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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= heS30235
         (742 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q177T5 Cluster: Huntingtin interacting protein; n=2; Cu...    38   0.26 
UniRef50_A6NWM1 Cluster: Putative uncharacterized protein; n=1; ...    36   1.4  
UniRef50_Q2NFR0 Cluster: Putative uncharacterized protein; n=2; ...    35   2.4  
UniRef50_UPI000150A218 Cluster: hypothetical protein TTHERM_0018...    34   3.2  
UniRef50_A6NME8 Cluster: Uncharacterized protein ENSP00000372122...    34   3.2  
UniRef50_Q5CY81 Cluster: Eukaryotic DNA topoisomerase I; n=2; Cr...    34   4.2  
UniRef50_A5ZTM2 Cluster: Putative uncharacterized protein; n=3; ...    33   5.6  
UniRef50_Q9I7U4-3 Cluster: Isoform B of Q9I7U4 ; n=6; Sophophora...    33   9.7  
UniRef50_Q23QS1 Cluster: Putative uncharacterized protein; n=1; ...    33   9.7  
UniRef50_A5DWL0 Cluster: Putative uncharacterized protein; n=1; ...    33   9.7  
UniRef50_Q9I7U4 Cluster: Titin; n=7; Endopterygota|Rep: Titin - ...    33   9.7  

>UniRef50_Q177T5 Cluster: Huntingtin interacting protein; n=2;
            Culicidae|Rep: Huntingtin interacting protein - Aedes
            aegypti (Yellowfever mosquito)
          Length = 2367

 Score = 37.9 bits (84), Expect = 0.26
 Identities = 24/69 (34%), Positives = 40/69 (57%), Gaps = 1/69 (1%)
 Frame = +2

Query: 467  KGSSQAFF*PSKQNKSD-HSVDIPKCKTEYNDKQRHYSVDSPSLDTKKKERLNSCSSLPS 643
            K SS+    PS+  KSD HS    K ++E   K++H S +  + ++K+K R   CS +PS
Sbjct: 823  KRSSKEMEKPSR--KSDKHS----KRRSESETKKKHSSSEQKAKESKEKSRSTDCSPVPS 876

Query: 644  NIGNKRRMS 670
             +G+ ++ S
Sbjct: 877  KVGSSKKSS 885


>UniRef50_A6NWM1 Cluster: Putative uncharacterized protein; n=1;
           Bacteroides capillosus ATCC 29799|Rep: Putative
           uncharacterized protein - Bacteroides capillosus ATCC
           29799
          Length = 575

 Score = 35.5 bits (78), Expect = 1.4
 Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 4/45 (8%)
 Frame = -3

Query: 623 NSDVPFFSCQDLVSPLNNVSVYHYIQSCILE----YQHYDLICFA 501
           N D+ FFSCQ+  S L   S  HYI+   LE    Y+ + L CFA
Sbjct: 352 NHDIKFFSCQNHNSGLRKCSSTHYIRLDFLEQVVLYEIHRLACFA 396


>UniRef50_Q2NFR0 Cluster: Putative uncharacterized protein; n=2;
           Methanosphaera stadtmanae DSM 3091|Rep: Putative
           uncharacterized protein - Methanosphaera stadtmanae
           (strain DSM 3091)
          Length = 75

 Score = 34.7 bits (76), Expect = 2.4
 Identities = 17/40 (42%), Positives = 24/40 (60%), Gaps = 1/40 (2%)
 Frame = -3

Query: 545 SCILEYQ-HYDLICFALMVRRMPVMILFFSFHFDRNIMFI 429
           SC   +Q HYDLI F + V  +P +I  F FH+D  + F+
Sbjct: 36  SCSTTFQFHYDLILFTVFVV-VPFVIFIFQFHYDLILFFM 74


>UniRef50_UPI000150A218 Cluster: hypothetical protein TTHERM_00189310;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00189310 - Tetrahymena thermophila SB210
          Length = 1538

 Score = 34.3 bits (75), Expect = 3.2
 Identities = 21/69 (30%), Positives = 38/69 (55%), Gaps = 1/69 (1%)
 Frame = +1

Query: 274  ILQLLERRMSHLNTRMQKSTI*RKSPNQSQKITIITLPNMTKTKIHHSNHV-KINMMFLS 450
            I +L ++R+ HL  R+QK  +     N+ Q+  ++  PN T+   H+SN V   ++M L 
Sbjct: 1007 IPKLAKKRLEHLQDRLQKE-LQFSEENEKQQQLLLFNPNATQYLSHNSNSVSSSSLMKLK 1065

Query: 451  K*KLKKRII 477
              K K++ +
Sbjct: 1066 SLKFKRQTL 1074


>UniRef50_A6NME8 Cluster: Uncharacterized protein ENSP00000372122;
           n=10; Amniota|Rep: Uncharacterized protein
           ENSP00000372122 - Homo sapiens (Human)
          Length = 686

 Score = 34.3 bits (75), Expect = 3.2
 Identities = 21/76 (27%), Positives = 38/76 (50%)
 Frame = +2

Query: 8   KKTPQQKNT*SRLKKNLSMITRSERNPKKKEERIQRTNVYLKSNGMIDTDMINLKKMIRN 187
           K  P  KN   ++ KN S++     +PK+K+  + ++ ++     MI  D +NL   I+N
Sbjct: 435 KFVPVFKNRLLQMNKNTSVLG----SPKRKQHDVTQSKLFSLKTSMIQHDKLNLGPAIKN 490

Query: 188 VISRRILKAKAGSLHE 235
             S  I    A +L++
Sbjct: 491 RYSSNIQMQAANNLNQ 506


>UniRef50_Q5CY81 Cluster: Eukaryotic DNA topoisomerase I; n=2;
           Cryptosporidium|Rep: Eukaryotic DNA topoisomerase I -
           Cryptosporidium parvum Iowa II
          Length = 653

 Score = 33.9 bits (74), Expect = 4.2
 Identities = 22/53 (41%), Positives = 32/53 (60%), Gaps = 3/53 (5%)
 Frame = +2

Query: 500 KQNKSDHSVDIPKCKTE--YNDKQRHYSVD-SPSLDTKKKERLNSCSSLPSNI 649
           K NKS    D+PK  TE  +N KQR Y ++ + SLD  +K +++S  S  SN+
Sbjct: 539 KNNKSVTISDLPKLSTEVSFNGKQRKYPINLNSSLDVVQK-KIDSIKSKISNL 590


>UniRef50_A5ZTM2 Cluster: Putative uncharacterized protein; n=3;
           Clostridiales|Rep: Putative uncharacterized protein -
           Ruminococcus obeum ATCC 29174
          Length = 313

 Score = 33.5 bits (73), Expect = 5.6
 Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
 Frame = +2

Query: 8   KKTPQQKNT*SRLKKNLSMITRSERNPKKK--EERIQRTNVYLKSNGMIDTDMINLKKMI 181
           KK+ QQ+ +       +SMI  +   P+KK  E+ +Q  +  +K  G++   +++ KK  
Sbjct: 43  KKSSQQETSNGERMMKISMIEPNREQPRKKFDEDALQELSESIKQYGILQPLLVSDKKDY 102

Query: 182 RNVIS--RRILKAKAGSLHEMKQLEK 253
             +++  RR   AK   L E+  + K
Sbjct: 103 YEIVAGERRWRAAKMAGLKEVPVVVK 128


>UniRef50_Q9I7U4-3 Cluster: Isoform B of Q9I7U4 ; n=6; Sophophora|Rep:
             Isoform B of Q9I7U4 - Drosophila melanogaster (Fruit fly)
          Length = 17903

 Score = 32.7 bits (71), Expect = 9.7
 Identities = 14/34 (41%), Positives = 20/34 (58%)
 Frame = +3

Query: 414   LKPCENKHDVPVKVKTEEKDHHRHSSDHQSKTNQ 515
             L+P + KH  P K + EE D   + SDH  K+N+
Sbjct: 11634 LRPKKFKHSKPEKAELEEADLGAYESDHSDKSNK 11667


>UniRef50_Q23QS1 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 7232

 Score = 32.7 bits (71), Expect = 9.7
 Identities = 12/23 (52%), Positives = 16/23 (69%)
 Frame = -3

Query: 605  FSCQDLVSPLNNVSVYHYIQSCI 537
            + C+DL SPLNN+  YH  +S I
Sbjct: 5510 YRCEDLTSPLNNLDYYHVTKSII 5532


>UniRef50_A5DWL0 Cluster: Putative uncharacterized protein; n=1;
            Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
            uncharacterized protein - Lodderomyces elongisporus
            (Yeast) (Saccharomyces elongisporus)
          Length = 1634

 Score = 32.7 bits (71), Expect = 9.7
 Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 6/58 (10%)
 Frame = +2

Query: 515  DHSVDIPKCKTEYNDKQRHYSVDSPS--LDTKKKERLNSCSS--LPSNIG--NKRRMS 670
            D   D  +  T+YNDKQ H  +DS S  +  KK E+ +   +  +  N+G  N RRMS
Sbjct: 1537 DFRKDSREISTQYNDKQDHMDIDSVSANIPVKKSEKGSPQMNAYINCNVGSENSRRMS 1594


>UniRef50_Q9I7U4 Cluster: Titin; n=7; Endopterygota|Rep: Titin -
             Drosophila melanogaster (Fruit fly)
          Length = 18074

 Score = 32.7 bits (71), Expect = 9.7
 Identities = 14/34 (41%), Positives = 20/34 (58%)
 Frame = +3

Query: 414   LKPCENKHDVPVKVKTEEKDHHRHSSDHQSKTNQ 515
             L+P + KH  P K + EE D   + SDH  K+N+
Sbjct: 11945 LRPKKFKHSKPEKAELEEADLGAYESDHSDKSNK 11978


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 536,810,132
Number of Sequences: 1657284
Number of extensions: 9028070
Number of successful extensions: 31911
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 28983
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 31392
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 60500186565
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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