Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= heS00641X
(547 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D49387-1|BAA08382.1| 311|Homo sapiens NADP dependent leukotrien... 88 2e-17
BC035228-1|AAH35228.1| 329|Homo sapiens leukotriene B4 12-hydro... 88 2e-17
AL135787-3|CAC22151.1| 329|Homo sapiens leukotriene B4 12-hydro... 88 2e-17
AL135787-2|CAI12401.1| 177|Homo sapiens leukotriene B4 12-hydro... 88 2e-17
BC059364-1|AAH59364.1| 351|Homo sapiens zinc binding alcohol de... 68 2e-11
AY424308-1|AAR82927.1| 351|Homo sapiens zinc binding alcohol de... 68 2e-11
AY346133-1|AAR05101.1| 351|Homo sapiens zinc binding alcohol de... 68 2e-11
AK096410-1|BAC04781.1| 351|Homo sapiens protein ( Homo sapiens ... 68 2e-11
BC078661-1|AAH78661.1| 377|Homo sapiens zinc binding alcohol de... 48 2e-05
BC033780-1|AAH33780.1| 377|Homo sapiens zinc binding alcohol de... 48 2e-05
BC018081-1|AAH18081.1| 366|Homo sapiens ZADH2 protein protein. 47 4e-05
AK223201-1|BAD96921.1| 329|Homo sapiens crystallin, zeta varian... 31 2.6
AK223150-1|BAD96870.1| 329|Homo sapiens crystallin, zeta varian... 31 2.6
AB209714-1|BAD92951.1| 331|Homo sapiens crystallin, zeta varian... 31 2.6
L31526-1|AAK40311.1| 329|Homo sapiens zeta-crystallin protein. 31 3.5
L13278-1|AAA36536.1| 329|Homo sapiens zeta-crystallin protein. 31 3.5
BC070058-1|AAH70058.1| 329|Homo sapiens CRYZ protein protein. 31 3.5
BC039578-1|AAH39578.1| 329|Homo sapiens crystallin, zeta (quino... 31 3.5
>D49387-1|BAA08382.1| 311|Homo sapiens NADP dependent leukotriene
b4 12-hydroxydehydrogenase protein.
Length = 311
Score = 87.8 bits (208), Expect = 2e-17
Identities = 43/85 (50%), Positives = 57/85 (67%), Gaps = 1/85 (1%)
Frame = +2
Query: 2 EICKPKXXXXXXXXXXXXXXXSLVGQIAKIKGCRVIGFAGTDDKVKWLEEELGFDKAFNY 181
EIC K S+VGQIAK+KGC+V+G G+D+KV +L ++LGFD FNY
Sbjct: 135 EICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYL-QKLGFDVVFNY 193
Query: 182 KTVD-VPAALKEAAPNGIDCYFDNV 253
KTV+ + LK+A+P+G DCYFDNV
Sbjct: 194 KTVESLEETLKKASPDGYDCYFDNV 218
Score = 64.1 bits (149), Expect = 3e-10
Identities = 30/89 (33%), Positives = 55/89 (61%), Gaps = 3/89 (3%)
Frame = +1
Query: 241 FRQCRGEISSQIISKMNVYGRVSVCGSISAYNEDLTKLPKATILQPSLV-FNQIKVEGFL 417
F GE S+ +I +M +GR+++CG+IS YN LP P +V + ++++E F+
Sbjct: 215 FDNVGGEFSNTVIGQMKKFGRIAICGAISTYNR-TGPLPPGP--PPEIVIYQELRMEAFV 271
Query: 418 VWRW--NAQSKAFAEIIPWIQSGKLKVKD 498
V+RW +A+ KA +++ W+ GK++ K+
Sbjct: 272 VYRWQGDARQKALKDLLKWVLEGKIQYKE 300
>BC035228-1|AAH35228.1| 329|Homo sapiens leukotriene B4
12-hydroxydehydrogenase protein.
Length = 329
Score = 87.8 bits (208), Expect = 2e-17
Identities = 43/85 (50%), Positives = 57/85 (67%), Gaps = 1/85 (1%)
Frame = +2
Query: 2 EICKPKXXXXXXXXXXXXXXXSLVGQIAKIKGCRVIGFAGTDDKVKWLEEELGFDKAFNY 181
EIC K S+VGQIAK+KGC+V+G G+D+KV +L ++LGFD FNY
Sbjct: 135 EICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYL-QKLGFDVVFNY 193
Query: 182 KTVD-VPAALKEAAPNGIDCYFDNV 253
KTV+ + LK+A+P+G DCYFDNV
Sbjct: 194 KTVESLEETLKKASPDGYDCYFDNV 218
Score = 64.1 bits (149), Expect = 3e-10
Identities = 30/89 (33%), Positives = 55/89 (61%), Gaps = 3/89 (3%)
Frame = +1
Query: 241 FRQCRGEISSQIISKMNVYGRVSVCGSISAYNEDLTKLPKATILQPSLV-FNQIKVEGFL 417
F GE S+ +I +M +GR+++CG+IS YN LP P +V + ++++E F+
Sbjct: 215 FDNVGGEFSNTVIGQMKKFGRIAICGAISTYNR-TGPLPPGP--PPEIVIYQELRMEAFV 271
Query: 418 VWRW--NAQSKAFAEIIPWIQSGKLKVKD 498
V+RW +A+ KA +++ W+ GK++ K+
Sbjct: 272 VYRWQGDARQKALKDLLKWVLEGKIQYKE 300
>AL135787-3|CAC22151.1| 329|Homo sapiens leukotriene B4
12-hydroxydehydrogenase protein.
Length = 329
Score = 87.8 bits (208), Expect = 2e-17
Identities = 43/85 (50%), Positives = 57/85 (67%), Gaps = 1/85 (1%)
Frame = +2
Query: 2 EICKPKXXXXXXXXXXXXXXXSLVGQIAKIKGCRVIGFAGTDDKVKWLEEELGFDKAFNY 181
EIC K S+VGQIAK+KGC+V+G G+D+KV +L ++LGFD FNY
Sbjct: 135 EICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYL-QKLGFDVVFNY 193
Query: 182 KTVD-VPAALKEAAPNGIDCYFDNV 253
KTV+ + LK+A+P+G DCYFDNV
Sbjct: 194 KTVESLEETLKKASPDGYDCYFDNV 218
Score = 64.1 bits (149), Expect = 3e-10
Identities = 30/89 (33%), Positives = 55/89 (61%), Gaps = 3/89 (3%)
Frame = +1
Query: 241 FRQCRGEISSQIISKMNVYGRVSVCGSISAYNEDLTKLPKATILQPSLV-FNQIKVEGFL 417
F GE S+ +I +M +GR+++CG+IS YN LP P +V + ++++E F+
Sbjct: 215 FDNVGGEFSNTVIGQMKKFGRIAICGAISTYNR-TGPLPPGP--PPEIVIYQELRMEAFV 271
Query: 418 VWRW--NAQSKAFAEIIPWIQSGKLKVKD 498
V+RW +A+ KA +++ W+ GK++ K+
Sbjct: 272 VYRWQGDARQKALKDLLKWVLEGKIQYKE 300
>AL135787-2|CAI12401.1| 177|Homo sapiens leukotriene B4
12-hydroxydehydrogenase protein.
Length = 177
Score = 87.8 bits (208), Expect = 2e-17
Identities = 43/85 (50%), Positives = 57/85 (67%), Gaps = 1/85 (1%)
Frame = +2
Query: 2 EICKPKXXXXXXXXXXXXXXXSLVGQIAKIKGCRVIGFAGTDDKVKWLEEELGFDKAFNY 181
EIC K S+VGQIAK+KGC+V+G G+D+KV +L ++LGFD FNY
Sbjct: 12 EICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYL-QKLGFDVVFNY 70
Query: 182 KTVD-VPAALKEAAPNGIDCYFDNV 253
KTV+ + LK+A+P+G DCYFDNV
Sbjct: 71 KTVESLEETLKKASPDGYDCYFDNV 95
Score = 56.8 bits (131), Expect = 5e-08
Identities = 27/80 (33%), Positives = 49/80 (61%), Gaps = 3/80 (3%)
Frame = +1
Query: 241 FRQCRGEISSQIISKMNVYGRVSVCGSISAYNEDLTKLPKATILQPSLV-FNQIKVEGFL 417
F GE S+ +I +M +GR+++CG+IS YN LP P +V + ++++E F+
Sbjct: 92 FDNVGGEFSNTVIGQMKKFGRIAICGAISTYNR-TGPLPPGP--PPEIVIYQELRMEAFV 148
Query: 418 VWRW--NAQSKAFAEIIPWI 471
V+RW +A+ KA +++ W+
Sbjct: 149 VYRWQGDARQKALKDLLKWV 168
>BC059364-1|AAH59364.1| 351|Homo sapiens zinc binding alcohol
dehydrogenase, domain containing 1 protein.
Length = 351
Score = 68.1 bits (159), Expect = 2e-11
Identities = 33/64 (51%), Positives = 40/64 (62%), Gaps = 1/64 (1%)
Frame = +2
Query: 65 SLVGQIAKIKGC-RVIGFAGTDDKVKWLEEELGFDKAFNYKTVDVPAALKEAAPNGIDCY 241
S+ GQI GC RV+G GT +K L ELGFD A NYK +V L+E+ P G+D Y
Sbjct: 169 SVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVY 228
Query: 242 FDNV 253
FDNV
Sbjct: 229 FDNV 232
Score = 50.4 bits (115), Expect = 4e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Frame = +1
Query: 214 SCP*RDRLLFRQCRGEISSQIISKMNVYGRVSVCGSISAYNEDLT-KLPKATILQPSLVF 390
SCP + F G IS +IS+MN + +CG IS YN+D+ P + ++
Sbjct: 220 SCPAGVDVYFDNVGGNISDTVISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKE 279
Query: 391 NQIKVEGFLVWRWNAQ-SKAFAEIIPWIQSGKLKVKD 498
I E FLV + + ++ W + GKLK+K+
Sbjct: 280 RNITRERFLVLNYKDKFEPGILQLSQWFKEGKLKIKE 316
>AY424308-1|AAR82927.1| 351|Homo sapiens zinc binding alcohol
dehydrogenase protein.
Length = 351
Score = 68.1 bits (159), Expect = 2e-11
Identities = 33/64 (51%), Positives = 40/64 (62%), Gaps = 1/64 (1%)
Frame = +2
Query: 65 SLVGQIAKIKGC-RVIGFAGTDDKVKWLEEELGFDKAFNYKTVDVPAALKEAAPNGIDCY 241
S+ GQI GC RV+G GT +K L ELGFD A NYK +V L+E+ P G+D Y
Sbjct: 169 SVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVY 228
Query: 242 FDNV 253
FDNV
Sbjct: 229 FDNV 232
Score = 50.4 bits (115), Expect = 4e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Frame = +1
Query: 214 SCP*RDRLLFRQCRGEISSQIISKMNVYGRVSVCGSISAYNEDLT-KLPKATILQPSLVF 390
SCP + F G IS +IS+MN + +CG IS YN+D+ P + ++
Sbjct: 220 SCPAGVDVYFDNVGGNISDTVISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKE 279
Query: 391 NQIKVEGFLVWRWNAQ-SKAFAEIIPWIQSGKLKVKD 498
I E FLV + + ++ W + GKLK+K+
Sbjct: 280 RNITRERFLVLNYKDKFEPGILQLSQWFKEGKLKIKE 316
>AY346133-1|AAR05101.1| 351|Homo sapiens zinc binding alcohol
dehydrogenase domain containing 1 protein protein.
Length = 351
Score = 68.1 bits (159), Expect = 2e-11
Identities = 33/64 (51%), Positives = 40/64 (62%), Gaps = 1/64 (1%)
Frame = +2
Query: 65 SLVGQIAKIKGC-RVIGFAGTDDKVKWLEEELGFDKAFNYKTVDVPAALKEAAPNGIDCY 241
S+ GQI GC RV+G GT +K L ELGFD A NYK +V L+E+ P G+D Y
Sbjct: 169 SVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVY 228
Query: 242 FDNV 253
FDNV
Sbjct: 229 FDNV 232
Score = 50.4 bits (115), Expect = 4e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Frame = +1
Query: 214 SCP*RDRLLFRQCRGEISSQIISKMNVYGRVSVCGSISAYNEDLT-KLPKATILQPSLVF 390
SCP + F G IS +IS+MN + +CG IS YN+D+ P + ++
Sbjct: 220 SCPAGVDVYFDNVGGNISDTVISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKE 279
Query: 391 NQIKVEGFLVWRWNAQ-SKAFAEIIPWIQSGKLKVKD 498
I E FLV + + ++ W + GKLK+K+
Sbjct: 280 RNITRERFLVLNYKDKFEPGILQLSQWFKEGKLKIKE 316
>AK096410-1|BAC04781.1| 351|Homo sapiens protein ( Homo sapiens
cDNA FLJ39091 fis, clone NT2RP7019543, weakly similar to
NADP-DEPENDENT OXIDOREDUCTASE IN TEHB-RHSE INTERGENIC
REGION ).
Length = 351
Score = 68.1 bits (159), Expect = 2e-11
Identities = 33/64 (51%), Positives = 40/64 (62%), Gaps = 1/64 (1%)
Frame = +2
Query: 65 SLVGQIAKIKGC-RVIGFAGTDDKVKWLEEELGFDKAFNYKTVDVPAALKEAAPNGIDCY 241
S+ GQI GC RV+G GT +K L ELGFD A NYK +V L+E+ P G+D Y
Sbjct: 169 SVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAAINYKKDNVAEQLRESCPAGVDVY 228
Query: 242 FDNV 253
FDNV
Sbjct: 229 FDNV 232
Score = 50.4 bits (115), Expect = 4e-06
Identities = 30/97 (30%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Frame = +1
Query: 214 SCP*RDRLLFRQCRGEISSQIISKMNVYGRVSVCGSISAYNEDLT-KLPKATILQPSLVF 390
SCP + F G IS +IS+MN + +CG IS YN+D+ P + ++
Sbjct: 220 SCPAGVDVYFDNVGGNISDTVISQMNENSHIILCGQISQYNKDVPYPPPLSPAIEAIQKE 279
Query: 391 NQIKVEGFLVWRWNAQ-SKAFAEIIPWIQSGKLKVKD 498
I E FLV + + ++ W + GKLK+K+
Sbjct: 280 RNITRERFLVLNYKDKFEPGILQLSQWFKEGKLKIKE 316
>BC078661-1|AAH78661.1| 377|Homo sapiens zinc binding alcohol
dehydrogenase, domain containing 2 protein.
Length = 377
Score = 48.0 bits (109), Expect = 2e-05
Identities = 23/59 (38%), Positives = 35/59 (59%)
Frame = +2
Query: 77 QIAKIKGCRVIGFAGTDDKVKWLEEELGFDKAFNYKTVDVPAALKEAAPNGIDCYFDNV 253
Q++K C VIG +D+K +L+ LG D+ NYKT V LK+ P G+D +++V
Sbjct: 191 QLSKKAKCHVIGTCSSDEKSAFLKS-LGCDRPINYKTEPVGTVLKQEYPEGVDVVYESV 248
>BC033780-1|AAH33780.1| 377|Homo sapiens zinc binding alcohol
dehydrogenase, domain containing 2 protein.
Length = 377
Score = 48.0 bits (109), Expect = 2e-05
Identities = 23/59 (38%), Positives = 35/59 (59%)
Frame = +2
Query: 77 QIAKIKGCRVIGFAGTDDKVKWLEEELGFDKAFNYKTVDVPAALKEAAPNGIDCYFDNV 253
Q++K C VIG +D+K +L+ LG D+ NYKT V LK+ P G+D +++V
Sbjct: 191 QLSKKAKCHVIGTCSSDEKSAFLKS-LGCDRPINYKTEPVGTVLKQEYPEGVDVVYESV 248
>BC018081-1|AAH18081.1| 366|Homo sapiens ZADH2 protein protein.
Length = 366
Score = 47.2 bits (107), Expect = 4e-05
Identities = 23/59 (38%), Positives = 34/59 (57%)
Frame = +2
Query: 77 QIAKIKGCRVIGFAGTDDKVKWLEEELGFDKAFNYKTVDVPAALKEAAPNGIDCYFDNV 253
Q++K C VIG +D+K +L+ LG D NYKT V LK+ P G+D +++V
Sbjct: 191 QLSKKAKCHVIGTCSSDEKSAFLKS-LGCDSPINYKTEPVGTVLKQEYPEGVDVVYESV 248
>AK223201-1|BAD96921.1| 329|Homo sapiens crystallin, zeta variant
protein.
Length = 329
Score = 31.1 bits (67), Expect = 2.6
Identities = 19/61 (31%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +2
Query: 77 QIAKIKGCRVIGFAGTDDKVKWLEEELGFDKAFNYKTVD-VPAALKEAAPNGIDCYFDNV 253
QIA+ G +V+G AGT++ K + + G + FN++ V+ + K GID + +
Sbjct: 167 QIARAYGLKVLGTAGTEEGQKIVLQN-GAHEVFNHREVNYIDKIKKYVGEKGIDIIIEML 225
Query: 254 A 256
A
Sbjct: 226 A 226
>AK223150-1|BAD96870.1| 329|Homo sapiens crystallin, zeta variant
protein.
Length = 329
Score = 31.1 bits (67), Expect = 2.6
Identities = 19/61 (31%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +2
Query: 77 QIAKIKGCRVIGFAGTDDKVKWLEEELGFDKAFNYKTVD-VPAALKEAAPNGIDCYFDNV 253
QIA+ G +V+G AGT++ K + + G + FN++ V+ + K GID + +
Sbjct: 167 QIARAYGLKVLGTAGTEEGQKIVLQN-GAHEVFNHREVNYIDKIKKYVGEKGIDIIIEML 225
Query: 254 A 256
A
Sbjct: 226 A 226
>AB209714-1|BAD92951.1| 331|Homo sapiens crystallin, zeta variant
protein.
Length = 331
Score = 31.1 bits (67), Expect = 2.6
Identities = 19/61 (31%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +2
Query: 77 QIAKIKGCRVIGFAGTDDKVKWLEEELGFDKAFNYKTVD-VPAALKEAAPNGIDCYFDNV 253
QIA+ G +V+G AGT++ K + + G + FN++ V+ + K GID + +
Sbjct: 169 QIARAYGLKVLGTAGTEEGQKIVLQN-GAHEVFNHREVNYIDKIKKYVGEKGIDIIIEML 227
Query: 254 A 256
A
Sbjct: 228 A 228
>L31526-1|AAK40311.1| 329|Homo sapiens zeta-crystallin protein.
Length = 329
Score = 30.7 bits (66), Expect = 3.5
Identities = 18/61 (29%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +2
Query: 77 QIAKIKGCRVIGFAGTDDKVKWLEEELGFDKAFNYKTVD-VPAALKEAAPNGIDCYFDNV 253
QIA+ G +++G AGT++ K + + G + FN++ V+ + K GID + +
Sbjct: 167 QIARAYGLKILGTAGTEEGQKIVLQN-GAHEVFNHREVNYIDKIKKYVGEKGIDIIIEML 225
Query: 254 A 256
A
Sbjct: 226 A 226
>L13278-1|AAA36536.1| 329|Homo sapiens zeta-crystallin protein.
Length = 329
Score = 30.7 bits (66), Expect = 3.5
Identities = 18/61 (29%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +2
Query: 77 QIAKIKGCRVIGFAGTDDKVKWLEEELGFDKAFNYKTVD-VPAALKEAAPNGIDCYFDNV 253
QIA+ G +++G AGT++ K + + G + FN++ V+ + K GID + +
Sbjct: 167 QIARAYGLKILGTAGTEEGQKIVLQN-GAHEVFNHREVNYIDKIKKYVGEKGIDIIIEML 225
Query: 254 A 256
A
Sbjct: 226 A 226
>BC070058-1|AAH70058.1| 329|Homo sapiens CRYZ protein protein.
Length = 329
Score = 30.7 bits (66), Expect = 3.5
Identities = 18/61 (29%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +2
Query: 77 QIAKIKGCRVIGFAGTDDKVKWLEEELGFDKAFNYKTVD-VPAALKEAAPNGIDCYFDNV 253
QIA+ G +++G AGT++ K + + G + FN++ V+ + K GID + +
Sbjct: 167 QIARAYGLKILGTAGTEEGQKIVLQN-GAHEVFNHREVNYIDKIKKYVGEKGIDIIIEML 225
Query: 254 A 256
A
Sbjct: 226 A 226
>BC039578-1|AAH39578.1| 329|Homo sapiens crystallin, zeta (quinone
reductase) protein.
Length = 329
Score = 30.7 bits (66), Expect = 3.5
Identities = 18/61 (29%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +2
Query: 77 QIAKIKGCRVIGFAGTDDKVKWLEEELGFDKAFNYKTVD-VPAALKEAAPNGIDCYFDNV 253
QIA+ G +++G AGT++ K + + G + FN++ V+ + K GID + +
Sbjct: 167 QIARAYGLKILGTAGTEEGQKIVLQN-GAHEVFNHREVNYIDKIKKYVGEKGIDIIIEML 225
Query: 254 A 256
A
Sbjct: 226 A 226
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 70,992,950
Number of Sequences: 237096
Number of extensions: 1280406
Number of successful extensions: 3024
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 2918
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3006
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5364536570
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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