSAAYNAAKAGVVNLTRSLGL--EYAARN 176 Query: 524 VRVLTVCFGATDTALLTD 577 +RV +C G DTA+L D Sbjct: 177 IRVNALCPGFIDTAILGD 194 >UniRef50_Q5TWK5 Cluster: ENSANGP00000025423; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000025423 - Anopheles gambiae str. PEST Length = 191 Score = 89.8 bits (213), Expect = 5e-17 Identities = 54/184 (29%), Positives = 94/184 (51%), Gaps = 1/184 (0%) Frame = +2 Query: 20 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTNEE 199 + G G+G ++ + LL +GVK + I+D+ E +L S D++N Sbjct: 10 VFGGCGGMGMAIGQHLLRQGVKKLCIVDVVELTDSNLSCLKESGRDALILCKICDISNRA 69 Query: 200 HFLGILNAVVQEQ-GGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKHS 376 +L + E G ID+++N+A ++ + K I T +I S L A+ +M + Sbjct: 70 ALKQLLERDISEALGSIDILVNSAGIVESEVP--DKLIG---TGVINSCLIALNLMSRAK 124 Query: 377 GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVCFGAT 556 GGKGG ++NV+S A L +P Y A+K ++ F+ +G +S+TGV+ + +C G T Sbjct: 125 GGKGGVIVNVASTAGLEPIPFLPTYCASKHGLIGFTRSLGVEPVYSETGVKFIIICPGGT 184 Query: 557 DTAL 568 T + Sbjct: 185 RTRM 188 >UniRef50_Q6C6W8 Cluster: Similar to tr|Q9WYD3 Thermotoga maritima TM0297 Oxidoreductase; n=7; Ascomycota|Rep: Similar to tr|Q9WYD3 Thermotoga maritima TM0297 Oxidoreductase - Yarrowia lipolytica (Candida lipolytica) Length = 291 Score = 88.6 bits (210), Expect = 1e-16 Identities = 60/195 (30%), Positives = 102/195 (52%), Gaps = 8/195 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TG A G+G S+ L G+K IAILD+ ++ G +L+ YG + +FY++DV Sbjct: 46 KVAIVTGGARGLGFSMAEGLCSVGLKGIAILDVQQDLGLDAIEKLHKAYGVQAQFYKADV 105 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 349 +EE I++ VV + G +DVV+N+A + + +++ I++N+ T Sbjct: 106 RDEESVNEIIDRVVHDLGSVDVVVNSAGVADLVHAAEYPADKFRRVIDINLNGSFLVTQA 165 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMP--IYFATKSAVLQFSNCVGRPEHFSKTG 523 A M K G GGTV+ ++S++ + P Y A+K+AV S + ++ Sbjct: 166 AARHMIKQ--GTGGTVVFIASMSGSIVNWPQPQSAYNASKAAVKHLSKSLA--AEWAVHN 221 Query: 524 VRVLTVCFGATDTAL 568 +R ++ G DTAL Sbjct: 222 IRCNSISPGYMDTAL 236 >UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Flavobacterium johnsoniae UW101|Rep: Short-chain dehydrogenase/reductase SDR - Flavobacterium johnsoniae UW101 Length = 269 Score = 87.4 bits (207), Expect = 3e-16 Identities = 61/190 (32%), Positives = 100/190 (52%), Gaps = 6/190 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKY-GNKTKFYR 178 KDK + ITG TGIG+++ +L+ G + + I E+ K+ ++ ++ G++ Sbjct: 30 KDKKIVITGGTTGIGKAIADVLVSLGGR-VLIFGRDEKDFKNAVADIQKQFPGSEVYGTP 88 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAAL-----MNDSIGIYKKAIEVNVTALITST 343 +DVT +E IL E GGID++INNAAL N+S YK I+ N+T + Sbjct: 89 ADVTKKEDIQKILEIADNELGGIDILINNAALGAPGITNESYDDYKYIIDTNITGYLAFA 148 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 +A M + K G +IN+ S++A ++ IY ATKSA+ FS + + + G Sbjct: 149 QEAASRMKQQ---KSGHIINIGSMSAESKEAKSTIYVATKSAIRGFSTSLRK--ELNPLG 203 Query: 524 VRVLTVCFGA 553 ++V + GA Sbjct: 204 IKVSLIEPGA 213 >UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillus sp. B14905|Rep: Short chain dehydrogenase - Bacillus sp. B14905 Length = 252 Score = 87.0 bits (206), Expect = 3e-16 Identities = 56/195 (28%), Positives = 96/195 (49%), Gaps = 7/195 (3%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 +K+ +TGA +GIG + L G K + I+D +E G+ ++L + G + F ++D Sbjct: 5 NKIAVVTGAGSGIGRASSLKLASNGAK-VVIVDFNKETGEET-LKLVKEQGGEGIFVQAD 62 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITST 343 V+ E +NA V+ G IDV NNA ++ + Y + + +NV + Sbjct: 63 VSKSEDVEKYVNAAVETYGRIDVFFNNAGVIQKISPLTEIADSEYDRIMSINVKGVFLGL 122 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 I++M G G++IN +S A + H M +Y A+K AV+ + + K G Sbjct: 123 KHVIKVM---EGQGSGSIINTASTAGVRSEHSMAVYSASKHAVIGLTKSASL--EYVKKG 177 Query: 524 VRVLTVCFGATDTAL 568 +R+ +C G +TAL Sbjct: 178 IRINAICPGGVETAL 192 >UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=2; Actinomycetales|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Mycobacterium avium (strain 104) Length = 250 Score = 86.6 bits (205), Expect = 4e-16 Identities = 56/189 (29%), Positives = 101/189 (53%), Gaps = 4/189 (2%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TGAA+GIGE+ + L ++G K + + DI E+ G+ + E+ ++ G + F R+D+ Sbjct: 6 KVAVVTGAASGIGEATAKRLAEDGAK-VVVADINEDGGERVVAEI-AERGGEAAFLRTDI 63 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEV--NVTAL-ITSTLKAIE 358 + EE +++ V GG+ + NNAA+ + +++ + +V VT + + T + Sbjct: 64 SIEEDVNSLIDFAVSTYGGLHLAHNNAAVAHTPTPLHELSTDVFDTVTGIGLRGTFFCMR 123 Query: 359 IMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535 H G GG ++N +S AAL + M Y ATK ++ + G +++ G+RV Sbjct: 124 AEIAHMIGHGGGAIVNTASGAALKAAAGMHAYVATKHGIVGLTRNAGL--DYARNGIRVN 181 Query: 536 TVCFGATDT 562 V G+ T Sbjct: 182 AVAPGSIKT 190 >UniRef50_Q2W431 Cluster: Dehydrogenase with different specificities; n=2; Magnetospirillum|Rep: Dehydrogenase with different specificities - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 248 Score = 85.8 bits (203), Expect = 8e-16 Identities = 65/212 (30%), Positives = 104/212 (49%), Gaps = 6/212 (2%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 +DKV ITG A+GIG V+ + + G + I DI EAG+ EL +K G K +F R Sbjct: 4 EDKVALITGGASGIGYCTVKSMAELGA-DVLIADINVEAGEKAAAELTAK-GFKAEFVRL 61 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 343 DVT++ + + VV +G +D++ N A +++ K + +N+T I Sbjct: 62 DVTDKANIARVKEHVVATRGRLDILCNVAGWGHIQPFVDNDDAFIAKVMSLNLTGPIELI 121 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 +M + GK ++NV+S A S +Y A K ++ FS + R ++ Sbjct: 122 RAFFPLMIEKKTGK---IVNVASDAGRVGSLGESVYSAAKGGLIAFSKALAR--EGARFN 176 Query: 524 VRVLTVCFGATDTALLTDEKLGTFDKYLEFFM 619 + V +C G TDT LL E +K+LE F+ Sbjct: 177 INVNAICPGPTDTPLLKSEP----EKFLEAFL 204 >UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Short-chain dehydrogenase/reductase SDR precursor - Herpetosiphon aurantiacus ATCC 23779 Length = 247 Score = 85.8 bits (203), Expect = 8e-16 Identities = 57/195 (29%), Positives = 103/195 (52%), Gaps = 7/195 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TG A GIG + ++L +G + I DI E+ G + ++ G + F DV Sbjct: 5 KVAIVTGGAIGIGAATAQLLAKQGAI-VVIGDINEQTGLATVEQIRGNAG-QAYFRHCDV 62 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALITSTL 346 ++E ++ + +QGG+D++INNA + ++ ++ +++++T + Sbjct: 63 SHEADIQALVQFAL-DQGGLDIMINNAGIGGKPAPLHLTENHNWQRVLDIDLTGVFWGQK 121 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 A + M +GGKGG ++NV+S+A + S + Y K+ V+Q S G E + G+ Sbjct: 122 YASQAM--LAGGKGGAIVNVASIAGVAGSPNLGPYGVAKAGVIQMSK-TGAIE-LASAGI 177 Query: 527 RVLTVCFGATDTALL 571 R+ VC G T+TA+L Sbjct: 178 RINAVCPGWTETAIL 192 >UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reductase; n=7; Bacteria|Rep: 3-ketoacyl-acyl carrier protein reductase - Leptospira interrogans Length = 254 Score = 85.4 bits (202), Expect = 1e-15 Identities = 60/203 (29%), Positives = 100/203 (49%), Gaps = 6/203 (2%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K K +TGAA GIG+S L G ++ I D+ EE+ K+ E++ + G K + Sbjct: 5 KGKNAVVTGAARGIGKSTALTLAKAGA-NLVIADLNEESSKATADEISKQTGVKAIGIGT 63 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK------AIEVNVTALITST 343 +V++ + + A V E G +D+++NNA + D++ + K I VN+T T Sbjct: 64 NVSDVDSAAKAIQACVDEFGSVDILVNNAGITKDTLLMRMKKEQWDAVIAVNLTGTFNCT 123 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 AI+ M K+ GG++IN+SS+A + + Y A+K+ V+ F+ V K Sbjct: 124 QAAIKFMMKNP--NGGSIINLSSIAGVNGNIGQTNYSASKAGVIGFTKAVALEMASRKVR 181 Query: 524 VRVLTVCFGATDTALLTDEKLGT 592 + F AT+ EK+ T Sbjct: 182 CNAIAPGFIATEMTDAIPEKIRT 204 >UniRef50_Q89M15 Cluster: Dehydrogenase; n=3; Proteobacteria|Rep: Dehydrogenase - Bradyrhizobium japonicum Length = 271 Score = 85.4 bits (202), Expect = 1e-15 Identities = 56/194 (28%), Positives = 101/194 (52%), Gaps = 7/194 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TG A+GIGE++V + EG IA D+ E G L + +K G K F DV Sbjct: 10 KVALVTGGASGIGEAIVELFAREGATVIA-TDVDELRGPELAKRI-TKAGGKAIFLEQDV 67 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNA-------ALMNDSIGIYKKAIEVNVTALITSTL 346 ++EE ++ I+ + + G +D++++NA ++++ ++G ++K +N+ + S Sbjct: 68 SSEERWIEIVAEIAKRYGRLDIMVSNAGIGIAVPSIVDMTLGDWRKQNAINLDGVFLSVK 127 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 + +M K GG+++ +SS+A L + + Y ATK V F+ + G+ Sbjct: 128 HCLPLMRKTG---GGSIVMMSSLAGLRGAPGLSAYSATKGGVRLFAKSIAMECAAVGDGI 184 Query: 527 RVLTVCFGATDTAL 568 RV +V G DT + Sbjct: 185 RVNSVHPGIIDTPI 198 >UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=3; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Pyrococcus furiosus Length = 260 Score = 85.4 bits (202), Expect = 1e-15 Identities = 58/201 (28%), Positives = 102/201 (50%), Gaps = 6/201 (2%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K+KV +TG GIG ++ ++ + G K + + +I EEAG + L + G F ++ Sbjct: 7 KNKVAIVTGGGQGIGAAIAQLFAENGAK-VVLAEIDEEAGLEREAMLRER-GLDVTFIKT 64 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITST 343 DV +EE ++ V+ GG+D+++NNAA+M+ ++ +++ I VN+T + Sbjct: 65 DVADEESVKNMVKKTVELYGGVDILVNNAAIMSVKSIFERTLEEWERVIRVNLTGPYICS 124 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 A E M K GG +IN++S AL Y A+K +L ++ + +K Sbjct: 125 RYAAEEMIKRG---GGVIINIASTRALMSEPDTEPYSASKGGLLALTHSLA--ISLAKYR 179 Query: 524 VRVLTVCFGATDTALLTDEKL 586 +RV+ V G +T+ KL Sbjct: 180 IRVVAVSPGWIETSRWKKSKL 200 >UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Sphingomonadales|Rep: Short-chain dehydrogenase/reductase SDR - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 285 Score = 85.0 bits (201), Expect = 1e-15 Identities = 59/189 (31%), Positives = 90/189 (47%), Gaps = 4/189 (2%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TGAA+GIG++ V L EG H+ DI E G++L N + F R DV Sbjct: 6 KVAVVTGAASGIGKATVLKLAGEGA-HVFAADIDEAGGRALADASNGRID----FVRCDV 60 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK---KAIEVNVTALITSTLKAIE 358 T +++A + GGID+V NNAA D I + + + + ++ S I Sbjct: 61 TVPSDIEALMDAAAAKAGGIDIVFNNAAAGGDRAPIDEITPEGWDATMDLVLKSVAMGIR 120 Query: 359 IMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535 H G KG +++N +SVAAL + Y K+ VL + ++ G+RV Sbjct: 121 YAAPHMKGRKGASIVNTASVAALGAGYSPTAYAVAKAGVLHLTRVAA--TDLAQYGIRVN 178 Query: 536 TVCFGATDT 562 +C G +T Sbjct: 179 AICPGFINT 187 >UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 251 Score = 84.6 bits (200), Expect = 2e-15 Identities = 61/203 (30%), Positives = 98/203 (48%), Gaps = 6/203 (2%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV ITG A G GE+ R + EG + + I D+ +EAG+ + EL G+ +F DV Sbjct: 7 KVALITGGARGQGEAEARRFVAEGAR-VVIADVLDEAGQRVAAEL----GDAARFQHLDV 61 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 349 T E + ++A + + G +D+++NNAA++ S+ Y+K I+VN Sbjct: 62 TREADWQIAVDATLAQFGRLDILVNNAAILKLVPIEACSLDDYRKVIDVNQVGCWLGMKS 121 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 A +G GG+++NVSS A + Y ++K AV + F + G+R Sbjct: 122 A---LGALKAAGGGSIVNVSSTAGMEGVAGGSAYVSSKFAVRGMTKAAAL--EFGRYGIR 176 Query: 530 VLTVCFGATDTALLTDEKLGTFD 598 V +V G DT + + FD Sbjct: 177 VNSVHPGGIDTVMARPPEFADFD 199 >UniRef50_P91615 Cluster: Alcohol dehydrogenase-related 31 kDa protein; n=44; Drosophiliti|Rep: Alcohol dehydrogenase-related 31 kDa protein - Drosophila melanogaster (Fruit fly) Length = 272 Score = 83.8 bits (198), Expect = 3e-15 Identities = 56/194 (28%), Positives = 95/194 (48%), Gaps = 1/194 (0%) Frame = +2 Query: 38 GIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTN-EEHFLGI 214 GI ++L+ + + +AIL E Q++ + K + F+ DVT E Sbjct: 17 GIALETSKVLMTKNIAKLAILQSTENPQAIAQLQ-SIKPSTQIFFWTYDVTMAREDMKKY 75 Query: 215 LNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKHSGGKGGT 394 + V+ + IDV+IN A L +++ I N+T ++ + + M + GG GG Sbjct: 76 FDEVMVQMDYIDVLINGATLCDENN--IDATINTNLTGMMNTVATVLPYMDRKMGGTGGL 133 Query: 395 VINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVCFGATDTALLT 574 ++NV+SV L S V Y A+K V+ F+ + P ++S+ GV V+ VC G T + Sbjct: 134 IVNVTSVIGLDPSPVFCAYSASKFGVIGFTRSLADPLYYSQNGVAVMAVCCG--PTRVFV 191 Query: 575 DEKLGTFDKYLEFF 616 D +L F +Y + F Sbjct: 192 DRELKAFLEYGQSF 205 >UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase bacC; n=5; Bacillus|Rep: Bacilysin biosynthesis oxidoreductase bacC - Bacillus subtilis Length = 253 Score = 83.4 bits (197), Expect = 4e-15 Identities = 60/194 (30%), Positives = 101/194 (52%), Gaps = 6/194 (3%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 DK V ITG A+GIG + V+ L + ++ + DI E G+++ + N+ ++ F ++D Sbjct: 5 DKTVLITGGASGIGYAAVQAFLGQQA-NVVVADIDEAQGEAMVRKENN---DRLHFVQTD 60 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTL 346 +T+E + + V GG+DV+INNA + + + K ++VN+T + + Sbjct: 61 ITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSK 120 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 A++ M + GK G +IN SV L +P Y A+K VLQ + + ++K + Sbjct: 121 HALKHM--LAAGK-GNIINTCSVGGLVAWPDIPAYNASKGGVLQLTKSMA--VDYAKHQI 175 Query: 527 RVLTVCFGATDTAL 568 RV VC G DT L Sbjct: 176 RVNCVCPGIIDTPL 189 >UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyces avermitilis|Rep: Putative dehydrogenase - Streptomyces avermitilis Length = 258 Score = 83.0 bits (196), Expect = 5e-15 Identities = 60/199 (30%), Positives = 104/199 (52%), Gaps = 6/199 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 +VV I+GAA G GE R+ ++EG K + + D+ ++ G++L E+ ++Y DV Sbjct: 7 RVVLISGAARGQGEQEARLFVEEGAK-VVVADVLDDQGEALAKEIGARY------VHLDV 59 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGI----YKKAIEVNVTALITSTLK 349 E+ + + G ID ++NNA ++ ND +G +++ ++VN + +K Sbjct: 60 GREDDWQAAVTVAKDAYGHIDGLVNNAGILRFNDLVGTPLAEFQQIVQVNQVGVFLG-IK 118 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 + + +G GGT++N +S A LT + Y ATK A++ + V E +K +R Sbjct: 119 TVAPEIEAAG--GGTIVNTASYAGLTGMAYVGAYTATKHAIVGLTR-VAALELAAKK-IR 174 Query: 530 VLTVCFGATDTALLTDEKL 586 V VC GA DTA+ +L Sbjct: 175 VNAVCPGAIDTAMSNPSQL 193 >UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR; n=6; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1 Length = 260 Score = 83.0 bits (196), Expect = 5e-15 Identities = 59/206 (28%), Positives = 101/206 (49%), Gaps = 7/206 (3%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 +K + ITG A+GIG + ++L G K I I D+AE+ G +L + + + F + D Sbjct: 14 NKRILITGGASGIGAASAKLLASRGAK-IIIADLAEDLGHALAQQAWAS-DHTINFMKVD 71 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-------KAIEVNVTALITST 343 VT + V++ GG+DVVINNA + + +++ + + VNV + Sbjct: 72 VTQAAEVNALFAYAVEQLGGLDVVINNAGVDHPPAPLHQLTEDDFDRCMTVNVKGVWHCM 131 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 AI + H GG VINV+S+A L + ++ Y A+K AV+ + +++ Sbjct: 132 RAAIACLSPHGGGH---VINVASIAGLRSAPMLSAYSASKHAVIGLTKSAA--IEYARAN 186 Query: 524 VRVLTVCFGATDTALLTDEKLGTFDK 601 +R VC DT ++ + L +K Sbjct: 187 IRFNAVCPSFIDTPMVRNSMLNMNEK 212 >UniRef50_P00334 Cluster: Alcohol dehydrogenase; n=485; Drosophilidae|Rep: Alcohol dehydrogenase - Drosophila melanogaster (Fruit fly) Length = 256 Score = 83.0 bits (196), Expect = 5e-15 Identities = 57/189 (30%), Positives = 93/189 (49%), Gaps = 2/189 (1%) Frame = +2 Query: 11 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVE-LNSKYGNKTKFYRSDV 187 V+F+ G GIG + LL +K++ ILD E +++ +N K FY DV Sbjct: 10 VIFVAGLG-GIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKV--TVTFYPYDV 66 Query: 188 TNE-EHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 364 T +L + + +DV+IN A +++D ++ I VN T L+ +T ++ Sbjct: 67 TVPIAETTKLLKTIFAQLKTVDVLINGAGILDDHQ--IERTIAVNYTGLVNTTTAILDFW 124 Query: 365 GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVC 544 K GG GG + N+ SV + +P+Y TK+AV+ F++ + + TGV TV Sbjct: 125 DKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPI--TGVTAYTVN 182 Query: 545 FGATDTALL 571 G T T L+ Sbjct: 183 PGITRTTLV 191 >UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=1; Bacillus halodurans|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Bacillus halodurans Length = 247 Score = 82.6 bits (195), Expect = 7e-15 Identities = 57/222 (25%), Positives = 106/222 (47%), Gaps = 10/222 (4%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 +DKV +TGA GIG+ +V+ +++G I EA + ++ LN G K Y S Sbjct: 4 RDKVAIVTGATRGIGKEIVKTFVEQGAFVYGIYASNHEAAREIEKTLNQ--GEKCVSYVS 61 Query: 182 DVTNEEHFL-GILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 340 +++ F+ + +VV + +D+++NNA + D +++ ++VN T Sbjct: 62 GSVDDQLFIHSLFKSVVDKHNRLDILVNNAGITRDQFLFQMDDQSWQQVLQVNFGGTYTC 121 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 A+ M + GK ++NV SV + Y A+K A++ + + R +S+ Sbjct: 122 CHAALPYMERKKQGK---IVNVVSVTGVVGREAQTNYGASKGAIIGLTRLLAR--KYSEK 176 Query: 521 GVRVLTVCFGATDTALL---TDEKLGTFDKYLEFFMLGPTKE 637 G+ + + G +T ++ +EKL F ++ LG TKE Sbjct: 177 GISINAIAPGMIETEMIKQVPEEKLKNFLRFTNAKKLGSTKE 218 >UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Leptospira interrogans Length = 256 Score = 82.6 bits (195), Expect = 7e-15 Identities = 60/199 (30%), Positives = 100/199 (50%), Gaps = 7/199 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 KDKV +TG +TGIG++VV+ + +GVK + E GK L+ E+ ++ G F Sbjct: 6 KDKVAIVTGGSTGIGKAVVKEFVSKGVK-VVFCGRRLEEGKKLESEIRAE-GGDVYFVVC 63 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALM--NDSI-----GIYKKAIEVNVTALITS 340 DVT+ E +++A +++ G +D INNA +M N + ++ K + VN+ S Sbjct: 64 DVTSGEQVKKVVDAALEKFGRLDFGINNAGIMGLNHLLHEYPEDVWDKVVNVNLKGTWLS 123 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 I M K GG V+NVSS++ + + Y A K V+ + ++K Sbjct: 124 MKYQIPEMIKMG---GGVVVNVSSISGINGVVGINPYAAAKHGVVGLTKSAAL--EYAKK 178 Query: 521 GVRVLTVCFGATDTALLTD 577 +R+ +C GA T +L + Sbjct: 179 NIRINAICPGAVKTEILDE 197 >UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3; Bacillus|Rep: Cyclohexanol dehydrogenase - Bacillus sp. SG-1 Length = 279 Score = 82.2 bits (194), Expect = 1e-14 Identities = 54/197 (27%), Positives = 98/197 (49%), Gaps = 7/197 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 ++K ITGA +G+G+S L EG+ IA++DI EE G VE+ + G F ++ Sbjct: 31 ENKAAIITGAGSGLGQSAAVRLAKEGI-DIAVVDINEEGGNE-TVEMVKQKGVNAIFIKA 88 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNVTALITS 340 DV+ E ++ V+E G +D NNA + +N I ++ + +N+ + Sbjct: 89 DVSKAEEVKNYVDKTVEEFGKVDYFFNNAGISGSGQYFLNTEIEEIEQVVSINLMGALYG 148 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 E+M K+ GG+++N +S A + + Y ATK ++ + + ++K Sbjct: 149 VRYVAEVMMKNG---GGSIVNTASSAGVIGQDSVVTYSATKHGIIGLTKSM--VAEYAKE 203 Query: 521 GVRVLTVCFGATDTALL 571 G+RV + G T+T ++ Sbjct: 204 GLRVNAIAPGPTETPMV 220 >UniRef50_Q6XPZ7 Cluster: Short-chain dehydrogenase/reductase; n=1; Apis mellifera|Rep: Short-chain dehydrogenase/reductase - Apis mellifera (Honeybee) Length = 246 Score = 82.2 bits (194), Expect = 1e-14 Identities = 52/188 (27%), Positives = 100/188 (53%), Gaps = 9/188 (4%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 D+V +TGA +GIG+ ++ L+ +G+K I I ++ K+L EL SK G K + D Sbjct: 7 DEVALVTGANSGIGKCLIECLVGKGMKVIGIAPQVDKM-KTLVEELKSKPG-KLVPLQCD 64 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITSTL 346 ++N+ L ++ V + G ID++INNA L ND + +KK ++N+ L Sbjct: 65 LSNQNDILKVIEWVEKNLGAIDILINNATINIDVTLQNDEVLDWKKIFDINLLGLTCMIQ 124 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALT---QSHVMPIYFATKSAVLQFSNCVGRPEHFSK 517 + +++M K G G ++N++ + L + P Y A+K A+ ++C+ + Sbjct: 125 EVLKLM-KKKGINNGIIVNINDASGLNLLPMNRNRPAYLASKCALTTLTDCLRSELAQCE 183 Query: 518 TGVRVLTV 541 + ++V+++ Sbjct: 184 SNIKVISI 191 >UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacteria|Rep: Cyclopentanol dehydrogenase - Comamonas sp. (strain NCIMB 9872) Length = 250 Score = 81.4 bits (192), Expect = 2e-14 Identities = 53/166 (31%), Positives = 84/166 (50%), Gaps = 6/166 (3%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 DKVV +TG A G+G + +L EG + + D+ EE G E+ + G K F D Sbjct: 6 DKVVLVTGGAMGMGLTHCTLLAREGAT-VYLSDMNEELGHQAVAEIR-RQGGKAHFLHLD 63 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 346 VTNE H+ G ++ ++ E +D ++NNA ++ + S + + E+NV ++ T Sbjct: 64 VTNENHWTGAVDTILAESDRLDALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTR 123 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 484 IE M K G ++NVSS+ L + Y A+K AV F+ Sbjct: 124 AVIEPMRK---AHKGCIVNVSSIYGLVGAPGAAAYEASKGAVRLFT 166 >UniRef50_Q89KQ8 Cluster: Blr4846 protein; n=2; Proteobacteria|Rep: Blr4846 protein - Bradyrhizobium japonicum Length = 255 Score = 81.0 bits (191), Expect = 2e-14 Identities = 54/170 (31%), Positives = 87/170 (51%), Gaps = 5/170 (2%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 D+VV ITG A+GIG + VR +G + +A LDI E AG SL E+ + G F R D Sbjct: 11 DRVVLITGGASGIGAAFVRAFAAQGAR-VAFLDIDEAAGGSLVEEVAAASGAAPLFVRCD 69 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI--- 355 + + + + V G V++NNAA ND + + +I LK + Sbjct: 70 LLDIDALRAAIAQVRGSLGDAAVLVNNAA--NDQRQVLAEVTPSEFDWMIGVNLKHVFFA 127 Query: 356 --EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGR 499 ++ + GG++IN+SS+A + +P+Y A K+A++ F+N + R Sbjct: 128 AQAVVPQMQARGGGSIINMSSIAWMRGGPALPVYAAAKAAIVGFTNSLAR 177 >UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=1; Hyphomonas neptunium ATCC 15444|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Hyphomonas neptunium (strain ATCC 15444) Length = 262 Score = 80.6 bits (190), Expect = 3e-14 Identities = 53/191 (27%), Positives = 93/191 (48%), Gaps = 2/191 (1%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 ++KV ITGAA+GIG + R+L EG H+ + D+ + GKS+ +L G + Sbjct: 7 ENKVAVITGAASGIGAATARLLAREGA-HVVLADVNDNGGKSIAADL----GPTAMAVKC 61 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSIGIYKKAIEVNVTALITSTLKAI 355 DV++ ++ A V+ G ID++ NNA + S+ I E + + S A Sbjct: 62 DVSSAAEVEALVKAAVERHGRIDILFNNAGIGSFGTSVEIQPAEWERVIAIDLHSVYYAC 121 Query: 356 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535 H +G ++N +S++ L + Y A K AV+ ++ + +H + G+RV Sbjct: 122 HFAIPHM-PRGSAIVNTASISGLGGDYRFAAYNAAKGAVVNYTRALA-VDH-GRDGIRVN 178 Query: 536 TVCFGATDTAL 568 +C G +T + Sbjct: 179 ALCPGLVETPI 189 >UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Leeuwenhoekiella blandensis MED217 Length = 257 Score = 80.6 bits (190), Expect = 3e-14 Identities = 52/180 (28%), Positives = 92/180 (51%), Gaps = 6/180 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K+KV +TG A+G+G+S ++L EG K I + DI EE GK + V+ + G + F + Sbjct: 5 KNKVAIVTGGASGLGKSSAKLLAREGAK-IVVSDIDEEGGKKV-VQQIKEDGGEAIFIKQ 62 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAAL-----MND-SIGIYKKAIEVNVTALITST 343 DV E+ + ++ ++ G + ++ N+A + + D ++ +K I++N+ T Sbjct: 63 DVAKEDEWKNVIETTLETYGKLHILANSAGIGLGGTVEDVTLEDWKNLIDINLNGTFLGT 122 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 I+ G +GG++IN SS+ L +P Y A+K V F+ H +K G Sbjct: 123 KYGIK--GMRKTDEGGSIINFSSIEGLIGDPNLPAYNASKGGVTIFTKSAAL--HCAKQG 178 >UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caulobacter sp. K31|Rep: Short-chain dehydrogenase/reductase SDR - Caulobacter sp. K31 Length = 277 Score = 80.2 bits (189), Expect = 4e-14 Identities = 55/193 (28%), Positives = 100/193 (51%), Gaps = 6/193 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K+ +TGAA G+G ++ + L+EG + + D++EE EL + + R DV Sbjct: 9 KIAIVTGAARGLGAAIAKRYLEEGAT-VVLADLSEEKTTERAAELGAGAHGR----RCDV 63 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 349 + E F +++A V E G +D+++NNA + S+ + + VNV+++ Sbjct: 64 GDWEAFSTLIDATVAEFGRLDILVNNAGINRAGLVPGFSLQHWDDLLRVNVSSVFYGCRA 123 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 AI M + GG +INV+S+A L + Y A+K+AV+ F+ + +H + +R Sbjct: 124 AIPHMRRQGGG---AIINVASIAGLRGETLAAAYSASKAAVVNFTRSLAL-DH-ADENIR 178 Query: 530 VLTVCFGATDTAL 568 V +C G+ +T + Sbjct: 179 VNAICPGSVETEM 191 >UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325; n=2; Thermotoga|Rep: Uncharacterized oxidoreductase TM_0325 - Thermotoga maritima Length = 251 Score = 80.2 bits (189), Expect = 4e-14 Identities = 62/191 (32%), Positives = 93/191 (48%), Gaps = 6/191 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KVV ITGA +GIG+ + + G K +AI DI+EE GK VEL G + F DV Sbjct: 6 KVVLITGAGSGIGKKAAVMFAERGAK-VAINDISEEKGKE-TVELIKSMGGEAAFIFGDV 63 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTLK 349 + I+ V+ G +D+++NNA ++ S + K + VNV + Sbjct: 64 AKDAE--QIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFLLSKY 121 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 A+E M K GG ++NVSS A L +Y +K+A+L + + + G+R Sbjct: 122 AVEQMKKQG---GGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLA--VDYVDYGIR 176 Query: 530 VLTVCFGATDT 562 V VC G T + Sbjct: 177 VNAVCPGTTQS 187 >UniRef50_Q8YQR6 Cluster: All3753 protein; n=6; Bacteria|Rep: All3753 protein - Anabaena sp. (strain PCC 7120) Length = 263 Score = 79.8 bits (188), Expect = 5e-14 Identities = 60/192 (31%), Positives = 94/192 (48%), Gaps = 6/192 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 + ITGAA+GIG +V I + ++ ++D A+E + + +E K+G K D+ Sbjct: 7 QTALITGAASGIGYELVCIFAENDY-NLVLVDRAKEKLEEIAIEFQDKFGISVKPIVRDL 65 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA-----LMNDS-IGIYKKAIEVNVTALITSTLK 349 + I V Q +DV++NNA L ND+ + + ++VNV T Sbjct: 66 SKTTSPEEIFQEVEQANIKVDVLVNNAGFGTYGLFNDTNLTDELEMLQVNVVCTTHLTKL 125 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 ++ M + GK ++NVSS AA +M +YFATK+ VL FS + TGV Sbjct: 126 FLKNMVQQGEGK---ILNVSSAAAFQPGPLMAVYFATKAYVLSFSEALA--NELDGTGVT 180 Query: 530 VLTVCFGATDTA 565 V +C G T +A Sbjct: 181 VTVLCPGTTQSA 192 >UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Bacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Pseudomonas putida (strain KT2440) Length = 262 Score = 79.8 bits (188), Expect = 5e-14 Identities = 54/197 (27%), Positives = 93/197 (47%), Gaps = 7/197 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KVV +TGA +GIG + G +A+ DI+ + G VEL G + F+ DV Sbjct: 10 KVVLVTGAGSGIGRATALAFAQSGAS-VAVADISTDHGLKT-VELVKAEGGEATFFHVDV 67 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 346 +E +L VV GG+D+ NNA + + + + +++ I+VN++++ Sbjct: 68 GSEPSVQSMLAGVVAHYGGLDIAHNNAGIEANIVPLAELDSDNWRRVIDVNLSSVFYCLK 127 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 I +M K GG ++N +S + L + + Y ATK V+ + ++ + Sbjct: 128 GEIPLMLKRG---GGAIVNTASASGLIGGYRLSGYTATKHGVVGLTKAAA--IDYANQNI 182 Query: 527 RVLTVCFGATDTALLTD 577 R+ VC G D+ L D Sbjct: 183 RINAVCPGPVDSPFLAD 199 >UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 258 Score = 79.8 bits (188), Expect = 5e-14 Identities = 54/190 (28%), Positives = 97/190 (51%), Gaps = 3/190 (1%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TG A G+G + R+ + EG + I D+ + G++L EL G+ +F R DV Sbjct: 7 KVAIVTGGARGMGAATCRLFVAEGAC-VVIGDVLDAEGEALAREL----GDAARFMRLDV 61 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGIYKKAIEVNVTALITSTLKAIEI 361 +E +++ + +A +++ G IDV++NNAA++ + K+ E V+ + T I Sbjct: 62 ADEANWVRVTDATMEQFGRIDVLVNNAAVLTFGGITELSKRDFERAVSINLVGTFVGIRT 121 Query: 362 MGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538 + H K G+++N+SSV L + + Y ++K V + GVRV + Sbjct: 122 IAPHMIAQKSGSIVNISSVDGLRGVNALAAYVSSKWGVRGLTKVAAL--ELGHQGVRVNS 179 Query: 539 VCFGATDTAL 568 + G +TA+ Sbjct: 180 IHPGGVNTAM 189 >UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1; Psychroflexus torquis ATCC 700755|Rep: 3-oxoacyl-[ACP] reductase - Psychroflexus torquis ATCC 700755 Length = 251 Score = 79.8 bits (188), Expect = 5e-14 Identities = 61/188 (32%), Positives = 101/188 (53%), Gaps = 2/188 (1%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K K ITG + GIG+S+ L +EGV +IAI +EA + + EL K G K Sbjct: 6 KGKNAIITGGSKGIGKSIALHLAEEGV-NIAICARGKEALQKTKNELLEK-GVKVFTQTC 63 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITSTLKAI 355 DV + E F L AV E G +D+++NNA+ M D ++ ++++++ A + +T K + Sbjct: 64 DVGDSEQFNLFLTAVKNEFGSVDILVNNASALTMGDEYQDWEASLQIDLMASVRATKKVV 123 Query: 356 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535 M + SG G ++ +SSV+ L +S P Y A K+A++ +S + + +RV Sbjct: 124 PWMSE-SG--SGNILFISSVSGL-ESGSPPAYAAAKAALISYSKTMA--VQLAPQHIRVN 177 Query: 536 TVCFGATD 559 T+ GA + Sbjct: 178 TIAPGAIE 185 >UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=9; Firmicutes|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Oceanobacillus iheyensis Length = 253 Score = 79.4 bits (187), Expect = 7e-14 Identities = 51/201 (25%), Positives = 102/201 (50%), Gaps = 7/201 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 KDKV +TGAA+G+G+++ + EG K + + D+ EE +S+ E+ S G T + Sbjct: 4 KDKVAIVTGAASGMGKAIATLYASEGAK-VIVADLNEEGAQSVVEEITSNNGVATAI-KV 61 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMN--DSIG-----IYKKAIEVNVTALITS 340 ++ +E +++ V G +D+++NNA +M+ +++G + ++N ++ + Sbjct: 62 NIAQKEDIDKMIDTAVDTYGTLDILVNNAGIMDGFEAVGDVEDDRWDLIFDINTKGVMRA 121 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 KAI I + + G ++N +S L +H Y A+K AV+ + G ++ + Sbjct: 122 MRKAIPIFLEK---ESGVIVNTASTGGLNGAHAGAAYGASKHAVIGLTKNTG--YMYANS 176 Query: 521 GVRVLTVCFGATDTALLTDEK 583 G+R + G T + + K Sbjct: 177 GIRCNAIAPGGVATNITSSLK 197 >UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419; n=15; Staphylococcus|Rep: Uncharacterized oxidoreductase SSP0419 - Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 /DSM 20229) Length = 234 Score = 79.4 bits (187), Expect = 7e-14 Identities = 58/207 (28%), Positives = 105/207 (50%), Gaps = 7/207 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAI-LDIAEEAGKSLQVELNSKYGNKTKFYR 178 +DKV +TGA++GIG S+ L ++GVK + D + A + +++ N + +T Sbjct: 5 QDKVAVVTGASSGIGASIAETLANQGVKVVLTGRDESRLAEVAKRIQDNKQAVVETSIV- 63 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITS 340 DVT++E ++ ++ G ID+++N+A LM S + ++ I+VN+ + + Sbjct: 64 -DVTHKEEVTELVEKTKEKFGQIDILVNSAGLMLSSAITEGDVEAWEAMIDVNIKGTLYT 122 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 + M S G +IN++S++ + +Y A+K+AV + G + +KT Sbjct: 123 INAVLPSMLNQSSGH---IINIASISGFEVTKKSTLYSASKAAVHSITQ--GLEKELAKT 177 Query: 521 GVRVLTVCFGATDTALLTDEKLGTFDK 601 GVRV ++ G DT L D G K Sbjct: 178 GVRVTSISPGMVDTPLSGDTDWGARKK 204 >UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus iheyensis|Rep: Oxidoreductase - Oceanobacillus iheyensis Length = 257 Score = 79.0 bits (186), Expect = 9e-14 Identities = 61/197 (30%), Positives = 103/197 (52%), Gaps = 7/197 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 +DKV+ +TGAA GIG+ VVR + + K + ++D+ E+A KS+Q EL N + ++ Sbjct: 5 QDKVIIVTGAAGGIGKEVVRKVANAQAK-VVLVDLNEDAIKSVQAELGLTEEN-SFVVKA 62 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 340 DV+NEE+ ++ + + G ID +NNA + + I + +NV ++ Sbjct: 63 DVSNEENVKNYVDQTIAKFGRIDGFVNNAGVEGPAKSIEEITEKEFDFVYGINVKGVLFG 122 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 + +M K G+++N +SVA L S M +Y ++K AV+ N V E + Sbjct: 123 LKYVLPVM---KAQKSGSIVNTASVAGLIGSPSMALYNSSKHAVMGL-NKVAALES-AAF 177 Query: 521 GVRVLTVCFGATDTALL 571 VRV TV G +T ++ Sbjct: 178 NVRVNTVNPGVINTQMM 194 >UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Parvibaculum lavamentivorans DS-1 Length = 268 Score = 79.0 bits (186), Expect = 9e-14 Identities = 55/197 (27%), Positives = 95/197 (48%), Gaps = 9/197 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TGAA GIG + + L EG K + D E G+ + E+ + G T F+R DV Sbjct: 7 KVAIVTGAAKGIGAATAKALAREGAK-VVCSDFDAENGQVVADEIAGEGGTAT-FFRHDV 64 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITSTL 346 T+E + ++ ++ GG+ VV+NNA + + ++ ++ IEV++ ++ Sbjct: 65 TDEAQWEAVVKLAEEKFGGLHVVVNNAGIAPEAGPIEEKTLADWRHTIEVDLDSVFLGCK 124 Query: 347 KAIEIMGKHS--GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 I + K++ GG GG ++N+SS+ L Y A K V + + Sbjct: 125 HGIRTIKKYTSKGGAGGAIVNISSILGLVGQSGASDYNAAKGGVRLLTKSAALECADAGY 184 Query: 521 GVRVLTVCFGATDTALL 571 +RV +V G DT ++ Sbjct: 185 NIRVNSVHPGYIDTPMV 201 >UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Methylobacterium sp. 4-46 Length = 255 Score = 79.0 bits (186), Expect = 9e-14 Identities = 60/203 (29%), Positives = 96/203 (47%), Gaps = 6/203 (2%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TG A GIG + R +EG + + DI EAG + N + +F DV Sbjct: 7 KVALVTGGARGIGLATARRFAEEGAAAVILADIDAEAG-ARAAATNPVF----RFAPLDV 61 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAAL----MNDSIGI--YKKAIEVNVTALITSTLK 349 T + + + V +GG+DVV+N A + +S+ + +++ VNV Sbjct: 62 TQDAAWQDATDEAVAREGGLDVVVNCAGIAVVATIESVTLEQWRRVQAVNVDGTFLGCRH 121 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 A+ +M K G+GG +IN+SSV+ + H + Y A+K AV + V G+R Sbjct: 122 AVRVM-KPPAGRGGAIINLSSVSGIIGGHNLAAYNASKGAVRLLTKSVALHCARQGYGIR 180 Query: 530 VLTVCFGATDTALLTDEKLGTFD 598 ++ G T+T +L D G D Sbjct: 181 CNSIHPGFTETDMLHDLAAGGRD 203 >UniRef50_Q6UWP2 Cluster: Dehydrogenase/reductase SDR family member 11 precursor; n=30; Euteleostomi|Rep: Dehydrogenase/reductase SDR family member 11 precursor - Homo sapiens (Human) Length = 260 Score = 79.0 bits (186), Expect = 9e-14 Identities = 59/198 (29%), Positives = 98/198 (49%), Gaps = 11/198 (5%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--KSLQVELNSK-YGNKTKF 172 +D++ +TGA+ GIG +V R L+ +G+K ++ A G + L E S Y Sbjct: 10 RDRLALVTGASGGIGAAVARALVQQGLK---VVGCARTVGNIEELAAECKSAGYPGTLIP 66 Query: 173 YRSDVTNEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALI 334 YR D++NEE L + +A+ + G+D+ INNA L++ S +K VNV AL Sbjct: 67 YRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALS 126 Query: 335 TSTLKAIEIMGKHSGGKGGTVINVSSVAA--LTQSHVMPIYFATKSAVLQFSNCVGRPEH 508 T +A + M K G +IN++S++ + V Y ATK AV + + + Sbjct: 127 ICTREAYQSM-KERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELR 185 Query: 509 FSKTGVRVLTVCFGATDT 562 ++T +R + G +T Sbjct: 186 EAQTHIRATCISPGVVET 203 >UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2; Bacteria|Rep: Short-chain dehydrogenase - Symbiobacterium thermophilum Length = 254 Score = 78.6 bits (185), Expect = 1e-13 Identities = 60/194 (30%), Positives = 90/194 (46%), Gaps = 6/194 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV ITGAA G+G + + EG + + I D+ EE G++ Q G F R+DV Sbjct: 7 KVAIITGAAMGMGAATAELFAREGAR-VVIADLNEELGRA-QARKIQDAGGAAAFVRADV 64 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 367 + ++ V G +DV +NNAA D+ + E A+I LK + + Sbjct: 65 SRAGDVEAMVQFAVDTFGRLDVAVNNAAHSPDTRPL-ADLDEAVWDAVIGVDLKGVALCL 123 Query: 368 KHS------GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 K+ G GG++IN+SSV+ + P Y A K V+ + +S G+R Sbjct: 124 KYELRQMLKQGGGGSIINISSVSGIRPQPGTPAYVAAKHGVIGLTKQAAM--DYSPHGIR 181 Query: 530 VLTVCFGATDTALL 571 V V GA DT +L Sbjct: 182 VNAVAPGAVDTPML 195 >UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductase; n=3; Lactobacillales|Rep: 3-oxoacyl-acyl carrier protein reductase - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 249 Score = 78.6 bits (185), Expect = 1e-13 Identities = 57/200 (28%), Positives = 100/200 (50%), Gaps = 8/200 (4%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK-FYR 178 KDKV ITG GIG + + EG K + + + G++ +K+G+ F + Sbjct: 6 KDKVAIITGGVAGIGLGIAECYVREGAKVVVTANHNVDGGRAAV----AKFGDDVSLFVQ 61 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSI-----GIYKKAIEVNVTALIT 337 DV+ E + +++A + + G +D+++NNA + +N +I ++K I+VN+TA Sbjct: 62 QDVSKEADWQKVIDATIAKFGRVDILVNNAGIGGVNTAIEDLDLADWQKVIDVNLTANFL 121 Query: 338 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSK 517 AI+ M K + G++INVSSVA L + P Y A+K ++ Sbjct: 122 GEKAAIKAM-KQTADAKGSIINVSSVAGLVGLPMAPAYSASKGGSRLLTHATALNLAQRG 180 Query: 518 TGVRVLTVCFGATDTALLTD 577 +RV +V G DT+++ + Sbjct: 181 IDIRVNSVHPGWIDTSIVPE 200 >UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=3; Clostridium|Rep: 7-alpha-hydroxysteroid dehydrogenase - Eubacterium sp. (strain VPI 12708) Length = 266 Score = 78.6 bits (185), Expect = 1e-13 Identities = 52/211 (24%), Positives = 105/211 (49%), Gaps = 10/211 (4%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGKSLQVELNSKYGNKTKFYR 178 KDKV+ +T + GIG ++ + EG K ++ ++ E K+ E+N+ GN K+ Sbjct: 4 KDKVILVTASTRGIGLAIAQACAKEGAKVYMGARNL--ERAKARADEMNAAGGN-VKYVY 60 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINN---------AALMNDSIGIYKKAIEVNVTAL 331 +D T EE ++ ++ +++++G IDV++NN + N ++ K + +N+ ++ Sbjct: 61 NDATKEETYVTMIEEIIEQEGRIDVLVNNFGSSNPKKDLGIANTDPEVFIKTVNINLKSV 120 Query: 332 ITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHF 511 ++ A++ M ++ GG++IN+SSV L Y +K+A+ + + H Sbjct: 121 FIASQTAVKYMAENG---GGSIINISSVGGLIPDISQIAYGTSKAAINYLTKLIA--VHE 175 Query: 512 SKTGVRVLTVCFGATDTALLTDEKLGTFDKY 604 ++ +R V G T T + D F + Sbjct: 176 ARHNIRCNAVLPGMTATDAVQDNLTDDFRNF 206 >UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR - Solibacter usitatus (strain Ellin6076) Length = 275 Score = 78.6 bits (185), Expect = 1e-13 Identities = 59/193 (30%), Positives = 95/193 (49%), Gaps = 6/193 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV F+TG +G+G ++ L G IA+ DI EA + + + G K+ + DV Sbjct: 7 KVAFVTGGGSGLGRALSEELARRGAV-IAVTDINAEAAEHVAAAITES-GGKSCSMKLDV 64 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMN----DSIGI--YKKAIEVNVTALITSTLK 349 + E +++VV G +D + NNA ++ +G+ + + I+VN+ ++ T Sbjct: 65 SQPEDVAASIDSVVGRYGRLDYMFNNAGIIILGEVRDMGLEHWHRLIDVNLLGVLYGTTA 124 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 A M + G ++N++SV L Y ATK AV+ S + RPE SK GVR Sbjct: 125 AYSHMVRQGYGH---IVNIASVGGLVPLPTYAAYAATKHAVVGLSTSM-RPE-ASKLGVR 179 Query: 530 VLTVCFGATDTAL 568 + VC G +T L Sbjct: 180 ITVVCPGTMNTGL 192 >UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus sp. B14905 Length = 254 Score = 78.6 bits (185), Expect = 1e-13 Identities = 55/195 (28%), Positives = 95/195 (48%), Gaps = 6/195 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 ++KV ITG TGIG+ + EG K I I DI E++G ++ + +G + F Sbjct: 7 ENKVAVITGGGTGIGKETALLFAKEGAK-IVITDINEQSGNETVSDIQA-FGGEALFVLH 64 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 343 DV+NE+ + + + + +D++ NNA L + + + + +NVT + Sbjct: 65 DVSNEDDWKKVADEAIHTFNKVDILFNNAGIYIIKPLAEIELSDWNRLMSINVTGVFLGM 124 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 + +M K + G+VIN SS+A LT + +Y A+K AV + ++ G Sbjct: 125 KHIMPLMAKQN---KGSVINASSIAGLTGAAGHVLYGASKGAVRIMTKDAAM--EYAPYG 179 Query: 524 VRVLTVCFGATDTAL 568 VRV ++ G DT + Sbjct: 180 VRVNSIHPGYIDTGM 194 >UniRef50_A1IFS9 Cluster: Short chain dehydrogenase family protein; n=1; Candidatus Desulfococcus oleovorans Hxd3|Rep: Short chain dehydrogenase family protein - Candidatus Desulfococcus oleovorans Hxd3 Length = 273 Score = 78.6 bits (185), Expect = 1e-13 Identities = 60/194 (30%), Positives = 96/194 (49%), Gaps = 6/194 (3%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 DKV +TG A+G+G +V +L G + I DI E+ + + + + G T + D Sbjct: 6 DKVFIVTGGASGMGRAVCELLGTRGA-ILIIADIDGESAEKVAAGITAAGGRATGVF-LD 63 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 346 T +E +++ E G +D + NNA ++ + S + + ++VN ++T TL Sbjct: 64 TTADETVRRLVDETAAEYGRLDYMFNNAGILIAGEVRDMSDDHWARILDVNFRGVLTGTL 123 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 A IM + G +IN +S A L V+ Y TK AV+ S + RPE +K GV Sbjct: 124 AAYRIMVEQGFGH---IINTASTAGLVPIPVITAYATTKHAVVGLSISL-RPE-AAKAGV 178 Query: 527 RVLTVCFGATDTAL 568 RV VC G T++ Sbjct: 179 RVSVVCPGYVSTSI 192 >UniRef50_Q28GY1 Cluster: Novel protein containing short chain dehydrogenase domain; n=4; Deuterostomia|Rep: Novel protein containing short chain dehydrogenase domain - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 255 Score = 78.2 bits (184), Expect = 2e-13 Identities = 59/196 (30%), Positives = 95/196 (48%), Gaps = 9/196 (4%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-YR 178 K +V +TGA+ GIG +V R+L+ G+K + ++ K L E S T F Y+ Sbjct: 5 KGRVALVTGASVGIGAAVARVLVQHGMKVVGCARSVDKIEK-LAAECQSAGYPGTLFPYK 63 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITS 340 D++NEE L + +A+ G+DV INNA L++ ++ I+VNV AL Sbjct: 64 CDLSNEEEILSMFSAIKTLHQGVDVCINNAGLARPEPLLSGKTEGWRTMIDVNVLALSIC 123 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYF--ATKSAVLQFSNCVGRPEHFS 514 T +A + M K G +IN++SV +F ATK V + + + Sbjct: 124 TREAYQSM-KERNIDDGHIININSVLGHIYQCAKQAHFYCATKHTVTALTEAIRQELREL 182 Query: 515 KTGVRVLTVCFGATDT 562 K+ +RV ++ G +T Sbjct: 183 KSHIRVTSISPGLVET 198 >UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Lin2278 protein - Listeria innocua Length = 253 Score = 78.2 bits (184), Expect = 2e-13 Identities = 51/197 (25%), Positives = 99/197 (50%), Gaps = 8/197 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TGAA+G+G+ + + EG K + + D+ EA + + + G ++V Sbjct: 7 KVAVVTGAASGMGQQIAVLFAKEGAK-VVVADLNLEAAQKTVALIEDEQGTALAVV-ANV 64 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITSTL 346 T ++ ++N + G +D+++NNA +M++ + ++ K +N T ++ +T Sbjct: 65 TKQDDIESMINKATETYGTLDILVNNAGIMDNFVPAGELTDELWDKVFAINTTGVMRATR 124 Query: 347 KAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 KA+ I + KG G ++N++S L S Y A+K AV+ F+ VG ++ Sbjct: 125 KALHIFEE----KGQGVIVNIASAGGLFGSRAGAAYTASKHAVVGFTKNVG--FQYANKN 178 Query: 524 VRVLTVCFGATDTALLT 574 +R + GA +T + T Sbjct: 179 IRCNAIAPGAVNTNIGT 195 >UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain KSM-K16) Length = 247 Score = 78.2 bits (184), Expect = 2e-13 Identities = 64/204 (31%), Positives = 101/204 (49%), Gaps = 7/204 (3%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 +KVV ITG A+GIG + V L +G K + I D +E G++ EL G + F ++D Sbjct: 6 NKVVIITGGASGIGRAAVDAFLAKGAK-VVIADFNKETGEAAVKELTDA-GKQVLFVQTD 63 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAAL--MNDS----IGIYKKAIEVNVTALITSTL 346 V+NE ++ V+ +D++INNA M+ S Y+K ++V + + Sbjct: 64 VSNEPSVQNMVAETVKAYERVDILINNAGFGTMSPSHERTYEDYEKIVKVCQDGVFLGSK 123 Query: 347 KAIEIMGKHSGGKGGTVINVSSV-AALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 AI+ M K GG +IN SS+ ++ Q +P Y A K AV + + ++ Sbjct: 124 HAIKEMIKTG---GGCIINTSSILGSVAQPEALP-YNAAKGAVNTMTKSLA--VEYADKQ 177 Query: 524 VRVLTVCFGATDTALLTDEKLGTF 595 +RV V G +TA + E LG F Sbjct: 178 IRVNAVAPGFVETAAVNKEALGDF 201 >UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=1; Ralstonia eutropha JMP134|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 258 Score = 78.2 bits (184), Expect = 2e-13 Identities = 61/202 (30%), Positives = 100/202 (49%), Gaps = 8/202 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K+ +TG A+G+G + R L EG + + DI AG + + EL G F R DV Sbjct: 6 KIALVTGGASGMGLAFTRRLAQEGAR-VYFTDINGAAGHATESELQGA-GLAVVFLRHDV 63 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGI-----YKKAIEVNVTALITSTLK 349 T E +L +L + G +DV++NNA + ++ +I + + + VN+ ++ Sbjct: 64 TQENDWLRVLEHIGAVDGRLDVLVNNAGIAISHNIETCTTEDFDRTLNVNLKSVFLGCKH 123 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG-- 523 + +M + KGG++INVSS+ A+ V Y A+K+ V S V H ++ G Sbjct: 124 GLALMKQ----KGGSIINVSSITAICGEPVALAYSASKAGVRFLSKSVAL--HCAEKGYA 177 Query: 524 VRVLTVCFGATDTALLTDEKLG 589 +RV ++ G DT LL G Sbjct: 178 IRVNSLHPGYIDTPLLAGSNAG 199 >UniRef50_Q399N8 Cluster: Short-chain dehydrogenase/reductase SDR; n=27; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 595 Score = 78.2 bits (184), Expect = 2e-13 Identities = 59/195 (30%), Positives = 93/195 (47%), Gaps = 7/195 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAI-LDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 KV +TGA +GIG EG +A +D+A +L + L G + R D Sbjct: 328 KVAVVTGAGSGIGRCAALAFAREGATIVACDIDLASAERTALLIGLT---GAQAHAKRVD 384 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTL 346 V + + + V GG DVVINNA + ++ S +++ + VN+ +I + Sbjct: 385 VGSADEMEALATWVGSALGGADVVINNAGIGMAGGILDTSTRHWERILHVNLWGVIHGSR 444 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 + M G GG ++N +S AA S +P Y TK+AVL S C+ R E ++ G+ Sbjct: 445 LFAQQMAAR--GTGGHIVNTASAAAFGPSRDLPAYATTKAAVLMLSECM-RAE-LAEQGI 500 Query: 527 RVLTVCFGATDTALL 571 V VC G +T ++ Sbjct: 501 GVTAVCPGFAETGIM 515 >UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 252 Score = 78.2 bits (184), Expect = 2e-13 Identities = 60/191 (31%), Positives = 90/191 (47%), Gaps = 6/191 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV ITG ATGIG + + EG + I DI EE G S VE G F R DV Sbjct: 7 KVALITGGATGIGRATALLFAREGA-CVLIGDINEE-GASETVEAVRAAGGDAAFRRCDV 64 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 349 + EE ++ A +E G +DVV NA L+ S ++ + +N+TA T Sbjct: 65 SGEEEIAALVAAAGEEYGRLDVVFGNAGLLRTRPLEDLSTKEFELHLRINLTANFLLTKY 124 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 A +M +H +GG++I ++S L + Y A+K ++ + + + + +R Sbjct: 125 AAPVMRRH---EGGSIIFMASAGGLRGTRGSVAYNASKGGLVNMTRSLA--DELAPHNIR 179 Query: 530 VLTVCFGATDT 562 V VC G DT Sbjct: 180 VNCVCPGWVDT 190 >UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2; Actinomycetales|Rep: Short chain dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 267 Score = 78.2 bits (184), Expect = 2e-13 Identities = 57/190 (30%), Positives = 93/190 (48%), Gaps = 7/190 (3%) Frame = +2 Query: 20 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTNEE 199 +TG A G+G + L D G + I D+ EE G++ + K G T F + DVT++ Sbjct: 13 VTGGAKGLGAGMAAALADAGAA-VVIGDVLEEEGRATADSVG-KTGVDTGFVKLDVTDDG 70 Query: 200 HFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLKAIEI 361 ++ + A V++ GG+D+++NNA + S+ + ++ EVN+ + + Sbjct: 71 NWERAVAATVEQLGGLDLLVNNAGIEISSLVVDIDPADIRRMCEVNILGVALGLKHGLRA 130 Query: 362 MGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538 M + G GG ++NVSSVAA + Y ATKSAV + + + GVRV Sbjct: 131 MRPGGAAGSGGAIVNVSSVAATIPFPGIAGYSATKSAVDRLTRVAAQEAGKLGYGVRVNC 190 Query: 539 VCFGATDTAL 568 V G T + Sbjct: 191 VYPGLVATEM 200 >UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 253 Score = 77.8 bits (183), Expect = 2e-13 Identities = 58/197 (29%), Positives = 97/197 (49%), Gaps = 7/197 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 KDKV +TG A+GIGE+ VR+ +G + I D G+ L EL S+ + Sbjct: 9 KDKVAIVTGGASGIGEATVRLFASQGAS-VVIAD-RSALGEKLAREL-SESSLAAHYSEV 65 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 340 DV+ E+ +++ V G +D+++ NA + + S + +++ I+VN+T + S Sbjct: 66 DVSREDDTRRLIDDTVSRFGRLDIMVANAGIAHPSAPVEDVSVEQWQQMIDVNLTGVFLS 125 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 AI M K G GG ++N++S+ Y A K V+ + +G H ++ Sbjct: 126 NKLAIVQMKKQ--GTGGAIVNMASILGHVGMPGAASYNAAKGGVVNLTRSLG-VSH-AQD 181 Query: 521 GVRVLTVCFGATDTALL 571 G+RV VC G T L+ Sbjct: 182 GIRVNAVCPGFVATPLI 198 >UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Pelobacter|Rep: Short-chain dehydrogenase/reductase SDR - Pelobacter propionicus (strain DSM 2379) Length = 283 Score = 77.8 bits (183), Expect = 2e-13 Identities = 57/206 (27%), Positives = 102/206 (49%), Gaps = 10/206 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV ITGA GIG ++ L +G + + D+ + + E+ ++ G K R+DV Sbjct: 24 KVAIITGAGRGIGRAIALRLGADGAAMV-VSDVNGDNATKVAEEIKAR-GGKAMALRTDV 81 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVT-ALITSTL 346 T+E +++ V++ G +D+++ NA + N + I + + + VN A + T+ Sbjct: 82 TSEADVKDLIDTAVRQHGRLDIMVANAGIANIKMSIEMTGAEWDQIMAVNTKGAFLCDTM 141 Query: 347 KAIEIMGK-HSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSK 517 A +++ + HS G GG +IN +S+AA + ++ Y A+K AV F+ + + K Sbjct: 142 AARQMIKQGHSETPGSGGKIINCASIAAHSGFSILAAYSASKFAVRGFTQALAKELGPYK 201 Query: 518 TGVRVLTVCFGATDTALLTDEKLGTF 595 V TD L DEK+G + Sbjct: 202 INVNAYCPGIVGTDMWTLIDEKMGPY 227 >UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=2; Euryarchaeota|Rep: Predicted short chain dehydrogenase - Methanosphaera stadtmanae (strain DSM 3091) Length = 253 Score = 77.8 bits (183), Expect = 2e-13 Identities = 58/206 (28%), Positives = 95/206 (46%), Gaps = 7/206 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K KV ITGA GIG+S+ + +EG I I E + + E+NS G+ + Sbjct: 4 KGKVAIITGATAGIGKSIAYLFAEEGASTILIARRKERL-EQITNEINSNGGDASACI-G 61 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 340 DVT +E ++ + + G ID+++NNA +M+D + + + K I+VN+T + Sbjct: 62 DVTKQEDIDNVVKLALDKYGKIDIIVNNAGIMDDFVSVKHIDDDLWDKTIDVNLTGPMRL 121 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 I M K++ GG +I +SSV L Y A+K V+ + + K Sbjct: 122 IRAVIPEMIKNN---GGNIITISSVGGLIGKISGAAYTASKHGVIGLAKHTAWV--YGKH 176 Query: 521 GVRVLTVCFGATDTALLTDEKLGTFD 598 +R + G +T + T G D Sbjct: 177 NIRSNVIAPGTVNTEIATTINPGRMD 202 >UniRef50_Q15Q07 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Gammaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 270 Score = 77.4 bits (182), Expect = 3e-13 Identities = 60/198 (30%), Positives = 98/198 (49%), Gaps = 9/198 (4%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K KV+ ITG ATGIG +V + + + + +D+ EEA +L +L+++ G F Sbjct: 26 KGKVILITGGATGIGAVMVEAFMRQQAR-VLFVDVQEEAAHALCSKLHAELGAAPIFKNL 84 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITS 340 D T+ + ++++ G +DV+INN A L D G ++ + VN+ + + Sbjct: 85 DTTHIDELQAFISSIGHSHGRLDVLINNVANDTRHSPLDIDQQG-WRDCMAVNLDSTFFA 143 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 AI +M + G +IN+SS+ L MP Y A KSA+ S + + + Sbjct: 144 CQSAIRLM---RDKRTGNIINMSSINVLIGPKQMPGYVAAKSALNGLSKSLA--NQYGEY 198 Query: 521 GVRVLTVCFG--ATDTAL 568 G+RV T+ G ATD L Sbjct: 199 GIRVNTILPGWVATDRQL 216 >UniRef50_Q9FX95 Cluster: ARP protein; n=8; Magnoliophyta|Rep: ARP protein - Arabidopsis thaliana (Mouse-ear cress) Length = 629 Score = 77.4 bits (182), Expect = 3e-13 Identities = 66/221 (29%), Positives = 105/221 (47%), Gaps = 20/221 (9%) Frame = +2 Query: 20 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGK---SLQVELNSKYGNKTKF-----Y 175 +TG A+GIG ++ L ++GV + + D +EE G+ SL E N+K+ F Sbjct: 11 VTGGASGIGRALCLALAEKGV-FVTVADFSEEKGQETTSLVREANAKFHQGLSFPSAIFV 69 Query: 176 RSDVTNEEHFLGILNAVVQEQGGIDVVINNAALMN---------DSIGIYKKAIEVNVTA 328 + DVTN L + + G +D+ INNA + D +K I V++ A Sbjct: 70 KCDVTNRGDLLAAFDKHLATFGTLDICINNAGISTPLRFDKDDTDGSKSWKHTINVDLIA 129 Query: 329 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEH 508 ++ T AI+ M K G +IN+ S A L V PIY A+K+ V+ F+ + + Sbjct: 130 VVEGTQLAIKAMKAKQ--KPGVIINMGSAAGLYPMPVDPIYAASKAGVVLFTRSLA---Y 184 Query: 509 FSKTGVRVLTVC--FGATDTALLTDEK-LGTFDKYLEFFML 622 + + G+R+ +C F TD A D L + Y+ ML Sbjct: 185 YRRQGIRINVLCPEFIKTDLAEAIDASILESIGGYMSMDML 225 >UniRef50_A5BP77 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 387 Score = 77.4 bits (182), Expect = 3e-13 Identities = 60/214 (28%), Positives = 105/214 (49%), Gaps = 20/214 (9%) Frame = +2 Query: 41 IGESVVRILLDEGVKHIAILDIAEEAGK---SLQVELNSKYGNK-----TKFYRSDVTNE 196 IG+++ L ++G+ + ++D +EE GK SL + N+K+ K F R DVTN Sbjct: 36 IGKAISLALGEKGI-FVTVVDFSEEGGKEVASLVEKENAKFHPKLGFPSAMFIRCDVTNT 94 Query: 197 EHFLGILNAVVQEQGGIDVVINNAAL---------MNDSIGIYKKAIEVNVTALITSTLK 349 + GG+D+ +N+A + ++ G++++ I VN+ A+I T Sbjct: 95 RELAAAFKKHLATYGGLDICVNSAGIGTHEPFHKDQTENSGLWRRTINVNLVAVIDCTRL 154 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 AI+ M + K G +IN+ S + L +V PIY A+K V+ F+ + + + G+R Sbjct: 155 AIQTM--QAAKKPGVIINMGSASGLYPMYVDPIYSASKGGVVLFTRSLA---PYKRHGIR 209 Query: 530 VLTVC--FGATDTALLTDEK-LGTFDKYLEFFML 622 V +C F T+ D K +G Y+ M+ Sbjct: 210 VNVLCPEFVQTEMGSSVDSKFIGLMGGYVSMEMV 243 >UniRef50_P54398 Cluster: Fat body protein 2; n=6; Schizophora|Rep: Fat body protein 2 - Drosophila melanogaster (Fruit fly) Length = 256 Score = 77.4 bits (182), Expect = 3e-13 Identities = 54/190 (28%), Positives = 94/190 (49%), Gaps = 2/190 (1%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAE--EAGKSLQVELNSKYGNKTKFYRS 181 K V G+ +GIG ++ L+ + +K + I+ E E K LQ +N K F + Sbjct: 7 KNVVYVGSFSGIGWQMMMQLMQKDIKMMGIMHRMENVEMMKKLQA-INPSV--KVVFMQM 63 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361 ++ + + + Q G IDV+IN ++ D + + +N+T +I ST+ A+ Sbjct: 64 NLMEKMSIEQAMKKMGQMMGHIDVMINGEGVLLDKD--VETTMGMNLTGMIQSTMMAMPY 121 Query: 362 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTV 541 M K G GG V+N+SSV L + +Y A +L F+ +G + KTGV + + Sbjct: 122 MDKTQMGMGGMVVNMSSVYGLEPAPAFAVYAAAMHGILGFTRSMGDKMIYQKTGVMFMAM 181 Query: 542 CFGATDTALL 571 C G T++ ++ Sbjct: 182 CPGLTNSEMI 191 >UniRef50_P19871 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=4; Burkholderiales|Rep: 3-beta-hydroxysteroid dehydrogenase - Comamonas testosteroni (Pseudomonas testosteroni) Length = 254 Score = 77.4 bits (182), Expect = 3e-13 Identities = 50/161 (31%), Positives = 89/161 (55%), Gaps = 6/161 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TG A+G+G VV++LL EG K +A DI E AG+ L EL G ++ F R DV Sbjct: 8 KVALVTGGASGVGLEVVKLLLGEGAK-VAFSDINEAAGQQLAAEL----GERSMFVRHDV 62 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTLK 349 ++E + ++ AV + G ++V++NNA ++ + + + +++N ++ + Sbjct: 63 SSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTESVFIGCQQ 122 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 472 I M + GG++IN++SV++ Y A+K+AV Sbjct: 123 GIAAMKE----TGGSIINMASVSSWLPIEQYAGYSASKAAV 159 >UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular organisms|Rep: Glucose 1-dehydrogenase - Oceanobacillus iheyensis Length = 256 Score = 77.0 bits (181), Expect = 4e-13 Identities = 59/197 (29%), Positives = 94/197 (47%), Gaps = 7/197 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 +DKV +TGAA G+G++ IL E + I D EE G+ + VE + G + F + Sbjct: 7 EDKVAIVTGAAMGMGKATA-ILFAESKAKVVIADFNEEKGQEV-VEEVKQAGGQAAFIKV 64 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITS 340 D+++ ++ V + G +D+ +NNAAL D + K I V++T T+ Sbjct: 65 DISDSAQVKQMVQFAVDQFGKLDIAVNNAALTPDDKPASEFDEDYWDKLISVDLTG--TA 122 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 E+ G GG+++N+SSV+ Y A K V+ + V E+ Sbjct: 123 LCMKYELQQLLEQGNGGSIVNISSVSGFRPQPNNIAYVAAKHGVVGMTK-VAALEN-GPQ 180 Query: 521 GVRVLTVCFGATDTALL 571 +RV TV GA DT +L Sbjct: 181 NIRVNTVAPGAIDTPML 197 >UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep: CylG - Streptococcus agalactiae Length = 240 Score = 77.0 bits (181), Expect = 4e-13 Identities = 52/197 (26%), Positives = 96/197 (48%), Gaps = 7/197 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TG GIG ++ + L EG K IAI + + ++LQ EL K Y+ ++ Sbjct: 2 KVAIVTGGTRGIGRAITKELYKEGYKVIAIYNSNDAKARALQEEL-----PKLDVYKCNI 56 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 349 ++ + ++ + +E GGID ++NNA ++ D + + I +N+ L+ + Sbjct: 57 SDAKAVQKLVTKIFREYGGIDCLVNNAGIVRDGFFLMMSKEKWMDVININIMGLVNMSKA 116 Query: 350 AIEIM-GKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 ++IM K GK VIN+SS + + Y ATK A++ + + + F+ G+ Sbjct: 117 VLKIMKAKRIQGK---VINISSTSGIAGQIGQANYSATKGAIISITKTLAK--EFASDGI 171 Query: 527 RVLTVCFGATDTALLTD 577 + V G +T + + Sbjct: 172 TINCVSPGFIETDMTNE 188 >UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammaproteobacteria|Rep: Short chain dehydrogenase - marine gamma proteobacterium HTCC2143 Length = 259 Score = 77.0 bits (181), Expect = 4e-13 Identities = 52/203 (25%), Positives = 92/203 (45%), Gaps = 5/203 (2%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 +V +TG A GIG + EG+ ++ + D+ ++ G+ + + GN F DV Sbjct: 8 QVALVTGGAAGIGRTTAAAFAREGL-NVVVADMDKDGGEETVAAIKAAGGNAI-FVPCDV 65 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 367 T E ++ G +D NNA + + G K E +++ +K + + Sbjct: 66 TKESDVQWLIETTCSTYGSVDYAFNNAGIDIEK-GELSKGTEDEFDSIMAVNVKGVWLCM 124 Query: 368 KHSGGK-----GGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532 KH + GGT++N SS+ L + M IY A+K AV+ + ++ G+R+ Sbjct: 125 KHQITQMITQGGGTIVNTSSIGGLGAAPNMSIYCASKHAVIGLTKSAAVEN--ARNGIRI 182 Query: 533 LTVCFGATDTALLTDEKLGTFDK 601 VC G DT + ++ FD+ Sbjct: 183 NAVCPGVIDTNMFNRSRM--FDR 203 >UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Candidatus Methanoregula boonei 6A8|Rep: Short-chain dehydrogenase/reductase SDR - Methanoregula boonei (strain 6A8) Length = 253 Score = 77.0 bits (181), Expect = 4e-13 Identities = 56/212 (26%), Positives = 98/212 (46%), Gaps = 6/212 (2%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV+ +TGA+ GIG + + + I + +SL E+ + G+ R+DV Sbjct: 12 KVILVTGASRGIGRATAFLAAKNHAQVIVNYQKHADQAESLVSEITA-LGHSAMAIRADV 70 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITSTLK 349 T EE + + ++ G +D+++NNA +M ++ I Y+ ++VN T Sbjct: 71 TCEEEVKEMFRQIREQYGRLDILVNNAGIMKNNLLMMTKIQEYQDVMDVNCKGTFLCTQH 130 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 A +IM + K GT+IN++SV + + Y ++KS V+ F+ C + + Sbjct: 131 AAKIMVRQ---KAGTIINLASVVGVYGNRGQSAYASSKSFVIGFTKCAAK--ELGAFNIT 185 Query: 530 VLTVCFGATDTALLTDEKLGTFDKYLEFFMLG 625 V V G DT L D + + L+ LG Sbjct: 186 VNAVAPGFIDTDLTADTRSQVKEDILKNIALG 217 >UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4; Brucellaceae|Rep: GLUCOSE 1-DEHYDROGENASE II - Brucella melitensis Length = 272 Score = 76.6 bits (180), Expect = 5e-13 Identities = 57/196 (29%), Positives = 94/196 (47%), Gaps = 6/196 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 KDKVV +TG A+GIGE+ R + EG K + I D ++ G+ L EL + + F ++ Sbjct: 4 KDKVVIVTGGASGIGEATARAFIREGAK-VVIADFSDH-GQQLADELAGAH-EQALFIKT 60 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITST 343 DV + ++ V+ G +D++ NA + D+ ++K I++N+T + Sbjct: 61 DVADTRAVQALIARTVENYGRLDIMFANAGIAADAPIDELDEAAWQKTIDINLTGVYLCD 120 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 AI+ M S G GG ++N S+ + + Y A K V + + + Sbjct: 121 KYAIDQM--RSQG-GGVIVNCGSIHSHVGKSGVTAYAAAKGGVKLLTQTLA--IDYGPQN 175 Query: 524 VRVLTVCFGATDTALL 571 +RV VC G DT LL Sbjct: 176 IRVNAVCPGYIDTPLL 191 >UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SDR) family protein; n=1; Thermobifida fusca YX|Rep: Short-chain dehydrogenase/reductase (SDR) family protein - Thermobifida fusca (strain YX) Length = 282 Score = 76.6 bits (180), Expect = 5e-13 Identities = 57/189 (30%), Positives = 91/189 (48%), Gaps = 5/189 (2%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 + +V ITG A+GIGE+ VR EG + I DI EAG+ L EL G++ F R+ Sbjct: 6 RGRVAAITGGASGIGEATVRRFHTEGAS-VVIADIQAEAGRRLADEL----GDRAVFVRT 60 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361 DV+ E +++ V G +D+++NNA +M ++G + I L+ + Sbjct: 61 DVSEEADVAALVDTAVDRFGQLDIMVNNAGIMG-ALGPIDATRMSDADLTIAVNLRGVIC 119 Query: 362 MGKHSG-----GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 KH+ + G +I+ SS A + IY A K ++ SN V + G+ Sbjct: 120 GMKHAARVMKPRRSGVIISTSSPAGVLGGIGPHIYSAVKVGIIGLSNSVA--AELRQHGI 177 Query: 527 RVLTVCFGA 553 RV T+ G+ Sbjct: 178 RVNTIIPGS 186 >UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 262 Score = 76.6 bits (180), Expect = 5e-13 Identities = 48/164 (29%), Positives = 84/164 (51%), Gaps = 7/164 (4%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 + KV ITG A GIG R L G +AILD+ + ++L E+ ++ G + F+ Sbjct: 11 RGKVAAITGGARGIGAETARTLAAAGAS-VAILDVLSQPAEALVEEIRAQ-GGQAAFWSL 68 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITS 340 DVT+E + +V G +DV++NNA + ++ +++ ++VNV + Sbjct: 69 DVTHEADVARVFGEIVAHFGRLDVLVNNAGIEGHNVPTHELTLAQWQRVLDVNVNGVFLC 128 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAV 472 T AI + GG+++N+SS+ + +P Y A+K+AV Sbjct: 129 TRAAIPHI---DAAGGGSIVNLSSMYGIVGGPDVPAYHASKAAV 169 >UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=3; Clostridium perfringens|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A) Length = 272 Score = 76.6 bits (180), Expect = 5e-13 Identities = 57/195 (29%), Positives = 96/195 (49%), Gaps = 7/195 (3%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 DKV+ ITGAA GIG++V EG K + + D EE K E+ N +F D Sbjct: 11 DKVMIITGAAGGIGKAVALRAAKEGAK-LVLADRKEEMSKETLKEIREITSN-VEFLICD 68 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITST 343 + E+ +++ +++ GG+D++INNA + S +++ ++ N+ + Sbjct: 69 LREGENCKKVIDTAIKKFGGLDILINNAGITGTPAPVHEMSEEMFRNVLDCNIMIAFHCS 128 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 I+ M K + KGG ++NVSSVA LT Y +K + + + +++ G Sbjct: 129 HYGIQEMIKQN--KGGAIVNVSSVAGLTGFPGHSAYVTSKHGLNGLTRNMAL--DYARYG 184 Query: 524 VRVLTVCFGATDTAL 568 +RV V G TDT + Sbjct: 185 IRVNAVNPGTTDTPM 199 >UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x; n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase FadB2x - Pseudomonas stutzeri (strain A1501) Length = 258 Score = 76.6 bits (180), Expect = 5e-13 Identities = 71/230 (30%), Positives = 106/230 (46%), Gaps = 18/230 (7%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 +DKVV ITG A+G+G + L E IAI D+ EAG+ L ++ + F + Sbjct: 4 QDKVVVITGGASGLGLATAHYLAAEKGARIAIFDLNVEAGEQAVAALGTE---RAMFVAT 60 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMND-----------SIGIYKKAIEVNVTA 328 DV++EE ++AV+ G I V IN AA+ + + +A +N+ Sbjct: 61 DVSSEESVQNAVDAVMANFGAIHVCINGAAVPTGFKILGKEGKAAPLARFAQATAINLNG 120 Query: 329 LITSTLKAIEIMGKH---SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGR 499 + K E M K+ +G + G VINVSS AA Y ATK+ V+ + R Sbjct: 121 VFNVMSKCAEHMAKNEAEAGEERGVVINVSSGAAYEGQLGQCAYSATKAGVIGLNMPAAR 180 Query: 500 PEHFSKTGVRVLTVC---FGATDTALLTDEKLGTFDKYLEF-FMLGPTKE 637 GVRV + F T A L ++ LG+ + +E LG T+E Sbjct: 181 --ELGAIGVRVNAIAPGLFLTTMVAALDEKVLGSLKEQMEAPKRLGDTRE 228 >UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Thermotoga|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Thermotoga maritima Length = 257 Score = 76.2 bits (179), Expect = 6e-13 Identities = 54/198 (27%), Positives = 94/198 (47%), Gaps = 8/198 (4%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K KV +TG GIG+++ + L G + I+DI EE + E+ K G + FY Sbjct: 11 KRKVALVTGGGQGIGKAIAQALAAAGAA-VLIMDINEETARRTVEEIKEK-GGEADFYVG 68 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 343 DVT EE G + + G +D+ +NNA + N + +KK I+VN+ + S Sbjct: 69 DVTKEEDCFGAVKKALDRWGKLDIGVNNAGIGDWCEAENYPVEKWKKVIDVNLVGVFLSA 128 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAA--LTQSHVMPIYFATKSAVLQFSNCVGRPEHFSK 517 M + GK +IN++S++ + + Y A+K+ V+ + + ++ Sbjct: 129 KAEFHAMKERKYGK---IINIASMSGHIVNKPQKQTAYNASKAGVIHLTRSLA--AEWAP 183 Query: 518 TGVRVLTVCFGATDTALL 571 G+RV ++ G T L+ Sbjct: 184 YGIRVNSISPGYIRTPLI 201 >UniRef50_Q97EW4 Cluster: Predicted short-chain dehydrogenase; n=6; Clostridium|Rep: Predicted short-chain dehydrogenase - Clostridium acetobutylicum Length = 262 Score = 76.2 bits (179), Expect = 6e-13 Identities = 51/188 (27%), Positives = 94/188 (50%), Gaps = 5/188 (2%) Frame = +2 Query: 14 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTN 193 V ITGA+TGIG + RI G + ++ +E K L +EL K + D++ Sbjct: 3 VLITGASTGIGYEITRIFARNG--YDVVITARDE--KRL-IELAKNINTKVTVIKKDLSR 57 Query: 194 EEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKH 373 + + N + + +D+++NNA M D+ G++ K+ + ++ +K++ I+ + Sbjct: 58 PDSANELFNEIKENNIEVDILVNNAG-MGDT-GLFHKSSVDKINEMLELNIKSLTILTRL 115 Query: 374 SGG-----KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538 + G ++NV+S + + +Y+ATK+ VL F+ +G E K V+V Sbjct: 116 VSAEMVKKRSGMILNVASTGSYMPGPFIAVYYATKAYVLSFTEAIG--EELKKFNVKVSA 173 Query: 539 VCFGATDT 562 +C GAT T Sbjct: 174 LCPGATAT 181 >UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Staphylococcus epidermidis|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 255 Score = 76.2 bits (179), Expect = 6e-13 Identities = 53/188 (28%), Positives = 101/188 (53%), Gaps = 7/188 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV + G ATGIG+++ L G +I I D+ G+ ++++ G KT + D+ Sbjct: 13 KVAMVIGGATGIGKAMAEALAQAGA-NIVIADLQSNIGQETATTISTQSGVKTTSLKLDI 71 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNA--ALMNDSIGI-YKKAI-EVNVTALITSTLKAI 355 T+ + I++ VV+E G ID+++NNA ++ +D+ I Y++ + E+N++ + Sbjct: 72 THSDEVNQIVDYVVREYGKIDILVNNASISIQDDTENISYEEWLKEINLS--LNGAFSVA 129 Query: 356 EIMGKHSGGKG-GTVINVSSVAAL--TQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 + +G+ KG G++INVSSV L ++ Y +K+ V + + R +S+ G+ Sbjct: 130 QTVGRQMIEKGSGSIINVSSVLGLIANKTQDQSSYETSKAGVTMLTKSLAR--EWSRYGI 187 Query: 527 RVLTVCFG 550 +V + G Sbjct: 188 KVNAIAPG 195 >UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase; n=1; Burkholderia xenovorans LB400|Rep: Putative short-chain type dehydrogenase - Burkholderia xenovorans (strain LB400) Length = 252 Score = 76.2 bits (179), Expect = 6e-13 Identities = 61/192 (31%), Positives = 91/192 (47%), Gaps = 6/192 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K + ITGA IG+ R + EG + + I DIAEEAG+++ EL G F + DV Sbjct: 8 KRIIITGAIGNIGKEAARGFIAEGAR-VVIGDIAEEAGRAVAAEL----GAAAHFVQVDV 62 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 367 T+E ++ V+ GG+D + NA L G + N AL +A Sbjct: 63 TSEASVANLIARGVEWLGGLDALAQNAGLQRS--GAIAGFEQANWDALFAVNARAHFFGA 120 Query: 368 KHS------GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 KH+ GK G++IN+SS+A + Y A+K AV+ F+ + + +R Sbjct: 121 KHAIPHLQRSGK-GSIINMSSLAGKRGGPGLVAYSASKGAVIAFTTALAL--ELAPDNIR 177 Query: 530 VLTVCFGATDTA 565 V +C G DTA Sbjct: 178 VNAICPGWVDTA 189 >UniRef50_Q2UEK6 Cluster: Dehydrogenases with different specificities; n=2; Aspergillus|Rep: Dehydrogenases with different specificities - Aspergillus oryzae Length = 261 Score = 76.2 bits (179), Expect = 6e-13 Identities = 56/203 (27%), Positives = 96/203 (47%), Gaps = 9/203 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TGA +GIG L + G ++ + + E GK +++++ G++ F +DV Sbjct: 13 KVAIVTGAGSGIGRETALCLANAGA-NVVVAEANETTGKETAAKVSAQTGSRGLFILTDV 71 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 346 + E ++ A ++ G +D+ +NNAAL D+ I ++K I VN+ + L Sbjct: 72 SRSESVQAMVIATIEAFGRLDIAVNNAALHPDASPIAELHEDHWQKIIGVNLVG-VAFCL 130 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 K E+ G GG++IN+SS M Y A K + + + G+ Sbjct: 131 K-WELQQMIQQGGGGSIINISSATINRPQEKMSAYIAAKHGITGLTQTAAVEN--GRHGI 187 Query: 527 RVLTVCFG--ATDTALLTDEKLG 589 RV + G ATD + T ++LG Sbjct: 188 RVNALAPGGVATDLTMATMQELG 210 >UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase, putative glucose-1-dehydrogenase; n=1; Pyrococcus abyssi|Rep: Short-chain alcohol dehydrogenase, putative glucose-1-dehydrogenase - Pyrococcus abyssi Length = 240 Score = 76.2 bits (179), Expect = 6e-13 Identities = 58/200 (29%), Positives = 97/200 (48%), Gaps = 7/200 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K KV ITGA+ GIG ++ L GV + EE K + EL +YG +T ++ Sbjct: 4 KGKVALITGASRGIGRAIAIELAKRGVNVVINYRSNEEEAKKTE-ELCRQYGVETLLVKA 62 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALM---NDSIGI----YKKAIEVNVTALITS 340 DV+N E ++ V+ + G ID++INNA ++ D + + + + I VN+ Sbjct: 63 DVSNREEVREMVKKVIDKFGRIDILINNAGILGKTKDPLEVTDEEWDRVISVNLKGAFIV 122 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 T + + M K G ++N++S+A V P Y A+K ++ + + R H + Sbjct: 123 TQEVLRYM------KKGKIVNIASIAGKDGGTVGPHYAASKGGLIALTFNLAR--HLA-P 173 Query: 521 GVRVLTVCFGATDTALLTDE 580 + V V G DT +L+ E Sbjct: 174 NILVNAVAPGPVDTDMLSSE 193 >UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=4; Sphingomonas|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Pseudomonas paucimobilis (Sphingomonas paucimobilis) Length = 250 Score = 76.2 bits (179), Expect = 6e-13 Identities = 61/193 (31%), Positives = 94/193 (48%), Gaps = 6/193 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV ITG A+G+G + + +EG K + I D+ EE K + E+ + G F R DV Sbjct: 8 KVALITGGASGLGAAQAKRFAEEGAK-VVIGDLNEEMAKGVVAEIRAA-GGDALFIRLDV 65 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 349 T+ + + A V GG+ + N A +++ +SI + K + VN TA+ Sbjct: 66 TDAASWNNAIAAAVDGFGGLTTLSNTAGIIHPGGFEEESIEGWNKMVAVNQTAIFLGIKA 125 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 AI + K SG G++IN+SS+ + + Y ATK+AV S F GVR Sbjct: 126 AIPELVK-SG--NGSIINISSLIGMFPTAGNASYCATKAAVRIMSKAAAL--EFVDRGVR 180 Query: 530 VLTVCFGATDTAL 568 V T+ G +T + Sbjct: 181 VNTIVPGGMNTPI 193 >UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=225; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Vibrio cholerae Length = 244 Score = 76.2 bits (179), Expect = 6e-13 Identities = 60/201 (29%), Positives = 97/201 (48%), Gaps = 9/201 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TGA+ GIG+++ +L + G K I E+G ++ G+ K +V Sbjct: 6 KVALVTGASRGIGKAIAELLAERGAKVIGTA--TSESGAQA---ISDYLGDNGKGMALNV 60 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK------AIEVNVTALITSTLK 349 TN E +L A+ E GG+D+++NNA + D++ + K +E N+T++ + Sbjct: 61 TNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLSKA 120 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 + M K + G +INV SV + Y A K+ V+ F+ + R + GV Sbjct: 121 VLRGMMKK---RQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAR--EVASRGVT 175 Query: 530 VLTVC--FGATD-TALLTDEK 583 V TV F TD T L DE+ Sbjct: 176 VNTVAPGFIETDMTKALNDEQ 196 >UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20; Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase - Oceanobacillus iheyensis Length = 255 Score = 75.8 bits (178), Expect = 8e-13 Identities = 65/202 (32%), Positives = 100/202 (49%), Gaps = 13/202 (6%) Frame = +2 Query: 20 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTNEE 199 +TG A+G+GE+ VR L ++G K +AI D+ +E G+ L EL G+ +++ DVT+E Sbjct: 10 VTGGASGLGEATVRRLHNQGGK-VAIFDLNKENGERLATEL----GDNVDYFQVDVTDET 64 Query: 200 HFLGILNAVVQEQGGIDVVINNA--ALMNDSIG--------IYKKAIEVNVTALITSTLK 349 L+ V+++ GI V+N A A+ +IG + IE+N+ Sbjct: 65 SVQKALDNVMEQSDGIHAVVNCAGIAIAEKTIGKKGVHSLQHFSNVIEINLIGTFNVIRL 124 Query: 350 AIEIMGKHS---GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 A E M +S G+ G +IN +SVAA Y A+K V + + R S Sbjct: 125 AAEKMALNSPNDEGERGVIINTASVAAFEGQIGQAAYSASKGGVAGMTLPIAR--DLSTL 182 Query: 521 GVRVLTVCFGATDTALLTDEKL 586 G+RV+T+ G T L EKL Sbjct: 183 GIRVMTIAPGLFLTPLF--EKL 202 >UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reductase; n=3; Proteobacteria|Rep: 3-ketoacyl-acyl carrier protein reductase - Pseudoalteromonas haloplanktis (strain TAC 125) Length = 247 Score = 75.8 bits (178), Expect = 8e-13 Identities = 57/198 (28%), Positives = 96/198 (48%), Gaps = 6/198 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 +D+VV +TGA GIG+S+V G ++A +DI + + ELN+ + Sbjct: 4 QDQVVLVTGAGQGIGQSIVSYFATAGA-NVAAVDINADTLNASVNELNANVAGNIVAITA 62 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITST 343 ++ + + AVV++ G +D +IN A A ++ + K I VN+T Sbjct: 63 NIAKSDSVRDAIAAVVEKFGRLDAIINVAGVGSIDAFVDTPDEHWDKVIAVNLTGTFLCC 122 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 +A ++M G +INVSS AALT Y A+K+ V+ + + R + G Sbjct: 123 REAAKVMQAQG---SGCIINVSSTAALT-GEGPSHYCASKAGVMGLTRSMAR--ELAPVG 176 Query: 524 VRVLTVCFGATDTALLTD 577 +RV T+ G T+T ++ D Sbjct: 177 IRVNTIVPGPTNTPMMAD 194 >UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reductase; n=1; Bacillus sp. SG-1|Rep: 3-oxoacyl-(Acyl-carrier-protein) reductase - Bacillus sp. SG-1 Length = 246 Score = 75.8 bits (178), Expect = 8e-13 Identities = 55/195 (28%), Positives = 96/195 (49%), Gaps = 6/195 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K+K ITG+A GIG + + EG K + + D E G + + E + G T FY+ Sbjct: 4 KNKTAVITGSANGIGLAAAKKFAQEGCK-VIMADYDENKGAA-EAEKLQEEGGDTVFYQV 61 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITST 343 DV N E + V+++ G ID++INNA + D++ +++ ++VN+T + T Sbjct: 62 DVANRESVDNLAAWVLRDYGSIDILINNAGITRDALMAKMREDDFQRVLDVNLTGVFHCT 121 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 + + + GK G +IN +S + L + Y A+K+AV+ + + F G Sbjct: 122 QALLPAL--INSGK-GKIINTASASGLYGNVGQTNYAASKAAVIGMTKTWAK--EFGPKG 176 Query: 524 VRVLTVCFGATDTAL 568 + V V G +T + Sbjct: 177 INVNAVAPGVIETEM 191 >UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Marinomonas sp. MED121|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MED121 Length = 255 Score = 75.8 bits (178), Expect = 8e-13 Identities = 60/206 (29%), Positives = 100/206 (48%), Gaps = 7/206 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 KD+VV ITGA+ G+G+ + +G K +A+ D+ A L EL + G + Sbjct: 5 KDQVVLITGASGGLGKEAAKQFAQQGAK-LALCDLNVAALNDLGTELIEQ-GYEVFSQPC 62 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITS 340 DV+NE+ ++ G +DV INNA L + +++ +++NV + Sbjct: 63 DVSNEQEVQSFIDNTAAHFGRLDVAINNAGIDPKHSTLADMDTRDFERVMDINVKGVYLC 122 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 I M K GG + N+SSVA ++ + M Y A+K AV+ + V + + Sbjct: 123 MKYQIPHMIKQGGG---AICNMSSVAGISGAPFMSAYAASKHAVIGLTKSVA--HEYGRA 177 Query: 521 GVRVLTVCFGATDTALLTDEKLGTFD 598 G+RV +VC T T ++ ++ L T D Sbjct: 178 GIRVNSVCPYITMTDMV-EQHLKTLD 202 >UniRef50_A1UMZ0 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=5; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR precursor - Mycobacterium sp. (strain KMS) Length = 261 Score = 75.8 bits (178), Expect = 8e-13 Identities = 57/200 (28%), Positives = 93/200 (46%), Gaps = 8/200 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 +V +TG A+GIG + L EG++ + +LDI A +++ + G R DV Sbjct: 6 RVALVTGGASGIGRATAGRLAAEGMR-VCVLDIDGPATEAVAESIGG-IG-----LRCDV 58 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMND---SIGI-----YKKAIEVNVTALITST 343 T+ E + V E GG+DV NA + D IG Y+K++ VNV ++ Sbjct: 59 TDPEQVDSAFDTCVAELGGVDVAFLNAGITIDWSGDIGALDLAQYRKSVGVNVDGVVFGV 118 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 A+ M G ++ +S+A L H P+Y K V+ F + + + G Sbjct: 119 RAAVRTMRTLDPGVDRAILATASLAGLMPWHPDPVYSLGKHGVVGFMRSIA--PNLAAEG 176 Query: 524 VRVLTVCFGATDTALLTDEK 583 + V T+C G T+T +L D + Sbjct: 177 IAVHTICPGITETGVLGDRR 196 >UniRef50_A0X2J5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Shewanella pealeana ATCC 700345|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella pealeana ATCC 700345 Length = 254 Score = 75.8 bits (178), Expect = 8e-13 Identities = 55/184 (29%), Positives = 97/184 (52%), Gaps = 6/184 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV ITGAA G+G + R++ EG + + + DI E GK E+ + GN + F DV Sbjct: 8 KVALITGAARGVGLATARLMAREGAQ-VVLTDINAEQGK----EIANSIGNNSLFIEHDV 62 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTLK 349 T E + ++N + + G +++++NNAA++ +++ +++ VN ++ Sbjct: 63 TKEADWSAVINHIEAKFGQLNILLNNAAILQLGDIKEETLAGWQRVHMVNSDSVFLRIHY 122 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 A+ +M K SG GG++IN+SS +A+ Y A+K+A+ S V +K VR Sbjct: 123 ALPLMEK-SG--GGSIINMSSSSAVFGMPHFAAYGASKAAIRGLSQSVAVYCSQTKNNVR 179 Query: 530 VLTV 541 T+ Sbjct: 180 CNTL 183 >UniRef50_A0LZZ5 Cluster: Short-chain dehydrogenase/reductase family protein; n=1; Gramella forsetii KT0803|Rep: Short-chain dehydrogenase/reductase family protein - Gramella forsetii (strain KT0803) Length = 271 Score = 75.8 bits (178), Expect = 8e-13 Identities = 52/200 (26%), Positives = 102/200 (51%), Gaps = 6/200 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 ++K V ITG A+GIG + + +++G + ILDI + A + ++++L + F + Sbjct: 5 RNKTVLITGGASGIGLLLTKFSIEKGASALIILDIDKPALQQVELQLKTNICQILSF-ET 63 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITST 343 D++NE + + + +D++INNA ++ ++ + ++VN A + T Sbjct: 64 DLSNEIQIENAVKKITAQNLQVDILINNAGVVTGKNFSEHNLEDIDRNMQVNAIAPMKLT 123 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 + M K K G ++N+SS A++ + M +Y A+K A+ +S+ + +TG Sbjct: 124 KLLLPEMLKR---KSGHIVNISSAASMLSNPGMSVYCASKWAMTGWSDSLRLEMERERTG 180 Query: 524 VRVLTVCFGATDTALLTDEK 583 ++VLTV DT + K Sbjct: 181 IKVLTVTPYYIDTGMFEGVK 200 >UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Chloroflexus|Rep: Short-chain dehydrogenase/reductase SDR - Chloroflexus aggregans DSM 9485 Length = 256 Score = 75.8 bits (178), Expect = 8e-13 Identities = 58/194 (29%), Positives = 95/194 (48%), Gaps = 6/194 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TG A GIG + L EG + I D + A + VE + +G + +DV Sbjct: 6 KVAIVTGGAQGIGRATALALAREGAA-VVIAD-RDAAATTALVEGINAWGGRALAVIADV 63 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTLK 349 ++E I N V E GGID+++NNA + + ++ ++++ I VN+T + L Sbjct: 64 SDESDAARIANDTVLEFGGIDLLVNNAGIQQPGTIESTTLQLWQEIINVNLTGVF---LV 120 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 + +M + GG ++NV+SV L Y A+K V+ + + + G+R Sbjct: 121 SRFVMPELRRRGGGAIVNVASVYGLRAEAGWAAYAASKGGVIALTRAMALDG--APDGIR 178 Query: 530 VLTVCFGATDTALL 571 V VC G DT+LL Sbjct: 179 VNCVCPGLIDTSLL 192 >UniRef50_Q22CU9 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Tetrahymena thermophila SB210 Length = 843 Score = 75.8 bits (178), Expect = 8e-13 Identities = 57/192 (29%), Positives = 94/192 (48%), Gaps = 6/192 (3%) Frame = +2 Query: 14 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTN 193 V +TGAA G G+ + + +I I DI E+ + E+ K G K FY+ DV++ Sbjct: 577 VLLTGAAMGAGKFLAMNFAKKNNCNIIIYDIREDLMGQVIEEIQ-KAGAKGYFYKCDVSD 635 Query: 194 EEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLKAI 355 E+ + + +Q+ ID++INN + N S +KA VN A ++ K + Sbjct: 636 EQELQRTVESTLQKFQKIDILINNVGIANLKLFTDVSFDEVQKAFSVNFLAPVSIIKKIL 695 Query: 356 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535 +M + + G ++NVSSVA+L S M Y A+K+A+ F N + K + Sbjct: 696 PVMIERNQGH---IVNVSSVASLMPSAKMTDYCASKAALSGFHNALRLELKQQKKNINTT 752 Query: 536 TVCFGATDTALL 571 +C A +T +L Sbjct: 753 LICPYAVNTGVL 764 >UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplast precursor; n=80; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplast precursor - Arabidopsis thaliana (Mouse-ear cress) Length = 319 Score = 75.8 bits (178), Expect = 8e-13 Identities = 60/198 (30%), Positives = 97/198 (48%), Gaps = 8/198 (4%) Frame = +2 Query: 11 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELN-SKYGNKTKFYRSDV 187 VV ITGA+ GIG+++ L G K +++ A A ++ +V +YG + + DV Sbjct: 78 VVVITGASRGIGKAIALALGKAGCK--VLVNYARSAKEAEEVAKQIEEYGGQAITFGGDV 135 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 349 + ++ + + G IDVV+NNA + D++ I + + I +N+T + T Sbjct: 136 SKATDVDAMMKTALDKWGTIDVVVNNAGITRDTLLIRMKQSQWDEVIALNLTGVFLCTQA 195 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 A++IM K K G +IN+SSV L + Y A K V+ FS R V Sbjct: 196 AVKIMMKK---KRGRIINISSVVGLIGNIGQANYAAAKGGVISFSKTAAREGASRNINVN 252 Query: 530 VLTVCFGATD-TALLTDE 580 V+ F A+D TA L ++ Sbjct: 253 VVCPGFIASDMTAELGED 270 >UniRef50_UPI0000E465C5 Cluster: PREDICTED: similar to MGC80593 protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to MGC80593 protein - Strongylocentrotus purpuratus Length = 258 Score = 75.4 bits (177), Expect = 1e-12 Identities = 55/186 (29%), Positives = 91/186 (48%), Gaps = 7/186 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 + V ITG+A G+G + + G + + +LDI E K L EL SK G Y D+ Sbjct: 63 RTVLITGSANGLGRLLAQEFARRGAQ-LVLLDIDIEGNKLLAEELCSK-GRSAHAYYCDL 120 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 349 + + ++ + ++ G +D++INNAA ++ S +K EVN A I T Sbjct: 121 SRKTDLYSVIAQIKRDIGHVDILINNAATLSGKPVLQCSDSAIEKVFEVNTMAYIWLTKA 180 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVG-RPEHFSKTGV 526 + M K G V+N++S+A + + Y A+KSA++ F+ +G + TGV Sbjct: 181 LLPDMLNR---KQGHVVNIASLAGFVGVNGLADYCASKSAIIGFTEALGYELKQMKATGV 237 Query: 527 RVLTVC 544 + VC Sbjct: 238 HLSLVC 243 >UniRef50_A4XF64 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Novosphingobium aromaticivorans (strain DSM 12444) Length = 266 Score = 75.4 bits (177), Expect = 1e-12 Identities = 56/191 (29%), Positives = 90/191 (47%), Gaps = 4/191 (2%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 ++ +TGAA GIGE + R EG + + D +E G ++ +L G + +F R D Sbjct: 8 NRAAVVTGAADGIGEGIARRFAAEGAA-VVVADYDDERGPAVARDLRG-LGARAEFIRCD 65 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTAL---ITSTLKAI 355 V+ E +G ++ V+ G +D+++NNA + I KK E AL + +T A+ Sbjct: 66 VSRREDVIGAVDLCVERFGSVDILVNNAYRGEGPVRIEKKTDERFDEALRMCLFATKWAM 125 Query: 356 EIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532 E H KG G VIN++S+ + Y K AV +S R ++ G+ V Sbjct: 126 ERALPHMKAKGWGRVINMASLNGVNAHMGSADYNVAKEAVRAYSRTAAR--EWAPYGICV 183 Query: 533 LTVCFGATDTA 565 +C A A Sbjct: 184 NVICPAAVSAA 194 >UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=4; Shewanella|Rep: Short-chain dehydrogenase/reductase SDR precursor - Shewanella sp. (strain ANA-3) Length = 292 Score = 75.4 bits (177), Expect = 1e-12 Identities = 53/200 (26%), Positives = 97/200 (48%), Gaps = 7/200 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEA-GKSLQVELNSKYGNKTKFYR 178 K KV ITG+ +GIG + +L ++G H+ + + EA G+ L E +Y T F Sbjct: 35 KGKVGLITGSTSGIGLATAHVLAEQGC-HLILHGLMPEAEGRRLAAEFAEQYHIHTYFSN 93 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITS 340 +D+ + E ++A V+ G ID+++NNA + + I + I +N+++ + Sbjct: 94 ADLRDPESIHAFMDAGVKALGSIDILVNNAGIQHTENVAHFPIDKWNDIIAINLSSAFHT 153 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 +A+ M + + G +IN++SV L S Y A K ++ + V ++ Sbjct: 154 IQQAVPAMAEK---RWGRIINIASVHGLVASVNKAAYCAAKHGIVGLTKVVA--IECAEQ 208 Query: 521 GVRVLTVCFGATDTALLTDE 580 G+ V +C G DT L+ + Sbjct: 209 GITVNAICPGWVDTPLINKQ 228 >UniRef50_Q82FK0 Cluster: Putative dehydrogenase; n=2; Streptomyces|Rep: Putative dehydrogenase - Streptomyces avermitilis Length = 584 Score = 74.9 bits (176), Expect = 1e-12 Identities = 54/194 (27%), Positives = 97/194 (50%), Gaps = 9/194 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS-D 184 ++V +TGA +GIG + + G + +A+ AE A ++ E++ G + + D Sbjct: 317 QLVLVTGAGSGIGRATAYAFAEAGARVVAVDRNAEGAART--AEMSRLIGAPDAWAETVD 374 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTL 346 V++E+ + V E G +DV++NNA + + + ++K ++VN+ +I Sbjct: 375 VSDEQAMEKLAEKVATEYGVVDVLVNNAGIGLSGSFFDTTAEDWRKVLDVNLWGVI---- 430 Query: 347 KAIEIMGKHSG--GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 + GK G+GG ++N +S AA S +P Y +K+AVL S C+ R E + Sbjct: 431 HGCRLFGKQMAERGQGGHIVNTASAAAYQPSKALPAYSTSKAAVLMLSECL-RAE-LAGQ 488 Query: 521 GVRVLTVCFGATDT 562 G+ V +C G T Sbjct: 489 GIGVSAICPGFVHT 502 >UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=17; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Chromobacterium violaceum Length = 246 Score = 74.9 bits (176), Expect = 1e-12 Identities = 55/196 (28%), Positives = 95/196 (48%), Gaps = 6/196 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K KV ITG+A+GIG++ + EG +A+ D+ +A K++ EL + G + Y+ Sbjct: 4 KGKVSIITGSASGIGKATAEKFVKEGAI-VAVCDLNPDAVKTVVDELKA-LGGEAYGYKV 61 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 343 DVT++ ++ + G IDV++NNA ++ D+ I + K I++N+ + Sbjct: 62 DVTDKGQIAEMVADLKNRCGRIDVLVNNAGIVQDAQLIKMSEDQFDKVIDINLKGVYNCA 121 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 ++ M + GG ++N SSV + + Y A K V+ F + K G Sbjct: 122 RAVVDTMVEQG---GGVILNASSVVGVYGNFGQTNYAAAKFGVIGFVKTWAK--ELGKKG 176 Query: 524 VRVLTVCFGATDTALL 571 +R VC G T +L Sbjct: 177 IRANAVCPGFVATPIL 192 >UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain KSM-K16) Length = 257 Score = 74.9 bits (176), Expect = 1e-12 Identities = 53/189 (28%), Positives = 101/189 (53%), Gaps = 8/189 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K +TG A G+G ++ + L G IAI+DI EA E+ + Y T+ ++DV Sbjct: 12 KHAVVTGGAQGLGFTIAKSLAAFGCD-IAIVDIDAEAAAKAAQEITTTYSVNTQSIQADV 70 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMN--DSIGI----YKKAIEVNVTALITSTLK 349 + EE +++ V++ IDV++NNA ++ D++ + +K+ ++VN+ AL ++ + Sbjct: 71 SKEEEVSAMVDRVLESFPQIDVLVNNAGIVKKIDTLDMTYSDWKRTMDVNINALFLTSKQ 130 Query: 350 AIEIMGKHSGGKG-GTVINVSSVAA-LTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 +GKH G G+++N+SS++A + Y A+K AV + + +++ G Sbjct: 131 ----VGKHMVANGSGSIMNMSSMSAMIANREAQSAYNASKGAVSMLTKSLA--SEWAQYG 184 Query: 524 VRVLTVCFG 550 +RV + G Sbjct: 185 IRVNAIAPG 193 >UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 256 Score = 74.9 bits (176), Expect = 1e-12 Identities = 58/200 (29%), Positives = 94/200 (47%), Gaps = 10/200 (5%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 +D+V ITGAA+G G + ++ EG K +A DI +E G VE + G + + Sbjct: 4 EDRVAVITGAASGQGRAAAKLFASEGAKVVAA-DI-DEGGAQRTVEEIKEAGGEATAVKV 61 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNV-----TALITSTL 346 DV+ E ++ + G +DV+ NNA + + G K A V A++ L Sbjct: 62 DVSREPDVRAMVESATDRYGRLDVLFNNAGVGYSASGRMKMASVVETPEKDWDAILAINL 121 Query: 347 KAIEIMGKHS----GGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHF 511 K + + KH+ +G G++IN +S+ AL Y A K V+ FS + + Sbjct: 122 KGVALGCKHAIPVMERQGYGSIINNASINALVGLPGADAYTAAKGGVVAFSRVLA--VEW 179 Query: 512 SKTGVRVLTVCFGATDTALL 571 G+RV +C G DT ++ Sbjct: 180 GPRGIRVNCICPGGVDTPMI 199 >UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Mesorhizobium sp. BNC1|Rep: Short-chain dehydrogenase/reductase SDR - Mesorhizobium sp. (strain BNC1) Length = 257 Score = 74.9 bits (176), Expect = 1e-12 Identities = 55/192 (28%), Positives = 94/192 (48%), Gaps = 5/192 (2%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS-D 184 KV +TGAA G+GE++ L +G + +A+LD+ +E G + + GN +YR+ D Sbjct: 7 KVALVTGAARGLGEAIAVELAAQGAR-VALLDVLDELGAEVAENIKKSSGN--AYYRNCD 63 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEV--NVTALITSTLKAI- 355 + + E ++ V G +DV++NNAA+ I + + E N+ + S++ Sbjct: 64 IRDTEEVRSAVDEVYSTYGKLDVLVNNAAVSTAPTSIPELSEETWNNIFNVNVSSIYRFC 123 Query: 356 -EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532 ++ + GG VIN+SSV Y ATK A++ S + + + +RV Sbjct: 124 RFVLPRMQEAGGGAVINMSSVHQSHSLTGWTAYAATKGAIISMSRQLA--AEWGRFNIRV 181 Query: 533 LTVCFGATDTAL 568 TV GA D + Sbjct: 182 NTVSPGAIDATM 193 >UniRef50_A1SPQ9 Cluster: Short-chain dehydrogenase/reductase SDR; n=19; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 246 Score = 74.9 bits (176), Expect = 1e-12 Identities = 55/193 (28%), Positives = 92/193 (47%), Gaps = 6/193 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K+ +TGA GIG+++ L EG + + D+ +A K L+ + +DV Sbjct: 7 KIAVVTGAGQGIGKAIATKLAAEGAT-VVVTDVDHQAAKETAAALD----HGAIGLHADV 61 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITSTLK 349 T+ +++ VV G IDV++NNA A ++ + + I +N+ ++ ++ K Sbjct: 62 TDRTSVDAMVDEVVATFGRIDVLVNNAGWDKGEAFVDSEPETWDRIIGINLYGVLNTSKK 121 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 + IM G+V+N+ S A S +Y A K V+ FS R +++ V Sbjct: 122 VLPIMAAQG---SGSVVNIGSDAGRVGSSGEAVYSAAKGGVIAFSKATAR--EMARSQVN 176 Query: 530 VLTVCFGATDTAL 568 V VC G TDTAL Sbjct: 177 VNCVCPGPTDTAL 189 >UniRef50_A0HI81 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Comamonas testosteroni KF-1 Length = 259 Score = 74.9 bits (176), Expect = 1e-12 Identities = 57/191 (29%), Positives = 92/191 (48%), Gaps = 6/191 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 + ITGA GIG + + EG + + AE ++ + L + G + +DV Sbjct: 9 RTALITGAGAGIGAAASHLFCKEGAAVLMVDANAEALERTREAILQAVPGARLACVMADV 68 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE------VNVTALITSTLK 349 ++E + VQ+ GG+D ++NNAA+ N S A E VN+ + Sbjct: 69 SDESAAAAAVGQCVQQWGGLDTLVNNAAMRNYSAAADATAAEWQAMVGVNLVGMSNYCRA 128 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 A+ + + SG G+++NVSS A+T M +Y ATK+A L ++ + E + GVR Sbjct: 129 ALPAL-RQSG--TGSIVNVSSCYAVTGRKGMALYDATKAAQLAYTRSLAFEE--AAHGVR 183 Query: 530 VLTVCFGATDT 562 VC G+T T Sbjct: 184 ANAVCPGSTLT 194 >UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 284 Score = 74.9 bits (176), Expect = 1e-12 Identities = 67/220 (30%), Positives = 100/220 (45%), Gaps = 19/220 (8%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE--EAGKSLQVELNSKYGNKTKFYR 178 DKV ITG++ GIG++ R+L EG K AE E K++ + GN Sbjct: 6 DKVAIITGSSNGIGQATARLLASEGAKVTVTGRNAERLEETKNILLGAGVPEGN-VLVVV 64 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAAL----------MNDSIGIYKKAIEVNVTA 328 D+T E ++ + + + G ID+++NNA +N SI Y K E+NV + Sbjct: 65 GDITQESVQENLIKSTLDKFGKIDILVNNAGAGIPDAQGKSGVNQSIDTYHKTFELNVQS 124 Query: 329 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHV-MPIYFATKSAVLQFSNCVGRPE 505 +I T KA H G ++N+SS+ A + V P Y K+A+ Q++ Sbjct: 125 VIEMTQKA----RPHLAKTQGEIVNISSIGAGPAAQVASPYYSIAKAALDQYTRTAA--I 178 Query: 506 HFSKTGVRVLTVCFGATDTAL------LTDEKLGTFDKYL 607 G+RV +V GA T LT+EK F YL Sbjct: 179 DLVPEGIRVNSVSPGAVSTGFSAVSRGLTEEKSKAFYDYL 218 >UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019; n=11; cellular organisms|Rep: Uncharacterized oxidoreductase TM_0019 - Thermotoga maritima Length = 256 Score = 74.9 bits (176), Expect = 1e-12 Identities = 52/192 (27%), Positives = 96/192 (50%), Gaps = 6/192 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TG GIG ++ ++ + G+K + I +I EEAG + L + G F ++DV Sbjct: 5 KVAVVTGGGQGIGAAIAQLFAENGMK-VVIAEIDEEAGVEREEMLRER-GLDVTFVKTDV 62 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 349 +E ++ V+ GG+DV++NNAA+M+ + +++ I VN+T + Sbjct: 63 ADENSVKNMVRKTVEIYGGVDVLVNNAAVMSVKSIFERPLEEWERVIRVNLTGPYICSRY 122 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 E M K GG +IN++S A Y A+K ++ ++ + S+ +R Sbjct: 123 CAEEMIKRG---GGVIINIASTRAFQSEPDTEPYSASKGGLVALTHSLA--VSLSRYHIR 177 Query: 530 VLTVCFGATDTA 565 V+++ G +T+ Sbjct: 178 VVSISPGWIETS 189 >UniRef50_Q71R50 Cluster: Dehydrogenase/reductase SDR family member 11 precursor; n=7; Eukaryota|Rep: Dehydrogenase/reductase SDR family member 11 precursor - Gallus gallus (Chicken) Length = 255 Score = 74.9 bits (176), Expect = 1e-12 Identities = 54/193 (27%), Positives = 94/193 (48%), Gaps = 8/193 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 +V +TGA+ GIG +V R L+ G+K + ++ K ++ Y Y+ D+ Sbjct: 7 RVALVTGASVGIGAAVARALVQHGMKVVGCARSVDKIEKLAAECQSAGYPGTLIPYKCDL 66 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLK 349 +NEE L + +A+ G+DV INNA L++ ++ I+VNV A+ T + Sbjct: 67 SNEEEILSMFSAIKTLHQGVDVCINNAGLARPEPLLSGKTEGWRTMIDVNVMAVSICTRE 126 Query: 350 AIEIMGKHSGGKGGTVINVSSV--AALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 A + M K G +IN++S+ ++ V+ Y ATK AV + + + +KT Sbjct: 127 AYQSM-KERNIDDGHIININSMNGHSVVPQSVVHFYSATKYAVTALTEGLRQELREAKTH 185 Query: 524 VRVLTVCFGATDT 562 +R + G +T Sbjct: 186 IRATCISPGLVET 198 >UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n=2; Proteobacteria|Rep: 2O-beta-hydroxysteroid dehydrogenase - Pseudoalteromonas haloplanktis (strain TAC 125) Length = 262 Score = 74.5 bits (175), Expect = 2e-12 Identities = 55/202 (27%), Positives = 99/202 (49%), Gaps = 6/202 (2%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 +KV +TGAA GIG ++ + L+D G IA + EE + Q + G+K D Sbjct: 9 NKVALVTGAARGIGRAICQALVDSGATVIATDILTEELNQMAQ-----ELGDKVTPMTHD 63 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 346 VT+E + I++A +++ ID+++NNA ++ ++K I++N+T Sbjct: 64 VTDELQWQSIVSATLEKHQKIDILVNNAGILLFATLETTEPQQFRKLIDINITGTFLGLH 123 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 I M K +G G ++N+SS +++ ++ Y A+K AV + G+ Sbjct: 124 SVIPCM-KKAG--SGAIVNISSASSILPNNGTGAYAASKYAVRGLTRTAAL--ELGPFGI 178 Query: 527 RVLTVCFGATDTALLTDEKLGT 592 RV +V GA +T + + L + Sbjct: 179 RVNSVHPGAVNTPMTNPQGLSS 200 >UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 250 Score = 74.5 bits (175), Expect = 2e-12 Identities = 47/169 (27%), Positives = 89/169 (52%), Gaps = 7/169 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TGAA GIG ++ + EG K + I DI + G+ + EL G + F+ +DV Sbjct: 10 KVAIVTGAANGIGVAIATRFVTEGAK-VVIADI-DAGGQGVAAEL----GERATFFSTDV 63 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNVTALITSTL 346 ++ +++ ++ GG+ V+ NNA + ++D + +++ + V++ ++ + Sbjct: 64 SDPVQTQALVDFTIRHFGGLHVLCNNAGVSGGLRRFLDDDLRDFERVVAVDLYGVMACSR 123 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCV 493 A M H GG ++N++S A +T M Y A K+ V+QF+ C+ Sbjct: 124 SAARHMVDHGGG---AIVNIASGAGITPGIGMLPYRAAKAGVVQFTRCL 169 >UniRef50_Q1IIJ1 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Acidobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Acidobacteria bacterium (strain Ellin345) Length = 257 Score = 74.5 bits (175), Expect = 2e-12 Identities = 59/210 (28%), Positives = 100/210 (47%), Gaps = 3/210 (1%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV + G TGIG ++ L D G ++ E+ + E+ + G +T SDV Sbjct: 10 KVAVVVGGTTGIGRAISFGLADAGADVVSTARREEQVNAAAD-EIERR-GRQTLRVCSDV 67 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAIEI 361 T+ + NAV+ + +D+++N A + + E N + +T L+A ++ Sbjct: 68 TSRASIQSLCNAVLAKFQKVDILVNCAGTTKRTPTLTVSEDEWNKILDTNLTGALRACQV 127 Query: 362 MGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538 GKH +G G +IN++S+++ H + Y A+K+A+L + + +SK GV V Sbjct: 128 FGKHMIERGYGRIINIASLSSFVALHEVAAYSASKAALLSLTRSLA--VEWSKKGVTVNA 185 Query: 539 VCFGATDTALLTDEKLGTFDKYLEFFMLGP 628 + G TAL T E L + EF M P Sbjct: 186 IAPGVFRTALNT-ELLDNTPRGQEFLMRTP 214 >UniRef50_Q0VL04 Cluster: Oxidoreductase, putative; n=1; Alcanivorax borkumensis SK2|Rep: Oxidoreductase, putative - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 581 Score = 74.5 bits (175), Expect = 2e-12 Identities = 56/194 (28%), Positives = 97/194 (50%), Gaps = 7/194 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K V ITGA +GIG G + DI E + + ++ G + + DV Sbjct: 315 KRVIITGAGSGIGRETALAFARRGAL-VVCTDINSEEAAATARTITAE-GGEALSRKCDV 372 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALIT-STL 346 +N + V +E G D+V+NNA +L++ S+ +++ + VN+ +I S L Sbjct: 373 SNTRSMEALATWVEKELGAPDIVVNNAGIGLSGSLLDTSVKDWQQVLGVNLWGVIHGSRL 432 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 A +++ + G+ G ++N++S AA S ++P Y +KSAVL FS C+ R E + + Sbjct: 433 FARQMIDQ---GRAGHIVNIASAAAFMPSRMLPAYATSKSAVLMFSECL-RAE-MDEHNI 487 Query: 527 RVLTVCFGATDTAL 568 V +C G +T + Sbjct: 488 GVSAICPGIINTPI 501 >UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chain dehydrogenase/reductase family; n=1; Photobacterium profundum|Rep: Hypothetical oxidoreductase, short-chain dehydrogenase/reductase family - Photobacterium profundum (Photobacterium sp. (strain SS9)) Length = 255 Score = 74.1 bits (174), Expect = 3e-12 Identities = 54/194 (27%), Positives = 89/194 (45%), Gaps = 7/194 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV I+G +GIGE+ R+ +G + ++ E G+ L ELN++Y T F ++D+ Sbjct: 10 KVALISGITSGIGEATARLFSQQGAS-LVLVARNENKGQMLAEELNAQY--PTLFIKADI 66 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 346 T + + E GGID NNA + S I+ + I N+ Sbjct: 67 TQANQVDQVFEQTMAEFGGIDCAFNNAGIDGSKQPISETSDEIWNQIINTNLNGTWNMLN 126 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 + + IM K GT++N++S+ ++ Y ++ AVL + ++K GV Sbjct: 127 RQLSIMSKQG---HGTIVNMASICSVLARPNRAAYNTSRHAVLGLTRSAA--VEYAKQGV 181 Query: 527 RVLTVCFGATDTAL 568 RV V GA DT + Sbjct: 182 RVNAVAPGAIDTPI 195 >UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rhodopseudomonas palustris BisB5|Rep: Short-chain dehydrogenase/reductase SDR - Rhodopseudomonas palustris (strain BisB5) Length = 263 Score = 74.1 bits (174), Expect = 3e-12 Identities = 52/195 (26%), Positives = 89/195 (45%), Gaps = 7/195 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 +VV +TG A+GIG + +G + + DI + G VE + G++ ++ R+DV Sbjct: 21 RVVLVTGGASGIGRAAALAWARQGCS-VLVADIDDRGGAET-VEAIERLGSRARYQRNDV 78 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 346 T+E ++ V G +DV NNA + S I ++ I VN+ + S Sbjct: 79 TDERECASLVEQAVLHFGRLDVAFNNAGITGPSAYIANYPGADWRHVINVNLLGIFNSMQ 138 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 + + S G G ++N +SV L Y A K V+ + C + ++G+ Sbjct: 139 PQLRLF--ESQG-AGVIVNTASVIGLRGVAGGSAYAAAKHGVIGLTKCAAL--EYGRSGI 193 Query: 527 RVLTVCFGATDTALL 571 R+ VC G +T L+ Sbjct: 194 RINAVCPGYIETPLV 208 >UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain dehydrogenase/reductase SDR precursor - Acidobacteria bacterium (strain Ellin345) Length = 271 Score = 74.1 bits (174), Expect = 3e-12 Identities = 55/192 (28%), Positives = 90/192 (46%), Gaps = 4/192 (2%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TG A GIGE+ R + G +AILD E+AG + + +G + KF+R DV Sbjct: 8 KVAVVTGGAMGIGEACARKIALAGAS-VAILDPNEDAGTKTAAAIRA-HGGECKFFRCDV 65 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 367 + + + V+ + ID++++NA + G E + +I LK ++ Sbjct: 66 SKSKDVEQAVGDVITKHSQIDILVSNAGI--QYYGDVITTPEDDWDRVIGVNLKGCFLIS 123 Query: 368 K----HSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535 K H GG ++ + SV + T Y +K AVL + + ++ G+RV Sbjct: 124 KFCVPHMISNGGAIVVLGSVQSFTAIQNSAAYVTSKHAVLGLARAMAL--DYAHKGIRVN 181 Query: 536 TVCFGATDTALL 571 VC G DT +L Sbjct: 182 CVCPGTIDTPML 193 >UniRef50_A6UZF9 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=16; Pseudomonas|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Pseudomonas aeruginosa PA7 Length = 266 Score = 74.1 bits (174), Expect = 3e-12 Identities = 55/197 (27%), Positives = 97/197 (49%), Gaps = 7/197 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 + ITGA++GIG ++ L G + + ++ +A +S+ EL ++G + F D+ Sbjct: 3 RYALITGASSGIGLALAEALARRG-RALILVARQRDALESIAYELAQRFGVEVLFRTCDL 61 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 349 G+L+ + Q + ID+++NNA + ++ ++ IE+N+ AL + Sbjct: 62 AEPLQLSGLLHELEQGERQIDLLVNNAGIGSAGPFVDQEWAREQELIELNILALA----R 117 Query: 350 AIEIMGKHSGGKGG-TVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 +G +GG ++NV+SVAA M Y+A+K+ VL FS G E V Sbjct: 118 LCHALGTRMAAQGGGQILNVASVAAFQPGAWMSNYYASKAYVLHFSE--GLREELKARAV 175 Query: 527 RVLTVCFGATDTALLTD 577 +V +C G T TA + Sbjct: 176 KVSVLCPGPTRTAFFRE 192 >UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1; Flavobacteriales bacterium HTCC2170|Rep: Probable glucose 1-dehydrogenase - Flavobacteriales bacterium HTCC2170 Length = 268 Score = 74.1 bits (174), Expect = 3e-12 Identities = 53/198 (26%), Positives = 93/198 (46%), Gaps = 5/198 (2%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K K V +TG + GIG + R L G + + E++ + L E+++ YG +T + Sbjct: 7 KGKRVLVTGGSRGIGAEICRKLAACGAEVFINYNSNEQSAQDLANEISNSYGVRTGIACA 66 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361 DV+ E + + GGID+++NNA +SI +E +I LK + Sbjct: 67 DVSKAEQVKQMFLKMDGVMGGIDILVNNAG--TESIHHVLDLVEEEWDRVINVNLKGPFL 124 Query: 362 MGKHSGGK-----GGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 K +G + GG +IN+SS+ + + Y + K+ + S C+ ++ + Sbjct: 125 CSKEAGDRMEKNGGGVIINISSIHDVVPRKGLIHYCSAKAGLKMLSKCLSL--ELAENNI 182 Query: 527 RVLTVCFGATDTALLTDE 580 RV++V GA T + DE Sbjct: 183 RVVSVAPGAISTEMNRDE 200 >UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8; Bacteria|Rep: Short-chain alcohol dehydrogenase - Burkholderia dolosa AUO158 Length = 284 Score = 74.1 bits (174), Expect = 3e-12 Identities = 57/195 (29%), Positives = 100/195 (51%), Gaps = 7/195 (3%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 +KVV ITGA++GIGE+ ++L +G +A+ + + + E+ +K G + ++ D Sbjct: 44 NKVVVITGASSGIGEATAKLLASKGAT-VALAARRLDKLQRVAAEIVAK-GGQVSVHQVD 101 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDS-IGIYK-----KAIEVNVTALITSTL 346 VT++E ++N VV + G +DV++NNA LM + + + K + I++N+ L+ Sbjct: 102 VTDQEQVNRLINDVVSQHGRLDVMVNNAGLMAIAPLSLRKTDEWDRMIDINIKGLLYGVA 161 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAAL-TQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 A+ + K + G +N++SV L S +Y TK AV S + H Sbjct: 162 AALPVFEKQ---QSGHFVNIASVVGLKVFSPGGTVYSGTKFAVRAISEGL---RHEVGGN 215 Query: 524 VRVLTVCFGATDTAL 568 +R + GA DT L Sbjct: 216 IRTTVISPGAIDTEL 230 >UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=1; marine gamma proteobacterium HTCC2143|Rep: Short-chain dehydrogenase/reductase - marine gamma proteobacterium HTCC2143 Length = 264 Score = 74.1 bits (174), Expect = 3e-12 Identities = 57/193 (29%), Positives = 98/193 (50%), Gaps = 6/193 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV ITG +GIGE+ I + EG + + +EE G+++ ++ G+K + ++DV Sbjct: 8 KVAIITGGTSGIGEATADIYIKEGAT-VVLTGRSEEKGQAIA----NRLGDKAHYIKADV 62 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNA----ALMNDSI--GIYKKAIEVNVTALITSTLK 349 + EE ++ V+ G +DV+ NNA DSI G +++ +++++ Sbjct: 63 SKEEDIANTISETVERFGKLDVLFNNAGGPVGGTIDSIAPGDINYGVDLLLSSVVLGIRY 122 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 AIE M K +G GG +IN +S+AA+ +Y A K+AV ++ G G+R Sbjct: 123 AIEPM-KANG--GGVIINNTSIAAIRYRQGNLLYSALKAAVTHYTKLAG--VELGPLGIR 177 Query: 530 VLTVCFGATDTAL 568 V + GA T + Sbjct: 178 VNCISPGAIATPI 190 >UniRef50_Q54D03 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 292 Score = 74.1 bits (174), Expect = 3e-12 Identities = 54/197 (27%), Positives = 93/197 (47%), Gaps = 6/197 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV F+TG A+GIG +V + EG K +AI+D+ + + ELN ++ T DV Sbjct: 36 KVCFVTGGASGIGLGIVERFVKEGGK-VAIVDLDKTKADNASKELNQRFPGSTISVECDV 94 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 349 +NEE + V+ GG+DV+++NA L + + ++K + V++ T Sbjct: 95 SNEEQVSKGIKDTVERFGGLDVIVSNAGLQHIETLETVELATWRKMMAVHLDGAFLCTKY 154 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 A++ K +GGT++ + SV + S Y K + C G +K +R Sbjct: 155 AMQEF-KKDIKRGGTILYMGSVHSKYASEYKIPYVTAKHGLEGL--CRGVAREGAKHNIR 211 Query: 530 VLTVCFGATDTALLTDE 580 +C G T L+ ++ Sbjct: 212 ANLICPGFVLTPLVKNQ 228 >UniRef50_UPI00015B572E Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 240 Score = 73.7 bits (173), Expect = 3e-12 Identities = 45/152 (29%), Positives = 78/152 (51%), Gaps = 4/152 (2%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQ---VELNSKYGN-KTKF 172 +KV +T GIG S + L +++A+LD+ + + L ++G K + Sbjct: 5 NKVAIVTDGLGGIGFSTYLLRLK--AQYVAVLDLPQNNSPHVVDGLKTLEEEFGKGKFGY 62 Query: 173 YRSDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 352 Y +V N E F + VV+ +G +D+++ NAA+ D+ I+VN+ +I TL A Sbjct: 63 YHVNVANAESFAAVYAKVVEHKGYVDILVYNAAVAKDTE--IDLTIDVNLKGVIKGTLHA 120 Query: 353 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPI 448 +E MG H KGG V+N++S L + + + Sbjct: 121 VEQMGVHKNQKGGVVVNIASFLGLEHNKFLGV 152 >UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n=2; Bacillaceae|Rep: 2O-beta-hydroxysteroid dehydrogenase - Oceanobacillus iheyensis Length = 244 Score = 73.7 bits (173), Expect = 3e-12 Identities = 63/217 (29%), Positives = 107/217 (49%), Gaps = 6/217 (2%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 ++KV ITG A G+G S VR+ EG K + D+ EE G +L EL G KF + Sbjct: 5 ENKVAIITGGARGMGASHVRLFAKEGAK-VVFTDLNEEGGLALANEL----GENVKFVKQ 59 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 343 DVTN + + +++ + G ++V++NNA LM + Y+K I++N ++ Sbjct: 60 DVTNADDWETVISETEEAFGPVNVLVNNAGISLSIPLMEMTEEQYRKIIDINQVSVFLG- 118 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 +KA+ + +G G+++N+SS+ + V Y +K AV + G Sbjct: 119 MKAVVPSMQKAG--SGSIVNISSMNGIVAGAVG--YTDSKFAVRGATKAAA--VQLGGLG 172 Query: 524 VRVLTVCFGATDTALLTDEKLGTFDKYLEFFMLGPTK 634 +RV +V G +T ++T K ++ EF P+K Sbjct: 173 IRVNSVHPGVIETPMVT--KGDAVEQIKEFAKQIPSK 207 >UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacillus thuringiensis Length = 247 Score = 73.7 bits (173), Expect = 3e-12 Identities = 50/196 (25%), Positives = 98/196 (50%), Gaps = 6/196 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TG A GIG+++ L EG K + + ++EA ++L EL K G+ ++DV Sbjct: 7 KVAIVTGGAKGIGKAITVALAQEGAKVVINYNSSKEAAENLVNEL-GKEGHDVYAVQADV 65 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 349 + E ++ V G +D+++NNA + D + +++ I+VN++++ +T Sbjct: 66 SKVEDANRLVEEAVNHFGKVDILVNNAGITRDRTFKKLNREDWERVIDVNLSSVFNTTSA 125 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 + + + + G +I++SS+ Y A K+ +L F+ + +KT V Sbjct: 126 VLPYI---TEAEEGRIISISSIIGQAGGFGQTNYSAAKAGMLGFTKSLAL--ELAKTNVT 180 Query: 530 VLTVCFGATDTALLTD 577 V +C G DT ++ + Sbjct: 181 VNAICPGFIDTEMVAE 196 >UniRef50_Q12G63 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=6; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 249 Score = 73.7 bits (173), Expect = 3e-12 Identities = 63/213 (29%), Positives = 98/213 (46%), Gaps = 6/213 (2%) Frame = +2 Query: 14 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTN 193 V +TGA TGIG + +G ++ + EEAG+SL EL + G K +F ++DV N Sbjct: 6 VLVTGALTGIGRATAIAFAKQGA-NVVVSGRREEAGQSLAAELRT-LGAKAEFIKADVAN 63 Query: 194 EEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKH 373 E ++ V G +D+ INNA ++G + NV A ++ + + KH Sbjct: 64 EAEVRSLVEKAVSLFGQLDIAINNAG-TEGALGPITEQSTENVHATFSTNVLGTLLSMKH 122 Query: 374 S----GGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLT 538 +G G+++N+SS+A +Y A+K AV + + GVRV Sbjct: 123 EIRAMQAQGHGSIVNLSSIAGKVGMAGASVYVASKHAVEGLTKSAAL--EGAAFGVRVNA 180 Query: 539 VCFGATDTALLTDEKLGTFDKYLEFFMLG-PTK 634 V G T +L D +G + FM G P K Sbjct: 181 VAPGPVQTDML-DRFVGRDESVKAGFMAGVPAK 212 >UniRef50_A6CTS3 Cluster: Putative uncharacterized protein; n=1; Bacillus sp. SG-1|Rep: Putative uncharacterized protein - Bacillus sp. SG-1 Length = 260 Score = 73.7 bits (173), Expect = 3e-12 Identities = 61/202 (30%), Positives = 95/202 (47%), Gaps = 7/202 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K+KVV ITGA++G+G + + + +E+ +L EL K+G K Sbjct: 2 KNKVVVITGASSGLGVEFAKQFAGRSYD-LVLTARSEDKLNNLAKELEGKHGIKAHVIPI 60 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAAL----MNDSIGIYKKA--IEVNVTALITST 343 D++ + VV +++INNA + I K+ IEVN+TAL T Sbjct: 61 DLSQHGSAKTLHEKVVSLGLTTEILINNAGFGLFGEFEDTDIQKEVDMIEVNITALTELT 120 Query: 344 LKAIEIMGKHSG-GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 + GK G G ++NV+SVAA +M +Y+ATK+ VL S + + Sbjct: 121 ----KYFGKEMVVGNTGKILNVASVAAFQPGPLMAVYYATKAYVLSLSEALS--NEWKDK 174 Query: 521 GVRVLTVCFGATDTALLTDEKL 586 GV+V +C GAT+T +L Sbjct: 175 GVKVSVLCPGATETGFSNSAEL 196 >UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like protein; n=1; Reinekea sp. MED297|Rep: Short-chain alcohol dehydrogenase-like protein - Reinekea sp. MED297 Length = 672 Score = 73.7 bits (173), Expect = 3e-12 Identities = 51/169 (30%), Positives = 90/169 (53%), Gaps = 8/169 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KVV ITG ++GIG++ L G I AE+ ++ +++ S G +++D+ Sbjct: 385 KVVLITGGSSGIGKATAMRLSKAGATVIICARDAEKLRRA-HLDIESTGGTVVS-HQADI 442 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNA------ALMN--DSIGIYKKAIEVNVTALITST 343 T + + + +E G+D++INNA ++M D + +++ IE+N A + T Sbjct: 443 TQPDDVDRLFGMIEREFAGLDILINNAGHSIRRSVMQSLDRLHDFQRTIELNYLASVAIT 502 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNC 490 LKA+ +M + + G VIN+SS+ L+ S Y A+K+A+ FS C Sbjct: 503 LKALPMMDRR---REGHVINISSIGVLSNSPRFSAYVASKAALEAFSRC 548 >UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Short-chain dehydrogenase/reductase SDR - Candidatus Nitrosopumilus maritimus SCM1 Length = 253 Score = 73.7 bits (173), Expect = 3e-12 Identities = 49/173 (28%), Positives = 95/173 (54%), Gaps = 10/173 (5%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 DKV +TGA++ IG+ + + ++EG K I I E ++ + E+ ++ + T D Sbjct: 5 DKVAIVTGASSDIGKGIAKKFVEEGAKVILIARNLEGL-ENTRKEIGNE--DSTAAMTCD 61 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALITST 343 + +E L ++N ++ G ID+++NNA +ND I + +K I VN+ + T Sbjct: 62 LVDESQTLQVVNQIMDTYGKIDILVNNAGAINDPIHFHEMQNSEIQKLINVNLLGVFNMT 121 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVA---ALTQSHVMPIYFATKSAVLQFSNCV 493 KA ++ K + K G+++N+ S++ A+ + H + +Y ATK+A+ F+ + Sbjct: 122 -KA--VLTKMADVKSGSIVNIGSISSERAIPRVH-LAVYSATKAAIPMFTKSI 170 >UniRef50_Q13H99 Cluster: Putative short-chain dehydrogenase/reductase; n=3; Proteobacteria|Rep: Putative short-chain dehydrogenase/reductase - Burkholderia xenovorans (strain LB400) Length = 274 Score = 73.3 bits (172), Expect = 4e-12 Identities = 60/223 (26%), Positives = 107/223 (47%), Gaps = 14/223 (6%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 ++KV +TGA G+G + R L G + +A++DI EA ++ ++ G + R+ Sbjct: 11 ENKVAIVTGAGAGLGAACARALAQHGAR-VAVVDINGEAAAAVAADI----GERAMSVRT 65 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMND------------SIGIYKKAIEVNVT 325 DV++E +++AV++ G ID++ NNAA+++D S+ ++ +A+ VN+ Sbjct: 66 DVSSEAQVKAMVSAVLEHFGRIDILHNNAAVLDDAQRAGDRDVINMSVEVWDRAMAVNLR 125 Query: 326 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPE 505 + AI M + G GG++I+ SS M Y A+K+ + S V Sbjct: 126 GAMLCCKHAIPAMLR---GGGGSIIHSSSGFGAQGDFTMSAYAASKAGLAMLSKSVA--A 180 Query: 506 HFSKTGVRVLTVCFG--ATDTALLTDEKLGTFDKYLEFFMLGP 628 + K +R T+ G D L D K D +L ++ P Sbjct: 181 QYGKERIRSNTIQIGLVVADHPLPEDIKGVILDGHLTPYLGDP 223 >UniRef50_A7IMM1 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Xanthobacter autotrophicus Py2|Rep: Short-chain dehydrogenase/reductase SDR precursor - Xanthobacter sp. (strain Py2) Length = 261 Score = 73.3 bits (172), Expect = 4e-12 Identities = 57/201 (28%), Positives = 97/201 (48%), Gaps = 8/201 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 KDK + ITGAA GIG ++ + L +G + I + D++E A +++ E+ + G Sbjct: 5 KDKSIVITGAAGGIGAAIAKALAADGAR-ITVADLSEPAARAVAGEITAA-GGTAIAVAV 62 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 343 DV +L+ V G +DV+ NNA + ++ + ++ +VN ++ Sbjct: 63 DVRQRAQVRALLDEAVAAHGRLDVLFNNAGVAQTRPFLDITEDDWRFVTDVNALGVLIGM 122 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 +AI+ K GG GG ++N +S+AA + Y A+K AV+ + R F K Sbjct: 123 QEAIKTF-KRQGG-GGKIVNTASIAAKQGYEPLAHYCASKFAVVALTQAAARA--FGKDQ 178 Query: 524 VRVLTVCFG--ATDTALLTDE 580 + V C G ATD + D+ Sbjct: 179 ITVNAFCPGVVATDMWKIIDK 199 >UniRef50_A6BFV0 Cluster: Putative uncharacterized protein; n=1; Dorea longicatena DSM 13814|Rep: Putative uncharacterized protein - Dorea longicatena DSM 13814 Length = 244 Score = 73.3 bits (172), Expect = 4e-12 Identities = 56/221 (25%), Positives = 101/221 (45%), Gaps = 9/221 (4%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 + K +FITGA+ GIG+S+ + G + + K L+ + KY Sbjct: 2 EQKTIFITGASRGIGKSIALLFASRGYHTFLNCSSSVDELKKLRAYITEKYHTPCTLVPG 61 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAA-----LMNDSIG-IYKKAIEVNVTALITST 343 +V N +H I N + QE +DV++NNA L+ D + + I+ N++++ Sbjct: 62 NVGNPDHVRAIYNKIYQECTHLDVLVNNAGISYINLLTDMTDEDWNRIIQTNLSSVFYCC 121 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 +AI M GK +IN+SS+ + + Y A+KS + F+ + + + + Sbjct: 122 RQAIPPMVSKRSGK---IINISSMWGTSGASCEVAYSASKSGINGFTKALAK--ELAPSN 176 Query: 524 VRVLTVCFGATDTAL---LTDEKLGTFDKYLEFFMLGPTKE 637 V+V + G DT++ LT E+ ++ + G KE Sbjct: 177 VQVNAIACGVIDTSMNDQLTSEERKALEEEIPAGRYGTPKE 217 >UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Arthrobacter aurescens TC1|Rep: Putative 3-oxoacyl-[acyl-carrier protein] reductase - Arthrobacter aurescens (strain TC1) Length = 261 Score = 73.3 bits (172), Expect = 4e-12 Identities = 55/194 (28%), Positives = 96/194 (49%), Gaps = 6/194 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K V +TGA +G+G +V + L EG I + D++E++ + + NS + +DV Sbjct: 9 KTVMVTGAGSGLGAAVFKRFLLEGANVIGV-DLSEDSMARFR-DRNSVLSGQITLKVADV 66 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 349 + + I+N V+E G +DV++NNA + S +++ ++VNV L +T Sbjct: 67 GDPDAIEAIINESVEELGALDVLVNNAGIAPTGPAATTSNELWRSVMKVNVDGLFYATRA 126 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 A+ H G ++N +SV+ + + Y A+K AV+ F+ V +++ GVR Sbjct: 127 AL----PHLIQSQGNIVNTASVSGIGADYNYAAYDASKGAVINFTRSVA--VDYAQRGVR 180 Query: 530 VLTVCFGATDTALL 571 V G T LL Sbjct: 181 CNAVAPGPVLTPLL 194 >UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Rep: Short chain dehydrogenase - Mycobacterium avium (strain 104) Length = 594 Score = 73.3 bits (172), Expect = 4e-12 Identities = 54/193 (27%), Positives = 91/193 (47%), Gaps = 6/193 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 + ++ +TGA GIG + L +G + + I+D + A + G Y+ Sbjct: 324 RGRLALVTGAGAGIGRATAVELARQGARKVVIVD-RDRAAADQTADAVRAAGAGAAVYQV 382 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361 DV++E + V E G +D+++NNA + G + + N A++ ++ + Sbjct: 383 DVSDEAAMNDLAAQVRNEHGVVDILVNNAGI--GMAGRFLETSPANWDAIMGVNVRGVIW 440 Query: 362 MGKHSG------GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 + G G+GGT+INV+S AA S M Y TK+AVL S + R + F+ G Sbjct: 441 GSRAFGAQMVERGQGGTIINVASAAAYLPSKSMVAYGTTKAAVLALSESL-RAD-FADEG 498 Query: 524 VRVLTVCFGATDT 562 + V VC G +T Sbjct: 499 ITVTAVCPGFVNT 511 >UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34; Proteobacteria|Rep: Acetoacetyl-CoA reductase - Acinetobacter sp. (strain RA3849) Length = 248 Score = 73.3 bits (172), Expect = 4e-12 Identities = 51/197 (25%), Positives = 91/197 (46%), Gaps = 6/197 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 + KV +TGA GIG + R L+ G K IA + EE + ++ + +F + Sbjct: 3 EQKVALVTGALGGIGSEICRQLVTAGYKIIATVVPREEDREKQWLQSEGFQDSDVRFVLT 62 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITST 343 D+ N E + + +G +DV++NNA + D S + + I+ N+ L T T Sbjct: 63 DLNNHEAATAAIQEAIAAEGRVDVLVNNAGITRDATFKKMSYEQWSQVIDTNLKTLFTVT 122 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 + K K G ++N+SSV L Y A+K+ ++ F+ + + +++ Sbjct: 123 Q---PVFNKMLEQKSGRIVNISSVNGLKGQFGQANYSASKAGIIGFTKALA--QEGARSN 177 Query: 524 VRVLTVCFGATDTALLT 574 + V V G T T ++T Sbjct: 178 ICVNVVAPGYTATPMVT 194 >UniRef50_P50197 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=8; root|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Pseudomonas paucimobilis (Sphingomonas paucimobilis) Length = 250 Score = 73.3 bits (172), Expect = 4e-12 Identities = 51/195 (26%), Positives = 94/195 (48%), Gaps = 7/195 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K + +TG +GIG + V +L+ G ++ + DI +EAG+++ + G K ++R D+ Sbjct: 7 KTIIVTGGGSGIGRATVELLVASGA-NVPVADINDEAGEAVV----ATSGGKAAYFRCDI 61 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 346 EE ++ + GG+D NNAA L S+ +++++++NVT T Sbjct: 62 AQEEDVKALVAQTLAAFGGLDGSFNNAAIPQAGLPLAEVSLERFRQSMDINVTG--TFLC 119 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 +I+ G G+++N +S A + + Y K AV+ + + K G+ Sbjct: 120 MKYQILAMIERGTKGSIVNTASAAGVVGVPMHGEYVGAKHAVVGLTRVAA--ADYGKHGI 177 Query: 527 RVLTVCFGATDTALL 571 RV + GA T +L Sbjct: 178 RVNALVPGAVRTPML 192 >UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oceanobacillus iheyensis|Rep: Hypothetical conserved protein - Oceanobacillus iheyensis Length = 254 Score = 72.9 bits (171), Expect = 6e-12 Identities = 60/197 (30%), Positives = 93/197 (47%), Gaps = 7/197 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KVV ITG A GIG++ ++LLD G K +A++DI E++ + L+ + ++ +V Sbjct: 4 KVVLITGGAGGIGQATAKLLLDYGAK-VALVDINEDSLVKAKESLHVE-DDRVFTITGNV 61 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 346 T EE + V G IDV NNA + I ++K + +NVT + Sbjct: 62 TVEEDVENYVKQTVDRFGKIDVFFNNAGVNGPVSPITELDQATFEKIMSINVTGVFLGLK 121 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 ++ M K G+++N +S AA S M Y A+K AV + + G+ Sbjct: 122 HVMKQMKKQG---YGSIVNTASNAAYIGSAGMVSYIASKHAVAGITKTAAL--EVASDGI 176 Query: 527 RVLTVCFGATDTALLTD 577 RV V A DT +L D Sbjct: 177 RVNAVAPAAIDTQMLAD 193 >UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=6; Desulfuromonadales|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Geobacter sulfurreducens Length = 246 Score = 72.9 bits (171), Expect = 6e-12 Identities = 57/215 (26%), Positives = 98/215 (45%), Gaps = 5/215 (2%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 KD +V +TG GIG ++ +G A +EA ++L+ E G+ R+ Sbjct: 4 KDSIVVVTGGTRGIGRAISLHFARQGALVTAAYRADDEAARALEAEAAGLPGS-IAVIRA 62 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361 DV E + +++A E G + V++NNA ++ D G E + A++ + L + Sbjct: 63 DVGTAEGAMAVIDAASGESGTLHVLVNNAGIIRD--GYLAMMAEDDWDAVMRANLSPLFH 120 Query: 362 -----MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 + K + G +IN+SSV+A + Y ATK A + F+ + R G+ Sbjct: 121 CCKWGVRKMLARRRGAIINLSSVSAFAGTAGQTNYAATKGAAVSFTKSLAR--EVGPLGI 178 Query: 527 RVLTVCFGATDTALLTDEKLGTFDKYLEFFMLGPT 631 RV V G +T ++ K D+ + +LG T Sbjct: 179 RVNAVAPGLIETEMIAGMKREMVDRIVGSSILGRT 213 >UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase, putative; n=26; Gammaproteobacteria|Rep: 3-oxoacyl-(Acyl carrier protein) reductase, putative - Idiomarina loihiensis Length = 254 Score = 72.9 bits (171), Expect = 6e-12 Identities = 62/222 (27%), Positives = 98/222 (44%), Gaps = 15/222 (6%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 KD V+ ITG A G+G ++ +G K +A++DI + Q + K Y Sbjct: 4 KDSVIVITGGAQGLGLAMAEDFARQGAK-LALIDINGDVLGEAQEQCEKLGAAKVVGYEV 62 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI---------------YKKAIEV 316 D+T+EE + + QE GIDV++NNA L+ D + I ++ ++V Sbjct: 63 DITDEESVETVFEQIQQEFDGIDVLVNNAGLLRDGLLIKFKDGELKQKMPLQQFQSVLDV 122 Query: 317 NVTALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVG 496 N+T +A M K GK G +IN+SSVA + Y ATK+ V+ + V Sbjct: 123 NLTGTFLCGREAAAQMVK--AGKKGVIINISSVAR-AGNMGQTNYSATKAGVVAMT--VT 177 Query: 497 RPEHFSKTGVRVLTVCFGATDTALLTDEKLGTFDKYLEFFML 622 + G+R + G +T + K D+ L L Sbjct: 178 WARELGRYGIRCGAIAPGFIETPMTAQMKPEAVDRALSMVPL 219 >UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Strongly similar to 3-oxoacyl-[acyl-carrier protein] reductase - Candidatus Kuenenia stuttgartiensis Length = 239 Score = 72.9 bits (171), Expect = 6e-12 Identities = 53/210 (25%), Positives = 104/210 (49%), Gaps = 7/210 (3%) Frame = +2 Query: 14 VFITGAATGIGESVVRILLDEG----VKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 + +TG + GIG+++ ++ + EG V H +D E+ L+ E +S G+ + ++ Sbjct: 1 MLVTGGSKGIGKAICKVFIGEGDHVIVNHCKPIDDIEK----LREEFSSPQGSFS-IEKA 55 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAI 355 DVT+ +++ +V++ G IDV+INNA ++ D + A + N + +T Sbjct: 56 DVTDYAQIKQMVDNIVKKHGKIDVLINNAGIIKDGYIMLMSAKDWNDVINVNLTGVFNCT 115 Query: 356 EIMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532 + + +H G + GT+IN++S++ +T Y A K V+ F+ + + + +RV Sbjct: 116 KAVSEHMIGQRSGTIINIASLSGITGLPGQTNYSAAKGGVIAFTMALSK--ELAPFCIRV 173 Query: 533 LTVCFGATDTALLTDEKLGTFDKYLEFFML 622 TV G +T ++ + Y E L Sbjct: 174 NTVAPGVIETDIIDSLDKNKRNSYKEHIPL 203 >UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Parvibaculum lavamentivorans DS-1|Rep: Short-chain dehydrogenase/reductase SDR - Parvibaculum lavamentivorans DS-1 Length = 287 Score = 72.9 bits (171), Expect = 6e-12 Identities = 54/193 (27%), Positives = 94/193 (48%), Gaps = 6/193 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV ITG +GIG V + L EG K +A D+ + G++++ EL G + R++V Sbjct: 7 KVAIITGGTSGIGRGTVDLFLKEGAKVVAA-DLQDHKGEAMEREL----GENFSYCRANV 61 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN-----VTALITSTLKA 352 +E+ +++ V++ G +D++ NNA +G + I++N V L+ + Sbjct: 62 AHEDEVKNLVDHTVKKFGKLDILFNNAGY--GGVGGELQEIDMNGFDETVGVLLKGVVLG 119 Query: 353 IEIMGKH-SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 + H K G++I+ +SVA L + +Y A K+AV FS C + VR Sbjct: 120 YKYAVPHMKAQKSGSIISTASVAGLQAGYGPLVYSACKAAVHHFSRCAAL--ELAPHFVR 177 Query: 530 VLTVCFGATDTAL 568 +C G T++ Sbjct: 178 SNAICPGGIATSI 190 >UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4; Legionella pneumophila|Rep: Acetyoacetyl CoA reductase - Legionella pneumophila (strain Corby) Length = 248 Score = 72.9 bits (171), Expect = 6e-12 Identities = 49/172 (28%), Positives = 84/172 (48%), Gaps = 7/172 (4%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE-EAGKSLQVELNSKYGNKTKFYRS 181 + VV ITG IG +V + LD KH+ LD+ + G+ +L ++ F Sbjct: 4 NNVVLITGGTGDIGTAVAK-QLDSTFKHVIALDLVSYDEGEVWLHDLKTQGYKNINFRHM 62 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 343 DVT+ E ++ +++E GGIDV+INNA + D++ + + + VN+ + T Sbjct: 63 DVTDYEQCAEVIGLIIEEFGGIDVLINNAGITRDAVFTKMTKRQWDEVLRVNLDGMFNVT 122 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGR 499 + +E M G+ ++NVSSV A Y A+K+ V F+ + + Sbjct: 123 KQVVESMKVQESGR---IVNVSSVNAQKGQFSQANYAASKAGVYGFTKSLAQ 171 >UniRef50_A1WKP5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Verminephrobacter eiseniae EF01-2|Rep: Short-chain dehydrogenase/reductase SDR - Verminephrobacter eiseniae (strain EF01-2) Length = 265 Score = 72.9 bits (171), Expect = 6e-12 Identities = 55/197 (27%), Positives = 94/197 (47%), Gaps = 6/197 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV ITGA +GIG + + EG + I + D+ E G++ V + G + F ++DV Sbjct: 16 KVALITGAGSGIGRATALLFATEGAQ-IVVCDLDPEGGQAT-VRAIEQAGAQALFVQADV 73 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 349 + ++ +DV+ NNA + ++ S + + VNV ++ + + Sbjct: 74 AQAADCARAVQQTLRHFARLDVLFNNAGITCRANVVDTSEADWDAVMAVNVKSIFLMSRQ 133 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 A+ +M + GG ++IN S L Y A K AV+ + + +H + +R Sbjct: 134 AVPVMAEQGGG---SIINAGSGWGLVGGRDAVSYCAAKGAVVNMTRAMAL-DHGPQR-IR 188 Query: 530 VLTVCFGATDTALLTDE 580 V +VC G TDTA+L DE Sbjct: 189 VNSVCPGDTDTAMLRDE 205 >UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative - Rhizobium meliloti (Sinorhizobium meliloti) Length = 249 Score = 72.5 bits (170), Expect = 8e-12 Identities = 57/194 (29%), Positives = 99/194 (51%), Gaps = 7/194 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K+ +TGA++GIG + L + G K + I + + L+ ++ +K G + DV Sbjct: 7 KIALVTGASSGIGAATAAKLAEAGAK-VGIAARRTDKLEDLKKKIEAK-GGEALVIEMDV 64 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALM--ND----SIGIYKKAIEVNVTALITSTLK 349 + + +V G ID+++NNA LM +D + +++ ++VNV L+ +T Sbjct: 65 VDTTSVEAGVKKLVDAYGSIDILVNNAGLMPLSDIDQFKVDEWQRMVDVNVKGLLNTTAA 124 Query: 350 AI-EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 + +++ +HS G V N+SS+A + +Y ATK AV FS+ + R E K G+ Sbjct: 125 VLPQMIKQHS----GHVFNMSSIAGRKVFKGLSVYCATKHAVTAFSDGL-RMEVGQKHGI 179 Query: 527 RVLTVCFGATDTAL 568 RV + GA T L Sbjct: 180 RVTCIQPGAVATEL 193 >UniRef50_Q8FA17 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=3; Leptospira|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Leptospira interrogans Length = 247 Score = 72.5 bits (170), Expect = 8e-12 Identities = 50/189 (26%), Positives = 88/189 (46%), Gaps = 2/189 (1%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K+K V +TG+ GIG EG K+ I G S Q + G+ K + + Sbjct: 8 KNKTVLVTGSTRGIGRYFA-----EGFKNAGA--IVYGTGSS-QESIKKFDGSGIKGFAA 59 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAI 355 D+ + I+ ++V+E G +DV++NNA + ++ + K E+ + T +A Sbjct: 60 DIRQPDVMTPIIESIVKEHGRLDVLVNNAGIASNKPAAFLKEDEIESIIQTNFTGVFRAC 119 Query: 356 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535 K KGG +IN++S+ + + + +Y TK AV+ + + + +G RV Sbjct: 120 TAYYKIHKKKGGNIINIASILGMRGTKLASVYSGTKGAVINMTRALA--VEWIGSGYRVN 177 Query: 536 TVCFGATDT 562 +C G DT Sbjct: 178 AICPGFIDT 186 >UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Burkholderiaceae|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 252 Score = 72.5 bits (170), Expect = 8e-12 Identities = 51/182 (28%), Positives = 91/182 (50%), Gaps = 6/182 (3%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 +KV +TGAA+G+G + +L EG + + + DI E+AG++L E+ G+ F R D Sbjct: 6 NKVALVTGAASGVGRADALLLAAEGAR-VVLTDIDEDAGRALAREI----GDAALFVRHD 60 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 346 + +E + + + + G +DV++NNAA+ + S+ +++ + N Sbjct: 61 IADEAGWQHAIASTLDRFGRLDVLVNNAAICPVGSIEDTSLDTWRRVMRTNADGYFLGCK 120 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 AI M G+++ +SSVAAL +M Y +K AV + V H ++G Sbjct: 121 YAIGAM--KGNDTPGSIVMMSSVAALGGLPMMCAYTGSKGAVTALARSVA--VHCKRSGY 176 Query: 527 RV 532 R+ Sbjct: 177 RI 178 >UniRef50_Q2JG54 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=3; Frankia|Rep: Short-chain dehydrogenase/reductase SDR precursor - Frankia sp. (strain CcI3) Length = 291 Score = 72.5 bits (170), Expect = 8e-12 Identities = 56/195 (28%), Positives = 92/195 (47%), Gaps = 4/195 (2%) Frame = +2 Query: 20 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTNEE 199 ITGA++GIG + D G + + + +E + L ++YG + D+ +E Sbjct: 14 ITGASSGIGAAFAEAYADRGARLVLVAP-SEPRLWMVAERLGARYGTEAHVIAVDLADER 72 Query: 200 HFLGILNAVVQEQGGIDVVINNAALMN----DSIGIYKKAIEVNVTALITSTLKAIEIMG 367 + AV + +D+++NNA + + EV + + + + + G Sbjct: 73 GPDRLAEAVAEAGLEVDILVNNAGFGTRGPYHELSADRDHREVMLNVVAVERVAHLFLPG 132 Query: 368 KHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTVCF 547 + G+G TVINVSS + M +Y A+K+ VL FS +G + + GVRVL +C Sbjct: 133 MVARGRG-TVINVSSTSGFQAVPYMTVYGASKAFVLSFS--IGLWAEYRRRGVRVLALCP 189 Query: 548 GATDTALLTDEKLGT 592 G TDT E LGT Sbjct: 190 GPTDTEFF--EVLGT 202 >UniRef50_Q1IPJ3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain dehydrogenase/reductase SDR - Acidobacteria bacterium (strain Ellin345) Length = 261 Score = 72.5 bits (170), Expect = 8e-12 Identities = 59/196 (30%), Positives = 93/196 (47%), Gaps = 7/196 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 +D+VV ITG GIG ++ R + EG I+ +E + + G + Sbjct: 28 EDQVVLITGGNRGIGLAMARAVAKEGAS--VIITGRDEHTLHHAADQIKRDGGTVVSHVC 85 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITS 340 DV +E+ + A+ + IDV++NNA L S+ ++ IE N+T Sbjct: 86 DVRDEDSVDELFAAIHRHYSQIDVLVNNAGLAQRNAQVDHLSLEAWQACIETNLTGAFLC 145 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 T A+ +M G TV+N SVAA T M Y A+K+ +L F+N + E Sbjct: 146 TRAALPMMSP-----GATVVNNVSVAANTAFPGMAAYSASKAGLLAFTNTL--REELRPR 198 Query: 521 GVRVLTVCFGATDTAL 568 G+RV+++ GATDT + Sbjct: 199 GIRVISLVPGATDTEI 214 >UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase precursor; n=2; Clostridium difficile|Rep: Probable short chain dehydrogenase precursor - Clostridium difficile (strain 630) Length = 245 Score = 72.5 bits (170), Expect = 8e-12 Identities = 49/209 (23%), Positives = 99/209 (47%), Gaps = 6/209 (2%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K K V ITG A GIG+++ + EG + + +E K L LN K K +++ Sbjct: 2 KKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKELYTILNEK-NFSVKLFKA 60 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 343 +++N E +++ ++E GG+DV++NNA + D + + + +N+ + Sbjct: 61 NISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITDEDWDNMMNINLKGSFYCS 120 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 A++ M K G +IN+SS+ ++ + Y TK+ ++ + + + + Sbjct: 121 QVALKYM---ISEKKGNIINISSIWGISGASCEVHYSITKAGIIGMTKALAK--EVGPSN 175 Query: 524 VRVLTVCFGATDTALLTDEKLGTFDKYLE 610 +RV ++ G +T +L+ D +E Sbjct: 176 IRVNSIAPGVINTDMLSGYNEEDIDALVE 204 >UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Roseiflexus sp. RS-1 Length = 246 Score = 72.5 bits (170), Expect = 8e-12 Identities = 58/196 (29%), Positives = 92/196 (46%), Gaps = 5/196 (2%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K KV +TGA GIG++ EG H+A++DI AG V ++ + ++ Sbjct: 4 KGKVAIVTGAGHGIGKATAIAFAREGA-HVAVVDI-NMAGAEATVAEITRLDGRALAVQA 61 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361 DV+ ++ V+ G IDV++NNA + D+ + K E A+I LK + + Sbjct: 62 DVSQAASVESMVETVLAWGGRIDVLLNNAGITRDARLV--KMTEQQWDAVINVNLKGVWL 119 Query: 362 MGK----HSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 + H +G G++INVSS+ L + Y ATK V+ + R +GV Sbjct: 120 CARAVAPHMSAQGSGSIINVSSIVGLYGNFGQSNYAATKGGVIAMTKTWAR--ELGPSGV 177 Query: 527 RVLTVCFGATDTALLT 574 RV V G T ++T Sbjct: 178 RVNAVTPGFIATEMIT 193 >UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family protein; n=1; Algoriphagus sp. PR1|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family protein - Algoriphagus sp. PR1 Length = 265 Score = 72.5 bits (170), Expect = 8e-12 Identities = 54/209 (25%), Positives = 105/209 (50%), Gaps = 8/209 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV+ +TG+ TGIG+++ + ++ EG K + I + E+ G+ + EL + + K + D+ Sbjct: 6 KVIIVTGSTTGIGKAIAKKVVSEGAK-VIIHGLEEDLGQQVVSELGA---DNAKLHIEDI 61 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITSTLK 349 +NE +++ V+ G +D ++NNAA++ S + +EVN + T Sbjct: 62 SNEGAAQRLVDIAVKTWGKLDSIVNNAAIVAASTLFDTDKAFLNRILEVNTISPFLLTQA 121 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 AI + ++ G V+N+ S+ A + H + Y +K A++ + +G F + GVR Sbjct: 122 AISQLIQNK----GAVLNIGSINAYSGEHNLLAYSISKGALMTMTRNLG-DSLFRENGVR 176 Query: 530 VLTVCFG--ATDTALLTDEKLGTFDKYLE 610 V + G T+ + ++ G D + E Sbjct: 177 VNQINPGWVLTENEIARKKEHGLSDTWYE 205 >UniRef50_A2U319 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Polaribacter dokdonensis MED152|Rep: Short-chain dehydrogenase/reductase SDR - Polaribacter dokdonensis MED152 Length = 259 Score = 72.5 bits (170), Expect = 8e-12 Identities = 59/193 (30%), Positives = 95/193 (49%), Gaps = 8/193 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K ITGA++G+G+ +I G + I+ +++ + L+ +L K+G D+ Sbjct: 3 KTALITGASSGLGKEFAKIHAKNG-GDLVIVARSKDKLQKLKEKLEKKHGVHVSIIEKDL 61 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG-IYKKA-------IEVNVTALITST 343 T + N V + ID +INNA IG +++A I++N+ AL T Sbjct: 62 TEPNAAQEVYNFVKFSKIEIDYLINNAGF--GGIGKFHERAWAQDLAMIQLNIIALTDLT 119 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 K + + + GK ++NVSS A+L + +YFATK+ V FSN + H +K Sbjct: 120 RKFLPDFVERNQGK---ILNVSSTASLMAGPMQAVYFATKAFVTSFSNAIAEELHDTK-- 174 Query: 524 VRVLTVCFGATDT 562 V V T+ GAT T Sbjct: 175 VTVTTLMPGATKT 187 >UniRef50_A1BFL6 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Chlorobium/Pelodictyon group|Rep: Short-chain dehydrogenase/reductase SDR precursor - Chlorobium phaeobacteroides (strain DSM 266) Length = 280 Score = 72.5 bits (170), Expect = 8e-12 Identities = 57/199 (28%), Positives = 99/199 (49%), Gaps = 6/199 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K +TGAA+GIG ++ L++ G + + + DI + AG + G DV Sbjct: 8 KNAIVTGAASGIGFALAVGLIERGAR-VWVADI-DSAGVERAA---ASLGAGAHPVTLDV 62 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 349 + F ++ V ++ GGID + NNA +++ + I+VN+ ++ TL Sbjct: 63 RDAVAFRDLVAGVARDAGGIDFLFNNAGILHSGEVCEFDEEQCNRIIDVNIRGVVNGTLA 122 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 A +M + + G ++N +S+A L + ++ Y TK AV+ FS+ + R E + GVR Sbjct: 123 AYPLMVRQ---RSGHIVNTASLAGLAPAPLLSTYAMTKHAVVGFSSSL-RFE-AERYGVR 177 Query: 530 VLTVCFGATDTALLTDEKL 586 V +C DT LL +E + Sbjct: 178 VSAICPAGVDTPLLDEEAI 196 >UniRef50_Q2U0U8 Cluster: Dehydrogenases with different specificities; n=2; Pezizomycotina|Rep: Dehydrogenases with different specificities - Aspergillus oryzae Length = 271 Score = 72.5 bits (170), Expect = 8e-12 Identities = 57/215 (26%), Positives = 101/215 (46%), Gaps = 23/215 (10%) Frame = +2 Query: 11 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN------KTKF 172 + ITGAA+GIG + +G IA+LD+ + A +++Q E+NS+ + + Sbjct: 6 IALITGAASGIGRACAHTFARDGASGIALLDLDKTALETVQAEINSQSSQDKTARCRVEI 65 Query: 173 YRSDVTNEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGI-------YKKAIEVNVTA 328 Y +VT+E ++N+ Q +D V+N A + M G +++ ++VN+T Sbjct: 66 YPVNVTDENRVDEVINSAAQTFSRLDYVVNAAGIAMKHQGGAAFAETSDWQRILDVNLTG 125 Query: 329 LITSTLKAIEIMGKHS------GGK---GGTVINVSSVAALTQSHVMPIYFATKSAVLQF 481 A IM G+ G+++N SS+ + + Y ATK AV+ Sbjct: 126 TFFVLRAAARIMLSQEPIRSSIDGRPLQRGSIVNFSSIQGVAGIPLSTAYTATKHAVIGL 185 Query: 482 SNCVGRPEHFSKTGVRVLTVCFGATDTALLTDEKL 586 + E ++K G+R+ +C G T+T + T L Sbjct: 186 TRTAS--EDYAKDGLRINAICPGYTETPMTTKSPL 218 >UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627; n=13; Bacteria|Rep: Uncharacterized oxidoreductase SSP1627 - Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 /DSM 20229) Length = 246 Score = 72.5 bits (170), Expect = 8e-12 Identities = 58/196 (29%), Positives = 91/196 (46%), Gaps = 7/196 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 178 KDKVV ITGA++GIGE V +L + G K L + L+ ++ K G + + Sbjct: 5 KDKVVVITGASSGIGEETVNLLSENGAK----LVLGARRLDRLE-KIQQKVGHDSVSIKK 59 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 340 +DVT + ++ + G IDV+INNA LM S + + I+VN+ ++ Sbjct: 60 TDVTKPDEVNALIETAYNDFGRIDVLINNAGLMPQSFLEKNKQDEWNQMIDVNIKGVLYG 119 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 + M K K G +IN++SVA +Y TK AV + + + E + Sbjct: 120 IGAVLPYMRKQ---KSGHIINLASVAGHVVFPGSAVYCGTKYAVRAITEGLRQEEAIVGS 176 Query: 521 GVRVLTVCFGATDTAL 568 +R + GA T L Sbjct: 177 NIRTTILSPGAVSTEL 192 >UniRef50_P66778 Cluster: Probable oxidoreductase ephD; n=16; Mycobacterium|Rep: Probable oxidoreductase ephD - Mycobacterium bovis Length = 592 Score = 72.5 bits (170), Expect = 8e-12 Identities = 56/195 (28%), Positives = 91/195 (46%), Gaps = 6/195 (3%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 D +V +TGA +GIG EG + I I DI E K E+ ++ G Y D Sbjct: 324 DTLVSVTGAGSGIGRETALAFAREGAE-IVISDIDEATVKDTAAEIAAR-GGIAYPYVLD 381 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTL 346 V++ E V E G D+V+NNA + ++ + + + VN+ ++ Sbjct: 382 VSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNGCR 441 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 + + + G GG ++NVSS+AA + Y +K+A FS+C+ R E GV Sbjct: 442 AFGQRLVER--GTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCL-RAE-LDAAGV 497 Query: 527 RVLTVCFGATDTALL 571 + T+C G DT ++ Sbjct: 498 GLTTICPGVIDTNIV 512 >UniRef50_Q7M9W0 Cluster: 3-OXOACYL-REDUCTASE; n=24; Epsilonproteobacteria|Rep: 3-OXOACYL-REDUCTASE - Wolinella succinogenes Length = 247 Score = 72.1 bits (169), Expect = 1e-11 Identities = 54/217 (24%), Positives = 97/217 (44%), Gaps = 7/217 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K V ITG++ GIG + R+L + G+K L+ E+ +K G + D Sbjct: 6 KNVLITGSSRGIGADIARVLAEMGLKVWINYRSQSSLADELKAEIEAK-GGQAAVISFDA 64 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 349 T+EE F+ + ++ G + ++NNA + ND + I ++ IE N+T+ + + Sbjct: 65 TDEEAFISGIKTIIDADGELAYLVNNAGITNDKLAIRMKTEEFRSVIEANLTSAFIGSRE 124 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 A++ M K + G+V+N+SS+ + Y A+K ++ + Sbjct: 125 ALKSMSKQ---RFGSVVNISSIVGERGNAGQTNYSASKGGMIAMTKSFAFEGAPRNVRFN 181 Query: 530 VLTVCFGATD-TALLTDEKLGTFDKYLEFFMLGPTKE 637 +T F TD T L +E + K + G +KE Sbjct: 182 CVTPGFIQTDMTHGLKEEVKEAYIKNIPLGRFGDSKE 218 >UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 251 Score = 72.1 bits (169), Expect = 1e-11 Identities = 58/203 (28%), Positives = 95/203 (46%), Gaps = 6/203 (2%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K +TGA +GIG ++ EG + +A+ D+ E A + + E+ G R+DV Sbjct: 7 KRTIVTGAGSGIGRAIALRFAAEGAR-VALADVDEGAARKVAAEI----GEGCLVQRTDV 61 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 349 T E G++ + GG++V++NNA + S +++ + VN+ Sbjct: 62 TVAEEVEGLVRLATERWGGLEVMVNNAGVGVAATAPQTSEEDFERVLAVNLRGTFLGMKY 121 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 AI + + SG GG VIN+SS+AAL Y A K +L + G +H + GVR Sbjct: 122 AIPAI-RDSG--GGAVINMSSIAALVGLKDRAAYSAAKGGILALTR-AGAIDHIHE-GVR 176 Query: 530 VLTVCFGATDTALLTDEKLGTFD 598 V + G +T ++ G D Sbjct: 177 VNCIAPGTVETPWISRITAGYAD 199 >UniRef50_Q0GL61 Cluster: Short-chain dehydrogenase; n=3; Lactobacillus reuteri|Rep: Short-chain dehydrogenase - Lactobacillus reuteri Length = 277 Score = 72.1 bits (169), Expect = 1e-11 Identities = 66/195 (33%), Positives = 101/195 (51%), Gaps = 8/195 (4%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKY----GNKTK 169 +++VV ITG ++GIG+ L E + AI+ + + LQ E+ K G Sbjct: 12 RNEVVLITGGSSGIGKE----LAFEAARRGAIVVVVSRNLEKLQ-EVAKKCLILSGRPAF 66 Query: 170 FYRSDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 349 Y+ DVT+ + +L+ V E GGIDV+IN+A L D I + K++ + T+ L Sbjct: 67 AYQLDVTDPDQIDDVLSKVQHEVGGIDVLINSAGL-GDFIPVVKESYSSMEKMVHTNLLA 125 Query: 350 AIEI---MGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSK 517 + I + K +G G +IN+ S+A + +Y ATK+ V+QF N V R E + Sbjct: 126 LMYISRCVAKQMMDQGYGAIINMGSLAGKLPTPNSAVYSATKAGVIQFDN-VLRME-VAD 183 Query: 518 TGVRVLTVCFGATDT 562 GV+VLTV G DT Sbjct: 184 YGVQVLTVNPGPIDT 198 >UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bacterium HTCC2150|Rep: Dehydrogenase - Rhodobacterales bacterium HTCC2150 Length = 279 Score = 72.1 bits (169), Expect = 1e-11 Identities = 55/199 (27%), Positives = 96/199 (48%), Gaps = 7/199 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDI-AEEAGKSLQVELNSKYGNKTKFYR 178 K+K V +TGAA G+G + L +G ++ + D+ AE+ +S+Q + ++ Sbjct: 23 KNKTVIVTGAAQGLGYACALRFLQDGA-NVVMADVNAEKLAESVQDLI--EFDGAVSSMV 79 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSIGIYKKAIEVNVTALITSTLKA 352 DVT E+ ++ V G +DV+INNA + + D + I + + + Sbjct: 80 CDVTKRENLQALVGLAVSNYGNLDVMINNAGIAKVQDFLEISDDEYDAVMDVNLRGAFIG 139 Query: 353 IEIMGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN--CVGRPEHFSKT 520 +I GK + GKGG +IN+SS+ AL + ++ Y +K + Q +N VG H Sbjct: 140 TQIAGKQMIAQGKGGVIINMSSINALVANPMLSTYAISKGGMNQLTNIAAVGLAPH---- 195 Query: 521 GVRVLTVCFGATDTALLTD 577 +RV + G T ++ D Sbjct: 196 NIRVCGIGPGTILTDMVAD 214 >UniRef50_A2U8H9 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Bacillus coagulans 36D1|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus coagulans 36D1 Length = 262 Score = 72.1 bits (169), Expect = 1e-11 Identities = 52/195 (26%), Positives = 91/195 (46%), Gaps = 7/195 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TG GIG + L G ++ + D+++E G+ ++ G + F R+DV Sbjct: 9 KVAIVTGGGGGIGREAC-LKLAAGGANVVVADLSDELGEETAGKIREN-GGEAIFVRTDV 66 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 346 + + + + G ID+++NNA L++ ++ K + +NV + Sbjct: 67 SKSKDVQHYVRTALDTYGKIDILLNNAGWEGKMKPLIDYPEEVFDKLMGINVRGVFLGMK 126 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 + M K GT++N +SVA L + M Y A+K AV+ + G + +GV Sbjct: 127 YVLPHMISQ---KSGTIVNTASVAGLVGTPEMVAYGASKHAVIGMTKTAG--IEAAPSGV 181 Query: 527 RVLTVCFGATDTALL 571 RV VC G DT ++ Sbjct: 182 RVNAVCPGVVDTEMM 196 >UniRef50_A0VFC2 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Delftia acidovorans SPH-1|Rep: Short-chain dehydrogenase/reductase SDR - Delftia acidovorans SPH-1 Length = 301 Score = 72.1 bits (169), Expect = 1e-11 Identities = 61/192 (31%), Positives = 90/192 (46%), Gaps = 6/192 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K V +TGA+ GIGE R L G K + I + K L EL +F D+ Sbjct: 51 KTVLVTGASMGIGEVFARELARRGAKVVLIARSRDRLEK-LASELPG-----AEFLVEDL 104 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 349 + +AV D+++NNA ++ + ++ I++NV AL+ T Sbjct: 105 ATPGAARRVFDAVSARGLLPDLLVNNAGFGTHGRFDELALDMQRETIDLNVGALVELTHL 164 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 + + + GG VIN++S AA M +Y ATK+ VL FS + + GVR Sbjct: 165 CLPALEQRQGG----VINIASTAAFQPVPYMAVYAATKAFVLSFSEALW--AEYRPRGVR 218 Query: 530 VLTVCFGATDTA 565 VL +C GATDTA Sbjct: 219 VLALCPGATDTA 230 >UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; n=28; Bacteria|Rep: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase - Mycobacterium bovis Length = 260 Score = 72.1 bits (169), Expect = 1e-11 Identities = 53/193 (27%), Positives = 96/193 (49%), Gaps = 6/193 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV ++G A G+G S VR ++ EG K + DI +E GK++ EL + ++ DV Sbjct: 8 KVALVSGGARGMGASHVRAMVAEGAK-VVFGDILDEEGKAVAAEL----ADAARYVHLDV 62 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 349 T + ++ V GG+ V++NNA ++N ++ +++ ++VN+T + Sbjct: 63 TQPAQWTAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTGVFLGIRA 122 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 ++ M K +G G++IN+SS+ L + Y ATK AV + +G+R Sbjct: 123 VVKPM-KEAG--RGSIINISSIEGLAGTVACHGYTATKFAVRGLTKSTAL--ELGPSGIR 177 Query: 530 VLTVCFGATDTAL 568 V ++ G T + Sbjct: 178 VNSIHPGLVKTPM 190 >UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 248 Score = 71.7 bits (168), Expect = 1e-11 Identities = 57/193 (29%), Positives = 93/193 (48%), Gaps = 5/193 (2%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV ITGA +GIG ++ R+ EG K + + D+A E G +L L + G+ F DV Sbjct: 7 KVAVITGAGSGIGAAIARLFAVEGAK-VLLGDLA-EGGAALAAGLAAD-GHAAGFQHVDV 63 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 367 T+E ++ A V G +D+++ NA + I++ + V+ +I L + I Sbjct: 64 TDEASVAELMQAAVTLFGRLDILVANAGIPERKSPIHELDL-VDWRRVIDVDLTGVAICN 122 Query: 368 KHSGG-----KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532 K + G GG ++N++S+ A Y A K+AV+ + V ++ G+R Sbjct: 123 KFAAGIMRATGGGAIVNMASILAHVGQENSNAYSAAKAAVVNLTRSVALT--YALQGIRA 180 Query: 533 LTVCFGATDTALL 571 V G DT LL Sbjct: 181 NCVSPGYVDTPLL 193 >UniRef50_Q48I17 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Pseudomonas syringae pv. phaseolicola 1448A|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Pseudomonas syringae pv. phaseolicola (strain 1448A / Race 6) Length = 282 Score = 71.7 bits (168), Expect = 1e-11 Identities = 59/198 (29%), Positives = 101/198 (51%), Gaps = 6/198 (3%) Frame = +2 Query: 11 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVT 190 VV ITGAA GIG+++ L+ G++ I + DI E K L+V L G Y D+T Sbjct: 4 VVLITGAAGGIGQAICAQLIRRGMQLI-LADIDE---KQLRV-LAESLGEDAFPYVVDLT 58 Query: 191 NEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTLKA 352 N+E G++ + E G +DV+INNAA+ S+ + + +N+ A + T A Sbjct: 59 NQESLAGLMTYIESEFGRLDVLINNAAIAVVEAFDTRSVESISRELNINLVAPLILTRLA 118 Query: 353 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532 I ++ + + + VI+ S+ + + PIY A+K + +G ++ G++V Sbjct: 119 IPLLKRSNDAR---VISTVSLGGVFPTPESPIYCASKFGLRGAMLSIGL--DLAEKGIKV 173 Query: 533 LTVCFGATDTALLTDEKL 586 ++ ATDT +L E + Sbjct: 174 GSILPTATDTQMLRKEAI 191 >UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=4; Clostridiales|Rep: 7-alpha-hydroxysteroid dehydrogenase - Clostridium perfringens (strain SM101 / Type A) Length = 253 Score = 71.7 bits (168), Expect = 1e-11 Identities = 63/205 (30%), Positives = 97/205 (47%), Gaps = 10/205 (4%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-YR 178 K+KVV +TG GIG + V+ LD G K +A+ +E ELN N + Sbjct: 9 KNKVVIVTGGTRGIGFATVKKFLDHGAK-VALCGSRKETVDKALEELNYINPNYDAIGFY 67 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALIT 337 ++ + +++ V+++ G ID++INNA ++D+ IY K I++NV A+ Sbjct: 68 PNLLDSNEVKEMVDKVLEKWGTIDILINNAG-VSDNKSIYTQSDEDFSKIIDINVKAIFN 126 Query: 338 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSK 517 T EIM K G ++N SSV +L Y +K AV + + R + Sbjct: 127 CTKAVSEIM---KNKKYGVILNTSSVVSLYGQKTGVGYPTSKFAVNGLTKSLAR--ELGR 181 Query: 518 TGVRVLTVCFG--ATDTALLTDEKL 586 G+RV V G ATD D+KL Sbjct: 182 DGIRVNAVAPGIIATDMVAALDKKL 206 >UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=3; Proteobacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Erythrobacter sp. NAP1 Length = 267 Score = 71.7 bits (168), Expect = 1e-11 Identities = 61/211 (28%), Positives = 103/211 (48%), Gaps = 7/211 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K V ITG++ GIGE + R EG + AE+ K L++ ++T DV Sbjct: 10 KTVIITGSSAGIGEGIARRFHAEGANVVINARNAEKCAKVADT-LDA---DRTLTCPGDV 65 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-------KAIEVNVTALITSTL 346 ++ + I+ V+ GG+D ++NNA + S+ ++K + I++NV +I Sbjct: 66 SSSDFANEIVAKTVERFGGLDCLVNNAGVGGSSM-LHKTDDEEIDRIIDINVKGVIYLCR 124 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 AI + K GG++IN+SSV+ + ++PIY A+K A+ + G + G+ Sbjct: 125 AAIPHLRKSEAVGGGSIINISSVSGIGGDSMLPIYNASKGAMTNLTR--GLAQQIGGMGI 182 Query: 527 RVLTVCFGATDTALLTDEKLGTFDKYLEFFM 619 RV + T + ++ D L D LE FM Sbjct: 183 RVNAINPSITRSDMV-DGILAN-DALLEAFM 211 >UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 253 Score = 71.7 bits (168), Expect = 1e-11 Identities = 54/192 (28%), Positives = 88/192 (45%), Gaps = 5/192 (2%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KVV ITG ATGIG + +G + + + D+ + A ++ V L + G F R+DV Sbjct: 10 KVVLITGGATGIGRATALAFAQQGAR-VVVGDVDDRAAET--VRLIEESGGTALFVRTDV 66 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 367 T+ ++ V GG+ V NNA ++ + G + E + I LK + + Sbjct: 67 TSAADVQQLVRTTVDTYGGLHVAFNNAGILPPT-GPLAEQSEDDFDRTIAVDLKGVFLAL 125 Query: 368 KH-----SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532 K+ + GG++IN +SVA + M Y A K V+ + ++ GVRV Sbjct: 126 KYEIEHMAAAGGGSIINTASVAGVIADPGMAPYVAAKHGVVGLTRAAA--IDYAAAGVRV 183 Query: 533 LTVCFGATDTAL 568 + G DT + Sbjct: 184 NALAPGLVDTPM 195 >UniRef50_A0Z215 Cluster: Short chain dehydrogenase; n=2; Gammaproteobacteria|Rep: Short chain dehydrogenase - marine gamma proteobacterium HTCC2080 Length = 291 Score = 71.7 bits (168), Expect = 1e-11 Identities = 48/181 (26%), Positives = 86/181 (47%), Gaps = 2/181 (1%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K + ITGAA+G+G ++ + EG + I DI +E G + +LN +Y N F ++ Sbjct: 2 KRILITGAASGLGLALAKKYASEGWS-VCIADIQDEEGIKIAAQLNEEYANDCFFQHLNI 60 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGIYK-KAIEVNVTALITSTLKAIEI 361 T++ + ++ + + G+D ++NNA + + I + K + V + +K + Sbjct: 61 TSDTQWQELVALISERWQGLDALVNNAGVGASGDIDTFSIKDFQWTVDINLMGAVKGCHV 120 Query: 362 MGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVLTV 541 G +INV+S+A L M Y +K+ ++ FS G GV+V V Sbjct: 121 CVPLLKESKGLLINVASMAGLLHMGSMSAYNVSKAGMVAFSE--GLLSELDPYGVKVSVV 178 Query: 542 C 544 C Sbjct: 179 C 179 >UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=18; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Arthrobacter sp. (strain FB24) Length = 263 Score = 71.7 bits (168), Expect = 1e-11 Identities = 58/208 (27%), Positives = 98/208 (47%), Gaps = 18/208 (8%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK-FYR 178 K V ITG A+G+G + R L D G + ++D+ G++ ELN+ G T F Sbjct: 4 KGTVALITGGASGLGAATARRLFDAGAS-VVLVDLPSSRGEAFAAELNAASGAGTAVFVP 62 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDS----------IGIYKKAIEV---- 316 +DVT+EE + A V G + +V+N A + + + + I++ Sbjct: 63 ADVTSEEQVQAAVAAAV-ALGPLRIVVNCAGIATPGKVLGRDGVLPLDTFSRVIQINLVG 121 Query: 317 --NVTALITSTLKAIEIMGKHSGG-KGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSN 487 NV L + + A E + GG + G +IN +SVAA P Y A+K AV + Sbjct: 122 TFNVIRLAAAAMAATEPVSTELGGPERGVIINTASVAAFDGQIGQPAYAASKGAVAAMTL 181 Query: 488 CVGRPEHFSKTGVRVLTVCFGATDTALL 571 + R +++ +RV+T+ G +T ++ Sbjct: 182 PIAR--ELARSLIRVVTIAPGIFETPMM 207 >UniRef50_A7EQI6 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 249 Score = 71.7 bits (168), Expect = 1e-11 Identities = 51/188 (27%), Positives = 93/188 (49%), Gaps = 7/188 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K+KV +TG +G GE++ R EG K + I DI G+ + + + + F + Sbjct: 15 KNKVAIVTGGGSGFGEAIARRFAGEGCK-VTIADIDAVGGERVA----NVHPHSMLFVKM 69 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALM---NDSIGI----YKKAIEVNVTALITS 340 DVTNEE + +L + + G +DV +NNA ++ + + K VNV ++ + Sbjct: 70 DVTNEEDWERVLETTLAKWGRVDVCVNNAGTSYRNKPTLDVIEDEFDKVFNVNVKSIFYA 129 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 T I + G+GG++IN++S+ A + Y A+K+AV+ + G + Sbjct: 130 TRHFIP--NVINQGEGGSMINIASIGASRPRAGLVWYNASKAAVVNATK--GLAAEYGPK 185 Query: 521 GVRVLTVC 544 +R+ ++C Sbjct: 186 NIRINSIC 193 >UniRef50_Q5UYC2 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=2; Halobacteriaceae|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Haloarcula marismortui (Halobacterium marismortui) Length = 254 Score = 71.7 bits (168), Expect = 1e-11 Identities = 55/211 (26%), Positives = 98/211 (46%), Gaps = 9/211 (4%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE---EAGKSLQVELNSKYGNKTKF 172 +DKV +TG A+G G ++ R + G + + D + E GK + ++ F Sbjct: 6 EDKVAVVTGGASGFGRAICRRYAEHGA-DVIVADRQQDPREGGKPTHELVEAETDRTAHF 64 Query: 173 YRSDVTNEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALI 334 DVT+ + L + A +E GGID+++NNA + + Y + ++VN + Sbjct: 65 VECDVTDPDD-LEVAVAAAEELGGIDIMVNNAGISEIADFYETTEEDYDRLMDVNTKGVF 123 Query: 335 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFS 514 A E M ++ GGTVIN+SS + + ++ Y +K AV F+ + + S Sbjct: 124 FGAQVATEAMRENG---GGTVINMSSSGGIRGTGLLVNYCTSKGAVRLFTYALA--DRLS 178 Query: 515 KTGVRVLTVCFGATDTALLTDEKLGTFDKYL 607 +RV + G + T + DE++ K + Sbjct: 179 NYNIRVNAIHPGYSKTQMFEDERIDDTTKMM 209 >UniRef50_UPI00015B4F48 Cluster: PREDICTED: similar to ENSANGP00000025535; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to ENSANGP00000025535 - Nasonia vitripennis Length = 254 Score = 71.3 bits (167), Expect = 2e-11 Identities = 58/198 (29%), Positives = 99/198 (50%), Gaps = 8/198 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TGA+ GIG ++V LLD G + ++ +A K ++ ++ + K DV Sbjct: 7 KVAVVTGASVGIGAAIVNKLLDNG---LIVVGLARRVEKVKEL-IDDRPEAKLHAVECDV 62 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITSTLK 349 TNEE+ + + + G +DV++NNA L + S+ ++ ++VNV L T + Sbjct: 63 TNEENVVTAFAWIKENLGSVDVLVNNAGVTKETTLSDGSLADWRNVLDVNVLGLCVCTRE 122 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHV--MPIYFATKSAVLQFSNCVGRPEHFSKTG 523 A+ M + G +I++SS+A V +Y ATK AV + + R E + T Sbjct: 123 AVRSMRECDG--ESVIIHISSLAGERVPAVPGFNVYPATKRAVNALAQTL-RHE-LAGTK 178 Query: 524 VRVLTVCFGATDTALLTD 577 +RV T+ G T L+ + Sbjct: 179 IRVTTISPGLVATELMAN 196 >UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Leptospira interrogans Length = 259 Score = 71.3 bits (167), Expect = 2e-11 Identities = 50/192 (26%), Positives = 95/192 (49%), Gaps = 7/192 (3%) Frame = +2 Query: 8 KVVFITGAAT--GIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 KV +TGAA+ G+G ++ + EG I ++D+ +E + ++ ++G KT Sbjct: 12 KVALVTGAASPRGLGRAIANTIAKEG-GDIVLVDLNKEQIEQAAADVAKEFGVKTLGLSC 70 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 361 +VT E ++ V ++ G +D ++NNA ++ D++ I + E ++ LK + + Sbjct: 71 NVTKPEDCDSVIAGVKEKFGKLDFLVNNAGVLKDNLFI--RMSEQEFDFVLDVNLKGVFL 128 Query: 362 MGKHSG-----GKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 M K++ + G ++N+SSV+ LT Y ++K+ V+ + R F+ V Sbjct: 129 MTKYASKLLLKAESGRIVNISSVSGLTGQPGQANYSSSKAGVIALTKVAAR--EFAGRNV 186 Query: 527 RVLTVCFGATDT 562 V VC G T Sbjct: 187 LVNAVCPGYVQT 198 >UniRef50_Q0S5L2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=3; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus sp. (strain RHA1) Length = 258 Score = 71.3 bits (167), Expect = 2e-11 Identities = 52/184 (28%), Positives = 87/184 (47%), Gaps = 6/184 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K + +TG A GIG ++V+ EG + D+ EE G+ + E + +F R D+ Sbjct: 6 KRILVTGGAQGIGAAIVKAYAMEGAT-VRSYDLNEEGGRVVAEEASDAGPGVVEFSRLDI 64 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG------IYKKAIEVNVTALITSTLK 349 T+ + + + +E GGIDV++N A L ++ +++ VNV I + Sbjct: 65 TDGDATESLFRSAARELGGIDVLVNIAGLQRSAMAEEITDDLFESIYRVNVLGTIHTNQS 124 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 A IM S G G +IN S++ T Y ++K AV ++ V R + +G+R Sbjct: 125 AYRIM--QSAGT-GAIINFGSMSGFTGELANATYGSSKGAVHTWTRTVAR--EWGPSGIR 179 Query: 530 VLTV 541 V V Sbjct: 180 VNAV 183 >UniRef50_A7AZH2 Cluster: Putative uncharacterized protein; n=1; Ruminococcus gnavus ATCC 29149|Rep: Putative uncharacterized protein - Ruminococcus gnavus ATCC 29149 Length = 276 Score = 71.3 bits (167), Expect = 2e-11 Identities = 51/195 (26%), Positives = 94/195 (48%), Gaps = 7/195 (3%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 +K++ +TGA +GIG +V EG +A+ EE G ++ V + G K +F + D Sbjct: 13 EKIMLVTGATSGIGRAVAIRAAKEGATVVAV-GRNEERGAAV-VAAMEEAGGKGEFMKCD 70 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITST 343 V+N++ + + ++ G +DV +NNA ++ S + + + I+ N+ + Sbjct: 71 VSNKDAVKALFAEIQEKYGKLDVAVNNAGIVGASKTVEELEDDDWFQVIDANLNSCFFCC 130 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 + +++M GG ++NVSSVA + Y A+K AV + V ++ G Sbjct: 131 REEVKLMQP----SGGAIVNVSSVAGMRGFPSAAAYVASKHAVSGLTKAVA--VDYATKG 184 Query: 524 VRVLTVCFGATDTAL 568 + +C TDT L Sbjct: 185 ITCNAICPAGTDTPL 199 >UniRef50_A1SJV4 Cluster: Short-chain dehydrogenase/reductase SDR; n=9; cellular organisms|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 259 Score = 71.3 bits (167), Expect = 2e-11 Identities = 54/198 (27%), Positives = 93/198 (46%), Gaps = 8/198 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 +V ITG +GIG + V+ + EG K + I DI + G L +L + + DV Sbjct: 8 RVAVITGGCSGIGLATVQRFVQEGAK-VVIGDIDDARGHQLVEQLGG--ADVATYVHVDV 64 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNA--------ALMNDSIGIYKKAIEVNVTALITST 343 T++E + G +D+ NNA ++++ + ++K EVN+T++ Sbjct: 65 TSKEQVDALFQTAKDAYGSVDIAFNNAGISPPEDDSILDTDLDAWRKVQEVNLTSVYLCC 124 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 A+ M + G+G + S VA + + Y A+K VL + +G F++ G Sbjct: 125 KAALPHMLEQ--GRGSIINTASFVAVMGAATSQISYSASKGGVLSMTRELG--VQFARQG 180 Query: 524 VRVLTVCFGATDTALLTD 577 VRV +C G +T LL + Sbjct: 181 VRVNALCPGPVNTPLLQE 198 >UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=26; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Chlamydia pneumoniae (Chlamydophila pneumoniae) Length = 248 Score = 71.3 bits (167), Expect = 2e-11 Identities = 52/197 (26%), Positives = 96/197 (48%), Gaps = 7/197 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K V +TG + GIG +V++ L+ G + I + EE G+++ +E + G + F R DV Sbjct: 8 KKVIVTGGSRGIGLGIVKLFLENGAD-VEIWGLNEERGQAV-IESLTGLGGEVSFARVDV 65 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 349 ++ + + + ID+++NNA + D++ + ++ I N+T+L + Sbjct: 66 SHNGGVKDCVQKFLDKHNKIDILVNNAGITRDNLLMRMSEDDWQSVISTNLTSLYYTCSS 125 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 I M K + G++INV+S+ A S Y A K+ ++ F+ + + V Sbjct: 126 VIRHMIK---ARSGSIINVASIVAKIGSAGQTNYAAAKAGIIAFTKSLAKEVAARNIRVN 182 Query: 530 VLTVCFGATD-TALLTD 577 L F TD T++L D Sbjct: 183 CLAPGFIETDMTSVLND 199 >UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60; Bacteria|Rep: Sorbitol dehydrogenase - Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides) Length = 256 Score = 71.3 bits (167), Expect = 2e-11 Identities = 51/188 (27%), Positives = 95/188 (50%), Gaps = 4/188 (2%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K ITG+A GIG + + EG + +AI DI EA ++ E+ G DV Sbjct: 6 KTALITGSARGIGRAFAEAYVREGAR-VAIADINLEAARATAAEI----GPAACAIALDV 60 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDS--IGIYKKAIEVNVTALITSTLKAIEI 361 T++ + ++ G ID+++NNAAL + + + I +++ + ++ TL ++ Sbjct: 61 TDQASIDRCVAELLDRWGSIDILVNNAALFDLAPIVEITRESYDRLFAINVSGTLFMMQA 120 Query: 362 MGKH--SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535 + + +GG+GG +IN++S A ++ +Y ATK+AV+ + G + + G+ V Sbjct: 121 VARAMIAGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGL--NLIRHGINVN 178 Query: 536 TVCFGATD 559 + G D Sbjct: 179 AIAPGVVD 186 >UniRef50_Q3IVD0 Cluster: Short-chain alcohol dehydrogenases; n=2; Rhodobacteraceae|Rep: Short-chain alcohol dehydrogenases - Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM158) Length = 247 Score = 70.9 bits (166), Expect = 2e-11 Identities = 58/201 (28%), Positives = 98/201 (48%), Gaps = 6/201 (2%) Frame = +2 Query: 14 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTN 193 + ITGA +GIG R EG +A++D E A QV + G+ + DVT+ Sbjct: 10 IVITGAGSGIGRESARQFAREGAT-LALIDRDEAAA---QVTADETGGH---VFALDVTD 62 Query: 194 EEHFLGILNAVVQEQGGIDVVINNAALMN----DSIGI--YKKAIEVNVTALITSTLKAI 355 E ++ + GGID ++N+A ++ D IG+ +++ ++VN+T A+ Sbjct: 63 EAAVETVVGRAAEALGGIDGLLNSAGILTMKTVDDIGVEEFRRVVDVNLTGTFLVCQAAL 122 Query: 356 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535 + K ++N++S AL S Y A+K+AV+ FS + + VRV Sbjct: 123 PWLRKE---PKAAIVNIASAQALLPSLTGSAYAASKAAVMMFSKSIAKE---LAPAVRVN 176 Query: 536 TVCFGATDTALLTDEKLGTFD 598 +C GAT+T +TD+ + D Sbjct: 177 IICPGATETP-MTDQGVAPDD 196 >UniRef50_Q03X86 Cluster: Putative uncharacterized protein; n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293|Rep: Putative uncharacterized protein - Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 /NCDO 523) Length = 247 Score = 70.9 bits (166), Expect = 2e-11 Identities = 62/201 (30%), Positives = 98/201 (48%), Gaps = 9/201 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV+ ITGA++GIGE++ + G K I + EE K ++ ++ + G + ++ +DV Sbjct: 5 KVIVITGASSGIGEAIAKKQAAAGDK-IVLGARREENLKQIKADIEAG-GGQAEYLVTDV 62 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 349 T+ E + + G IDV INNA LM S+ I + + I+VN+ + Sbjct: 63 TDVEQVKALAQKAMDAYGRIDVWINNAGLMPHSLLIDARIDDWNRMIDVNLKGTLYGIAA 122 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 A I + G IN+ SVA+L +Y ATK AV S + E + VR Sbjct: 123 AQHIFHDQNTGH---FINLGSVASLYSHAGGAVYSATKWAVKAISESLREEEAQAGKNVR 179 Query: 530 VLTVCFGATDTAL---LTDEK 583 V ++ GA ++ L +TD K Sbjct: 180 VTSLYPGAIESELVANMTDSK 200 >UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5; Proteobacteria|Rep: Short chain dehydrogenase - Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) Length = 278 Score = 70.9 bits (166), Expect = 2e-11 Identities = 60/193 (31%), Positives = 86/193 (44%), Gaps = 7/193 (3%) Frame = +2 Query: 14 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTN 193 V ITGA TGIG + EG + +A+ EEAG +L EL + GN+ +F +DV Sbjct: 35 VLITGALTGIGRATAFAFAREGYR-VAVSGRREEAGNALAAELRA-LGNEAEFLLADVRF 92 Query: 194 EEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTLKA 352 E ++ V G IDV +NNA ++ S Y + VNV + S Sbjct: 93 EADVRNLVEQTVVRFGRIDVAVNNAGTEGQLAPIVEQSAANYAETFGVNVLGTMLSLKHE 152 Query: 353 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532 + +M G++IN+SSVA +Y A+K AV + + GVRV Sbjct: 153 MRVMLAQG---SGSIINLSSVAGKVGIAGASVYVASKHAVEGLTKSAAL--EGAAAGVRV 207 Query: 533 LTVCFGATDTALL 571 V G T +L Sbjct: 208 NAVAPGPVATEML 220 >UniRef50_Q0D3V4 Cluster: Os07g0664000 protein; n=34; cellular organisms|Rep: Os07g0664000 protein - Oryza sativa subsp. japonica (Rice) Length = 572 Score = 70.9 bits (166), Expect = 2e-11 Identities = 57/197 (28%), Positives = 88/197 (44%), Gaps = 9/197 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV ITG A+GIG++ + G K + I DI ++ G S+ EL G + R DV Sbjct: 314 KVAVITGGASGIGKATATEFIKNGAK-VIIADIQDDLGHSVAAEL----GPDAAYTRCDV 368 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNA----ALMND-----SIGIYKKAIEVNVTALITS 340 +E + V+ G +DV NNA AL D +G + + + VN + + + Sbjct: 369 ADEAQVAAAVGLAVKRHGRLDVFHNNAGIAGALPQDDMAAVDLGDFDRVMAVNARSTLAA 428 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 A M G V+ SS A + +P+Y +K+ V+ P ++ Sbjct: 429 VKHAARAMAPRC---SGCVLCTSSGAGVIPVPAVPVYSVSKATVIAIVRAAAEP--MARH 483 Query: 521 GVRVLTVCFGATDTALL 571 G+RV + GAT T LL Sbjct: 484 GLRVNAISPGATRTPLL 500 >UniRef50_Q7SI45 Cluster: Putative uncharacterized protein NCU00606.1; n=2; Sordariales|Rep: Putative uncharacterized protein NCU00606.1 - Neurospora crassa Length = 262 Score = 70.9 bits (166), Expect = 2e-11 Identities = 48/198 (24%), Positives = 96/198 (48%), Gaps = 8/198 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K V TGAA G+G+ + L G ++ I D+ ++ +++ E Y ++ ++DV Sbjct: 7 KTVLATGAAGGLGKVIAETFLAAGA-NVIICDVNQQRNSAVEEEWTRTYADRFLIKQTDV 65 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITSTL 346 +NE +++A V + G +DV++NNAA+M+D S ++ + + +N+T +T Sbjct: 66 SNEAAVQELIDASVAKFGRLDVLVNNAAIMDDFSPAGDCSKELWDRVMAINLTGPFLTTK 125 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS-NCVGRPEHFSKTG 523 A++ K GG +IN+ S A+ Y +K+ ++ + N G ++ G Sbjct: 126 AAVKQFEKQKQA-GGIIINIGSNASYMGFQSGAAYTVSKAGIMALTKNTAG---FYADKG 181 Query: 524 VRVLTVCFGATDTALLTD 577 + + + G + D Sbjct: 182 IYTMALLLGGLTGTNIVD 199 >UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family member 10; n=19; Eumetazoa|Rep: Dehydrogenase/reductase SDR family member 10 - Homo sapiens (Human) Length = 270 Score = 70.9 bits (166), Expect = 2e-11 Identities = 61/195 (31%), Positives = 93/195 (47%), Gaps = 8/195 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KVV +TG GIG +VR ++ G + + I D E G++L+ EL F DV Sbjct: 10 KVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQELPG-----AVFILCDV 63 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 346 T E+ +++ ++ G +D V+NNA S +++ +E+N+ T T Sbjct: 64 TQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTK 123 Query: 347 KAIEIMGKHSGGKGGTVINVSS-VAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 A+ + K G VIN+SS V A+ Q+ +P Y ATK AV + + E S G Sbjct: 124 LALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE--SPYG 176 Query: 524 VRVLTVCFGATDTAL 568 VRV + G T L Sbjct: 177 VRVNCISPGNIWTPL 191 >UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular organisms|Rep: Alcohol dehydrogenase - Bordetella parapertussis Length = 252 Score = 70.5 bits (165), Expect = 3e-11 Identities = 52/195 (26%), Positives = 89/195 (45%), Gaps = 5/195 (2%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K +TGA +G GE + EG K + + DI E G+ + +N+ G + F R+DV Sbjct: 6 KTAIVTGAGSGFGEGIAATFAREGAK-VVVADINEAGGQRVAAAINAA-GGQAVFVRADV 63 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 367 ++ +L A ++ GG+D+V+NNA + + + + E + +K+I + Sbjct: 64 SDNAAVANLLAATLKAFGGLDIVVNNAGTTHRNRPML-EVEEDEFDRIYAINVKSIYLTA 122 Query: 368 KH-----SGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532 +H GG+ IN++S AA+ + Y +K AV+ S + V Sbjct: 123 RHMVPHFRAHGGGSFINIASTAAIRPRPGLTWYNGSKGAVVTTSKSMAAELGPDNIRVNC 182 Query: 533 LTVCFGATDTALLTD 577 + GA T LL D Sbjct: 183 VNPVIGA--TGLLAD 195 >UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1; Terrabacter sp. DBF63|Rep: Short-chain dehydrogenase/redutase - Terrabacter sp. DBF63 Length = 252 Score = 70.5 bits (165), Expect = 3e-11 Identities = 54/195 (27%), Positives = 91/195 (46%), Gaps = 7/195 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TG GIG ++L+D G + + + D++E+AG ++ G+ F R+DV Sbjct: 8 KVALVTGGGGGIGRETAKVLVDHGAR-VVVADLSEDAGNGTLEYIDG--GDAVAFVRADV 64 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 346 T+ ++ A V G +D+ NNA L + ++ + K I VN+T + S + Sbjct: 65 TDLASMQHLVQAAVDRYGRLDIAHNNAGIEVTGPDLADVTVEQFDKVIAVNLTGVFIS-M 123 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 KA EI + G GG++IN +S Y +K V+ + +S G+ Sbjct: 124 KA-EIPQMLAQG-GGSIINTASSLGQAALAHQSAYVTSKHGVIGLTRAAA--VEYSDKGI 179 Query: 527 RVLTVCFGATDTALL 571 RV V G T ++ Sbjct: 180 RVNAVLPGVIQTPMI 194 >UniRef50_Q3VZL7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 261 Score = 70.5 bits (165), Expect = 3e-11 Identities = 60/196 (30%), Positives = 91/196 (46%), Gaps = 11/196 (5%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV ITG G G++ L + G H+ + DI + + EL + G+ T DV Sbjct: 18 KVALITGGGRGFGKAFGAALTERGA-HVVLADIDGDVASAAAAELTALGGSATGV-TCDV 75 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI---------GIYKKAIEVNVTALITS 340 T+E ++ +V+ GG+D+++NNA L + + G ++ EVNV ++ Sbjct: 76 TDEARVGEVVADIVRAHGGLDILVNNAGLHSAAFNKPTAELGAGQIRRLFEVNVMGVVIC 135 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 TL A + M SG G V+N+SS AA Y +K AV F+ R + Sbjct: 136 TLAAKDAM---SGRAGAAVVNISSSAAYAN---RTAYGVSKLAVRGFTAQFAR--ELAAV 187 Query: 521 GVRVLTVCFG--ATDT 562 GVRV + G TDT Sbjct: 188 GVRVNAIAPGLILTDT 203 >UniRef50_Q1V2H3 Cluster: Short chain dehydrogenase; n=2; Candidatus Pelagibacter ubique|Rep: Short chain dehydrogenase - Candidatus Pelagibacter ubique HTCC1002 Length = 253 Score = 70.5 bits (165), Expect = 3e-11 Identities = 48/171 (28%), Positives = 82/171 (47%), Gaps = 5/171 (2%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K+K VF+TG +GIG S+V ++G + +DI E+A L +E +K + F + Sbjct: 9 KNKRVFVTGGGSGIGASIVEHFCEQG-SEVYFIDINEKASNKLVLECKNKNFSVPTFIKC 67 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK---- 349 D+ N + ++ ++ G IDV++NNAA ND + E + L+ Sbjct: 68 DLLNIKDLQNTISKIIDNNGAIDVLVNNAA--NDERHSIDEVTEEFWNERMNINLRHYFF 125 Query: 350 AIEIMGKHS-GGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGR 499 ++ + K K G++IN+ SV+ + M Y A KS V+ + R Sbjct: 126 TVQSVKKAMIANKSGSIINIGSVSWMIGQGGMAAYTAAKSGVVGLTRSFAR 176 >UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 286 Score = 70.5 bits (165), Expect = 3e-11 Identities = 48/181 (26%), Positives = 87/181 (48%), Gaps = 6/181 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 + F+TG GIG ++ I L E ++AILDI E + + G + + +DV Sbjct: 10 QAAFVTGGGGGIGRAIA-IRLAEAGANVAILDIIAERAEETATRIRET-GARALTFPADV 67 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLK 349 + ++ G +D+++NNA + S +K I++N+ +++ +T Sbjct: 68 MESDALRAAIDQAAAAFGRLDILVNNAGGVSARPFLEQSERSMRKHIDINLMSMLVATQA 127 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 A M +GGKGG++INV+S+ A + +Y A K+ + F+ + S G+R Sbjct: 128 AARHMV--AGGKGGSIINVASIEATRAAPNFAVYAACKAGMFSFTRSMAL--ELSGHGIR 183 Query: 530 V 532 V Sbjct: 184 V 184 >UniRef50_Q11ZZ1 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Polaromonas sp. JS666|Rep: Short-chain dehydrogenase/reductase SDR - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 265 Score = 70.5 bits (165), Expect = 3e-11 Identities = 56/204 (27%), Positives = 102/204 (50%), Gaps = 7/204 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEE-AGKSLQVELNSKYGNKTKFYR 178 K+K V +TG + IG ++V EG HI I D+ E+ A K+ ++ L S + + + Sbjct: 6 KNKSVIVTGGGSNIGRAIVLGFAAEGA-HITIGDVDEQQAQKTAELALLSGAAS-AQVVK 63 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAA---LM---NDSIGIYKKAIEVNVTALITS 340 +DVT + + A V + GG+DV++NN LM + +++K I +N ++ Sbjct: 64 TDVTQLDQVQAMFKAAVDKFGGVDVLVNNVGWDQLMFFTQTTPDLWQKIIAINYVGVLNC 123 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 T A+++M + G+++++SS A+ +Y K+A+ F + + + Sbjct: 124 TKTALDLMIPRN---AGSIVSISSDASRQGEPREAVYGGVKAAINSFMKTIAKEN--GRY 178 Query: 521 GVRVLTVCFGATDTALLTDEKLGT 592 G+R VC G T + TDE G+ Sbjct: 179 GIRCNVVCPGITIPS-TTDEVGGS 201 >UniRef50_O33454 Cluster: P-cumic alcohol dehydrogenase; n=3; Proteobacteria|Rep: P-cumic alcohol dehydrogenase - Pseudomonas putida Length = 252 Score = 70.5 bits (165), Expect = 3e-11 Identities = 59/194 (30%), Positives = 93/194 (47%), Gaps = 9/194 (4%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 KDKV +TGAATGIG ++VR L EG K + I D+ + ++ EL + + Sbjct: 4 KDKVAIVTGAATGIGNAIVRSYLAEGAK-VVIADV--KGAEAAAAELGE---DLALGVFA 57 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMN-------DSIGI--YKKAIEVNVTALI 334 DV++ + + A + G IDV++NNA + +SI + + K VNV Sbjct: 58 DVSDPDSTKQMAKAALDRFGKIDVLVNNAGIFTGLNYVPMESISVADWDKLYSVNVKG-- 115 Query: 335 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFS 514 L A + G GG +IN++SV A + M Y ++K AV + + R + Sbjct: 116 -PWLCASAVSAAMREGGGGKIINIASVIAHIGAPFMLHYVSSKGAVAAMTRAMAREFATT 174 Query: 515 KTGVRVLTVCFGAT 556 K G+ V ++ G T Sbjct: 175 KAGISVNSISPGYT 188 >UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=1; Marinomonas sp. MED121|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Marinomonas sp. MED121 Length = 259 Score = 70.5 bits (165), Expect = 3e-11 Identities = 57/185 (30%), Positives = 90/185 (48%), Gaps = 6/185 (3%) Frame = +2 Query: 14 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTN 193 V +TG A+GIGE++V+ L +G ++ DI EEAG+ L LNS +G K F D+T+ Sbjct: 20 VLVTGGASGIGEALVKALAQQGCA-VSFFDIDEEAGEQLAQNLNS-HGMKAHFELVDLTD 77 Query: 194 EEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLKAI 355 E + A ++ G I ++NNAA L S + + + VN+ + K Sbjct: 78 IEMLKDKIQARLEAWGAIRALVNNAANDHRHTLAELSSDEFDQCMAVNLKHHFFAAQKVA 137 Query: 356 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535 +M + GG++IN+SS + + P Y K+ + + + R T VRV Sbjct: 138 PLMAE---AGGGSIINMSSNSWMLGLSGYPGYVTAKAGISGLTKALAR--ELGPTKVRVN 192 Query: 536 TVCFG 550 TV G Sbjct: 193 TVLPG 197 >UniRef50_A3JFT9 Cluster: Short chain dehydrogenase; n=1; Marinobacter sp. ELB17|Rep: Short chain dehydrogenase - Marinobacter sp. ELB17 Length = 273 Score = 70.5 bits (165), Expect = 3e-11 Identities = 49/183 (26%), Positives = 94/183 (51%), Gaps = 6/183 (3%) Frame = +2 Query: 14 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTN 193 VFITG A+G+G ++ EG K + I D+ + G ++ E+ SK G + + DV Sbjct: 5 VFITGGASGLGRAIALRYAREGAK-VCIGDVNPQQGALVEQEI-SKAGGEGYYVDCDVRR 62 Query: 194 EEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITSTLKAI 355 + + + + GG+D+V+NNA ++ + + ++ +++NV ++ KA Sbjct: 63 LKDLERVRDDLAARWGGVDIVVNNAGVASAGSIEDTPMADWEWILDINVLGVVRG-CKAF 121 Query: 356 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535 M K G GT +N++S+A L + +M Y +K+ V+ S + + ++G++V Sbjct: 122 TPMFKQQG--AGTFVNIASMAGLMLAPMMNSYNVSKAGVIALSETMS--QELRESGIQVS 177 Query: 536 TVC 544 VC Sbjct: 178 CVC 180 >UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Polaromonas naphthalenivorans (strain CJ2) Length = 286 Score = 70.5 bits (165), Expect = 3e-11 Identities = 57/207 (27%), Positives = 103/207 (49%), Gaps = 11/207 (5%) Frame = +2 Query: 11 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVT 190 V +TGAA GIG + + L +G++ +A+LD+ +A ++ EL S + DVT Sbjct: 21 VAIVTGAADGIGWATAQRLAADGLR-VALLDLRADAAQARAAELGSIHLG----LGCDVT 75 Query: 191 NEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNV--TALITST 343 +EE + AV++ G ID ++NNA + S+ + + + V++ T L++ Sbjct: 76 SEESVEAAVAAVLERFGRIDALVNNAGIGDQTGPTTEQSVQAFDRVLAVHLRGTFLMSRA 135 Query: 344 LKAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 + + G+G G ++N+ S+A+ T Y A K+ VL + + +++ Sbjct: 136 VARHMLQAAPVPGRGRGAIVNLGSIASSTGLPARNAYSAGKAGVLGMTRAMA--SEWARA 193 Query: 521 GVRVLTVCFGATDTALLTD-EKLGTFD 598 G+RV V G TAL+ + E+ G D Sbjct: 194 GIRVNAVAPGYVRTALVAELERKGAID 220 >UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=6; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Paracoccus denitrificans (strain Pd 1222) Length = 253 Score = 70.5 bits (165), Expect = 3e-11 Identities = 51/190 (26%), Positives = 90/190 (47%), Gaps = 7/190 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 KDKVV ITGA GIG + ++ ++EG + + + D +A + + EL G + + Sbjct: 6 KDKVVLITGAGAGIGAATAKLFIEEGAR-VVVADYLGDAAEQVAAEL----GENARAFTV 60 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITST 343 DV+ E +++ V E GG+DV++NNA + ++ I+VN+T + + Sbjct: 61 DVSKAEACKAMVDFTVAEFGGLDVLVNNAGRGSLGTVETQDENDWRSIIDVNLTGVYLCS 120 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQS-HVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 A+ + K GG ++N +S A+ + Y A K V + + F+ Sbjct: 121 KYAVPELRKRG---GGAIVNTASNIAMAMAIRDRAAYVAAKGGVASLTRAMAL--DFAAD 175 Query: 521 GVRVLTVCFG 550 +RV +V G Sbjct: 176 NIRVNSVAPG 185 >UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR; n=7; Gammaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella sp. (strain ANA-3) Length = 253 Score = 70.5 bits (165), Expect = 3e-11 Identities = 59/206 (28%), Positives = 96/206 (46%), Gaps = 8/206 (3%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 +K +TGAA GIG++++R LL EG + +A A+ + +L+V N +K + D Sbjct: 5 NKTAVVTGAAGGIGQAIIRKLLAEGARVVA----ADLSADALKV-FNDFPADKLVTFSVD 59 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITST 343 VT+ + ++ + G +D++INNA L +D I ++ VN + Sbjct: 60 VTDYKQVEAMVKHAADQFGQLDILINNAGIGLAKPLLQHDPINDFEPVTNVNQKGVYHGI 119 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 L + G G ++N SSV A S + Y +K+AV + C + G Sbjct: 120 LAGGRQF--QAQGSRGVILNTSSVYAQIASEMTFTYNVSKAAVDMMTKCAAL--ELAPLG 175 Query: 524 VRVLTVCFGATDTALLTD-EKLGTFD 598 VRV V G DT +L E LG ++ Sbjct: 176 VRVCAVAPGRVDTPMLRQYEALGLWE 201 >UniRef50_P54554 Cluster: Uncharacterized oxidoreductase yqjQ; n=2; Bacillus|Rep: Uncharacterized oxidoreductase yqjQ - Bacillus subtilis Length = 259 Score = 70.5 bits (165), Expect = 3e-11 Identities = 62/214 (28%), Positives = 105/214 (49%), Gaps = 7/214 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K ++ITGA+ G+GE + + EG H+ + E+ ++ ++ ++ + + + DV Sbjct: 7 KRIWITGASGGLGERIAYLCAAEGA-HVLLSARREDRLIEIKRKITEEWSGQCEIFPLDV 65 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLK 349 E + + + G IDV+INNA +++ ++ K +VNV LI T Sbjct: 66 GRLEDIARVRDQI----GSIDVLINNAGFGIFETVLDSTLDDMKAMFDVNVFGLIACTKA 121 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 + M + K G +IN++S A + +Y ATK AVL +SN + R E S TG+ Sbjct: 122 VLPQMLEQ---KKGHIINIASQAGKIATPKSSLYSATKHAVLGYSNAL-RME-LSGTGIY 176 Query: 530 VLTVCFGATDTALLT-DEKLGTFDKYLEFFMLGP 628 V TV G T + +K G + K + +ML P Sbjct: 177 VTTVNPGPIQTDFFSIADKGGDYAKNVGRWMLDP 210 >UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3; Clostridium|Rep: Bile acid 7-dehydroxylase 1/3 - Eubacterium sp. (strain VPI 12708) Length = 249 Score = 70.5 bits (165), Expect = 3e-11 Identities = 49/194 (25%), Positives = 92/194 (47%), Gaps = 7/194 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-YR 178 +DK+ ITG GIG + ++ ++ G K ++I +E + +L Y + + Sbjct: 5 QDKITIITGGTRGIGFAAAKLFIENGAK-VSIFGETQEEVDTALAQLKELYPEEEVLGFA 63 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 340 D+T+ + + + V Q+ G +DV+INNA + +S+ +K +++NV + Sbjct: 64 PDLTSRDAVMAAVGTVAQKYGRLDVMINNAGITMNSVFSRVSEEDFKNIMDINVNGVFNG 123 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 A + M K G +IN +SV + S Y +K+ V+ ++ +GR + Sbjct: 124 AWSAYQCM---KDAKQGVIINTASVTGIYGSLSGIGYPTSKAGVIGLTHGLGR--EIIRK 178 Query: 521 GVRVLTVCFGATDT 562 +RV+ V G DT Sbjct: 179 NIRVVGVAPGVVDT 192 >UniRef50_Q9C826 Cluster: Xanthoxin dehydrogenase; n=41; Magnoliophyta|Rep: Xanthoxin dehydrogenase - Arabidopsis thaliana (Mouse-ear cress) Length = 285 Score = 70.5 bits (165), Expect = 3e-11 Identities = 58/196 (29%), Positives = 90/196 (45%), Gaps = 9/196 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY-RSD 184 KV ITG ATGIGES+VR+ G K + I+D+ ++ G + L +T F+ D Sbjct: 21 KVALITGGATGIGESIVRLFHKHGAK-VCIVDLQDDLGGEVCKSLLRGESKETAFFIHGD 79 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAAL--------MNDSIGIYKKAIEVNVTALITS 340 V E+ ++ V+ G +D++INNA L N S+ ++ +VNV S Sbjct: 80 VRVEDDISNAVDFAVKNFGTLDILINNAGLCGAPCPDIRNYSLSEFEMTFDVNVKGAFLS 139 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 A +M K G+++++ SV + Y +K AVL + V + Sbjct: 140 MKHAARVMIPE---KKGSIVSLCSVGGVVGGVGPHSYVGSKHAVLGLTRSVA--AELGQH 194 Query: 521 GVRVLTVCFGATDTAL 568 G+RV V A T L Sbjct: 195 GIRVNCVSPYAVATKL 210 >UniRef50_Q8EQ60 Cluster: Oxidoreductase; n=1; Oceanobacillus iheyensis|Rep: Oxidoreductase - Oceanobacillus iheyensis Length = 267 Score = 70.1 bits (164), Expect = 4e-11 Identities = 59/217 (27%), Positives = 110/217 (50%), Gaps = 7/217 (3%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 +K + ITGA++GIGE + + + +G I + ++ ++Q E++ Y ++ Y D Sbjct: 9 NKKIIITGASSGIGEMLAKKVASQGGFPILVARSRDKL-ITIQKEIDQLYNQRSAIYPID 67 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGIYK-----KAIEVNVTALITSTL 346 +T++++ ++ A++ + ID +INNA L + DSI + ++NV A I + Sbjct: 68 LTDKDNIDNLIPAIINDNKQIDALINNAGLGVFDSIEDMNYDDLLETFQLNVFAGIQLSQ 127 Query: 347 KAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 I + K + ++NV S AA + Y ++K A+L F+N V R E + + Sbjct: 128 SIIPYLRKTNANT--QIVNVISQAAKISTPKSASYASSKQAMLGFTN-VLRME-CRMSSI 183 Query: 527 RVLTVCFGATDTALL-TDEKLGTFDKYLEFFMLGPTK 634 V+ V G T +K GT+ + +E +ML P + Sbjct: 184 HVMAVNLGPVRTNFFERADKDGTYKQNVEKYMLDPER 220 >UniRef50_Q88SD1 Cluster: Short-chain dehydrogenase/oxidoreductase; n=4; Bacteria|Rep: Short-chain dehydrogenase/oxidoreductase - Lactobacillus plantarum Length = 279 Score = 70.1 bits (164), Expect = 4e-11 Identities = 50/168 (29%), Positives = 84/168 (50%), Gaps = 8/168 (4%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 DKVV ITGA G+G +G K I ++D+ + ++ +L KYG +T + + Sbjct: 10 DKVVAITGAVGGMGTKFCEEFAKQGAK-IVLIDMIADKTEAYAKKLTEKYGVETLAVKCN 68 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTA--LITS 340 TNEE + AV + G +DV++N AA++ S + ++ A+ VN+T L++ Sbjct: 69 TTNEEEVDAAVKAVTDKFGEVDVLVNTAAILRFSPLEDLRLDEWQAALNVNLTGYFLMSQ 128 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 484 + I KH G ++++S+VA+ Y TK+AV S Sbjct: 129 RFGRVMIQQKH-----GAMVHISTVASRYPETYSGAYSTTKAAVNMMS 171 >UniRef50_Q11E37 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Mesorhizobium sp. BNC1|Rep: Short-chain dehydrogenase/reductase SDR - Mesorhizobium sp. (strain BNC1) Length = 260 Score = 70.1 bits (164), Expect = 4e-11 Identities = 57/197 (28%), Positives = 93/197 (47%), Gaps = 8/197 (4%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 +K+ FITGAA GIG + EG K + + DI E+ G+ + ++ S G F R D Sbjct: 5 NKIAFITGAAEGIGACAAGLFSREGAK-VILSDIDEDRGRKVADQVTSA-GGDAVFVRCD 62 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAA--------LMNDSIGIYKKAIEVNVTALITS 340 VT+E AV + G + ++ NN + + + + A+++NV +++ Sbjct: 63 VTSEASVREAAAAVQERYGALHILYNNVGGSTPRDDRVTDVDLEEFWSAMKLNVLSVVLP 122 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 I ++ SG GG+VIN +S AL + Y A+K AV+ + + F Sbjct: 123 ARHLIPLIAA-SG--GGSVINTASYMALLGTAGRDCYTASKGAVVSLTRSMA--VEFGPD 177 Query: 521 GVRVLTVCFGATDTALL 571 +RV + GA DT L Sbjct: 178 NIRVNVIGPGAVDTERL 194 >UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Enterobacter sp. 638|Rep: Short-chain dehydrogenase/reductase SDR precursor - Enterobacter sp. 638 Length = 242 Score = 70.1 bits (164), Expect = 4e-11 Identities = 56/195 (28%), Positives = 97/195 (49%), Gaps = 6/195 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K +V +TGA++GIGE++ R L G++ + + E + V L S+ G+ ++ Sbjct: 6 KKRVAVVTGASSGIGEALARELAGNGIQVVLLARRFER----IDV-LASELGHGAIAIKA 60 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITST 343 DVT+ E + N V Q GG+D++INNA +M + + +++ +E N+ +T T Sbjct: 61 DVTDRESIVAAANQVEQTLGGVDILINNAGVMLTGPFDSSQLDEHRQMVETNLLGAMTVT 120 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 E+ G ++N+SSVA +Y ATK + +S + R E + Sbjct: 121 ----EVFLPQLRRNKGDLVNISSVAGRVAPSGFAVYAATKWGINGWSEAL-RVE--LQPD 173 Query: 524 VRVLTVCFGATDTAL 568 +RV+ + GA T L Sbjct: 174 IRVMVIEPGAIATEL 188 >UniRef50_A4B8L3 Cluster: Short chain dehydrogenase; n=1; Alteromonas macleodii 'Deep ecotype'|Rep: Short chain dehydrogenase - Alteromonas macleodii 'Deep ecotype' Length = 276 Score = 70.1 bits (164), Expect = 4e-11 Identities = 52/168 (30%), Positives = 83/168 (49%), Gaps = 11/168 (6%) Frame = +2 Query: 14 VFITGAATGIGESVVRILLD-----EGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 178 V ITG ATG+G+++ + EG I I DI +E G L ++ G K + Sbjct: 3 VLITGGATGLGQAIAFKWAEKWKGKEGGIEICIADINQERGDETVNTLTTQ-GAKAFYVY 61 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITS 340 D+T++ + + GGID V NNA +L++++I ++ ++NV ++ Sbjct: 62 CDITSDSDVETLAQTIEARWGGIDTVFNNAGVATGGSLLDETIDQWQWVFDINVLGMVRV 121 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 484 + + IM K GG IN++S A LT M Y A K+AV+ FS Sbjct: 122 SRALLPIMRKQG---GGYFINIASQAGLTPIPYMGSYNAVKAAVVSFS 166 >UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=1; Flavobacteriales bacterium HTCC2170|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Flavobacteriales bacterium HTCC2170 Length = 245 Score = 70.1 bits (164), Expect = 4e-11 Identities = 52/196 (26%), Positives = 93/196 (47%), Gaps = 6/196 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 KDK+ +TG A GIG++V + EG + I+D+ + G+++ + + G K +++ Sbjct: 4 KDKIAVVTGGARGIGQAVSELFAKEGAT-VIIMDLLPQ-GQAVAEGIIAS-GGKAEYHSL 60 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITST 343 VTN+ G+ ++V + G ID++INNA + D S + IEVN+ + T Sbjct: 61 SVTNKSDVEGVFSSVNDKYGKIDILINNAGITRDRTLEKMSEAEWDAVIEVNLKGVFICT 120 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 + M K G +++ +S L + Y ATK+ V+ + F K G Sbjct: 121 QAVVPYM---KASKYGRIVSAASNVGLRGNFGQTNYAATKAGVIAMAKT--WTVEFGKYG 175 Query: 524 VRVLTVCFGATDTALL 571 + + G T T ++ Sbjct: 176 ITANAIAPGFTMTDMV 191 >UniRef50_A2TZ19 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family protein; n=3; Bacteroidetes|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family protein - Polaribacter dokdonensis MED152 Length = 257 Score = 70.1 bits (164), Expect = 4e-11 Identities = 62/223 (27%), Positives = 111/223 (49%), Gaps = 13/223 (5%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV ITG++ GIG+++ + L ++G + + I +EA + E + G T + Sbjct: 12 KVAVITGSSKGIGKAIAKGLAEQGAQ-VVISSRNQEACDEVAKEFKEQ-GLDTIGIACHI 69 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG--------IYKKAIEVNVTALITST 343 E+ +++ ++ G ID+++NNAA+ N G I+ K ++VNV A + Sbjct: 70 GKEDQRKNLVDKTIESFGRIDILVNNAAI-NPVFGPIEEVSPEIFDKIMDVNVKA--PWS 126 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 L + ++ K G++IN++SV ALT + IY +K+A+L + + + + K G Sbjct: 127 LSNL-VLPHFQTNKNGSIINIASVEALTPGLGLGIYSTSKAAILMLTK--NQAKEWGKYG 183 Query: 524 VRVLTVCFGATDT----ALLTDEK-LGTFDKYLEFFMLGPTKE 637 V+ +C G T AL +EK L +K L +G +E Sbjct: 184 VKANAICPGLIKTKFSAALWQNEKILSKVEKALPSSRMGMPEE 226 >UniRef50_Q965D6 Cluster: 3-oxoacyl-acyl-carrier protein reductase precursor; n=8; Plasmodium|Rep: 3-oxoacyl-acyl-carrier protein reductase precursor - Plasmodium falciparum Length = 301 Score = 70.1 bits (164), Expect = 4e-11 Identities = 42/169 (24%), Positives = 88/169 (52%), Gaps = 3/169 (1%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 ++KV +TGA GIG + + +L + V H+ + +++ S+ E+ S +G ++ Y Sbjct: 59 ENKVALVTGAGRGIGREIAK-MLAKSVSHVICISRTQKSCDSVVDEIKS-FGYESSGYAG 116 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE---VNVTALITSTLKA 352 DV+ +E ++N ++ E +D++++NA + D++ + K E V T L + Sbjct: 117 DVSKKEEISEVINKILTEHKNVDILVSNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYIT 176 Query: 353 IEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGR 499 I + + G +IN+SS+ LT + Y ++K+ V+ F+ + + Sbjct: 177 QPISKRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAK 225 >UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59; cellular organisms|Rep: Acetoin(diacetyl) reductase - Klebsiella pneumoniae Length = 256 Score = 70.1 bits (164), Expect = 4e-11 Identities = 53/193 (27%), Positives = 88/193 (45%), Gaps = 6/193 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TGA GIG+++ L+ +G +AI D + K++ E+N G + + DV Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFA-VAIADYNDATAKAVASEINQA-GGRAMAVKVDV 60 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMN----DSI--GIYKKAIEVNVTALITSTLK 349 ++ + + + GG DV++NNA + +SI I K +NV +I Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQA 120 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 A+E K G GG +IN S A + + +Y ++K AV + R + G+ Sbjct: 121 AVEAFKKE--GHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAAR--DLAPLGIT 176 Query: 530 VLTVCFGATDTAL 568 V C G T + Sbjct: 177 VNGYCPGIVKTPM 189 >UniRef50_Q81WX9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reductase, putative; n=10; Bacillus cereus group|Rep: 3-oxoacyl-(Acyl-carrier-protein) reductase, putative - Bacillus anthracis Length = 246 Score = 69.7 bits (163), Expect = 5e-11 Identities = 50/192 (26%), Positives = 94/192 (48%), Gaps = 7/192 (3%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K +TGAA GIG+ + R+ G K + I D+ EE + EL + G + YR DV Sbjct: 7 KTAVVTGAAQGIGKEIARVYAKLGAK-VLISDVNEEKLQKTTRELLDE-GYEVSLYRCDV 64 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITSTLK 349 +N+ ++ VQ+ G + +++NNA + D++ +++ ++VN+T + Sbjct: 65 SNQNEAKSLIEYAVQKFGTLHILVNNAGITRDAMLHKMEKSSWEQVLQVNLTGVFYCMQP 124 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHV-MPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 A+ M + G+ +IN+SS++ + ++ Y ATK+ V+ + + G+ Sbjct: 125 ALLYMRQQGYGR---IINISSIS--REGNIGQANYAATKAGVVGLTKTAAK--EVGSFGI 177 Query: 527 RVLTVCFGATDT 562 +C G DT Sbjct: 178 TCNAICPGFMDT 189 >UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia succiniciproducens MBEL55E|Rep: FabG protein - Mannheimia succiniciproducens (strain MBEL55E) Length = 248 Score = 69.7 bits (163), Expect = 5e-11 Identities = 54/195 (27%), Positives = 93/195 (47%), Gaps = 6/195 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 + K +TGA TGIG+++ L EG K + + K+LQ E + + N + + Sbjct: 5 EQKTALVTGAGTGIGQAIAVRLAQEGAKVL----VVGRTEKTLQ-ETTALHPN-IAYAVA 58 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 343 D+ ++ I+ + Q+ GG+D++INNA + I Y K +NV AL+ T Sbjct: 59 DIEKDDDVQKIVQQLNQKYGGLDILINNAGWAPVTPISQVKIEEYDKVFGINVRALVNLT 118 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 L+ + ++ + G +IN+SS M +Y TK+AV F+ + G Sbjct: 119 LQCLPML----KARKGNIINMSSAICRNHLPNMSMYAGTKAAVEIFTKIWAK--ELGADG 172 Query: 524 VRVLTVCFGATDTAL 568 VRV ++ G +T + Sbjct: 173 VRVNSISVGPIETPI 187 >UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxidoreductase - Geobacillus kaustophilus Length = 260 Score = 69.7 bits (163), Expect = 5e-11 Identities = 62/218 (28%), Positives = 106/218 (48%), Gaps = 12/218 (5%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K +TG G+GE + L + G ++ + EA + ++ +L + G ++ R DV Sbjct: 12 KTAIVTGGGRGLGEQIAVGLAEAGA-NVVVCSRKVEACEQVKEKLE-QLGVRSLALRCDV 69 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINN------AALMNDSIGIYKKAIEVNVTALITSTLK 349 TN E ++ V+E GGID+++NN A + + ++K I VNVT + Sbjct: 70 TNPEEVKHVVETTVKEFGGIDILVNNSGATWGAPVEEMPLEAWQKVINVNVTGTFLMSQA 129 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPI----YFATKSAVLQFSNCVGRPEHFSK 517 ++M + GG++IN++SVA L +H + Y +K AV+ F+ + + K Sbjct: 130 VGKVM--IAKQTGGSIINIASVAGLGGTHPDILNTIGYNTSKGAVITFTRDLA--AKWGK 185 Query: 518 TGVRVLTVC--FGATDTALLTDEKLGTFDKYLEFFMLG 625 G+RV V F T + + E++G K LE LG Sbjct: 186 HGIRVNAVAPGFFPTKMSKVVLERVG--KKVLEHTPLG 221 >UniRef50_Q39TR6 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Geobacter|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 255 Score = 69.7 bits (163), Expect = 5e-11 Identities = 54/193 (27%), Positives = 91/193 (47%), Gaps = 9/193 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV ITG A GIG + L EG K I I D+ + A VE G+ + ++DV Sbjct: 7 KVAIITGGAQGIGAAYAVGLAKEGAK-IVIADVLDGAKA---VEAVKAAGSDAIYVKTDV 62 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI---------GIYKKAIEVNVTALITS 340 +++E + A ++ G +D+++NNAA+ + + K +E+NV + Sbjct: 63 SSQEQCDAMAQAAAEKFGSVDILLNNAAIFGSIVLKPFTECTPQEFMKVMEINVLGQF-N 121 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 +KA+ H +GG +IN+SS + + MP Y A+K A++ + + R K Sbjct: 122 CMKAV---FPHMKARGGKIINISSSSIIEGVPGMPHYVASKGAIMALTRSMARELGDYKI 178 Query: 521 GVRVLTVCFGATD 559 V + F +D Sbjct: 179 NVNTIAPGFTHSD 191 >UniRef50_A6EZZ8 Cluster: Short chain dehydrogenase; n=1; Marinobacter algicola DG893|Rep: Short chain dehydrogenase - Marinobacter algicola DG893 Length = 252 Score = 69.7 bits (163), Expect = 5e-11 Identities = 53/166 (31%), Positives = 83/166 (50%), Gaps = 7/166 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 KV +TGA IGE V R+L EG IA++D+ + + ++ + G + K + DV Sbjct: 6 KVAIVTGAGRNIGEEVSRVLSAEGAT-IAVVDLDRSRAEKVAADIVAS-GGQAKPFICDV 63 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-KAIEVNVTALITSTLK----- 349 +E+ + AVV + GG+D+++NN A M+D+ I+ A E N T IT T Sbjct: 64 ASEDQIRATVAAVVDQLGGLDILVNNVA-MSDNKHIFDITAEEWNRTLAITLTAPFLFGK 122 Query: 350 -AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFS 484 A + M +H+ G +INVSS + Y A K V+ + Sbjct: 123 YAAQAMVQHAA--DGRIINVSSTSGYYGRDRAIAYTAAKGGVINLT 166 >UniRef50_A5WHV5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Psychrobacter sp. PRwf-1|Rep: Short-chain dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1 Length = 273 Score = 69.7 bits (163), Expect = 5e-11 Identities = 58/198 (29%), Positives = 96/198 (48%), Gaps = 10/198 (5%) Frame = +2 Query: 20 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKY---GNKTKFYRSDVT 190 +TGAA+GIG ++ LL + + DI EA Q+ N K G + DV Sbjct: 7 VTGAASGIGRALCERLLTDKGNQVCACDINYEA--LTQIYANHKLADAGGSLILRQLDVR 64 Query: 191 NEEHFLGILNAVVQEQGGIDVVINNAALMNDS----IGIYKKA---IEVNVTALITSTLK 349 + + + ++N V+ + IDV+ N A ++ D+ I + ++NV I T Sbjct: 65 DVQQWQEVVNTVIAQWQRIDVMCNIAGVLKDNWIADIALPDDVDLHFDINVKGTIFGTQS 124 Query: 350 AIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVR 529 ++ M ++ G G +INV+S+AAL+ + +Y A+K AV +S G K G+ Sbjct: 125 VVDTM-RNQGS--GHIINVASLAALSPVPGLSLYSASKYAVRAYSLAAGM--ELEKYGIA 179 Query: 530 VLTVCFGATDTALLTDEK 583 V T+C A T +L +K Sbjct: 180 VTTLCPDAVQTPMLDQQK 197 >UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Stappia aggregata IAM 12614|Rep: Short-chain dehydrogenase/reductase SDR - Stappia aggregata IAM 12614 Length = 270 Score = 69.7 bits (163), Expect = 5e-11 Identities = 53/200 (26%), Positives = 95/200 (47%), Gaps = 8/200 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 +V +TGA+ GIGE+ R L G K + + +++ + + E+ ++ G DV Sbjct: 24 QVALVTGASRGIGEAAARSLAKYGAK-VVLAARSDKDIERIAGEIRAE-GQDATAVVCDV 81 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 346 + + + + V GG+D+++NNA ++ I + K I++NV + Sbjct: 82 ADYDDVVKAVQTAVDTYGGLDILVNNAGVIEPIARIEDSDPAEWGKVIDINVKGVYYG-- 139 Query: 347 KAIEIMGKHSGGKG-GTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 + KH KG GTV+N+SS AA++ Y A+K+A L + C + F G Sbjct: 140 --LHAAAKHMLAKGAGTVVNISSGAAVSALEGWSHYCASKAAALSLTRCADK--EFGDKG 195 Query: 524 VRVLTVCFGATDTALLTDEK 583 +R++ + G T + D K Sbjct: 196 LRIVGLSPGTVATQMQVDIK 215 >UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Shewanella woodyi ATCC 51908|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella woodyi ATCC 51908 Length = 255 Score = 69.7 bits (163), Expect = 5e-11 Identities = 49/191 (25%), Positives = 94/191 (49%), Gaps = 6/191 (3%) Frame = +2 Query: 14 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTN 193 VFITG A+GIG ++VR +++G ++ +D +AG++L L+ G + F+ DVT+ Sbjct: 15 VFITGGASGIGAALVRAFVEQGA-NVTFVDTNRDAGEALLQGLDINRGQQVAFHLLDVTD 73 Query: 194 EEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGI----YKKAIEVNVTALITSTLKAI 355 + ++ Q+ G +D++INN +D+ G+ +K+ + +N+ + ++ A Sbjct: 74 TKQLQQMITEQDQKLGQLDILINNVGNDSRHDADGVDEHEWKQCMAINLDSAFFASQAAY 133 Query: 356 EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRVL 535 +M + K G +IN SS A M Y K+ + + + + S+ V + Sbjct: 134 LVMKQR---KQGVIINFSSNMAYIGERNMAGYITAKAGIAGMTKALAKDYGESRVRVNAI 190 Query: 536 TVCFGATDTAL 568 + AT L Sbjct: 191 VPGWVATQRQL 201 >UniRef50_O15744 Cluster: PksB; n=2; Dictyostelium discoideum|Rep: PksB - Dictyostelium discoideum (Slime mold) Length = 260 Score = 69.7 bits (163), Expect = 5e-11 Identities = 61/205 (29%), Positives = 100/205 (48%), Gaps = 6/205 (2%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVEL-NSKYGNKTKFYRS 181 +K+V ITGA++GIGES +I G HI + + L+ +L + G K + Sbjct: 7 NKIVLITGASSGIGESCAKIFHQNG-NHIILCGRRVDRLNKLRDQLIANNSGGKVLACQV 65 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI-- 355 DV++ E ++N + ++ ID++INNA L + + + ++ ++I + +K + Sbjct: 66 DVSSMESIDKMINELPEDMKSIDILINNAGLSLGMDSVSEIDAKNDLDSVIDTNVKGVFR 125 Query: 356 ---EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGV 526 +I+ G + NVSS+A IY A+K+AV FS+ V R E S T + Sbjct: 126 VTRKILPNMIQRNSGYIFNVSSIAGSMFYPNGSIYCASKAAVNAFSD-VLRKEVVS-TKI 183 Query: 527 RVLTVCFGATDTALLTDEKLGTFDK 601 RV VC G +T G DK Sbjct: 184 RVTNVCPGLVETEFSLVRFNGDADK 208 >UniRef50_Q92EK7 Cluster: Uncharacterized oxidoreductase Lin0452; n=30; Bacteria|Rep: Uncharacterized oxidoreductase Lin0452 - Listeria innocua Length = 248 Score = 69.7 bits (163), Expect = 5e-11 Identities = 55/193 (28%), Positives = 89/193 (46%), Gaps = 3/193 (1%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K+KV+ ITGA++GIGE+ +L ++G K + E+ K +Q + + G + F ++ Sbjct: 4 KNKVIIITGASSGIGEATAILLAEKGAKLVLAARRVEKLEKIVQT-IKASSG-EAIFAKT 61 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALM-NDSIGIYKK-AIEVNVTALITSTLKAI 355 DVT E ++ ++ G +D + NA +M N + K+ E + I L I Sbjct: 62 DVTKREDNKKLVELAIERYGKVDAIFLNAGIMPNSPLSALKEDEWEQMIDINIKGVLNGI 121 Query: 356 -EIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTGVRV 532 ++ K G +I SSVA L +Y ATK AV + T +R Sbjct: 122 AAVLPSFIAQKSGHIIATSSVAGLKAYPGGAVYGATKWAVRDLMEVLRMESAQEGTNIRT 181 Query: 533 LTVCFGATDTALL 571 T+ A +T LL Sbjct: 182 ATIYPAAINTELL 194 >UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2; Streptomyces|Rep: Putative dehydrogenase - Streptomyces coelicolor Length = 255 Score = 69.3 bits (162), Expect = 7e-11 Identities = 55/195 (28%), Positives = 89/195 (45%), Gaps = 8/195 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 187 K +TGA +GIG +V L EG H+ + A L + G K +DV Sbjct: 9 KTALVTGAGSGIGRAVALALAAEGA-HVVVAGRAR-GPLDETAALVEQAGGKALAVTADV 66 Query: 188 TNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 346 T E +++A V+ G +DV +NNA + + + + +++NVT + + Sbjct: 67 TRREDVDALVSAAVEHFGSLDVAVNNAGVFRGGVPVADLSEEDWHTQLDINVTGVFLALR 126 Query: 347 KAIEIMGKHSGGKGGTVINVSSV-AALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 + M G GGT++N++S A +S Y ATK+AV + +H G Sbjct: 127 AEVRHMRAQPG--GGTIVNIASTFGAHKRSPGATAYAATKAAVSALTRGAAL-DHIG-DG 182 Query: 524 VRVLTVCFGATDTAL 568 VR+ V GAT T++ Sbjct: 183 VRINAVSPGATATSM 197 >UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|Rep: Bll5898 protein - Bradyrhizobium japonicum Length = 256 Score = 69.3 bits (162), Expect = 7e-11 Identities = 60/196 (30%), Positives = 90/196 (45%), Gaps = 7/196 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR- 178 KDKVV +TGA +GIG + R EG I +L+ E S E+ ++ G R Sbjct: 6 KDKVVIVTGAGSGIGAAAARRFHGEGA--IVVLNGRRE---SKLAEVGAELGTDRCMIRP 60 Query: 179 SDVTNEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITS 340 +DVT ++ V+ G ID+++NNA + I ++ VNV ++ Sbjct: 61 ADVTIAADVESLVADAVRRFGRIDILVNNAGTGALIDFLGSPIQQWRDLFAVNVDGVLYM 120 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 T A+ H GG+++NVSS++ L + Y ATK AV + + F Sbjct: 121 TRAAL----PHLIESGGSIVNVSSLSGLGGDRGLSFYNATKGAVSNLTRSLAL--EFGPR 174 Query: 521 GVRVLTVCFGATDTAL 568 GVR+ VC T T L Sbjct: 175 GVRINAVCPSLTLTHL 190 >UniRef50_Q5LMX2 Cluster: 20-beta-hydroxysteroid dehydrogenase, putative; n=25; Alphaproteobacteria|Rep: 20-beta-hydroxysteroid dehydrogenase, putative - Silicibacter pomeroyi Length = 250 Score = 69.3 bits (162), Expect = 7e-11 Identities = 57/202 (28%), Positives = 93/202 (46%), Gaps = 8/202 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 K K V ITGA+ GIG R+ G ++ +L + EA + E+ G++ Sbjct: 5 KGKTVLITGASRGIGAEAGRVFAQAGA-NVVLLARSAEALAAQAAEI----GDRALALAC 59 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALM--------NDSIGIYKKAIEVNVTALIT 337 DV + G +NA V GG+DV+INNA ++ +D +G + AI++N+ + Sbjct: 60 DVADAAQVAGAVNAAVSRFGGLDVLINNAGVIEPISHLASSDPVG-WGHAIDINLKGVYY 118 Query: 338 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSK 517 A+ +M K GGT++ VSS AA Y A+K+ + C+ E Sbjct: 119 GMRAALPVMRK---AGGGTILTVSSGAAHNPVEAWSHYCASKAGAAMLTACLHLEE--GH 173 Query: 518 TGVRVLTVCFGATDTALLTDEK 583 G+R + + G T + + K Sbjct: 174 HGIRAMGLSPGTVATQMQREIK 195 >UniRef50_Q3M1E6 Cluster: NAD-dependent epimerase/dehydratase precursor; n=3; Cyanobacteria|Rep: NAD-dependent epimerase/dehydratase precursor - Anabaena variabilis (strain ATCC 29413 / PCC 7937) Length = 251 Score = 69.3 bits (162), Expect = 7e-11 Identities = 51/194 (26%), Positives = 90/194 (46%), Gaps = 7/194 (3%) Frame = +2 Query: 2 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 181 KDKV +TG +GIG + + K + + +E ++ V L + G + F +S Sbjct: 4 KDKVALVTGGTSGIGRATAIAYAKQQAKVVVVGRRIDEGEET--VRLIQEAGGEAFFVQS 61 Query: 182 DVTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 340 DVT E +++ V G +D+ NNA ++ ++ + Y + + VNV + S Sbjct: 62 DVTKEADVKAMVDKAVGVFGRLDIAFNNAGMVGENPSLIEQTEAEYDRIMNVNVKGVWLS 121 Query: 341 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKT 520 I M K G ++N SS A + +P+Y A+K AV+ + ++K Sbjct: 122 MKYEIAQMLKQG---SGAIVNTSSGAGVVALPGVPLYTASKHAVVGLTKAAAL--QYAKA 176 Query: 521 GVRVLTVCFGATDT 562 G+R+ V G+ +T Sbjct: 177 GIRINAVAPGSIET 190 >UniRef50_Q3WGS3 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 306 Score = 69.3 bits (162), Expect = 7e-11 Identities = 58/193 (30%), Positives = 88/193 (45%), Gaps = 8/193 (4%) Frame = +2 Query: 8 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSK-YGNKTKFYRSD 184 KV ITGA +GIG S + EG + + A+ +G+ L +K G+ D Sbjct: 67 KVAVITGAGSGIGRSAAFLFAREGARVVC----ADVSGREA---LTAKAVGDGAIAVHVD 119 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITST 343 VT+ E ++ V G +DV+ NNA + + + + VNV + Sbjct: 120 VTSTEDIERMITTAVDRFGKLDVLYNNAGFTGPIVPLAEAGEDYFDAVMAVNVKGVYLGM 179 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMPIYFATKSAVLQFSNCVGRPEHFSKTG 523 AI +M G GG++IN +S A L + +Y ATK AV+Q + ++ G Sbjct: 180 KAAIPVM---LAGGGGSIINTASAAGLVGWKGLAVYAATKGAVVQLTRSAAL--DYAAKG 234 Query: 524 VRVLTVCFGATDT 562 +RV VC GAT T Sbjct: 235 IRVNAVCPGATWT 247 >UniRef50_A6EGH2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=1; Pedobacter sp. BAL39|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Pedobacter sp. BAL39 Length = 248 Score = 69.3 bits (162), Expect = 7e-11 Identities = 55/198 (27%), Positives = 95/198 (47%), Gaps = 9/198 (4%) Frame = +2 Query: 5 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 184 +KV ITGAA G+GES R + EG K + + D++ EAG+ L EL G F + D Sbjct: 6 NKVAIITGAAQGMGESHARTFVAEGAK-VILTDVSAEAGQKLADEL----GENAIFIKHD 60 Query: 185 VTNEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITST 343 VT E + ++ + G ++V++NNA ++ + Y K ++N ++ Sbjct: 61 VTCSEQWAHVVAEAEKAFGHVNVLVNNAGILGPMVKTQELQEADYLKVCDINQHSVFYGM 120 Query: 344 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVMP--IYFATKSAVLQFSNCVGRPEHFSK 517 I M K G+++N+SS+A + ++ P Y A+K AV + + + Sbjct: 121 KAVIPSMIK---AGIGSIVNISSIAGIVANYGFPSLAYVASKFAVRGMTKATA--IEYGE 175 Query: 518 TGVRVLTVCFGATDTALL 571 +RV +V G T ++ Sbjct: 176 KNIRVNSVHPGFIKTPMM 193 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 618,708,219 Number of Sequences: 1657284 Number of extensions: 12277825 Number of successful extensions: 43153 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 39075 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 40684 length of database: 575,637,011 effective HSP length: 97 effective length of database: 414,880,463 effective search space used: 47711253245 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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