Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= heS30128
(628 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X82245-1|CAA57709.1| 1246|Homo sapiens nidogen protein. 93 7e-19
M30269-1|AAA59932.1| 1247|Homo sapiens nidogen protein. 93 7e-19
M27445-1|AAA57261.1| 581|Homo sapiens nidogen protein. 93 7e-19
BC045606-1|AAH45606.1| 1114|Homo sapiens NID1 protein protein. 93 7e-19
AL139161-2|CAI23422.1| 1247|Homo sapiens nidogen 1 protein. 93 7e-19
AL139161-1|CAI23421.1| 1114|Homo sapiens nidogen 1 protein. 93 7e-19
AL122018-2|CAI22681.1| 1247|Homo sapiens nidogen 1 protein. 93 7e-19
AL122018-1|CAI22680.1| 1114|Homo sapiens nidogen 1 protein. 93 7e-19
AB209448-1|BAD92685.1| 1241|Homo sapiens nidogen (enactin) varia... 93 7e-19
AB084910-1|BAD83615.1| 1905|Homo sapiens low density lipoprotein... 88 2e-17
AB011540-1|BAA32468.1| 1576|Homo sapiens MEGF7 protein. 88 2e-17
AF283321-1|AAK52433.1| 1611|Homo sapiens low density lipoprotein... 87 4e-17
AF077820-1|AAC72791.1| 1615|Homo sapiens LDL receptor member LR3... 87 4e-17
AF064548-1|AAC36467.1| 1615|Homo sapiens low-density lipoprotein... 87 4e-17
AB017498-1|BAA33051.1| 1615|Homo sapiens Lipoprotein Receptor Re... 87 4e-17
D86425-1|BAA13087.1| 1376|Homo sapiens osteonidogen protein. 84 3e-16
BC035608-1|AAH35608.1| 969|Homo sapiens NID2 protein protein. 84 3e-16
AJ223500-1|CAA11418.1| 1375|Homo sapiens nidogen-2 protein. 84 3e-16
AB009799-1|BAA24112.1| 1376|Homo sapiens osteonidogen protein. 84 3e-16
BC126405-1|AAI26406.1| 1613|Homo sapiens low density lipoprotein... 83 1e-15
BC117136-1|AAI17137.1| 1613|Homo sapiens low density lipoprotein... 83 1e-15
AF074264-1|AAC33006.1| 1613|Homo sapiens LDL receptor-related pr... 83 1e-15
AB231861-1|BAE19679.1| 1950|Homo sapiens low-density lipoprotein... 82 2e-15
X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related prec... 81 4e-15
DQ314873-1|ABC40732.1| 4544|Homo sapiens low density lipoprotein... 81 4e-15
AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-re... 81 4e-15
U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein. 79 2e-14
S73145-1|AAB30825.1| 268|Homo sapiens calcium sensor protein pr... 79 2e-14
AC007556-2|AAX88965.1| 3881|Homo sapiens unknown protein. 79 2e-14
AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor g... 78 3e-14
AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor g... 78 3e-14
AF283374-1|AAL38108.1| 1731|Homo sapiens candidate tumor suppres... 77 5e-14
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein... 77 5e-14
AC117947-1|AAX88968.1| 346|Homo sapiens unknown protein. 77 5e-14
AB209683-1|BAD92920.1| 1477|Homo sapiens low density lipoprotein... 76 9e-14
AB209498-1|BAD92735.1| 2359|Homo sapiens low density lipoprotein... 76 9e-14
Z75190-1|CAA99509.1| 699|Homo sapiens apolipoprotein E receptor... 75 2e-13
D86407-2|BAA21825.1| 793|Homo sapiens ApoER2delta4-7 protein. 75 2e-13
D86407-1|BAA21824.1| 963|Homo sapiens ApoER2 protein. 75 2e-13
D50678-1|BAA09328.1| 963|Homo sapiens apolipoprotein E receptor... 75 2e-13
BC051836-1|AAH51836.2| 904|Homo sapiens low density lipoprotein... 75 2e-13
AL606760-4|CAI18908.1| 963|Homo sapiens low density lipoprotein... 75 2e-13
AL606760-3|CAI18909.1| 700|Homo sapiens low density lipoprotein... 75 2e-13
AL606760-2|CAI18910.1| 904|Homo sapiens low density lipoprotein... 75 2e-13
AL355483-3|CAI22781.1| 963|Homo sapiens low density lipoprotein... 75 2e-13
AL355483-2|CAI22782.1| 700|Homo sapiens low density lipoprotein... 75 2e-13
AL355483-1|CAI22780.1| 904|Homo sapiens low density lipoprotein... 75 2e-13
U04441-1|AAB02882.1| 1751|Homo sapiens glycoprotein 330 protein. 75 2e-13
AK054663-1|BAB70786.1| 820|Homo sapiens umor (LRPDIT) mRNA. pr... 73 8e-13
AC010740-1|AAY14689.1| 862|Homo sapiens unknown protein. 73 8e-13
X04571-1|CAA28240.1| 1207|Homo sapiens protein ( Human mRNA for ... 72 2e-12
BC113461-1|AAI13462.1| 1207|Homo sapiens epidermal growth factor... 72 2e-12
BC093731-1|AAH93731.1| 1207|Homo sapiens epidermal growth factor... 72 2e-12
AY506357-1|AAR84237.1| 1152|Homo sapiens truncated epidermal gro... 72 2e-12
S73849-1|AAB31735.1| 873|Homo sapiens very low density lipoprot... 68 2e-11
L22431-1|AAA61344.1| 873|Homo sapiens very low density lipoprot... 68 2e-11
L20470-1|AAA53684.1| 873|Homo sapiens very low density lipoprot... 68 2e-11
D16532-1|BAA03969.1| 873|Homo sapiens very low density lipoprot... 68 2e-11
D16494-1|BAA03946.1| 845|Homo sapiens very low density lipoprot... 68 2e-11
D16493-1|BAA03945.1| 873|Homo sapiens very low density lipoprot... 68 2e-11
DQ067198-1|AAY46157.1| 873|Homo sapiens very low density lipopr... 68 2e-11
BC142653-1|AAI42654.1| 845|Homo sapiens very low density lipopr... 68 2e-11
AL450467-4|CAH72453.1| 752|Homo sapiens very low density lipopr... 68 2e-11
AL450467-3|CAH72455.1| 845|Homo sapiens very low density lipopr... 68 2e-11
AL450467-2|CAH72454.1| 873|Homo sapiens very low density lipopr... 68 2e-11
AK092381-1|BAC03874.1| 752|Homo sapiens protein ( Homo sapiens ... 68 2e-11
BC139736-1|AAI39737.1| 224|Homo sapiens LRP5L protein protein. 67 5e-11
Y08110-1|CAA69325.1| 2214|Homo sapiens mosaic protein LR11 protein. 61 3e-09
U60975-1|AAC50891.2| 2214|Homo sapiens gp250 precursor protein. 61 3e-09
AF283342-1|AAL38107.1| 881|Homo sapiens candidate tumor suppres... 61 3e-09
AC073319-1|AAX93075.1| 585|Homo sapiens unknown protein. 61 3e-09
AC008178-1|AAY24266.1| 773|Homo sapiens unknown protein. 60 5e-09
L00352-1|AAA56833.1| 860|Homo sapiens low density lipoprotein r... 59 1e-08
BT007361-1|AAP36025.1| 860|Homo sapiens low density lipoprotein... 59 1e-08
BC014514-1|AAH14514.1| 860|Homo sapiens low density lipoprotein... 59 1e-08
AY324609-1|AAP72971.1| 860|Homo sapiens low density lipoprotein... 59 1e-08
AY114155-1|AAM56036.1| 860|Homo sapiens low density lipoprotein... 59 1e-08
AF217403-1|AAF24515.1| 837|Homo sapiens low density lipoprotein... 59 1e-08
AB209409-1|BAD92646.1| 870|Homo sapiens low density lipoprotein... 59 1e-08
AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppres... 57 6e-08
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein... 57 6e-08
BC021204-1|AAH21204.1| 439|Homo sapiens LRP1 protein protein. 52 1e-06
AC093039-1|AAX88911.1| 425|Homo sapiens unknown protein. 41 0.004
AC068195-1|AAX93243.1| 1126|Homo sapiens unknown protein. 40 0.010
AC108036-1|AAX93208.1| 449|Homo sapiens unknown protein. 37 0.067
AC068287-1|AAY24318.1| 223|Homo sapiens unknown protein. 31 3.3
AK123991-1|BAC85745.1| 155|Homo sapiens protein ( Homo sapiens ... 31 4.4
>X82245-1|CAA57709.1| 1246|Homo sapiens nidogen protein.
Length = 1246
Score = 93.1 bits (221), Expect = 7e-19
Identities = 46/85 (54%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D RNIFWTDS IEVA LD R+VLF ++ NPRGI RG ++WTDWNR N
Sbjct: 1028 DHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFET-DLVNPRGIVTDSVRGNLYWTDWNRDN 1086
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
PKIE + MDGT R +L+ D+ LP
Sbjct: 1087 PKIETSYMDGTNRRILV-QDDLGLP 1110
Score = 45.2 bits (102), Expect = 2e-04
Identities = 27/70 (38%), Positives = 39/70 (55%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
++WTD + +I A+L + Q++ +P GIAV IFWTD N +IE A
Sbjct: 991 VYWTDITEPSIGRASLHGGEPTTIIR-QDLGSPEGIAVDHLGRNIFWTDSNLD--RIEVA 1047
Query: 199 NMDGTERSVL 228
+DGT+R VL
Sbjct: 1048 KLDGTQRRVL 1057
Score = 42.7 bits (96), Expect = 0.001
Identities = 22/95 (23%), Positives = 38/95 (40%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
N + D ++C+ DAG +C++ E +YPF + G LY++DW+
Sbjct: 1111 NGLHFDAFSSQLCWVDAGTNRAECLNPSQPSRRKALEGLQYPFAVTSYGKNLYFTDWKMN 1170
Query: 435 KIEIIDTITQARGQIDIPRSTIRL*VLPTRRASVP 539
+ +D P RL + T + P
Sbjct: 1171 SVVALDLAISKETDAFQPHKQTRLYGITTALSQCP 1205
Score = 32.7 bits (71), Expect = 1.1
Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 1/40 (2%)
Frame = +2
Query: 509 GVANAPSECPGAANVCSQRNGNCNAGQLCLPN-GSXGXSC 625
G+ A S+CP N CS NG C LCL GS C
Sbjct: 1196 GITTALSQCPQGHNYCSVNNGGCT--HLCLATPGSRTCRC 1233
>M30269-1|AAA59932.1| 1247|Homo sapiens nidogen protein.
Length = 1247
Score = 93.1 bits (221), Expect = 7e-19
Identities = 46/85 (54%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D RNIFWTDS IEVA LD R+VLF ++ NPRGI RG ++WTDWNR N
Sbjct: 1029 DHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFET-DLVNPRGIVTDSVRGNLYWTDWNRDN 1087
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
PKIE + MDGT R +L+ D+ LP
Sbjct: 1088 PKIETSYMDGTNRRILV-QDDLGLP 1111
Score = 45.2 bits (102), Expect = 2e-04
Identities = 27/70 (38%), Positives = 39/70 (55%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
++WTD + +I A+L + Q++ +P GIAV IFWTD N +IE A
Sbjct: 992 VYWTDITEPSIGRASLHGGEPTTIIR-QDLGSPEGIAVDHLGRNIFWTDSNLD--RIEVA 1048
Query: 199 NMDGTERSVL 228
+DGT+R VL
Sbjct: 1049 KLDGTQRRVL 1058
Score = 42.7 bits (96), Expect = 0.001
Identities = 22/95 (23%), Positives = 38/95 (40%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
N + D ++C+ DAG +C++ E +YPF + G LY++DW+
Sbjct: 1112 NGLHFDAFSSQLCWVDAGTNRAECLNPSQPSRRKALEGLQYPFAVTSYGKNLYFTDWKMN 1171
Query: 435 KIEIIDTITQARGQIDIPRSTIRL*VLPTRRASVP 539
+ +D P RL + T + P
Sbjct: 1172 SVVALDLAISKETDAFQPHKQTRLYGITTALSQCP 1206
Score = 32.7 bits (71), Expect = 1.1
Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 1/40 (2%)
Frame = +2
Query: 509 GVANAPSECPGAANVCSQRNGNCNAGQLCLPN-GSXGXSC 625
G+ A S+CP N CS NG C LCL GS C
Sbjct: 1197 GITTALSQCPQGHNYCSVNNGGCT--HLCLATPGSRTCRC 1234
>M27445-1|AAA57261.1| 581|Homo sapiens nidogen protein.
Length = 581
Score = 93.1 bits (221), Expect = 7e-19
Identities = 46/85 (54%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D RNIFWTDS IEVA LD R+VLF ++ NPRGI RG ++WTDWNR N
Sbjct: 363 DHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFET-DLVNPRGIVTDSVRGNLYWTDWNRDN 421
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
PKIE + MDGT R +L+ D+ LP
Sbjct: 422 PKIETSYMDGTNRRILV-QDDLGLP 445
Score = 45.2 bits (102), Expect = 2e-04
Identities = 27/70 (38%), Positives = 39/70 (55%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
++WTD + +I A+L + Q++ +P GIAV IFWTD N +IE A
Sbjct: 326 VYWTDITEPSIGRASLHGGEPTTIIR-QDLGSPEGIAVDHLGRNIFWTDSNLD--RIEVA 382
Query: 199 NMDGTERSVL 228
+DGT+R VL
Sbjct: 383 KLDGTQRRVL 392
Score = 43.6 bits (98), Expect = 6e-04
Identities = 22/95 (23%), Positives = 38/95 (40%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
N + D ++C+ DAG +C++ E +YPF + G LY++DW+
Sbjct: 446 NGLTFDAFSSQLCWVDAGTNRAECLNPSQPSRRKALEGLQYPFAVTSYGKNLYFTDWKMN 505
Query: 435 KIEIIDTITQARGQIDIPRSTIRL*VLPTRRASVP 539
+ +D P RL + T + P
Sbjct: 506 SVVALDLAISKETDAFQPHKQTRLYGITTALSQCP 540
Score = 32.7 bits (71), Expect = 1.1
Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 1/40 (2%)
Frame = +2
Query: 509 GVANAPSECPGAANVCSQRNGNCNAGQLCLPN-GSXGXSC 625
G+ A S+CP N CS NG C LCL GS C
Sbjct: 531 GITTALSQCPQGHNYCSVNNGGCT--HLCLATPGSRTCRC 568
>BC045606-1|AAH45606.1| 1114|Homo sapiens NID1 protein protein.
Length = 1114
Score = 93.1 bits (221), Expect = 7e-19
Identities = 46/85 (54%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D RNIFWTDS IEVA LD R+VLF ++ NPRGI RG ++WTDWNR N
Sbjct: 896 DHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFET-DLVNPRGIVTDSVRGNLYWTDWNRDN 954
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
PKIE + MDGT R +L+ D+ LP
Sbjct: 955 PKIETSYMDGTNRRILV-QDDLGLP 978
Score = 45.2 bits (102), Expect = 2e-04
Identities = 27/70 (38%), Positives = 39/70 (55%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
++WTD + +I A+L + Q++ +P GIAV IFWTD N +IE A
Sbjct: 859 VYWTDITEPSIGRASLHGGEPTTIIR-QDLGSPEGIAVDHLGRNIFWTDSNLD--RIEVA 915
Query: 199 NMDGTERSVL 228
+DGT+R VL
Sbjct: 916 KLDGTQRRVL 925
Score = 43.6 bits (98), Expect = 6e-04
Identities = 22/95 (23%), Positives = 38/95 (40%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
N + D ++C+ DAG +C++ E +YPF + G LY++DW+
Sbjct: 979 NGLTFDAFSSQLCWVDAGTNRAECLNPSQPSRRKALEGLQYPFAVTSYGKNLYFTDWKMN 1038
Query: 435 KIEIIDTITQARGQIDIPRSTIRL*VLPTRRASVP 539
+ +D P RL + T + P
Sbjct: 1039 SVVALDLAISKETDAFQPHKQTRLYGITTALSQCP 1073
Score = 32.7 bits (71), Expect = 1.1
Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 1/40 (2%)
Frame = +2
Query: 509 GVANAPSECPGAANVCSQRNGNCNAGQLCLPN-GSXGXSC 625
G+ A S+CP N CS NG C LCL GS C
Sbjct: 1064 GITTALSQCPQGHNYCSVNNGGCT--HLCLATPGSRTCRC 1101
>AL139161-2|CAI23422.1| 1247|Homo sapiens nidogen 1 protein.
Length = 1247
Score = 93.1 bits (221), Expect = 7e-19
Identities = 46/85 (54%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D RNIFWTDS IEVA LD R+VLF ++ NPRGI RG ++WTDWNR N
Sbjct: 1029 DHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFET-DLVNPRGIVTDSVRGNLYWTDWNRDN 1087
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
PKIE + MDGT R +L+ D+ LP
Sbjct: 1088 PKIETSYMDGTNRRILV-QDDLGLP 1111
Score = 45.2 bits (102), Expect = 2e-04
Identities = 27/70 (38%), Positives = 39/70 (55%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
++WTD + +I A+L + Q++ +P GIAV IFWTD N +IE A
Sbjct: 992 VYWTDITEPSIGRASLHGGEPTTIIR-QDLGSPEGIAVDHLGRNIFWTDSNLD--RIEVA 1048
Query: 199 NMDGTERSVL 228
+DGT+R VL
Sbjct: 1049 KLDGTQRRVL 1058
Score = 43.6 bits (98), Expect = 6e-04
Identities = 22/95 (23%), Positives = 38/95 (40%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
N + D ++C+ DAG +C++ E +YPF + G LY++DW+
Sbjct: 1112 NGLTFDAFSSQLCWVDAGTNRAECLNPSQPSRRKALEGLQYPFAVTSYGKNLYFTDWKMN 1171
Query: 435 KIEIIDTITQARGQIDIPRSTIRL*VLPTRRASVP 539
+ +D P RL + T + P
Sbjct: 1172 SVVALDLAISKETDAFQPHKQTRLYGITTALSQCP 1206
Score = 32.7 bits (71), Expect = 1.1
Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 1/40 (2%)
Frame = +2
Query: 509 GVANAPSECPGAANVCSQRNGNCNAGQLCLPN-GSXGXSC 625
G+ A S+CP N CS NG C LCL GS C
Sbjct: 1197 GITTALSQCPQGHNYCSVNNGGCT--HLCLATPGSRTCRC 1234
>AL139161-1|CAI23421.1| 1114|Homo sapiens nidogen 1 protein.
Length = 1114
Score = 93.1 bits (221), Expect = 7e-19
Identities = 46/85 (54%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D RNIFWTDS IEVA LD R+VLF ++ NPRGI RG ++WTDWNR N
Sbjct: 896 DHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFET-DLVNPRGIVTDSVRGNLYWTDWNRDN 954
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
PKIE + MDGT R +L+ D+ LP
Sbjct: 955 PKIETSYMDGTNRRILV-QDDLGLP 978
Score = 45.2 bits (102), Expect = 2e-04
Identities = 27/70 (38%), Positives = 39/70 (55%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
++WTD + +I A+L + Q++ +P GIAV IFWTD N +IE A
Sbjct: 859 VYWTDITEPSIGRASLHGGEPTTIIR-QDLGSPEGIAVDHLGRNIFWTDSNLD--RIEVA 915
Query: 199 NMDGTERSVL 228
+DGT+R VL
Sbjct: 916 KLDGTQRRVL 925
Score = 43.6 bits (98), Expect = 6e-04
Identities = 22/95 (23%), Positives = 38/95 (40%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
N + D ++C+ DAG +C++ E +YPF + G LY++DW+
Sbjct: 979 NGLTFDAFSSQLCWVDAGTNRAECLNPSQPSRRKALEGLQYPFAVTSYGKNLYFTDWKMN 1038
Query: 435 KIEIIDTITQARGQIDIPRSTIRL*VLPTRRASVP 539
+ +D P RL + T + P
Sbjct: 1039 SVVALDLAISKETDAFQPHKQTRLYGITTALSQCP 1073
Score = 32.7 bits (71), Expect = 1.1
Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 1/40 (2%)
Frame = +2
Query: 509 GVANAPSECPGAANVCSQRNGNCNAGQLCLPN-GSXGXSC 625
G+ A S+CP N CS NG C LCL GS C
Sbjct: 1064 GITTALSQCPQGHNYCSVNNGGCT--HLCLATPGSRTCRC 1101
>AL122018-2|CAI22681.1| 1247|Homo sapiens nidogen 1 protein.
Length = 1247
Score = 93.1 bits (221), Expect = 7e-19
Identities = 46/85 (54%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D RNIFWTDS IEVA LD R+VLF ++ NPRGI RG ++WTDWNR N
Sbjct: 1029 DHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFET-DLVNPRGIVTDSVRGNLYWTDWNRDN 1087
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
PKIE + MDGT R +L+ D+ LP
Sbjct: 1088 PKIETSYMDGTNRRILV-QDDLGLP 1111
Score = 45.2 bits (102), Expect = 2e-04
Identities = 27/70 (38%), Positives = 39/70 (55%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
++WTD + +I A+L + Q++ +P GIAV IFWTD N +IE A
Sbjct: 992 VYWTDITEPSIGRASLHGGEPTTIIR-QDLGSPEGIAVDHLGRNIFWTDSNLD--RIEVA 1048
Query: 199 NMDGTERSVL 228
+DGT+R VL
Sbjct: 1049 KLDGTQRRVL 1058
Score = 43.6 bits (98), Expect = 6e-04
Identities = 22/95 (23%), Positives = 38/95 (40%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
N + D ++C+ DAG +C++ E +YPF + G LY++DW+
Sbjct: 1112 NGLTFDAFSSQLCWVDAGTNRAECLNPSQPSRRKALEGLQYPFAVTSYGKNLYFTDWKMN 1171
Query: 435 KIEIIDTITQARGQIDIPRSTIRL*VLPTRRASVP 539
+ +D P RL + T + P
Sbjct: 1172 SVVALDLAISKETDAFQPHKQTRLYGITTALSQCP 1206
Score = 32.7 bits (71), Expect = 1.1
Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 1/40 (2%)
Frame = +2
Query: 509 GVANAPSECPGAANVCSQRNGNCNAGQLCLPN-GSXGXSC 625
G+ A S+CP N CS NG C LCL GS C
Sbjct: 1197 GITTALSQCPQGHNYCSVNNGGCT--HLCLATPGSRTCRC 1234
>AL122018-1|CAI22680.1| 1114|Homo sapiens nidogen 1 protein.
Length = 1114
Score = 93.1 bits (221), Expect = 7e-19
Identities = 46/85 (54%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D RNIFWTDS IEVA LD R+VLF ++ NPRGI RG ++WTDWNR N
Sbjct: 896 DHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFET-DLVNPRGIVTDSVRGNLYWTDWNRDN 954
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
PKIE + MDGT R +L+ D+ LP
Sbjct: 955 PKIETSYMDGTNRRILV-QDDLGLP 978
Score = 45.2 bits (102), Expect = 2e-04
Identities = 27/70 (38%), Positives = 39/70 (55%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
++WTD + +I A+L + Q++ +P GIAV IFWTD N +IE A
Sbjct: 859 VYWTDITEPSIGRASLHGGEPTTIIR-QDLGSPEGIAVDHLGRNIFWTDSNLD--RIEVA 915
Query: 199 NMDGTERSVL 228
+DGT+R VL
Sbjct: 916 KLDGTQRRVL 925
Score = 43.6 bits (98), Expect = 6e-04
Identities = 22/95 (23%), Positives = 38/95 (40%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
N + D ++C+ DAG +C++ E +YPF + G LY++DW+
Sbjct: 979 NGLTFDAFSSQLCWVDAGTNRAECLNPSQPSRRKALEGLQYPFAVTSYGKNLYFTDWKMN 1038
Query: 435 KIEIIDTITQARGQIDIPRSTIRL*VLPTRRASVP 539
+ +D P RL + T + P
Sbjct: 1039 SVVALDLAISKETDAFQPHKQTRLYGITTALSQCP 1073
Score = 32.7 bits (71), Expect = 1.1
Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 1/40 (2%)
Frame = +2
Query: 509 GVANAPSECPGAANVCSQRNGNCNAGQLCLPN-GSXGXSC 625
G+ A S+CP N CS NG C LCL GS C
Sbjct: 1064 GITTALSQCPQGHNYCSVNNGGCT--HLCLATPGSRTCRC 1101
>AB209448-1|BAD92685.1| 1241|Homo sapiens nidogen (enactin) variant
protein.
Length = 1241
Score = 93.1 bits (221), Expect = 7e-19
Identities = 46/85 (54%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D RNIFWTDS IEVA LD R+VLF ++ NPRGI RG ++WTDWNR N
Sbjct: 1023 DHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFET-DLVNPRGIVTDSVRGNLYWTDWNRDN 1081
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
PKIE + MDGT R +L+ D+ LP
Sbjct: 1082 PKIETSYMDGTNRRILV-QDDLGLP 1105
Score = 43.6 bits (98), Expect = 6e-04
Identities = 22/95 (23%), Positives = 38/95 (40%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
N + D ++C+ DAG +C++ E +YPF + G LY++DW+
Sbjct: 1106 NGLTFDAFSSQLCWVDAGTNRAECLNPSQPSRRKALEGLQYPFAVTSYGKNLYFTDWKMN 1165
Query: 435 KIEIIDTITQARGQIDIPRSTIRL*VLPTRRASVP 539
+ +D P RL + T + P
Sbjct: 1166 SVVALDLAISKETDAFQPHKQTRLYGITTALSQCP 1200
Score = 35.5 bits (78), Expect = 0.16
Identities = 26/70 (37%), Positives = 34/70 (48%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
++WTD + +I A+L I GIAV IFWTD N +IE A
Sbjct: 991 VYWTDITEPSIGRASLHGG------EPTTIIRQEGIAVDHLGRNIFWTDSNLD--RIEVA 1042
Query: 199 NMDGTERSVL 228
+DGT+R VL
Sbjct: 1043 KLDGTQRRVL 1052
Score = 32.7 bits (71), Expect = 1.1
Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 1/40 (2%)
Frame = +2
Query: 509 GVANAPSECPGAANVCSQRNGNCNAGQLCLPN-GSXGXSC 625
G+ A S+CP N CS NG C LCL GS C
Sbjct: 1191 GITTALSQCPQGHNYCSVNNGGCT--HLCLATPGSRTCRC 1228
>AB084910-1|BAD83615.1| 1905|Homo sapiens low density lipoprotein
receptor-related protein 10 protein.
Length = 1905
Score = 88.2 bits (209), Expect = 2e-17
Identities = 40/79 (50%), Positives = 55/79 (69%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ARN++WTD+ + TIE + LD RKVL + ++ PR IAV P++G +FWTDW
Sbjct: 1436 DWVARNLYWTDTGRNTIEASRLDGSCRKVLIN-NSLDEPRAIAVFPRKGYLFWTDWGHI- 1493
Query: 181 PKIEWANMDGTERSVLLGS 237
KIE AN+DG+ER VL+ +
Sbjct: 1494 AKIERANLDGSERKVLINT 1512
Score = 81.8 bits (193), Expect = 2e-15
Identities = 38/76 (50%), Positives = 50/76 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++WTDS IEVANLD RKVL QN+ PR IA+HP G I+WTDW +
Sbjct: 519 DWVHDKLYWTDSGTSRIEVANLDGAHRKVLLW-QNLEKPRAIALHPMEGTIYWTDWG-NT 576
Query: 181 PKIEWANMDGTERSVL 228
P+IE ++MDG+ R ++
Sbjct: 577 PRIEASSMDGSGRRII 592
Score = 74.9 bits (176), Expect = 2e-13
Identities = 36/79 (45%), Positives = 47/79 (59%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++WTD+ IEVAN D +R VL +N+ PR I V P G ++WTDW S
Sbjct: 824 DWVTNKLYWTDAGTDRIEVANTDGSMRTVLIW-ENLDRPRDIVVEPMGGYMYWTDWGAS- 881
Query: 181 PKIEWANMDGTERSVLLGS 237
PKIE A MD + R V++ S
Sbjct: 882 PKIERAGMDASGRQVIISS 900
Score = 73.3 bits (172), Expect = 6e-13
Identities = 34/79 (43%), Positives = 52/79 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D R ++WTD+ IEV NLD +RKVL QN+ +PR I ++ + G ++WTDW N
Sbjct: 1132 DAIGRKVYWTDTGTNRIEVGNLDGSMRKVLV-WQNLDSPRAIVLYHEMGFMYWTDWG-EN 1189
Query: 181 PKIEWANMDGTERSVLLGS 237
K+E + MDG++R+VL+ +
Sbjct: 1190 AKLERSGMDGSDRAVLINN 1208
Score = 59.3 bits (137), Expect = 1e-08
Identities = 26/70 (37%), Positives = 44/70 (62%), Gaps = 1/70 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAINGDKLYWSDWRT 431
N +AID+ R+ +ADAG++ I+ L S++ I +PFGL + G+++YW+DW+T
Sbjct: 906 NGLAIDYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIYWTDWQT 965
Query: 432 LKIEIIDTIT 461
I+ D +T
Sbjct: 966 KSIQSADRLT 975
Score = 49.6 bits (113), Expect = 9e-06
Identities = 27/79 (34%), Positives = 45/79 (56%), Gaps = 2/79 (2%)
Frame = +1
Query: 1 DWSARN--IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
DW +R+ ++WTD TI A D ++V+ ++ +P G+A+ K++WTD
Sbjct: 779 DWDSRDDHVYWTDVSTDTISRAKWDGTGQEVVVDT-SLESPAGLAIDWVTNKLYWTD--A 835
Query: 175 SNPKIEWANMDGTERSVLL 231
+IE AN DG+ R+VL+
Sbjct: 836 GTDRIEVANTDGSMRTVLI 854
Score = 48.8 bits (111), Expect = 2e-05
Identities = 27/77 (35%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D+ ++ ++W D+ TIE A LD RKVL Q + +P G+ ++ +R I+WTDW +
Sbjct: 911 DYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQ-LPHPFGLTLYGER--IYWTDWQTKS 967
Query: 181 PKIEWAN-MDGTERSVL 228
I+ A+ + G +R L
Sbjct: 968 --IQSADRLTGLDRETL 982
Score = 48.4 bits (110), Expect = 2e-05
Identities = 26/74 (35%), Positives = 43/74 (58%), Gaps = 1/74 (1%)
Frame = +1
Query: 19 IFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
++WTD IE A +D R+V+ S N++ P G+A+ +++W D IE+
Sbjct: 873 MYWTDWGASPKIERAGMDASGRQVIIS-SNLTWPNGLAIDYGSQRLYWADAGMKT--IEF 929
Query: 196 ANMDGTERSVLLGS 237
A +DG++R VL+GS
Sbjct: 930 AGLDGSKRKVLIGS 943
Score = 47.2 bits (107), Expect = 5e-05
Identities = 19/66 (28%), Positives = 36/66 (54%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
N + +D + ++ +ADA + I+ DL+ T+ ++P+GL + +YW+DW+T
Sbjct: 1214 NGLTVDKASSQLLWADAHTERIEAADLNGANRHTLVSPVQHPYGLTLLDSYIYWTDWQTR 1273
Query: 435 KIEIID 452
I D
Sbjct: 1274 SIHRAD 1279
Score = 46.8 bits (106), Expect = 6e-05
Identities = 19/66 (28%), Positives = 36/66 (54%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
N + +D+ R+ + DA L I+ DL+ + + + + +PF L +YW+DW+T
Sbjct: 1518 NGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVGHVSHPFALTQQDRWIYWTDWQTK 1577
Query: 435 KIEIID 452
I+ +D
Sbjct: 1578 SIQRVD 1583
Score = 46.4 bits (105), Expect = 8e-05
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN 171
D++ R ++W D+K IE ANLD RK + S Q + +P I V ++WTDW+
Sbjct: 606 DYAGRRMYWVDAKHHVIERANLDGSHRKAVIS-QGLPHPFAITVF--EDSLYWTDWH 659
Score = 44.4 bits (100), Expect = 3e-04
Identities = 28/72 (38%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLD-TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
+FW+D I ANL+ + V +V+ + + +P G+AV K++WTD S +IE
Sbjct: 482 VFWSDVTLDRILRANLNGSNVEEVVST--GLESPGGLAVDWVHDKLYWTDSGTS--RIEV 537
Query: 196 ANMDGTERSVLL 231
AN+DG R VLL
Sbjct: 538 ANLDGAHRKVLL 549
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAINGDKLYWSDWRT 431
N + ID++ R+ + DA VI+ +L S + I++ +PF + + D LYW+DW T
Sbjct: 601 NGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHT 660
Query: 432 LKIEIIDTITQARGQI 479
I + T +I
Sbjct: 661 KSINSANKFTGKNQEI 676
Score = 37.1 bits (82), Expect = 0.051
Identities = 23/69 (33%), Positives = 40/69 (57%), Gaps = 5/69 (7%)
Frame = +3
Query: 255 NSVAIDWS--RDRVCFADAGLQVIKCIDLHSRQIE-TIAENCRYPFGLAING--DKLYWS 419
N++A+D+ R+ V ++D L I +L+ +E ++ P GLA++ DKLYW+
Sbjct: 469 NAIALDFHHRRELVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHDKLYWT 528
Query: 420 DWRTLKIEI 446
D T +IE+
Sbjct: 529 DSGTSRIEV 537
Score = 37.1 bits (82), Expect = 0.051
Identities = 26/78 (33%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
Frame = +3
Query: 237 PRCEASNSVAIDW-SRD-RVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAING-- 401
P + ++VA+DW SRD V + D I E + + + P GLAI+
Sbjct: 768 PLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGTGQEVVVDTSLESPAGLAIDWVT 827
Query: 402 DKLYWSDWRTLKIEIIDT 455
+KLYW+D T +IE+ +T
Sbjct: 828 NKLYWTDAGTDRIEVANT 845
Score = 36.3 bits (80), Expect = 0.089
Identities = 19/70 (27%), Positives = 37/70 (52%), Gaps = 4/70 (5%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIA-ENCRYPFGLAIN--GDKLYW 416
E+ +A+DW D++ + D+G I+ +L + + +N P +A++ +YW
Sbjct: 511 ESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQNLEKPRAIALHPMEGTIYW 570
Query: 417 SDW-RTLKIE 443
+DW T +IE
Sbjct: 571 TDWGNTPRIE 580
Score = 34.3 bits (75), Expect = 0.36
Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAIN--GDKLYW 416
E+ +AIDW +++ + DAG I+ + S + I EN P + + G +YW
Sbjct: 816 ESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGYMYW 875
Query: 417 SDW 425
+DW
Sbjct: 876 TDW 878
Score = 34.3 bits (75), Expect = 0.36
Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Frame = +1
Query: 16 NIFWTDSKKLTIEVANLDTKVRKVLFSVQNIS--NPRGIAVHPQRGKIFWTDWNRSNPKI 189
N F ++++ I + +LD + NI+ N + V PQ GK++W+D + +I
Sbjct: 1048 NSFLIFARRIDIRMVSLDIPYFADVVVPINITMKNTIAVGVDPQEGKVYWSD--STLHRI 1105
Query: 190 EWANMDGTERSVLL 231
AN+DG++ ++
Sbjct: 1106 SRANLDGSQHEDII 1119
Score = 31.5 bits (68), Expect = 2.5
Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 3/66 (4%)
Frame = +3
Query: 258 SVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAIN--GDKLYWSDWR 428
+V +D +V ++D+ L I +L Q E I + GLA++ G K+YW+D
Sbjct: 1085 AVGVDPQEGKVYWSDSTLHRISRANLDGSQHEDIITTGLQTTDGLAVDAIGRKVYWTDTG 1144
Query: 429 TLKIEI 446
T +IE+
Sbjct: 1145 TNRIEV 1150
>AB011540-1|BAA32468.1| 1576|Homo sapiens MEGF7 protein.
Length = 1576
Score = 88.2 bits (209), Expect = 2e-17
Identities = 40/79 (50%), Positives = 55/79 (69%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ARN++WTD+ + TIE + LD RKVL + ++ PR IAV P++G +FWTDW
Sbjct: 1107 DWVARNLYWTDTGRNTIEASRLDGSCRKVLIN-NSLDEPRAIAVFPRKGYLFWTDWGHI- 1164
Query: 181 PKIEWANMDGTERSVLLGS 237
KIE AN+DG+ER VL+ +
Sbjct: 1165 AKIERANLDGSERKVLINT 1183
Score = 81.8 bits (193), Expect = 2e-15
Identities = 38/76 (50%), Positives = 50/76 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++WTDS IEVANLD RKVL QN+ PR IA+HP G I+WTDW +
Sbjct: 190 DWVHDKLYWTDSGTSRIEVANLDGAHRKVLLW-QNLEKPRAIALHPMEGTIYWTDWG-NT 247
Query: 181 PKIEWANMDGTERSVL 228
P+IE ++MDG+ R ++
Sbjct: 248 PRIEASSMDGSGRRII 263
Score = 74.9 bits (176), Expect = 2e-13
Identities = 36/79 (45%), Positives = 47/79 (59%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++WTD+ IEVAN D +R VL +N+ PR I V P G ++WTDW S
Sbjct: 495 DWVTNKLYWTDAGTDRIEVANTDGSMRTVLIW-ENLDRPRDIVVEPMGGYMYWTDWGAS- 552
Query: 181 PKIEWANMDGTERSVLLGS 237
PKIE A MD + R V++ S
Sbjct: 553 PKIERAGMDASGRQVIISS 571
Score = 73.3 bits (172), Expect = 6e-13
Identities = 34/79 (43%), Positives = 52/79 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D R ++WTD+ IEV NLD +RKVL QN+ +PR I ++ + G ++WTDW N
Sbjct: 803 DAIGRKVYWTDTGTNRIEVGNLDGSMRKVLV-WQNLDSPRAIVLYHEMGFMYWTDWG-EN 860
Query: 181 PKIEWANMDGTERSVLLGS 237
K+E + MDG++R+VL+ +
Sbjct: 861 AKLERSGMDGSDRAVLINN 879
Score = 59.3 bits (137), Expect = 1e-08
Identities = 26/70 (37%), Positives = 44/70 (62%), Gaps = 1/70 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAINGDKLYWSDWRT 431
N +AID+ R+ +ADAG++ I+ L S++ I +PFGL + G+++YW+DW+T
Sbjct: 577 NGLAIDYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIYWTDWQT 636
Query: 432 LKIEIIDTIT 461
I+ D +T
Sbjct: 637 KSIQSADRLT 646
Score = 49.6 bits (113), Expect = 9e-06
Identities = 27/79 (34%), Positives = 45/79 (56%), Gaps = 2/79 (2%)
Frame = +1
Query: 1 DWSARN--IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
DW +R+ ++WTD TI A D ++V+ ++ +P G+A+ K++WTD
Sbjct: 450 DWDSRDDHVYWTDVSTDTISRAKWDGTGQEVVVDT-SLESPAGLAIDWVTNKLYWTD--A 506
Query: 175 SNPKIEWANMDGTERSVLL 231
+IE AN DG+ R+VL+
Sbjct: 507 GTDRIEVANTDGSMRTVLI 525
Score = 48.8 bits (111), Expect = 2e-05
Identities = 27/77 (35%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D+ ++ ++W D+ TIE A LD RKVL Q + +P G+ ++ +R I+WTDW +
Sbjct: 582 DYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQ-LPHPFGLTLYGER--IYWTDWQTKS 638
Query: 181 PKIEWAN-MDGTERSVL 228
I+ A+ + G +R L
Sbjct: 639 --IQSADRLTGLDRETL 653
Score = 48.4 bits (110), Expect = 2e-05
Identities = 26/74 (35%), Positives = 43/74 (58%), Gaps = 1/74 (1%)
Frame = +1
Query: 19 IFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
++WTD IE A +D R+V+ S N++ P G+A+ +++W D IE+
Sbjct: 544 MYWTDWGASPKIERAGMDASGRQVIIS-SNLTWPNGLAIDYGSQRLYWADAGMKT--IEF 600
Query: 196 ANMDGTERSVLLGS 237
A +DG++R VL+GS
Sbjct: 601 AGLDGSKRKVLIGS 614
Score = 47.2 bits (107), Expect = 5e-05
Identities = 19/66 (28%), Positives = 36/66 (54%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
N + +D + ++ +ADA + I+ DL+ T+ ++P+GL + +YW+DW+T
Sbjct: 885 NGLTVDKASSQLLWADAHTERIEAADLNGANRHTLVSPVQHPYGLTLLDSYIYWTDWQTR 944
Query: 435 KIEIID 452
I D
Sbjct: 945 SIHRAD 950
Score = 46.8 bits (106), Expect = 6e-05
Identities = 19/66 (28%), Positives = 36/66 (54%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
N + +D+ R+ + DA L I+ DL+ + + + + +PF L +YW+DW+T
Sbjct: 1189 NGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVGHVSHPFALTQQDRWIYWTDWQTK 1248
Query: 435 KIEIID 452
I+ +D
Sbjct: 1249 SIQRVD 1254
Score = 46.4 bits (105), Expect = 8e-05
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN 171
D++ R ++W D+K IE ANLD RK + S Q + +P I V ++WTDW+
Sbjct: 277 DYAGRRMYWVDAKHHVIERANLDGSHRKAVIS-QGLPHPFAITVF--EDSLYWTDWH 330
Score = 44.4 bits (100), Expect = 3e-04
Identities = 28/72 (38%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLD-TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
+FW+D I ANL+ + V +V+ + + +P G+AV K++WTD S +IE
Sbjct: 153 VFWSDVTLDRILRANLNGSNVEEVVST--GLESPGGLAVDWVHDKLYWTDSGTS--RIEV 208
Query: 196 ANMDGTERSVLL 231
AN+DG R VLL
Sbjct: 209 ANLDGAHRKVLL 220
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAINGDKLYWSDWRT 431
N + ID++ R+ + DA VI+ +L S + I++ +PF + + D LYW+DW T
Sbjct: 272 NGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHT 331
Query: 432 LKIEIIDTITQARGQI 479
I + T +I
Sbjct: 332 KSINSANKFTGKNQEI 347
Score = 37.1 bits (82), Expect = 0.051
Identities = 23/69 (33%), Positives = 40/69 (57%), Gaps = 5/69 (7%)
Frame = +3
Query: 255 NSVAIDWS--RDRVCFADAGLQVIKCIDLHSRQIE-TIAENCRYPFGLAING--DKLYWS 419
N++A+D+ R+ V ++D L I +L+ +E ++ P GLA++ DKLYW+
Sbjct: 140 NAIALDFHHRRELVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHDKLYWT 199
Query: 420 DWRTLKIEI 446
D T +IE+
Sbjct: 200 DSGTSRIEV 208
Score = 37.1 bits (82), Expect = 0.051
Identities = 26/78 (33%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
Frame = +3
Query: 237 PRCEASNSVAIDW-SRD-RVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAING-- 401
P + ++VA+DW SRD V + D I E + + + P GLAI+
Sbjct: 439 PLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGTGQEVVVDTSLESPAGLAIDWVT 498
Query: 402 DKLYWSDWRTLKIEIIDT 455
+KLYW+D T +IE+ +T
Sbjct: 499 NKLYWTDAGTDRIEVANT 516
Score = 36.3 bits (80), Expect = 0.089
Identities = 19/70 (27%), Positives = 37/70 (52%), Gaps = 4/70 (5%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIA-ENCRYPFGLAIN--GDKLYW 416
E+ +A+DW D++ + D+G I+ +L + + +N P +A++ +YW
Sbjct: 182 ESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQNLEKPRAIALHPMEGTIYW 241
Query: 417 SDW-RTLKIE 443
+DW T +IE
Sbjct: 242 TDWGNTPRIE 251
Score = 34.3 bits (75), Expect = 0.36
Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAIN--GDKLYW 416
E+ +AIDW +++ + DAG I+ + S + I EN P + + G +YW
Sbjct: 487 ESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGYMYW 546
Query: 417 SDW 425
+DW
Sbjct: 547 TDW 549
Score = 34.3 bits (75), Expect = 0.36
Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Frame = +1
Query: 16 NIFWTDSKKLTIEVANLDTKVRKVLFSVQNIS--NPRGIAVHPQRGKIFWTDWNRSNPKI 189
N F ++++ I + +LD + NI+ N + V PQ GK++W+D + +I
Sbjct: 719 NSFLIFARRIDIRMVSLDIPYFADVVVPINITMKNTIAVGVDPQEGKVYWSD--STLHRI 776
Query: 190 EWANMDGTERSVLL 231
AN+DG++ ++
Sbjct: 777 SRANLDGSQHEDII 790
Score = 31.5 bits (68), Expect = 2.5
Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 3/66 (4%)
Frame = +3
Query: 258 SVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAIN--GDKLYWSDWR 428
+V +D +V ++D+ L I +L Q E I + GLA++ G K+YW+D
Sbjct: 756 AVGVDPQEGKVYWSDSTLHRISRANLDGSQHEDIITTGLQTTDGLAVDAIGRKVYWTDTG 815
Query: 429 TLKIEI 446
T +IE+
Sbjct: 816 TNRIEV 821
>AF283321-1|AAK52433.1| 1611|Homo sapiens low density lipoprotein
receptor-related protein 5 protein.
Length = 1611
Score = 87.4 bits (207), Expect = 4e-17
Identities = 40/79 (50%), Positives = 54/79 (68%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ARN++WTD+ IEV L+ RK+L S +++ PR IA+HP G ++WTDW N
Sbjct: 424 DWVARNLYWTDTGTDRIEVTRLNGTSRKILVS-EDLDEPRAIALHPVMGLMYWTDWG-EN 481
Query: 181 PKIEWANMDGTERSVLLGS 237
PKIE AN+DG ER VL+ +
Sbjct: 482 PKIECANLDGQERRVLVNA 500
Score = 81.8 bits (193), Expect = 2e-15
Identities = 39/85 (45%), Positives = 56/85 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW + ++WTDS+ IEVANL+ RKVLF Q++ PR IA+ P G ++WTDW +
Sbjct: 116 DWVGKKLYWTDSETNRIEVANLNGTSRKVLF-WQDLDQPRAIALDPAHGYMYWTDWGET- 173
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
P+IE A MDG+ R +++ S D+ P
Sbjct: 174 PRIERAGMDGSTRKIIVDS-DIYWP 197
Score = 68.9 bits (161), Expect = 1e-11
Identities = 32/77 (41%), Positives = 48/77 (62%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW +N++W D+ IEVA LD + R+VL +++ NPR +A+ P +G I+WT+W
Sbjct: 726 DWMGKNLYWADTGTNRIEVARLDGQFRQVLV-WRDLDNPRSLALDPTKGYIYWTEWG-GK 783
Query: 181 PKIEWANMDGTERSVLL 231
P+I A MDGT L+
Sbjct: 784 PRIVRAFMDGTNCMTLV 800
Score = 54.8 bits (126), Expect = 2e-07
Identities = 34/86 (39%), Positives = 51/86 (59%), Gaps = 1/86 (1%)
Frame = +1
Query: 19 IFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
++WTD + IE ANLD + R+VL + ++ P G+A+ Q GK++W D KIE
Sbjct: 473 MYWTDWGENPKIECANLDGQERRVLVNA-SLGWPNGLALDLQEGKLYWGD--AKTDKIEV 529
Query: 196 ANMDGTERSVLLGSPDVKLPTLWPST 273
N+DGT+R LL + KLP ++ T
Sbjct: 530 INVDGTKRRTLL---EDKLPHIFGFT 552
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/76 (36%), Positives = 39/76 (51%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +R +FWT TI V L + V+ PR I V+ +RG +++T+
Sbjct: 1032 DIYSRTLFWTCEATNTINVHRLSGEAMGVVLRGDR-DKPRAIVVNAERGYLYFTNMQDRA 1090
Query: 181 PKIEWANMDGTERSVL 228
KIE A +DGTER VL
Sbjct: 1091 AKIERAALDGTEREVL 1106
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/63 (34%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAINGDKLYWSDWRT 431
N + ID ++ +ADA L I +L + + E + +PF L ++GD LYW+DW+T
Sbjct: 198 NGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPFALTLSGDTLYWTDWQT 257
Query: 432 LKI 440
I
Sbjct: 258 RSI 260
Score = 46.4 bits (105), Expect = 8e-05
Identities = 20/67 (29%), Positives = 37/67 (55%)
Frame = +3
Query: 252 SNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRT 431
+N + ID++ R+ + D +I+ ++ ++ IA++ +PFGL D +YW+DW
Sbjct: 806 ANDLTIDYADQRLYWTDLDTNMIESSNMLGQERVVIADDLPHPFGLTQYSDYIYWTDWNL 865
Query: 432 LKIEIID 452
IE D
Sbjct: 866 HSIERAD 872
Score = 43.2 bits (97), Expect = 8e-04
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN-CRYPFGLAINGDKLYWSDWRT 431
N +A+D ++ + DA I+ I++ + T+ E+ + FG + GD +YW+DW+
Sbjct: 506 NGLALDLQEGKLYWGDAKTDKIEVINVDGTKRRTLLEDKLPHIFGFTLLGDFIYWTDWQR 565
Query: 432 LKIEIIDTITQARGQI 479
IE + + +R I
Sbjct: 566 RSIERVHKVKASRDVI 581
Score = 42.7 bits (96), Expect = 0.001
Identities = 26/79 (32%), Positives = 42/79 (53%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
++WTD + I A LD + L + + I++P GIAV ++WTD +IE
Sbjct: 387 VYWTDDEVRAIRRAYLDGSGAQTLVNTE-INDPDGIAVDWVARNLYWTD--TGTDRIEVT 443
Query: 199 NMDGTERSVLLGSPDVKLP 255
++GT R +L+ S D+ P
Sbjct: 444 RLNGTSRKILV-SEDLDEP 461
Score = 37.9 bits (84), Expect = 0.029
Identities = 25/73 (34%), Positives = 42/73 (57%), Gaps = 3/73 (4%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLD---TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKI 189
++WTD + I+ L+ V+ V+ S + +P G+A K++WTD + +N +I
Sbjct: 77 VYWTDVSEEAIKQTYLNQTGAAVQNVVIS--GLVSPDGLACDWVGKKLYWTD-SETN-RI 132
Query: 190 EWANMDGTERSVL 228
E AN++GT R VL
Sbjct: 133 EVANLNGTSRKVL 145
Score = 37.1 bits (82), Expect = 0.051
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Frame = +1
Query: 19 IFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
++WTD + IE A +D RK++ +I P G+ + + K++W D S I
Sbjct: 165 MYWTDWGETPRIERAGMDGSTRKIIVD-SDIYWPNGLTIDLEEQKLYWADAKLS--FIHR 221
Query: 196 ANMDGTER-SVLLGS 237
AN+DG+ R V+ GS
Sbjct: 222 ANLDGSFRQKVVEGS 236
Score = 37.1 bits (82), Expect = 0.051
Identities = 19/68 (27%), Positives = 37/68 (54%), Gaps = 3/68 (4%)
Frame = +3
Query: 252 SNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAIN--GDKLYWSD 422
++++ D S + + + D L+ I ++ +E + E YP G+A++ G LYW+D
Sbjct: 677 ASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVVEFGLDYPEGMAVDWMGKNLYWAD 736
Query: 423 WRTLKIEI 446
T +IE+
Sbjct: 737 TGTNRIEV 744
Score = 37.1 bits (82), Expect = 0.051
Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D++ + ++WTD IE +N+ + R V+ ++ +P G+ + I+WTDWN +
Sbjct: 812 DYADQRLYWTDLDTNMIESSNMLGQERVVI--ADDLPHPFGLTQYSDY--IYWTDWNLHS 867
Query: 181 PKIEWAN-MDGTERSVLLGSPDVKLPTL 261
IE A+ G R+++ G D + L
Sbjct: 868 --IERADKTSGRNRTLIQGHLDFVMDIL 893
Score = 35.1 bits (77), Expect = 0.21
Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
Frame = +3
Query: 258 SVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAINGDKLYWSDWRTL 434
++ +D + ++ + DA L+ I+ DL T+ + N P GL I G LYW D +
Sbjct: 1116 ALVVDNTLGKLFWVDADLKRIESCDLSGANRLTLEDANIVQPLGLTILGKHLYWIDRQQQ 1175
Query: 435 KIEIIDTIT 461
IE ++ T
Sbjct: 1176 MIERVEKTT 1184
Score = 32.7 bits (71), Expect = 1.1
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D ++W D+K IEV N+D R+ L + + G + I+WTDW R +
Sbjct: 511 DLQEGKLYWGDAKTDKIEVINVDGTKRRTLLE-DKLPHIFGFTL--LGDFIYWTDWQRRS 567
Query: 181 PKIEWANMDGTERSVLLGS-PDV 246
IE + R V++ PD+
Sbjct: 568 --IERVHKVKASRDVIIDQLPDL 588
Score = 31.5 bits (68), Expect = 2.5
Identities = 16/56 (28%), Positives = 29/56 (51%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDW 168
D + ++W D+K I ANLD R+ + ++++P A+ ++WTDW
Sbjct: 203 DLEEQKLYWADAKLSFIHRANLDGSFRQKVVE-GSLTHP--FALTLSGDTLYWTDW 255
>AF077820-1|AAC72791.1| 1615|Homo sapiens LDL receptor member LR3
protein.
Length = 1615
Score = 87.4 bits (207), Expect = 4e-17
Identities = 40/79 (50%), Positives = 54/79 (68%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ARN++WTD+ IEV L+ RK+L S +++ PR IA+HP G ++WTDW N
Sbjct: 424 DWVARNLYWTDTGTDRIEVTRLNGTSRKILVS-EDLDEPRAIALHPVMGLMYWTDWG-EN 481
Query: 181 PKIEWANMDGTERSVLLGS 237
PKIE AN+DG ER VL+ +
Sbjct: 482 PKIECANLDGQERRVLVNA 500
Score = 81.8 bits (193), Expect = 2e-15
Identities = 39/85 (45%), Positives = 56/85 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW + ++WTDS+ IEVANL+ RKVLF Q++ PR IA+ P G ++WTDW +
Sbjct: 116 DWVGKKLYWTDSETNRIEVANLNGTSRKVLF-WQDLDQPRAIALDPAHGYMYWTDWGET- 173
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
P+IE A MDG+ R +++ S D+ P
Sbjct: 174 PRIERAGMDGSTRKIIVDS-DIYWP 197
Score = 68.9 bits (161), Expect = 1e-11
Identities = 32/77 (41%), Positives = 48/77 (62%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW +N++W D+ IEVA LD + R+VL +++ NPR +A+ P +G I+WT+W
Sbjct: 726 DWMGKNLYWADTGTNRIEVARLDGQFRQVLV-WRDLDNPRSLALDPTKGYIYWTEWG-GK 783
Query: 181 PKIEWANMDGTERSVLL 231
P+I A MDGT L+
Sbjct: 784 PRIVRAFMDGTNCMTLV 800
Score = 54.8 bits (126), Expect = 2e-07
Identities = 34/86 (39%), Positives = 51/86 (59%), Gaps = 1/86 (1%)
Frame = +1
Query: 19 IFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
++WTD + IE ANLD + R+VL + ++ P G+A+ Q GK++W D KIE
Sbjct: 473 MYWTDWGENPKIECANLDGQERRVLVNA-SLGWPNGLALDLQEGKLYWGD--AKTDKIEV 529
Query: 196 ANMDGTERSVLLGSPDVKLPTLWPST 273
N+DGT+R LL + KLP ++ T
Sbjct: 530 INVDGTKRRTLL---EDKLPHIFGFT 552
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/76 (36%), Positives = 39/76 (51%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +R +FWT TI V L + V+ PR I V+ +RG +++T+
Sbjct: 1032 DIYSRTLFWTCEATNTINVHRLSGEAMGVVLRGDR-DKPRAIVVNAERGYLYFTNMQDRA 1090
Query: 181 PKIEWANMDGTERSVL 228
KIE A +DGTER VL
Sbjct: 1091 AKIERAALDGTEREVL 1106
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/63 (34%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAINGDKLYWSDWRT 431
N + ID ++ +ADA L I +L + + E + +PF L ++GD LYW+DW+T
Sbjct: 198 NGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPFALTLSGDTLYWTDWQT 257
Query: 432 LKI 440
I
Sbjct: 258 RSI 260
Score = 46.4 bits (105), Expect = 8e-05
Identities = 20/67 (29%), Positives = 37/67 (55%)
Frame = +3
Query: 252 SNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRT 431
+N + ID++ R+ + D +I+ ++ ++ IA++ +PFGL D +YW+DW
Sbjct: 806 ANDLTIDYADQRLYWTDLDTNMIESSNMLGQERVVIADDLPHPFGLTQYSDYIYWTDWNL 865
Query: 432 LKIEIID 452
IE D
Sbjct: 866 HSIERAD 872
Score = 43.2 bits (97), Expect = 8e-04
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN-CRYPFGLAINGDKLYWSDWRT 431
N +A+D ++ + DA I+ I++ + T+ E+ + FG + GD +YW+DW+
Sbjct: 506 NGLALDLQEGKLYWGDAKTDKIEVINVDGTKRRTLLEDKLPHIFGFTLLGDFIYWTDWQR 565
Query: 432 LKIEIIDTITQARGQI 479
IE + + +R I
Sbjct: 566 RSIERVHKVKASRDVI 581
Score = 42.7 bits (96), Expect = 0.001
Identities = 26/79 (32%), Positives = 42/79 (53%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
++WTD + I A LD + L + + I++P GIAV ++WTD +IE
Sbjct: 387 VYWTDDEVRAIRRAYLDGSGAQTLVNTE-INDPDGIAVDWVARNLYWTD--TGTDRIEVT 443
Query: 199 NMDGTERSVLLGSPDVKLP 255
++GT R +L+ S D+ P
Sbjct: 444 RLNGTSRKILV-SEDLDEP 461
Score = 37.9 bits (84), Expect = 0.029
Identities = 25/73 (34%), Positives = 42/73 (57%), Gaps = 3/73 (4%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLD---TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKI 189
++WTD + I+ L+ V+ V+ S + +P G+A K++WTD + +N +I
Sbjct: 77 VYWTDVSEEAIKQTYLNQTGAAVQNVVIS--GLVSPDGLACDWVGKKLYWTD-SETN-RI 132
Query: 190 EWANMDGTERSVL 228
E AN++GT R VL
Sbjct: 133 EVANLNGTSRKVL 145
Score = 37.1 bits (82), Expect = 0.051
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Frame = +1
Query: 19 IFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
++WTD + IE A +D RK++ +I P G+ + + K++W D S I
Sbjct: 165 MYWTDWGETPRIERAGMDGSTRKIIVD-SDIYWPNGLTIDLEEQKLYWADAKLS--FIHR 221
Query: 196 ANMDGTER-SVLLGS 237
AN+DG+ R V+ GS
Sbjct: 222 ANLDGSFRQKVVEGS 236
Score = 37.1 bits (82), Expect = 0.051
Identities = 19/68 (27%), Positives = 37/68 (54%), Gaps = 3/68 (4%)
Frame = +3
Query: 252 SNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAIN--GDKLYWSD 422
++++ D S + + + D L+ I ++ +E + E YP G+A++ G LYW+D
Sbjct: 677 ASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVVEFGLDYPEGMAVDWMGKNLYWAD 736
Query: 423 WRTLKIEI 446
T +IE+
Sbjct: 737 TGTNRIEV 744
Score = 37.1 bits (82), Expect = 0.051
Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D++ + ++WTD IE +N+ + R V+ ++ +P G+ + I+WTDWN +
Sbjct: 812 DYADQRLYWTDLDTNMIESSNMLGQERVVI--ADDLPHPFGLTQYSDY--IYWTDWNLHS 867
Query: 181 PKIEWAN-MDGTERSVLLGSPDVKLPTL 261
IE A+ G R+++ G D + L
Sbjct: 868 --IERADKTSGRNRTLIQGHLDFVMDIL 893
Score = 35.1 bits (77), Expect = 0.21
Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
Frame = +3
Query: 258 SVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAINGDKLYWSDWRTL 434
++ +D + ++ + DA L+ I+ DL T+ + N P GL I G LYW D +
Sbjct: 1116 ALVVDNTLGKLFWVDADLKRIESCDLSGANRLTLEDANIVQPLGLTILGKHLYWIDRQQQ 1175
Query: 435 KIEIIDTIT 461
IE ++ T
Sbjct: 1176 MIERVEKTT 1184
Score = 32.7 bits (71), Expect = 1.1
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D ++W D+K IEV N+D R+ L + + G + I+WTDW R +
Sbjct: 511 DLQEGKLYWGDAKTDKIEVINVDGTKRRTLLE-DKLPHIFGFTL--LGDFIYWTDWQRRS 567
Query: 181 PKIEWANMDGTERSVLLGS-PDV 246
IE + R V++ PD+
Sbjct: 568 --IERVHKVKASRDVIIDQLPDL 588
Score = 31.5 bits (68), Expect = 2.5
Identities = 16/56 (28%), Positives = 29/56 (51%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDW 168
D + ++W D+K I ANLD R+ + ++++P A+ ++WTDW
Sbjct: 203 DLEEQKLYWADAKLSFIHRANLDGSFRQKVVE-GSLTHP--FALTLSGDTLYWTDW 255
>AF064548-1|AAC36467.1| 1615|Homo sapiens low-density lipoprotein
receptor-related protein 5 protein.
Length = 1615
Score = 87.4 bits (207), Expect = 4e-17
Identities = 40/79 (50%), Positives = 54/79 (68%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ARN++WTD+ IEV L+ RK+L S +++ PR IA+HP G ++WTDW N
Sbjct: 424 DWVARNLYWTDTGTDRIEVTRLNGTSRKILVS-EDLDEPRAIALHPVMGLMYWTDWG-EN 481
Query: 181 PKIEWANMDGTERSVLLGS 237
PKIE AN+DG ER VL+ +
Sbjct: 482 PKIECANLDGQERRVLVNA 500
Score = 81.8 bits (193), Expect = 2e-15
Identities = 39/85 (45%), Positives = 56/85 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW + ++WTDS+ IEVANL+ RKVLF Q++ PR IA+ P G ++WTDW +
Sbjct: 116 DWVGKKLYWTDSETNRIEVANLNGTSRKVLF-WQDLDQPRAIALDPAHGYMYWTDWGET- 173
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
P+IE A MDG+ R +++ S D+ P
Sbjct: 174 PRIERAGMDGSTRKIIVDS-DIYWP 197
Score = 68.9 bits (161), Expect = 1e-11
Identities = 32/77 (41%), Positives = 48/77 (62%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW +N++W D+ IEVA LD + R+VL +++ NPR +A+ P +G I+WT+W
Sbjct: 726 DWMGKNLYWADTGTNRIEVARLDGQFRQVLV-WRDLDNPRSLALDPTKGYIYWTEWG-GK 783
Query: 181 PKIEWANMDGTERSVLL 231
P+I A MDGT L+
Sbjct: 784 PRIVRAFMDGTNCMTLV 800
Score = 54.8 bits (126), Expect = 2e-07
Identities = 34/86 (39%), Positives = 51/86 (59%), Gaps = 1/86 (1%)
Frame = +1
Query: 19 IFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
++WTD + IE ANLD + R+VL + ++ P G+A+ Q GK++W D KIE
Sbjct: 473 MYWTDWGENPKIECANLDGQERRVLVNA-SLGWPNGLALDLQEGKLYWGD--AKTDKIEV 529
Query: 196 ANMDGTERSVLLGSPDVKLPTLWPST 273
N+DGT+R LL + KLP ++ T
Sbjct: 530 INVDGTKRRTLL---EDKLPHIFGFT 552
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/76 (36%), Positives = 39/76 (51%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +R +FWT TI V L + V+ PR I V+ +RG +++T+
Sbjct: 1032 DIYSRTLFWTCEATNTINVHRLSGEAMGVVLRGDR-DKPRAIVVNAERGYLYFTNMQDRA 1090
Query: 181 PKIEWANMDGTERSVL 228
KIE A +DGTER VL
Sbjct: 1091 AKIERAALDGTEREVL 1106
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/63 (34%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAINGDKLYWSDWRT 431
N + ID ++ +ADA L I +L + + E + +PF L ++GD LYW+DW+T
Sbjct: 198 NGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPFALTLSGDTLYWTDWQT 257
Query: 432 LKI 440
I
Sbjct: 258 RSI 260
Score = 46.4 bits (105), Expect = 8e-05
Identities = 20/67 (29%), Positives = 37/67 (55%)
Frame = +3
Query: 252 SNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRT 431
+N + ID++ R+ + D +I+ ++ ++ IA++ +PFGL D +YW+DW
Sbjct: 806 ANDLTIDYADQRLYWTDLDTNMIESSNMLGQERVVIADDLPHPFGLTQYSDYIYWTDWNL 865
Query: 432 LKIEIID 452
IE D
Sbjct: 866 HSIERAD 872
Score = 43.2 bits (97), Expect = 8e-04
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN-CRYPFGLAINGDKLYWSDWRT 431
N +A+D ++ + DA I+ I++ + T+ E+ + FG + GD +YW+DW+
Sbjct: 506 NGLALDLQEGKLYWGDAKTDKIEVINVDGTKRRTLLEDKLPHIFGFTLLGDFIYWTDWQR 565
Query: 432 LKIEIIDTITQARGQI 479
IE + + +R I
Sbjct: 566 RSIERVHKVKASRDVI 581
Score = 42.7 bits (96), Expect = 0.001
Identities = 26/79 (32%), Positives = 42/79 (53%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
++WTD + I A LD + L + + I++P GIAV ++WTD +IE
Sbjct: 387 VYWTDDEVRAIRRAYLDGSGAQTLVNTE-INDPDGIAVDWVARNLYWTD--TGTDRIEVT 443
Query: 199 NMDGTERSVLLGSPDVKLP 255
++GT R +L+ S D+ P
Sbjct: 444 RLNGTSRKILV-SEDLDEP 461
Score = 37.9 bits (84), Expect = 0.029
Identities = 25/73 (34%), Positives = 42/73 (57%), Gaps = 3/73 (4%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLD---TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKI 189
++WTD + I+ L+ V+ V+ S + +P G+A K++WTD + +N +I
Sbjct: 77 VYWTDVSEEAIKQTYLNQTGAAVQNVVIS--GLVSPDGLACDWVGKKLYWTD-SETN-RI 132
Query: 190 EWANMDGTERSVL 228
E AN++GT R VL
Sbjct: 133 EVANLNGTSRKVL 145
Score = 37.1 bits (82), Expect = 0.051
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Frame = +1
Query: 19 IFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
++WTD + IE A +D RK++ +I P G+ + + K++W D S I
Sbjct: 165 MYWTDWGETPRIERAGMDGSTRKIIVD-SDIYWPNGLTIDLEEQKLYWADAKLS--FIHR 221
Query: 196 ANMDGTER-SVLLGS 237
AN+DG+ R V+ GS
Sbjct: 222 ANLDGSFRQKVVEGS 236
Score = 37.1 bits (82), Expect = 0.051
Identities = 19/68 (27%), Positives = 37/68 (54%), Gaps = 3/68 (4%)
Frame = +3
Query: 252 SNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAIN--GDKLYWSD 422
++++ D S + + + D L+ I ++ +E + E YP G+A++ G LYW+D
Sbjct: 677 ASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVVEFGLDYPEGMAVDWMGKNLYWAD 736
Query: 423 WRTLKIEI 446
T +IE+
Sbjct: 737 TGTNRIEV 744
Score = 37.1 bits (82), Expect = 0.051
Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D++ + ++WTD IE +N+ + R V+ ++ +P G+ + I+WTDWN +
Sbjct: 812 DYADQRLYWTDLDTNMIESSNMLGQERVVI--ADDLPHPFGLTQYSDY--IYWTDWNLHS 867
Query: 181 PKIEWAN-MDGTERSVLLGSPDVKLPTL 261
IE A+ G R+++ G D + L
Sbjct: 868 --IERADKTSGRNRTLIQGHLDFVMDIL 893
Score = 35.1 bits (77), Expect = 0.21
Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
Frame = +3
Query: 258 SVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAINGDKLYWSDWRTL 434
++ +D + ++ + DA L+ I+ DL T+ + N P GL I G LYW D +
Sbjct: 1116 ALVVDNTLGKLFWVDADLKRIESCDLSGANRLTLEDANIVQPLGLTILGKHLYWIDRQQQ 1175
Query: 435 KIEIIDTIT 461
IE ++ T
Sbjct: 1176 MIERVEKTT 1184
Score = 32.7 bits (71), Expect = 1.1
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D ++W D+K IEV N+D R+ L + + G + I+WTDW R +
Sbjct: 511 DLQEGKLYWGDAKTDKIEVINVDGTKRRTLLE-DKLPHIFGFTL--LGDFIYWTDWQRRS 567
Query: 181 PKIEWANMDGTERSVLLGS-PDV 246
IE + R V++ PD+
Sbjct: 568 --IERVHKVKASRDVIIDQLPDL 588
Score = 31.5 bits (68), Expect = 2.5
Identities = 16/56 (28%), Positives = 29/56 (51%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDW 168
D + ++W D+K I ANLD R+ + ++++P A+ ++WTDW
Sbjct: 203 DLEEQKLYWADAKLSFIHRANLDGSFRQKVVE-GSLTHP--FALTLSGDTLYWTDW 255
>AB017498-1|BAA33051.1| 1615|Homo sapiens Lipoprotein Receptor
Related Protein 5 protein.
Length = 1615
Score = 87.4 bits (207), Expect = 4e-17
Identities = 40/79 (50%), Positives = 54/79 (68%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ARN++WTD+ IEV L+ RK+L S +++ PR IA+HP G ++WTDW N
Sbjct: 424 DWVARNLYWTDTGTDRIEVTRLNGTSRKILVS-EDLDEPRAIALHPVMGLMYWTDWG-EN 481
Query: 181 PKIEWANMDGTERSVLLGS 237
PKIE AN+DG ER VL+ +
Sbjct: 482 PKIECANLDGQERRVLVNA 500
Score = 81.8 bits (193), Expect = 2e-15
Identities = 39/85 (45%), Positives = 56/85 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW + ++WTDS+ IEVANL+ RKVLF Q++ PR IA+ P G ++WTDW +
Sbjct: 116 DWVGKKLYWTDSETNRIEVANLNGTSRKVLF-WQDLDQPRAIALDPAHGYMYWTDWGET- 173
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
P+IE A MDG+ R +++ S D+ P
Sbjct: 174 PRIERAGMDGSTRKIIVDS-DIYWP 197
Score = 68.9 bits (161), Expect = 1e-11
Identities = 32/77 (41%), Positives = 48/77 (62%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW +N++W D+ IEVA LD + R+VL +++ NPR +A+ P +G I+WT+W
Sbjct: 726 DWMGKNLYWADTGTNRIEVARLDGQFRQVLV-WRDLDNPRSLALDPTKGYIYWTEWG-GK 783
Query: 181 PKIEWANMDGTERSVLL 231
P+I A MDGT L+
Sbjct: 784 PRIVRAFMDGTNCMTLV 800
Score = 54.8 bits (126), Expect = 2e-07
Identities = 34/86 (39%), Positives = 51/86 (59%), Gaps = 1/86 (1%)
Frame = +1
Query: 19 IFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
++WTD + IE ANLD + R+VL + ++ P G+A+ Q GK++W D KIE
Sbjct: 473 MYWTDWGENPKIECANLDGQERRVLVNA-SLGWPNGLALDLQEGKLYWGD--AKTDKIEV 529
Query: 196 ANMDGTERSVLLGSPDVKLPTLWPST 273
N+DGT+R LL + KLP ++ T
Sbjct: 530 INVDGTKRRTLL---EDKLPHIFGFT 552
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/76 (36%), Positives = 39/76 (51%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +R +FWT TI V L + V+ PR I V+ +RG +++T+
Sbjct: 1032 DIYSRTLFWTCEATNTINVHRLSGEAMGVVLRGDR-DKPRAIVVNAERGYLYFTNMQDRA 1090
Query: 181 PKIEWANMDGTERSVL 228
KIE A +DGTER VL
Sbjct: 1091 AKIERAALDGTEREVL 1106
Score = 46.8 bits (106), Expect = 6e-05
Identities = 22/63 (34%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAINGDKLYWSDWRT 431
N + ID ++ +ADA L I +L + + E + +PF L ++GD LYW+DW+T
Sbjct: 198 NGLTIDLEEQKLYWADAKLSFIHRANLDGSFRQKVVEGSLTHPFALTLSGDTLYWTDWQT 257
Query: 432 LKI 440
I
Sbjct: 258 RSI 260
Score = 46.4 bits (105), Expect = 8e-05
Identities = 20/67 (29%), Positives = 37/67 (55%)
Frame = +3
Query: 252 SNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRT 431
+N + ID++ R+ + D +I+ ++ ++ IA++ +PFGL D +YW+DW
Sbjct: 806 ANDLTIDYADQRLYWTDLDTNMIESSNMLGQERVVIADDLPHPFGLTQYSDYIYWTDWNL 865
Query: 432 LKIEIID 452
IE D
Sbjct: 866 HSIERAD 872
Score = 43.2 bits (97), Expect = 8e-04
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN-CRYPFGLAINGDKLYWSDWRT 431
N +A+D ++ + DA I+ I++ + T+ E+ + FG + GD +YW+DW+
Sbjct: 506 NGLALDLQEGKLYWGDAKTDKIEVINVDGTKRRTLLEDKLPHIFGFTLLGDFIYWTDWQR 565
Query: 432 LKIEIIDTITQARGQI 479
IE + + +R I
Sbjct: 566 RSIERVHKVKASRDVI 581
Score = 42.7 bits (96), Expect = 0.001
Identities = 26/79 (32%), Positives = 42/79 (53%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
++WTD + I A LD + L + + I++P GIAV ++WTD +IE
Sbjct: 387 VYWTDDEVRAIRRAYLDGSGAQTLVNTE-INDPDGIAVDWVARNLYWTD--TGTDRIEVT 443
Query: 199 NMDGTERSVLLGSPDVKLP 255
++GT R +L+ S D+ P
Sbjct: 444 RLNGTSRKILV-SEDLDEP 461
Score = 37.9 bits (84), Expect = 0.029
Identities = 25/73 (34%), Positives = 42/73 (57%), Gaps = 3/73 (4%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLD---TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKI 189
++WTD + I+ L+ V+ V+ S + +P G+A K++WTD + +N +I
Sbjct: 77 VYWTDVSEEAIKQTYLNQTGAAVQNVVIS--GLVSPDGLACDWVGKKLYWTD-SETN-RI 132
Query: 190 EWANMDGTERSVL 228
E AN++GT R VL
Sbjct: 133 EVANLNGTSRKVL 145
Score = 37.1 bits (82), Expect = 0.051
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Frame = +1
Query: 19 IFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
++WTD + IE A +D RK++ +I P G+ + + K++W D S I
Sbjct: 165 MYWTDWGETPRIERAGMDGSTRKIIVD-SDIYWPNGLTIDLEEQKLYWADAKLS--FIHR 221
Query: 196 ANMDGTER-SVLLGS 237
AN+DG+ R V+ GS
Sbjct: 222 ANLDGSFRQKVVEGS 236
Score = 37.1 bits (82), Expect = 0.051
Identities = 19/68 (27%), Positives = 37/68 (54%), Gaps = 3/68 (4%)
Frame = +3
Query: 252 SNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAIN--GDKLYWSD 422
++++ D S + + + D L+ I ++ +E + E YP G+A++ G LYW+D
Sbjct: 677 ASALDFDVSNNHIYWTDVSLKTISRAFMNGSSVEHVVEFGLDYPEGMAVDWMGKNLYWAD 736
Query: 423 WRTLKIEI 446
T +IE+
Sbjct: 737 TGTNRIEV 744
Score = 37.1 bits (82), Expect = 0.051
Identities = 25/88 (28%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D++ + ++WTD IE +N+ + R V+ ++ +P G+ + I+WTDWN +
Sbjct: 812 DYADQRLYWTDLDTNMIESSNMLGQERVVI--ADDLPHPFGLTQYSDY--IYWTDWNLHS 867
Query: 181 PKIEWAN-MDGTERSVLLGSPDVKLPTL 261
IE A+ G R+++ G D + L
Sbjct: 868 --IERADKTSGRNRTLIQGHLDFVMDIL 893
Score = 35.1 bits (77), Expect = 0.21
Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
Frame = +3
Query: 258 SVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAINGDKLYWSDWRTL 434
++ +D + ++ + DA L+ I+ DL T+ + N P GL I G LYW D +
Sbjct: 1116 ALVVDNTLGKLFWVDADLKRIESCDLSGANRLTLEDANIVQPLGLTILGKHLYWIDRQQQ 1175
Query: 435 KIEIIDTIT 461
IE ++ T
Sbjct: 1176 MIERVEKTT 1184
Score = 32.7 bits (71), Expect = 1.1
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D ++W D+K IEV N+D R+ L + + G + I+WTDW R +
Sbjct: 511 DLQEGKLYWGDAKTDKIEVINVDGTKRRTLLE-DKLPHIFGFTL--LGDFIYWTDWQRRS 567
Query: 181 PKIEWANMDGTERSVLLGS-PDV 246
IE + R V++ PD+
Sbjct: 568 --IERVHKVKASRDVIIDQLPDL 588
Score = 31.5 bits (68), Expect = 2.5
Identities = 16/56 (28%), Positives = 29/56 (51%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDW 168
D + ++W D+K I ANLD R+ + ++++P A+ ++WTDW
Sbjct: 203 DLEEQKLYWADAKLSFIHRANLDGSFRQKVVE-GSLTHP--FALTLSGDTLYWTDW 255
>D86425-1|BAA13087.1| 1376|Homo sapiens osteonidogen protein.
Length = 1376
Score = 84.2 bits (199), Expect = 3e-16
Identities = 42/85 (49%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D R ++WTDS IE A LD RKVLF ++ NPR IAV P RG ++WTDWNR
Sbjct: 1195 DHIRRTMYWTDSVLDKIESALLDGSERKVLFYT-DLVNPRAIAVDPIRGNLYWTDWNREA 1253
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
PKIE +++DG R +L+ + D+ LP
Sbjct: 1254 PKIETSSLDGENRRILINT-DIGLP 1277
Score = 44.4 bits (100), Expect = 3e-04
Identities = 26/76 (34%), Positives = 37/76 (48%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D R ++WTD TI A L+ + +P G+A+ R ++WTD
Sbjct: 1151 DCRERMVYWTDVAGRTISRAGLELGAEPETIVNSGLISPEGLAIDHIRRTMYWTD--SVL 1208
Query: 181 PKIEWANMDGTERSVL 228
KIE A +DG+ER VL
Sbjct: 1209 DKIESALLDGSERKVL 1224
Score = 40.3 bits (90), Expect = 0.005
Identities = 18/58 (31%), Positives = 27/58 (46%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWR 428
N + D +C+ADAG + ++C I N +YPF + D Y +DWR
Sbjct: 1278 NGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNNLKYPFSIVSYADHFYHTDWR 1335
>BC035608-1|AAH35608.1| 969|Homo sapiens NID2 protein protein.
Length = 969
Score = 84.2 bits (199), Expect = 3e-16
Identities = 42/85 (49%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D R ++WTDS IE A LD RKVLF ++ NPR IAV P RG ++WTDWNR
Sbjct: 788 DHIRRTMYWTDSVLDKIESALLDGSERKVLFYT-DLVNPRAIAVDPIRGNLYWTDWNREA 846
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
PKIE +++DG R +L+ + D+ LP
Sbjct: 847 PKIETSSLDGENRRILINT-DIGLP 870
Score = 44.4 bits (100), Expect = 3e-04
Identities = 26/76 (34%), Positives = 37/76 (48%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D R ++WTD TI A L+ + +P G+A+ R ++WTD
Sbjct: 744 DCRERMVYWTDVAGRTISRAGLELGAEPETIVNSGLISPEGLAIDHIRRTMYWTD--SVL 801
Query: 181 PKIEWANMDGTERSVL 228
KIE A +DG+ER VL
Sbjct: 802 DKIESALLDGSERKVL 817
Score = 40.3 bits (90), Expect = 0.005
Identities = 18/58 (31%), Positives = 27/58 (46%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWR 428
N + D +C+ADAG + ++C I N +YPF + D Y +DWR
Sbjct: 871 NGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNNLKYPFSIVSYADHFYHTDWR 928
>AJ223500-1|CAA11418.1| 1375|Homo sapiens nidogen-2 protein.
Length = 1375
Score = 84.2 bits (199), Expect = 3e-16
Identities = 42/85 (49%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D R ++WTDS IE A LD RKVLF ++ NPR IAV P RG ++WTDWNR
Sbjct: 1194 DHIRRTMYWTDSVLDKIESALLDGSERKVLFYT-DLVNPRAIAVDPIRGNLYWTDWNREA 1252
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
PKIE +++DG R +L+ + D+ LP
Sbjct: 1253 PKIETSSLDGENRRILINT-DIGLP 1276
Score = 44.4 bits (100), Expect = 3e-04
Identities = 26/76 (34%), Positives = 37/76 (48%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D R ++WTD TI A L+ + +P G+A+ R ++WTD
Sbjct: 1150 DCRERMVYWTDVAGRTISRAGLELGAEPETIVNSGLISPEGLAIDHIRRTMYWTD--SVL 1207
Query: 181 PKIEWANMDGTERSVL 228
KIE A +DG+ER VL
Sbjct: 1208 DKIESALLDGSERKVL 1223
Score = 40.3 bits (90), Expect = 0.005
Identities = 18/58 (31%), Positives = 27/58 (46%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWR 428
N + D +C+ADAG + ++C I N +YPF + D Y +DWR
Sbjct: 1277 NGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNNLKYPFSIVSYADHFYHTDWR 1334
>AB009799-1|BAA24112.1| 1376|Homo sapiens osteonidogen protein.
Length = 1376
Score = 84.2 bits (199), Expect = 3e-16
Identities = 42/85 (49%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D R ++WTDS IE A LD RKVLF ++ NPR IAV P RG ++WTDWNR
Sbjct: 1195 DHIRRTMYWTDSVLDKIESALLDGSERKVLFYT-DLVNPRAIAVDPIRGNLYWTDWNREA 1253
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
PKIE +++DG R +L+ + D+ LP
Sbjct: 1254 PKIETSSLDGENRRILINT-DIGLP 1277
Score = 44.4 bits (100), Expect = 3e-04
Identities = 26/76 (34%), Positives = 37/76 (48%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D R ++WTD TI A L+ + +P G+A+ R ++WTD
Sbjct: 1151 DCRERMVYWTDVAGRTISRAGLELGAEPETIVNSGLISPEGLAIDHIRRTMYWTD--SVL 1208
Query: 181 PKIEWANMDGTERSVL 228
KIE A +DG+ER VL
Sbjct: 1209 DKIESALLDGSERKVL 1224
Score = 40.3 bits (90), Expect = 0.005
Identities = 18/58 (31%), Positives = 27/58 (46%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWR 428
N + D +C+ADAG + ++C I N +YPF + D Y +DWR
Sbjct: 1278 NGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNNLKYPFSIVSYADHFYHTDWR 1335
>BC126405-1|AAI26406.1| 1613|Homo sapiens low density lipoprotein
receptor-related protein 6 protein.
Length = 1613
Score = 82.6 bits (195), Expect = 1e-15
Identities = 38/79 (48%), Positives = 51/79 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++WTDS+ IEV+NLD +RKVLF Q + PR IA+ P G ++WTDW
Sbjct: 103 DWLGEKLYWTDSETNRIEVSNLDGSLRKVLF-WQELDQPRAIALDPSSGFMYWTDWGEV- 160
Query: 181 PKIEWANMDGTERSVLLGS 237
PKIE A MDG+ R +++ S
Sbjct: 161 PKIERAGMDGSSRFIIINS 179
Score = 76.2 bits (179), Expect = 9e-14
Identities = 35/79 (44%), Positives = 52/79 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ARN++WTD+ IEV L+ +RK+L S +++ PR I + P G ++WTDW
Sbjct: 411 DWVARNLYWTDTGTDRIEVTRLNGTMRKILIS-EDLEEPRAIVLDPMVGYMYWTDWGEI- 468
Query: 181 PKIEWANMDGTERSVLLGS 237
PKIE A +DG++R VL+ +
Sbjct: 469 PKIERAALDGSDRVVLVNT 487
Score = 69.7 bits (163), Expect = 8e-12
Identities = 31/77 (40%), Positives = 51/77 (66%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW +N++W D+ IEV+ LD + R+VL +++ +PR +A+ P G ++WT+W
Sbjct: 713 DWLGKNLYWADTGTNRIEVSKLDGQHRQVLV-WKDLDSPRALALDPAEGFMYWTEWG-GK 770
Query: 181 PKIEWANMDGTERSVLL 231
PKI+ A MDG+ER+ L+
Sbjct: 771 PKIDRAAMDGSERTTLV 787
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/79 (36%), Positives = 44/79 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +R I+WT I V LD + V+ + PR + V+P++G +++T+ +
Sbjct: 1022 DIYSRYIYWTCEATNVINVTRLDGRSVGVVLKGEQ-DRPRAVVVNPEKGYMYFTNLQERS 1080
Query: 181 PKIEWANMDGTERSVLLGS 237
PKIE A +DGTER VL S
Sbjct: 1081 PKIERAALDGTEREVLFFS 1099
Score = 47.6 bits (108), Expect = 4e-05
Identities = 21/69 (30%), Positives = 37/69 (53%)
Frame = +3
Query: 237 PRCEASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYW 416
P +N + ID+++ R+ + D +I+ ++ E IA++ +PFGL D +YW
Sbjct: 788 PNVGRANGLTIDYAKRRLYWTDLDTNLIESSNMLGLNREVIADDLPHPFGLTQYQDYIYW 847
Query: 417 SDWRTLKIE 443
+DW IE
Sbjct: 848 TDWSRRSIE 856
Score = 44.8 bits (101), Expect = 3e-04
Identities = 29/72 (40%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Frame = +1
Query: 19 IFWTDSKKLT-IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
++WTD ++ IE A LD R VL + ++ P G+A+ GKI+W D KIE
Sbjct: 460 MYWTDWGEIPKIERAALDGSDRVVLVNT-SLGWPNGLALDYDEGKIYWGD--AKTDKIEV 516
Query: 196 ANMDGTERSVLL 231
N DGT R VL+
Sbjct: 517 MNTDGTGRRVLV 528
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/88 (30%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D++ R ++WTD IE +N+ R+V+ ++ +P G+ + + I+WTDW+R +
Sbjct: 799 DYAKRRLYWTDLDTNLIESSNMLGLNREVI--ADDLPHPFGLTQY--QDYIYWTDWSRRS 854
Query: 181 PKIEWAN-MDGTERSVLLGSPDVKLPTL 261
IE AN G R+++ G D + L
Sbjct: 855 --IERANKTSGQNRTIIQGHLDYVMDIL 880
Score = 40.7 bits (91), Expect = 0.004
Identities = 25/79 (31%), Positives = 43/79 (54%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
I+WTD + I + +D + + + Q I++P GIAV ++WTD +IE
Sbjct: 374 IYWTDDEVRAIRRSFIDGSGSQFVVTAQ-IAHPDGIAVDWVARNLYWTD--TGTDRIEVT 430
Query: 199 NMDGTERSVLLGSPDVKLP 255
++GT R +L+ S D++ P
Sbjct: 431 RLNGTMRKILI-SEDLEEP 448
Score = 39.9 bits (89), Expect = 0.007
Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAINGDKLYWSDWRT 431
N + +D+ ++ +ADA L I +L + + + + +PF L + D LYW+DW T
Sbjct: 185 NGLTLDYEEQKLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTLFEDILYWTDWST 244
Query: 432 LKI 440
I
Sbjct: 245 HSI 247
Score = 39.1 bits (87), Expect = 0.013
Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D+ I+W D+K IEV N D R+VL I + G + ++WTDW R +
Sbjct: 498 DYDEGKIYWGDAKTDKIEVMNTDGTGRRVLVE-DKIPHIFGFTL--LGDYVYWTDWQRRS 554
Query: 181 PKIEWANMDGTERSVLLGS-PDV 246
IE + ER V++ PD+
Sbjct: 555 --IERVHKRSAEREVIIDQLPDL 575
Score = 38.3 bits (85), Expect = 0.022
Identities = 17/64 (26%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN-CRYPFGLAINGDKLYWSDWRT 431
N +A+D+ ++ + DA I+ ++ + E+ + FG + GD +YW+DW+
Sbjct: 493 NGLALDYDEGKIYWGDAKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTLLGDYVYWTDWQR 552
Query: 432 LKIE 443
IE
Sbjct: 553 RSIE 556
Score = 37.1 bits (82), Expect = 0.051
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +1
Query: 49 IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDGTERSVL 228
IE A LD R+VLF +S P +A+ + GK+FW D + +IE +++ G R VL
Sbjct: 1083 IERAALDGTEREVLF-FSGLSKPIALALDSRLGKLFWADSDLR--RIESSDLSGANRIVL 1139
Score = 35.9 bits (79), Expect = 0.12
Identities = 19/68 (27%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
Frame = +3
Query: 252 SNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAIN--GDKLYWSD 422
++++ D + +R+ + D L+ I ++ +E + E YP G+A++ G LYW+D
Sbjct: 664 ASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLYWAD 723
Query: 423 WRTLKIEI 446
T +IE+
Sbjct: 724 TGTNRIEV 731
Score = 35.1 bits (77), Expect = 0.21
Identities = 21/70 (30%), Positives = 37/70 (52%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
I+W+D + I+ + V + +P G+A K++WTD + +N +IE +
Sbjct: 65 IYWSDVSEEAIKRTEFNKTESVQNVVVSGLLSPDGLACDWLGEKLYWTD-SETN-RIEVS 122
Query: 199 NMDGTERSVL 228
N+DG+ R VL
Sbjct: 123 NLDGSLRKVL 132
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/57 (29%), Positives = 29/57 (50%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN 171
D+ + ++W D+K I +NLD R+ +V S P A+ ++WTDW+
Sbjct: 190 DYEEQKLYWADAKLNFIHKSNLDGTNRQ---AVVKGSLPHPFALTLFEDILYWTDWS 243
Score = 31.9 bits (69), Expect = 1.9
Identities = 15/41 (36%), Positives = 27/41 (65%), Gaps = 2/41 (4%)
Frame = +3
Query: 339 SRQIETIAENCRYPFGLAINGD--KLYWSDWRTLKIEIIDT 455
S ++ + + +P GLA++ D K+YW D +T KIE+++T
Sbjct: 479 SDRVVLVNTSLGWPNGLALDYDEGKIYWGDAKTDKIEVMNT 519
Score = 31.9 bits (69), Expect = 1.9
Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Frame = +3
Query: 258 SVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
++A+D ++ +AD+ L+ I+ DL + +I N P GL + + LYW D +
Sbjct: 1106 ALALDSRLGKLFWADSDLRRIESSDLSGANRIVLEDSNILQPVGLTVFENWLYWIDKQQQ 1165
Query: 435 KIEIID 452
IE ID
Sbjct: 1166 MIEKID 1171
Score = 29.9 bits (64), Expect = 7.7
Identities = 19/70 (27%), Positives = 36/70 (51%), Gaps = 6/70 (8%)
Frame = +3
Query: 255 NSVAIDW--SRDRVCFADAGLQVIKCIDLHSRQI--ETIAENCRYPFGLAIN--GDKLYW 416
++ A+D+ S + ++D + IK + + + + P GLA + G+KLYW
Sbjct: 52 DAAAVDFVFSHGLIYWSDVSEEAIKRTEFNKTESVQNVVVSGLLSPDGLACDWLGEKLYW 111
Query: 417 SDWRTLKIEI 446
+D T +IE+
Sbjct: 112 TDSETNRIEV 121
>BC117136-1|AAI17137.1| 1613|Homo sapiens low density lipoprotein
receptor-related protein 6 protein.
Length = 1613
Score = 82.6 bits (195), Expect = 1e-15
Identities = 38/79 (48%), Positives = 51/79 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++WTDS+ IEV+NLD +RKVLF Q + PR IA+ P G ++WTDW
Sbjct: 103 DWLGEKLYWTDSETNRIEVSNLDGSLRKVLF-WQELDQPRAIALDPSSGFMYWTDWGEV- 160
Query: 181 PKIEWANMDGTERSVLLGS 237
PKIE A MDG+ R +++ S
Sbjct: 161 PKIERAGMDGSSRFIIINS 179
Score = 76.2 bits (179), Expect = 9e-14
Identities = 35/79 (44%), Positives = 52/79 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ARN++WTD+ IEV L+ +RK+L S +++ PR I + P G ++WTDW
Sbjct: 411 DWVARNLYWTDTGTDRIEVTRLNGTMRKILIS-EDLEEPRAIVLDPMVGYMYWTDWGEI- 468
Query: 181 PKIEWANMDGTERSVLLGS 237
PKIE A +DG++R VL+ +
Sbjct: 469 PKIERAALDGSDRVVLVNT 487
Score = 69.7 bits (163), Expect = 8e-12
Identities = 31/77 (40%), Positives = 51/77 (66%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW +N++W D+ IEV+ LD + R+VL +++ +PR +A+ P G ++WT+W
Sbjct: 713 DWLGKNLYWADTGTNRIEVSKLDGQHRQVLV-WKDLDSPRALALDPAEGFMYWTEWG-GK 770
Query: 181 PKIEWANMDGTERSVLL 231
PKI+ A MDG+ER+ L+
Sbjct: 771 PKIDRAAMDGSERTTLV 787
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/79 (36%), Positives = 44/79 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +R I+WT I V LD + V+ + PR + V+P++G +++T+ +
Sbjct: 1022 DIYSRYIYWTCEATNVINVTRLDGRSVGVVLKGEQ-DRPRAVVVNPEKGYMYFTNLQERS 1080
Query: 181 PKIEWANMDGTERSVLLGS 237
PKIE A +DGTER VL S
Sbjct: 1081 PKIERAALDGTEREVLFFS 1099
Score = 47.6 bits (108), Expect = 4e-05
Identities = 21/69 (30%), Positives = 37/69 (53%)
Frame = +3
Query: 237 PRCEASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYW 416
P +N + ID+++ R+ + D +I+ ++ E IA++ +PFGL D +YW
Sbjct: 788 PNVGRANGLTIDYAKRRLYWTDLDTNLIESSNMLGLNREVIADDLPHPFGLTQYQDYIYW 847
Query: 417 SDWRTLKIE 443
+DW IE
Sbjct: 848 TDWSRRSIE 856
Score = 44.8 bits (101), Expect = 3e-04
Identities = 29/72 (40%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Frame = +1
Query: 19 IFWTDSKKLT-IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
++WTD ++ IE A LD R VL + ++ P G+A+ GKI+W D KIE
Sbjct: 460 MYWTDWGEIPKIERAALDGSDRVVLVNT-SLGWPNGLALDYDEGKIYWGD--AKTDKIEV 516
Query: 196 ANMDGTERSVLL 231
N DGT R VL+
Sbjct: 517 MNTDGTGRRVLV 528
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/88 (30%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D++ R ++WTD IE +N+ R+V+ ++ +P G+ + + I+WTDW+R +
Sbjct: 799 DYAKRRLYWTDLDTNLIESSNMLGLNREVI--ADDLPHPFGLTQY--QDYIYWTDWSRRS 854
Query: 181 PKIEWAN-MDGTERSVLLGSPDVKLPTL 261
IE AN G R+++ G D + L
Sbjct: 855 --IERANKTSGQNRTIIQGHLDYVMDIL 880
Score = 40.7 bits (91), Expect = 0.004
Identities = 25/79 (31%), Positives = 43/79 (54%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
I+WTD + I + +D + + + Q I++P GIAV ++WTD +IE
Sbjct: 374 IYWTDDEVRAIRRSFIDGSGSQFVVTAQ-IAHPDGIAVDWVARNLYWTD--TGTDRIEVT 430
Query: 199 NMDGTERSVLLGSPDVKLP 255
++GT R +L+ S D++ P
Sbjct: 431 RLNGTMRKILI-SEDLEEP 448
Score = 39.9 bits (89), Expect = 0.007
Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAINGDKLYWSDWRT 431
N + +D+ ++ +ADA L I +L + + + + +PF L + D LYW+DW T
Sbjct: 185 NGLTLDYEEQKLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTLFEDILYWTDWST 244
Query: 432 LKI 440
I
Sbjct: 245 HSI 247
Score = 39.1 bits (87), Expect = 0.013
Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D+ I+W D+K IEV N D R+VL I + G + ++WTDW R +
Sbjct: 498 DYDEGKIYWGDAKTDKIEVMNTDGTGRRVLVE-DKIPHIFGFTL--LGDYVYWTDWQRRS 554
Query: 181 PKIEWANMDGTERSVLLGS-PDV 246
IE + ER V++ PD+
Sbjct: 555 --IERVHKRSAEREVIIDQLPDL 575
Score = 38.3 bits (85), Expect = 0.022
Identities = 17/64 (26%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN-CRYPFGLAINGDKLYWSDWRT 431
N +A+D+ ++ + DA I+ ++ + E+ + FG + GD +YW+DW+
Sbjct: 493 NGLALDYDEGKIYWGDAKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTLLGDYVYWTDWQR 552
Query: 432 LKIE 443
IE
Sbjct: 553 RSIE 556
Score = 37.1 bits (82), Expect = 0.051
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +1
Query: 49 IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDGTERSVL 228
IE A LD R+VLF +S P +A+ + GK+FW D + +IE +++ G R VL
Sbjct: 1083 IERAALDGTEREVLF-FSGLSKPIALALDSRLGKLFWADSDLR--RIESSDLSGANRIVL 1139
Score = 35.9 bits (79), Expect = 0.12
Identities = 19/68 (27%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
Frame = +3
Query: 252 SNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAIN--GDKLYWSD 422
++++ D + +R+ + D L+ I ++ +E + E YP G+A++ G LYW+D
Sbjct: 664 ASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLYWAD 723
Query: 423 WRTLKIEI 446
T +IE+
Sbjct: 724 TGTNRIEV 731
Score = 35.1 bits (77), Expect = 0.21
Identities = 21/70 (30%), Positives = 37/70 (52%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
I+W+D + I+ + V + +P G+A K++WTD + +N +IE +
Sbjct: 65 IYWSDVSEEAIKRTEFNKTESVQNVVVSGLLSPDGLACDWLGEKLYWTD-SETN-RIEVS 122
Query: 199 NMDGTERSVL 228
N+DG+ R VL
Sbjct: 123 NLDGSLRKVL 132
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/57 (29%), Positives = 29/57 (50%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN 171
D+ + ++W D+K I +NLD R+ +V S P A+ ++WTDW+
Sbjct: 190 DYEEQKLYWADAKLNFIHKSNLDGTNRQ---AVVKGSLPHPFALTLFEDILYWTDWS 243
Score = 31.9 bits (69), Expect = 1.9
Identities = 15/41 (36%), Positives = 27/41 (65%), Gaps = 2/41 (4%)
Frame = +3
Query: 339 SRQIETIAENCRYPFGLAINGD--KLYWSDWRTLKIEIIDT 455
S ++ + + +P GLA++ D K+YW D +T KIE+++T
Sbjct: 479 SDRVVLVNTSLGWPNGLALDYDEGKIYWGDAKTDKIEVMNT 519
Score = 31.9 bits (69), Expect = 1.9
Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Frame = +3
Query: 258 SVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
++A+D ++ +AD+ L+ I+ DL + +I N P GL + + LYW D +
Sbjct: 1106 ALALDSRLGKLFWADSDLRRIESSDLSGANRIVLEDSNILQPVGLTVFENWLYWIDKQQQ 1165
Query: 435 KIEIID 452
IE ID
Sbjct: 1166 MIEKID 1171
Score = 29.9 bits (64), Expect = 7.7
Identities = 19/70 (27%), Positives = 36/70 (51%), Gaps = 6/70 (8%)
Frame = +3
Query: 255 NSVAIDW--SRDRVCFADAGLQVIKCIDLHSRQI--ETIAENCRYPFGLAIN--GDKLYW 416
++ A+D+ S + ++D + IK + + + + P GLA + G+KLYW
Sbjct: 52 DAAAVDFVFSHGLIYWSDVSEEAIKRTEFNKTESVQNVVVSGLLSPDGLACDWLGEKLYW 111
Query: 417 SDWRTLKIEI 446
+D T +IE+
Sbjct: 112 TDSETNRIEV 121
>AF074264-1|AAC33006.1| 1613|Homo sapiens LDL receptor-related
protein 6 protein.
Length = 1613
Score = 82.6 bits (195), Expect = 1e-15
Identities = 38/79 (48%), Positives = 51/79 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++WTDS+ IEV+NLD +RKVLF Q + PR IA+ P G ++WTDW
Sbjct: 103 DWLGEKLYWTDSETNRIEVSNLDGSLRKVLF-WQELDQPRAIALDPSSGFMYWTDWGEV- 160
Query: 181 PKIEWANMDGTERSVLLGS 237
PKIE A MDG+ R +++ S
Sbjct: 161 PKIERAGMDGSSRFIIINS 179
Score = 76.2 bits (179), Expect = 9e-14
Identities = 35/79 (44%), Positives = 52/79 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ARN++WTD+ IEV L+ +RK+L S +++ PR I + P G ++WTDW
Sbjct: 411 DWVARNLYWTDTGTDRIEVTRLNGTMRKILIS-EDLEEPRAIVLDPMVGYMYWTDWGEI- 468
Query: 181 PKIEWANMDGTERSVLLGS 237
PKIE A +DG++R VL+ +
Sbjct: 469 PKIERAALDGSDRVVLVNT 487
Score = 69.7 bits (163), Expect = 8e-12
Identities = 31/77 (40%), Positives = 51/77 (66%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW +N++W D+ IEV+ LD + R+VL +++ +PR +A+ P G ++WT+W
Sbjct: 713 DWLGKNLYWADTGTNRIEVSKLDGQHRQVLV-WKDLDSPRALALDPAEGFMYWTEWG-GK 770
Query: 181 PKIEWANMDGTERSVLL 231
PKI+ A MDG+ER+ L+
Sbjct: 771 PKIDRAAMDGSERTTLV 787
Score = 55.2 bits (127), Expect = 2e-07
Identities = 30/79 (37%), Positives = 44/79 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +R I+WT I V LD + V+ + PR I V+P++G +++T+ +
Sbjct: 1022 DIYSRYIYWTCEATNVINVTRLDGRSVGVVLKGEQ-DRPRAIVVNPEKGYMYFTNLQERS 1080
Query: 181 PKIEWANMDGTERSVLLGS 237
PKIE A +DGTER VL S
Sbjct: 1081 PKIERAALDGTEREVLFFS 1099
Score = 47.6 bits (108), Expect = 4e-05
Identities = 21/69 (30%), Positives = 37/69 (53%)
Frame = +3
Query: 237 PRCEASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYW 416
P +N + ID+++ R+ + D +I+ ++ E IA++ +PFGL D +YW
Sbjct: 788 PNVGRANGLTIDYAKRRLYWTDLDTNLIESSNMLGLNREVIADDLPHPFGLTQYQDYIYW 847
Query: 417 SDWRTLKIE 443
+DW IE
Sbjct: 848 TDWSRRSIE 856
Score = 44.8 bits (101), Expect = 3e-04
Identities = 29/72 (40%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Frame = +1
Query: 19 IFWTDSKKLT-IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
++WTD ++ IE A LD R VL + ++ P G+A+ GKI+W D KIE
Sbjct: 460 MYWTDWGEIPKIERAALDGSDRVVLVNT-SLGWPNGLALDYDEGKIYWGD--AKTDKIEV 516
Query: 196 ANMDGTERSVLL 231
N DGT R VL+
Sbjct: 517 MNTDGTGRRVLV 528
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/88 (30%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D++ R ++WTD IE +N+ R+V+ ++ +P G+ + + I+WTDW+R +
Sbjct: 799 DYAKRRLYWTDLDTNLIESSNMLGLNREVI--ADDLPHPFGLTQY--QDYIYWTDWSRRS 854
Query: 181 PKIEWAN-MDGTERSVLLGSPDVKLPTL 261
IE AN G R+++ G D + L
Sbjct: 855 --IERANKTSGQNRTIIQGHLDYVMDIL 880
Score = 40.7 bits (91), Expect = 0.004
Identities = 25/79 (31%), Positives = 43/79 (54%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
I+WTD + I + +D + + + Q I++P GIAV ++WTD +IE
Sbjct: 374 IYWTDDEVRAIRRSFIDGSGSQFVVTAQ-IAHPDGIAVDWVARNLYWTD--TGTDRIEVT 430
Query: 199 NMDGTERSVLLGSPDVKLP 255
++GT R +L+ S D++ P
Sbjct: 431 RLNGTMRKILI-SEDLEEP 448
Score = 39.9 bits (89), Expect = 0.007
Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAINGDKLYWSDWRT 431
N + +D+ ++ +ADA L I +L + + + + +PF L + D LYW+DW T
Sbjct: 185 NGLTLDYEEQKLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTLFEDILYWTDWST 244
Query: 432 LKI 440
I
Sbjct: 245 HSI 247
Score = 39.1 bits (87), Expect = 0.013
Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D+ I+W D+K IEV N D R+VL I + G + ++WTDW R +
Sbjct: 498 DYDEGKIYWGDAKTDKIEVMNTDGTGRRVLVE-DKIPHIFGFTL--LGDYVYWTDWQRRS 554
Query: 181 PKIEWANMDGTERSVLLGS-PDV 246
IE + ER V++ PD+
Sbjct: 555 --IERVHKRSAEREVIIDQLPDL 575
Score = 38.3 bits (85), Expect = 0.022
Identities = 17/64 (26%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN-CRYPFGLAINGDKLYWSDWRT 431
N +A+D+ ++ + DA I+ ++ + E+ + FG + GD +YW+DW+
Sbjct: 493 NGLALDYDEGKIYWGDAKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTLLGDYVYWTDWQR 552
Query: 432 LKIE 443
IE
Sbjct: 553 RSIE 556
Score = 37.1 bits (82), Expect = 0.051
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +1
Query: 49 IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDGTERSVL 228
IE A LD R+VLF +S P +A+ + GK+FW D + +IE +++ G R VL
Sbjct: 1083 IERAALDGTEREVLF-FSGLSKPIALALDSRLGKLFWADSDLR--RIESSDLSGANRIVL 1139
Score = 35.9 bits (79), Expect = 0.12
Identities = 19/68 (27%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
Frame = +3
Query: 252 SNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAIN--GDKLYWSD 422
++++ D + +R+ + D L+ I ++ +E + E YP G+A++ G LYW+D
Sbjct: 664 ASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLYWAD 723
Query: 423 WRTLKIEI 446
T +IE+
Sbjct: 724 TGTNRIEV 731
Score = 35.1 bits (77), Expect = 0.21
Identities = 21/70 (30%), Positives = 37/70 (52%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
I+W+D + I+ + V + +P G+A K++WTD + +N +IE +
Sbjct: 65 IYWSDVSEEAIKRTEFNKTESVQNVVVSGLLSPDGLACDWLGEKLYWTD-SETN-RIEVS 122
Query: 199 NMDGTERSVL 228
N+DG+ R VL
Sbjct: 123 NLDGSLRKVL 132
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/57 (29%), Positives = 29/57 (50%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN 171
D+ + ++W D+K I +NLD R+ +V S P A+ ++WTDW+
Sbjct: 190 DYEEQKLYWADAKLNFIHKSNLDGTNRQ---AVVKGSLPHPFALTLFEDILYWTDWS 243
Score = 31.9 bits (69), Expect = 1.9
Identities = 15/41 (36%), Positives = 27/41 (65%), Gaps = 2/41 (4%)
Frame = +3
Query: 339 SRQIETIAENCRYPFGLAINGD--KLYWSDWRTLKIEIIDT 455
S ++ + + +P GLA++ D K+YW D +T KIE+++T
Sbjct: 479 SDRVVLVNTSLGWPNGLALDYDEGKIYWGDAKTDKIEVMNT 519
Score = 31.9 bits (69), Expect = 1.9
Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Frame = +3
Query: 258 SVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
++A+D ++ +AD+ L+ I+ DL + +I N P GL + + LYW D +
Sbjct: 1106 ALALDSRLGKLFWADSDLRRIESSDLSGANRIVLEDSNILQPVGLTVFENWLYWIDKQQQ 1165
Query: 435 KIEIID 452
IE ID
Sbjct: 1166 MIEKID 1171
Score = 29.9 bits (64), Expect = 7.7
Identities = 19/70 (27%), Positives = 36/70 (51%), Gaps = 6/70 (8%)
Frame = +3
Query: 255 NSVAIDW--SRDRVCFADAGLQVIKCIDLHSRQI--ETIAENCRYPFGLAIN--GDKLYW 416
++ A+D+ S + ++D + IK + + + + P GLA + G+KLYW
Sbjct: 52 DAAAVDFVFSHGLIYWSDVSEEAIKRTEFNKTESVQNVVVSGLLSPDGLACDWLGEKLYW 111
Query: 417 SDWRTLKIEI 446
+D T +IE+
Sbjct: 112 TDSETNRIEV 121
>AB231861-1|BAE19679.1| 1950|Homo sapiens low-density lipoprotein
receptor-related protein 4 protein.
Length = 1950
Score = 81.8 bits (193), Expect = 2e-15
Identities = 38/76 (50%), Positives = 50/76 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++WTDS IEVANLD RKVL QN+ PR IA+HP G I+WTDW +
Sbjct: 567 DWVHDKLYWTDSGTSRIEVANLDGAHRKVLLW-QNLEKPRAIALHPMEGTIYWTDWG-NT 624
Query: 181 PKIEWANMDGTERSVL 228
P+IE ++MDG+ R ++
Sbjct: 625 PRIEASSMDGSGRRII 640
Score = 76.6 bits (180), Expect = 7e-14
Identities = 37/79 (46%), Positives = 52/79 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ARN++WTD+ + TIE + LD RKVL + ++ IA P++G +FWTDW
Sbjct: 1484 DWVARNLYWTDTGRNTIEASRLDGSCRKVLIN----NSLDDIAAFPRKGYLFWTDWGHI- 1538
Query: 181 PKIEWANMDGTERSVLLGS 237
KIE AN+DG+ER VL+ +
Sbjct: 1539 AKIERANLDGSERKVLINT 1557
Score = 74.9 bits (176), Expect = 2e-13
Identities = 36/79 (45%), Positives = 47/79 (59%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++WTD+ IEVAN D +R VL +N+ PR I V P G ++WTDW S
Sbjct: 872 DWVTNKLYWTDAGTDRIEVANTDGSMRTVLIW-ENLDRPRDIVVEPMGGYMYWTDWGAS- 929
Query: 181 PKIEWANMDGTERSVLLGS 237
PKIE A MD + R V++ S
Sbjct: 930 PKIERAGMDASGRQVIISS 948
Score = 73.3 bits (172), Expect = 6e-13
Identities = 34/79 (43%), Positives = 52/79 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D R ++WTD+ IEV NLD +RKVL QN+ +PR I ++ + G ++WTDW N
Sbjct: 1180 DAIGRKVYWTDTGTNRIEVGNLDGSMRKVLV-WQNLDSPRAIVLYHEMGFMYWTDWG-EN 1237
Query: 181 PKIEWANMDGTERSVLLGS 237
K+E + MDG++R+VL+ +
Sbjct: 1238 AKLERSGMDGSDRAVLINN 1256
Score = 59.3 bits (137), Expect = 1e-08
Identities = 26/70 (37%), Positives = 44/70 (62%), Gaps = 1/70 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAINGDKLYWSDWRT 431
N +AID+ R+ +ADAG++ I+ L S++ I +PFGL + G+++YW+DW+T
Sbjct: 954 NGLAIDYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQLPHPFGLTLYGERIYWTDWQT 1013
Query: 432 LKIEIIDTIT 461
I+ D +T
Sbjct: 1014 KSIQSADRLT 1023
Score = 49.6 bits (113), Expect = 9e-06
Identities = 27/79 (34%), Positives = 45/79 (56%), Gaps = 2/79 (2%)
Frame = +1
Query: 1 DWSARN--IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
DW +R+ ++WTD TI A D ++V+ ++ +P G+A+ K++WTD
Sbjct: 827 DWDSRDDHVYWTDVSTDTISRAKWDGTGQEVVVDT-SLESPAGLAIDWVTNKLYWTD--A 883
Query: 175 SNPKIEWANMDGTERSVLL 231
+IE AN DG+ R+VL+
Sbjct: 884 GTDRIEVANTDGSMRTVLI 902
Score = 48.8 bits (111), Expect = 2e-05
Identities = 27/77 (35%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D+ ++ ++W D+ TIE A LD RKVL Q + +P G+ ++ +R I+WTDW +
Sbjct: 959 DYGSQRLYWADAGMKTIEFAGLDGSKRKVLIGSQ-LPHPFGLTLYGER--IYWTDWQTKS 1015
Query: 181 PKIEWAN-MDGTERSVL 228
I+ A+ + G +R L
Sbjct: 1016 --IQSADRLTGLDRETL 1030
Score = 48.4 bits (110), Expect = 2e-05
Identities = 26/74 (35%), Positives = 43/74 (58%), Gaps = 1/74 (1%)
Frame = +1
Query: 19 IFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
++WTD IE A +D R+V+ S N++ P G+A+ +++W D IE+
Sbjct: 921 MYWTDWGASPKIERAGMDASGRQVIIS-SNLTWPNGLAIDYGSQRLYWADAGMKT--IEF 977
Query: 196 ANMDGTERSVLLGS 237
A +DG++R VL+GS
Sbjct: 978 AGLDGSKRKVLIGS 991
Score = 47.2 bits (107), Expect = 5e-05
Identities = 19/66 (28%), Positives = 36/66 (54%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
N + +D + ++ +ADA + I+ DL+ T+ ++P+GL + +YW+DW+T
Sbjct: 1262 NGLTVDKASSQLLWADAHTERIEAADLNGANRHTLVSPVQHPYGLTLLDSYIYWTDWQTR 1321
Query: 435 KIEIID 452
I D
Sbjct: 1322 SIHRAD 1327
Score = 46.8 bits (106), Expect = 6e-05
Identities = 19/66 (28%), Positives = 36/66 (54%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
N + +D+ R+ + DA L I+ DL+ + + + + +PF L +YW+DW+T
Sbjct: 1563 NGLTLDYDTRRIYWVDAHLDRIESADLNGKLRQVLVGHVSHPFALTQQDRWIYWTDWQTK 1622
Query: 435 KIEIID 452
I+ +D
Sbjct: 1623 SIQRVD 1628
Score = 46.4 bits (105), Expect = 8e-05
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN 171
D++ R ++W D+K IE ANLD RK + S Q + +P I V ++WTDW+
Sbjct: 654 DYAGRRMYWVDAKHHVIERANLDGSHRKAVIS-QGLPHPFAITVF--EDSLYWTDWH 707
Score = 44.4 bits (100), Expect = 3e-04
Identities = 28/72 (38%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLD-TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
+FW+D I ANL+ + V +V+ + + +P G+AV K++WTD S +IE
Sbjct: 530 VFWSDVTLDRILRANLNGSNVEEVVST--GLESPGGLAVDWVHDKLYWTDSGTS--RIEV 585
Query: 196 ANMDGTERSVLL 231
AN+DG R VLL
Sbjct: 586 ANLDGAHRKVLL 597
Score = 44.4 bits (100), Expect = 3e-04
Identities = 23/76 (30%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAINGDKLYWSDWRT 431
N + ID++ R+ + DA VI+ +L S + I++ +PF + + D LYW+DW T
Sbjct: 649 NGLTIDYAGRRMYWVDAKHHVIERANLDGSHRKAVISQGLPHPFAITVFEDSLYWTDWHT 708
Query: 432 LKIEIIDTITQARGQI 479
I + T +I
Sbjct: 709 KSINSANKFTGKNQEI 724
Score = 37.1 bits (82), Expect = 0.051
Identities = 23/69 (33%), Positives = 40/69 (57%), Gaps = 5/69 (7%)
Frame = +3
Query: 255 NSVAIDWS--RDRVCFADAGLQVIKCIDLHSRQIE-TIAENCRYPFGLAING--DKLYWS 419
N++A+D+ R+ V ++D L I +L+ +E ++ P GLA++ DKLYW+
Sbjct: 517 NAIALDFHHRRELVFWSDVTLDRILRANLNGSNVEEVVSTGLESPGGLAVDWVHDKLYWT 576
Query: 420 DWRTLKIEI 446
D T +IE+
Sbjct: 577 DSGTSRIEV 585
Score = 37.1 bits (82), Expect = 0.051
Identities = 26/78 (33%), Positives = 40/78 (51%), Gaps = 5/78 (6%)
Frame = +3
Query: 237 PRCEASNSVAIDW-SRD-RVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAING-- 401
P + ++VA+DW SRD V + D I E + + + P GLAI+
Sbjct: 816 PLADVRSAVALDWDSRDDHVYWTDVSTDTISRAKWDGTGQEVVVDTSLESPAGLAIDWVT 875
Query: 402 DKLYWSDWRTLKIEIIDT 455
+KLYW+D T +IE+ +T
Sbjct: 876 NKLYWTDAGTDRIEVANT 893
Score = 36.3 bits (80), Expect = 0.089
Identities = 19/70 (27%), Positives = 37/70 (52%), Gaps = 4/70 (5%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIA-ENCRYPFGLAIN--GDKLYW 416
E+ +A+DW D++ + D+G I+ +L + + +N P +A++ +YW
Sbjct: 559 ESPGGLAVDWVHDKLYWTDSGTSRIEVANLDGAHRKVLLWQNLEKPRAIALHPMEGTIYW 618
Query: 417 SDW-RTLKIE 443
+DW T +IE
Sbjct: 619 TDWGNTPRIE 628
Score = 34.3 bits (75), Expect = 0.36
Identities = 19/63 (30%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAIN--GDKLYW 416
E+ +AIDW +++ + DAG I+ + S + I EN P + + G +YW
Sbjct: 864 ESPAGLAIDWVTNKLYWTDAGTDRIEVANTDGSMRTVLIWENLDRPRDIVVEPMGGYMYW 923
Query: 417 SDW 425
+DW
Sbjct: 924 TDW 926
Score = 34.3 bits (75), Expect = 0.36
Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Frame = +1
Query: 16 NIFWTDSKKLTIEVANLDTKVRKVLFSVQNIS--NPRGIAVHPQRGKIFWTDWNRSNPKI 189
N F ++++ I + +LD + NI+ N + V PQ GK++W+D + +I
Sbjct: 1096 NSFLIFARRIDIRMVSLDIPYFADVVVPINITMKNTIAVGVDPQEGKVYWSD--STLHRI 1153
Query: 190 EWANMDGTERSVLL 231
AN+DG++ ++
Sbjct: 1154 SRANLDGSQHEDII 1167
Score = 31.5 bits (68), Expect = 2.5
Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 3/66 (4%)
Frame = +3
Query: 258 SVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAIN--GDKLYWSDWR 428
+V +D +V ++D+ L I +L Q E I + GLA++ G K+YW+D
Sbjct: 1133 AVGVDPQEGKVYWSDSTLHRISRANLDGSQHEDIITTGLQTTDGLAVDAIGRKVYWTDTG 1192
Query: 429 TLKIEI 446
T +IE+
Sbjct: 1193 TNRIEV 1198
>X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related precursor
(AA -19 to 4525) protein.
Length = 4544
Score = 80.6 bits (190), Expect = 4e-15
Identities = 38/77 (49%), Positives = 51/77 (66%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW A NI+WTD IEVA L+ R V+ S Q + PR I VHP++G +FWT+W +
Sbjct: 1973 DWIAGNIYWTDQGFDVIEVARLNGSFRYVVIS-QGLDKPRAITVHPEKGYLFWTEWGQ-Y 2030
Query: 181 PKIEWANMDGTERSVLL 231
P+IE + +DGTER VL+
Sbjct: 2031 PRIERSRLDGTERVVLV 2047
Score = 76.2 bits (179), Expect = 9e-14
Identities = 39/86 (45%), Positives = 53/86 (61%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW A N++WTDS + IEVA + + RK L S I P I V P RG ++W+DW ++
Sbjct: 3966 DWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGM-IDEPHAIVVDPLRGTMYWSDWG-NH 4023
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPT 258
PKIE A MDGT R L+ +++ PT
Sbjct: 4024 PKIETAAMDGTLRETLV-QDNIQWPT 4048
Score = 73.3 bits (172), Expect = 6e-13
Identities = 35/73 (47%), Positives = 47/73 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW A NI+W +S IEVA LD +R L + +I +PR IA+ P+ G +FWTDW+ S
Sbjct: 1352 DWIAGNIYWVESNLDQIEVAKLDGTLRTTLLA-GDIEHPRAIALDPRDGILFWTDWDASL 1410
Query: 181 PKIEWANMDGTER 219
P+IE A+M G R
Sbjct: 1411 PRIEAASMSGAGR 1423
Score = 70.9 bits (166), Expect = 3e-12
Identities = 35/78 (44%), Positives = 47/78 (60%), Gaps = 2/78 (2%)
Frame = +1
Query: 1 DWSARNIFWT--DSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
DW +RN+FWT D+ K I VA LD + + VQ + P G+ VHP RGK++WTD
Sbjct: 1666 DWVSRNLFWTSYDTNKKQINVARLDGSFKNAV--VQGLEQPHGLVVHPLRGKLYWTD--- 1720
Query: 175 SNPKIEWANMDGTERSVL 228
I ANMDG+ R++L
Sbjct: 1721 -GDNISMANMDGSNRTLL 1737
Score = 62.5 bits (145), Expect = 1e-09
Identities = 34/90 (37%), Positives = 49/90 (54%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW N++W D + TIEV+ L+ R VL S + PR + V Q G ++WTDW +
Sbjct: 3110 DWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVS-SGLREPRALVVDVQNGYLYWTDWG-DH 3167
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPTLWPS 270
I MDG+ RSV++ D K+ WP+
Sbjct: 3168 SLIGRIGMDGSSRSVIV---DTKI--TWPN 3192
Score = 60.1 bits (139), Expect = 6e-09
Identities = 36/98 (36%), Positives = 52/98 (53%), Gaps = 8/98 (8%)
Frame = +1
Query: 1 DWSARNIFWTDS-KKLTIEVANLD--TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN 171
DW N++WTD K TI VA L+ + RK L + +++PR I V P G ++WTDW
Sbjct: 610 DWMGDNLYWTDDGPKKTISVARLEKAAQTRKTLIEGK-MTHPRAIVVDPLNGWMYWTDWE 668
Query: 172 RS-----NPKIEWANMDGTERSVLLGSPDVKLPTLWPS 270
++E A MDG+ R + + S V LWP+
Sbjct: 669 EDPKDSRRGRLERAWMDGSHRDIFVTSKTV----LWPN 702
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/79 (35%), Positives = 44/79 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW N ++ D I V N + L ++ + NP+GIA+ P GK+F+TD+ +
Sbjct: 288 DWLTGNFYFVDDIDDRIFVCNRNGDTCVTLLDLE-LYNPKGIALDPAMGKVFFTDYGQI- 345
Query: 181 PKIEWANMDGTERSVLLGS 237
PK+E +MDG R+ L+ S
Sbjct: 346 PKVERCDMDGQNRTKLVDS 364
Score = 42.7 bits (96), Expect = 0.001
Identities = 30/80 (37%), Positives = 46/80 (57%), Gaps = 2/80 (2%)
Frame = +1
Query: 19 IFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
+FWT+ + IE + LD R VL +V +IS P GI+V Q GK++W D KIE
Sbjct: 2022 LFWTEWGQYPRIERSRLDGTERVVLVNV-SISWPNGISVDYQDGKLYWCD--ARTDKIER 2078
Query: 196 ANMD-GTERSVLLGSPDVKL 252
+++ G R V+L S ++ +
Sbjct: 2079 IDLETGENREVVLSSNNMDM 2098
Score = 42.7 bits (96), Expect = 0.001
Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVI-KCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDW 425
N +AID +++ F+DA L I +C S + + +PFGLA+ G+ ++W+DW
Sbjct: 2380 NGLAIDHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHPFGLAVYGEHIFWTDW 2437
Score = 38.3 bits (85), Expect = 0.022
Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 2/81 (2%)
Frame = +1
Query: 1 DWSARNIFWTD--SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
D+ + I+WTD ++ I +L+ +VL +SNP G+AV G ++W D R
Sbjct: 3065 DYREQMIYWTDVTTQGSMIRRMHLNGSNVQVLHRT-GLSNPDGLAVDWVGGNLYWCDKGR 3123
Query: 175 SNPKIEWANMDGTERSVLLGS 237
IE + ++G R+VL+ S
Sbjct: 3124 DT--IEVSKLNGAYRTVLVSS 3142
Score = 37.1 bits (82), Expect = 0.051
Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAINGDKLYWSDWRT 431
N + +D+ +R+ +ADA I+ L S + ++++ + F L + D +YW+DW T
Sbjct: 3192 NGLTLDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIPHIFALTLFEDYVYWTDWET 3251
Query: 432 LKI 440
I
Sbjct: 3252 KSI 3254
Score = 36.3 bits (80), Expect = 0.089
Identities = 20/84 (23%), Positives = 37/84 (44%), Gaps = 5/84 (5%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTK-----VRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNP 183
++WT TI +D R+ + ++ +PR + + +FWT+WN +P
Sbjct: 2297 LYWTSYTTSTITRHTVDQTRPGAFERETVITMSGDDHPRAFVLDECQNLMFWTNWNEQHP 2356
Query: 184 KIEWANMDGTERSVLLGSPDVKLP 255
I A + G L+ D++ P
Sbjct: 2357 SIMRAALSGANVLTLI-EKDIRTP 2379
Score = 35.9 bits (79), Expect = 0.12
Identities = 21/80 (26%), Positives = 45/80 (56%), Gaps = 3/80 (3%)
Frame = +1
Query: 1 DWSARN--IFWTDSKKLTIEVANLD-TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN 171
D+ AR ++W+D + I+ A ++ T V V+ + ++ N G+AV +FWT ++
Sbjct: 1621 DYDAREQRVYWSDVRTQAIKRAFINGTGVETVVSA--DLPNAHGLAVDWVSRNLFWTSYD 1678
Query: 172 RSNPKIEWANMDGTERSVLL 231
+ +I A +DG+ ++ ++
Sbjct: 1679 TNKKQINVARLDGSFKNAVV 1698
Score = 35.5 bits (78), Expect = 0.16
Identities = 17/72 (23%), Positives = 39/72 (54%)
Frame = +1
Query: 31 DSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDG 210
DS++ +E A +D R + + + + P G+++ G+++W D +IE ++G
Sbjct: 673 DSRRGRLERAWMDGSHRDIFVTSKTVLWPNGLSLDIPAGRLYWVD--AFYDRIETILLNG 730
Query: 211 TERSVLLGSPDV 246
T+R ++ P++
Sbjct: 731 TDRKIVYEGPEL 742
Score = 35.5 bits (78), Expect = 0.16
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSV---QNISNPRGIAVHPQRGKIFWTDWNRSNPKI 189
++WTD + I L F V ++ P G+AV G I+W + N +I
Sbjct: 1311 LYWTDVVEDKIYRGKLLDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLD--QI 1368
Query: 190 EWANMDGTERSVLLGSPDVKLP 255
E A +DGT R+ LL D++ P
Sbjct: 1369 EVAKLDGTLRTTLLAG-DIEHP 1389
Score = 35.5 bits (78), Expect = 0.16
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 3/62 (4%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIA--ENCRYPFGLAINGDKLYWSDW 425
N + +D+ R+ + DA I S +E + E +PF + + G ++YW+DW
Sbjct: 1437 NGLTVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDW 1496
Query: 426 RT 431
RT
Sbjct: 1497 RT 1498
Score = 35.5 bits (78), Expect = 0.16
Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 4/96 (4%)
Frame = +1
Query: 1 DWSARN--IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
D+ A N I+W D TI A D R+ + + I GIAV G I+WTD +
Sbjct: 1928 DFHAENDTIYWVDMGLSTISRAKRDQTWREDVVT-NGIGRVEGIAVDWIAGNIYWTD--Q 1984
Query: 175 SNPKIEWANMDGTERSVLL--GSPDVKLPTLWPSTG 276
IE A ++G+ R V++ G + T+ P G
Sbjct: 1985 GFDVIEVARLNGSFRYVVISQGLDKPRAITVHPEKG 2020
Score = 34.7 bits (76), Expect = 0.27
Identities = 17/46 (36%), Positives = 24/46 (52%)
Frame = +1
Query: 94 SVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDGTERSVLL 231
++ + PRGIA+ G ++WTD R IE A M G R L+
Sbjct: 3953 NISGLKMPRGIAIDWVAGNVYWTDSGRD--VIEVAQMKGENRKTLI 3996
Score = 33.5 bits (73), Expect = 0.63
Identities = 19/58 (32%), Positives = 31/58 (53%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
D A ++++D+ IE D R V+ + + +P G+AV+ + IFWTDW R
Sbjct: 2385 DHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPV-HPFGLAVYGEH--IFWTDWVR 2439
Score = 32.3 bits (70), Expect = 1.4
Identities = 18/61 (29%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVR-KVLFSVQNISNPRGIAVHPQRGKIFWTDWNRS 177
D+ + I W D++ I A D +VL + +S+P + ++ G+++WTDW R+
Sbjct: 1442 DYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYG--GEVYWTDW-RT 1498
Query: 178 N 180
N
Sbjct: 1499 N 1499
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIET-IAENCRYPFGLAIN--GDKLYWSDW 425
+AIDW V + D+G VI+ + +T I+ P + ++ +YWSDW
Sbjct: 3963 IAIDWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDW 4020
Score = 31.1 bits (67), Expect = 3.3
Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Frame = +1
Query: 19 IFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTD 165
++W+D IE A +D +R+ L NI P G+AV +++W D
Sbjct: 4015 MYWSDWGNHPKIETAAMDGTLRETLVQ-DNIQWPTGLAVDYHNERLYWAD 4063
Score = 30.3 bits (65), Expect = 5.8
Identities = 13/27 (48%), Positives = 16/27 (59%)
Frame = +2
Query: 548 NVCSQRNGNCNAGQLCLPNGSXGXSCL 628
N CS NG+C+ QLCLP SC+
Sbjct: 1848 NPCSVNNGDCS--QLCLPTSETTRSCM 1872
Score = 29.9 bits (64), Expect = 7.7
Identities = 16/61 (26%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN--CRYPFGLAINGDKLYWSDWR 428
N +++D R+ + DA I+ I L+ + + E + FGL +G+ L+W+++R
Sbjct: 702 NGLSLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWTEYR 761
Query: 429 T 431
+
Sbjct: 762 S 762
>DQ314873-1|ABC40732.1| 4544|Homo sapiens low density
lipoprotein-related protein 1 (alpha-2-macroglobulin
receptor) protein.
Length = 4544
Score = 80.6 bits (190), Expect = 4e-15
Identities = 38/77 (49%), Positives = 51/77 (66%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW A NI+WTD IEVA L+ R V+ S Q + PR I VHP++G +FWT+W +
Sbjct: 1973 DWIAGNIYWTDQGFDVIEVARLNGSFRYVVIS-QGLDKPRAITVHPEKGYLFWTEWGQ-Y 2030
Query: 181 PKIEWANMDGTERSVLL 231
P+IE + +DGTER VL+
Sbjct: 2031 PRIERSRLDGTERVVLV 2047
Score = 76.2 bits (179), Expect = 9e-14
Identities = 39/86 (45%), Positives = 53/86 (61%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW A N++WTDS + IEVA + + RK L S I P I V P RG ++W+DW ++
Sbjct: 3966 DWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGM-IDEPHAIVVDPLRGTMYWSDWG-NH 4023
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPT 258
PKIE A MDGT R L+ +++ PT
Sbjct: 4024 PKIETAAMDGTLRETLV-QDNIQWPT 4048
Score = 73.3 bits (172), Expect = 6e-13
Identities = 35/73 (47%), Positives = 47/73 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW A NI+W +S IEVA LD +R L + +I +PR IA+ P+ G +FWTDW+ S
Sbjct: 1352 DWIAGNIYWVESNLDQIEVAKLDGTLRTTLLA-GDIEHPRAIALDPRDGILFWTDWDASL 1410
Query: 181 PKIEWANMDGTER 219
P+IE A+M G R
Sbjct: 1411 PRIEAASMSGAGR 1423
Score = 70.9 bits (166), Expect = 3e-12
Identities = 35/78 (44%), Positives = 47/78 (60%), Gaps = 2/78 (2%)
Frame = +1
Query: 1 DWSARNIFWT--DSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
DW +RN+FWT D+ K I VA LD + + VQ + P G+ VHP RGK++WTD
Sbjct: 1666 DWVSRNLFWTSYDTNKKQINVARLDGSFKNAV--VQGLEQPHGLVVHPLRGKLYWTD--- 1720
Query: 175 SNPKIEWANMDGTERSVL 228
I ANMDG+ R++L
Sbjct: 1721 -GDNISMANMDGSNRTLL 1737
Score = 62.5 bits (145), Expect = 1e-09
Identities = 34/90 (37%), Positives = 49/90 (54%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW N++W D + TIEV+ L+ R VL S + PR + V Q G ++WTDW +
Sbjct: 3110 DWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVS-SGLREPRALVVDVQNGYLYWTDWG-DH 3167
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPTLWPS 270
I MDG+ RSV++ D K+ WP+
Sbjct: 3168 SLIGRIGMDGSSRSVIV---DTKI--TWPN 3192
Score = 60.1 bits (139), Expect = 6e-09
Identities = 36/98 (36%), Positives = 52/98 (53%), Gaps = 8/98 (8%)
Frame = +1
Query: 1 DWSARNIFWTDS-KKLTIEVANLD--TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN 171
DW N++WTD K TI VA L+ + RK L + +++PR I V P G ++WTDW
Sbjct: 610 DWMGDNLYWTDDGPKKTISVARLEKAAQTRKTLIEGK-MTHPRAIVVDPLNGWMYWTDWE 668
Query: 172 RS-----NPKIEWANMDGTERSVLLGSPDVKLPTLWPS 270
++E A MDG+ R + + S V LWP+
Sbjct: 669 EDPKDSRRGRLERAWMDGSHRDIFVTSKTV----LWPN 702
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/79 (35%), Positives = 44/79 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW N ++ D I V N + L ++ + NP+GIA+ P GK+F+TD+ +
Sbjct: 288 DWLTGNFYFVDDIDDRIFVCNRNGDTCVTLLDLE-LYNPKGIALDPAMGKVFFTDYGQI- 345
Query: 181 PKIEWANMDGTERSVLLGS 237
PK+E +MDG R+ L+ S
Sbjct: 346 PKVERCDMDGQNRTKLVDS 364
Score = 42.7 bits (96), Expect = 0.001
Identities = 30/80 (37%), Positives = 46/80 (57%), Gaps = 2/80 (2%)
Frame = +1
Query: 19 IFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
+FWT+ + IE + LD R VL +V +IS P GI+V Q GK++W D KIE
Sbjct: 2022 LFWTEWGQYPRIERSRLDGTERVVLVNV-SISWPNGISVDYQDGKLYWCD--ARTDKIER 2078
Query: 196 ANMD-GTERSVLLGSPDVKL 252
+++ G R V+L S ++ +
Sbjct: 2079 IDLETGENREVVLSSNNMDM 2098
Score = 42.7 bits (96), Expect = 0.001
Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVI-KCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDW 425
N +AID +++ F+DA L I +C S + + +PFGLA+ G+ ++W+DW
Sbjct: 2380 NGLAIDHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHPFGLAVYGEHIFWTDW 2437
Score = 38.3 bits (85), Expect = 0.022
Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 2/81 (2%)
Frame = +1
Query: 1 DWSARNIFWTD--SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
D+ + I+WTD ++ I +L+ +VL +SNP G+AV G ++W D R
Sbjct: 3065 DYREQMIYWTDVTTQGSMIRRMHLNGSNVQVLHRT-GLSNPDGLAVDWVGGNLYWCDKGR 3123
Query: 175 SNPKIEWANMDGTERSVLLGS 237
IE + ++G R+VL+ S
Sbjct: 3124 DT--IEVSKLNGAYRTVLVSS 3142
Score = 37.1 bits (82), Expect = 0.051
Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAINGDKLYWSDWRT 431
N + +D+ +R+ +ADA I+ L S + ++++ + F L + D +YW+DW T
Sbjct: 3192 NGLTLDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIPHIFALTLFEDYVYWTDWET 3251
Query: 432 LKI 440
I
Sbjct: 3252 KSI 3254
Score = 36.3 bits (80), Expect = 0.089
Identities = 20/84 (23%), Positives = 37/84 (44%), Gaps = 5/84 (5%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTK-----VRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNP 183
++WT TI +D R+ + ++ +PR + + +FWT+WN +P
Sbjct: 2297 LYWTSYTTSTITRHTVDQTRPGAFERETVITMSGDDHPRAFVLDECQNLMFWTNWNEQHP 2356
Query: 184 KIEWANMDGTERSVLLGSPDVKLP 255
I A + G L+ D++ P
Sbjct: 2357 SIMRAALSGANVLTLI-EKDIRTP 2379
Score = 35.9 bits (79), Expect = 0.12
Identities = 21/80 (26%), Positives = 45/80 (56%), Gaps = 3/80 (3%)
Frame = +1
Query: 1 DWSARN--IFWTDSKKLTIEVANLD-TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN 171
D+ AR ++W+D + I+ A ++ T V V+ + ++ N G+AV +FWT ++
Sbjct: 1621 DYDAREQRVYWSDVRTQAIKRAFINGTGVETVVSA--DLPNAHGLAVDWVSRNLFWTSYD 1678
Query: 172 RSNPKIEWANMDGTERSVLL 231
+ +I A +DG+ ++ ++
Sbjct: 1679 TNKKQINVARLDGSFKNAVV 1698
Score = 35.5 bits (78), Expect = 0.16
Identities = 17/72 (23%), Positives = 39/72 (54%)
Frame = +1
Query: 31 DSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDG 210
DS++ +E A +D R + + + + P G+++ G+++W D +IE ++G
Sbjct: 673 DSRRGRLERAWMDGSHRDIFVTSKTVLWPNGLSLDIPAGRLYWVD--AFYDRIETILLNG 730
Query: 211 TERSVLLGSPDV 246
T+R ++ P++
Sbjct: 731 TDRKIVYEGPEL 742
Score = 35.5 bits (78), Expect = 0.16
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSV---QNISNPRGIAVHPQRGKIFWTDWNRSNPKI 189
++WTD + I L F V ++ P G+AV G I+W + N +I
Sbjct: 1311 LYWTDVVEDKIYRGKLLDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLD--QI 1368
Query: 190 EWANMDGTERSVLLGSPDVKLP 255
E A +DGT R+ LL D++ P
Sbjct: 1369 EVAKLDGTLRTTLLAG-DIEHP 1389
Score = 35.5 bits (78), Expect = 0.16
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 3/62 (4%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIA--ENCRYPFGLAINGDKLYWSDW 425
N + +D+ R+ + DA I S +E + E +PF + + G ++YW+DW
Sbjct: 1437 NGLTVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDW 1496
Query: 426 RT 431
RT
Sbjct: 1497 RT 1498
Score = 35.5 bits (78), Expect = 0.16
Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 4/96 (4%)
Frame = +1
Query: 1 DWSARN--IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
D+ A N I+W D TI A D R+ + + I GIAV G I+WTD +
Sbjct: 1928 DFHAENDTIYWVDMGLSTISRAKRDQTWREDVVT-NGIGRVEGIAVDWIAGNIYWTD--Q 1984
Query: 175 SNPKIEWANMDGTERSVLL--GSPDVKLPTLWPSTG 276
IE A ++G+ R V++ G + T+ P G
Sbjct: 1985 GFDVIEVARLNGSFRYVVISQGLDKPRAITVHPEKG 2020
Score = 34.7 bits (76), Expect = 0.27
Identities = 17/46 (36%), Positives = 24/46 (52%)
Frame = +1
Query: 94 SVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDGTERSVLL 231
++ + PRGIA+ G ++WTD R IE A M G R L+
Sbjct: 3953 NISGLKMPRGIAIDWVAGNVYWTDSGRD--VIEVAQMKGENRKTLI 3996
Score = 33.5 bits (73), Expect = 0.63
Identities = 19/58 (32%), Positives = 31/58 (53%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
D A ++++D+ IE D R V+ + + +P G+AV+ + IFWTDW R
Sbjct: 2385 DHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPV-HPFGLAVYGEH--IFWTDWVR 2439
Score = 32.3 bits (70), Expect = 1.4
Identities = 18/61 (29%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVR-KVLFSVQNISNPRGIAVHPQRGKIFWTDWNRS 177
D+ + I W D++ I A D +VL + +S+P + ++ G+++WTDW R+
Sbjct: 1442 DYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYG--GEVYWTDW-RT 1498
Query: 178 N 180
N
Sbjct: 1499 N 1499
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIET-IAENCRYPFGLAIN--GDKLYWSDW 425
+AIDW V + D+G VI+ + +T I+ P + ++ +YWSDW
Sbjct: 3963 IAIDWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDW 4020
Score = 31.1 bits (67), Expect = 3.3
Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Frame = +1
Query: 19 IFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTD 165
++W+D IE A +D +R+ L NI P G+AV +++W D
Sbjct: 4015 MYWSDWGNHPKIETAAMDGTLRETLVQ-DNIQWPTGLAVDYHNERLYWAD 4063
Score = 30.3 bits (65), Expect = 5.8
Identities = 13/27 (48%), Positives = 16/27 (59%)
Frame = +2
Query: 548 NVCSQRNGNCNAGQLCLPNGSXGXSCL 628
N CS NG+C+ QLCLP SC+
Sbjct: 1848 NPCSVNNGDCS--QLCLPTSETTRSCM 1872
Score = 29.9 bits (64), Expect = 7.7
Identities = 16/61 (26%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN--CRYPFGLAINGDKLYWSDWR 428
N +++D R+ + DA I+ I L+ + + E + FGL +G+ L+W+++R
Sbjct: 702 NGLSLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWTEYR 761
Query: 429 T 431
+
Sbjct: 762 S 762
>AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-related
protein protein.
Length = 4544
Score = 80.6 bits (190), Expect = 4e-15
Identities = 38/77 (49%), Positives = 51/77 (66%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW A NI+WTD IEVA L+ R V+ S Q + PR I VHP++G +FWT+W +
Sbjct: 1973 DWIAGNIYWTDQGFDVIEVARLNGSFRYVVIS-QGLDKPRAITVHPEKGYLFWTEWGQ-Y 2030
Query: 181 PKIEWANMDGTERSVLL 231
P+IE + +DGTER VL+
Sbjct: 2031 PRIERSRLDGTERVVLV 2047
Score = 76.2 bits (179), Expect = 9e-14
Identities = 39/86 (45%), Positives = 53/86 (61%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW A N++WTDS + IEVA + + RK L S I P I V P RG ++W+DW ++
Sbjct: 3966 DWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGM-IDEPHAIVVDPLRGTMYWSDWG-NH 4023
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPT 258
PKIE A MDGT R L+ +++ PT
Sbjct: 4024 PKIETAAMDGTLRETLV-QDNIQWPT 4048
Score = 73.3 bits (172), Expect = 6e-13
Identities = 35/73 (47%), Positives = 47/73 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW A NI+W +S IEVA LD +R L + +I +PR IA+ P+ G +FWTDW+ S
Sbjct: 1352 DWIAGNIYWVESNLDQIEVAKLDGTLRTTLLA-GDIEHPRAIALDPRDGILFWTDWDASL 1410
Query: 181 PKIEWANMDGTER 219
P+IE A+M G R
Sbjct: 1411 PRIEAASMSGAGR 1423
Score = 70.9 bits (166), Expect = 3e-12
Identities = 35/78 (44%), Positives = 47/78 (60%), Gaps = 2/78 (2%)
Frame = +1
Query: 1 DWSARNIFWT--DSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
DW +RN+FWT D+ K I VA LD + + VQ + P G+ VHP RGK++WTD
Sbjct: 1666 DWVSRNLFWTSYDTNKKQINVARLDGSFKNAV--VQGLEQPHGLVVHPLRGKLYWTD--- 1720
Query: 175 SNPKIEWANMDGTERSVL 228
I ANMDG+ R++L
Sbjct: 1721 -GDNISMANMDGSNRTLL 1737
Score = 62.5 bits (145), Expect = 1e-09
Identities = 34/90 (37%), Positives = 49/90 (54%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW N++W D + TIEV+ L+ R VL S + PR + V Q G ++WTDW +
Sbjct: 3110 DWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVS-SGLREPRALVVDVQNGYLYWTDWG-DH 3167
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPTLWPS 270
I MDG+ RSV++ D K+ WP+
Sbjct: 3168 SLIGRIGMDGSSRSVIV---DTKI--TWPN 3192
Score = 60.1 bits (139), Expect = 6e-09
Identities = 36/98 (36%), Positives = 52/98 (53%), Gaps = 8/98 (8%)
Frame = +1
Query: 1 DWSARNIFWTDS-KKLTIEVANLD--TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN 171
DW N++WTD K TI VA L+ + RK L + +++PR I V P G ++WTDW
Sbjct: 610 DWMGDNLYWTDDGPKKTISVARLEKAAQTRKTLIEGK-MTHPRAIVVDPLNGWMYWTDWE 668
Query: 172 RS-----NPKIEWANMDGTERSVLLGSPDVKLPTLWPS 270
++E A MDG+ R + + S V LWP+
Sbjct: 669 EDPKDSRRGRLERAWMDGSHRDIFVTSKTV----LWPN 702
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/79 (35%), Positives = 44/79 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW N ++ D I V N + L ++ + NP+GIA+ P GK+F+TD+ +
Sbjct: 288 DWLTGNFYFVDDIDDRIFVCNRNGDTCVTLLDLE-LYNPKGIALDPAMGKVFFTDYGQI- 345
Query: 181 PKIEWANMDGTERSVLLGS 237
PK+E +MDG R+ L+ S
Sbjct: 346 PKVERCDMDGQNRTKLVDS 364
Score = 42.7 bits (96), Expect = 0.001
Identities = 30/80 (37%), Positives = 46/80 (57%), Gaps = 2/80 (2%)
Frame = +1
Query: 19 IFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
+FWT+ + IE + LD R VL +V +IS P GI+V Q GK++W D KIE
Sbjct: 2022 LFWTEWGQYPRIERSRLDGTERVVLVNV-SISWPNGISVDYQDGKLYWCD--ARTDKIER 2078
Query: 196 ANMD-GTERSVLLGSPDVKL 252
+++ G R V+L S ++ +
Sbjct: 2079 IDLETGENREVVLSSNNMDM 2098
Score = 42.7 bits (96), Expect = 0.001
Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVI-KCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDW 425
N +AID +++ F+DA L I +C S + + +PFGLA+ G+ ++W+DW
Sbjct: 2380 NGLAIDHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHPFGLAVYGEHIFWTDW 2437
Score = 38.3 bits (85), Expect = 0.022
Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 2/81 (2%)
Frame = +1
Query: 1 DWSARNIFWTD--SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
D+ + I+WTD ++ I +L+ +VL +SNP G+AV G ++W D R
Sbjct: 3065 DYREQMIYWTDVTTQGSMIRRMHLNGSNVQVLHRT-GLSNPDGLAVDWVGGNLYWCDKGR 3123
Query: 175 SNPKIEWANMDGTERSVLLGS 237
IE + ++G R+VL+ S
Sbjct: 3124 DT--IEVSKLNGAYRTVLVSS 3142
Score = 37.1 bits (82), Expect = 0.051
Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAINGDKLYWSDWRT 431
N + +D+ +R+ +ADA I+ L S + ++++ + F L + D +YW+DW T
Sbjct: 3192 NGLTLDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIPHIFALTLFEDYVYWTDWET 3251
Query: 432 LKI 440
I
Sbjct: 3252 KSI 3254
Score = 36.3 bits (80), Expect = 0.089
Identities = 20/84 (23%), Positives = 37/84 (44%), Gaps = 5/84 (5%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTK-----VRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNP 183
++WT TI +D R+ + ++ +PR + + +FWT+WN +P
Sbjct: 2297 LYWTSYTTSTITRHTVDQTRPGAFERETVITMSGDDHPRAFVLDECQNLMFWTNWNEQHP 2356
Query: 184 KIEWANMDGTERSVLLGSPDVKLP 255
I A + G L+ D++ P
Sbjct: 2357 SIMRAALSGANVLTLI-EKDIRTP 2379
Score = 35.9 bits (79), Expect = 0.12
Identities = 21/80 (26%), Positives = 45/80 (56%), Gaps = 3/80 (3%)
Frame = +1
Query: 1 DWSARN--IFWTDSKKLTIEVANLD-TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN 171
D+ AR ++W+D + I+ A ++ T V V+ + ++ N G+AV +FWT ++
Sbjct: 1621 DYDAREQRVYWSDVRTQAIKRAFINGTGVETVVSA--DLPNAHGLAVDWVSRNLFWTSYD 1678
Query: 172 RSNPKIEWANMDGTERSVLL 231
+ +I A +DG+ ++ ++
Sbjct: 1679 TNKKQINVARLDGSFKNAVV 1698
Score = 35.5 bits (78), Expect = 0.16
Identities = 17/72 (23%), Positives = 39/72 (54%)
Frame = +1
Query: 31 DSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDG 210
DS++ +E A +D R + + + + P G+++ G+++W D +IE ++G
Sbjct: 673 DSRRGRLERAWMDGSHRDIFVTSKTVLWPNGLSLDIPAGRLYWVD--AFYDRIETILLNG 730
Query: 211 TERSVLLGSPDV 246
T+R ++ P++
Sbjct: 731 TDRKIVYEGPEL 742
Score = 35.5 bits (78), Expect = 0.16
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSV---QNISNPRGIAVHPQRGKIFWTDWNRSNPKI 189
++WTD + I L F V ++ P G+AV G I+W + N +I
Sbjct: 1311 LYWTDVVEDKIYRGKLLDNGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLD--QI 1368
Query: 190 EWANMDGTERSVLLGSPDVKLP 255
E A +DGT R+ LL D++ P
Sbjct: 1369 EVAKLDGTLRTTLLAG-DIEHP 1389
Score = 35.5 bits (78), Expect = 0.16
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 3/62 (4%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIA--ENCRYPFGLAINGDKLYWSDW 425
N + +D+ R+ + DA I S +E + E +PF + + G ++YW+DW
Sbjct: 1437 NGLTVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDW 1496
Query: 426 RT 431
RT
Sbjct: 1497 RT 1498
Score = 35.5 bits (78), Expect = 0.16
Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 4/96 (4%)
Frame = +1
Query: 1 DWSARN--IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
D+ A N I+W D TI A D R+ + + I GIAV G I+WTD +
Sbjct: 1928 DFHAENDTIYWVDMGLSTISRAKRDQTWREDVVT-NGIGRVEGIAVDWIAGNIYWTD--Q 1984
Query: 175 SNPKIEWANMDGTERSVLL--GSPDVKLPTLWPSTG 276
IE A ++G+ R V++ G + T+ P G
Sbjct: 1985 GFDVIEVARLNGSFRYVVISQGLDKPRAITVHPEKG 2020
Score = 34.7 bits (76), Expect = 0.27
Identities = 17/46 (36%), Positives = 24/46 (52%)
Frame = +1
Query: 94 SVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDGTERSVLL 231
++ + PRGIA+ G ++WTD R IE A M G R L+
Sbjct: 3953 NISGLKMPRGIAIDWVAGNVYWTDSGRD--VIEVAQMKGENRKTLI 3996
Score = 33.5 bits (73), Expect = 0.63
Identities = 19/58 (32%), Positives = 31/58 (53%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
D A ++++D+ IE D R V+ + + +P G+AV+ + IFWTDW R
Sbjct: 2385 DHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPV-HPFGLAVYGEH--IFWTDWVR 2439
Score = 32.3 bits (70), Expect = 1.4
Identities = 18/61 (29%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVR-KVLFSVQNISNPRGIAVHPQRGKIFWTDWNRS 177
D+ + I W D++ I A D +VL + +S+P + ++ G+++WTDW R+
Sbjct: 1442 DYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYG--GEVYWTDW-RT 1498
Query: 178 N 180
N
Sbjct: 1499 N 1499
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIET-IAENCRYPFGLAIN--GDKLYWSDW 425
+AIDW V + D+G VI+ + +T I+ P + ++ +YWSDW
Sbjct: 3963 IAIDWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDW 4020
Score = 31.1 bits (67), Expect = 3.3
Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Frame = +1
Query: 19 IFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTD 165
++W+D IE A +D +R+ L NI P G+AV +++W D
Sbjct: 4015 MYWSDWGNHPKIETAAMDGTLRETLVQ-DNIQWPTGLAVDYHNERLYWAD 4063
Score = 30.3 bits (65), Expect = 5.8
Identities = 13/27 (48%), Positives = 16/27 (59%)
Frame = +2
Query: 548 NVCSQRNGNCNAGQLCLPNGSXGXSCL 628
N CS NG+C+ QLCLP SC+
Sbjct: 1848 NPCSVNNGDCS--QLCLPTSETTRSCM 1872
Score = 29.9 bits (64), Expect = 7.7
Identities = 16/61 (26%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN--CRYPFGLAINGDKLYWSDWR 428
N +++D R+ + DA I+ I L+ + + E + FGL +G+ L+W+++R
Sbjct: 702 NGLSLDIPAGRLYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWTEYR 761
Query: 429 T 431
+
Sbjct: 762 S 762
>U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein.
Length = 4655
Score = 78.6 bits (185), Expect = 2e-14
Identities = 40/86 (46%), Positives = 56/86 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW R+I+W+D K IEVA LD + RK L S ++ P IAV+P+ G +FWTDW +
Sbjct: 4150 DWVGRHIYWSDVKNKRIEVAKLDGRYRKWLIST-DLDQPAAIAVNPKLGLMFWTDWGK-E 4207
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPT 258
PKIE A M+G +R++L+ D+ PT
Sbjct: 4208 PKIESAWMNGEDRNILV-FEDLGWPT 4232
Score = 77.8 bits (183), Expect = 3e-14
Identities = 36/79 (45%), Positives = 56/79 (70%), Gaps = 2/79 (2%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGK--IFWTDWNR 174
DW RN++WTD TIEV+ +D R VL S +N++NPRG+A+ P+ + +FW+DW
Sbjct: 1517 DWVGRNLYWTDYALETIEVSKIDGSHRTVLIS-KNLTNPRGLALDPRMNEHLLFWSDWGH 1575
Query: 175 SNPKIEWANMDGTERSVLL 231
+P+IE A+MDG+ R+V++
Sbjct: 1576 -HPRIERASMDGSMRTVIV 1593
Score = 62.5 bits (145), Expect = 1e-09
Identities = 31/71 (43%), Positives = 44/71 (61%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++N++WTDS +I V L K R+ + VQ ++NPR + VHP G +F+TDW R
Sbjct: 792 DWISKNLYWTDSHYKSISVMRLADKTRRTV--VQYLNNPRSVVVHPFAGYLFFTDWFRP- 848
Query: 181 PKIEWANMDGT 213
KI A DG+
Sbjct: 849 AKIMRAWSDGS 859
Score = 60.5 bits (140), Expect = 5e-09
Identities = 35/92 (38%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN--R 174
DW I+ ++K I++ NLD R L + +N+ +PRGIAV P G +F++DW
Sbjct: 475 DWVNNKIYLVETKVNRIDMVNLDGSYRVTLIT-ENLGHPRGIAVDPTVGYLFFSDWESLS 533
Query: 175 SNPKIEWANMDGTERSVLLGSPDVKLPTLWPS 270
PK+E A MDG+ R L VK WP+
Sbjct: 534 GEPKLERAFMDGSNRKDL-----VKTKLGWPA 560
Score = 57.6 bits (133), Expect = 3e-08
Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 7/86 (8%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVL----FSVQN---ISNPRGIAVHPQRGKIFW 159
DW +R ++W D++ + V++L+ R++L N NPRG+A+HPQ G ++W
Sbjct: 3278 DWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYW 3337
Query: 160 TDWNRSNPKIEWANMDGTERSVLLGS 237
DW I MDGT +SV++ +
Sbjct: 3338 ADWGH-RAYIGRVGMDGTNKSVIIST 3362
Score = 52.8 bits (121), Expect = 1e-06
Identities = 32/85 (37%), Positives = 45/85 (52%), Gaps = 9/85 (10%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANL--DTKVRKVLFS----VQNISNPRGIAVHPQRGKIFWT 162
DW +RN++ T+ + +IEV L D + RK L + + P GI V P RGK++W+
Sbjct: 1829 DWISRNLYSTNPRTQSIEVLTLHGDIRYRKTLIANDGTALGVGFPIGITVDPARGKLYWS 1888
Query: 163 DWNRSN---PKIEWANMDGTERSVL 228
D + KI ANMDGT L
Sbjct: 1889 DQGTDSGVPAKIASANMDGTSVKTL 1913
Score = 49.6 bits (113), Expect = 9e-06
Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +3
Query: 240 RCEASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCR-YPFGLAINGDKLYW 416
+ E N + ID++ D + +ADA L I+ DL T+ + +PF + I D +YW
Sbjct: 3363 KLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDGALPHPFAITIFEDTIYW 3422
Query: 417 SDWRTLKIE 443
+DW T +E
Sbjct: 3423 TDWNTRTVE 3431
Score = 44.0 bits (99), Expect = 4e-04
Identities = 24/79 (30%), Positives = 39/79 (49%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW R I+++D I D R V + + PR I + P +G ++W DW+ ++
Sbjct: 2474 DWITRRIYYSDYLNQMINSMAEDGSNRTV---IARVPKPRAIVLDPCQGYLYWADWD-TH 2529
Query: 181 PKIEWANMDGTERSVLLGS 237
KIE A + G R ++ S
Sbjct: 2530 AKIERATLGGNFRVPIVNS 2548
Score = 43.6 bits (98), Expect = 6e-04
Identities = 25/61 (40%), Positives = 37/61 (60%), Gaps = 3/61 (4%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIK--CID-LHSRQIETIAENCRYPFGLAINGDKLYWSDW 425
N +AIDW+ R+ + DA I+ D L R++ I E +PFGLAI G+ L+++DW
Sbjct: 873 NGLAIDWAASRLYWVDAYFDKIEHSTFDGLDRRRLGHI-EQMTHPFGLAIFGEHLFFTDW 931
Query: 426 R 428
R
Sbjct: 932 R 932
Score = 42.7 bits (96), Expect = 0.001
Identities = 23/76 (30%), Positives = 41/76 (53%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW+A ++W D+ IE + D R+ L ++ +++P G+A+ + +F+TDW R
Sbjct: 878 DWAASRLYWVDAYFDKIEHSTFDGLDRRRLGHIEQMTHPFGLAIFGEH--LFFTDW-RLG 934
Query: 181 PKIEWANMDGTERSVL 228
I DG E +V+
Sbjct: 935 AIIRVRKADGGEMTVI 950
Score = 37.9 bits (84), Expect = 0.029
Identities = 19/62 (30%), Positives = 31/62 (50%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
+ + +D+ D + + DA LQ I+ L E I + FGL + G +YW+D T
Sbjct: 2554 SGLTLDYEEDLLYWVDASLQRIERSTLTGVDREVIVNAAVHAFGLTLYGQYIYWTDLYTQ 2613
Query: 435 KI 440
+I
Sbjct: 2614 RI 2615
Score = 37.5 bits (83), Expect = 0.038
Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Frame = +1
Query: 13 RNIFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTD 165
R +FW D ++ IE + LD R VL S + I PRG+AV G ++W D
Sbjct: 2202 RYLFWADYGQRPKIERSFLDCTNRTVLVS-EGIVTPRGLAVDRSDGYVYWVD 2252
Score = 35.1 bits (77), Expect = 0.21
Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 5/63 (7%)
Frame = +3
Query: 252 SNSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAI----NGDKLYW 416
+ ++AIDW + + D L+ I+ + S + I++N P GLA+ N L+W
Sbjct: 1511 TETIAIDWVGRNLYWTDYALETIEVSKIDGSHRTVLISKNLTNPRGLALDPRMNEHLLFW 1570
Query: 417 SDW 425
SDW
Sbjct: 1571 SDW 1573
Score = 34.7 bits (76), Expect = 0.27
Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRK-VLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
D ++ ++W DS+ IE D RK V+ I +P G+++ G++F+TDW +
Sbjct: 565 DMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLF--EGQVFFTDWTK 621
Score = 33.9 bits (74), Expect = 0.47
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 11/73 (15%)
Frame = +3
Query: 240 RCEASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENC---------RYPFGLA 392
R A+ S+A+DW ++ + DA L + DL+ +A++C P GLA
Sbjct: 3268 RLPAAESLAVDWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLA 3327
Query: 393 INGD--KLYWSDW 425
++ LYW+DW
Sbjct: 3328 LHPQYGYLYWADW 3340
Score = 32.3 bits (70), Expect = 1.4
Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D++ ++W D+ IE ++L+ R ++ + +P I + I+WTDWN
Sbjct: 3373 DYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDGA-LPHPFAITIFEDT--IYWTDWNTRT 3429
Query: 181 PKIEWAN-MDGTERSVLLGS 237
+E N DG+ R L+ +
Sbjct: 3430 --VEKGNKYDGSNRQTLVNT 3447
Score = 31.1 bits (67), Expect = 3.3
Identities = 19/61 (31%), Positives = 32/61 (52%)
Frame = +1
Query: 49 IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDGTERSVL 228
I AN+D K LF+ N+ + + + + K++W R IE N+DGT+R +L
Sbjct: 1900 IASANMDGTSVKTLFT-GNLEHLECVTLDIEEQKLYWAVTGRG--VIERGNVDGTDRMIL 1956
Query: 229 L 231
+
Sbjct: 1957 V 1957
Score = 31.1 bits (67), Expect = 3.3
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRY--PFGLAINGDKLYWSDWRTL 434
+A+D S V + D L +I I ++ E I RY P+G+ + + + W D R L
Sbjct: 2239 LAVDRSDGYVYWVDDSLDIIARIRINGENSEVIRYGSRYPTPYGITVFENSIIWVD-RNL 2297
Query: 435 K 437
K
Sbjct: 2298 K 2298
Score = 31.1 bits (67), Expect = 3.3
Identities = 21/60 (35%), Positives = 32/60 (53%)
Frame = +1
Query: 76 VRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDGTERSVLLGSPDVKLP 255
V++V ++ + P GIAV I+W+D N +IE A +DG R L+ S D+ P
Sbjct: 4131 VQEVDLKLKYVMQPDGIAVDWVGRHIYWSD--VKNKRIEVAKLDGRYRKWLI-STDLDQP 4187
Score = 30.7 bits (66), Expect = 4.4
Identities = 17/63 (26%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDL---HSRQIETIAENCRYPFGLAINGDKLYWSDWRT 431
+ ID+ + F D+ L + D H RQ+ R+P+ L + D +YW+D T
Sbjct: 1603 LTIDYPNRLLYFMDSYLDYMDFCDYNGHHRRQVIASDLIIRHPYALTLFEDSVYWTDRAT 1662
Query: 432 LKI 440
++
Sbjct: 1663 RRV 1665
Score = 30.7 bits (66), Expect = 4.4
Identities = 18/55 (32%), Positives = 30/55 (54%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTD 165
D + ++W + + IE N+D R +L V +S+P GIAVH +++TD
Sbjct: 1927 DIEEQKLYWAVTGRGVIERGNVDGTDRMIL--VHQLSHPWGIAVHD--SFLYYTD 1977
Score = 29.9 bits (64), Expect = 7.7
Identities = 15/76 (19%), Positives = 36/76 (47%), Gaps = 3/76 (3%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN---CRYPFGLAINGDKLYWSDWRT 431
V +D RV + D+ I+ + Q +T+ +PFG+++ +++++DW
Sbjct: 562 VTLDMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTK 621
Query: 432 LKIEIIDTITQARGQI 479
+ + + T+ Q+
Sbjct: 622 MAVLKANKFTETNPQV 637
>S73145-1|AAB30825.1| 268|Homo sapiens calcium sensor protein
protein.
Length = 268
Score = 78.6 bits (185), Expect = 2e-14
Identities = 40/86 (46%), Positives = 56/86 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW R+I+W+D K IEVA LD + RK L S ++ P IAV+P+ G +FWTDW +
Sbjct: 12 DWVGRHIYWSDVKNKRIEVAKLDGRYRKWLIST-DLDQPAAIAVNPKLGLMFWTDWGK-E 69
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPT 258
PKIE A M+G +R++L+ D+ PT
Sbjct: 70 PKIESAWMNGEDRNILV-FEDLGWPT 94
>AC007556-2|AAX88965.1| 3881|Homo sapiens unknown protein.
Length = 3881
Score = 78.6 bits (185), Expect = 2e-14
Identities = 40/86 (46%), Positives = 56/86 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW R+I+W+D K IEVA LD + RK L S ++ P IAV+P+ G +FWTDW +
Sbjct: 3376 DWVGRHIYWSDVKNKRIEVAKLDGRYRKWLIST-DLDQPAAIAVNPKLGLMFWTDWGK-E 3433
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPT 258
PKIE A M+G +R++L+ D+ PT
Sbjct: 3434 PKIESAWMNGEDRNILV-FEDLGWPT 3458
Score = 77.8 bits (183), Expect = 3e-14
Identities = 36/79 (45%), Positives = 56/79 (70%), Gaps = 2/79 (2%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGK--IFWTDWNR 174
DW RN++WTD TIEV+ +D R VL S +N++NPRG+A+ P+ + +FW+DW
Sbjct: 743 DWVGRNLYWTDYALETIEVSKIDGSHRTVLIS-KNLTNPRGLALDPRMNEHLLFWSDWGH 801
Query: 175 SNPKIEWANMDGTERSVLL 231
+P+IE A+MDG+ R+V++
Sbjct: 802 -HPRIERASMDGSMRTVIV 819
Score = 62.5 bits (145), Expect = 1e-09
Identities = 31/71 (43%), Positives = 44/71 (61%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++N++WTDS +I V L K R+ + VQ ++NPR + VHP G +F+TDW R
Sbjct: 18 DWISKNLYWTDSHYKSISVMRLADKTRRTV--VQYLNNPRSVVVHPFAGYLFFTDWFRP- 74
Query: 181 PKIEWANMDGT 213
KI A DG+
Sbjct: 75 AKIMRAWSDGS 85
Score = 57.6 bits (133), Expect = 3e-08
Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 7/86 (8%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVL----FSVQN---ISNPRGIAVHPQRGKIFW 159
DW +R ++W D++ + V++L+ R++L N NPRG+A+HPQ G ++W
Sbjct: 2504 DWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYW 2563
Query: 160 TDWNRSNPKIEWANMDGTERSVLLGS 237
DW I MDGT +SV++ +
Sbjct: 2564 ADWGH-RAYIGRVGMDGTNKSVIIST 2588
Score = 52.8 bits (121), Expect = 1e-06
Identities = 32/85 (37%), Positives = 45/85 (52%), Gaps = 9/85 (10%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANL--DTKVRKVLFS----VQNISNPRGIAVHPQRGKIFWT 162
DW +RN++ T+ + +IEV L D + RK L + + P GI V P RGK++W+
Sbjct: 1055 DWISRNLYSTNPRTQSIEVLTLHGDIRYRKTLIANDGTALGVGFPIGITVDPARGKLYWS 1114
Query: 163 DWNRSN---PKIEWANMDGTERSVL 228
D + KI ANMDGT L
Sbjct: 1115 DQGTDSGVPAKIASANMDGTSVKTL 1139
Score = 49.6 bits (113), Expect = 9e-06
Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +3
Query: 240 RCEASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCR-YPFGLAINGDKLYW 416
+ E N + ID++ D + +ADA L I+ DL T+ + +PF + I D +YW
Sbjct: 2589 KLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDGALPHPFAITIFEDTIYW 2648
Query: 417 SDWRTLKIE 443
+DW T +E
Sbjct: 2649 TDWNTRTVE 2657
Score = 44.0 bits (99), Expect = 4e-04
Identities = 24/79 (30%), Positives = 39/79 (49%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW R I+++D I D R V + + PR I + P +G ++W DW+ ++
Sbjct: 1700 DWITRRIYYSDYLNQMINSMAEDGSNRTV---IARVPKPRAIVLDPCQGYLYWADWD-TH 1755
Query: 181 PKIEWANMDGTERSVLLGS 237
KIE A + G R ++ S
Sbjct: 1756 AKIERATLGGNFRVPIVNS 1774
Score = 43.6 bits (98), Expect = 6e-04
Identities = 25/61 (40%), Positives = 37/61 (60%), Gaps = 3/61 (4%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIK--CID-LHSRQIETIAENCRYPFGLAINGDKLYWSDW 425
N +AIDW+ R+ + DA I+ D L R++ I E +PFGLAI G+ L+++DW
Sbjct: 99 NGLAIDWAASRLYWVDAYFDKIEHSTFDGLDRRRLGHI-EQMTHPFGLAIFGEHLFFTDW 157
Query: 426 R 428
R
Sbjct: 158 R 158
Score = 42.7 bits (96), Expect = 0.001
Identities = 23/76 (30%), Positives = 41/76 (53%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW+A ++W D+ IE + D R+ L ++ +++P G+A+ + +F+TDW R
Sbjct: 104 DWAASRLYWVDAYFDKIEHSTFDGLDRRRLGHIEQMTHPFGLAIFGEH--LFFTDW-RLG 160
Query: 181 PKIEWANMDGTERSVL 228
I DG E +V+
Sbjct: 161 AIIRVRKADGGEMTVI 176
Score = 37.9 bits (84), Expect = 0.029
Identities = 19/62 (30%), Positives = 31/62 (50%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
+ + +D+ D + + DA LQ I+ L E I + FGL + G +YW+D T
Sbjct: 1780 SGLTLDYEEDLLYWVDASLQRIERSTLTGVDREVIVNAAVHAFGLTLYGQYIYWTDLYTQ 1839
Query: 435 KI 440
+I
Sbjct: 1840 RI 1841
Score = 37.5 bits (83), Expect = 0.038
Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Frame = +1
Query: 13 RNIFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTD 165
R +FW D ++ IE + LD R VL S + I PRG+AV G ++W D
Sbjct: 1428 RYLFWADYGQRPKIERSFLDCTNRTVLVS-EGIVTPRGLAVDRSDGYVYWVD 1478
Score = 35.1 bits (77), Expect = 0.21
Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 5/63 (7%)
Frame = +3
Query: 252 SNSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAI----NGDKLYW 416
+ ++AIDW + + D L+ I+ + S + I++N P GLA+ N L+W
Sbjct: 737 TETIAIDWVGRNLYWTDYALETIEVSKIDGSHRTVLISKNLTNPRGLALDPRMNEHLLFW 796
Query: 417 SDW 425
SDW
Sbjct: 797 SDW 799
Score = 33.9 bits (74), Expect = 0.47
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 11/73 (15%)
Frame = +3
Query: 240 RCEASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENC---------RYPFGLA 392
R A+ S+A+DW ++ + DA L + DL+ +A++C P GLA
Sbjct: 2494 RLPAAESLAVDWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLA 2553
Query: 393 INGD--KLYWSDW 425
++ LYW+DW
Sbjct: 2554 LHPQYGYLYWADW 2566
Score = 32.3 bits (70), Expect = 1.4
Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D++ ++W D+ IE ++L+ R ++ + +P I + I+WTDWN
Sbjct: 2599 DYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDGA-LPHPFAITIFEDT--IYWTDWNTRT 2655
Query: 181 PKIEWAN-MDGTERSVLLGS 237
+E N DG+ R L+ +
Sbjct: 2656 --VEKGNKYDGSNRQTLVNT 2673
Score = 31.1 bits (67), Expect = 3.3
Identities = 19/61 (31%), Positives = 32/61 (52%)
Frame = +1
Query: 49 IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDGTERSVL 228
I AN+D K LF+ N+ + + + + K++W R IE N+DGT+R +L
Sbjct: 1126 IASANMDGTSVKTLFT-GNLEHLECVTLDIEEQKLYWAVTGRG--VIERGNVDGTDRMIL 1182
Query: 229 L 231
+
Sbjct: 1183 V 1183
Score = 31.1 bits (67), Expect = 3.3
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRY--PFGLAINGDKLYWSDWRTL 434
+A+D S V + D L +I I ++ E I RY P+G+ + + + W D R L
Sbjct: 1465 LAVDRSDGYVYWVDDSLDIIARIRINGENSEVIRYGSRYPTPYGITVFENSIIWVD-RNL 1523
Query: 435 K 437
K
Sbjct: 1524 K 1524
Score = 31.1 bits (67), Expect = 3.3
Identities = 21/60 (35%), Positives = 32/60 (53%)
Frame = +1
Query: 76 VRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDGTERSVLLGSPDVKLP 255
V++V ++ + P GIAV I+W+D N +IE A +DG R L+ S D+ P
Sbjct: 3357 VQEVDLKLKYVMQPDGIAVDWVGRHIYWSD--VKNKRIEVAKLDGRYRKWLI-STDLDQP 3413
Score = 30.7 bits (66), Expect = 4.4
Identities = 17/63 (26%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDL---HSRQIETIAENCRYPFGLAINGDKLYWSDWRT 431
+ ID+ + F D+ L + D H RQ+ R+P+ L + D +YW+D T
Sbjct: 829 LTIDYPNRLLYFMDSYLDYMDFCDYNGHHRRQVIASDLIIRHPYALTLFEDSVYWTDRAT 888
Query: 432 LKI 440
++
Sbjct: 889 RRV 891
Score = 30.7 bits (66), Expect = 4.4
Identities = 18/55 (32%), Positives = 30/55 (54%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTD 165
D + ++W + + IE N+D R +L V +S+P GIAVH +++TD
Sbjct: 1153 DIEEQKLYWAVTGRGVIERGNVDGTDRMIL--VHQLSHPWGIAVHD--SFLYYTD 1203
>AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor
gp330/megalin precursor protein.
Length = 4655
Score = 77.8 bits (183), Expect = 3e-14
Identities = 36/79 (45%), Positives = 56/79 (70%), Gaps = 2/79 (2%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGK--IFWTDWNR 174
DW RN++WTD TIEV+ +D R VL S +N++NPRG+A+ P+ + +FW+DW
Sbjct: 1517 DWVGRNLYWTDYALETIEVSKIDGSHRTVLIS-KNLTNPRGLALDPRMNEHLLFWSDWGH 1575
Query: 175 SNPKIEWANMDGTERSVLL 231
+P+IE A+MDG+ R+V++
Sbjct: 1576 -HPRIERASMDGSMRTVIV 1593
Score = 77.8 bits (183), Expect = 3e-14
Identities = 39/86 (45%), Positives = 56/86 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW R+I+W+D K IEVA LD + RK L S ++ P IAV+P+ G +FWTDW +
Sbjct: 4150 DWVGRHIYWSDVKNKRIEVAKLDGRYRKWLIST-DLDQPAAIAVNPKLGLMFWTDWGK-E 4207
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPT 258
PK+E A M+G +R++L+ D+ PT
Sbjct: 4208 PKLESAWMNGEDRNILV-FEDLGWPT 4232
Score = 62.5 bits (145), Expect = 1e-09
Identities = 31/71 (43%), Positives = 44/71 (61%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++N++WTDS +I V L K R+ + VQ ++NPR + VHP G +F+TDW R
Sbjct: 792 DWISKNLYWTDSHYKSISVMRLADKTRRTV--VQYLNNPRSVVVHPFAGYLFFTDWFRP- 848
Query: 181 PKIEWANMDGT 213
KI A DG+
Sbjct: 849 AKIMRAWSDGS 859
Score = 60.5 bits (140), Expect = 5e-09
Identities = 35/92 (38%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN--R 174
DW I+ ++K I++ NLD R L + +N+ +PRGIAV P G +F++DW
Sbjct: 475 DWVNNKIYLVETKVNRIDMVNLDGSYRVTLIT-ENLGHPRGIAVDPTVGYLFFSDWESLS 533
Query: 175 SNPKIEWANMDGTERSVLLGSPDVKLPTLWPS 270
PK+E A MDG+ R L VK WP+
Sbjct: 534 GEPKLERAFMDGSNRKDL-----VKTKLGWPA 560
Score = 57.6 bits (133), Expect = 3e-08
Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 7/86 (8%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVL----FSVQN---ISNPRGIAVHPQRGKIFW 159
DW +R ++W D++ + V++L+ R++L N NPRG+A+HPQ G ++W
Sbjct: 3278 DWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYW 3337
Query: 160 TDWNRSNPKIEWANMDGTERSVLLGS 237
DW I MDGT +SV++ +
Sbjct: 3338 ADWGH-RAYIGRVGMDGTNKSVIIST 3362
Score = 52.8 bits (121), Expect = 1e-06
Identities = 32/85 (37%), Positives = 45/85 (52%), Gaps = 9/85 (10%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANL--DTKVRKVLFS----VQNISNPRGIAVHPQRGKIFWT 162
DW +RN++ T+ + +IEV L D + RK L + + P GI V P RGK++W+
Sbjct: 1829 DWISRNLYSTNPRTQSIEVLTLHGDIRYRKTLIANDGTALGVGFPIGITVDPARGKLYWS 1888
Query: 163 DWNRSN---PKIEWANMDGTERSVL 228
D + KI ANMDGT L
Sbjct: 1889 DQGTDSGVPAKIASANMDGTSVKTL 1913
Score = 49.6 bits (113), Expect = 9e-06
Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +3
Query: 240 RCEASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCR-YPFGLAINGDKLYW 416
+ E N + ID++ D + +ADA L I+ DL T+ + +PF + I D +YW
Sbjct: 3363 KLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDGALPHPFAITIFEDTIYW 3422
Query: 417 SDWRTLKIE 443
+DW T +E
Sbjct: 3423 TDWNTRTVE 3431
Score = 44.0 bits (99), Expect = 4e-04
Identities = 24/79 (30%), Positives = 39/79 (49%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW R I+++D I D R V + + PR I + P +G ++W DW+ ++
Sbjct: 2474 DWITRRIYYSDYLNQMINSMAEDGSNRTV---IARVPKPRAIVLDPCQGYLYWADWD-TH 2529
Query: 181 PKIEWANMDGTERSVLLGS 237
KIE A + G R ++ S
Sbjct: 2530 AKIERATLGGNFRVPIVNS 2548
Score = 43.6 bits (98), Expect = 6e-04
Identities = 25/61 (40%), Positives = 37/61 (60%), Gaps = 3/61 (4%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIK--CID-LHSRQIETIAENCRYPFGLAINGDKLYWSDW 425
N +AIDW+ R+ + DA I+ D L R++ I E +PFGLAI G+ L+++DW
Sbjct: 873 NGLAIDWAASRLYWVDAYFDKIEHSTFDGLDRRRLGHI-EQMTHPFGLAIFGEHLFFTDW 931
Query: 426 R 428
R
Sbjct: 932 R 932
Score = 42.7 bits (96), Expect = 0.001
Identities = 23/76 (30%), Positives = 41/76 (53%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW+A ++W D+ IE + D R+ L ++ +++P G+A+ + +F+TDW R
Sbjct: 878 DWAASRLYWVDAYFDKIEHSTFDGLDRRRLGHIEQMTHPFGLAIFGEH--LFFTDW-RLG 934
Query: 181 PKIEWANMDGTERSVL 228
I DG E +V+
Sbjct: 935 AIIRVRKADGGEMTVI 950
Score = 37.9 bits (84), Expect = 0.029
Identities = 19/62 (30%), Positives = 31/62 (50%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
+ + +D+ D + + DA LQ I+ L E I + FGL + G +YW+D T
Sbjct: 2554 SGLTLDYEEDLLYWVDASLQRIERSTLTGVDREVIVNAAVHAFGLTLYGQYIYWTDLYTQ 2613
Query: 435 KI 440
+I
Sbjct: 2614 RI 2615
Score = 37.5 bits (83), Expect = 0.038
Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Frame = +1
Query: 13 RNIFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTD 165
R +FW D ++ IE + LD R VL S + I PRG+AV G ++W D
Sbjct: 2202 RYLFWADYGQRPKIERSFLDCTNRTVLVS-EGIVTPRGLAVDRSDGYVYWVD 2252
Score = 35.1 bits (77), Expect = 0.21
Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 5/63 (7%)
Frame = +3
Query: 252 SNSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAI----NGDKLYW 416
+ ++AIDW + + D L+ I+ + S + I++N P GLA+ N L+W
Sbjct: 1511 TETIAIDWVGRNLYWTDYALETIEVSKIDGSHRTVLISKNLTNPRGLALDPRMNEHLLFW 1570
Query: 417 SDW 425
SDW
Sbjct: 1571 SDW 1573
Score = 34.7 bits (76), Expect = 0.27
Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRK-VLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
D ++ ++W DS+ IE D RK V+ I +P G+++ G++F+TDW +
Sbjct: 565 DMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLF--EGQVFFTDWTK 621
Score = 33.9 bits (74), Expect = 0.47
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 11/73 (15%)
Frame = +3
Query: 240 RCEASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENC---------RYPFGLA 392
R A+ S+A+DW ++ + DA L + DL+ +A++C P GLA
Sbjct: 3268 RLPAAESLAVDWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLA 3327
Query: 393 INGD--KLYWSDW 425
++ LYW+DW
Sbjct: 3328 LHPQYGYLYWADW 3340
Score = 32.3 bits (70), Expect = 1.4
Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D++ ++W D+ IE ++L+ R ++ + +P I + I+WTDWN
Sbjct: 3373 DYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDGA-LPHPFAITIFEDT--IYWTDWNTRT 3429
Query: 181 PKIEWAN-MDGTERSVLLGS 237
+E N DG+ R L+ +
Sbjct: 3430 --VEKGNKYDGSNRQTLVNT 3447
Score = 31.1 bits (67), Expect = 3.3
Identities = 19/61 (31%), Positives = 32/61 (52%)
Frame = +1
Query: 49 IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDGTERSVL 228
I AN+D K LF+ N+ + + + + K++W R IE N+DGT+R +L
Sbjct: 1900 IASANMDGTSVKTLFT-GNLEHLECVTLDIEEQKLYWAVTGRG--VIERGNVDGTDRMIL 1956
Query: 229 L 231
+
Sbjct: 1957 V 1957
Score = 31.1 bits (67), Expect = 3.3
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRY--PFGLAINGDKLYWSDWRTL 434
+A+D S V + D L +I I ++ E I RY P+G+ + + + W D R L
Sbjct: 2239 LAVDRSDGYVYWVDDSLDIIARIRINGENSEVIRYGSRYPTPYGITVFENSIIWVD-RNL 2297
Query: 435 K 437
K
Sbjct: 2298 K 2298
Score = 31.1 bits (67), Expect = 3.3
Identities = 21/60 (35%), Positives = 32/60 (53%)
Frame = +1
Query: 76 VRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDGTERSVLLGSPDVKLP 255
V++V ++ + P GIAV I+W+D N +IE A +DG R L+ S D+ P
Sbjct: 4131 VQEVDLKLKYVMQPDGIAVDWVGRHIYWSD--VKNKRIEVAKLDGRYRKWLI-STDLDQP 4187
Score = 30.7 bits (66), Expect = 4.4
Identities = 17/63 (26%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDL---HSRQIETIAENCRYPFGLAINGDKLYWSDWRT 431
+ ID+ + F D+ L + D H RQ+ R+P+ L + D +YW+D T
Sbjct: 1603 LTIDYPNRLLYFMDSYLDYMDFCDYNGHHRRQVIASDLIIRHPYALTLFEDSVYWTDRAT 1662
Query: 432 LKI 440
++
Sbjct: 1663 RRV 1665
Score = 30.7 bits (66), Expect = 4.4
Identities = 18/55 (32%), Positives = 30/55 (54%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTD 165
D + ++W + + IE N+D R +L V +S+P GIAVH +++TD
Sbjct: 1927 DIEEQKLYWAVTGRGVIERGNVDGTDRMIL--VHQLSHPWGIAVHD--SFLYYTD 1977
Score = 29.9 bits (64), Expect = 7.7
Identities = 15/76 (19%), Positives = 36/76 (47%), Gaps = 3/76 (3%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN---CRYPFGLAINGDKLYWSDWRT 431
V +D RV + D+ I+ + Q +T+ +PFG+++ +++++DW
Sbjct: 562 VTLDMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTK 621
Query: 432 LKIEIIDTITQARGQI 479
+ + + T+ Q+
Sbjct: 622 MAVLKANKFTETNPQV 637
>AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor
gp330/megalin precursor protein.
Length = 4655
Score = 77.8 bits (183), Expect = 3e-14
Identities = 36/79 (45%), Positives = 56/79 (70%), Gaps = 2/79 (2%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGK--IFWTDWNR 174
DW RN++WTD TIEV+ +D R VL S +N++NPRG+A+ P+ + +FW+DW
Sbjct: 1517 DWVGRNLYWTDYALETIEVSKIDGSHRTVLIS-KNLTNPRGLALDPRMNEHLLFWSDWGH 1575
Query: 175 SNPKIEWANMDGTERSVLL 231
+P+IE A+MDG+ R+V++
Sbjct: 1576 -HPRIERASMDGSMRTVIV 1593
Score = 76.6 bits (180), Expect = 7e-14
Identities = 39/86 (45%), Positives = 55/86 (63%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW R+I+W+D K IEVA LD + RK L S ++ P IAV+P+ G +FWTDW +
Sbjct: 4150 DWVGRHIYWSDVKNKRIEVAKLDGRYRKWLIST-DLDQPAAIAVNPKLGLMFWTDWGK-E 4207
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPT 258
PK E A M+G +R++L+ D+ PT
Sbjct: 4208 PKXESAWMNGEDRNILV-FEDLGWPT 4232
Score = 62.5 bits (145), Expect = 1e-09
Identities = 31/71 (43%), Positives = 44/71 (61%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++N++WTDS +I V L K R+ + VQ ++NPR + VHP G +F+TDW R
Sbjct: 792 DWISKNLYWTDSHYKSISVMRLADKTRRTV--VQYLNNPRSVVVHPFAGYLFFTDWFRP- 848
Query: 181 PKIEWANMDGT 213
KI A DG+
Sbjct: 849 AKIMRAWSDGS 859
Score = 60.5 bits (140), Expect = 5e-09
Identities = 35/92 (38%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN--R 174
DW I+ ++K I++ NLD R L + +N+ +PRGIAV P G +F++DW
Sbjct: 475 DWVNNKIYLVETKVNRIDMVNLDGSYRVTLIT-ENLGHPRGIAVDPTVGYLFFSDWESLS 533
Query: 175 SNPKIEWANMDGTERSVLLGSPDVKLPTLWPS 270
PK+E A MDG+ R L VK WP+
Sbjct: 534 GEPKLERAFMDGSNRKDL-----VKTKLGWPA 560
Score = 57.6 bits (133), Expect = 3e-08
Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 7/86 (8%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVL----FSVQN---ISNPRGIAVHPQRGKIFW 159
DW +R ++W D++ + V++L+ R++L N NPRG+A+HPQ G ++W
Sbjct: 3278 DWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYW 3337
Query: 160 TDWNRSNPKIEWANMDGTERSVLLGS 237
DW I MDGT +SV++ +
Sbjct: 3338 ADWGH-RAYIGRVGMDGTNKSVIIST 3362
Score = 52.8 bits (121), Expect = 1e-06
Identities = 32/85 (37%), Positives = 45/85 (52%), Gaps = 9/85 (10%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANL--DTKVRKVLFS----VQNISNPRGIAVHPQRGKIFWT 162
DW +RN++ T+ + +IEV L D + RK L + + P GI V P RGK++W+
Sbjct: 1829 DWISRNLYSTNPRTQSIEVLTLHGDIRYRKTLIANDGTALGVGFPIGITVDPARGKLYWS 1888
Query: 163 DWNRSN---PKIEWANMDGTERSVL 228
D + KI ANMDGT L
Sbjct: 1889 DQGTDSGVPAKIASANMDGTSVKTL 1913
Score = 49.6 bits (113), Expect = 9e-06
Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +3
Query: 240 RCEASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCR-YPFGLAINGDKLYW 416
+ E N + ID++ D + +ADA L I+ DL T+ + +PF + I D +YW
Sbjct: 3363 KLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDGALPHPFAITIFEDTIYW 3422
Query: 417 SDWRTLKIE 443
+DW T +E
Sbjct: 3423 TDWNTRTVE 3431
Score = 44.0 bits (99), Expect = 4e-04
Identities = 24/79 (30%), Positives = 39/79 (49%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW R I+++D I D R V + + PR I + P +G ++W DW+ ++
Sbjct: 2474 DWITRRIYYSDYLNQMINSMAEDGSNRTV---IARVPKPRAIVLDPCQGYLYWADWD-TH 2529
Query: 181 PKIEWANMDGTERSVLLGS 237
KIE A + G R ++ S
Sbjct: 2530 AKIERATLGGNFRVPIVNS 2548
Score = 43.6 bits (98), Expect = 6e-04
Identities = 25/61 (40%), Positives = 37/61 (60%), Gaps = 3/61 (4%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIK--CID-LHSRQIETIAENCRYPFGLAINGDKLYWSDW 425
N +AIDW+ R+ + DA I+ D L R++ I E +PFGLAI G+ L+++DW
Sbjct: 873 NGLAIDWAASRLYWVDAYFDKIEHSTFDGLDRRRLGHI-EQMTHPFGLAIFGEHLFFTDW 931
Query: 426 R 428
R
Sbjct: 932 R 932
Score = 42.7 bits (96), Expect = 0.001
Identities = 23/76 (30%), Positives = 41/76 (53%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW+A ++W D+ IE + D R+ L ++ +++P G+A+ + +F+TDW R
Sbjct: 878 DWAASRLYWVDAYFDKIEHSTFDGLDRRRLGHIEQMTHPFGLAIFGEH--LFFTDW-RLG 934
Query: 181 PKIEWANMDGTERSVL 228
I DG E +V+
Sbjct: 935 AIIRVRKADGGEMTVI 950
Score = 37.9 bits (84), Expect = 0.029
Identities = 19/62 (30%), Positives = 31/62 (50%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
+ + +D+ D + + DA LQ I+ L E I + FGL + G +YW+D T
Sbjct: 2554 SGLTLDYEEDLLYWVDASLQRIERSTLTGVDREVIVNAAVHAFGLTLYGQYIYWTDLYTQ 2613
Query: 435 KI 440
+I
Sbjct: 2614 RI 2615
Score = 37.5 bits (83), Expect = 0.038
Identities = 21/52 (40%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Frame = +1
Query: 13 RNIFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTD 165
R +FW D ++ IE + LD R VL S + I PRG+AV G ++W D
Sbjct: 2202 RYLFWADYGQRPKIERSFLDCTNRTVLVS-EGIVTPRGLAVDRSDGYVYWVD 2252
Score = 35.1 bits (77), Expect = 0.21
Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 5/63 (7%)
Frame = +3
Query: 252 SNSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAI----NGDKLYW 416
+ ++AIDW + + D L+ I+ + S + I++N P GLA+ N L+W
Sbjct: 1511 TETIAIDWVGRNLYWTDYALETIEVSKIDGSHRTVLISKNLTNPRGLALDPRMNEHLLFW 1570
Query: 417 SDW 425
SDW
Sbjct: 1571 SDW 1573
Score = 34.7 bits (76), Expect = 0.27
Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRK-VLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
D ++ ++W DS+ IE D RK V+ I +P G+++ G++F+TDW +
Sbjct: 565 DMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLF--EGQVFFTDWTK 621
Score = 33.9 bits (74), Expect = 0.47
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 11/73 (15%)
Frame = +3
Query: 240 RCEASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENC---------RYPFGLA 392
R A+ S+A+DW ++ + DA L + DL+ +A++C P GLA
Sbjct: 3268 RLPAAESLAVDWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLA 3327
Query: 393 INGD--KLYWSDW 425
++ LYW+DW
Sbjct: 3328 LHPQYGYLYWADW 3340
Score = 32.3 bits (70), Expect = 1.4
Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D++ ++W D+ IE ++L+ R ++ + +P I + I+WTDWN
Sbjct: 3373 DYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDGA-LPHPFAITIFEDT--IYWTDWNTRT 3429
Query: 181 PKIEWAN-MDGTERSVLLGS 237
+E N DG+ R L+ +
Sbjct: 3430 --VEKGNKYDGSNRQTLVNT 3447
Score = 31.1 bits (67), Expect = 3.3
Identities = 19/61 (31%), Positives = 32/61 (52%)
Frame = +1
Query: 49 IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDGTERSVL 228
I AN+D K LF+ N+ + + + + K++W R IE N+DGT+R +L
Sbjct: 1900 IASANMDGTSVKTLFT-GNLEHLECVTLDIEEQKLYWAVTGRG--VIERGNVDGTDRMIL 1956
Query: 229 L 231
+
Sbjct: 1957 V 1957
Score = 31.1 bits (67), Expect = 3.3
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRY--PFGLAINGDKLYWSDWRTL 434
+A+D S V + D L +I I ++ E I RY P+G+ + + + W D R L
Sbjct: 2239 LAVDRSDGYVYWVDDSLDIIARIRINGENSEVIRYGSRYPTPYGITVFENSIIWVD-RNL 2297
Query: 435 K 437
K
Sbjct: 2298 K 2298
Score = 31.1 bits (67), Expect = 3.3
Identities = 21/60 (35%), Positives = 32/60 (53%)
Frame = +1
Query: 76 VRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDGTERSVLLGSPDVKLP 255
V++V ++ + P GIAV I+W+D N +IE A +DG R L+ S D+ P
Sbjct: 4131 VQEVDLKLKYVMQPDGIAVDWVGRHIYWSD--VKNKRIEVAKLDGRYRKWLI-STDLDQP 4187
Score = 30.7 bits (66), Expect = 4.4
Identities = 17/63 (26%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDL---HSRQIETIAENCRYPFGLAINGDKLYWSDWRT 431
+ ID+ + F D+ L + D H RQ+ R+P+ L + D +YW+D T
Sbjct: 1603 LTIDYPNRLLYFMDSYLDYMDFCDYNGHHRRQVIASDLIIRHPYALTLFEDSVYWTDRAT 1662
Query: 432 LKI 440
++
Sbjct: 1663 RRV 1665
Score = 30.7 bits (66), Expect = 4.4
Identities = 18/55 (32%), Positives = 30/55 (54%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTD 165
D + ++W + + IE N+D R +L V +S+P GIAVH +++TD
Sbjct: 1927 DIEEQKLYWAVTGRGVIERGNVDGTDRMIL--VHQLSHPWGIAVHD--SFLYYTD 1977
Score = 29.9 bits (64), Expect = 7.7
Identities = 15/76 (19%), Positives = 36/76 (47%), Gaps = 3/76 (3%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN---CRYPFGLAINGDKLYWSDWRT 431
V +D RV + D+ I+ + Q +T+ +PFG+++ +++++DW
Sbjct: 562 VTLDMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTK 621
Query: 432 LKIEIIDTITQARGQI 479
+ + + T+ Q+
Sbjct: 622 MAVLKANKFTETNPQV 637
>AF283374-1|AAL38108.1| 1731|Homo sapiens candidate tumor suppressor
protein protein.
Length = 1731
Score = 77.0 bits (181), Expect = 5e-14
Identities = 42/97 (43%), Positives = 58/97 (59%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW A NI+WTD IEVA L+ R V+ S Q + PR IAVHP++G +FWT+W +
Sbjct: 1037 DWIAGNIYWTDHGFNLIEVARLNGSFRYVIIS-QGLDQPRSIAVHPEKGLLFWTEWGQM- 1094
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPTLWPSTGREIEF 291
P I A +DG+E+ VL V + WP+ G I++
Sbjct: 1095 PCIGKARLDGSEKVVL-----VSMGIAWPN-GISIDY 1125
Score = 72.9 bits (171), Expect = 8e-13
Identities = 38/90 (42%), Positives = 53/90 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW A NI+W DS IEVA LD +R L + + +PR IA+ P+ G +FWTDW+ +
Sbjct: 419 DWIAGNIYWIDSNLDQIEVAKLDGSLRTTLIAGA-MEHPRAIALDPRYGILFWTDWDANF 477
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPTLWPS 270
P+IE A+M G R + D+K WP+
Sbjct: 478 PRIESASMSGAGRKTIY--KDMKTGA-WPN 504
Score = 60.1 bits (139), Expect = 6e-09
Identities = 30/78 (38%), Positives = 45/78 (57%), Gaps = 2/78 (2%)
Frame = +1
Query: 1 DWSARNIFWTDSK--KLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
DW +RN++W S+ + I VA LD ++ + + I P+ +A HP RGK++WTD N
Sbjct: 733 DWVSRNLYWISSEFDETQINVARLDGSLKTSI--IHGIDKPQCLAAHPVRGKLYWTDGN- 789
Query: 175 SNPKIEWANMDGTERSVL 228
I ANMDG+ +L
Sbjct: 790 ---TINMANMDGSNSKIL 804
Score = 41.1 bits (92), Expect = 0.003
Identities = 23/70 (32%), Positives = 36/70 (51%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
++WTD TI +AN+D K+LF QN P G+++ K++W + N I
Sbjct: 783 LYWTDGN--TINMANMDGSNSKILF--QNQKEPVGLSIDYVENKLYWI--SSGNGTINRC 836
Query: 199 NMDGTERSVL 228
N+DG V+
Sbjct: 837 NLDGGNLEVI 846
Score = 37.1 bits (82), Expect = 0.051
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVI-KCIDLHSRQIETIA--ENCRYPFGLAINGDKLYWSDW 425
N + +D R+ + DA I + + IE I E +PF +++ G ++YW+DW
Sbjct: 504 NGLTVDHFEKRIVWTDARSDAIYSALYDGTNMIEIIRGHEYLSHPFAVSLYGSEVYWTDW 563
Query: 426 RT 431
RT
Sbjct: 564 RT 565
Score = 36.7 bits (81), Expect = 0.067
Identities = 21/84 (25%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLD-TKV----RKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNP 183
++WT S +I +D T+ R+ + ++ +P +A+ + +FWT+WN +P
Sbjct: 1359 LYWTSSTTSSITRHTVDQTRPGAFDREAVITMSEDDHPHVLALDECQNLMFWTNWNEQHP 1418
Query: 184 KIEWANMDGTERSVLLGSPDVKLP 255
I + + G V++ S D+ P
Sbjct: 1419 SIMRSTLTGKNAQVVV-STDILTP 1441
Score = 35.5 bits (78), Expect = 0.16
Identities = 21/81 (25%), Positives = 41/81 (50%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D S ++WTD K TI+ A ++ + + S ++I + RG+AV ++W
Sbjct: 690 DASEERLYWTDIKTQTIKRAFINGTGLETVIS-RDIQSIRGLAVDWVSRNLYWISSEFDE 748
Query: 181 PKIEWANMDGTERSVLLGSPD 243
+I A +DG+ ++ ++ D
Sbjct: 749 TQINVARLDGSLKTSIIHGID 769
Score = 35.1 bits (77), Expect = 0.21
Identities = 24/80 (30%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Frame = +1
Query: 19 IFWTDSKKLT-IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
+FWT+ ++ I A LD + VL S+ I+ P GI++ + K++W D KIE
Sbjct: 1086 LFWTEWGQMPCIGKARLDGSEKVVLVSM-GIAWPNGISIDYEENKLYWCD--ARTDKIER 1142
Query: 196 ANMD-GTERSVLLGSPDVKL 252
+++ G R ++L +V +
Sbjct: 1143 IDLETGGNREMVLSGSNVDM 1162
Score = 32.7 bits (71), Expect = 1.1
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%)
Frame = +1
Query: 1 DWSARN--IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
D+ A N I+WTD I A D ++ + + + GIAV G I+WTD
Sbjct: 992 DFHAENDTIYWTDMGFNKISRAKRDQTWKEDIIT-NGLGRVEGIAVDWIAGNIYWTDHGF 1050
Query: 175 SNPKIEWANMDGTERSVLL 231
+ IE A ++G+ R V++
Sbjct: 1051 N--LIEVARLNGSFRYVII 1067
Score = 32.7 bits (71), Expect = 1.1
Identities = 16/58 (27%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPF-GLAINGDKLYWSDW 425
N + ID+ +++ F+D L I+ + Q I ++ F LA+ + ++WSDW
Sbjct: 1442 NGLTIDYRAEKLYFSDGSLGKIERCEYDGSQRHVIVKSGPGTFLSLAVYDNYIFWSDW 1499
Score = 32.3 bits (70), Expect = 1.4
Identities = 20/77 (25%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLD-TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRS 177
D + I WTD++ I A D T + +++ + +S+P ++++ +++WTDW R+
Sbjct: 509 DHFEKRIVWTDARSDAIYSALYDGTNMIEIIRGHEYLSHPFAVSLYGS--EVYWTDW-RT 565
Query: 178 NPKIEWANMDGTERSVL 228
N + G SV+
Sbjct: 566 NTLSKANKWTGQNVSVI 582
Score = 32.3 bits (70), Expect = 1.4
Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Frame = +3
Query: 339 SRQIETIAENCRYPFGLAINGD--KLYWSDWRTLKIEIIDTITQARGQIDIPRSTI 500
S ++ ++ +P G++I+ + KLYW D RT KIE ID T ++ + S +
Sbjct: 1105 SEKVVLVSMGIAWPNGISIDYEENKLYWCDARTDKIERIDLETGGNREMVLSGSNV 1160
Score = 31.5 bits (68), Expect = 2.5
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTK--VRKVLFSVQN-ISNPRGIAVHPQRGKIFWTDWNRSNPKI 189
++WTD + I L V + V++ ++ P G+ V G I+W D N +I
Sbjct: 378 LYWTDVVEDRIYRGKLSESGGVSAIEVVVEHGLATPEGLTVDWIAGNIYWIDSNLD--QI 435
Query: 190 EWANMDGTERSVLL 231
E A +DG+ R+ L+
Sbjct: 436 EVAKLDGSLRTTLI 449
Score = 30.3 bits (65), Expect = 5.8
Identities = 18/59 (30%), Positives = 31/59 (52%), Gaps = 3/59 (5%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLH---SRQIETIAENCRYPFGLAINGDKLYWSD 422
N ++ID+ +++ + DA I+ IDL +R++ N F +A G +YWSD
Sbjct: 1119 NGISIDYEENKLYWCDARTDKIERIDLETGGNREMVLSGSNVDM-FSVAXFGAYIYWSD 1176
>AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein
receptor related protein-deleted in tumor protein.
Length = 4599
Score = 77.0 bits (181), Expect = 5e-14
Identities = 42/97 (43%), Positives = 58/97 (59%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW A NI+WTD IEVA L+ R V+ S Q + PR IAVHP++G +FWT+W +
Sbjct: 1961 DWIAGNIYWTDHGFNLIEVARLNGSFRYVIIS-QGLDQPRSIAVHPEKGLLFWTEWGQM- 2018
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPTLWPSTGREIEF 291
P I A +DG+E+ VL V + WP+ G I++
Sbjct: 2019 PCIGKARLDGSEKVVL-----VSMGIAWPN-GISIDY 2049
Score = 72.9 bits (171), Expect = 8e-13
Identities = 38/90 (42%), Positives = 53/90 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW A NI+W DS IEVA LD +R L + + +PR IA+ P+ G +FWTDW+ +
Sbjct: 1343 DWIAGNIYWIDSNLDQIEVAKLDGSLRTTLIAGA-MEHPRAIALDPRYGILFWTDWDANF 1401
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPTLWPS 270
P+IE A+M G R + D+K WP+
Sbjct: 1402 PRIESASMSGAGRKTIY--KDMKTGA-WPN 1428
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/105 (38%), Positives = 57/105 (54%), Gaps = 8/105 (7%)
Frame = +1
Query: 1 DWSARNIFWT-DSKKLTIEVANLD--TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN 171
DW N++WT D + TI VA L+ ++ RK L + +S+PRGI V P G ++WTDW
Sbjct: 607 DWIGNNLYWTNDGHRKTINVARLEKASQSRKTLLEGE-MSHPRGIVVDPVNGWMYWTDWE 665
Query: 172 R-----SNPKIEWANMDGTERSVLLGSPDVKLPTLWPSTGREIEF 291
S +IE A MDG R + + S LWP+ G ++F
Sbjct: 666 EDEIDDSVGRIEKAWMDGFNRQIFVTS-----KMLWPN-GLTLDF 704
Score = 60.1 bits (139), Expect = 6e-09
Identities = 30/78 (38%), Positives = 45/78 (57%), Gaps = 2/78 (2%)
Frame = +1
Query: 1 DWSARNIFWTDSK--KLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
DW +RN++W S+ + I VA LD ++ + + I P+ +A HP RGK++WTD N
Sbjct: 1657 DWVSRNLYWISSEFDETQINVARLDGSLKTSI--IHGIDKPQCLAAHPVRGKLYWTDGN- 1713
Query: 175 SNPKIEWANMDGTERSVL 228
I ANMDG+ +L
Sbjct: 1714 ---TINMANMDGSNSKIL 1728
Score = 56.8 bits (131), Expect = 6e-08
Identities = 27/77 (35%), Positives = 46/77 (59%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW +N++W+D++K IEV+ L+ +L S + + PR +++ PQ G ++W D
Sbjct: 3095 DWIGKNLYWSDTEKRIIEVSKLNGLYPTILVS-KRLKFPRDLSLDPQAGYLYWIDC-CEY 3152
Query: 181 PKIEWANMDGTERSVLL 231
P I MDGT +SV++
Sbjct: 3153 PHIGRVGMDGTNQSVVI 3169
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/79 (35%), Positives = 45/79 (56%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW RN+++ D I V N + V L ++ + NP+ IAV P GK+F+TD+ +
Sbjct: 291 DWLTRNLYFVDHVGDRIFVCNSNGSVCVTLIDLE-LHNPKAIAVDPIAGKLFFTDYG-NV 348
Query: 181 PKIEWANMDGTERSVLLGS 237
K+E +MDG R+ ++ S
Sbjct: 349 AKVERCDMDGMNRTRIIDS 367
Score = 41.1 bits (92), Expect = 0.003
Identities = 23/70 (32%), Positives = 36/70 (51%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
++WTD TI +AN+D K+LF QN P G+++ K++W + N I
Sbjct: 1707 LYWTDGN--TINMANMDGSNSKILF--QNQKEPVGLSIDYVENKLYWI--SSGNGTINRC 1760
Query: 199 NMDGTERSVL 228
N+DG V+
Sbjct: 1761 NLDGGNLEVI 1770
Score = 39.5 bits (88), Expect = 0.010
Identities = 31/100 (31%), Positives = 48/100 (48%), Gaps = 14/100 (14%)
Frame = +1
Query: 1 DWSARNIFWTDSKKL------TIEVANLDTKVRKVLFSVQNISN--------PRGIAVHP 138
DW A NI+WTD ++ T +L + + N + P IAV+P
Sbjct: 3977 DWVAGNIYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNMAGEPYAIAVNP 4036
Query: 139 QRGKIFWTDWNRSNPKIEWANMDGTERSVLLGSPDVKLPT 258
+RG ++WT + IE A MDGT R +L+ +++ PT
Sbjct: 4037 KRGMMYWTVVG-DHSHIEEAAMDGTLRRILV-QKNLQRPT 4074
Score = 37.1 bits (82), Expect = 0.051
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVI-KCIDLHSRQIETIA--ENCRYPFGLAINGDKLYWSDW 425
N + +D R+ + DA I + + IE I E +PF +++ G ++YW+DW
Sbjct: 1428 NGLTVDHFEKRIVWTDARSDAIYSALYDGTNMIEIIRGHEYLSHPFAVSLYGSEVYWTDW 1487
Query: 426 RT 431
RT
Sbjct: 1488 RT 1489
Score = 36.7 bits (81), Expect = 0.067
Identities = 21/84 (25%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLD-TKV----RKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNP 183
++WT S +I +D T+ R+ + ++ +P +A+ + +FWT+WN +P
Sbjct: 2283 LYWTSSTTSSITRHTVDQTRPGAFDREAVITMSEDDHPHVLALDECQNLMFWTNWNEQHP 2342
Query: 184 KIEWANMDGTERSVLLGSPDVKLP 255
I + + G V++ S D+ P
Sbjct: 2343 SIMRSTLTGKNAQVVV-STDILTP 2365
Score = 35.5 bits (78), Expect = 0.16
Identities = 16/56 (28%), Positives = 32/56 (57%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDW 168
D+ ++W D+ IE L+ RK+++S + +++P G++ H +FWTD+
Sbjct: 703 DFHTNTLYWCDAYYDHIEKVFLNGTHRKIVYSGRELNHPFGLSHH--GNYVFWTDY 756
Score = 35.5 bits (78), Expect = 0.16
Identities = 21/81 (25%), Positives = 41/81 (50%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D S ++WTD K TI+ A ++ + + S ++I + RG+AV ++W
Sbjct: 1614 DASEERLYWTDIKTQTIKRAFINGTGLETVIS-RDIQSIRGLAVDWVSRNLYWISSEFDE 1672
Query: 181 PKIEWANMDGTERSVLLGSPD 243
+I A +DG+ ++ ++ D
Sbjct: 1673 TQINVARLDGSLKTSIIHGID 1693
Score = 35.1 bits (77), Expect = 0.21
Identities = 24/80 (30%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Frame = +1
Query: 19 IFWTDSKKLT-IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
+FWT+ ++ I A LD + VL S+ I+ P GI++ + K++W D KIE
Sbjct: 2010 LFWTEWGQMPCIGKARLDGSEKVVLVSM-GIAWPNGISIDYEENKLYWCD--ARTDKIER 2066
Query: 196 ANMD-GTERSVLLGSPDVKL 252
+++ G R ++L +V +
Sbjct: 2067 IDLETGGNREMVLSGSNVDM 2086
Score = 34.7 bits (76), Expect = 0.27
Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHS--RQIETIAENCRYPFGLAINGDKLYWSDWR 428
N + +D+ + + + DA I+ + L+ R+I +PFGL+ +G+ ++W+D+
Sbjct: 698 NGLTLDFHTNTLYWCDAYYDHIEKVFLNGTHRKIVYSGRELNHPFGLSHHGNYVFWTDYM 757
Query: 429 TLKIEIIDTIT 461
I +D IT
Sbjct: 758 NGSIFQLDLIT 768
Score = 32.7 bits (71), Expect = 1.1
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%)
Frame = +1
Query: 1 DWSARN--IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
D+ A N I+WTD I A D ++ + + + GIAV G I+WTD
Sbjct: 1916 DFHAENDTIYWTDMGFNKISRAKRDQTWKEDIIT-NGLGRVEGIAVDWIAGNIYWTDHGF 1974
Query: 175 SNPKIEWANMDGTERSVLL 231
+ IE A ++G+ R V++
Sbjct: 1975 N--LIEVARLNGSFRYVII 1991
Score = 32.7 bits (71), Expect = 1.1
Identities = 16/58 (27%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPF-GLAINGDKLYWSDW 425
N + ID+ +++ F+D L I+ + Q I ++ F LA+ + ++WSDW
Sbjct: 2366 NGLTIDYRAEKLYFSDGSLGKIERCEYDGSQRHVIVKSGPGTFLSLAVYDNYIFWSDW 2423
Score = 32.3 bits (70), Expect = 1.4
Identities = 20/77 (25%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLD-TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRS 177
D + I WTD++ I A D T + +++ + +S+P ++++ +++WTDW R+
Sbjct: 1433 DHFEKRIVWTDARSDAIYSALYDGTNMIEIIRGHEYLSHPFAVSLYGS--EVYWTDW-RT 1489
Query: 178 NPKIEWANMDGTERSVL 228
N + G SV+
Sbjct: 1490 NTLSKANKWTGQNVSVI 1506
Score = 32.3 bits (70), Expect = 1.4
Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Frame = +3
Query: 339 SRQIETIAENCRYPFGLAINGD--KLYWSDWRTLKIEIIDTITQARGQIDIPRSTI 500
S ++ ++ +P G++I+ + KLYW D RT KIE ID T ++ + S +
Sbjct: 2029 SEKVVLVSMGIAWPNGISIDYEENKLYWCDARTDKIERIDLETGGNREMVLSGSNV 2084
Score = 31.9 bits (69), Expect = 1.9
Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 3/59 (5%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLH---SRQIETIAENCRYPFGLAINGDKLYWSD 422
N ++ID+ +++ + DA I+ IDL +R++ N F +A+ G +YWSD
Sbjct: 2043 NGISIDYEENKLYWCDARTDKIERIDLETGGNREMVLSGSNVDM-FSVAVFGAYIYWSD 2100
Score = 31.5 bits (68), Expect = 2.5
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTK--VRKVLFSVQN-ISNPRGIAVHPQRGKIFWTDWNRSNPKI 189
++WTD + I L V + V++ ++ P G+ V G I+W D N +I
Sbjct: 1302 LYWTDVVEDRIYRGKLSESGGVSAIEVVVEHGLATPEGLTVDWIAGNIYWIDSNLD--QI 1359
Query: 190 EWANMDGTERSVLL 231
E A +DG+ R+ L+
Sbjct: 1360 EVAKLDGSLRTTLI 1373
Score = 31.1 bits (67), Expect = 3.3
Identities = 15/43 (34%), Positives = 25/43 (58%)
Frame = +1
Query: 49 IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRS 177
IE A +D +R++L +N+ P G+AV +I+W D+ S
Sbjct: 4052 IEEAAMDGTLRRILVQ-KNLQRPTGLAVDYFSERIYWADFELS 4093
>AC117947-1|AAX88968.1| 346|Homo sapiens unknown protein.
Length = 346
Score = 77.0 bits (181), Expect = 5e-14
Identities = 42/97 (43%), Positives = 58/97 (59%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW A NI+WTD IEVA L+ R V+ S Q + PR IAVHP++G +FWT+W +
Sbjct: 41 DWIAGNIYWTDHGFNLIEVARLNGSFRYVIIS-QGLDQPRSIAVHPEKGLLFWTEWGQM- 98
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPTLWPSTGREIEF 291
P I A +DG+E+ VL V + WP+ G I++
Sbjct: 99 PCIGKARLDGSEKVVL-----VSMGIAWPN-GISIDY 129
Score = 35.1 bits (77), Expect = 0.21
Identities = 24/80 (30%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Frame = +1
Query: 19 IFWTDSKKLT-IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
+FWT+ ++ I A LD + VL S+ I+ P GI++ + K++W D KIE
Sbjct: 90 LFWTEWGQMPCIGKARLDGSEKVVLVSM-GIAWPNGISIDYEENKLYWCD--ARTDKIER 146
Query: 196 ANMD-GTERSVLLGSPDVKL 252
+++ G R ++L +V +
Sbjct: 147 IDLETGGNREMVLSGSNVDM 166
Score = 32.3 bits (70), Expect = 1.4
Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Frame = +3
Query: 339 SRQIETIAENCRYPFGLAINGD--KLYWSDWRTLKIEIIDTITQARGQIDIPRSTI 500
S ++ ++ +P G++I+ + KLYW D RT KIE ID T ++ + S +
Sbjct: 109 SEKVVLVSMGIAWPNGISIDYEENKLYWCDARTDKIERIDLETGGNREMVLSGSNV 164
Score = 31.9 bits (69), Expect = 1.9
Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 3/59 (5%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLH---SRQIETIAENCRYPFGLAINGDKLYWSD 422
N ++ID+ +++ + DA I+ IDL +R++ N F +A+ G +YWSD
Sbjct: 123 NGISIDYEENKLYWCDARTDKIERIDLETGGNREMVLSGSNVDM-FSVAVFGAYIYWSD 180
Score = 31.5 bits (68), Expect = 2.5
Identities = 22/71 (30%), Positives = 35/71 (49%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
I+WTD I A D ++ + + + GIAV G I+WTD + IE A
Sbjct: 4 IYWTDMGFNKISRAKRDQTWKEDIIT-NGLGRVEGIAVDWIAGNIYWTDHGFN--LIEVA 60
Query: 199 NMDGTERSVLL 231
++G+ R V++
Sbjct: 61 RLNGSFRYVII 71
>AB209683-1|BAD92920.1| 1477|Homo sapiens low density lipoprotein
receptor-related protein 6 variant protein.
Length = 1477
Score = 76.2 bits (179), Expect = 9e-14
Identities = 35/79 (44%), Positives = 52/79 (65%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ARN++WTD+ IEV L+ +RK+L S +++ PR I + P G ++WTDW
Sbjct: 275 DWVARNLYWTDTGTDRIEVTRLNGTMRKILIS-EDLEEPRAIVLDPMVGYMYWTDWGEI- 332
Query: 181 PKIEWANMDGTERSVLLGS 237
PKIE A +DG++R VL+ +
Sbjct: 333 PKIERAALDGSDRVVLVNT 351
Score = 69.7 bits (163), Expect = 8e-12
Identities = 31/77 (40%), Positives = 51/77 (66%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW +N++W D+ IEV+ LD + R+VL +++ +PR +A+ P G ++WT+W
Sbjct: 577 DWLGKNLYWADTGTNRIEVSKLDGQHRQVLV-WKDLDSPRALALDPAEGFMYWTEWG-GK 634
Query: 181 PKIEWANMDGTERSVLL 231
PKI+ A MDG+ER+ L+
Sbjct: 635 PKIDRAAMDGSERTTLV 651
Score = 55.2 bits (127), Expect = 2e-07
Identities = 30/79 (37%), Positives = 44/79 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +R I+WT I V LD + V+ + PR I V+P++G +++T+ +
Sbjct: 886 DIYSRYIYWTCEATNVINVTRLDGRSVGVVLKGEQ-DRPRAIVVNPEKGYMYFTNLQERS 944
Query: 181 PKIEWANMDGTERSVLLGS 237
PKIE A +DGTER VL S
Sbjct: 945 PKIERAALDGTEREVLFFS 963
Score = 48.0 bits (109), Expect = 3e-05
Identities = 20/44 (45%), Positives = 28/44 (63%)
Frame = +1
Query: 106 ISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDGTERSVLLGS 237
+ PR IA+ P G ++WTDW PKIE A MDG+ R +++ S
Sbjct: 1 LDQPRAIALDPSSGFMYWTDWGEV-PKIERAGMDGSSRFIIINS 43
Score = 47.6 bits (108), Expect = 4e-05
Identities = 21/69 (30%), Positives = 37/69 (53%)
Frame = +3
Query: 237 PRCEASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYW 416
P +N + ID+++ R+ + D +I+ ++ E IA++ +PFGL D +YW
Sbjct: 652 PNVGRANGLTIDYAKRRLYWTDLDTNLIESSNMLGLNREVIADDLPHPFGLTQYQDYIYW 711
Query: 417 SDWRTLKIE 443
+DW IE
Sbjct: 712 TDWSRRSIE 720
Score = 44.8 bits (101), Expect = 3e-04
Identities = 29/72 (40%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
Frame = +1
Query: 19 IFWTDSKKLT-IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEW 195
++WTD ++ IE A LD R VL + ++ P G+A+ GKI+W D KIE
Sbjct: 324 MYWTDWGEIPKIERAALDGSDRVVLVNT-SLGWPNGLALDYDEGKIYWGD--AKTDKIEV 380
Query: 196 ANMDGTERSVLL 231
N DGT R VL+
Sbjct: 381 MNTDGTGRRVLV 392
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/88 (30%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D++ R ++WTD IE +N+ R+V+ ++ +P G+ + + I+WTDW+R +
Sbjct: 663 DYAKRRLYWTDLDTNLIESSNMLGLNREVI--ADDLPHPFGLTQY--QDYIYWTDWSRRS 718
Query: 181 PKIEWAN-MDGTERSVLLGSPDVKLPTL 261
IE AN G R+++ G D + L
Sbjct: 719 --IERANKTSGQNRTIIQGHLDYVMDIL 744
Score = 40.7 bits (91), Expect = 0.004
Identities = 25/79 (31%), Positives = 43/79 (54%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
I+WTD + I + +D + + + Q I++P GIAV ++WTD +IE
Sbjct: 238 IYWTDDEVRAIRRSFIDGSGSQFVVTAQ-IAHPDGIAVDWVARNLYWTD--TGTDRIEVT 294
Query: 199 NMDGTERSVLLGSPDVKLP 255
++GT R +L+ S D++ P
Sbjct: 295 RLNGTMRKILI-SEDLEEP 312
Score = 39.9 bits (89), Expect = 0.007
Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAINGDKLYWSDWRT 431
N + +D+ ++ +ADA L I +L + + + + +PF L + D LYW+DW T
Sbjct: 49 NGLTLDYEEQKLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTLFEDILYWTDWST 108
Query: 432 LKI 440
I
Sbjct: 109 HSI 111
Score = 39.1 bits (87), Expect = 0.013
Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 1/83 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D+ I+W D+K IEV N D R+VL I + G + ++WTDW R +
Sbjct: 362 DYDEGKIYWGDAKTDKIEVMNTDGTGRRVLVE-DKIPHIFGFTL--LGDYVYWTDWQRRS 418
Query: 181 PKIEWANMDGTERSVLLGS-PDV 246
IE + ER V++ PD+
Sbjct: 419 --IERVHKRSAEREVIIDQLPDL 439
Score = 38.3 bits (85), Expect = 0.022
Identities = 17/64 (26%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN-CRYPFGLAINGDKLYWSDWRT 431
N +A+D+ ++ + DA I+ ++ + E+ + FG + GD +YW+DW+
Sbjct: 357 NGLALDYDEGKIYWGDAKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTLLGDYVYWTDWQR 416
Query: 432 LKIE 443
IE
Sbjct: 417 RSIE 420
Score = 37.1 bits (82), Expect = 0.051
Identities = 23/60 (38%), Positives = 34/60 (56%)
Frame = +1
Query: 49 IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDGTERSVL 228
IE A LD R+VLF +S P +A+ + GK+FW D + +IE +++ G R VL
Sbjct: 947 IERAALDGTEREVLF-FSGLSKPIALALDSRLGKLFWADSDLR--RIESSDLSGANRIVL 1003
Score = 35.9 bits (79), Expect = 0.12
Identities = 19/68 (27%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
Frame = +3
Query: 252 SNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAE-NCRYPFGLAIN--GDKLYWSD 422
++++ D + +R+ + D L+ I ++ +E + E YP G+A++ G LYW+D
Sbjct: 528 ASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLYWAD 587
Query: 423 WRTLKIEI 446
T +IE+
Sbjct: 588 TGTNRIEV 595
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/57 (29%), Positives = 29/57 (50%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN 171
D+ + ++W D+K I +NLD R+ +V S P A+ ++WTDW+
Sbjct: 54 DYEEQKLYWADAKLNFIHKSNLDGTNRQ---AVVKGSLPHPFALTLFEDILYWTDWS 107
Score = 31.9 bits (69), Expect = 1.9
Identities = 15/41 (36%), Positives = 27/41 (65%), Gaps = 2/41 (4%)
Frame = +3
Query: 339 SRQIETIAENCRYPFGLAINGD--KLYWSDWRTLKIEIIDT 455
S ++ + + +P GLA++ D K+YW D +T KIE+++T
Sbjct: 343 SDRVVLVNTSLGWPNGLALDYDEGKIYWGDAKTDKIEVMNT 383
Score = 31.9 bits (69), Expect = 1.9
Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Frame = +3
Query: 258 SVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
++A+D ++ +AD+ L+ I+ DL + +I N P GL + + LYW D +
Sbjct: 970 ALALDSRLGKLFWADSDLRRIESSDLSGANRIVLEDSNILQPVGLTVFENWLYWIDKQQQ 1029
Query: 435 KIEIID 452
IE ID
Sbjct: 1030 MIEKID 1035
>AB209498-1|BAD92735.1| 2359|Homo sapiens low density
lipoprotein-related protein 1 variant protein.
Length = 2359
Score = 76.2 bits (179), Expect = 9e-14
Identities = 39/86 (45%), Positives = 53/86 (61%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW A N++WTDS + IEVA + + RK L S I P I V P RG ++W+DW ++
Sbjct: 1781 DWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGM-IDEPHAIVVDPLRGTMYWSDWG-NH 1838
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPT 258
PKIE A MDGT R L+ +++ PT
Sbjct: 1839 PKIETAAMDGTLRETLV-QDNIQWPT 1863
Score = 62.5 bits (145), Expect = 1e-09
Identities = 34/90 (37%), Positives = 49/90 (54%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW N++W D + TIEV+ L+ R VL S + PR + V Q G ++WTDW +
Sbjct: 926 DWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVS-SGLREPRALVVDVQNGYLYWTDWG-DH 983
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPTLWPS 270
I MDG+ RSV++ D K+ WP+
Sbjct: 984 SLIGRIGMDGSSRSVIV---DTKI--TWPN 1008
Score = 42.7 bits (96), Expect = 0.001
Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVI-KCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDW 425
N +AID +++ F+DA L I +C S + + +PFGLA+ G+ ++W+DW
Sbjct: 196 NGLAIDHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHPFGLAVYGEHIFWTDW 253
Score = 38.3 bits (85), Expect = 0.022
Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 2/81 (2%)
Frame = +1
Query: 1 DWSARNIFWTD--SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
D+ + I+WTD ++ I +L+ +VL +SNP G+AV G ++W D R
Sbjct: 881 DYREQMIYWTDVTTQGSMIRRMHLNGSNVQVLHRT-GLSNPDGLAVDWVGGNLYWCDKGR 939
Query: 175 SNPKIEWANMDGTERSVLLGS 237
IE + ++G R+VL+ S
Sbjct: 940 DT--IEVSKLNGAYRTVLVSS 958
Score = 37.1 bits (82), Expect = 0.051
Identities = 18/63 (28%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLH-SRQIETIAENCRYPFGLAINGDKLYWSDWRT 431
N + +D+ +R+ +ADA I+ L S + ++++ + F L + D +YW+DW T
Sbjct: 1008 NGLTLDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIPHIFALTLFEDYVYWTDWET 1067
Query: 432 LKI 440
I
Sbjct: 1068 KSI 1070
Score = 36.3 bits (80), Expect = 0.089
Identities = 20/84 (23%), Positives = 37/84 (44%), Gaps = 5/84 (5%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTK-----VRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNP 183
++WT TI +D R+ + ++ +PR + + +FWT+WN +P
Sbjct: 113 LYWTSYTTSTITRHTVDQTRPGAFERETVITMSGDDHPRAFVLDECQNLMFWTNWNEQHP 172
Query: 184 KIEWANMDGTERSVLLGSPDVKLP 255
I A + G L+ D++ P
Sbjct: 173 SIMRAALSGANVLTLI-EKDIRTP 195
Score = 34.7 bits (76), Expect = 0.27
Identities = 17/46 (36%), Positives = 24/46 (52%)
Frame = +1
Query: 94 SVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDGTERSVLL 231
++ + PRGIA+ G ++WTD R IE A M G R L+
Sbjct: 1768 NISGLKMPRGIAIDWVAGNVYWTDSGRD--VIEVAQMKGENRKTLI 1811
Score = 33.5 bits (73), Expect = 0.63
Identities = 19/58 (32%), Positives = 31/58 (53%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
D A ++++D+ IE D R V+ + + +P G+AV+ + IFWTDW R
Sbjct: 201 DHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPV-HPFGLAVYGEH--IFWTDWVR 255
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIET-IAENCRYPFGLAIN--GDKLYWSDW 425
+AIDW V + D+G VI+ + +T I+ P + ++ +YWSDW
Sbjct: 1778 IAIDWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDW 1835
Score = 31.1 bits (67), Expect = 3.3
Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Frame = +1
Query: 19 IFWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTD 165
++W+D IE A +D +R+ L NI P G+AV +++W D
Sbjct: 1830 MYWSDWGNHPKIETAAMDGTLRETLVQ-DNIQWPTGLAVDYHNERLYWAD 1878
>Z75190-1|CAA99509.1| 699|Homo sapiens apolipoprotein E receptor 2
906 protein.
Length = 699
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/85 (43%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++I+WTDS TI VA +D R+ LFS +N+S PR IAV P RG ++W+DW
Sbjct: 375 DWVHKHIYWTDSGNKTISVATVDGGRRRTLFS-RNLSEPRAIAVDPLRGFMYWSDWG-DQ 432
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE + ++G +R L+ S +++ P
Sbjct: 433 AKIEKSGLNGVDRQTLV-SDNIEWP 456
Score = 35.9 bits (79), Expect = 0.12
Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRY---PFGLAINGDKLYW 416
E N + +D R+ + D+ L + ID +T+ + + PFG+A+ DK++W
Sbjct: 454 EWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFW 513
Query: 417 SD 422
+D
Sbjct: 514 TD 515
Score = 34.7 bits (76), Expect = 0.27
Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Frame = +1
Query: 7 SARNIFWTDSKKLTIEVANLDT----KVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
+ I+W D I A +D K R+VL Q + +P G+AV I+WTD
Sbjct: 330 ATNRIYWCDLSYRKIYSAYMDKASDPKEREVLIDEQ-LHSPEGLAVDWVHKHIYWTD--S 386
Query: 175 SNPKIEWANMDGTERSVL 228
N I A +DG R L
Sbjct: 387 GNKTISVATVDGGRRRTL 404
Score = 31.9 bits (69), Expect = 1.9
Identities = 15/58 (25%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAINGDK--LYWSDW 425
+A+DW + + D+G + I + + T+ + N P +A++ + +YWSDW
Sbjct: 372 LAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDW 429
>D86407-2|BAA21825.1| 793|Homo sapiens ApoER2delta4-7 protein.
Length = 793
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/85 (43%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++I+WTDS TI VA +D R+ LFS +N+S PR IAV P RG ++W+DW
Sbjct: 335 DWVHKHIYWTDSGNKTISVATVDGGRRRTLFS-RNLSEPRAIAVDPLRGFMYWSDWG-DQ 392
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE + ++G +R L+ S +++ P
Sbjct: 393 AKIEKSGLNGVDRQTLV-SDNIEWP 416
Score = 35.9 bits (79), Expect = 0.12
Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRY---PFGLAINGDKLYW 416
E N + +D R+ + D+ L + ID +T+ + + PFG+A+ DK++W
Sbjct: 414 EWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFW 473
Query: 417 SD 422
+D
Sbjct: 474 TD 475
Score = 33.1 bits (72), Expect = 0.83
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Frame = +1
Query: 7 SARNIFWTDSKKLTIEVANLDT----KVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
+ I+W D I A +D K ++VL Q + +P G+AV I+WTD
Sbjct: 290 ATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQ-LHSPEGLAVDWVHKHIYWTD--S 346
Query: 175 SNPKIEWANMDGTERSVL 228
N I A +DG R L
Sbjct: 347 GNKTISVATVDGGRRRTL 364
Score = 31.9 bits (69), Expect = 1.9
Identities = 15/58 (25%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAINGDK--LYWSDW 425
+A+DW + + D+G + I + + T+ + N P +A++ + +YWSDW
Sbjct: 332 LAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDW 389
>D86407-1|BAA21824.1| 963|Homo sapiens ApoER2 protein.
Length = 963
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/85 (43%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++I+WTDS TI VA +D R+ LFS +N+S PR IAV P RG ++W+DW
Sbjct: 505 DWVHKHIYWTDSGNKTISVATVDGGRRRTLFS-RNLSEPRAIAVDPLRGFMYWSDWG-DQ 562
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE + ++G +R L+ S +++ P
Sbjct: 563 AKIEKSGLNGVDRQTLV-SDNIEWP 586
Score = 35.9 bits (79), Expect = 0.12
Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRY---PFGLAINGDKLYW 416
E N + +D R+ + D+ L + ID +T+ + + PFG+A+ DK++W
Sbjct: 584 EWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFW 643
Query: 417 SD 422
+D
Sbjct: 644 TD 645
Score = 33.1 bits (72), Expect = 0.83
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Frame = +1
Query: 7 SARNIFWTDSKKLTIEVANLDT----KVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
+ I+W D I A +D K ++VL Q + +P G+AV I+WTD
Sbjct: 460 ATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQ-LHSPEGLAVDWVHKHIYWTD--S 516
Query: 175 SNPKIEWANMDGTERSVL 228
N I A +DG R L
Sbjct: 517 GNKTISVATVDGGRRRTL 534
Score = 31.9 bits (69), Expect = 1.9
Identities = 15/58 (25%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAINGDK--LYWSDW 425
+A+DW + + D+G + I + + T+ + N P +A++ + +YWSDW
Sbjct: 502 LAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDW 559
>D50678-1|BAA09328.1| 963|Homo sapiens apolipoprotein E receptor 2
precursor protein.
Length = 963
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/85 (43%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++I+WTDS TI VA +D R+ LFS +N+S PR IAV P RG ++W+DW
Sbjct: 505 DWVHKHIYWTDSGNKTISVATVDGGRRRTLFS-RNLSEPRAIAVDPLRGFMYWSDWG-DQ 562
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE + ++G +R L+ S +++ P
Sbjct: 563 AKIEKSGLNGVDRQTLV-SDNIEWP 586
Score = 35.9 bits (79), Expect = 0.12
Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRY---PFGLAINGDKLYW 416
E N + +D R+ + D+ L + ID +T+ + + PFG+A+ DK++W
Sbjct: 584 EWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFW 643
Query: 417 SD 422
+D
Sbjct: 644 TD 645
Score = 33.1 bits (72), Expect = 0.83
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Frame = +1
Query: 7 SARNIFWTDSKKLTIEVANLDT----KVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
+ I+W D I A +D K ++VL Q + +P G+AV I+WTD
Sbjct: 460 ATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQ-LHSPEGLAVDWVHKHIYWTD--S 516
Query: 175 SNPKIEWANMDGTERSVL 228
N I A +DG R L
Sbjct: 517 GNKTISVATVDGGRRRTL 534
Score = 31.9 bits (69), Expect = 1.9
Identities = 15/58 (25%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAINGDK--LYWSDW 425
+A+DW + + D+G + I + + T+ + N P +A++ + +YWSDW
Sbjct: 502 LAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDW 559
>BC051836-1|AAH51836.2| 904|Homo sapiens low density lipoprotein
receptor-related protein 8, apolipoprotein e receptor
protein.
Length = 904
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/85 (43%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++I+WTDS TI VA +D R+ LFS +N+S PR IAV P RG ++W+DW
Sbjct: 505 DWVHKHIYWTDSGNKTISVATVDGGRRRTLFS-RNLSEPRAIAVDPLRGFMYWSDWG-DQ 562
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE + ++G +R L+ S +++ P
Sbjct: 563 AKIEKSGLNGVDRQTLV-SDNIEWP 586
Score = 35.9 bits (79), Expect = 0.12
Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRY---PFGLAINGDKLYW 416
E N + +D R+ + D+ L + ID +T+ + + PFG+A+ DK++W
Sbjct: 584 EWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFW 643
Query: 417 SD 422
+D
Sbjct: 644 TD 645
Score = 33.1 bits (72), Expect = 0.83
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Frame = +1
Query: 7 SARNIFWTDSKKLTIEVANLDT----KVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
+ I+W D I A +D K ++VL Q + +P G+AV I+WTD
Sbjct: 460 ATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQ-LHSPEGLAVDWVHKHIYWTD--S 516
Query: 175 SNPKIEWANMDGTERSVL 228
N I A +DG R L
Sbjct: 517 GNKTISVATVDGGRRRTL 534
Score = 31.9 bits (69), Expect = 1.9
Identities = 15/58 (25%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAINGDK--LYWSDW 425
+A+DW + + D+G + I + + T+ + N P +A++ + +YWSDW
Sbjct: 502 LAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDW 559
>AL606760-4|CAI18908.1| 963|Homo sapiens low density lipoprotein
receptor-related protein 8, apolipoprotein e receptor
protein.
Length = 963
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/85 (43%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++I+WTDS TI VA +D R+ LFS +N+S PR IAV P RG ++W+DW
Sbjct: 505 DWVHKHIYWTDSGNKTISVATVDGGRRRTLFS-RNLSEPRAIAVDPLRGFMYWSDWG-DQ 562
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE + ++G +R L+ S +++ P
Sbjct: 563 AKIEKSGLNGVDRQTLV-SDNIEWP 586
Score = 35.9 bits (79), Expect = 0.12
Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRY---PFGLAINGDKLYW 416
E N + +D R+ + D+ L + ID +T+ + + PFG+A+ DK++W
Sbjct: 584 EWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFW 643
Query: 417 SD 422
+D
Sbjct: 644 TD 645
Score = 33.1 bits (72), Expect = 0.83
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Frame = +1
Query: 7 SARNIFWTDSKKLTIEVANLDT----KVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
+ I+W D I A +D K ++VL Q + +P G+AV I+WTD
Sbjct: 460 ATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQ-LHSPEGLAVDWVHKHIYWTD--S 516
Query: 175 SNPKIEWANMDGTERSVL 228
N I A +DG R L
Sbjct: 517 GNKTISVATVDGGRRRTL 534
Score = 31.9 bits (69), Expect = 1.9
Identities = 15/58 (25%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAINGDK--LYWSDW 425
+A+DW + + D+G + I + + T+ + N P +A++ + +YWSDW
Sbjct: 502 LAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDW 559
>AL606760-3|CAI18909.1| 700|Homo sapiens low density lipoprotein
receptor-related protein 8, apolipoprotein e receptor
protein.
Length = 700
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/85 (43%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++I+WTDS TI VA +D R+ LFS +N+S PR IAV P RG ++W+DW
Sbjct: 376 DWVHKHIYWTDSGNKTISVATVDGGRRRTLFS-RNLSEPRAIAVDPLRGFMYWSDWG-DQ 433
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE + ++G +R L+ S +++ P
Sbjct: 434 AKIEKSGLNGVDRQTLV-SDNIEWP 457
Score = 35.9 bits (79), Expect = 0.12
Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRY---PFGLAINGDKLYW 416
E N + +D R+ + D+ L + ID +T+ + + PFG+A+ DK++W
Sbjct: 455 EWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFW 514
Query: 417 SD 422
+D
Sbjct: 515 TD 516
Score = 33.1 bits (72), Expect = 0.83
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Frame = +1
Query: 7 SARNIFWTDSKKLTIEVANLDT----KVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
+ I+W D I A +D K ++VL Q + +P G+AV I+WTD
Sbjct: 331 ATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQ-LHSPEGLAVDWVHKHIYWTD--S 387
Query: 175 SNPKIEWANMDGTERSVL 228
N I A +DG R L
Sbjct: 388 GNKTISVATVDGGRRRTL 405
Score = 31.9 bits (69), Expect = 1.9
Identities = 15/58 (25%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAINGDK--LYWSDW 425
+A+DW + + D+G + I + + T+ + N P +A++ + +YWSDW
Sbjct: 373 LAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDW 430
>AL606760-2|CAI18910.1| 904|Homo sapiens low density lipoprotein
receptor-related protein 8, apolipoprotein e receptor
protein.
Length = 904
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/85 (43%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++I+WTDS TI VA +D R+ LFS +N+S PR IAV P RG ++W+DW
Sbjct: 505 DWVHKHIYWTDSGNKTISVATVDGGRRRTLFS-RNLSEPRAIAVDPLRGFMYWSDWG-DQ 562
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE + ++G +R L+ S +++ P
Sbjct: 563 AKIEKSGLNGVDRQTLV-SDNIEWP 586
Score = 35.9 bits (79), Expect = 0.12
Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRY---PFGLAINGDKLYW 416
E N + +D R+ + D+ L + ID +T+ + + PFG+A+ DK++W
Sbjct: 584 EWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFW 643
Query: 417 SD 422
+D
Sbjct: 644 TD 645
Score = 33.1 bits (72), Expect = 0.83
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Frame = +1
Query: 7 SARNIFWTDSKKLTIEVANLDT----KVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
+ I+W D I A +D K ++VL Q + +P G+AV I+WTD
Sbjct: 460 ATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQ-LHSPEGLAVDWVHKHIYWTD--S 516
Query: 175 SNPKIEWANMDGTERSVL 228
N I A +DG R L
Sbjct: 517 GNKTISVATVDGGRRRTL 534
Score = 31.9 bits (69), Expect = 1.9
Identities = 15/58 (25%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAINGDK--LYWSDW 425
+A+DW + + D+G + I + + T+ + N P +A++ + +YWSDW
Sbjct: 502 LAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDW 559
>AL355483-3|CAI22781.1| 963|Homo sapiens low density lipoprotein
receptor-related protein 8, apolipoprotein e receptor
protein.
Length = 963
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/85 (43%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++I+WTDS TI VA +D R+ LFS +N+S PR IAV P RG ++W+DW
Sbjct: 505 DWVHKHIYWTDSGNKTISVATVDGGRRRTLFS-RNLSEPRAIAVDPLRGFMYWSDWG-DQ 562
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE + ++G +R L+ S +++ P
Sbjct: 563 AKIEKSGLNGVDRQTLV-SDNIEWP 586
Score = 35.9 bits (79), Expect = 0.12
Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRY---PFGLAINGDKLYW 416
E N + +D R+ + D+ L + ID +T+ + + PFG+A+ DK++W
Sbjct: 584 EWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFW 643
Query: 417 SD 422
+D
Sbjct: 644 TD 645
Score = 33.1 bits (72), Expect = 0.83
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Frame = +1
Query: 7 SARNIFWTDSKKLTIEVANLDT----KVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
+ I+W D I A +D K ++VL Q + +P G+AV I+WTD
Sbjct: 460 ATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQ-LHSPEGLAVDWVHKHIYWTD--S 516
Query: 175 SNPKIEWANMDGTERSVL 228
N I A +DG R L
Sbjct: 517 GNKTISVATVDGGRRRTL 534
Score = 31.9 bits (69), Expect = 1.9
Identities = 15/58 (25%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAINGDK--LYWSDW 425
+A+DW + + D+G + I + + T+ + N P +A++ + +YWSDW
Sbjct: 502 LAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDW 559
>AL355483-2|CAI22782.1| 700|Homo sapiens low density lipoprotein
receptor-related protein 8, apolipoprotein e receptor
protein.
Length = 700
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/85 (43%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++I+WTDS TI VA +D R+ LFS +N+S PR IAV P RG ++W+DW
Sbjct: 376 DWVHKHIYWTDSGNKTISVATVDGGRRRTLFS-RNLSEPRAIAVDPLRGFMYWSDWG-DQ 433
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE + ++G +R L+ S +++ P
Sbjct: 434 AKIEKSGLNGVDRQTLV-SDNIEWP 457
Score = 35.9 bits (79), Expect = 0.12
Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRY---PFGLAINGDKLYW 416
E N + +D R+ + D+ L + ID +T+ + + PFG+A+ DK++W
Sbjct: 455 EWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFW 514
Query: 417 SD 422
+D
Sbjct: 515 TD 516
Score = 33.1 bits (72), Expect = 0.83
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Frame = +1
Query: 7 SARNIFWTDSKKLTIEVANLDT----KVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
+ I+W D I A +D K ++VL Q + +P G+AV I+WTD
Sbjct: 331 ATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQ-LHSPEGLAVDWVHKHIYWTD--S 387
Query: 175 SNPKIEWANMDGTERSVL 228
N I A +DG R L
Sbjct: 388 GNKTISVATVDGGRRRTL 405
Score = 31.9 bits (69), Expect = 1.9
Identities = 15/58 (25%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAINGDK--LYWSDW 425
+A+DW + + D+G + I + + T+ + N P +A++ + +YWSDW
Sbjct: 373 LAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDW 430
>AL355483-1|CAI22780.1| 904|Homo sapiens low density lipoprotein
receptor-related protein 8, apolipoprotein e receptor
protein.
Length = 904
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/85 (43%), Positives = 55/85 (64%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW ++I+WTDS TI VA +D R+ LFS +N+S PR IAV P RG ++W+DW
Sbjct: 505 DWVHKHIYWTDSGNKTISVATVDGGRRRTLFS-RNLSEPRAIAVDPLRGFMYWSDWG-DQ 562
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE + ++G +R L+ S +++ P
Sbjct: 563 AKIEKSGLNGVDRQTLV-SDNIEWP 586
Score = 35.9 bits (79), Expect = 0.12
Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRY---PFGLAINGDKLYW 416
E N + +D R+ + D+ L + ID +T+ + + PFG+A+ DK++W
Sbjct: 584 EWPNGITLDLLSQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFW 643
Query: 417 SD 422
+D
Sbjct: 644 TD 645
Score = 33.1 bits (72), Expect = 0.83
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Frame = +1
Query: 7 SARNIFWTDSKKLTIEVANLDT----KVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
+ I+W D I A +D K ++VL Q + +P G+AV I+WTD
Sbjct: 460 ATNRIYWCDLSYRKIYSAYMDKASDPKEQEVLIDEQ-LHSPEGLAVDWVHKHIYWTD--S 516
Query: 175 SNPKIEWANMDGTERSVL 228
N I A +DG R L
Sbjct: 517 GNKTISVATVDGGRRRTL 534
Score = 31.9 bits (69), Expect = 1.9
Identities = 15/58 (25%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAINGDK--LYWSDW 425
+A+DW + + D+G + I + + T+ + N P +A++ + +YWSDW
Sbjct: 502 LAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDW 559
>U04441-1|AAB02882.1| 1751|Homo sapiens glycoprotein 330 protein.
Length = 1751
Score = 74.9 bits (176), Expect = 2e-13
Identities = 38/86 (44%), Positives = 55/86 (63%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW R+I+W+D K IEVA LD + RK L S ++ P IAV+P+ G +FWTDW +
Sbjct: 1448 DWVGRHIYWSDVKNKRIEVAKLDGRYRKWLIST-DLDQPAAIAVNPKLGLMFWTDWGK-E 1505
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPT 258
PK+E A M+G + ++L+ D+ PT
Sbjct: 1506 PKLESAWMNGEDPNILV-FEDLGWPT 1530
Score = 57.6 bits (133), Expect = 3e-08
Identities = 29/86 (33%), Positives = 48/86 (55%), Gaps = 7/86 (8%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVL----FSVQN---ISNPRGIAVHPQRGKIFW 159
DW +R ++W D++ + V++L+ R++L N NPRG+A+HPQ G ++W
Sbjct: 575 DWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYW 634
Query: 160 TDWNRSNPKIEWANMDGTERSVLLGS 237
DW I MDGT +SV++ +
Sbjct: 635 ADWGH-RAYIGRVGMDGTNKSVIIST 659
Score = 49.6 bits (113), Expect = 9e-06
Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +3
Query: 240 RCEASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCR-YPFGLAINGDKLYW 416
+ E N + ID++ D + +ADA L I+ DL T+ + +PF + I D +YW
Sbjct: 660 KLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDGALPHPFAITIFEDTIYW 719
Query: 417 SDWRTLKIE 443
+DW T +E
Sbjct: 720 TDWNTRTVE 728
Score = 33.9 bits (74), Expect = 0.47
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 11/73 (15%)
Frame = +3
Query: 240 RCEASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENC---------RYPFGLA 392
R A+ S+A+DW ++ + DA L + DL+ +A++C P GLA
Sbjct: 565 RLPAAESLAVDWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLA 624
Query: 393 INGD--KLYWSDW 425
++ LYW+DW
Sbjct: 625 LHPQYGYLYWADW 637
Score = 32.3 bits (70), Expect = 1.4
Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D++ ++W D+ IE ++L+ R ++ + +P I + I+WTDWN
Sbjct: 670 DYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDGA-LPHPFAITIFEDT--IYWTDWNTRT 726
Query: 181 PKIEWAN-MDGTERSVLLGS 237
+E N DG+ R L+ +
Sbjct: 727 --VEKGNKYDGSNRQTLVNT 744
Score = 31.1 bits (67), Expect = 3.3
Identities = 21/60 (35%), Positives = 32/60 (53%)
Frame = +1
Query: 76 VRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWANMDGTERSVLLGSPDVKLP 255
V++V ++ + P GIAV I+W+D N +IE A +DG R L+ S D+ P
Sbjct: 1429 VQEVDLKLKYVMQPDGIAVDWVGRHIYWSD--VKNKRIEVAKLDGRYRKWLI-STDLDQP 1485
>AK054663-1|BAB70786.1| 820|Homo sapiens umor (LRPDIT) mRNA.
protein.
Length = 820
Score = 72.9 bits (171), Expect = 8e-13
Identities = 38/90 (42%), Positives = 53/90 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW A NI+W DS IEVA LD +R L + + +PR IA+ P+ G +FWTDW+ +
Sbjct: 526 DWIAGNIYWIDSNLDQIEVAKLDGSLRTTLIAGA-MEHPRAIALDPRYGILFWTDWDANF 584
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPTLWPS 270
P+IE A+M G R + D+K WP+
Sbjct: 585 PRIESASMSGAGRKTIY--KDMKTGA-WPN 611
Score = 37.1 bits (82), Expect = 0.051
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVI-KCIDLHSRQIETIA--ENCRYPFGLAINGDKLYWSDW 425
N + +D R+ + DA I + + IE I E +PF +++ G ++YW+DW
Sbjct: 611 NGLTVDHFEKRIVWTDARSDAIYSALYDGTNMIEIIRGHEYLSHPFAVSLYGSEVYWTDW 670
Query: 426 RT 431
RT
Sbjct: 671 RT 672
Score = 32.3 bits (70), Expect = 1.4
Identities = 20/77 (25%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLD-TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRS 177
D + I WTD++ I A D T + +++ + +S+P ++++ +++WTDW R+
Sbjct: 616 DHFEKRIVWTDARSDAIYSALYDGTNMIEIIRGHEYLSHPFAVSLYGS--EVYWTDW-RT 672
Query: 178 NPKIEWANMDGTERSVL 228
N + G SV+
Sbjct: 673 NTLSKANKWTGQNVSVI 689
Score = 31.5 bits (68), Expect = 2.5
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTK--VRKVLFSVQN-ISNPRGIAVHPQRGKIFWTDWNRSNPKI 189
++WTD + I L V + V++ ++ P G+ V G I+W D N +I
Sbjct: 485 LYWTDVVEDRIYRGKLSESGGVSAIEVVVEHGLATPEGLTVDWIAGNIYWIDSNLD--QI 542
Query: 190 EWANMDGTERSVLL 231
E A +DG+ R+ L+
Sbjct: 543 EVAKLDGSLRTTLI 556
>AC010740-1|AAY14689.1| 862|Homo sapiens unknown protein.
Length = 862
Score = 72.9 bits (171), Expect = 8e-13
Identities = 38/90 (42%), Positives = 53/90 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW A NI+W DS IEVA LD +R L + + +PR IA+ P+ G +FWTDW+ +
Sbjct: 419 DWIAGNIYWIDSNLDQIEVAKLDGSLRTTLIAGA-MEHPRAIALDPRYGILFWTDWDANF 477
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPTLWPS 270
P+IE A+M G R + D+K WP+
Sbjct: 478 PRIESASMSGAGRKTIY--KDMKTGA-WPN 504
Score = 60.1 bits (139), Expect = 6e-09
Identities = 30/78 (38%), Positives = 45/78 (57%), Gaps = 2/78 (2%)
Frame = +1
Query: 1 DWSARNIFWTDSK--KLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
DW +RN++W S+ + I VA LD ++ + + I P+ +A HP RGK++WTD N
Sbjct: 733 DWVSRNLYWISSEFDETQINVARLDGSLKTSI--IHGIDKPQCLAAHPVRGKLYWTDGN- 789
Query: 175 SNPKIEWANMDGTERSVL 228
I ANMDG+ +L
Sbjct: 790 ---TINMANMDGSNSKIL 804
Score = 41.1 bits (92), Expect = 0.003
Identities = 23/70 (32%), Positives = 36/70 (51%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
++WTD TI +AN+D K+LF QN P G+++ K++W + N I
Sbjct: 783 LYWTDGN--TINMANMDGSNSKILF--QNQKEPVGLSIDYVENKLYWI--SSGNGTINRC 836
Query: 199 NMDGTERSVL 228
N+DG V+
Sbjct: 837 NLDGGNLEVI 846
Score = 37.1 bits (82), Expect = 0.051
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVI-KCIDLHSRQIETIA--ENCRYPFGLAINGDKLYWSDW 425
N + +D R+ + DA I + + IE I E +PF +++ G ++YW+DW
Sbjct: 504 NGLTVDHFEKRIVWTDARSDAIYSALYDGTNMIEIIRGHEYLSHPFAVSLYGSEVYWTDW 563
Query: 426 RT 431
RT
Sbjct: 564 RT 565
Score = 35.5 bits (78), Expect = 0.16
Identities = 21/81 (25%), Positives = 41/81 (50%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D S ++WTD K TI+ A ++ + + S ++I + RG+AV ++W
Sbjct: 690 DASEERLYWTDIKTQTIKRAFINGTGLETVIS-RDIQSIRGLAVDWVSRNLYWISSEFDE 748
Query: 181 PKIEWANMDGTERSVLLGSPD 243
+I A +DG+ ++ ++ D
Sbjct: 749 TQINVARLDGSLKTSIIHGID 769
Score = 32.3 bits (70), Expect = 1.4
Identities = 20/77 (25%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLD-TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRS 177
D + I WTD++ I A D T + +++ + +S+P ++++ +++WTDW R+
Sbjct: 509 DHFEKRIVWTDARSDAIYSALYDGTNMIEIIRGHEYLSHPFAVSLYGS--EVYWTDW-RT 565
Query: 178 NPKIEWANMDGTERSVL 228
N + G SV+
Sbjct: 566 NTLSKANKWTGQNVSVI 582
Score = 31.5 bits (68), Expect = 2.5
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTK--VRKVLFSVQN-ISNPRGIAVHPQRGKIFWTDWNRSNPKI 189
++WTD + I L V + V++ ++ P G+ V G I+W D N +I
Sbjct: 378 LYWTDVVEDRIYRGKLSESGGVSAIEVVVEHGLATPEGLTVDWIAGNIYWIDSNLD--QI 435
Query: 190 EWANMDGTERSVLL 231
E A +DG+ R+ L+
Sbjct: 436 EVAKLDGSLRTTLI 449
>X04571-1|CAA28240.1| 1207|Homo sapiens protein ( Human mRNA for
kidney epidermal growth factor (EGF) precursor. ).
Length = 1207
Score = 71.7 bits (168), Expect = 2e-12
Identities = 40/97 (41%), Positives = 57/97 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW R +WTD K I ++L+ K K++ + +NIS PRGIAVHP ++FWTD N
Sbjct: 563 DWIGRRFYWTDRGKSLIGRSDLNGKRSKII-TKENISQPRGIAVHPMAKRLFWTD-TGIN 620
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPTLWPSTGREIEF 291
P+IE +++ G R V+ S +WPS G I+F
Sbjct: 621 PRIESSSLQGLGRLVIASS-----DLIWPS-GITIDF 651
Score = 35.9 bits (79), Expect = 0.12
Identities = 24/80 (30%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D+ ++W D+K+ IE+ANLD R+ L + ++ +P +AV ++++DW +
Sbjct: 650 DFLTDKLYWCDAKQSVIEMANLDGSKRRRL-TQNDVGHPFAVAVF--EDYVWFSDW--AM 704
Query: 181 PKIEWAN-MDGTERSVLLGS 237
P + N G +R L GS
Sbjct: 705 PSVIRVNKRTGKDRVRLQGS 724
Score = 34.7 bits (76), Expect = 0.27
Identities = 16/58 (27%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN-CRYPFGLAINGDKLYWSDW 425
+ + ID+ D++ + DA VI+ +L + + +N +PF +A+ D +++SDW
Sbjct: 645 SGITIDFLTDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDW 702
>BC113461-1|AAI13462.1| 1207|Homo sapiens epidermal growth factor
(beta-urogastrone) protein.
Length = 1207
Score = 71.7 bits (168), Expect = 2e-12
Identities = 40/97 (41%), Positives = 57/97 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW R +WTD K I ++L+ K K++ + +NIS PRGIAVHP ++FWTD N
Sbjct: 563 DWIGRRFYWTDRGKSLIGRSDLNGKRSKII-TKENISQPRGIAVHPMAKRLFWTD-TGIN 620
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPTLWPSTGREIEF 291
P+IE +++ G R V+ S +WPS G I+F
Sbjct: 621 PRIESSSLQGLGRLVIASS-----DLIWPS-GITIDF 651
Score = 35.9 bits (79), Expect = 0.12
Identities = 24/80 (30%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D+ ++W D+K+ IE+ANLD R+ L + ++ +P +AV ++++DW +
Sbjct: 650 DFLTDKLYWCDAKQSVIEMANLDGSKRRRL-TQNDVGHPFAVAVF--EDYVWFSDW--AM 704
Query: 181 PKIEWAN-MDGTERSVLLGS 237
P + N G +R L GS
Sbjct: 705 PSVIRVNKRTGKDRVRLQGS 724
Score = 34.7 bits (76), Expect = 0.27
Identities = 16/58 (27%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN-CRYPFGLAINGDKLYWSDW 425
+ + ID+ D++ + DA VI+ +L + + +N +PF +A+ D +++SDW
Sbjct: 645 SGITIDFLTDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDW 702
>BC093731-1|AAH93731.1| 1207|Homo sapiens epidermal growth factor
(beta-urogastrone) protein.
Length = 1207
Score = 71.7 bits (168), Expect = 2e-12
Identities = 40/97 (41%), Positives = 57/97 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW R +WTD K I ++L+ K K++ + +NIS PRGIAVHP ++FWTD N
Sbjct: 563 DWIGRRFYWTDRGKSLIGRSDLNGKRSKII-TKENISQPRGIAVHPMAKRLFWTD-TGIN 620
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPTLWPSTGREIEF 291
P+IE +++ G R V+ S +WPS G I+F
Sbjct: 621 PRIESSSLQGLGRLVIASS-----DLIWPS-GITIDF 651
Score = 35.9 bits (79), Expect = 0.12
Identities = 24/80 (30%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D+ ++W D+K+ IE+ANLD R+ L + ++ +P +AV ++++DW +
Sbjct: 650 DFLTDKLYWCDAKQSVIEMANLDGSKRRRL-TQNDVGHPFAVAVF--EDYVWFSDW--AM 704
Query: 181 PKIEWAN-MDGTERSVLLGS 237
P + N G +R L GS
Sbjct: 705 PSVIRVNKRTGKDRVRLQGS 724
Score = 34.7 bits (76), Expect = 0.27
Identities = 16/58 (27%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN-CRYPFGLAINGDKLYWSDW 425
+ + ID+ D++ + DA VI+ +L + + +N +PF +A+ D +++SDW
Sbjct: 645 SGITIDFLTDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDW 702
>AY506357-1|AAR84237.1| 1152|Homo sapiens truncated epidermal growth
factor (beta-urogastrone) protein.
Length = 1152
Score = 71.7 bits (168), Expect = 2e-12
Identities = 40/97 (41%), Positives = 57/97 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW R +WTD K I ++L+ K K++ + +NIS PRGIAVHP ++FWTD N
Sbjct: 563 DWIGRRFYWTDRGKSLIGRSDLNGKRSKII-TKENISQPRGIAVHPMAKRLFWTD-TGIN 620
Query: 181 PKIEWANMDGTERSVLLGSPDVKLPTLWPSTGREIEF 291
P+IE +++ G R V+ S +WPS G I+F
Sbjct: 621 PRIESSSLQGLGRLVIASS-----DLIWPS-GITIDF 651
Score = 35.9 bits (79), Expect = 0.12
Identities = 24/80 (30%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D+ ++W D+K+ IE+ANLD R+ L + ++ +P +AV ++++DW +
Sbjct: 650 DFLTDKLYWCDAKQSVIEMANLDGSKRRRL-TQNDVGHPFAVAVF--EDYVWFSDW--AM 704
Query: 181 PKIEWAN-MDGTERSVLLGS 237
P + N G +R L GS
Sbjct: 705 PSVIRVNKRTGKDRVRLQGS 724
Score = 34.7 bits (76), Expect = 0.27
Identities = 16/58 (27%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN-CRYPFGLAINGDKLYWSDW 425
+ + ID+ D++ + DA VI+ +L + + +N +PF +A+ D +++SDW
Sbjct: 645 SGITIDFLTDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDW 702
>S73849-1|AAB31735.1| 873|Homo sapiens very low density lipoprotein
receptor protein.
Length = 873
Score = 68.1 bits (159), Expect = 2e-11
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW + I+WTD+ TI VA LD RK LF+ ++ P IAV P G ++W+DW
Sbjct: 521 DWVYKTIYWTDAASKTISVATLDGTKRKFLFN-SDLREPASIAVDPLSGFVYWSDWGEP- 578
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE A M+G +R L+ + D++ P
Sbjct: 579 AKIEKAGMNGFDRRPLV-TADIQWP 602
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/85 (35%), Positives = 47/85 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +A+ +FW D + I A++D KV + + + N+ NP IAV I+WTD ++
Sbjct: 477 DIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYNPAAIAVDWVYKTIYWTD--AAS 534
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
I A +DGT+R L S D++ P
Sbjct: 535 KTISVATLDGTKRKFLFNS-DLREP 558
>L22431-1|AAA61344.1| 873|Homo sapiens very low density lipoprotein
receptor protein.
Length = 873
Score = 68.1 bits (159), Expect = 2e-11
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW + I+WTD+ TI VA LD RK LF+ ++ P IAV P G ++W+DW
Sbjct: 521 DWVYKTIYWTDAASKTISVATLDGTKRKFLFN-SDLREPASIAVDPLSGFVYWSDWGEP- 578
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE A M+G +R L+ + D++ P
Sbjct: 579 AKIEKAGMNGFDRRPLV-TADIQWP 602
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/85 (35%), Positives = 47/85 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +A+ +FW D + I A++D KV + + + N+ NP IAV I+WTD ++
Sbjct: 477 DIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYNPAAIAVDWVYKTIYWTD--AAS 534
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
I A +DGT+R L S D++ P
Sbjct: 535 KTISVATLDGTKRKFLFNS-DLREP 558
>L20470-1|AAA53684.1| 873|Homo sapiens very low density lipoprotein
receptor protein.
Length = 873
Score = 68.1 bits (159), Expect = 2e-11
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW + I+WTD+ TI VA LD RK LF+ ++ P IAV P G ++W+DW
Sbjct: 521 DWVYKTIYWTDAASKTISVATLDGTKRKFLFN-SDLREPASIAVDPLSGFVYWSDWGEP- 578
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE A M+G +R L+ + D++ P
Sbjct: 579 AKIEKAGMNGFDRRPLV-TADIQWP 602
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/85 (35%), Positives = 47/85 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +A+ +FW D + I A++D KV + + + N+ NP IAV I+WTD ++
Sbjct: 477 DIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYNPAAIAVDWVYKTIYWTD--AAS 534
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
I A +DGT+R L S D++ P
Sbjct: 535 KTISVATLDGTKRKFLFNS-DLREP 558
>D16532-1|BAA03969.1| 873|Homo sapiens very low density lipoprotein
receptor protein.
Length = 873
Score = 68.1 bits (159), Expect = 2e-11
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW + I+WTD+ TI VA LD RK LF+ ++ P IAV P G ++W+DW
Sbjct: 521 DWVYKTIYWTDAASKTISVATLDGTKRKFLFN-SDLREPASIAVDPLSGFVYWSDWGEP- 578
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE A M+G +R L+ + D++ P
Sbjct: 579 AKIEKAGMNGFDRRPLV-TADIQWP 602
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/85 (35%), Positives = 47/85 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +A+ +FW D + I A++D KV + + + N+ NP IAV I+WTD ++
Sbjct: 477 DIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYNPAAIAVDWVYKTIYWTD--AAS 534
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
I A +DGT+R L S D++ P
Sbjct: 535 KTISVATLDGTKRKFLFNS-DLREP 558
>D16494-1|BAA03946.1| 845|Homo sapiens very low density lipoprotein
receptor protein.
Length = 845
Score = 68.1 bits (159), Expect = 2e-11
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW + I+WTD+ TI VA LD RK LF+ ++ P IAV P G ++W+DW
Sbjct: 521 DWVYKTIYWTDAASKTISVATLDGTKRKFLFN-SDLREPASIAVDPLSGFVYWSDWGEP- 578
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE A M+G +R L+ + D++ P
Sbjct: 579 AKIEKAGMNGFDRRPLV-TADIQWP 602
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/85 (35%), Positives = 47/85 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +A+ +FW D + I A++D KV + + + N+ NP IAV I+WTD ++
Sbjct: 477 DIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYNPAAIAVDWVYKTIYWTD--AAS 534
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
I A +DGT+R L S D++ P
Sbjct: 535 KTISVATLDGTKRKFLFNS-DLREP 558
>D16493-1|BAA03945.1| 873|Homo sapiens very low density lipoprotein
receptor protein.
Length = 873
Score = 68.1 bits (159), Expect = 2e-11
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW + I+WTD+ TI VA LD RK LF+ ++ P IAV P G ++W+DW
Sbjct: 521 DWVYKTIYWTDAASKTISVATLDGTKRKFLFN-SDLREPASIAVDPLSGFVYWSDWGEP- 578
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE A M+G +R L+ + D++ P
Sbjct: 579 AKIEKAGMNGFDRRPLV-TADIQWP 602
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/85 (35%), Positives = 47/85 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +A+ +FW D + I A++D KV + + + N+ NP IAV I+WTD ++
Sbjct: 477 DIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYNPAAIAVDWVYKTIYWTD--AAS 534
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
I A +DGT+R L S D++ P
Sbjct: 535 KTISVATLDGTKRKFLFNS-DLREP 558
>DQ067198-1|AAY46157.1| 873|Homo sapiens very low density
lipoprotein receptor protein.
Length = 873
Score = 68.1 bits (159), Expect = 2e-11
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW + I+WTD+ TI VA LD RK LF+ ++ P IAV P G ++W+DW
Sbjct: 521 DWVYKTIYWTDAASKTISVATLDGTKRKFLFN-SDLREPASIAVDPLSGFVYWSDWGEP- 578
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE A M+G +R L+ + D++ P
Sbjct: 579 AKIEKAGMNGFDRRPLV-TADIQWP 602
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/85 (35%), Positives = 47/85 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +A+ +FW D + I A++D KV + + + N+ NP IAV I+WTD ++
Sbjct: 477 DIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYNPAAIAVDWVYKTIYWTD--AAS 534
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
I A +DGT+R L S D++ P
Sbjct: 535 KTISVATLDGTKRKFLFNS-DLREP 558
>BC142653-1|AAI42654.1| 845|Homo sapiens very low density
lipoprotein receptor protein.
Length = 845
Score = 68.1 bits (159), Expect = 2e-11
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW + I+WTD+ TI VA LD RK LF+ ++ P IAV P G ++W+DW
Sbjct: 521 DWVYKTIYWTDAASKTISVATLDGTKRKFLFN-SDLREPASIAVDPLSGFVYWSDWGEP- 578
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE A M+G +R L+ + D++ P
Sbjct: 579 AKIEKAGMNGFDRRPLV-TADIQWP 602
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/85 (35%), Positives = 47/85 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +A+ +FW D + I A++D KV + + + N+ NP IAV I+WTD ++
Sbjct: 477 DIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYNPAAIAVDWVYKTIYWTD--AAS 534
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
I A +DGT+R L S D++ P
Sbjct: 535 KTISVATLDGTKRKFLFNS-DLREP 558
>AL450467-4|CAH72453.1| 752|Homo sapiens very low density
lipoprotein receptor protein.
Length = 752
Score = 68.1 bits (159), Expect = 2e-11
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW + I+WTD+ TI VA LD RK LF+ ++ P IAV P G ++W+DW
Sbjct: 400 DWVYKTIYWTDAASKTISVATLDGTKRKFLFN-SDLREPASIAVDPLSGFVYWSDWGEP- 457
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE A M+G +R L+ + D++ P
Sbjct: 458 AKIEKAGMNGFDRRPLV-TADIQWP 481
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/85 (35%), Positives = 47/85 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +A+ +FW D + I A++D KV + + + N+ NP IAV I+WTD ++
Sbjct: 356 DIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYNPAAIAVDWVYKTIYWTD--AAS 413
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
I A +DGT+R L S D++ P
Sbjct: 414 KTISVATLDGTKRKFLFNS-DLREP 437
>AL450467-3|CAH72455.1| 845|Homo sapiens very low density
lipoprotein receptor protein.
Length = 845
Score = 68.1 bits (159), Expect = 2e-11
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW + I+WTD+ TI VA LD RK LF+ ++ P IAV P G ++W+DW
Sbjct: 521 DWVYKTIYWTDAASKTISVATLDGTKRKFLFN-SDLREPASIAVDPLSGFVYWSDWGEP- 578
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE A M+G +R L+ + D++ P
Sbjct: 579 AKIEKAGMNGFDRRPLV-TADIQWP 602
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/85 (35%), Positives = 47/85 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +A+ +FW D + I A++D KV + + + N+ NP IAV I+WTD ++
Sbjct: 477 DIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYNPAAIAVDWVYKTIYWTD--AAS 534
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
I A +DGT+R L S D++ P
Sbjct: 535 KTISVATLDGTKRKFLFNS-DLREP 558
>AL450467-2|CAH72454.1| 873|Homo sapiens very low density
lipoprotein receptor protein.
Length = 873
Score = 68.1 bits (159), Expect = 2e-11
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW + I+WTD+ TI VA LD RK LF+ ++ P IAV P G ++W+DW
Sbjct: 521 DWVYKTIYWTDAASKTISVATLDGTKRKFLFN-SDLREPASIAVDPLSGFVYWSDWGEP- 578
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE A M+G +R L+ + D++ P
Sbjct: 579 AKIEKAGMNGFDRRPLV-TADIQWP 602
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/85 (35%), Positives = 47/85 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +A+ +FW D + I A++D KV + + + N+ NP IAV I+WTD ++
Sbjct: 477 DIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYNPAAIAVDWVYKTIYWTD--AAS 534
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
I A +DGT+R L S D++ P
Sbjct: 535 KTISVATLDGTKRKFLFNS-DLREP 558
>AK092381-1|BAC03874.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ35062 fis, clone OCBBF2019195, highly similar to
VERY LOW-DENSITY LIPOPROTEIN RECEPTOR PRECURSOR. ).
Length = 752
Score = 68.1 bits (159), Expect = 2e-11
Identities = 35/85 (41%), Positives = 50/85 (58%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW + I+WTD+ TI VA LD RK LF+ ++ P IAV P G ++W+DW
Sbjct: 400 DWVYKTIYWTDAASKTISVATLDGTKRKFLFN-SDLREPASIAVDPLSGFVYWSDWGEP- 457
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
KIE A M+G +R L+ + D++ P
Sbjct: 458 AKIEKAGMNGFDRRPLV-TADIQWP 481
Score = 52.8 bits (121), Expect = 1e-06
Identities = 30/85 (35%), Positives = 47/85 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
D +A+ +FW D + I A++D KV + + + N+ NP IAV I+WTD ++
Sbjct: 356 DIAAQKLFWADLSQKAIFSASIDDKVGRHVKMIDNVYNPAAIAVDWVYKTIYWTD--AAS 413
Query: 181 PKIEWANMDGTERSVLLGSPDVKLP 255
I A +DGT+R L S D++ P
Sbjct: 414 KTISVATLDGTKRKFLFNS-DLREP 437
>BC139736-1|AAI39737.1| 224|Homo sapiens LRP5L protein protein.
Length = 224
Score = 66.9 bits (156), Expect = 5e-11
Identities = 31/79 (39%), Positives = 50/79 (63%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
+W AR+++WT + IEV L++ K+L S +++ PR IA+HP+ G +W DW N
Sbjct: 42 NWVARSLYWTHTGTEHIEVTCLNSTSHKILVS-EDMDEPRAIALHPEMGLTYWIDWG-EN 99
Query: 181 PKIEWANMDGTERSVLLGS 237
P+I+ AN+D E VL+ +
Sbjct: 100 PEIKRANLDRQELRVLVNA 118
Score = 41.9 bits (94), Expect = 0.002
Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
Frame = +1
Query: 22 FWTD-SKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
+W D + I+ ANLD + +VL + ++ P G+A+ Q GK++W D KIE
Sbjct: 92 YWIDWGENPEIKRANLDRQELRVLVNA-SLGWPNGLALDLQEGKLYWGD--AKTDKIEAI 148
Query: 199 NMDGTERSVLLGSPDVKLPTLWPST 273
++D T+R LL KLP ++ T
Sbjct: 149 SVDETKRQTLLKD---KLPHIFRFT 170
>Y08110-1|CAA69325.1| 2214|Homo sapiens mosaic protein LR11 protein.
Length = 2214
Score = 61.3 bits (142), Expect = 3e-09
Identities = 31/79 (39%), Positives = 43/79 (54%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
++W D+ IEVAN D R + + + PR + + PQ G +FWTDW P I +
Sbjct: 846 LYWVDAGFKKIEVANPDGDFRLTIVNSSVLDRPRALVLVPQEGVMFWTDWGDLKPGIYRS 905
Query: 199 NMDGTERSVLLGSPDVKLP 255
NMDG+ L+ S DVK P
Sbjct: 906 NMDGSAAYHLV-SEDVKWP 923
Score = 40.7 bits (91), Expect = 0.004
Identities = 18/62 (29%), Positives = 34/62 (54%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
N +++D + + DA L+ I+ I +Q I +N +P+ +A+ +++YW DW L
Sbjct: 924 NGISVD--DQWIYWTDAYLECIERITFSGQQRSVILDNLPHPYAIAVFKNEIYWDDWSQL 981
Query: 435 KI 440
I
Sbjct: 982 SI 983
Score = 33.5 bits (73), Expect = 0.63
Identities = 17/52 (32%), Positives = 29/52 (55%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
I+WTD+ IE + R V+ + N+ +P IAV + +I+W DW++
Sbjct: 933 IYWTDAYLECIERITFSGQQRSVI--LDNLPHPYAIAVF--KNEIYWDDWSQ 980
>U60975-1|AAC50891.2| 2214|Homo sapiens gp250 precursor protein.
Length = 2214
Score = 61.3 bits (142), Expect = 3e-09
Identities = 31/79 (39%), Positives = 43/79 (54%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNPKIEWA 198
++W D+ IEVAN D R + + + PR + + PQ G +FWTDW P I +
Sbjct: 846 LYWVDAGFKKIEVANPDGDFRLTIVNSSVLDRPRALVLVPQEGVMFWTDWGDLKPGIYRS 905
Query: 199 NMDGTERSVLLGSPDVKLP 255
NMDG+ L+ S DVK P
Sbjct: 906 NMDGSAAYHLV-SEDVKWP 923
Score = 40.7 bits (91), Expect = 0.004
Identities = 18/62 (29%), Positives = 34/62 (54%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPFGLAINGDKLYWSDWRTL 434
N +++D + + DA L+ I+ I +Q I +N +P+ +A+ +++YW DW L
Sbjct: 924 NGISVD--DQWIYWTDAYLECIERITFSGQQRSVILDNLPHPYAIAVFKNEIYWDDWSQL 981
Query: 435 KI 440
I
Sbjct: 982 SI 983
Score = 33.5 bits (73), Expect = 0.63
Identities = 17/52 (32%), Positives = 29/52 (55%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
I+WTD+ IE + R V+ + N+ +P IAV + +I+W DW++
Sbjct: 933 IYWTDAYLECIERITFSGQQRSVI--LDNLPHPYAIAVF--KNEIYWDDWSQ 980
>AF283342-1|AAL38107.1| 881|Homo sapiens candidate tumor suppressor
protein protein.
Length = 881
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/105 (38%), Positives = 57/105 (54%), Gaps = 8/105 (7%)
Frame = +1
Query: 1 DWSARNIFWT-DSKKLTIEVANLD--TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN 171
DW N++WT D + TI VA L+ ++ RK L + +S+PRGI V P G ++WTDW
Sbjct: 607 DWIGNNLYWTNDGHRKTINVARLEKASQSRKTLLEGE-MSHPRGIVVDPVNGWMYWTDWE 665
Query: 172 R-----SNPKIEWANMDGTERSVLLGSPDVKLPTLWPSTGREIEF 291
S +IE A MDG R + + S LWP+ G ++F
Sbjct: 666 EDEIDDSVGRIEKAWMDGFNRQIFVTS-----KMLWPN-GLTLDF 704
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/79 (35%), Positives = 45/79 (56%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW RN+++ D I V N + V L ++ + NP+ IAV P GK+F+TD+ +
Sbjct: 291 DWLTRNLYFVDHVGDRIFVCNSNGSVCVTLIDLE-LHNPKAIAVDPIAGKLFFTDYG-NV 348
Query: 181 PKIEWANMDGTERSVLLGS 237
K+E +MDG R+ ++ S
Sbjct: 349 AKVERCDMDGMNRTRIIDS 367
Score = 35.5 bits (78), Expect = 0.16
Identities = 16/56 (28%), Positives = 32/56 (57%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDW 168
D+ ++W D+ IE L+ RK+++S + +++P G++ H +FWTD+
Sbjct: 703 DFHTNTLYWCDAYYDHIEKVFLNGTHRKIVYSGRELNHPFGLSHH--GNYVFWTDY 756
Score = 34.7 bits (76), Expect = 0.27
Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHS--RQIETIAENCRYPFGLAINGDKLYWSDWR 428
N + +D+ + + + DA I+ + L+ R+I +PFGL+ +G+ ++W+D+
Sbjct: 698 NGLTLDFHTNTLYWCDAYYDHIEKVFLNGTHRKIVYSGRELNHPFGLSHHGNYVFWTDYM 757
Query: 429 TLKIEIIDTIT 461
I +D IT
Sbjct: 758 NGSIFQLDLIT 768
>AC073319-1|AAX93075.1| 585|Homo sapiens unknown protein.
Length = 585
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/105 (38%), Positives = 57/105 (54%), Gaps = 8/105 (7%)
Frame = +1
Query: 1 DWSARNIFWT-DSKKLTIEVANLD--TKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN 171
DW N++WT D + TI VA L+ ++ RK L + +S+PRGI V P G ++WTDW
Sbjct: 269 DWIGNNLYWTNDGHRKTINVARLEKASQSRKTLLEGE-MSHPRGIVVDPVNGWMYWTDWE 327
Query: 172 R-----SNPKIEWANMDGTERSVLLGSPDVKLPTLWPSTGREIEF 291
S +IE A MDG R + + S LWP+ G ++F
Sbjct: 328 EDEIDDSVGRIEKAWMDGFNRQIFVTS-----KMLWPN-GLTLDF 366
Score = 35.5 bits (78), Expect = 0.16
Identities = 16/56 (28%), Positives = 32/56 (57%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDW 168
D+ ++W D+ IE L+ RK+++S + +++P G++ H +FWTD+
Sbjct: 365 DFHTNTLYWCDAYYDHIEKVFLNGTHRKIVYSGRELNHPFGLSHH--GNYVFWTDY 418
Score = 34.7 bits (76), Expect = 0.27
Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHS--RQIETIAENCRYPFGLAINGDKLYWSDWR 428
N + +D+ + + + DA I+ + L+ R+I +PFGL+ +G+ ++W+D+
Sbjct: 360 NGLTLDFHTNTLYWCDAYYDHIEKVFLNGTHRKIVYSGRELNHPFGLSHHGNYVFWTDYM 419
Query: 429 TLKIEIIDTIT 461
I +D IT
Sbjct: 420 NGSIFQLDLIT 430
>AC008178-1|AAY24266.1| 773|Homo sapiens unknown protein.
Length = 773
Score = 60.5 bits (140), Expect = 5e-09
Identities = 35/92 (38%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWN--R 174
DW I+ ++K I++ NLD R L + +N+ +PRGIAV P G +F++DW
Sbjct: 475 DWVNNKIYLVETKVNRIDMVNLDGSYRVTLIT-ENLGHPRGIAVDPTVGYLFFSDWESLS 533
Query: 175 SNPKIEWANMDGTERSVLLGSPDVKLPTLWPS 270
PK+E A MDG+ R L VK WP+
Sbjct: 534 GEPKLERAFMDGSNRKDL-----VKTKLGWPA 560
Score = 34.7 bits (76), Expect = 0.27
Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRK-VLFSVQNISNPRGIAVHPQRGKIFWTDWNR 174
D ++ ++W DS+ IE D RK V+ I +P G+++ G++F+TDW +
Sbjct: 565 DMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLF--EGQVFFTDWTK 621
Score = 29.9 bits (64), Expect = 7.7
Identities = 15/76 (19%), Positives = 36/76 (47%), Gaps = 3/76 (3%)
Frame = +3
Query: 261 VAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAEN---CRYPFGLAINGDKLYWSDWRT 431
V +D RV + D+ I+ + Q +T+ +PFG+++ +++++DW
Sbjct: 562 VTLDMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTK 621
Query: 432 LKIEIIDTITQARGQI 479
+ + + T+ Q+
Sbjct: 622 MAVLKANKFTETNPQV 637
>L00352-1|AAA56833.1| 860|Homo sapiens low density lipoprotein
receptor protein.
Length = 860
Score = 59.3 bits (137), Expect = 1e-08
Identities = 30/72 (41%), Positives = 41/72 (56%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW NI+WTDS T+ VA+ RK LF +N S PR I V P G ++WTDW +
Sbjct: 482 DWIHSNIYWTDSVLGTVSVADTKGVKRKTLFR-ENGSKPRAIVVDPVHGFMYWTDWG-TP 539
Query: 181 PKIEWANMDGTE 216
KI+ ++G +
Sbjct: 540 AKIKKGGLNGVD 551
Score = 38.3 bits (85), Expect = 0.022
Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 3/59 (5%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCR---YPFGLAINGDKLYWSD 422
N + +D R+ + D+ L I ID++ +TI E+ + +PF LA+ DK++W+D
Sbjct: 564 NGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTD 622
Score = 32.3 bits (70), Expect = 1.4
Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 3/65 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAINGDK--LYW 416
+A + +A+DW + + D+ L + D + +T+ EN P + ++ +YW
Sbjct: 474 QAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYW 533
Query: 417 SDWRT 431
+DW T
Sbjct: 534 TDWGT 538
>BT007361-1|AAP36025.1| 860|Homo sapiens low density lipoprotein
receptor (familial hypercholesterolemia) protein.
Length = 860
Score = 59.3 bits (137), Expect = 1e-08
Identities = 30/72 (41%), Positives = 41/72 (56%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW NI+WTDS T+ VA+ RK LF +N S PR I V P G ++WTDW +
Sbjct: 482 DWIHSNIYWTDSVLGTVSVADTKGVKRKTLFR-ENGSKPRAIVVDPVHGFMYWTDWG-TP 539
Query: 181 PKIEWANMDGTE 216
KI+ ++G +
Sbjct: 540 AKIKKGGLNGVD 551
Score = 38.3 bits (85), Expect = 0.022
Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 3/59 (5%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCR---YPFGLAINGDKLYWSD 422
N + +D R+ + D+ L I ID++ +TI E+ + +PF LA+ DK++W+D
Sbjct: 564 NGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTD 622
Score = 32.3 bits (70), Expect = 1.4
Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 3/65 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAINGDK--LYW 416
+A + +A+DW + + D+ L + D + +T+ EN P + ++ +YW
Sbjct: 474 QAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYW 533
Query: 417 SDWRT 431
+DW T
Sbjct: 534 TDWGT 538
>BC014514-1|AAH14514.1| 860|Homo sapiens low density lipoprotein
receptor (familial hypercholesterolemia) protein.
Length = 860
Score = 59.3 bits (137), Expect = 1e-08
Identities = 30/72 (41%), Positives = 41/72 (56%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW NI+WTDS T+ VA+ RK LF +N S PR I V P G ++WTDW +
Sbjct: 482 DWIHSNIYWTDSVLGTVSVADTKGVKRKTLFR-ENGSKPRAIVVDPVHGFMYWTDWG-TP 539
Query: 181 PKIEWANMDGTE 216
KI+ ++G +
Sbjct: 540 AKIKKGGLNGVD 551
Score = 38.3 bits (85), Expect = 0.022
Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 3/59 (5%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCR---YPFGLAINGDKLYWSD 422
N + +D R+ + D+ L I ID++ +TI E+ + +PF LA+ DK++W+D
Sbjct: 564 NGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTD 622
Score = 32.3 bits (70), Expect = 1.4
Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 3/65 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAINGDK--LYW 416
+A + +A+DW + + D+ L + D + +T+ EN P + ++ +YW
Sbjct: 474 QAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYW 533
Query: 417 SDWRT 431
+DW T
Sbjct: 534 TDWGT 538
>AY324609-1|AAP72971.1| 860|Homo sapiens low density lipoprotein
receptor protein.
Length = 860
Score = 59.3 bits (137), Expect = 1e-08
Identities = 30/72 (41%), Positives = 41/72 (56%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW NI+WTDS T+ VA+ RK LF +N S PR I V P G ++WTDW +
Sbjct: 482 DWIHSNIYWTDSVLGTVSVADTKGVKRKTLFR-ENGSKPRAIVVDPVHGFMYWTDWG-TP 539
Query: 181 PKIEWANMDGTE 216
KI+ ++G +
Sbjct: 540 AKIKKGGLNGVD 551
Score = 38.3 bits (85), Expect = 0.022
Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 3/59 (5%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCR---YPFGLAINGDKLYWSD 422
N + +D R+ + D+ L I ID++ +TI E+ + +PF LA+ DK++W+D
Sbjct: 564 NGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTD 622
Score = 32.3 bits (70), Expect = 1.4
Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 3/65 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAINGDK--LYW 416
+A + +A+DW + + D+ L + D + +T+ EN P + ++ +YW
Sbjct: 474 QAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYW 533
Query: 417 SDWRT 431
+DW T
Sbjct: 534 TDWGT 538
>AY114155-1|AAM56036.1| 860|Homo sapiens low density lipoprotein
receptor protein.
Length = 860
Score = 59.3 bits (137), Expect = 1e-08
Identities = 30/72 (41%), Positives = 41/72 (56%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW NI+WTDS T+ VA+ RK LF +N S PR I V P G ++WTDW +
Sbjct: 482 DWIHSNIYWTDSVLGTVSVADTKGVKRKTLFR-ENGSKPRAIVVDPVHGFMYWTDWG-TP 539
Query: 181 PKIEWANMDGTE 216
KI+ ++G +
Sbjct: 540 AKIKKGGLNGVD 551
Score = 38.3 bits (85), Expect = 0.022
Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 3/59 (5%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCR---YPFGLAINGDKLYWSD 422
N + +D R+ + D+ L I ID++ +TI E+ + +PF LA+ DK++W+D
Sbjct: 564 NGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTD 622
Score = 32.3 bits (70), Expect = 1.4
Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 3/65 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAINGDK--LYW 416
+A + +A+DW + + D+ L + D + +T+ EN P + ++ +YW
Sbjct: 474 QAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYW 533
Query: 417 SDWRT 431
+DW T
Sbjct: 534 TDWGT 538
>AF217403-1|AAF24515.1| 837|Homo sapiens low density lipoprotein
receptor protein.
Length = 837
Score = 59.3 bits (137), Expect = 1e-08
Identities = 30/72 (41%), Positives = 41/72 (56%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW NI+WTDS T+ VA+ RK LF +N S PR I V P G ++WTDW +
Sbjct: 459 DWIHSNIYWTDSVLGTVSVADTKGVKRKTLFR-ENGSKPRAIVVDPVHGFMYWTDWG-TP 516
Query: 181 PKIEWANMDGTE 216
KI+ ++G +
Sbjct: 517 AKIKKGGLNGVD 528
Score = 38.3 bits (85), Expect = 0.022
Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 3/59 (5%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCR---YPFGLAINGDKLYWSD 422
N + +D R+ + D+ L I ID++ +TI E+ + +PF LA+ DK++W+D
Sbjct: 541 NGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTD 599
Score = 32.3 bits (70), Expect = 1.4
Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 3/65 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAINGDK--LYW 416
+A + +A+DW + + D+ L + D + +T+ EN P + ++ +YW
Sbjct: 451 QAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYW 510
Query: 417 SDWRT 431
+DW T
Sbjct: 511 TDWGT 515
>AB209409-1|BAD92646.1| 870|Homo sapiens low density lipoprotein
receptor precursor variant protein.
Length = 870
Score = 59.3 bits (137), Expect = 1e-08
Identities = 30/72 (41%), Positives = 41/72 (56%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW NI+WTDS T+ VA+ RK LF +N S PR I V P G ++WTDW +
Sbjct: 494 DWIHSNIYWTDSVLGTVSVADTKGVKRKTLFR-ENGSKPRAIVVDPVHGFMYWTDWG-TP 551
Query: 181 PKIEWANMDGTE 216
KI+ ++G +
Sbjct: 552 AKIKKGGLNGVD 563
Score = 38.3 bits (85), Expect = 0.022
Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 3/59 (5%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCR---YPFGLAINGDKLYWSD 422
N + +D R+ + D+ L I ID++ +TI E+ + +PF LA+ DK++W+D
Sbjct: 576 NGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTD 634
Score = 32.3 bits (70), Expect = 1.4
Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 3/65 (4%)
Frame = +3
Query: 246 EASNSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETI-AENCRYPFGLAINGDK--LYW 416
+A + +A+DW + + D+ L + D + +T+ EN P + ++ +YW
Sbjct: 486 QAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYW 545
Query: 417 SDWRT 431
+DW T
Sbjct: 546 TDWGT 550
>AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppressor
protein protein.
Length = 1537
Score = 56.8 bits (131), Expect = 6e-08
Identities = 27/77 (35%), Positives = 46/77 (59%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW +N++W+D++K IEV+ L+ +L S + + PR +++ PQ G ++W D
Sbjct: 419 DWIGKNLYWSDTEKRIIEVSKLNGLYPTILVS-KRLKFPRDLSLDPQAGYLYWIDC-CEY 476
Query: 181 PKIEWANMDGTERSVLL 231
P I MDGT +SV++
Sbjct: 477 PHIGRVGMDGTNQSVVI 493
Score = 39.5 bits (88), Expect = 0.010
Identities = 31/100 (31%), Positives = 48/100 (48%), Gaps = 14/100 (14%)
Frame = +1
Query: 1 DWSARNIFWTDSKKL------TIEVANLDTKVRKVLFSVQNISN--------PRGIAVHP 138
DW A NI+WTD ++ T +L + + N + P IAV+P
Sbjct: 1301 DWVAGNIYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNMAGEPYAIAVNP 1360
Query: 139 QRGKIFWTDWNRSNPKIEWANMDGTERSVLLGSPDVKLPT 258
+RG ++WT + IE A MDGT R +L+ +++ PT
Sbjct: 1361 KRGMMYWTVVG-DHSHIEEAAMDGTLRRILV-QKNLQRPT 1398
Score = 31.1 bits (67), Expect = 3.3
Identities = 15/43 (34%), Positives = 25/43 (58%)
Frame = +1
Query: 49 IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRS 177
IE A +D +R++L +N+ P G+AV +I+W D+ S
Sbjct: 1376 IEEAAMDGTLRRILVQ-KNLQRPTGLAVDYFSERIYWADFELS 1417
>AB209707-1|BAD92944.1| 1720|Homo sapiens low density
lipoprotein-related protein 1B variant protein.
Length = 1720
Score = 56.8 bits (131), Expect = 6e-08
Identities = 27/77 (35%), Positives = 46/77 (59%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW +N++W+D++K IEV+ L+ +L S + + PR +++ PQ G ++W D
Sbjct: 216 DWIGKNLYWSDTEKRIIEVSKLNGLYPTILVS-KRLKFPRDLSLDPQAGYLYWIDC-CEY 273
Query: 181 PKIEWANMDGTERSVLL 231
P I MDGT +SV++
Sbjct: 274 PHIGRVGMDGTNQSVVI 290
Score = 39.5 bits (88), Expect = 0.010
Identities = 31/100 (31%), Positives = 48/100 (48%), Gaps = 14/100 (14%)
Frame = +1
Query: 1 DWSARNIFWTDSKKL------TIEVANLDTKVRKVLFSVQNISN--------PRGIAVHP 138
DW A NI+WTD ++ T +L + + N + P IAV+P
Sbjct: 1098 DWVAGNIYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNMAGEPYAIAVNP 1157
Query: 139 QRGKIFWTDWNRSNPKIEWANMDGTERSVLLGSPDVKLPT 258
+RG ++WT + IE A MDGT R +L+ +++ PT
Sbjct: 1158 KRGMMYWTVVG-DHSHIEEAAMDGTLRRILV-QKNLQRPT 1195
Score = 31.1 bits (67), Expect = 3.3
Identities = 15/43 (34%), Positives = 25/43 (58%)
Frame = +1
Query: 49 IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRS 177
IE A +D +R++L +N+ P G+AV +I+W D+ S
Sbjct: 1173 IEEAAMDGTLRRILVQ-KNLQRPTGLAVDYFSERIYWADFELS 1214
>BC021204-1|AAH21204.1| 439|Homo sapiens LRP1 protein protein.
Length = 439
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/79 (35%), Positives = 44/79 (55%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSN 180
DW N ++ D I V N + L ++ + NP+GIA+ P GK+F+TD+ +
Sbjct: 288 DWLTGNFYFVDDIDDRIFVCNRNGDTCVTLLDLE-LYNPKGIALDPAMGKVFFTDYGQI- 345
Query: 181 PKIEWANMDGTERSVLLGS 237
PK+E +MDG R+ L+ S
Sbjct: 346 PKVERCDMDGQNRTKLVDS 364
>AC093039-1|AAX88911.1| 425|Homo sapiens unknown protein.
Length = 425
Score = 40.7 bits (91), Expect = 0.004
Identities = 17/49 (34%), Positives = 31/49 (63%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRG 147
DW +N++W+D++K IEV+ L+ +L S + + PR +++ PQ G
Sbjct: 378 DWIGKNLYWSDTEKRIIEVSKLNGLYPTILVS-KRLKFPRDLSLDPQAG 425
>AC068195-1|AAX93243.1| 1126|Homo sapiens unknown protein.
Length = 1126
Score = 39.5 bits (88), Expect = 0.010
Identities = 31/100 (31%), Positives = 48/100 (48%), Gaps = 14/100 (14%)
Frame = +1
Query: 1 DWSARNIFWTDSKKL------TIEVANLDTKVRKVLFSVQNISN--------PRGIAVHP 138
DW A NI+WTD ++ T +L + + N + P IAV+P
Sbjct: 835 DWVAGNIYWTDHSRMHWFSYYTTHWTSLRYSINVGQLNGPNCTRLLTNMAGEPYAIAVNP 894
Query: 139 QRGKIFWTDWNRSNPKIEWANMDGTERSVLLGSPDVKLPT 258
+RG ++WT + IE A MDGT R +L+ +++ PT
Sbjct: 895 KRGMMYWTVVG-DHSHIEEAAMDGTLRRILV-QKNLQRPT 932
Score = 31.1 bits (67), Expect = 3.3
Identities = 15/43 (34%), Positives = 25/43 (58%)
Frame = +1
Query: 49 IEVANLDTKVRKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRS 177
IE A +D +R++L +N+ P G+AV +I+W D+ S
Sbjct: 910 IEEAAMDGTLRRILVQ-KNLQRPTGLAVDYFSERIYWADFELS 951
>AC108036-1|AAX93208.1| 449|Homo sapiens unknown protein.
Length = 449
Score = 36.7 bits (81), Expect = 0.067
Identities = 21/84 (25%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Frame = +1
Query: 19 IFWTDSKKLTIEVANLD-TKV----RKVLFSVQNISNPRGIAVHPQRGKIFWTDWNRSNP 183
++WT S +I +D T+ R+ + ++ +P +A+ + +FWT+WN +P
Sbjct: 16 LYWTSSTTSSITRHTVDQTRPGAFDREAVITMSEDDHPHVLALDECQNLMFWTNWNEQHP 75
Query: 184 KIEWANMDGTERSVLLGSPDVKLP 255
I + + G V++ S D+ P
Sbjct: 76 SIMRSTLTGKNAQVVV-STDILTP 98
Score = 32.7 bits (71), Expect = 1.1
Identities = 16/58 (27%), Positives = 30/58 (51%), Gaps = 1/58 (1%)
Frame = +3
Query: 255 NSVAIDWSRDRVCFADAGLQVIKCIDLHSRQIETIAENCRYPF-GLAINGDKLYWSDW 425
N + ID+ +++ F+D L I+ + Q I ++ F LA+ + ++WSDW
Sbjct: 99 NGLTIDYRAEKLYFSDGSLGKIERCEYDGSQRHVIVKSGPGTFLSLAVYDNYIFWSDW 156
>AC068287-1|AAY24318.1| 223|Homo sapiens unknown protein.
Length = 223
Score = 31.1 bits (67), Expect = 3.3
Identities = 17/49 (34%), Positives = 25/49 (51%)
Frame = +1
Query: 1 DWSARNIFWTDSKKLTIEVANLDTKVRKVLFSVQNISNPRGIAVHPQRG 147
DW RN+++ D I V N + V L ++ + NP+ IAV P G
Sbjct: 176 DWLTRNLYFVDHVGDRIFVCNSNGSVCVTLIDLE-LHNPKAIAVDPIAG 223
>AK123991-1|BAC85745.1| 155|Homo sapiens protein ( Homo sapiens
cDNA FLJ41997 fis, clone SPLEN2029176. ).
Length = 155
Score = 30.7 bits (66), Expect = 4.4
Identities = 17/52 (32%), Positives = 25/52 (48%)
Frame = -1
Query: 349 ICRLCRSMHLMTWRPASAKQTRSLDQSMATELEASHLGYRGGLIFPCRPCSP 194
+C L S H M WRP + + R + Q + E G+ G L+ PC +P
Sbjct: 37 VC-LAGSKHFMEWRPLAVRDLRKICQGL-LHSEGLQFGWLGTLL-PCTDGAP 85
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 97,400,300
Number of Sequences: 237096
Number of extensions: 2188006
Number of successful extensions: 11006
Number of sequences better than 10.0: 87
Number of HSP's better than 10.0 without gapping: 9626
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10724
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6804036910
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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