BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= maV30017 (462 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q6NYE8 Cluster: Zgc:56585 protein; n=5; Clupeocephala|R... 125 4e-28 UniRef50_Q1G151 Cluster: Putative alcohol dehydrogenase; n=1; Bo... 118 6e-26 UniRef50_UPI0000DB7440 Cluster: PREDICTED: similar to 15-hydroxy... 110 1e-23 UniRef50_UPI00015B573D Cluster: PREDICTED: similar to putative a... 108 7e-23 UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative a... 107 2e-22 UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative a... 105 5e-22 UniRef50_Q6RUR3 Cluster: Putative alcohol dehydrogenase; n=2; Ne... 104 8e-22 UniRef50_UPI0000513348 Cluster: PREDICTED: similar to 15-hydroxy... 101 6e-21 UniRef50_UPI0000E47587 Cluster: PREDICTED: similar to 15-hydroxy... 100 2e-20 UniRef50_UPI00015B5316 Cluster: PREDICTED: similar to putative a... 99 2e-20 UniRef50_UPI00015B4C63 Cluster: PREDICTED: similar to putative a... 98 7e-20 UniRef50_UPI00015B42E2 Cluster: PREDICTED: similar to putative a... 96 3e-19 UniRef50_UPI000051334A Cluster: PREDICTED: similar to 15-hydroxy... 96 4e-19 UniRef50_P15428 Cluster: 15-hydroxyprostaglandin dehydrogenase [... 95 9e-19 UniRef50_UPI00015B5FC8 Cluster: PREDICTED: similar to putative a... 93 4e-18 UniRef50_Q7PY55 Cluster: ENSANGP00000013280; n=4; Endopterygota|... 91 1e-17 UniRef50_A6YPS8 Cluster: Oxidoreductase; n=1; Triatoma infestans... 89 6e-17 UniRef50_UPI0000D57364 Cluster: PREDICTED: similar to 15-hydroxy... 88 1e-16 UniRef50_UPI00015B5A58 Cluster: PREDICTED: similar to putative a... 87 1e-16 UniRef50_UPI0000D57365 Cluster: PREDICTED: similar to CG4899-PA,... 87 2e-16 UniRef50_Q5P8S6 Cluster: Putative dehydrogenase; n=4; Proteobact... 84 2e-15 UniRef50_Q9ABI1 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 83 2e-15 UniRef50_Q1HPX6 Cluster: Alcohol dehydrogenase; n=1; Bombyx mori... 83 3e-15 UniRef50_Q6C6W8 Cluster: Similar to tr|Q9WYD3 Thermotoga maritim... 83 3e-15 UniRef50_UPI00015B572C Cluster: PREDICTED: similar to putative a... 81 1e-14 UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative a... 80 2e-14 UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|R... 80 3e-14 UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 79 4e-14 UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to hydroxypro... 79 5e-14 UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1; ... 78 8e-14 UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR... 77 2e-13 UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reducta... 76 4e-13 UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR... 75 6e-13 UniRef50_UPI0000D5767E Cluster: PREDICTED: similar to 15-hydroxy... 75 8e-13 UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase fam... 75 1e-12 UniRef50_Q6XPZ7 Cluster: Short-chain dehydrogenase/reductase; n=... 74 1e-12 UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella ve... 74 1e-12 UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR... 74 2e-12 UniRef50_Q28GY1 Cluster: Novel protein containing short chain de... 73 2e-12 UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR... 73 2e-12 UniRef50_Q6UWP2 Cluster: Dehydrogenase/reductase SDR family memb... 73 2e-12 UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacte... 73 3e-12 UniRef50_P19871 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=... 73 3e-12 UniRef50_Q7M9W0 Cluster: 3-OXOACYL-REDUCTASE; n=24; Epsilonprote... 72 5e-12 UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR... 72 5e-12 UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 72 5e-12 UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=... 72 7e-12 UniRef50_UPI00015B572E Cluster: PREDICTED: similar to putative a... 71 9e-12 UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR... 71 9e-12 UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogena... 71 9e-12 UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR... 71 9e-12 UniRef50_Q89M15 Cluster: Dehydrogenase; n=3; Proteobacteria|Rep:... 71 1e-11 UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 71 1e-11 UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR... 71 1e-11 UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019;... 71 1e-11 UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain dehydrogena... 71 2e-11 UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2; Actinom... 71 2e-11 UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductas... 71 2e-11 UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain dehydrogena... 70 2e-11 UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 70 3e-11 UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: O... 70 3e-11 UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1; Psychro... 70 3e-11 UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4; Legion... 70 3e-11 UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8;... 70 3e-11 UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain dehydrogena... 69 4e-11 UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 69 4e-11 UniRef50_Q3VZL7 Cluster: Short-chain dehydrogenase/reductase SDR... 69 4e-11 UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325;... 69 4e-11 UniRef50_A0X2J5 Cluster: Short-chain dehydrogenase/reductase SDR... 69 5e-11 UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular ... 69 7e-11 UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 69 7e-11 UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4; Brucel... 68 9e-11 UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 68 9e-11 UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 68 9e-11 UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular o... 67 2e-10 UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep... 67 2e-10 UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR... 67 2e-10 UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR... 67 2e-10 UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR... 67 2e-10 UniRef50_A6EZZ8 Cluster: Short chain dehydrogenase; n=1; Marinob... 67 2e-10 UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3; Bacill... 67 2e-10 UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR... 67 2e-10 UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR... 67 2e-10 UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20; ... 66 3e-10 UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 66 3e-10 UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n... 66 3e-10 UniRef50_Q7SI45 Cluster: Putative uncharacterized protein NCU006... 66 3e-10 UniRef50_P19992 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh... 66 3e-10 UniRef50_Q8CNF1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 66 3e-10 UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SD... 66 3e-10 UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 66 3e-10 UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5; Proteob... 66 3e-10 UniRef50_A4XF64 Cluster: Short-chain dehydrogenase/reductase SDR... 66 3e-10 UniRef50_Q9I7R3 Cluster: CG18814-PA; n=3; Sophophora|Rep: CG1881... 66 3e-10 UniRef50_Q54D03 Cluster: Putative uncharacterized protein; n=1; ... 66 3e-10 UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain dehydrogena... 66 5e-10 UniRef50_Q7W386 Cluster: Short chain dehydrogenase; n=111; cellu... 66 5e-10 UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR... 66 5e-10 UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR... 66 5e-10 UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1... 66 5e-10 UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain dehydrogena... 66 5e-10 UniRef50_Q71R50 Cluster: Dehydrogenase/reductase SDR family memb... 66 5e-10 UniRef50_UPI0000DB6B86 Cluster: PREDICTED: similar to CG9360-PA;... 65 6e-10 UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR... 65 6e-10 UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR... 65 6e-10 UniRef50_A1ULZ8 Cluster: Short-chain dehydrogenase/reductase SDR... 65 6e-10 UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR... 65 6e-10 UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR... 65 6e-10 UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid deh... 65 6e-10 UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase b... 65 6e-10 UniRef50_UPI00015B4F48 Cluster: PREDICTED: similar to ENSANGP000... 65 8e-10 UniRef50_Q89KQ8 Cluster: Blr4846 protein; n=2; Proteobacteria|Re... 65 8e-10 UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 65 8e-10 UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Sho... 65 8e-10 UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-car... 65 8e-10 UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR... 65 8e-10 UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR... 65 8e-10 UniRef50_A3XPR1 Cluster: Cyclohexanol dehydrogenase; n=1; Leeuwe... 65 8e-10 UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 65 8e-10 UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR... 64 1e-09 UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR... 64 1e-09 UniRef50_UPI0000518CA5 Cluster: PREDICTED: similar to antdh CG13... 64 1e-09 UniRef50_Q5LMX2 Cluster: 20-beta-hydroxysteroid dehydrogenase, p... 64 1e-09 UniRef50_Q0S5L2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 64 1e-09 UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogena... 64 1e-09 UniRef50_A6EGH2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 64 1e-09 UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 64 1e-09 UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillu... 64 1e-09 UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR... 64 1e-09 UniRef50_Q2UEK6 Cluster: Dehydrogenases with different specifici... 64 1e-09 UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase, puta... 64 1e-09 UniRef50_Q9C826 Cluster: Xanthoxin dehydrogenase; n=41; Magnolio... 64 1e-09 UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 64 2e-09 UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyc... 64 2e-09 UniRef50_Q7VXT8 Cluster: Probable short-chain dehydrogenase; n=3... 64 2e-09 UniRef50_Q2W431 Cluster: Dehydrogenase with different specificit... 64 2e-09 UniRef50_Q13H99 Cluster: Putative short-chain dehydrogenase/redu... 64 2e-09 UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 64 2e-09 UniRef50_A6W2S3 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09 UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bac... 64 2e-09 UniRef50_A3IK59 Cluster: Oxidoreductase, short chain dehydrogena... 64 2e-09 UniRef50_Q965D6 Cluster: 3-oxoacyl-acyl-carrier protein reductas... 64 2e-09 UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59; cell... 64 2e-09 UniRef50_UPI00015B452D Cluster: PREDICTED: similar to ENSANGP000... 63 2e-09 UniRef50_Q62E12 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 63 2e-09 UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR... 63 2e-09 UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR... 63 2e-09 UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x;... 63 2e-09 UniRef50_P50197 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio... 63 2e-09 UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 63 2e-09 UniRef50_Q9NAR7 Cluster: Alcohol dehydrogenase; n=23; Schizophor... 63 2e-09 UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 63 3e-09 UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Li... 63 3e-09 UniRef50_Q88SD1 Cluster: Short-chain dehydrogenase/oxidoreductas... 63 3e-09 UniRef50_Q81WX9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 63 3e-09 UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR... 63 3e-09 UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14;... 63 3e-09 UniRef50_P40747 Cluster: Uncharacterized oxidoreductase yuxG; n=... 63 3e-09 UniRef50_A7IMM1 Cluster: Short-chain dehydrogenase/reductase SDR... 62 4e-09 UniRef50_A2ULL1 Cluster: Short-chain dehydrogenase/reductase SDR... 62 4e-09 UniRef50_A0TVU3 Cluster: Short-chain dehydrogenase/reductase SDR... 62 4e-09 UniRef50_Q22CU9 Cluster: Oxidoreductase, short chain dehydrogena... 62 4e-09 UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627;... 62 4e-09 UniRef50_Q39TI0 Cluster: Short-chain dehydrogenase/reductase SDR... 62 6e-09 UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR... 62 6e-09 UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=... 62 6e-09 UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte... 62 6e-09 UniRef50_Q9SBM0 Cluster: Wts2L; n=3; core eudicotyledons|Rep: Wt... 62 6e-09 UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 62 8e-09 UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii K... 62 8e-09 UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxid... 62 8e-09 UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR... 62 8e-09 UniRef50_Q0FWE6 Cluster: Putative oxidoreductase; n=1; Roseovari... 62 8e-09 UniRef50_A7A2R8 Cluster: Putative uncharacterized protein; n=1; ... 62 8e-09 UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like ... 62 8e-09 UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR... 62 8e-09 UniRef50_A0KYX3 Cluster: Short-chain dehydrogenase/reductase SDR... 62 8e-09 UniRef50_Q9LW35 Cluster: Alcohol dehydrogenase-like protein; n=6... 62 8e-09 UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methano... 62 8e-09 UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 62 8e-09 UniRef50_Q89UC3 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 61 1e-08 UniRef50_Q3EU48 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 61 1e-08 UniRef50_Q12G63 Cluster: Short-chain dehydrogenase/reductase SDR... 61 1e-08 UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR... 61 1e-08 UniRef50_Q6NNV7 Cluster: RH03309p; n=4; melanogaster subgroup|Re... 61 1e-08 UniRef50_Q6IDG8 Cluster: RH36352p; n=2; Drosophila melanogaster|... 61 1e-08 UniRef50_A7EQI6 Cluster: Putative uncharacterized protein; n=1; ... 61 1e-08 UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium jap... 61 1e-08 UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reducta... 61 1e-08 UniRef50_Q1V2H3 Cluster: Short chain dehydrogenase; n=2; Candida... 61 1e-08 UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR... 61 1e-08 UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase prec... 61 1e-08 UniRef50_Q0S7P7 Cluster: Short chain dehydrogenase; n=7; Bacteri... 61 1e-08 UniRef50_A0JVX6 Cluster: Short-chain dehydrogenase/reductase SDR... 61 1e-08 UniRef50_A6XGT9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 61 1e-08 UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular organisms... 61 1e-08 UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34; Proteo... 61 1e-08 UniRef50_A7MR86 Cluster: Putative uncharacterized protein; n=1; ... 60 2e-08 UniRef50_A6VSM3 Cluster: Short-chain dehydrogenase/reductase SDR... 60 2e-08 UniRef50_A1UAJ6 Cluster: Acetoin reductases; n=18; Bacteria|Rep:... 60 2e-08 UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR... 60 2e-08 UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellula... 60 2e-08 UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR... 60 2e-08 UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3; Clo... 60 2e-08 UniRef50_UPI00015B5DCD Cluster: PREDICTED: similar to oxidoreduc... 60 2e-08 UniRef50_UPI00004996DD Cluster: 3-oxoacyl-(acyl-carrier protein)... 60 2e-08 UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chai... 60 2e-08 UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2; Bacteri... 60 2e-08 UniRef50_Q65F37 Cluster: Putative uncharacterized protein; n=1; ... 60 2e-08 UniRef50_Q5NM60 Cluster: Short-chain alcohol dehydrogenase; n=14... 60 2e-08 UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 60 2e-08 UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR... 60 2e-08 UniRef50_O32291 Cluster: YxnA protein; n=4; Bacteria|Rep: YxnA p... 60 2e-08 UniRef50_Q15Q07 Cluster: Short-chain dehydrogenase/reductase SDR... 60 2e-08 UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR... 60 2e-08 UniRef50_A0M3M9 Cluster: Short-chain dehydrogenase/reductase fam... 60 2e-08 UniRef50_Q5TWK5 Cluster: ENSANGP00000025423; n=1; Anopheles gamb... 60 2e-08 UniRef50_P52037 Cluster: Uncharacterized oxidoreductase ygfF; n=... 60 2e-08 UniRef50_P00334 Cluster: Alcohol dehydrogenase; n=485; Drosophil... 60 2e-08 UniRef50_Q9S3U5 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 60 3e-08 UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase... 60 3e-08 UniRef50_Q029B5 Cluster: Short-chain dehydrogenase/reductase SDR... 60 3e-08 UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR... 60 3e-08 UniRef50_O33454 Cluster: P-cumic alcohol dehydrogenase; n=3; Pro... 60 3e-08 UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR... 60 3e-08 UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 60 3e-08 UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1; ... 60 3e-08 UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR... 60 3e-08 UniRef50_A1SG64 Cluster: Short-chain dehydrogenase/reductase SDR... 60 3e-08 UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protei... 60 3e-08 UniRef50_A1FW82 Cluster: Short-chain dehydrogenase/reductase SDR... 60 3e-08 UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR... 60 3e-08 UniRef50_Q4WR19 Cluster: Short chain dehydrogenase, putative; n=... 60 3e-08 UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 60 3e-08 UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 60 3e-08 UniRef50_Q988B7 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 59 4e-08 UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specifici... 59 4e-08 UniRef50_Q8EDE2 Cluster: Oxidoreductase, short chain dehydrogena... 59 4e-08 UniRef50_Q1NK00 Cluster: Short-chain dehydrogenase/reductase SDR... 59 4e-08 UniRef50_Q0RTV0 Cluster: Short-chain dehydrogenase, SDR family; ... 59 4e-08 UniRef50_Q0B254 Cluster: Short-chain dehydrogenase/reductase SDR... 59 4e-08 UniRef50_A6VY27 Cluster: Short-chain dehydrogenase/reductase SDR... 59 4e-08 UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain dehydrogena... 59 4e-08 UniRef50_A0PSE4 Cluster: Short-chain type dehydrogenase; n=12; C... 59 4e-08 UniRef50_Q7Q3Q2 Cluster: ENSANGP00000007118; n=1; Anopheles gamb... 59 4e-08 UniRef50_Q0UTY3 Cluster: Putative uncharacterized protein; n=1; ... 59 4e-08 UniRef50_Q0UAH4 Cluster: Putative uncharacterized protein; n=1; ... 59 4e-08 UniRef50_Q5UYC2 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 59 4e-08 UniRef50_O29061 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 59 4e-08 UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2; Corynebac... 59 5e-08 UniRef50_Q54472 Cluster: Oxido-reductase; n=3; Bacteria|Rep: Oxi... 59 5e-08 UniRef50_A6LUV1 Cluster: Short-chain dehydrogenase/reductase SDR... 59 5e-08 UniRef50_A3IBN0 Cluster: Predicted short chain dehydrogenase; n=... 59 5e-08 UniRef50_A2U5Y6 Cluster: Short-chain dehydrogenase/reductase SDR... 59 5e-08 UniRef50_A0Z215 Cluster: Short chain dehydrogenase; n=2; Gammapr... 59 5e-08 UniRef50_Q9LW34 Cluster: Alcohol dehydrogenase-like protein; n=6... 59 5e-08 UniRef50_UPI0000E498BD Cluster: PREDICTED: similar to Carbonyl r... 58 7e-08 UniRef50_Q392K1 Cluster: Short-chain dehydrogenase/reductase SDR... 58 7e-08 UniRef50_Q24QX0 Cluster: Putative uncharacterized protein; n=1; ... 58 7e-08 UniRef50_Q11ZZ1 Cluster: Short-chain dehydrogenase/reductase SDR... 58 7e-08 UniRef50_A4B8L3 Cluster: Short chain dehydrogenase; n=1; Alterom... 58 7e-08 UniRef50_A3Q491 Cluster: Short-chain dehydrogenase/reductase SDR... 58 7e-08 UniRef50_A1K1F1 Cluster: Short-chain dehydrogenase family protei... 58 7e-08 UniRef50_A0Z7K1 Cluster: Short-chain dehydrogenase/reductase SDR... 58 7e-08 UniRef50_A0G4K1 Cluster: Short-chain dehydrogenase/reductase SDR... 58 7e-08 UniRef50_Q0DM18 Cluster: Os03g0833100 protein; n=5; Oryza sativa... 58 7e-08 UniRef50_P54398 Cluster: Fat body protein 2; n=6; Schizophora|Re... 58 7e-08 UniRef50_Q59787 Cluster: Sorbitol dehydrogenase; n=60; Bacteria|... 58 7e-08 UniRef50_UPI00015B5CBB Cluster: PREDICTED: similar to ENSANGP000... 58 9e-08 UniRef50_UPI0000E46681 Cluster: PREDICTED: similar to carbonyl r... 58 9e-08 UniRef50_Q8F3S6 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 58 9e-08 UniRef50_Q7W4M0 Cluster: Putative oxidoreductase; n=2; Bordetell... 58 9e-08 UniRef50_Q8GR61 Cluster: Xylitol dehydrogenase; n=2; Gluconobact... 58 9e-08 UniRef50_Q52JK0 Cluster: PhaB; n=16; Bacteria|Rep: PhaB - Bacill... 58 9e-08 UniRef50_Q03X86 Cluster: Putative uncharacterized protein; n=1; ... 58 9e-08 UniRef50_A4XEV6 Cluster: Short-chain dehydrogenase/reductase SDR... 58 9e-08 UniRef50_A0HI81 Cluster: Short-chain dehydrogenase/reductase SDR... 58 9e-08 UniRef50_Q94G10 Cluster: CTA; n=3; Cucumis sativus|Rep: CTA - Cu... 58 9e-08 UniRef50_A2YPN0 Cluster: Putative uncharacterized protein; n=3; ... 58 9e-08 UniRef50_Q2UV13 Cluster: Reductases with broad range of substrat... 58 9e-08 UniRef50_Q4J9S4 Cluster: Glucose 1-dehydrogenase; n=6; Thermopro... 58 9e-08 UniRef50_A0RX79 Cluster: Short-chain alcohol dehydrogenase; n=1;... 58 9e-08 UniRef50_Q8UHH7 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 58 1e-07 UniRef50_Q829D6 Cluster: Putative dehydrogenase; n=2; Streptomyc... 58 1e-07 UniRef50_Q65SP1 Cluster: FabG protein; n=10; Bacteria|Rep: FabG ... 58 1e-07 UniRef50_Q65QK8 Cluster: FabG protein; n=1; Mannheimia succinici... 58 1e-07 UniRef50_Q2S7V4 Cluster: Short-chain alcohol dehydrogenase-like ... 58 1e-07 UniRef50_Q93QG5 Cluster: Cyclohexanol dehydrogenase; n=4; Bacter... 58 1e-07 UniRef50_Q2CEF3 Cluster: Dehydrogenase; n=1; Oceanicola granulos... 58 1e-07 UniRef50_Q1AYL3 Cluster: Short-chain dehydrogenase/reductase SDR... 58 1e-07 UniRef50_Q0RYG0 Cluster: (+)-trans-carveol dehydrogenase; n=3; A... 58 1e-07 UniRef50_Q0I8V1 Cluster: Glucose 1-dehydrogenase; n=5; Bacteria|... 58 1e-07 UniRef50_A7IJ54 Cluster: Short-chain dehydrogenase/reductase SDR... 58 1e-07 UniRef50_A7HWE4 Cluster: Short-chain dehydrogenase/reductase SDR... 58 1e-07 UniRef50_A7AZH2 Cluster: Putative uncharacterized protein; n=1; ... 58 1e-07 UniRef50_A3W7Y7 Cluster: Putative uncharacterized protein; n=3; ... 58 1e-07 UniRef50_A3JFT9 Cluster: Short chain dehydrogenase; n=1; Marinob... 58 1e-07 UniRef50_A1ZL47 Cluster: Oxidoreductase, short chain dehydrogena... 58 1e-07 UniRef50_A0R6X9 Cluster: Cyclopentanol dehydrogenase; n=2; Bacte... 58 1e-07 UniRef50_A0QIV9 Cluster: Short chain dehydrogenase; n=5; root|Re... 58 1e-07 UniRef50_Q9M1K9 Cluster: Alcohol dehydrogenase; n=6; core eudico... 58 1e-07 UniRef50_A7S4C5 Cluster: Predicted protein; n=1; Nematostella ve... 58 1e-07 UniRef50_A0DCG9 Cluster: Chromosome undetermined scaffold_45, wh... 58 1e-07 UniRef50_Q92EK7 Cluster: Uncharacterized oxidoreductase Lin0452;... 58 1e-07 UniRef50_UPI00015B4F47 Cluster: PREDICTED: similar to short-chai... 57 2e-07 UniRef50_UPI0000E4A41A Cluster: PREDICTED: similar to Retinol de... 57 2e-07 UniRef50_UPI000023EE28 Cluster: hypothetical protein FG08816.1; ... 57 2e-07 UniRef50_Q890G1 Cluster: Short-chain dehydrogenase/oxidoreductas... 57 2e-07 UniRef50_Q6MR20 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 57 2e-07 UniRef50_Q48I17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 57 2e-07 UniRef50_Q39N51 Cluster: Short-chain dehydrogenase/reductase SDR... 57 2e-07 UniRef50_Q1YZB6 Cluster: Short chain dehydrogenase; n=6; Gammapr... 57 2e-07 UniRef50_Q1AZ56 Cluster: Short-chain dehydrogenase/reductase SDR... 57 2e-07 UniRef50_Q13HC1 Cluster: Putative short-chain dehydrogenase/redu... 57 2e-07 UniRef50_Q11E37 Cluster: Short-chain dehydrogenase/reductase SDR... 57 2e-07 UniRef50_Q0HV76 Cluster: Short-chain dehydrogenase/reductase SDR... 57 2e-07 UniRef50_A6BFV0 Cluster: Putative uncharacterized protein; n=1; ... 57 2e-07 UniRef50_A4M6M0 Cluster: Short-chain dehydrogenase/reductase SDR... 57 2e-07 UniRef50_A4AAT7 Cluster: Short-chain dehydrogenase/reductase SDR... 57 2e-07 UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 57 2e-07 UniRef50_Q5IWZ4 Cluster: Plastid 3-oxoacyl-[acyl-carrier protein... 57 2e-07 UniRef50_Q22RI1 Cluster: Oxidoreductase, short chain dehydrogena... 57 2e-07 UniRef50_Q17G49 Cluster: Oxidoreductase; n=2; Culicidae|Rep: Oxi... 57 2e-07 UniRef50_Q6BR06 Cluster: Similar to CA3771|CaSOU1 Candida albica... 57 2e-07 UniRef50_Q2UB74 Cluster: Predicted protein; n=1; Aspergillus ory... 57 2e-07 UniRef50_Q2GUJ6 Cluster: Putative uncharacterized protein; n=2; ... 57 2e-07 UniRef50_A0RXB6 Cluster: Short-chain alcohol dehydrogenase; n=2;... 57 2e-07 UniRef50_Q9BPX1 Cluster: Dehydrogenase/reductase SDR family memb... 57 2e-07 UniRef50_UPI0000E465C5 Cluster: PREDICTED: similar to MGC80593 p... 57 2e-07 UniRef50_UPI000023CB88 Cluster: hypothetical protein FG04599.1; ... 57 2e-07 UniRef50_Q9L2C9 Cluster: Putative dehydrogenase; n=2; Streptomyc... 57 2e-07 UniRef50_Q88T73 Cluster: Short-chain dehydrogenase/oxidoreductas... 57 2e-07 UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogena... 57 2e-07 UniRef50_Q0SC53 Cluster: Dehydrogenase; n=3; Corynebacterineae|R... 57 2e-07 UniRef50_Q8GFA6 Cluster: Orf29; n=6; Gammaproteobacteria|Rep: Or... 57 2e-07 UniRef50_Q11BT3 Cluster: Short-chain dehydrogenase/reductase SDR... 57 2e-07 UniRef50_A5GRS5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 57 2e-07 UniRef50_A3TVX6 Cluster: Probable dehydrogenase; n=1; Oceanicola... 57 2e-07 UniRef50_A3JX84 Cluster: Short chain dehydrogenase; n=5; Alphapr... 57 2e-07 UniRef50_A1ZM53 Cluster: Short chain dehydrogenase; n=1; Microsc... 57 2e-07 UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR... 57 2e-07 UniRef50_Q9N5G3 Cluster: Dehydrogenases, short chain protein 14;... 57 2e-07 UniRef50_A4QV37 Cluster: Putative uncharacterized protein; n=1; ... 57 2e-07 UniRef50_Q97SL2 Cluster: Oxidoreductase, short chain dehydrogena... 56 3e-07 UniRef50_Q8EMX3 Cluster: Hypothetical conserved protein; n=1; Oc... 56 3e-07 UniRef50_Q7UMF1 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 56 3e-07 UniRef50_Q55922 Cluster: Slr0315 protein; n=2; Bacteria|Rep: Slr... 56 3e-07 UniRef50_Q39TR6 Cluster: Short-chain dehydrogenase/reductase SDR... 56 3e-07 UniRef50_Q2G823 Cluster: Short-chain dehydrogenase/reductase SDR... 56 3e-07 UniRef50_Q8KY44 Cluster: RubJ; n=3; Streptomyces|Rep: RubJ - Str... 56 3e-07 UniRef50_Q3WA78 Cluster: Short-chain dehydrogenase/reductase SDR... 56 3e-07 UniRef50_Q192C0 Cluster: Short-chain dehydrogenase/reductase SDR... 56 3e-07 UniRef50_Q12HD3 Cluster: Short-chain dehydrogenase/reductase SDR... 56 3e-07 UniRef50_Q11G59 Cluster: Short-chain dehydrogenase/reductase SDR... 56 3e-07 UniRef50_A6X7S0 Cluster: Short-chain dehydrogenase/reductase SDR... 56 3e-07 UniRef50_A6W9N2 Cluster: Short-chain dehydrogenase/reductase SDR... 56 3e-07 UniRef50_A4ALI9 Cluster: Putative short chain dehydrogenase; n=2... 56 3e-07 UniRef50_A3WIC9 Cluster: Oxidoreductase, short chain dehydrogena... 56 3e-07 UniRef50_A1WSD4 Cluster: Short-chain dehydrogenase/reductase SDR... 56 3e-07 UniRef50_A1U9L1 Cluster: Short-chain dehydrogenase/reductase SDR... 56 3e-07 UniRef50_A0YD08 Cluster: Short chain dehydrogenase; n=2; Gammapr... 56 3e-07 UniRef50_A0QGC5 Cluster: Sorbitol utilization protein SOU1; n=3;... 56 3e-07 UniRef50_A0JVB1 Cluster: Short-chain dehydrogenase/reductase SDR... 56 3e-07 UniRef50_A3BN50 Cluster: Putative uncharacterized protein; n=2; ... 56 3e-07 UniRef50_Q4P1S7 Cluster: Putative uncharacterized protein; n=1; ... 56 3e-07 UniRef50_Q4RS15 Cluster: Chromosome 7 SCAF15001, whole genome sh... 50 4e-07 UniRef50_Q8KKW9 Cluster: Putative oxidoreductase protein; n=1; R... 56 4e-07 UniRef50_Q62CL0 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 56 4e-07 UniRef50_Q2G758 Cluster: Short-chain dehydrogenase/reductase SDR... 56 4e-07 UniRef50_Q1YS63 Cluster: Putative dehydrogenase; n=1; gamma prot... 56 4e-07 UniRef50_Q1IU02 Cluster: Short-chain dehydrogenase/reductase SDR... 56 4e-07 UniRef50_Q140J4 Cluster: Putative 3-oxoacyl-(Acyl-carrier protei... 56 4e-07 UniRef50_Q0TM71 Cluster: Oxidoreductase, short chain dehydrogena... 56 4e-07 UniRef50_A6GRZ3 Cluster: Short chain dehydrogenase; n=1; Limnoba... 56 4e-07 UniRef50_A3I6G4 Cluster: Putative 7-alpha-hydroxysteroid dehydro... 56 4e-07 UniRef50_A1ZK52 Cluster: Dehydrogenase/reductase SDR family memb... 56 4e-07 UniRef50_A0JSI8 Cluster: Short-chain dehydrogenase/reductase SDR... 56 4e-07 UniRef50_Q5CAF5 Cluster: Neomenthol dehydrogenase; n=5; core eud... 56 4e-07 UniRef50_Q0U1A7 Cluster: Putative uncharacterized protein; n=1; ... 56 4e-07 UniRef50_P46331 Cluster: Uncharacterized oxidoreductase yxbG; n=... 56 4e-07 UniRef50_P12310 Cluster: Glucose 1-dehydrogenase; n=13; cellular... 56 4e-07 UniRef50_Q8FA17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 56 5e-07 UniRef50_Q8EPA2 Cluster: Hypothetical conserved protein; n=1; Oc... 56 5e-07 UniRef50_Q390G9 Cluster: Short-chain dehydrogenase/reductase SDR... 56 5e-07 UniRef50_Q5KRC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 56 5e-07 UniRef50_Q3WJ90 Cluster: Short-chain dehydrogenase/reductase SDR... 56 5e-07 UniRef50_Q2AGJ3 Cluster: NAD-dependent epimerase/dehydratase:Sho... 56 5e-07 UniRef50_Q0M0K7 Cluster: Short-chain dehydrogenase/reductase SDR... 56 5e-07 UniRef50_A6ELE5 Cluster: Short-chain dehydrogenase/reductase SDR... 56 5e-07 UniRef50_A5ZP03 Cluster: Putative uncharacterized protein; n=1; ... 56 5e-07 UniRef50_A4CNY9 Cluster: Oxidoreductase, short chain dehydrogena... 56 5e-07 UniRef50_A3TS19 Cluster: Short-chain dehydrogenase; n=1; Janibac... 56 5e-07 UniRef50_A1IFS9 Cluster: Short chain dehydrogenase family protei... 56 5e-07 UniRef50_Q9XYN2 Cluster: Antennal-specific short-chain dehydroge... 56 5e-07 UniRef50_Q5BII6 Cluster: RH05486p; n=4; Sophophora|Rep: RH05486p... 56 5e-07 UniRef50_A0D0S7 Cluster: Chromosome undetermined scaffold_33, wh... 56 5e-07 UniRef50_Q8TMH3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 56 5e-07 UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR... 56 5e-07 UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;... 56 5e-07 UniRef50_Q9K636 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct... 55 7e-07 UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -... 55 7e-07 UniRef50_Q8YVT0 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 55 7e-07 UniRef50_Q8YIP9 Cluster: 2-DEOXY-D-GLUCONATE 3-DEHYDROGENASE; n=... 55 7e-07 UniRef50_Q897E2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 55 7e-07 UniRef50_Q82FK0 Cluster: Putative dehydrogenase; n=2; Streptomyc... 55 7e-07 UniRef50_Q7MAW1 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 55 7e-07 UniRef50_Q46UI8 Cluster: Short-chain dehydrogenase/reductase SDR... 55 7e-07 UniRef50_Q1N373 Cluster: Putative fatty acyl chain reductase; n=... 55 7e-07 UniRef50_Q18SE9 Cluster: Short-chain dehydrogenase/reductase SDR... 55 7e-07 UniRef50_Q11BT8 Cluster: Short-chain dehydrogenase/reductase SDR... 55 7e-07 UniRef50_A1TC76 Cluster: Short-chain dehydrogenase/reductase SDR... 55 7e-07 UniRef50_A0Z4N7 Cluster: Short chain dehydrogenase; n=2; Bacteri... 55 7e-07 UniRef50_A0Z2D1 Cluster: Short-chain dehydrogenase/reductase (SD... 55 7e-07 UniRef50_A0XX22 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 55 7e-07 UniRef50_A0UJ74 Cluster: Beta-ketoacyl synthase; n=2; Bacteria|R... 55 7e-07 UniRef50_A0TW00 Cluster: Short-chain dehydrogenase/reductase SDR... 55 7e-07 UniRef50_A0PSR4 Cluster: Short-chain dehydrogenase; n=1; Mycobac... 55 7e-07 UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR... 55 7e-07 UniRef50_A0LJK6 Cluster: Short-chain dehydrogenase/reductase SDR... 55 7e-07 UniRef50_Q0D3U7 Cluster: Os07g0665000 protein; n=18; Poales|Rep:... 55 7e-07 UniRef50_A5BP77 Cluster: Putative uncharacterized protein; n=1; ... 55 7e-07 UniRef50_Q75DB1 Cluster: ABR248Wp; n=4; Eremothecium gossypii|Re... 55 7e-07 UniRef50_A2QS57 Cluster: Contig An08c0220, complete genome; n=2;... 55 7e-07 UniRef50_Q5V623 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 55 7e-07 UniRef50_P50160 Cluster: Sex determination protein tasselseed-2;... 55 7e-07 UniRef50_Q04520 Cluster: Acetoin(diacetyl) reductase; n=1; Raoul... 55 7e-07 UniRef50_UPI0000DAE1BB Cluster: oxidoreductase, short chain dehy... 55 9e-07 UniRef50_UPI000045C1E7 Cluster: COG1028: Dehydrogenases with dif... 55 9e-07 UniRef50_Q87GW0 Cluster: Acetoacetyl-CoA reductase; n=7; Vibrio|... 55 9e-07 UniRef50_Q73Q46 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 55 9e-07 UniRef50_Q2IEG2 Cluster: Short-chain dehydrogenase/reductase SDR... 55 9e-07 UniRef50_O86553 Cluster: Putative dehydrogenase; n=1; Streptomyc... 55 9e-07 UniRef50_Q1YPA9 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 55 9e-07 UniRef50_Q1GUT4 Cluster: Short-chain dehydrogenase/reductase SDR... 55 9e-07 UniRef50_Q1AYC7 Cluster: Short-chain dehydrogenase/reductase SDR... 55 9e-07 UniRef50_Q13I70 Cluster: Putative short-chain dehydrogenase/redu... 55 9e-07 UniRef50_Q0S4U3 Cluster: Dehydrogenase; n=2; Actinomycetales|Rep... 55 9e-07 UniRef50_Q0RIJ2 Cluster: Putative short chain dehydrogenase/redu... 55 9e-07 UniRef50_Q0LC46 Cluster: Short-chain dehydrogenase/reductase SDR... 55 9e-07 UniRef50_A5TX02 Cluster: Short-chain alcohol dehydrogenase; n=3;... 55 9e-07 UniRef50_A3UA16 Cluster: Acetoin(Diacetyl)reductase; n=6; Bacter... 55 9e-07 UniRef50_A1UMZ0 Cluster: Short-chain dehydrogenase/reductase SDR... 55 9e-07 UniRef50_A1K6U9 Cluster: Short-chain dehydrogenase family protei... 55 9e-07 UniRef50_Q17D91 Cluster: Short-chain dehydrogenase; n=2; Aedes a... 55 9e-07 UniRef50_Q4PIF5 Cluster: Putative uncharacterized protein; n=1; ... 55 9e-07 UniRef50_Q2FSZ0 Cluster: Short-chain dehydrogenase/reductase SDR... 55 9e-07 UniRef50_A3CU09 Cluster: Short-chain dehydrogenase/reductase SDR... 55 9e-07 UniRef50_P39071 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate dehyd... 55 9e-07 UniRef50_A5CFS4 Cluster: Short-chain dehydrogenase/reductase SDR... 54 1e-06 UniRef50_Q8EY23 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 54 1e-06 UniRef50_Q8EQ60 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 54 1e-06 UniRef50_Q88LH9 Cluster: Oxidoreductase, short chain dehydrogena... 54 1e-06 UniRef50_Q74FZ1 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 54 1e-06 UniRef50_Q737G7 Cluster: Short chain dehydrogenase family protei... 54 1e-06 UniRef50_Q5WBV7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 54 1e-06 UniRef50_Q3WFP9 Cluster: Short-chain dehydrogenase/reductase SDR... 54 1e-06 UniRef50_Q26DV9 Cluster: Short-chain dehydrogenases/reductases f... 54 1e-06 UniRef50_Q1ZSP4 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n... 54 1e-06 UniRef50_Q1NAB3 Cluster: Short-chain dehydrogenase/reductase SDR... 54 1e-06 UniRef50_Q1LBV3 Cluster: Short-chain dehydrogenase/reductase SDR... 54 1e-06 UniRef50_Q18QN3 Cluster: Short-chain dehydrogenase/reductase SDR... 54 1e-06 UniRef50_A7IEE4 Cluster: Short-chain dehydrogenase/reductase SDR... 54 1e-06 UniRef50_A7HL35 Cluster: Short-chain dehydrogenase/reductase SDR... 54 1e-06 UniRef50_A6GFU2 Cluster: Short chain dehydrogenase; n=1; Plesioc... 54 1e-06 UniRef50_A6DG05 Cluster: Short chain dehydrogenase; n=1; Lentisp... 54 1e-06 UniRef50_A6CM25 Cluster: Oxidoreductase, short chain dehydrogena... 54 1e-06 UniRef50_A3IAI0 Cluster: Short-chain dehydrogenase/reductase SDR... 54 1e-06 UniRef50_A0QN49 Cluster: NAD dependent epimerase/dehydratase fam... 54 1e-06 UniRef50_A0LZZ5 Cluster: Short-chain dehydrogenase/reductase fam... 54 1e-06 UniRef50_Q9FX95 Cluster: ARP protein; n=8; Magnoliophyta|Rep: AR... 54 1e-06 UniRef50_Q9VU92 Cluster: CG8757-PA; n=3; Drosophila melanogaster... 54 1e-06 UniRef50_A7RYH1 Cluster: Predicted protein; n=7; Eumetazoa|Rep: ... 54 1e-06 UniRef50_Q14RS1 Cluster: ABA4 protein; n=4; Pezizomycotina|Rep: ... 54 1e-06 UniRef50_A6RBN3 Cluster: Predicted protein; n=1; Ajellomyces cap... 54 1e-06 UniRef50_Q5V0V4 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 54 1e-06 UniRef50_A2BJK2 Cluster: Short chain dehydrogenase; n=1; Hyperth... 54 1e-06 UniRef50_Q9Y394 Cluster: Dehydrogenase/reductase SDR family memb... 54 1e-06 UniRef50_Q9AK65 Cluster: Putative glucose 1-dehydrogenase; n=2; ... 54 2e-06 UniRef50_Q89HU1 Cluster: Bll5898 protein; n=36; Proteobacteria|R... 54 2e-06 UniRef50_Q833Z8 Cluster: Short chain dehydrogenase; n=23; Bacill... 54 2e-06 UniRef50_Q62GZ1 Cluster: Oxidoreductase, short chain dehydrogena... 54 2e-06 UniRef50_Q57A51 Cluster: Oxidoreductase, short-chain dehydrogena... 54 2e-06 UniRef50_Q84EX5 Cluster: R-specific alcohol dehydrogenase; n=5; ... 54 2e-06 UniRef50_Q1DCG1 Cluster: Oxidoreductase, short-chain dehydrogena... 54 2e-06 UniRef50_Q1BF92 Cluster: Short-chain dehydrogenase/reductase SDR... 54 2e-06 UniRef50_Q0KJ73 Cluster: Putative ribitol degydrogenase; short-c... 54 2e-06 UniRef50_Q094I4 Cluster: NAD-dependent epimerase/dehydratase; n=... 54 2e-06 UniRef50_A5UT09 Cluster: Short-chain dehydrogenase/reductase SDR... 54 2e-06 UniRef50_A4QHZ4 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-06 UniRef50_A4CPX8 Cluster: Short chain dehydrogenase; n=2; Bacteri... 54 2e-06 UniRef50_A4A7M5 Cluster: Short chain dehydrogenase family protei... 54 2e-06 UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR... 54 2e-06 UniRef50_A3SDR3 Cluster: Putative 3-oxoacyl-acyl carrier protein... 54 2e-06 UniRef50_A1UA98 Cluster: Short-chain dehydrogenase/reductase SDR... 54 2e-06 UniRef50_A0QZR1 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=... 54 2e-06 UniRef50_A0KRX7 Cluster: Short-chain dehydrogenase/reductase SDR... 54 2e-06 UniRef50_Q5D0Q8 Cluster: Nonribosomal peptide synthetase 10; n=1... 54 2e-06 UniRef50_Q0UZK8 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-06 UniRef50_A4R3Y6 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-06 UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=... 54 2e-06 >UniRef50_Q6NYE8 Cluster: Zgc:56585 protein; n=5; Clupeocephala|Rep: Zgc:56585 protein - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 270 Score = 125 bits (302), Expect = 4e-28 Identities = 59/142 (41%), Positives = 95/142 (66%), Gaps = 1/142 (0%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 196 KDKV +TGAA G+G S V IL+ G K +A++D+ + G+ L+ LN +YG N+ +FY Sbjct: 4 KDKVAVVTGAAQGLGRSFVEILMKNGSK-VALIDVNKSLGEELKTNLNKEYGPNRAEFYT 62 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 376 +DV+ EE F G+L +V++ G ID++ NNA ++N+ ++K I +N+ ++ T A+E Sbjct: 63 ADVSSEEDFKGVLKKIVEQFGQIDIMCNNAGIINEK--HWEKTIAINLGGVVRGTYLALE 120 Query: 377 IMGKHSGGKGGTVINVSSVAAL 442 M K +GG GG ++NV+S+A L Sbjct: 121 YMKKENGGSGGVIVNVASMAGL 142 >UniRef50_Q1G151 Cluster: Putative alcohol dehydrogenase; n=1; Bombyx mori|Rep: Putative alcohol dehydrogenase - Bombyx mori (Silk moth) Length = 274 Score = 118 bits (284), Expect = 6e-26 Identities = 57/147 (38%), Positives = 90/147 (61%), Gaps = 2/147 (1%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKFYRS 199 DKV +TG A G+G +V+ LL E +H+A LD+A+ G +L+ +L K+G + KF + Sbjct: 14 DKVFLVTGGAAGVGAGLVKALLFENARHVAFLDVADREGAALEAQLIIKFGALRVKFIKC 73 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 379 DV DE V+ + +D VIN+AA+++ + + I++N T + STLKA++I Sbjct: 74 DVGDERQLASAYKQVLDKYKRLDGVINSAAVLSVDDNSFNRMIDINFTGTVNSTLKALDI 133 Query: 380 MGKHSGGKGGTVINVSSVAALT-QSHV 457 MG GG GG ++N+SS+ AL SH+ Sbjct: 134 MGADKGGSGGVIVNISSLLALNLTSHL 160 >UniRef50_UPI0000DB7440 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase; n=1; Apis mellifera|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase - Apis mellifera Length = 266 Score = 110 bits (265), Expect = 1e-23 Identities = 59/142 (41%), Positives = 91/142 (64%), Gaps = 1/142 (0%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 196 KDK V ITG A+G+G ++ R LL G IA++D AEE+GK LN ++G N+T FY Sbjct: 4 KDKRVIITGVASGLGLTISRELLRNGASIIAMID-AEESGKETVDILNKEFGRNRTIFYH 62 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 376 ++ + F V+ GG+++++NNA + N++ + K I+VNVT++I +TL I+ Sbjct: 63 CNIANNSEFDDTFKKAVKALGGLEILVNNADVTNET--DFMKTIDVNVTSVIRATLLGIQ 120 Query: 377 IMGKHSGGKGGTVINVSSVAAL 442 M K GGKGG ++N+SS+A L Sbjct: 121 QMQKDLGGKGGAIVNISSLAGL 142 >UniRef50_UPI00015B573D Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 279 Score = 108 bits (259), Expect = 7e-23 Identities = 56/148 (37%), Positives = 87/148 (58%), Gaps = 1/148 (0%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 196 KDKV+ +TG A GIG V L++G +++AILDI E +L ++G ++ Y Sbjct: 11 KDKVIIVTGGANGIGLECVLEFLEKGARYVAILDITPE--NFTADKLQEEFGTHRVDLYH 68 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 376 D+ +EE F V+++ +D++IN+A + N++ + ++VNV I L AIE Sbjct: 69 CDIANEEEFRSNFKKVIEKHNYVDILINDAGVANENDTA--RLLDVNVKGTILGNLMAIE 126 Query: 377 IMGKHSGGKGGTVINVSSVAALTQSHVM 460 MGKH GG+GG V+NV+SV L HV+ Sbjct: 127 HMGKHKGGRGGVVVNVASVIGLLNCHVL 154 >UniRef50_UPI00015B42E5 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=3; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 273 Score = 107 bits (256), Expect = 2e-22 Identities = 50/143 (34%), Positives = 90/143 (62%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 193 E KDKVV ITG +GIG S+ + +L G K++A+ ++ E + + EL+ +Y ++ FY Sbjct: 19 EVKDKVVVITGGTSGIGLSIAKHMLKNGAKYVALFELDHENSRIVFDELHKQYHDRIGFY 78 Query: 194 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 373 DVT + + V++ ID++INNA + +D+ + ++++N+ AL+ ++ K I Sbjct: 79 PCDVTKTDLIYNNFDKVMESHKTIDILINNAGIADDNKP--ELSVDINLKALVVASYKFI 136 Query: 374 EIMGKHSGGKGGTVINVSSVAAL 442 +GKH GGKGG ++N++S+A + Sbjct: 137 ARIGKHKGGKGGVIVNIASIAGI 159 >UniRef50_UPI00015B42DD Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 261 Score = 105 bits (252), Expect = 5e-22 Identities = 52/141 (36%), Positives = 88/141 (62%), Gaps = 1/141 (0%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 202 +KV ITG A GIG ++V+ LL+ G+K +A+ D+ K + ++L KYGN+ + Y D Sbjct: 5 NKVAIITGGAGGIGAAIVKRLLEHGIKLVALFDLDNSNTKKIFMDLQKKYGNRVELYPCD 64 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK-AIEVNVTALITSTLKAIEI 379 VT++ F + V++ ID+++NNA + +D I+ + I++N A++ +L IE Sbjct: 65 VTNKAQFEENFDKVLKTHKTIDILLNNAGIGSD---IHTELMIDLNYKAVVLGSLLFIER 121 Query: 380 MGKHSGGKGGTVINVSSVAAL 442 +GKH GGKGG ++N +S+ L Sbjct: 122 LGKHKGGKGGIIVNTASILGL 142 >UniRef50_Q6RUR3 Cluster: Putative alcohol dehydrogenase; n=2; Neoptera|Rep: Putative alcohol dehydrogenase - Gryllotalpa orientalis (Oriental mole cricket) Length = 266 Score = 104 bits (250), Expect = 8e-22 Identities = 53/142 (37%), Positives = 85/142 (59%), Gaps = 1/142 (0%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 196 K K +TG ATGIG + V+ LL GV+ +A+ D+ E G + +LN ++G K F + Sbjct: 4 KGKYALVTGGATGIGLAYVKELLRHGVQAVAVADLDERKGDNSVKQLNDEFGAGKAIFIK 63 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 376 DVT+++ G+D+VINNA +++DS ++ I +NVTA+ T A + Sbjct: 64 CDVTNKDDLEATFRKAAATFKGLDIVINNAGILDDSR--WETEIAINVTAVARGTWLAFD 121 Query: 377 IMGKHSGGKGGTVINVSSVAAL 442 +MGK+ GG+GG V+N++S+ L Sbjct: 122 LMGKNKGGRGGVVVNIASILGL 143 >UniRef50_UPI0000513348 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase; n=2; Apis mellifera|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase - Apis mellifera Length = 263 Score = 101 bits (243), Expect = 6e-21 Identities = 51/142 (35%), Positives = 82/142 (57%), Gaps = 1/142 (0%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKFYR 196 K+K ITG G+G + LL+ G K +A+LD++ G+ L ++G K FY Sbjct: 6 KNKTALITGGTVGLGLIYAKRLLENGAKCVALLDLSSSPGQQTVNNLEKEFGKGKAIFYA 65 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 376 DV++ F + VV + G+D+VINNA + ND +++ + +NV +I +L A + Sbjct: 66 CDVSNINEFEAVFKKVVNDLNGLDIVINNAGIYNDKK--WEQTMCINVGGVIQGSLLAFD 123 Query: 377 IMGKHSGGKGGTVINVSSVAAL 442 M K GGKGGT++N++S+ AL Sbjct: 124 HMSKLKGGKGGTIVNIASIVAL 145 >UniRef50_UPI0000E47587 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase (NAD+), partial; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase (NAD+), partial - Strongylocentrotus purpuratus Length = 298 Score = 100 bits (239), Expect = 2e-20 Identities = 51/139 (36%), Positives = 84/139 (60%), Gaps = 1/139 (0%) Frame = +2 Query: 29 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 205 V ITGAA G G++ LL V+ I I+D GK+ + ELN KYG +K +F++ DV Sbjct: 46 VALITGAAEGFGKAFTEELLKRSVRGIGIVDFNAAKGKATETELNKKYGEDKVRFFQCDV 105 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 385 + ++ + ++ GID+V NNA + D + ++K ++V++ A++ T A + M Sbjct: 106 SSKDQLEDAFSKTLEHYKGIDIVCNNAGI-GDELN-WEKTVDVDLVAVMRGTFLAKQYMD 163 Query: 386 KHSGGKGGTVINVSSVAAL 442 K+ GG+GG VIN++S+A L Sbjct: 164 KNKGGRGGIVINIASMAGL 182 >UniRef50_UPI00015B5316 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 329 Score = 99 bits (238), Expect = 2e-20 Identities = 49/142 (34%), Positives = 83/142 (58%), Gaps = 1/142 (0%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 196 KDK + GA G+G + + LL GV + ++D+ E G++ LN ++G N+ F + Sbjct: 71 KDKKAMVIGACDGLGMAFSKELLRNGVARVLMIDMNETLGRAQADRLNEEFGRNRATFTK 130 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 376 DVT F V G +D+++NNAA++ D + ++ I+ NVTA+ +++ ++ Sbjct: 131 CDVTKGSEFDACFKDAVNTLGALDIIVNNAAMI-DEVNFHR-TIDTNVTAVFRASMMGVQ 188 Query: 377 IMGKHSGGKGGTVINVSSVAAL 442 MGK +GGKGG ++NV+SV L Sbjct: 189 QMGKDTGGKGGVIVNVASVLGL 210 >UniRef50_UPI00015B4C63 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 271 Score = 98.3 bits (234), Expect = 7e-20 Identities = 51/157 (32%), Positives = 87/157 (55%), Gaps = 8/157 (5%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKF 190 E +KV+ ITG G+G + LL+ G K +A+ D+ E G+S +L+ ++G + F Sbjct: 2 EISNKVIIITGGVGGMGFETAKALLNHGAKFVALFDLTETDGQSAIEKLDKEFGKGRAGF 61 Query: 191 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALI------ 352 Y D+ + F N ++++ G IDV+INNA + N+ ++ + VNV + I Sbjct: 62 YPGDIVIDSEFEDNFNRIIKDHGSIDVLINNAGIANEQ--NIERLVNVNVVSSIDKNILR 119 Query: 353 -TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVM 460 + L A+ MGKH GGKGG ++NV+++ L ++ Sbjct: 120 ASQILLALNHMGKHKGGKGGAIVNVNAILGLIDCPIL 156 >UniRef50_UPI00015B42E2 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 266 Score = 96.3 bits (229), Expect = 3e-19 Identities = 51/147 (34%), Positives = 86/147 (58%), Gaps = 3/147 (2%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQV--ELNSKYG-NKTKF 190 KDKV +TG GIG + V+ LL G K++AI D+ ++ ++ ++G +K F Sbjct: 4 KDKVAIVTGGTGGIGFATVQALLRHGAKYVAIFDLDSMHTRAASCIHKVEEEFGKDKADF 63 Query: 191 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 370 Y DVT + F + +V Q +D+++N A++ ++ + I++N+TA++T TL Sbjct: 64 YTCDVTIQSEFAARYDEIVGMQRTVDILVNYASIASEPRAHHM--IDINLTAVVTCTLIG 121 Query: 371 IEIMGKHSGGKGGTVINVSSVAALTQS 451 I+ MG+H G+GG ++NV SV LT S Sbjct: 122 IDRMGRHHNGRGGAIVNVCSVFGLTTS 148 >UniRef50_UPI000051334A Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1) isoform 1; n=1; Apis mellifera|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1) isoform 1 - Apis mellifera Length = 264 Score = 95.9 bits (228), Expect = 4e-19 Identities = 45/140 (32%), Positives = 82/140 (58%), Gaps = 1/140 (0%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 202 K+ +TG A GIG R LL G K +A+LD+++ G+S +LN+++G ++ F D Sbjct: 6 KIAIVTGGANGIGFCTARKLLRNGAKAVALLDLSDSGGESAAADLNNEFGKDRAIFIACD 65 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 382 V+ E F V+ +++++N A +M+D+ ++ +++N ++ T+ + M Sbjct: 66 VSKNEQFQESFKKVIDTYETLNILVNIAGIMDDA--DWEIMVDINYKGIVYGTILGLHTM 123 Query: 383 GKHSGGKGGTVINVSSVAAL 442 GK+ GG GG ++N+SSVA L Sbjct: 124 GKYKGGNGGIIVNMSSVAGL 143 >UniRef50_P15428 Cluster: 15-hydroxyprostaglandin dehydrogenase [NAD+]; n=29; Euteleostomi|Rep: 15-hydroxyprostaglandin dehydrogenase [NAD+] - Homo sapiens (Human) Length = 266 Score = 94.7 bits (225), Expect = 9e-19 Identities = 49/140 (35%), Positives = 84/140 (60%), Gaps = 1/140 (0%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 202 KV +TGAA GIG + LL +G K +A++D EAG + L+ ++ KT F + D Sbjct: 6 KVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 382 V D++ VV G +D+++NNA + N+ ++K +++N+ ++I+ T ++ M Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKN--WEKTLQINLVSVISGTYLGLDYM 122 Query: 383 GKHSGGKGGTVINVSSVAAL 442 K +GG+GG +IN+SS+A L Sbjct: 123 SKQNGGEGGIIINMSSLAGL 142 >UniRef50_UPI00015B5FC8 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 267 Score = 92.7 bits (220), Expect = 4e-18 Identities = 52/147 (35%), Positives = 88/147 (59%), Gaps = 4/147 (2%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE---EAGKSLQVELNSKYGNKT 184 E K+KV +TG GIG V+ L+ ++ +AI+D+ + EA + +LN ++G + Sbjct: 2 EIKNKVAIVTGGIGGIGLVTVQHLIRSKIQFVAIIDLPKSDSEAAVANLSKLNKEFGKGS 61 Query: 185 -KFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 361 ++Y D+T+ + F I V+ + +D++IN A ++ND+ I VN TA++ S+ Sbjct: 62 YQYYSCDLTNIQEFRAIYEKVIALKKYVDILINAAGILNDNA--MNLCINVNFTAVVNSS 119 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAAL 442 + AIE M K GGKGG V+NV+S+A + Sbjct: 120 MIAIEHMRKDKGGKGGVVVNVASIAGI 146 >UniRef50_Q7PY55 Cluster: ENSANGP00000013280; n=4; Endopterygota|Rep: ENSANGP00000013280 - Anopheles gambiae str. PEST Length = 183 Score = 91.1 bits (216), Expect = 1e-17 Identities = 51/142 (35%), Positives = 77/142 (54%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K+KV +TGAATG+G + LL G K + I D+ +AG+ EL +YG + F Sbjct: 4 KNKVALVTGAATGLGRAFSEELLKHGAK-VVICDLDSDAGELTVEELEKQYGARVLFCHC 62 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 379 DVTD F V +++VINNA +MND+ ++ ++VN+ I TL A + Sbjct: 63 DVTDYIQFEEAFEYTVNMFKEVNIVINNAEIMNDN--FWELEVDVNLNGAIRGTLLAQKF 120 Query: 380 MGKHSGGKGGTVINVSSVAALT 445 M K G GG ++N+ S ++T Sbjct: 121 MDKSKGKGGGVLVNIGSGVSVT 142 >UniRef50_A6YPS8 Cluster: Oxidoreductase; n=1; Triatoma infestans|Rep: Oxidoreductase - Triatoma infestans (Assassin bug) Length = 252 Score = 88.6 bits (210), Expect = 6e-17 Identities = 55/146 (37%), Positives = 85/146 (58%), Gaps = 6/146 (4%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 196 WKD+V +TGA+ GIGE++ R L + G+K +A L + + LQ + N+ G+ K Y+ Sbjct: 4 WKDRVAVVTGASAGIGEAIARALAEHGMK-VAALARRLDRLQKLQDDCNNFIGS-IKPYK 61 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-----MND-SIGIYKKAIEVNVTALITS 358 DVT+E + ++V + G I V++NNA L M D S G ++ E NV L+T Sbjct: 62 CDVTNETEIATTIKSIVSDLGPISVLVNNAGLYENVPMTDTSQGSCRQTYETNVIGLVTF 121 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVA 436 T +EIM KH+ G +IN++S+A Sbjct: 122 TQHVVEIMKKHN-ITDGHIININSLA 146 >UniRef50_UPI0000D57364 Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1); n=1; Tribolium castaneum|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase [NAD+] (PGDH) (Prostaglandin dehydrogenase 1) - Tribolium castaneum Length = 312 Score = 87.8 bits (208), Expect = 1e-16 Identities = 46/142 (32%), Positives = 80/142 (56%), Gaps = 1/142 (0%) Frame = +2 Query: 29 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 205 V ITG A GIG ++ R+ L G+ +A+ D ++E G+ +L ++G NK F+ D+ Sbjct: 54 VAIITGGAEGIGLAIARVFLKCGISGLAVADCSKEKGEESIKQLACEFGENKVLFFDGDM 113 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 385 + + F + + +++V+NNA +MND ++ + N++ I TL ++ M Sbjct: 114 SQSKAFDRVFKETLNHFENVNIVVNNAGVMNDV--NWECQVNTNLSGTIIGTLLGMQYMS 171 Query: 386 KHSGGKGGTVINVSSVAALTQS 451 K S G+GGT+INV+S+ L S Sbjct: 172 KTSLGQGGTIINVASIMGLIPS 193 >UniRef50_UPI00015B5A58 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 263 Score = 87.4 bits (207), Expect = 1e-16 Identities = 50/144 (34%), Positives = 84/144 (58%), Gaps = 3/144 (2%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKS-LQVE-LNSKYGN-KTKF 190 K+KV+ ITG G+ + ++LL ++IA+ D E+ + LQ++ ++G + F Sbjct: 4 KNKVIIITGGLGGLATATTQVLLKHEPRYIALFDTEEKNSYAELQLKKFEQEFGEGRVGF 63 Query: 191 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 370 Y SDV ++ F + V++ +D++IN A ++ D+ + I+VN L+ TL A Sbjct: 64 YASDVRNQHQFEEKYDQVLKSHKSVDILINLAGILCDADT--ELTIDVNFKGLVFCTLTA 121 Query: 371 IEIMGKHSGGKGGTVINVSSVAAL 442 I+ MG H GG+GGT+INVSS+ L Sbjct: 122 IDKMGIHRGGRGGTIINVSSIVGL 145 >UniRef50_UPI0000D57365 Cluster: PREDICTED: similar to CG4899-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG4899-PA, isoform A - Tribolium castaneum Length = 295 Score = 87.0 bits (206), Expect = 2e-16 Identities = 48/137 (35%), Positives = 72/137 (52%), Gaps = 1/137 (0%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 202 KV ITG + GIG +V +L E K++A++ + G+ LNS YG NK F+ D Sbjct: 52 KVALITGGSDGIGLAVAHEILSENSKNVALIGVDNTKGRESVHALNSTYGRNKAVFFNCD 111 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 382 V + N V++E G ID+VIN A + + ++K I N+ I TL+A +M Sbjct: 112 VESKVQVNDCFNKVIKEFGSIDIVINAAGVFDGR--CWEKEIMTNLVGTIHCTLEAYRVM 169 Query: 383 GKHSGGKGGTVINVSSV 433 K G GG ++N S + Sbjct: 170 SKDCSGSGGVILNFSGL 186 >UniRef50_Q5P8S6 Cluster: Putative dehydrogenase; n=4; Proteobacteria|Rep: Putative dehydrogenase - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 267 Score = 83.8 bits (198), Expect = 2e-15 Identities = 50/146 (34%), Positives = 80/146 (54%), Gaps = 7/146 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +++GAA+GIG ++ R+ EG + + D+ E G+++ + + G + F DV Sbjct: 8 KVAYVSGAASGIGAAIARVFAAEGAS-VLLGDVQVERGETVAAHIREQ-GGRALFIHHDV 65 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLK 367 +DE + L V+E GG+D+++NNA L + + K + VNV +I Sbjct: 66 SDERQWESALACAVEEFGGMDLLVNNAGIEQTGLLADVELADINKLLAVNVAGVILGHKH 125 Query: 368 AIEIMGK-HSGGKGGTVINVSSVAAL 442 AI M S GKGG++IN+SSVA L Sbjct: 126 AIRTMRPGGSAGKGGSIINLSSVAGL 151 >UniRef50_Q9ABI1 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=7; Alphaproteobacteria|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Caulobacter crescentus (Caulobacter vibrioides) Length = 261 Score = 83.4 bits (197), Expect = 2e-15 Identities = 49/146 (33%), Positives = 80/146 (54%), Gaps = 7/146 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-YRSD 202 K FITG A G+G + R+L EG K +A+ DI +++ E+N+ +G T F + D Sbjct: 11 KKAFITGGAQGLGAAAGRMLAKEGAK-VALADINLAGAQAVADEINAAHGAGTAFAFELD 69 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTL 364 VT E+ ++ +L GG+ V++NNA + D G++KK + VNV ++ Sbjct: 70 VTQEDQWIDVLEKATAAMGGLSVLVNNAGIGGDGPIESLDFGLWKKVMSVNVDSVFLGAK 129 Query: 365 KAIEIMGKHSGGKGGTVINVSSVAAL 442 A+ M H + G++IN+SS+A L Sbjct: 130 HALTHMRAH---QPGSIINLSSIAGL 152 >UniRef50_Q1HPX6 Cluster: Alcohol dehydrogenase; n=1; Bombyx mori|Rep: Alcohol dehydrogenase - Bombyx mori (Silk moth) Length = 289 Score = 83.0 bits (196), Expect = 3e-15 Identities = 55/142 (38%), Positives = 77/142 (54%), Gaps = 2/142 (1%) Frame = +2 Query: 11 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTK 187 +E + KVV ITGAA GIG ++ L G K I ILDI G ELN KYG NK + Sbjct: 29 NEIEGKVVVITGAAQGIGYAIADNFLKNGAKVIIILDINVPKGIQAAKELNCKYGKNKAE 88 Query: 188 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 367 F D+T + I + ++ +DV++NNA + + +K + N A I +LK Sbjct: 89 FIECDITKD--LERISKIIYKKYKYVDVLVNNAGIFKEIKP--RKLLLTNAVATIEFSLK 144 Query: 368 AIEIMGKHS-GGKGGTVINVSS 430 +E M K GKGGT+IN++S Sbjct: 145 FMENMRKDKLSGKGGTIINIAS 166 >UniRef50_Q6C6W8 Cluster: Similar to tr|Q9WYD3 Thermotoga maritima TM0297 Oxidoreductase; n=7; Ascomycota|Rep: Similar to tr|Q9WYD3 Thermotoga maritima TM0297 Oxidoreductase - Yarrowia lipolytica (Candida lipolytica) Length = 291 Score = 83.0 bits (196), Expect = 3e-15 Identities = 48/143 (33%), Positives = 80/143 (55%), Gaps = 6/143 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TG A G+G S+ L G+K IAILD+ ++ G +L+ YG + +FY++DV Sbjct: 46 KVAIVTGGARGLGFSMAEGLCSVGLKGIAILDVQQDLGLDAIEKLHKAYGVQAQFYKADV 105 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 367 DEE I++ VV + G +DVV+N+A + + +++ I++N+ T Sbjct: 106 RDEESVNEIIDRVVHDLGSVDVVVNSAGVADLVHAAEYPADKFRRVIDINLNGSFLVTQA 165 Query: 368 AIEIMGKHSGGKGGTVINVSSVA 436 A M K G GGTV+ ++S++ Sbjct: 166 AARHMIKQ--GTGGTVVFIASMS 186 >UniRef50_UPI00015B572C Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=2; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 268 Score = 81.0 bits (191), Expect = 1e-14 Identities = 47/145 (32%), Positives = 79/145 (54%), Gaps = 5/145 (3%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIA----EEAGKSLQVELNSKYG-NKTK 187 +KV +TG GIG +V+ L G K +AI D+ EE +L+ +L ++ + Sbjct: 5 NKVGVVTGGLRGIGYVIVQHFLRRGAKFVAIFDLDVEEHEEVVNALK-QLEQEFAAQRFS 63 Query: 188 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK 367 +Y DVT+ + F+ + V G +D+++NNA + + + VN T++I T+ Sbjct: 64 YYCCDVTNFKKFIACYDEVYTTNGAVDILVNNAGVFAEHD--QDLTVAVNFTSVIHCTMH 121 Query: 368 AIEIMGKHSGGKGGTVINVSSVAAL 442 AIE MG + GGKGG ++ + S+ AL Sbjct: 122 AIERMGTNKGGKGGVIVTIGSICAL 146 >UniRef50_UPI00015B5317 Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 337 Score = 80.2 bits (189), Expect = 2e-14 Identities = 41/135 (30%), Positives = 73/135 (54%), Gaps = 1/135 (0%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSD 202 K V ITG A G+G + L G I I+DI + AGK + + +G K F +D Sbjct: 46 KNVLITGGAAGLGHAFFNHFLQFGANKICIIDIDDVAGKKIVASTDKSHGVGKVIFIHAD 105 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 382 V+ + V+ +D+V+NNA ++++ +++ I VN+ +I+ L +++ M Sbjct: 106 VSRHSEIVAGFQKAVKLMDAVDIVVNNAGILDER--RWEREIAVNLNGMISVALLSMQYM 163 Query: 383 GKHSGGKGGTVINVS 427 G+ GG+GG ++NV+ Sbjct: 164 GRDMGGRGGILVNVA 178 >UniRef50_Q9VV42 Cluster: CG4899-PA, isoform A; n=5; Sophophora|Rep: CG4899-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 278 Score = 79.8 bits (188), Expect = 3e-14 Identities = 47/143 (32%), Positives = 79/143 (55%), Gaps = 1/143 (0%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKT-KFY 193 ++ K +TG A GIG V + LL G +AI+D+ + + V+L + + ++ Sbjct: 20 FRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEF--VKLRAAHPTQSVMII 77 Query: 194 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 373 + DV +++ + + G ID+V+N A + ND ++ + VN+ +I STL A+ Sbjct: 78 KMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKD--VQRTLLVNLGGIINSTLSAL 135 Query: 374 EIMGKHSGGKGGTVINVSSVAAL 442 MGK +GGKGG V+N+SSV L Sbjct: 136 PYMGKDNGGKGGIVVNMSSVVGL 158 >UniRef50_Q8U3B3 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=3; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Pyrococcus furiosus Length = 260 Score = 79.4 bits (187), Expect = 4e-14 Identities = 47/147 (31%), Positives = 80/147 (54%), Gaps = 6/147 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K+KV +TG GIG ++ ++ + G K + + +I EEAG + L + G F ++ Sbjct: 7 KNKVAIVTGGGQGIGAAIAQLFAENGAK-VVLAEIDEEAGLEREAMLRER-GLDVTFIKT 64 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITST 361 DV DEE ++ V+ GG+D+++NNAA+M+ ++ +++ I VN+T + Sbjct: 65 DVADEESVKNMVKKTVELYGGVDILVNNAAIMSVKSIFERTLEEWERVIRVNLTGPYICS 124 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAAL 442 A E M K GG +IN++S AL Sbjct: 125 RYAAEEMIKRG---GGVIINIASTRAL 148 >UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to hydroxyprostaglandin dehydrogenase 15 (NAD); n=2; Tribolium castaneum|Rep: PREDICTED: similar to hydroxyprostaglandin dehydrogenase 15 (NAD) - Tribolium castaneum Length = 479 Score = 79.0 bits (186), Expect = 5e-14 Identities = 42/142 (29%), Positives = 81/142 (57%), Gaps = 2/142 (1%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKFYRS 199 +KV I+GAA+GIG ++ + LL G++ + I D+ +E G+ E+ +++G+ + F + Sbjct: 7 NKVALISGAASGIGLTIAKELLRNGLRGVTIADVNKELGEKALQEIENEFGSGRAIFVLT 66 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE- 376 DV+ + F + ID+++N A ++NDS I+++ I +NV + L A+E Sbjct: 67 DVSSMKSFEDAFQKTINTFKNIDILVNGAGVLNDS--IWQQEIAINVNGTVHGILLALEN 124 Query: 377 IMGKHSGGKGGTVINVSSVAAL 442 + K+ G ++N SS+A + Sbjct: 125 YIPKYKTDSEGVIVNFSSIAGV 146 Score = 58.4 bits (135), Expect = 7e-08 Identities = 32/126 (25%), Positives = 67/126 (53%), Gaps = 2/126 (1%) Frame = +2 Query: 71 VVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDVTDEEHFLGILNAVV 247 +VR G + I DI E G+ + E+ +++G NK + +DVT + + + Sbjct: 233 IVRNAPSGGAWGVTIADINTELGEKVLQEIINEFGKNKAIYILTDVTCKNSYEAAFKKTI 292 Query: 248 QEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE-IMGKHSGGKGGTVINV 424 + +D+V+N A ++N+ +++ +++N+ + T+ A+E + K+ G G ++N+ Sbjct: 293 ETFQNLDIVVNGAGIVNEL--DWQQEVDINLNGTLHGTILALENYIPKYKSGSEGVIVNI 350 Query: 425 SSVAAL 442 SS A L Sbjct: 351 SSAAIL 356 >UniRef50_A6C9B3 Cluster: Probable putative oxidoreductase; n=1; Planctomyces maris DSM 8797|Rep: Probable putative oxidoreductase - Planctomyces maris DSM 8797 Length = 270 Score = 78.2 bits (184), Expect = 8e-14 Identities = 48/149 (32%), Positives = 76/149 (51%), Gaps = 3/149 (2%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 196 ++D+VV +TG + GIGE R+ EG H+AIL AG+ L ELN K F + Sbjct: 18 FQDRVVIVTGGSKGIGEGCSRVFCAEG-GHVAILARGLHAGQDLARELNETGPGKAMFVQ 76 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTAL---ITSTLK 367 DV + E ++ VV++ G +D +INNA + ++ + + +IE + ST Sbjct: 77 CDVGEHEQIRSAIDLVVEQFGRLDCIINNAGVHPPAMSLEETSIEEMEQLMRVNFLSTFA 136 Query: 368 AIEIMGKHSGGKGGTVINVSSVAALTQSH 454 + H GT+IN+SS+ A+ H Sbjct: 137 GAKYALPHLRKTKGTIINMSSMTAVLGQH 165 >UniRef50_A7HWF2 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Parvibaculum lavamentivorans DS-1 Length = 268 Score = 77.0 bits (181), Expect = 2e-13 Identities = 46/148 (31%), Positives = 79/148 (53%), Gaps = 9/148 (6%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TGAA GIG + + L EG K + D E G+ + E+ + G T F+R DV Sbjct: 7 KVAIVTGAAKGIGAATAKALAREGAK-VVCSDFDAENGQVVADEIAGEGGTAT-FFRHDV 64 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITSTL 364 TDE + ++ ++ GG+ VV+NNA + + ++ ++ IEV++ ++ Sbjct: 65 TDEAQWEAVVKLAEEKFGGLHVVVNNAGIAPEAGPIEEKTLADWRHTIEVDLDSVFLGCK 124 Query: 365 KAIEIMGKHS--GGKGGTVINVSSVAAL 442 I + K++ GG GG ++N+SS+ L Sbjct: 125 HGIRTIKKYTSKGGAGGAIVNISSILGL 152 >UniRef50_Q8EXX5 Cluster: 3-ketoacyl-acyl carrier protein reductase; n=7; Bacteria|Rep: 3-ketoacyl-acyl carrier protein reductase - Leptospira interrogans Length = 254 Score = 75.8 bits (178), Expect = 4e-13 Identities = 48/147 (32%), Positives = 79/147 (53%), Gaps = 6/147 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K K +TGAA GIG+S L G ++ I D+ EE+ K+ E++ + G K + Sbjct: 5 KGKNAVVTGAARGIGKSTALTLAKAGA-NLVIADLNEESSKATADEISKQTGVKAIGIGT 63 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK------AIEVNVTALITST 361 +V+D + + A V E G +D+++NNA + D++ + K I VN+T T Sbjct: 64 NVSDVDSAAKAIQACVDEFGSVDILVNNAGITKDTLLMRMKKEQWDAVIAVNLTGTFNCT 123 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAAL 442 AI+ M K+ GG++IN+SS+A + Sbjct: 124 QAAIKFMMKNP--NGGSIINLSSIAGV 148 >UniRef50_A3Q331 Cluster: Short-chain dehydrogenase/reductase SDR; n=10; Mycobacterium|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain JLS) Length = 282 Score = 75.4 bits (177), Expect = 6e-13 Identities = 44/151 (29%), Positives = 80/151 (52%), Gaps = 8/151 (5%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 193 E + +V +TG A+GIG V + EG K + I D+ +E G++L + G F+ Sbjct: 8 ELQGRVAIVTGGASGIGRGVAERFVAEGAK-VVIADVQDELGEALAEQC----GPNALFH 62 Query: 194 RSDVTDEEHFLGILNAVVQEQGGIDVVINNA--------ALMNDSIGIYKKAIEVNVTAL 349 +DV D+E +++ V+ G +DV++NNA L N+ + + + + VN+ ++ Sbjct: 63 HTDVGDQEQMRRLVDVAVERFGALDVMVNNAGISSPLRRGLFNEDLEEFDRVMRVNLLSV 122 Query: 350 ITSTLKAIEIMGKHSGGKGGTVINVSSVAAL 442 + T A M +H GG++IN+SS+ + Sbjct: 123 MAGTRDAGRYMSEHG---GGSIINLSSIGGI 150 >UniRef50_UPI0000D5767E Cluster: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase; n=2; Tribolium castaneum|Rep: PREDICTED: similar to 15-hydroxyprostaglandin dehydrogenase - Tribolium castaneum Length = 255 Score = 74.9 bits (176), Expect = 8e-13 Identities = 46/144 (31%), Positives = 80/144 (55%), Gaps = 1/144 (0%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 193 E K KV +TG A+GIG ++VR LL G+K ++++DI+E EL ++ F Sbjct: 3 ELKGKVALVTGGASGIGLAMVRELLKNGIKAVSVVDISE------NTELQD---SRVTFI 53 Query: 194 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 373 ++DVT ++ + V +D+V+NNA ++ D I +K+ I++N+ A+I T A+ Sbjct: 54 KTDVTCKKQLQAAFDKTVATYNQLDIVVNNAGVI-DEID-WKRTIDINLVAVIEGTYLAL 111 Query: 374 E-IMGKHSGGKGGTVINVSSVAAL 442 + K+ G ++N +SV L Sbjct: 112 RTYLPKYKSEAEGVIVNTASVLGL 135 >UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase family protein; n=4; cellular organisms|Rep: Short-chain dehydrogenase/reductase family protein - Gramella forsetii (strain KT0803) Length = 249 Score = 74.5 bits (175), Expect = 1e-12 Identities = 48/146 (32%), Positives = 76/146 (52%), Gaps = 6/146 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K K + ITGA++GIGE+ L EGV ++ + EE K L+ +++ + G K Sbjct: 4 KGKTIIITGASSGIGEATAMRLAKEGV-NVVLTARREEKLKELKSKIDKENGGKALVIPG 62 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITST 361 DVT +E F +++ +E G ID +INNA LM N + K ++VN+ ++ Sbjct: 63 DVTKKEDFKNLIDKTKKEFGSIDGLINNAGLMPLSYVKNLHTDEWDKMVDVNIKGVLNGV 122 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAA 439 + M + K G +IN+SS AA Sbjct: 123 AAVLPTMMEQ---KSGNIINISSSAA 145 >UniRef50_Q6XPZ7 Cluster: Short-chain dehydrogenase/reductase; n=1; Apis mellifera|Rep: Short-chain dehydrogenase/reductase - Apis mellifera (Honeybee) Length = 246 Score = 74.1 bits (174), Expect = 1e-12 Identities = 45/148 (30%), Positives = 81/148 (54%), Gaps = 6/148 (4%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 196 W D+V +TGA +GIG+ ++ L+ +G+K I I ++ K+L EL SK G K + Sbjct: 5 WIDEVALVTGANSGIGKCLIECLVGKGMKVIGIAPQVDKM-KTLVEELKSKPG-KLVPLQ 62 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITS 358 D++++ L ++ V + G ID++INNA L ND + +KK ++N+ L Sbjct: 63 CDLSNQNDILKVIEWVEKNLGAIDILINNATINIDVTLQNDEVLDWKKIFDINLLGLTCM 122 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVAAL 442 + +++M K G G ++N++ + L Sbjct: 123 IQEVLKLM-KKKGINNGIIVNINDASGL 149 >UniRef50_A7SGX6 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 266 Score = 74.1 bits (174), Expect = 1e-12 Identities = 47/145 (32%), Positives = 74/145 (51%), Gaps = 7/145 (4%) Frame = +2 Query: 29 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYRSDV 205 V +TG GIG ++ + LLD K + +LDI E+ G L+ Y ++ F + DV Sbjct: 7 VAIVTGGVQGIGLAISKALLDRDGK-VCMLDINEKTGNETLKLLSENYSKHRVLFIKCDV 65 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALM---NDSI--GIYKKAIEVNVTALITSTLKA 370 T + G +D++ NNA + ND + G +K I++NV +I TL Sbjct: 66 TSQPQMEAAFQRTKDVFGRLDILCNNAGIAVRENDLLRSGAWKTIIDINVKGVILGTLLG 125 Query: 371 IEIMGKHSG-GKGGTVINVSSVAAL 442 ++ MG G GGT++NV+S+A L Sbjct: 126 LDHMGVSGAKGHGGTIVNVASLAGL 150 >UniRef50_Q396I7 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 258 Score = 73.7 bits (173), Expect = 2e-12 Identities = 45/142 (31%), Positives = 78/142 (54%), Gaps = 3/142 (2%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TG A G+G + R+ + EG + I D+ + G++L EL G+ +F R DV Sbjct: 7 KVAIVTGGARGMGAATCRLFVAEGAC-VVIGDVLDAEGEALAREL----GDAARFMRLDV 61 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGIYKKAIEVNVTALITSTLKAIEI 379 DE +++ + +A +++ G IDV++NNAA++ + K+ E V+ + T I Sbjct: 62 ADEANWVRVTDATMEQFGRIDVLVNNAAVLTFGGITELSKRDFERAVSINLVGTFVGIRT 121 Query: 380 MGKHS-GGKGGTVINVSSVAAL 442 + H K G+++N+SSV L Sbjct: 122 IAPHMIAQKSGSIVNISSVDGL 143 >UniRef50_Q28GY1 Cluster: Novel protein containing short chain dehydrogenase domain; n=4; Deuterostomia|Rep: Novel protein containing short chain dehydrogenase domain - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 255 Score = 73.3 bits (172), Expect = 2e-12 Identities = 49/146 (33%), Positives = 77/146 (52%), Gaps = 7/146 (4%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-Y 193 WK +V +TGA+ GIG +V R+L+ G+K + ++ K L E S T F Y Sbjct: 4 WKGRVALVTGASVGIGAAVARVLVQHGMKVVGCARSVDKIEK-LAAECQSAGYPGTLFPY 62 Query: 194 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALIT 355 + D+++EE L + +A+ G+DV INNA L++ ++ I+VNV AL Sbjct: 63 KCDLSNEEEILSMFSAIKTLHQGVDVCINNAGLARPEPLLSGKTEGWRTMIDVNVLALSI 122 Query: 356 STLKAIEIMGKHSGGKGGTVINVSSV 433 T +A + M K G +IN++SV Sbjct: 123 CTREAYQSM-KERNIDDGHIININSV 147 >UniRef50_Q1GNJ2 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Sphingomonadales|Rep: Short-chain dehydrogenase/reductase SDR - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 285 Score = 73.3 bits (172), Expect = 2e-12 Identities = 49/143 (34%), Positives = 72/143 (50%), Gaps = 4/143 (2%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TGAA+GIG++ V L EG H+ DI E G++L N + F R DV Sbjct: 6 KVAVVTGAASGIGKATVLKLAGEGA-HVFAADIDEAGGRALADASNGRID----FVRCDV 60 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK---KAIEVNVTALITSTLKAIE 376 T +++A + GGID+V NNAA D I + + + + ++ S I Sbjct: 61 TVPSDIEALMDAAAAKAGGIDIVFNNAAAGGDRAPIDEITPEGWDATMDLVLKSVAMGIR 120 Query: 377 IMGKH-SGGKGGTVINVSSVAAL 442 H G KG +++N +SVAAL Sbjct: 121 YAAPHMKGRKGASIVNTASVAAL 143 >UniRef50_Q6UWP2 Cluster: Dehydrogenase/reductase SDR family member 11 precursor; n=30; Euteleostomi|Rep: Dehydrogenase/reductase SDR family member 11 precursor - Homo sapiens (Human) Length = 260 Score = 73.3 bits (172), Expect = 2e-12 Identities = 48/149 (32%), Positives = 79/149 (53%), Gaps = 9/149 (6%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--KSLQVELNSK-YGNKTK 187 W+D++ +TGA+ GIG +V R L+ +G+K ++ A G + L E S Y Sbjct: 9 WRDRLALVTGASGGIGAAVARALVQQGLK---VVGCARTVGNIEELAAECKSAGYPGTLI 65 Query: 188 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTAL 349 YR D+++EE L + +A+ + G+D+ INNA L++ S +K VNV AL Sbjct: 66 PYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLAL 125 Query: 350 ITSTLKAIEIMGKHSGGKGGTVINVSSVA 436 T +A + M K G +IN++S++ Sbjct: 126 SICTREAYQSM-KERNVDDGHIININSMS 153 >UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacteria|Rep: Cyclopentanol dehydrogenase - Comamonas sp. (strain NCIMB 9872) Length = 250 Score = 72.9 bits (171), Expect = 3e-12 Identities = 46/146 (31%), Positives = 75/146 (51%), Gaps = 6/146 (4%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 202 DKVV +TG A G+G + +L EG + + D+ EE G E+ + G K F D Sbjct: 6 DKVVLVTGGAMGMGLTHCTLLAREGAT-VYLSDMNEELGHQAVAEIR-RQGGKAHFLHLD 63 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 364 VT+E H+ G ++ ++ E +D ++NNA ++ + S + + E+NV ++ T Sbjct: 64 VTNENHWTGAVDTILAESDRLDALVNNAGILTLKPVQDTSNEEWDRIFEINVRSVFLGTR 123 Query: 365 KAIEIMGKHSGGKGGTVINVSSVAAL 442 IE M K G ++NVSS+ L Sbjct: 124 AVIEPMRK---AHKGCIVNVSSIYGL 146 >UniRef50_P19871 Cluster: 3-beta-hydroxysteroid dehydrogenase; n=4; Burkholderiales|Rep: 3-beta-hydroxysteroid dehydrogenase - Comamonas testosteroni (Pseudomonas testosteroni) Length = 254 Score = 72.9 bits (171), Expect = 3e-12 Identities = 45/144 (31%), Positives = 81/144 (56%), Gaps = 6/144 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TG A+G+G VV++LL EG K +A DI E AG+ L EL G ++ F R DV Sbjct: 8 KVALVTGGASGVGLEVVKLLLGEGAK-VAFSDINEAAGQQLAAEL----GERSMFVRHDV 62 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTLK 367 + E + ++ AV + G ++V++NNA ++ + + + +++N ++ + Sbjct: 63 SSEADWTLVMAAVQRRLGTLNVLVNNAGILLPGDMETGRLEDFSRLLKINTESVFIGCQQ 122 Query: 368 AIEIMGKHSGGKGGTVINVSSVAA 439 I M + GG++IN++SV++ Sbjct: 123 GIAAMKE----TGGSIINMASVSS 142 >UniRef50_Q7M9W0 Cluster: 3-OXOACYL-REDUCTASE; n=24; Epsilonproteobacteria|Rep: 3-OXOACYL-REDUCTASE - Wolinella succinogenes Length = 247 Score = 72.1 bits (169), Expect = 5e-12 Identities = 41/146 (28%), Positives = 75/146 (51%), Gaps = 6/146 (4%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 193 ++ K V ITG++ GIG + R+L + G+K L+ E+ +K G + Sbjct: 2 KFSGKNVLITGSSRGIGADIARVLAEMGLKVWINYRSQSSLADELKAEIEAK-GGQAAVI 60 Query: 194 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALIT 355 D TDEE F+ + ++ G + ++NNA + ND + I ++ IE N+T+ Sbjct: 61 SFDATDEEAFISGIKTIIDADGELAYLVNNAGITNDKLAIRMKTEEFRSVIEANLTSAFI 120 Query: 356 STLKAIEIMGKHSGGKGGTVINVSSV 433 + +A++ M K + G+V+N+SS+ Sbjct: 121 GSREALKSMSKQ---RFGSVVNISSI 143 >UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Flavobacterium johnsoniae UW101|Rep: Short-chain dehydrogenase/reductase SDR - Flavobacterium johnsoniae UW101 Length = 269 Score = 72.1 bits (169), Expect = 5e-12 Identities = 48/146 (32%), Positives = 78/146 (53%), Gaps = 6/146 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKY-GNKTKFYR 196 KDK + ITG TGIG+++ +L+ G + + I E+ K+ ++ ++ G++ Sbjct: 30 KDKKIVITGGTTGIGKAIADVLVSLGGR-VLIFGRDEKDFKNAVADIQKQFPGSEVYGTP 88 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL-----MNDSIGIYKKAIEVNVTALITST 361 +DVT +E IL E GGID++INNAAL N+S YK I+ N+T + Sbjct: 89 ADVTKKEDIQKILEIADNELGGIDILINNAALGAPGITNESYDDYKYIIDTNITGYLAFA 148 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAA 439 +A M + K G +IN+ S++A Sbjct: 149 QEAASRMKQQ---KSGHIINIGSMSA 171 >UniRef50_A0QDR7 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=2; Actinomycetales|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Mycobacterium avium (strain 104) Length = 250 Score = 72.1 bits (169), Expect = 5e-12 Identities = 44/143 (30%), Positives = 80/143 (55%), Gaps = 4/143 (2%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TGAA+GIGE+ + L ++G K + + DI E+ G+ + E+ ++ G + F R+D+ Sbjct: 6 KVAVVTGAASGIGEATAKRLAEDGAK-VVVADINEDGGERVVAEI-AERGGEAAFLRTDI 63 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEV--NVTAL-ITSTLKAIE 376 + EE +++ V GG+ + NNAA+ + +++ + +V VT + + T + Sbjct: 64 SIEEDVNSLIDFAVSTYGGLHLAHNNAAVAHTPTPLHELSTDVFDTVTGIGLRGTFFCMR 123 Query: 377 IMGKHS-GGKGGTVINVSSVAAL 442 H G GG ++N +S AAL Sbjct: 124 AEIAHMIGHGGGAIVNTASGAAL 146 >UniRef50_Q2NIC9 Cluster: Predicted short chain dehydrogenase; n=2; Euryarchaeota|Rep: Predicted short chain dehydrogenase - Methanosphaera stadtmanae (strain DSM 3091) Length = 253 Score = 71.7 bits (168), Expect = 7e-12 Identities = 47/148 (31%), Positives = 76/148 (51%), Gaps = 7/148 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K KV ITGA GIG+S+ + +EG I I E + + E+NS G+ + Sbjct: 4 KGKVAIITGATAGIGKSIAYLFAEEGASTILIARRKERL-EQITNEINSNGGDASACI-G 61 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 358 DVT +E ++ + + G ID+++NNA +M+D + + + K I+VN+T + Sbjct: 62 DVTKQEDIDNVVKLALDKYGKIDIIVNNAGIMDDFVSVKHIDDDLWDKTIDVNLTGPMRL 121 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVAAL 442 I M K++ GG +I +SSV L Sbjct: 122 IRAVIPEMIKNN---GGNIITISSVGGL 146 >UniRef50_UPI00015B572E Cluster: PREDICTED: similar to putative alcohol dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to putative alcohol dehydrogenase - Nasonia vitripennis Length = 240 Score = 71.3 bits (167), Expect = 9e-12 Identities = 44/144 (30%), Positives = 75/144 (52%), Gaps = 4/144 (2%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQ---VELNSKYGN-KTKF 190 +KV +T GIG S + L +++A+LD+ + + L ++G K + Sbjct: 5 NKVAIVTDGLGGIGFSTYLLRLK--AQYVAVLDLPQNNSPHVVDGLKTLEEEFGKGKFGY 62 Query: 191 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKA 370 Y +V + E F + VV+ +G +D+++ NAA+ D+ I+VN+ +I TL A Sbjct: 63 YHVNVANAESFAAVYAKVVEHKGYVDILVYNAAVAKDTE--IDLTIDVNLKGVIKGTLHA 120 Query: 371 IEIMGKHSGGKGGTVINVSSVAAL 442 +E MG H KGG V+N++S L Sbjct: 121 VEQMGVHKNQKGGVVVNIASFLGL 144 >UniRef50_Q398I5 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 251 Score = 71.3 bits (167), Expect = 9e-12 Identities = 47/145 (32%), Positives = 76/145 (52%), Gaps = 6/145 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV ITG A G GE+ R + EG + + I D+ +EAG+ + EL G+ +F DV Sbjct: 7 KVALITGGARGQGEAEARRFVAEGAR-VVIADVLDEAGQRVAAEL----GDAARFQHLDV 61 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 367 T E + ++A + + G +D+++NNAA++ S+ Y+K I+VN Sbjct: 62 TREADWQIAVDATLAQFGRLDILVNNAAILKLVPIEACSLDDYRKVIDVNQVGCWLGMKS 121 Query: 368 AIEIMGKHSGGKGGTVINVSSVAAL 442 A +G GG+++NVSS A + Sbjct: 122 A---LGALKAAGGGSIVNVSSTAGM 143 >UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=3; Clostridium perfringens|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A) Length = 272 Score = 71.3 bits (167), Expect = 9e-12 Identities = 47/150 (31%), Positives = 79/150 (52%), Gaps = 7/150 (4%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 196 + DKV+ ITGAA GIG++V EG K + + D EE K E+ N +F Sbjct: 9 FSDKVMIITGAAGGIGKAVALRAAKEGAK-LVLADRKEEMSKETLKEIREITSN-VEFLI 66 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALIT 355 D+ + E+ +++ +++ GG+D++INNA + S +++ ++ N+ Sbjct: 67 CDLREGENCKKVIDTAIKKFGGLDILINNAGITGTPAPVHEMSEEMFRNVLDCNIMIAFH 126 Query: 356 STLKAIEIMGKHSGGKGGTVINVSSVAALT 445 + I+ M K + KGG ++NVSSVA LT Sbjct: 127 CSHYGIQEMIKQN--KGGAIVNVSSVAGLT 154 >UniRef50_A3XKE6 Cluster: Short-chain dehydrogenase/reductase SDR; n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Leeuwenhoekiella blandensis MED217 Length = 257 Score = 71.3 bits (167), Expect = 9e-12 Identities = 43/147 (29%), Positives = 79/147 (53%), Gaps = 6/147 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K+KV +TG A+G+G+S ++L EG K I + DI EE GK + V+ + G + F + Sbjct: 5 KNKVAIVTGGASGLGKSSAKLLAREGAK-IVVSDIDEEGGKKV-VQQIKEDGGEAIFIKQ 62 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL-----MND-SIGIYKKAIEVNVTALITST 361 DV E+ + ++ ++ G + ++ N+A + + D ++ +K I++N+ T Sbjct: 63 DVAKEDEWKNVIETTLETYGKLHILANSAGIGLGGTVEDVTLEDWKNLIDINLNGTFLGT 122 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAAL 442 I+ G +GG++IN SS+ L Sbjct: 123 KYGIK--GMRKTDEGGSIINFSSIEGL 147 >UniRef50_Q89M15 Cluster: Dehydrogenase; n=3; Proteobacteria|Rep: Dehydrogenase - Bradyrhizobium japonicum Length = 271 Score = 70.9 bits (166), Expect = 1e-11 Identities = 43/146 (29%), Positives = 80/146 (54%), Gaps = 7/146 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TG A+GIGE++V + EG IA D+ E G L + +K G K F DV Sbjct: 10 KVALVTGGASGIGEAIVELFAREGATVIA-TDVDELRGPELAKRI-TKAGGKAIFLEQDV 67 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNA-------ALMNDSIGIYKKAIEVNVTALITSTL 364 + EE ++ I+ + + G +D++++NA ++++ ++G ++K +N+ + S Sbjct: 68 SSEERWIEIVAEIAKRYGRLDIMVSNAGIGIAVPSIVDMTLGDWRKQNAINLDGVFLSVK 127 Query: 365 KAIEIMGKHSGGKGGTVINVSSVAAL 442 + +M K GG+++ +SS+A L Sbjct: 128 HCLPLMRKTG---GGSIVMMSSLAGL 150 >UniRef50_Q03906 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=3; Clostridium|Rep: 7-alpha-hydroxysteroid dehydrogenase - Eubacterium sp. (strain VPI 12708) Length = 266 Score = 70.9 bits (166), Expect = 1e-11 Identities = 41/151 (27%), Positives = 84/151 (55%), Gaps = 10/151 (6%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVK-HIAILDIAEEAGKSLQVELNSKYGNKTKFYR 196 KDKV+ +T + GIG ++ + EG K ++ ++ E K+ E+N+ GN K+ Sbjct: 4 KDKVILVTASTRGIGLAIAQACAKEGAKVYMGARNL--ERAKARADEMNAAGGN-VKYVY 60 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINN---------AALMNDSIGIYKKAIEVNVTAL 349 +D T EE ++ ++ +++++G IDV++NN + N ++ K + +N+ ++ Sbjct: 61 NDATKEETYVTMIEEIIEQEGRIDVLVNNFGSSNPKKDLGIANTDPEVFIKTVNINLKSV 120 Query: 350 ITSTLKAIEIMGKHSGGKGGTVINVSSVAAL 442 ++ A++ M ++ GG++IN+SSV L Sbjct: 121 FIASQTAVKYMAENG---GGSIINISSVGGL 148 >UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Methanospirillum hungatei JF-1|Rep: Short-chain dehydrogenase/reductase SDR - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 249 Score = 70.9 bits (166), Expect = 1e-11 Identities = 42/147 (28%), Positives = 80/147 (54%), Gaps = 6/147 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 ++KV+ +TG + GIG+++ DEG K + + EE+ K++ E++ K G+ ++ Sbjct: 6 ENKVLLVTGGSRGIGKAIALRCADEGAKVVITWESHEESAKNVVNEIHHKNGSAMAI-QA 64 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE------VNVTALITST 361 DV +E+ ++N + E G +D+++NNA +M +++ + K E N + Sbjct: 65 DVRNEDDVKKVINKIKGEYGRLDILVNNAGIMKNNLLLMTKTEEFDLLLATNCKGPFLYS 124 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAAL 442 A ++M KH K G +IN+SSV + Sbjct: 125 RAAAKLMLKH---KSGRIINISSVVGV 148 >UniRef50_Q56318 Cluster: Uncharacterized oxidoreductase TM_0019; n=11; cellular organisms|Rep: Uncharacterized oxidoreductase TM_0019 - Thermotoga maritima Length = 256 Score = 70.9 bits (166), Expect = 1e-11 Identities = 45/144 (31%), Positives = 75/144 (52%), Gaps = 6/144 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TG GIG ++ ++ + G+K + I +I EEAG + L + G F ++DV Sbjct: 5 KVAVVTGGGQGIGAAIAQLFAENGMK-VVIAEIDEEAGVEREEMLRER-GLDVTFVKTDV 62 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 367 DE ++ V+ GG+DV++NNAA+M+ + +++ I VN+T + Sbjct: 63 ADENSVKNMVRKTVEIYGGVDVLVNNAAVMSVKSIFERPLEEWERVIRVNLTGPYICSRY 122 Query: 368 AIEIMGKHSGGKGGTVINVSSVAA 439 E M K GG +IN++S A Sbjct: 123 CAEEMIKRG---GGVIINIASTRA 143 >UniRef50_Q5HKD7 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Staphylococcus epidermidis|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Staphylococcus epidermidis (strain ATCC 35984 / RP62A) Length = 255 Score = 70.5 bits (165), Expect = 2e-11 Identities = 45/144 (31%), Positives = 81/144 (56%), Gaps = 5/144 (3%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV + G ATGIG+++ L G +I I D+ G+ ++++ G KT + D+ Sbjct: 13 KVAMVIGGATGIGKAMAEALAQAGA-NIVIADLQSNIGQETATTISTQSGVKTTSLKLDI 71 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNA--ALMNDSIGI-YKKAI-EVNVTALITSTLKAI 373 T + I++ VV+E G ID+++NNA ++ +D+ I Y++ + E+N++ + Sbjct: 72 THSDEVNQIVDYVVREYGKIDILVNNASISIQDDTENISYEEWLKEINLS--LNGAFSVA 129 Query: 374 EIMGKHSGGKG-GTVINVSSVAAL 442 + +G+ KG G++INVSSV L Sbjct: 130 QTVGRQMIEKGSGSIINVSSVLGL 153 >UniRef50_Q0SI88 Cluster: Short chain dehydrogenase; n=2; Actinomycetales|Rep: Short chain dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 267 Score = 70.5 bits (165), Expect = 2e-11 Identities = 44/141 (31%), Positives = 74/141 (52%), Gaps = 7/141 (4%) Frame = +2 Query: 38 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTDEE 217 +TG A G+G + L D G + I D+ EE G++ + K G T F + DVTD+ Sbjct: 13 VTGGAKGLGAGMAAALADAGAA-VVIGDVLEEEGRATADSVG-KTGVDTGFVKLDVTDDG 70 Query: 218 HFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLKAIEI 379 ++ + A V++ GG+D+++NNA + S+ + ++ EVN+ + + Sbjct: 71 NWERAVAATVEQLGGLDLLVNNAGIEISSLVVDIDPADIRRMCEVNILGVALGLKHGLRA 130 Query: 380 MGK-HSGGKGGTVINVSSVAA 439 M + G GG ++NVSSVAA Sbjct: 131 MRPGGAAGSGGAIVNVSSVAA 151 >UniRef50_Q03TH6 Cluster: 3-oxoacyl-acyl carrier protein reductase; n=3; Lactobacillales|Rep: 3-oxoacyl-acyl carrier protein reductase - Lactobacillus brevis (strain ATCC 367 / JCM 1170) Length = 249 Score = 70.5 bits (165), Expect = 2e-11 Identities = 47/149 (31%), Positives = 80/149 (53%), Gaps = 8/149 (5%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK-FYR 196 KDKV ITG GIG + + EG K + + + G++ +K+G+ F + Sbjct: 6 KDKVAIITGGVAGIGLGIAECYVREGAKVVVTANHNVDGGRAAV----AKFGDDVSLFVQ 61 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSI-----GIYKKAIEVNVTALIT 355 DV+ E + +++A + + G +D+++NNA + +N +I ++K I+VN+TA Sbjct: 62 QDVSKEADWQKVIDATIAKFGRVDILVNNAGIGGVNTAIEDLDLADWQKVIDVNLTANFL 121 Query: 356 STLKAIEIMGKHSGGKGGTVINVSSVAAL 442 AI+ M K + G++INVSSVA L Sbjct: 122 GEKAAIKAM-KQTADAKGSIINVSSVAGL 149 >UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family; n=16; Bacillaceae|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family - Bacillus anthracis Length = 264 Score = 70.1 bits (164), Expect = 2e-11 Identities = 44/145 (30%), Positives = 77/145 (53%), Gaps = 6/145 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 ++KV+ ITGA++GIGE V + ++G + ++ EE K+L ++ Y +Y Sbjct: 6 QNKVIVITGASSGIGEQVAMQVAEQGATPV-LMARTEEKLKALADKIKETYNTPCYYYVL 64 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITST 361 DV++E + + V+QE G ID+++NNA + S+ K +VNV L+ T Sbjct: 65 DVSEETEVQSVFSKVLQEVGRIDILVNNAGFGIFKTFEDASMDEVKDMFQVNVFGLVACT 124 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVA 436 + M K + G +IN++S+A Sbjct: 125 KAVLPYMVKRNEGH---IINIASLA 146 >UniRef50_Q8F682 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Leptospira interrogans Length = 256 Score = 69.7 bits (163), Expect = 3e-11 Identities = 49/148 (33%), Positives = 78/148 (52%), Gaps = 7/148 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 KDKV +TG +TGIG++VV+ + +GVK + E GK L+ E+ ++ G F Sbjct: 6 KDKVAIVTGGSTGIGKAVVKEFVSKGVK-VVFCGRRLEEGKKLESEIRAE-GGDVYFVVC 63 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSI-----GIYKKAIEVNVTALITS 358 DVT E +++A +++ G +D INNA +M N + ++ K + VN+ S Sbjct: 64 DVTSGEQVKKVVDAALEKFGRLDFGINNAGIMGLNHLLHEYPEDVWDKVVNVNLKGTWLS 123 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVAAL 442 I M K GG V+NVSS++ + Sbjct: 124 MKYQIPEMIKMG---GGVVVNVSSISGI 148 >UniRef50_Q8ELC2 Cluster: Oxidoreductase; n=2; Bacillaceae|Rep: Oxidoreductase - Oceanobacillus iheyensis Length = 244 Score = 69.7 bits (163), Expect = 3e-11 Identities = 43/144 (29%), Positives = 76/144 (52%), Gaps = 6/144 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 +DKV ITG +GIG + ++ EG K I ++D+ EE G S++ EL S+ G++ F ++ Sbjct: 4 QDKVAVITGGVSGIGAATAKLFASEGAKLI-LVDMNEEKGASIEAELKSQ-GSEAIFIKA 61 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 361 DVT+EE I + G +D++ NNA + + ++K +EV++ + Sbjct: 62 DVTNEEQVKNIYTTAIDTFGKVDILFNNAGIGAVKPTEELTYAEWRKTVEVDLDGVFLVA 121 Query: 362 LKAIEIMGKHSGGKGGTVINVSSV 433 AI+ K G ++N +S+ Sbjct: 122 QAAIKEFLK---AGSGVIVNTASM 142 >UniRef50_Q1VR66 Cluster: 3-oxoacyl-[ACP] reductase; n=1; Psychroflexus torquis ATCC 700755|Rep: 3-oxoacyl-[ACP] reductase - Psychroflexus torquis ATCC 700755 Length = 251 Score = 69.7 bits (163), Expect = 3e-11 Identities = 50/143 (34%), Positives = 79/143 (55%), Gaps = 2/143 (1%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K K ITG + GIG+S+ L +EGV +IAI +EA + + EL K G K Sbjct: 6 KGKNAIITGGSKGIGKSIALHLAEEGV-NIAICARGKEALQKTKNELLEK-GVKVFTQTC 63 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGIYKKAIEVNVTALITSTLKAI 373 DV D E F L AV E G +D+++NNA+ M D ++ ++++++ A + +T K + Sbjct: 64 DVGDSEQFNLFLTAVKNEFGSVDILVNNASALTMGDEYQDWEASLQIDLMASVRATKKVV 123 Query: 374 EIMGKHSGGKGGTVINVSSVAAL 442 M + SG G ++ +SSV+ L Sbjct: 124 PWMSE-SG--SGNILFISSVSGL 143 >UniRef50_A5IGZ5 Cluster: Acetyoacetyl CoA reductase; n=4; Legionella pneumophila|Rep: Acetyoacetyl CoA reductase - Legionella pneumophila (strain Corby) Length = 248 Score = 69.7 bits (163), Expect = 3e-11 Identities = 45/146 (30%), Positives = 74/146 (50%), Gaps = 7/146 (4%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE-EAGKSLQVELNSKYGNKTKFYRS 199 + VV ITG IG +V + LD KH+ LD+ + G+ +L ++ F Sbjct: 4 NNVVLITGGTGDIGTAVAK-QLDSTFKHVIALDLVSYDEGEVWLHDLKTQGYKNINFRHM 62 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 361 DVTD E ++ +++E GGIDV+INNA + D++ + + + VN+ + T Sbjct: 63 DVTDYEQCAEVIGLIIEEFGGIDVLINNAGITRDAVFTKMTKRQWDEVLRVNLDGMFNVT 122 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAA 439 + +E M G+ ++NVSSV A Sbjct: 123 KQVVESMKVQESGR---IVNVSSVNA 145 >UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8; Bacteria|Rep: Short-chain alcohol dehydrogenase - Burkholderia dolosa AUO158 Length = 284 Score = 69.7 bits (163), Expect = 3e-11 Identities = 44/146 (30%), Positives = 82/146 (56%), Gaps = 6/146 (4%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 202 +KVV ITGA++GIGE+ ++L +G +A+ + + + E+ +K G + ++ D Sbjct: 44 NKVVVITGASSGIGEATAKLLASKGAT-VALAARRLDKLQRVAAEIVAK-GGQVSVHQVD 101 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS-IGIYK-----KAIEVNVTALITSTL 364 VTD+E ++N VV + G +DV++NNA LM + + + K + I++N+ L+ Sbjct: 102 VTDQEQVNRLINDVVSQHGRLDVMVNNAGLMAIAPLSLRKTDEWDRMIDINIKGLLYGVA 161 Query: 365 KAIEIMGKHSGGKGGTVINVSSVAAL 442 A+ + K + G +N++SV L Sbjct: 162 AALPVFEKQ---QSGHFVNIASVVGL 184 >UniRef50_Q9WYD3 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Thermotoga|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Thermotoga maritima Length = 257 Score = 69.3 bits (162), Expect = 4e-11 Identities = 44/145 (30%), Positives = 71/145 (48%), Gaps = 6/145 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K KV +TG GIG+++ + L G + I+DI EE + E+ K G + FY Sbjct: 11 KRKVALVTGGGQGIGKAIAQALAAAGAA-VLIMDINEETARRTVEEIKEK-GGEADFYVG 68 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 361 DVT EE G + + G +D+ +NNA + N + +KK I+VN+ + S Sbjct: 69 DVTKEEDCFGAVKKALDRWGKLDIGVNNAGIGDWCEAENYPVEKWKKVIDVNLVGVFLSA 128 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVA 436 M + GK +IN++S++ Sbjct: 129 KAEFHAMKERKYGK---IINIASMS 150 >UniRef50_Q5QW23 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase, putative; n=26; Gammaproteobacteria|Rep: 3-oxoacyl-(Acyl carrier protein) reductase, putative - Idiomarina loihiensis Length = 254 Score = 69.3 bits (162), Expect = 4e-11 Identities = 49/154 (31%), Positives = 74/154 (48%), Gaps = 15/154 (9%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 KD V+ ITG A G+G ++ +G K +A++DI + Q + K Y Sbjct: 4 KDSVIVITGGAQGLGLAMAEDFARQGAK-LALIDINGDVLGEAQEQCEKLGAAKVVGYEV 62 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI---------------YKKAIEV 334 D+TDEE + + QE GIDV++NNA L+ D + I ++ ++V Sbjct: 63 DITDEESVETVFEQIQQEFDGIDVLVNNAGLLRDGLLIKFKDGELKQKMPLQQFQSVLDV 122 Query: 335 NVTALITSTLKAIEIMGKHSGGKGGTVINVSSVA 436 N+T +A M K GK G +IN+SSVA Sbjct: 123 NLTGTFLCGREAAAQMVK--AGKKGVIINISSVA 154 >UniRef50_Q3VZL7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 261 Score = 69.3 bits (162), Expect = 4e-11 Identities = 48/151 (31%), Positives = 74/151 (49%), Gaps = 9/151 (5%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 193 E KV ITG G G++ L + G H+ + DI + + EL + G+ T Sbjct: 14 EHAGKVALITGGGRGFGKAFGAALTERGA-HVVLADIDGDVASAAAAELTALGGSATGV- 71 Query: 194 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI---------GIYKKAIEVNVTA 346 DVTDE ++ +V+ GG+D+++NNA L + + G ++ EVNV Sbjct: 72 TCDVTDEARVGEVVADIVRAHGGLDILVNNAGLHSAAFNKPTAELGAGQIRRLFEVNVMG 131 Query: 347 LITSTLKAIEIMGKHSGGKGGTVINVSSVAA 439 ++ TL A + M SG G V+N+SS AA Sbjct: 132 VVICTLAAKDAM---SGRAGAAVVNISSSAA 159 >UniRef50_Q9WYG0 Cluster: Uncharacterized oxidoreductase TM_0325; n=2; Thermotoga|Rep: Uncharacterized oxidoreductase TM_0325 - Thermotoga maritima Length = 251 Score = 69.3 bits (162), Expect = 4e-11 Identities = 51/148 (34%), Positives = 75/148 (50%), Gaps = 6/148 (4%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 196 ++ KVV ITGA +GIG+ + + G K +AI DI+EE GK VEL G + F Sbjct: 3 FQGKVVLITGAGSGIGKKAAVMFAERGAK-VAINDISEEKGKE-TVELIKSMGGEAAFIF 60 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITS 358 DV + I+ V+ G +D+++NNA ++ S + K + VNV Sbjct: 61 GDVAKDAE--QIVKKTVETFGRLDILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFLL 118 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVAAL 442 + A+E M K GG ++NVSS A L Sbjct: 119 SKYAVEQMKKQG---GGVIVNVSSEAGL 143 >UniRef50_A0X2J5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Shewanella pealeana ATCC 700345|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella pealeana ATCC 700345 Length = 254 Score = 68.9 bits (161), Expect = 5e-11 Identities = 45/145 (31%), Positives = 82/145 (56%), Gaps = 6/145 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV ITGAA G+G + R++ EG + + + DI E GK E+ + GN + F DV Sbjct: 8 KVALITGAARGVGLATARLMAREGAQ-VVLTDINAEQGK----EIANSIGNNSLFIEHDV 62 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTLK 367 T E + ++N + + G +++++NNAA++ +++ +++ VN ++ Sbjct: 63 TKEADWSAVINHIEAKFGQLNILLNNAAILQLGDIKEETLAGWQRVHMVNSDSVFLRIHY 122 Query: 368 AIEIMGKHSGGKGGTVINVSSVAAL 442 A+ +M K SG GG++IN+SS +A+ Sbjct: 123 ALPLMEK-SG--GGSIINMSSSSAV 144 >UniRef50_Q8ELN8 Cluster: Glucose 1-dehydrogenase; n=6; cellular organisms|Rep: Glucose 1-dehydrogenase - Oceanobacillus iheyensis Length = 256 Score = 68.5 bits (160), Expect = 7e-11 Identities = 45/146 (30%), Positives = 74/146 (50%), Gaps = 7/146 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 +DKV +TGAA G+G++ IL E + I D EE G+ + VE + G + F + Sbjct: 7 EDKVAIVTGAAMGMGKATA-ILFAESKAKVVIADFNEEKGQEV-VEEVKQAGGQAAFIKV 64 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITS 358 D++D ++ V + G +D+ +NNAAL D + K I V++T T+ Sbjct: 65 DISDSAQVKQMVQFAVDQFGKLDIAVNNAALTPDDKPASEFDEDYWDKLISVDLTG--TA 122 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVA 436 E+ G GG+++N+SSV+ Sbjct: 123 LCMKYELQQLLEQGNGGSIVNISSVS 148 >UniRef50_Q5WBW4 Cluster: Oxidoreductase; n=1; Bacillus clausii KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain KSM-K16) Length = 257 Score = 68.5 bits (160), Expect = 7e-11 Identities = 44/146 (30%), Positives = 84/146 (57%), Gaps = 7/146 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K +TG A G+G ++ + L G IAI+DI EA E+ + Y T+ ++DV Sbjct: 12 KHAVVTGGAQGLGFTIAKSLAAFGCD-IAIVDIDAEAAAKAAQEITTTYSVNTQSIQADV 70 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMN--DSIGI----YKKAIEVNVTALITSTLK 367 + EE +++ V++ IDV++NNA ++ D++ + +K+ ++VN+ AL ++ + Sbjct: 71 SKEEEVSAMVDRVLESFPQIDVLVNNAGIVKKIDTLDMTYSDWKRTMDVNINALFLTSKQ 130 Query: 368 AIEIMGKHSGGKG-GTVINVSSVAAL 442 +GKH G G+++N+SS++A+ Sbjct: 131 ----VGKHMVANGSGSIMNMSSMSAM 152 >UniRef50_Q8YHE0 Cluster: GLUCOSE 1-DEHYDROGENASE II; n=4; Brucellaceae|Rep: GLUCOSE 1-DEHYDROGENASE II - Brucella melitensis Length = 272 Score = 68.1 bits (159), Expect = 9e-11 Identities = 45/145 (31%), Positives = 76/145 (52%), Gaps = 6/145 (4%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 196 +KDKVV +TG A+GIGE+ R + EG K + I D ++ G+ L EL + + F + Sbjct: 3 FKDKVVIVTGGASGIGEATARAFIREGAK-VVIADFSDH-GQQLADELAGAH-EQALFIK 59 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITS 358 +DV D ++ V+ G +D++ NA + D+ ++K I++N+T + Sbjct: 60 TDVADTRAVQALIARTVENYGRLDIMFANAGIAADAPIDELDEAAWQKTIDINLTGVYLC 119 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSV 433 AI+ M S G GG ++N S+ Sbjct: 120 DKYAIDQM--RSQG-GGVIVNCGSI 141 >UniRef50_Q8ETD2 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n=2; Bacillaceae|Rep: 2O-beta-hydroxysteroid dehydrogenase - Oceanobacillus iheyensis Length = 244 Score = 68.1 bits (159), Expect = 9e-11 Identities = 46/152 (30%), Positives = 81/152 (53%), Gaps = 6/152 (3%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 ++KV ITG A G+G S VR+ EG K + D+ EE G +L EL G KF + Sbjct: 5 ENKVAIITGGARGMGASHVRLFAKEGAK-VVFTDLNEEGGLALANEL----GENVKFVKQ 59 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 361 DVT+ + + +++ + G ++V++NNA LM + Y+K I++N ++ Sbjct: 60 DVTNADDWETVISETEEAFGPVNVLVNNAGISLSIPLMEMTEEQYRKIIDINQVSVFLG- 118 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHV 457 +KA+ + +G G+++N+SS+ + V Sbjct: 119 MKAVVPSMQKAG--SGSIVNISSMNGIVAGAV 148 >UniRef50_Q8CUW5 Cluster: 3-oxoacyl-(Acyl carrier protein) reductase; n=9; Firmicutes|Rep: 3-oxoacyl-(Acyl carrier protein) reductase - Oceanobacillus iheyensis Length = 253 Score = 68.1 bits (159), Expect = 9e-11 Identities = 40/152 (26%), Positives = 81/152 (53%), Gaps = 7/152 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 KDKV +TGAA+G+G+++ + EG K + + D+ EE +S+ E+ S G T + Sbjct: 4 KDKVAIVTGAASGMGKAIATLYASEGAK-VIVADLNEEGAQSVVEEITSNNGVATAI-KV 61 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN--DSIG-----IYKKAIEVNVTALITS 358 ++ +E +++ V G +D+++NNA +M+ +++G + ++N ++ + Sbjct: 62 NIAQKEDIDKMIDTAVDTYGTLDILVNNAGIMDGFEAVGDVEDDRWDLIFDINTKGVMRA 121 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVAALTQSH 454 KAI I + + G ++N +S L +H Sbjct: 122 MRKAIPIFLEK---ESGVIVNTASTGGLNGAH 150 >UniRef50_Q7W2M6 Cluster: Alcohol dehydrogenase; n=15; cellular organisms|Rep: Alcohol dehydrogenase - Bordetella parapertussis Length = 252 Score = 67.3 bits (157), Expect = 2e-10 Identities = 41/144 (28%), Positives = 72/144 (50%), Gaps = 5/144 (3%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K +TGA +G GE + EG K + + DI E G+ + +N+ G + F R+DV Sbjct: 6 KTAIVTGAGSGFGEGIAATFAREGAK-VVVADINEAGGQRVAAAINAA-GGQAVFVRADV 63 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 385 +D +L A ++ GG+D+V+NNA + + + + E + +K+I + Sbjct: 64 SDNAAVANLLAATLKAFGGLDIVVNNAGTTHRNRPML-EVEEDEFDRIYAINVKSIYLTA 122 Query: 386 KH-----SGGKGGTVINVSSVAAL 442 +H GG+ IN++S AA+ Sbjct: 123 RHMVPHFRAHGGGSFINIASTAAI 146 >UniRef50_Q9X429 Cluster: CylG; n=8; Streptococcus agalactiae|Rep: CylG - Streptococcus agalactiae Length = 240 Score = 67.3 bits (157), Expect = 2e-10 Identities = 43/146 (29%), Positives = 75/146 (51%), Gaps = 7/146 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TG GIG ++ + L EG K IAI + + ++LQ EL K Y+ ++ Sbjct: 2 KVAIVTGGTRGIGRAITKELYKEGYKVIAIYNSNDAKARALQEEL-----PKLDVYKCNI 56 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 367 +D + ++ + +E GGID ++NNA ++ D + + I +N+ L+ + Sbjct: 57 SDAKAVQKLVTKIFREYGGIDCLVNNAGIVRDGFFLMMSKEKWMDVININIMGLVNMSKA 116 Query: 368 AIEIM-GKHSGGKGGTVINVSSVAAL 442 ++IM K GK VIN+SS + + Sbjct: 117 VLKIMKAKRIQGK---VINISSTSGI 139 >UniRef50_Q1ARM4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 252 Score = 67.3 bits (157), Expect = 2e-10 Identities = 50/145 (34%), Positives = 71/145 (48%), Gaps = 6/145 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV ITG ATGIG + + EG + I DI EE G S VE G F R DV Sbjct: 7 KVALITGGATGIGRATALLFAREGA-CVLIGDINEE-GASETVEAVRAAGGDAAFRRCDV 64 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 367 + EE ++ A +E G +DVV NA L+ S ++ + +N+TA T Sbjct: 65 SGEEEIAALVAAAGEEYGRLDVVFGNAGLLRTRPLEDLSTKEFELHLRINLTANFLLTKY 124 Query: 368 AIEIMGKHSGGKGGTVINVSSVAAL 442 A +M +H +GG++I ++S L Sbjct: 125 AAPVMRRH---EGGSIIFMASAGGL 146 >UniRef50_A5WE64 Cluster: Short-chain dehydrogenase/reductase SDR; n=6; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1 Length = 260 Score = 67.3 bits (157), Expect = 2e-10 Identities = 47/153 (30%), Positives = 78/153 (50%), Gaps = 7/153 (4%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 202 +K + ITG A+GIG + ++L G K I I D+AE+ G +L + + + F + D Sbjct: 14 NKRILITGGASGIGAASAKLLASRGAK-IIIADLAEDLGHALAQQAWAS-DHTINFMKVD 71 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-------KAIEVNVTALITST 361 VT + V++ GG+DVVINNA + + +++ + + VNV + Sbjct: 72 VTQAAEVNALFAYAVEQLGGLDVVINNAGVDHPPAPLHQLTEDDFDRCMTVNVKGVWHCM 131 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAALTQSHVM 460 AI + H GG VINV+S+A L + ++ Sbjct: 132 RAAIACLSPHGGGH---VINVASIAGLRSAPML 161 >UniRef50_A3I824 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Bacillus sp. B14905 Length = 254 Score = 67.3 bits (157), Expect = 2e-10 Identities = 42/148 (28%), Positives = 74/148 (50%), Gaps = 6/148 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 ++KV ITG TGIG+ + EG K I I DI E++G ++ + +G + F Sbjct: 7 ENKVAVITGGGTGIGKETALLFAKEGAK-IVITDINEQSGNETVSDIQA-FGGEALFVLH 64 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 361 DV++E+ + + + + +D++ NNA L + + + + +NVT + Sbjct: 65 DVSNEDDWKKVADEAIHTFNKVDILFNNAGIYIIKPLAEIELSDWNRLMSINVTGVFLGM 124 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAALT 445 + +M K + G+VIN SS+A LT Sbjct: 125 KHIMPLMAKQN---KGSVINASSIAGLT 149 >UniRef50_A6EZZ8 Cluster: Short chain dehydrogenase; n=1; Marinobacter algicola DG893|Rep: Short chain dehydrogenase - Marinobacter algicola DG893 Length = 252 Score = 66.9 bits (156), Expect = 2e-10 Identities = 49/144 (34%), Positives = 76/144 (52%), Gaps = 7/144 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TGA IGE V R+L EG IA++D+ + + ++ + G + K + DV Sbjct: 6 KVAIVTGAGRNIGEEVSRVLSAEGAT-IAVVDLDRSRAEKVAADIVAS-GGQAKPFICDV 63 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-KAIEVNVTALITSTLK----- 367 E+ + AVV + GG+D+++NN A M+D+ I+ A E N T IT T Sbjct: 64 ASEDQIRATVAAVVDQLGGLDILVNNVA-MSDNKHIFDITAEEWNRTLAITLTAPFLFGK 122 Query: 368 -AIEIMGKHSGGKGGTVINVSSVA 436 A + M +H+ G +INVSS + Sbjct: 123 YAAQAMVQHAA--DGRIINVSSTS 144 >UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3; Bacillus|Rep: Cyclohexanol dehydrogenase - Bacillus sp. SG-1 Length = 279 Score = 66.9 bits (156), Expect = 2e-10 Identities = 43/148 (29%), Positives = 75/148 (50%), Gaps = 7/148 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 ++K ITGA +G+G+S L EG+ IA++DI EE G VE+ + G F ++ Sbjct: 31 ENKAAIITGAGSGLGQSAAVRLAKEGI-DIAVVDINEEGGNE-TVEMVKQKGVNAIFIKA 88 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNVTALITS 358 DV+ E ++ V+E G +D NNA + +N I ++ + +N+ + Sbjct: 89 DVSKAEEVKNYVDKTVEEFGKVDYFFNNAGISGSGQYFLNTEIEEIEQVVSINLMGALYG 148 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVAAL 442 E+M K+ GG+++N +S A + Sbjct: 149 VRYVAEVMMKNG---GGSIVNTASSAGV 173 >UniRef50_A1B0V7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=6; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Paracoccus denitrificans (strain Pd 1222) Length = 253 Score = 66.9 bits (156), Expect = 2e-10 Identities = 42/150 (28%), Positives = 76/150 (50%), Gaps = 6/150 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 KDKVV ITGA GIG + ++ ++EG + + + D +A + + EL G + + Sbjct: 6 KDKVVLITGAGAGIGAATAKLFIEEGAR-VVVADYLGDAAEQVAAEL----GENARAFTV 60 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITST 361 DV+ E +++ V E GG+DV++NNA + ++ I+VN+T + + Sbjct: 61 DVSKAEACKAMVDFTVAEFGGLDVLVNNAGRGSLGTVETQDENDWRSIIDVNLTGVYLCS 120 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAALTQS 451 A+ + K GG ++N +S A+ + Sbjct: 121 KYAVPELRKRG---GGAIVNTASNIAMAMA 147 >UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Short-chain dehydrogenase/reductase SDR - Candidatus Nitrosopumilus maritimus SCM1 Length = 253 Score = 66.9 bits (156), Expect = 2e-10 Identities = 42/146 (28%), Positives = 80/146 (54%), Gaps = 7/146 (4%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 202 DKV +TGA++ IG+ + + ++EG K I I E ++ + E+ ++ + T D Sbjct: 5 DKVAIVTGASSDIGKGIAKKFVEEGAKVILIARNLEGL-ENTRKEIGNE--DSTAAMTCD 61 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALITST 361 + DE L ++N ++ G ID+++NNA +ND I + +K I VN+ + T Sbjct: 62 LVDESQTLQVVNQIMDTYGKIDILVNNAGAINDPIHFHEMQNSEIQKLINVNLLGVFNMT 121 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAA 439 KA ++ K + K G+++N+ S+++ Sbjct: 122 -KA--VLTKMADVKSGSIVNIGSISS 144 >UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20; Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase - Oceanobacillus iheyensis Length = 255 Score = 66.5 bits (155), Expect = 3e-10 Identities = 50/147 (34%), Positives = 78/147 (53%), Gaps = 13/147 (8%) Frame = +2 Query: 38 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTDEE 217 +TG A+G+GE+ VR L ++G K +AI D+ +E G+ L EL G+ +++ DVTDE Sbjct: 10 VTGGASGLGEATVRRLHNQGGK-VAIFDLNKENGERLATEL----GDNVDYFQVDVTDET 64 Query: 218 HFLGILNAVVQEQGGIDVVINNA--ALMNDSIG--------IYKKAIEVNVTALITSTLK 367 L+ V+++ GI V+N A A+ +IG + IE+N+ Sbjct: 65 SVQKALDNVMEQSDGIHAVVNCAGIAIAEKTIGKKGVHSLQHFSNVIEINLIGTFNVIRL 124 Query: 368 AIEIMGKHS---GGKGGTVINVSSVAA 439 A E M +S G+ G +IN +SVAA Sbjct: 125 AAEKMALNSPNDEGERGVIINTASVAA 151 >UniRef50_Q8ELC1 Cluster: Oxidoreductase; n=1; Oceanobacillus iheyensis|Rep: Oxidoreductase - Oceanobacillus iheyensis Length = 257 Score = 66.5 bits (155), Expect = 3e-10 Identities = 46/156 (29%), Positives = 83/156 (53%), Gaps = 7/156 (4%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 193 +++DKV+ +TGAA GIG+ VVR + + K + ++D+ E+A KS+Q EL N + Sbjct: 3 KFQDKVIIVTGAAGGIGKEVVRKVANAQAK-VVLVDLNEDAIKSVQAELGLTEEN-SFVV 60 Query: 194 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALI 352 ++DV++EE+ ++ + + G ID +NNA + + I + +NV ++ Sbjct: 61 KADVSNEENVKNYVDQTIAKFGRIDGFVNNAGVEGPAKSIEEITEKEFDFVYGINVKGVL 120 Query: 353 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVM 460 + +M K G+++N +SVA L S M Sbjct: 121 FGLKYVLPVM---KAQKSGSIVNTASVAGLIGSPSM 153 >UniRef50_Q3IE74 Cluster: 2O-beta-hydroxysteroid dehydrogenase; n=2; Proteobacteria|Rep: 2O-beta-hydroxysteroid dehydrogenase - Pseudoalteromonas haloplanktis (strain TAC 125) Length = 262 Score = 66.5 bits (155), Expect = 3e-10 Identities = 43/146 (29%), Positives = 76/146 (52%), Gaps = 6/146 (4%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 202 +KV +TGAA GIG ++ + L+D G IA + EE + Q + G+K D Sbjct: 9 NKVALVTGAARGIGRAICQALVDSGATVIATDILTEELNQMAQ-----ELGDKVTPMTHD 63 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 364 VTDE + I++A +++ ID+++NNA ++ ++K I++N+T Sbjct: 64 VTDELQWQSIVSATLEKHQKIDILVNNAGILLFATLETTEPQQFRKLIDINITGTFLGLH 123 Query: 365 KAIEIMGKHSGGKGGTVINVSSVAAL 442 I M K +G G ++N+SS +++ Sbjct: 124 SVIPCM-KKAG--SGAIVNISSASSI 146 >UniRef50_Q7SI45 Cluster: Putative uncharacterized protein NCU00606.1; n=2; Sordariales|Rep: Putative uncharacterized protein NCU00606.1 - Neurospora crassa Length = 262 Score = 66.5 bits (155), Expect = 3e-10 Identities = 40/145 (27%), Positives = 78/145 (53%), Gaps = 7/145 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K V TGAA G+G+ + L G ++ I D+ ++ +++ E Y ++ ++DV Sbjct: 7 KTVLATGAAGGLGKVIAETFLAAGA-NVIICDVNQQRNSAVEEEWTRTYADRFLIKQTDV 65 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMND-------SIGIYKKAIEVNVTALITSTL 364 ++E +++A V + G +DV++NNAA+M+D S ++ + + +N+T +T Sbjct: 66 SNEAAVQELIDASVAKFGRLDVLVNNAAIMDDFSPAGDCSKELWDRVMAINLTGPFLTTK 125 Query: 365 KAIEIMGKHSGGKGGTVINVSSVAA 439 A++ K GG +IN+ S A+ Sbjct: 126 AAVKQFEKQKQA-GGIIINIGSNAS 149 >UniRef50_P19992 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; n=3; Actinomycetales|Rep: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase - Streptomyces exfoliatus (Streptomyces hydrogenans) Length = 255 Score = 66.5 bits (155), Expect = 3e-10 Identities = 43/145 (29%), Positives = 75/145 (51%), Gaps = 6/145 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K V ITG A G+G R + G + + + D+ +E G + EL G+ ++ DV Sbjct: 7 KTVIITGGARGLGAEAARQAVAAGAR-VVLADVLDEEGAATAREL----GDAARYQHLDV 61 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLK 367 T EE + ++ +E G +D ++NNA L +S+ ++K +++N+T + Sbjct: 62 TIEEDWQRVVAYAREEFGSVDGLVNNAGISTGMFLETESVERFRKVVDINLTGVFIGMKT 121 Query: 368 AIEIMGKHSGGKGGTVINVSSVAAL 442 I M K +G GG+++N+SS A L Sbjct: 122 VIPAM-KDAG--GGSIVNISSAAGL 143 >UniRef50_Q8CNF1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=2; Staphylococcus epidermidis|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Staphylococcus epidermidis (strain ATCC 12228) Length = 263 Score = 66.1 bits (154), Expect = 3e-10 Identities = 45/147 (30%), Positives = 75/147 (51%), Gaps = 7/147 (4%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELN-SKYGNKTKF 190 E ++KVV ITGAAT IG+S+ K + + +++ +K+G +T Sbjct: 4 ELENKVVLITGAATEIGKSIAENFGKAKAKVVINYRSDRHHDEIEEIKQTVAKFGGQTLV 63 Query: 191 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALI 352 + DV+ EE ++ + G +D++INNA N SI ++K I++N+T Sbjct: 64 VQGDVSIEEDIKRMIETTINHFGTLDIIINNAGFENSIPTHEMSIDDWQKVIDINLTGAF 123 Query: 353 TSTLKAIEIMGKHSGGKGGTVINVSSV 433 + +AI K + K GT+IN+SSV Sbjct: 124 VGSREAINQFLKEN--KKGTIINISSV 148 >UniRef50_Q47PW1 Cluster: Short-chain dehydrogenase/reductase (SDR) family protein; n=1; Thermobifida fusca YX|Rep: Short-chain dehydrogenase/reductase (SDR) family protein - Thermobifida fusca (strain YX) Length = 282 Score = 66.1 bits (154), Expect = 3e-10 Identities = 45/146 (30%), Positives = 74/146 (50%), Gaps = 5/146 (3%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 + +V ITG A+GIGE+ VR EG + I DI EAG+ L EL G++ F R+ Sbjct: 6 RGRVAAITGGASGIGEATVRRFHTEGAS-VVIADIQAEAGRRLADEL----GDRAVFVRT 60 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 379 DV++E +++ V G +D+++NNA +M ++G + I L+ + Sbjct: 61 DVSEEADVAALVDTAVDRFGQLDIMVNNAGIMG-ALGPIDATRMSDADLTIAVNLRGVIC 119 Query: 380 MGKHSG-----GKGGTVINVSSVAAL 442 KH+ + G +I+ SS A + Sbjct: 120 GMKHAARVMKPRRSGVIISTSSPAGV 145 >UniRef50_Q46SG2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=1; Ralstonia eutropha JMP134|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 258 Score = 66.1 bits (154), Expect = 3e-10 Identities = 44/145 (30%), Positives = 76/145 (52%), Gaps = 6/145 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K+ +TG A+G+G + R L EG + + DI AG + + EL G F R DV Sbjct: 6 KIALVTGGASGMGLAFTRRLAQEGAR-VYFTDINGAAGHATESELQGA-GLAVVFLRHDV 63 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIGI-----YKKAIEVNVTALITSTLK 367 T E +L +L + G +DV++NNA + ++ +I + + + VN+ ++ Sbjct: 64 TQENDWLRVLEHIGAVDGRLDVLVNNAGIAISHNIETCTTEDFDRTLNVNLKSVFLGCKH 123 Query: 368 AIEIMGKHSGGKGGTVINVSSVAAL 442 + +M + KGG++INVSS+ A+ Sbjct: 124 GLALMKQ----KGGSIINVSSITAI 144 >UniRef50_A6SWD9 Cluster: Short chain dehydrogenase; n=5; Proteobacteria|Rep: Short chain dehydrogenase - Janthinobacterium sp. (strain Marseille) (Minibacterium massiliensis) Length = 278 Score = 66.1 bits (154), Expect = 3e-10 Identities = 49/150 (32%), Positives = 71/150 (47%), Gaps = 7/150 (4%) Frame = +2 Query: 8 SHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK 187 S+E V ITGA TGIG + EG + +A+ EEAG +L EL + GN+ + Sbjct: 27 SNEMNTPTVLITGALTGIGRATAFAFAREGYR-VAVSGRREEAGNALAAELRA-LGNEAE 84 Query: 188 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTA 346 F +DV E ++ V G IDV +NNA ++ S Y + VNV Sbjct: 85 FLLADVRFEADVRNLVEQTVVRFGRIDVAVNNAGTEGQLAPIVEQSAANYAETFGVNVLG 144 Query: 347 LITSTLKAIEIMGKHSGGKGGTVINVSSVA 436 + S + +M G++IN+SSVA Sbjct: 145 TMLSLKHEMRVMLAQG---SGSIINLSSVA 171 >UniRef50_A4XF64 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Novosphingobium aromaticivorans (strain DSM 12444) Length = 266 Score = 66.1 bits (154), Expect = 3e-10 Identities = 45/141 (31%), Positives = 73/141 (51%), Gaps = 4/141 (2%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 202 ++ +TGAA GIGE + R EG + + D +E G ++ +L G + +F R D Sbjct: 8 NRAAVVTGAADGIGEGIARRFAAEGAA-VVVADYDDERGPAVARDLRG-LGARAEFIRCD 65 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTAL---ITSTLKAI 373 V+ E +G ++ V+ G +D+++NNA + I KK E AL + +T A+ Sbjct: 66 VSRREDVIGAVDLCVERFGSVDILVNNAYRGEGPVRIEKKTDERFDEALRMCLFATKWAM 125 Query: 374 EIMGKHSGGKG-GTVINVSSV 433 E H KG G VIN++S+ Sbjct: 126 ERALPHMKAKGWGRVINMASL 146 >UniRef50_Q9I7R3 Cluster: CG18814-PA; n=3; Sophophora|Rep: CG18814-PA - Drosophila melanogaster (Fruit fly) Length = 285 Score = 66.1 bits (154), Expect = 3e-10 Identities = 49/162 (30%), Positives = 81/162 (50%), Gaps = 17/162 (10%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS-D 202 K V G GIG+ V+ LL + +K +AI D+ + L E ++ + FY+ D Sbjct: 6 KNVVYLGGFGGIGKKCVQELLKKQIKGLAIFDLIVD--DDLLAEWKKQHPDTEIFYQKMD 63 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMND-----SIGIYKKAIEVNVT-------- 343 +T + A ++ G DVV+N + L++D +I I +E+ ++ Sbjct: 64 ITQKSDIDAAYKATAEKLGHFDVVVNGSGLLDDRRIELTIQINLVILEIVLSKGFIYQYF 123 Query: 344 ---ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVM 460 +I STL A+E M K GG+GG ++N+SSVA L + +M Sbjct: 124 LKVGVINSTLTALEYMDKSKGGRGGLIVNISSVAGLQPTPLM 165 >UniRef50_Q54D03 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 292 Score = 66.1 bits (154), Expect = 3e-10 Identities = 42/142 (29%), Positives = 74/142 (52%), Gaps = 6/142 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV F+TG A+GIG +V + EG K +AI+D+ + + ELN ++ T DV Sbjct: 36 KVCFVTGGASGIGLGIVERFVKEGGK-VAIVDLDKTKADNASKELNQRFPGSTISVECDV 94 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 367 ++EE + V+ GG+DV+++NA L + + ++K + V++ T Sbjct: 95 SNEEQVSKGIKDTVERFGGLDVIVSNAGLQHIETLETVELATWRKMMAVHLDGAFLCTKY 154 Query: 368 AIEIMGKHSGGKGGTVINVSSV 433 A++ K +GGT++ + SV Sbjct: 155 AMQEF-KKDIKRGGTILYMGSV 175 >UniRef50_Q88LI6 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=2; Bacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Pseudomonas putida (strain KT2440) Length = 262 Score = 65.7 bits (153), Expect = 5e-10 Identities = 42/152 (27%), Positives = 75/152 (49%), Gaps = 7/152 (4%) Frame = +2 Query: 8 SHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK 187 ++++ KVV +TGA +GIG + G +A+ DI+ + G VEL G + Sbjct: 4 NYDFSGKVVLVTGAGSGIGRATALAFAQSGAS-VAVADISTDHGLKT-VELVKAEGGEAT 61 Query: 188 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTA 346 F+ DV E +L VV GG+D+ NNA + + + + +++ I+VN+++ Sbjct: 62 FFHVDVGSEPSVQSMLAGVVAHYGGLDIAHNNAGIEANIVPLAELDSDNWRRVIDVNLSS 121 Query: 347 LITSTLKAIEIMGKHSGGKGGTVINVSSVAAL 442 + I +M K GG ++N +S + L Sbjct: 122 VFYCLKGEIPLMLKRG---GGAIVNTASASGL 150 >UniRef50_Q7W386 Cluster: Short chain dehydrogenase; n=111; cellular organisms|Rep: Short chain dehydrogenase - Bordetella parapertussis Length = 254 Score = 65.7 bits (153), Expect = 5e-10 Identities = 44/154 (28%), Positives = 76/154 (49%), Gaps = 11/154 (7%) Frame = +2 Query: 11 HEWKDKVVFITGAATGIGESVVRILLDEG----VKHIAILDIAEEAGKSLQVELNSKYGN 178 H +KV+ +TGAA GIG +V + G V + + D AE+ ++++ E G Sbjct: 4 HLSPNKVMIVTGAARGIGAAVALLAARRGYAVCVNYRSRGDAAEQVVQAIRDE-----GG 58 Query: 179 KTKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYK-------KAIEVN 337 + +DV DE + + V +E G +D ++NNA ++ + + + + + N Sbjct: 59 RALAVAADVADEAQVVRMFETVDRELGRVDALVNNAGILEAQMRVEEMDAARITRILATN 118 Query: 338 VTALITSTLKAIEIMGKHSGGKGGTVINVSSVAA 439 V +A+ M GG+GG ++NVSSVAA Sbjct: 119 VVGAFVCCREAVRRMAPRHGGRGGAIVNVSSVAA 152 >UniRef50_Q396N3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 262 Score = 65.7 bits (153), Expect = 5e-10 Identities = 42/145 (28%), Positives = 73/145 (50%), Gaps = 7/145 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 + KV ITG A GIG R L G +AILD+ + ++L E+ ++ G + F+ Sbjct: 11 RGKVAAITGGARGIGAETARTLAAAGAS-VAILDVLSQPAEALVEEIRAQ-GGQAAFWSL 68 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITS 358 DVT E + +V G +DV++NNA + ++ +++ ++VNV + Sbjct: 69 DVTHEADVARVFGEIVAHFGRLDVLVNNAGIEGHNVPTHELTLAQWQRVLDVNVNGVFLC 128 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSV 433 T AI + GG+++N+SS+ Sbjct: 129 TRAAIPHI---DAAGGGSIVNLSSM 150 >UniRef50_Q396I3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Burkholderiaceae|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 252 Score = 65.7 bits (153), Expect = 5e-10 Identities = 43/146 (29%), Positives = 76/146 (52%), Gaps = 6/146 (4%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 202 +KV +TGAA+G+G + +L EG + + + DI E+AG++L E+ G+ F R D Sbjct: 6 NKVALVTGAASGVGRADALLLAAEGAR-VVLTDIDEDAGRALAREI----GDAALFVRHD 60 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 364 + DE + + + + G +DV++NNAA+ + S+ +++ + N Sbjct: 61 IADEAGWQHAIASTLDRFGRLDVLVNNAAICPVGSIEDTSLDTWRRVMRTNADGYFLGCK 120 Query: 365 KAIEIMGKHSGGKGGTVINVSSVAAL 442 AI M G+++ +SSVAAL Sbjct: 121 YAIGAM--KGNDTPGSIVMMSSVAAL 144 >UniRef50_Q83ZE7 Cluster: Short-chain dehydrogenase/redutase; n=1; Terrabacter sp. DBF63|Rep: Short-chain dehydrogenase/redutase - Terrabacter sp. DBF63 Length = 252 Score = 65.7 bits (153), Expect = 5e-10 Identities = 46/148 (31%), Positives = 76/148 (51%), Gaps = 7/148 (4%) Frame = +2 Query: 8 SHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK 187 S+ KV +TG GIG ++L+D G + + + D++E+AG ++ G+ Sbjct: 2 SNSLDGKVALVTGGGGGIGRETAKVLVDHGAR-VVVADLSEDAGNGTLEYIDG--GDAVA 58 Query: 188 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTA 346 F R+DVTD ++ A V G +D+ NNA L + ++ + K I VN+T Sbjct: 59 FVRADVTDLASMQHLVQAAVDRYGRLDIAHNNAGIEVTGPDLADVTVEQFDKVIAVNLTG 118 Query: 347 LITSTLKAIEIMGKHSGGKGGTVINVSS 430 + S +KA EI + G GG++IN +S Sbjct: 119 VFIS-MKA-EIPQMLAQG-GGSIINTAS 143 >UniRef50_A3YCX4 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=1; Marinomonas sp. MED121|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Marinomonas sp. MED121 Length = 259 Score = 65.7 bits (153), Expect = 5e-10 Identities = 47/139 (33%), Positives = 73/139 (52%), Gaps = 6/139 (4%) Frame = +2 Query: 32 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 211 V +TG A+GIGE++V+ L +G ++ DI EEAG+ L LNS +G K F D+TD Sbjct: 20 VLVTGGASGIGEALVKALAQQGCA-VSFFDIDEEAGEQLAQNLNS-HGMKAHFELVDLTD 77 Query: 212 EEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLKAI 373 E + A ++ G I ++NNAA L S + + + VN+ + K Sbjct: 78 IEMLKDKIQARLEAWGAIRALVNNAANDHRHTLAELSSDEFDQCMAVNLKHHFFAAQKVA 137 Query: 374 EIMGKHSGGKGGTVINVSS 430 +M + GG++IN+SS Sbjct: 138 PLMAE---AGGGSIINMSS 153 >UniRef50_Q71R50 Cluster: Dehydrogenase/reductase SDR family member 11 precursor; n=7; Eukaryota|Rep: Dehydrogenase/reductase SDR family member 11 precursor - Gallus gallus (Chicken) Length = 255 Score = 65.7 bits (153), Expect = 5e-10 Identities = 42/145 (28%), Positives = 73/145 (50%), Gaps = 6/145 (4%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 196 W +V +TGA+ GIG +V R L+ G+K + ++ K ++ Y Y+ Sbjct: 4 WTGRVALVTGASVGIGAAVARALVQHGMKVVGCARSVDKIEKLAAECQSAGYPGTLIPYK 63 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITS 358 D+++EE L + +A+ G+DV INNA L++ ++ I+VNV A+ Sbjct: 64 CDLSNEEEILSMFSAIKTLHQGVDVCINNAGLARPEPLLSGKTEGWRTMIDVNVMAVSIC 123 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSV 433 T +A + M K G +IN++S+ Sbjct: 124 TREAYQSM-KERNIDDGHIININSM 147 >UniRef50_UPI0000DB6B86 Cluster: PREDICTED: similar to CG9360-PA; n=2; Apis mellifera|Rep: PREDICTED: similar to CG9360-PA - Apis mellifera Length = 262 Score = 65.3 bits (152), Expect = 6e-10 Identities = 47/150 (31%), Positives = 75/150 (50%), Gaps = 8/150 (5%) Frame = +2 Query: 11 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF 190 H W+ KV +TGA+ GIG ++ R L +K + + E+ K L EL + KF Sbjct: 2 HRWRGKVAIVTGASAGIGAAIARALPSHDIKVVGLARNIEKLEK-LADEL-----GRDKF 55 Query: 191 Y--RSDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTA 346 + + DVT EE L V E GG D++INNA AL++ Y+ ++ N+ A Sbjct: 56 FPIKCDVTKEEDILKACKWVENELGGADILINNAGIIRFNALIDQKTEDYRSVLDTNLLA 115 Query: 347 LITSTLKAIEIMGKHSGGKGGTVINVSSVA 436 + + I + K + G +IN+SS++ Sbjct: 116 PAIFSREIISSIKKRNA--QGHIINISSIS 143 >UniRef50_Q0LSE4 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caulobacter sp. K31|Rep: Short-chain dehydrogenase/reductase SDR - Caulobacter sp. K31 Length = 277 Score = 65.3 bits (152), Expect = 6e-10 Identities = 44/145 (30%), Positives = 75/145 (51%), Gaps = 6/145 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K+ +TGAA G+G ++ + L+EG + + D++EE EL + + R DV Sbjct: 9 KIAIVTGAARGLGAAIAKRYLEEGAT-VVLADLSEEKTTERAAELGAGAHGR----RCDV 63 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 367 D E F +++A V E G +D+++NNA + S+ + + VNV+++ Sbjct: 64 GDWEAFSTLIDATVAEFGRLDILVNNAGINRAGLVPGFSLQHWDDLLRVNVSSVFYGCRA 123 Query: 368 AIEIMGKHSGGKGGTVINVSSVAAL 442 AI M + GG +INV+S+A L Sbjct: 124 AIPHMRRQG---GGAIINVASIAGL 145 >UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Enterobacter sp. 638|Rep: Short-chain dehydrogenase/reductase SDR precursor - Enterobacter sp. 638 Length = 242 Score = 65.3 bits (152), Expect = 6e-10 Identities = 45/147 (30%), Positives = 77/147 (52%), Gaps = 6/147 (4%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 193 E K +V +TGA++GIGE++ R L G++ + + E + V L S+ G+ Sbjct: 4 EKKKRVAVVTGASSGIGEALARELAGNGIQVVLLARRFER----IDV-LASELGHGAIAI 58 Query: 194 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALIT 355 ++DVTD E + N V Q GG+D++INNA +M + + +++ +E N+ +T Sbjct: 59 KADVTDRESIVAAANQVEQTLGGVDILINNAGVMLTGPFDSSQLDEHRQMVETNLLGAMT 118 Query: 356 STLKAIEIMGKHSGGKGGTVINVSSVA 436 T E+ G ++N+SSVA Sbjct: 119 VT----EVFLPQLRRNKGDLVNISSVA 141 >UniRef50_A1ULZ8 Cluster: Short-chain dehydrogenase/reductase SDR; n=18; Corynebacterineae|Rep: Short-chain dehydrogenase/reductase SDR - Mycobacterium sp. (strain KMS) Length = 253 Score = 65.3 bits (152), Expect = 6e-10 Identities = 48/156 (30%), Positives = 72/156 (46%), Gaps = 9/156 (5%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 193 E+KDKV +TGA GIG++ L EG + + DI + + + + + GN Sbjct: 7 EFKDKVAIVTGAGGGIGQAYAEALAREGAA-VVVADINVDGAQKVADGIKGEGGNALA-V 64 Query: 194 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA---------LMNDSIGIYKKAIEVNVTA 346 R DV+D + + + E GGID ++NNAA L+ YKK + VN+ Sbjct: 65 RVDVSDPDSAKEMAAQTLSEFGGIDYLVNNAAIFGGMKLDFLITVDWDYYKKFMSVNLDG 124 Query: 347 LITSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSH 454 + T M K GG ++N SS AA S+ Sbjct: 125 ALVCTRAVYRKMAKRG---GGAIVNQSSTAAWLYSN 157 >UniRef50_A0L0X0 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=4; Shewanella|Rep: Short-chain dehydrogenase/reductase SDR precursor - Shewanella sp. (strain ANA-3) Length = 292 Score = 65.3 bits (152), Expect = 6e-10 Identities = 43/151 (28%), Positives = 77/151 (50%), Gaps = 7/151 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEA-GKSLQVELNSKYGNKTKFYR 196 K KV ITG+ +GIG + +L ++G H+ + + EA G+ L E +Y T F Sbjct: 35 KGKVGLITGSTSGIGLATAHVLAEQGC-HLILHGLMPEAEGRRLAAEFAEQYHIHTYFSN 93 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITS 358 +D+ D E ++A V+ G ID+++NNA + + I + I +N+++ + Sbjct: 94 ADLRDPESIHAFMDAGVKALGSIDILVNNAGIQHTENVAHFPIDKWNDIIAINLSSAFHT 153 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVAALTQS 451 +A+ M + + G +IN++SV L S Sbjct: 154 IQQAVPAMAEK---RWGRIINIASVHGLVAS 181 >UniRef50_A0J9Z3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Shewanella woodyi ATCC 51908|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella woodyi ATCC 51908 Length = 255 Score = 65.3 bits (152), Expect = 6e-10 Identities = 41/139 (29%), Positives = 77/139 (55%), Gaps = 6/139 (4%) Frame = +2 Query: 32 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 211 VFITG A+GIG ++VR +++G ++ +D +AG++L L+ G + F+ DVTD Sbjct: 15 VFITGGASGIGAALVRAFVEQGA-NVTFVDTNRDAGEALLQGLDINRGQQVAFHLLDVTD 73 Query: 212 EEHFLGILNAVVQEQGGIDVVINNAA--LMNDSIGI----YKKAIEVNVTALITSTLKAI 373 + ++ Q+ G +D++INN +D+ G+ +K+ + +N+ + ++ A Sbjct: 74 TKQLQQMITEQDQKLGQLDILINNVGNDSRHDADGVDEHEWKQCMAINLDSAFFASQAAY 133 Query: 374 EIMGKHSGGKGGTVINVSS 430 +M + K G +IN SS Sbjct: 134 LVMKQR---KQGVIINFSS 149 >UniRef50_P69166 Cluster: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; n=28; Bacteria|Rep: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase - Mycobacterium bovis Length = 260 Score = 65.3 bits (152), Expect = 6e-10 Identities = 42/145 (28%), Positives = 78/145 (53%), Gaps = 6/145 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV ++G A G+G S VR ++ EG K + DI +E GK++ EL + ++ DV Sbjct: 8 KVALVSGGARGMGASHVRAMVAEGAK-VVFGDILDEEGKAVAAEL----ADAARYVHLDV 62 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 367 T + ++ V GG+ V++NNA ++N ++ +++ ++VN+T + Sbjct: 63 TQPAQWTAAVDTAVTAFGGLHVLVNNAGILNIGTIEDYALTEWQRILDVNLTGVFLGIRA 122 Query: 368 AIEIMGKHSGGKGGTVINVSSVAAL 442 ++ M K +G G++IN+SS+ L Sbjct: 123 VVKPM-KEAG--RGSIINISSIEGL 144 >UniRef50_P39640 Cluster: Bacilysin biosynthesis oxidoreductase bacC; n=5; Bacillus|Rep: Bacilysin biosynthesis oxidoreductase bacC - Bacillus subtilis Length = 253 Score = 65.3 bits (152), Expect = 6e-10 Identities = 45/146 (30%), Positives = 78/146 (53%), Gaps = 6/146 (4%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 202 DK V ITG A+GIG + V+ L + ++ + DI E G+++ + N+ ++ F ++D Sbjct: 5 DKTVLITGGASGIGYAAVQAFLGQQA-NVVVADIDEAQGEAMVRKENN---DRLHFVQTD 60 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTL 364 +TDE + + V GG+DV+INNA + + + K ++VN+T + + Sbjct: 61 ITDEAACQHAVESAVHTFGGLDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSK 120 Query: 365 KAIEIMGKHSGGKGGTVINVSSVAAL 442 A++ M + GK G +IN SV L Sbjct: 121 HALKHM--LAAGK-GNIINTCSVGGL 143 >UniRef50_UPI00015B4F48 Cluster: PREDICTED: similar to ENSANGP00000025535; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to ENSANGP00000025535 - Nasonia vitripennis Length = 254 Score = 64.9 bits (151), Expect = 8e-10 Identities = 42/146 (28%), Positives = 76/146 (52%), Gaps = 6/146 (4%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 196 W KV +TGA+ GIG ++V LLD G + ++ +A K ++ ++ + K Sbjct: 4 WAGKVAVVTGASVGIGAAIVNKLLDNG---LIVVGLARRVEKVKEL-IDDRPEAKLHAVE 59 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITS 358 DVT+EE+ + + + G +DV++NNA L + S+ ++ ++VNV L Sbjct: 60 CDVTNEENVVTAFAWIKENLGSVDVLVNNAGVTKETTLSDGSLADWRNVLDVNVLGLCVC 119 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVA 436 T +A+ M + G +I++SS+A Sbjct: 120 TREAVRSMRECDG--ESVIIHISSLA 143 >UniRef50_Q89KQ8 Cluster: Blr4846 protein; n=2; Proteobacteria|Rep: Blr4846 protein - Bradyrhizobium japonicum Length = 255 Score = 64.9 bits (151), Expect = 8e-10 Identities = 48/143 (33%), Positives = 71/143 (49%), Gaps = 5/143 (3%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 202 D+VV ITG A+GIG + VR +G + +A LDI E AG SL E+ + G F R D Sbjct: 11 DRVVLITGGASGIGAAFVRAFAAQGAR-VAFLDIDEAAGGSLVEEVAAASGAAPLFVRCD 69 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK----- 367 + D + + V G V++NNAA ND + + +I LK Sbjct: 70 LLDIDALRAAIAQVRGSLGDAAVLVNNAA--NDQRQVLAEVTPSEFDWMIGVNLKHVFFA 127 Query: 368 AIEIMGKHSGGKGGTVINVSSVA 436 A ++ + GG++IN+SS+A Sbjct: 128 AQAVVPQMQARGGGSIINMSSIA 150 >UniRef50_Q7MBD9 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=17; Bacteria|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Chromobacterium violaceum Length = 246 Score = 64.9 bits (151), Expect = 8e-10 Identities = 43/147 (29%), Positives = 77/147 (52%), Gaps = 6/147 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K KV ITG+A+GIG++ + EG +A+ D+ +A K++ EL + G + Y+ Sbjct: 4 KGKVSIITGSASGIGKATAEKFVKEGAI-VAVCDLNPDAVKTVVDELKA-LGGEAYGYKV 61 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 361 DVTD+ ++ + G IDV++NNA ++ D+ I + K I++N+ + Sbjct: 62 DVTDKGQIAEMVADLKNRCGRIDVLVNNAGIVQDAQLIKMSEDQFDKVIDINLKGVYNCA 121 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAAL 442 ++ M + GG ++N SSV + Sbjct: 122 RAVVDTMVEQG---GGVILNASSVVGV 145 >UniRef50_Q46PX5 Cluster: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR - Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) Length = 253 Score = 64.9 bits (151), Expect = 8e-10 Identities = 44/145 (30%), Positives = 76/145 (52%), Gaps = 7/145 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 KDKV +TG A+GIGE+ VR+ +G + I D G+ L EL S+ + Sbjct: 9 KDKVAIVTGGASGIGEATVRLFASQGAS-VVIAD-RSALGEKLAREL-SESSLAAHYSEV 65 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITS 358 DV+ E+ +++ V G +D+++ NA + + S + +++ I+VN+T + S Sbjct: 66 DVSREDDTRRLIDDTVSRFGRLDIMVANAGIAHPSAPVEDVSVEQWQQMIDVNLTGVFLS 125 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSV 433 AI M K G GG ++N++S+ Sbjct: 126 NKLAIVQMKKQ--GTGGAIVNMASI 148 >UniRef50_Q1Q261 Cluster: Strongly similar to 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Strongly similar to 3-oxoacyl-[acyl-carrier protein] reductase - Candidatus Kuenenia stuttgartiensis Length = 239 Score = 64.9 bits (151), Expect = 8e-10 Identities = 40/145 (27%), Positives = 80/145 (55%), Gaps = 7/145 (4%) Frame = +2 Query: 32 VFITGAATGIGESVVRILLDEG----VKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 + +TG + GIG+++ ++ + EG V H +D E+ L+ E +S G+ + ++ Sbjct: 1 MLVTGGSKGIGKAICKVFIGEGDHVIVNHCKPIDDIEK----LREEFSSPQGSFS-IEKA 55 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVN--VTALITSTLKAI 373 DVTD +++ +V++ G IDV+INNA ++ D + A + N + +T Sbjct: 56 DVTDYAQIKQMVDNIVKKHGKIDVLINNAGIIKDGYIMLMSAKDWNDVINVNLTGVFNCT 115 Query: 374 EIMGKHS-GGKGGTVINVSSVAALT 445 + + +H G + GT+IN++S++ +T Sbjct: 116 KAVSEHMIGQRSGTIINIASLSGIT 140 >UniRef50_Q11C03 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Mesorhizobium sp. BNC1|Rep: Short-chain dehydrogenase/reductase SDR - Mesorhizobium sp. (strain BNC1) Length = 257 Score = 64.9 bits (151), Expect = 8e-10 Identities = 43/141 (30%), Positives = 74/141 (52%), Gaps = 5/141 (3%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS-D 202 KV +TGAA G+GE++ L +G + +A+LD+ +E G + + GN +YR+ D Sbjct: 7 KVALVTGAARGLGEAIAVELAAQGAR-VALLDVLDELGAEVAENIKKSSGN--AYYRNCD 63 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEV--NVTALITSTLKAI- 373 + D E ++ V G +DV++NNAA+ I + + E N+ + S++ Sbjct: 64 IRDTEEVRSAVDEVYSTYGKLDVLVNNAAVSTAPTSIPELSEETWNNIFNVNVSSIYRFC 123 Query: 374 -EIMGKHSGGKGGTVINVSSV 433 ++ + GG VIN+SSV Sbjct: 124 RFVLPRMQEAGGGAVINMSSV 144 >UniRef50_A5P2C8 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Methylobacterium sp. 4-46 Length = 255 Score = 64.9 bits (151), Expect = 8e-10 Identities = 45/149 (30%), Positives = 73/149 (48%), Gaps = 6/149 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TG A GIG + R +EG + + DI EAG + N + +F DV Sbjct: 7 KVALVTGGARGIGLATARRFAEEGAAAVILADIDAEAG-ARAAATNPVF----RFAPLDV 61 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAAL----MNDSIGI--YKKAIEVNVTALITSTLK 367 T + + + V +GG+DVV+N A + +S+ + +++ VNV Sbjct: 62 TQDAAWQDATDEAVAREGGLDVVVNCAGIAVVATIESVTLEQWRRVQAVNVDGTFLGCRH 121 Query: 368 AIEIMGKHSGGKGGTVINVSSVAALTQSH 454 A+ +M K G+GG +IN+SSV+ + H Sbjct: 122 AVRVM-KPPAGRGGAIINLSSVSGIIGGH 149 >UniRef50_A3XPR1 Cluster: Cyclohexanol dehydrogenase; n=1; Leeuwenhoekiella blandensis MED217|Rep: Cyclohexanol dehydrogenase - Leeuwenhoekiella blandensis MED217 Length = 261 Score = 64.9 bits (151), Expect = 8e-10 Identities = 44/149 (29%), Positives = 77/149 (51%), Gaps = 8/149 (5%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-YR 196 KD+V+ ITGAA G+G + +L EG K + ++D E A K + +L + Sbjct: 2 KDQVIIITGAAMGLGLATAELLAKEGAK-LVLVDYNENALKDAEQKLKEINPEVALLSVK 60 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINN-------AALMNDSIGIYKKAIEVNVTALIT 355 +DV+ EE ++ V++ G ID + NN A++++ + I+KK I++N+ + Sbjct: 61 ADVSSEEQVKNYVDKTVEKFGRIDGLYNNAGIEGKQASIVDYDLDIFKKVIDINLMGVYY 120 Query: 356 STLKAIEIMGKHSGGKGGTVINVSSVAAL 442 I +M K K G ++NV+SV + Sbjct: 121 GLRYVIPVMQKQ---KFGRIVNVASVGGI 146 >UniRef50_P50198 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=4; Sphingomonas|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Pseudomonas paucimobilis (Sphingomonas paucimobilis) Length = 250 Score = 64.9 bits (151), Expect = 8e-10 Identities = 47/145 (32%), Positives = 74/145 (51%), Gaps = 6/145 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV ITG A+G+G + + +EG K + I D+ EE K + E+ + G F R DV Sbjct: 8 KVALITGGASGLGAAQAKRFAEEGAK-VVIGDLNEEMAKGVVAEIRAA-GGDALFIRLDV 65 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLK 367 TD + + A V GG+ + N A +++ +SI + K + VN TA+ Sbjct: 66 TDAASWNNAIAAAVDGFGGLTTLSNTAGIIHPGGFEEESIEGWNKMVAVNQTAIFLGIKA 125 Query: 368 AIEIMGKHSGGKGGTVINVSSVAAL 442 AI + K SG G++IN+SS+ + Sbjct: 126 AIPELVK-SG--NGSIINISSLIGM 147 >UniRef50_Q39TG1 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Geobacter metallireducens GS-15|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 266 Score = 64.5 bits (150), Expect = 1e-09 Identities = 44/145 (30%), Positives = 76/145 (52%), Gaps = 6/145 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K +TGAA GIG ++ + L + G + I DI EA + + L+S K K SD Sbjct: 18 KRAVVTGAAAGIGYAIAKRLAEAGAT-VLITDINREAIEEAEHRLSSMKC-KVKSLVSDA 75 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLK 367 E + + V GG+D+++NNA +++ S+ +++ I +N+ + + + Sbjct: 76 GREADIKSLFSYVADSFGGVDILVNNAGIYPATKILDMSLEQWREVIRINLESAFLCSQE 135 Query: 368 AIEIMGKHSGGKGGTVINVSSVAAL 442 A IM + G GG ++N+SS+AAL Sbjct: 136 AGRIMVRQ--GTGGVIVNISSMAAL 158 >UniRef50_Q0LPB7 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Short-chain dehydrogenase/reductase SDR precursor - Herpetosiphon aurantiacus ATCC 23779 Length = 247 Score = 64.5 bits (150), Expect = 1e-09 Identities = 41/149 (27%), Positives = 78/149 (52%), Gaps = 7/149 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TG A GIG + ++L +G + I DI E+ G + ++ G + F DV Sbjct: 5 KVAIVTGGAIGIGAATAQLLAKQGAI-VVIGDINEQTGLATVEQIRGNAG-QAYFRHCDV 62 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALITSTL 364 + E ++ + +QGG+D++INNA + ++ ++ +++++T + Sbjct: 63 SHEADIQALVQFAL-DQGGLDIMINNAGIGGKPAPLHLTENHNWQRVLDIDLTGVFWGQK 121 Query: 365 KAIEIMGKHSGGKGGTVINVSSVAALTQS 451 A + M +GGKGG ++NV+S+A + S Sbjct: 122 YASQAM--LAGGKGGAIVNVASIAGVAGS 148 >UniRef50_UPI0000518CA5 Cluster: PREDICTED: similar to antdh CG1386-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to antdh CG1386-PA - Apis mellifera Length = 246 Score = 64.1 bits (149), Expect = 1e-09 Identities = 49/146 (33%), Positives = 76/146 (52%), Gaps = 6/146 (4%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 196 W KV +TGA+ GIG ++V+ LL G+ +A L E K L+ L G K Sbjct: 4 WAGKVAVVTGASAGIGAAIVKQLLTHGMV-VAGLARRVEKIKELEQGLEECTG-KLYAVE 61 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITS 358 DV+ EE + V + G +V+INNA + +S I ++ +VNV L Sbjct: 62 CDVSKEESVIAAFAWVQENLGPANVLINNAGITKESSLIDGNLEDWRSVFDVNVFGLCLC 121 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVA 436 T +AI +M + +GG+ G +IN++S+A Sbjct: 122 TKEAIRMM-RETGGE-GVIININSLA 145 >UniRef50_Q5LMX2 Cluster: 20-beta-hydroxysteroid dehydrogenase, putative; n=25; Alphaproteobacteria|Rep: 20-beta-hydroxysteroid dehydrogenase, putative - Silicibacter pomeroyi Length = 250 Score = 64.1 bits (149), Expect = 1e-09 Identities = 48/148 (32%), Positives = 74/148 (50%), Gaps = 8/148 (5%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K K V ITGA+ GIG R+ G ++ +L + EA + E+ G++ Sbjct: 5 KGKTVLITGASRGIGAEAGRVFAQAGA-NVVLLARSAEALAAQAAEI----GDRALALAC 59 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM--------NDSIGIYKKAIEVNVTALIT 355 DV D G +NA V GG+DV+INNA ++ +D +G + AI++N+ + Sbjct: 60 DVADAAQVAGAVNAAVSRFGGLDVLINNAGVIEPISHLASSDPVG-WGHAIDINLKGVYY 118 Query: 356 STLKAIEIMGKHSGGKGGTVINVSSVAA 439 A+ +M K GGT++ VSS AA Sbjct: 119 GMRAALPVMRK---AGGGTILTVSSGAA 143 >UniRef50_Q0S5L2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=3; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Rhodococcus sp. (strain RHA1) Length = 258 Score = 64.1 bits (149), Expect = 1e-09 Identities = 43/146 (29%), Positives = 70/146 (47%), Gaps = 6/146 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K + +TG A GIG ++V+ EG + D+ EE G+ + E + +F R D+ Sbjct: 6 KRILVTGGAQGIGAAIVKAYAMEGAT-VRSYDLNEEGGRVVAEEASDAGPGVVEFSRLDI 64 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIG------IYKKAIEVNVTALITSTLK 367 TD + + + +E GGIDV++N A L ++ +++ VNV I + Sbjct: 65 TDGDATESLFRSAARELGGIDVLVNIAGLQRSAMAEEITDDLFESIYRVNVLGTIHTNQS 124 Query: 368 AIEIMGKHSGGKGGTVINVSSVAALT 445 A IM S G G +IN S++ T Sbjct: 125 AYRIM--QSAGT-GAIINFGSMSGFT 147 >UniRef50_Q0C3P2 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=1; Hyphomonas neptunium ATCC 15444|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Hyphomonas neptunium (strain ATCC 15444) Length = 262 Score = 64.1 bits (149), Expect = 1e-09 Identities = 41/144 (28%), Positives = 70/144 (48%), Gaps = 2/144 (1%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 196 +++KV ITGAA+GIG + R+L EG H+ + D+ + GKS+ +L G + Sbjct: 6 FENKVAVITGAASGIGAATARLLAREGA-HVVLADVNDNGGKSIAADL----GPTAMAVK 60 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSIGIYKKAIEVNVTALITSTLKA 370 DV+ ++ A V+ G ID++ NNA + S+ I E + + S A Sbjct: 61 CDVSSAAEVEALVKAAVERHGRIDILFNNAGIGSFGTSVEIQPAEWERVIAIDLHSVYYA 120 Query: 371 IEIMGKHSGGKGGTVINVSSVAAL 442 H +G ++N +S++ L Sbjct: 121 CHFAIPHM-PRGSAIVNTASISGL 143 >UniRef50_A6EGH2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=1; Pedobacter sp. BAL39|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Pedobacter sp. BAL39 Length = 248 Score = 64.1 bits (149), Expect = 1e-09 Identities = 44/151 (29%), Positives = 76/151 (50%), Gaps = 7/151 (4%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 202 +KV ITGAA G+GES R + EG K + + D++ EAG+ L EL G F + D Sbjct: 6 NKVAIITGAAQGMGESHARTFVAEGAK-VILTDVSAEAGQKLADEL----GENAIFIKHD 60 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITST 361 VT E + ++ + G ++V++NNA ++ + Y K ++N ++ Sbjct: 61 VTCSEQWAHVVAEAEKAFGHVNVLVNNAGILGPMVKTQELQEADYLKVCDINQHSVFYGM 120 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAALTQSH 454 I M K G+++N+SS+A + ++ Sbjct: 121 KAVIPSMIK---AGIGSIVNISSIAGIVANY 148 >UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reductase; n=1; Bacillus sp. SG-1|Rep: 3-oxoacyl-(Acyl-carrier-protein) reductase - Bacillus sp. SG-1 Length = 246 Score = 64.1 bits (149), Expect = 1e-09 Identities = 43/147 (29%), Positives = 76/147 (51%), Gaps = 6/147 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K+K ITG+A GIG + + EG K + + D E G + + E + G T FY+ Sbjct: 4 KNKTAVITGSANGIGLAAAKKFAQEGCK-VIMADYDENKGAA-EAEKLQEEGGDTVFYQV 61 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITST 361 DV + E + V+++ G ID++INNA + D++ +++ ++VN+T + T Sbjct: 62 DVANRESVDNLAAWVLRDYGSIDILINNAGITRDALMAKMREDDFQRVLDVNLTGVFHCT 121 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAAL 442 + + + GK G +IN +S + L Sbjct: 122 QALLPAL--INSGK-GKIINTASASGL 145 >UniRef50_A3I573 Cluster: Short chain dehydrogenase; n=2; Bacillus sp. B14905|Rep: Short chain dehydrogenase - Bacillus sp. B14905 Length = 252 Score = 64.1 bits (149), Expect = 1e-09 Identities = 44/156 (28%), Positives = 75/156 (48%), Gaps = 7/156 (4%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 193 E +K+ +TGA +GIG + L G K + I+D +E G+ ++L + G + F Sbjct: 2 EHLNKIAVVTGAGSGIGRASSLKLASNGAK-VVIVDFNKETGEET-LKLVKEQGGEGIFV 59 Query: 194 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALI 352 ++DV+ E +NA V+ G IDV NNA ++ + Y + + +NV + Sbjct: 60 QADVSKSEDVEKYVNAAVETYGRIDVFFNNAGVIQKISPLTEIADSEYDRIMSINVKGVF 119 Query: 353 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSHVM 460 I++M G G++IN +S A + H M Sbjct: 120 LGLKHVIKVM---EGQGSGSIINTASTAGVRSEHSM 152 >UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Chloroflexus|Rep: Short-chain dehydrogenase/reductase SDR - Chloroflexus aggregans DSM 9485 Length = 256 Score = 64.1 bits (149), Expect = 1e-09 Identities = 46/149 (30%), Positives = 77/149 (51%), Gaps = 6/149 (4%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 193 E++ KV +TG A GIG + L EG + I D + A + VE + +G + Sbjct: 2 EFQGKVAIVTGGAQGIGRATALALAREGAA-VVIAD-RDAAATTALVEGINAWGGRALAV 59 Query: 194 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALIT 355 +DV+DE I N V E GGID+++NNA + + ++ ++++ I VN+T + Sbjct: 60 IADVSDESDAARIANDTVLEFGGIDLLVNNAGIQQPGTIESTTLQLWQEIINVNLTGVF- 118 Query: 356 STLKAIEIMGKHSGGKGGTVINVSSVAAL 442 L + +M + GG ++NV+SV L Sbjct: 119 --LVSRFVMPELRRRGGGAIVNVASVYGL 145 >UniRef50_Q2UEK6 Cluster: Dehydrogenases with different specificities; n=2; Aspergillus|Rep: Dehydrogenases with different specificities - Aspergillus oryzae Length = 261 Score = 64.1 bits (149), Expect = 1e-09 Identities = 42/142 (29%), Positives = 74/142 (52%), Gaps = 7/142 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TGA +GIG L + G ++ + + E GK +++++ G++ F +DV Sbjct: 13 KVAIVTGAGSGIGRETALCLANAGA-NVVVAEANETTGKETAAKVSAQTGSRGLFILTDV 71 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 364 + E ++ A ++ G +D+ +NNAAL D+ I ++K I VN+ + L Sbjct: 72 SRSESVQAMVIATIEAFGRLDIAVNNAALHPDASPIAELHEDHWQKIIGVNLVG-VAFCL 130 Query: 365 KAIEIMGKHSGGKGGTVINVSS 430 K E+ G GG++IN+SS Sbjct: 131 K-WELQQMIQQGGGGSIINISS 151 >UniRef50_Q9UY54 Cluster: Short-chain alcohol dehydrogenase, putative glucose-1-dehydrogenase; n=1; Pyrococcus abyssi|Rep: Short-chain alcohol dehydrogenase, putative glucose-1-dehydrogenase - Pyrococcus abyssi Length = 240 Score = 64.1 bits (149), Expect = 1e-09 Identities = 44/148 (29%), Positives = 75/148 (50%), Gaps = 7/148 (4%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 193 E K KV ITGA+ GIG ++ L GV + EE K + EL +YG +T Sbjct: 2 ELKGKVALITGASRGIGRAIAIELAKRGVNVVINYRSNEEEAKKTE-ELCRQYGVETLLV 60 Query: 194 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM---NDSIGI----YKKAIEVNVTALI 352 ++DV++ E ++ V+ + G ID++INNA ++ D + + + + I VN+ Sbjct: 61 KADVSNREEVREMVKKVIDKFGRIDILINNAGILGKTKDPLEVTDEEWDRVISVNLKGAF 120 Query: 353 TSTLKAIEIMGKHSGGKGGTVINVSSVA 436 T + + M K G ++N++S+A Sbjct: 121 IVTQEVLRYM------KKGKIVNIASIA 142 >UniRef50_Q9C826 Cluster: Xanthoxin dehydrogenase; n=41; Magnoliophyta|Rep: Xanthoxin dehydrogenase - Arabidopsis thaliana (Mouse-ear cress) Length = 285 Score = 64.1 bits (149), Expect = 1e-09 Identities = 45/148 (30%), Positives = 73/148 (49%), Gaps = 9/148 (6%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY-RSD 202 KV ITG ATGIGES+VR+ G K + I+D+ ++ G + L +T F+ D Sbjct: 21 KVALITGGATGIGESIVRLFHKHGAK-VCIVDLQDDLGGEVCKSLLRGESKETAFFIHGD 79 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAAL--------MNDSIGIYKKAIEVNVTALITS 358 V E+ ++ V+ G +D++INNA L N S+ ++ +VNV S Sbjct: 80 VRVEDDISNAVDFAVKNFGTLDILINNAGLCGAPCPDIRNYSLSEFEMTFDVNVKGAFLS 139 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVAAL 442 A +M K G+++++ SV + Sbjct: 140 MKHAARVMIPE---KKGSIVSLCSVGGV 164 >UniRef50_Q8F0K8 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=4; Leptospira|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Leptospira interrogans Length = 259 Score = 63.7 bits (148), Expect = 2e-09 Identities = 40/153 (26%), Positives = 82/153 (53%), Gaps = 7/153 (4%) Frame = +2 Query: 8 SHEWKDKVVFITGAAT--GIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNK 181 S +++ KV +TGAA+ G+G ++ + EG I ++D+ +E + ++ ++G K Sbjct: 6 SKQFEGKVALVTGAASPRGLGRAIANTIAKEG-GDIVLVDLNKEQIEQAAADVAKEFGVK 64 Query: 182 TKFYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITST 361 T +VT E ++ V ++ G +D ++NNA ++ D++ I + E ++ Sbjct: 65 TLGLSCNVTKPEDCDSVIAGVKEKFGKLDFLVNNAGVLKDNLFI--RMSEQEFDFVLDVN 122 Query: 362 LKAIEIMGKHSG-----GKGGTVINVSSVAALT 445 LK + +M K++ + G ++N+SSV+ LT Sbjct: 123 LKGVFLMTKYASKLLLKAESGRIVNISSVSGLT 155 >UniRef50_Q82GU5 Cluster: Putative dehydrogenase; n=1; Streptomyces avermitilis|Rep: Putative dehydrogenase - Streptomyces avermitilis Length = 258 Score = 63.7 bits (148), Expect = 2e-09 Identities = 42/146 (28%), Positives = 78/146 (53%), Gaps = 6/146 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 +VV I+GAA G GE R+ ++EG K + + D+ ++ G++L E+ ++Y DV Sbjct: 7 RVVLISGAARGQGEQEARLFVEEGAK-VVVADVLDDQGEALAKEIGARY------VHLDV 59 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALM--NDSIGI----YKKAIEVNVTALITSTLK 367 E+ + + G ID ++NNA ++ ND +G +++ ++VN + +K Sbjct: 60 GREDDWQAAVTVAKDAYGHIDGLVNNAGILRFNDLVGTPLAEFQQIVQVNQVGVFLG-IK 118 Query: 368 AIEIMGKHSGGKGGTVINVSSVAALT 445 + + +G GGT++N +S A LT Sbjct: 119 TVAPEIEAAG--GGTIVNTASYAGLT 142 >UniRef50_Q7VXT8 Cluster: Probable short-chain dehydrogenase; n=3; Bordetella|Rep: Probable short-chain dehydrogenase - Bordetella pertussis Length = 252 Score = 63.7 bits (148), Expect = 2e-09 Identities = 46/142 (32%), Positives = 76/142 (53%), Gaps = 7/142 (4%) Frame = +2 Query: 38 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTDEE 217 ITGAA GIG ++ R EG + + DI E G++L EL + G + +F R DVTDE+ Sbjct: 11 ITGAAVGIGAAMARRFCAEGAS-VLLGDIDAERGQALAAELAAT-GARARFARLDVTDED 68 Query: 218 HFLGILNAVVQEQGGIDVVINNA--ALMNDSIGIYKKAIE-----VNVTALITSTLKAIE 376 + E G + +++NNA + +ND + + A+E +N+ L+ + L Sbjct: 69 SVRQAMELAEAEHGPLHILVNNAGGSSLNDR-SVVEFALEEFWRAINID-LLGTVLCCRH 126 Query: 377 IMGKHSGGKGGTVINVSSVAAL 442 + + + GG V+N+ S+AAL Sbjct: 127 AIPRIAAAGGGAVVNMGSIAAL 148 >UniRef50_Q2W431 Cluster: Dehydrogenase with different specificities; n=2; Magnetospirillum|Rep: Dehydrogenase with different specificities - Magnetospirillum magneticum (strain AMB-1 / ATCC 700264) Length = 248 Score = 63.7 bits (148), Expect = 2e-09 Identities = 46/147 (31%), Positives = 75/147 (51%), Gaps = 6/147 (4%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 193 +++DKV ITG A+GIG V+ + + G + I DI EAG+ EL +K G K +F Sbjct: 2 KFEDKVALITGGASGIGYCTVKSMAELGA-DVLIADINVEAGEKAAAELTAK-GFKAEFV 59 Query: 194 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALIT 355 R DVTD+ + + VV +G +D++ N A +++ K + +N+T I Sbjct: 60 RLDVTDKANIARVKEHVVATRGRLDILCNVAGWGHIQPFVDNDDAFIAKVMSLNLTGPIE 119 Query: 356 STLKAIEIMGKHSGGKGGTVINVSSVA 436 +M + GK ++NV+S A Sbjct: 120 LIRAFFPLMIEKKTGK---IVNVASDA 143 >UniRef50_Q13H99 Cluster: Putative short-chain dehydrogenase/reductase; n=3; Proteobacteria|Rep: Putative short-chain dehydrogenase/reductase - Burkholderia xenovorans (strain LB400) Length = 274 Score = 63.7 bits (148), Expect = 2e-09 Identities = 43/149 (28%), Positives = 80/149 (53%), Gaps = 12/149 (8%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 ++KV +TGA G+G + R L G + +A++DI EA ++ ++ G + R+ Sbjct: 11 ENKVAIVTGAGAGLGAACARALAQHGAR-VAVVDINGEAAAAVAADI----GERAMSVRT 65 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------------SIGIYKKAIEVNVT 343 DV+ E +++AV++ G ID++ NNAA+++D S+ ++ +A+ VN+ Sbjct: 66 DVSSEAQVKAMVSAVLEHFGRIDILHNNAAVLDDAQRAGDRDVINMSVEVWDRAMAVNLR 125 Query: 344 ALITSTLKAIEIMGKHSGGKGGTVINVSS 430 + AI M + G GG++I+ SS Sbjct: 126 GAMLCCKHAIPAMLR---GGGGSIIHSSS 151 >UniRef50_Q0SU93 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=4; Clostridiales|Rep: 7-alpha-hydroxysteroid dehydrogenase - Clostridium perfringens (strain SM101 / Type A) Length = 253 Score = 63.7 bits (148), Expect = 2e-09 Identities = 48/149 (32%), Positives = 75/149 (50%), Gaps = 8/149 (5%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-YR 196 K+KVV +TG GIG + V+ LD G K +A+ +E ELN N + Sbjct: 9 KNKVVIVTGGTRGIGFATVKKFLDHGAK-VALCGSRKETVDKALEELNYINPNYDAIGFY 67 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIY-------KKAIEVNVTALIT 355 ++ D +++ V+++ G ID++INNA ++D+ IY K I++NV A+ Sbjct: 68 PNLLDSNEVKEMVDKVLEKWGTIDILINNAG-VSDNKSIYTQSDEDFSKIIDINVKAIFN 126 Query: 356 STLKAIEIMGKHSGGKGGTVINVSSVAAL 442 T EIM K G ++N SSV +L Sbjct: 127 CTKAVSEIM---KNKKYGVILNTSSVVSL 152 >UniRef50_A6W2S3 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Gammaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MWYL1 Length = 256 Score = 63.7 bits (148), Expect = 2e-09 Identities = 49/145 (33%), Positives = 74/145 (51%), Gaps = 7/145 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 KD+ VFI+G ATGIG ++V +G K A +D+ E+AG +L L +K G +F Sbjct: 13 KDRSVFISGGATGIGAAIVEAYAKQGAK-TAFVDLDEKAGTALAKRL-TKDGYDVRFEVC 70 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK---- 367 D+TD + + + A + G I V++NNAA ND + E L+ +K Sbjct: 71 DITDIQDYQSKIRAAAEVFGPITVLLNNAA--NDVRHSLESLTEERFDELVGVNIKHAMF 128 Query: 368 ---AIEIMGKHSGGKGGTVINVSSV 433 A+ M + G GG++IN SV Sbjct: 129 AAQAVAPMMRKLG--GGSIINFGSV 151 >UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bacterium HTCC2150|Rep: Dehydrogenase - Rhodobacterales bacterium HTCC2150 Length = 279 Score = 63.7 bits (148), Expect = 2e-09 Identities = 44/152 (28%), Positives = 77/152 (50%), Gaps = 5/152 (3%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDI-AEEAGKSLQVELNSKYGNKTKFYR 196 K+K V +TGAA G+G + L +G ++ + D+ AE+ +S+Q + ++ Sbjct: 23 KNKTVIVTGAAQGLGYACALRFLQDGA-NVVMADVNAEKLAESVQDLI--EFDGAVSSMV 79 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNA--ALMNDSIGIYKKAIEVNVTALITSTLKA 370 DVT E+ ++ V G +DV+INNA A + D + I + + + Sbjct: 80 CDVTKRENLQALVGLAVSNYGNLDVMINNAGIAKVQDFLEISDDEYDAVMDVNLRGAFIG 139 Query: 371 IEIMGKH--SGGKGGTVINVSSVAALTQSHVM 460 +I GK + GKGG +IN+SS+ AL + ++ Sbjct: 140 TQIAGKQMIAQGKGGVIINMSSINALVANPML 171 >UniRef50_A3IK59 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=2; Chroococcales|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Cyanothece sp. CCY 0110 Length = 250 Score = 63.7 bits (148), Expect = 2e-09 Identities = 45/143 (31%), Positives = 75/143 (52%), Gaps = 6/143 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K+ ITGA++GIGE++ L++E + + E+ K L L K +K + D+ Sbjct: 9 KIALITGASSGIGEAIAYRLVEENYRLVVCARRQEKLNK-LTETLREK-NSKILSLKVDL 66 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLK 367 E + + N + + GG+DV+INNA LM +++ +EVNV AL T + Sbjct: 67 RQEAEIMNMFNTIRDKWGGVDVLINNAGLGHKEPLMIGETEAWREMLEVNVLALCICTRE 126 Query: 368 AIEIMGKHSGGKGGTVINVSSVA 436 AI+ M S G +I++SS++ Sbjct: 127 AIKDM---SDRNEGHIIHISSMS 146 >UniRef50_Q965D6 Cluster: 3-oxoacyl-acyl-carrier protein reductase precursor; n=8; Plasmodium|Rep: 3-oxoacyl-acyl-carrier protein reductase precursor - Plasmodium falciparum Length = 301 Score = 63.7 bits (148), Expect = 2e-09 Identities = 38/145 (26%), Positives = 76/145 (52%), Gaps = 3/145 (2%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 ++KV +TGA GIG + + +L + V H+ + +++ S+ E+ S +G ++ Y Sbjct: 59 ENKVALVTGAGRGIGREIAK-MLAKSVSHVICISRTQKSCDSVVDEIKS-FGYESSGYAG 116 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE---VNVTALITSTLKA 370 DV+ +E ++N ++ E +D++++NA + D++ + K E V T L + Sbjct: 117 DVSKKEEISEVINKILTEHKNVDILVSNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYIT 176 Query: 371 IEIMGKHSGGKGGTVINVSSVAALT 445 I + + G +IN+SS+ LT Sbjct: 177 QPISKRMINNRYGRIINISSIVGLT 201 >UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59; cellular organisms|Rep: Acetoin(diacetyl) reductase - Klebsiella pneumoniae Length = 256 Score = 63.7 bits (148), Expect = 2e-09 Identities = 44/143 (30%), Positives = 69/143 (48%), Gaps = 6/143 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TGA GIG+++ L+ +G +AI D + K++ E+N G + + DV Sbjct: 3 KVALVTGAGQGIGKAIALRLVKDGFA-VAIADYNDATAKAVASEINQA-GGRAMAVKVDV 60 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMN----DSI--GIYKKAIEVNVTALITSTLK 367 +D + + + GG DV++NNA + +SI I K +NV +I Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQA 120 Query: 368 AIEIMGKHSGGKGGTVINVSSVA 436 A+E K G GG +IN S A Sbjct: 121 AVEAFKKE--GHGGKIINACSQA 141 >UniRef50_UPI00015B452D Cluster: PREDICTED: similar to ENSANGP00000021713; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to ENSANGP00000021713 - Nasonia vitripennis Length = 247 Score = 63.3 bits (147), Expect = 2e-09 Identities = 46/145 (31%), Positives = 74/145 (51%), Gaps = 6/145 (4%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 196 W+ KV +TGAA+GIG S+ R LLD G+ + LD+ E LQ + + R Sbjct: 4 WRGKVALVTGAASGIGASISRRLLDAGLVVVG-LDVQIEPMLELQSQNQGFHA-----IR 57 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITS 358 DV+ EE + V E G + V++NNA + N + I +++ I +NV A+ + Sbjct: 58 CDVSREEELVRAFKKVDSEIGQLQVMVNNAGITNYTPIIESDRQTFERMININVLAMASC 117 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSV 433 KA+++M + G + N +SV Sbjct: 118 ISKAVQMM--RANKVEGHIFNTNSV 140 >UniRef50_Q62E12 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=25; Proteobacteria|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Burkholderia mallei (Pseudomonas mallei) Length = 265 Score = 63.3 bits (147), Expect = 2e-09 Identities = 42/149 (28%), Positives = 79/149 (53%), Gaps = 8/149 (5%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG-KSLQVELNSKYGNKTKFYR-S 199 K FITGAA G+G ++ R + ++G + + + DI + A ++ ELN G + + Sbjct: 14 KRAFITGAAGGLGRAIARRMAEQGAQ-VFLTDIVDAAVLEAFAAELNDTAGERIAWAAVQ 72 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN-DSIG-----IYKKAIEVNVTALITST 361 DV DE + L+ GG+ V+++NA + + +IG +++ + +NV +++ T Sbjct: 73 DVADEAQWASRLSQAADAMGGLSVLVHNAGVGSFGAIGQIARDEWRRVMAINVESIVLGT 132 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAALTQ 448 A+ + G +++N+SSVAA Q Sbjct: 133 KHALPYL---EAGAPASIVNISSVAAFKQ 158 >UniRef50_Q3WJ78 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Frankia sp. EAN1pec|Rep: Short-chain dehydrogenase/reductase SDR - Frankia sp. EAN1pec Length = 250 Score = 63.3 bits (147), Expect = 2e-09 Identities = 40/147 (27%), Positives = 77/147 (52%), Gaps = 7/147 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TGAA GIG ++ + EG K + I DI + G+ + EL G + F+ +DV Sbjct: 10 KVAIVTGAANGIGVAIATRFVTEGAK-VVIADI-DAGGQGVAAEL----GERATFFSTDV 63 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAAL-------MNDSIGIYKKAIEVNVTALITSTL 364 +D +++ ++ GG+ V+ NNA + ++D + +++ + V++ ++ + Sbjct: 64 SDPVQTQALVDFTIRHFGGLHVLCNNAGVSGGLRRFLDDDLRDFERVVAVDLYGVMACSR 123 Query: 365 KAIEIMGKHSGGKGGTVINVSSVAALT 445 A M H GG ++N++S A +T Sbjct: 124 SAARHMVDHG---GGAIVNIASGAGIT 147 >UniRef50_Q1GUT7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Sphingopyxis alaskensis (Sphingomonas alaskensis) Length = 286 Score = 63.3 bits (147), Expect = 2e-09 Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 6/144 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 + F+TG GIG ++ I L E ++AILDI E + + G + + +DV Sbjct: 10 QAAFVTGGGGGIGRAIA-IRLAEAGANVAILDIIAERAEETATRIRET-GARALTFPADV 67 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITSTLK 367 + + ++ G +D+++NNA + S +K I++N+ +++ +T Sbjct: 68 MESDALRAAIDQAAAAFGRLDILVNNAGGVSARPFLEQSERSMRKHIDINLMSMLVATQA 127 Query: 368 AIEIMGKHSGGKGGTVINVSSVAA 439 A M +GGKGG++INV+S+ A Sbjct: 128 AARHMV--AGGKGGSIINVASIEA 149 >UniRef50_A4VH60 Cluster: 3-hydroxyacyl-CoA dehydrogenase FadB2x; n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase FadB2x - Pseudomonas stutzeri (strain A1501) Length = 258 Score = 63.3 bits (147), Expect = 2e-09 Identities = 50/154 (32%), Positives = 74/154 (48%), Gaps = 14/154 (9%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 +DKVV ITG A+G+G + L E IAI D+ EAG+ L ++ + F + Sbjct: 4 QDKVVVITGGASGLGLATAHYLAAEKGARIAIFDLNVEAGEQAVAALGTE---RAMFVAT 60 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND-----------SIGIYKKAIEVNVTA 346 DV+ EE ++AV+ G I V IN AA+ + + +A +N+ Sbjct: 61 DVSSEESVQNAVDAVMANFGAIHVCINGAAVPTGFKILGKEGKAAPLARFAQATAINLNG 120 Query: 347 LITSTLKAIEIMGKH---SGGKGGTVINVSSVAA 439 + K E M K+ +G + G VINVSS AA Sbjct: 121 VFNVMSKCAEHMAKNEAEAGEERGVVINVSSGAA 154 >UniRef50_P50197 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase; n=8; root|Rep: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase - Pseudomonas paucimobilis (Sphingomonas paucimobilis) Length = 250 Score = 63.3 bits (147), Expect = 2e-09 Identities = 39/146 (26%), Positives = 75/146 (51%), Gaps = 7/146 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K + +TG +GIG + V +L+ G ++ + DI +EAG+++ + G K ++R D+ Sbjct: 7 KTIIVTGGGSGIGRATVELLVASGA-NVPVADINDEAGEAVV----ATSGGKAAYFRCDI 61 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 364 EE ++ + GG+D NNAA L S+ +++++++NVT T Sbjct: 62 AQEEDVKALVAQTLAAFGGLDGSFNNAAIPQAGLPLAEVSLERFRQSMDINVTG--TFLC 119 Query: 365 KAIEIMGKHSGGKGGTVINVSSVAAL 442 +I+ G G+++N +S A + Sbjct: 120 MKYQILAMIERGTKGSIVNTASAAGV 145 >UniRef50_P33207 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplast precursor; n=80; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase, chloroplast precursor - Arabidopsis thaliana (Mouse-ear cress) Length = 319 Score = 63.3 bits (147), Expect = 2e-09 Identities = 45/145 (31%), Positives = 76/145 (52%), Gaps = 7/145 (4%) Frame = +2 Query: 29 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELN-SKYGNKTKFYRSDV 205 VV ITGA+ GIG+++ L G K +++ A A ++ +V +YG + + DV Sbjct: 78 VVVITGASRGIGKAIALALGKAGCK--VLVNYARSAKEAEEVAKQIEEYGGQAITFGGDV 135 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 367 + ++ + + G IDVV+NNA + D++ I + + I +N+T + T Sbjct: 136 SKATDVDAMMKTALDKWGTIDVVVNNAGITRDTLLIRMKQSQWDEVIALNLTGVFLCTQA 195 Query: 368 AIEIMGKHSGGKGGTVINVSSVAAL 442 A++IM K K G +IN+SSV L Sbjct: 196 AVKIMMKK---KRGRIINISSVVGL 217 >UniRef50_Q9NAR7 Cluster: Alcohol dehydrogenase; n=23; Schizophora|Rep: Alcohol dehydrogenase - Bactrocera oleae (Olive fruit fly) Length = 258 Score = 63.3 bits (147), Expect = 2e-09 Identities = 41/140 (29%), Positives = 74/140 (52%), Gaps = 2/140 (1%) Frame = +2 Query: 29 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAG--KSLQVELNSKYGNKTKFYRSD 202 VVF+ G IG + ++ + V + D+ E A K+LQ +N K K + + D Sbjct: 8 VVFVGGLGF-IGYEACKQIMTKNVASFFVFDVLENAENIKALQA-INPK--TKVYYTKFD 63 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 382 +T++ V+ + IDV++N A ++ D + + +N+ LI +TL+AI +M Sbjct: 64 ITNKASIKSAFADVIAKVQYIDVLVNGAGILTDPN--VELTMNINLIGLINTTLEAIPLM 121 Query: 383 GKHSGGKGGTVINVSSVAAL 442 K+ G+GG ++N++SV L Sbjct: 122 DKNKKGRGGLIVNIASVLGL 141 >UniRef50_Q9KBT2 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=1; Bacillus halodurans|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Bacillus halodurans Length = 247 Score = 62.9 bits (146), Expect = 3e-09 Identities = 39/145 (26%), Positives = 71/145 (48%), Gaps = 7/145 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 +DKV +TGA GIG+ +V+ +++G I EA + ++ LN G K Y S Sbjct: 4 RDKVAIVTGATRGIGKEIVKTFVEQGAFVYGIYASNHEAAREIEKTLNQ--GEKCVSYVS 61 Query: 200 DVTDEEHFL-GILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 358 D++ F+ + +VV + +D+++NNA + D +++ ++VN T Sbjct: 62 GSVDDQLFIHSLFKSVVDKHNRLDILVNNAGITRDQFLFQMDDQSWQQVLQVNFGGTYTC 121 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSV 433 A+ M + GK V++V+ V Sbjct: 122 CHAALPYMERKKQGKIVNVVSVTGV 146 >UniRef50_Q929J7 Cluster: Lin2278 protein; n=14; Bacteria|Rep: Lin2278 protein - Listeria innocua Length = 253 Score = 62.9 bits (146), Expect = 3e-09 Identities = 37/147 (25%), Positives = 76/147 (51%), Gaps = 8/147 (5%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TGAA+G+G+ + + EG K + + D+ EA + + + G ++V Sbjct: 7 KVAVVTGAASGMGQQIAVLFAKEGAK-VVVADLNLEAAQKTVALIEDEQGTALAVV-ANV 64 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-------GIYKKAIEVNVTALITSTL 364 T ++ ++N + G +D+++NNA +M++ + ++ K +N T ++ +T Sbjct: 65 TKQDDIESMINKATETYGTLDILVNNAGIMDNFVPAGELTDELWDKVFAINTTGVMRATR 124 Query: 365 KAIEIMGKHSGGKG-GTVINVSSVAAL 442 KA+ I + KG G ++N++S L Sbjct: 125 KALHIFEE----KGQGVIVNIASAGGL 147 >UniRef50_Q88SD1 Cluster: Short-chain dehydrogenase/oxidoreductase; n=4; Bacteria|Rep: Short-chain dehydrogenase/oxidoreductase - Lactobacillus plantarum Length = 279 Score = 62.9 bits (146), Expect = 3e-09 Identities = 43/147 (29%), Positives = 77/147 (52%), Gaps = 8/147 (5%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 202 DKVV ITGA G+G +G K I ++D+ + ++ +L KYG +T + + Sbjct: 10 DKVVAITGAVGGMGTKFCEEFAKQGAK-IVLIDMIADKTEAYAKKLTEKYGVETLAVKCN 68 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTA--LITS 358 T+EE + AV + G +DV++N AA++ S + ++ A+ VN+T L++ Sbjct: 69 TTNEEEVDAAVKAVTDKFGEVDVLVNTAAILRFSPLEDLRLDEWQAALNVNLTGYFLMSQ 128 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVAA 439 + I KH G ++++S+VA+ Sbjct: 129 RFGRVMIQQKH-----GAMVHISTVAS 150 >UniRef50_Q81WX9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reductase, putative; n=10; Bacillus cereus group|Rep: 3-oxoacyl-(Acyl-carrier-protein) reductase, putative - Bacillus anthracis Length = 246 Score = 62.9 bits (146), Expect = 3e-09 Identities = 39/143 (27%), Positives = 75/143 (52%), Gaps = 6/143 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K +TGAA GIG+ + R+ G K + I D+ EE + EL + G + YR DV Sbjct: 7 KTAVVTGAAQGIGKEIARVYAKLGAK-VLISDVNEEKLQKTTRELLDE-GYEVSLYRCDV 64 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITSTLK 367 +++ ++ VQ+ G + +++NNA + D++ +++ ++VN+T + Sbjct: 65 SNQNEAKSLIEYAVQKFGTLHILVNNAGITRDAMLHKMEKSSWEQVLQVNLTGVFYCMQP 124 Query: 368 AIEIMGKHSGGKGGTVINVSSVA 436 A+ M + G+ +IN+SS++ Sbjct: 125 ALLYMRQQGYGR---IINISSIS 144 >UniRef50_Q2RLD2 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Moorella thermoacetica (strain ATCC 39073) Length = 253 Score = 62.9 bits (146), Expect = 3e-09 Identities = 46/148 (31%), Positives = 79/148 (53%), Gaps = 7/148 (4%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 196 ++ K+V+ITG++TGIG ++ G + + +E+A SL E+ + G K+ R Sbjct: 4 FEGKIVWITGSSTGIGRAMALGFARNGANVVIHYNNSEKAALSLAQEIE-QMGKKSLVVR 62 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALM-------NDSIGIYKKAIEVNVTALIT 355 DV+D+ +++ + + G IDV+INNA M ++ + I VN+ ++ Sbjct: 63 GDVSDKNQVDAMVSKIKERFGRIDVLINNAGSMIKRARFEEVDEALWDRIINVNLKSVFL 122 Query: 356 STLKAIEIMGKHSGGKGGTVINVSSVAA 439 T KA+ M K G G +IN++SVAA Sbjct: 123 VT-KAVFPMMKAQG--KGKIINITSVAA 147 >UniRef50_Q19890 Cluster: Putative uncharacterized protein; n=14; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 284 Score = 62.9 bits (146), Expect = 3e-09 Identities = 47/151 (31%), Positives = 72/151 (47%), Gaps = 12/151 (7%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE--EAGKSLQVELNSKYGNKTKFYR 196 DKV ITG++ GIG++ R+L EG K AE E K++ + GN Sbjct: 6 DKVAIITGSSNGIGQATARLLASEGAKVTVTGRNAERLEETKNILLGAGVPEGN-VLVVV 64 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL----------MNDSIGIYKKAIEVNVTA 346 D+T E ++ + + + G ID+++NNA +N SI Y K E+NV + Sbjct: 65 GDITQESVQENLIKSTLDKFGKIDILVNNAGAGIPDAQGKSGVNQSIDTYHKTFELNVQS 124 Query: 347 LITSTLKAIEIMGKHSGGKGGTVINVSSVAA 439 +I T KA H G ++N+SS+ A Sbjct: 125 VIEMTQKA----RPHLAKTQGEIVNISSIGA 151 >UniRef50_P40747 Cluster: Uncharacterized oxidoreductase yuxG; n=7; Bacteria|Rep: Uncharacterized oxidoreductase yuxG - Bacillus subtilis Length = 689 Score = 62.9 bits (146), Expect = 3e-09 Identities = 46/146 (31%), Positives = 68/146 (46%), Gaps = 7/146 (4%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKF 190 E+ KV ITG A GIG + R EG H+ + D+ E + + E+N YG + Sbjct: 424 EFSRKVALITGGAGGIGSAACRRFAAEG-GHVIVADLNIEGAQKIAGEINDAYGKGRAMA 482 Query: 191 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMN----DSIGIYKKAIEVNV--TALI 352 + DVT EE GGID+V+NNA L D + + + +NV T Sbjct: 483 VKMDVTKEEDVQSAFERAALAYGGIDIVVNNAGLATSSPFDETSLKEWNLNMNVLGTGYF 542 Query: 353 TSTLKAIEIMGKHSGGKGGTVINVSS 430 +A + M KH +GG+++ V S Sbjct: 543 LVAREAFKQM-KHQ-NRGGSMVFVGS 566 >UniRef50_A7IMM1 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=1; Xanthobacter autotrophicus Py2|Rep: Short-chain dehydrogenase/reductase SDR precursor - Xanthobacter sp. (strain Py2) Length = 261 Score = 62.5 bits (145), Expect = 4e-09 Identities = 42/146 (28%), Positives = 75/146 (51%), Gaps = 6/146 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 KDK + ITGAA GIG ++ + L +G + I + D++E A +++ E+ + G Sbjct: 5 KDKSIVITGAAGGIGAAIAKALAADGAR-ITVADLSEPAARAVAGEITAA-GGTAIAVAV 62 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 361 DV +L+ V G +DV+ NNA + ++ + ++ +VN ++ Sbjct: 63 DVRQRAQVRALLDEAVAAHGRLDVLFNNAGVAQTRPFLDITEDDWRFVTDVNALGVLIGM 122 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAA 439 +AI+ K GG GG ++N +S+AA Sbjct: 123 QEAIKTF-KRQGG-GGKIVNTASIAA 146 >UniRef50_A2ULL1 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Escherichia coli B|Rep: Short-chain dehydrogenase/reductase SDR - Escherichia coli B Length = 250 Score = 62.5 bits (145), Expect = 4e-09 Identities = 49/147 (33%), Positives = 78/147 (53%), Gaps = 7/147 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGN-KTKFYRSD 202 KVV +TG A GIG+ + + D G H I+D EE GK+ EL +G+ K+ F ++D Sbjct: 7 KVVLVTGGAHGIGKGIAKQFADRGA-HTVIVDYNEENGKATAAELT--FGDVKSLFIKTD 63 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTL 364 V+D + + + V G IDV+I NA + N S + K I +N++ L +T+ Sbjct: 64 VSDPQALVDVREKVFATFGRIDVLILNAGVAFANKVNNISFEEWNKTIAINLSGLF-NTV 122 Query: 365 KAIEIMGKHSGGKGGTVINVSSVAALT 445 KA K G+++ +SS +AL+ Sbjct: 123 KA--FYDDFLTNK-GSIVYISSGSALS 146 >UniRef50_A0TVU3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Burkholderia cenocepacia MC0-3|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia cenocepacia MC0-3 Length = 261 Score = 62.5 bits (145), Expect = 4e-09 Identities = 45/146 (30%), Positives = 74/146 (50%), Gaps = 8/146 (5%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSL--QVELNSKYGNKTKFYRS 199 KV +TGA +GIG +L G +A D+ EEA + Q+EL+S K + Sbjct: 14 KVAVVTGAGSGIGRETALLLASAGAAVVA-ADLNEEAAQETVKQIELSS---GKAIAVKV 69 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 361 D+ +E L + V + G +DV++NNA + + S + K + VN+ Sbjct: 70 DIGNESSILAMYETVQAKLGRLDVLVNNAGIYPKTHFVETSAEKWDKVLGVNLRGTFLCM 129 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAA 439 +AI+ M + G GG+++N+SSVA+ Sbjct: 130 REAIKRM--QATGNGGSIVNISSVAS 153 >UniRef50_Q22CU9 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family protein; n=1; Tetrahymena thermophila SB210|Rep: Oxidoreductase, short chain dehydrogenase/reductase family protein - Tetrahymena thermophila SB210 Length = 843 Score = 62.5 bits (145), Expect = 4e-09 Identities = 47/149 (31%), Positives = 75/149 (50%), Gaps = 6/149 (4%) Frame = +2 Query: 32 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 211 V +TGAA G G+ + + +I I DI E+ + E+ K G K FY+ DV+D Sbjct: 577 VLLTGAAMGAGKFLAMNFAKKNNCNIIIYDIREDLMGQVIEEIQ-KAGAKGYFYKCDVSD 635 Query: 212 EEHFLGILNAVVQEQGGIDVVINNAALMN------DSIGIYKKAIEVNVTALITSTLKAI 373 E+ + + +Q+ ID++INN + N S +KA VN A ++ K + Sbjct: 636 EQELQRTVESTLQKFQKIDILINNVGIANLKLFTDVSFDEVQKAFSVNFLAPVSIIKKIL 695 Query: 374 EIMGKHSGGKGGTVINVSSVAALTQSHVM 460 +M + + G ++NVSSVA+L S M Sbjct: 696 PVMIERNQGH---IVNVSSVASLMPSAKM 721 >UniRef50_Q49WS9 Cluster: Uncharacterized oxidoreductase SSP1627; n=13; Bacteria|Rep: Uncharacterized oxidoreductase SSP1627 - Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 /DSM 20229) Length = 246 Score = 62.5 bits (145), Expect = 4e-09 Identities = 47/146 (32%), Positives = 73/146 (50%), Gaps = 7/146 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYG-NKTKFYR 196 KDKVV ITGA++GIGE V +L + G K L + L+ ++ K G + + Sbjct: 5 KDKVVVITGASSGIGEETVNLLSENGAK----LVLGARRLDRLE-KIQQKVGHDSVSIKK 59 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 358 +DVT + ++ + G IDV+INNA LM S + + I+VN+ ++ Sbjct: 60 TDVTKPDEVNALIETAYNDFGRIDVLINNAGLMPQSFLEKNKQDEWNQMIDVNIKGVLYG 119 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVA 436 + M K K G +IN++SVA Sbjct: 120 IGAVLPYMRKQ---KSGHIINLASVA 142 >UniRef50_Q39TI0 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) Length = 258 Score = 62.1 bits (144), Expect = 6e-09 Identities = 43/145 (29%), Positives = 76/145 (52%), Gaps = 6/145 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TGAA+G+G + R+L EG + + I DI + G++L L G F R DV Sbjct: 7 KVAIVTGAASGLGAASARLLAREGAR-VVITDINVKDGQALANSL----GEGAIFLRHDV 61 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITSTLK 367 +DE ++ I+ + G +D+++NNA ++ + ++ ++ V Sbjct: 62 SDEAQWVAIIEQTLSRFGRLDILVNNAGVVVVADVEHTTVEDWRFVNAVGTDGTFFGCKH 121 Query: 368 AIEIMGKHSGGKGGTVINVSSVAAL 442 AI M + SG GG+++N+SS+A + Sbjct: 122 AIPAM-RRSG--GGSIVNLSSLAGI 143 >UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Marinomonas sp. MWYL1|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MWYL1 Length = 252 Score = 62.1 bits (144), Expect = 6e-09 Identities = 43/146 (29%), Positives = 73/146 (50%), Gaps = 7/146 (4%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDI-AEEAGKSLQVELNSKYGNKTKFYRS 199 +KVV +TGA+ GIG ++ L + G + I D+ EE G + K G K + + Sbjct: 6 NKVVLVTGASRGIGRALAEGLAEHGA-DVVICDLPREEKGLNEAKSAIEKLGRKCWVFGA 64 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITST 361 D+TD+ ++ ++ G IDV++NNA ++ S+ G + VN L+ T Sbjct: 65 DITDKSAVENMVAQATEQAGHIDVLVNNAGILKPSLLEDLSEGDWDAHFAVNGKGLLFVT 124 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAA 439 + M + K G +IN++S+AA Sbjct: 125 NAVLPQMRQR---KNGRIINIASIAA 147 >UniRef50_A0YA77 Cluster: Short-chain dehydrogenase/reductase; n=1; marine gamma proteobacterium HTCC2143|Rep: Short-chain dehydrogenase/reductase - marine gamma proteobacterium HTCC2143 Length = 264 Score = 62.1 bits (144), Expect = 6e-09 Identities = 45/145 (31%), Positives = 79/145 (54%), Gaps = 6/145 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV ITG +GIGE+ I + EG + + +EE G+++ ++ G+K + ++DV Sbjct: 8 KVAIITGGTSGIGEATADIYIKEGAT-VVLTGRSEEKGQAIA----NRLGDKAHYIKADV 62 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNA----ALMNDSI--GIYKKAIEVNVTALITSTLK 367 + EE ++ V+ G +DV+ NNA DSI G +++ +++++ Sbjct: 63 SKEEDIANTISETVERFGKLDVLFNNAGGPVGGTIDSIAPGDINYGVDLLLSSVVLGIRY 122 Query: 368 AIEIMGKHSGGKGGTVINVSSVAAL 442 AIE M K +G GG +IN +S+AA+ Sbjct: 123 AIEPM-KANG--GGVIINNTSIAAI 144 >UniRef50_A0QV78 Cluster: Cyclopentanol dehydrogenase; n=2; Bacteria|Rep: Cyclopentanol dehydrogenase - Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) Length = 355 Score = 62.1 bits (144), Expect = 6e-09 Identities = 46/145 (31%), Positives = 71/145 (48%), Gaps = 6/145 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV ITG A G GE+ R+ G H+ I D+ EE G+ L EL G + F DV Sbjct: 102 KVALITGGARGQGEAEARLFAQHGA-HVYICDVLEEEGEKLAAELRGS-GLQADFRFLDV 159 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAAL-----MNDSIG-IYKKAIEVNVTALITSTLK 367 TD E + + + G +DV+INNA + + D+ + + + VN + ++ Sbjct: 160 TDAEQWSRTVAHIDAGAGRLDVLINNAGINVRHQLTDTTSEEWDRIVAVNTKGQMLG-MQ 218 Query: 368 AIEIMGKHSGGKGGTVINVSSVAAL 442 A + K SG G++IN+ S A + Sbjct: 219 ACAPLMKRSG--NGSIINIGSTAGI 241 >UniRef50_Q9SBM0 Cluster: Wts2L; n=3; core eudicotyledons|Rep: Wts2L - Citrullus lanatus (Watermelon) (Citrullus vulgaris) Length = 273 Score = 62.1 bits (144), Expect = 6e-09 Identities = 41/127 (32%), Positives = 66/127 (51%), Gaps = 1/127 (0%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV ITG A+GIG S VRI + G K + I DI +E G+ + EL G+ + DV Sbjct: 16 KVAIITGGASGIGTSAVRIFHENGAK-VIIADIQDEIGQKIADEL----GDDVSYIHCDV 70 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI-GIYKKAIEVNVTALITSTLKAIEIM 382 + E+ +++A V G +D++ +NA +++ S GI ++VT + + +M Sbjct: 71 SKEDDVSNLVDAAVHRHGKLDIMYSNAGVLDRSFSGI------LDVTKSDLDKVLGVNVM 124 Query: 383 GKHSGGK 403 G G K Sbjct: 125 GAFWGAK 131 >UniRef50_Q9KEC1 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=2; Bacillus|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Bacillus halodurans Length = 252 Score = 61.7 bits (143), Expect = 8e-09 Identities = 41/144 (28%), Positives = 79/144 (54%), Gaps = 6/144 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 KDKVV +TG + GIG+ + + ++EG K +AI +A +A LQ E + GN ++ Sbjct: 6 KDKVVLVTGGSKGIGKGIAQAFVEEGAK-VAI--VARDA-HGLQ-EAKRQLGNVLTI-QA 59 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITST 361 DVTD+ + + +++ G ID+++NNA + + ++++A +N + + + Sbjct: 60 DVTDKNEREKVFSQLLETYGTIDILVNNAGGSNGGLISETELSLFEEAFSLNYFSAVHFS 119 Query: 362 LKAIEIMGKHSGGKGGTVINVSSV 433 A+ +M + G +IN+SS+ Sbjct: 120 QLALPVM---KAKQSGAIINISSI 140 >UniRef50_Q5WBM0 Cluster: Oxidoreductase; n=1; Bacillus clausii KSM-K16|Rep: Oxidoreductase - Bacillus clausii (strain KSM-K16) Length = 247 Score = 61.7 bits (143), Expect = 8e-09 Identities = 47/146 (32%), Positives = 75/146 (51%), Gaps = 6/146 (4%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 193 E +KVV ITG A+GIG + V L +G K + I D +E G++ EL G + F Sbjct: 3 ELTNKVVIITGGASGIGRAAVDAFLAKGAK-VVIADFNKETGEAAVKELTDA-GKQVLFV 60 Query: 194 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDS----IGIYKKAIEVNVTALIT 355 ++DV++E ++ V+ +D++INNA M+ S Y+K ++V + Sbjct: 61 QTDVSNEPSVQNMVAETVKAYERVDILINNAGFGTMSPSHERTYEDYEKIVKVCQDGVFL 120 Query: 356 STLKAIEIMGKHSGGKGGTVINVSSV 433 + AI+ M K GG +IN SS+ Sbjct: 121 GSKHAIKEMIKTG---GGCIINTSSI 143 >UniRef50_Q5L166 Cluster: Oxidoreductase; n=8; Bacteria|Rep: Oxidoreductase - Geobacillus kaustophilus Length = 260 Score = 61.7 bits (143), Expect = 8e-09 Identities = 42/149 (28%), Positives = 76/149 (51%), Gaps = 6/149 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K +TG G+GE + L + G ++ + EA + ++ +L + G ++ R DV Sbjct: 12 KTAIVTGGGRGLGEQIAVGLAEAGA-NVVVCSRKVEACEQVKEKLE-QLGVRSLALRCDV 69 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINN------AALMNDSIGIYKKAIEVNVTALITSTLK 367 T+ E ++ V+E GGID+++NN A + + ++K I VNVT + Sbjct: 70 TNPEEVKHVVETTVKEFGGIDILVNNSGATWGAPVEEMPLEAWQKVINVNVTGTFLMSQA 129 Query: 368 AIEIMGKHSGGKGGTVINVSSVAALTQSH 454 ++M + GG++IN++SVA L +H Sbjct: 130 VGKVM--IAKQTGGSIINIASVAGLGGTH 156 >UniRef50_Q0LUS2 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Caulobacter sp. K31|Rep: Short-chain dehydrogenase/reductase SDR - Caulobacter sp. K31 Length = 254 Score = 61.7 bits (143), Expect = 8e-09 Identities = 46/144 (31%), Positives = 75/144 (52%), Gaps = 6/144 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K KV ITGAA G+GE++ R + G + I D+ E G+++ ++ ++ G K F Sbjct: 8 KGKVAIITGAAQGLGEAIAREFVARGAA-VIITDVQREEGEAVAADILAQ-GGKALFIAH 65 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITST 361 DV D E + ++ + G +DV++NNA L+ + I ++ + VNV Sbjct: 66 DVGDAEAWDVVVAKALDTFGKVDVLVNNAGLIQFAPLEEMPIEMFDRVTRVNVRGPWLG- 124 Query: 362 LKAIEIMGKHSGGKGGTVINVSSV 433 KAI K +G GG +IN+SS+ Sbjct: 125 CKAILPALKAAG--GGAIINMSSM 146 >UniRef50_Q0FWE6 Cluster: Putative oxidoreductase; n=1; Roseovarius sp. HTCC2601|Rep: Putative oxidoreductase - Roseovarius sp. HTCC2601 Length = 257 Score = 61.7 bits (143), Expect = 8e-09 Identities = 40/145 (27%), Positives = 74/145 (51%), Gaps = 6/145 (4%) Frame = +2 Query: 29 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVT 208 + ITGAA G G + R+ EG + + DI + G + + G + + DV Sbjct: 1 MALITGAANGQGAAEARLFAAEGAA-VVVTDIDDANGAEVVAGIEQA-GGRAAYLHHDVG 58 Query: 209 DEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITSTLKA 370 E + + + GG++V++NNA ++ S +G +++A+++N+T + A Sbjct: 59 SEPDWTAAIALAQERFGGLNVLVNNAGIVPRSTIDETALGAWQRALDINLTGPMLGMKLA 118 Query: 371 IEIMGKHSGGKGGTVINVSSVAALT 445 ++ + SG GG+++NVSS A LT Sbjct: 119 APVI-RDSG--GGSIVNVSSAAGLT 140 >UniRef50_A7A2R8 Cluster: Putative uncharacterized protein; n=1; Bifidobacterium adolescentis L2-32|Rep: Putative uncharacterized protein - Bifidobacterium adolescentis L2-32 Length = 330 Score = 61.7 bits (143), Expect = 8e-09 Identities = 43/147 (29%), Positives = 78/147 (53%), Gaps = 6/147 (4%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 196 W + +TGA GIG +V ++L +GVK +A+ DI E ++ V+L + G + Sbjct: 84 WNGQRALVTGAGQGIGRAVAQLLASKGVK-VAVNDIVPERAEN-TVKLIADAGGEAFAAI 141 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAA-LMNDSIG-----IYKKAIEVNVTALITS 358 D+ D + + + GGID+++N A ++ DS+ + + + VN+TA + Sbjct: 142 GDIADPTVVEDLFRQLDERFGGIDILVNVAGIIIKDSLDDTDLERWNRILAVNLTADFLT 201 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVAA 439 +A++ M K G+ ++NVSS+AA Sbjct: 202 IKQAVKRMRKQHYGR---IVNVSSIAA 225 >UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like protein; n=1; Reinekea sp. MED297|Rep: Short-chain alcohol dehydrogenase-like protein - Reinekea sp. MED297 Length = 672 Score = 61.7 bits (143), Expect = 8e-09 Identities = 44/150 (29%), Positives = 80/150 (53%), Gaps = 8/150 (5%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KVV ITG ++GIG++ L G I AE+ ++ +++ S G +++D+ Sbjct: 385 KVVLITGGSSGIGKATAMRLSKAGATVIICARDAEKLRRA-HLDIESTGGTVVS-HQADI 442 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNA------ALMN--DSIGIYKKAIEVNVTALITST 361 T + + + +E G+D++INNA ++M D + +++ IE+N A + T Sbjct: 443 TQPDDVDRLFGMIEREFAGLDILINNAGHSIRRSVMQSLDRLHDFQRTIELNYLASVAIT 502 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAALTQS 451 LKA+ +M + + G VIN+SS+ L+ S Sbjct: 503 LKALPMMDRR---REGHVINISSIGVLSNS 529 >UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Verminephrobacter eiseniae EF01-2|Rep: Short-chain dehydrogenase/reductase SDR - Verminephrobacter eiseniae (strain EF01-2) Length = 261 Score = 61.7 bits (143), Expect = 8e-09 Identities = 38/142 (26%), Positives = 75/142 (52%), Gaps = 7/142 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K ITGAA GIG ++ + + EG H+ + DI++ G+ +L + G+ + DV Sbjct: 7 KTAVITGAADGIGHAIAQAMAREGA-HVFLSDISDAQGERCAAQLRAA-GHLADYLHCDV 64 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 364 + +++ V++ G +DV++NNAA+ + + +++ IE+N+T++ Sbjct: 65 AKADDIARLVDTAVRQTGHLDVMVNNAAIAIGGMPVHEMTDEQWQRLIEINLTSVFRGCK 124 Query: 365 KAIEIMGKHSGGKGGTVINVSS 430 A+ M K G++IN++S Sbjct: 125 CALPHM---IAQKSGSIINMAS 143 >UniRef50_A0KYX3 Cluster: Short-chain dehydrogenase/reductase SDR; n=49; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Shewanella sp. (strain ANA-3) Length = 252 Score = 61.7 bits (143), Expect = 8e-09 Identities = 45/154 (29%), Positives = 80/154 (51%), Gaps = 15/154 (9%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 KDKVV ITG A G+G ++ G K +A++D+ +E + +L S + + Y Sbjct: 4 KDKVVVITGGAGGLGLAMAHNFAQAGAK-LALIDVDQEKLERACADLGS--ATEVQGYAL 60 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVT---------ALI 352 D+TDEE + ++++ G I+V++NNA ++ D G+ KA + VT ++I Sbjct: 61 DITDEEDVVAGFAYILEDFGKINVLVNNAGILRD--GMLVKAKDGKVTDRMSFDQFQSVI 118 Query: 353 TSTLKAIEIMGKHS------GGKGGTVINVSSVA 436 L + G+ + G+ G ++N+SS+A Sbjct: 119 NVNLTGTFLCGREAAAAMIESGQAGVIVNISSLA 152 >UniRef50_Q9LW35 Cluster: Alcohol dehydrogenase-like protein; n=6; rosids|Rep: Alcohol dehydrogenase-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 300 Score = 61.7 bits (143), Expect = 8e-09 Identities = 34/95 (35%), Positives = 53/95 (55%) Frame = +2 Query: 8 SHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK 187 S + + KV ITG A+GIG++ + +G + + I+DI EEAG + EL G+ Sbjct: 33 SRKLEGKVAVITGGASGIGKATAEEFVSQGAQ-VIIVDIDEEAGHMVATEL----GSAAH 87 Query: 188 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL 292 F R DVT+EE + V G +DV++N+A + Sbjct: 88 FLRCDVTEEEQIAKAVETAVTRHGKLDVMLNSAGI 122 >UniRef50_A5UJ48 Cluster: Short chain dehydrogenase; n=1; Methanobrevibacter smithii ATCC 35061|Rep: Short chain dehydrogenase - Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) Length = 269 Score = 61.7 bits (143), Expect = 8e-09 Identities = 39/148 (26%), Positives = 80/148 (54%), Gaps = 8/148 (5%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 KDK+ +TG+ +GIG + ++ EG K + I EE G+++ V+ +K G ++ ++ Sbjct: 7 KDKIAIVTGSTSGIGIGIAKLYAAEGAK-VVICGRREEKGQAV-VDNITKEGGESSYHFF 64 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAA--LMND------SIGIYKKAIEVNVTALIT 355 D+T+ +++ ++ G ID+++NNAA + D +I ++ E ++ Sbjct: 65 DITNTNSIEKLIDDTAEKYGKIDILVNNAANVALKDGNIDELTIDMWDAIFESDLRGTFY 124 Query: 356 STLKAIEIMGKHSGGKGGTVINVSSVAA 439 +T I + K+ GG++IN+ S+A+ Sbjct: 125 ATKCVIPYLQKNE--NGGSIINIGSMAS 150 >UniRef50_Q9KQH7 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=225; cellular organisms|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Vibrio cholerae Length = 244 Score = 61.7 bits (143), Expect = 8e-09 Identities = 41/142 (28%), Positives = 72/142 (50%), Gaps = 6/142 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TGA+ GIG+++ +L + G K I E+G ++ G+ K +V Sbjct: 6 KVALVTGASRGIGKAIAELLAERGAKVIGTA--TSESGAQA---ISDYLGDNGKGMALNV 60 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK------AIEVNVTALITSTLK 367 T+ E +L A+ E GG+D+++NNA + D++ + K +E N+T++ + Sbjct: 61 TNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFRLSKA 120 Query: 368 AIEIMGKHSGGKGGTVINVSSV 433 + M K + G +INV SV Sbjct: 121 VLRGMMKK---RQGRIINVGSV 139 >UniRef50_Q89UC3 Cluster: D-beta-hydroxybutyrate dehydrogenase; n=11; Proteobacteria|Rep: D-beta-hydroxybutyrate dehydrogenase - Bradyrhizobium japonicum Length = 249 Score = 61.3 bits (142), Expect = 1e-08 Identities = 40/145 (27%), Positives = 73/145 (50%), Gaps = 4/145 (2%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K V +TGAA+G+G + R+ EG ++A+ D E+ S+ E+ + G K ++ Sbjct: 2 KGLTVLVTGAASGMGRATARVFAAEGA-NVAVTDYDEQGAISVAKEIAAS-GGSAKAWKL 59 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL-MNDSIG--IYKKAIEVNVTALITSTLKA 370 DV D +++ V GG+D+V+NNA + + +I Y+ A + ++T+ + Sbjct: 60 DVADGGEIKRVVHDVAAHFGGLDIVVNNAGISVRVAIDDETYEDAWARGIAVMLTAHPRI 119 Query: 371 IEIMGKH-SGGKGGTVINVSSVAAL 442 I H K ++N++S AL Sbjct: 120 IRAALPHLRKSKSPRIVNIASTEAL 144 >UniRef50_Q3EU48 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Bacillus thuringiensis serovar israelensis ATCC 35646|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Bacillus thuringiensis serovar israelensis ATCC 35646 Length = 252 Score = 61.3 bits (142), Expect = 1e-08 Identities = 38/147 (25%), Positives = 74/147 (50%), Gaps = 6/147 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 ++K + +TG GIG ++V L EG A ++++ ++ EL S Y ++ Y Sbjct: 11 ENKRIIVTGGCKGIGRAIVEKYLQEGAVVAATYYKSKDSSDQMKSELES-YSDRLAIYNM 69 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITST 361 DV+D E ++ + + GID+++NN+ + DS+ + K I+ N+ + Sbjct: 70 DVSDAEQVNKVMEQIQDDLKGIDILVNNSGITQDSLLYSMKNSDWDKVIKTNLYGPFYTC 129 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAAL 442 + M K K G++IN++SV+ + Sbjct: 130 KSVLLNMIKQ---KYGSIINIASVSGI 153 >UniRef50_Q12G63 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=6; Proteobacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 249 Score = 61.3 bits (142), Expect = 1e-08 Identities = 42/140 (30%), Positives = 71/140 (50%), Gaps = 5/140 (3%) Frame = +2 Query: 32 VFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTD 211 V +TGA TGIG + +G ++ + EEAG+SL EL + G K +F ++DV + Sbjct: 6 VLVTGALTGIGRATAIAFAKQGA-NVVVSGRREEAGQSLAAELRT-LGAKAEFIKADVAN 63 Query: 212 EEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKH 391 E ++ V G +D+ INNA ++G + NV A ++ + + KH Sbjct: 64 EAEVRSLVEKAVSLFGQLDIAINNAG-TEGALGPITEQSTENVHATFSTNVLGTLLSMKH 122 Query: 392 S----GGKG-GTVINVSSVA 436 +G G+++N+SS+A Sbjct: 123 EIRAMQAQGHGSIVNLSSIA 142 >UniRef50_A4AA34 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Congregibacter litoralis KT71|Rep: Short-chain dehydrogenase/reductase SDR - Congregibacter litoralis KT71 Length = 259 Score = 61.3 bits (142), Expect = 1e-08 Identities = 43/141 (30%), Positives = 73/141 (51%), Gaps = 5/141 (3%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV ITGAA+GIGE+ R + G + + DI A +L EL + G + + DV Sbjct: 11 KVALITGAASGIGEASARKMAAAGAS-LVLTDINHSAVAALADELGRE-GTQAAALQHDV 68 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 385 T + + V GG+D+++NNA + D+ + +E N ++++ L + + Sbjct: 69 TQPGDWERAVALAVDTFGGLDILVNNAGIAGDNTDLMNLDLE-NWHSVLSVNLDGVFLGL 127 Query: 386 KHSGGK-----GGTVINVSSV 433 ++SG GG+VIN+SS+ Sbjct: 128 RYSGPALERRGGGSVINISSI 148 >UniRef50_Q6NNV7 Cluster: RH03309p; n=4; melanogaster subgroup|Rep: RH03309p - Drosophila melanogaster (Fruit fly) Length = 247 Score = 61.3 bits (142), Expect = 1e-08 Identities = 38/140 (27%), Positives = 72/140 (51%), Gaps = 6/140 (4%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 196 W + V +TGA++GIG ++ R L+ GV +A+ + + L+ EL ++ + + Sbjct: 4 WHNCVAVVTGASSGIGAAITRKLISAGVMVVALARRMDRL-EQLREELPQDRRSRLRIMQ 62 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITS 358 DV+D + +AV + G +D++INNA L+ S+ ++ ++ NV ++ Sbjct: 63 CDVSDVSSVNAVFDAVQGDLGNVDILINNAGKLSGGQLLTMSVDTVQQMLQTNVMGVVYC 122 Query: 359 TLKAIEIMGKHSGGKGGTVI 418 T +A E M + KG V+ Sbjct: 123 TQRAFESM-RQRQSKGHVVL 141 >UniRef50_Q6IDG8 Cluster: RH36352p; n=2; Drosophila melanogaster|Rep: RH36352p - Drosophila melanogaster (Fruit fly) Length = 237 Score = 61.3 bits (142), Expect = 1e-08 Identities = 38/140 (27%), Positives = 72/140 (51%), Gaps = 6/140 (4%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 196 W + V +TGA++GIG ++ R L+ GV +A+ + + L+ EL ++ + + Sbjct: 10 WHNCVAVVTGASSGIGAAITRKLISAGVMVVALARRMDRL-EQLREELPQDRRSRLRIMQ 68 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALITS 358 DV+D + +AV + G +D++INNA L+ S+ ++ ++ NV ++ Sbjct: 69 CDVSDVSSVNAVFDAVQGDLGNVDILINNAGKLSGGQLLTMSVDTVQQMLQTNVMGVVYC 128 Query: 359 TLKAIEIMGKHSGGKGGTVI 418 T +A E M + KG V+ Sbjct: 129 TQRAFESM-RQRQSKGHVVL 147 >UniRef50_A7EQI6 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 249 Score = 61.3 bits (142), Expect = 1e-08 Identities = 42/147 (28%), Positives = 75/147 (51%), Gaps = 7/147 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K+KV +TG +G GE++ R EG K + I DI G+ + + + + F + Sbjct: 15 KNKVAIVTGGGSGFGEAIARRFAGEGCK-VTIADIDAVGGERVA----NVHPHSMLFVKM 69 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM---NDSIGI----YKKAIEVNVTALITS 358 DVT+EE + +L + + G +DV +NNA ++ + + K VNV ++ + Sbjct: 70 DVTNEEDWERVLETTLAKWGRVDVCVNNAGTSYRNKPTLDVIEDEFDKVFNVNVKSIFYA 129 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVAA 439 T I + G+GG++IN++S+ A Sbjct: 130 TRHFIP--NVINQGEGGSMINIASIGA 154 >UniRef50_Q89P10 Cluster: Oxidoreductase; n=1; Bradyrhizobium japonicum|Rep: Oxidoreductase - Bradyrhizobium japonicum Length = 248 Score = 60.9 bits (141), Expect = 1e-08 Identities = 44/143 (30%), Positives = 73/143 (51%), Gaps = 5/143 (3%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV ITGA +GIG ++ R+ EG K + + D+A E G +L L + G+ F DV Sbjct: 7 KVAVITGAGSGIGAAIARLFAVEGAK-VLLGDLA-EGGAALAAGLAAD-GHAAGFQHVDV 63 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 385 TDE ++ A V G +D+++ NA + I++ + V+ +I L + I Sbjct: 64 TDEASVAELMQAAVTLFGRLDILVANAGIPERKSPIHELDL-VDWRRVIDVDLTGVAICN 122 Query: 386 KHSGG-----KGGTVINVSSVAA 439 K + G GG ++N++S+ A Sbjct: 123 KFAAGIMRATGGGAIVNMASILA 145 >UniRef50_Q3IE88 Cluster: 3-ketoacyl-acyl carrier protein reductase; n=3; Proteobacteria|Rep: 3-ketoacyl-acyl carrier protein reductase - Pseudoalteromonas haloplanktis (strain TAC 125) Length = 247 Score = 60.9 bits (141), Expect = 1e-08 Identities = 44/148 (29%), Positives = 72/148 (48%), Gaps = 6/148 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 +D+VV +TGA GIG+S+V G ++A +DI + + ELN+ + Sbjct: 4 QDQVVLVTGAGQGIGQSIVSYFATAGA-NVAAVDINADTLNASVNELNANVAGNIVAITA 62 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNA------ALMNDSIGIYKKAIEVNVTALITST 361 ++ + + AVV++ G +D +IN A A ++ + K I VN+T Sbjct: 63 NIAKSDSVRDAIAAVVEKFGRLDAIINVAGVGSIDAFVDTPDEHWDKVIAVNLTGTFLCC 122 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAALT 445 +A ++M G +INVSS AALT Sbjct: 123 REAAKVMQAQG---SGCIINVSSTAALT 147 >UniRef50_Q1V2H3 Cluster: Short chain dehydrogenase; n=2; Candidatus Pelagibacter ubique|Rep: Short chain dehydrogenase - Candidatus Pelagibacter ubique HTCC1002 Length = 253 Score = 60.9 bits (141), Expect = 1e-08 Identities = 40/144 (27%), Positives = 72/144 (50%), Gaps = 5/144 (3%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K+K VF+TG +GIG S+V ++G + +DI E+A L +E +K + F + Sbjct: 9 KNKRVFVTGGGSGIGASIVEHFCEQG-SEVYFIDINEKASNKLVLECKNKNFSVPTFIKC 67 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLK---- 367 D+ + + ++ ++ G IDV++NNAA ND + E + L+ Sbjct: 68 DLLNIKDLQNTISKIIDNNGAIDVLVNNAA--NDERHSIDEVTEEFWNERMNINLRHYFF 125 Query: 368 AIEIMGKHS-GGKGGTVINVSSVA 436 ++ + K K G++IN+ SV+ Sbjct: 126 TVQSVKKAMIANKSGSIINIGSVS 149 >UniRef50_Q1ARQ7 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Rubrobacter xylanophilus DSM 9941|Rep: Short-chain dehydrogenase/reductase SDR - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 251 Score = 60.9 bits (141), Expect = 1e-08 Identities = 44/145 (30%), Positives = 73/145 (50%), Gaps = 6/145 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K +TGA +GIG ++ EG + +A+ D+ E A + + E+ G R+DV Sbjct: 7 KRTIVTGAGSGIGRAIALRFAAEGAR-VALADVDEGAARKVAAEI----GEGCLVQRTDV 61 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 367 T E G++ + GG++V++NNA + S +++ + VN+ Sbjct: 62 TVAEEVEGLVRLATERWGGLEVMVNNAGVGVAATAPQTSEEDFERVLAVNLRGTFLGMKY 121 Query: 368 AIEIMGKHSGGKGGTVINVSSVAAL 442 AI + + SG GG VIN+SS+AAL Sbjct: 122 AIPAI-RDSG--GGAVINMSSIAAL 143 >UniRef50_Q182R6 Cluster: Probable short chain dehydrogenase precursor; n=2; Clostridium difficile|Rep: Probable short chain dehydrogenase precursor - Clostridium difficile (strain 630) Length = 245 Score = 60.9 bits (141), Expect = 1e-08 Identities = 38/144 (26%), Positives = 72/144 (50%), Gaps = 6/144 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K K V ITG A GIG+++ + EG + + +E K L LN K K +++ Sbjct: 2 KKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKELYTILNEK-NFSVKLFKA 60 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITST 361 ++++ E +++ ++E GG+DV++NNA + D + + + +N+ + Sbjct: 61 NISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITDEDWDNMMNINLKGSFYCS 120 Query: 362 LKAIEIMGKHSGGKGGTVINVSSV 433 A++ M K G +IN+SS+ Sbjct: 121 QVALKYM---ISEKKGNIINISSI 141 >UniRef50_Q0S7P7 Cluster: Short chain dehydrogenase; n=7; Bacteria|Rep: Short chain dehydrogenase - Rhodococcus sp. (strain RHA1) Length = 260 Score = 60.9 bits (141), Expect = 1e-08 Identities = 43/142 (30%), Positives = 73/142 (51%), Gaps = 6/142 (4%) Frame = +2 Query: 29 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVT 208 +V +TG G+G + R L G +A A G++ VE++ G +F D+ Sbjct: 9 IVLVTGGVRGVGAGISRTFLRAGATVVAC---ARRPGEA-PVEVD---GRAIEFLPCDIR 61 Query: 209 DEEHFLGILNAVVQEQGGIDVVINNA-----ALMND-SIGIYKKAIEVNVTALITSTLKA 370 D E G+++ +V+ G +DV++NNA AL D S + K +E+N+ A + + A Sbjct: 62 DPEQVQGLVDRIVERHGRLDVLVNNAGGAPFALAADASPKFHSKIVELNLLAPLLVSQTA 121 Query: 371 IEIMGKHSGGKGGTVINVSSVA 436 +M K GG ++N+SSV+ Sbjct: 122 NAVMQKQD--SGGAIVNISSVS 141 >UniRef50_A0JVX6 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Arthrobacter sp. FB24|Rep: Short-chain dehydrogenase/reductase SDR - Arthrobacter sp. (strain FB24) Length = 279 Score = 60.9 bits (141), Expect = 1e-08 Identities = 42/149 (28%), Positives = 73/149 (48%), Gaps = 7/149 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV I+GAA+GIGE+V RI K + ++DI EE + + + +DV Sbjct: 16 KVAIISGAASGIGEAVARIFAANESK-VLLVDIDEERLEKVTASIRGYGRGDVHSILADV 74 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 364 TDE+ + + G +D+++N+A +++ ++ + K + N+TA+ Sbjct: 75 TDEQSVIDLFAWAKTNWGSVDLIVNSAGRDSLAPPVVDVTLDEWNKTMTPNLTAVFLMCR 134 Query: 365 KAIEIMGKHSGGKGGTVINVSSVAALTQS 451 +A IM K GG +IN+ S +A S Sbjct: 135 EAFRIMEKQE--NGGRIINMGSSSARVAS 161 >UniRef50_A6XGT9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reductase; n=1; Polytomella parva|Rep: 3-oxoacyl-(Acyl-carrier-protein) reductase - Polytomella parva Length = 223 Score = 60.9 bits (141), Expect = 1e-08 Identities = 38/141 (26%), Positives = 74/141 (52%), Gaps = 6/141 (4%) Frame = +2 Query: 29 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVT 208 V +TG++ GIG+++ L +G K + + +A + ++ + G ++D++ Sbjct: 40 VCIVTGSSRGIGKAIALSLGAQGSKVVVNYSASSKAADEVAQKI-IEIGGDAIVVKADMS 98 Query: 209 DEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLKA 370 E + A + G +DVV+NNA + DS+ + + + I VN++++ ST A Sbjct: 99 KREEIEALYKATTAKWGKLDVVVNNAGITRDSLMMRMKPEQWNEVINVNLSSVFFSTQLA 158 Query: 371 IEIMGKHSGGKGGTVINVSSV 433 +IMGK K G ++N++SV Sbjct: 159 TKIMGKQ---KRGRIVNITSV 176 >UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular organisms|Rep: Oxidoreductase - Halobacterium salinarium (Halobacterium halobium) Length = 260 Score = 60.9 bits (141), Expect = 1e-08 Identities = 44/148 (29%), Positives = 71/148 (47%), Gaps = 6/148 (4%) Frame = +2 Query: 11 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF 190 HE V +TGA++GIGE+ L EG + A+E +L + G+ Sbjct: 16 HELAGDVAIVTGASSGIGEATAEALAAEGAHVVLAARRADELA-ALADRIEDTDGDAL-V 73 Query: 191 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALI 352 +D+TD++ +++ V E G ID+++NNA +M ++ +EVN+ L+ Sbjct: 74 VPTDITDDDAIDDLVSETVDEYGRIDILVNNAGVMLLEPLERADRSNLRQMVEVNLLGLM 133 Query: 353 TSTLKAIEIMGKHSGGKGGTVINVSSVA 436 T + IM G V+NVSSVA Sbjct: 134 NLTHAVVPIMQDQDAGH---VVNVSSVA 158 >UniRef50_P50203 Cluster: Acetoacetyl-CoA reductase; n=34; Proteobacteria|Rep: Acetoacetyl-CoA reductase - Acinetobacter sp. (strain RA3849) Length = 248 Score = 60.9 bits (141), Expect = 1e-08 Identities = 40/147 (27%), Positives = 68/147 (46%), Gaps = 6/147 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 + KV +TGA GIG + R L+ G K IA + EE + ++ + +F + Sbjct: 3 EQKVALVTGALGGIGSEICRQLVTAGYKIIATVVPREEDREKQWLQSEGFQDSDVRFVLT 62 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITST 361 D+ + E + + +G +DV++NNA + D S + + I+ N+ L T T Sbjct: 63 DLNNHEAATAAIQEAIAAEGRVDVLVNNAGITRDATFKKMSYEQWSQVIDTNLKTLFTVT 122 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAAL 442 + K K G ++N+SSV L Sbjct: 123 Q---PVFNKMLEQKSGRIVNISSVNGL 146 >UniRef50_A7MR86 Cluster: Putative uncharacterized protein; n=1; Enterobacter sakazakii ATCC BAA-894|Rep: Putative uncharacterized protein - Enterobacter sakazakii ATCC BAA-894 Length = 265 Score = 60.5 bits (140), Expect = 2e-08 Identities = 38/144 (26%), Positives = 69/144 (47%), Gaps = 7/144 (4%) Frame = +2 Query: 29 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVT 208 V ITGA+ GIG + +L +G +A+ + A VE G + ++D++ Sbjct: 21 VALITGASRGIGRATALLLGAQGYT-VAVNYLHNAAAAQEVVERIVASGGRAFAIQADIS 79 Query: 209 DEEHFLGILNAVVQEQGGIDVVINNAALM-------NDSIGIYKKAIEVNVTALITSTLK 367 DE + + + ++ + ++NNA ++ N + K + NVT + Sbjct: 80 DEPQVMAMFRTLDEQDEPLGALVNNAGVLFTQCMTENLTAERINKVLATNVTGYFLCCRE 139 Query: 368 AIEIMGKHSGGKGGTVINVSSVAA 439 A++ M H GG+GG ++NVSS A+ Sbjct: 140 AVKRMAHHHGGQGGAIVNVSSAAS 163 >UniRef50_A6VSM3 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Marinomonas sp. MWYL1|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MWYL1 Length = 254 Score = 60.5 bits (140), Expect = 2e-08 Identities = 33/89 (37%), Positives = 51/89 (57%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 KDKVVFITG +GIGE +V + +G + +A +DI + + +L +L ++ F + Sbjct: 12 KDKVVFITGGGSGIGEFLVHHFMKQGAR-VAYIDIDDASSTTLNQKLADEFKVTPWFRKV 70 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNA 286 DV D ++ QE G +DV+INNA Sbjct: 71 DVRDIAALQSAIDDAAQELGHLDVLINNA 99 >UniRef50_A1UAJ6 Cluster: Acetoin reductases; n=18; Bacteria|Rep: Acetoin reductases - Mycobacterium sp. (strain KMS) Length = 285 Score = 60.5 bits (140), Expect = 2e-08 Identities = 43/146 (29%), Positives = 72/146 (49%), Gaps = 9/146 (6%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TGA GIG + L +G IA++D++E E+ S+ G+KT + +DV Sbjct: 27 KVALVTGAGRGIGRGIAVELARQGAD-IALVDVSEAGLPDAAAEI-SEIGSKTTTFVADV 84 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNA--ALMNDSIGIYKKAI----EVNVTAL---ITS 358 D + ++ GG DV++NNA AL+ + + + +NV + I + Sbjct: 85 RDRDAVFAAVDHAAAALGGFDVMVNNAGIALVGPIAEVTAEDLARLWAINVDGVLWGIQA 144 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVA 436 + +G H+ GK +IN SS+A Sbjct: 145 AAAKFKELGNHAEGKVSKIINASSIA 170 >UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 253 Score = 60.5 bits (140), Expect = 2e-08 Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 5/148 (3%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 193 ++ KVV ITG ATGIG + +G + + + D+ + A ++ V L + G F Sbjct: 6 DFTGKVVLITGGATGIGRATALAFAQQGAR-VVVGDVDDRAAET--VRLIEESGGTALFV 62 Query: 194 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 373 R+DVT ++ V GG+ V NNA ++ + G + E + I LK + Sbjct: 63 RTDVTSAADVQQLVRTTVDTYGGLHVAFNNAGILPPT-GPLAEQSEDDFDRTIAVDLKGV 121 Query: 374 EIMGKH-----SGGKGGTVINVSSVAAL 442 + K+ + GG++IN +SVA + Sbjct: 122 FLALKYEIEHMAAAGGGSIINTASVAGV 149 >UniRef50_Q8TUG0 Cluster: Gluconate 5-dehydrogenase; n=7; cellular organisms|Rep: Gluconate 5-dehydrogenase - Methanosarcina acetivorans Length = 255 Score = 60.5 bits (140), Expect = 2e-08 Identities = 42/141 (29%), Positives = 69/141 (48%), Gaps = 5/141 (3%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TGA++G+G R L ++G +IAI+ EE K +Q E+ K G ++Y DV Sbjct: 10 KVAIVTGASSGLGVEFARALANQGA-NIAIIARREEKLKEVQKEIE-KLGVTCRYYLCDV 67 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 385 E + VV++ G ID+++NNA L + K + +I + L + Sbjct: 68 MKTEQIKNAVEQVVKDFGRIDILVNNAGL--GLVDAADKTTDEMWHNMIDTNLNGVYFFA 125 Query: 386 KHSG-----GKGGTVINVSSV 433 + G K G +IN+ S+ Sbjct: 126 REVGKIMLRQKHGRIINIGSI 146 >UniRef50_A7I951 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Candidatus Methanoregula boonei 6A8|Rep: Short-chain dehydrogenase/reductase SDR - Methanoregula boonei (strain 6A8) Length = 253 Score = 60.5 bits (140), Expect = 2e-08 Identities = 40/145 (27%), Positives = 72/145 (49%), Gaps = 6/145 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV+ +TGA+ GIG + + + I + +SL E+ + G+ R+DV Sbjct: 12 KVILVTGASRGIGRATAFLAAKNHAQVIVNYQKHADQAESLVSEITA-LGHSAMAIRADV 70 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITSTLK 367 T EE + + ++ G +D+++NNA +M ++ I Y+ ++VN T Sbjct: 71 TCEEEVKEMFRQIREQYGRLDILVNNAGIMKNNLLMMTKIQEYQDVMDVNCKGTFLCTQH 130 Query: 368 AIEIMGKHSGGKGGTVINVSSVAAL 442 A +IM + K GT+IN++SV + Sbjct: 131 AAKIMVRQ---KAGTIINLASVVGV 152 >UniRef50_P07914 Cluster: Bile acid 7-dehydroxylase 1/3; n=3; Clostridium|Rep: Bile acid 7-dehydroxylase 1/3 - Eubacterium sp. (strain VPI 12708) Length = 249 Score = 60.5 bits (140), Expect = 2e-08 Identities = 37/148 (25%), Positives = 70/148 (47%), Gaps = 7/148 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF-YR 196 +DK+ ITG GIG + ++ ++ G K ++I +E + +L Y + + Sbjct: 5 QDKITIITGGTRGIGFAAAKLFIENGAK-VSIFGETQEEVDTALAQLKELYPEEEVLGFA 63 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITS 358 D+T + + + V Q+ G +DV+INNA + +S+ +K +++NV + Sbjct: 64 PDLTSRDAVMAAVGTVAQKYGRLDVMINNAGITMNSVFSRVSEEDFKNIMDINVNGVFNG 123 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVAAL 442 A + M K G +IN +SV + Sbjct: 124 AWSAYQCM---KDAKQGVIINTASVTGI 148 >UniRef50_UPI00015B5DCD Cluster: PREDICTED: similar to oxidoreductase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to oxidoreductase - Nasonia vitripennis Length = 254 Score = 60.1 bits (139), Expect = 2e-08 Identities = 40/148 (27%), Positives = 76/148 (51%), Gaps = 8/148 (5%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY- 193 W+ KV +TGA++GIG VV +L+ +K ++ +A Q+ + FY Sbjct: 4 WRGKVAVVTGASSGIGAYVVELLVRADMK---VVGLARRVEVLQQMASRMAKHHPGSFYP 60 Query: 194 -RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALI 352 + D+ EE L ++ G ++V++NNA +++ S ++K +++NV A+ Sbjct: 61 VKCDLQKEEDILEAFKYTEEKVGPVNVLVNNAGFLVSERIIDSSTENFRKILDINVLAVA 120 Query: 353 TSTLKAIEIMGKHSGGKGGTVINVSSVA 436 +A ++M KH G ++N++SVA Sbjct: 121 ICIREATKLMRKHK--VHGHIVNINSVA 146 >UniRef50_UPI00004996DD Cluster: 3-oxoacyl-(acyl-carrier protein) reductase; n=1; Entamoeba histolytica HM-1:IMSS|Rep: 3-oxoacyl-(acyl-carrier protein) reductase - Entamoeba histolytica HM-1:IMSS Length = 265 Score = 60.1 bits (139), Expect = 2e-08 Identities = 37/142 (26%), Positives = 76/142 (53%), Gaps = 4/142 (2%) Frame = +2 Query: 17 WKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYR 196 ++ KV ITG +GIGE++VR L ++ ++ + +E G+S+ ELN+K+ + F Sbjct: 3 FEGKVALITGGTSGIGEAIVRQLTEQKC-NVIFIGRRKELGESISHELNNKHFGQIDFIP 61 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIE 376 DVT+ + + +++ V ++ +D+++NNA ++ + + E + + +K++ Sbjct: 62 FDVTNFKEYDSLVHIVQEKYNRLDLLVNNAGIV--TYDTCDELTEETFDLIYQTNVKSVW 119 Query: 377 IMGKHSGG----KGGTVINVSS 430 M KH G V+N+ S Sbjct: 120 QMTKHFHNLLEQSYGAVVNIGS 141 >UniRef50_Q6LH36 Cluster: Hypothetical oxidoreductase, short-chain dehydrogenase/reductase family; n=1; Photobacterium profundum|Rep: Hypothetical oxidoreductase, short-chain dehydrogenase/reductase family - Photobacterium profundum (Photobacterium sp. (strain SS9)) Length = 255 Score = 60.1 bits (139), Expect = 2e-08 Identities = 40/146 (27%), Positives = 69/146 (47%), Gaps = 7/146 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV I+G +GIGE+ R+ +G + ++ E G+ L ELN++Y T F ++D+ Sbjct: 10 KVALISGITSGIGEATARLFSQQGAS-LVLVARNENKGQMLAEELNAQY--PTLFIKADI 66 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITSTL 364 T + + E GGID NNA + S I+ + I N+ Sbjct: 67 TQANQVDQVFEQTMAEFGGIDCAFNNAGIDGSKQPISETSDEIWNQIINTNLNGTWNMLN 126 Query: 365 KAIEIMGKHSGGKGGTVINVSSVAAL 442 + + IM K GT++N++S+ ++ Sbjct: 127 RQLSIMSKQG---HGTIVNMASICSV 149 >UniRef50_Q67M07 Cluster: Short-chain dehydrogenase; n=2; Bacteria|Rep: Short-chain dehydrogenase - Symbiobacterium thermophilum Length = 254 Score = 60.1 bits (139), Expect = 2e-08 Identities = 45/145 (31%), Positives = 70/145 (48%), Gaps = 6/145 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV ITGAA G+G + + EG + + I D+ EE G++ Q G F R+DV Sbjct: 7 KVAIITGAAMGMGAATAELFAREGAR-VVIADLNEELGRA-QARKIQDAGGAAAFVRADV 64 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 385 + ++ V G +DV +NNAA D+ + E A+I LK + + Sbjct: 65 SRAGDVEAMVQFAVDTFGRLDVAVNNAAHSPDTRPL-ADLDEAVWDAVIGVDLKGVALCL 123 Query: 386 KH------SGGKGGTVINVSSVAAL 442 K+ G GG++IN+SSV+ + Sbjct: 124 KYELRQMLKQGGGGSIINISSVSGI 148 >UniRef50_Q65F37 Cluster: Putative uncharacterized protein; n=1; Bacillus licheniformis ATCC 14580|Rep: Putative uncharacterized protein - Bacillus licheniformis (strain DSM 13 / ATCC 14580) Length = 248 Score = 60.1 bits (139), Expect = 2e-08 Identities = 43/153 (28%), Positives = 75/153 (49%), Gaps = 6/153 (3%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 193 E+ + ITGA+ GIG ++ +L D+G ++ I EE KSL +LN++ + Sbjct: 2 EFNQQTAIITGASRGIGRAIAELLADKGA-NVVINGTNEELLKSLCTQLNTE-RKCASYV 59 Query: 194 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALIT 355 D + E ++ Q G ID+++NNA + ++ S+ +K+ I++N+T Sbjct: 60 AGDASLPETASLLIAEAKQRFGRIDILVNNAGVNLRKTTVDTSLEEWKRVIDLNLTGTFL 119 Query: 356 STLKAIEIMGKHSGGKGGTVINVSSVAALTQSH 454 I M GGK ++N+SS + T H Sbjct: 120 MCQAVIPEMITQGGGK---IVNMSSTTSKTPHH 149 >UniRef50_Q5NM60 Cluster: Short-chain alcohol dehydrogenase; n=14; cellular organisms|Rep: Short-chain alcohol dehydrogenase - Zymomonas mobilis Length = 248 Score = 60.1 bits (139), Expect = 2e-08 Identities = 44/145 (30%), Positives = 76/145 (52%), Gaps = 6/145 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 ++K+V ITGA++G+G R L D G + + EE +L + +K G + ++ Sbjct: 6 RNKIVVITGASSGLGAETARHLSDLGAT-VVLGARREERIATLANSIVAK-GGQALAIKT 63 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDS------IGIYKKAIEVNVTALITST 361 DVTD E +++ V+ G +DV++NNA +M S + ++ ++VN+ ++ Sbjct: 64 DVTDRESVKNLVDTAVKTYGRVDVLLNNAGVMPLSPLEKLRVDEWELMVDVNIKGVLYGI 123 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVA 436 A+ M K G +INVSSVA Sbjct: 124 AAALPHM---KSQKFGHIINVSSVA 145 >UniRef50_Q4FMR3 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=2; Candidatus Pelagibacter ubique|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Pelagibacter ubique Length = 245 Score = 60.1 bits (139), Expect = 2e-08 Identities = 44/149 (29%), Positives = 73/149 (48%), Gaps = 7/149 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 KDK + +TGA+ GIG S+V L G +A E+ EL K+ N K + Sbjct: 5 KDKNIIVTGASGGIGNSIVEKLNQNGANILATGTRIEKL-----EELKEKF-NNIKILKF 58 Query: 200 DVTDEEHFLGILNAVVQEQGG-IDVVINNAALMNDSIGI------YKKAIEVNVTALITS 358 D++ + + +E GG +D ++NNA + D++ I + K I +N+T+ Sbjct: 59 DISQHDKIEEFIENATKELGGSLDCIVNNAGITKDNLTIRMSLEEWSKVININLTSTFLM 118 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVAALT 445 +I+ M K+ GK +IN++SV T Sbjct: 119 CKYSIKKMLKNKSGK---IINITSVVGHT 144 >UniRef50_Q13E96 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Rhodopseudomonas palustris BisB5|Rep: Short-chain dehydrogenase/reductase SDR - Rhodopseudomonas palustris (strain BisB5) Length = 263 Score = 60.1 bits (139), Expect = 2e-08 Identities = 41/146 (28%), Positives = 68/146 (46%), Gaps = 7/146 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 +VV +TG A+GIG + +G + + DI + G VE + G++ ++ R+DV Sbjct: 21 RVVLVTGGASGIGRAAALAWARQGCS-VLVADIDDRGGAET-VEAIERLGSRARYQRNDV 78 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 364 TDE ++ V G +DV NNA + S I ++ I VN+ + S Sbjct: 79 TDERECASLVEQAVLHFGRLDVAFNNAGITGPSAYIANYPGADWRHVINVNLLGIFNSMQ 138 Query: 365 KAIEIMGKHSGGKGGTVINVSSVAAL 442 + + S G G ++N +SV L Sbjct: 139 PQLRLF--ESQG-AGVIVNTASVIGL 161 >UniRef50_O32291 Cluster: YxnA protein; n=4; Bacteria|Rep: YxnA protein - Bacillus subtilis Length = 356 Score = 60.1 bits (139), Expect = 2e-08 Identities = 48/146 (32%), Positives = 73/146 (50%), Gaps = 8/146 (5%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 KD+V+ ITGA++GIG R+ ++G K +A EEA K L EL K G+ + ++ Sbjct: 30 KDQVIVITGASSGIGLVTARMAAEKGAKVVAAAR-NEEALKELTDELKEK-GHDAIWVKA 87 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITST 361 DV EE I + G D +NNAA+ M+ ++ K+ + N + T Sbjct: 88 DVGKEEDVNRIAETAISTFGRFDTWVNNAAVSTFGHAMDVTVEDMKRMFDTNFWGPVYGT 147 Query: 362 LKAIEIMGKHSGGKG--GTVINVSSV 433 A+ KH G+G G +INV S+ Sbjct: 148 RAAV----KHYTGRGVPGALINVGSL 169 >UniRef50_Q15Q07 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Gammaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Pseudoalteromonas atlantica (strain T6c / BAA-1087) Length = 270 Score = 60.1 bits (139), Expect = 2e-08 Identities = 43/148 (29%), Positives = 74/148 (50%), Gaps = 7/148 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K KV+ ITG ATGIG +V + + + + +D+ EEA +L +L+++ G F Sbjct: 26 KGKVILITGGATGIGAVMVEAFMRQQAR-VLFVDVQEEAAHALCSKLHAELGAAPIFKNL 84 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAA-------LMNDSIGIYKKAIEVNVTALITS 358 D T + ++++ G +DV+INN A L D G ++ + VN+ + + Sbjct: 85 DTTHIDELQAFISSIGHSHGRLDVLINNVANDTRHSPLDIDQQG-WRDCMAVNLDSTFFA 143 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVAAL 442 AI +M + G +IN+SS+ L Sbjct: 144 CQSAIRLM---RDKRTGNIINMSSINVL 168 >UniRef50_A5V1Y0 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Roseiflexus sp. RS-1 Length = 246 Score = 60.1 bits (139), Expect = 2e-08 Identities = 44/146 (30%), Positives = 72/146 (49%), Gaps = 5/146 (3%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K KV +TGA GIG++ EG H+A++DI AG V ++ + ++ Sbjct: 4 KGKVAIVTGAGHGIGKATAIAFAREGA-HVAVVDI-NMAGAEATVAEITRLDGRALAVQA 61 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 379 DV+ ++ V+ G IDV++NNA + D+ + K E A+I LK + + Sbjct: 62 DVSQAASVESMVETVLAWGGRIDVLLNNAGITRDARLV--KMTEQQWDAVINVNLKGVWL 119 Query: 380 MGK----HSGGKG-GTVINVSSVAAL 442 + H +G G++INVSS+ L Sbjct: 120 CARAVAPHMSAQGSGSIINVSSIVGL 145 >UniRef50_A0M3M9 Cluster: Short-chain dehydrogenase/reductase family protein; n=14; Bacteroidetes|Rep: Short-chain dehydrogenase/reductase family protein - Gramella forsetii (strain KT0803) Length = 295 Score = 60.1 bits (139), Expect = 2e-08 Identities = 44/147 (29%), Positives = 71/147 (48%), Gaps = 6/147 (4%) Frame = +2 Query: 14 EWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFY 193 E DK+V ITGA++GIG+S+ L K +E+ S+ F Sbjct: 27 ESSDKIVLITGASSGIGKSIATYLAKRNFKVYGTSRSKKESSDSV-----------FNFV 75 Query: 194 RSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTALIT 355 + DVT+E+ + +N + +++G IDV+INNA + KKA E N + Sbjct: 76 QLDVTNEQSIIAAINEISKKEGRIDVLINNAGVGITGPIEETPESEIKKAFETNYFGPLN 135 Query: 356 STLKAIEIMGKHSGGKGGTVINVSSVA 436 + +M K++ GG +INV+S+A Sbjct: 136 MIKNVLPVMRKNN---GGLIINVTSIA 159 >UniRef50_Q5TWK5 Cluster: ENSANGP00000025423; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000025423 - Anopheles gambiae str. PEST Length = 191 Score = 60.1 bits (139), Expect = 2e-08 Identities = 39/136 (28%), Positives = 68/136 (50%), Gaps = 1/136 (0%) Frame = +2 Query: 38 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDVTDEE 217 + G G+G ++ + LL +GVK + I+D+ E +L S D+++ Sbjct: 10 VFGGCGGMGMAIGQHLLRQGVKKLCIVDVVELTDSNLSCLKESGRDALILCKICDISNRA 69 Query: 218 HFLGILNAVVQEQ-GGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMGKHS 394 +L + E G ID+++N+A ++ + K I T +I S L A+ +M + Sbjct: 70 ALKQLLERDISEALGSIDILVNSAGIVESEVP--DKLIG---TGVINSCLIALNLMSRAK 124 Query: 395 GGKGGTVINVSSVAAL 442 GGKGG ++NV+S A L Sbjct: 125 GGKGGVIVNVASTAGL 140 >UniRef50_P52037 Cluster: Uncharacterized oxidoreductase ygfF; n=23; Proteobacteria|Rep: Uncharacterized oxidoreductase ygfF - Escherichia coli (strain K12) Length = 247 Score = 60.1 bits (139), Expect = 2e-08 Identities = 36/145 (24%), Positives = 71/145 (48%), Gaps = 8/145 (5%) Frame = +2 Query: 29 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQV-ELNSKYGNKTKFYRSDV 205 + +TG + GIG + +L EG + ++ + + +V L ++ G K ++D+ Sbjct: 3 IALVTGGSRGIGRATALLLAQEG--YTVAVNYQQNLHAAQEVMNLITQAGGKAFVLQADI 60 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALM-------NDSIGIYKKAIEVNVTALITSTL 364 +DE + + A+ Q + ++NNA ++ N + + + NVT Sbjct: 61 SDENQVVAMFTAIDQHDEPLAALVNNAGILFTQCTVENLTAERINRVLSTNVTGYFLCCR 120 Query: 365 KAIEIMGKHSGGKGGTVINVSSVAA 439 +A++ M +GG GG ++NVSSVA+ Sbjct: 121 EAVKRMALKNGGSGGAIVNVSSVAS 145 >UniRef50_P00334 Cluster: Alcohol dehydrogenase; n=485; Drosophilidae|Rep: Alcohol dehydrogenase - Drosophila melanogaster (Fruit fly) Length = 256 Score = 60.1 bits (139), Expect = 2e-08 Identities = 41/137 (29%), Positives = 67/137 (48%), Gaps = 2/137 (1%) Frame = +2 Query: 29 VVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVE-LNSKYGNKTKFYRSDV 205 V+F+ G GIG + LL +K++ ILD E +++ +N K FY DV Sbjct: 10 VIFVAGLG-GIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKV--TVTFYPYDV 66 Query: 206 T-DEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM 382 T +L + + +DV+IN A +++D ++ I VN T L+ +T ++ Sbjct: 67 TVPIAETTKLLKTIFAQLKTVDVLINGAGILDDH--QIERTIAVNYTGLVNTTTAILDFW 124 Query: 383 GKHSGGKGGTVINVSSV 433 K GG GG + N+ SV Sbjct: 125 DKRKGGPGGIICNIGSV 141 >UniRef50_Q9S3U5 Cluster: 7-alpha-hydroxysteroid dehydrogenase; n=6; Bacteroides|Rep: 7-alpha-hydroxysteroid dehydrogenase - Bacteroides fragilis Length = 259 Score = 59.7 bits (138), Expect = 3e-08 Identities = 41/154 (26%), Positives = 76/154 (49%), Gaps = 9/154 (5%) Frame = +2 Query: 11 HEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKF 190 + +++K++ ITGAA GIG S R ++ EG K + I D + E EL++ + Sbjct: 2 NRFENKIIIITGAAGGIGASTTRRIVSEGGK-VVIADYSREKADQFAAELSNSGADVRPV 60 Query: 191 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMND---------SIGIYKKAIEVNVT 343 Y S T+ + ++ ++E G IDV++NN N + + +A +N++ Sbjct: 61 YFS-ATELKSCKELITFTMKEYGQIDVLVNNVGGTNPRRDTNIETLDMDYFDEAFHLNLS 119 Query: 344 ALITSTLKAIEIMGKHSGGKGGTVINVSSVAALT 445 + + I IM GG ++NV+S++ +T Sbjct: 120 CTMYLSQLVIPIMSTQG---GGNIVNVASISGIT 150 >UniRef50_Q13KN3 Cluster: Putative short-chain type dehydrogenase; n=1; Burkholderia xenovorans LB400|Rep: Putative short-chain type dehydrogenase - Burkholderia xenovorans (strain LB400) Length = 252 Score = 59.7 bits (138), Expect = 3e-08 Identities = 48/143 (33%), Positives = 69/143 (48%), Gaps = 6/143 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K + ITGA IG+ R + EG + + I DIAEEAG+++ EL G F + DV Sbjct: 8 KRIIITGAIGNIGKEAARGFIAEGAR-VVIGDIAEEAGRAVAAEL----GAAAHFVQVDV 62 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 385 T E ++ V+ GG+D + NA L G + N AL +A Sbjct: 63 TSEASVANLIARGVEWLGGLDALAQNAGLQRS--GAIAGFEQANWDALFAVNARAHFFGA 120 Query: 386 KHS------GGKGGTVINVSSVA 436 KH+ GK G++IN+SS+A Sbjct: 121 KHAIPHLQRSGK-GSIINMSSLA 142 >UniRef50_Q029B5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR - Solibacter usitatus (strain Ellin6076) Length = 252 Score = 59.7 bits (138), Expect = 3e-08 Identities = 42/141 (29%), Positives = 67/141 (47%), Gaps = 3/141 (2%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 KD+V ITG ATGIGE+V R+ +G H+ ILD E S+ + + G Sbjct: 8 KDRVALITGGATGIGEAVARLFACQGA-HVHILDRDVEGCNSVAQSICAD-GGSAVASGG 65 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAAL--MNDSIGIYKKAIEVNVTALITSTLKAI 373 DV + Q G ID++INNA + +G+ ++ + + S + + Sbjct: 66 DVCSTNDVQRWVEGAAQRSGRIDILINNAGIYPRQQFLGMSEQQWDAMQDTNLKSMFRTL 125 Query: 374 EIMGKHSGGKG-GTVINVSSV 433 + + H +G G V+N+SSV Sbjct: 126 QAVLPHMVKRGSGKVVNISSV 146 >UniRef50_Q026E7 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Solibacter usitatus Ellin6076|Rep: Short-chain dehydrogenase/reductase SDR - Solibacter usitatus (strain Ellin6076) Length = 251 Score = 59.7 bits (138), Expect = 3e-08 Identities = 42/148 (28%), Positives = 75/148 (50%), Gaps = 6/148 (4%) Frame = +2 Query: 8 SHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK 187 S + KD+V ITGA+ G+G+++ L EG + IA++ E + EL + G Sbjct: 2 SGKLKDRVAVITGASKGLGKAMAMALAAEGTR-IALVSRDEARLNEVAAELIAA-GGDAA 59 Query: 188 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAA------LMNDSIGIYKKAIEVNVTAL 349 +R+DVT EE A++ G +D++INNA ++ ++ + + ++ NVTA Sbjct: 60 IFRADVTSEEQVRQAERAILATYGKVDILINNAGVNVRKPVVEFTVEEWHRVMDTNVTAA 119 Query: 350 ITSTLKAIEIMGKHSGGKGGTVINVSSV 433 + M SG G ++N++S+ Sbjct: 120 FLMCRSFVPAM---SGRGYGRILNMTSI 144 >UniRef50_O33454 Cluster: P-cumic alcohol dehydrogenase; n=3; Proteobacteria|Rep: P-cumic alcohol dehydrogenase - Pseudomonas putida Length = 252 Score = 59.7 bits (138), Expect = 3e-08 Identities = 49/149 (32%), Positives = 73/149 (48%), Gaps = 9/149 (6%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 KDKV +TGAATGIG ++VR L EG K + I D+ + ++ EL + + Sbjct: 4 KDKVAIVTGAATGIGNAIVRSYLAEGAK-VVIADV--KGAEAAAAELGE---DLALGVFA 57 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMN-------DSIGI--YKKAIEVNVTALI 352 DV+D + + A + G IDV++NNA + +SI + + K VNV Sbjct: 58 DVSDPDSTKQMAKAALDRFGKIDVLVNNAGIFTGLNYVPMESISVADWDKLYSVNVKG-- 115 Query: 353 TSTLKAIEIMGKHSGGKGGTVINVSSVAA 439 L A + G GG +IN++SV A Sbjct: 116 -PWLCASAVSAAMREGGGGKIINIASVIA 143 >UniRef50_A7DM07 Cluster: Short-chain dehydrogenase/reductase SDR; n=4; Alphaproteobacteria|Rep: Short-chain dehydrogenase/reductase SDR - Methylobacterium extorquens PA1 Length = 282 Score = 59.7 bits (138), Expect = 3e-08 Identities = 44/144 (30%), Positives = 69/144 (47%), Gaps = 5/144 (3%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV FITGAA+GIG + EG + +AI D EEA + L+ E+ G R DV Sbjct: 41 KVAFITGAASGIGRAAAIAFAREGAQ-VAITDRTEEALERLRAEIEGN-GGAVIAIRCDV 98 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIMG 385 + E + V+ G +D NNA + N + +++ A++ ++ L+ + Sbjct: 99 SLPEDVAAAVARTVERFGRLDCAFNNAGVENKAAPVHEIALD-EWDRILDINLRGTFVCM 157 Query: 386 KHSGGK-----GGTVINVSSVAAL 442 KH + GG V+N SS A + Sbjct: 158 KHEIAQMLRQGGGVVVNTSSGAGI 181 >UniRef50_A4AQP3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=1; Flavobacteriales bacterium HTCC2170|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Flavobacteriales bacterium HTCC2170 Length = 245 Score = 59.7 bits (138), Expect = 3e-08 Identities = 40/147 (27%), Positives = 74/147 (50%), Gaps = 6/147 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 KDK+ +TG A GIG++V + EG + I+D+ + G+++ + + G K +++ Sbjct: 4 KDKIAVVTGGARGIGQAVSELFAKEGAT-VIIMDLLPQ-GQAVAEGIIAS-GGKAEYHSL 60 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITST 361 VT++ G+ ++V + G ID++INNA + D S + IEVN+ + T Sbjct: 61 SVTNKSDVEGVFSSVNDKYGKIDILINNAGITRDRTLEKMSEAEWDAVIEVNLKGVFICT 120 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAAL 442 + M K G +++ +S L Sbjct: 121 QAVVPYM---KASKYGRIVSAASNVGL 144 >UniRef50_A4AN22 Cluster: Probable glucose 1-dehydrogenase; n=1; Flavobacteriales bacterium HTCC2170|Rep: Probable glucose 1-dehydrogenase - Flavobacteriales bacterium HTCC2170 Length = 268 Score = 59.7 bits (138), Expect = 3e-08 Identities = 41/143 (28%), Positives = 69/143 (48%), Gaps = 5/143 (3%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 K K V +TG + GIG + R L G + + E++ + L E+++ YG +T + Sbjct: 7 KGKRVLVTGGSRGIGAEICRKLAACGAEVFINYNSNEQSAQDLANEISNSYGVRTGIACA 66 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEI 379 DV+ E + + GGID+++NNA +SI +E +I LK + Sbjct: 67 DVSKAEQVKQMFLKMDGVMGGIDILVNNAG--TESIHHVLDLVEEEWDRVINVNLKGPFL 124 Query: 380 MGKHSGGK-----GGTVINVSSV 433 K +G + GG +IN+SS+ Sbjct: 125 CSKEAGDRMEKNGGGVIINISSI 147 >UniRef50_A4ABB5 Cluster: Short-chain dehydrogenase/reductase SDR; n=1; Congregibacter litoralis KT71|Rep: Short-chain dehydrogenase/reductase SDR - Congregibacter litoralis KT71 Length = 253 Score = 59.7 bits (138), Expect = 3e-08 Identities = 40/143 (27%), Positives = 70/143 (48%), Gaps = 3/143 (2%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 KDKV +TG A+GIG R L EG + + I DI E G+ + EL+S F + Sbjct: 6 KDKVALVTGGASGIGYETARSFLREGAR-VMIGDINLEQGRKVAEELSSL--GDIAFVEN 62 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIE---VNVTALITSTLKA 370 +VT E + V+ G +D+ +NNA ++ ++ + + + E + I Sbjct: 63 NVTAEASCQNAVEHTVKRFGRLDIAVNNAGVIGETKPLLELSAEGWQRTMNININGVFFG 122 Query: 371 IEIMGKHSGGKGGTVINVSSVAA 439 ++ GG++IN++S+A+ Sbjct: 123 LKAQVNQMLATGGSIINLASIAS 145 >UniRef50_A1SG64 Cluster: Short-chain dehydrogenase/reductase SDR; n=25; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Nocardioides sp. (strain BAA-499 / JS614) Length = 255 Score = 59.7 bits (138), Expect = 3e-08 Identities = 46/144 (31%), Positives = 72/144 (50%), Gaps = 5/144 (3%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 +VV +TGAA GIG +EG +A+LD+ E + +L G K DV Sbjct: 7 RVVVVTGAARGIGFGTATRFAEEGAS-VAVLDLDEASAAEAAAKLPVSGGAKAVGIGCDV 65 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAIEIM- 382 +D + VV E GGI V++NNA + D++ ++K E + ++ L+ +M Sbjct: 66 SDSAAAEAAVERVVAELGGIHVLVNNAGITRDNL-LFKMT-EDDWDLVMNVHLRGAFLMT 123 Query: 383 ---GKH-SGGKGGTVINVSSVAAL 442 KH K G ++N+SSV+AL Sbjct: 124 RAAQKHFVAQKYGKILNLSSVSAL 147 >UniRef50_A1R359 Cluster: Putative 3-oxoacyl-[acyl-carrier protein] reductase; n=1; Arthrobacter aurescens TC1|Rep: Putative 3-oxoacyl-[acyl-carrier protein] reductase - Arthrobacter aurescens (strain TC1) Length = 261 Score = 59.7 bits (138), Expect = 3e-08 Identities = 41/145 (28%), Positives = 74/145 (51%), Gaps = 6/145 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K V +TGA +G+G +V + L EG I + D++E++ + + NS + +DV Sbjct: 9 KTVMVTGAGSGLGAAVFKRFLLEGANVIGV-DLSEDSMARFR-DRNSVLSGQITLKVADV 66 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITSTLK 367 D + I+N V+E G +DV++NNA + S +++ ++VNV L +T Sbjct: 67 GDPDAIEAIINESVEELGALDVLVNNAGIAPTGPAATTSNELWRSVMKVNVDGLFYATRA 126 Query: 368 AIEIMGKHSGGKGGTVINVSSVAAL 442 A+ H G ++N +SV+ + Sbjct: 127 AL----PHLIQSQGNIVNTASVSGI 147 >UniRef50_A1FW82 Cluster: Short-chain dehydrogenase/reductase SDR precursor; n=8; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR precursor - Stenotrophomonas maltophilia R551-3 Length = 283 Score = 59.7 bits (138), Expect = 3e-08 Identities = 42/154 (27%), Positives = 71/154 (46%), Gaps = 9/154 (5%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 ++K+ +TGA GIG VR L GV H + E ++L ++ G + + Sbjct: 43 QNKIALVTGATRGIGAETVRQLAQAGV-HTLLAGRKRETAVEQALKLQAE-GLPVEAIQL 100 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM---------NDSIGIYKKAIEVNVTALI 352 DVTD + V Q G +D+++NNA +M S+ +K+ + NV AL+ Sbjct: 101 DVTDAASIAEAVEQVRQRHGRLDILVNNAGIMIENPAQAPSEQSLDTWKRTFDTNVYALV 160 Query: 353 TSTLKAIEIMGKHSGGKGGTVINVSSVAALTQSH 454 T + ++ + K G ++NVSS+ H Sbjct: 161 AVTQAFLPLVRQ---AKSGRIVNVSSMLGSQTLH 191 >UniRef50_A1ATN3 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Pelobacter|Rep: Short-chain dehydrogenase/reductase SDR - Pelobacter propionicus (strain DSM 2379) Length = 283 Score = 59.7 bits (138), Expect = 3e-08 Identities = 42/148 (28%), Positives = 77/148 (52%), Gaps = 10/148 (6%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV ITGA GIG ++ L +G + + D+ + + E+ ++ G K R+DV Sbjct: 24 KVAIITGAGRGIGRAIALRLGADGAA-MVVSDVNGDNATKVAEEIKAR-GGKAMALRTDV 81 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVT-ALITSTL 364 T E +++ V++ G +D+++ NA + N + I + + + VN A + T+ Sbjct: 82 TSEADVKDLIDTAVRQHGRLDIMVANAGIANIKMSIEMTGAEWDQIMAVNTKGAFLCDTM 141 Query: 365 KAIEIMGK-HS--GGKGGTVINVSSVAA 439 A +++ + HS G GG +IN +S+AA Sbjct: 142 AARQMIKQGHSETPGSGGKIINCASIAA 169 >UniRef50_Q4WR19 Cluster: Short chain dehydrogenase, putative; n=2; Trichocomaceae|Rep: Short chain dehydrogenase, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 257 Score = 59.7 bits (138), Expect = 3e-08 Identities = 42/137 (30%), Positives = 68/137 (49%), Gaps = 6/137 (4%) Frame = +2 Query: 38 ITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK-FYRSDVTDE 214 ITGAA G+G + L + I + DI E G + +LN +G T F+ D+++ Sbjct: 6 ITGAAQGVGLCIAEALAQRNYR-IVLSDIDTEKGPAAASKLNLTHGEGTAAFFHCDLSNL 64 Query: 215 EHFLGILNAVVQEQGGIDVVINNAALMND-----SIGIYKKAIEVNVTALITSTLKAIEI 379 +L+ ++ GG V+INNA + S + I VN+TA I +T +AI+ Sbjct: 65 REIDALLSFTIETMGGFSVLINNAGYLRAPFLALSAQDIQDMITVNLTAPIYATQQAIKY 124 Query: 380 MGKHSGGKGGTVINVSS 430 G+ G V++V+S Sbjct: 125 WDGLHQGQAGCVVSVTS 141 >UniRef50_Q9Z8P2 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=26; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Chlamydia pneumoniae (Chlamydophila pneumoniae) Length = 248 Score = 59.7 bits (138), Expect = 3e-08 Identities = 39/144 (27%), Positives = 74/144 (51%), Gaps = 6/144 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K V +TG + GIG +V++ L+ G + I + EE G+++ +E + G + F R DV Sbjct: 8 KKVIVTGGSRGIGLGIVKLFLENGAD-VEIWGLNEERGQAV-IESLTGLGGEVSFARVDV 65 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 367 + + + + ID+++NNA + D++ + ++ I N+T+L + Sbjct: 66 SHNGGVKDCVQKFLDKHNKIDILVNNAGITRDNLLMRMSEDDWQSVISTNLTSLYYTCSS 125 Query: 368 AIEIMGKHSGGKGGTVINVSSVAA 439 I M K + G++INV+S+ A Sbjct: 126 VIRHMIK---ARSGSIINVASIVA 146 >UniRef50_O67610 Cluster: 3-oxoacyl-[acyl-carrier-protein] reductase; n=9; Bacteria|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase - Aquifex aeolicus Length = 248 Score = 59.7 bits (138), Expect = 3e-08 Identities = 38/146 (26%), Positives = 69/146 (47%), Gaps = 6/146 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV +TG+ GIG ++ L G + I + E K++ E+ +KYG K ++ Sbjct: 8 KVSLVTGSTRGIGRAIAEKLASAG-STVIITGTSGERAKAVAEEIANKYGVKAHGVEMNL 66 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 367 EE + GID+++NNA + D + + +++ ++VN+T T Sbjct: 67 LSEESINKAFEEIYNLVDGIDILVNNAGITRDKLFLRMSLLDWEEVLKVNLTGTFLVTQN 126 Query: 368 AIEIMGKHSGGKGGTVINVSSVAALT 445 ++ M K + G ++N+SSV T Sbjct: 127 SLRKMIKQ---RWGRIVNISSVVGFT 149 >UniRef50_Q988B7 Cluster: 3-oxoacyl-(Acyl-carrier protein) reductase; n=1; Mesorhizobium loti|Rep: 3-oxoacyl-(Acyl-carrier protein) reductase - Rhizobium loti (Mesorhizobium loti) Length = 248 Score = 59.3 bits (137), Expect = 4e-08 Identities = 39/141 (27%), Positives = 71/141 (50%), Gaps = 6/141 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K +TGAA GIG+++ L +G + + DI E K+ + G K + +D+ Sbjct: 8 KTALVTGAAQGIGKAIAARLAADGAT-VIVSDINAEGAKAAAASI----GKKARAIAADI 62 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMN----DSIGI--YKKAIEVNVTALITSTLK 367 +D + + GGID+++NNA+++ D + + ++K I+VN+T T Sbjct: 63 SDPGSVKALFAEIQALTGGIDILVNNASIVPFVAWDDVDLDHWRKIIDVNLTGTFIVTRA 122 Query: 368 AIEIMGKHSGGKGGTVINVSS 430 + M + GK G VI+++S Sbjct: 123 GTDQM--RAAGKAGRVISIAS 141 >UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specificities; n=4; Bacteria|Rep: Dehydrogenases with different specificities - Thermoanaerobacter tengcongensis Length = 247 Score = 59.3 bits (137), Expect = 4e-08 Identities = 43/145 (29%), Positives = 71/145 (48%), Gaps = 6/145 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 +V F+TG + GIG ++ L +G +IAI + ++ VE K+G + DV Sbjct: 6 RVAFVTGGSRGIGRAIAVRLAKDGF-NIAITYVKDDKSAEEVVEEVKKHGVDALAIKCDV 64 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTLK 367 + + V++E G IDVV+NNA + D++ + + + I+VN+ Sbjct: 65 SKYHEVEKAVEKVIEEFGSIDVVVNNAGITKDNLILKMEEEEWDQVIDVNLKGAFNVIKF 124 Query: 368 AIEIMGKHSGGKGGTVINVSSVAAL 442 A + M K GK +IN+SSV L Sbjct: 125 ASKYMIKKRKGK---IINISSVVGL 146 >UniRef50_Q8EDE2 Cluster: Oxidoreductase, short chain dehydrogenase/reductase family; n=33; Bacteria|Rep: Oxidoreductase, short chain dehydrogenase/reductase family - Shewanella oneidensis Length = 254 Score = 59.3 bits (137), Expect = 4e-08 Identities = 40/150 (26%), Positives = 73/150 (48%), Gaps = 6/150 (4%) Frame = +2 Query: 8 SHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK 187 S+ + KV F+ G + GIG ++V+ L EG +A ++ EA L V+ G K Sbjct: 9 SNNLQGKVAFVQGGSRGIGAAIVKRLASEGAA-VAFTYVSSEAQSQLLVDEVIAQGGKAI 67 Query: 188 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTAL 349 ++D T+ E + GG+D+V+NNA ++ N ++ +++ + NV ++ Sbjct: 68 AIKADSTEPEAIRRAIRETKAHLGGLDIVVNNAGILIWDSIENLTLEDWERIVNTNVRSV 127 Query: 350 ITSTLKAIEIMGKHSGGKGGTVINVSSVAA 439 ++ +A M GG +IN+ S A Sbjct: 128 FVASQEAALHM-----NDGGRIINIGSTNA 152 >UniRef50_Q1NK00 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; delta proteobacterium MLMS-1|Rep: Short-chain dehydrogenase/reductase SDR - delta proteobacterium MLMS-1 Length = 275 Score = 59.3 bits (137), Expect = 4e-08 Identities = 37/117 (31%), Positives = 61/117 (52%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 202 DKVV +TGA+ GIG + R L G + AEE +++ E+N+ G + ++D Sbjct: 31 DKVVLVTGASRGIGAACARALAGCGAAVVVNYMQAEEQARAVAAEINAG-GGRALAIQAD 89 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKKAIEVNVTALITSTLKAI 373 V D E ++ +E G IDV++NNA + N I + ++ A +T +KA+ Sbjct: 90 VRDREAVEKMVQTAAREMGPIDVLVNNAHI-NFPIQPFTALAWPDIEAKLTGEIKAL 145 >UniRef50_Q0RTV0 Cluster: Short-chain dehydrogenase, SDR family; n=1; Frankia alni ACN14a|Rep: Short-chain dehydrogenase, SDR family - Frankia alni (strain ACN14a) Length = 276 Score = 59.3 bits (137), Expect = 4e-08 Identities = 37/146 (25%), Positives = 74/146 (50%), Gaps = 7/146 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 K +TG ++GIG + + EG H+ I DI +E G++ L G+ + +DV Sbjct: 8 KTAIVTGGSSGIGLASAEAFVAEGA-HVVIGDIQDERGRAAAERL----GDAALYVHTDV 62 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITSTL 364 +D++ +++ V+ GG+D++ NNA+ D G+ +++ + V + ++ Sbjct: 63 SDDDQVANLVDTAVRHFGGLDIMFNNASGAGDQAGLVDLGPDGLDRSLRLIVGSAVSGHR 122 Query: 365 KAIEIMGKHSGGKGGTVINVSSVAAL 442 A + + G+GG++I SS + L Sbjct: 123 HAARVFIEQ--GRGGSIITTSSGSGL 146 >UniRef50_Q0B254 Cluster: Short-chain dehydrogenase/reductase SDR; n=2; Burkholderia ambifaria AMMD|Rep: Short-chain dehydrogenase/reductase SDR - Burkholderia cepacia (strain ATCC 53795 / AMMD) Length = 252 Score = 59.3 bits (137), Expect = 4e-08 Identities = 45/150 (30%), Positives = 70/150 (46%), Gaps = 7/150 (4%) Frame = +2 Query: 23 DKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSD 202 DKV +TGA +GIG++ + EG K +AI EE G+ + E+ +G + F R+D Sbjct: 6 DKVALVTGATSGIGKATAMLFAREGAK-VAIAARREEEGRQVVREI-LDHGGEAIFVRTD 63 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI-------YKKAIEVNVTALITST 361 V E + V G +D+ NNA + + + + I+VN+T S Sbjct: 64 VAQAEDCAAAVARTVASFGKLDIAFNNAGITSFGRPVADTDEQAWSTVIDVNLTGTFLSM 123 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVAALTQS 451 I + K GG++IN+SS L S Sbjct: 124 KYEIPEILK---AGGGSIINMSSAYGLAGS 150 >UniRef50_A6VY27 Cluster: Short-chain dehydrogenase/reductase SDR; n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase SDR - Marinomonas sp. MWYL1 Length = 252 Score = 59.3 bits (137), Expect = 4e-08 Identities = 43/149 (28%), Positives = 76/149 (51%), Gaps = 7/149 (4%) Frame = +2 Query: 8 SHEWKDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTK 187 +++ +K +TG A+GIG + V +L G +AI D+ EEA + + + SKY K Sbjct: 3 NYQLDNKKAMVTGGASGIGLACVELLAYSGAD-VAIWDLHEEALEKAKQSI-SKYNVKCI 60 Query: 188 FYRSDVTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI--GIYK-----KAIEVNVTA 346 + DV+D E + +++ G +D+ +NNA + + G Y K I+VN Sbjct: 61 TIKVDVSDPESVKAAMAETLKQLGSLDIAVNNAGIGGPACKSGDYTTEDWLKVIDVNFNG 120 Query: 347 LITSTLKAIEIMGKHSGGKGGTVINVSSV 433 + +AI M K+ G++IN++S+ Sbjct: 121 VFYCQREAIAAMRKNG---SGSIINMASI 146 >UniRef50_A3HW24 Cluster: Oxidoreductase, short-chain dehydrogenase/reductase family protein; n=1; Algoriphagus sp. PR1|Rep: Oxidoreductase, short-chain dehydrogenase/reductase family protein - Algoriphagus sp. PR1 Length = 265 Score = 59.3 bits (137), Expect = 4e-08 Identities = 39/149 (26%), Positives = 78/149 (52%), Gaps = 6/149 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV+ +TG+ TGIG+++ + ++ EG K + I + E+ G+ + EL + + K + D+ Sbjct: 6 KVIIVTGSTTGIGKAIAKKVVSEGAK-VIIHGLEEDLGQQVVSELGA---DNAKLHIEDI 61 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMNDSI------GIYKKAIEVNVTALITSTLK 367 ++E +++ V+ G +D ++NNAA++ S + +EVN + T Sbjct: 62 SNEGAAQRLVDIAVKTWGKLDSIVNNAAIVAASTLFDTDKAFLNRILEVNTISPFLLTQA 121 Query: 368 AIEIMGKHSGGKGGTVINVSSVAALTQSH 454 AI + ++ G V+N+ S+ A + H Sbjct: 122 AISQLIQNK----GAVLNIGSINAYSGEH 146 >UniRef50_A0PSE4 Cluster: Short-chain type dehydrogenase; n=12; Corynebacterineae|Rep: Short-chain type dehydrogenase - Mycobacterium ulcerans (strain Agy99) Length = 285 Score = 59.3 bits (137), Expect = 4e-08 Identities = 46/145 (31%), Positives = 76/145 (52%), Gaps = 6/145 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 ++KV+ ITG A GIG + L G K +AI D+ E A K +L + K Sbjct: 12 RNKVIVITGGARGIGLATATALHKLGAK-VAIGDVGEPAVKEAGADLGLEVYGKL----- 65 Query: 200 DVTDEEHFLGILNAVVQEQGGIDVVINNAALM------NDSIGIYKKAIEVNVTALITST 361 DVTD F L+ V ++ G +DV++NNA +M ++ + ++ +++NV ++ + Sbjct: 66 DVTDPNSFSDFLDQVERQLGPLDVLVNNAGIMPVGRIVDEPDSVTRRILDINVYGVMVGS 125 Query: 362 LKAIEIMGKHSGGKGGTVINVSSVA 436 A + M G+ G VINV+S+A Sbjct: 126 KLAAQRMVPR--GR-GHVINVASLA 147 >UniRef50_Q7Q3Q2 Cluster: ENSANGP00000007118; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000007118 - Anopheles gambiae str. PEST Length = 245 Score = 59.3 bits (137), Expect = 4e-08 Identities = 41/148 (27%), Positives = 76/148 (51%), Gaps = 7/148 (4%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRS 199 + +V ITG G+G ++ ++ G H+ ++DI +A + EL +YG + YR Sbjct: 48 RGQVALITGGGNGLGRAMAQLFAARGC-HLVLVDIDLQAAERTAEELRQQYGVAARAYRV 106 Query: 200 DVTDEEHFLGILNAVVQEQGG-IDVVINNA-----ALMNDS-IGIYKKAIEVNVTALITS 358 DV+ E + + ++ G +D++INNA A +NDS + I+VN+ + + Sbjct: 107 DVSQYEQCRALGEQIERDGAGPVDILINNAGLIMFAFVNDSDVERANSVIDVNMKSHVWM 166 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSVAAL 442 T ++ M K K G +I +SS++ + Sbjct: 167 TKVFLDGMIKR---KRGHIIGISSMSGM 191 >UniRef50_Q0UTY3 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 313 Score = 59.3 bits (137), Expect = 4e-08 Identities = 44/142 (30%), Positives = 75/142 (52%), Gaps = 7/142 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDI-AEEAGKSLQVELNSKYGNKTKFYRSD 202 KV ITGA GIG ++ L G ++AILD+ ++ K+ + L ++G K + D Sbjct: 33 KVALITGAGQGIGAAIAEALAKSGA-NVAILDLNTDKLVKTKEACL--QHGGKVADFACD 89 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGI------YKKAIEVNVTALITSTL 364 VT+E +++AV ++ G IDV++NNA + + I + + IEVN A + Sbjct: 90 VTNEHKIKEVIDAVEKQLGPIDVLVNNAGIFDQRPFIMSTFDGFWRQIEVNFKAPLMLIH 149 Query: 365 KAIEIMGKHSGGKGGTVINVSS 430 + + M + GG +IN++S Sbjct: 150 QMLPRMRERG---GGCIINIAS 168 >UniRef50_Q0UAH4 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 266 Score = 59.3 bits (137), Expect = 4e-08 Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 5/142 (3%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVEL-NSKYGNKTKFYRSD 202 ++V +TGA +GIG + LL G H+ + + GK+ L N +F D Sbjct: 7 EIVLVTGANSGIGFEIAHQLLARGTYHVFLSARSSSKGKAALENLQNRNLPGSIEFLHLD 66 Query: 203 VTDEEHFLGILNAVVQEQGGIDVVINNAALMNDSIGIYKK----AIEVNVTALITSTLKA 370 V +EH + + + G +D+++NNAA+ + G ++ + ++N T T Sbjct: 67 VQSDEHIANAASRIAEAHGKLDILVNNAAIAFSTDGTERERLRDSFDINATGPYLLTKAL 126 Query: 371 IEIMGKHSGGKGGTVINVSSVA 436 I + K S + +IN+SS A Sbjct: 127 IPALRKSSNPR---IINISSGA 145 >UniRef50_Q5UYC2 Cluster: 3-oxoacyl-[acyl-carrier protein] reductase; n=2; Halobacteriaceae|Rep: 3-oxoacyl-[acyl-carrier protein] reductase - Haloarcula marismortui (Halobacterium marismortui) Length = 254 Score = 59.3 bits (137), Expect = 4e-08 Identities = 43/146 (29%), Positives = 70/146 (47%), Gaps = 9/146 (6%) Frame = +2 Query: 20 KDKVVFITGAATGIGESVVRILLDEGVKHIAILDIAE---EAGKSLQVELNSKYGNKTKF 190 +DKV +TG A+G G ++ R + G + + D + E GK + ++ F Sbjct: 6 EDKVAVVTGGASGFGRAICRRYAEHGA-DVIVADRQQDPREGGKPTHELVEAETDRTAHF 64 Query: 191 YRSDVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALI 352 DVTD + L + A +E GGID+++NNA + + Y + ++VN + Sbjct: 65 VECDVTDPDD-LEVAVAAAEELGGIDIMVNNAGISEIADFYETTEEDYDRLMDVNTKGVF 123 Query: 353 TSTLKAIEIMGKHSGGKGGTVINVSS 430 A E M ++ GGTVIN+SS Sbjct: 124 FGAQVATEAMRENG---GGTVINMSS 146 >UniRef50_O29061 Cluster: 2-deoxy-D-gluconate 3-dehydrogenase; n=1; Archaeoglobus fulgidus|Rep: 2-deoxy-D-gluconate 3-dehydrogenase - Archaeoglobus fulgidus Length = 281 Score = 59.3 bits (137), Expect = 4e-08 Identities = 42/145 (28%), Positives = 73/145 (50%), Gaps = 9/145 (6%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAI---LDIAEEAGKSLQVELNSKYGNKTKFYR 196 KV +TGA G+G + L D G + + L++ E+ +S++ K G + + Sbjct: 36 KVAIVTGATGGLGGPIALGLADFGCDVVVVGRRLEVLEKLKESIE-----KLGQRALAVK 90 Query: 197 SDVTDEEHFLGILNAVVQEQGGIDVVINNAAL------MNDSIGIYKKAIEVNVTALITS 358 D+T EE ++N V+E G ID+++N A + + + K ++ NVT + Sbjct: 91 CDITSEEDVANLVNRTVEEFGRIDILVNCAGINIPKPAEEYPLEDWNKVMDANVTGVFLV 150 Query: 359 TLKAIEIMGKHSGGKGGTVINVSSV 433 + ++M K +GGK +INVSSV Sbjct: 151 CREVGKVMVKQNGGK---IINVSSV 172 >UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2; Corynebacterium glutamicum|Rep: Putative oxidoreductase - Corynebacterium glutamicum (Brevibacterium flavum) Length = 279 Score = 58.8 bits (136), Expect = 5e-08 Identities = 41/146 (28%), Positives = 73/146 (50%), Gaps = 6/146 (4%) Frame = +2 Query: 26 KVVFITGAATGIGESVVRILLDEGVKHIAILDIAEEAGKSLQVELNSKYGNKTKFYRSDV 205 KV FITGAA+G+G S R+L G K + I D+ +E G+ L E+ + K + +V Sbjct: 38 KVAFITGAASGMGASHARVLAAHGAK-VVITDLNDELGQELVKEIGEE---KAHYVHLNV 93 Query: 206 TDEEHFLGILNAVVQEQGGIDVVINNAALMND------SIGIYKKAIEVNVTALITSTLK 367 T E + + ++ G ID +INNA + + + + K I +++ Sbjct: 94 TSFEEWEVAVQKALERFGKIDTLINNAGIFSSGSVEDATAADWDKTIAIDLNGTFYGMKA 153 Query: 368 AIEIMGKHSGGKGGTVINVSSVAALT 445 A+ + ++ ++IN+SS+A +T Sbjct: 154 ALPALKEN---PTASIINISSIAGVT 176 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 447,955,708 Number of Sequences: 1657284 Number of extensions: 8447054 Number of successful extensions: 33213 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 30327 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 31384 length of database: 575,637,011 effective HSP length: 94 effective length of database: 419,852,315 effective search space used: 24771286585 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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