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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= heS30114
         (716 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

D50063-1|BAA08780.1|  324|Homo sapiens proteasome subunit p40 / ...   170   4e-42
BC012606-1|AAH12606.1|  324|Homo sapiens proteasome (prosome, ma...   170   4e-42
BC000338-1|AAH00338.1|  326|Homo sapiens PSMD7 protein protein.       170   4e-42
U94855-1|AAD03467.1|  357|Homo sapiens translation initiation fa...    58   2e-08
CR456959-1|CAG33240.1|  357|Homo sapiens EIF3S5 protein.               58   2e-08
BT006894-1|AAP35540.1|  357|Homo sapiens eukaryotic translation ...    58   2e-08
BC000490-1|AAH00490.1|  357|Homo sapiens eukaryotic translation ...    58   2e-08
AK095574-1|BAC04577.1|  350|Homo sapiens protein ( Homo sapiens ...    58   2e-08
AF354444-1|AAK18634.1|  348|Homo sapiens IFP38 protein.                53   9e-07
U86782-1|AAC51866.1|  310|Homo sapiens 26S proteasome-associated...    32   2.4  
U70734-1|AAD03468.1|  334|Homo sapiens 38 kDa Mov34 homolog prot...    32   2.4  
CR541678-1|CAG46479.1|  334|Homo sapiens COPS5 protein.                32   2.4  
BC066336-1|AAH66336.1|  310|Homo sapiens proteasome (prosome, ma...    32   2.4  
BC007272-1|AAH07272.1|  334|Homo sapiens COP9 constitutive photo...    32   2.4  
BC001859-1|AAH01859.1|  334|Homo sapiens COP9 constitutive photo...    32   2.4  
BC001187-1|AAH01187.1|  334|Homo sapiens COP9 constitutive photo...    32   2.4  
AC009299-2|AAX88940.1|  154|Homo sapiens unknown protein.              32   2.4  
AB209134-1|BAD92371.1|  276|Homo sapiens COP9 signalosome subuni...    32   2.4  
U65928-1|AAB16847.1|  334|Homo sapiens Jun activation domain bin...    31   3.1  

>D50063-1|BAA08780.1|  324|Homo sapiens proteasome subunit p40 /
           Mov34 protein protein.
          Length = 324

 Score =  170 bits (414), Expect = 4e-42
 Identities = 76/93 (81%), Positives = 85/93 (91%)
 Frame = +2

Query: 254 MGCWRAKGVLDVSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTG 433
           +G W+ K VLDVSNSFAVPFDEDDKD SVWFLDHDYLENMYGMFKKVNARE++VGWYHTG
Sbjct: 40  LGSWQKK-VLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTG 98

Query: 434 PKLHQNDIAINELIRRYCPNSVLVILMLNLKIL 532
           PKLH+NDIAINEL++RYCPNSVLVI+ +  K L
Sbjct: 99  PKLHKNDIAINELMKRYCPNSVLVIIDVKPKDL 131



 Score = 97.9 bits (233), Expect = 3e-20
 Identities = 48/68 (70%), Positives = 51/68 (75%)
 Frame = +1

Query: 511 DAKPKDLGLPTEAYQAVEEVHDDGTPTSRTFEHVPSEIXXXXXXXXXXXHLLRDIKGTTV 690
           D KPKDLGLPTEAY +VEE  DDGTPTS+TFEHV SEI           HLLRDIK TTV
Sbjct: 125 DVKPKDLGLPTEAYISVEEDQDDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTV 184

Query: 691 GSLSQRIT 714
           G+LSQRIT
Sbjct: 185 GTLSQRIT 192



 Score = 39.1 bits (87), Expect = 0.016
 Identities = 16/19 (84%), Positives = 18/19 (94%)
 Frame = +3

Query: 198 DHFNRMSKIGNQKRVVGVL 254
           DHFNR+ K+GNQKRVVGVL
Sbjct: 21  DHFNRIVKVGNQKRVVGVL 39


>BC012606-1|AAH12606.1|  324|Homo sapiens proteasome (prosome,
           macropain) 26S subunit, non-ATPase, 7 (Mov34 homolog)
           protein.
          Length = 324

 Score =  170 bits (414), Expect = 4e-42
 Identities = 76/93 (81%), Positives = 85/93 (91%)
 Frame = +2

Query: 254 MGCWRAKGVLDVSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTG 433
           +G W+ K VLDVSNSFAVPFDEDDKD SVWFLDHDYLENMYGMFKKVNARE++VGWYHTG
Sbjct: 40  LGSWQKK-VLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTG 98

Query: 434 PKLHQNDIAINELIRRYCPNSVLVILMLNLKIL 532
           PKLH+NDIAINEL++RYCPNSVLVI+ +  K L
Sbjct: 99  PKLHKNDIAINELMKRYCPNSVLVIIDVKPKDL 131



 Score =  103 bits (248), Expect = 5e-22
 Identities = 50/68 (73%), Positives = 53/68 (77%)
 Frame = +1

Query: 511 DAKPKDLGLPTEAYQAVEEVHDDGTPTSRTFEHVPSEIXXXXXXXXXXXHLLRDIKGTTV 690
           D KPKDLGLPTEAY +VEEVHDDGTPTS+TFEHV SEI           HLLRDIK TTV
Sbjct: 125 DVKPKDLGLPTEAYISVEEVHDDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTV 184

Query: 691 GSLSQRIT 714
           G+LSQRIT
Sbjct: 185 GTLSQRIT 192



 Score = 39.9 bits (89), Expect = 0.009
 Identities = 16/19 (84%), Positives = 18/19 (94%)
 Frame = +3

Query: 198 DHFNRMSKIGNQKRVVGVL 254
           DHFNR+ K+GNQKRVVGVL
Sbjct: 21  DHFNRIGKVGNQKRVVGVL 39


>BC000338-1|AAH00338.1|  326|Homo sapiens PSMD7 protein protein.
          Length = 326

 Score =  170 bits (414), Expect = 4e-42
 Identities = 76/93 (81%), Positives = 85/93 (91%)
 Frame = +2

Query: 254 MGCWRAKGVLDVSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTG 433
           +G W+ K VLDVSNSFAVPFDEDDKD SVWFLDHDYLENMYGMFKKVNARE++VGWYHTG
Sbjct: 40  LGSWQKK-VLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTG 98

Query: 434 PKLHQNDIAINELIRRYCPNSVLVILMLNLKIL 532
           PKLH+NDIAINEL++RYCPNSVLVI+ +  K L
Sbjct: 99  PKLHKNDIAINELMKRYCPNSVLVIIDVKPKDL 131



 Score =  103 bits (248), Expect = 5e-22
 Identities = 50/68 (73%), Positives = 53/68 (77%)
 Frame = +1

Query: 511 DAKPKDLGLPTEAYQAVEEVHDDGTPTSRTFEHVPSEIXXXXXXXXXXXHLLRDIKGTTV 690
           D KPKDLGLPTEAY +VEEVHDDGTPTS+TFEHV SEI           HLLRDIK TTV
Sbjct: 125 DVKPKDLGLPTEAYISVEEVHDDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTV 184

Query: 691 GSLSQRIT 714
           G+LSQRIT
Sbjct: 185 GTLSQRIT 192



 Score = 39.9 bits (89), Expect = 0.009
 Identities = 16/19 (84%), Positives = 18/19 (94%)
 Frame = +3

Query: 198 DHFNRMSKIGNQKRVVGVL 254
           DHFNR+ K+GNQKRVVGVL
Sbjct: 21  DHFNRIGKVGNQKRVVGVL 39


>U94855-1|AAD03467.1|  357|Homo sapiens translation initiation
           factor 3 47 kDa subunit protein.
          Length = 357

 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 26/76 (34%), Positives = 47/76 (61%)
 Frame = +2

Query: 272 KGVLDVSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGPKLHQN 451
           K  ++V+N F+VP +E + + +V   D ++ +NMY + KKV+  E ++GWY TG  + ++
Sbjct: 126 KHSVEVTNCFSVPHNESEDEVAV---DMEFAKNMYELHKKVSPNELILGWYATGHDITEH 182

Query: 452 DIAINELIRRYCPNSV 499
            + I+E   R  PN +
Sbjct: 183 SVLIHEYYSREAPNPI 198


>CR456959-1|CAG33240.1|  357|Homo sapiens EIF3S5 protein.
          Length = 357

 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 26/76 (34%), Positives = 47/76 (61%)
 Frame = +2

Query: 272 KGVLDVSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGPKLHQN 451
           K  ++V+N F+VP +E + + +V   D ++ +NMY + KKV+  E ++GWY TG  + ++
Sbjct: 126 KHSVEVTNCFSVPHNESEDEVAV---DMEFAKNMYELHKKVSPNELILGWYATGHDITEH 182

Query: 452 DIAINELIRRYCPNSV 499
            + I+E   R  PN +
Sbjct: 183 SVLIHEYYSREAPNPI 198


>BT006894-1|AAP35540.1|  357|Homo sapiens eukaryotic translation
           initiation factor 3, subunit 5 epsilon, 47kDa protein.
          Length = 357

 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 26/76 (34%), Positives = 47/76 (61%)
 Frame = +2

Query: 272 KGVLDVSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGPKLHQN 451
           K  ++V+N F+VP +E + + +V   D ++ +NMY + KKV+  E ++GWY TG  + ++
Sbjct: 126 KHSVEVTNCFSVPHNESEDEVAV---DMEFAKNMYELHKKVSPNELILGWYATGHDITEH 182

Query: 452 DIAINELIRRYCPNSV 499
            + I+E   R  PN +
Sbjct: 183 SVLIHEYYSREAPNPI 198


>BC000490-1|AAH00490.1|  357|Homo sapiens eukaryotic translation
           initiation factor 3, subunit 5 epsilon, 47kDa protein.
          Length = 357

 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 26/76 (34%), Positives = 47/76 (61%)
 Frame = +2

Query: 272 KGVLDVSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGPKLHQN 451
           K  ++V+N F+VP +E + + +V   D ++ +NMY + KKV+  E ++GWY TG  + ++
Sbjct: 126 KHSVEVTNCFSVPHNESEDEVAV---DMEFAKNMYELHKKVSPNELILGWYATGHDITEH 182

Query: 452 DIAINELIRRYCPNSV 499
            + I+E   R  PN +
Sbjct: 183 SVLIHEYYSREAPNPI 198


>AK095574-1|BAC04577.1|  350|Homo sapiens protein ( Homo sapiens
           cDNA FLJ38255 fis, clone FCBBF3001020, highly similar to
           EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 5. ).
          Length = 350

 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 26/76 (34%), Positives = 47/76 (61%)
 Frame = +2

Query: 272 KGVLDVSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGPKLHQN 451
           K  ++V+N F+VP +E + + +V   D ++ +NMY + KKV+  E ++GWY TG  + ++
Sbjct: 119 KHSVEVTNCFSVPHNESEDEVAV---DMEFAKNMYELHKKVSPNELILGWYATGHDITEH 175

Query: 452 DIAINELIRRYCPNSV 499
            + I+E   R  PN +
Sbjct: 176 SVLIHEYYSREAPNPI 191


>AF354444-1|AAK18634.1|  348|Homo sapiens IFP38 protein.
          Length = 348

 Score = 53.2 bits (122), Expect = 9e-07
 Identities = 24/76 (31%), Positives = 45/76 (59%)
 Frame = +2

Query: 272 KGVLDVSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGPKLHQN 451
           K  ++V+N F+V ++E D+      +D ++ +NMY + KKV+  E ++GWY  G  + ++
Sbjct: 116 KHSVEVTNCFSVSYNESDEV----VVDMEFAKNMYELHKKVSPNELILGWYAAGHDITEH 171

Query: 452 DIAINELIRRYCPNSV 499
            + I+E   R  PN +
Sbjct: 172 SVLIHEYYSREAPNPI 187


>U86782-1|AAC51866.1|  310|Homo sapiens 26S proteasome-associated
           pad1 homolog protein.
          Length = 310

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 18/50 (36%), Positives = 25/50 (50%)
 Frame = +2

Query: 287 VSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGP 436
           V + FA+P  +     SV  +D  +   M  M K+    E VVGWYH+ P
Sbjct: 69  VIDVFAMP--QSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHP 116


>U70734-1|AAD03468.1|  334|Homo sapiens 38 kDa Mov34 homolog
           protein.
          Length = 334

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/50 (26%), Positives = 25/50 (50%)
 Frame = +2

Query: 287 VSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGP 436
           + +SFA+P +  +   +     ++Y+       K+V   E  +GWYH+ P
Sbjct: 92  IMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHP 141


>CR541678-1|CAG46479.1|  334|Homo sapiens COPS5 protein.
          Length = 334

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/50 (26%), Positives = 25/50 (50%)
 Frame = +2

Query: 287 VSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGP 436
           + +SFA+P +  +   +     ++Y+       K+V   E  +GWYH+ P
Sbjct: 92  IMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHP 141


>BC066336-1|AAH66336.1|  310|Homo sapiens proteasome (prosome,
           macropain) 26S subunit, non-ATPase, 14 protein.
          Length = 310

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 18/50 (36%), Positives = 25/50 (50%)
 Frame = +2

Query: 287 VSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGP 436
           V + FA+P  +     SV  +D  +   M  M K+    E VVGWYH+ P
Sbjct: 69  VIDVFAMP--QSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHP 116


>BC007272-1|AAH07272.1|  334|Homo sapiens COP9 constitutive
           photomorphogenic homolog subunit 5 (Arabidopsis)
           protein.
          Length = 334

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/50 (26%), Positives = 25/50 (50%)
 Frame = +2

Query: 287 VSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGP 436
           + +SFA+P +  +   +     ++Y+       K+V   E  +GWYH+ P
Sbjct: 92  IMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHP 141


>BC001859-1|AAH01859.1|  334|Homo sapiens COP9 constitutive
           photomorphogenic homolog subunit 5 (Arabidopsis)
           protein.
          Length = 334

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/50 (26%), Positives = 25/50 (50%)
 Frame = +2

Query: 287 VSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGP 436
           + +SFA+P +  +   +     ++Y+       K+V   E  +GWYH+ P
Sbjct: 92  IMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHP 141


>BC001187-1|AAH01187.1|  334|Homo sapiens COP9 constitutive
           photomorphogenic homolog subunit 5 (Arabidopsis)
           protein.
          Length = 334

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/50 (26%), Positives = 25/50 (50%)
 Frame = +2

Query: 287 VSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGP 436
           + +SFA+P +  +   +     ++Y+       K+V   E  +GWYH+ P
Sbjct: 92  IMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHP 141


>AC009299-2|AAX88940.1|  154|Homo sapiens unknown protein.
          Length = 154

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 18/50 (36%), Positives = 25/50 (50%)
 Frame = +2

Query: 287 VSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGP 436
           V + FA+P  +     SV  +D  +   M  M K+    E VVGWYH+ P
Sbjct: 69  VIDVFAMP--QSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHP 116


>AB209134-1|BAD92371.1|  276|Homo sapiens COP9 signalosome subunit 5
           variant protein.
          Length = 276

 Score = 31.9 bits (69), Expect = 2.4
 Identities = 13/50 (26%), Positives = 25/50 (50%)
 Frame = +2

Query: 287 VSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGP 436
           + +SFA+P +  +   +     ++Y+       K+V   E  +GWYH+ P
Sbjct: 61  IMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHP 110


>U65928-1|AAB16847.1|  334|Homo sapiens Jun activation domain
           binding protein protein.
          Length = 334

 Score = 31.5 bits (68), Expect = 3.1
 Identities = 13/50 (26%), Positives = 25/50 (50%)
 Frame = +2

Query: 287 VSNSFAVPFDEDDKDKSVWFLDHDYLENMYGMFKKVNAREKVVGWYHTGP 436
           + +SFA+P +  +   +     ++Y+       K+V   E  +GWYH+ P
Sbjct: 92  IMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGHLENAIGWYHSHP 141


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 95,632,464
Number of Sequences: 237096
Number of extensions: 1828562
Number of successful extensions: 3395
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 3271
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3395
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8399192100
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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