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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= heS30371
         (646 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI00003BFA45 Cluster: PREDICTED: similar to Nidogen/en...    63   6e-09
UniRef50_UPI0000D55DA8 Cluster: PREDICTED: similar to CG12908-PA...    51   3e-05
UniRef50_UPI0000F1F8DC Cluster: PREDICTED: similar to Nidogen-1 ...    46   8e-04
UniRef50_A6QNS6 Cluster: NID1 protein; n=5; Euteleostomi|Rep: NI...    44   0.003
UniRef50_P14543 Cluster: Nidogen-1 precursor; n=28; Tetrapoda|Re...    44   0.004
UniRef50_A1Z876 Cluster: CG12908-PB, isoform B; n=2; Drosophila ...    42   0.010
UniRef50_Q4RPY1 Cluster: Chromosome 17 SCAF15006, whole genome s...    40   0.039
UniRef50_Q04901 Cluster: Entactin/nidogen; n=1; Halocynthia rore...    40   0.051
UniRef50_Q7Q440 Cluster: ENSANGP00000021850; n=1; Anopheles gamb...    38   0.16 
UniRef50_Q172X3 Cluster: Nidogen; n=1; Aedes aegypti|Rep: Nidoge...    38   0.16 
UniRef50_Q93791 Cluster: Putative uncharacterized protein nid-1;...    37   0.36 
UniRef50_UPI0000584B22 Cluster: PREDICTED: similar to Low-densit...    36   0.84 
UniRef50_Q6XYD3 Cluster: LP2570; n=1; Homo sapiens|Rep: LP2570 -...    35   1.5  
UniRef50_UPI00006A008C Cluster: UPI00006A008C related cluster; n...    34   2.6  
UniRef50_A7S9Z7 Cluster: Predicted protein; n=1; Nematostella ve...    34   2.6  
UniRef50_Q8IKQ4 Cluster: Putative uncharacterized protein; n=4; ...    34   3.4  
UniRef50_UPI0000ECAC64 Cluster: Stabilin-1 precursor (Fasciclin,...    33   5.9  
UniRef50_A5V5G9 Cluster: TonB-dependent receptor precursor; n=1;...    33   5.9  
UniRef50_Q22AZ6 Cluster: Putative uncharacterized protein; n=1; ...    33   5.9  
UniRef50_A7S7T4 Cluster: Predicted protein; n=1; Nematostella ve...    33   5.9  
UniRef50_A6SE27 Cluster: Predicted protein; n=1; Botryotinia fuc...    33   5.9  

>UniRef50_UPI00003BFA45 Cluster: PREDICTED: similar to
            Nidogen/entactin CG12908-PA, isoform A; n=1; Apis
            mellifera|Rep: PREDICTED: similar to Nidogen/entactin
            CG12908-PA, isoform A - Apis mellifera
          Length = 1263

 Score = 62.9 bits (146), Expect = 6e-09
 Identities = 31/73 (42%), Positives = 39/73 (53%), Gaps = 2/73 (2%)
 Frame = +1

Query: 1    RTLKIEIIDTITQARGQ-IDIPRS-TIRLYGVANAPSECPGAANVCSQRNGNCNAGQLCL 174
            +T KIE+    T  R Q I +P   + +LYG+   P  CP   N C    G C+  QLCL
Sbjct: 1181 KTHKIEVAMKSTGDRKQAISVPPGGSGKLYGIVVVPESCPRVTNACQFEGGRCSKNQLCL 1240

Query: 175  PNGSGGRSCLNGD 213
            PNG  GRSC+  D
Sbjct: 1241 PNGQNGRSCVCAD 1253


>UniRef50_UPI0000D55DA8 Cluster: PREDICTED: similar to CG12908-PA,
            isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
            similar to CG12908-PA, isoform A - Tribolium castaneum
          Length = 1320

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 19/52 (36%), Positives = 28/52 (53%)
 Frame = +1

Query: 49   QIDIPRSTIRLYGVANAPSECPGAANVCSQRNGNCNAGQLCLPNGSGGRSCL 204
            Q+ +  S  +L+G+   P  CP   NVC      C    +CLPNG+G R+C+
Sbjct: 1254 QVPLGGSGNKLFGLVAVPQSCPQLTNVCQYYKDQCPVDHICLPNGAGSRTCV 1305


>UniRef50_UPI0000F1F8DC Cluster: PREDICTED: similar to Nidogen-1
            precursor (Entactin); n=1; Danio rerio|Rep: PREDICTED:
            similar to Nidogen-1 precursor (Entactin) - Danio rerio
          Length = 942

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
 Frame = +1

Query: 10   KIEIIDTITQARGQIDI--PRSTIRLYGVANAPSECPGAANVCSQRNGNCNAGQLCLPNG 183
            ++ ++      R ++D   P+   RLYG+  A + CP   N CS  NG C    LCL   
Sbjct: 865  RVSVVVVDRHLRREVDEFQPQKRTRLYGITTAHARCPAGQNYCSSNNGGCT--HLCLAT- 921

Query: 184  SGGRSC 201
              GRSC
Sbjct: 922  PAGRSC 927


>UniRef50_A6QNS6 Cluster: NID1 protein; n=5; Euteleostomi|Rep: NID1
            protein - Bos taurus (Bovine)
          Length = 1241

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 21/47 (44%), Positives = 25/47 (53%)
 Frame = +1

Query: 61   PRSTIRLYGVANAPSECPGAANVCSQRNGNCNAGQLCLPNGSGGRSC 201
            P    RLYG+ +A S+CP   N CS  NG C    LCL    G R+C
Sbjct: 1183 PHKQTRLYGITSALSQCPEGHNYCSVNNGGCT--HLCLAT-PGSRTC 1226


>UniRef50_P14543 Cluster: Nidogen-1 precursor; n=28; Tetrapoda|Rep:
            Nidogen-1 precursor - Homo sapiens (Human)
          Length = 1247

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 21/47 (44%), Positives = 24/47 (51%)
 Frame = +1

Query: 61   PRSTIRLYGVANAPSECPGAANVCSQRNGNCNAGQLCLPNGSGGRSC 201
            P    RLYG+  A S+CP   N CS  NG C    LCL    G R+C
Sbjct: 1189 PHKQTRLYGITTALSQCPQGHNYCSVNNGGCT--HLCLAT-PGSRTC 1232


>UniRef50_A1Z876 Cluster: CG12908-PB, isoform B; n=2; Drosophila
            melanogaster|Rep: CG12908-PB, isoform B - Drosophila
            melanogaster (Fruit fly)
          Length = 1370

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
 Frame = +1

Query: 4    TLKIEIIDTITQARGQIDIPR-STIRLYGVANAPSECPGAANVCSQRNGNCNAGQLCLPN 180
            T K+EI+D++   +  I  P   + ++YG+      CP   + C   NG C   +LCL N
Sbjct: 1286 TKKVEIVDSLGARQTPIQPPFFGSHKMYGMTVVEQHCPQYQSPCQISNGGCTDSRLCLVN 1345

Query: 181  --GSGGRSC 201
                 G+SC
Sbjct: 1346 RQAPSGKSC 1354


>UniRef50_Q4RPY1 Cluster: Chromosome 17 SCAF15006, whole genome
            shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
            Chromosome 17 SCAF15006, whole genome shotgun sequence -
            Tetraodon nigroviridis (Green puffer)
          Length = 1396

 Score = 40.3 bits (90), Expect = 0.039
 Identities = 19/47 (40%), Positives = 24/47 (51%)
 Frame = +1

Query: 61   PRSTIRLYGVANAPSECPGAANVCSQRNGNCNAGQLCLPNGSGGRSC 201
            P+   +LYG+    ++CP   N CS  NG C    LCL     GRSC
Sbjct: 1339 PQKRTKLYGLTTTYAQCPSGQNYCSVNNGGCT--HLCLATPL-GRSC 1382


>UniRef50_Q04901 Cluster: Entactin/nidogen; n=1; Halocynthia
            roretzi|Rep: Entactin/nidogen - Halocynthia roretzi (Sea
            squirt)
          Length = 1161

 Score = 39.9 bits (89), Expect = 0.051
 Identities = 22/48 (45%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
 Frame = +1

Query: 61   PRSTI-RLYGVANAPSECPGAANVCSQRNGNCNAGQLCLPNGSGGRSC 201
            PR T  + YG+A   S+CP   N C Q NG C+   LCLP    GR C
Sbjct: 1105 PRGTHGQTYGIAVVHSQCPRGYNYCGQDNGGCS--HLCLPT-PYGRVC 1149


>UniRef50_Q7Q440 Cluster: ENSANGP00000021850; n=1; Anopheles gambiae
            str. PEST|Rep: ENSANGP00000021850 - Anopheles gambiae
            str. PEST
          Length = 1289

 Score = 38.3 bits (85), Expect = 0.16
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
 Frame = +1

Query: 4    TLKIEIIDTITQARGQIDIPR-STIRLYGVANAPSECPGAANVCSQRNGNCNAGQLCL-- 174
            T KIE I+     +  I+ P     ++YG+     +CP   + C   NG+C   ++CL  
Sbjct: 1207 TKKIESINLYGVRQKPINSPVFGNHKMYGMTAVTDKCPLFHSPCVSNNGDCPEDKICLIN 1266

Query: 175  PNGSGGRSC 201
            P    GRSC
Sbjct: 1267 PRAPSGRSC 1275


>UniRef50_Q172X3 Cluster: Nidogen; n=1; Aedes aegypti|Rep: Nidogen -
            Aedes aegypti (Yellowfever mosquito)
          Length = 1298

 Score = 38.3 bits (85), Expect = 0.16
 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 3/75 (4%)
 Frame = +1

Query: 4    TLKIEIIDTITQARGQIDIPR-STIRLYGVANAPSECPGAANVCSQRNGNCNAGQLCL-- 174
            T K+E I+   +    I  P     ++YG+     +CP   + C   NG+C   ++CL  
Sbjct: 1215 TKKVESINAYGEREKGIPSPVFGNHKMYGMTAVTDKCPLFYSPCVVNNGDCTEKRICLSN 1274

Query: 175  PNGSGGRSCLNGDAN 219
            P    GR C   D N
Sbjct: 1275 PRAPSGRGCKCADDN 1289


>UniRef50_Q93791 Cluster: Putative uncharacterized protein nid-1; n=2;
            Caenorhabditis|Rep: Putative uncharacterized protein
            nid-1 - Caenorhabditis elegans
          Length = 1584

 Score = 37.1 bits (82), Expect = 0.36
 Identities = 16/42 (38%), Positives = 22/42 (52%)
 Frame = +1

Query: 76   RLYGVANAPSECPGAANVCSQRNGNCNAGQLCLPNGSGGRSC 201
            +++G+   P  C G +  CS+ NG C    LCLP G  G  C
Sbjct: 1535 KVFGILAVPKSCVGPSTPCSEDNGGCQ--HLCLP-GQNGAVC 1573


>UniRef50_UPI0000584B22 Cluster: PREDICTED: similar to Low-density
           lipoprotein receptor-related protein 4 precursor
           (Multiple epidermal growth factor-like domains 7); n=1;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           Low-density lipoprotein receptor-related protein 4
           precursor (Multiple epidermal growth factor-like domains
           7) - Strongylocentrotus purpuratus
          Length = 948

 Score = 35.9 bits (79), Expect = 0.84
 Identities = 23/56 (41%), Positives = 27/56 (48%)
 Frame = +1

Query: 46  GQIDIPRSTIRLYGVANAPSECPGAANVCSQRNGNCNAGQLCLPNGSGGRSCLNGD 213
           G+ D  R    L+ V NA    P   N CS+ NG C+   LCLP    GRSC   D
Sbjct: 294 GKRDFTRPNA-LFAVTNA--SLPSGINSCSENNGGCST--LCLPTAI-GRSCACAD 343


>UniRef50_Q6XYD3 Cluster: LP2570; n=1; Homo sapiens|Rep: LP2570 -
           Homo sapiens (Human)
          Length = 117

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 22/68 (32%), Positives = 30/68 (44%)
 Frame = -3

Query: 218 LASPFRQLLPPLPLGRHSCPALQLPFLCEQTLAAPGHSLGALATPYNRIVDLGMSICPLA 39
           L  P    L PLP  +HSC   Q     +     PG   G  A+P ++I   G  +  LA
Sbjct: 2   LPQPLEFTLTPLPSAQHSCLKFQPNHRKQLLCEGPGTGRGWQASPNSQIAVTGYDLTSLA 61

Query: 38  WVIVSMIS 15
              VS++S
Sbjct: 62  RSRVSLLS 69


>UniRef50_UPI00006A008C Cluster: UPI00006A008C related cluster; n=3;
            Xenopus tropicalis|Rep: UPI00006A008C UniRef100 entry -
            Xenopus tropicalis
          Length = 1403

 Score = 34.3 bits (75), Expect = 2.6
 Identities = 15/35 (42%), Positives = 19/35 (54%)
 Frame = +1

Query: 100  PSECPGAANVCSQRNGNCNAGQLCLPNGSGGRSCL 204
            PS  P  +N C   NG C+  QLCLP     R+C+
Sbjct: 928  PSRQPQGSNPCQINNGGCS--QLCLPTSETTRTCM 960


>UniRef50_A7S9Z7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 1137

 Score = 34.3 bits (75), Expect = 2.6
 Identities = 13/26 (50%), Positives = 16/26 (61%)
 Frame = +1

Query: 124 NVCSQRNGNCNAGQLCLPNGSGGRSC 201
           ++C   NG C+A  LCL  G G RSC
Sbjct: 647 DLCQVDNGGCHANALCLKTGPGKRSC 672


>UniRef50_Q8IKQ4 Cluster: Putative uncharacterized protein; n=4;
           Plasmodium|Rep: Putative uncharacterized protein -
           Plasmodium falciparum (isolate 3D7)
          Length = 553

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
 Frame = +2

Query: 359 NVIHVD*PLFKINYCFSISKLQIKFETLLIEYIYVRFFNRYSINIQV*L*KWTDLNNLK- 535
           N   V+  L  + + F  +K QI F+ +   Y  V   N  S    +   KW  LN LK 
Sbjct: 420 NASSVNKNLENLYFDFPYNKNQIIFKPVFYPYKNVEIINN-SFQNYIKNIKWDKLNKLKD 478

Query: 536 ITFFYHVTTKTFNLFKRVNI 595
             F+Y+   K FN  K + I
Sbjct: 479 AQFYYNTKNKIFNFSKEIYI 498


>UniRef50_UPI0000ECAC64 Cluster: Stabilin-1 precursor (Fasciclin,
            EGF-like, laminin-type EGF-like and link
            domain-containing scavenger receptor 1) (FEEL-1) (MS-1
            antigen).; n=2; Gallus gallus|Rep: Stabilin-1 precursor
            (Fasciclin, EGF-like, laminin-type EGF-like and link
            domain-containing scavenger receptor 1) (FEEL-1) (MS-1
            antigen). - Gallus gallus
          Length = 2291

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 16/39 (41%), Positives = 19/39 (48%)
 Frame = +1

Query: 85   GVANAPSECPGAANVCSQRNGNCNAGQLCLPNGSGGRSC 201
            G A     C  A N C   NG C+   +C+P G G RSC
Sbjct: 940  GYAGDGHNCD-AINPCLMDNGGCHDLAICVPLGGGERSC 977


>UniRef50_A5V5G9 Cluster: TonB-dependent receptor precursor; n=1;
           Sphingomonas wittichii RW1|Rep: TonB-dependent receptor
           precursor - Sphingomonas wittichii RW1
          Length = 809

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 15/54 (27%), Positives = 26/54 (48%)
 Frame = -1

Query: 253 ADNYSLSAKVNSWRHRSDNSFPHFHWVGTAVRRCSYRFSASKRWQPRDTRSARW 92
           +D  +L+  VN+W+ +SD   P F  + +          A++ + P D R A W
Sbjct: 246 SDRLTLNLNVNAWQDKSDPQAPQFFGLQSQAPATLPPLIAAQPFTPHDARLAEW 299


>UniRef50_Q22AZ6 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1326

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 18/51 (35%), Positives = 25/51 (49%)
 Frame = -1

Query: 598  SNINPFKKVKCFRSDVVKKRNFQII*VCPFLQLNLNINTIPIKKSNVNVFY 446
            + +  F + K  R+ + KK+N QII   P L        I +KKS  N FY
Sbjct: 1245 NQLKTFMRWKLLRNSIKKKKNEQIIINIPQLDRTRLTENISLKKSKSNFFY 1295


>UniRef50_A7S7T4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 330

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 12/25 (48%), Positives = 15/25 (60%)
 Frame = +3

Query: 18  NHRHNNPGERANRHSKIDDTVIRCC 92
           NHRHNN   R++RHS  D  +   C
Sbjct: 168 NHRHNNNNNRSSRHSTADSAIDSIC 192


>UniRef50_A6SE27 Cluster: Predicted protein; n=1; Botryotinia
           fuckeliana B05.10|Rep: Predicted protein - Botryotinia
           fuckeliana B05.10
          Length = 238

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 20/63 (31%), Positives = 29/63 (46%)
 Frame = +1

Query: 13  IEIIDTITQARGQIDIPRSTIRLYGVANAPSECPGAANVCSQRNGNCNAGQLCLPNGSGG 192
           I +I T         +P  T   +G +N  S C G A +C    GN ++G  C+  GS G
Sbjct: 91  IALITTSANMEDYPYVPSQTTAGHGYSN--SACGGGAGICIPSGGNDDSG-FCVAAGSCG 147

Query: 193 RSC 201
            +C
Sbjct: 148 ITC 150


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 613,049,715
Number of Sequences: 1657284
Number of extensions: 12384777
Number of successful extensions: 32563
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 30345
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 32481
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 48541014171
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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