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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= heS30160
         (719 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X56976-1|CAA40296.1| 1058|Homo sapiens ubiquitin activating enzy...    97   7e-20
X52897-1|CAA37078.1|  803|Homo sapiens protein ( Human A1S9 mRNA...    97   7e-20
M58028-1|AAA61246.1| 1058|Homo sapiens ubiquitin-activating enzy...    97   7e-20
BC013041-1|AAH13041.1| 1058|Homo sapiens ubiquitin-activating en...    97   7e-20
AL513366-14|CAI41710.1|  506|Homo sapiens ubiquitin-activating e...    97   7e-20
AL513366-12|CAI41708.1| 1058|Homo sapiens ubiquitin-activating e...    97   7e-20
AJ003111-1|CAA05866.1|   38|Homo sapiens ubiquitin activating en...    52   2e-06
EF623993-1|ABR25253.1| 1052|Homo sapiens ubiquitin-activating en...    42   0.002
BC126486-1|AAI26487.1| 1052|Homo sapiens ubiquitin-activating en...    42   0.002
BC126484-1|AAI26485.1| 1052|Homo sapiens ubiquitin-activating en...    42   0.002
AY359880-1|AAQ63403.1|  578|Homo sapiens hypothetical protein FL...    42   0.002
AL832458-1|CAD89959.1| 1052|Homo sapiens hypothetical protein pr...    42   0.002
AL832015-1|CAD89908.1| 1052|Homo sapiens hypothetical protein pr...    42   0.002
AK001670-1|BAA91824.1|  459|Homo sapiens protein ( Homo sapiens ...    42   0.002
AC096720-2|AAY40999.1|  787|Homo sapiens unknown protein.              42   0.002
AB014773-1|BAB19785.1| 1052|Homo sapiens MOP-4 protein.                42   0.002
AY634366-1|AAT47557.1|  225|Homo sapiens PMP22 claudin domain-co...    31   3.1  

>X56976-1|CAA40296.1| 1058|Homo sapiens ubiquitin activating enzyme E1
            protein.
          Length = 1058

 Score = 96.7 bits (230), Expect = 7e-20
 Identities = 48/76 (63%), Positives = 57/76 (75%), Gaps = 6/76 (7%)
 Frame = -2

Query: 685  LWDRFEVKG------EITLQQFLDHFKNEHKLEITMLSQGVCMLYSFFMPKAKRLERLNL 524
            LWDRFEV+G      E+TL+QFLD+FK EHKLEITMLSQGV MLYSFFMP AK  ERL+ 
Sbjct: 954  LWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQ 1013

Query: 523  PMSEVSQKCPRRSWNR 476
            PM+E+  +  +R   R
Sbjct: 1014 PMTEIVSRVSKRKLGR 1029



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 27/39 (69%), Positives = 33/39 (84%)
 Frame = -1

Query: 509  VTKVSKKKLEPHVNALVFELCCNDDDGNDVEVPYVKYTL 393
            V++VSK+KL  HV ALV ELCCND+ G DVEVPYV+YT+
Sbjct: 1019 VSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTI 1057


>X52897-1|CAA37078.1|  803|Homo sapiens protein ( Human A1S9 mRNA
           for A1S9 protein of unknown function. ).
          Length = 803

 Score = 96.7 bits (230), Expect = 7e-20
 Identities = 48/76 (63%), Positives = 57/76 (75%), Gaps = 6/76 (7%)
 Frame = -2

Query: 685 LWDRFEVKG------EITLQQFLDHFKNEHKLEITMLSQGVCMLYSFFMPKAKRLERLNL 524
           LWDRFEV+G      E+TL+QFLD+FK EHKLEITMLSQGV MLYSFFMP AK  ERL+ 
Sbjct: 699 LWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQ 758

Query: 523 PMSEVSQKCPRRSWNR 476
           PM+E+  +  +R   R
Sbjct: 759 PMTEIVSRVSKRKLGR 774



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 27/39 (69%), Positives = 33/39 (84%)
 Frame = -1

Query: 509 VTKVSKKKLEPHVNALVFELCCNDDDGNDVEVPYVKYTL 393
           V++VSK+KL  HV ALV ELCCND+ G DVEVPYV+YT+
Sbjct: 764 VSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTI 802


>M58028-1|AAA61246.1| 1058|Homo sapiens ubiquitin-activating enzyme E1
            protein.
          Length = 1058

 Score = 96.7 bits (230), Expect = 7e-20
 Identities = 48/76 (63%), Positives = 57/76 (75%), Gaps = 6/76 (7%)
 Frame = -2

Query: 685  LWDRFEVKG------EITLQQFLDHFKNEHKLEITMLSQGVCMLYSFFMPKAKRLERLNL 524
            LWDRFEV+G      E+TL+QFLD+FK EHKLEITMLSQGV MLYSFFMP AK  ERL+ 
Sbjct: 954  LWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQ 1013

Query: 523  PMSEVSQKCPRRSWNR 476
            PM+E+  +  +R   R
Sbjct: 1014 PMTEIVSRVSKRKLGR 1029



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 27/39 (69%), Positives = 33/39 (84%)
 Frame = -1

Query: 509  VTKVSKKKLEPHVNALVFELCCNDDDGNDVEVPYVKYTL 393
            V++VSK+KL  HV ALV ELCCND+ G DVEVPYV+YT+
Sbjct: 1019 VSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTI 1057


>BC013041-1|AAH13041.1| 1058|Homo sapiens ubiquitin-activating enzyme
            E1 (A1S9T and BN75 temperature sensitivity compleme
            protein.
          Length = 1058

 Score = 96.7 bits (230), Expect = 7e-20
 Identities = 48/76 (63%), Positives = 57/76 (75%), Gaps = 6/76 (7%)
 Frame = -2

Query: 685  LWDRFEVKG------EITLQQFLDHFKNEHKLEITMLSQGVCMLYSFFMPKAKRLERLNL 524
            LWDRFEV+G      E+TL+QFLD+FK EHKLEITMLSQGV MLYSFFMP AK  ERL+ 
Sbjct: 954  LWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQ 1013

Query: 523  PMSEVSQKCPRRSWNR 476
            PM+E+  +  +R   R
Sbjct: 1014 PMTEIVSRVSKRKLGR 1029



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 27/39 (69%), Positives = 33/39 (84%)
 Frame = -1

Query: 509  VTKVSKKKLEPHVNALVFELCCNDDDGNDVEVPYVKYTL 393
            V++VSK+KL  HV ALV ELCCND+ G DVEVPYV+YT+
Sbjct: 1019 VSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTI 1057


>AL513366-14|CAI41710.1|  506|Homo sapiens ubiquitin-activating
           enzyme E1 (A1S9T and BN75 temperature sensitivity
           compleme protein.
          Length = 506

 Score = 96.7 bits (230), Expect = 7e-20
 Identities = 48/76 (63%), Positives = 57/76 (75%), Gaps = 6/76 (7%)
 Frame = -2

Query: 685 LWDRFEVKG------EITLQQFLDHFKNEHKLEITMLSQGVCMLYSFFMPKAKRLERLNL 524
           LWDRFEV+G      E+TL+QFLD+FK EHKLEITMLSQGV MLYSFFMP AK  ERL+ 
Sbjct: 402 LWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQ 461

Query: 523 PMSEVSQKCPRRSWNR 476
           PM+E+  +  +R   R
Sbjct: 462 PMTEIVSRVSKRKLGR 477



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 27/39 (69%), Positives = 33/39 (84%)
 Frame = -1

Query: 509 VTKVSKKKLEPHVNALVFELCCNDDDGNDVEVPYVKYTL 393
           V++VSK+KL  HV ALV ELCCND+ G DVEVPYV+YT+
Sbjct: 467 VSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTI 505


>AL513366-12|CAI41708.1| 1058|Homo sapiens ubiquitin-activating enzyme
            E1 (A1S9T and BN75 temperature sensitivity compleme
            protein.
          Length = 1058

 Score = 96.7 bits (230), Expect = 7e-20
 Identities = 48/76 (63%), Positives = 57/76 (75%), Gaps = 6/76 (7%)
 Frame = -2

Query: 685  LWDRFEVKG------EITLQQFLDHFKNEHKLEITMLSQGVCMLYSFFMPKAKRLERLNL 524
            LWDRFEV+G      E+TL+QFLD+FK EHKLEITMLSQGV MLYSFFMP AK  ERL+ 
Sbjct: 954  LWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQ 1013

Query: 523  PMSEVSQKCPRRSWNR 476
            PM+E+  +  +R   R
Sbjct: 1014 PMTEIVSRVSKRKLGR 1029



 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 27/39 (69%), Positives = 33/39 (84%)
 Frame = -1

Query: 509  VTKVSKKKLEPHVNALVFELCCNDDDGNDVEVPYVKYTL 393
            V++VSK+KL  HV ALV ELCCND+ G DVEVPYV+YT+
Sbjct: 1019 VSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTI 1057


>AJ003111-1|CAA05866.1|   38|Homo sapiens ubiquitin activating
           enzyme E1 protein.
          Length = 38

 Score = 52.4 bits (120), Expect = 2e-06
 Identities = 27/38 (71%), Positives = 31/38 (81%), Gaps = 6/38 (15%)
 Frame = -2

Query: 676 RFEVKG------EITLQQFLDHFKNEHKLEITMLSQGV 581
           RFEV+G      E+TL+QFLD+FK EHKLEITMLSQGV
Sbjct: 1   RFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGV 38


>EF623993-1|ABR25253.1| 1052|Homo sapiens ubiquitin-activating enzyme
            6 protein.
          Length = 1052

 Score = 41.9 bits (94), Expect = 0.002
 Identities = 24/53 (45%), Positives = 34/53 (64%), Gaps = 3/53 (5%)
 Frame = -2

Query: 685  LWDRFEVKG--EITLQQFLDHFKNEHKLEITMLSQGVCMLYSFFMP-KAKRLE 536
            +WDR+ V G  + TL  F++  K ++ +E TM+ QGV MLY   MP  AKRL+
Sbjct: 954  IWDRWTVHGKEDFTLLDFINAVKEKYGIEPTMVVQGVKMLYVPVMPGHAKRLK 1006


>BC126486-1|AAI26487.1| 1052|Homo sapiens ubiquitin-activating enzyme
            E1-like 2 protein.
          Length = 1052

 Score = 41.9 bits (94), Expect = 0.002
 Identities = 24/53 (45%), Positives = 34/53 (64%), Gaps = 3/53 (5%)
 Frame = -2

Query: 685  LWDRFEVKG--EITLQQFLDHFKNEHKLEITMLSQGVCMLYSFFMP-KAKRLE 536
            +WDR+ V G  + TL  F++  K ++ +E TM+ QGV MLY   MP  AKRL+
Sbjct: 954  IWDRWTVHGKEDFTLLDFINAVKEKYGIEPTMVVQGVKMLYVPVMPGHAKRLK 1006


>BC126484-1|AAI26485.1| 1052|Homo sapiens ubiquitin-activating enzyme
            E1-like 2 protein.
          Length = 1052

 Score = 41.9 bits (94), Expect = 0.002
 Identities = 24/53 (45%), Positives = 34/53 (64%), Gaps = 3/53 (5%)
 Frame = -2

Query: 685  LWDRFEVKG--EITLQQFLDHFKNEHKLEITMLSQGVCMLYSFFMP-KAKRLE 536
            +WDR+ V G  + TL  F++  K ++ +E TM+ QGV MLY   MP  AKRL+
Sbjct: 954  IWDRWTVHGKEDFTLLDFINAVKEKYGIEPTMVVQGVKMLYVPVMPGHAKRLK 1006


>AY359880-1|AAQ63403.1|  578|Homo sapiens hypothetical protein
           FLJ10808 isoform protein.
          Length = 578

 Score = 41.9 bits (94), Expect = 0.002
 Identities = 24/53 (45%), Positives = 34/53 (64%), Gaps = 3/53 (5%)
 Frame = -2

Query: 685 LWDRFEVKG--EITLQQFLDHFKNEHKLEITMLSQGVCMLYSFFMP-KAKRLE 536
           +WDR+ V G  + TL  F++  K ++ +E TM+ QGV MLY   MP  AKRL+
Sbjct: 480 IWDRWTVHGKEDFTLLDFINAVKEKYGIEPTMVVQGVKMLYVPVMPGHAKRLK 532


>AL832458-1|CAD89959.1| 1052|Homo sapiens hypothetical protein
            protein.
          Length = 1052

 Score = 41.9 bits (94), Expect = 0.002
 Identities = 24/53 (45%), Positives = 34/53 (64%), Gaps = 3/53 (5%)
 Frame = -2

Query: 685  LWDRFEVKG--EITLQQFLDHFKNEHKLEITMLSQGVCMLYSFFMP-KAKRLE 536
            +WDR+ V G  + TL  F++  K ++ +E TM+ QGV MLY   MP  AKRL+
Sbjct: 954  IWDRWTVHGKEDFTLLDFINAVKEKYGIEPTMVVQGVKMLYVPVMPGHAKRLK 1006


>AL832015-1|CAD89908.1| 1052|Homo sapiens hypothetical protein
            protein.
          Length = 1052

 Score = 41.9 bits (94), Expect = 0.002
 Identities = 24/53 (45%), Positives = 34/53 (64%), Gaps = 3/53 (5%)
 Frame = -2

Query: 685  LWDRFEVKG--EITLQQFLDHFKNEHKLEITMLSQGVCMLYSFFMP-KAKRLE 536
            +WDR+ V G  + TL  F++  K ++ +E TM+ QGV MLY   MP  AKRL+
Sbjct: 954  IWDRWTVHGKEDFTLLDFINAVKEKYGIEPTMVVQGVKMLYVPVMPGHAKRLK 1006


>AK001670-1|BAA91824.1|  459|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10808 fis, clone NT2RP4000879, weakly similar to
           UBIQUITIN-ACTIVATING ENZYME E1. ).
          Length = 459

 Score = 41.9 bits (94), Expect = 0.002
 Identities = 24/53 (45%), Positives = 34/53 (64%), Gaps = 3/53 (5%)
 Frame = -2

Query: 685 LWDRFEVKG--EITLQQFLDHFKNEHKLEITMLSQGVCMLYSFFMP-KAKRLE 536
           +WDR+ V G  + TL  F++  K ++ +E TM+ QGV MLY   MP  AKRL+
Sbjct: 361 IWDRWTVHGKEDFTLLDFINAVKEKYGIEPTMVVQGVKMLYVPVMPGHAKRLK 413


>AC096720-2|AAY40999.1|  787|Homo sapiens unknown protein.
          Length = 787

 Score = 41.9 bits (94), Expect = 0.002
 Identities = 24/53 (45%), Positives = 34/53 (64%), Gaps = 3/53 (5%)
 Frame = -2

Query: 685 LWDRFEVKG--EITLQQFLDHFKNEHKLEITMLSQGVCMLYSFFMP-KAKRLE 536
           +WDR+ V G  + TL  F++  K ++ +E TM+ QGV MLY   MP  AKRL+
Sbjct: 689 IWDRWTVHGKEDFTLLDFINAVKEKYGIEPTMVVQGVKMLYVPVMPGHAKRLK 741


>AB014773-1|BAB19785.1| 1052|Homo sapiens MOP-4 protein.
          Length = 1052

 Score = 41.9 bits (94), Expect = 0.002
 Identities = 24/53 (45%), Positives = 34/53 (64%), Gaps = 3/53 (5%)
 Frame = -2

Query: 685  LWDRFEVKG--EITLQQFLDHFKNEHKLEITMLSQGVCMLYSFFMP-KAKRLE 536
            +WDR+ V G  + TL  F++  K ++ +E TM+ QGV MLY   MP  AKRL+
Sbjct: 954  IWDRWTVHGKEDFTLLDFINAVKEKYGIEPTMVVQGVKMLYVPVMPGHAKRLK 1006


>AY634366-1|AAT47557.1|  225|Homo sapiens PMP22 claudin
           domain-containing protein protein.
          Length = 225

 Score = 31.5 bits (68), Expect = 3.1
 Identities = 19/66 (28%), Positives = 29/66 (43%)
 Frame = -3

Query: 687 IYGTDLKLKERLHYSNF*ITSKTNTSWRSPCCLKVCACFIRSSCPKPSGWND*TCQCRRC 508
           +Y   LK  + +H+SN+ IT    T++ +   L VC       C   +     +C C   
Sbjct: 119 LYHNKLKQGQSMHFSNYRITWIMYTAYLNVFFLSVCGVLSLLECKLSTS----SCTCLNI 174

Query: 507 HKSVQE 490
           HKS  E
Sbjct: 175 HKSDNE 180


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 89,749,127
Number of Sequences: 237096
Number of extensions: 1794137
Number of successful extensions: 3153
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 2953
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3144
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8455186714
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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