Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= heS00575
(764 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9NR45 Cluster: Sialic acid synthase; n=39; Coelomata|R... 107 4e-22
UniRef50_UPI0000D9DE3E Cluster: PREDICTED: similar to N-acetylne... 105 9e-22
UniRef50_Q9VG74 Cluster: CG5232-PA; n=4; Diptera|Rep: CG5232-PA ... 86 8e-16
UniRef50_A6D0F9 Cluster: Sialic acid synthase; n=2; Gammaproteob... 74 4e-12
UniRef50_Q9RDX5 Cluster: N-acetylneuraminic acid condensing enzy... 73 1e-11
UniRef50_A6L7H8 Cluster: Sialic acid synthase; n=1; Bacteroides ... 73 1e-11
UniRef50_Q04TT0 Cluster: N-acetyl neuraminic (Sialic) acid synth... 67 4e-10
UniRef50_A0NMM3 Cluster: N-acylneuraminate-9-phosphate synthase;... 66 1e-09
UniRef50_Q9A4G6 Cluster: NeuB protein, putative; n=17; Bacteria|... 64 3e-09
UniRef50_A4FX91 Cluster: N-acylneuraminate-9-phosphate synthase;... 64 3e-09
UniRef50_Q74B32 Cluster: Polysaccharide biosynthesis protein, pu... 63 6e-09
UniRef50_A4MIF1 Cluster: N-acylneuraminate-9-phosphate synthase;... 62 1e-08
UniRef50_Q8A711 Cluster: Sialic acid synthase; n=1; Bacteroides ... 62 2e-08
UniRef50_A7GGU3 Cluster: NeuB family protein; n=1; Clostridium b... 60 6e-08
UniRef50_UPI00015B984F Cluster: UPI00015B984F related cluster; n... 59 1e-07
UniRef50_Q73P39 Cluster: NeuB family protein; n=1; Treponema den... 59 1e-07
UniRef50_Q5R082 Cluster: Sialic acid synthase; n=47; Bacteria|Re... 59 1e-07
UniRef50_Q0FYM0 Cluster: N-acylneuraminate-9-phosphate synthase;... 59 1e-07
UniRef50_Q2Y4J1 Cluster: NeuB family member; n=5; cellular organ... 59 1e-07
UniRef50_Q58465 Cluster: Uncharacterized protein MJ1065; n=1; Me... 58 2e-07
UniRef50_Q07IS3 Cluster: N-acetylneuraminate synthase; n=1; Rhod... 58 2e-07
UniRef50_A4B2T9 Cluster: NeuB:Antifreeze-like protein; n=1; Alte... 58 3e-07
UniRef50_Q97H26 Cluster: Sialic acid synthase; n=14; cellular or... 57 6e-07
UniRef50_A7DQW3 Cluster: N-acylneuraminate-9-phosphate synthase;... 56 7e-07
UniRef50_A3V3D1 Cluster: Polysialic acid capsule biosynthesis pr... 56 1e-06
UniRef50_Q3XXA4 Cluster: N-acetylneuraminate synthase; n=1; Ente... 56 1e-06
UniRef50_Q12JI6 Cluster: N-acetylneuraminic acid synthase-like p... 56 1e-06
UniRef50_Q8TJL5 Cluster: N-acetylneuraminic acid phosphate synth... 56 1e-06
UniRef50_A4U173 Cluster: NeuB; n=1; Magnetospirillum gryphiswald... 55 2e-06
UniRef50_Q46675 Cluster: NeuB protein; n=8; Bacteria|Rep: NeuB p... 54 3e-06
UniRef50_Q2N2P7 Cluster: NeuB; n=7; Proteobacteria|Rep: NeuB - A... 54 3e-06
UniRef50_Q7VHQ5 Cluster: Sialic acid synthase; n=6; Helicobacter... 54 4e-06
UniRef50_Q1PVV9 Cluster: Similarity to N-acetyl neuramic acid sy... 54 4e-06
UniRef50_Q04TM5 Cluster: N-acetylneuraminic acid (Sialic acid) s... 53 7e-06
UniRef50_P39625 Cluster: Spore coat polysaccharide biosynthesis ... 52 1e-05
UniRef50_Q0A628 Cluster: N-acylneuraminate-9-phosphate synthase;... 52 2e-05
UniRef50_Q0M1E8 Cluster: N-acylneuraminate-9-phosphate synthase;... 51 3e-05
UniRef50_Q0IDR1 Cluster: N-acetylneuraminic acid condensing enzy... 51 3e-05
UniRef50_Q3AZQ1 Cluster: N-acylneuraminate-9-phosphate synthase;... 50 5e-05
UniRef50_A5MZ25 Cluster: Predicted polysaccharide biosynthesis p... 50 5e-05
UniRef50_Q1IMQ8 Cluster: N-acetylneuraminate synthase; n=16; Bac... 50 8e-05
UniRef50_A3Y8V9 Cluster: NeuB family protein; n=1; Marinomonas s... 50 8e-05
UniRef50_Q893U6 Cluster: N-acetylneuraminate synthase; n=1; Clos... 49 1e-04
UniRef50_Q4VKA5 Cluster: NeuNAc condensing enzyme; n=54; cellula... 48 2e-04
UniRef50_A2C5V5 Cluster: Sialic acid synthase; n=1; Prochlorococ... 48 3e-04
UniRef50_A1WSD6 Cluster: N-acylneuraminate-9-phosphate synthase;... 48 3e-04
UniRef50_Q726U8 Cluster: NeuB family protein; n=2; Desulfovibrio... 48 3e-04
UniRef50_A4AP54 Cluster: N-acetylneuraminate synthase; n=3; cell... 48 3e-04
UniRef50_Q93NQ2 Cluster: NnaB; n=7; Bacteria|Rep: NnaB - Escheri... 45 0.002
UniRef50_Q89HJ8 Cluster: Blr5992 protein; n=2; Proteobacteria|Re... 45 0.002
UniRef50_A3PE56 Cluster: Sialic acid synthase; n=1; Prochlorococ... 45 0.002
UniRef50_Q11RF6 Cluster: N-acetylneuraminic acid synthetase; n=2... 44 0.003
UniRef50_Q04TP3 Cluster: N-acetylneuraminic acid (Sialic acid) s... 44 0.003
UniRef50_A6W187 Cluster: N-acylneuraminate-9-phosphate synthase;... 44 0.004
UniRef50_A0LYV7 Cluster: N-acetylneuraminate synthase; n=1; Gram... 44 0.004
UniRef50_A5W0I0 Cluster: N-acetylneuraminic acid synthase, N-ter... 44 0.005
UniRef50_Q8EC83 Cluster: Polysaccharide biosynthesis related-pro... 43 0.007
UniRef50_Q8DDZ7 Cluster: Sialic acid synthase; n=5; Bacteria|Rep... 43 0.007
UniRef50_O83573 Cluster: Spore coat polysaccharide biosynthesis ... 43 0.007
UniRef50_Q0P8U0 Cluster: Pse synthetase; n=14; Campylobacter|Rep... 42 0.013
UniRef50_UPI0000384B44 Cluster: COG2089: Sialic acid synthase; n... 42 0.017
UniRef50_Q2BJD7 Cluster: N-acetylneuraminic acid synthetase; n=1... 41 0.029
UniRef50_Q30V22 Cluster: N-acylneuraminate-9-phosphate synthase;... 41 0.039
UniRef50_A1RHT0 Cluster: N-acylneuraminate-9-phosphate synthase;... 40 0.051
UniRef50_A0LAB4 Cluster: N-acetylneuraminic acid synthase, N-ter... 40 0.068
UniRef50_Q18EL3 Cluster: Sialic acid synthase; n=1; Haloquadratu... 40 0.068
UniRef50_Q5QWT8 Cluster: Sialic acid synthase; n=14; Bacteria|Re... 30 0.096
UniRef50_Q1GST3 Cluster: N-acylneuraminate-9-phosphate synthase;... 39 0.12
UniRef50_Q89HL9 Cluster: Blr5971 protein; n=1; Bradyrhizobium ja... 39 0.16
UniRef50_A7DQU2 Cluster: N-acylneuraminate-9-phosphate synthase;... 38 0.21
UniRef50_Q319P5 Cluster: Putative spore coat polysaccharide bios... 38 0.27
UniRef50_A2BSE7 Cluster: Sialic acid synthase; n=1; Prochlorococ... 38 0.27
UniRef50_Q0YTS4 Cluster: N-acylneuraminate-9-phosphate synthase;... 36 0.83
UniRef50_Q0AN71 Cluster: N-acetylneuraminate synthase; n=1; Mari... 35 1.9
UniRef50_Q5A950 Cluster: Sterol 3-beta-glucosyltransferase; n=2;... 34 4.4
UniRef50_Q2IZW6 Cluster: N-acetylneuraminate synthase; n=1; Rhod... 33 5.9
UniRef50_A4U183 Cluster: N-acetylneuraminate synthase; n=1; Magn... 33 7.8
>UniRef50_Q9NR45 Cluster: Sialic acid synthase; n=39; Coelomata|Rep:
Sialic acid synthase - Homo sapiens (Human)
Length = 359
Score = 107 bits (256), Expect = 4e-22
Identities = 49/69 (71%), Positives = 54/69 (78%)
Frame = +1
Query: 298 GASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVG 477
GA C KFQK+ L KF +K LERPY + +SWGKTYGEHK HLEFS QYREL RYA+EVG
Sbjct: 47 GADCAKFQKSELEFKFNRKALERPYTSKHSWGKTYGEHKRHLEFSHDQYRELQRYAEEVG 106
Query: 478 ILFTASAMD 504
I FTAS MD
Sbjct: 107 IFFTASGMD 115
Score = 81.0 bits (191), Expect = 3e-14
Identities = 36/81 (44%), Positives = 51/81 (62%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQF 695
+FL L VPF ++GSGD+NN +L+ A K P++IS+GM +K +Y I+ + F
Sbjct: 120 EFLHELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVYQIVKPLNPNF 179
Query: 696 CLLHCISAYPVPFEDCNLTVL 758
C L C SAYP+ ED NL V+
Sbjct: 180 CFLQCTSAYPLQPEDVNLRVI 200
Score = 40.7 bits (91), Expect = 0.039
Identities = 16/29 (55%), Positives = 22/29 (75%)
Frame = +2
Query: 167 VEVKITDDIRIGGNNPCFIIAEAGQNHQG 253
+E+++ +GG +PCFIIAE GQNHQG
Sbjct: 3 LELELCPGRWVGGQHPCFIIAEIGQNHQG 31
>UniRef50_UPI0000D9DE3E Cluster: PREDICTED: similar to
N-acetylneuraminic acid phosphate synthase; n=1; Macaca
mulatta|Rep: PREDICTED: similar to N-acetylneuraminic
acid phosphate synthase - Macaca mulatta
Length = 274
Score = 105 bits (253), Expect = 9e-22
Identities = 48/69 (69%), Positives = 54/69 (78%)
Frame = +1
Query: 298 GASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVG 477
GA C KFQK+ L KF +K LERPY + +SWGKTYGEHK HLEF+ QYREL RYA+EVG
Sbjct: 47 GADCAKFQKSELEFKFNRKALERPYTSKHSWGKTYGEHKRHLEFNHDQYRELQRYAEEVG 106
Query: 478 ILFTASAMD 504
I FTAS MD
Sbjct: 107 IFFTASGMD 115
Score = 40.7 bits (91), Expect = 0.039
Identities = 16/29 (55%), Positives = 22/29 (75%)
Frame = +2
Query: 167 VEVKITDDIRIGGNNPCFIIAEAGQNHQG 253
+E+++ +GG +PCFIIAE GQNHQG
Sbjct: 3 LELELCPGRWVGGQHPCFIIAEIGQNHQG 31
>UniRef50_Q9VG74 Cluster: CG5232-PA; n=4; Diptera|Rep: CG5232-PA -
Drosophila melanogaster (Fruit fly)
Length = 372
Score = 86.2 bits (204), Expect = 8e-16
Identities = 40/75 (53%), Positives = 52/75 (69%)
Frame = +1
Query: 298 GASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVG 477
G CVKFQK+ L KFT+ L+R Y + ++WGKTYGEHK +LEFS QY +L + +E+
Sbjct: 43 GCHCVKFQKSDLPAKFTRSALDREYISDHAWGKTYGEHKEYLEFSKDQYLQLQAHCKELN 102
Query: 478 ILFTASAMDMDLLTF 522
+ FTASAMD L F
Sbjct: 103 VDFTASAMDERSLEF 117
Score = 80.2 bits (189), Expect = 5e-14
Identities = 38/84 (45%), Positives = 55/84 (65%), Gaps = 1/84 (1%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK 689
S +FL L VPFI+IGSGD+NN LK AA+ +PL+ISTGM V+ I + K
Sbjct: 114 SLEFLSALNVPFIKIGSGDANNFPLLKKAANLNLPLVISTGMQTMQTVERIVQTMRESGK 173
Query: 690 Q-FCLLHCISAYPVPFEDCNLTVL 758
+ + L+HC+S+YP +DC+L ++
Sbjct: 174 EDYALMHCVSSYPTDPKDCSLQLI 197
>UniRef50_A6D0F9 Cluster: Sialic acid synthase; n=2;
Gammaproteobacteria|Rep: Sialic acid synthase - Vibrio
shilonii AK1
Length = 751
Score = 73.7 bits (173), Expect = 4e-12
Identities = 35/84 (41%), Positives = 50/84 (59%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK 689
S D L + V ++ S D N LKY A+KK+PLI+STGM + + + +++ +
Sbjct: 228 SADKLEKIGVAGFKVASADLTNHRLLKYLAAKKVPLILSTGMSVEQEIISAVELLEKESA 287
Query: 690 QFCLLHCISAYPVPFEDCNLTVLQ 761
F LLHC S YP PF+D NLT L+
Sbjct: 288 SFALLHCNSTYPAPFKDVNLTYLK 311
>UniRef50_Q9RDX5 Cluster: N-acetylneuraminic acid condensing enzyme;
n=6; Bacteria|Rep: N-acetylneuraminic acid condensing
enzyme - Legionella pneumophila
Length = 338
Score = 72.5 bits (170), Expect = 1e-11
Identities = 38/89 (42%), Positives = 54/89 (60%), Gaps = 5/89 (5%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDII----- 674
S DFL++L V ++I SG+ N+ +L++ ASKK+PLIISTGM D V+ D +
Sbjct: 103 SIDFLISLGVKRLKIPSGEITNVPYLQHCASKKLPLIISTGMCDLQEVRVAIDTVKPYYG 162
Query: 675 SSDHKQFCLLHCISAYPVPFEDCNLTVLQ 761
+S LLHC S YP ++D NL +Q
Sbjct: 163 NSLSDYLVLLHCTSNYPASYQDVNLKAMQ 191
>UniRef50_A6L7H8 Cluster: Sialic acid synthase; n=1; Bacteroides
vulgatus ATCC 8482|Rep: Sialic acid synthase -
Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC
11154)
Length = 334
Score = 72.5 bits (170), Expect = 1e-11
Identities = 35/85 (41%), Positives = 50/85 (58%), Gaps = 1/85 (1%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIY-DIISSDH 686
S DFL N +PFI++GSGD N+ FL+ S+ I +++STGM V+ Y +I +
Sbjct: 106 SLDFLCNFNLPFIKLGSGDVTNIPFLRLVGSRHIDVVLSTGMSYLGDVEIAYRTLIEAGA 165
Query: 687 KQFCLLHCISAYPVPFEDCNLTVLQ 761
K LLHC + YP P + NL +Q
Sbjct: 166 KSVSLLHCTTNYPCPMHEVNLRAIQ 190
>UniRef50_Q04TT0 Cluster: N-acetyl neuraminic (Sialic) acid
synthetase; n=4; Leptospira|Rep: N-acetyl neuraminic
(Sialic) acid synthetase - Leptospira borgpetersenii
serovar Hardjo-bovis (strain JB197)
Length = 332
Score = 67.3 bits (157), Expect = 4e-10
Identities = 34/85 (40%), Positives = 47/85 (55%), Gaps = 1/85 (1%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-H 686
S L++LKVP I+I SGD N L A K+P+I+S+G D V + +
Sbjct: 111 SLHLLLSLKVPAIKIASGDITNKTLLLETAKSKLPVILSSGAADFFEVNRAISFLEKEGT 170
Query: 687 KQFCLLHCISAYPVPFEDCNLTVLQ 761
+ CLLHC+S YP P E NL V++
Sbjct: 171 DKLCLLHCVSLYPTPPEKANLKVVE 195
>UniRef50_A0NMM3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Stappia aggregata IAM 12614|Rep:
N-acylneuraminate-9-phosphate synthase - Stappia
aggregata IAM 12614
Length = 287
Score = 65.7 bits (153), Expect = 1e-09
Identities = 33/82 (40%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
Frame = +3
Query: 507 GSFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIIS-SD 683
GS DFL++ P+I++ S + FL+Y A PL++STGM D VK+ D+I S
Sbjct: 103 GSVDFLLDYDTPYIKVASAMVTDRDFLEYCARSGRPLLVSTGMSDMAMVKSFVDVIERSG 162
Query: 684 HKQFCLLHCISAYPVPFEDCNL 749
+ CL HC S YP ++ NL
Sbjct: 163 GEIACLYHCTSTYPTRDDEINL 184
Score = 42.3 bits (95), Expect = 0.013
Identities = 26/77 (33%), Positives = 39/77 (50%)
Frame = +1
Query: 298 GASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVG 477
G VKFQK + ++ + L RP +N +G T G+ K LEF Y + + +E+G
Sbjct: 35 GCDAVKFQKRTVDVVYSAEELARPRENV--FGTTNGDLKRGLEFGKADYDRIDKLCKELG 92
Query: 478 ILFTASAMDMDLLTFWL 528
I + AS D + F L
Sbjct: 93 IDWFASPWDEGSVDFLL 109
>UniRef50_Q9A4G6 Cluster: NeuB protein, putative; n=17;
Bacteria|Rep: NeuB protein, putative - Caulobacter
crescentus (Caulobacter vibrioides)
Length = 356
Score = 64.5 bits (150), Expect = 3e-09
Identities = 34/79 (43%), Positives = 49/79 (62%), Gaps = 1/79 (1%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYD-IISSDHKQ 692
D L +L P +I S ++ +L +KYAA+K PLIISTGM + T ++T D +S+
Sbjct: 127 DLLDSLGAPAFKIASFEAVDLPLIKYAAAKGKPLIISTGMANLTEMQTALDTALSAGAPG 186
Query: 693 FCLLHCISAYPVPFEDCNL 749
LLHC+S+YP F D N+
Sbjct: 187 VLLLHCVSSYPATFADANV 205
>UniRef50_A4FX91 Cluster: N-acylneuraminate-9-phosphate synthase;
n=5; cellular organisms|Rep:
N-acylneuraminate-9-phosphate synthase - Methanococcus
maripaludis
Length = 348
Score = 64.5 bits (150), Expect = 3e-09
Identities = 35/84 (41%), Positives = 52/84 (61%), Gaps = 1/84 (1%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDH 686
S DFL +L VP +I S D NN+ FLK+ A KK P+IISTGM + + + + ++ +
Sbjct: 116 SADFLDDL-VPLFKISSTDLNNIPFLKHIAKKKKPVIISTGMGTLCEIEEAVTALKNAGN 174
Query: 687 KQFCLLHCISAYPVPFEDCNLTVL 758
+ LLHC+++YP E NL V+
Sbjct: 175 HEIMLLHCVTSYPAKDESLNLNVI 198
Score = 35.9 bits (79), Expect = 1.1
Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 2/77 (2%)
Frame = +1
Query: 298 GASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTYGEHK--SHLEFSDTQYRELFRYAQE 471
G VKFQ T+ + Y N+ ++ +++ LE S+ + L+ Y QE
Sbjct: 43 GVDAVKFQTFKTENVVTENAEKAEYQIQNTGVESESQYEMIKKLELSEKDFERLYNYCQE 102
Query: 472 VGILFTASAMDMDLLTF 522
GILF ++ D + F
Sbjct: 103 KGILFLSTPFDFESADF 119
>UniRef50_Q74B32 Cluster: Polysaccharide biosynthesis protein,
putative; n=1; Geobacter sulfurreducens|Rep:
Polysaccharide biosynthesis protein, putative -
Geobacter sulfurreducens
Length = 350
Score = 63.3 bits (147), Expect = 6e-09
Identities = 31/79 (39%), Positives = 48/79 (60%), Gaps = 1/79 (1%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-HKQ 692
D L +L VPF +I S D +L FLKY A K+ P+++STGM ++ + + ++ + Q
Sbjct: 120 DLLESLDVPFFKIASMDIVHLPFLKYVARKRRPMLLSTGMATLAEIEAAVETVRAEGNDQ 179
Query: 693 FCLLHCISAYPVPFEDCNL 749
LLHC+S YP +E +L
Sbjct: 180 VVLLHCVSIYPPDYEMIHL 198
>UniRef50_A4MIF1 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Geobacter bemidjiensis Bem|Rep:
N-acylneuraminate-9-phosphate synthase - Geobacter
bemidjiensis Bem
Length = 338
Score = 62.5 bits (145), Expect = 1e-08
Identities = 36/103 (34%), Positives = 56/103 (54%), Gaps = 1/103 (0%)
Frame = +3
Query: 459 IRSGGRDFIHRLCHGHGSFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMV 638
IR+ G D+ H D L L V +IGS D+ N+ FL+Y A+K P++++TGM
Sbjct: 90 IRAKGLDWFSTPSH-EADVDLLDRLGVSAYKIGSDDAVNIPFLRYVAAKGKPVLLATGMC 148
Query: 639 DKTAVKTIYDII-SSDHKQFCLLHCISAYPVPFEDCNLTVLQA 764
V+ D+I + + + LLH +++YP E NL +QA
Sbjct: 149 TMQEVRESVDVILGAGNLELILLHAVTSYPTHPEHVNLLAMQA 191
>UniRef50_Q8A711 Cluster: Sialic acid synthase; n=1; Bacteroides
thetaiotaomicron|Rep: Sialic acid synthase - Bacteroides
thetaiotaomicron
Length = 346
Score = 61.7 bits (143), Expect = 2e-08
Identities = 33/99 (33%), Positives = 48/99 (48%)
Frame = +3
Query: 462 RSGGRDFIHRLCHGHGSFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVD 641
+S G DFI LC G L +++ S D NL L+ A IP+I+STGM
Sbjct: 99 KSLGLDFIETLC-AKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAG 157
Query: 642 KTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNLTVL 758
+ + D+I+ H +LHC+S YP + NL +
Sbjct: 158 QRELDNALDVITRYHSNIAILHCVSQYPTHPNNLNLRTI 196
Score = 61.3 bits (142), Expect = 3e-08
Identities = 25/61 (40%), Positives = 40/61 (65%)
Frame = +1
Query: 304 SCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGIL 483
+ VK K L E+ + + YDNPNS+G+TYGEH++ LE D + E+++YA+ +G+
Sbjct: 45 NAVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD 104
Query: 484 F 486
F
Sbjct: 105 F 105
>UniRef50_A7GGU3 Cluster: NeuB family protein; n=1; Clostridium
botulinum F str. Langeland|Rep: NeuB family protein -
Clostridium botulinum (strain Langeland / NCTC 10281 /
Type F)
Length = 343
Score = 60.1 bits (139), Expect = 6e-08
Identities = 33/85 (38%), Positives = 50/85 (58%), Gaps = 1/85 (1%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDH 686
S D ++NL I++ SG+ ++ F+K AAS PLIISTG + + V + + I S
Sbjct: 105 SLDDIINLDCSAIKVASGELTHIPFIKKAASYNKPLIISTGASNLSDVERAVIAIKSVAD 164
Query: 687 KQFCLLHCISAYPVPFEDCNLTVLQ 761
++ +LHC+S YP P E NL L+
Sbjct: 165 EKISILHCVSTYPSPDECLNLRALK 189
>UniRef50_UPI00015B984F Cluster: UPI00015B984F related cluster; n=1;
unknown|Rep: UPI00015B984F UniRef100 entry - unknown
Length = 361
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/84 (35%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVK-TIYDIISSDH 686
S DFL L VP ++ SGD N L+ A+K P+IISTGM + ++ + + ++
Sbjct: 129 SVDFLATLGVPAYKVSSGDLTNHFLLEAVAAKGKPVIISTGMANLADIEGALACLRTAGA 188
Query: 687 KQFCLLHCISAYPVPFEDCNLTVL 758
++ C L C S+YP P + NL +
Sbjct: 189 REVCALQCTSSYPAPPDQINLRTI 212
>UniRef50_Q73P39 Cluster: NeuB family protein; n=1; Treponema
denticola|Rep: NeuB family protein - Treponema denticola
Length = 379
Score = 58.8 bits (136), Expect = 1e-07
Identities = 31/89 (34%), Positives = 52/89 (58%), Gaps = 2/89 (2%)
Frame = +3
Query: 501 GHGSFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISS 680
G S + L LK FI+I S + N + LKY A IP+I+S+G+ ++ + S
Sbjct: 113 GFRSAEELAALKPDFIKIASPELNYVQLLKYCAGFNIPMILSSGVSILKDIEKAVSFLRS 172
Query: 681 DHKQ--FCLLHCISAYPVPFEDCNLTVLQ 761
++K LLHCI++YP P ++ N++V++
Sbjct: 173 ENKDLPLALLHCITSYPAPEKEYNVSVIK 201
>UniRef50_Q5R082 Cluster: Sialic acid synthase; n=47; Bacteria|Rep:
Sialic acid synthase - Idiomarina loihiensis
Length = 352
Score = 58.8 bits (136), Expect = 1e-07
Identities = 29/70 (41%), Positives = 39/70 (55%)
Frame = +3
Query: 522 LVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCL 701
L + V +IGSG+ NN L+ AS K P+I+STGM D ++ DI Q+ L
Sbjct: 124 LERMGVEAYKIGSGECNNYPLLELVASYKKPIILSTGMNDIPSIAKAVDIFRKHGVQYAL 183
Query: 702 LHCISAYPVP 731
LHC + YP P
Sbjct: 184 LHCTNVYPTP 193
>UniRef50_Q0FYM0 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Fulvimarina pelagi HTCC2506|Rep:
N-acylneuraminate-9-phosphate synthase - Fulvimarina
pelagi HTCC2506
Length = 347
Score = 58.8 bits (136), Expect = 1e-07
Identities = 32/84 (38%), Positives = 46/84 (54%), Gaps = 1/84 (1%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDII-SSDH 686
S DFL +L V +I SGD +L FL++ A K P+IISTGM + ++ D I ++
Sbjct: 115 SADFLESLGVEAFKISSGDLTHLAFLQHVARKGRPMIISTGMANLADIEEAVDAIEAAGS 174
Query: 687 KQFCLLHCISAYPVPFEDCNLTVL 758
+LHC+S YP NL +
Sbjct: 175 PPLAILHCVSDYPADPASSNLMAI 198
>UniRef50_Q2Y4J1 Cluster: NeuB family member; n=5; cellular
organisms|Rep: NeuB family member - uncultured archaeon
Length = 360
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/83 (36%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-HKQ 692
DFL L +P +I S D N+ F+ Y A K+ P+ +STG +K + I S+ + +
Sbjct: 127 DFLDKL-MPVFKISSSDITNIPFISYVARKRKPIFLSTGASTIEEIKEAVNAIESEGNDK 185
Query: 693 FCLLHCISAYPVPFEDCNLTVLQ 761
+LHCI YP +ED NL +++
Sbjct: 186 IVILHCILNYPTKYEDANLGMIK 208
Score = 37.5 bits (83), Expect = 0.36
Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Frame = +1
Query: 298 GASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKT-YGEHKSHLEFSDTQYRELFRYAQEV 474
GA +KFQ T E+ KY +D K+ Y K +F + +Y+EL YA
Sbjct: 54 GADAIKFQ-TYKAERIASKYSPAYWDVTKENTKSQYELFKKFDKFGEDEYKELAGYAANT 112
Query: 475 GILFTASAMDMDLLTF 522
ILF ++ D + + F
Sbjct: 113 DILFMSTPFDNEAVDF 128
>UniRef50_Q58465 Cluster: Uncharacterized protein MJ1065; n=1;
Methanocaldococcus jannaschii|Rep: Uncharacterized
protein MJ1065 - Methanococcus jannaschii
Length = 337
Score = 58.4 bits (135), Expect = 2e-07
Identities = 30/83 (36%), Positives = 45/83 (54%), Gaps = 1/83 (1%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH-KQ 692
D L + VP +I SGD L+ A P+I+STGM D + ++ ++ +
Sbjct: 105 DILNKMNVPAFKIASGDLTFYPLLEKVAKTGKPVILSTGMSDIGEIWEAVKVLENNGCRD 164
Query: 693 FCLLHCISAYPVPFEDCNLTVLQ 761
LLHCIS+YP P+ED NL ++
Sbjct: 165 IILLHCISSYPTPYEDVNLNAIK 187
>UniRef50_Q07IS3 Cluster: N-acetylneuraminate synthase; n=1;
Rhodopseudomonas palustris BisA53|Rep:
N-acetylneuraminate synthase - Rhodopseudomonas
palustris (strain BisA53)
Length = 357
Score = 58.0 bits (134), Expect = 2e-07
Identities = 29/84 (34%), Positives = 44/84 (52%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK 689
S + L + +P +I SGD N LK AS P+I+STG + Y+ I ++
Sbjct: 117 SAELLEEIDMPGFKIASGDLVNTPLLKKVASYGKPIIVSTGGGTLADARLAYETIMPINR 176
Query: 690 QFCLLHCISAYPVPFEDCNLTVLQ 761
C++ C S YP P E+ NL V++
Sbjct: 177 NLCIMQCTSGYPPPHEELNLRVIE 200
Score = 57.6 bits (133), Expect = 3e-07
Identities = 28/69 (40%), Positives = 40/69 (57%)
Frame = +1
Query: 298 GASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVG 477
GA VK QK FT + + YD+ N++ TYG H+ LEF+ QY EL Y +++
Sbjct: 46 GADAVKIQKRDNRALFTAEMYDSHYDSENAYAHTYGTHRECLEFNREQYLELKEYCKQLD 105
Query: 478 ILFTASAMD 504
ILF ++A D
Sbjct: 106 ILFFSTAFD 114
>UniRef50_A4B2T9 Cluster: NeuB:Antifreeze-like protein; n=1;
Alteromonas macleodii 'Deep ecotype'|Rep:
NeuB:Antifreeze-like protein - Alteromonas macleodii
'Deep ecotype'
Length = 347
Score = 57.6 bits (133), Expect = 3e-07
Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQ 692
D L +L P +I S + +L +KY ASK P+++STGM +T + + + + ++ +
Sbjct: 116 DLLESLNTPAYKIASFEIVDLPLVKYIASKNKPILMSTGMASQTEIEEAVTSVRANGDCE 175
Query: 693 FCLLHCISAYPVPFEDCNL 749
L HCIS+YP ED NL
Sbjct: 176 LLLFHCISSYPAVTEDSNL 194
>UniRef50_Q97H26 Cluster: Sialic acid synthase; n=14; cellular
organisms|Rep: Sialic acid synthase - Clostridium
acetobutylicum
Length = 350
Score = 56.8 bits (131), Expect = 6e-07
Identities = 31/87 (35%), Positives = 52/87 (59%), Gaps = 4/87 (4%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK 689
S DFL ++VP ++ S + ++ F++Y ASK P+I+STG+ + + IY+ +++ +
Sbjct: 119 SVDFLEKMEVPAYKVASFELTDIPFIEYIASKGKPVIMSTGIAE---MGEIYEAVAACRR 175
Query: 690 Q----FCLLHCISAYPVPFEDCNLTVL 758
Q LL C S+YP P ED NL +
Sbjct: 176 QGNENVILLKCSSSYPSPLEDINLKTI 202
>UniRef50_A7DQW3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
N-acylneuraminate-9-phosphate synthase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 349
Score = 56.4 bits (130), Expect = 7e-07
Identities = 27/83 (32%), Positives = 40/83 (48%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK 689
S +FL +P +I S D N + PLI+STGM + ++ + +
Sbjct: 119 SVEFLEKFDLPAYKIASADMTNFPLISSLIQTGKPLIVSTGMSNMNEIEKTVSFMKEKNA 178
Query: 690 QFCLLHCISAYPVPFEDCNLTVL 758
+F LLHC S YP P E NL ++
Sbjct: 179 KFALLHCNSTYPAPVETLNLELI 201
Score = 38.7 bits (86), Expect = 0.16
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Frame = +1
Query: 298 GASCVKFQKTCLGEKFTKKYLERPYDNPNSWG-KTYGEHKSHLEFSDTQYRELFRYAQEV 474
GA+ VKFQK L + + + L+ P N S G + + + +EF D Y+EL Y +E
Sbjct: 49 GANAVKFQKRSLNDIYREDVLKDP--NIESQGLEILLDVLNEVEFDDDAYKELTEYCKEK 106
Query: 475 GILFTASAMDMDLLTF 522
I F + D+ + F
Sbjct: 107 HITFLCTPWDIPSVEF 122
>UniRef50_A3V3D1 Cluster: Polysialic acid capsule biosynthesis
protein SiaC; n=3; Bacteria|Rep: Polysialic acid capsule
biosynthesis protein SiaC - Loktanella vestfoldensis
SKA53
Length = 343
Score = 56.0 bits (129), Expect = 1e-06
Identities = 28/78 (35%), Positives = 45/78 (57%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQF 695
DFL +L VP +IGSG+++NL +++ A P+I+STGM +++ I+ +
Sbjct: 112 DFLQDLDVPAFKIGSGEADNLPLIRHIARMGKPVIMSTGMQSIESIRASVAILDGAGVDY 171
Query: 696 CLLHCISAYPVPFEDCNL 749
LL C + YP P E +L
Sbjct: 172 ALLECTNLYPSPPEIVSL 189
>UniRef50_Q3XXA4 Cluster: N-acetylneuraminate synthase; n=1;
Enterococcus faecium DO|Rep: N-acetylneuraminate
synthase - Enterococcus faecium DO
Length = 335
Score = 55.6 bits (128), Expect = 1e-06
Identities = 32/83 (38%), Positives = 41/83 (49%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK 689
S DFL + V +IGSGD NL FL+ +P+++STGM D V D
Sbjct: 106 SADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFID--S 163
Query: 690 QFCLLHCISAYPVPFEDCNLTVL 758
+LHC S YP ED NL +
Sbjct: 164 PVTILHCTSNYPASSEDINLLAI 186
>UniRef50_Q12JI6 Cluster: N-acetylneuraminic acid synthase-like
protein; n=1; Shewanella denitrificans OS217|Rep:
N-acetylneuraminic acid synthase-like protein -
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 /
DSM 15013)
Length = 359
Score = 55.6 bits (128), Expect = 1e-06
Identities = 26/81 (32%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISS-DH 686
+ + L + + P +I S + N++ + AA P+++STG+ ++ + +++
Sbjct: 119 AIELLESCECPAYKISSFEINDIGLIMAAAKTGKPIVMSTGLATLAEIEEAVEAVANAGG 178
Query: 687 KQFCLLHCISAYPVPFEDCNL 749
Q LLHCIS YP P EDCNL
Sbjct: 179 TQLALLHCISGYPTPIEDCNL 199
>UniRef50_Q8TJL5 Cluster: N-acetylneuraminic acid phosphate
synthase; n=11; cellular organisms|Rep:
N-acetylneuraminic acid phosphate synthase -
Methanosarcina acetivorans
Length = 286
Score = 55.6 bits (128), Expect = 1e-06
Identities = 26/67 (38%), Positives = 42/67 (62%), Gaps = 1/67 (1%)
Frame = +1
Query: 310 VKFQKTCLGEKFTKKYLERPYDNP-NSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILF 486
VKFQK E T + P+ P NS+GKTYGEH+ LEF+ Q+++L ++ + G+++
Sbjct: 37 VKFQKRTPVELLTPEEYNAPHPVPHNSYGKTYGEHREFLEFNLDQHKQLKKWCDDWGVVY 96
Query: 487 TASAMDM 507
+ S D+
Sbjct: 97 STSVWDL 103
>UniRef50_A4U173 Cluster: NeuB; n=1; Magnetospirillum
gryphiswaldense|Rep: NeuB - Magnetospirillum
gryphiswaldense
Length = 337
Score = 55.2 bits (127), Expect = 2e-06
Identities = 25/70 (35%), Positives = 40/70 (57%), Gaps = 1/70 (1%)
Frame = +3
Query: 555 GSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIIS-SDHKQFCLLHCISAYPVP 731
GS D N FL+ A K P+++STGM ++ D+I+ + + + LLHC+ +YP
Sbjct: 121 GSDDLTNTRFLRQIAEKGRPMVVSTGMCTLAEIERAVDVITRTGNTELILLHCVVSYPAK 180
Query: 732 FEDCNLTVLQ 761
ED NL ++
Sbjct: 181 AEDANLRAIE 190
>UniRef50_Q46675 Cluster: NeuB protein; n=8; Bacteria|Rep: NeuB
protein - Escherichia coli
Length = 346
Score = 54.4 bits (125), Expect = 3e-06
Identities = 34/89 (38%), Positives = 46/89 (51%), Gaps = 6/89 (6%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIP---LIISTGMVDKTAVKTIYDIISS 680
S DFL +LK +I SG+ NL +L+ A IP +IISTGM +K I +
Sbjct: 104 SIDFLASLKQKIWKIPSGELLNLPYLEKIAKLPIPDKKIIISTGMATIDEIKQSVSIFIN 163
Query: 681 DHK---QFCLLHCISAYPVPFEDCNLTVL 758
+ +LHC + YP PFED NL +
Sbjct: 164 NKVPVGNITILHCNTEYPTPFEDVNLNAI 192
>UniRef50_Q2N2P7 Cluster: NeuB; n=7; Proteobacteria|Rep: NeuB -
Aeromonas hydrophila
Length = 345
Score = 54.4 bits (125), Expect = 3e-06
Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 1/82 (1%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDI-ISSDHKQ 692
D L +L P +I S + +L ++YAA PLI+STGM ++ + ++ + Q
Sbjct: 116 DLLESLDCPAYKIASFELVDLPLIRYAAQTGKPLIMSTGMANEAEIAAAVEMALKHGSGQ 175
Query: 693 FCLLHCISAYPVPFEDCNLTVL 758
LLHC+S YP P + NL +
Sbjct: 176 LALLHCVSGYPAPAAEYNLRTI 197
>UniRef50_Q7VHQ5 Cluster: Sialic acid synthase; n=6;
Helicobacter|Rep: Sialic acid synthase - Helicobacter
hepaticus
Length = 349
Score = 54.0 bits (124), Expect = 4e-06
Identities = 29/81 (35%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Frame = +3
Query: 519 FLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISS-DHKQF 695
FL +L+ P ++ S + + ++ A K P+IISTG+ +KT +I K
Sbjct: 117 FLESLQCPIYKVASFEVMHYELIEAIAKTKKPIIISTGVATHKELKTALEICHKYGCKDI 176
Query: 696 CLLHCISAYPVPFEDCNLTVL 758
LLHCIS YP P E NL +
Sbjct: 177 TLLHCISEYPAPLESANLLAM 197
>UniRef50_Q1PVV9 Cluster: Similarity to N-acetyl neuramic acid
synthetase NeuB; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similarity to N-acetyl neuramic
acid synthetase NeuB - Candidatus Kuenenia
stuttgartiensis
Length = 277
Score = 54.0 bits (124), Expect = 4e-06
Identities = 25/83 (30%), Positives = 44/83 (53%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK 689
S DFL ++ ++ S D N L A K +I+S GM + + ++ + I+ +
Sbjct: 101 SVDFLESVNCALYKVASFDVVNYKLLSKIADTKKTIIMSVGMANLSEIEGAFKILKNKTD 160
Query: 690 QFCLLHCISAYPVPFEDCNLTVL 758
+ ++HC+SAYP ED NL+ +
Sbjct: 161 KLAIMHCVSAYPTKEEDANLSAI 183
>UniRef50_Q04TM5 Cluster: N-acetylneuraminic acid (Sialic acid)
synthetase; n=2; Leptospira borgpetersenii serovar
Hardjo-bovis|Rep: N-acetylneuraminic acid (Sialic acid)
synthetase - Leptospira borgpetersenii serovar
Hardjo-bovis (strain JB197)
Length = 282
Score = 53.2 bits (122), Expect = 7e-06
Identities = 26/84 (30%), Positives = 44/84 (52%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK 689
+ + L + V ++I S D N+ L+ AA + +I+S G + ++T I
Sbjct: 104 NLNMLKEIGVEILKIASCDICNITLLEAAADSGLIVILSRGTASASEIETAVSIFKKKKS 163
Query: 690 QFCLLHCISAYPVPFEDCNLTVLQ 761
F LLHC+S+YP+ D NL+ +Q
Sbjct: 164 PFILLHCVSSYPMNEIDANLSAIQ 187
Score = 40.3 bits (90), Expect = 0.051
Identities = 17/22 (77%), Positives = 19/22 (86%)
Frame = +2
Query: 188 DIRIGGNNPCFIIAEAGQNHQG 253
+I+IGGNNP FIIAEAG NH G
Sbjct: 9 NIKIGGNNPVFIIAEAGLNHGG 30
>UniRef50_P39625 Cluster: Spore coat polysaccharide biosynthesis
protein spsE; n=2; Bacillus|Rep: Spore coat
polysaccharide biosynthesis protein spsE - Bacillus
subtilis
Length = 373
Score = 52.4 bits (120), Expect = 1e-05
Identities = 30/94 (31%), Positives = 49/94 (52%), Gaps = 1/94 (1%)
Frame = +3
Query: 480 FIHRLCHGHGSFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKT 659
F+ +C GS D L + +I S + N+L LKY A P+I ST + + V
Sbjct: 105 FLSTVCD-EGSADLLQSTSPSAFKIASYEINHLPLLKYVARLNRPMIFSTAGAEISDVHE 163
Query: 660 IYDIISSD-HKQFCLLHCISAYPVPFEDCNLTVL 758
+ I ++ + Q ++HC++ YP P E NL+V+
Sbjct: 164 AWRTIRAEGNNQIAIMHCVAKYPAPPEYSNLSVI 197
>UniRef50_Q0A628 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Alkalilimnicola ehrlichei MLHE-1|Rep:
N-acylneuraminate-9-phosphate synthase - Alkalilimnicola
ehrlichei (strain MLHE-1)
Length = 348
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/83 (31%), Positives = 42/83 (50%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK 689
S D L L + ++ S D + L+ A K P+++STG V++ +++ S+
Sbjct: 114 SVDLLDGLGMAAFKVASADITHRPLLQDIAGKGKPVLLSTGAASMAEVRSALEVLESEGV 173
Query: 690 QFCLLHCISAYPVPFEDCNLTVL 758
LLHC AYP P + NL+ L
Sbjct: 174 PVALLHCSLAYPTPVDQANLSRL 196
>UniRef50_Q0M1E8 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Caulobacter sp. K31
Length = 310
Score = 51.2 bits (117), Expect = 3e-05
Identities = 27/75 (36%), Positives = 39/75 (52%)
Frame = +1
Query: 298 GASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVG 477
G VKFQK + +T + L +P +P WG T K LEF +Y + Y +E+G
Sbjct: 61 GCDAVKFQKRTIDIVYTPEVLAQPRQSP--WGDTQRAQKEGLEFGKAEYDVIDAYCRELG 118
Query: 478 ILFTASAMDMDLLTF 522
+ + ASA D+ TF
Sbjct: 119 LAWFASAWDVPSQTF 133
Score = 39.5 bits (88), Expect = 0.089
Identities = 22/80 (27%), Positives = 38/80 (47%)
Frame = +3
Query: 519 FLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFC 698
FL +P+ +I S + ++ A++ + STGM + T +I+ + F
Sbjct: 133 FLAAYDLPYNKIASAMLTHRPLIEAVAAEGKLVFASTGMCTFEQIDTAVEILRAAACPFV 192
Query: 699 LLHCISAYPVPFEDCNLTVL 758
L+H +S YP P D NL +
Sbjct: 193 LMHTVSTYPTPPADLNLLTI 212
>UniRef50_Q0IDR1 Cluster: N-acetylneuraminic acid condensing enzyme;
n=1; Synechococcus sp. CC9311|Rep: N-acetylneuraminic
acid condensing enzyme - Synechococcus sp. (strain
CC9311)
Length = 347
Score = 51.2 bits (117), Expect = 3e-05
Identities = 30/85 (35%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIIS--SD 683
S F+ NLK I+ SG+ N + L AA ++P+I+STGM + + + D I+
Sbjct: 117 SLRFIANLKPVAIKWASGELTNKMLLDQAAKTRLPIILSTGM---SRINDVDDAITWIGR 173
Query: 684 HKQFCLLHCISAYPVPFEDCNLTVL 758
+ +L C+S YP D NL VL
Sbjct: 174 NTPLVVLQCVSNYPAAMSDQNLRVL 198
>UniRef50_Q3AZQ1 Cluster: N-acylneuraminate-9-phosphate synthase;
n=17; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Synechococcus sp. (strain CC9902)
Length = 762
Score = 50.4 bits (115), Expect = 5e-05
Identities = 27/72 (37%), Positives = 41/72 (56%), Gaps = 1/72 (1%)
Frame = +3
Query: 549 QIGSGD-SNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYP 725
++ S D +N+ L + AA+ K PLI STGM + +++ + + LLHC S YP
Sbjct: 245 KVASADFTNHALITQLAATGK-PLICSTGMASELEIRSGIRHLQKAGANYVLLHCNSTYP 303
Query: 726 VPFEDCNLTVLQ 761
PF+D NL L+
Sbjct: 304 TPFKDVNLRYLE 315
Score = 33.9 bits (74), Expect = 4.4
Identities = 12/19 (63%), Positives = 14/19 (73%)
Frame = +2
Query: 197 IGGNNPCFIIAEAGQNHQG 253
IG +PCF+IAE G NH G
Sbjct: 128 IGAEHPCFVIAEIGNNHNG 146
>UniRef50_A5MZ25 Cluster: Predicted polysaccharide biosynthesis
protein; n=1; Clostridium kluyveri DSM 555|Rep:
Predicted polysaccharide biosynthesis protein -
Clostridium kluyveri DSM 555
Length = 335
Score = 50.4 bits (115), Expect = 5e-05
Identities = 27/83 (32%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH-KQ 692
D L L + +I SGD + L Y ++ P+I+++GM VK ++ I + +
Sbjct: 105 DLLEKLNIEGYKIASGDMDYYPLLDYISNTGKPIILASGMAYMDEVKEAFNRIKNGKTED 164
Query: 693 FCLLHCISAYPVPFEDCNLTVLQ 761
+LHC+S YP ED NL +Q
Sbjct: 165 IAILHCVSNYPPKDEDINLKAIQ 187
Score = 39.5 bits (88), Expect = 0.089
Identities = 22/64 (34%), Positives = 31/64 (48%)
Frame = +2
Query: 164 MVEVKITDDIRIGGNNPCFIIAEAGQNHQGASRSQXXXXXXXXXXXXAA*SFKRHVSERN 343
M ++KI + I IG +PCFIIAEAG NH G + A F+ +++
Sbjct: 1 MNDIKIGNKI-IGNTHPCFIIAEAGSNHNGDIKQAKELVDIAVEAGANAVKFQTFTADKL 59
Query: 344 LQKN 355
KN
Sbjct: 60 FSKN 63
>UniRef50_Q1IMQ8 Cluster: N-acetylneuraminate synthase; n=16;
Bacteria|Rep: N-acetylneuraminate synthase -
Acidobacteria bacterium (strain Ellin345)
Length = 300
Score = 49.6 bits (113), Expect = 8e-05
Identities = 27/69 (39%), Positives = 40/69 (57%)
Frame = +1
Query: 298 GASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVG 477
G VKFQK + +T L +P +NP +G T G+ K LEF +++E+ RY +EV
Sbjct: 54 GCDAVKFQKRTIDVVYTAAELAKPRENP--FGATNGDLKRGLEFGLEEFKEIDRYCREVR 111
Query: 478 ILFTASAMD 504
+ + ASA D
Sbjct: 112 MPWFASAWD 120
Score = 42.7 bits (96), Expect = 0.010
Identities = 23/83 (27%), Positives = 39/83 (46%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK 689
S DF+ VP +I S + L++ + P+++STGM + D++ D+
Sbjct: 123 SVDFIAQFDVPCFKIASASLTDDNLLRHTRATGKPVMLSTGMSTVEQIDHAVDVLGKDN- 181
Query: 690 QFCLLHCISAYPVPFEDCNLTVL 758
LL S YP +E+ NL +
Sbjct: 182 -LILLQACSTYPAYYEELNLKAI 203
>UniRef50_A3Y8V9 Cluster: NeuB family protein; n=1; Marinomonas sp.
MED121|Rep: NeuB family protein - Marinomonas sp. MED121
Length = 347
Score = 49.6 bits (113), Expect = 8e-05
Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIIS-SDHKQ 692
+FL +L VP +I S + +L ++ A P+I+STGM K+ ++ ++ +
Sbjct: 114 NFLESLDVPIYKIASFELTDLPLIEAVARTGKPMIMSTGMATKSEIEEAVSLVRLIGDNE 173
Query: 693 FCLLHCISAYPVPFEDCNLTVL 758
LL C S YP ED NL L
Sbjct: 174 ITLLKCTSTYPAKIEDSNLITL 195
>UniRef50_Q893U6 Cluster: N-acetylneuraminate synthase; n=1;
Clostridium tetani|Rep: N-acetylneuraminate synthase -
Clostridium tetani
Length = 351
Score = 49.2 bits (112), Expect = 1e-04
Identities = 26/83 (31%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDK-TAVKTIYDIISSDHKQ 692
+FL L+VP ++ + D + L LK K P+++S G A I +I S ++
Sbjct: 120 EFLNELEVPCFKVAASDVDYLDILKEIGKTKKPVMLSLGKCTLGEADLAIETLIESGCEK 179
Query: 693 FCLLHCISAYPVPFEDCNLTVLQ 761
++HC+S YP P + NL V++
Sbjct: 180 IVIMHCVSQYPSPINEMNLKVIE 202
>UniRef50_Q4VKA5 Cluster: NeuNAc condensing enzyme; n=54; cellular
organisms|Rep: NeuNAc condensing enzyme - Escherichia
coli
Length = 350
Score = 48.4 bits (110), Expect = 2e-04
Identities = 33/90 (36%), Positives = 47/90 (52%), Gaps = 7/90 (7%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIP---LIISTGM--VDKT--AVKTIYD 668
S DFL + +I SG+ NL +L+ A I +++STGM VD+ A+K D
Sbjct: 108 SIDFLASRNQKVWKIPSGELLNLPYLEKIAKLPIEDKKIVLSTGMATVDEINLALKVFID 167
Query: 669 IISSDHKQFCLLHCISAYPVPFEDCNLTVL 758
H+ +LHC + YP PFED NL +
Sbjct: 168 N-GITHRNITILHCNTEYPTPFEDVNLNTI 196
>UniRef50_A2C5V5 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. MIT 9303|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain MIT 9303)
Length = 335
Score = 48.0 bits (109), Expect = 3e-04
Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Frame = +3
Query: 501 GHGSFDFLVNLKVPFIQIGSGDSNNLLFLKYAASK----KIPLIISTGMVDKTAVKTIYD 668
G D L+ LKV I++ SG+ + LK A K + + +STGM + ++ D
Sbjct: 99 GQSQLDLLIKLKVQAIKVASGEITHWPLLKEMAKKAYENNLDVYLSTGMSEIKEIQDALD 158
Query: 669 I-ISSDHK--QFCLLHCISAYPVPFEDCNLTVLQ 761
I I D + +LHC S YP P+ N+ L+
Sbjct: 159 IFIKEDISLGKIFILHCTSHYPAPYNAVNMKALR 192
>UniRef50_A1WSD6 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Verminephrobacter eiseniae EF01-2|Rep:
N-acylneuraminate-9-phosphate synthase -
Verminephrobacter eiseniae (strain EF01-2)
Length = 352
Score = 48.0 bits (109), Expect = 3e-04
Identities = 28/88 (31%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
Frame = +3
Query: 504 HGSFDFLVN-LKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISS 680
HGS DFL + L ++I S + +N L++ A + L++STG V D +++
Sbjct: 113 HGSVDFLADRLGCKTVKIPSPEVSNKPLLQHMARRFDGLLLSTGASYLGEVANAIDWLAA 172
Query: 681 DH--KQFCLLHCISAYPVPFEDCNLTVL 758
+ ++ L+HC+S YP P E NL +
Sbjct: 173 EAGPRELALMHCLSEYPAPVEQANLRAM 200
>UniRef50_Q726U8 Cluster: NeuB family protein; n=2; Desulfovibrio
vulgaris subsp. vulgaris|Rep: NeuB family protein -
Desulfovibrio vulgaris (strain Hildenborough / ATCC
29579 / NCIMB8303)
Length = 358
Score = 47.6 bits (108), Expect = 3e-04
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDH 686
+ D ++ +++ S D +N L+ A +P+I+S GM D + K + + S
Sbjct: 108 TLDLCTRFRIAAVKVASMDLDNTAHLRAVARTGLPVILSCGMGDHADIGKALATLRESGA 167
Query: 687 KQFCLLHCISAYPVPFEDCNL 749
LLHCIS YP ED L
Sbjct: 168 TDVTLLHCISDYPARLEDMQL 188
>UniRef50_A4AP54 Cluster: N-acetylneuraminate synthase; n=3;
cellular organisms|Rep: N-acetylneuraminate synthase -
Flavobacteriales bacterium HTCC2170
Length = 351
Score = 47.6 bits (108), Expect = 3e-04
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQ 692
DFL L V +I SG L FL++ A P+I+S+GM V + + I + + Q
Sbjct: 119 DFLNKLGVSAFKIASGQIVELAFLEHVAKFGKPIILSSGMATLAEVYEAVMTIREAGNNQ 178
Query: 693 FCLLHCISAYPVPFEDCNLTVL 758
+L C + YP ED N+ +
Sbjct: 179 MAILQCTTNYPSQNEDANIRAM 200
Score = 36.3 bits (80), Expect = 0.83
Identities = 17/30 (56%), Positives = 20/30 (66%)
Frame = +2
Query: 164 MVEVKITDDIRIGGNNPCFIIAEAGQNHQG 253
M +KI +D I +PCFIIAEAG NH G
Sbjct: 1 MKSIKI-EDFLISKESPCFIIAEAGVNHNG 29
>UniRef50_Q93NQ2 Cluster: NnaB; n=7; Bacteria|Rep: NnaB -
Escherichia coli
Length = 346
Score = 45.2 bits (102), Expect = 0.002
Identities = 26/86 (30%), Positives = 46/86 (53%), Gaps = 6/86 (6%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIP---LIISTGMVDKTAVKTIYDIISS 680
S DFL + +I SG+ NL +L+ + I +++STGM +K ++++
Sbjct: 104 SIDFLASRNQKMWKIPSGELLNLPYLEKISRLPIEGKEIVLSTGMATIEEIKASVNVLTK 163
Query: 681 DH---KQFCLLHCISAYPVPFEDCNL 749
+ ++ +LHC + YP P+ED NL
Sbjct: 164 NGMAPEKITILHCNTEYPTPYEDVNL 189
>UniRef50_Q89HJ8 Cluster: Blr5992 protein; n=2; Proteobacteria|Rep:
Blr5992 protein - Bradyrhizobium japonicum
Length = 356
Score = 44.8 bits (101), Expect = 0.002
Identities = 33/109 (30%), Positives = 48/109 (44%), Gaps = 26/109 (23%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH- 686
S FL++LK+P I+IGSGD N L AA LI+STGM + ++ +++ +
Sbjct: 105 SLGFLLSLKLPRIKIGSGDLTNAPLLHAAARAGATLILSTGMATLSEIEEALGVLAHGYA 164
Query: 687 -------------------------KQFCLLHCISAYPVPFEDCNLTVL 758
+ LLHC + YP P ED NL +
Sbjct: 165 QRSDPAGVASFRAAWRDPAARATLARHVSLLHCTTEYPCPIEDVNLAAM 213
>UniRef50_A3PE56 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. MIT 9301|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain MIT 9301)
Length = 341
Score = 44.8 bits (101), Expect = 0.002
Identities = 26/92 (28%), Positives = 48/92 (52%), Gaps = 6/92 (6%)
Frame = +3
Query: 501 GHGSFDFLVNLKVPFIQIGSGDSNNLLFL----KYAASKKIPLIISTGMVDKTAVKTIYD 668
G FL++L + I+I SG+ N + K+ + I +++STGM ++
Sbjct: 99 GVDELHFLLDLGMLSIKIPSGEITNYALISEIGKFISEGNINVLLSTGMSSLGDIEEALS 158
Query: 669 IISSDH--KQFCLLHCISAYPVPFEDCNLTVL 758
++ ++ ++HC+S+YP P +D NL VL
Sbjct: 159 LLRFKETLERITIMHCVSSYPAPNKDLNLKVL 190
>UniRef50_Q11RF6 Cluster: N-acetylneuraminic acid synthetase; n=2;
Flexibacteraceae|Rep: N-acetylneuraminic acid synthetase
- Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB
9469)
Length = 348
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH-KQ 692
DFL +L VP +I S ++ + + LK A P+I+STG+ ++ ++ + K+
Sbjct: 119 DFLESLDVPCYKIASFENTDHILLKKVAQTNKPVIMSTGVSTIADIQESVKVLRDNGCKE 178
Query: 693 FCLLHCISAYPVPFEDCNL 749
LL C S YP E N+
Sbjct: 179 LVLLKCTSTYPATPESTNI 197
>UniRef50_Q04TP3 Cluster: N-acetylneuraminic acid (Sialic acid)
synthetase; n=6; Bacteria|Rep: N-acetylneuraminic acid
(Sialic acid) synthetase - Leptospira borgpetersenii
serovar Hardjo-bovis (strain JB197)
Length = 364
Score = 44.4 bits (100), Expect = 0.003
Identities = 23/77 (29%), Positives = 42/77 (54%), Gaps = 1/77 (1%)
Frame = +3
Query: 534 KVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVK-TIYDIISSDHKQFCLLHC 710
++PFI++ S D ++ L+ A P+I+STG + + ++ ++ + LLHC
Sbjct: 134 QMPFIKVASADITSVPLLRSVAKYSKPVILSTGSSTIPEIDFAMRELHANGANEIILLHC 193
Query: 711 ISAYPVPFEDCNLTVLQ 761
I YP E+ NL ++Q
Sbjct: 194 ILNYPTKPENANLGMIQ 210
>UniRef50_A6W187 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Proteobacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Marinomonas sp. MWYL1
Length = 343
Score = 44.0 bits (99), Expect = 0.004
Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Frame = +3
Query: 519 FLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQF 695
FL ++ VP +I S + ++ ++ A P+I+STGM + + + + I +
Sbjct: 115 FLESIDVPLYKIASFEMTDIPLIQAVARTGKPIIMSTGMASEEEIAEAVATIRAIGDNPL 174
Query: 696 CLLHCISAYPVPFEDCNLTVL 758
LL C S YP ED NL +
Sbjct: 175 TLLKCTSTYPSKIEDSNLVTM 195
>UniRef50_A0LYV7 Cluster: N-acetylneuraminate synthase; n=1;
Gramella forsetii KT0803|Rep: N-acetylneuraminate
synthase - Gramella forsetii (strain KT0803)
Length = 332
Score = 44.0 bits (99), Expect = 0.004
Identities = 26/86 (30%), Positives = 40/86 (46%)
Frame = +3
Query: 504 HGSFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD 683
+ + D L + V +IGSG+ NN L L+ A +IIS+GM + +
Sbjct: 96 NAAVDLLEEVGVKRYKIGSGEVNNFLLLEKIAKTGKQVIISSGMSSFDELDATVSFLRER 155
Query: 684 HKQFCLLHCISAYPVPFEDCNLTVLQ 761
F LL C ++YP + L V+Q
Sbjct: 156 KISFSLLQCTTSYPTTPANYGLNVIQ 181
>UniRef50_A5W0I0 Cluster: N-acetylneuraminic acid synthase,
N-terminal domain; n=1; Pseudomonas putida F1|Rep:
N-acetylneuraminic acid synthase, N-terminal domain -
Pseudomonas putida F1
Length = 369
Score = 43.6 bits (98), Expect = 0.005
Identities = 24/80 (30%), Positives = 36/80 (45%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK 689
S D V +P I+I S D N+ ++ AS + P IISTG + + I
Sbjct: 111 SVDLCVEFDMPIIKIASSDMNDWPLIEKIASTRRPTIISTGGASEKDLDDIVRYFEKRDI 170
Query: 690 QFCLLHCISAYPVPFEDCNL 749
+ HC+S YP ++ L
Sbjct: 171 PLAINHCVSLYPSEDDELQL 190
>UniRef50_Q8EC83 Cluster: Polysaccharide biosynthesis
related-protein; n=6; Proteobacteria|Rep: Polysaccharide
biosynthesis related-protein - Shewanella oneidensis
Length = 290
Score = 43.2 bits (97), Expect = 0.007
Identities = 24/53 (45%), Positives = 32/53 (60%), Gaps = 4/53 (7%)
Frame = +3
Query: 612 PLIISTGMVD----KTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNLTVL 758
P++IS GM A+KT+ + +SD LLHC+SAYP P +CNL VL
Sbjct: 129 PVVISAGMATIEEIDHALKTLKENGASD---ITLLHCVSAYPTPEHECNLAVL 178
>UniRef50_Q8DDZ7 Cluster: Sialic acid synthase; n=5; Bacteria|Rep:
Sialic acid synthase - Vibrio vulnificus
Length = 333
Score = 43.2 bits (97), Expect = 0.007
Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 5/89 (5%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGM----VDKTAVKTIYDI-I 674
S FL L+ F +IGSG+ N FL++ AS P+I+STGM + AV T+ D +
Sbjct: 105 SATFLDGLQAVF-KIGSGELTNTPFLRHIASFAKPVILSTGMGYLSEVEHAVVTLRDAGL 163
Query: 675 SSDHKQFCLLHCISAYPVPFEDCNLTVLQ 761
S D +LH + YP ED NL ++
Sbjct: 164 SLD--MITVLHATTDYPTAPEDVNLLAMK 190
>UniRef50_O83573 Cluster: Spore coat polysaccharide biosynthesis
protein; n=1; Treponema pallidum|Rep: Spore coat
polysaccharide biosynthesis protein - Treponema pallidum
Length = 378
Score = 43.2 bits (97), Expect = 0.007
Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 3/81 (3%)
Frame = +3
Query: 531 LKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQ---FCL 701
LK F+++ S + N + A+ ++PLI+S+G+ ++ KQ L
Sbjct: 118 LKPDFLKVASPELNYPTLISTLAAAELPLILSSGVCLLKEIEGALAQCRQYTKQGSSHAL 177
Query: 702 LHCISAYPVPFEDCNLTVLQA 764
LHCI+AYP P + NL +L A
Sbjct: 178 LHCITAYPAPETEYNLALLPA 198
>UniRef50_Q0P8U0 Cluster: Pse synthetase; n=14; Campylobacter|Rep:
Pse synthetase - Campylobacter jejuni
Length = 343
Score = 42.3 bits (95), Expect = 0.013
Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-HKQ 692
+FL +I S ++N+ F++ A +K P I+STG+ + + I +I + +
Sbjct: 114 EFLKRFDPIAYKIASFEANDENFVRLIAKEKKPTIVSTGIATEEELFKICEIFKEEKNPD 173
Query: 693 FCLLHCISAYPVPFEDCNL 749
L C S YP ED NL
Sbjct: 174 LVFLKCTSTYPTAIEDMNL 192
>UniRef50_UPI0000384B44 Cluster: COG2089: Sialic acid synthase; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG2089:
Sialic acid synthase - Magnetospirillum magnetotacticum
MS-1
Length = 346
Score = 41.9 bits (94), Expect = 0.017
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +3
Query: 501 GHGSFDFLVN-LKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDII 674
G S FLV L +P ++IGS + + +L+ P I+STG+ V K + +
Sbjct: 110 GFDSLAFLVGELDMPIVKIGSTEVTHPQYLEAIGRTGRPAILSTGLSTLGEVEKAVAALR 169
Query: 675 SSDHKQFCLLHCISAYPVPFEDCNLTVL 758
LLHC S YP P NL +
Sbjct: 170 RGGVGPLALLHCTSEYPAPDSQMNLRAM 197
>UniRef50_Q2BJD7 Cluster: N-acetylneuraminic acid synthetase; n=1;
Neptuniibacter caesariensis|Rep: N-acetylneuraminic acid
synthetase - Neptuniibacter caesariensis
Length = 270
Score = 41.1 bits (92), Expect = 0.029
Identities = 21/81 (25%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISS---DH 686
+F+ I+I S + N+ ++YA S + +S G + +K + +++ S +
Sbjct: 92 EFVSQFSTEAIKIPSHEVANIELIRYALSTYKRVFLSLGACTEEELKDVSELVGSIRSNG 151
Query: 687 KQFCLLHCISAYPVPFEDCNL 749
+ +HC+S+YP P E NL
Sbjct: 152 EDVVAMHCVSSYPCPVEKVNL 172
>UniRef50_Q30V22 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Desulfovibrio desulfuricans G20|Rep:
N-acylneuraminate-9-phosphate synthase - Desulfovibrio
desulfuricans (strain G20)
Length = 344
Score = 40.7 bits (91), Expect = 0.039
Identities = 29/76 (38%), Positives = 38/76 (50%), Gaps = 6/76 (7%)
Frame = +3
Query: 555 GSGDSNNLLFLKYAASKKIPLIISTGMVD----KTAVKTIYDIISSDHKQ--FCLLHCIS 716
GSGD L+ S PL++STG+ + AV+ I + SS Q LL C S
Sbjct: 113 GSGDLTAYPMLRALVSTGKPLVLSTGLSTMPEVEAAVRYIGSLDSSYITQGKLALLQCSS 172
Query: 717 AYPVPFEDCNLTVLQA 764
AYP P D NL V+ +
Sbjct: 173 AYPCPDGDANLNVMHS 188
>UniRef50_A1RHT0 Cluster: N-acylneuraminate-9-phosphate synthase;
n=29; cellular organisms|Rep:
N-acylneuraminate-9-phosphate synthase - Shewanella sp.
(strain W3-18-1)
Length = 349
Score = 40.3 bits (90), Expect = 0.051
Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH-KQ 692
++L L VP +I S ++N+ L A P+I+STGM + + ++ +
Sbjct: 121 EYLEKLNVPCYKIASFENNDHALLAAVAKTGKPVIMSTGMAEIHELAEAVTVLKQHGCRD 180
Query: 693 FCLLHCISAYPVPFEDCNLTVL 758
LL C S YP D NL+ +
Sbjct: 181 LILLKCTSHYPAEPVDANLSTI 202
>UniRef50_A0LAB4 Cluster: N-acetylneuraminic acid synthase,
N-terminal domain; n=2; Proteobacteria|Rep:
N-acetylneuraminic acid synthase, N-terminal domain -
Magnetococcus sp. (strain MC-1)
Length = 500
Score = 39.9 bits (89), Expect = 0.068
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Frame = +3
Query: 537 VPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVK-TIYDIISSDHKQFCLLHCI 713
VP +I S + ++L L AA+ PL++STG + + S + CLL C
Sbjct: 272 VPLHKIASYEISHLRLLDLAANSGKPLLLSTGASRAEDIAWAVERYHSQGGRDLCLLQCT 331
Query: 714 SAYPVPFEDCNLTVL 758
+ YP P N VL
Sbjct: 332 AKYPAPLATVNSAVL 346
>UniRef50_Q18EL3 Cluster: Sialic acid synthase; n=1; Haloquadratum
walsbyi DSM 16790|Rep: Sialic acid synthase -
Haloquadratum walsbyi (strain DSM 16790)
Length = 391
Score = 39.9 bits (89), Expect = 0.068
Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Frame = +3
Query: 510 SFDFLVNLKVPFIQIGSGDSNN---LLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISS 680
S F++ +P++++ S +S N L L+ K L+IS G VK
Sbjct: 191 SLHFVLEYNMPYVKVASTNSRNDEMLTELRDKVPKNTGLVISIGGSTMNEVKDTLSHFP- 249
Query: 681 DHKQFCLLHCISAYPVPFEDCNL 749
DH L HC+S YPVP E+ L
Sbjct: 250 DHN-IILQHCVSEYPVPPENLGL 271
>UniRef50_Q5QWT8 Cluster: Sialic acid synthase; n=14; Bacteria|Rep:
Sialic acid synthase - Idiomarina loihiensis
Length = 357
Score = 30.3 bits (65), Expect(2) = 0.096
Identities = 20/58 (34%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +3
Query: 510 SFDFLVN-LKVPFIQIGSGDSNNL-LFLKYAASKKIPLIISTGMVDKTAVKTIYDIIS 677
S +FLVN L + +++ SG+ N L LK+A + LI+STGM ++++ +I+
Sbjct: 102 SLNFLVNDLGLKRLKLPSGEITNAPLVLKHAQTG-CDLIVSTGMATMAEIESVLGVIA 158
Score = 28.3 bits (60), Expect(2) = 0.096
Identities = 9/20 (45%), Positives = 13/20 (65%)
Frame = +3
Query: 699 LLHCISAYPVPFEDCNLTVL 758
+LHC + YP P E+ NL +
Sbjct: 193 VLHCTTEYPAPMEEINLNAM 212
>UniRef50_Q1GST3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Alphaproteobacteria|Rep:
N-acylneuraminate-9-phosphate synthase - Sphingopyxis
alaskensis (Sphingomonas alaskensis)
Length = 350
Score = 39.1 bits (87), Expect = 0.12
Identities = 27/90 (30%), Positives = 38/90 (42%), Gaps = 9/90 (10%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK-- 689
D L+ L + I+I SG+ N + A P+I+STGM + V D I +
Sbjct: 112 DMLLGLGMRRIKIASGEIVNKPLIDKVAGSGRPIILSTGMAEMAEVVRAVDWIRTAQSAA 171
Query: 690 -------QFCLLHCISAYPVPFEDCNLTVL 758
+LHC S YP P NL +
Sbjct: 172 GIAMSPGDLVVLHCTSEYPAPAASVNLRAM 201
>UniRef50_Q89HL9 Cluster: Blr5971 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr5971 protein - Bradyrhizobium
japonicum
Length = 641
Score = 38.7 bits (86), Expect = 0.16
Identities = 20/67 (29%), Positives = 30/67 (44%)
Frame = +3
Query: 549 QIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPV 728
++ S D NL L + LI+STGM +K + + + LLHC S YP
Sbjct: 135 KVASADLTNLPLLARLIATGKTLIVSTGMSTTEEIKAAAEFLDERKAGYVLLHCQSTYPA 194
Query: 729 PFEDCNL 749
+ +L
Sbjct: 195 ALHNIHL 201
>UniRef50_A7DQU2 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
N-acylneuraminate-9-phosphate synthase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 351
Score = 38.3 bits (85), Expect = 0.21
Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = +3
Query: 549 QIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDII-SSDHKQFCLLHCISAYP 725
++ S + N++ L++ A + P+I+STG + ++I + + L+ C S YP
Sbjct: 129 KVASFEINHIRLLEFLAKTQKPIIVSTGASTFKEIDFAINLIRKNGNDNIALMQCTSKYP 188
Query: 726 VPFEDCNLTVL 758
P + NL +
Sbjct: 189 CPIDSLNLKTI 199
>UniRef50_Q319P5 Cluster: Putative spore coat polysaccharide
biosynthesis protein E; n=1; Prochlorococcus marinus
str. MIT 9312|Rep: Putative spore coat polysaccharide
biosynthesis protein E - Prochlorococcus marinus (strain
MIT 9312)
Length = 521
Score = 37.9 bits (84), Expect = 0.27
Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 1/71 (1%)
Frame = +3
Query: 549 QIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK-QFCLLHCISAYP 725
+I S L+ A++ P+ ISTG + V IY + +F ++HC YP
Sbjct: 127 KIASCSCTEWSLLREVANQNKPVTISTGGRNLKEVDDIYSYFAHRIPYKFTIMHCCGIYP 186
Query: 726 VPFEDCNLTVL 758
P +D NL +
Sbjct: 187 APIKDLNLNTI 197
>UniRef50_A2BSE7 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. AS9601|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain AS9601)
Length = 356
Score = 37.9 bits (84), Expect = 0.27
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 1/68 (1%)
Frame = +3
Query: 549 QIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK-QFCLLHCISAYP 725
++ S D N + + AS +I+STG + +K +I S K LLHC+ YP
Sbjct: 132 KVASVDITNHILISQLASYGKDIILSTGASNLDEIKAAVSLIESKSKISPALLHCVVNYP 191
Query: 726 VPFEDCNL 749
+D NL
Sbjct: 192 TLDKDANL 199
>UniRef50_Q0YTS4 Cluster: N-acylneuraminate-9-phosphate synthase;
n=5; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Chlorobium ferrooxidans DSM 13031
Length = 354
Score = 36.3 bits (80), Expect = 0.83
Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVK-TIYDIISSDHKQ 692
+ L L +I S + ++ L A P+I+STG+ ++ + + ++ +
Sbjct: 125 ELLEQLGASAYKIASPEITHIPLLDKVARTGKPVILSTGLAALEDIELALATLRAAGSGE 184
Query: 693 FCLLHCISAYPVPFEDCNLTVL 758
LL C +AYP P E+ NL +
Sbjct: 185 IILLKCTTAYPAPIEEANLRTI 206
>UniRef50_Q0AN71 Cluster: N-acetylneuraminate synthase; n=1;
Maricaulis maris MCS10|Rep: N-acetylneuraminate synthase
- Maricaulis maris (strain MCS10)
Length = 305
Score = 35.1 bits (77), Expect = 1.9
Identities = 24/82 (29%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKT-IYDIISSDHKQ 692
+ + +L V +I SGD L+ + LI+STG V T + + S
Sbjct: 102 ELMESLGVKRYKIASGDLTFTPLLEALGATGKRLILSTGASYLDEVTTAVTTLTRSGCPH 161
Query: 693 FCLLHCISAYPVPFEDCNLTVL 758
LHC ++YP +ED NL+ +
Sbjct: 162 LTALHCAASYPPAWEDLNLSAI 183
>UniRef50_Q5A950 Cluster: Sterol 3-beta-glucosyltransferase; n=2;
Candida albicans|Rep: Sterol 3-beta-glucosyltransferase -
Candida albicans (Yeast)
Length = 1513
Score = 33.9 bits (74), Expect = 4.4
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
Frame = +1
Query: 316 FQKTCLG--EKFTKKYLERPYDNPNSWGKTYGE--HKSHLEFSDTQYRELFRYAQEVGIL 483
FQK L E+ K RP P WG + +K+ +E+SD++ RE+ +Y + I
Sbjct: 912 FQKVVLSVLERLHSKEGFRP--EPYQWGSNFEVELYKTRMEYSDSENREIQQYDNSIDIK 969
Query: 484 FTASAMDM 507
F ++M
Sbjct: 970 FAEKKIEM 977
>UniRef50_Q2IZW6 Cluster: N-acetylneuraminate synthase; n=1;
Rhodopseudomonas palustris HaA2|Rep: N-acetylneuraminate
synthase - Rhodopseudomonas palustris (strain HaA2)
Length = 332
Score = 33.5 bits (73), Expect = 5.9
Identities = 22/81 (27%), Positives = 35/81 (43%)
Frame = +3
Query: 516 DFLVNLKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQF 695
D L ++ V +I SG+ +N+ L A P+ +S+GM + + +
Sbjct: 104 DLLEDVGVAAYKIPSGEVSNIPLLSRIAQTGKPVFLSSGMSNWEELDAAVGALRG--SAL 161
Query: 696 CLLHCISAYPVPFEDCNLTVL 758
LL C S YP P E L +
Sbjct: 162 TLLQCTSKYPCPPEQVGLNAM 182
>UniRef50_A4U183 Cluster: N-acetylneuraminate synthase; n=1;
Magnetospirillum gryphiswaldense|Rep:
N-acetylneuraminate synthase - Magnetospirillum
gryphiswaldense
Length = 354
Score = 33.1 bits (72), Expect = 7.8
Identities = 31/108 (28%), Positives = 51/108 (47%), Gaps = 24/108 (22%)
Frame = +3
Query: 510 SFDFLVN-LKVPFIQIGSGDSNNLLFLKYAASKKIPLIISTGMVD--KTA---------- 650
S +FL++ L + I++GSG+ N L A + +I+STGM D +TA
Sbjct: 103 SLEFLIDRLGLDTIKLGSGELTNGPLLLQAGASGRNIILSTGMADLAETAQAVGVIGCGA 162
Query: 651 ----VKTIYDIISSDH-------KQFCLLHCISAYPVPFEDCNLTVLQ 761
T +I ++ H ++ LLHC + YP P + NL ++
Sbjct: 163 NGVLAPTESEIQAAAHCPSPDLIRRLTLLHCTTEYPAPMDQVNLRAME 210
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 777,523,740
Number of Sequences: 1657284
Number of extensions: 15844261
Number of successful extensions: 38213
Number of sequences better than 10.0: 78
Number of HSP's better than 10.0 without gapping: 36865
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 38167
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 63792713725
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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