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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= heS00623X
         (595 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9NPE3 Cluster: H/ACA ribonucleoprotein complex subunit...    93   4e-18
UniRef50_Q9V5P6 Cluster: H/ACA ribonucleoprotein complex subunit...    89   1e-16
UniRef50_Q93XX8 Cluster: H/ACA ribonucleoprotein complex subunit...    82   8e-15
UniRef50_Q019V2 Cluster: H/ACA snoRNP complex, subunit NOP10; n=...    66   6e-10
UniRef50_UPI0000498FA1 Cluster: conserved hypothetical protein; ...    48   1e-04
UniRef50_A2EP66 Cluster: Nucleolar RNA-binding protein, putative...    46   9e-04
UniRef50_Q2FPD6 Cluster: Nucleolar RNA-binding protein Nop10p; n...    46   9e-04
UniRef50_A6UUW5 Cluster: Nucleolar RNA-binding protein Nop10p; n...    42   0.014
UniRef50_Q97Z78 Cluster: Ribosome biogenesis protein Nop10; n=2;...    41   0.025
UniRef50_Q8U1R4 Cluster: Ribosome biogenesis protein Nop10; n=7;...    36   0.54 
UniRef50_A0B683 Cluster: Nucleolar RNA-binding protein Nop10p; n...    36   0.95 
UniRef50_Q8TT00 Cluster: Ribosome biogenesis protein Nop10; n=7;...    36   0.95 
UniRef50_Q8ZTY6 Cluster: Ribosome biogenesis protein Nop10; n=4;...    35   1.3  
UniRef50_A0Q1X6 Cluster: Putative uncharacterized protein; n=1; ...    35   1.7  
UniRef50_Q05E71 Cluster: Small nucleolar RNP protein Nop10p; n=3...    35   1.7  
UniRef50_A4WE86 Cluster: Regulatory protein, IclR; n=6; Enteroba...    33   3.8  
UniRef50_Q8TY85 Cluster: Ribosome biogenesis protein Nop10; n=2;...    33   5.0  
UniRef50_Q9HAX1 Cluster: Desmocollin 3; n=2; Catarrhini|Rep: Des...    32   8.8  

>UniRef50_Q9NPE3 Cluster: H/ACA ribonucleoprotein complex subunit 3;
           n=25; Eukaryota|Rep: H/ACA ribonucleoprotein complex
           subunit 3 - Homo sapiens (Human)
          Length = 64

 Score = 93.1 bits (221), Expect = 4e-18
 Identities = 40/57 (70%), Positives = 48/57 (84%)
 Frame = +2

Query: 83  MYLRYYLNDKGDREYTLATIDPFGKPTLSAHPARFSPEDKYSRHRIIIKKRFGLLLT 253
           M+L+YYLN++GDR YTL   DP G+ T SAHPARFSP+DKYSRHRI IKKRF +L+T
Sbjct: 1   MFLQYYLNEQGDRVYTLKKFDPMGQQTCSAHPARFSPDDKYSRHRITIKKRFKVLMT 57


>UniRef50_Q9V5P6 Cluster: H/ACA ribonucleoprotein complex subunit 3;
           n=13; Eukaryota|Rep: H/ACA ribonucleoprotein complex
           subunit 3 - Drosophila melanogaster (Fruit fly)
          Length = 64

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 41/57 (71%), Positives = 45/57 (78%)
 Frame = +2

Query: 83  MYLRYYLNDKGDREYTLATIDPFGKPTLSAHPARFSPEDKYSRHRIIIKKRFGLLLT 253
           MYL Y +N+ GDR YTL      G+PTLSAHPARFSPEDKYSR R+ IKKRFGLLLT
Sbjct: 1   MYLMYTINENGDRVYTLKKRTEDGRPTLSAHPARFSPEDKYSRQRLTIKKRFGLLLT 57


>UniRef50_Q93XX8 Cluster: H/ACA ribonucleoprotein complex subunit
           3-like protein; n=35; Eukaryota|Rep: H/ACA
           ribonucleoprotein complex subunit 3-like protein -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 64

 Score = 82.2 bits (194), Expect = 8e-15
 Identities = 36/62 (58%), Positives = 46/62 (74%)
 Frame = +2

Query: 83  MYLRYYLNDKGDREYTLATIDPFGKPTLSAHPARFSPEDKYSRHRIIIKKRFGLLLTHNL 262
           MYL+ Y+N+KG++ YT     P G  T SAHPARFSP+DKYS+ R+++KKRFGLL T N 
Sbjct: 1   MYLQCYINEKGEKVYTTKKESPLGLATESAHPARFSPDDKYSKQRVLLKKRFGLLPTQNA 60

Query: 263 NL 268
            L
Sbjct: 61  PL 62


>UniRef50_Q019V2 Cluster: H/ACA snoRNP complex, subunit NOP10; n=2;
           Eukaryota|Rep: H/ACA snoRNP complex, subunit NOP10 -
           Ostreococcus tauri
          Length = 91

 Score = 66.1 bits (154), Expect = 6e-10
 Identities = 35/69 (50%), Positives = 43/69 (62%), Gaps = 13/69 (18%)
 Frame = +2

Query: 86  YLRYYLNDKGDREYTLATID-------------PFGKPTLSAHPARFSPEDKYSRHRIII 226
           YL YY ++KG+R YTL                 P G PT SAHPARFSP+DK+S+ R+ +
Sbjct: 16  YLMYYTDEKGERVYTLKVRSAKRRKPRAGDKTAPDGTPTHSAHPARFSPDDKFSKQRVAL 75

Query: 227 KKRFGLLLT 253
           KKRFGLL T
Sbjct: 76  KKRFGLLPT 84


>UniRef50_UPI0000498FA1 Cluster: conserved hypothetical protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 59

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 28/60 (46%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
 Frame = +2

Query: 89  LRYYLNDKGDREYTLATIDPFGKPTL-SAHPARFSPEDKYSRHRIIIKKRFGLLLTHNLN 265
           L YY ++   ++YT+ T  P     + SAHPA+FSP D YS++RI  KK FGLL T   N
Sbjct: 2   LLYYCDNC--KQYTMKTECPQCNGYVRSAHPAKFSPVDPYSKYRIATKKEFGLLPTSTKN 59


>UniRef50_A2EP66 Cluster: Nucleolar RNA-binding protein, putative;
           n=2; Trichomonas vaginalis G3|Rep: Nucleolar RNA-binding
           protein, putative - Trichomonas vaginalis G3
          Length = 83

 Score = 45.6 bits (103), Expect = 9e-04
 Identities = 25/44 (56%), Positives = 28/44 (63%), Gaps = 1/44 (2%)
 Frame = +2

Query: 119 REYTLATIDP-FGKPTLSAHPARFSPEDKYSRHRIIIKKRFGLL 247
           ++YTL    P  G  T SAHPARFSPEDK S  RI  K +F LL
Sbjct: 31  KQYTLKQKCPRCGGQTRSAHPARFSPEDKNSAERIQTKAKFNLL 74


>UniRef50_Q2FPD6 Cluster: Nucleolar RNA-binding protein Nop10p; n=1;
           Methanospirillum hungatei JF-1|Rep: Nucleolar
           RNA-binding protein Nop10p - Methanospirillum hungatei
           (strain JF-1 / DSM 864)
          Length = 49

 Score = 45.6 bits (103), Expect = 9e-04
 Identities = 19/39 (48%), Positives = 29/39 (74%), Gaps = 1/39 (2%)
 Frame = +2

Query: 116 DREYTLA-TIDPFGKPTLSAHPARFSPEDKYSRHRIIIK 229
           D  YTL+ T    GKPT++ HPAR+SP+D+Y ++R +I+
Sbjct: 11  DNLYTLSETCSSCGKPTITPHPARYSPDDRYGKYRRMIR 49


>UniRef50_A6UUW5 Cluster: Nucleolar RNA-binding protein Nop10p; n=1;
           Methanococcus aeolicus Nankai-3|Rep: Nucleolar
           RNA-binding protein Nop10p - Methanococcus aeolicus
           Nankai-3
          Length = 51

 Score = 41.5 bits (93), Expect = 0.014
 Identities = 17/38 (44%), Positives = 26/38 (68%)
 Frame = +2

Query: 119 REYTLATIDPFGKPTLSAHPARFSPEDKYSRHRIIIKK 232
           + YTL TI   G+ T++  P R+SP DKY ++R ++KK
Sbjct: 10  KNYTLNTICQCGEKTITVKPPRYSPTDKYGKYRRMLKK 47


>UniRef50_Q97Z78 Cluster: Ribosome biogenesis protein Nop10; n=2;
           Sulfolobus|Rep: Ribosome biogenesis protein Nop10 -
           Sulfolobus solfataricus
          Length = 56

 Score = 40.7 bits (91), Expect = 0.025
 Identities = 20/40 (50%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
 Frame = +2

Query: 116 DREYTLA-TIDPFGKPTLSAHPARFSPEDKYSRHRIIIKK 232
           D  YT   T    G  T+  HP+RFSPEDKY ++RI +KK
Sbjct: 11  DNIYTFKDTCQICGSKTVIPHPSRFSPEDKYVKYRIELKK 50


>UniRef50_Q8U1R4 Cluster: Ribosome biogenesis protein Nop10; n=7;
           Archaea|Rep: Ribosome biogenesis protein Nop10 -
           Pyrococcus furiosus
          Length = 60

 Score = 36.3 bits (80), Expect = 0.54
 Identities = 17/32 (53%), Positives = 20/32 (62%), Gaps = 1/32 (3%)
 Frame = +2

Query: 125 YTLATIDPF-GKPTLSAHPARFSPEDKYSRHR 217
           YTL  + P  G+ T  AHP RFSPED Y  +R
Sbjct: 14  YTLKEVCPVCGEKTKVAHPPRFSPEDPYGEYR 45


>UniRef50_A0B683 Cluster: Nucleolar RNA-binding protein Nop10p; n=1;
           Methanosaeta thermophila PT|Rep: Nucleolar RNA-binding
           protein Nop10p - Methanosaeta thermophila (strain DSM
           6194 / PT) (Methanothrixthermophila (strain DSM 6194 /
           PT))
          Length = 60

 Score = 35.5 bits (78), Expect = 0.95
 Identities = 18/34 (52%), Positives = 20/34 (58%), Gaps = 1/34 (2%)
 Frame = +2

Query: 119 REYTLATIDP-FGKPTLSAHPARFSPEDKYSRHR 217
           R YTL    P  G  T    PARFSPED+Y R+R
Sbjct: 13  RLYTLKETCPRCGSHTTGTKPARFSPEDRYGRYR 46


>UniRef50_Q8TT00 Cluster: Ribosome biogenesis protein Nop10; n=7;
           Euryarchaeota|Rep: Ribosome biogenesis protein Nop10 -
           Methanosarcina acetivorans
          Length = 51

 Score = 35.5 bits (78), Expect = 0.95
 Identities = 19/37 (51%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
 Frame = +2

Query: 125 YTLATIDPF-GKPTLSAHPARFSPEDKYSRHRIIIKK 232
           YTL    P  G  TL A PARFSP+D Y ++R + KK
Sbjct: 14  YTLREKCPVCGGVTLPAIPARFSPQDPYGKYRRLAKK 50


>UniRef50_Q8ZTY6 Cluster: Ribosome biogenesis protein Nop10; n=4;
           Archaea|Rep: Ribosome biogenesis protein Nop10 -
           Pyrobaculum aerophilum
          Length = 72

 Score = 35.1 bits (77), Expect = 1.3
 Identities = 14/25 (56%), Positives = 18/25 (72%)
 Frame = +2

Query: 173 HPARFSPEDKYSRHRIIIKKRFGLL 247
           HP +FSPEDKY ++RI+ K   G L
Sbjct: 32  HPPKFSPEDKYQKYRILQKLLMGKL 56


>UniRef50_A0Q1X6 Cluster: Putative uncharacterized protein; n=1;
           Clostridium novyi NT|Rep: Putative uncharacterized
           protein - Clostridium novyi (strain NT)
          Length = 161

 Score = 34.7 bits (76), Expect = 1.7
 Identities = 14/37 (37%), Positives = 24/37 (64%)
 Frame = -2

Query: 405 FVRAFVFCCMLYKSCVP*ILKIIVKMYQNLDHFGNFQ 295
           ++ AF+   +  KSC P I ++IV++  NLD + NF+
Sbjct: 86  YMEAFMNYSLNIKSCYPNIYRVIVRLLMNLDKYENFE 122


>UniRef50_Q05E71 Cluster: Small nucleolar RNP protein Nop10p; n=3;
           Desulfurococcaceae|Rep: Small nucleolar RNP protein
           Nop10p - Aeropyrum pernix
          Length = 58

 Score = 34.7 bits (76), Expect = 1.7
 Identities = 12/32 (37%), Positives = 22/32 (68%)
 Frame = +2

Query: 152 GKPTLSAHPARFSPEDKYSRHRIIIKKRFGLL 247
           G P    HP RFSP++++ ++R  ++K+ GL+
Sbjct: 25  GGPVAVPHPPRFSPDNRFIKYRYELQKKLGLI 56


>UniRef50_A4WE86 Cluster: Regulatory protein, IclR; n=6;
           Enterobacteriaceae|Rep: Regulatory protein, IclR -
           Enterobacter sp. 638
          Length = 253

 Score = 33.5 bits (73), Expect = 3.8
 Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 1/43 (2%)
 Frame = -2

Query: 291 KSIFILMNRFRLCVSSRPNLFLII-ILCLEYLSSGEKRAGCAD 166
           +S   L+ R  + +SS+PN  LI  I CL+YL S ++  GC +
Sbjct: 11  ESSHTLLKRMSVAMSSQPNQSLIDGIRCLQYLVSSDRAIGCRE 53


>UniRef50_Q8TY85 Cluster: Ribosome biogenesis protein Nop10; n=2;
           Euryarchaeota|Rep: Ribosome biogenesis protein Nop10 -
           Methanopyrus kandleri
          Length = 66

 Score = 33.1 bits (72), Expect = 5.0
 Identities = 13/21 (61%), Positives = 16/21 (76%)
 Frame = +2

Query: 173 HPARFSPEDKYSRHRIIIKKR 235
           HP RFSPED Y ++R  +KKR
Sbjct: 32  HPHRFSPEDPYGKYRRKLKKR 52


>UniRef50_Q9HAX1 Cluster: Desmocollin 3; n=2; Catarrhini|Rep:
           Desmocollin 3 - Homo sapiens (Human)
          Length = 316

 Score = 32.3 bits (70), Expect = 8.8
 Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
 Frame = -2

Query: 555 HHDLE*CQGARSNVDNCKGPMYQWGRLRLPQ-SDKNH 448
           HH L+ C+G  + VDNC+    +W     P+  +K H
Sbjct: 218 HHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEKLH 254


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 549,722,931
Number of Sequences: 1657284
Number of extensions: 10515105
Number of successful extensions: 19738
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 19268
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 19737
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 41488046300
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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