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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= heS30263
         (687 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AY054122-1|AAL14867.1|  180|Homo sapiens Ells2 protein.                71   5e-12
AF513707-1|AAQ08115.1|  242|Homo sapiens ZNRF2 protein protein.        71   5e-12
BC007235-1|AAH07235.1|  227|Homo sapiens ZNRF1 protein protein.        60   7e-09
AL136903-1|CAB66837.1|  227|Homo sapiens hypothetical protein pr...    60   7e-09
AF378524-1|AAK69753.1|  227|Homo sapiens nin283 protein.               60   7e-09
AL834440-1|CAD39100.1|  271|Homo sapiens hypothetical protein pr...    53   8e-07
BC032365-1|AAH32365.1|  860|Homo sapiens SH2 domain containing 3...    32   2.2  
BC027962-1|AAH27962.1|  703|Homo sapiens SH2D3C protein protein.       32   2.2  
AY358440-1|AAQ89948.1|  703|Homo sapiens NSP3 protein.                 32   2.2  
AY358089-1|AAQ88456.1|  688|Homo sapiens NSP3 protein.                 32   2.2  
AL162586-7|CAI39766.1|  860|Homo sapiens SH2 domain containing 3...    32   2.2  
AL162586-4|CAI39763.1|  703|Homo sapiens SH2 domain containing 3...    32   2.2  
AL162586-3|CAI39762.1|  324|Homo sapiens SH2 domain containing 3...    32   2.2  
AL162586-2|CAI39761.1|  702|Homo sapiens SH2 domain containing 3...    32   2.2  
AL162426-7|CAI41182.1|  860|Homo sapiens SH2 domain containing 3...    32   2.2  
AL162426-4|CAI41179.1|  703|Homo sapiens SH2 domain containing 3...    32   2.2  
AL162426-3|CAI41178.1|  324|Homo sapiens SH2 domain containing 3...    32   2.2  
AL162426-2|CAI41177.1|  702|Homo sapiens SH2 domain containing 3...    32   2.2  
AF124251-1|AAD28246.1|  703|Homo sapiens SH2-containing protein ...    32   2.2  
AY672590-1|AAT75005.1|  347|Homo sapiens retinitis pigmentosa 1 ...    31   5.1  
AF152242-1|AAD46774.1| 2156|Homo sapiens retinitis pigmentosa 1 ...    31   5.1  
AF146592-1|AAD46769.1| 2156|Homo sapiens retinitis pigmentosa 1 ...    31   5.1  
AF143226-1|AAD44197.1| 2156|Homo sapiens retinitis pigmentosa RP...    31   5.1  
AF141021-1|AAD42072.1| 2156|Homo sapiens oxygen-regulated protei...    31   5.1  

>AY054122-1|AAL14867.1|  180|Homo sapiens Ells2 protein.
          Length = 180

 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 35/62 (56%), Positives = 43/62 (69%), Gaps = 2/62 (3%)
 Frame = +1

Query: 469 GGVAGSGPCLRSXPLPSHI--WSINGIKCPVXSKFVLPDDIECHLVMCLTRPRLSYNEDV 642
           GG  G GP L    LP+H+      G KCPV SKFV  D+++ HLVMCLT+PR++YNEDV
Sbjct: 71  GGSPG-GPRLVIGSLPAHLSPHMFGGFKCPVCSKFVSSDEMDLHLVMCLTKPRITYNEDV 129

Query: 643 LS 648
           LS
Sbjct: 130 LS 131


>AF513707-1|AAQ08115.1|  242|Homo sapiens ZNRF2 protein protein.
          Length = 242

 Score = 70.5 bits (165), Expect = 5e-12
 Identities = 35/62 (56%), Positives = 43/62 (69%), Gaps = 2/62 (3%)
 Frame = +1

Query: 469 GGVAGSGPCLRSXPLPSHI--WSINGIKCPVXSKFVLPDDIECHLVMCLTRPRLSYNEDV 642
           GG  G GP L    LP+H+      G KCPV SKFV  D+++ HLVMCLT+PR++YNEDV
Sbjct: 133 GGSPG-GPRLVIGSLPAHLSPHMFGGFKCPVCSKFVSSDEMDLHLVMCLTKPRITYNEDV 191

Query: 643 LS 648
           LS
Sbjct: 192 LS 193


>BC007235-1|AAH07235.1|  227|Homo sapiens ZNRF1 protein protein.
          Length = 227

 Score = 60.1 bits (139), Expect = 7e-09
 Identities = 28/51 (54%), Positives = 37/51 (72%), Gaps = 5/51 (9%)
 Frame = +1

Query: 511 LPSHI---W--SINGIKCPVXSKFVLPDDIECHLVMCLTRPRLSYNEDVLS 648
           LP HI   W  S +G KCP+ SK V  D++E H +MCL++PRLSYN+DVL+
Sbjct: 128 LPLHIAPRWFSSHSGFKCPICSKSVASDEMEMHFIMCLSKPRLSYNDDVLT 178


>AL136903-1|CAB66837.1|  227|Homo sapiens hypothetical protein
           protein.
          Length = 227

 Score = 60.1 bits (139), Expect = 7e-09
 Identities = 28/51 (54%), Positives = 37/51 (72%), Gaps = 5/51 (9%)
 Frame = +1

Query: 511 LPSHI---W--SINGIKCPVXSKFVLPDDIECHLVMCLTRPRLSYNEDVLS 648
           LP HI   W  S +G KCP+ SK V  D++E H +MCL++PRLSYN+DVL+
Sbjct: 128 LPLHIAPRWFSSHSGFKCPICSKSVASDEMEMHFIMCLSKPRLSYNDDVLT 178


>AF378524-1|AAK69753.1|  227|Homo sapiens nin283 protein.
          Length = 227

 Score = 60.1 bits (139), Expect = 7e-09
 Identities = 28/51 (54%), Positives = 37/51 (72%), Gaps = 5/51 (9%)
 Frame = +1

Query: 511 LPSHI---W--SINGIKCPVXSKFVLPDDIECHLVMCLTRPRLSYNEDVLS 648
           LP HI   W  S +G KCP+ SK V  D++E H +MCL++PRLSYN+DVL+
Sbjct: 128 LPLHIAPRWFSSHSGFKCPICSKSVASDEMEMHFIMCLSKPRLSYNDDVLT 178


>AL834440-1|CAD39100.1|  271|Homo sapiens hypothetical protein
           protein.
          Length = 271

 Score = 53.2 bits (122), Expect = 8e-07
 Identities = 25/46 (54%), Positives = 32/46 (69%), Gaps = 5/46 (10%)
 Frame = +1

Query: 511 LPSHI---W--SINGIKCPVXSKFVLPDDIECHLVMCLTRPRLSYN 633
           LP HI   W  S +G KCP+ SK V  D++E H +MCL++PRLSYN
Sbjct: 121 LPLHIAPRWFSSHSGFKCPICSKSVASDEMEMHFIMCLSKPRLSYN 166


>BC032365-1|AAH32365.1|  860|Homo sapiens SH2 domain containing 3C
           protein.
          Length = 860

 Score = 31.9 bits (69), Expect = 2.2
 Identities = 22/76 (28%), Positives = 39/76 (51%)
 Frame = +2

Query: 176 GCKGEHCERGAESSRKDILD*LRVGRVSGAEGFSLLRAIPGIQVSNXRQRARSLSSVPDL 355
           G KG H +R + +    + D L   +V+ ++G     ++P  + S  R  A S+  +PDL
Sbjct: 349 GPKGSHMKRRSVT----MTDGLTADKVTRSDGCPTSTSLPRPRDS-IRSCALSMDQIPDL 403

Query: 356 HASHEAIAIPPNSQSY 403
           H+    I+  P+S +Y
Sbjct: 404 HSPMSPISESPSSPAY 419


>BC027962-1|AAH27962.1|  703|Homo sapiens SH2D3C protein protein.
          Length = 703

 Score = 31.9 bits (69), Expect = 2.2
 Identities = 22/76 (28%), Positives = 39/76 (51%)
 Frame = +2

Query: 176 GCKGEHCERGAESSRKDILD*LRVGRVSGAEGFSLLRAIPGIQVSNXRQRARSLSSVPDL 355
           G KG H +R + +    + D L   +V+ ++G     ++P  + S  R  A S+  +PDL
Sbjct: 192 GPKGSHMKRRSVT----MTDGLTADKVTRSDGCPTSTSLPRPRDS-IRSCALSMDQIPDL 246

Query: 356 HASHEAIAIPPNSQSY 403
           H+    I+  P+S +Y
Sbjct: 247 HSPMSPISESPSSPAY 262


>AY358440-1|AAQ89948.1|  703|Homo sapiens NSP3 protein.
          Length = 703

 Score = 31.9 bits (69), Expect = 2.2
 Identities = 22/76 (28%), Positives = 39/76 (51%)
 Frame = +2

Query: 176 GCKGEHCERGAESSRKDILD*LRVGRVSGAEGFSLLRAIPGIQVSNXRQRARSLSSVPDL 355
           G KG H +R + +    + D L   +V+ ++G     ++P  + S  R  A S+  +PDL
Sbjct: 192 GPKGSHMKRRSVT----MTDGLTADKVTRSDGCPTSTSLPRPRDS-IRSCALSMDQIPDL 246

Query: 356 HASHEAIAIPPNSQSY 403
           H+    I+  P+S +Y
Sbjct: 247 HSPMSPISESPSSPAY 262


>AY358089-1|AAQ88456.1|  688|Homo sapiens NSP3 protein.
          Length = 688

 Score = 31.9 bits (69), Expect = 2.2
 Identities = 22/76 (28%), Positives = 39/76 (51%)
 Frame = +2

Query: 176 GCKGEHCERGAESSRKDILD*LRVGRVSGAEGFSLLRAIPGIQVSNXRQRARSLSSVPDL 355
           G KG H +R + +    + D L   +V+ ++G     ++P  + S  R  A S+  +PDL
Sbjct: 177 GPKGSHMKRRSVT----MTDGLTADKVTRSDGCPTSTSLPRPRDS-IRSCALSMDQIPDL 231

Query: 356 HASHEAIAIPPNSQSY 403
           H+    I+  P+S +Y
Sbjct: 232 HSPMSPISESPSSPAY 247


>AL162586-7|CAI39766.1|  860|Homo sapiens SH2 domain containing 3C
           protein.
          Length = 860

 Score = 31.9 bits (69), Expect = 2.2
 Identities = 22/76 (28%), Positives = 39/76 (51%)
 Frame = +2

Query: 176 GCKGEHCERGAESSRKDILD*LRVGRVSGAEGFSLLRAIPGIQVSNXRQRARSLSSVPDL 355
           G KG H +R + +    + D L   +V+ ++G     ++P  + S  R  A S+  +PDL
Sbjct: 349 GPKGSHMKRRSVT----MTDGLTADKVTRSDGCPTSTSLPRPRDS-IRSCALSMDQIPDL 403

Query: 356 HASHEAIAIPPNSQSY 403
           H+    I+  P+S +Y
Sbjct: 404 HSPMSPISESPSSPAY 419


>AL162586-4|CAI39763.1|  703|Homo sapiens SH2 domain containing 3C
           protein.
          Length = 703

 Score = 31.9 bits (69), Expect = 2.2
 Identities = 22/76 (28%), Positives = 39/76 (51%)
 Frame = +2

Query: 176 GCKGEHCERGAESSRKDILD*LRVGRVSGAEGFSLLRAIPGIQVSNXRQRARSLSSVPDL 355
           G KG H +R + +    + D L   +V+ ++G     ++P  + S  R  A S+  +PDL
Sbjct: 192 GPKGSHMKRRSVT----MTDGLTADKVTRSDGCPTSTSLPRPRDS-IRSCALSMDQIPDL 246

Query: 356 HASHEAIAIPPNSQSY 403
           H+    I+  P+S +Y
Sbjct: 247 HSPMSPISESPSSPAY 262


>AL162586-3|CAI39762.1|  324|Homo sapiens SH2 domain containing 3C
           protein.
          Length = 324

 Score = 31.9 bits (69), Expect = 2.2
 Identities = 22/76 (28%), Positives = 39/76 (51%)
 Frame = +2

Query: 176 GCKGEHCERGAESSRKDILD*LRVGRVSGAEGFSLLRAIPGIQVSNXRQRARSLSSVPDL 355
           G KG H +R + +    + D L   +V+ ++G     ++P  + S  R  A S+  +PDL
Sbjct: 185 GPKGSHMKRRSVT----MTDGLTADKVTRSDGCPTSTSLPRPRDS-IRSCALSMDQIPDL 239

Query: 356 HASHEAIAIPPNSQSY 403
           H+    I+  P+S +Y
Sbjct: 240 HSPMSPISESPSSPAY 255


>AL162586-2|CAI39761.1|  702|Homo sapiens SH2 domain containing 3C
           protein.
          Length = 702

 Score = 31.9 bits (69), Expect = 2.2
 Identities = 22/76 (28%), Positives = 39/76 (51%)
 Frame = +2

Query: 176 GCKGEHCERGAESSRKDILD*LRVGRVSGAEGFSLLRAIPGIQVSNXRQRARSLSSVPDL 355
           G KG H +R + +    + D L   +V+ ++G     ++P  + S  R  A S+  +PDL
Sbjct: 191 GPKGSHMKRRSVT----MTDGLTADKVTRSDGCPTSTSLPRPRDS-IRSCALSMDQIPDL 245

Query: 356 HASHEAIAIPPNSQSY 403
           H+    I+  P+S +Y
Sbjct: 246 HSPMSPISESPSSPAY 261


>AL162426-7|CAI41182.1|  860|Homo sapiens SH2 domain containing 3C
           protein.
          Length = 860

 Score = 31.9 bits (69), Expect = 2.2
 Identities = 22/76 (28%), Positives = 39/76 (51%)
 Frame = +2

Query: 176 GCKGEHCERGAESSRKDILD*LRVGRVSGAEGFSLLRAIPGIQVSNXRQRARSLSSVPDL 355
           G KG H +R + +    + D L   +V+ ++G     ++P  + S  R  A S+  +PDL
Sbjct: 349 GPKGSHMKRRSVT----MTDGLTADKVTRSDGCPTSTSLPRPRDS-IRSCALSMDQIPDL 403

Query: 356 HASHEAIAIPPNSQSY 403
           H+    I+  P+S +Y
Sbjct: 404 HSPMSPISESPSSPAY 419


>AL162426-4|CAI41179.1|  703|Homo sapiens SH2 domain containing 3C
           protein.
          Length = 703

 Score = 31.9 bits (69), Expect = 2.2
 Identities = 22/76 (28%), Positives = 39/76 (51%)
 Frame = +2

Query: 176 GCKGEHCERGAESSRKDILD*LRVGRVSGAEGFSLLRAIPGIQVSNXRQRARSLSSVPDL 355
           G KG H +R + +    + D L   +V+ ++G     ++P  + S  R  A S+  +PDL
Sbjct: 192 GPKGSHMKRRSVT----MTDGLTADKVTRSDGCPTSTSLPRPRDS-IRSCALSMDQIPDL 246

Query: 356 HASHEAIAIPPNSQSY 403
           H+    I+  P+S +Y
Sbjct: 247 HSPMSPISESPSSPAY 262


>AL162426-3|CAI41178.1|  324|Homo sapiens SH2 domain containing 3C
           protein.
          Length = 324

 Score = 31.9 bits (69), Expect = 2.2
 Identities = 22/76 (28%), Positives = 39/76 (51%)
 Frame = +2

Query: 176 GCKGEHCERGAESSRKDILD*LRVGRVSGAEGFSLLRAIPGIQVSNXRQRARSLSSVPDL 355
           G KG H +R + +    + D L   +V+ ++G     ++P  + S  R  A S+  +PDL
Sbjct: 185 GPKGSHMKRRSVT----MTDGLTADKVTRSDGCPTSTSLPRPRDS-IRSCALSMDQIPDL 239

Query: 356 HASHEAIAIPPNSQSY 403
           H+    I+  P+S +Y
Sbjct: 240 HSPMSPISESPSSPAY 255


>AL162426-2|CAI41177.1|  702|Homo sapiens SH2 domain containing 3C
           protein.
          Length = 702

 Score = 31.9 bits (69), Expect = 2.2
 Identities = 22/76 (28%), Positives = 39/76 (51%)
 Frame = +2

Query: 176 GCKGEHCERGAESSRKDILD*LRVGRVSGAEGFSLLRAIPGIQVSNXRQRARSLSSVPDL 355
           G KG H +R + +    + D L   +V+ ++G     ++P  + S  R  A S+  +PDL
Sbjct: 191 GPKGSHMKRRSVT----MTDGLTADKVTRSDGCPTSTSLPRPRDS-IRSCALSMDQIPDL 245

Query: 356 HASHEAIAIPPNSQSY 403
           H+    I+  P+S +Y
Sbjct: 246 HSPMSPISESPSSPAY 261


>AF124251-1|AAD28246.1|  703|Homo sapiens SH2-containing protein
           Nsp3 protein.
          Length = 703

 Score = 31.9 bits (69), Expect = 2.2
 Identities = 22/76 (28%), Positives = 39/76 (51%)
 Frame = +2

Query: 176 GCKGEHCERGAESSRKDILD*LRVGRVSGAEGFSLLRAIPGIQVSNXRQRARSLSSVPDL 355
           G KG H +R + +    + D L   +V+ ++G     ++P  + S  R  A S+  +PDL
Sbjct: 192 GPKGSHMKRRSVT----MTDGLTADKVTRSDGCPTSTSLPRPRDS-IRSCALSMDQIPDL 246

Query: 356 HASHEAIAIPPNSQSY 403
           H+    I+  P+S +Y
Sbjct: 247 HSPMSPISESPSSPAY 262


>AY672590-1|AAT75005.1|  347|Homo sapiens retinitis pigmentosa 1
           protein.
          Length = 347

 Score = 30.7 bits (66), Expect = 5.1
 Identities = 13/34 (38%), Positives = 20/34 (58%)
 Frame = -2

Query: 212 TLPPVRSARLCTHNDSVTQIANMSCTETEDHENS 111
           TL P++SA +C +  SV   +N S +  + H NS
Sbjct: 251 TLKPIKSAPVCRNETSVVNCSNNSFSGNDPHTNS 284


>AF152242-1|AAD46774.1| 2156|Homo sapiens retinitis pigmentosa 1
            protein protein.
          Length = 2156

 Score = 30.7 bits (66), Expect = 5.1
 Identities = 13/34 (38%), Positives = 20/34 (58%)
 Frame = -2

Query: 212  TLPPVRSARLCTHNDSVTQIANMSCTETEDHENS 111
            TL P++SA +C +  SV   +N S +  + H NS
Sbjct: 928  TLKPIKSAPVCRNETSVVNCSNNSFSGNDPHTNS 961


>AF146592-1|AAD46769.1| 2156|Homo sapiens retinitis pigmentosa 1
            protein protein.
          Length = 2156

 Score = 30.7 bits (66), Expect = 5.1
 Identities = 13/34 (38%), Positives = 20/34 (58%)
 Frame = -2

Query: 212  TLPPVRSARLCTHNDSVTQIANMSCTETEDHENS 111
            TL P++SA +C +  SV   +N S +  + H NS
Sbjct: 928  TLKPIKSAPVCRNETSVVNCSNNSFSGNDPHTNS 961


>AF143226-1|AAD44197.1| 2156|Homo sapiens retinitis pigmentosa RP1
            protein protein.
          Length = 2156

 Score = 30.7 bits (66), Expect = 5.1
 Identities = 13/34 (38%), Positives = 20/34 (58%)
 Frame = -2

Query: 212  TLPPVRSARLCTHNDSVTQIANMSCTETEDHENS 111
            TL P++SA +C +  SV   +N S +  + H NS
Sbjct: 928  TLKPIKSAPVCRNETSVVNCSNNSFSGNDPHTNS 961


>AF141021-1|AAD42072.1| 2156|Homo sapiens oxygen-regulated protein 1
            protein.
          Length = 2156

 Score = 30.7 bits (66), Expect = 5.1
 Identities = 13/34 (38%), Positives = 20/34 (58%)
 Frame = -2

Query: 212  TLPPVRSARLCTHNDSVTQIANMSCTETEDHENS 111
            TL P++SA +C +  SV   +N S +  + H NS
Sbjct: 928  TLKPIKSAPVCRNETSVVNCSNNSFSGNDPHTNS 961


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 91,996,431
Number of Sequences: 237096
Number of extensions: 1857254
Number of successful extensions: 5517
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 5315
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5515
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7839245960
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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