Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= heS30428
(385 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VJ31 Cluster: CG10623-PA; n=11; Diptera|Rep: CG10623-... 119 2e-26
UniRef50_Q2F5Q8 Cluster: Homocysteine S-methyltransferase; n=4; ... 110 1e-23
UniRef50_UPI0000519B36 Cluster: PREDICTED: similar to CG10621-PA... 93 2e-18
UniRef50_UPI00015B4DEA Cluster: PREDICTED: similar to homocystei... 89 3e-17
UniRef50_Q5PNQ3 Cluster: Novel protein containing a homocysteine... 84 1e-15
UniRef50_Q0TXM4 Cluster: Putative uncharacterized protein; n=1; ... 75 4e-13
UniRef50_Q3CZT7 Cluster: Homocysteine S-methyltransferase; n=15;... 73 2e-12
UniRef50_A7S7I8 Cluster: Predicted protein; n=2; Nematostella ve... 71 8e-12
UniRef50_Q47690 Cluster: Homocysteine S-methyltransferase; n=20;... 70 2e-11
UniRef50_Q4S116 Cluster: Chromosome 1 SCAF14770, whole genome sh... 69 4e-11
UniRef50_Q5FKC1 Cluster: Homocysteine S-methyltransferase; n=2; ... 68 7e-11
UniRef50_A5VKC8 Cluster: Homocysteine S-methyltransferase; n=2; ... 68 7e-11
UniRef50_O31463 Cluster: YbgG protein; n=6; Firmicutes|Rep: YbgG... 65 5e-10
UniRef50_Q4Q0C9 Cluster: Homocysteine S-methyltransferase, putat... 61 6e-09
UniRef50_Q88XC1 Cluster: Homocysteine S-methyltransferase; n=2; ... 61 8e-09
UniRef50_Q6BZK6 Cluster: Debaryomyces hansenii chromosome A of s... 60 2e-08
UniRef50_Q8LAX0 Cluster: Homocysteine S-methyltransferase 3; n=3... 59 3e-08
UniRef50_Q1GBT8 Cluster: Homocysteine S-methyltransferase; n=2; ... 57 1e-07
UniRef50_UPI000050FD2A Cluster: COG2040: Homocysteine/selenocyst... 55 4e-07
UniRef50_Q59QD2 Cluster: Putative uncharacterized protein SAM4; ... 54 1e-06
UniRef50_Q7D740 Cluster: Homocysteine S-methyltransferase; n=14;... 52 5e-06
UniRef50_A3TGH3 Cluster: Homocysteine methyltransferase; n=1; Ja... 52 5e-06
UniRef50_A5CB34 Cluster: Putative uncharacterized protein; n=1; ... 52 5e-06
UniRef50_Q0BQM8 Cluster: Homocysteine S-methyltransferase; n=1; ... 50 2e-05
UniRef50_Q49V93 Cluster: Putative homocysteine S-methyltransfera... 50 2e-05
UniRef50_A5DTG6 Cluster: Putative uncharacterized protein; n=1; ... 50 2e-05
UniRef50_UPI0000E4900F Cluster: PREDICTED: similar to 5-methylte... 48 6e-05
UniRef50_A3LQC9 Cluster: AdoMet-homocysteine methyltransferase; ... 46 2e-04
UniRef50_Q4PDM6 Cluster: Putative uncharacterized protein; n=1; ... 46 3e-04
UniRef50_A6G853 Cluster: Homocysteine methyltransferase; n=1; Pl... 44 8e-04
UniRef50_Q5KA93 Cluster: Homocysteine S-methyltransferase, putat... 42 0.003
UniRef50_A5DCB0 Cluster: Putative uncharacterized protein; n=1; ... 42 0.005
UniRef50_Q6C0D6 Cluster: Yarrowia lipolytica chromosome F of str... 40 0.012
UniRef50_Q748T0 Cluster: 5-methyltetrahydrofolate-homocysteine m... 39 0.028
UniRef50_A5K8K1 Cluster: Putative uncharacterized protein; n=1; ... 39 0.028
UniRef50_Q1DSS3 Cluster: Putative uncharacterized protein; n=1; ... 38 0.049
UniRef50_Q08985 Cluster: Homocysteine S-methyltransferase 2; n=9... 37 0.15
UniRef50_Q2JJL4 Cluster: Methionine synthase; n=25; Cyanobacteri... 36 0.26
UniRef50_Q753B4 Cluster: AFR410Wp; n=1; Eremothecium gossypii|Re... 36 0.26
UniRef50_A1SWN6 Cluster: Homocysteine S-methyltransferase; n=2; ... 36 0.35
UniRef50_Q2TXK9 Cluster: Predicted protein; n=2; Trichocomaceae|... 36 0.35
UniRef50_A3UPV1 Cluster: Homocysteine S-methyltransferase family... 34 0.81
UniRef50_Q4WFR2 Cluster: Homocysteine S-methyltransferase, putat... 34 0.81
UniRef50_A3JFK5 Cluster: Putative uncharacterized protein; n=1; ... 34 1.1
UniRef50_Q8I585 Cluster: Putative uncharacterized protein; n=2; ... 34 1.1
UniRef50_Q2S678 Cluster: Vitamin B12-dependent methionine syntha... 33 1.4
UniRef50_A7C1C8 Cluster: 5-methyltetrahydrofolate--homocysteine ... 33 1.4
UniRef50_Q30ZI4 Cluster: Vitamin B12-dependent methionine syntha... 33 1.9
UniRef50_Q4Y025 Cluster: Putative uncharacterized protein; n=4; ... 33 1.9
UniRef50_Q7SFT2 Cluster: Putative uncharacterized protein NCU007... 33 1.9
UniRef50_A4J6L9 Cluster: Homocysteine S-methyltransferase; n=1; ... 33 2.5
UniRef50_A3XRC5 Cluster: Oxidoreductase; n=13; Bacteroidetes|Rep... 33 2.5
UniRef50_A6S563 Cluster: Putative uncharacterized protein; n=2; ... 33 2.5
UniRef50_A2R696 Cluster: Contig An15c0240, complete genome; n=6;... 33 2.5
UniRef50_UPI0000DAE3F2 Cluster: hypothetical protein Rgryl_01000... 32 3.3
UniRef50_Q0LM71 Cluster: Methylenetetrahydrofolate reductase; n=... 32 3.3
UniRef50_Q01YW7 Cluster: Methionine synthase; n=2; Bacteria|Rep:... 32 3.3
UniRef50_A6CD85 Cluster: Fructose-1-phosphate kinase and related... 32 3.3
UniRef50_A5FJM4 Cluster: Glucan endo-1,6-beta-glucosidase; n=2; ... 32 3.3
UniRef50_A4R5G4 Cluster: Putative uncharacterized protein; n=1; ... 32 3.3
UniRef50_Q9ZE64 Cluster: Putative uncharacterized protein RP083;... 32 4.3
UniRef50_Q98KX0 Cluster: Mlr1281 protein; n=4; Proteobacteria|Re... 32 4.3
UniRef50_Q7M929 Cluster: S-METHYLTRANSFERASE; n=1; Wolinella suc... 32 4.3
UniRef50_Q5FP86 Cluster: 5-Methyltetrahydrofolate-S-homocysteine... 32 4.3
UniRef50_Q0LZ78 Cluster: Putative uncharacterized protein; n=1; ... 32 4.3
UniRef50_A7AL74 Cluster: Putative uncharacterized protein; n=1; ... 32 4.3
UniRef50_A4B5J7 Cluster: Homocysteine S-methyltransferase family... 32 4.3
UniRef50_Q4GZ92 Cluster: Homocysteine S-methyltransferase, putat... 32 4.3
UniRef50_A7TSR2 Cluster: Putative uncharacterized protein; n=1; ... 32 4.3
UniRef50_P43822 Cluster: Glycyl-tRNA synthetase beta chain; n=17... 32 4.3
UniRef50_Q9KCE2 Cluster: Methylenetetrahydrofolate reductase; n=... 31 5.7
UniRef50_Q2W1T1 Cluster: ABC-type branched-chain amino acid tran... 31 5.7
UniRef50_A6QBA6 Cluster: 5-methyltetrahydrofolate--homocysteine ... 31 5.7
UniRef50_A6PRW5 Cluster: Methylenetetrahydrofolate reductase; n=... 31 5.7
UniRef50_Q4DI99 Cluster: Homocysteine S-methyltransferase, putat... 31 5.7
UniRef50_Q22V72 Cluster: Putative uncharacterized protein; n=1; ... 31 5.7
UniRef50_P57905 Cluster: Glycyl-tRNA synthetase beta chain; n=47... 31 5.7
UniRef50_UPI0000E47473 Cluster: PREDICTED: hypothetical protein;... 31 7.5
UniRef50_Q7VBY3 Cluster: 5-methyltetrahydrofolate--homocysteine ... 31 7.5
UniRef50_Q1IL23 Cluster: Methylenetetrahydrofolate reductase; n=... 31 7.5
UniRef50_A7HBZ7 Cluster: Homocysteine S-methyltransferase; n=2; ... 31 7.5
UniRef50_A5Z6N8 Cluster: Putative uncharacterized protein; n=1; ... 31 7.5
UniRef50_A0NPW7 Cluster: Periplasmic glucan biosynthesis protein... 31 7.5
UniRef50_Q2FRP4 Cluster: Pre-mRNA processing ribonucleoprotein, ... 31 7.5
UniRef50_Q88X64 Cluster: Methylenetetrahydrofolate reductase; n=... 31 9.9
UniRef50_A3XF15 Cluster: Secreted hemolysin-type calcium-binding... 31 9.9
>UniRef50_Q9VJ31 Cluster: CG10623-PA; n=11; Diptera|Rep: CG10623-PA
- Drosophila melanogaster (Fruit fly)
Length = 331
Score = 119 bits (287), Expect = 2e-26
Identities = 55/85 (64%), Positives = 72/85 (84%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
HLDFLR GAD+I+TNTYQ+SVEGFV++LGVT+E+G ELI ++VQLAKQA+ YL E
Sbjct: 55 HLDFLRNGADIILTNTYQSSVEGFVKYLGVTRERGVELIQKSVQLAKQAKEQYLSEIGSE 114
Query: 182 VQNDDIPLIVGSVGPYGAHLHDGSD 256
++ +PLI+GS+GPYGA+LHDGS+
Sbjct: 115 AES-ALPLIMGSIGPYGAYLHDGSE 138
Score = 54.8 bits (126), Expect = 5e-07
Identities = 24/43 (55%), Positives = 30/43 (69%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
Y G+YAD S E +R WH+ RI+ + AGVD LALET+PC E
Sbjct: 139 YTGNYADKMSKEELRAWHKTRIEICLAAGVDGLALETLPCLME 181
>UniRef50_Q2F5Q8 Cluster: Homocysteine S-methyltransferase; n=4;
Endopterygota|Rep: Homocysteine S-methyltransferase -
Bombyx mori (Silk moth)
Length = 325
Score = 110 bits (264), Expect = 1e-23
Identities = 52/85 (61%), Positives = 66/85 (77%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
HLDFLRAG+D+I TNTYQASV+G V+HL +T E+ YELI AV+ A+ AR LYL+E ++
Sbjct: 52 HLDFLRAGSDIIETNTYQASVDGLVKHLNLTVEESYELIKSAVEFARTARDLYLQECQES 111
Query: 182 VQNDDIPLIVGSVGPYGAHLHDGSD 256
+ PLI GSVGPYGA+LHD S+
Sbjct: 112 NLSGRKPLIAGSVGPYGAYLHDTSE 136
Score = 70.5 bits (165), Expect = 1e-11
Identities = 30/43 (69%), Positives = 36/43 (83%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
Y G+YAD T+ ET++ WHR RIQALVEAGVD+LA ETIPC +E
Sbjct: 137 YTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKE 179
>UniRef50_UPI0000519B36 Cluster: PREDICTED: similar to CG10621-PA;
n=2; Apis mellifera|Rep: PREDICTED: similar to
CG10621-PA - Apis mellifera
Length = 320
Score = 93.1 bits (221), Expect = 2e-18
Identities = 46/89 (51%), Positives = 63/89 (70%), Gaps = 4/89 (4%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
HLDFL+AGAD+I TNTYQAS+ ++HL ++KE+ +L+ +AV LAK A Y +E
Sbjct: 44 HLDFLKAGADIIETNTYQASIPSLMKHLSISKEESIKLLHKAVHLAKTAVNDYTKE---V 100
Query: 182 VQNDDI----PLIVGSVGPYGAHLHDGSD 256
+ N+D+ P+IV S GPYGA LHDGS+
Sbjct: 101 INNNDVENKNPMIVASCGPYGASLHDGSE 129
Score = 58.4 bits (135), Expect = 4e-08
Identities = 23/43 (53%), Positives = 32/43 (74%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
Y+G+Y T E + +WH+ RI A++ AG+DLLALETIPC +E
Sbjct: 130 YNGAYGKITPRENIIQWHKSRIDAIINAGIDLLALETIPCYQE 172
>UniRef50_UPI00015B4DEA Cluster: PREDICTED: similar to homocysteine
S-methyltransferase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to homocysteine S-methyltransferase -
Nasonia vitripennis
Length = 341
Score = 89.0 bits (211), Expect = 3e-17
Identities = 41/85 (48%), Positives = 62/85 (72%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
HLD+LRAG+ +I T TYQAS+ G+V++L T+E+ +LI AV+LAK+A +Y EE +
Sbjct: 64 HLDYLRAGSHVIETATYQASIPGYVKYLDRTEEEALQLIKTAVELAKKAVRVYKEEIKGK 123
Query: 182 VQNDDIPLIVGSVGPYGAHLHDGSD 256
++ P++ GS+GPY A+LHD S+
Sbjct: 124 DVSNPEPMVAGSIGPYAAYLHDCSE 148
Score = 62.1 bits (144), Expect = 4e-09
Identities = 25/41 (60%), Positives = 33/41 (80%)
Frame = +1
Query: 262 GSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
GSYA+ S++++ EWHRPR +AL+ GVDLLA+ETIPC E
Sbjct: 152 GSYANIESMDSIVEWHRPRFEALINGGVDLLAIETIPCARE 192
>UniRef50_Q5PNQ3 Cluster: Novel protein containing a homocysteine
S-methyltransferase domain; n=7; Euteleostomi|Rep: Novel
protein containing a homocysteine S-methyltransferase
domain - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 318
Score = 83.8 bits (198), Expect = 1e-15
Identities = 39/85 (45%), Positives = 60/85 (70%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H +L++G+D+I T TYQAS+EGFV++LGV E+ ++ AVQLAK+ + ++ +
Sbjct: 52 HYRYLQSGSDVITTATYQASIEGFVKYLGVQPEEAQHMMMSAVQLAKETVSEFISQ--SP 109
Query: 182 VQNDDIPLIVGSVGPYGAHLHDGSD 256
+ + PL+ GSVGPYG+ LHDGS+
Sbjct: 110 MSDRREPLVAGSVGPYGSFLHDGSE 134
Score = 59.3 bits (137), Expect = 2e-08
Identities = 23/43 (53%), Positives = 34/43 (79%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
Y G+Y D ++E +++WHRP+IQ LV+AG DL+A+ETIP +E
Sbjct: 135 YTGAYEDKMTVEELKDWHRPQIQCLVKAGADLVAMETIPGLKE 177
>UniRef50_Q0TXM4 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 319
Score = 75.4 bits (177), Expect = 4e-13
Identities = 39/93 (41%), Positives = 59/93 (63%), Gaps = 8/93 (8%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYL------ 163
HLD+ RAGA++ IT +YQAS+ G V+HLG+ + + +++ ++VQLA +AR Y+
Sbjct: 56 HLDYYRAGANIAITASYQASIPGLVKHLGLGENEAKDVVKKSVQLAIEARDEYVQSKLEE 115
Query: 164 --EEYRDYVQNDDIPLIVGSVGPYGAHLHDGSD 256
E D + + GSVGPYGA+L DGS+
Sbjct: 116 SCERSVDAASLREDLFVAGSVGPYGAYLSDGSE 148
Score = 47.2 bits (107), Expect = 1e-04
Identities = 23/43 (53%), Positives = 30/43 (69%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
Y G Y + E M+++HR R+QALV+AGVD+LA ETIP E
Sbjct: 149 YRGDY--DVAHEAMKDFHRGRVQALVDAGVDVLACETIPSRRE 189
>UniRef50_Q3CZT7 Cluster: Homocysteine S-methyltransferase; n=15;
Streptococcus|Rep: Homocysteine S-methyltransferase -
Streptococcus agalactiae H36B
Length = 351
Score = 72.9 bits (171), Expect = 2e-12
Identities = 38/86 (44%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H D++RAGAD++ T+TYQA+++G + +GV++ Q +LI VQLAK R +
Sbjct: 89 HEDYIRAGADIVTTSTYQATLQGLAQ-VGVSESQAEDLIRLTVQLAKAVREQVWKSLTKE 147
Query: 182 VQNDDI-PLIVGSVGPYGAHLHDGSD 256
+++ I PLI G VGPY A L DGS+
Sbjct: 148 EKSERIYPLISGDVGPYAAFLADGSE 173
Score = 41.1 bits (92), Expect = 0.007
Identities = 24/48 (50%), Positives = 31/48 (64%), Gaps = 3/48 (6%)
Frame = +1
Query: 250 FRYDGS-YADTTSI--ETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
F DGS Y I E ++ +HR RI+ L++ GVDLLALETIP +E
Sbjct: 167 FLADGSEYTGLYDIYKEGLKNFHRHRIELLLDEGVDLLALETIPNAQE 214
>UniRef50_A7S7I8 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 265
Score = 70.9 bits (166), Expect = 8e-12
Identities = 36/85 (42%), Positives = 55/85 (64%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H FL G+D+I T TYQAS+ GF +HLGVT ++ +LI R V +A+++ ++E+ D
Sbjct: 25 HKSFLTHGSDIITTATYQASISGFCKHLGVTADEARKLIQRGVHIARES----VDEFWD- 79
Query: 182 VQNDDIPLIVGSVGPYGAHLHDGSD 256
++ + P + GSV PYG DGS+
Sbjct: 80 -KHSNSPQVAGSVCPYGTCQSDGSE 103
Score = 63.7 bits (148), Expect = 1e-09
Identities = 26/43 (60%), Positives = 34/43 (79%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
Y G+Y DT +I+ + +WHRP+IQALVE G+DLLA ETIP +E
Sbjct: 104 YHGNYVDTMTIKNLMDWHRPQIQALVETGLDLLAFETIPAQKE 146
>UniRef50_Q47690 Cluster: Homocysteine S-methyltransferase; n=20;
Bacteria|Rep: Homocysteine S-methyltransferase -
Escherichia coli (strain K12)
Length = 310
Score = 69.7 bits (163), Expect = 2e-11
Identities = 40/85 (47%), Positives = 54/85 (63%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
HLD+ RAGA IT +YQA+ GF G+ + Q LI ++V+LA++AR YL E
Sbjct: 55 HLDYYRAGAQCAITASYQATPAGFAAR-GLDEAQSKALIGKSVELARKAREAYLAENP-- 111
Query: 182 VQNDDIPLIVGSVGPYGAHLHDGSD 256
Q + L+ GSVGPYGA+L DGS+
Sbjct: 112 -QAGTL-LVAGSVGPYGAYLADGSE 134
Score = 45.6 bits (103), Expect = 3e-04
Identities = 21/43 (48%), Positives = 29/43 (67%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
Y G Y S+E + +HRPR++AL++AG DLLA ET+P E
Sbjct: 135 YRGDYH--CSVEAFQAFHRPRVEALLDAGADLLACETLPNFSE 175
>UniRef50_Q4S116 Cluster: Chromosome 1 SCAF14770, whole genome
shotgun sequence; n=4; Euteleostomi|Rep: Chromosome 1
SCAF14770, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 372
Score = 68.5 bits (160), Expect = 4e-11
Identities = 45/107 (42%), Positives = 59/107 (55%), Gaps = 22/107 (20%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYL--EEYR 175
H FL +GAD+I T TYQASVEGF++HL V+ E ELI VQLAK+A ++
Sbjct: 56 HCRFLLSGADVISTATYQASVEGFMDHLNVSSEGAKELIMSGVQLAKEAVESFVPGTNPN 115
Query: 176 DYVQNDD--------------------IPLIVGSVGPYGAHLHDGSD 256
VQ+ + PL+ GS+GPYGA LH+GS+
Sbjct: 116 TTVQSGEGKVNSEGSEGLAGQCSSGRRCPLVAGSLGPYGAFLHNGSE 162
Score = 50.8 bits (116), Expect = 9e-06
Identities = 19/43 (44%), Positives = 29/43 (67%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
Y G YA+ S++ ++ WHRP+++ L A D+LA ETIP +E
Sbjct: 163 YTGDYAEKMSVQELKAWHRPQVECLAAAEADVLAFETIPSIKE 205
>UniRef50_Q5FKC1 Cluster: Homocysteine S-methyltransferase; n=2;
Lactobacillus|Rep: Homocysteine S-methyltransferase -
Lactobacillus acidophilus
Length = 310
Score = 67.7 bits (158), Expect = 7e-11
Identities = 36/85 (42%), Positives = 55/85 (64%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H+++ ++GA + ITNTYQA+V+ F +H G + E +LI AVQ+AK+AR ++Y+
Sbjct: 50 HMNYFKSGAQMTITNTYQANVQAFKKH-GYSDEHTKKLITDAVQIAKKAR----DDYQ-- 102
Query: 182 VQNDDIPLIVGSVGPYGAHLHDGSD 256
Q + SVGPYGA+L DG +
Sbjct: 103 TQTGKHNWVAASVGPYGAYLSDGDE 127
>UniRef50_A5VKC8 Cluster: Homocysteine S-methyltransferase; n=2;
Lactobacillus reuteri|Rep: Homocysteine
S-methyltransferase - Lactobacillus reuteri F275
Length = 310
Score = 67.7 bits (158), Expect = 7e-11
Identities = 36/85 (42%), Positives = 56/85 (65%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H ++ +AG L IT+TYQA+V F+++ G +K++ + LI RAV LAK+AR Y +E Y
Sbjct: 50 HQEYFKAGDRLAITDTYQANVPAFIKN-GYSKQEAHSLIQRAVVLAKEARDEYQQETGIY 108
Query: 182 VQNDDIPLIVGSVGPYGAHLHDGSD 256
+ G++GPYGA+L +GS+
Sbjct: 109 ------NYVAGALGPYGAYLANGSE 127
Score = 35.9 bits (79), Expect = 0.26
Identities = 18/43 (41%), Positives = 30/43 (69%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
Y G+Y +T IE +++HRPR+ ++ GVD++A+ET P +E
Sbjct: 128 YSGAYHLST-IE-YQQFHRPRLTDILTVGVDVIAIETQPRLDE 168
>UniRef50_O31463 Cluster: YbgG protein; n=6; Firmicutes|Rep: YbgG
protein - Bacillus subtilis
Length = 315
Score = 64.9 bits (151), Expect = 5e-10
Identities = 37/87 (42%), Positives = 53/87 (60%), Gaps = 2/87 (2%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLY--LEEYR 175
H D+ AGAD IT +YQ++ EGF G+++ + LI +V +A +AR + LEE R
Sbjct: 52 HTDYFAAGADCAITASYQSTFEGFAAR-GLSEAEARRLIELSVSIAAEARDEFWSLEENR 110
Query: 176 DYVQNDDIPLIVGSVGPYGAHLHDGSD 256
N P+I S+GPYGA+L DGS+
Sbjct: 111 ---LNRPKPIIAASIGPYGAYLADGSE 134
Score = 50.8 bits (116), Expect = 9e-06
Identities = 24/43 (55%), Positives = 32/43 (74%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
Y G+YA S + + E+HRPR++AL+EAG D+LA ETIPC E
Sbjct: 135 YRGNYA--ISEDELIEFHRPRMKALIEAGADVLACETIPCLTE 175
>UniRef50_Q4Q0C9 Cluster: Homocysteine S-methyltransferase,
putative; n=3; Leishmania|Rep: Homocysteine
S-methyltransferase, putative - Leishmania major
Length = 339
Score = 61.3 bits (142), Expect = 6e-09
Identities = 35/84 (41%), Positives = 52/84 (61%)
Frame = +2
Query: 5 LDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYV 184
L +LRAGA IIT +YQ + + +EH +T++ I +V++A+ AR +L R+
Sbjct: 70 LAYLRAGARCIITASYQITPQSLMEHRRLTEDAAVAAIEESVRIAQSARERHL---REKP 126
Query: 185 QNDDIPLIVGSVGPYGAHLHDGSD 256
Q I + GSVGPYGA+L DGS+
Sbjct: 127 QAAPI-FVAGSVGPYGAYLADGSE 149
Score = 39.9 bits (89), Expect = 0.016
Identities = 21/43 (48%), Positives = 26/43 (60%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
Y G Y S E +E+HR RI AL+ AG D+LA+ET P E
Sbjct: 150 YRGDYV--RSAEEFKEFHRLRIAALLRAGADVLAIETQPSAAE 190
>UniRef50_Q88XC1 Cluster: Homocysteine S-methyltransferase; n=2;
Bacteria|Rep: Homocysteine S-methyltransferase -
Lactobacillus plantarum
Length = 309
Score = 60.9 bits (141), Expect = 8e-09
Identities = 40/94 (42%), Positives = 54/94 (57%), Gaps = 1/94 (1%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H +L AGA ++ TNTYQA+V F E G+ Q +LI +AV +A AR +
Sbjct: 51 HQSYLDAGAKIMTTNTYQANVPAF-EQAGIAAVQARQLIQQAVTIAHTARDA------SH 103
Query: 182 VQNDDIPLIVGSVGPYGAHLHDGSD-TMAVMQTP 280
V + +I GS+GPYGA+L DGS+ T A TP
Sbjct: 104 VTD---AVIAGSIGPYGAYLADGSEYTGAYQLTP 134
Score = 38.7 bits (86), Expect = 0.037
Identities = 19/43 (44%), Positives = 29/43 (67%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
Y G+Y T S +++HR R+ ++ AGVD+LALET+P +E
Sbjct: 126 YTGAYQLTPS--AYQDFHRERLALIMAAGVDVLALETMPRLDE 166
>UniRef50_Q6BZK6 Cluster: Debaryomyces hansenii chromosome A of
strain CBS767 of Debaryomyces hansenii; n=1;
Debaryomyces hansenii|Rep: Debaryomyces hansenii
chromosome A of strain CBS767 of Debaryomyces hansenii -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 351
Score = 59.7 bits (138), Expect = 2e-08
Identities = 33/90 (36%), Positives = 57/90 (63%), Gaps = 5/90 (5%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHL-GVTKEQGYELI-ARAVQLAKQARTLYLEEY- 172
H D++ +GA++I T+TYQAS G +E+ G+ + + +A++LA AR+ YLE
Sbjct: 61 HYDYMCSGANIITTSTYQASKRGLLEYAPGIENDDEVNAVYDKAIELAVDARSQYLENMG 120
Query: 173 --RDYVQNDDIPLIVGSVGPYGAHLHDGSD 256
+ + N +I I GS+GP+GA+L +G++
Sbjct: 121 KGMNTLTNKEI-FICGSIGPFGAYLANGAE 149
>UniRef50_Q8LAX0 Cluster: Homocysteine S-methyltransferase 3; n=30;
Magnoliophyta|Rep: Homocysteine S-methyltransferase 3 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 347
Score = 58.8 bits (136), Expect = 3e-08
Identities = 34/94 (36%), Positives = 55/94 (58%), Gaps = 9/94 (9%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEE---- 169
HLD+L +GA++IIT +YQA+++GFV G++ + L+ R+V++ +AR ++
Sbjct: 62 HLDYLESGANIIITASYQATIQGFVAK-GLSVGEAENLLRRSVEITYEAREIFYNRCTKG 120
Query: 170 -----YRDYVQNDDIPLIVGSVGPYGAHLHDGSD 256
Y I L+ SVG YGA+L DGS+
Sbjct: 121 SWDFAYAGKASRRPI-LVAASVGSYGAYLADGSE 153
Score = 50.4 bits (115), Expect = 1e-05
Identities = 20/39 (51%), Positives = 29/39 (74%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIP 372
Y G Y D+ S ET++++HR R+Q L ++G DL+A ETIP
Sbjct: 154 YSGIYGDSVSKETLKDFHRRRVQILAKSGADLIAFETIP 192
>UniRef50_Q1GBT8 Cluster: Homocysteine S-methyltransferase; n=2;
Lactobacillus delbrueckii subsp. bulgaricus|Rep:
Homocysteine S-methyltransferase - Lactobacillus
delbrueckii subsp. bulgaricus (strain ATCC 11842 /
DSM20081)
Length = 310
Score = 57.2 bits (132), Expect = 1e-07
Identities = 32/85 (37%), Positives = 53/85 (62%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H ++ +AGA + IT++YQAS+ F++H G++++ LI + +A +AR + E
Sbjct: 51 HQEYFKAGARVTITDSYQASLPAFMKH-GLSEDAARALIRESAAVAIKARDDF--EKETG 107
Query: 182 VQNDDIPLIVGSVGPYGAHLHDGSD 256
+ N + GSVGPYGA+L DGS+
Sbjct: 108 IHN----FVAGSVGPYGAYLADGSE 128
Score = 37.1 bits (82), Expect = 0.11
Identities = 21/43 (48%), Positives = 25/43 (58%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
Y G YA S E ++H PRI+ LV GVD LA+ET P E
Sbjct: 129 YRGDYA--LSHEEYVDFHAPRIEELVAGGVDCLAVETQPKLSE 169
>UniRef50_UPI000050FD2A Cluster: COG2040:
Homocysteine/selenocysteine methylase
(S-methylmethionine-dependent); n=1; Brevibacterium
linens BL2|Rep: COG2040: Homocysteine/selenocysteine
methylase (S-methylmethionine-dependent) -
Brevibacterium linens BL2
Length = 308
Score = 55.2 bits (127), Expect = 4e-07
Identities = 34/85 (40%), Positives = 48/85 (56%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H DF+RAGA ++ T +YQA+ GF E + E+G LIAR+V++A A
Sbjct: 57 HADFIRAGAQIVTTASYQATPLGF-ERASIPAEEGLRLIARSVEIAAGAGD--------- 106
Query: 182 VQNDDIPLIVGSVGPYGAHLHDGSD 256
L+ GSVGPYGA L +G++
Sbjct: 107 ------ALVAGSVGPYGAALGNGAE 125
Score = 43.2 bits (97), Expect = 0.002
Identities = 23/43 (53%), Positives = 26/43 (60%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
Y G Y S E +HRPRI+ALV AG DLLA+ET P E
Sbjct: 126 YTGDYH--LSDEEFAAFHRPRIEALVNAGADLLAIETQPSLSE 166
>UniRef50_Q59QD2 Cluster: Putative uncharacterized protein SAM4;
n=1; Candida albicans|Rep: Putative uncharacterized
protein SAM4 - Candida albicans (Yeast)
Length = 311
Score = 53.6 bits (123), Expect = 1e-06
Identities = 32/85 (37%), Positives = 47/85 (55%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
HLD++ GAD+IIT+TYQ S +++G +Q L A+ +AK A + RD
Sbjct: 57 HLDYINVGADMIITSTYQTSYASLHKYIGYDMDQAIALWNSALNVAKNA---VKKSGRDD 113
Query: 182 VQNDDIPLIVGSVGPYGAHLHDGSD 256
V +I GS+GPY L +GS+
Sbjct: 114 V------IIAGSIGPYATLLANGSE 132
Score = 33.9 bits (74), Expect = 1.1
Identities = 15/43 (34%), Positives = 24/43 (55%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
Y+G Y T E + E+H P + + VD++ +ETIP +E
Sbjct: 133 YNGDYQGVTD-EELIEYHTPLFEFYENSDVDIICIETIPSFQE 174
>UniRef50_Q7D740 Cluster: Homocysteine S-methyltransferase; n=14;
Actinomycetales|Rep: Homocysteine S-methyltransferase -
Mycobacterium tuberculosis
Length = 302
Score = 51.6 bits (118), Expect = 5e-06
Identities = 34/85 (40%), Positives = 46/85 (54%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H + RAGA + T +YQAS EGF G+ + L+ R+V+LA+ A RD
Sbjct: 47 HTAYFRAGAQIATTASYQASFEGFAAR-GIGHDDATVLLRRSVELAQAA--------RDE 97
Query: 182 VQNDDIPLIVGSVGPYGAHLHDGSD 256
V + + SVGPYGA L DGS+
Sbjct: 98 VGVGGLS-VAASVGPYGAALADGSE 121
Score = 46.0 bits (104), Expect = 2e-04
Identities = 20/43 (46%), Positives = 29/43 (67%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
Y G Y S+ + +WH PR++ LV+AG D+LAL+TIP +E
Sbjct: 122 YRGCYG--LSVAALMKWHLPRLEVLVDAGADMLALKTIPDIDE 162
>UniRef50_A3TGH3 Cluster: Homocysteine methyltransferase; n=1;
Janibacter sp. HTCC2649|Rep: Homocysteine
methyltransferase - Janibacter sp. HTCC2649
Length = 305
Score = 51.6 bits (118), Expect = 5e-06
Identities = 32/85 (37%), Positives = 49/85 (57%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H F+ AGA+++I+ +YQAS G+V G+T+E+ + +++LA+Q
Sbjct: 61 HRTFVDAGAEIVISASYQASHAGYVA-AGLTEEECDADLDASIELARQGA---------- 109
Query: 182 VQNDDIPLIVGSVGPYGAHLHDGSD 256
D L+ SVGPYGAHL DGS+
Sbjct: 110 ---DGRALVAASVGPYGAHLADGSE 131
Score = 37.1 bits (82), Expect = 0.11
Identities = 15/27 (55%), Positives = 22/27 (81%)
Frame = +1
Query: 292 TMREWHRPRIQALVEAGVDLLALETIP 372
T+RE+H R++ L+ AG DL+A+ETIP
Sbjct: 142 TLREFHSRRLERLIAAGPDLVAVETIP 168
>UniRef50_A5CB34 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 347
Score = 51.6 bits (118), Expect = 5e-06
Identities = 19/39 (48%), Positives = 29/39 (74%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIP 372
Y G Y D ++ET++++HR R+Q L +AG DL+A ET+P
Sbjct: 193 YSGIYGDEITVETLKDFHRRRVQILADAGADLIAFETVP 231
Score = 48.8 bits (111), Expect = 3e-05
Identities = 36/103 (34%), Positives = 55/103 (53%), Gaps = 18/103 (17%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQA-SVEGFVEHL---GVTKEQGYE-----LIARAVQLAKQART 154
HLD+L AGAD+IIT +YQ S +V L G+ E E + ++V++A +AR
Sbjct: 90 HLDYLEAGADIIITASYQVNSAYIYVNRLLFRGLKLEASLEEKVKPCLGKSVEIACEARK 149
Query: 155 LYLEEYRDYVQNDDIP---------LIVGSVGPYGAHLHDGSD 256
+Y + ++ +D L+ SVG YGA+L DGS+
Sbjct: 150 MYYDRCIEFACDDXEDGRILKHRPILVAASVGSYGAYLADGSE 192
>UniRef50_Q0BQM8 Cluster: Homocysteine S-methyltransferase; n=1;
Granulibacter bethesdensis CGDNIH1|Rep: Homocysteine
S-methyltransferase - Granulobacter bethesdensis (strain
ATCC BAA-1260 / CGDNIH1)
Length = 313
Score = 50.0 bits (114), Expect = 2e-05
Identities = 31/86 (36%), Positives = 49/86 (56%), Gaps = 1/86 (1%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQART-LYLEEYRD 178
H +L AGAD I T +YQ S+ G ++ G+++ + ++A A +LA R ++
Sbjct: 53 HRAYLEAGADCIETASYQLSLPG-LQRRGLSRGRAMSVLADAARLACSVRDDVWAGLPAA 111
Query: 179 YVQNDDIPLIVGSVGPYGAHLHDGSD 256
+N PL+ GS+GPYGA DGS+
Sbjct: 112 QRRNRIRPLVAGSLGPYGACQADGSE 137
Score = 35.1 bits (77), Expect = 0.46
Identities = 18/43 (41%), Positives = 25/43 (58%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
Y G YA + S +H PR++AL G DL+A ET+P +E
Sbjct: 138 YTGRYALSRS--QYLAFHAPRMRALAAGGADLIACETVPHLDE 178
>UniRef50_Q49V93 Cluster: Putative homocysteine S-methyltransferase;
n=1; Staphylococcus saprophyticus subsp. saprophyticus
ATCC 15305|Rep: Putative homocysteine
S-methyltransferase - Staphylococcus saprophyticus
subsp. saprophyticus (strain ATCC 15305 /DSM 20229)
Length = 301
Score = 49.6 bits (113), Expect = 2e-05
Identities = 32/85 (37%), Positives = 47/85 (55%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H F GAD+++T+TYQAS + F + +G+ + +L AV +A T
Sbjct: 51 HQAFTDVGADILLTSTYQASYQTFSD-IGMKATEIDQLYNTAVNQIMEATT--------- 100
Query: 182 VQNDDIPLIVGSVGPYGAHLHDGSD 256
D +IVGS+GPYGA+L DGS+
Sbjct: 101 ----DTQVIVGSLGPYGAYLSDGSE 121
Score = 33.5 bits (73), Expect = 1.4
Identities = 17/43 (39%), Positives = 26/43 (60%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIPCXEE 384
Y G+Y S E ++H+ RI+ALV+ G++ ET+P EE
Sbjct: 122 YTGAY--DLSKEDYFQFHKTRIEALVKRGINDFVFETVPNFEE 162
>UniRef50_A5DTG6 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 326
Score = 49.6 bits (113), Expect = 2e-05
Identities = 29/91 (31%), Positives = 51/91 (56%), Gaps = 6/91 (6%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H ++ AG+++I T+TYQ S + +H ++ EQ E+ R++ L + A L ++E Y
Sbjct: 54 HEMYIGAGSEVIFTSTYQLSYDSLRKHTTLSDEQILEVWQRSIDLVRAA-ALSIDETARY 112
Query: 182 VQNDDIP------LIVGSVGPYGAHLHDGSD 256
+ + I GS+GPY A+L +GS+
Sbjct: 113 TKEKESRGEPGKVHIAGSIGPYAAYLANGSE 143
Score = 33.1 bits (72), Expect = 1.9
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVE-AGVDLLALETIPCXEE 384
Y G Y + T E + +H P ++ E VDL+A ETIP +E
Sbjct: 144 YTGDYGNVTD-EQLEAFHTPMLEFFTENEAVDLIAFETIPNFQE 186
>UniRef50_UPI0000E4900F Cluster: PREDICTED: similar to
5-methyltetrahydrofolate:homocysteine methyltransferase;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to 5-methyltetrahydrofolate:homocysteine
methyltransferase - Strongylocentrotus purpuratus
Length = 172
Score = 48.0 bits (109), Expect = 6e-05
Identities = 20/30 (66%), Positives = 25/30 (83%)
Frame = +1
Query: 295 MREWHRPRIQALVEAGVDLLALETIPCXEE 384
+++WHRPRIQALV+ VDLLA+ETIP E
Sbjct: 6 LKQWHRPRIQALVDGKVDLLAIETIPSIVE 35
>UniRef50_A3LQC9 Cluster: AdoMet-homocysteine methyltransferase;
n=1; Pichia stipitis|Rep: AdoMet-homocysteine
methyltransferase - Pichia stipitis (Yeast)
Length = 337
Score = 46.0 bits (104), Expect = 2e-04
Identities = 27/87 (31%), Positives = 47/87 (54%), Gaps = 2/87 (2%)
Frame = +2
Query: 2 HLDFL-RAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRD 178
H ++L +A D +I++TYQ S EH + EQ + +++ + + A + +YR
Sbjct: 57 HYNYLEQADVDALISSTYQISYPSLKEHTDLDDEQIRGIWKKSIDVVEDA----ILQYRS 112
Query: 179 YVQNDDIPL-IVGSVGPYGAHLHDGSD 256
N + I+GS+GPY +L DGS+
Sbjct: 113 KNSNSKKKIYIIGSIGPYATYLADGSE 139
>UniRef50_Q4PDM6 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 448
Score = 45.6 bits (103), Expect = 3e-04
Identities = 32/88 (36%), Positives = 49/88 (55%), Gaps = 3/88 (3%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLY-LEEYRD 178
HL +L+AGA +I T TYQAS+E F + L+++AV LA A + + +
Sbjct: 69 HLHYLQAGAGIIGTATYQASLESFA-RANYDQVSASHLMSKAVDLACDALHAHNISNNKV 127
Query: 179 YVQN--DDIPLIVGSVGPYGAHLHDGSD 256
V + PL+ S+GPYGA L +G++
Sbjct: 128 GVASAASARPLLSLSLGPYGAMLSNGAE 155
>UniRef50_A6G853 Cluster: Homocysteine methyltransferase; n=1;
Plesiocystis pacifica SIR-1|Rep: Homocysteine
methyltransferase - Plesiocystis pacifica SIR-1
Length = 325
Score = 44.4 bits (100), Expect = 8e-04
Identities = 31/85 (36%), Positives = 47/85 (55%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H + AGAD++ T +YQAS+ G + G+++ + L+ +V L + A +E
Sbjct: 59 HRRWRDAGADILATASYQASLPG-LRAKGLSEARAKALLRESVTLTRAAA----DE---- 109
Query: 182 VQNDDIPLIVGSVGPYGAHLHDGSD 256
N PLI SVG YGA+L DGS+
Sbjct: 110 -ANAPRPLIAASVGSYGAYLADGSE 133
Score = 39.5 bits (88), Expect = 0.021
Identities = 18/39 (46%), Positives = 24/39 (61%)
Frame = +1
Query: 256 YDGSYADTTSIETMREWHRPRIQALVEAGVDLLALETIP 372
Y G Y S+E + ++HRPR+ L AG DL+A ET P
Sbjct: 134 YRGGYG--LSVEALADFHRPRLLELAAAGPDLIAFETFP 170
>UniRef50_Q5KA93 Cluster: Homocysteine S-methyltransferase,
putative; n=1; Filobasidiella neoformans|Rep:
Homocysteine S-methyltransferase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 381
Score = 42.3 bits (95), Expect = 0.003
Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 3/96 (3%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQ---ARTLYLEEY 172
H +++ GADL+ T TYQ + + +HL +E+ ++ V+L + + EE+
Sbjct: 44 HEGYVQGGADLVETATYQLTPQNLCDHLHCPREEAECILCSGVKLVASCIASCSSRNEEH 103
Query: 173 RDYVQNDDIPLIVGSVGPYGAHLHDGSDTMAVMQTP 280
+ + +V S GPYG+ L G + + P
Sbjct: 104 NTKSKGGNKSKVVLSFGPYGSTLQPGQEYGGIYPPP 139
>UniRef50_A5DCB0 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 313
Score = 41.5 bits (93), Expect = 0.005
Identities = 26/80 (32%), Positives = 39/80 (48%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H FL AG D++ T+TYQ S ++ T Q EL A++V + QA + + R
Sbjct: 50 HKSFLEAGCDIVTTSTYQISRASLKKYTDFTDAQIEELWAKSVDVCWQACKFHESKAR-- 107
Query: 182 VQNDDIPLIVGSVGPYGAHL 241
+ G++GPYG L
Sbjct: 108 --------VCGAIGPYGGFL 119
>UniRef50_Q6C0D6 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 348
Score = 40.3 bits (90), Expect = 0.012
Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTK-EQGYELIARAVQLAKQARTLYLEEYRD 178
H D++ AGAD++ + +YQAS+EG ++ V + + ++ ++ QL ++A T + +
Sbjct: 83 HKDYVVAGADIVTSASYQASLEGTIKAGAVQRWPEALWMLRKSEQLVRKAVTEAKVKRK- 141
Query: 179 YVQNDDIPLIVGSVGPYGAHLHDGSD 256
L+ SVGP+GA L G +
Sbjct: 142 -------VLLAASVGPFGAWLGGGQE 160
>UniRef50_Q748T0 Cluster: 5-methyltetrahydrofolate-homocysteine
methyltransferase, truncation; n=8;
Desulfuromonadales|Rep:
5-methyltetrahydrofolate-homocysteine methyltransferase,
truncation - Geobacter sulfurreducens
Length = 804
Score = 39.1 bits (87), Expect = 0.028
Identities = 20/48 (41%), Positives = 34/48 (70%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQ 145
H ++L AGAD+I+TNT+ S +EH G+ +++ E+ ARAV +A++
Sbjct: 50 HREYLDAGADIIVTNTFGGS-RAKLEHYGL-QDRVAEINARAVAIARE 95
>UniRef50_A5K8K1 Cluster: Putative uncharacterized protein; n=1;
Plasmodium vivax|Rep: Putative uncharacterized protein -
Plasmodium vivax
Length = 508
Score = 39.1 bits (87), Expect = 0.028
Identities = 21/68 (30%), Positives = 38/68 (55%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
HL +L AG ++I TNT+Q ++ E G++ + G ++ R + +A +A L Y
Sbjct: 46 HLSYLLAGCNVISTNTFQVNLHSLQEK-GISVQDGEGIVDRYIDIAHRA----LLRYEGI 100
Query: 182 VQNDDIPL 205
+++D PL
Sbjct: 101 KRSEDFPL 108
>UniRef50_Q1DSS3 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 1785
Score = 38.3 bits (85), Expect = 0.049
Identities = 26/87 (29%), Positives = 39/87 (44%), Gaps = 9/87 (10%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGV---------TKEQGYELIARAVQLAKQART 154
H ++ AGAD+++T TYQAS EGF V E+ R + + R+
Sbjct: 51 HRSYVDAGADIVLTATYQASFEGFARTAIVPANVPADHKQDERDGHATYRPMDATRYMRS 110
Query: 155 LYLEEYRDYVQNDDIPLIVGSVGPYGA 235
Y + + P + S+GPYGA
Sbjct: 111 AIPLAYSSFNFSSKPPRVALSLGPYGA 137
>UniRef50_Q08985 Cluster: Homocysteine S-methyltransferase 2; n=9;
Saccharomycetaceae|Rep: Homocysteine S-methyltransferase
2 - Saccharomyces cerevisiae (Baker's yeast)
Length = 325
Score = 36.7 bits (81), Expect = 0.15
Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Frame = +2
Query: 8 DFLRAGADLIITNTYQASVEGFVEHLGV-TKEQGYELIARAVQLAKQARTLYLEEYRDYV 184
DFL AGA++++T TYQ S + E+ + T + L+ R V + R+ +
Sbjct: 68 DFLNAGAEILMTTTYQTSYKSVSENTPIRTLSEYNNLLNRIVDFS-----------RNCI 116
Query: 185 QNDDIPLIVGSVGPYGAHL 241
D ++G +GP+GAH+
Sbjct: 117 GED--KYLIGCIGPWGAHI 133
>UniRef50_Q2JJL4 Cluster: Methionine synthase; n=25;
Cyanobacteria|Rep: Methionine synthase - Synechococcus
sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria
bacteriumYellowstone B-Prime)
Length = 1224
Score = 35.9 bits (79), Expect = 0.26
Identities = 24/75 (32%), Positives = 38/75 (50%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H FL GAD++ TNT+ A+ E+ G+ E+ YEL A +LAK+ ++
Sbjct: 58 HRGFLEVGADVVETNTFGATSIVLAEY-GI-PEKAYELNVAAARLAKRVAA-------EF 108
Query: 182 VQNDDIPLIVGSVGP 226
+ + GS+GP
Sbjct: 109 ATPEKPRFVAGSIGP 123
>UniRef50_Q753B4 Cluster: AFR410Wp; n=1; Eremothecium gossypii|Rep:
AFR410Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 370
Score = 35.9 bits (79), Expect = 0.26
Identities = 29/84 (34%), Positives = 41/84 (48%), Gaps = 1/84 (1%)
Frame = +2
Query: 8 DFLRAGADLIITNTYQASVEGFVEHLG-VTKEQGYELIARAVQLAKQARTLYLEEYRDYV 184
+F AG+ I T TYQAS V++ G V+ YE Q+ ++ RDY
Sbjct: 104 EFRAAGSRGISTLTYQASFHSMVKYSGSVSSRADYEKFLE--QVVDFTYRECVDPARDY- 160
Query: 185 QNDDIPLIVGSVGPYGAHLHDGSD 256
I+GSVGPY A L +G++
Sbjct: 161 -------IIGSVGPYAAFLCNGAE 177
>UniRef50_A1SWN6 Cluster: Homocysteine S-methyltransferase; n=2;
Gammaproteobacteria|Rep: Homocysteine
S-methyltransferase - Psychromonas ingrahamii (strain
37)
Length = 310
Score = 35.5 bits (78), Expect = 0.35
Identities = 27/77 (35%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTK--EQGYELIARAVQLAKQARTLYLEEYR 175
H F+ AGA++I TNTY ++ F H+G + EQG +LI A +LA++ ++E
Sbjct: 55 HKSFIEAGAEVITTNTY--ALVPF--HIGEKRFNEQGADLIKLAARLAREC----VKENS 106
Query: 176 DYVQNDDIPLIVGSVGP 226
+ IP ++GS P
Sbjct: 107 AVLVAGCIPPVLGSYRP 123
>UniRef50_Q2TXK9 Cluster: Predicted protein; n=2;
Trichocomaceae|Rep: Predicted protein - Aspergillus
oryzae
Length = 376
Score = 35.5 bits (78), Expect = 0.35
Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 1/50 (2%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGF-VEHLGVTKEQGYELIARAVQLAKQA 148
H F GAD+I+T TYQ S EGF + T + + A+ LA++A
Sbjct: 51 HKAFATVGADIILTATYQTSFEGFTLTDPRYTADDAAHFMRSAIPLARRA 100
>UniRef50_A3UPV1 Cluster: Homocysteine S-methyltransferase family
protein; n=6; Vibrionales|Rep: Homocysteine
S-methyltransferase family protein - Vibrio splendidus
12B01
Length = 299
Score = 34.3 bits (75), Expect = 0.81
Identities = 21/49 (42%), Positives = 35/49 (71%), Gaps = 2/49 (4%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLG--VTKEQGYELIARAVQLAK 142
H +F+ AGA+++ITN+Y A V HLG + +++G+EL A++ +LAK
Sbjct: 43 HQNFVDAGAEILITNSY-ACVP---FHLGEELFEQRGFELAAQSGELAK 87
>UniRef50_Q4WFR2 Cluster: Homocysteine S-methyltransferase,
putative; n=3; Trichocomaceae|Rep: Homocysteine
S-methyltransferase, putative - Aspergillus fumigatus
(Sartorya fumigata)
Length = 313
Score = 34.3 bits (75), Expect = 0.81
Identities = 15/38 (39%), Positives = 27/38 (71%), Gaps = 3/38 (7%)
Frame = +1
Query: 265 SYADTTSIETM---REWHRPRIQALVEAGVDLLALETI 369
+Y DT+ + T+ RE +R +++ L +AGVD+LA+ T+
Sbjct: 129 AYVDTSELITLEDAREGYREQVEVLADAGVDMLAIMTV 166
>UniRef50_A3JFK5 Cluster: Putative uncharacterized protein; n=1;
Marinobacter sp. ELB17|Rep: Putative uncharacterized
protein - Marinobacter sp. ELB17
Length = 303
Score = 33.9 bits (74), Expect = 1.1
Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 5/49 (10%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASV-----EGFVEHLGVTKEQGYELIARAVQ 133
H DF+RAGA + NTY A+ G +E L + +EL+ +AV+
Sbjct: 43 HSDFIRAGAKTLSLNTYAATPSRLLRHGQLEQLAAIHQNAFELLGQAVK 91
>UniRef50_Q8I585 Cluster: Putative uncharacterized protein; n=2;
Plasmodium|Rep: Putative uncharacterized protein -
Plasmodium falciparum (isolate 3D7)
Length = 581
Score = 33.9 bits (74), Expect = 1.1
Identities = 21/70 (30%), Positives = 39/70 (55%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
HL +L G ++I TNT+Q ++ F + LG+ + G E++ + + +A + Y E R
Sbjct: 49 HLSYLLGGCNIIGTNTFQVNLYSF-KKLGI--DNGEEILNKYINIAYNSLLKYEEIKRK- 104
Query: 182 VQNDDIPLIV 211
DDI +++
Sbjct: 105 -SKDDINVLL 113
>UniRef50_Q2S678 Cluster: Vitamin B12-dependent methionine synthase
family protein; n=1; Salinibacter ruber DSM 13855|Rep:
Vitamin B12-dependent methionine synthase family protein
- Salinibacter ruber (strain DSM 13855)
Length = 320
Score = 33.5 bits (73), Expect = 1.4
Identities = 28/75 (37%), Positives = 38/75 (50%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H ++LRAGAD+I TNTY E E G+ + L A +LA++AR RD
Sbjct: 52 HEEYLRAGADVITTNTYATPPERLSE-AGL-DGRAEALNREAGRLAERARAAV---GRDA 106
Query: 182 VQNDDIPLIVGSVGP 226
+ +P I GS P
Sbjct: 107 LIAGSLPPIRGSYRP 121
>UniRef50_A7C1C8 Cluster: 5-methyltetrahydrofolate--homocysteine
S-methyltransferase; n=1; Beggiatoa sp. PS|Rep:
5-methyltetrahydrofolate--homocysteine
S-methyltransferase - Beggiatoa sp. PS
Length = 157
Score = 33.5 bits (73), Expect = 1.4
Identities = 18/49 (36%), Positives = 28/49 (57%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQA 148
H +L AGAD+I TNT+ A+ ++ +E YEL +LA++A
Sbjct: 67 HTQYLEAGADIIETNTFNATRIAMADYR--MEELVYELNVAGAKLAREA 113
>UniRef50_Q30ZI4 Cluster: Vitamin B12-dependent methionine synthase
family protein; n=3; Desulfovibrio|Rep: Vitamin
B12-dependent methionine synthase family protein -
Desulfovibrio desulfuricans (strain G20)
Length = 841
Score = 33.1 bits (72), Expect = 1.9
Identities = 21/55 (38%), Positives = 31/55 (56%), Gaps = 1/55 (1%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQA-RTLYL 163
HLD+ RAGAD++ TNT+ + E + V E E+ A A QA RT+++
Sbjct: 81 HLDYARAGADVLTTNTFGGTRLKLPEGMNVV-EFNREMARAAKAAAGQAGRTVFV 134
>UniRef50_Q4Y025 Cluster: Putative uncharacterized protein; n=4;
Plasmodium (Vinckeia)|Rep: Putative uncharacterized
protein - Plasmodium chabaudi
Length = 504
Score = 33.1 bits (72), Expect = 1.9
Identities = 16/53 (30%), Positives = 31/53 (58%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLY 160
HL +L +G+++I TNTYQ ++ + ++ E G E+I + +A ++ Y
Sbjct: 47 HLSYLLSGSNIITTNTYQVNLH--FKRNNISIENGKEIIDTYIDIAYESCEKY 97
>UniRef50_Q7SFT2 Cluster: Putative uncharacterized protein
NCU00799.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU00799.1 - Neurospora crassa
Length = 361
Score = 33.1 bits (72), Expect = 1.9
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 12/61 (19%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFV------------EHLGVTKEQGYELIARAVQLAKQ 145
H F +AGA++I T TYQ S+ GF E G+ KE+ ++RAV LA
Sbjct: 50 HEAFKQAGANIISTATYQISINGFAATKAPRSGTVDEEREGIEKEEIPRFLSRAVVLAAN 109
Query: 146 A 148
A
Sbjct: 110 A 110
>UniRef50_A4J6L9 Cluster: Homocysteine S-methyltransferase; n=1;
Desulfotomaculum reducens MI-1|Rep: Homocysteine
S-methyltransferase - Desulfotomaculum reducens MI-1
Length = 800
Score = 32.7 bits (71), Expect = 2.5
Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVE-HLGVTKEQGYELIARAVQLAKQARTLYLEEYRD 178
H +L AGAD+I TNT+ A + HLG +Q E+ AV+LAK+ Y
Sbjct: 48 HKLYLEAGADIITTNTFGAIQLKLADYHLG---DQVKEINQAAVKLAKEVAQPY------ 98
Query: 179 YVQNDDIPLIVGSVGPYGAHL 241
++ GSVGP G L
Sbjct: 99 ------GAMVAGSVGPLGKFL 113
>UniRef50_A3XRC5 Cluster: Oxidoreductase; n=13; Bacteroidetes|Rep:
Oxidoreductase - Leeuwenhoekiella blandensis MED217
Length = 382
Score = 32.7 bits (71), Expect = 2.5
Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 3/70 (4%)
Frame = +2
Query: 14 LRAGADLIITNTYQASVEGFVEHLGVTKEQ---GYELIARAVQLAKQARTLYLEEYRDYV 184
+RA + TN + GF HLG+T+ Q L+ + + K T +L+E Y
Sbjct: 215 IRANSISFKTNKLFIATNGFAAHLGITQVQPARNQVLVTKPIADLKIKGTFHLDEGYTYF 274
Query: 185 QNDDIPLIVG 214
+N D +++G
Sbjct: 275 RNIDNRILLG 284
>UniRef50_A6S563 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 369
Score = 32.7 bits (71), Expect = 2.5
Identities = 13/21 (61%), Positives = 17/21 (80%)
Frame = +2
Query: 11 FLRAGADLIITNTYQASVEGF 73
F+ AGAD+++T TYQ S EGF
Sbjct: 56 FVDAGADILLTATYQTSYEGF 76
>UniRef50_A2R696 Cluster: Contig An15c0240, complete genome; n=6;
Pezizomycotina|Rep: Contig An15c0240, complete genome -
Aspergillus niger
Length = 353
Score = 32.7 bits (71), Expect = 2.5
Identities = 26/79 (32%), Positives = 37/79 (46%)
Frame = +2
Query: 20 AGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDI 199
A D+++T TYQ S EGF TK + +A RT L+ VQN
Sbjct: 56 AAVDVLLTATYQVSPEGFQR----TKTPSHPTGIPRESIAGYLRTA-LDVAGQAVQNTSA 110
Query: 200 PLIVGSVGPYGAHLHDGSD 256
+ + S+GPYGA + G +
Sbjct: 111 SVAL-SLGPYGACMIPGQE 128
>UniRef50_UPI0000DAE3F2 Cluster: hypothetical protein
Rgryl_01000241; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01000241 - Rickettsiella
grylli
Length = 342
Score = 32.3 bits (70), Expect = 3.3
Identities = 15/36 (41%), Positives = 19/36 (52%)
Frame = +1
Query: 217 CRTIWSSSSRRFRYDGSYADTTSIETMREWHRPRIQ 324
C T SS RY G Y+ T SI+ REW R ++
Sbjct: 285 CITGMSSVVHSIRYPGIYSSTHSIQPRREWQRNSVR 320
>UniRef50_Q0LM71 Cluster: Methylenetetrahydrofolate reductase; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep:
Methylenetetrahydrofolate reductase - Herpetosiphon
aurantiacus ATCC 23779
Length = 617
Score = 32.3 bits (70), Expect = 3.3
Identities = 26/80 (32%), Positives = 42/80 (52%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H ++ AGAD+I TNTY A+ +E G+ ++ ++ R ++LA++AR +
Sbjct: 50 HQSYIEAGADIIETNTYGAN-RFKLEPFGLA-DKVRQINHRGMKLAREAREI-------- 99
Query: 182 VQNDDIPLIVGSVGPYGAHL 241
LI G+VGP G L
Sbjct: 100 --AGTNTLIAGAVGPLGVLL 117
>UniRef50_Q01YW7 Cluster: Methionine synthase; n=2; Bacteria|Rep:
Methionine synthase - Solibacter usitatus (strain
Ellin6076)
Length = 1185
Score = 32.3 bits (70), Expect = 3.3
Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 1/87 (1%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H +L AGAD+I TNT+ + ++ +E+ YEL A +LA++ + +
Sbjct: 63 HRQYLEAGADIIETNTFGGTRIALADN--KLEERAYELNFAAAKLAREVADQFSTAAKP- 119
Query: 182 VQNDDIPLIVGSVGPYGAHLH-DGSDT 259
+ GS+GP L+ GS T
Sbjct: 120 ------RFVAGSIGPTNKDLNITGSTT 140
>UniRef50_A6CD85 Cluster: Fructose-1-phosphate kinase and related
fructose-6-phosphate kinase; n=1; Planctomyces maris DSM
8797|Rep: Fructose-1-phosphate kinase and related
fructose-6-phosphate kinase - Planctomyces maris DSM
8797
Length = 307
Score = 32.3 bits (70), Expect = 3.3
Identities = 16/45 (35%), Positives = 27/45 (60%)
Frame = +2
Query: 101 QGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLIVGSVGPYGA 235
Q EL+ A ++ + + + +EYR YV + DI ++ GS+ P GA
Sbjct: 100 QTTELVENATAVSAEEVSAFADEYRKYVSSADIVVLTGSL-PTGA 143
>UniRef50_A5FJM4 Cluster: Glucan endo-1,6-beta-glucosidase; n=2;
Bacteria|Rep: Glucan endo-1,6-beta-glucosidase -
Flavobacterium johnsoniae UW101
Length = 474
Score = 32.3 bits (70), Expect = 3.3
Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Frame = +2
Query: 119 ARAVQLAKQARTLYLEEYRDYVQN-DDIPLIVGSVGPYGAHLHDGSDTMAVMQTPRQ*RL 295
++A L + +Y + + Y+Q +I+ ++ P LH G++ +M +Q
Sbjct: 194 SKAGSLQPKYYEVYAQYFVKYIQAMKSHGIIIDAITPQNEPLHPGNNPSLLMLAEQQADF 253
Query: 296 CGNGIGPEFK 325
GN +GP FK
Sbjct: 254 VGNHLGPAFK 263
>UniRef50_A4R5G4 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 374
Score = 32.3 bits (70), Expect = 3.3
Identities = 13/22 (59%), Positives = 17/22 (77%)
Frame = +2
Query: 8 DFLRAGADLIITNTYQASVEGF 73
+F AGAD+++T TYQ SVE F
Sbjct: 48 EFAAAGADVLLTATYQVSVEAF 69
>UniRef50_Q9ZE64 Cluster: Putative uncharacterized protein RP083;
n=2; Rickettsia|Rep: Putative uncharacterized protein
RP083 - Rickettsia prowazekii
Length = 521
Score = 31.9 bits (69), Expect = 4.3
Identities = 17/50 (34%), Positives = 26/50 (52%)
Frame = +2
Query: 41 TNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQN 190
T YQ ++G + L + KE+G ELI +VQ K Y ++ + QN
Sbjct: 309 TMAYQKYLKGAEDQLALAKEKGKELIENSVQTFKIIPKKYQDDMNENWQN 358
>UniRef50_Q98KX0 Cluster: Mlr1281 protein; n=4; Proteobacteria|Rep:
Mlr1281 protein - Rhizobium loti (Mesorhizobium loti)
Length = 301
Score = 31.9 bits (69), Expect = 4.3
Identities = 18/49 (36%), Positives = 27/49 (55%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQA 148
H +F+RAGA +I NTY A+ E ++ L R ++LA+QA
Sbjct: 43 HAEFIRAGARVITINTYSATPERLARE--GAEDLFKPLQKRGIELARQA 89
>UniRef50_Q7M929 Cluster: S-METHYLTRANSFERASE; n=1; Wolinella
succinogenes|Rep: S-METHYLTRANSFERASE - Wolinella
succinogenes
Length = 1120
Score = 31.9 bits (69), Expect = 4.3
Identities = 17/49 (34%), Positives = 29/49 (59%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQA 148
H +L AGAD++ +NT+ A + +E G+ + YE+ Q+AK+A
Sbjct: 57 HRSYLEAGADILKSNTFGA-LPWVLEEYGI-GGRAYEMAFAGAQIAKEA 103
>UniRef50_Q5FP86 Cluster: 5-Methyltetrahydrofolate-S-homocysteine
methyltransferase; n=9; cellular organisms|Rep:
5-Methyltetrahydrofolate-S-homocysteine
methyltransferase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 1168
Score = 31.9 bits (69), Expect = 4.3
Identities = 22/75 (29%), Positives = 38/75 (50%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H + AGAD++ TNT+ S+ E G+ +++ E+ A LA++A + + Y
Sbjct: 59 HRGYFEAGADMVETNTFGGSIVTLAE-FGL-QDRTREINRTAATLAREAAETFADGRHRY 116
Query: 182 VQNDDIPLIVGSVGP 226
V +GS+GP
Sbjct: 117 V--------MGSIGP 123
>UniRef50_Q0LZ78 Cluster: Putative uncharacterized protein; n=1;
Caulobacter sp. K31|Rep: Putative uncharacterized
protein - Caulobacter sp. K31
Length = 415
Score = 31.9 bits (69), Expect = 4.3
Identities = 26/76 (34%), Positives = 34/76 (44%)
Frame = +2
Query: 29 DLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDDIPLI 208
DL +N + V GF EHL E G + L+ QA T E YRD V + + LI
Sbjct: 198 DLEASNVDRRFVAGF-EHLKEVSETGEAVAVGLAHLSLQAAT---ETYRDEVPDATLSLI 253
Query: 209 VGSVGPYGAHLHDGSD 256
G GA+ + D
Sbjct: 254 SGLGVAVGAYTNQFED 269
>UniRef50_A7AL74 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 1231
Score = 31.9 bits (69), Expect = 4.3
Identities = 23/75 (30%), Positives = 39/75 (52%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H +L AGAD+ TNT+ A+ +E G+ + Q + A +LA++ +++E+ D
Sbjct: 66 HRQYLDAGADIFATNTFNANAIS-MEDYGM-QGQVRNINLAAGKLAREVADGFMKEHPDR 123
Query: 182 VQNDDIPLIVGSVGP 226
+ GSVGP
Sbjct: 124 T-----IFVAGSVGP 133
>UniRef50_A4B5J7 Cluster: Homocysteine S-methyltransferase family
protein; n=1; Alteromonas macleodii 'Deep ecotype'|Rep:
Homocysteine S-methyltransferase family protein -
Alteromonas macleodii 'Deep ecotype'
Length = 305
Score = 31.9 bits (69), Expect = 4.3
Identities = 21/51 (41%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLG--VTKEQGYELIARAVQLAKQA 148
H FL AGA +I TNTY ++ F H+G EQ ++L A +LA+ A
Sbjct: 47 HTHFLNAGATVITTNTY--ALVPF--HIGEQTFNEQAFKLAETAAKLARDA 93
>UniRef50_Q4GZ92 Cluster: Homocysteine S-methyltransferase,
putative; n=1; Trypanosoma brucei|Rep: Homocysteine
S-methyltransferase, putative - Trypanosoma brucei
Length = 433
Score = 31.9 bits (69), Expect = 4.3
Identities = 15/34 (44%), Positives = 20/34 (58%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQ 103
H +L GAD+I+TNTYQ G + GVT +
Sbjct: 65 HKSYLDVGADVILTNTYQMHAAGCAQ-AGVTMNE 97
>UniRef50_A7TSR2 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 323
Score = 31.9 bits (69), Expect = 4.3
Identities = 22/78 (28%), Positives = 39/78 (50%)
Frame = +2
Query: 8 DFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQ 187
D++ +G+ ++ T TYQ S H V +GY+ + R + T + R +
Sbjct: 68 DYITSGSRILSTITYQTSFALISTHTEVKTIEGYKQLIRNI-------TSFC---RSAIG 117
Query: 188 NDDIPLIVGSVGPYGAHL 241
D+ ++GS+GP+GA L
Sbjct: 118 EDN--YLIGSIGPFGARL 133
>UniRef50_P43822 Cluster: Glycyl-tRNA synthetase beta chain; n=17;
Gammaproteobacteria|Rep: Glycyl-tRNA synthetase beta
chain - Haemophilus influenzae
Length = 688
Score = 31.9 bits (69), Expect = 4.3
Identities = 16/48 (33%), Positives = 27/48 (56%)
Frame = -3
Query: 185 ERSHGILPDRGCGLV*RAELRGLLIHNLVLSLLPDALRSLPLKLGMYW 42
E++ I D+G L+ RA++ G NL+ ++ +AL LP+ M W
Sbjct: 103 EQAERIATDKGEWLIHRAKIEGQPTKNLLNDIVANALAKLPIPKPMRW 150
>UniRef50_Q9KCE2 Cluster: Methylenetetrahydrofolate reductase; n=60;
Bacilli|Rep: Methylenetetrahydrofolate reductase -
Bacillus halodurans
Length = 618
Score = 31.5 bits (68), Expect = 5.7
Identities = 18/49 (36%), Positives = 30/49 (61%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQA 148
H+ ++ AGAD+I TNTY A+ ++ +Q E+ AV+LA++A
Sbjct: 47 HVAYVEAGADVIQTNTYAANRMKLAKY--QLDDQVLEINRAAVRLARKA 93
>UniRef50_Q2W1T1 Cluster: ABC-type branched-chain amino acid
transport systems, periplasmic component; n=2;
Magnetospirillum|Rep: ABC-type branched-chain amino acid
transport systems, periplasmic component -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 455
Score = 31.5 bits (68), Expect = 5.7
Identities = 13/38 (34%), Positives = 20/38 (52%)
Frame = +1
Query: 241 SRRFRYDGSYADTTSIETMREWHRPRIQALVEAGVDLL 354
+R + G D I + W RP + A+ EAG+D+L
Sbjct: 236 AREYAVSGLKGDVPLIGVWQGWERPMLPAMTEAGMDVL 273
>UniRef50_A6QBA6 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=1; Sulfurovum sp. NBC37-1|Rep:
5-methyltetrahydrofolate--homocysteine methyltransferase
- Sulfurovum sp. (strain NBC37-1)
Length = 1169
Score = 31.5 bits (68), Expect = 5.7
Identities = 22/75 (29%), Positives = 37/75 (49%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H + AGADLI TNT+ ++ ++ Y++ RA +L+K+ L E +Y
Sbjct: 63 HKRYAMAGADLIKTNTF-GTMPWVLDE--------YQMGERAYELSKKGAELVKEICAEY 113
Query: 182 VQNDDIPLIVGSVGP 226
++GS+GP
Sbjct: 114 STKISPKFVLGSIGP 128
>UniRef50_A6PRW5 Cluster: Methylenetetrahydrofolate reductase; n=1;
Victivallis vadensis ATCC BAA-548|Rep:
Methylenetetrahydrofolate reductase - Victivallis
vadensis ATCC BAA-548
Length = 595
Score = 31.5 bits (68), Expect = 5.7
Identities = 19/50 (38%), Positives = 33/50 (66%), Gaps = 1/50 (2%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARA-VQLAKQA 148
H +L+AGA+++ TNTY A+ + G++++ E I RA V+LA++A
Sbjct: 39 HHQYLKAGAEVLTTNTYNANSRRLAK-FGLSEQT--EAINRAGVKLAREA 85
>UniRef50_Q4DI99 Cluster: Homocysteine S-methyltransferase,
putative; n=2; Trypanosoma cruzi|Rep: Homocysteine
S-methyltransferase, putative - Trypanosoma cruzi
Length = 410
Score = 31.5 bits (68), Expect = 5.7
Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 24/109 (22%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQ---------------- 133
H ++ AG D+++T TYQ EG +K EL+ RAVQ
Sbjct: 50 HRAYIDAGCDVLLTCTYQMHEEG----CAASKVTMCELVDRAVQAARHTMPQRKQKGLTE 105
Query: 134 --LAKQARTLYLEEYRDYVQN------DDIPLIVGSVGPYGAHLHDGSD 256
AK+ RT ++ +R + + + + L+ GS+GPYG+ L G +
Sbjct: 106 ESTAKERRTGGIDVFRYALSSIKDNGQERVVLLAGSLGPYGSSLPGGQE 154
>UniRef50_Q22V72 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 564
Score = 31.5 bits (68), Expect = 5.7
Identities = 11/34 (32%), Positives = 23/34 (67%)
Frame = +2
Query: 95 KEQGYELIARAVQLAKQARTLYLEEYRDYVQNDD 196
KEQG+ + R++ K ++L L+ Y++ ++ND+
Sbjct: 406 KEQGFNSLVRSISKLKNLQSLNLDLYKNNIENDE 439
>UniRef50_P57905 Cluster: Glycyl-tRNA synthetase beta chain; n=47;
Gammaproteobacteria|Rep: Glycyl-tRNA synthetase beta
chain - Pasteurella multocida
Length = 689
Score = 31.5 bits (68), Expect = 5.7
Identities = 16/48 (33%), Positives = 26/48 (54%)
Frame = -3
Query: 185 ERSHGILPDRGCGLV*RAELRGLLIHNLVLSLLPDALRSLPLKLGMYW 42
E++ + D+G LV RA + G NL+ ++ +AL LP+ M W
Sbjct: 103 EQAERVATDKGEWLVHRATIEGQPTKNLLKDMVANALAKLPIPKPMRW 150
>UniRef50_UPI0000E47473 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 176
Score = 31.1 bits (67), Expect = 7.5
Identities = 26/84 (30%), Positives = 37/84 (44%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H +FLRAGAD+I T TY A+ + K ++ +A L E
Sbjct: 59 HREFLRAGADVIQTFTYCATEDNLKMKNEHEKNSNDMKSVSVSEINHRACDLARE----- 113
Query: 182 VQNDDIPLIVGSVGPYGAHLHDGS 253
V N+ L+ GSV A+ DG+
Sbjct: 114 VANEGGALVAGSVSNVNAYRKDGA 137
>UniRef50_Q7VBY3 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=8; Cyanobacteria|Rep:
5-methyltetrahydrofolate--homocysteine methyltransferase
- Prochlorococcus marinus
Length = 1182
Score = 31.1 bits (67), Expect = 7.5
Identities = 22/75 (29%), Positives = 37/75 (49%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
H +L G D+I TNT+ A+ E+ +++ YE+ A +LAK +++
Sbjct: 60 HRSYLEVGCDVIETNTFGATSIVLEEY--NLQDKTYEINLEAARLAKGI-------VKEF 110
Query: 182 VQNDDIPLIVGSVGP 226
+D + GSVGP
Sbjct: 111 STDDKPRFVAGSVGP 125
>UniRef50_Q1IL23 Cluster: Methylenetetrahydrofolate reductase; n=2;
Acidobacteria|Rep: Methylenetetrahydrofolate reductase -
Acidobacteria bacterium (strain Ellin345)
Length = 617
Score = 31.1 bits (67), Expect = 7.5
Identities = 15/29 (51%), Positives = 21/29 (72%)
Frame = +1
Query: 280 TSIETMREWHRPRIQALVEAGVDLLALET 366
TS + R+ R +I+ LV++GVDLL LET
Sbjct: 121 TSRDEARDAFRDQIRVLVDSGVDLLILET 149
>UniRef50_A7HBZ7 Cluster: Homocysteine S-methyltransferase; n=2;
Anaeromyxobacter|Rep: Homocysteine S-methyltransferase -
Anaeromyxobacter sp. Fw109-5
Length = 280
Score = 31.1 bits (67), Expect = 7.5
Identities = 17/49 (34%), Positives = 28/49 (57%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQA 148
H D RAGA++++T T+ + + L + + EL A AV+LA+ A
Sbjct: 48 HADHARAGAEIVLTCTFNLAAPRLAQRLDPPRVE--ELAAIAVRLARGA 94
>UniRef50_A5Z6N8 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 393
Score = 31.1 bits (67), Expect = 7.5
Identities = 11/29 (37%), Positives = 22/29 (75%)
Frame = +2
Query: 32 LIITNTYQASVEGFVEHLGVTKEQGYELI 118
+++ + +Q SV+GF++ L K++GYEL+
Sbjct: 340 VLLHDIHQTSVDGFIKALPTLKKRGYELV 368
>UniRef50_A0NPW7 Cluster: Periplasmic glucan biosynthesis protein;
n=1; Stappia aggregata IAM 12614|Rep: Periplasmic glucan
biosynthesis protein - Stappia aggregata IAM 12614
Length = 513
Score = 31.1 bits (67), Expect = 7.5
Identities = 10/30 (33%), Positives = 19/30 (63%)
Frame = +3
Query: 147 PAPSIWKNTVTTFKMMTFHS*WVLSDHMEL 236
P S+WK+T + +++ FH W+ + +EL
Sbjct: 73 PERSVWKDTRSNYQLQAFHPGWLYKEPVEL 102
>UniRef50_Q2FRP4 Cluster: Pre-mRNA processing ribonucleoprotein,
binding region; n=1; Methanospirillum hungatei JF-1|Rep:
Pre-mRNA processing ribonucleoprotein, binding region -
Methanospirillum hungatei (strain JF-1 / DSM 864)
Length = 295
Score = 31.1 bits (67), Expect = 7.5
Identities = 13/44 (29%), Positives = 24/44 (54%)
Frame = +2
Query: 50 YQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDY 181
Y+ ++ +E L + Q +AR +Q +++RTL + RDY
Sbjct: 132 YERNISSLIESLAKDQTQPMSHLARNIQRFRESRTLISQNVRDY 175
>UniRef50_Q88X64 Cluster: Methylenetetrahydrofolate reductase; n=1;
Lactobacillus plantarum|Rep: Methylenetetrahydrofolate
reductase - Lactobacillus plantarum
Length = 618
Score = 30.7 bits (66), Expect = 9.9
Identities = 12/20 (60%), Positives = 16/20 (80%)
Frame = +2
Query: 2 HLDFLRAGADLIITNTYQAS 61
H ++RAGAD+I TNTY A+
Sbjct: 47 HRSYIRAGADIIQTNTYAAN 66
>UniRef50_A3XF15 Cluster: Secreted hemolysin-type calcium-binding
bacteriocin, putative; n=4; Roseobacter|Rep: Secreted
hemolysin-type calcium-binding bacteriocin, putative -
Roseobacter sp. MED193
Length = 3377
Score = 30.7 bits (66), Expect = 9.9
Identities = 21/80 (26%), Positives = 35/80 (43%)
Frame = +2
Query: 17 RAGADLIITNTYQASVEGFVEHLGVTKEQGYELIARAVQLAKQARTLYLEEYRDYVQNDD 196
RA ++ +T+ + H+ GY+ +L + AR L + EY+ V ND
Sbjct: 2622 RANENVGLTSMHTVWARNHNYHVDQLLASGYDADTPE-ELFQAARILNIGEYQQVVFNDF 2680
Query: 197 IPLIVGSVGPYGAHLHDGSD 256
++G + G H HD D
Sbjct: 2681 ADSLLGGLQGSGTHGHDKYD 2700
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 391,646,939
Number of Sequences: 1657284
Number of extensions: 7758927
Number of successful extensions: 19849
Number of sequences better than 10.0: 86
Number of HSP's better than 10.0 without gapping: 19418
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 19811
length of database: 575,637,011
effective HSP length: 91
effective length of database: 424,824,167
effective search space used: 15293670012
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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