Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= heS00507
(656 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_O97479 Cluster: CG1982-PA; n=17; Bilateria|Rep: CG1982-... 196 5e-49
UniRef50_Q6PGX2 Cluster: Zgc:63674; n=2; Danio rerio|Rep: Zgc:63... 169 5e-41
UniRef50_Q58D31 Cluster: Sorbitol dehydrogenase; n=8; Eukaryota|... 169 5e-41
UniRef50_Q00796 Cluster: Sorbitol dehydrogenase; n=35; Eumetazoa... 161 1e-38
UniRef50_Q02912 Cluster: Sorbitol dehydrogenase; n=1; Bombyx mor... 156 5e-37
UniRef50_Q7QAQ4 Cluster: ENSANGP00000011378; n=3; Culicidae|Rep:... 144 2e-33
UniRef50_UPI0000E46CC1 Cluster: PREDICTED: similar to SORD prote... 132 7e-30
UniRef50_Q16R00 Cluster: Alcohol dehydrogenase; n=3; Culicidae|R... 132 7e-30
UniRef50_Q67XB8 Cluster: Sorbitol dehydrogenase-like protein; n=... 131 1e-29
UniRef50_A1CFY8 Cluster: Xylitol dehydrogenase; n=22; Ascomycota... 127 2e-28
UniRef50_Q5KPZ2 Cluster: Sorbitol dehydrogenase, putative; n=1; ... 124 1e-27
UniRef50_Q06004 Cluster: Sorbitol dehydrogenase; n=5; Bacillales... 121 1e-26
UniRef50_Q0TT56 Cluster: L-iditol 2-dehydrogenase; n=3; Clostrid... 119 7e-26
UniRef50_A3TNY9 Cluster: Zinc-binding dehydrogenase; n=5; Actino... 117 2e-25
UniRef50_Q07786 Cluster: Sorbitol dehydrogenase 2; n=8; Saccharo... 116 7e-25
UniRef50_Q4WT02 Cluster: Xylitol dehydrogenase; n=8; Pezizomycot... 113 3e-24
UniRef50_Q5V6U8 Cluster: Zinc-binding dehydrogenase; n=1; Haloar... 113 4e-24
UniRef50_A5AB83 Cluster: Contig An08c0230, complete genome; n=9;... 112 6e-24
UniRef50_P36624 Cluster: Putative sorbitol dehydrogenase; n=1; S... 111 1e-23
UniRef50_P22144 Cluster: D-xylulose reductase; n=8; Saccharomyce... 108 1e-22
UniRef50_A1DBH5 Cluster: Alcohol dehydrogenase; n=3; Pezizomycot... 107 2e-22
UniRef50_Q1QUA2 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 106 5e-22
UniRef50_Q1J2J1 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 104 2e-21
UniRef50_Q89F70 Cluster: L-idonate 5-dehydrogenase; n=1; Bradyrh... 103 3e-21
UniRef50_Q0U204 Cluster: Putative uncharacterized protein; n=1; ... 103 3e-21
UniRef50_Q98D10 Cluster: Putative D-xylulose reductase; n=9; cel... 103 5e-21
UniRef50_Q5KPJ4 Cluster: Sorbitol dehydrogenase, putative; n=1; ... 102 7e-21
UniRef50_A2QU04 Cluster: Catalytic activity: L-iditol + NAD(+) =... 100 3e-20
UniRef50_Q4WT03 Cluster: L-arabinitol 4-dehydrogenase; n=5; Tric... 100 4e-20
UniRef50_Q59545 Cluster: D-xylulose reductase; n=36; Bacteria|Re... 100 4e-20
UniRef50_A3Q0B6 Cluster: Alcohol dehydrogenase GroES domain prot... 98 2e-19
UniRef50_A3GIE9 Cluster: Sorbitol dehydrogenase; n=2; Saccharomy... 98 2e-19
UniRef50_Q5K981 Cluster: L-iditol 2-dehydrogenase, putative; n=6... 97 3e-19
UniRef50_A1DK00 Cluster: Alcohol dehydrogenase; n=7; Pezizomycot... 95 1e-18
UniRef50_Q5WJ77 Cluster: Sorbitol dehydrogenase; n=1; Bacillus c... 94 2e-18
UniRef50_Q4PHJ5 Cluster: Putative uncharacterized protein; n=1; ... 94 2e-18
UniRef50_Q4PCL3 Cluster: Putative uncharacterized protein; n=1; ... 93 7e-18
UniRef50_A7II35 Cluster: Alcohol dehydrogenase GroES domain prot... 91 2e-17
UniRef50_A1CNK3 Cluster: Xylitol dehydrogenase XdhB, putative; n... 91 2e-17
UniRef50_P77280 Cluster: Uncharacterized zinc-type alcohol dehyd... 90 4e-17
UniRef50_Q5LQR4 Cluster: L-idonate 5-dehydrogenase; n=13; Alphap... 90 5e-17
UniRef50_A7F503 Cluster: Putative uncharacterized protein; n=1; ... 89 9e-17
UniRef50_A3DI68 Cluster: Alcohol dehydrogenase GroES-like protei... 87 3e-16
UniRef50_Q7S9B3 Cluster: Putative uncharacterized protein NCU070... 86 6e-16
UniRef50_Q0UEG3 Cluster: Putative uncharacterized protein; n=1; ... 86 6e-16
UniRef50_Q39JN7 Cluster: Zinc-containing alcohol dehydrogenase s... 85 1e-15
UniRef50_Q3ACJ3 Cluster: Sorbitol dehydrogenase; n=1; Carboxydot... 84 2e-15
UniRef50_Q2UHR2 Cluster: Sorbitol dehydrogenase; n=8; Ascomycota... 84 2e-15
UniRef50_Q8ELG9 Cluster: Sorbitol dehydrogenase; n=2; Bacillacea... 84 3e-15
UniRef50_A1WNS6 Cluster: Alcohol dehydrogenase GroES domain prot... 84 3e-15
UniRef50_A6X6E2 Cluster: Alcohol dehydrogenase GroES domain prot... 83 8e-15
UniRef50_A6W685 Cluster: Alcohol dehydrogenase zinc-binding doma... 81 2e-14
UniRef50_A6W9X6 Cluster: Alcohol dehydrogenase GroES domain prot... 81 3e-14
UniRef50_A0GHL5 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 80 4e-14
UniRef50_A5I7E3 Cluster: Sorbitol dehydrogenase; n=7; Clostridiu... 80 5e-14
UniRef50_A0JXR0 Cluster: Alcohol dehydrogenase, zinc-binding dom... 80 5e-14
UniRef50_A6BDE4 Cluster: Putative uncharacterized protein; n=2; ... 79 1e-13
UniRef50_Q5KAN3 Cluster: Xylitol dehydrogenase, putative; n=1; F... 77 3e-13
UniRef50_Q188T6 Cluster: Putative sugar-phosphate dehydrogenase;... 76 7e-13
UniRef50_A6LBP5 Cluster: Putative uncharacterized protein; n=1; ... 76 9e-13
UniRef50_Q5KJK1 Cluster: Zinc-binding dehydrogenase, putative; n... 75 1e-12
UniRef50_Q9S270 Cluster: Putative zinc-binding alcohol dehydroge... 75 2e-12
UniRef50_Q930C9 Cluster: IdnD L-idonate 5-dehydrogenase; n=4; Al... 75 2e-12
UniRef50_UPI0000DD8301 Cluster: PREDICTED: similar to Sorbitol d... 73 5e-12
UniRef50_A4FJI0 Cluster: Putative zinc-binding alcohol dehydroge... 73 5e-12
UniRef50_A3PQM0 Cluster: Alcohol dehydrogenase GroES domain prot... 73 5e-12
UniRef50_Q5KJG0 Cluster: Xylitol dehydrogenase, putative; n=1; F... 72 1e-11
UniRef50_Q8EL78 Cluster: Alcohol dehydrogenase; n=1; Oceanobacil... 71 2e-11
UniRef50_Q7SHA1 Cluster: Putative uncharacterized protein NCU019... 70 4e-11
UniRef50_A0V2V9 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 70 6e-11
UniRef50_A5JSX4 Cluster: Zinc-containing alcohol dehydrogenase; ... 69 1e-10
UniRef50_A1UPQ2 Cluster: Alcohol dehydrogenase GroES domain prot... 69 1e-10
UniRef50_Q01VI1 Cluster: Alcohol dehydrogenase GroES domain prot... 69 1e-10
UniRef50_Q4LED8 Cluster: Dehydrogenase; n=1; uncultured crenarch... 69 1e-10
UniRef50_Q01PH7 Cluster: Alcohol dehydrogenase GroES domain prot... 68 2e-10
UniRef50_P39346 Cluster: L-idonate 5-dehydrogenase; n=17; Gammap... 68 2e-10
UniRef50_A3DCE7 Cluster: Alcohol dehydrogenase GroES-like protei... 68 2e-10
UniRef50_A1SCW8 Cluster: Alcohol dehydrogenase, zinc-binding dom... 68 2e-10
UniRef50_A5FZ32 Cluster: Alcohol dehydrogenase GroES domain prot... 67 3e-10
UniRef50_A3S6P0 Cluster: L-threonine 3-dehydrogenase; n=2; Bacte... 67 3e-10
UniRef50_Q88S92 Cluster: L-iditol 2-dehydrogenase; n=7; Firmicut... 67 4e-10
UniRef50_A0QWX1 Cluster: Oxidoreductase, zinc-binding dehydrogen... 67 4e-10
UniRef50_Q5K658 Cluster: Sorbitol dehydrogenase; n=2; Dikarya|Re... 67 4e-10
UniRef50_A2R6Z1 Cluster: Catalytic activity: L-iditol + NAD(+) <... 67 4e-10
UniRef50_Q5LVU9 Cluster: Sorbitol dehydrogenase, putative; n=13;... 66 7e-10
UniRef50_A5V1N3 Cluster: Alcohol dehydrogenase GroES domain prot... 66 7e-10
UniRef50_Q8ZJN2 Cluster: L-threonine 3-dehydrogenase; n=41; Bact... 66 9e-10
UniRef50_Q6NDJ8 Cluster: Putative Zn-binding dehydrogenase; n=1;... 65 1e-09
UniRef50_A4XEZ1 Cluster: Alcohol dehydrogenase, zinc-binding dom... 65 1e-09
UniRef50_Q5B6Y0 Cluster: Putative uncharacterized protein; n=1; ... 65 1e-09
UniRef50_A5D1M5 Cluster: Threonine dehydrogenase and related Zn-... 65 2e-09
UniRef50_Q9VDQ9 Cluster: CG4836-PC, isoform C; n=4; Eukaryota|Re... 65 2e-09
UniRef50_Q1HPY0 Cluster: Zinc-containing alcohol dehydrogenase; ... 65 2e-09
UniRef50_Q46NN2 Cluster: Zinc-containing alcohol dehydrogenase s... 64 2e-09
UniRef50_A4FHA7 Cluster: Zinc-binding dehydrogenase; n=1; Saccha... 64 2e-09
UniRef50_A1SFU6 Cluster: Alcohol dehydrogenase, zinc-binding dom... 64 3e-09
UniRef50_A0TC93 Cluster: Alcohol dehydrogenase GroES-like; n=15;... 64 3e-09
UniRef50_A0JVX4 Cluster: Alcohol dehydrogenase GroES domain prot... 64 4e-09
UniRef50_Q24T43 Cluster: Putative uncharacterized protein; n=1; ... 63 5e-09
UniRef50_Q9KGB7 Cluster: Sorbitol dehydrogenase; n=28; Bacillale... 63 7e-09
UniRef50_Q9UAT1 Cluster: Putative uncharacterized protein; n=1; ... 63 7e-09
UniRef50_A4XHJ7 Cluster: Alcohol dehydrogenase GroES domain prot... 62 9e-09
UniRef50_Q0UBF8 Cluster: Putative uncharacterized protein; n=1; ... 62 9e-09
UniRef50_Q1Q2R9 Cluster: Similar to sorbitol dehydrogenase; n=1;... 62 1e-08
UniRef50_Q9RTU4 Cluster: L-threonine 3-dehydrogenase; n=178; Bac... 62 1e-08
UniRef50_Q81V29 Cluster: Alcohol dehydrogenase, zinc-containing;... 62 2e-08
UniRef50_A1D0R7 Cluster: Alcohol dehydrogenase; n=2; Trichocomac... 62 2e-08
UniRef50_Q38ZV8 Cluster: Zinc-containing alcohol dehydrogenase s... 61 2e-08
UniRef50_Q12E06 Cluster: Alcohol dehydrogenase GroES-like; n=2; ... 61 2e-08
UniRef50_A1HSQ8 Cluster: Alcohol dehydrogenase GroES domain prot... 61 2e-08
UniRef50_A0IRE9 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 61 2e-08
UniRef50_A3I7D7 Cluster: Zinc-containing alcohol dehydrogenase, ... 61 3e-08
UniRef50_A0JVZ1 Cluster: Alcohol dehydrogenase GroES domain prot... 60 3e-08
UniRef50_Q927H5 Cluster: Lin2813 protein; n=16; Firmicutes|Rep: ... 60 5e-08
UniRef50_Q5WC08 Cluster: Galactitol-1-phosphate 5-dehydrogenase;... 60 5e-08
UniRef50_A5ZM46 Cluster: Putative uncharacterized protein; n=2; ... 60 5e-08
UniRef50_A1RYE2 Cluster: Alcohol dehydrogenase GroES domain prot... 60 5e-08
UniRef50_Q57517 Cluster: Uncharacterized zinc-type alcohol dehyd... 60 5e-08
UniRef50_O58389 Cluster: Probable L-threonine 3-dehydrogenase; n... 60 5e-08
UniRef50_Q65L05 Cluster: YjmD; n=1; Bacillus licheniformis ATCC ... 60 6e-08
UniRef50_Q5V6V7 Cluster: Zinc-binding dehydrogenase; n=1; Haloar... 60 6e-08
UniRef50_Q025V7 Cluster: Alcohol dehydrogenase GroES domain prot... 59 8e-08
UniRef50_A0UVK1 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 59 8e-08
UniRef50_Q9RS48 Cluster: Alcohol dehydrogenase, zinc-containing;... 59 1e-07
UniRef50_Q65L02 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07
UniRef50_Q1PUQ4 Cluster: Similar to zinc-containing dehydrogenas... 59 1e-07
UniRef50_Q9K5Y6 Cluster: L-iditol 2-dehydrogenase; n=8; Bacteria... 58 1e-07
UniRef50_Q8ELI9 Cluster: Sorbitol dehydrogenase; n=2; Bacillacea... 58 1e-07
UniRef50_Q1ARQ8 Cluster: Alcohol dehydrogenase GroES-like protei... 58 1e-07
UniRef50_A0NKD6 Cluster: Zc-binding dehydrogenase; n=3; Oenococc... 58 1e-07
UniRef50_Q3A2I8 Cluster: Putative zinc-containing alcohol dehydr... 58 2e-07
UniRef50_A6VRA2 Cluster: Alcohol dehydrogenase GroES domain prot... 58 2e-07
UniRef50_A4J9K3 Cluster: Alcohol dehydrogenase GroES domain prot... 58 2e-07
UniRef50_A0UVE8 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 58 2e-07
UniRef50_Q9HWM8 Cluster: 2,3-butanediol dehydrogenase; n=24; Pro... 58 2e-07
UniRef50_Q7UT38 Cluster: Zinc-type alcohol dehydrogenase; n=1; P... 58 2e-07
UniRef50_Q7CVQ9 Cluster: AGR_L_281p; n=7; Alphaproteobacteria|Re... 58 2e-07
UniRef50_A4XUM5 Cluster: Alcohol dehydrogenase GroES domain prot... 58 2e-07
UniRef50_Q8KQG6 Cluster: Mannitol dehydrogenase; n=12; Bacteria|... 57 3e-07
UniRef50_Q1AZ51 Cluster: Alcohol dehydrogenase GroES-like protei... 57 3e-07
UniRef50_A5D5N1 Cluster: Threonine dehydrogenase and related Zn-... 57 3e-07
UniRef50_A1UG38 Cluster: Alcohol dehydrogenase GroES domain prot... 57 3e-07
UniRef50_Q5YU97 Cluster: Putative dehydrogenase; n=1; Nocardia f... 57 4e-07
UniRef50_A3Q0B4 Cluster: Alcohol dehydrogenase GroES domain prot... 57 4e-07
UniRef50_A2UF68 Cluster: Alcohol dehydrogenase GroES domain prot... 57 4e-07
UniRef50_Q97TZ4 Cluster: Sorbitol dehydrogenase; n=4; Sulfolobac... 57 4e-07
UniRef50_Q72U55 Cluster: Zinc binding dehydrogenase; n=4; Leptos... 56 6e-07
UniRef50_Q1IQV5 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 56 6e-07
UniRef50_Q3B3S5 Cluster: Alcohol dehydrogenase, zinc-containing;... 56 7e-07
UniRef50_Q5HLF5 Cluster: Sorbitol dehydrogenase, putative; n=10;... 56 1e-06
UniRef50_Q565X2 Cluster: 6-hydroxycylohex-1-ene-1-carboxyl-CoA d... 56 1e-06
UniRef50_Q2AGV2 Cluster: Zinc-containing alcohol dehydrogenase s... 56 1e-06
UniRef50_A4AMR5 Cluster: Zn-dependent alcohol dehydrogenase; n=2... 56 1e-06
UniRef50_A3U1C0 Cluster: Threonine 3-dehydrogenase; n=1; Oceanic... 56 1e-06
UniRef50_Q0CVZ1 Cluster: Putative uncharacterized protein; n=1; ... 56 1e-06
UniRef50_UPI00015970BD Cluster: GutB1; n=1; Bacillus amyloliquef... 55 1e-06
UniRef50_Q987C5 Cluster: Alcohol dehydrogenase; n=4; Rhizobiales... 55 1e-06
UniRef50_Q8DK96 Cluster: Tll0970 protein; n=6; Cyanobacteria|Rep... 55 1e-06
UniRef50_Q0RW76 Cluster: Probable Zn-containing alcohol dehydrog... 55 1e-06
UniRef50_Q5HRD6 Cluster: Alcohol dehydrogenase; n=106; Bacteria|... 55 1e-06
UniRef50_Q3IVK2 Cluster: Zinc-containing alcohol dehydrogenase; ... 55 2e-06
UniRef50_O35045 Cluster: Zinc-containing alcohol dehydrogenase; ... 55 2e-06
UniRef50_Q59715 Cluster: Benzyl alcohol dehydrogenase II; n=5; P... 54 2e-06
UniRef50_Q5BBC2 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-06
UniRef50_UPI000050F926 Cluster: COG1063: Threonine dehydrogenase... 54 3e-06
UniRef50_Q9RKG0 Cluster: Putative dehydrogenase; n=1; Streptomyc... 54 3e-06
UniRef50_Q92YT8 Cluster: Putative; n=2; Alphaproteobacteria|Rep:... 54 3e-06
UniRef50_Q0LSY1 Cluster: Alcohol dehydrogenase, zinc-binding:Alc... 54 3e-06
UniRef50_A5VBI0 Cluster: Alcohol dehydrogenase, zinc-binding dom... 54 3e-06
UniRef50_A1R5Y9 Cluster: L-threonine 3-dehydrogenase; n=1; Arthr... 54 3e-06
UniRef50_UPI000038E1A4 Cluster: hypothetical protein Faci_030008... 54 4e-06
UniRef50_Q8DIZ5 Cluster: Sorbitol dehydrogenase; n=6; Cyanobacte... 54 4e-06
UniRef50_Q83GG5 Cluster: Zinc-type alcohol dehydrogenase; n=3; A... 54 4e-06
UniRef50_Q2RG84 Cluster: Alcohol dehydrogenase superfamily, zinc... 54 4e-06
UniRef50_Q44P31 Cluster: Zinc-containing alcohol dehydrogenase s... 54 4e-06
UniRef50_A5WI29 Cluster: Alcohol dehydrogenase, zinc-binding dom... 54 4e-06
UniRef50_A1UQB9 Cluster: Alcohol dehydrogenase GroES domain prot... 54 4e-06
UniRef50_Q8Y414 Cluster: Lmo2663 protein; n=14; Firmicutes|Rep: ... 53 5e-06
UniRef50_Q829Q5 Cluster: Putative zinc-binding dehydrogenase; n=... 53 5e-06
UniRef50_Q1IQV6 Cluster: Alcohol dehydrogenase GroES-like; n=2; ... 53 5e-06
UniRef50_A4XGJ9 Cluster: Alcohol dehydrogenase, zinc-binding dom... 53 5e-06
UniRef50_Q98CF7 Cluster: 2,3-butanediol dehydrogenase; n=5; Rhiz... 53 7e-06
UniRef50_Q39TG2 Cluster: Alcohol dehydrogenase superfamily, zinc... 53 7e-06
UniRef50_A0NL69 Cluster: Sorbitol dehydrogenase; n=2; Oenococcus... 53 7e-06
UniRef50_A0LL41 Cluster: Alcohol dehydrogenase GroES domain prot... 53 7e-06
UniRef50_A0JVW4 Cluster: Alcohol dehydrogenase GroES domain prot... 53 7e-06
UniRef50_A1DNE9 Cluster: Alcohol dehydrogenase; n=4; Trichocomac... 53 7e-06
UniRef50_Q46N56 Cluster: Zinc-containing alcohol dehydrogenase s... 52 9e-06
UniRef50_A7B0E7 Cluster: Putative uncharacterized protein; n=1; ... 52 9e-06
UniRef50_A5D4M1 Cluster: Zn-dependent alcohol dehydrogenases; n=... 52 9e-06
UniRef50_UPI00015BC9A2 Cluster: UPI00015BC9A2 related cluster; n... 52 1e-05
UniRef50_Q7US13 Cluster: Probable zinc-type alcohol dehydrogenas... 52 1e-05
UniRef50_Q0RVL1 Cluster: Zn-dependent alcohol dehydrogenase; n=1... 52 1e-05
UniRef50_A6NT70 Cluster: Putative uncharacterized protein; n=1; ... 52 1e-05
UniRef50_P14940 Cluster: Alcohol dehydrogenase; n=31; cellular o... 52 1e-05
UniRef50_UPI0000553E21 Cluster: Zinc-containing alcohol dehydrog... 52 2e-05
UniRef50_Q8UB54 Cluster: Zinc-binding dehydrogenase; n=3; Rhizob... 52 2e-05
UniRef50_A4QH16 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_A3JMN6 Cluster: Dehydrogenase; n=4; Bacteria|Rep: Dehyd... 52 2e-05
UniRef50_Q8R7K0 Cluster: L-threonine 3-dehydrogenase; n=3; cellu... 52 2e-05
UniRef50_UPI0000498928 Cluster: zinc-containing alcohol dehydrog... 51 2e-05
UniRef50_Q63FG9 Cluster: Zinc-containing alcohol dehydrogenase; ... 51 2e-05
UniRef50_Q1A676 Cluster: Alcohol dehydrogenase; n=4; Bacteria|Re... 51 2e-05
UniRef50_A5V690 Cluster: Alcohol dehydrogenase GroES domain prot... 51 2e-05
UniRef50_A4QUV6 Cluster: Putative uncharacterized protein; n=2; ... 51 2e-05
UniRef50_Q97NH4 Cluster: Alcohol dehydrogenase, zinc-containing;... 51 3e-05
UniRef50_Q3ZWK2 Cluster: Alcohol dehydrogenase, zinc-containing;... 51 3e-05
UniRef50_Q1QWS0 Cluster: Alcohol dehydrogenase GroES-like protei... 51 3e-05
UniRef50_Q1IJN0 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 51 3e-05
UniRef50_Q11VP8 Cluster: Zinc-type alcohol dehydrogenase; n=2; S... 51 3e-05
UniRef50_A0JVV9 Cluster: Alcohol dehydrogenase GroES domain prot... 51 3e-05
UniRef50_P38105 Cluster: Starvation-sensing protein rspB; n=36; ... 51 3e-05
UniRef50_Q62AB8 Cluster: Oxidoreductase, zinc-binding dehydrogen... 50 4e-05
UniRef50_A5FCD7 Cluster: Alcohol dehydrogenase, zinc-binding dom... 50 4e-05
UniRef50_Q4PP82 Cluster: Putative zinc-containing alcohol dehydr... 50 4e-05
UniRef50_Q67N85 Cluster: L-threonine 3-dehydrogenase; n=10; Bact... 50 4e-05
UniRef50_Q62CY1 Cluster: Alcohol dehydrogenase, zinc-containing;... 50 5e-05
UniRef50_Q1J6P8 Cluster: Zn-dependent alcohol dehydrogenase; n=1... 50 5e-05
UniRef50_Q1AVM7 Cluster: Alcohol dehydrogenase GroES-like protei... 50 5e-05
UniRef50_A6VLA0 Cluster: Alcohol dehydrogenase GroES domain prot... 50 5e-05
UniRef50_A1SLI2 Cluster: Alcohol dehydrogenase GroES domain prot... 50 5e-05
UniRef50_A0JVX5 Cluster: Alcohol dehydrogenase, zinc-binding dom... 50 5e-05
UniRef50_Q5K7P7 Cluster: (R,R)-butanediol dehydrogenase, putativ... 50 5e-05
UniRef50_Q62K93 Cluster: Oxidoreductase, zinc-binding dehydrogen... 50 6e-05
UniRef50_Q2LXU3 Cluster: 6-hydroxycyclohex-1-ene-1-carboxyl-CoA ... 50 6e-05
UniRef50_A6AJT3 Cluster: Alcohol dehydrogenase, zinc-containing;... 50 6e-05
UniRef50_A4FB48 Cluster: Putative uncharacterized protein; n=1; ... 50 6e-05
UniRef50_A0QTC9 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;... 50 6e-05
UniRef50_Q00SV0 Cluster: COG1064: Zn-dependent alcohol dehydroge... 50 6e-05
UniRef50_A0V7I1 Cluster: Alcohol dehydrogenase GroES-like; n=2; ... 49 9e-05
UniRef50_A0LRZ3 Cluster: Alcohol dehydrogenase GroES domain prot... 49 9e-05
UniRef50_Q4LED7 Cluster: Sorbitol dehydrogenase; n=1; uncultured... 49 9e-05
UniRef50_P77360 Cluster: Uncharacterized zinc-type alcohol dehyd... 49 9e-05
UniRef50_O45687 Cluster: Alcohol dehydrogenase 2; n=3; Caenorhab... 49 9e-05
UniRef50_Q8A1P2 Cluster: Sorbitol dehydrogenase; n=4; Bacteroide... 49 1e-04
UniRef50_A6PRU8 Cluster: Alcohol dehydrogenase GroES domain prot... 49 1e-04
UniRef50_A3DME0 Cluster: Alcohol dehydrogenase GroES domain prot... 49 1e-04
UniRef50_A0RXG2 Cluster: Zn-dependent alcohol dehydrogenase; n=2... 49 1e-04
UniRef50_P39400 Cluster: Uncharacterized zinc-type alcohol dehyd... 49 1e-04
UniRef50_UPI00015B5FCF Cluster: PREDICTED: similar to putative z... 48 1e-04
UniRef50_Q7U377 Cluster: Putative Zinc-binding dehydrogenase; n=... 48 1e-04
UniRef50_Q6MJG4 Cluster: Putative alcohol dehydrogenase I; n=1; ... 48 1e-04
UniRef50_Q5BFT1 Cluster: Putative uncharacterized protein; n=1; ... 48 1e-04
UniRef50_Q7UU62 Cluster: Sorbitol dehydrogenase; n=1; Pirellula ... 48 2e-04
UniRef50_Q2LQ73 Cluster: Zinc-binding dehydrogenase; n=2; Bacter... 48 2e-04
UniRef50_A7NMA5 Cluster: Alcohol dehydrogenase GroES domain prot... 48 2e-04
UniRef50_A7HAS7 Cluster: Alcohol dehydrogenase GroES domain prot... 48 2e-04
UniRef50_A1K6Y3 Cluster: Putative alcohol dehydrogenase; n=1; Az... 48 2e-04
UniRef50_A0QZF0 Cluster: Oxidoreductase, zinc-binding dehydrogen... 48 2e-04
UniRef50_Q6BC32 Cluster: Glycerol dehydrogenase; n=3; Saccharomy... 48 2e-04
UniRef50_A2R610 Cluster: Catalytic activity:; n=5; Trichocomacea... 48 2e-04
UniRef50_A3H9A2 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 48 2e-04
UniRef50_Q9WYP3 Cluster: Alcohol dehydrogenase, zinc-containing;... 48 3e-04
UniRef50_Q7NLF7 Cluster: Gll1167 protein; n=4; Bacteria|Rep: Gll... 48 3e-04
UniRef50_Q74FN3 Cluster: Alcohol dehydrogenase, zinc-containing;... 48 3e-04
UniRef50_Q6AAC4 Cluster: Alcohol dehydrogenase; n=1; Propionibac... 48 3e-04
UniRef50_A7H7S9 Cluster: Alcohol dehydrogenase GroES domain prot... 48 3e-04
UniRef50_A5N5N6 Cluster: Zn-dependent dehydrogenase; n=1; Clostr... 48 3e-04
UniRef50_A1W2W1 Cluster: Alcohol dehydrogenase GroES domain prot... 48 3e-04
UniRef50_A0QZI7 Cluster: Aryl-alcohol dehydrogenase; n=1; Mycoba... 48 3e-04
UniRef50_Q5B536 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04
UniRef50_Q97YM2 Cluster: Alcohol dehydrogenase; n=2; Sulfolobus ... 48 3e-04
UniRef50_Q1LNT3 Cluster: Alcohol dehydrogenase GroES-like protei... 47 3e-04
UniRef50_Q0S7E4 Cluster: Possible alcohol dehydrogenase; n=2; No... 47 3e-04
UniRef50_A1BBU7 Cluster: Alcohol dehydrogenase, zinc-binding dom... 47 3e-04
UniRef50_A0LGB6 Cluster: Alcohol dehydrogenase GroES domain prot... 47 3e-04
UniRef50_Q6BC30 Cluster: Dihydroxyacetone reductase; n=11; cellu... 47 3e-04
UniRef50_P07246 Cluster: Alcohol dehydrogenase III, mitochondria... 47 3e-04
UniRef50_A6LR91 Cluster: Alcohol dehydrogenase GroES domain prot... 47 5e-04
UniRef50_A5V832 Cluster: Alcohol dehydrogenase GroES domain prot... 47 5e-04
UniRef50_A7RKY5 Cluster: Predicted protein; n=1; Nematostella ve... 47 5e-04
UniRef50_Q2U8M8 Cluster: Threonine dehydrogenase and related Zn-... 47 5e-04
UniRef50_Q0TXS2 Cluster: Putative uncharacterized protein; n=2; ... 47 5e-04
UniRef50_A1C7T1 Cluster: Alcohol dehydrogenase, zinc-containing;... 47 5e-04
UniRef50_Q9HJX2 Cluster: Alcohol dehydrogenase related protein; ... 47 5e-04
UniRef50_Q5V3L1 Cluster: Sorbitol dehydrogenase; n=4; Halobacter... 47 5e-04
UniRef50_P0A9S4 Cluster: Galactitol-1-phosphate 5-dehydrogenase;... 47 5e-04
UniRef50_Q9Z9U1 Cluster: Sorbitol dehydrogenase; n=14; Bacillale... 47 5e-04
UniRef50_Q8EMM7 Cluster: Dehydrogenase; n=1; Oceanobacillus ihey... 46 6e-04
UniRef50_Q2G759 Cluster: GroES-related; n=1; Novosphingobium aro... 46 6e-04
UniRef50_Q7BKE4 Cluster: Predicted Zn-dependent alcohol dehydrog... 46 6e-04
UniRef50_A5ZML1 Cluster: Putative uncharacterized protein; n=1; ... 46 6e-04
UniRef50_A0QS68 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;... 46 6e-04
UniRef50_Q5A958 Cluster: Potential secondary alcohol dehydrogena... 46 6e-04
UniRef50_A6S0I2 Cluster: Putative uncharacterized protein; n=1; ... 46 6e-04
UniRef50_Q5YR32 Cluster: Putative dehydrogenase; n=1; Nocardia f... 46 8e-04
UniRef50_Q7D7T9 Cluster: Zinc-binding dehydrogenase; n=15; Mycob... 46 8e-04
UniRef50_Q3W5D6 Cluster: Zinc-containing alcohol dehydrogenase s... 46 8e-04
UniRef50_Q1PZD2 Cluster: Strong similarity to L-threonine dehydr... 46 8e-04
UniRef50_Q1ARB8 Cluster: Alcohol dehydrogenase, zinc-binding pro... 46 8e-04
UniRef50_Q0SAT0 Cluster: Zn-containing alcohol dehdyrogenase; n=... 46 8e-04
UniRef50_A6YFI0 Cluster: Zinc-dependent dehydrogenase; n=1; Arth... 46 8e-04
UniRef50_A0HHZ1 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 46 8e-04
UniRef50_Q0UZS7 Cluster: Putative uncharacterized protein; n=1; ... 46 8e-04
UniRef50_A1D1F8 Cluster: Alcohol dehydrogenase; n=3; Pezizomycot... 46 8e-04
UniRef50_Q96XE0 Cluster: NAD-dependent alcohol dehydrogenase; n=... 46 8e-04
UniRef50_Q8EVN7 Cluster: NADP-dependent alcohol dehydrogenase; n... 46 0.001
UniRef50_Q6AA39 Cluster: Zinc-binding dehydrogenase; n=1; Propio... 46 0.001
UniRef50_Q3W6B4 Cluster: Zinc-containing alcohol dehydrogenase s... 46 0.001
UniRef50_Q15TG4 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 46 0.001
UniRef50_Q14DY9 Cluster: Alcohol dehydrogenase; n=1; Pseudomonas... 46 0.001
UniRef50_A5FWT0 Cluster: Alcohol dehydrogenase GroES domain prot... 46 0.001
UniRef50_A5CZI6 Cluster: Threonine dehydrogenase and related Zn-... 46 0.001
UniRef50_A1RCH0 Cluster: Putative alcohol dehydrogenase; n=2; Ar... 46 0.001
UniRef50_A6RPM4 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_Q5V676 Cluster: Alcohol dehydrogenase; n=7; cellular or... 46 0.001
UniRef50_Q3MCP8 Cluster: Zinc-containing alcohol dehydrogenase s... 45 0.001
UniRef50_Q0SJ82 Cluster: Possible alcohol dehydrogenase; n=13; c... 45 0.001
UniRef50_A6X5V4 Cluster: Alcohol dehydrogenase zinc-binding doma... 45 0.001
UniRef50_A2QFZ8 Cluster: Catalytic activity: alcohol dehydrogena... 45 0.001
UniRef50_Q0SDC0 Cluster: Zn-binding alcohol dehydrogenase; n=1; ... 45 0.002
UniRef50_A6M074 Cluster: Alcohol dehydrogenase GroES domain prot... 45 0.002
UniRef50_A6EYW6 Cluster: Zinc-containing alcohol dehydrogenase s... 45 0.002
UniRef50_A4RNL2 Cluster: Putative uncharacterized protein; n=3; ... 45 0.002
UniRef50_A1DJP7 Cluster: Alcohol dehydrogenase, putative; n=5; T... 45 0.002
UniRef50_Q6NC01 Cluster: Possible alcohol dehydrogenase class II... 44 0.002
UniRef50_Q6ABT0 Cluster: Alcohol dehydrogenase; n=1; Propionibac... 44 0.002
UniRef50_Q2KCX6 Cluster: Probable zinc-type alcohol dehydrogenas... 44 0.002
UniRef50_Q0S5T4 Cluster: Alcohol dehydrogenase; n=1; Rhodococcus... 44 0.002
UniRef50_Q0K0E7 Cluster: Zinc-type alcohol dehydrogenase adhd; n... 44 0.002
UniRef50_A5ZSK2 Cluster: Putative uncharacterized protein; n=1; ... 44 0.002
UniRef50_A4XA81 Cluster: Alcohol dehydrogenase GroES domain prot... 44 0.002
UniRef50_Q0UBV8 Cluster: Putative uncharacterized protein; n=2; ... 44 0.002
UniRef50_A7EYS9 Cluster: Putative uncharacterized protein; n=1; ... 44 0.002
UniRef50_A0RV95 Cluster: L-iditol 2-dehydrogenase/threonine dehy... 44 0.002
UniRef50_P09347 Cluster: 5-exo-alcohol dehydrogenase; n=4; Prote... 44 0.002
UniRef50_P07327 Cluster: Alcohol dehydrogenase 1A; n=1281; cellu... 44 0.002
UniRef50_Q9A414 Cluster: Alcohol dehydrogenase class III; n=8; P... 44 0.003
UniRef50_Q0RVY2 Cluster: Dehydrogenase; n=1; Rhodococcus sp. RHA... 44 0.003
UniRef50_A5V7S4 Cluster: Alcohol dehydrogenase, zinc-binding dom... 44 0.003
UniRef50_A0FZB5 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 44 0.003
UniRef50_Q5KJW4 Cluster: Zinc-type alcohol dehydrogenase, putati... 44 0.003
UniRef50_Q1DLA7 Cluster: Alcohol dehydrogenase; n=2; Eurotiomyce... 44 0.003
UniRef50_A5DYS7 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003
UniRef50_UPI000051A87A Cluster: PREDICTED: similar to R04B5.5; n... 44 0.004
UniRef50_Q47QG1 Cluster: Alcohol dehydrogenase class III; n=1; T... 44 0.004
UniRef50_A6WA66 Cluster: Alcohol dehydrogenase zinc-binding doma... 44 0.004
UniRef50_A5IYL7 Cluster: Alcohol dehydrogenase; n=2; Mycoplasma ... 44 0.004
UniRef50_A1CC26 Cluster: Alcohol dehydrogenase; n=4; cellular or... 44 0.004
UniRef50_Q8TTM5 Cluster: Zinc-binding alcohol dehydrogenase; n=3... 44 0.004
UniRef50_Q8PYV2 Cluster: Glutathione-independent formaldehyde de... 44 0.004
UniRef50_A3MVR8 Cluster: Alcohol dehydrogenase GroES domain prot... 44 0.004
UniRef50_Q9HTE3 Cluster: Glutathione-independent formaldehyde de... 44 0.004
UniRef50_Q2J7M3 Cluster: Alcohol dehydrogenase GroES-like; n=3; ... 43 0.006
UniRef50_Q7D3N5 Cluster: AGR_pAT_280p; n=3; Alphaproteobacteria|... 43 0.006
UniRef50_Q2HBT9 Cluster: Putative uncharacterized protein; n=1; ... 43 0.006
UniRef50_Q8ZU64 Cluster: Alcohol dehydrogenase; n=5; Thermoprote... 43 0.006
UniRef50_A3H5I8 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 43 0.006
UniRef50_Q9WYD4 Cluster: Alcohol dehydrogenase, zinc-containing;... 43 0.007
UniRef50_Q88TC0 Cluster: Aryl-alcohol dehydrogenase; n=6; Lactob... 43 0.007
UniRef50_Q2G9N3 Cluster: Alcohol dehydrogenase, zinc-containing;... 43 0.007
UniRef50_A1W5R7 Cluster: Alcohol dehydrogenase GroES domain prot... 43 0.007
UniRef50_A1SJ83 Cluster: Alcohol dehydrogenase GroES domain prot... 43 0.007
UniRef50_A0QZV9 Cluster: Alcohol dehydrogenase B; n=1; Mycobacte... 43 0.007
UniRef50_A0NJ16 Cluster: L-iditol 2-dehydrogenase; n=5; Bacteria... 43 0.007
UniRef50_A0IUR9 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 43 0.007
UniRef50_Q7PU31 Cluster: ENSANGP00000000280; n=3; cellular organ... 43 0.007
UniRef50_Q5KF98 Cluster: Alcohol dehydrogenase, putative; n=1; F... 43 0.007
UniRef50_Q4P3P9 Cluster: Putative uncharacterized protein; n=1; ... 43 0.007
UniRef50_Q0CUL9 Cluster: Putative uncharacterized protein; n=2; ... 43 0.007
UniRef50_Q97ZV3 Cluster: Alcohol dehydrogenase; n=7; Thermoprote... 43 0.007
UniRef50_Q6KZL8 Cluster: Alcohol dehydrogenase; n=1; Picrophilus... 43 0.007
UniRef50_Q5V607 Cluster: Zinc-binding dehydrogenase; n=5; Haloba... 43 0.007
UniRef50_A3H8A1 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 43 0.007
UniRef50_Q7NR39 Cluster: Probable glutathione-dependent aldehyde... 42 0.010
UniRef50_Q5SL93 Cluster: Zinc-binding dehydrogenase; n=2; Thermu... 42 0.010
UniRef50_Q53929 Cluster: ORF4 protein; n=2; Streptomyces coelico... 42 0.010
UniRef50_Q3WAW5 Cluster: Zinc-containing alcohol dehydrogenase s... 42 0.010
UniRef50_Q1GKP3 Cluster: Alcohol dehydrogenase GroES-like protei... 42 0.010
UniRef50_A6M049 Cluster: Alcohol dehydrogenase GroES domain prot... 42 0.010
UniRef50_A7SKJ4 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.010
UniRef50_Q97VW0 Cluster: Alcohol dehydrogenase; n=7; Thermoprote... 42 0.010
UniRef50_Q8ZVZ5 Cluster: Alcohol dehydrogenase; n=1; Pyrobaculum... 42 0.010
UniRef50_P77316 Cluster: Uncharacterized zinc-type alcohol dehyd... 42 0.010
UniRef50_P39849 Cluster: Aryl-alcohol dehydrogenase; n=33; Bacte... 42 0.010
UniRef50_Q98GG6 Cluster: L-iditol 2-dehydrogenase; n=5; Alphapro... 42 0.013
UniRef50_Q8Z6Z4 Cluster: Starvation sensing protein RspB; n=1; S... 42 0.013
UniRef50_Q577J1 Cluster: Alcohol dehydrogenase, zinc-containing;... 42 0.013
UniRef50_O06012 Cluster: NAD alcohol dehydrogenase; n=31; Bacter... 42 0.013
UniRef50_Q0RIJ3 Cluster: Putative Zn-dependent alcohol dehydroge... 42 0.013
UniRef50_A1UI23 Cluster: Alcohol dehydrogenase GroES domain prot... 42 0.013
UniRef50_Q6BTK7 Cluster: Similar to sp|Q04894 Saccharomyces cere... 42 0.013
UniRef50_A2QBG7 Cluster: Contig An01c0490, complete genome; n=2;... 42 0.013
UniRef50_UPI000023CF80 Cluster: hypothetical protein FG00231.1; ... 42 0.017
UniRef50_Q28K81 Cluster: Alcohol dehydrogenase zinc-binding; n=3... 42 0.017
UniRef50_Q11C06 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 42 0.017
UniRef50_Q0SBJ8 Cluster: Aryl-alcohol dehydrogenase; n=2; Bacter... 42 0.017
UniRef50_Q0RZT6 Cluster: Probable alcohol dehydrogenase; n=2; Rh... 42 0.017
UniRef50_Q2GU61 Cluster: Putative uncharacterized protein; n=2; ... 42 0.017
UniRef50_Q0U4X3 Cluster: Putative uncharacterized protein; n=1; ... 42 0.017
UniRef50_A3LUA4 Cluster: Secondary alcohol dehydrogenase; n=9; S... 42 0.017
UniRef50_A2QUV3 Cluster: Contig An10c0010, complete genome; n=6;... 42 0.017
UniRef50_Q89RJ2 Cluster: Blr2780 protein; n=10; Proteobacteria|R... 41 0.023
UniRef50_Q1BFA5 Cluster: Alcohol dehydrogenase, zinc-binding pro... 41 0.023
UniRef50_Q0S6W9 Cluster: Zn-binding dehydrogenase; n=4; Actinomy... 41 0.023
UniRef50_A5G4J1 Cluster: Alcohol dehydrogenase GroES domain prot... 41 0.023
UniRef50_A4FD89 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 41 0.023
UniRef50_A1WT70 Cluster: Alcohol dehydrogenase, zinc-binding dom... 41 0.023
UniRef50_A1SI01 Cluster: Alcohol dehydrogenase GroES domain prot... 41 0.023
UniRef50_Q5K773 Cluster: Alcohol dehydrogenase, putative; n=1; F... 41 0.023
UniRef50_O31186 Cluster: Alcohol dehydrogenase; n=105; cellular ... 41 0.023
UniRef50_UPI00005F10EF Cluster: COG1063: Threonine dehydrogenase... 41 0.030
UniRef50_UPI000023E4F0 Cluster: hypothetical protein FG07506.1; ... 41 0.030
UniRef50_Q9KBB7 Cluster: Benzyl alcohol dehydrogenase; n=4; Bact... 41 0.030
UniRef50_A6CDR3 Cluster: Alcohol dehydrogenase, zinc-containing;... 41 0.030
UniRef50_A0LF03 Cluster: Alcohol dehydrogenase GroES domain prot... 41 0.030
UniRef50_A0ADQ4 Cluster: Putative dehydrogenase; n=1; Streptomyc... 41 0.030
UniRef50_Q6ZBH1 Cluster: Putative uncharacterized protein P0623F... 41 0.030
UniRef50_Q965R0 Cluster: Putative uncharacterized protein Y50D4C... 41 0.030
UniRef50_Q4P2L9 Cluster: Putative uncharacterized protein; n=1; ... 41 0.030
UniRef50_Q2MFS3 Cluster: Putative 3-amino-2,3-dideoxy-scyllo-ino... 40 0.040
UniRef50_Q1GL27 Cluster: Alcohol dehydrogenase zinc-binding; n=1... 40 0.040
UniRef50_Q0RGJ0 Cluster: Aryl-alcohol dehydrogenase; n=1; Franki... 40 0.040
UniRef50_A4G6Q5 Cluster: Glutathione-independent formaldehyde de... 40 0.040
UniRef50_A3PJU5 Cluster: Alcohol dehydrogenase GroES domain prot... 40 0.040
UniRef50_A0JVZ3 Cluster: Alcohol dehydrogenase GroES domain prot... 40 0.040
UniRef50_A2X573 Cluster: Putative uncharacterized protein; n=1; ... 40 0.040
UniRef50_Q4WKQ3 Cluster: Formaldehyde dehydrogenase, putative; n... 40 0.040
UniRef50_A4QQS1 Cluster: Putative uncharacterized protein; n=1; ... 40 0.040
UniRef50_A3LVP0 Cluster: Sorbitol dehydrogenase; n=6; Saccharomy... 40 0.040
UniRef50_A1D8I3 Cluster: Alcohol dehydrogenase; n=1; Neosartorya... 40 0.040
UniRef50_Q8ZVD9 Cluster: Alcohol dehydrogenase; n=3; Pyrobaculum... 40 0.040
UniRef50_A3DNG0 Cluster: Alcohol dehydrogenase GroES domain prot... 40 0.040
UniRef50_P37084 Cluster: L-sorbose 1-phosphate reductase; n=21; ... 40 0.040
UniRef50_Q9WYR7 Cluster: Alcohol dehydrogenase, zinc-containing;... 40 0.053
UniRef50_Q81YJ9 Cluster: Quinone oxidoreductase; n=12; Bacteria|... 40 0.053
UniRef50_Q5KW77 Cluster: Alcohol dehydrogenase; n=2; Geobacillus... 40 0.053
UniRef50_Q3WEJ9 Cluster: Zinc-containing alcohol dehydrogenase s... 40 0.053
UniRef50_Q0RJI1 Cluster: Putative zinc-binding dehydrogenase; n=... 40 0.053
UniRef50_Q04H68 Cluster: Threonine dehydrogenase or related Zn-d... 40 0.053
UniRef50_A4AQN2 Cluster: Putative zinc-binding dehydrogenase; n=... 40 0.053
UniRef50_A1UK11 Cluster: Alcohol dehydrogenase, zinc-binding dom... 40 0.053
UniRef50_Q0CK29 Cluster: Putative uncharacterized protein; n=2; ... 40 0.053
UniRef50_A6RNK3 Cluster: NADP-dependent alcohol dehydrogenase; n... 40 0.053
UniRef50_A1DJM6 Cluster: Alcohol dehydrogenase, putative; n=1; N... 40 0.053
UniRef50_A7D2S0 Cluster: Alcohol dehydrogenase GroES domain prot... 40 0.053
UniRef50_P25377 Cluster: NADP-dependent alcohol dehydrogenase 7;... 40 0.053
UniRef50_P00331 Cluster: Alcohol dehydrogenase 2; n=22; Ascomyco... 40 0.053
UniRef50_UPI0000384B5E Cluster: COG1063: Threonine dehydrogenase... 40 0.069
UniRef50_UPI000023DF5F Cluster: hypothetical protein FG11316.1; ... 40 0.069
UniRef50_Q9PCQ1 Cluster: NADP-alcohol dehydrogenase; n=1; Xylell... 40 0.069
UniRef50_Q5LS79 Cluster: Alcohol dehydrogenase, zinc-containing;... 40 0.069
UniRef50_Q46P08 Cluster: Zinc-containing alcohol dehydrogenase s... 40 0.069
UniRef50_O69693 Cluster: POSSIBLE DEHYDROGENASE; n=14; Bacteria|... 40 0.069
UniRef50_Q84H90 Cluster: 6-hydroxyhexanoate dehydrogenase; n=3; ... 40 0.069
UniRef50_Q2AC15 Cluster: Aromatic alcohol dehydrogenase; n=4; Ba... 40 0.069
UniRef50_Q0LPP6 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 40 0.069
UniRef50_O68872 Cluster: Putative uncharacterized protein; n=1; ... 40 0.069
UniRef50_A7BC76 Cluster: Putative uncharacterized protein; n=1; ... 40 0.069
UniRef50_A3P9N6 Cluster: Oxidoreductase, zinc-binding dehydrogen... 40 0.069
UniRef50_A0V2V8 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 40 0.069
UniRef50_A0QRJ4 Cluster: Alcohol dehydrogenase 1; n=2; Corynebac... 40 0.069
UniRef50_Q93ZM6 Cluster: AT5g63620/MBK5_9; n=6; Magnoliophyta|Re... 40 0.069
UniRef50_Q66UT6 Cluster: NAD-and Zn-dependent alcohol dehydrogen... 40 0.069
UniRef50_Q5BH80 Cluster: Putative uncharacterized protein; n=1; ... 40 0.069
UniRef50_Q89ZF3 Cluster: Sorbitol dehydrogenase; n=1; Bacteroide... 39 0.092
UniRef50_Q89G16 Cluster: Blr6532 protein; n=8; Bacteria|Rep: Blr... 39 0.092
UniRef50_Q0SJ18 Cluster: Probable NADPH:quinone reductase; n=1; ... 39 0.092
UniRef50_Q093F8 Cluster: Zinc-containing alcohol dehydrogenase s... 39 0.092
UniRef50_A4FD94 Cluster: Alcohol dehydrogenase GroES-like protei... 39 0.092
UniRef50_A0Y7R8 Cluster: Zn-dependent alcohol dehydrogenase, cla... 39 0.092
UniRef50_A0IU88 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 39 0.092
UniRef50_Q8J2R1 Cluster: Zbd1p; n=2; Gibberella|Rep: Zbd1p - Gib... 39 0.092
UniRef50_Q8J0P3 Cluster: Alcohol dehydrogenase; n=2; Pezizomycot... 39 0.092
UniRef50_Q0CT00 Cluster: Putative uncharacterized protein; n=1; ... 39 0.092
UniRef50_Q0C7U6 Cluster: Predicted protein; n=1; Aspergillus ter... 39 0.092
UniRef50_A2V8B3 Cluster: N-benzyl-3-pyrrolidinol dehydrogenase; ... 39 0.092
UniRef50_A3MWI2 Cluster: Alcohol dehydrogenase GroES domain prot... 39 0.092
UniRef50_P47734 Cluster: S-(hydroxymethyl)glutathione dehydrogen... 39 0.092
UniRef50_P20368 Cluster: Alcohol dehydrogenase 1; n=9; Bacteria|... 39 0.092
UniRef50_UPI000050FE2D Cluster: COG1062: Zn-dependent alcohol de... 39 0.12
UniRef50_Q9A4J4 Cluster: Alcohol dehydrogenase, zinc-containing;... 39 0.12
UniRef50_Q9A212 Cluster: Quinone oxidoreductase; n=2; Bacteria|R... 39 0.12
UniRef50_Q8NTH6 Cluster: Zn-dependent alcohol dehydrogenases; n=... 39 0.12
UniRef50_Q89IR8 Cluster: Bll5566 protein; n=2; Rhizobiales|Rep: ... 39 0.12
UniRef50_Q89C17 Cluster: Bll7981 protein; n=4; Bacteria|Rep: Bll... 39 0.12
UniRef50_Q0S728 Cluster: Alcohol dehydrogenase; n=3; Actinomycet... 39 0.12
UniRef50_Q0RV69 Cluster: Alcohol dehydrogenase; n=21; Actinomyce... 39 0.12
UniRef50_Q08XA0 Cluster: Alcohol dehydrogenase; n=2; Cystobacter... 39 0.12
UniRef50_O52372 Cluster: Aryl-alcohol dehydrogenase homolog; n=3... 39 0.12
UniRef50_A5FC99 Cluster: Alcohol dehydrogenase GroES domain prot... 39 0.12
UniRef50_A2VN88 Cluster: Zinc-type alcohol dehydrogenase (E subu... 39 0.12
UniRef50_A0Z4I6 Cluster: 2-desacetyl-2-hydroxyethyl bacteriochlo... 39 0.12
UniRef50_A0YEK7 Cluster: Quinone oxidoreductase; n=2; unclassifi... 39 0.12
UniRef50_Q17A11 Cluster: Mical; n=6; Eukaryota|Rep: Mical - Aede... 39 0.12
UniRef50_Q6MVR4 Cluster: Related to zinc-containing long-chain a... 39 0.12
UniRef50_Q5AY22 Cluster: Putative uncharacterized protein; n=1; ... 39 0.12
UniRef50_A7EEB7 Cluster: Putative uncharacterized protein; n=1; ... 39 0.12
UniRef50_A4RI44 Cluster: Putative uncharacterized protein; n=1; ... 39 0.12
UniRef50_P48523 Cluster: Cinnamyl-alcohol dehydrogenase; n=110; ... 39 0.12
UniRef50_Q89GJ2 Cluster: Bll6353 protein; n=2; Proteobacteria|Re... 38 0.16
UniRef50_Q392P0 Cluster: Zinc-containing alcohol dehydrogenase s... 38 0.16
UniRef50_Q2JCS2 Cluster: Alcohol dehydrogenase GroES-like; n=5; ... 38 0.16
UniRef50_O67374 Cluster: Alcohol dehydrogenase; n=1; Aquifex aeo... 38 0.16
UniRef50_Q9F8C7 Cluster: Alcohol dehydrogenase; n=6; Streptococc... 38 0.16
UniRef50_Q3WCL0 Cluster: Zinc-containing alcohol dehydrogenase s... 38 0.16
UniRef50_A7CRN0 Cluster: Alcohol dehydrogenase zinc-binding doma... 38 0.16
UniRef50_A1SIJ4 Cluster: Alcohol dehydrogenase, zinc-binding dom... 38 0.16
UniRef50_A0QZ66 Cluster: NAD-dependent alcohol dehydrogenase; n=... 38 0.16
UniRef50_A3ASS3 Cluster: Putative uncharacterized protein; n=2; ... 38 0.16
>UniRef50_O97479 Cluster: CG1982-PA; n=17; Bilateria|Rep: CG1982-PA
- Drosophila melanogaster (Fruit fly)
Length = 360
Score = 196 bits (477), Expect = 5e-49
Identities = 97/165 (58%), Positives = 112/165 (67%)
Frame = +1
Query: 22 MATDNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE 201
MA DNLTA+L+ D+RL Q PIPEI+DDEVLL MD VGICGSDVHY G+ G FVL +
Sbjct: 1 MAKDNLTAVLHGIEDMRLEQRPIPEIADDEVLLAMDSVGICGSDVHYLAHGRIGDFVLTK 60
Query: 202 PMIMGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQ 381
PMI+GHE++GVVAK+G K ++ P +Q P P
Sbjct: 61 PMIIGHESAGVVAKLGKKVTTLKVGDRVAIEPGVPCRKCDHCKQGKYNLCPGMVFCATPP 120
Query: 382 LHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
GNL RYYKHAADFCFKLPDHVTMEEGALLEPL+VG+HACKRAE
Sbjct: 121 YDGNLTRYYKHAADFCFKLPDHVTMEEGALLEPLSVGVHACKRAE 165
Score = 120 bits (290), Expect = 2e-26
Identities = 64/138 (46%), Positives = 84/138 (60%), Gaps = 3/138 (2%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLL 431
+V L VGDRVAIEPGVPCR C+ CK G+Y+LCP M+FCATPP + + + F
Sbjct: 78 KVTTLKVGDRVAIEPGVPCRKCDHCKQGKYNLCPGMVFCATPPYDGNLTRYYKHAADFCF 137
Query: 432 QAS*SRDHG--RRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAH 602
+ DH A P G + V+ G VL+LGAGPIGL+T++ A+A GA
Sbjct: 138 KLP---DHVTMEEGALLEPLSVGVHACKRAEVTLGSKVLILGAGPIGLVTLMAAQAMGAS 194
Query: 603 KVLIIDILQSRLDFAKSL 656
++LI D++Q RLD AK L
Sbjct: 195 EILITDLVQQRLDVAKEL 212
>UniRef50_Q6PGX2 Cluster: Zgc:63674; n=2; Danio rerio|Rep: Zgc:63674
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 594
Score = 169 bits (411), Expect = 5e-41
Identities = 84/164 (51%), Positives = 106/164 (64%)
Frame = +1
Query: 22 MATDNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE 201
M DNL+ +L+ DLRL Q PIPE ++VLL+M VGICGSDVHYWQ G+ G FV+++
Sbjct: 1 MDKDNLSVVLHAKGDLRLEQRPIPEPGPNDVLLQMHSVGICGSDVHYWQNGRIGDFVVKQ 60
Query: 202 PMIMGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQ 381
PMI+GHEASG V K+GS + P V+ +P+ P
Sbjct: 61 PMILGHEASGRVVKVGSAVTHLKPGDRVAVEPGVPREVDEFVKSGHYNLSPSIFFCATPP 120
Query: 382 LHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
GNL RYYKH+A FC+KLPD+VT EEGAL+EPL+VGIHAC+RA
Sbjct: 121 DDGNLCRYYKHSASFCYKLPDNVTYEEGALIEPLSVGIHACRRA 164
Score = 72.1 bits (169), Expect = 1e-11
Identities = 40/111 (36%), Positives = 58/111 (52%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V +L GDRVA+EPGVP EF K+G Y+L P + FCATPP + + + F +
Sbjct: 79 VTHLKPGDRVAVEPGVPREVDEFVKSGHYNLSPSIFFCATPPDDGNLCRYYKHSASFCYK 138
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAK 587
+ + + G + GV+ G V V GAGPIGL+++L +
Sbjct: 139 LPDNVTYEEGALIEPLSVGIHACRRAGVTLGSSVFVCGAGPIGLVSLLAVQ 189
>UniRef50_Q58D31 Cluster: Sorbitol dehydrogenase; n=8;
Eukaryota|Rep: Sorbitol dehydrogenase - Bos taurus
(Bovine)
Length = 356
Score = 169 bits (411), Expect = 5e-41
Identities = 83/161 (51%), Positives = 106/161 (65%)
Frame = +1
Query: 31 DNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 210
+NL+ +++ P DLRL PIPE +EVLL+M VGICGSDVHYWQ G+ G FV+++PM+
Sbjct: 7 ENLSLVVHGPGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMV 66
Query: 211 MGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHG 390
+GHEASG V K+GS R Q P T + +PT P G
Sbjct: 67 LGHEASGTVVKVGSLVRHLQPGDRVAIEPGAPRETDEFCKIGRYNLSPTIFFCATPPDDG 126
Query: 391 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
NL R+YKH A+FC+KLPD+VT EEGAL+EPL+VGIHAC+RA
Sbjct: 127 NLCRFYKHNANFCYKLPDNVTFEEGALIEPLSVGIHACRRA 167
Score = 100 bits (239), Expect = 4e-20
Identities = 55/134 (41%), Positives = 76/134 (56%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V++L GDRVAIEPG P EFCK GRY+L P + FCATPP + + + F +
Sbjct: 82 VRHLQPGDRVAIEPGAPRETDEFCKIGRYNLSPTIFFCATPPDDGNLCRFYKHNANFCYK 141
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
+ + G + GV+ G+ VLV GAGPIGL+++L AKA GA +V++
Sbjct: 142 LPDNVTFEEGALIEPLSVGIHACRRAGVTLGNKVLVCGAGPIGLVSLLAAKAMGAAQVVV 201
Query: 615 IDILQSRLDFAKSL 656
D+ SRL AK +
Sbjct: 202 TDLSASRLSKAKEV 215
>UniRef50_Q00796 Cluster: Sorbitol dehydrogenase; n=35;
Eumetazoa|Rep: Sorbitol dehydrogenase - Homo sapiens
(Human)
Length = 357
Score = 161 bits (391), Expect = 1e-38
Identities = 77/160 (48%), Positives = 104/160 (65%)
Frame = +1
Query: 31 DNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 210
+NL+ +++ P DLRL PIPE +EVLLRM VGICGSDVHYW+ G+ G+F++++PM+
Sbjct: 8 NNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMV 67
Query: 211 MGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHG 390
+GHEASG V K+GS + + P + +P+ P G
Sbjct: 68 LGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDG 127
Query: 391 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKR 510
NL R+YKH A FC+KLPD+VT EEGAL+EPL+VGIHAC+R
Sbjct: 128 NLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRR 167
Score = 106 bits (255), Expect = 4e-22
Identities = 57/134 (42%), Positives = 77/134 (57%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
VK+L GDRVAIEPG P EFCK GRY+L P + FCATPP + + + F +
Sbjct: 83 VKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYK 142
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
+ + G + GGV+ GH VLV GAGPIG++T+L AKA GA +V++
Sbjct: 143 LPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVV 202
Query: 615 IDILQSRLDFAKSL 656
D+ +RL AK +
Sbjct: 203 TDLSATRLSKAKEI 216
>UniRef50_Q02912 Cluster: Sorbitol dehydrogenase; n=1; Bombyx
mori|Rep: Sorbitol dehydrogenase - Bombyx mori (Silk
moth)
Length = 348
Score = 156 bits (378), Expect = 5e-37
Identities = 80/167 (47%), Positives = 109/167 (65%), Gaps = 4/167 (2%)
Frame = +1
Query: 28 TDNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPM 207
T+N A+L+ ND+R+ + P+PEI+DDEVL+++DCVGICGSDV + G CG V+++P+
Sbjct: 2 TENYAAVLHGANDVRIEKIPVPEINDDEVLIKIDCVGICGSDVKLYSTGTCGADVIDKPI 61
Query: 208 IMGHEASGVVAKIGSK---SRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT-*SSAPR 375
++GHE +G V K+G K R+ V P P CR + + P SS
Sbjct: 62 VIGHEGAGTVVKVGDKVSSLRVGDRVAIEPTQP-CRSCELCKRGKYNLCVEPRYCSSMGA 120
Query: 376 PQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
P GNL RYYKH ADFC KLPD++TMEEGA ++PLA+ IHAC RA+
Sbjct: 121 P---GNLCRYYKHVADFCHKLPDNLTMEEGAAVQPLAIVIHACNRAK 164
Score = 90.6 bits (215), Expect = 3e-17
Identities = 48/135 (35%), Positives = 75/135 (55%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLL 431
+V +L VGDRVAIEP PCR CE CK G+Y+LC + +C++ + + + F
Sbjct: 77 KVSSLRVGDRVAIEPTQPCRSCELCKRGKYNLCVEPRYCSSMGAPGNLCRYYKHVADFCH 136
Query: 432 QAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVL 611
+ + +A ++ G +++LGAGPIG+L ++AKA GA K++
Sbjct: 137 KLPDNLTMEEGAAVQPLAIVIHACNRAKITLGSKIVILGAGPIGILCAMSAKAMGASKII 196
Query: 612 IIDILQSRLDFAKSL 656
+ D++QSRLD A L
Sbjct: 197 LTDVVQSRLDAALEL 211
>UniRef50_Q7QAQ4 Cluster: ENSANGP00000011378; n=3; Culicidae|Rep:
ENSANGP00000011378 - Anopheles gambiae str. PEST
Length = 362
Score = 144 bits (349), Expect = 2e-33
Identities = 74/159 (46%), Positives = 93/159 (58%)
Frame = +1
Query: 34 NLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIM 213
NL +++ D R+ + P+P D EVLL MDCVGICGSDVHY G G + L++ M++
Sbjct: 8 NLAGVVHGVEDFRVEEIPMPRPRDHEVLLEMDCVGICGSDVHYVSHGGFGDYKLKDKMVL 67
Query: 214 GHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGN 393
GHE+SGVV +G+ Q+ PA T + P HGN
Sbjct: 68 GHESSGVVVAVGADVTSLQVGDRVAIEPAIGCRTCRHCKAGRYNICPQGVYCVTTG-HGN 126
Query: 394 LVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKR 510
L YY HAAD CFKLP +VTMEEGALLEPLAVG+H C+R
Sbjct: 127 LCNYYTHAADCCFKLPANVTMEEGALLEPLAVGVHCCRR 165
Score = 110 bits (264), Expect = 3e-23
Identities = 61/136 (44%), Positives = 81/136 (59%), Gaps = 1/136 (0%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSR-FL 428
+V +L VGDRVAIEP + CR C CK GRY++CP ++C T A F
Sbjct: 81 DVTSLQVGDRVAIEPAIGCRTCRHCKAGRYNICPQGVYCVTTGHGNLCNYYTHAADCCFK 140
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
L A+ + + G A G H + GGV G VLVLGAGPIGL+T+L AKA GA KV
Sbjct: 141 LPANVTMEEGALLEPLAV-GVHC-CRRGGVGIGSTVLVLGAGPIGLVTLLVAKAMGAAKV 198
Query: 609 LIIDILQSRLDFAKSL 656
+ID+++ +L+ AK+L
Sbjct: 199 CVIDLVERKLELAKTL 214
>UniRef50_UPI0000E46CC1 Cluster: PREDICTED: similar to SORD protein;
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to SORD protein - Strongylocentrotus purpuratus
Length = 292
Score = 132 bits (319), Expect = 7e-30
Identities = 68/166 (40%), Positives = 91/166 (54%)
Frame = +1
Query: 19 DMATDNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLE 198
D+ + A+L D+++ Q + +EVLL + VGICGSD+ YW G CG F L
Sbjct: 2 DLPKETQCAVLCGIKDIKMEQRSVTAPGPNEVLLAVHSVGICGSDLKYWSHGYCGRFKLT 61
Query: 199 EPMIMGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRP 378
PM++GHEASG VA +G + ++ P S R P
Sbjct: 62 APMVIGHEASGTVAALGPGVKHLEVGDRVAIEPGVPCRMCSLCRVGKYNLCRDVQFCATP 121
Query: 379 QLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
+ GNL +YY HAADFCFKLP +V+ EEGAL+EPLAV ++ C RAE
Sbjct: 122 PVDGNLSQYYLHAADFCFKLPSNVSYEEGALVEPLAVALYTCSRAE 167
Score = 77.4 bits (182), Expect = 3e-13
Identities = 47/126 (37%), Positives = 63/126 (50%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
VK+L VGDRVAIEPGVPCR C C+ G+Y+LC D+ FCATPPV Q + F +
Sbjct: 81 VKHLEVGDRVAIEPGVPCRMCSLCRVGKYNLCRDVQFCATPPVDGNLSQYYLHAADFCFK 140
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
+ + + VS G VL+ G+ I + AK GA +L
Sbjct: 141 LPSNVSYEEGALVEPLAVALYTCSRAEVSLGSKVLICGS-DIDDHRLSVAKQNGADYILN 199
Query: 615 IDILQS 632
++ L S
Sbjct: 200 VNGLSS 205
>UniRef50_Q16R00 Cluster: Alcohol dehydrogenase; n=3; Culicidae|Rep:
Alcohol dehydrogenase - Aedes aegypti (Yellowfever
mosquito)
Length = 364
Score = 132 bits (319), Expect = 7e-30
Identities = 68/162 (41%), Positives = 97/162 (59%)
Frame = +1
Query: 31 DNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 210
+NL AL+Y PNDLRL PIPE + +EV++ +D GICG+D+H+ + G G L +P++
Sbjct: 6 ENLCALVYGPNDLRLEPRPIPEPAFNEVVVEVDSCGICGTDIHFLKDGGFGAQRLIKPIV 65
Query: 211 MGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHG 390
+GHE++GVV K+GS+ ++ PA T + + G
Sbjct: 66 LGHESAGVVRKVGSQVTNLKVGDRVAIEPAAGCRTCDLCKVGKYNICLDGKHCTTQKHDG 125
Query: 391 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
N YY AD CFK+PDH+TMEEGALLEPLAV ++A +RA+
Sbjct: 126 NCSNYYAQYADCCFKMPDHMTMEEGALLEPLAVAVYAGRRAQ 167
Score = 77.8 bits (183), Expect = 2e-13
Identities = 50/139 (35%), Positives = 72/139 (51%), Gaps = 4/139 (2%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQ--ARSRF 425
+V NL VGDRVAIEP CR C+ CK G+Y++C D C T A F
Sbjct: 80 QVTNLKVGDRVAIEPAAGCRTCDLCKVGKYNICLDGKHCTTQKHDGNCSNYYAQYADCCF 139
Query: 426 LLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
+ + + G A R + G+ G+ V++ GAGPIGL+ ++ AKA GA +
Sbjct: 140 KMPDHMTMEEGALLEPLAVAVYAGRRAQIGL--GNKVVIFGAGPIGLVCLIAAKAMGATR 197
Query: 606 VLIIDI--LQSRLDFAKSL 656
+I+D+ + RL+ AK L
Sbjct: 198 TVILDLEHAKHRLEVAKKL 216
>UniRef50_Q67XB8 Cluster: Sorbitol dehydrogenase-like protein; n=41;
Magnoliophyta|Rep: Sorbitol dehydrogenase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 364
Score = 131 bits (317), Expect = 1e-29
Identities = 63/172 (36%), Positives = 98/172 (56%)
Frame = +1
Query: 16 SDMATDNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVL 195
S + +N+ A L N L++ +P + +V +RM VGICGSDVHY + C FV+
Sbjct: 12 SKVEEENMAAWLVGINTLKIQPFLLPSVGPHDVRVRMKAVGICGSDVHYLKTMICADFVV 71
Query: 196 EEPMIMGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPR 375
+EPM++GHE +G++ ++G + + + P + R+ P
Sbjct: 72 KEPMVIGHECAGIIEEVGEEVKHLVVGDRVALEPGISCWRCNLCREGRYNLCPEMKFFAT 131
Query: 376 PQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESRRDT 531
P +HG+L H AD CFKLP++V++EEGA+ EPL+VG+HAC+RAE +T
Sbjct: 132 PPVHGSLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPET 183
Score = 105 bits (253), Expect = 7e-22
Identities = 61/137 (44%), Positives = 82/137 (59%), Gaps = 2/137 (1%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRK-PRQILQ-ARSRF 425
EVK+L VGDRVA+EPG+ C C C+ GRY+LCP+M F ATPPV Q++ A F
Sbjct: 91 EVKHLVVGDRVALEPGISCWRCNLCREGRYNLCPEMKFFATPPVHGSLANQVVHPADLCF 150
Query: 426 LLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
L + S + G + R E G VLV+GAGPIGL+TML A+AF +
Sbjct: 151 KLPENVSLEEGAMCEPLSVGVHACRRAEVGPETN--VLVMGAGPIGLVTMLAARAFSVPR 208
Query: 606 VLIIDILQSRLDFAKSL 656
++I+D+ ++RL AK L
Sbjct: 209 IVIVDVDENRLAVAKQL 225
>UniRef50_A1CFY8 Cluster: Xylitol dehydrogenase; n=22;
Ascomycota|Rep: Xylitol dehydrogenase - Aspergillus
clavatus
Length = 380
Score = 127 bits (307), Expect = 2e-28
Identities = 60/161 (37%), Positives = 94/161 (58%), Gaps = 1/161 (0%)
Frame = +1
Query: 34 NLTALLYKPNDLRLVQTPIPEISDD-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 210
NL+ +L + ++ PIPE+ D +V++ + GICGSDVHYW+ G GHFV+++PM+
Sbjct: 32 NLSFVLEGIHQVKFEDRPIPELRDPHDVIVNVKYTGICGSDVHYWEHGAIGHFVVKDPMV 91
Query: 211 MGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHG 390
+GHE+SGVVAK+GS ++ P + + A P G
Sbjct: 92 LGHESSGVVAKVGSAVTSLKVGDRVAMEPGVPCRRCEPCKAGKYNLCEKMAFAATPPYDG 151
Query: 391 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
L +YY DFC+KLP++++++EGAL+EPL V +H ++A
Sbjct: 152 TLAKYYPLPEDFCYKLPENISLQEGALMEPLGVAVHITRQA 192
Score = 107 bits (258), Expect = 2e-22
Identities = 57/133 (42%), Positives = 76/133 (57%), Gaps = 1/133 (0%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V +L VGDRVA+EPGVPCR CE CK G+Y+LC M F ATPP + F +
Sbjct: 107 VTSLKVGDRVAMEPGVPCRRCEPCKAGKYNLCEKMAFAATPPYDGTLAKYYPLPEDFCYK 166
Query: 435 AS*SRDHGRRSATGAPRGGHSRV-QEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVL 611
+ A P G + ++ + G V+V GAGP+GLL A+AFGA K++
Sbjct: 167 LP-ENISLQEGALMEPLGVAVHITRQASIKPGESVVVFGAGPVGLLCCAVARAFGASKII 225
Query: 612 IIDILQSRLDFAK 650
+DI ++RLDFAK
Sbjct: 226 AVDIQKTRLDFAK 238
>UniRef50_Q5KPZ2 Cluster: Sorbitol dehydrogenase, putative; n=1;
Filobasidiella neoformans|Rep: Sorbitol dehydrogenase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 379
Score = 124 bits (300), Expect = 1e-27
Identities = 68/168 (40%), Positives = 102/168 (60%), Gaps = 5/168 (2%)
Frame = +1
Query: 13 ASDMATDNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFV 192
++++ DN + +L+ D+R Q PIPE+ +D+VL+++ GICGSDVHY Q G+ G FV
Sbjct: 2 STELNPDNTSFVLHGVEDVRFDQRPIPEVHNDQVLIKVVKTGICGSDVHYLQHGRIGSFV 61
Query: 193 LEEPMIMGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVG----TASSVRQDDTTYAPT* 360
LEEPM +GHE++GVV K+G R L +E A G + ++ + P
Sbjct: 62 LEEPMCLGHESAGVVVKLGPNVRE-DLGVEVGTRVAMEPGVCCRSCANCKAGLYELCPYM 120
Query: 361 S-SAPRPQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHA 501
S +A P + G L RYY AD LP+ V+ E+GA++EPL+VG+H+
Sbjct: 121 SFAATPPTIFGTLCRYYVLPADLVHPLPESVSFEDGAMMEPLSVGVHS 168
Score = 101 bits (243), Expect = 1e-20
Identities = 60/131 (45%), Positives = 73/131 (55%), Gaps = 3/131 (2%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPV---TRKPRQILQARSRFLLQAS 440
VG RVA+EPGV CR C CK G Y LCP M F ATPP T +L A L S
Sbjct: 91 VGTRVAMEPGVCCRSCANCKAGLYELCPYMSFAATPPTIFGTLCRYYVLPADLVHPLPES 150
Query: 441 *SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIID 620
S + G + G HS GG + V+V GAGP+GLL M AKA GA +++ +D
Sbjct: 151 VSFEDGAMMEPLSV-GVHSVATLGGCKSDQTVIVFGAGPVGLLCMAVAKALGARRIIAVD 209
Query: 621 ILQSRLDFAKS 653
I + RL+FAKS
Sbjct: 210 INKERLEFAKS 220
>UniRef50_Q06004 Cluster: Sorbitol dehydrogenase; n=5;
Bacillales|Rep: Sorbitol dehydrogenase - Bacillus
subtilis
Length = 353
Score = 121 bits (292), Expect = 1e-26
Identities = 55/158 (34%), Positives = 92/158 (58%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A+++ ++++ P+P+I+ DEVL+++ VGICGSD+HY+ G+ G++V+E+P I+GHE
Sbjct: 12 AVMHNTREIKIETLPVPDINHDEVLIKVMAVGICGSDLHYYTNGRIGNYVVEKPFILGHE 71
Query: 223 ASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVR 402
+G +A +GS ++ P G + ++ P P + G V+
Sbjct: 72 CAGEIAAVGSSVDQFKVGDRVAVEPGVTCGRCEACKEGRYNLCPDVQFLATPPVDGAFVQ 131
Query: 403 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
Y K DF F +PD ++ EE AL+EP +VGIHA R +
Sbjct: 132 YIKMRQDFVFLIPDSLSYEEAALIEPFSVGIHAAARTK 169
Score = 101 bits (242), Expect = 2e-20
Identities = 51/134 (38%), Positives = 72/134 (53%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V VGDRVA+EPGV C CE CK GRY+LCPD+ F ATPPV Q ++ R F+
Sbjct: 83 VDQFKVGDRVAVEPGVTCGRCEACKEGRYNLCPDVQFLATPPVDGAFVQYIKMRQDFVFL 142
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
S + + G + G + ++G GP+GL+ + AKAFGA +++
Sbjct: 143 IPDSLSYEEAALIEPFSVGIHAAARTKLQPGSTIAIMGMGPVGLMAVAAAKAFGAGTIIV 202
Query: 615 IDILQSRLDFAKSL 656
D+ RL+ AK +
Sbjct: 203 TDLEPLRLEAAKKM 216
>UniRef50_Q0TT56 Cluster: L-iditol 2-dehydrogenase; n=3;
Clostridiaceae|Rep: L-iditol 2-dehydrogenase -
Clostridium perfringens (strain ATCC 13124 / NCTC 8237 /
Type A)
Length = 348
Score = 119 bits (286), Expect = 7e-26
Identities = 56/150 (37%), Positives = 86/150 (57%)
Frame = +1
Query: 73 LVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 252
L++ IP + ++EVL+++D VGICGSD+HY++ G+ G +++E P ++GHE GVV ++G+
Sbjct: 18 LIERDIPIVKENEVLVKLDYVGICGSDLHYYENGRIGDYIVEPPFVLGHEPGGVVVEVGN 77
Query: 253 KSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADFCF 432
K + + P G + P P + G Y H AD CF
Sbjct: 78 KVKHLNIGDRVALEPGKTCGHCEFCKTGRYNLCPDVIFFATPPVDGVFQEYVAHEADLCF 137
Query: 433 KLPDHVTMEEGALLEPLAVGIHACKRAESR 522
KLP++V+ EGAL+EPLAVG HA + +R
Sbjct: 138 KLPENVSTLEGALIEPLAVGFHAAIQGGAR 167
Score = 114 bits (275), Expect = 2e-24
Identities = 63/137 (45%), Positives = 86/137 (62%), Gaps = 2/137 (1%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQIL--QARSRF 425
+VK+L +GDRVA+EPG C +CEFCKTGRY+LCPD+IF ATPPV ++ + +A F
Sbjct: 78 KVKHLNIGDRVALEPGKTCGHCEFCKTGRYNLCPDVIFFATPPVDGVFQEYVAHEADLCF 137
Query: 426 LLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
L + S G A G H+ +Q GG G +V+GAG IGL++M+ KA G
Sbjct: 138 KLPENVSTLEGALIEPLAV-GFHAAIQ-GGARIGQTAVVMGAGCIGLVSMMALKAMGVSN 195
Query: 606 VLIIDILQSRLDFAKSL 656
V I+DI++ RL+ A L
Sbjct: 196 VYIVDIMEKRLEKALEL 212
>UniRef50_A3TNY9 Cluster: Zinc-binding dehydrogenase; n=5;
Actinomycetales|Rep: Zinc-binding dehydrogenase -
Janibacter sp. HTCC2649
Length = 355
Score = 117 bits (282), Expect = 2e-25
Identities = 61/160 (38%), Positives = 92/160 (57%), Gaps = 3/160 (1%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A+L +P + + P+P + DEVL+ + VG+CGSD HY+ G+ G ++ PM++GHE
Sbjct: 13 AVLAEPGSIVMETRPVPSPAADEVLIEVRSVGVCGSDTHYFDHGRIGEHIVTGPMVLGHE 72
Query: 223 ASGVVAKIGS---KSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGN 393
++GV+ +GS +RI + V P P CR + + P P + G
Sbjct: 73 SAGVIVGVGSGVDPARIGERVAIEPGVP-CR--SCAQCLAGHYNLCPDMVFHATPPIDGT 129
Query: 394 LVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
L Y H + F F LPD V+++EGA+LEPL+VGI AC+RA
Sbjct: 130 LAEYVVHPSSFAFALPDSVSLDEGAMLEPLSVGIWACRRA 169
Score = 100 bits (239), Expect = 4e-20
Identities = 60/132 (45%), Positives = 74/132 (56%), Gaps = 3/132 (2%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPV--TRKPRQILQARSRFLLQAS* 443
+G+RVAIEPGVPCR C C G Y+LCPDM+F ATPP+ T + + F L S
Sbjct: 89 IGERVAIEPGVPCRSCAQCLAGHYNLCPDMVFHATPPIDGTLAEYVVHPSSFAFALPDSV 148
Query: 444 SRDHGRRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIID 620
S D G A P G + GV+ G VLV GAGP+G L A AFGA +V++ D
Sbjct: 149 SLDEG---AMLEPLSVGIWACRRAGVAPGVRVLVTGAGPVGQLAAQVAVAFGASEVVVAD 205
Query: 621 ILQSRLDFAKSL 656
+ RL A SL
Sbjct: 206 VNAHRLSVASSL 217
>UniRef50_Q07786 Cluster: Sorbitol dehydrogenase 2; n=8;
Saccharomycetales|Rep: Sorbitol dehydrogenase 2 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 357
Score = 116 bits (278), Expect = 7e-25
Identities = 61/167 (36%), Positives = 90/167 (53%), Gaps = 1/167 (0%)
Frame = +1
Query: 34 NLTALLYKPNDLRLVQTPIPEISDDE-VLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 210
N +L K D+ + Q PIP I D V L + GICGSD+HY++ G G ++L+ PM+
Sbjct: 6 NPAVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYILKAPMV 65
Query: 211 MGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHG 390
+GHE+SG V ++G ++ P + ++ P + A P + G
Sbjct: 66 LGHESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGSYNLCPHMAFAATPPIDG 125
Query: 391 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESRRDT 531
LV+YY DF KLP+ V+ EEGA +EPL+VG+H+ K A R T
Sbjct: 126 TLVKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGVHSNKLAGVRFGT 172
Score = 96.7 bits (230), Expect = 4e-19
Identities = 53/132 (40%), Positives = 72/132 (54%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V + VGDRVAIEPGVP RY + K G Y+LCP M F ATPP+ + + FL++
Sbjct: 81 VTRVKVGDRVAIEPGVPSRYSDETKEGSYNLCPHMAFAATPPIDGTLVKYYLSPEDFLVK 140
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
+ + G + GV G V+V GAGP+GLLT A+AFGA V+
Sbjct: 141 LPEGVSYEEGACVEPLSVGVHSNKLAGVRFGTKVVVFGAGPVGLLTGAVARAFGATDVIF 200
Query: 615 IDILQSRLDFAK 650
+D+ ++L AK
Sbjct: 201 VDVFDNKLQRAK 212
>UniRef50_Q4WT02 Cluster: Xylitol dehydrogenase; n=8;
Pezizomycotina|Rep: Xylitol dehydrogenase - Aspergillus
fumigatus (Sartorya fumigata)
Length = 383
Score = 113 bits (273), Expect = 3e-24
Identities = 57/168 (33%), Positives = 90/168 (53%), Gaps = 1/168 (0%)
Frame = +1
Query: 79 QTPIPEI-SDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSK 255
+ P P+I S+ +V++R+ G+CGSDVHYWQ G+ G + + P+++GHE+SGV+ GS
Sbjct: 43 ERPTPKIESERDVIVRVVATGLCGSDVHYWQHGRIGRYAVNRPIVLGHESSGVIVACGSN 102
Query: 256 SRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADFCFK 435
++ P T R + A P G L +YK A+ C+K
Sbjct: 103 VDGLKVGDRVALEPGISCNTCKYCRSGHYNLCKSMVFAATPPYDGTLSTFYKVPAECCYK 162
Query: 436 LPDHVTMEEGALLEPLAVGIHACKRAESRRDTWCWYWERDPSVSLPCS 579
LP H+++ +GAL+EPL+V +HAC+ A ++ + P L CS
Sbjct: 163 LPVHISLRDGALVEPLSVAVHACRLAGDMQNKSVVVFGAGPVGLLCCS 210
Score = 87.4 bits (207), Expect = 3e-16
Identities = 50/130 (38%), Positives = 70/130 (53%), Gaps = 2/130 (1%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPV--TRKPRQILQARSRFL 428
V L VGDRVA+EPG+ C C++C++G Y+LC M+F ATPP T + A +
Sbjct: 103 VDGLKVGDRVALEPGISCNTCKYCRSGHYNLCKSMVFAATPPYDGTLSTFYKVPAECCYK 162
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
L S G + R+ G V+V GAGP+GLL A AFGA KV
Sbjct: 163 LPVHISLRDGALVEPLSVAVHACRL--AGDMQNKSVVVFGAGPVGLLCCSVASAFGAAKV 220
Query: 609 LIIDILQSRL 638
+ +D++++RL
Sbjct: 221 VAVDVVKTRL 230
>UniRef50_Q5V6U8 Cluster: Zinc-binding dehydrogenase; n=1;
Haloarcula marismortui|Rep: Zinc-binding dehydrogenase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 343
Score = 113 bits (272), Expect = 4e-24
Identities = 57/157 (36%), Positives = 85/157 (54%)
Frame = +1
Query: 40 TALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 219
TA+L +P + L P P DEVL+ + VGICGSDVHY++ G+ G +V+E+P+++GH
Sbjct: 3 TAVLVEPTEFELEDRPRPSPGPDEVLVAVRDVGICGSDVHYYEHGRIGDYVVEDPLVLGH 62
Query: 220 EASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLV 399
E++G V ++G + P + ++ D + P G
Sbjct: 63 ESAGKVVEVGENVTDHEPGDRVALEPGVPCRRCAHCKRGDYHLCESVRFMATPPHDGAFT 122
Query: 400 RYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKR 510
Y ADF + LP+ V+ EGAL EPL+VGIHAC+R
Sbjct: 123 EYVSWPADFAYTLPESVSTAEGALCEPLSVGIHACRR 159
Score = 95.5 bits (227), Expect = 1e-18
Identities = 48/126 (38%), Positives = 68/126 (53%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SRD 452
GDRVA+EPGVPCR C CK G YHLC + F ATPP + + + F S
Sbjct: 81 GDRVALEPGVPCRRCAHCKRGDYHLCESVRFMATPPHDGAFTEYVSWPADFAYTLPESVS 140
Query: 453 HGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQS 632
+ G + G V G VL+ GAGPIGL+ + A+A GA +++ D+++
Sbjct: 141 TAEGALCEPLSVGIHACRRGSVGTGDTVLITGAGPIGLMVLEAARAAGATDIILTDVVKE 200
Query: 633 RLDFAK 650
+L+FA+
Sbjct: 201 KLEFAE 206
>UniRef50_A5AB83 Cluster: Contig An08c0230, complete genome; n=9;
Ascomycota|Rep: Contig An08c0230, complete genome -
Aspergillus niger
Length = 387
Score = 112 bits (270), Expect = 6e-24
Identities = 61/162 (37%), Positives = 96/162 (59%), Gaps = 4/162 (2%)
Frame = +1
Query: 34 NLTALLYKPNDLRLVQTPIPEISDD-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 210
N + +L+ D+ P+P + D +V + + GICGSDVHYWQ+G+ G F+L+ P++
Sbjct: 35 NRSFVLHAIKDVVFEDRPVPALKDPWDVRVHIAQTGICGSDVHYWQRGRIGDFILKSPIV 94
Query: 211 MGHEASGVVAKIGS---KSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQ 381
+GHE+SG V ++GS ++ + V P P CR G+ + DT +A T P
Sbjct: 95 LGHESSGTVVEVGSAVKNVKVGERVAIEPGVP-CRHGSYNLC--PDTIFAAT------PP 145
Query: 382 LHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACK 507
G L +YY AD+C+ LP+++ +EEGAL+EP+AV + K
Sbjct: 146 HDGTLSKYYTTQADYCYPLPENMDLEEGALVEPVAVAVQITK 187
Score = 91.9 bits (218), Expect = 1e-17
Identities = 59/133 (44%), Positives = 73/133 (54%), Gaps = 2/133 (1%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPV--TRKPRQILQARSRFL 428
VKN+ VG+RVAIEPGVPCR+ G Y+LCPD IF ATPP T QA +
Sbjct: 110 VKNVKVGERVAIEPGVPCRH------GSYNLCPDTIFAATPPHDGTLSKYYTTQADYCYP 163
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
L + + G A ++V G V V+V G GPIGLL +KA+ A KV
Sbjct: 164 LPENMDLEEGALVEPVAVAVQITKV--GKVKPNQTVVVFGCGPIGLLCQAVSKAYSAKKV 221
Query: 609 LIIDILQSRLDFA 647
+ +DI QSR DFA
Sbjct: 222 IGVDISQSRADFA 234
>UniRef50_P36624 Cluster: Putative sorbitol dehydrogenase; n=1;
Schizosaccharomyces pombe|Rep: Putative sorbitol
dehydrogenase - Schizosaccharomyces pombe (Fission
yeast)
Length = 360
Score = 111 bits (268), Expect = 1e-23
Identities = 60/164 (36%), Positives = 84/164 (51%), Gaps = 1/164 (0%)
Frame = +1
Query: 22 MATDNLTALLYKPNDLRLVQTPIPEISDD-EVLLRMDCVGICGSDVHYWQKGQCGHFVLE 198
MA +L K D + P ++DD +V + + GICGSDVHYW++G G F+L+
Sbjct: 1 MAPAEKAFVLRKKMDTAIEDRPGQTLTDDHQVKVAIKATGICGSDVHYWKEGGIGDFILK 60
Query: 199 EPMIMGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRP 378
+PMI+GHE++GVV ++G + P C R P A P
Sbjct: 61 KPMILGHESAGVVVEVGKGVSSLKPGDPVAVEPGCVCRLCDYCRSGRYNLCPHMEFAATP 120
Query: 379 QLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKR 510
G L YY DFC KLP +++EEGAL EP++V +HA R
Sbjct: 121 PYDGTLRTYYITTEDFCTKLPKQISVEEGALFEPMSVAVHAMTR 164
Score = 92.7 bits (220), Expect = 7e-18
Identities = 50/133 (37%), Positives = 70/133 (52%), Gaps = 1/133 (0%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V +L GD VA+EPG CR C++C++GRY+LCP M F ATPP R F +
Sbjct: 80 VSSLKPGDPVAVEPGCVCRLCDYCRSGRYNLCPHMEFAATPPYDGTLRTYYITTEDFCTK 139
Query: 435 AS*SRDHGRRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVL 611
+ A P + G + G VLV+G G +GLL M AKA+GA ++
Sbjct: 140 LP-KQISVEEGALFEPMSVAVHAMTRGNLKCGSRVLVMGCGTVGLLMMAVAKAYGAIDIV 198
Query: 612 IIDILQSRLDFAK 650
+D SR++FA+
Sbjct: 199 AVDASPSRVEFAQ 211
>UniRef50_P22144 Cluster: D-xylulose reductase; n=8;
Saccharomycetales|Rep: D-xylulose reductase - Pichia
stipitis (Yeast)
Length = 363
Score = 108 bits (259), Expect = 1e-22
Identities = 63/168 (37%), Positives = 98/168 (58%), Gaps = 8/168 (4%)
Frame = +1
Query: 28 TDNLTALLYKPNDLRLVQTPIPEISDD-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP 204
T N + +L K +D+ PEIS+ +VL+++ GICGSD+H++ G+ G+FVL +P
Sbjct: 2 TANPSLVLNKIDDISFETYDAPEISEPTDVLVQVKKTGICGSDIHFYAHGRIGNFVLTKP 61
Query: 205 MIMGHEASGVVAKIG---SKSRI*QLVIEWP*SPACRVGTASSVRQD---DTTYAPT*SS 366
M++GHE++G V ++G + ++ V P P+ S + +A T +S
Sbjct: 62 MVLGHESAGTVVQVGKGVTSLKVGDNVAIEPGIPSRFSDEYKSGHYNLCPHMAFAATPNS 121
Query: 367 AP-RPQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACK 507
P G L +Y+K DF KLPDHV++E GAL+EPL+VG+HA K
Sbjct: 122 KEGEPNPPGTLCKYFKSPEDFLVKLPDHVSLELGALVEPLSVGVHASK 169
Score = 84.6 bits (200), Expect = 2e-15
Identities = 55/144 (38%), Positives = 76/144 (52%), Gaps = 10/144 (6%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTR-KPR------QILQA 413
V +L VGD VAIEPG+P R+ + K+G Y+LCP M F ATP +P + ++
Sbjct: 79 VTSLKVGDNVAIEPGIPSRFSDEYKSGHYNLCPHMAFAATPNSKEGEPNPPGTLCKYFKS 138
Query: 414 RSRFLLQAS*SRDHG--RRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTA 584
FL++ DH A P G + G V+ G V V GAGP+GLL A
Sbjct: 139 PEDFLVKLP---DHVSLELGALVEPLSVGVHASKLGSVAFGDYVAVFGAGPVGLLAAAVA 195
Query: 585 KAFGAHKVLIIDILQSRLDFAKSL 656
K FGA V+++DI ++L AK +
Sbjct: 196 KTFGAKGVIVVDIFDNKLKMAKDI 219
>UniRef50_A1DBH5 Cluster: Alcohol dehydrogenase; n=3;
Pezizomycotina|Rep: Alcohol dehydrogenase - Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 386
Score = 107 bits (258), Expect = 2e-22
Identities = 64/170 (37%), Positives = 94/170 (55%), Gaps = 7/170 (4%)
Frame = +1
Query: 34 NLTALLYKPNDLRLVQTPIPEISD-DEVLLRMDCVGICGSDVHYWQKGQCGHFV-LEEPM 207
N + LLY P D R PIP+I D +V++R+ G+CGSDVH+W G V E P+
Sbjct: 11 NPSCLLYGPFDARFEDRPIPQIEDPSDVIIRIAYTGVCGSDVHFWLHGGVKRLVSAEHPI 70
Query: 208 IMGHEASGVVAKIGSKSRI*Q----LVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPR 375
+MGHEASG+V +G Q + IE P P R S R + ++AP
Sbjct: 71 VMGHEASGIVHAVGPSVSTLQPGDHIAIE-PGYPCHRCPCCKSGRYNLCPRMKF-AAAP- 127
Query: 376 PQLHGNLVRYYKHAADFCFKL-PDHVTMEEGALLEPLAVGIHACKRAESR 522
P HG L +Y++ AD+C+K+ P + ++E L+EPLAV +H+ ++ R
Sbjct: 128 PSCHGTLTKYFRLPADYCYKIPPGTLGLDEAVLMEPLAVAVHSVRQVGVR 177
Score = 82.6 bits (195), Expect = 8e-15
Identities = 49/136 (36%), Positives = 71/136 (52%), Gaps = 3/136 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKP-RQILQARSRFLL 431
V L GD +AIEPG PC C CK+GRY+LCP M F A PP + + + +
Sbjct: 87 VSTLQPGDHIAIEPGYPCHRCPCCKSGRYNLCPRMKFAAAPPSCHGTLTKYFRLPADYCY 146
Query: 432 QAS*SRDHGRRSATGAPR--GGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
+ + P HS V++ GV G V+V GAG +GLL A+ FGA
Sbjct: 147 KIPPGTLGLDEAVLMEPLAVAVHS-VRQVGVRPGDRVVVFGAGTVGLLCAAVAREFGAAT 205
Query: 606 VLIIDILQSRLDFAKS 653
+ ++D+ ++L+FA+S
Sbjct: 206 ISMVDLNAAKLEFARS 221
>UniRef50_Q1QUA2 Cluster: Alcohol dehydrogenase, zinc-binding; n=6;
cellular organisms|Rep: Alcohol dehydrogenase,
zinc-binding - Chromohalobacter salexigens (strain DSM
3043 / ATCC BAA-138 / NCIMB13768)
Length = 348
Score = 106 bits (254), Expect = 5e-22
Identities = 59/165 (35%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPE-ISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
+L K +L L +P+ + D+V +R+ VGICGSDVHY+ G+ G FV+ EPM++GHE
Sbjct: 7 VLEKQRELSLRDIDLPDQLGPDDVRIRIHTVGICGSDVHYYTHGRIGPFVVREPMVLGHE 66
Query: 223 ASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVR 402
ASGV+ ++GS ++ P T+ + + P P +HG L
Sbjct: 67 ASGVITEVGSHVSHLKVGERVCMEPGIPDPTSRAAKLGVYNVDPGVRFWATPPVHGCLTP 126
Query: 403 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESRRDTWC 537
H A F F LPD V+ EGA++EP A+G+ A +A + C
Sbjct: 127 EVIHPAAFTFALPDSVSFAEGAMIEPFAIGMQAVVKARMQPGDVC 171
Score = 73.7 bits (173), Expect = 3e-12
Identities = 51/133 (38%), Positives = 68/133 (51%), Gaps = 2/133 (1%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPV--TRKPRQILQARSRFL 428
V +L VG+RV +EPG+P K G Y++ P + F ATPPV P I A F
Sbjct: 78 VSHLKVGERVCMEPGIPDPTSRAAKLGVYNVDPGVRFWATPPVHGCLTPEVIHPAAFTFA 137
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
L S S G A G V + + G V +V GAGPIGL+ L A A GA +V
Sbjct: 138 LPDSVSFAEGAMIEPFAI--GMQAVVKARMQPGDVCVVTGAGPIGLMVALAALAGGASEV 195
Query: 609 LIIDILQSRLDFA 647
L+ D+++ +L A
Sbjct: 196 LVSDLVEEKLAIA 208
>UniRef50_Q1J2J1 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Deinococcus geothermalis DSM 11300|Rep: Alcohol
dehydrogenase GroES-like - Deinococcus geothermalis
(strain DSM 11300)
Length = 359
Score = 104 bits (249), Expect = 2e-21
Identities = 63/171 (36%), Positives = 91/171 (53%), Gaps = 3/171 (1%)
Frame = +1
Query: 19 DMATDNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLE 198
D + + ++L+ DLR +P EV +R+ VG+CGSDVHY+ G+ G FV+E
Sbjct: 5 DSSLSSRISVLHGIRDLRWETREVPAPGPREVRVRVRRVGVCGSDVHYYTHGRIGSFVVE 64
Query: 199 EPMIMGHEASGVVAKIG---SKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSA 369
P+I+GHE GVV +G + R V P P CR + ++ + P +
Sbjct: 65 APLILGHEVMGVVDAVGEGVTHVRPGDRVALEPGVP-CR--RCAFCKRGEYNLCPDMTFM 121
Query: 370 PRPQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESR 522
P +HG L Y DF F LPD ++ + GALLEPLAVGI A ++ + R
Sbjct: 122 ATPPVHGALGEYVLWPDDFAFLLPDRISDDAGALLEPLAVGIWAARKGDVR 172
Score = 101 bits (243), Expect = 1e-20
Identities = 60/136 (44%), Positives = 75/136 (55%), Gaps = 2/136 (1%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQ--ILQARSRFL 428
V ++ GDRVA+EPGVPCR C FCK G Y+LCPDM F ATPPV + + FL
Sbjct: 84 VTHVRPGDRVALEPGVPCRRCAFCKRGEYNLCPDMTFMATPPVHGALGEYVLWPDDFAFL 143
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
L S D G A G ++G V G V V GAGPIG T+ AKA GA +
Sbjct: 144 LPDRISDDAGALLEPLAV--GIWAARKGDVRPGQSVAVFGAGPIGCTTLQAAKAAGATTL 201
Query: 609 LIIDILQSRLDFAKSL 656
+ +D+ RLD A+ +
Sbjct: 202 IAVDLEDFRLDLARKV 217
>UniRef50_Q89F70 Cluster: L-idonate 5-dehydrogenase; n=1;
Bradyrhizobium japonicum|Rep: L-idonate 5-dehydrogenase
- Bradyrhizobium japonicum
Length = 349
Score = 103 bits (248), Expect = 3e-21
Identities = 54/168 (32%), Positives = 89/168 (52%), Gaps = 4/168 (2%)
Frame = +1
Query: 22 MATDNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE 201
M + L A L+ P DLR+++ P+ +++ V +R GICGSD+HY++ + G FV++
Sbjct: 1 MTSTALAATLFGPEDLRMIEHPLDKLASGMVRIRFGAGGICGSDMHYFRHARTGDFVVKS 60
Query: 202 PMIMGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT----*SSA 369
P+++GHE SG V +I + ++ +P+ G + R+ S++
Sbjct: 61 PLVLGHEISGEVVEISGSAANLKVGDRVAVNPSRWCGHCVACREGRPNLCENIYFMGSAS 120
Query: 370 PRPQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
P + G Y+ C K+PDHV+ + AL EPLAV +HA RA
Sbjct: 121 KTPHMQGGFANYFDAIPAQCVKIPDHVSYQAAALAEPLAVCLHAVARA 168
Score = 61.3 bits (142), Expect = 2e-08
Identities = 45/137 (32%), Positives = 63/137 (45%), Gaps = 5/137 (3%)
Frame = +3
Query: 261 NLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQ-ILQARSRFLLQA 437
NL VGDRVA+ P C +C C+ GR +LC ++ F + T + Q
Sbjct: 81 NLKVGDRVAVNPSRWCGHCVACREGRPNLCENIYFMGSASKTPHMQGGFANYFDAIPAQC 140
Query: 438 S*SRDHG--RRSATGAPRGG--HSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
DH + +A P H+ + G + G ++ GAGPIGLLTML A G
Sbjct: 141 VKIPDHVSYQAAALAEPLAVCLHAVARAGNIE-GKRGIIFGAGPIGLLTMLAAHRAGMAD 199
Query: 606 VLIIDILQSRLDFAKSL 656
+ + DI + L FA L
Sbjct: 200 ITVADIAPAPLAFASRL 216
>UniRef50_Q0U204 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 377
Score = 103 bits (248), Expect = 3e-21
Identities = 62/173 (35%), Positives = 96/173 (55%), Gaps = 10/173 (5%)
Frame = +1
Query: 34 NLTALLYKPNDLRLVQTPIPEISD-DEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP-M 207
N + +LY + +L + P+PE+SD + V++R+ VG+CGSDVH++ G G V +
Sbjct: 12 NPSIVLYGAKNAKLEERPVPELSDPNNVIVRIAYVGVCGSDVHFYTHGGIGRSVDPSTGL 71
Query: 208 IMGHEASGVVAKIG---SKSRI*QLVIEWP*SP-----ACRVGTASSVRQDDTTYAPT*S 363
MGHEASG + +G + +I V P +P AC+ GT + R AP
Sbjct: 72 TMGHEASGTITSVGPSVTSFKIGDRVAIEPGTPCRRCAACKSGTYNLCRHMLFAAAPGPP 131
Query: 364 SAPRPQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESR 522
S P G L ++Y+ A D C+ +PD ++++E L+EPLAV +HA K + R
Sbjct: 132 STPGTP--GTLSKFYEMAEDLCYVIPDAISLQEAVLVEPLAVAVHAVKLGDVR 182
Score = 83.0 bits (196), Expect = 6e-15
Identities = 49/138 (35%), Positives = 69/138 (50%), Gaps = 6/138 (4%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATP-----PVTRKPRQILQARS 419
V + +GDRVAIEPG PCR C CK+G Y+LC M+F A P P T +
Sbjct: 88 VTSFKIGDRVAIEPGTPCRRCAACKSGTYNLCRHMLFAAAPGPPSTPGTPGTLSKFYEMA 147
Query: 420 RFLLQAS*SRDHGRRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFG 596
L + + P V+ G V G V+V+G G IGLL A+ FG
Sbjct: 148 EDLCYVIPDAISLQEAVLVEPLAVAVHAVKLGDVRPGETVVVMGCGTIGLLVAAVARLFG 207
Query: 597 AHKVLIIDILQSRLDFAK 650
A +V+++D+ + ++ FAK
Sbjct: 208 ALRVVMVDVREDKVKFAK 225
>UniRef50_Q98D10 Cluster: Putative D-xylulose reductase; n=9;
cellular organisms|Rep: Putative D-xylulose reductase -
Rhizobium loti (Mesorhizobium loti)
Length = 348
Score = 103 bits (246), Expect = 5e-21
Identities = 54/157 (34%), Positives = 85/157 (54%), Gaps = 1/157 (0%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIP-EISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
+L K +L L + +P ++ D+V + + VG+CGSDVHY+ G G +V+ PM++GHE
Sbjct: 5 VLEKKGELSLREIALPLDVGPDDVKIAIHTVGVCGSDVHYYTHGAIGSYVVRAPMVLGHE 64
Query: 223 ASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVR 402
A+G V + G+ + P ++ + + P S P +HG L
Sbjct: 65 AAGTVVETGANVETFKAGDRVCMEPGVPNLSSRATKLGIYNVDPDVSFWATPPVHGVLAP 124
Query: 403 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
Y H A F +KLPD+V+ EGA++EP A+G+ A RA
Sbjct: 125 YAVHPAAFTYKLPDNVSFAEGAMVEPFAIGMQAASRA 161
Score = 66.5 bits (155), Expect = 5e-10
Identities = 47/133 (35%), Positives = 61/133 (45%), Gaps = 2/133 (1%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPV--TRKPRQILQARSRFL 428
V+ GDRV +EPGVP K G Y++ PD+ F ATPPV P + A +
Sbjct: 76 VETFKAGDRVCMEPGVPNLSSRATKLGIYNVDPDVSFWATPPVHGVLAPYAVHPAAFTYK 135
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
L + S G A G + G V +V+G GPIG++ L A A G KV
Sbjct: 136 LPDNVSFAEGAMVEPFAI--GMQAASRARIVPGDVAVVVGCGPIGIMIALAALAGGCSKV 193
Query: 609 LIIDILQSRLDFA 647
LI D +L A
Sbjct: 194 LISDFSAPKLKIA 206
>UniRef50_Q5KPJ4 Cluster: Sorbitol dehydrogenase, putative; n=1;
Filobasidiella neoformans|Rep: Sorbitol dehydrogenase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 416
Score = 102 bits (245), Expect = 7e-21
Identities = 65/164 (39%), Positives = 82/164 (50%), Gaps = 4/164 (2%)
Frame = +3
Query: 171 GSMRTLRAGRTNDHGTRSFRSSGQDRFEVKN--LTVGDRVAIEPGVPCRYCEFCKTGRYH 344
GS +A R+N T + ++ V N L VGD+VA+EPGV CR C CK G+Y
Sbjct: 94 GSNIVQQAARSNVMATARGEAEESNKGTVSNRPLQVGDKVALEPGVTCRMCVDCKGGKYQ 153
Query: 345 LCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SRDHGRRSATGAPR--GGHSRVQEGGV 518
+C MIF A PP T Q A L+ A P H+ GG+
Sbjct: 154 ICEHMIFAAYPPSTGGTLQRYYALPADLVYPLPDNVDLSFGAMMEPLSVATHAVANIGGM 213
Query: 519 SAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAK 650
G VL+ GAGP+GLL M AK GA KV+ +DI + RL FAK
Sbjct: 214 RTGWNVLITGAGPVGLLAMAVAKGLGAGKVIAVDINEERLHFAK 257
Score = 73.3 bits (172), Expect = 5e-12
Identities = 33/76 (43%), Positives = 47/76 (61%)
Frame = +1
Query: 25 ATDNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP 204
A NL +L+ P + +PEI DEVL+ + GICGSDVH++ G+ G L E
Sbjct: 20 AKSNLGFMLHSPLKTSFEEQSVPEIGPDEVLVEIKKTGICGSDVHFYNTGKMGLAALTES 79
Query: 205 MIMGHEASGVVAKIGS 252
M +GHE+SG+V ++GS
Sbjct: 80 MCLGHESSGIVVQLGS 95
>UniRef50_A2QU04 Cluster: Catalytic activity: L-iditol + NAD(+) =
L-sorbose + NADH; n=8; Eurotiomycetidae|Rep: Catalytic
activity: L-iditol + NAD(+) = L-sorbose + NADH -
Aspergillus niger
Length = 405
Score = 100 bits (240), Expect = 3e-20
Identities = 61/168 (36%), Positives = 87/168 (51%), Gaps = 5/168 (2%)
Frame = +1
Query: 25 ATDNLTAL-LYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE 201
+T+ AL L+ DLRL P+ + EV + + G+CGSD+HY+ G+ G FV+ E
Sbjct: 5 STETTQALVLHGAKDLRLESRPLSPPTGSEVQVAIRATGLCGSDLHYYTHGRNGDFVVRE 64
Query: 202 PMIMGHEASGVVAKIG---SKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAP 372
PM +GHE+SG++ IG + + V P + R + SSA
Sbjct: 65 PMCLGHESSGIITAIGPEVTTHAVGDRVALEVGLPCRQCALCQQGRYNICPQMKFRSSAK 124
Query: 373 R-PQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
P L G L+ H A C KLP HV+ GAL+EPLAV +HA +R+
Sbjct: 125 LFPHLDGTLMERTNHPASLCHKLPSHVSYAGGALVEPLAVCLHAIRRS 172
Score = 55.6 bits (128), Expect = 1e-06
Identities = 22/38 (57%), Positives = 27/38 (71%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIF 365
EV VGDRVA+E G+PCR C C+ GRY++CP M F
Sbjct: 82 EVTTHAVGDRVALEVGLPCRQCALCQQGRYNICPQMKF 119
>UniRef50_Q4WT03 Cluster: L-arabinitol 4-dehydrogenase; n=5;
Trichocomaceae|Rep: L-arabinitol 4-dehydrogenase -
Aspergillus fumigatus (Sartorya fumigata)
Length = 359
Score = 100 bits (239), Expect = 4e-20
Identities = 57/158 (36%), Positives = 87/158 (55%), Gaps = 4/158 (2%)
Frame = +1
Query: 61 NDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 240
+DLRLV+ IP++ DE L+ + GICGSDVH+W+ G+ G ++ +GHE++GVV
Sbjct: 19 HDLRLVECEIPKLRPDECLVHVRATGICGSDVHFWKHGRIGPMIVTGDNGLGHESAGVVL 78
Query: 241 KIG-SKSRI---*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYY 408
+IG + +R ++ +E C T S R P P HG L RY+
Sbjct: 79 QIGEAVTRFKPGDRVALEC--GVPCSKPTCSFCRTGKYHACPDVVFFSTPPHHGTLRRYH 136
Query: 409 KHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESR 522
H + K+PD+++ EEG+LLEPL+V + R+ R
Sbjct: 137 AHPEAWLHKIPDNISFEEGSLLEPLSVALAGINRSGLR 174
Score = 90.2 bits (214), Expect = 4e-17
Identities = 49/130 (37%), Positives = 71/130 (54%), Gaps = 2/130 (1%)
Frame = +3
Query: 273 GDRVAIEPGVPCRY--CEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*S 446
GDRVA+E GVPC C FC+TG+YH CPD++F +TPP R+ +L + +
Sbjct: 90 GDRVALECGVPCSKPTCSFCRTGKYHACPDVVFFSTPPHHGTLRRYHAHPEAWLHKIPDN 149
Query: 447 RDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDIL 626
S + + G+ +++ GAGPIGL+T+L A A GA ++I DI
Sbjct: 150 ISFEEGSLLEPLSVALAGINRSGLRLADPLVICGAGPIGLITLLAASAAGAEPIVITDID 209
Query: 627 QSRLDFAKSL 656
++RL AK L
Sbjct: 210 ENRLSKAKEL 219
>UniRef50_Q59545 Cluster: D-xylulose reductase; n=36; Bacteria|Rep:
D-xylulose reductase - Morganella morganii (Proteus
morganii)
Length = 338
Score = 100 bits (239), Expect = 4e-20
Identities = 52/139 (37%), Positives = 78/139 (56%)
Frame = +1
Query: 97 ISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKSRI*QLV 276
+ DD+V +++ VGICGSDVHY+Q G+ G FV++EPM++GHEASGV+ G + ++
Sbjct: 25 LGDDDVEIKIHTVGICGSDVHYYQHGRIGPFVVDEPMVLGHEASGVITAAGKNVKHLKVG 84
Query: 277 IEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADFCFKLPDHVTM 456
P + R P P + G L H A F FKLPD+V+
Sbjct: 85 DRVCMEPGIPDLQSPQSRAGIYNLDPAVRFWATPPIDGCLRESVIHPAAFTFKLPDNVSF 144
Query: 457 EEGALLEPLAVGIHACKRA 513
+GA++EPLA+G+ + +A
Sbjct: 145 AQGAMVEPLAIGMQSATKA 163
Score = 68.9 bits (161), Expect = 1e-10
Identities = 42/132 (31%), Positives = 67/132 (50%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
VK+L VGDRV +EPG+P + G Y+L P + F ATPP+ R+ + + F +
Sbjct: 78 VKHLKVGDRVCMEPGIPDLQSPQSRAGIYNLDPAVRFWATPPIDGCLRESVIHPAAFTFK 137
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
+ + + G + G+ G + LV+GAG IG++T +A A G V+I
Sbjct: 138 LPDNVSFAQGAMVEPLAIGMQSATKAGIKPGDIGLVIGAGTIGIITQ-SALAGGCSDVII 196
Query: 615 IDILQSRLDFAK 650
D+ +L A+
Sbjct: 197 CDVFDEKLKVAE 208
>UniRef50_A3Q0B6 Cluster: Alcohol dehydrogenase GroES domain
protein; n=4; Actinomycetales|Rep: Alcohol dehydrogenase
GroES domain protein - Mycobacterium sp. (strain JLS)
Length = 341
Score = 97.9 bits (233), Expect = 2e-19
Identities = 55/152 (36%), Positives = 81/152 (53%), Gaps = 3/152 (1%)
Frame = +1
Query: 67 LRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 246
LR+ + P+P EVL+ + VG+CGSDVHY++ G+ G FV+EEPMI+GHE SG +A +
Sbjct: 20 LRIEERPVPSPGPHEVLVEVAAVGVCGSDVHYYRHGRIGDFVVEEPMILGHELSGRIAAV 79
Query: 247 G---SKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHA 417
G R+ + V P P R + R + P P + G RY
Sbjct: 80 GEGVDPGRVGERVAVEPQHPCRRCKQCKAGRYN---LCPEMKFYATPPIDGAFCRYVVID 136
Query: 418 ADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
DF +P+ ++ + ALLEPL+V I ++A
Sbjct: 137 DDFAHPVPESMSDDAAALLEPLSVAIATMRKA 168
Score = 93.1 bits (221), Expect = 5e-18
Identities = 46/126 (36%), Positives = 71/126 (56%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SR 449
VG+RVA+EP PCR C+ CK GRY+LCP+M F ATPP+ + + F S
Sbjct: 88 VGERVAVEPQHPCRRCKQCKAGRYNLCPEMKFYATPPIDGAFCRYVVIDDDFAHPVPESM 147
Query: 450 DHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQ 629
+ + +++ GV G +L+ GAGPIG++ A+AFGA ++++ D++
Sbjct: 148 SDDAAALLEPLSVAIATMRKAGVVPGSTILIAGAGPIGVICAQAARAFGAARIVVTDLVP 207
Query: 630 SRLDFA 647
SR + A
Sbjct: 208 SRREMA 213
>UniRef50_A3GIE9 Cluster: Sorbitol dehydrogenase; n=2;
Saccharomycetaceae|Rep: Sorbitol dehydrogenase - Pichia
stipitis (Yeast)
Length = 381
Score = 97.9 bits (233), Expect = 2e-19
Identities = 61/170 (35%), Positives = 84/170 (49%), Gaps = 9/170 (5%)
Frame = +1
Query: 31 DNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 210
+N L L + PIP +EVL+ + C GICGSD+H W+ G G+ L+ +I
Sbjct: 13 ENTCLKLTSDRQLVIDSEPIPICGRNEVLVHIKCTGICGSDIHVWKAGGIGNLQLKSDLI 72
Query: 211 MGHEASGVVAKIGSK----SRI*QLVIEWP*SPA-----CRVGTASSVRQDDTTYAPT*S 363
+GHE SG + IGS+ I V P P C G + D P
Sbjct: 73 LGHECSGEIIHIGSEVTEDFEIGNKVAIEPQLPCGICFLCTNGNMNLCLNVDFMGMPG-M 131
Query: 364 SAPRPQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
P +HG++ RY F +KLPD+VT EEGAL+E L+VG H ++A
Sbjct: 132 PGRLPSIHGSIQRYKTLDPRFVYKLPDNVTYEEGALVEVLSVGYHGIQKA 181
Score = 74.5 bits (175), Expect = 2e-12
Identities = 44/141 (31%), Positives = 77/141 (54%), Gaps = 8/141 (5%)
Frame = +3
Query: 258 KNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVT-RKPR---QILQARS-- 419
++ +G++VAIEP +PC C C G +LC ++ F P + R P I + ++
Sbjct: 90 EDFEIGNKVAIEPQLPCGICFLCTNGNMNLCLNVDFMGMPGMPGRLPSIHGSIQRYKTLD 149
Query: 420 -RFLLQAS*SRDHGRRSATGAPRGGHSRVQE-GGVSAGHVVLVLGAGPIGLLTMLTAKAF 593
RF+ + + + + G+ +Q+ GG+ G + G GPIGL T++ A+A
Sbjct: 150 PRFVYKLPDNVTYEEGALVEVLSVGYHGIQKAGGLELGKPCAIAGCGPIGLATLILAEAA 209
Query: 594 GAHKVLIIDILQSRLDFAKSL 656
GA+ +++ D+ Q +L+FAKSL
Sbjct: 210 GAYPIVVTDVSQEKLNFAKSL 230
>UniRef50_Q5K981 Cluster: L-iditol 2-dehydrogenase, putative; n=6;
Basidiomycota|Rep: L-iditol 2-dehydrogenase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 400
Score = 97.1 bits (231), Expect = 3e-19
Identities = 58/168 (34%), Positives = 90/168 (53%), Gaps = 5/168 (2%)
Frame = +1
Query: 34 NLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCG-HFVLEEPMI 210
NL + ++++++ PIP+ DEV++ + GICGSDVH+W+ GQ G ++ +
Sbjct: 52 NLACAYDEKHNVKMINKPIPKARQDEVVVHIKATGICGSDVHFWKHGQIGPTMIVTDTCG 111
Query: 211 MGHEASGVVAKIGSKSRI*QLVIEWP*SPACRV--GTASSVRQDDTTY--APT*SSAPRP 378
GHE++G V ++G + Q + + C V G AS Y P P
Sbjct: 112 AGHESAGEVVEVG--PGVEQWKVGDRVAIECGVPCGQASCGPCVTGRYNACPQVVFFSTP 169
Query: 379 QLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESR 522
HG L RY+ H A + +LPD+++ EEGAL EP AV + A +RA +R
Sbjct: 170 PYHGTLTRYHAHPASWLHRLPDNLSYEEGALCEPFAVALAALERAGNR 217
Score = 82.6 bits (195), Expect = 8e-15
Identities = 49/136 (36%), Positives = 72/136 (52%), Gaps = 2/136 (1%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRY--CEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFL 428
V+ VGDRVAIE GVPC C C TGRY+ CP ++F +TPP + + +L
Sbjct: 127 VEQWKVGDRVAIECGVPCGQASCGPCVTGRYNACPQVVFFSTPPYHGTLTRYHAHPASWL 186
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
+ + + + + ++ G G VL+ GAGPIGL+T+L + A G +
Sbjct: 187 HRLPDNLSYEEGALCEPFAVALAALERAGNRLGDPVLICGAGPIGLVTLLASHAAGCTPI 246
Query: 609 LIIDILQSRLDFAKSL 656
+I D+ SRL+ AK L
Sbjct: 247 VITDLQASRLEVAKKL 262
>UniRef50_A1DK00 Cluster: Alcohol dehydrogenase; n=7;
Pezizomycotina|Rep: Alcohol dehydrogenase - Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 385
Score = 95.1 bits (226), Expect = 1e-18
Identities = 63/191 (32%), Positives = 99/191 (51%), Gaps = 7/191 (3%)
Frame = +1
Query: 49 LYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 228
L+ P LRL P+ I +V +R+ +CGSDVHY++ + G ++EP+ GHEA+
Sbjct: 13 LHGPQQLRLEARPMTSIGPSDVRIRVRSTTLCGSDVHYFKFHRNGSIEVKEPLCGGHEAA 72
Query: 229 GVVAKIGS---KSRI*QL--VIEWP*SPAC-RVGTASSVRQDDTTYAPT*SS-APRPQLH 387
G V ++G K++ ++ ++ AC S R + SS A P
Sbjct: 73 GEVVEVGPTVLKTQAIRVGDIVAIESGVACLECDKCRSGRYNICAKMRFRSSGASFPHFQ 132
Query: 388 GNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESRRDTWCWYWERDPSVS 567
G L Y H A++C KLPD ++ ++GALLEPL+V IH+ RA + C + +V
Sbjct: 133 GTLQEYVDHPAEWCHKLPDALSYDDGALLEPLSVCIHSVNRAGVDQGARCVVFGAG-AVG 191
Query: 568 LPCSQLKPLEH 600
L C+ + +EH
Sbjct: 192 LLCAAVAKIEH 202
Score = 55.6 bits (128), Expect = 1e-06
Identities = 49/145 (33%), Positives = 68/145 (46%), Gaps = 8/145 (5%)
Frame = +3
Query: 237 GQDRFEVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQ-- 410
G + + + VGD VAIE GV C C+ C++GRY++C M F ++ + LQ
Sbjct: 79 GPTVLKTQAIRVGDIVAIESGVACLECDKCRSGRYNICAKMRFRSSGASFPHFQGTLQEY 138
Query: 411 ----ARSRFLLQAS*SRDHGRRSATGAPRGG--HSRVQEGGVSAGHVVLVLGAGPIGLLT 572
A L + S D G A P HS V GV G +V GAG +GLL
Sbjct: 139 VDHPAEWCHKLPDALSYDDG---ALLEPLSVCIHS-VNRAGVDQGARCVVFGAGAVGLLC 194
Query: 573 MLTAKAFGAHKVLIIDILQSRLDFA 647
AK +V+I D+ + R+ FA
Sbjct: 195 AAVAKIEHKCRVVITDVDEGRVAFA 219
>UniRef50_Q5WJ77 Cluster: Sorbitol dehydrogenase; n=1; Bacillus
clausii KSM-K16|Rep: Sorbitol dehydrogenase - Bacillus
clausii (strain KSM-K16)
Length = 346
Score = 94.3 bits (224), Expect = 2e-18
Identities = 49/148 (33%), Positives = 77/148 (52%)
Frame = +1
Query: 67 LRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 246
+ L + P+ EVL++M VGICGSD+HY++ G+ G V + P ++GHE +GVV K+
Sbjct: 12 IELEERTKPKPGAGEVLIQMKAVGICGSDLHYYEHGRIGERVAKPPFVLGHECAGVVTKV 71
Query: 247 GSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADF 426
G + + P G SS R P P G L+ Y H A F
Sbjct: 72 GPEVADLNVGDHVVIEPGLPCGECSSCRVGHYNLCPKVLFLSSPPNDGVLMEYICHPAKF 131
Query: 427 CFKLPDHVTMEEGALLEPLAVGIHACKR 510
+K+P+ ++ E +L EPL+VG++ ++
Sbjct: 132 TYKMPEGLSFELASLAEPLSVGLYTAQK 159
Score = 90.6 bits (215), Expect = 3e-17
Identities = 44/135 (32%), Positives = 71/135 (52%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLL 431
EV +L VGD V IEPG+PC C C+ G Y+LCP ++F ++PP + + ++F
Sbjct: 74 EVADLNVGDHVVIEPGLPCGECSSCRVGHYNLCPKVLFLSSPPNDGVLMEYICHPAKFTY 133
Query: 432 QAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVL 611
+ S G Q+ + G ++++G GP+GL +L AK +GA ++
Sbjct: 134 KMPEGLSFELASLAEPLSVGLYTAQKTSIQPGSNIVIMGMGPVGLCMILAAKWYGASNIV 193
Query: 612 IIDILQSRLDFAKSL 656
+ DI RL+ AK +
Sbjct: 194 VTDIEPYRLEIAKKI 208
>UniRef50_Q4PHJ5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 382
Score = 94.3 bits (224), Expect = 2e-18
Identities = 49/136 (36%), Positives = 78/136 (57%), Gaps = 2/136 (1%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPC--RYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFL 428
V N+ GDRVAIEPGVPC C+FC+TG+Y+LCP + F + PP ++ + + +L
Sbjct: 93 VDNVVPGDRVAIEPGVPCFKATCDFCRTGKYNLCPTVDFYSVPPKDGTLKRYHEHPAGWL 152
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
+ + + + + +S G VL+ GAGPIG++ +L A A GA +
Sbjct: 153 HKVPDNMSYEEIALLEPLSVTLQATLQAEISLGTPVLITGAGPIGIVQLLCASAAGATPI 212
Query: 609 LIIDILQSRLDFAKSL 656
+I D+++ RLDFA+ +
Sbjct: 213 VITDVVKDRLDFAQKI 228
Score = 85.4 bits (202), Expect = 1e-15
Identities = 53/166 (31%), Positives = 82/166 (49%), Gaps = 4/166 (2%)
Frame = +1
Query: 31 DNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 210
DNL + +L L+++ L+ + G+CGSDVH+W+ G + +E
Sbjct: 18 DNLILMATHKKELELIKSTPAAPGPGMALVHVRATGVCGSDVHFWKHAGLGPWKIESQCA 77
Query: 211 MGHEASGVVAKIG-SKSRI---*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRP 378
+GHE+ G+V +G + ++ IE P P C T R PT P
Sbjct: 78 LGHESGGIVIAVGEGVDNVVPGDRVAIE-PGVP-CFKATCDFCRTGKYNLCPTVDFYSVP 135
Query: 379 QLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
G L RY++H A + K+PD+++ EE ALLEPL+V + A +AE
Sbjct: 136 PKDGTLKRYHEHPAGWLHKVPDNMSYEEIALLEPLSVTLQATLQAE 181
>UniRef50_Q4PCL3 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 387
Score = 92.7 bits (220), Expect = 7e-18
Identities = 51/128 (39%), Positives = 67/128 (52%), Gaps = 1/128 (0%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SR 449
VGDRVA+EPGVPCR C+ C G Y+ C + F ATPP +S F
Sbjct: 98 VGDRVALEPGVPCRSCQVCLNGMYNQCAHLEFAATPPYDGTLCTYYNIQSSFAHHVPDHM 157
Query: 450 DHGRRS-ATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDIL 626
S +S G V A VLV GAGPIGLL KA+ A +V+++D++
Sbjct: 158 SLEEASLMEPLSVAVYSAGMRGQVKAMENVLVFGAGPIGLLNAAVCKAYSAKRVVVVDVV 217
Query: 627 QSRLDFAK 650
+S+L+FAK
Sbjct: 218 ESKLEFAK 225
Score = 83.4 bits (197), Expect = 4e-15
Identities = 44/163 (26%), Positives = 78/163 (47%)
Frame = +1
Query: 13 ASDMATDNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFV 192
A++ A N++ +L + + + PI +V + + G+C SD HY G+ G FV
Sbjct: 12 ATEPAERNVSFVLQEIEKVSFEERPIVAPKPGQVQVNIRQTGLCASDCHYLHHGRIGDFV 71
Query: 193 LEEPMIMGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAP 372
+ +PM++GHE+SG+V +G ++ P + A
Sbjct: 72 VRKPMVLGHESSGIVTAVGEGVTTHKVGDRVALEPGVPCRSCQVCLNGMYNQCAHLEFAA 131
Query: 373 RPQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHA 501
P G L YY + F +PDH+++EE +L+EPL+V +++
Sbjct: 132 TPPYDGTLCTYYNIQSSFAHHVPDHMSLEEASLMEPLSVAVYS 174
>UniRef50_A7II35 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Xanthobacter autotrophicus Py2|Rep:
Alcohol dehydrogenase GroES domain protein -
Xanthobacter sp. (strain Py2)
Length = 345
Score = 91.5 bits (217), Expect = 2e-17
Identities = 58/165 (35%), Positives = 87/165 (52%), Gaps = 8/165 (4%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A+++ DLRL + P PE++ +EVL+ GICGSD+ Y+ KG+ G F L +PM++GHE
Sbjct: 4 AVIHAAKDLRLDECPEPEMAANEVLVSFRAGGICGSDLSYYGKGRVGDFALRQPMVLGHE 63
Query: 223 ASGVVAKIGSKSRI*QL---VIEWP*SPA-----CRVGTASSVRQDDTTYAPT*SSAPRP 378
SG V K+G+ L V P P CR G S++ ++ + S+A P
Sbjct: 64 ISGEVIKLGASVSTLALGDHVAVNPSRPCLECDYCRAG-RSNLCRNMRFFG---SAAIYP 119
Query: 379 QLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
+ G + AD C +P + A+ EPL+V IH +RA
Sbjct: 120 HVQGAFSETFVCRADQCVSVPRDIPFRRVAMAEPLSVAIHGVRRA 164
Score = 71.7 bits (168), Expect = 1e-11
Identities = 48/139 (34%), Positives = 70/139 (50%), Gaps = 6/139 (4%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V L +GD VA+ P PC C++C+ GR +LC +M F + + P F+ +
Sbjct: 75 VSTLALGDHVAVNPSRPCLECDYCRAGRSNLCRNMRFFGSAAIY--PHVQGAFSETFVCR 132
Query: 435 A----S*SRDHG-RRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFG 596
A S RD RR A P V+ G AG VL+ GAGPIG+L + A+ G
Sbjct: 133 ADQCVSVPRDIPFRRVAMAEPLSVAIHGVRRAGELAGKRVLIAGAGPIGMLLAIAARRVG 192
Query: 597 AHKVLIIDILQSRLDFAKS 653
A + I DI+ + L+ A++
Sbjct: 193 ASYIAITDIVDAPLELARA 211
>UniRef50_A1CNK3 Cluster: Xylitol dehydrogenase XdhB, putative;
n=19; Ascomycota|Rep: Xylitol dehydrogenase XdhB,
putative - Aspergillus clavatus
Length = 386
Score = 91.5 bits (217), Expect = 2e-17
Identities = 55/137 (40%), Positives = 79/137 (57%), Gaps = 2/137 (1%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLL 431
+V L GDRVAIEP + C CE C TGRY+ C + F +TPPV R+ + + +
Sbjct: 92 DVTTLKPGDRVAIEPNIICNECEPCLTGRYNGCEKVAFLSTPPVDGLLRRYVNHPAIWCH 151
Query: 432 Q-AS*SRDHGRRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
+ S + G A P + ++ G+ G L+ GAGPIGL+T+L+A+A GA
Sbjct: 152 KIGDMSFEDG---ALLEPLSVSLAAIERSGLRLGDPCLITGAGPIGLITLLSARAAGATP 208
Query: 606 VLIIDILQSRLDFAKSL 656
++I DI + RL+FAKSL
Sbjct: 209 IVITDIDEGRLEFAKSL 225
Score = 71.3 bits (167), Expect = 2e-11
Identities = 45/143 (31%), Positives = 66/143 (46%)
Frame = +1
Query: 109 EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKSRI*QLVIEWP 288
EV + + GICGSDVH+W G G ++E I+GHE++G V + S +
Sbjct: 44 EVTIEVRSTGICGSDVHFWHAGCIGPMIVEGDHILGHESAGQVIAVASDVTTLKPGDRVA 103
Query: 289 *SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADFCFKLPDHVTMEEGA 468
P + P + G L RY H A +C K+ D ++ E+GA
Sbjct: 104 IEPNIICNECEPCLTGRYNGCEKVAFLSTPPVDGLLRRYVNHPAIWCHKIGD-MSFEDGA 162
Query: 469 LLEPLAVGIHACKRAESRRDTWC 537
LLEPL+V + A +R+ R C
Sbjct: 163 LLEPLSVSLAAIERSGLRLGDPC 185
>UniRef50_P77280 Cluster: Uncharacterized zinc-type alcohol
dehydrogenase-like protein ydjJ; n=16; Bacteria|Rep:
Uncharacterized zinc-type alcohol dehydrogenase-like
protein ydjJ - Escherichia coli (strain K12)
Length = 347
Score = 90.2 bits (214), Expect = 4e-17
Identities = 54/163 (33%), Positives = 81/163 (49%), Gaps = 2/163 (1%)
Frame = +1
Query: 34 NLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQ-CGHFVLEEPMI 210
N A+L P ++++ IP +DEVL++++ VGICGSDVH ++ G + +
Sbjct: 3 NSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIG 62
Query: 211 MGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*S-SAPRPQLH 387
+GHE +G V +GS+ R + P G + P A +P
Sbjct: 63 LGHECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYR 122
Query: 388 GNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
G L Y H F +KLPD++ EGAL+EP AVG+HA A+
Sbjct: 123 GALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHAAMLAD 165
Score = 89.8 bits (213), Expect = 5e-17
Identities = 47/135 (34%), Positives = 69/135 (51%), Gaps = 1/135 (0%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKP-RQILQARSRFLL 431
V+ GDRV IEPGVPC +C +C G+Y++CPD+ F AT P R L F
Sbjct: 78 VRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALTHYLCHPESFTY 137
Query: 432 QAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVL 611
+ + D + G V G +++LGAG IGL+T+ K GA ++
Sbjct: 138 KLPDNMDTMEGALVEPAAVGMHAAMLADVKPGKKIIILGAGCIGLMTLQACKCLGATEIA 197
Query: 612 IIDILQSRLDFAKSL 656
++D+L+ RL A+ L
Sbjct: 198 VVDVLEKRLAMAEQL 212
>UniRef50_Q5LQR4 Cluster: L-idonate 5-dehydrogenase; n=13;
Alphaproteobacteria|Rep: L-idonate 5-dehydrogenase -
Silicibacter pomeroyi
Length = 349
Score = 89.8 bits (213), Expect = 5e-17
Identities = 58/155 (37%), Positives = 79/155 (50%), Gaps = 4/155 (2%)
Frame = +1
Query: 49 LYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 228
++ D+R+ P+PE +V++ M GICGSD+HY+ G G + EPMI+GHE +
Sbjct: 8 IHAARDIRVETDPLPEPGPAQVIVAMAAAGICGSDLHYYHDGGFGPIRVREPMILGHEGA 67
Query: 229 GVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT---*SSAPR-PQLHGNL 396
GVVA +G + +P+ GT S + TT+ SA R P G
Sbjct: 68 GVVAALGPGVTGLAVGDRVAVNPSRPCGTCSYCVEGLTTHCLNMRFYGSAMRFPHEQGLF 127
Query: 397 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHA 501
A C KL DHVT+ EGA EPLAV +HA
Sbjct: 128 RDKLLTDAAQCHKLSDHVTISEGACAEPLAVCLHA 162
Score = 59.3 bits (137), Expect = 8e-08
Identities = 47/141 (33%), Positives = 66/141 (46%), Gaps = 7/141 (4%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V L VGDRVA+ P PC C +C G C +M F + R P + R + L
Sbjct: 77 VTGLAVGDRVAVNPSRPCGTCSYCVEGLTTHCLNMRFYGS--AMRFPHEQGLFRDKLLTD 134
Query: 435 AS*SR---DHGRRS--ATGAPRGG--HSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAF 593
A+ DH S A P H+R G V G VLV G+GPIG+L A
Sbjct: 135 AAQCHKLSDHVTISEGACAEPLAVCLHARHMAGEVR-GKRVLVTGSGPIGVLCAAVAAEA 193
Query: 594 GAHKVLIIDILQSRLDFAKSL 656
GA ++++ D+ + L+ A+ +
Sbjct: 194 GAAEIVVTDLQDAPLEVARRM 214
>UniRef50_A7F503 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 420
Score = 89.0 bits (211), Expect = 9e-17
Identities = 54/166 (32%), Positives = 84/166 (50%), Gaps = 4/166 (2%)
Frame = +1
Query: 28 TDNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPM 207
TD ++L+ DL++ + EV + + G+CGSD+HY+ + G ++ EPM
Sbjct: 13 TDVKASVLHGAKDLKVETRTLGVPEPTEVQVAVQATGLCGSDLHYYNHYRNGDIIVREPM 72
Query: 208 IMGHEASGVVAKIGSK---SRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPR- 375
+GHE++GVV +GS+ ++ V P +S R + SSA
Sbjct: 73 TLGHESAGVVTAVGSEVKNLKVGDHVALEVGLPCKNCDLCASGRYNICKEMKFRSSAKAF 132
Query: 376 PQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
P G L H A +C LP +V++E GA+LEPL+V IH +RA
Sbjct: 133 PHFQGTLQERINHPAAYCHLLPSNVSLELGAVLEPLSVAIHGSRRA 178
Score = 79.0 bits (186), Expect = 9e-14
Identities = 50/138 (36%), Positives = 71/138 (51%), Gaps = 6/138 (4%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSR--- 422
EVKNL VGD VA+E G+PC+ C+ C +GRY++C +M F ++ + LQ R
Sbjct: 88 EVKNLKVGDHVALEVGLPCKNCDLCASGRYNICKEMKFRSSAKAFPHFQGTLQERINHPA 147
Query: 423 ---FLLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAF 593
LL ++ S + G + SR + G VL+ GAG +GLL +
Sbjct: 148 AYCHLLPSNVSLELGAVLEPLSVAIHGSR--RAALPKGKTVLIFGAGAVGLLCAAMCRVT 205
Query: 594 GAHKVLIIDILQSRLDFA 647
GA ++I DI RLDFA
Sbjct: 206 GAKNIVIADIQPDRLDFA 223
>UniRef50_A3DI68 Cluster: Alcohol dehydrogenase GroES-like protein;
n=1; Clostridium thermocellum ATCC 27405|Rep: Alcohol
dehydrogenase GroES-like protein - Clostridium
thermocellum (strain ATCC 27405 / DSM 1237)
Length = 347
Score = 87.0 bits (206), Expect = 3e-16
Identities = 44/153 (28%), Positives = 80/153 (52%), Gaps = 1/153 (0%)
Frame = +1
Query: 67 LRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 246
L V+ IP+ E+ +++ VG+CGSD+H++++G+ ++ L+ P+ +GHE G+V+ I
Sbjct: 16 LEWVERDIPQPGRGELQIKLKHVGVCGSDLHFYKEGRLANWELDGPLALGHEPGGIVSAI 75
Query: 247 GSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRP-QLHGNLVRYYKHAAD 423
G ++ + P G R+ P + G Y H+A
Sbjct: 76 GEGVEGFEIGDKVALEPGVPCGECEDCRKGHYNLCKHIKFMAIPHEKDGVFAEYCVHSAS 135
Query: 424 FCFKLPDHVTMEEGALLEPLAVGIHACKRAESR 522
C+KLP++V EG L+EPL+V +HA + + ++
Sbjct: 136 MCYKLPENVDTMEGGLMEPLSVALHATELSNAK 168
Score = 67.7 bits (158), Expect = 2e-10
Identities = 40/132 (30%), Positives = 58/132 (43%), Gaps = 1/132 (0%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V+ +GD+VA+EPGVPC CE C+ G Y+LC + F A P S +
Sbjct: 79 VEGFEIGDKVALEPGVPCGECEDCRKGHYNLCKHIKFMAIPHEKDGVFAEYCVHSASMCY 138
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQE-GGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVL 611
P E G +VLG+G IGL T++ KA G ++
Sbjct: 139 KLPENVDTMEGGLMEPLSVALHATELSNAKIGETAIVLGSGCIGLCTVMALKARGVSEIY 198
Query: 612 IIDILQSRLDFA 647
+ D++ RL+ A
Sbjct: 199 VTDVVDKRLEKA 210
>UniRef50_Q7S9B3 Cluster: Putative uncharacterized protein
NCU07022.1; n=5; Pezizomycotina|Rep: Putative
uncharacterized protein NCU07022.1 - Neurospora crassa
Length = 437
Score = 86.2 bits (204), Expect = 6e-16
Identities = 58/161 (36%), Positives = 78/161 (48%), Gaps = 4/161 (2%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
++L+ P DLRL + I E E+ + + GICGSDV Y++K G P+ +GHE
Sbjct: 26 SVLHGPRDLRLERRTIEEPELGELQVAVKTTGICGSDVSYYKKFANGDLCACMPLSLGHE 85
Query: 223 ASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT---*SSAPR-PQLHG 390
+SGVV IG + L G + R+ SSA P G
Sbjct: 86 SSGVVVAIGPQVSGFSLGDRVALEVGVACGQCTICRKGRYNLCKKMRFRSSAKSVPHYQG 145
Query: 391 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
L H A +C LPDH++ + ALLEPL+VGIHA RA
Sbjct: 146 TLQERINHPAIWCHILPDHISFDAAALLEPLSVGIHAVNRA 186
Score = 71.7 bits (168), Expect = 1e-11
Identities = 48/136 (35%), Positives = 65/136 (47%), Gaps = 4/136 (2%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQAR-SRFL 428
+V ++GDRVA+E GV C C C+ GRY+LC M F ++ + LQ R +
Sbjct: 96 QVSGFSLGDRVALEVGVACGQCTICRKGRYNLCKKMRFRSSAKSVPHYQGTLQERINHPA 155
Query: 429 LQAS*SRDHGRRSATG--APRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGA 599
+ DH A P G V + G LVLGAG +GLLT A+ G
Sbjct: 156 IWCHILPDHISFDAAALLEPLSVGIHAVNRASPAPGSTALVLGAGTVGLLTAAMARQAGC 215
Query: 600 HKVLIIDILQSRLDFA 647
+V I D+ Q R+D A
Sbjct: 216 TQVTITDVDQGRVDHA 231
>UniRef50_Q0UEG3 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 320
Score = 86.2 bits (204), Expect = 6e-16
Identities = 52/136 (38%), Positives = 74/136 (54%), Gaps = 3/136 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPP--VTRKPRQILQARSRFL 428
V +L GDRVA+EPGVPC C C GRY+LC D+ F P T + + AR +
Sbjct: 64 VISLKPGDRVAVEPGVPCETCFLCMDGRYNLCEDVKFSGVYPDAGTIQRYKTHPARWCHI 123
Query: 429 LQAS*SRDHGR-RSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
L ++ S G G ++ G+S G ++ GAGPIGL+ + A+A GAH
Sbjct: 124 LPSNVSYSEGALLEPLSVVMHG---IKSAGLSLGRGAVICGAGPIGLIALAAARASGAHP 180
Query: 606 VLIIDILQSRLDFAKS 653
++I D+ +RL FAK+
Sbjct: 181 LVITDLEPNRLAFAKT 196
Score = 64.9 bits (151), Expect = 2e-09
Identities = 44/128 (34%), Positives = 63/128 (49%), Gaps = 6/128 (4%)
Frame = +1
Query: 148 SDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS---KSRI*QLVIEWP*SPACRVGTA 318
SD+H+W++G+ G V+E I+GHEA+GVV + G + V P P
Sbjct: 28 SDIHFWKRGRIGSLVVEGDCILGHEAAGVVLECGEGVISLKPGDRVAVEPGVPCETCFLC 87
Query: 319 SSVRQ---DDTTYAPT*SSAPRPQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAV 489
R +D ++ A G + RY H A +C LP +V+ EGALLEPL+V
Sbjct: 88 MDGRYNLCEDVKFSGVYPDA------GTIQRYKTHPARWCHILPSNVSYSEGALLEPLSV 141
Query: 490 GIHACKRA 513
+H K A
Sbjct: 142 VMHGIKSA 149
>UniRef50_Q39JN7 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=17; Proteobacteria|Rep: Zinc-containing
alcohol dehydrogenase superfamily - Burkholderia sp.
(strain 383) (Burkholderia cepacia (strain ATCC 17760/
NCIB 9086 / R18194))
Length = 352
Score = 85.0 bits (201), Expect = 1e-15
Identities = 56/166 (33%), Positives = 83/166 (50%), Gaps = 7/166 (4%)
Frame = +1
Query: 37 LTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 216
+ +++ PNDLR+ + EI +V + + GICGSD+HY++ G G L++PM++G
Sbjct: 6 MCVVIHGPNDLRVEEQDAGEIGPGQVRVDVAMGGICGSDLHYFRHGGFGAIRLQQPMVLG 65
Query: 217 HEASGVVAKIG---SKSRI*QLVIEWP*SP--ACRVGTASSVRQ--DDTTYAPT*SSAPR 375
HE +G VA++ + ++ V P P ACR Q D Y S+
Sbjct: 66 HEVAGTVAEVAPDVTSVKVGDRVAVNPSRPCGACRYCLEGLPNQCLDMRFYG---SAMRM 122
Query: 376 PQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
P + G A C K+ DHV + AL EP AVG+HA RA
Sbjct: 123 PHVQGAFRNALVCDAVQCVKVADHVPLSLAALAEPFAVGLHAVSRA 168
Score = 64.5 bits (150), Expect = 2e-09
Identities = 46/141 (32%), Positives = 68/141 (48%), Gaps = 6/141 (4%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFL- 428
+V ++ VGDRVA+ P PC C +C G + C DM F + R P R+ +
Sbjct: 78 DVTSVKVGDRVAVNPSRPCGACRYCLEGLPNQCLDMRFYGS--AMRMPHVQGAFRNALVC 135
Query: 429 --LQAS*SRDHGRRS--ATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAF 593
+Q DH S A P G V G G VLV G GPIG+L + A+
Sbjct: 136 DAVQCVKVADHVPLSLAALAEPFAVGLHAVSRAGPLIGKRVLVSGCGPIGVLAVAAARVH 195
Query: 594 GAHKVLIIDILQSRLDFAKSL 656
GA +++ D++++ L+ A +L
Sbjct: 196 GAAEIVATDVVEAPLEVASAL 216
>UniRef50_Q3ACJ3 Cluster: Sorbitol dehydrogenase; n=1;
Carboxydothermus hydrogenoformans Z-2901|Rep: Sorbitol
dehydrogenase - Carboxydothermus hydrogenoformans
(strain Z-2901 / DSM 6008)
Length = 345
Score = 84.2 bits (199), Expect = 2e-15
Identities = 48/163 (29%), Positives = 79/163 (48%), Gaps = 3/163 (1%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A+L +P + + P+PE+ +VL++++ VGICGSD+H + G G VL++P+++GHE
Sbjct: 4 AVLMEPKKIIFKEVPVPELEKGKVLIKVEAVGICGSDMHLYLDGHIGATVLDKPLVLGHE 63
Query: 223 ASGVVAKIG---SKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGN 393
G V ++G ++ + Q VI P G R P + G
Sbjct: 64 IVGTVIEVGEGVNRELLGQRVIV---DPGENCGQCEHCRTGAYNLCSFSKFKGIPPVDGG 120
Query: 394 LVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESR 522
+ Y A LP+++ LLEP +VG+ A A+ R
Sbjct: 121 MAEYITALATHVIPLPENLDSPTATLLEPFSVGLQAVDVADFR 163
Score = 71.7 bits (168), Expect = 1e-11
Identities = 38/129 (29%), Positives = 62/129 (48%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SR 449
+G RV ++PG C CE C+TG Y+LC F PPV + + A + ++ +
Sbjct: 80 LGQRVIVDPGENCGQCEHCRTGAYNLCSFSKFKGIPPVDGGMAEYITALATHVIPLPENL 139
Query: 450 DHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQ 629
D + G V AG + VLG GP+G+LT + AK G + + ++ +
Sbjct: 140 DSPTATLLEPFSVGLQAVDVADFRAGAKIAVLGGGPVGVLTAIAAKIRGCGDLWLTELYE 199
Query: 630 SRLDFAKSL 656
R++ A+ L
Sbjct: 200 RRIEIARKL 208
>UniRef50_Q2UHR2 Cluster: Sorbitol dehydrogenase; n=8;
Ascomycota|Rep: Sorbitol dehydrogenase - Aspergillus
oryzae
Length = 388
Score = 84.2 bits (199), Expect = 2e-15
Identities = 46/132 (34%), Positives = 69/132 (52%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V +L GDRVA+EPGVPC C C GRY+LC D+ F P ++ ++++ +
Sbjct: 106 VTHLRPGDRVAVEPGVPCGDCFLCLDGRYNLCEDVQFAGVYPYAGTIQRYKTHPAKWVHK 165
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
+ + + + G+ G +V GAGPIGL+ + A+A GAH ++I
Sbjct: 166 LPDNLTYAEGALLEPLSVVMRGMSVAGLQLGRGAVVCGAGPIGLIALAAARASGAHPIVI 225
Query: 615 IDILQSRLDFAK 650
D+ SRL FAK
Sbjct: 226 TDLDASRLAFAK 237
Score = 81.0 bits (191), Expect = 2e-14
Identities = 48/141 (34%), Positives = 66/141 (46%)
Frame = +1
Query: 67 LRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 246
L+ + P+ EVLL++ GICGSD+H+W+ G G + + I+GHEA+GVV K
Sbjct: 43 LKAIDAPVYAPKHGEVLLQIKATGICGSDLHFWKTGCIGELIFKGDCIIGHEAAGVVLKC 102
Query: 247 GSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADF 426
G + P G A G + RY H A +
Sbjct: 103 GEGVTHLRPGDRVAVEPGVPCGDCFLCLDGRYNLCEDVQFAGVYPYAGTIQRYKTHPAKW 162
Query: 427 CFKLPDHVTMEEGALLEPLAV 489
KLPD++T EGALLEPL+V
Sbjct: 163 VHKLPDNLTYAEGALLEPLSV 183
>UniRef50_Q8ELG9 Cluster: Sorbitol dehydrogenase; n=2;
Bacillaceae|Rep: Sorbitol dehydrogenase - Oceanobacillus
iheyensis
Length = 342
Score = 83.8 bits (198), Expect = 3e-15
Identities = 44/143 (30%), Positives = 76/143 (53%)
Frame = +1
Query: 88 IPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKSRI* 267
+PE+ +EV ++++ GICGSD+H + KG H + P+++GHE +G V ++GS
Sbjct: 19 VPELKPNEVQIKVNVAGICGSDIHTY-KGL--HPFRKPPVVIGHEVAGEVVEVGSSVTKF 75
Query: 268 QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADFCFKLPDH 447
++ P G + V + Y+ T + G + Y+ + KLPD
Sbjct: 76 KVGDRVTVEPQIGTGESEGVMTGNVNYSDTRLAPGMGDWLGTMAEYFASPEEQVIKLPDS 135
Query: 448 VTMEEGALLEPLAVGIHACKRAE 516
V+ ++G L+EPLAVG+HA + +
Sbjct: 136 VSYDQGVLVEPLAVGVHAAFKGD 158
Score = 47.2 bits (107), Expect = 3e-04
Identities = 34/134 (25%), Positives = 54/134 (40%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V VGDRV +EP + E TG + + + + +++
Sbjct: 72 VTKFKVGDRVTVEPQIGTGESEGVMTGNVNYSDTRLAPGMGDWLGTMAEYFASPEEQVIK 131
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
S + + G +G V V +LGAGPIGLLT++ KA G +++
Sbjct: 132 LPDSVSYDQGVLVEPLAVGVHAAFKGDVQPTDRVAILGAGPIGLLTLIAVKAKGVKDIVV 191
Query: 615 IDILQSRLDFAKSL 656
D+L L AK +
Sbjct: 192 TDVLDYSLQVAKEM 205
>UniRef50_A1WNS6 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Verminephrobacter eiseniae EF01-2|Rep:
Alcohol dehydrogenase GroES domain protein -
Verminephrobacter eiseniae (strain EF01-2)
Length = 345
Score = 83.8 bits (198), Expect = 3e-15
Identities = 50/161 (31%), Positives = 81/161 (50%), Gaps = 4/161 (2%)
Frame = +1
Query: 49 LYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 228
++ DLR+ P ++ +V + + VGICGSD+HY+Q G+ G FV+ P+ GHEAS
Sbjct: 6 IHGARDLRIADRPAEPLAAHQVRVGVKAVGICGSDLHYYQHGRVGDFVIRAPLTPGHEAS 65
Query: 229 GVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT----*SSAPRPQLHGNL 396
G V ++G++ + Q +P+ G R + S++ P + G +
Sbjct: 66 GQVLELGAQVQGLQPGQRVALNPSRSCGVCRFCRAGAANHCENVHFFGSASKWPHMQGAM 125
Query: 397 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAES 519
A C +PD ++ E A EPLAV +HA ++A S
Sbjct: 126 REQVVLDAAQCIAVPDALSYEVAAFGEPLAVALHAVRQAGS 166
Score = 54.8 bits (126), Expect = 2e-06
Identities = 39/135 (28%), Positives = 63/135 (46%), Gaps = 6/135 (4%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLL 431
+V+ L G RVA+ P C C FC+ G + C ++ F + ++ P R + +L
Sbjct: 74 QVQGLQPGQRVALNPSRSCGVCRFCRAGAANHCENVHFFGS--ASKWPHMQGAMREQVVL 131
Query: 432 QAS*-----SRDHGRRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAF 593
A+ +A G P V++ G G V+V+GAGPIG L ++ A+
Sbjct: 132 DAAQCIAVPDALSYEVAAFGEPLAVALHAVRQAGSLLGKSVMVVGAGPIGALVLMAARLA 191
Query: 594 GAHKVLIIDILQSRL 638
GA ++ DI+ L
Sbjct: 192 GASALIAADIVDQPL 206
>UniRef50_A6X6E2 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Ochrobactrum anthropi ATCC 49188|Rep:
Alcohol dehydrogenase GroES domain protein -
Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 /
NCTC 12168)
Length = 358
Score = 82.6 bits (195), Expect = 8e-15
Identities = 57/164 (34%), Positives = 79/164 (48%), Gaps = 7/164 (4%)
Frame = +1
Query: 49 LYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 228
L+ +DLR+ P+ EVL+ ++ GICGSD+HYW +G G + EP+I+GHEAS
Sbjct: 12 LHAQDDLRIESRPVGTPGPGEVLIAVEAGGICGSDLHYWLEGGIGTIRVREPIILGHEAS 71
Query: 229 GVVAKIGSKSR---I*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*----SSAPRPQLH 387
G + +G QLV P P G S +Q T + S+ P
Sbjct: 72 GRIKALGEGVTGLVPGQLVAMNPSQPC---GICSFCQQGLTRHCSAMRFKGSAMYLPHQQ 128
Query: 388 GNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAES 519
G AAD CF +P+ + A EPLAV +HA R E+
Sbjct: 129 GMFRDRIVIAADQCFPVPNGIDPGAAACSEPLAVCLHAANRGEA 172
Score = 49.2 bits (112), Expect = 9e-05
Identities = 42/141 (29%), Positives = 57/141 (40%), Gaps = 10/141 (7%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V L G VA+ P PC C FC+ G C M F + P Q R R ++
Sbjct: 81 VTGLVPGQLVAMNPSQPCGICSFCQQGLTRHCSAMRFKGSAMYL--PHQQGMFRDRIVIA 138
Query: 435 AS*------SRDHGRRSATGAPRGGHSRVQEG----GVSAGHVVLVLGAGPIGLLTMLTA 584
A D G + + G G G VV+V GAGPIG L + A
Sbjct: 139 ADQCFPVPNGIDPGAAACSEPLAVCLHAANRGEAIAGSLVGKVVMVTGAGPIGALCVAVA 198
Query: 585 KAFGAHKVLIIDILQSRLDFA 647
+ GA ++++ DI + L A
Sbjct: 199 RQRGASEIIVTDIQDATLAVA 219
>UniRef50_A6W685 Cluster: Alcohol dehydrogenase zinc-binding domain
protein; n=1; Kineococcus radiotolerans SRS30216|Rep:
Alcohol dehydrogenase zinc-binding domain protein -
Kineococcus radiotolerans SRS30216
Length = 347
Score = 81.4 bits (192), Expect = 2e-14
Identities = 53/165 (32%), Positives = 79/165 (47%), Gaps = 7/165 (4%)
Frame = +1
Query: 49 LYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 228
++ P DLR+ + PE + EVL+R+ GICGSD+HY G+ G +V+ EP+++GHE
Sbjct: 6 VHAPGDLRVEEVDAPEPAPGEVLVRIVYGGICGSDLHYAADGRNGAYVVTEPLVLGHEVV 65
Query: 229 GVVAKIG----SKSRI*QLVIEWP*SPACRVGTASSV---RQDDTTYAPT*SSAPRPQLH 387
GVV + G + V P +P G A+ + TY S++ P
Sbjct: 66 GVVERAGPDTPAAPPAGTRVAVHPATPCAPAGAAAPTGLHLRPGGTYLG--SASTHPHTQ 123
Query: 388 GNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESR 522
G + +LP + + L EPLAV +HA R E R
Sbjct: 124 GGFTGLLAVGVERLRELPAALPLRRAVLAEPLAVALHAVGRLEGR 168
Score = 37.5 bits (83), Expect = 0.28
Identities = 40/133 (30%), Positives = 55/133 (41%), Gaps = 5/133 (3%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPDMIF---CATPPVTRKPRQILQARSRFLLQAS* 443
G RVA+ P PC HL P + +T P T+ L A L+
Sbjct: 82 GTRVAVHPATPCAPAGAAAPTGLHLRPGGTYLGSASTHPHTQGGFTGLLAVGVERLRELP 141
Query: 444 SRDHGRRSATGAPRGG--HSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLII 617
+ RR+ P H+ + G AG VLV GAGPIG+L + K GA V
Sbjct: 142 AALPLRRAVLAEPLAVALHAVGRLEGRVAGARVLVSGAGPIGVLAVAALKRAGAAHVTAA 201
Query: 618 DILQSRLDFAKSL 656
D+ + L A ++
Sbjct: 202 DLQELPLRVATAV 214
>UniRef50_A6W9X6 Cluster: Alcohol dehydrogenase GroES domain
protein; n=3; Actinomycetales|Rep: Alcohol dehydrogenase
GroES domain protein - Kineococcus radiotolerans
SRS30216
Length = 349
Score = 80.6 bits (190), Expect = 3e-14
Identities = 56/164 (34%), Positives = 80/164 (48%), Gaps = 6/164 (3%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 225
+++ DLR+ + P P+ EVLL ++ GICGSD+ YW+ G G LE P+++GHE
Sbjct: 5 VVHGAGDLRVEERPDPQPGPGEVLLALEWGGICGSDLAYWRHGASGTAQLEHPLVLGHEV 64
Query: 226 SGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQ--DDTTYAPT----*SSAPRPQLH 387
+G VA +G ++ PA VG + T P S+A P
Sbjct: 65 AGTVAALGPDVTGVEVGRAVTVHPATLVGEGDLPARIAGRTNLWPQVRYFGSAAFDPHTD 124
Query: 388 GNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAES 519
G ++ +D LP+ V GAL EPLAV +HA RA S
Sbjct: 125 GGFSQFRTVRSDQLRFLPEGVDTLRGALAEPLAVAMHAVGRAGS 168
Score = 34.3 bits (75), Expect = 2.6
Identities = 21/52 (40%), Positives = 26/52 (50%)
Frame = +3
Query: 501 VQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
V G AG VLV GAGPIG L + A GA V D+ + L A ++
Sbjct: 163 VGRAGSLAGRDVLVNGAGPIGSLVVAAAVHAGAASVTAADVSPAALRVAAAM 214
>UniRef50_A0GHL5 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Burkholderia phytofirmans PsJN|Rep: Alcohol
dehydrogenase GroES-like - Burkholderia phytofirmans
PsJN
Length = 348
Score = 80.2 bits (189), Expect = 4e-14
Identities = 51/168 (30%), Positives = 81/168 (48%), Gaps = 7/168 (4%)
Frame = +1
Query: 37 LTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 216
L A+L++P +R+ + PE EV +R+ GICGSD+ Y+ KG+ G F + EP ++G
Sbjct: 2 LAAVLHEPKLIRIDEVDPPEPGPGEVRVRVRAGGICGSDLSYYFKGKSGDFAVREPFVLG 61
Query: 217 HEASGVVAKIGSKSRI*QLVI---EWP*SPACRVGT----ASSVRQDDTTYAPT*SSAPR 375
HE +G + +G + + +P GT + S++
Sbjct: 62 HEVAGEIDSLGEGVTAERRLAPGQRVAVNPGLACGTCRFCVGGMPNHCLNMRFMGSASTF 121
Query: 376 PQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAES 519
P G +Y AA C +PD V + ++ EPLAV +HA K+A S
Sbjct: 122 PHTQGMFRQYIVVAARQCVPVPDGVDFAQASMAEPLAVALHAVKQAGS 169
Score = 65.7 bits (153), Expect = 9e-10
Identities = 44/146 (30%), Positives = 68/146 (46%), Gaps = 4/146 (2%)
Frame = +3
Query: 231 SSGQDRFEVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIF---CATPPVTRKP-R 398
S G+ + L G RVA+ PG+ C C FC G + C +M F +T P T+ R
Sbjct: 70 SLGEGVTAERRLAPGQRVAVNPGLACGTCRFCVGGMPNHCLNMRFMGSASTFPHTQGMFR 129
Query: 399 QILQARSRFLLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTML 578
Q + +R + D + S V++ G G VL++G GPIG + +
Sbjct: 130 QYIVVAARQCVPVPDGVDFAQASMAEPLAVALHAVKQAGSLVGASVLLVGCGPIGCILLS 189
Query: 579 TAKAFGAHKVLIIDILQSRLDFAKSL 656
A+ GAH+V+ +D+ L A+ L
Sbjct: 190 VARRAGAHRVVALDLSDRALQVARQL 215
>UniRef50_A5I7E3 Cluster: Sorbitol dehydrogenase; n=7;
Clostridium|Rep: Sorbitol dehydrogenase - Clostridium
botulinum A str. ATCC 3502
Length = 349
Score = 79.8 bits (188), Expect = 5e-14
Identities = 41/134 (30%), Positives = 66/134 (49%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V ++ VG+R+A+ P +PC CEFCK G + LC F + + + L+
Sbjct: 75 VDDIKVGERIAVAPLIPCGECEFCKKGNFALCETYEFLGSRNDGGFAEYVRVPKENVLIL 134
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
D+ + + + + G+ G V V+G GPIG + AK FGA KV+
Sbjct: 135 PE-DLDYETAAGIEPASISYQAMSKTGIKVGDTVAVVGCGPIGQFAIQWAKIFGASKVIA 193
Query: 615 IDILQSRLDFAKSL 656
+D+L+ +L+ AK L
Sbjct: 194 VDVLEDKLNLAKEL 207
Score = 51.6 bits (118), Expect = 2e-05
Identities = 40/154 (25%), Positives = 66/154 (42%)
Frame = +1
Query: 49 LYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 228
L+ DLR + IP I +++VL+R+ VGICGSD+ H+ P I GHE S
Sbjct: 10 LHAIKDLRYEEVDIPTIGENDVLVRVKYVGICGSDMPRAMVSGAYHY----PTITGHEFS 65
Query: 229 GVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYY 408
G V +IG+ ++ +P G ++ + T + G Y
Sbjct: 66 GEVVEIGNNVDDIKVGERIAVAPLIPCGECEFCKKGNFALCET-YEFLGSRNDGGFAEYV 124
Query: 409 KHAADFCFKLPDHVTMEEGALLEPLAVGIHACKR 510
+ + LP+ + E A +EP ++ A +
Sbjct: 125 RVPKENVLILPEDLDYETAAGIEPASISYQAMSK 158
>UniRef50_A0JXR0 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=5; Actinobacteria (class)|Rep: Alcohol
dehydrogenase, zinc-binding domain protein -
Arthrobacter sp. (strain FB24)
Length = 355
Score = 79.8 bits (188), Expect = 5e-14
Identities = 50/154 (32%), Positives = 69/154 (44%), Gaps = 4/154 (2%)
Frame = +1
Query: 64 DLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 243
DLR+ P+P DE ++ + GICGSD+HYW G G +L PM++GHE G V
Sbjct: 21 DLRIEDVPVPPPGPDEAVVEVAFGGICGSDLHYWLHGAAGESILRVPMVLGHEIVGTVLH 80
Query: 244 IGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAP----T*SSAPRPQLHGNLVRYYK 411
+ + PA A+ +D +P S+A P G RY
Sbjct: 81 AAADGTGPEAGTPVAVHPATPGPGAARYPEDRPNLSPGCTYLGSAARYPHTDGAFSRYAT 140
Query: 412 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
A LPD +++ AL EP +V HA RA
Sbjct: 141 LPARMLRPLPDGLSLRTAALAEPASVAWHAVARA 174
Score = 39.1 bits (87), Expect = 0.092
Identities = 19/55 (34%), Positives = 33/55 (60%)
Frame = +3
Query: 492 HSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
H+ + G V+ G LV+G+GPIG L + K GA +V+ +D+ L+ A+++
Sbjct: 169 HAVARAGDVT-GKTALVIGSGPIGALAVAVLKRAGARRVVAVDMHPKPLEIAQAV 222
>UniRef50_A6BDE4 Cluster: Putative uncharacterized protein; n=2;
Clostridiales|Rep: Putative uncharacterized protein -
Dorea longicatena DSM 13814
Length = 347
Score = 78.6 bits (185), Expect = 1e-13
Identities = 47/158 (29%), Positives = 75/158 (47%)
Frame = +1
Query: 37 LTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 216
L ++ KP ++ + P+PE+ DD+VL+++ +GICGSD+H + G+ H P+ G
Sbjct: 8 LQQVMTKPGEIIFREVPVPEVKDDQVLVKIMNIGICGSDIHVYH-GK--HPFTSYPVTQG 64
Query: 217 HEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNL 396
HE SG V K+G + + P G R Q G
Sbjct: 65 HEVSGEVVKLGKDVTVFHEGQKVTIEPQVYCGECYPCRHGKYNLCEE-LKVMGFQTTGTA 123
Query: 397 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKR 510
Y+ A +P+ ++ EEGA++EPLAV +H K+
Sbjct: 124 SEYFAVDASKVTPIPEEMSYEEGAMIEPLAVAVHGVKQ 161
Score = 59.7 bits (138), Expect = 6e-08
Identities = 48/135 (35%), Positives = 63/135 (46%), Gaps = 4/135 (2%)
Frame = +3
Query: 258 KNLTV---GDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVTRKPRQILQARSRF 425
K++TV G +V IEP V C C C+ G+Y+LC ++ + T + A
Sbjct: 76 KDVTVFHEGQKVTIEPQVYCGECYPCRHGKYNLCEELKVMGFQTTGTASEYFAVDASKVT 135
Query: 426 LLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
+ S + G A H Q G V G + VLGAGPIG L AK GA K
Sbjct: 136 PIPEEMSYEEGAMIEPLAV-AVHGVKQVGDVK-GMNIAVLGAGPIGNLVAQAAKGMGAAK 193
Query: 606 VLIIDILQSRLDFAK 650
V+I D+ RLD AK
Sbjct: 194 VMITDVSDLRLDKAK 208
>UniRef50_Q5KAN3 Cluster: Xylitol dehydrogenase, putative; n=1;
Filobasidiella neoformans|Rep: Xylitol dehydrogenase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 375
Score = 77.4 bits (182), Expect = 3e-13
Identities = 45/133 (33%), Positives = 72/133 (54%), Gaps = 4/133 (3%)
Frame = +3
Query: 261 NLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT----PPVTRKPRQILQARSRFL 428
NL VGDRVA+E GV C+ C+ C+ GRY+LC +M F ++ P + R+++ + +
Sbjct: 72 NLKVGDRVAMEVGVYCKTCKMCRRGRYNLCANMRFASSAKTYPHLDGTLREVMTWPAELV 131
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
+ + + + + +S G +LV+GAG +GLLT A+A G V
Sbjct: 132 YKLPPNLELPLAALAEPLSVVLHAYRRAHLSPGSRILVIGAGAVGLLTCALARASGCTTV 191
Query: 609 LIIDILQSRLDFA 647
+ +DI Q +LDFA
Sbjct: 192 VAVDIEQGKLDFA 204
Score = 75.8 bits (178), Expect = 9e-13
Identities = 49/150 (32%), Positives = 74/150 (49%), Gaps = 8/150 (5%)
Frame = +1
Query: 88 IPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKSRI* 267
IPE DEV +++ G+CGSD+HY+ G G F + EP+++GHE+ GV+ +GS
Sbjct: 11 IPEPKADEVQIKVAMTGMCGSDLHYYLHGANGTFKIREPLVLGHESCGVITAVGSNVNS- 69
Query: 268 QLVIEWP*SPACRVG----TASSVRQDDTTYAP----T*SSAPRPQLHGNLVRYYKHAAD 423
++ A VG T R+ S+ P L G L A+
Sbjct: 70 GFNLKVGDRVAMEVGVYCKTCKMCRRGRYNLCANMRFASSAKTYPHLDGTLREVMTWPAE 129
Query: 424 FCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
+KLP ++ + AL EPL+V +HA +RA
Sbjct: 130 LVYKLPPNLELPLAALAEPLSVVLHAYRRA 159
>UniRef50_Q188T6 Cluster: Putative sugar-phosphate dehydrogenase;
n=2; Clostridium difficile|Rep: Putative sugar-phosphate
dehydrogenase - Clostridium difficile (strain 630)
Length = 350
Score = 76.2 bits (179), Expect = 7e-13
Identities = 42/136 (30%), Positives = 68/136 (50%), Gaps = 1/136 (0%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLL 431
EV++ +GDRVA+ P +PC C+ CK G Y C ++ + + + + R L+
Sbjct: 71 EVRSFKIGDRVAVCPAMPCFECDECKKGLYSRCNNVAIIGNKELGGCFAEYTKVKERNLI 130
Query: 432 QAS*SRDHGRRSATGAPR-GGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
+ + +A GH + G V+VLG GPIGL ++ AK FG+ K+
Sbjct: 131 KIPDEISYETAAALEPVCIAGHGLFRSEA-KVGDTVVVLGTGPIGLFSIQWAKIFGSTKI 189
Query: 609 LIIDILQSRLDFAKSL 656
+ +D+ +LD AK L
Sbjct: 190 IAVDVFDEKLDLAKEL 205
Score = 62.5 bits (145), Expect = 9e-09
Identities = 44/158 (27%), Positives = 74/158 (46%), Gaps = 1/158 (0%)
Frame = +1
Query: 52 YKPNDLRLVQTPIPEISD-DEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 228
Y D R+ +P+I + D+V++++ GICGSD+ + K H V E I+GHE S
Sbjct: 7 YGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISKYSK-TGPHMVGE---ILGHEFS 62
Query: 229 GVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYY 408
G VA++G + R ++ PA ++ + + +L G Y
Sbjct: 63 GEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSRCNNVAIIGNKELGGCFAEYT 122
Query: 409 KHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESR 522
K K+PD ++ E A LEP+ + H R+E++
Sbjct: 123 KVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK 160
>UniRef50_A6LBP5 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides distasonis ATCC 8503|Rep: Putative
uncharacterized protein - Parabacteroides distasonis
(strain ATCC 8503 / DSM 20701 / NCTC11152)
Length = 347
Score = 75.8 bits (178), Expect = 9e-13
Identities = 51/159 (32%), Positives = 77/159 (48%), Gaps = 3/159 (1%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 225
+L+ DL+ P+P + DEVL+++ GICGSD+ K HF P ++GHE
Sbjct: 5 VLFGIGDLKYTNIPLPRLKSDEVLVKVKAAGICGSDIARVFKTGTYHF----PTVIGHEF 60
Query: 226 SGVVAKIGSKSRI*QL---VIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNL 396
SGVV+ IGS + + L V +P P + + + + S + +G
Sbjct: 61 SGVVSDIGSSTYLSWLGKRVSVFPLKPCFKCNNCKNKEYELCSNYDYLGS----RCNGGF 116
Query: 397 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
Y ++PD V EE A+LEP AV +HA KR+
Sbjct: 117 AEYVAVPVWNLLEIPDCVCYEEAAMLEPAAVALHALKRS 155
Score = 49.6 bits (113), Expect = 6e-05
Identities = 33/128 (25%), Positives = 56/128 (43%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SR 449
+G RV++ P PC C CK Y LC + + + + + LL+
Sbjct: 76 LGKRVSVFPLKPCFKCNNCKNKEYELCSNYDYLGSR-CNGGFAEYVAVPVWNLLEIPDCV 134
Query: 450 DHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQ 629
+ + ++ G G V+V+G G IG++ K GA KV+++ Q
Sbjct: 135 CYEEAAMLEPAAVALHALKRSGFKKGDTVVVIGPGTIGMILSQMVKLLGASKVVLVGRTQ 194
Query: 630 SRLDFAKS 653
++LDFAK+
Sbjct: 195 TKLDFAKT 202
>UniRef50_Q5KJK1 Cluster: Zinc-binding dehydrogenase, putative;
n=16; Dikarya|Rep: Zinc-binding dehydrogenase, putative
- Cryptococcus neoformans (Filobasidiella neoformans)
Length = 349
Score = 75.4 bits (177), Expect = 1e-12
Identities = 46/160 (28%), Positives = 78/160 (48%), Gaps = 1/160 (0%)
Frame = +1
Query: 22 MATDNLTALLY-KPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLE 198
M + ALLY +P + ++ + P+PEI +E+LL++D G+CG+D H + G F+ +
Sbjct: 1 MVAKEMNALLYSEPRNFKITKVPVPEIGPEEILLKVDICGVCGTDQHIHE----GEFIAK 56
Query: 199 EPMIMGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRP 378
P++ GHEA G + +G K + + G R+ + + A
Sbjct: 57 FPLVPGHEAVGRIVSMGDKVKGFDIGDRIAADVGETCGYCHYCRKGTDLFCENFAPAGVA 116
Query: 379 QLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIH 498
+ G Y K+ C+K+ ++T EE LLEP + IH
Sbjct: 117 R-DGGFADYIKYHFAKCYKI-KNLTDEEATLLEPASCAIH 154
Score = 37.1 bits (82), Expect = 0.37
Identities = 13/33 (39%), Positives = 19/33 (57%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLC 350
+VK +GDR+A + G C YC +C+ G C
Sbjct: 75 KVKGFDIGDRIAADVGETCGYCHYCRKGTDLFC 107
>UniRef50_Q9S270 Cluster: Putative zinc-binding alcohol
dehydrogenase; n=3; Actinomycetales|Rep: Putative
zinc-binding alcohol dehydrogenase - Streptomyces
coelicolor
Length = 358
Score = 74.9 bits (176), Expect = 2e-12
Identities = 52/163 (31%), Positives = 73/163 (44%), Gaps = 7/163 (4%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 225
+++ DLR+ P+ E L+ + G+CGSD+HYW+ G G F L EPM++GHE
Sbjct: 16 VIHGAGDLRVTDVPVRPPGPGEALVAVRYGGVCGSDLHYWRHGGVGDFHLREPMLLGHEV 75
Query: 226 SGVVAKIGSKS----RI*QLVIEWP*SPACRVGTASSVRQD---DTTYAPT*SSAPRPQL 384
G V GS V P +P R++ DT Y S+A P +
Sbjct: 76 VGTVVAYGSPDTPGPAAGTSVAVHPATPCGVCPECVDRRRNVCRDTRYLG--SAARFPHV 133
Query: 385 HGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
G A LP + AL EPL+V +HA +RA
Sbjct: 134 QGGFAARIVVPAGQLRPLPAGLDPRRAALAEPLSVALHAVRRA 176
Score = 61.7 bits (143), Expect = 2e-08
Identities = 44/133 (33%), Positives = 62/133 (46%), Gaps = 6/133 (4%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SRD 452
G VA+ P PC C C R ++C D + + R P +R ++ A R
Sbjct: 93 GTSVAVHPATPCGVCPECVDRRRNVCRDTRYLGS--AARFPHVQGGFAARIVVPAGQLRP 150
Query: 453 -----HGRRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
RR+A P V+ G AG VLV GAGPIG L + AKA GA V +
Sbjct: 151 LPAGLDPRRAALAEPLSVALHAVRRAGDPAGRHVLVTGAGPIGCLVVAAAKAAGAAHVTV 210
Query: 615 IDILQSRLDFAKS 653
D+L + L++A++
Sbjct: 211 TDLLPAALEYARA 223
>UniRef50_Q930C9 Cluster: IdnD L-idonate 5-dehydrogenase; n=4;
Alphaproteobacteria|Rep: IdnD L-idonate 5-dehydrogenase
- Rhizobium meliloti (Sinorhizobium meliloti)
Length = 343
Score = 74.5 bits (175), Expect = 2e-12
Identities = 53/160 (33%), Positives = 77/160 (48%), Gaps = 4/160 (2%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 225
+++ DLR+ + + + EV +R+ GICGSD+HY+ G G L+EPMI+GHE
Sbjct: 5 VIHTAKDLRVEECAVEKPGPGEVEIRLAAGGICGSDLHYYNHGGFGTVRLKEPMILGHEV 64
Query: 226 SGVVAKIG---SKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSA-PRPQLHGN 393
SG VA +G S I LV P P + + SA P P + G
Sbjct: 65 SGHVAALGEGVSDLAIGDLVAVSPSRPCGACDYCLKGLPNHCFHMRFYGSAMPFPHIQGA 124
Query: 394 LVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
A C K + ++ E A+ EPL+V +HA +RA
Sbjct: 125 FRERLVAKASQCVK-AEGLSAGEAAMAEPLSVTLHATRRA 163
Score = 60.5 bits (140), Expect = 3e-08
Identities = 40/138 (28%), Positives = 66/138 (47%), Gaps = 4/138 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT----PPVTRKPRQILQARSR 422
V +L +GD VA+ P PC C++C G + C M F + P + R+ L A++
Sbjct: 75 VSDLAIGDLVAVSPSRPCGACDYCLKGLPNHCFHMRFYGSAMPFPHIQGAFRERLVAKAS 134
Query: 423 FLLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAH 602
++A G + + G G VLV G GPIG L++L A+ GA
Sbjct: 135 QCVKAE-GLSAGEAAMAEPLSVTLHATRRAGEMLGKRVLVTGCGPIGTLSILAARRAGAA 193
Query: 603 KVLIIDILQSRLDFAKSL 656
+++ D+ + L FA+++
Sbjct: 194 EIVAADLSERALGFARAV 211
>UniRef50_UPI0000DD8301 Cluster: PREDICTED: similar to Sorbitol
dehydrogenase (L-iditol 2-dehydrogenase); n=1; Homo
sapiens|Rep: PREDICTED: similar to Sorbitol
dehydrogenase (L-iditol 2-dehydrogenase) - Homo sapiens
Length = 323
Score = 73.3 bits (172), Expect = 5e-12
Identities = 30/45 (66%), Positives = 38/45 (84%)
Frame = +1
Query: 376 PQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKR 510
P GNL ++YKH A FC+KLPD+VT EEGAL++PL+VGIHAC+R
Sbjct: 107 PPDDGNLCQFYKHNAAFCYKLPDNVTFEEGALIDPLSVGIHACRR 151
Score = 71.3 bits (167), Expect = 2e-11
Identities = 41/101 (40%), Positives = 50/101 (49%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLL 431
E K L GDRVAIE G P EFCK GRY+L P + FCATPP Q + + F
Sbjct: 66 EQKKLKPGDRVAIESGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCQFYKHNAAFCY 125
Query: 432 QAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAG 554
+ + + G + GGV+ GH VLV GAG
Sbjct: 126 KLPDNVTFEEGALIDPLSVGIHACRRGGVTLGHKVLVCGAG 166
>UniRef50_A4FJI0 Cluster: Putative zinc-binding alcohol
dehydrogenase; n=1; Saccharopolyspora erythraea NRRL
2338|Rep: Putative zinc-binding alcohol dehydrogenase -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 334
Score = 73.3 bits (172), Expect = 5e-12
Identities = 53/155 (34%), Positives = 72/155 (46%), Gaps = 4/155 (2%)
Frame = +1
Query: 49 LYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 228
++ D+RL +PE +D EVLLR+ VGICGSD+HY+ G+ G V+ EP GHE S
Sbjct: 6 IHGAEDMRLEDVAVPEPADGEVLLRVRYVGICGSDLHYYFHGKNGENVVREPFAPGHEFS 65
Query: 229 GVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAP----T*SSAPRPQLHGNL 396
V S + PA R GT D P S+A P G
Sbjct: 66 ATVEADPSGQWAKGTPVTV--HPA-RYGTPVEGIADRPHLWPGGDYLGSAADFPHRQGAA 122
Query: 397 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHA 501
Y +LP+ +++ + AL EPL V +HA
Sbjct: 123 AEYVLVEKPMLRRLPEGLSLRDAALAEPLGVALHA 157
Score = 39.9 bits (89), Expect = 0.053
Identities = 28/68 (41%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
Frame = +3
Query: 459 RRSATGAPRGG--HSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQS 632
R +A P G H+ GG G LVLGAGP+GLL + A G V DI +S
Sbjct: 143 RDAALAEPLGVALHALTIAGG-HLGDRALVLGAGPVGLLIVAALAARGVEHVAAGDIQES 201
Query: 633 RLDFAKSL 656
LD A++L
Sbjct: 202 ALDRARAL 209
>UniRef50_A3PQM0 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Rhodobacter sphaeroides ATCC 17029|Rep:
Alcohol dehydrogenase GroES domain protein - Rhodobacter
sphaeroides (strain ATCC 17029 / ATH 2.4.9)
Length = 345
Score = 73.3 bits (172), Expect = 5e-12
Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 4/155 (2%)
Frame = +1
Query: 64 DLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 243
DL + P + EV L + GICGSD+HY+Q G+ + +L EPMI+GHE SG + +
Sbjct: 11 DLSIEPWAEPALQAGEVRLDLAWGGICGSDLHYFQHGRVANSILREPMILGHEFSGRIRE 70
Query: 244 IGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT----*SSAPRPQLHGNLVRYYK 411
+G + + + +P+ G+ T + S+A P HG
Sbjct: 71 VGPGVQWLKPGMAVAVNPSRPCGSCDQCSAGLTHLCRSMRFMGSAAHFPHTHGGFAERPV 130
Query: 412 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
A C LP+ V + AL EP AV +HA + A+
Sbjct: 131 VLASQCVALPETVDLALAALSEPYAVALHAVELAQ 165
Score = 48.4 bits (110), Expect = 1e-04
Identities = 42/134 (31%), Positives = 60/134 (44%), Gaps = 6/134 (4%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATP---PVTR---KPRQILQAR 416
V+ L G VA+ P PC C+ C G HLC M F + P T R ++ A
Sbjct: 75 VQWLKPGMAVAVNPSRPCGSCDQCSAGLTHLCRSMRFMGSAAHFPHTHGGFAERPVVLAS 134
Query: 417 SRFLLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFG 596
L + S A H+ V+ ++AG VLV GAG IG L + A+ G
Sbjct: 135 QCVALPETVDLALAALSEPYAV-ALHA-VELAQIAAGASVLVTGAGTIGSLVAVAARQAG 192
Query: 597 AHKVLIIDILQSRL 638
A ++++ DI + L
Sbjct: 193 AGRLIVTDIAEPAL 206
>UniRef50_Q5KJG0 Cluster: Xylitol dehydrogenase, putative; n=1;
Filobasidiella neoformans|Rep: Xylitol dehydrogenase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 469
Score = 72.1 bits (169), Expect = 1e-11
Identities = 45/135 (33%), Positives = 64/135 (47%), Gaps = 3/135 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
VK VGDRVAIEPG+PCR C CK G+ ++C +M +C P + +
Sbjct: 120 VKTHKVGDRVAIEPGLPCRRCINCKEGKVNICLNMHYCGAPGSVGSLSRYFALPAD---M 176
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEG---GVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
A DH G + +Q G + V + G GPIGL++ A A+ A K
Sbjct: 177 APHIPDHLSWEEAGCIQPLAVGIQVGKRVDLRPHKTVAIFGCGPIGLISAAVAHAYSARK 236
Query: 606 VLIIDILQSRLDFAK 650
++ D R++FAK
Sbjct: 237 IIAFDNNPQRVEFAK 251
Score = 70.9 bits (166), Expect = 2e-11
Identities = 40/128 (31%), Positives = 61/128 (47%)
Frame = +1
Query: 139 ICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTA 318
ICGSD+H + G G + EP++MGHE+SG V +G + ++ P
Sbjct: 81 ICGSDLHNYLAGGVGGRPVTEPIVMGHESSGEVIAVGDLVKTHKVGDRVAIEPGLPCRRC 140
Query: 319 SSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIH 498
+ ++ P G+L RY+ AD +PDH++ EE ++PLAVGI
Sbjct: 141 INCKEGKVNICLNMHYCGAPGSVGSLSRYFALPADMAPHIPDHLSWEEAGCIQPLAVGIQ 200
Query: 499 ACKRAESR 522
KR + R
Sbjct: 201 VGKRVDLR 208
>UniRef50_Q8EL78 Cluster: Alcohol dehydrogenase; n=1; Oceanobacillus
iheyensis|Rep: Alcohol dehydrogenase - Oceanobacillus
iheyensis
Length = 351
Score = 71.3 bits (167), Expect = 2e-11
Identities = 54/180 (30%), Positives = 75/180 (41%)
Frame = +3
Query: 117 AAHGLRGYLRVRCPLLAEGSMRTLRAGRTNDHGTRSFRSSGQDRFEVKNLTVGDRVAIEP 296
A HG G ++V P G M L G + G+ V L+VGDRVAIEP
Sbjct: 43 AYHGAEGVVQVGEPHPVTGEMAPLTLGH---EFSGVIHEIGEG---VSGLSVGDRVAIEP 96
Query: 297 GVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SRDHGRRSATG 476
+ C CE C G Y+LC F + + + + +A
Sbjct: 97 AIKCGKCENCVRGNYNLCEHNGFVGLQSDGAFAEYAI-VDPHMVHKLPDNISFEEATAIE 155
Query: 477 APRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
++ + AG V V G GPIGL +L AKA GA ++ ID+ RL+ A+ L
Sbjct: 156 PTAVSFHALKLSNMKAGDTVAVFGVGPIGLTAILCAKAAGASRIYAIDVSNERLEMAQKL 215
Score = 57.2 bits (132), Expect = 3e-07
Identities = 47/163 (28%), Positives = 71/163 (43%), Gaps = 8/163 (4%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKG----QCG--HFVLEE- 201
A+ Y +D+R+ P I +V +++ GICGSD+H + Q G H V E
Sbjct: 4 AVWYGKHDIRVENKEEPIIKPGKVKIKVAWTGICGSDLHAYHGAEGVVQVGEPHPVTGEM 63
Query: 202 -PMIMGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRP 378
P+ +GHE SGV+ +IG + PA + G + + + +
Sbjct: 64 APLTLGHEFSGVIHEIGEGVSGLSVGDRVAIEPAIKCGKCENCVRGNYNLCEH-NGFVGL 122
Query: 379 QLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACK 507
Q G Y KLPD+++ EE +EP AV HA K
Sbjct: 123 QSDGAFAEYAIVDPHMVHKLPDNISFEEATAIEPTAVSFHALK 165
>UniRef50_Q7SHA1 Cluster: Putative uncharacterized protein
NCU01905.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU01905.1 - Neurospora crassa
Length = 412
Score = 70.1 bits (164), Expect = 4e-11
Identities = 30/79 (37%), Positives = 49/79 (62%)
Frame = +1
Query: 22 MATDNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE 201
MAT ++L+ DL + P+P +S +VL+ + G+CGSD+HY+ + G + E
Sbjct: 1 MATTIKASVLHGARDLSVESRPLPTLSPTDVLISIKSTGLCGSDLHYYTHFRNGDIQVHE 60
Query: 202 PMIMGHEASGVVAKIGSKS 258
P+ +GHE+SG++ IGS S
Sbjct: 61 PLTLGHESSGIITAIGSPS 79
Score = 45.2 bits (102), Expect = 0.001
Identities = 22/46 (47%), Positives = 25/46 (54%)
Frame = +1
Query: 376 PQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
P G L H A +C KLP+ V GAL EPLAV +HA RA
Sbjct: 158 PHAQGTLQEVVAHPAKWCHKLPESVDYTLGALAEPLAVAMHAAGRA 203
Score = 35.9 bits (79), Expect = 0.86
Identities = 14/21 (66%), Positives = 15/21 (71%)
Frame = +3
Query: 264 LTVGDRVAIEPGVPCRYCEFC 326
L VGDRVA+E G PC CE C
Sbjct: 86 LNVGDRVALEVGQPCEACELC 106
>UniRef50_A0V2V9 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Clostridium cellulolyticum H10|Rep: Alcohol
dehydrogenase GroES-like - Clostridium cellulolyticum
H10
Length = 356
Score = 69.7 bits (163), Expect = 6e-11
Identities = 38/135 (28%), Positives = 64/135 (47%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLL 431
+VKN VGDRV P V C+ C++CK G+ C + + + + + + ++
Sbjct: 75 KVKNAKVGDRVTAMPLVNCKECDYCKIGQAITCDNYDYYGSR-IDGAMAEYIVVSEENII 133
Query: 432 QAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVL 611
+ + + T V++ + AG +V G G IG +T+ K G HKV+
Sbjct: 134 HIPDNVSYYEAAMTDPVSVALHAVRKAEIEAGQTAVVFGLGAIGFITIQWLKHMGCHKVI 193
Query: 612 IIDILQSRLDFAKSL 656
+DI+ +LD AK L
Sbjct: 194 AVDIIDEKLDMAKKL 208
Score = 64.5 bits (150), Expect = 2e-09
Identities = 46/166 (27%), Positives = 86/166 (51%), Gaps = 10/166 (6%)
Frame = +1
Query: 49 LYKPNDLRLVQTPIPEIS-DDEVLLRMDCVGICGSDV-HYWQKGQCGHFVLEEPMIMGHE 222
L+ P D+R IP IS D++V+++++ G+CGSD+ KG P+++GHE
Sbjct: 10 LFAPGDVRCELIDIPVISADNQVIIKVEACGVCGSDIPRVMSKG-----AYRYPIVIGHE 64
Query: 223 ASGVVAKIGSK---SRI*QLVIEWP-----*SPACRVGTASSVRQDDTTYAPT*SSAPRP 378
SG V ++G+K +++ V P C++G A + D+ Y +
Sbjct: 65 FSGEVVEVGTKVKNAKVGDRVTAMPLVNCKECDYCKIGQA--ITCDNYDYYGS------- 115
Query: 379 QLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
++ G + Y + + +PD+V+ E A+ +P++V +HA ++AE
Sbjct: 116 RIDGAMAEYIVVSEENIIHIPDNVSYYEAAMTDPVSVALHAVRKAE 161
>UniRef50_A5JSX4 Cluster: Zinc-containing alcohol dehydrogenase;
n=1; Bacillus megaterium|Rep: Zinc-containing alcohol
dehydrogenase - Bacillus megaterium
Length = 343
Score = 68.9 bits (161), Expect = 1e-10
Identities = 45/129 (34%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
Frame = +3
Query: 267 TVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRF-LLQAS* 443
++GDRVA+EP + C CE C G++H+C + + + +R LL
Sbjct: 75 SLGDRVAVEPTLSCGTCEACVKGQFHVCKQLKLIGIDQDGGFAQHVAVPVNRLHLLPEKL 134
Query: 444 SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDI 623
S +H + A H+ V+ + G ++LGAGPIGLL + AK GA KV+I DI
Sbjct: 135 SSEHAALAEPVAV-AVHT-VRRSRLKVGDQAVILGAGPIGLLIGMIAKRAGAKKVMISDI 192
Query: 624 LQSRLDFAK 650
RL AK
Sbjct: 193 SSYRLTKAK 201
Score = 47.6 bits (108), Expect = 3e-04
Identities = 38/142 (26%), Positives = 62/142 (43%), Gaps = 1/142 (0%)
Frame = +1
Query: 91 PEISDDEVLLRMDCVGICGSDVH-YWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKSRI* 267
P I E L+++ GICG+D+ Y+ K H + P+ MGHE SGV+ +I ++
Sbjct: 20 PVIKKGEALVKVSHAGICGTDMMIYFGK----HPRAQAPLTMGHEFSGVIEEIRGETEF- 74
Query: 268 QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADFCFKLPDH 447
L P GT + + Q G ++ + LP+
Sbjct: 75 SLGDRVAVEPTLSCGTCEACVKGQFHVCKQLKLIGIDQ-DGGFAQHVAVPVNRLHLLPEK 133
Query: 448 VTMEEGALLEPLAVGIHACKRA 513
++ E AL EP+AV +H +R+
Sbjct: 134 LSSEHAALAEPVAVAVHTVRRS 155
>UniRef50_A1UPQ2 Cluster: Alcohol dehydrogenase GroES domain
protein; n=10; Mycobacterium|Rep: Alcohol dehydrogenase
GroES domain protein - Mycobacterium sp. (strain KMS)
Length = 341
Score = 68.9 bits (161), Expect = 1e-10
Identities = 50/157 (31%), Positives = 74/157 (47%), Gaps = 5/157 (3%)
Frame = +1
Query: 61 NDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 240
ND+ L P P D EV++ + G+CG+D+H + G + P+++GHE SG +
Sbjct: 10 NDVGLTSVPDPAPQDGEVIIEVAATGLCGTDLHEYVAGPT---FSQPPVVLGHEVSGRIV 66
Query: 241 KIGS---KSRI*Q--LVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRY 405
++G+ +SRI Q VI +C S P R +G L Y
Sbjct: 67 EVGAGVDQSRIGQGAAVIPMDFCGSCHYCHRSLYH---LCQRPGWIGFTR---NGGLANY 120
Query: 406 YKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
+ ++PD V +EE AL EP AV HA +RAE
Sbjct: 121 VAVPSRLAVRVPDVVDLEEAALTEPTAVAFHAVRRAE 157
Score = 41.5 bits (93), Expect = 0.017
Identities = 33/131 (25%), Positives = 52/131 (39%), Gaps = 2/131 (1%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKP--RQILQARSRFLLQAS* 443
+G A+ P C C +C YHLC + TR + SR ++
Sbjct: 77 IGQGAAVIPMDFCGSCHYCHRSLYHLCQRPGWIG---FTRNGGLANYVAVPSRLAVRVPD 133
Query: 444 SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDI 623
D + T V+ + G V+VLGAG +GL + A+A GA ++ + +
Sbjct: 134 VVDLEEAALTEPTAVAFHAVRRAELLLGETVMVLGAGALGLTVIQCARAAGAARIFVTEP 193
Query: 624 LQSRLDFAKSL 656
R A+ L
Sbjct: 194 SGVRASLARDL 204
>UniRef50_Q01VI1 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Solibacter usitatus Ellin6076|Rep: Alcohol
dehydrogenase GroES domain protein - Solibacter usitatus
(strain Ellin6076)
Length = 343
Score = 68.5 bits (160), Expect = 1e-10
Identities = 47/163 (28%), Positives = 70/163 (42%), Gaps = 4/163 (2%)
Frame = +1
Query: 37 LTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 216
L A L R + PI + EV +R++ VGICGSD+H + +G G E PM++G
Sbjct: 2 LVAELIAQRQFRFTEIPIEDPGPGEVQVRVNAVGICGSDLHSYAEGAIGDTPCEYPMVLG 61
Query: 217 HEASGVVAK----IGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQL 384
HE +G V K +G SR + +E PA R P
Sbjct: 62 HEPAGTVVKTGTGVGGWSRGDRAALE----PALYCYHCEFCRSGRHNICANIRFLSNPGT 117
Query: 385 HGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
G + +P +++E ++EPLAV +H+ K A
Sbjct: 118 PGFFREFVNLPVSNLLAIPPELSLELATIVEPLAVALHSLKFA 160
Score = 64.1 bits (149), Expect = 3e-09
Identities = 35/125 (28%), Positives = 60/125 (48%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SRD 452
GDR A+EP + C +CEFC++GR+++C ++ F + P R+ + LL
Sbjct: 81 GDRAALEPALYCYHCEFCRSGRHNICANIRFLSNPGTPGFFREFVNLPVSNLLAIPPELS 140
Query: 453 HGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQS 632
+ ++ + V V GAGPIGLLT+ K GA ++ +++ +
Sbjct: 141 LELATIVEPLAVALHSLKFAAIQPRETVAVFGAGPIGLLTIACLKDAGAGRIWVVEPVSH 200
Query: 633 RLDFA 647
R + A
Sbjct: 201 RRELA 205
>UniRef50_Q4LED8 Cluster: Dehydrogenase; n=1; uncultured
crenarchaeote 10-H-08|Rep: Dehydrogenase - uncultured
crenarchaeote 10-H-08
Length = 366
Score = 68.5 bits (160), Expect = 1e-10
Identities = 46/143 (32%), Positives = 67/143 (46%), Gaps = 8/143 (5%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM--------IFCATPPVTRKPRQIL 407
EV + VGD V PC YC +CK GR++LC ++ + A + PR+I+
Sbjct: 92 EVDWVNVGDEVVAANSAPCGYCIYCKLGRFNLCENLGETIIGFSVDGAYAEYIKLPRRIV 151
Query: 408 QARSRFLLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAK 587
L + R G + + G V V+GAGPIGLL ML ++
Sbjct: 152 TFNLYKLPKGLEPRVAALLEPLACVVRGQRLIH---IDVGDAVAVVGAGPIGLLHMLLSR 208
Query: 588 AFGAHKVLIIDILQSRLDFAKSL 656
GA KV+++D+ +RL FA L
Sbjct: 209 LSGARKVIVLDVNWNRLRFASEL 231
Score = 47.6 bits (108), Expect = 3e-04
Identities = 25/71 (35%), Positives = 39/71 (54%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A+ + P DLR++ P EVL+R CG+D+ + +G H P+IMGHE
Sbjct: 25 AVFHGPGDLRVMDVGRPSPGRGEVLVRTFVTLTCGTDLKMFLRG---HPYARPPVIMGHE 81
Query: 223 ASGVVAKIGSK 255
+GVV ++G +
Sbjct: 82 FAGVVVEVGEE 92
>UniRef50_Q01PH7 Cluster: Alcohol dehydrogenase GroES domain
protein; n=3; Bacteria|Rep: Alcohol dehydrogenase GroES
domain protein - Solibacter usitatus (strain Ellin6076)
Length = 343
Score = 68.1 bits (159), Expect = 2e-10
Identities = 51/157 (32%), Positives = 75/157 (47%), Gaps = 5/157 (3%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 225
LL + L +V+ P+P I D+VL+R+ GICGSDVH G+ G + P++MGHEA
Sbjct: 5 LLTQYMHLEMVEMPVPAIGADDVLVRVRACGICGSDVH-GLDGKTGRRI--PPLVMGHEA 61
Query: 226 SGVVAKIGSK---SRI*QLVI--EWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHG 390
+G V + G+ R V C T V D S P + HG
Sbjct: 62 AGEVVETGANVTDLRPGDRVTFDSTVYCGRCFHCTRGEVNLCDNREVLGVSPGPY-RRHG 120
Query: 391 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHA 501
Y ++LPD ++ E+ AL+E ++V +HA
Sbjct: 121 AFAEYVSVPRRIMYRLPDSLSYEQAALIEAVSVAVHA 157
Score = 46.0 bits (104), Expect = 8e-04
Identities = 37/135 (27%), Positives = 58/135 (42%), Gaps = 4/135 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVTRKP---RQILQARSR 422
V +L GDRV + V C C C G +LC + + +P R+ + + R
Sbjct: 72 VTDLRPGDRVTFDSTVYCGRCFHCTRGEVNLCDNREVLGVSPGPYRRHGAFAEYVSVPRR 131
Query: 423 FLLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAH 602
+ + S + + + A V V G +V+G+G IGLL M AK G
Sbjct: 132 IMYRLPDSLSYEQAALIEAVSVAVHAVNLTPVRLGDSAVVVGSGMIGLLAMQAAKHAGCT 191
Query: 603 KVLIIDILQSRLDFA 647
+V+ +D + RL A
Sbjct: 192 RVIAVDPDEGRLRLA 206
>UniRef50_P39346 Cluster: L-idonate 5-dehydrogenase; n=17;
Gammaproteobacteria|Rep: L-idonate 5-dehydrogenase -
Escherichia coli (strain K12)
Length = 343
Score = 68.1 bits (159), Expect = 2e-10
Identities = 44/140 (31%), Positives = 67/140 (47%), Gaps = 2/140 (1%)
Frame = +1
Query: 100 SDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASG-VVAKIGSKSRI*QLV 276
+++ L+++ GICGSD+HY+Q+G+ G+F+++ PM++GHE G V+ S+ Q V
Sbjct: 26 NNNGTLVQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKVIHSDSSELHEGQTV 85
Query: 277 IEWP*SPACRVGTASSVRQDDTTYAPT*SSAPR-PQLHGNLVRYYKHAADFCFKLPDHVT 453
P P ++ T SA P + G RY C P
Sbjct: 86 AINPSKPCGHCKYCIEHNENQCTDMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYPAKAD 145
Query: 454 MEEGALLEPLAVGIHACKRA 513
+ A EPLAV IHA +A
Sbjct: 146 EKVMAFAEPLAVAIHAAHQA 165
Score = 43.6 bits (98), Expect = 0.004
Identities = 35/133 (26%), Positives = 55/133 (41%), Gaps = 5/133 (3%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT----PPVTRK-PRQILQARSRFLLQA 437
G VAI P PC +C++C + C DM F + P V R + S+ +
Sbjct: 82 GQTVAINPSKPCGHCKYCIEHNENQCTDMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYP 141
Query: 438 S*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLII 617
+ + + A H+ Q G + G V + G GPIG L + K GA +++
Sbjct: 142 AKADEKVMAFAEPLAVAIHAAHQAGELQ-GKRVFISGVGPIGCLIVSAVKTLGAAEIVCA 200
Query: 618 DILQSRLDFAKSL 656
D+ L K +
Sbjct: 201 DVSPRSLSLGKEM 213
>UniRef50_A3DCE7 Cluster: Alcohol dehydrogenase GroES-like protein;
n=1; Clostridium thermocellum ATCC 27405|Rep: Alcohol
dehydrogenase GroES-like protein - Clostridium
thermocellum (strain ATCC 27405 / DSM 1237)
Length = 344
Score = 67.7 bits (158), Expect = 2e-10
Identities = 45/133 (33%), Positives = 68/133 (51%), Gaps = 1/133 (0%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQI-LQARSRFL 428
+V++L VG +V IEP V C C C+TG+Y+LC ++ V + A++
Sbjct: 71 DVEHLKVGQKVTIEPQVVCGKCHPCRTGKYNLCEELKVMGFQTVGAGSEYFAVDAKNVTT 130
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
+ S D A H+ + G V +V V+GAGPIG+L + T KA GA KV
Sbjct: 131 VPDHLSYDEAAMIEPLAVT-VHAANRVGDVKDKDIV-VIGAGPIGILLVQTLKAKGARKV 188
Query: 609 LIIDILQSRLDFA 647
++ D+ RL+ A
Sbjct: 189 MVTDVSDYRLELA 201
Score = 61.3 bits (142), Expect = 2e-08
Identities = 42/164 (25%), Positives = 72/164 (43%)
Frame = +1
Query: 37 LTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 216
L +++ P + + PE+ +VL+++ +GICGSD+H G+ H + P+ G
Sbjct: 2 LQSVMVSPGKIEFHEVEKPELKPGQVLIKIMRIGICGSDIHV-NHGK--HPFTKYPVTQG 58
Query: 217 HEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNL 396
HE SG + ++ ++ + P G R Q G
Sbjct: 59 HEVSGKIVEVAEDVEHLKVGQKVTIEPQVVCGKCHPCRTGKYNLCEE-LKVMGFQTVGAG 117
Query: 397 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESRRD 528
Y+ A +PDH++ +E A++EPLAV +HA R +D
Sbjct: 118 SEYFAVDAKNVTTVPDHLSYDEAAMIEPLAVTVHAANRVGDVKD 161
>UniRef50_A1SCW8 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=1; Nocardioides sp. JS614|Rep: Alcohol
dehydrogenase, zinc-binding domain protein -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 338
Score = 67.7 bits (158), Expect = 2e-10
Identities = 52/165 (31%), Positives = 71/165 (43%), Gaps = 3/165 (1%)
Frame = +1
Query: 37 LTALLYKPNDLRLVQT---PIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPM 207
+ A L+ DLR+ Q P P + V + VG+CGSD+H++ G G L+ P+
Sbjct: 3 VAARLHSVGDLRVEQVAEPPAPTVGWSTVAVTS--VGLCGSDLHWFTDGGTGEVTLDRPV 60
Query: 208 IMGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLH 387
+ GHE +G R ++ I+ PA G R P A L
Sbjct: 61 VPGHELAGRALDGPYAGR--RVAID----PAIPCGVCEQCRAGHGNLCPDVRFAGHAGLD 114
Query: 388 GNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESR 522
G L F LPD ++ + GALLEPL V IHA A R
Sbjct: 115 GGLQERLVWPDHLLFPLPDDLSDDAGALLEPLGVAIHAVGVAHVR 159
Score = 67.7 bits (158), Expect = 2e-10
Identities = 47/129 (36%), Positives = 64/129 (49%), Gaps = 3/129 (2%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVT--RKPRQILQARSRFLLQAS*S 446
G RVAI+P +PC CE C+ G +LCPD+ F + + R + F L S
Sbjct: 77 GRRVAIDPAIPCGVCEQCRAGHGNLCPDVRFAGHAGLDGGLQERLVWPDHLLFPLPDDLS 136
Query: 447 RDHGRRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDI 623
D G A P G V V GH VLV+G GPIG+LT A+ GA +V++ +
Sbjct: 137 DDAG---ALLEPLGVAIHAVGVAHVRPGHDVLVVGGGPIGVLTAAVARRTGAAQVVVSEP 193
Query: 624 LQSRLDFAK 650
L R + A+
Sbjct: 194 LAHRRETAR 202
>UniRef50_A5FZ32 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Acidiphilium cryptum JF-5|Rep: Alcohol
dehydrogenase GroES domain protein - Acidiphilium
cryptum (strain JF-5)
Length = 339
Score = 67.3 bits (157), Expect = 3e-10
Identities = 43/153 (28%), Positives = 67/153 (43%)
Frame = +1
Query: 64 DLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 243
D+ + P P +D + + + VG+CGSD+HY+ +G G V+ EP + GHE + V +
Sbjct: 11 DITIGDAPEPVPGNDRIAVEVAGVGVCGSDLHYYLEGSIGSQVIVEPFVPGHEFAARVIE 70
Query: 244 IGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAAD 423
+ + + + PA G + + P P G +
Sbjct: 71 ARPELGLAKGEL-IAVDPAMPCGHCEWCHRGEINLCPDTVFNGAPPYPGAMAERMAIEPR 129
Query: 424 FCFKLPDHVTMEEGALLEPLAVGIHACKRAESR 522
K+P H T+EE +LEPL V IHA A R
Sbjct: 130 QVVKVPQHFTIEETMMLEPLGVAIHAIDLARPR 162
Score = 63.7 bits (148), Expect = 4e-09
Identities = 42/139 (30%), Positives = 68/139 (48%), Gaps = 8/139 (5%)
Frame = +3
Query: 264 LTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPP--------VTRKPRQILQARS 419
L G+ +A++P +PC +CE+C G +LCPD +F PP + +PRQ+++
Sbjct: 77 LAKGELIAVDPAMPCGHCEWCHRGEINLCPDTVFNGAPPYPGAMAERMAIEPRQVVKVPQ 136
Query: 420 RFLLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGA 599
F ++ + + A A R+ E V V+G GPIGLL + A+ G
Sbjct: 137 HFTIEETMMLE-PLGVAIHAIDLARPRLLES-------VAVIGCGPIGLLMIALARLAGV 188
Query: 600 HKVLIIDILQSRLDFAKSL 656
++L ID + R A +L
Sbjct: 189 GQILAIDPVDYRRAHAGAL 207
>UniRef50_A3S6P0 Cluster: L-threonine 3-dehydrogenase; n=2;
Bacteria|Rep: L-threonine 3-dehydrogenase -
Prochlorococcus marinus str. MIT 9211
Length = 379
Score = 67.3 bits (157), Expect = 3e-10
Identities = 45/145 (31%), Positives = 67/145 (46%), Gaps = 1/145 (0%)
Frame = +1
Query: 67 LRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 246
L +VQ P+PEI DEVL+++ GICG+D+H W + PMI GHE +G + +I
Sbjct: 50 LWMVQAPVPEIGPDEVLIKVRKTGICGTDIHIWNWDDWASATVPTPMITGHEFAGEIVEI 109
Query: 247 GSKSRI*QLVIEWP*S-PACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAAD 423
G + L I S +GT S + + + G +Y + A
Sbjct: 110 GRD--VTGLSIGQRCSGEGHLIGTDSRQSRAGKFHLDPGTRGIGVNEQGAFAQYLRLPAF 167
Query: 424 FCFKLPDHVTMEEGALLEPLAVGIH 498
LP + E GA+L+PL +H
Sbjct: 168 NVVPLPASIPDEIGAILDPLGNAVH 192
Score = 39.1 bits (87), Expect = 0.092
Identities = 19/42 (45%), Positives = 25/42 (59%)
Frame = +3
Query: 525 GHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAK 650
G VL+ GAGPIG++ A+ GA V+I DI RL A+
Sbjct: 201 GEDVLITGAGPIGIMAAAVARHAGARNVVITDINPDRLKLAE 242
>UniRef50_Q88S92 Cluster: L-iditol 2-dehydrogenase; n=7;
Firmicutes|Rep: L-iditol 2-dehydrogenase - Lactobacillus
plantarum
Length = 352
Score = 66.9 bits (156), Expect = 4e-10
Identities = 44/148 (29%), Positives = 75/148 (50%), Gaps = 1/148 (0%)
Frame = +1
Query: 61 NDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 240
+++ L Q PIPE++ D+VLL++ GICG+D+H + KGQ + V P+++GHE SG V
Sbjct: 12 DNMELKQIPIPEVTGDKVLLKVAYTGICGTDIHTF-KGQYANAV--TPLVLGHEFSGEVV 68
Query: 241 KIGSKSRI*QLVIEWP*SPACRV-GTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHA 417
++G + + GT + + P + +G++ Y
Sbjct: 69 EVGPDVKTLKPGDRVTSETTFATDGTCVYCQDKEYNLCPN-RVGIGTKANGSMANYVLTR 127
Query: 418 ADFCFKLPDHVTMEEGALLEPLAVGIHA 501
+ LPD+V+ + A+ EPLA +HA
Sbjct: 128 EESAHILPDNVSYKMAAMSEPLASCVHA 155
Score = 47.2 bits (107), Expect = 3e-04
Identities = 41/141 (29%), Positives = 65/141 (46%), Gaps = 6/141 (4%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCR-YCEFCKTGRYHLCPDMIFCATPPVTRKPRQIL-QARSRF 425
+VK L GDRV E C +C+ Y+LCP+ + T +L + S
Sbjct: 73 DVKTLKPGDRVTSETTFATDGTCVYCQDKEYNLCPNRVGIGTKANGSMANYVLTREESAH 132
Query: 426 LLQAS*SRDHGRRSATGAPRGG--HSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGA 599
+L + S + +A P H+ Q+ + +L++G GP+GLL++ AK GA
Sbjct: 133 ILPDNVSY---KMAAMSEPLASCVHAMYQKTPFTLHDTLLIMGPGPMGLLSLQIAKEIGA 189
Query: 600 HKVLIIDILQ--SRLDFAKSL 656
V++ I + RL AK L
Sbjct: 190 F-VIVSGITKDADRLQIAKEL 209
>UniRef50_A0QWX1 Cluster: Oxidoreductase, zinc-binding dehydrogenase
family protein; n=3; Bacteria|Rep: Oxidoreductase,
zinc-binding dehydrogenase family protein -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 363
Score = 66.9 bits (156), Expect = 4e-10
Identities = 37/132 (28%), Positives = 64/132 (48%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V+ +G+ V++ P +PCR C+FC G + LC + + + + ++ L
Sbjct: 91 VEGFDIGELVSVPPLIPCRRCDFCAKGEFGLCENYDYFGSRSDGAYAQYVVSPVGNLLKL 150
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
+ A H + + G+ AGH VLV+GAGPIGL + AK GA +V+
Sbjct: 151 PAGIDPRAAAMLDPAAIALHG-LWKTGLRAGHRVLVIGAGPIGLFAIQWAKLHGADQVVA 209
Query: 615 IDILQSRLDFAK 650
+D+ + + A+
Sbjct: 210 VDLSEEKAAMAR 221
Score = 57.6 bits (133), Expect = 2e-07
Identities = 28/69 (40%), Positives = 43/69 (62%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A++Y P D+R+ Q P+P EVLL++ G+CGSD+ + G +V+ P+I GHE
Sbjct: 24 AVMYAPGDIRVEQAPVPRPGPGEVLLKVAACGVCGSDIPRMLRN--GGYVM--PIICGHE 79
Query: 223 ASGVVAKIG 249
SG V ++G
Sbjct: 80 FSGWVVELG 88
>UniRef50_Q5K658 Cluster: Sorbitol dehydrogenase; n=2; Dikarya|Rep:
Sorbitol dehydrogenase - Paracoccidioides brasiliensis
Length = 124
Score = 66.9 bits (156), Expect = 4e-10
Identities = 26/68 (38%), Positives = 43/68 (63%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 225
+L+ P DLRL P E+ + + G+CGSD+HY+ G+ G F+++ P+ +GHE+
Sbjct: 14 VLHAPRDLRLESRLTPAPKHGELQIAIRATGLCGSDLHYYNHGRNGDFIVQSPLCLGHES 73
Query: 226 SGVVAKIG 249
SG++ IG
Sbjct: 74 SGIITAIG 81
Score = 44.4 bits (100), Expect = 0.002
Identities = 16/32 (50%), Positives = 22/32 (68%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIF 365
+GDRVA+E G+PC C C GRY++C + F
Sbjct: 90 IGDRVALEVGLPCHSCPLCLQGRYNICRKLRF 121
>UniRef50_A2R6Z1 Cluster: Catalytic activity: L-iditol + NAD(+) <=>
L-sorbose + NADH; n=1; Aspergillus niger|Rep: Catalytic
activity: L-iditol + NAD(+) <=> L-sorbose + NADH -
Aspergillus niger
Length = 159
Score = 66.9 bits (156), Expect = 4e-10
Identities = 27/55 (49%), Positives = 40/55 (72%), Gaps = 1/55 (1%)
Frame = +1
Query: 88 IPEI-SDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIG 249
IP I SD +VL+R+ G+CGSD+HYWQ G+ G + + +P+I+ HE+SGV+ G
Sbjct: 27 IPTIESDRDVLVRVVATGLCGSDIHYWQHGKLGEYEVTQPLILAHESSGVIVATG 81
Score = 45.6 bits (103), Expect = 0.001
Identities = 16/31 (51%), Positives = 22/31 (70%)
Frame = +3
Query: 258 KNLTVGDRVAIEPGVPCRYCEFCKTGRYHLC 350
+ L + DRVA+EP PC C +C++GRY LC
Sbjct: 85 QGLKINDRVALEPRNPCNVCPYCRSGRYKLC 115
>UniRef50_Q5LVU9 Cluster: Sorbitol dehydrogenase, putative; n=13;
Alphaproteobacteria|Rep: Sorbitol dehydrogenase,
putative - Silicibacter pomeroyi
Length = 332
Score = 66.1 bits (154), Expect = 7e-10
Identities = 48/159 (30%), Positives = 70/159 (44%), Gaps = 2/159 (1%)
Frame = +1
Query: 37 LTALLYK-PNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLE-EPMI 210
+ AL+Y P L L + P P E L+R+ VGICGSD+H + GH P+I
Sbjct: 1 MKALVYTGPETLALREMPNPVAGPGEQLIRIARVGICGSDMHAY----LGHDARRPAPLI 56
Query: 211 MGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHG 390
+GHE +GV+ +G ++ + +P G + R+ PT P G
Sbjct: 57 LGHEVAGVI--VGGPRDGERVTV----NPLVTCGACPACREGRDNLCPTRQIISMPPREG 110
Query: 391 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACK 507
Y +PD V + + AL EPLA G H +
Sbjct: 111 GFAEYVAMPEGNLVTVPDSVPLAQAALAEPLACGWHTVR 149
Score = 42.7 bits (96), Expect = 0.007
Identities = 35/119 (29%), Positives = 52/119 (43%), Gaps = 3/119 (2%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SRD 452
G+RV + P V C C C+ GR +LCP + PP + + L+ S
Sbjct: 72 GERVTVNPLVTCGACPACREGRDNLCPTRQIISMPPREGGFAEYVAMPEGNLVTVPDSVP 131
Query: 453 HGRRS-ATGAPRGGHS-RVQEGGVS-AGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIID 620
+ + A G H+ R+ +S A LVLG G IGL L A G +V +++
Sbjct: 132 LAQAALAEPLACGWHTVRLSLAALSGARDTALVLGGGAIGLGAALCLTAQGVPQVTVVE 190
>UniRef50_A5V1N3 Cluster: Alcohol dehydrogenase GroES domain
protein; n=2; Roseiflexus|Rep: Alcohol dehydrogenase
GroES domain protein - Roseiflexus sp. RS-1
Length = 345
Score = 66.1 bits (154), Expect = 7e-10
Identities = 56/171 (32%), Positives = 78/171 (45%), Gaps = 11/171 (6%)
Frame = +1
Query: 22 MATDNLTALLYK-PNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLE 198
M T + AL++ P + L + P P EVL+ ++ VGICGS++ G G L
Sbjct: 1 MMTSTMDALVWLGPRRMELRREPAPTPEPGEVLVAVEAVGICGSEL----SGYLGQNSLR 56
Query: 199 E-PMIMGHEASGVVA-------KIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAP 354
+ P+IMGHEA+G +A GS +R + +P G R +
Sbjct: 57 KPPLIMGHEAAGRIAFDSDAALSDGSPAR---AGVRVTFNPLLTCGACDRCRAGKSNLCR 113
Query: 355 T*S--SAPRPQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHA 501
SA RP G Y AD C LPDHV++ G+L EPLA + A
Sbjct: 114 NRQLISAHRP---GAFATYVAVPADLCIPLPDHVSLTLGSLTEPLACSVRA 161
Score = 41.5 bits (93), Expect = 0.017
Identities = 37/128 (28%), Positives = 55/128 (42%), Gaps = 1/128 (0%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPD-MIFCATPPVTRKPRQILQARSRFLLQAS*SR 449
G RV P + C C+ C+ G+ +LC + + A P + A L S
Sbjct: 87 GVRVTFNPLLTCGACDRCRAGKSNLCRNRQLISAHRPGAFATYVAVPADLCIPLPDHVSL 146
Query: 450 DHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQ 629
G S T V G + +LGAGPIGLL ++ A+A G +L+ D+
Sbjct: 147 TLG--SLTEPLACSVRAVAHTGTPER--LAILGAGPIGLLCLVAARAAGIEHILMSDVSD 202
Query: 630 SRLDFAKS 653
RL A++
Sbjct: 203 RRLAVARA 210
>UniRef50_Q8ZJN2 Cluster: L-threonine 3-dehydrogenase; n=41;
Bacteria|Rep: L-threonine 3-dehydrogenase - Yersinia
pestis
Length = 341
Score = 65.7 bits (153), Expect = 9e-10
Identities = 43/136 (31%), Positives = 65/136 (47%), Gaps = 1/136 (0%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATP-PVTRKPRQILQARSRFL 428
EVK +GDRV+ E + C +C C+ GR HLC + + P + ++ A + F
Sbjct: 75 EVKGFNIGDRVSGEGHITCGHCRNCRGGRTHLCRNTVGVGVNRPGSFAEYLVIPAFNAFK 134
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
+ + S + +A P G G VLV GAGPIG++ K GA V
Sbjct: 135 IPDNISDE---LAAIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGIMAAAVCKHVGARHV 191
Query: 609 LIIDILQSRLDFAKSL 656
+I D+ + RLD A+ +
Sbjct: 192 VIADVNEYRLDLARKM 207
Score = 52.0 bits (119), Expect = 1e-05
Identities = 32/142 (22%), Positives = 61/142 (42%)
Frame = +1
Query: 73 LVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 252
+ P PE+ +++++++ ICG+DVH + + + PM++GHE G V IG
Sbjct: 15 MTDVPQPELGHNDIMIKIRKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVAIGQ 74
Query: 253 KSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADFCF 432
+ + + G + R T+ + G+ Y A F
Sbjct: 75 EVKGFNIGDRVSGEGHITCGHCRNCR-GGRTHLCRNTVGVGVNRPGSFAEYLVIPAFNAF 133
Query: 433 KLPDHVTMEEGALLEPLAVGIH 498
K+PD+++ E A+ +P +H
Sbjct: 134 KIPDNISDELAAIFDPFGNAVH 155
>UniRef50_Q6NDJ8 Cluster: Putative Zn-binding dehydrogenase; n=1;
Rhodopseudomonas palustris|Rep: Putative Zn-binding
dehydrogenase - Rhodopseudomonas palustris
Length = 346
Score = 65.3 bits (152), Expect = 1e-09
Identities = 52/160 (32%), Positives = 77/160 (48%), Gaps = 5/160 (3%)
Frame = +1
Query: 37 LTALLYKPNDLRLVQTPI--PEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 210
+ A +++ RLV + P + D+E+LL++ GICGSD+H + +L+ +
Sbjct: 1 MKAAVFEKTGERLVVRDVAAPALGDNELLLKVAFTGICGSDLHAAETPG----MLQSGTV 56
Query: 211 MGHEASG-VVAKIGSKSRI*QLVIEWP*--SPACRVGTASSVRQDDTTYAPT*SSAPRPQ 381
MGHE +G +V S + V P AC G + S D A RP
Sbjct: 57 MGHEFTGEIVQSTASDWPVGARVAANPYWLCDACAAGGSCS-GGGDAACANGSFMGFRPD 115
Query: 382 LHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHA 501
L G Y + A +LPD V++ +GAL+EPLAV HA
Sbjct: 116 LPGAYADYVRIRAGQAIRLPDKVSLRDGALMEPLAVARHA 155
>UniRef50_A4XEZ1 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=1; Novosphingobium aromaticivorans DSM
12444|Rep: Alcohol dehydrogenase, zinc-binding domain
protein - Novosphingobium aromaticivorans (strain DSM
12444)
Length = 347
Score = 65.3 bits (152), Expect = 1e-09
Identities = 47/163 (28%), Positives = 74/163 (45%), Gaps = 1/163 (0%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHF-VLEEPMIMGH 219
A ++ P D+RL + P+P E L+++ G+CGSD+ Y +G G L P+ +GH
Sbjct: 10 ARVHGPGDVRLDEVPVPHCGPGEALVQVAACGVCGSDLGYIAQGGLGGVEPLSAPLPIGH 69
Query: 220 EASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLV 399
E +G V +G Q V +P RV D Y P + +
Sbjct: 70 EFAGTVVAVG------QCVTSV--APGMRVAV-----NPDRAYIG--GGGPDGAMAAFIR 114
Query: 400 RYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESRRD 528
+ F LPDH+ E +L EPL+VG+H + A ++ +
Sbjct: 115 VAGAEIGETLFPLPDHLPFAEASLAEPLSVGLHGLRVAGAKTE 157
Score = 39.9 bits (89), Expect = 0.053
Identities = 18/41 (43%), Positives = 27/41 (65%)
Frame = +3
Query: 534 VLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
+ +LGAGPIGL ++ A+ GA V I D + RL+ A++L
Sbjct: 160 IAILGAGPIGLCALVMARHLGARDVAIFDRVPERLERARAL 200
>UniRef50_Q5B6Y0 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 351
Score = 65.3 bits (152), Expect = 1e-09
Identities = 46/143 (32%), Positives = 65/143 (45%), Gaps = 9/143 (6%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPC--RYCE------FCKTGRYHLCPDMIFCATPPVTRKPRQIL 407
EVK+ VG R+A+EPG C R C FC G + C ++ +C P +Q
Sbjct: 75 EVKDRHVGQRMAVEPGFACATRKCPDNQEDAFCLRGNPNTCANLKYCGLDPTDGTLQQYF 134
Query: 408 QARSRFLLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSA-GHVVLVLGAGPIGLLTMLTA 584
++ + A + +SA VV G GP+GLL + A
Sbjct: 135 TCKAHMAIPIPEEISWEEAGAIQPLAIAVQLARRAALSATAKVVGDGGCGPLGLLVIAIA 194
Query: 585 KAFGAHKVLIIDILQSRLDFAKS 653
KA+G K+++ DI QSRLDFA S
Sbjct: 195 KAYGVCKIVVFDIEQSRLDFALS 217
Score = 48.8 bits (111), Expect = 1e-04
Identities = 39/161 (24%), Positives = 69/161 (42%), Gaps = 12/161 (7%)
Frame = +1
Query: 67 LRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS---GVV 237
L + P+ +EVL+++ GICGSD H W + +I+GHE++ G++
Sbjct: 15 LAIQDRPVTPPGPNEVLVQVISTGICGSDTHNWNNPN-----VSRELILGHESAGLRGLI 69
Query: 238 AKIGSKSRI*QLVIEWP*SPACRVGT---------ASSVRQDDTTYAPT*SSAPRPQLHG 390
+I S+ + + P T A +R + T A P G
Sbjct: 70 VEIDSEVKDRHVGQRMAVEPGFACATRKCPDNQEDAFCLRGNPNTCANLKYCGLDP-TDG 128
Query: 391 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
L +Y+ A +P+ ++ EE ++PLA+ + +RA
Sbjct: 129 TLQQYFTCKAHMAIPIPEEISWEEAGAIQPLAIAVQLARRA 169
>UniRef50_A5D1M5 Cluster: Threonine dehydrogenase and related
Zn-dependent dehydrogenases; n=1; Pelotomaculum
thermopropionicum SI|Rep: Threonine dehydrogenase and
related Zn-dependent dehydrogenases - Pelotomaculum
thermopropionicum SI
Length = 329
Score = 64.9 bits (151), Expect = 2e-09
Identities = 46/160 (28%), Positives = 73/160 (45%)
Frame = +1
Query: 37 LTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 216
L Y D+R+ P P DEVL+++ GICGSD+H ++KG F+ P+ MG
Sbjct: 2 LAVRYYGIGDIRVENIPKPAPGHDEVLVKVAYAGICGSDLHIFRKGM---FISSAPVTMG 58
Query: 217 HEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNL 396
HE SGVV ++G+ + + P G R++ P + G
Sbjct: 59 HEFSGVVEEVGAGVTGLRPGDQVVGDPRVPCGRCQWCRREQYNLCPGLGFIGEVR-PGCF 117
Query: 397 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
+ K+P + ++E L+EPLAV +H K+ +
Sbjct: 118 AEHIAINYKKLLKVP-ALDLKEAVLVEPLAVAVHIAKKGK 156
Score = 63.3 bits (147), Expect = 5e-09
Identities = 40/135 (29%), Positives = 67/135 (49%), Gaps = 1/135 (0%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V L GD+V +P VPC C++C+ +Y+LCP + F I + L
Sbjct: 72 VTGLRPGDQVVGDPRVPCGRCQWCRREQYNLCPGLGFIGEVRPGCFAEHIAINYKKLLKV 131
Query: 435 AS*SRDHGRRSATGAPRGGHSRV-QEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVL 611
+ + + P + ++G +S + V +LGAGPIGLLT+ AKA +V+
Sbjct: 132 PALDL---KEAVLVEPLAVAVHIAKKGKLSPENTVGILGAGPIGLLTLAAAKAIRVREVI 188
Query: 612 IIDILQSRLDFAKSL 656
++D +RL+ A+ +
Sbjct: 189 VVDPSPARLEIARKI 203
>UniRef50_Q9VDQ9 Cluster: CG4836-PC, isoform C; n=4; Eukaryota|Rep:
CG4836-PC, isoform C - Drosophila melanogaster (Fruit
fly)
Length = 1217
Score = 64.9 bits (151), Expect = 2e-09
Identities = 46/159 (28%), Positives = 74/159 (46%)
Frame = +1
Query: 37 LTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 216
LT + P ++ +V P D +VL+R V + SD+H ++ G E M +G
Sbjct: 877 LTLRITNPYEISVVPFSKPRPKDFDVLIRTGSVAVSNSDIHVYENGNRDM----EAMSLG 932
Query: 217 HEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNL 396
H+A+G+V ++G + V + +A S D + +G L
Sbjct: 933 HDATGIVEELG------RCVQHLHVGDRVVMESALSCGICDLCKKGLYNMCSGLVYNGFL 986
Query: 397 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
Y H AD C +LP+ ++ME GAL + LA+G AC +A
Sbjct: 987 STYQTHPADLCHRLPESISMEAGALTQTLALGCQACFKA 1025
Score = 53.2 bits (122), Expect = 5e-06
Identities = 40/129 (31%), Positives = 60/129 (46%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V++L VGDRV +E + C C+ CK G Y++C +++ + L R L
Sbjct: 946 VQHLHVGDRVVMESALSCGICDLCKKGLYNMCSGLVYNGFLSTYQTHPADLCHR----LP 1001
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
S S + G + T A G + V+ VL+LGA P + + AKA GA +V I
Sbjct: 1002 ESISMEAGALTQTLAL--GCQACFKANVTPTSNVLILGACPTAVAAGICAKAIGAKRVAI 1059
Query: 615 IDILQSRLD 641
+ LD
Sbjct: 1060 AGCMAPALD 1068
>UniRef50_Q1HPY0 Cluster: Zinc-containing alcohol dehydrogenase;
n=1; Bombyx mori|Rep: Zinc-containing alcohol
dehydrogenase - Bombyx mori (Silk moth)
Length = 342
Score = 64.9 bits (151), Expect = 2e-09
Identities = 51/150 (34%), Positives = 76/150 (50%), Gaps = 7/150 (4%)
Frame = +1
Query: 85 PIPEI-SDDEVLLRMDCVGICGSDVHYWQKGQCGHFVL--EEPMIMGHEASGVVAKIGSK 255
P+P+I +DD+V+++++ GICG+D+H Q G F E P+ +GHE SG + +G K
Sbjct: 20 PLPKIENDDDVIVKVEYSGICGTDLHIVQ----GEFPASKERPLPLGHEFSGTITDVGKK 75
Query: 256 S--RI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*--SSAPRPQLHGNLVRYYKHAAD 423
S R Q V+ P + AC + R+ Y T +S G +Y K D
Sbjct: 76 SVFRKGQKVVVDP-NRACSL--CDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQD 132
Query: 424 FCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
+ LPD V+ E+G L EP + H RA
Sbjct: 133 QVYLLPDGVSTEQGGLCEPYSCVAHGYDRA 162
Score = 40.7 bits (91), Expect = 0.030
Identities = 30/133 (22%), Positives = 55/133 (41%), Gaps = 5/133 (3%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTR-----KPRQILQARSRFLLQA 437
G +V ++P C C+FC+ G+Y C +T + R + ++ Q + L
Sbjct: 81 GQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQVYLLPDG 140
Query: 438 S*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLII 617
+ G G+ R + G +L++GAG IG L + + G V +
Sbjct: 141 VSTEQGGLCEPYSCVAHGYDRASP--LLVGEKILIVGAGIIGNLWVTSLHQLGHRDVTVS 198
Query: 618 DILQSRLDFAKSL 656
++ + RL+ L
Sbjct: 199 EMNKVRLEIVNKL 211
>UniRef50_Q46NN2 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=1; Ralstonia eutropha JMP134|Rep:
Zinc-containing alcohol dehydrogenase superfamily -
Ralstonia eutropha (strain JMP134) (Alcaligenes
eutrophus)
Length = 367
Score = 64.5 bits (150), Expect = 2e-09
Identities = 53/169 (31%), Positives = 76/169 (44%), Gaps = 11/169 (6%)
Frame = +1
Query: 22 MATDNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE 201
M + L +L P +L+ + PIPEI DD+ +LR++ G+CG+D W G +
Sbjct: 1 MTRNALALVLESPKNLQAREFPIPEIGDDDAVLRVEACGLCGTDYEQW-LGHMKDWGGGM 59
Query: 202 PMIMGHEASGVVAKIGSKS------RI*QLVIEWP*SPA--CR--VGTASSVRQDDTTYA 351
P+I GHE G + +IG+ + R V P P C V A + Q D Y
Sbjct: 60 PIIPGHEIMGFIERIGTLAAKRWNVREGDRVAIEPIIPCGHCEDCVRGAYTRCQSDLGYG 119
Query: 352 PT*SSAPRPQLHGNLVRY-YKHAADFCFKLPDHVTMEEGALLEPLAVGI 495
S+A P L G + Y H KLP + E L+ PL+ I
Sbjct: 120 LYQSTAVAPHLWGGYATHVYLHPRTMVHKLPTDLPTEVMTLVNPLSNAI 168
Score = 41.9 bits (94), Expect = 0.013
Identities = 17/30 (56%), Positives = 20/30 (66%)
Frame = +3
Query: 261 NLTVGDRVAIEPGVPCRYCEFCKTGRYHLC 350
N+ GDRVAIEP +PC +CE C G Y C
Sbjct: 83 NVREGDRVAIEPIIPCGHCEDCVRGAYTRC 112
>UniRef50_A4FHA7 Cluster: Zinc-binding dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: Zinc-binding
dehydrogenase - Saccharopolyspora erythraea (strain NRRL
23338)
Length = 336
Score = 64.5 bits (150), Expect = 2e-09
Identities = 40/158 (25%), Positives = 78/158 (49%), Gaps = 2/158 (1%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHF-VLEEPMIMGH 219
A++ +P +R+ P + +V++++ GICG+D+H GHF P++ GH
Sbjct: 4 AIVDRPGSVRVGDVQDPSPGERDVVIKVGACGICGTDLHIAD----GHFPPTPYPIVPGH 59
Query: 220 EASGVVAKIGSKS-RI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNL 396
E +G V ++GS++ ++ P+ G + R +A ++G
Sbjct: 60 EFAGEVVELGSEAPGGFEIGDRVAVDPSLFCGYCTPCRSGHGNLCAN-WNATGDTVNGAF 118
Query: 397 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKR 510
Y A C+++PD +T E+GAL+EP++ +H ++
Sbjct: 119 AEYVSVPAATCYRMPDEMTWEQGALVEPVSCAVHGVRQ 156
Score = 48.0 bits (109), Expect = 2e-04
Identities = 39/132 (29%), Positives = 63/132 (47%), Gaps = 3/132 (2%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQI-LQARSRFLLQAS*S 446
+GDRVA++P + C YC C++G +LC + + + A + + + +
Sbjct: 78 IGDRVAVDPSLFCGYCTPCRSGHGNLCANWNATGDTVNGAFAEYVSVPAATCYRMPDEMT 137
Query: 447 RDHGR--RSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIID 620
+ G + A G V++ GV AG LV+GAG +GLL + GAH V ++D
Sbjct: 138 WEQGALVEPVSCAVHG----VRQIGVEAGERFLVVGAGTMGLLMQQLLQRGGAH-VTVVD 192
Query: 621 ILQSRLDFAKSL 656
+RL A L
Sbjct: 193 RNTARLGRASRL 204
>UniRef50_A1SFU6 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=1; Nocardioides sp. JS614|Rep: Alcohol
dehydrogenase, zinc-binding domain protein -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 351
Score = 64.1 bits (149), Expect = 3e-09
Identities = 47/169 (27%), Positives = 73/169 (43%), Gaps = 8/169 (4%)
Frame = +1
Query: 28 TDNLTALLYK-PNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP 204
T + AL+ + PN L + + P+PE +EVL R+ V ICG+D H G + + P
Sbjct: 2 TQIMQALVVREPNVLEIAEVPVPEPGRNEVLARVRSVSICGTDAHLINGDYPGFWPPQFP 61
Query: 205 MIMGHEASGVVAKIGSKS-----RI*QLVIEWP*SP--ACRVGTASSVRQDDTTYAPT*S 363
GHE +G V +G + R+ V S AC+ + P
Sbjct: 62 FTPGHEWAGDVVALGEGADTFGWRVGDRVAGTSHSACGACQKCVEGQYNLCENYGRPALH 121
Query: 364 SAPRPQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKR 510
+ G Y H F+LPD V+ + GAL +P ++ +H +R
Sbjct: 122 AQYGHNAQGVNATYAVHNVKSIFRLPDEVSFDVGALADPASIALHVARR 170
>UniRef50_A0TC93 Cluster: Alcohol dehydrogenase GroES-like; n=15;
Proteobacteria|Rep: Alcohol dehydrogenase GroES-like -
Burkholderia ambifaria MC40-6
Length = 358
Score = 64.1 bits (149), Expect = 3e-09
Identities = 48/159 (30%), Positives = 73/159 (45%)
Frame = +1
Query: 37 LTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 216
L+ + P LR P ++ E+LLR+ VGICG+D+H + Q L+ P +MG
Sbjct: 25 LSIICESPGILRHEDRAPPSRAEGEILLRVQRVGICGTDMHIYSGNQP---YLQYPRVMG 81
Query: 217 HEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNL 396
HE S +VA+ + + + P G + RQ T G L
Sbjct: 82 HELSAIVAEADPGAHVAPGDAVYV-MPYLSCGQCIACRQGKTNCCVN-IKVLGVHRDGAL 139
Query: 397 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
Y A F K + VT+++ A++E LA+G HA +RA
Sbjct: 140 TEYLSVPAQFVHK-AEGVTLDQAAMIEFLAIGAHAVRRA 177
Score = 51.6 bits (118), Expect = 2e-05
Identities = 38/126 (30%), Positives = 58/126 (46%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SRD 452
GD V + P + C C C+ G+ + C ++ + L ++F+ +A
Sbjct: 100 GDAVYVMPYLSCGQCIACRQGKTNCCVNIKVLGVHR-DGALTEYLSVPAQFVHKAEGVTL 158
Query: 453 HGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQS 632
G H+ V+ VSAG +LV+GAGPIG+ ML A+ GAH V +D
Sbjct: 159 DQAAMIEFLAIGAHA-VRRAAVSAGQRILVVGAGPIGMAAMLFAQLRGAH-VTCLDTRAD 216
Query: 633 RLDFAK 650
RL F +
Sbjct: 217 RLAFCR 222
>UniRef50_A0JVX4 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Arthrobacter sp. FB24|Rep: Alcohol
dehydrogenase GroES domain protein - Arthrobacter sp.
(strain FB24)
Length = 349
Score = 63.7 bits (148), Expect = 4e-09
Identities = 46/141 (32%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCAT-----PPVTRKPRQILQA 413
EV VGDRV++ P V C C C G ++CP F T R PR L
Sbjct: 73 EVSGYAVGDRVSVTPNVGCGTCPNCLVGLNNMCPSYEAFGITMDGGFQEYVRIPRFALNR 132
Query: 414 RSRFLLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAF 593
+ F L + + + ++ V + V VL++GAGPIG ++ AK +
Sbjct: 133 GNVFHLPETVG--YAEAALVEPLSCCYNAVSKLDVRPDSTVLIMGAGPIGACHVMLAKLY 190
Query: 594 GAHKVLIIDILQSRLDFAKSL 656
GA KV++ + Q RLDFA +L
Sbjct: 191 GARKVIVSNNRQPRLDFAGTL 211
Score = 49.6 bits (113), Expect = 6e-05
Identities = 44/169 (26%), Positives = 74/169 (43%), Gaps = 6/169 (3%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE--PMIMG 216
A L+ P ++R+ P P ++++R+ ICG+D GHF L E P ++G
Sbjct: 4 ARLHSPGNIRVDDIPRPSADAGDIIIRVRAASICGTDRRI---AANGHFKLPEGTPRVLG 60
Query: 217 HEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHG-- 390
HE +G + + GS+ + +P GT + P+ + G
Sbjct: 61 HEFAGEIVEAGSEVSGYAVGDRVSVTPNVGCGTCPNCLVGLNNMCPSYEAFGITMDGGFQ 120
Query: 391 NLVRYYKHAAD--FCFKLPDHVTMEEGALLEPLAVGIHACKRAESRRDT 531
VR + A + F LP+ V E AL+EPL+ +A + + R D+
Sbjct: 121 EYVRIPRFALNRGNVFHLPETVGYAEAALVEPLSCCYNAVSKLDVRPDS 169
>UniRef50_Q24T43 Cluster: Putative uncharacterized protein; n=1;
Desulfitobacterium hafniense Y51|Rep: Putative
uncharacterized protein - Desulfitobacterium hafniense
(strain Y51)
Length = 319
Score = 63.3 bits (147), Expect = 5e-09
Identities = 49/161 (30%), Positives = 76/161 (47%), Gaps = 4/161 (2%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 225
+L+ +DLRL + +P +S EVL+R+ C GIC SDV H+ P+I+GHE
Sbjct: 11 VLHNIDDLRLSEVKLPVLSRGEVLVRVKCAGICSSDVQRVFVSGAYHY----PIILGHEF 66
Query: 226 SGVVAKIGS---KSRI*QLVIEWP*SPA-CRVGTASSVRQDDTTYAPT*SSAPRPQLHGN 393
SG+V K S S I + V +P P G + + + Y S + G
Sbjct: 67 SGIVEKAYSDAEASWIGKRVGVYPLLPKFANEGYRTDGYETSSDYGYLGS-----RQDGG 121
Query: 394 LVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
Y ++P+ + EE A+LEP +V HA ++ +
Sbjct: 122 FAEYVAVPVWNLIEIPEKIGFEEAAMLEPTSVAFHAVRQID 162
>UniRef50_Q9KGB7 Cluster: Sorbitol dehydrogenase; n=28;
Bacillales|Rep: Sorbitol dehydrogenase - Bacillus
halodurans
Length = 354
Score = 62.9 bits (146), Expect = 7e-09
Identities = 49/155 (31%), Positives = 69/155 (44%), Gaps = 1/155 (0%)
Frame = +1
Query: 49 LYKPNDLRLVQTPIPEIS-DDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 225
LY DLR +TP P I DD++++++ VGICGSD+ ++K G +V M GHE
Sbjct: 6 LYGIQDLRFEETPAPSIEHDDDIIIKVKAVGICGSDLSRYKK--LGPYV--PGMTFGHEF 61
Query: 226 SGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRY 405
+G V KIG + P G + + T S + G Y
Sbjct: 62 AGEVVKIGRSVTGFSIGDRVAACPTYTCGQCRYCQLGEPTRCER-LSVIGARHPGAYAEY 120
Query: 406 YKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKR 510
K A LP+ V +E AL+EP +V H R
Sbjct: 121 VKLPAKHVIPLPNVVNYDEAALIEPASVVAHGFYR 155
Score = 48.4 bits (110), Expect = 1e-04
Identities = 40/136 (29%), Positives = 55/136 (40%), Gaps = 2/136 (1%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVTRKPRQILQARSRFLL 431
V ++GDRVA P C C +C+ G C + + A P L A+ L
Sbjct: 72 VTGFSIGDRVAACPTYTCGQCRYCQLGEPTRCERLSVIGARHPGAYAEYVKLPAKHVIPL 131
Query: 432 QAS*SRDHGRR-SATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
+ D G R + G V ++G G IGLL + AK FGA V
Sbjct: 132 PNVVNYDEAALIEPASVVAHGFYRTN---IKPGASVAIMGVGSIGLLAVQWAKIFGATTV 188
Query: 609 LIIDILQSRLDFAKSL 656
IDI + +L+ A L
Sbjct: 189 FAIDIDEQKLNVANQL 204
>UniRef50_Q9UAT1 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 326
Score = 62.9 bits (146), Expect = 7e-09
Identities = 31/63 (49%), Positives = 43/63 (68%)
Frame = +1
Query: 67 LRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 246
L + Q PIP+ ++DE+L++M+ GIC SDVH W G H+V + PMI GHE +G V +
Sbjct: 22 LEIKQLPIPQPNEDELLVKMEYSGICHSDVHTW-LGDF-HYVSKCPMIGGHEGAGSVISV 79
Query: 247 GSK 255
GSK
Sbjct: 80 GSK 82
Score = 36.7 bits (81), Expect = 0.49
Identities = 34/128 (26%), Positives = 57/128 (44%), Gaps = 3/128 (2%)
Frame = +3
Query: 252 EVKNLTVGDRVAIE-PGVPCRYCEFCKTGRYHLCPDMIFCATPPV-TRKPRQILQARSRF 425
+VKN +GD+V I+ C CE+C+TG LCP + T + ++
Sbjct: 82 KVKNWQIGDKVGIKLVQGNCLNCEYCQTGHEPLCPHVWNIGVQKYGTFQEYATIRDVDAI 141
Query: 426 LLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGA-GPIGLLTMLTAKAFGAH 602
+ S + G + ++E V +G +V V GA G +G + A+A G
Sbjct: 142 KIPKSMNMAAAAPVLCGGVT-AYKALKESEVKSGQIVAVTGAGGGLGSFAIQYARAMGM- 199
Query: 603 KVLIIDIL 626
+V+ DI+
Sbjct: 200 RVVAEDIV 207
>UniRef50_A4XHJ7 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Caldicellulosiruptor saccharolyticus DSM
8903|Rep: Alcohol dehydrogenase GroES domain protein -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 324
Score = 62.5 bits (145), Expect = 9e-09
Identities = 45/158 (28%), Positives = 72/158 (45%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A+ Y DLR+ + +P + E+L+++ GICG+DVH + G+ G + P+I+GHE
Sbjct: 4 AVFYGKRDLRVEEFDLPPLKQGEILVKVKACGICGTDVHIF-NGEKGSAKVTPPIILGHE 62
Query: 223 ASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVR 402
G V + +KS + ++ + P G R + +A L+G
Sbjct: 63 FCGEV--VETKSSLFKVGDKVSIDPNIYCGVCRFCRSGKVQLCES-LTALGVNLNGGFAE 119
Query: 403 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
Y D + EE AL EPLA +H K+ E
Sbjct: 120 YAIVPEKQAILFED-IEFEEAALAEPLACCLHGIKKLE 156
Score = 48.4 bits (110), Expect = 1e-04
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 1/128 (0%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATP-PVTRKPRQILQARSRFLLQAS*S 446
VGD+V+I+P + C C FC++G+ LC + I+ + L +
Sbjct: 77 VGDKVSIDPNIYCGVCRFCRSGKVQLCESLTALGVNLNGGFAEYAIVPEKQAILFEDIEF 136
Query: 447 RDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDIL 626
+ G +++ + VL++G GPIGL+ + K +GA+ V +I
Sbjct: 137 EEAALAEPLACCLHGIKKLE---IKPIDKVLIIGLGPIGLIMLEILKLYGAYNVYGYEID 193
Query: 627 QSRLDFAK 650
+ R + AK
Sbjct: 194 EFRKEIAK 201
>UniRef50_Q0UBF8 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 288
Score = 62.5 bits (145), Expect = 9e-09
Identities = 29/73 (39%), Positives = 47/73 (64%), Gaps = 1/73 (1%)
Frame = +1
Query: 37 LTALLYKPND-LRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIM 213
+ AL Y + +VQ +P I DD+VL+++ G+CG+D+HY + G F+ + P+I
Sbjct: 22 MKALQYSEAEKFAVVQIDVPSIGDDDVLVKISACGVCGTDLHYHK----GEFLAKWPLIP 77
Query: 214 GHEASGVVAKIGS 252
GHEA+G +A IG+
Sbjct: 78 GHEAAGTIAAIGA 90
>UniRef50_Q1Q2R9 Cluster: Similar to sorbitol dehydrogenase; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Similar to
sorbitol dehydrogenase - Candidatus Kuenenia
stuttgartiensis
Length = 339
Score = 62.1 bits (144), Expect = 1e-08
Identities = 48/140 (34%), Positives = 62/140 (44%), Gaps = 6/140 (4%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPP-----VTRKPRQILQARS 419
VK VGDRV + VPC C +C G + +C + P R P QI R
Sbjct: 69 VKQFKVGDRVTVAHHVPCNTCHYCLNGHHSVCDTLRTTNFYPGGFAEFLRVP-QINVDRG 127
Query: 420 RFLLQAS*SRDHGRRSATGAPRGGHSRVQE-GGVSAGHVVLVLGAGPIGLLTMLTAKAFG 596
F+L S D G P R Q G +LV+G+G GLL + A+A G
Sbjct: 128 TFILPQEMSYDEG---TFVEPLACSIRGQRLSNFKPGQSLLVIGSGISGLLHIQLARALG 184
Query: 597 AHKVLIIDILQSRLDFAKSL 656
A K+ DI + RL FAK +
Sbjct: 185 AGKIFATDINEYRLKFAKKI 204
Score = 56.8 bits (131), Expect = 4e-07
Identities = 25/69 (36%), Positives = 42/69 (60%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A+ Y ND+R+ + P P+I E+L+++ GICGSDV W + + + P+++GHE
Sbjct: 4 AMYYNNNDVRIEEMPTPQIGPGELLVKIFASGICGSDVMEWYR------IKKAPLVLGHE 57
Query: 223 ASGVVAKIG 249
+G + IG
Sbjct: 58 IAGEIVAIG 66
>UniRef50_Q9RTU4 Cluster: L-threonine 3-dehydrogenase; n=178;
Bacteria|Rep: L-threonine 3-dehydrogenase - Deinococcus
radiodurans
Length = 348
Score = 62.1 bits (144), Expect = 1e-08
Identities = 44/136 (32%), Positives = 61/136 (44%), Gaps = 1/136 (0%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATP-PVTRKPRQILQARSRFL 428
EV+ +GDRV+ E V C +C C+ GR HLC + P + +L A + F
Sbjct: 75 EVRGFEIGDRVSGEGHVTCGHCRNCRAGRRHLCRNTQGVGVNRPGSFAEYLVLPAFNAFK 134
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
L D +A P G G VL+ GAGPIG + A+ GA V
Sbjct: 135 LPDDIPDDV---AAIFDPFGNAVHTALSFDLVGEDVLITGAGPIGCMAAAVARHVGARNV 191
Query: 609 LIIDILQSRLDFAKSL 656
+I D+ RLD A+ +
Sbjct: 192 VITDVNDYRLDLARQM 207
Score = 52.8 bits (121), Expect = 7e-06
Identities = 35/142 (24%), Positives = 62/142 (43%)
Frame = +1
Query: 73 LVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 252
+++T +P +++L+R+ ICG+DVH ++ + PM++GHE GVVA +GS
Sbjct: 15 MIETEVPTPGPNDLLIRIRKGSICGTDVHIYKWDDWASQTVPVPMVVGHEYVGVVAGMGS 74
Query: 253 KSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADFCF 432
+ R ++ G + R + G+ Y A F
Sbjct: 75 EVRGFEIGDRVSGEGHVTCGHCRNCRAGRRHLCRN-TQGVGVNRPGSFAEYLVLPAFNAF 133
Query: 433 KLPDHVTMEEGALLEPLAVGIH 498
KLPD + + A+ +P +H
Sbjct: 134 KLPDDIPDDVAAIFDPFGNAVH 155
>UniRef50_Q81V29 Cluster: Alcohol dehydrogenase, zinc-containing;
n=19; Bacteria|Rep: Alcohol dehydrogenase,
zinc-containing - Bacillus anthracis
Length = 350
Score = 61.7 bits (143), Expect = 2e-08
Identities = 36/127 (28%), Positives = 56/127 (44%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SR 449
VGDRV +EP C CE CK G Y++C ++F + +
Sbjct: 87 VGDRVVVEPIYSCGKCEACKHGHYNVCEQLVFHGLGGEGGGFSEYTVVPEDMVHHIPDEM 146
Query: 450 DHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQ 629
+ + + V++ + G V V G GPIGLL + AKA GA V+ +++ +
Sbjct: 147 TYEQGALVEPAAVAVHAVRQSKLKEGEAVAVFGCGPIGLLVIQAAKAAGATPVIAVELSK 206
Query: 630 SRLDFAK 650
R + AK
Sbjct: 207 ERQELAK 213
Score = 59.3 bits (137), Expect = 8e-08
Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 7/164 (4%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQC-----GHFV--LEEP 204
L + D+R+ + P P + V +++ GICG+D+H + G H + ++ P
Sbjct: 5 LWHNQRDVRVEEVPEPTVKPGAVKIKVKWCGICGTDLHEYLAGPIFIPTEEHPLTHVKAP 64
Query: 205 MIMGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQL 384
+I+GHE SG V +IG ++ P G + +
Sbjct: 65 VILGHEFSGEVVEIGEGVTSHKVGDRVVVEPIYSCGKCEACKHGHYNVCEQLVFHGLGGE 124
Query: 385 HGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
G Y D +PD +T E+GAL+EP AV +HA ++++
Sbjct: 125 GGGFSEYTVVPEDMVHHIPDEMTYEQGALVEPAAVAVHAVRQSK 168
>UniRef50_A1D0R7 Cluster: Alcohol dehydrogenase; n=2;
Trichocomaceae|Rep: Alcohol dehydrogenase - Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 364
Score = 61.7 bits (143), Expect = 2e-08
Identities = 54/175 (30%), Positives = 79/175 (45%), Gaps = 16/175 (9%)
Frame = +1
Query: 37 LTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQC---------GHF 189
L L+ D+RL PIP+ D+V +R+ GICGSD+H +Q G H
Sbjct: 2 LALRLHGRQDIRLDTVPIPDCLSDQVRVRVAYCGICGSDIHEYQAGPILAPQPQETNPHS 61
Query: 190 VLEEPMIMGHEASGVVAKIGSK---SRI*QLVIEWP--*SPACRVGTASSVRQD--DTTY 348
+ P+I+GHE SG V ++G+ RI Q V+ P P + +S + +T
Sbjct: 62 GAKLPVILGHEISGTVVEVGADVEGIRIGQKVVVNPLLADPQIQAEACTSCLRGRFNTCK 121
Query: 349 APT*SSAPRPQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
T P G A +PD+V++ AL EPLAV H +R+
Sbjct: 122 RATYYGINAP--GGGFSGEISVNAANIVPVPDNVSLRAAALAEPLAVACHMIERS 174
Score = 48.8 bits (111), Expect = 1e-04
Identities = 22/52 (42%), Positives = 35/52 (67%)
Frame = +3
Query: 501 VQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
++ G +AG +L+LGAGPIGL ++ ++ GA K+LI ++ R+D AK L
Sbjct: 171 IERSGFAAGDNILILGAGPIGLGLLILLRSKGAKKILISEVSDLRIDQAKRL 222
>UniRef50_Q38ZV8 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=17; Proteobacteria|Rep: Zinc-containing
alcohol dehydrogenase superfamily - Burkholderia sp.
(strain 383) (Burkholderia cepacia (strain ATCC 17760/
NCIB 9086 / R18194))
Length = 373
Score = 61.3 bits (142), Expect = 2e-08
Identities = 45/168 (26%), Positives = 71/168 (42%), Gaps = 8/168 (4%)
Frame = +1
Query: 58 PNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKG------QCGHFVLEE--PMIM 213
P D+RLV+ P + +V + + GICGSD+H + G H + P+ +
Sbjct: 9 PRDVRLVEIDTPRVGPGDVRIAVAYCGICGSDLHEYADGPHAIPVDTPHPLSRRTAPLTL 68
Query: 214 GHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGN 393
GHE G V ++G + P R + R + A G
Sbjct: 69 GHEFCGTVVEVGEGVTALRAGDRVAVEPEYRCSQCAYCRSGSYNLCVSMGFAGL-MGDGG 127
Query: 394 LVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESRRDTWC 537
+ + A +LPD V++E+ A++EP AV +HA +R E R C
Sbjct: 128 MADFAVVPAYMLHRLPDGVSLEQAAVMEPAAVALHALRRGELRLGETC 175
Score = 58.4 bits (135), Expect = 1e-07
Identities = 38/129 (29%), Positives = 57/129 (44%), Gaps = 1/129 (0%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V L GDRVA+EP C C +C++G Y+LC M F + ++L
Sbjct: 83 VTALRAGDRVAVEPEYRCSQCAYCRSGSYNLCVSMGFAGL--MGDGGMADFAVVPAYMLH 140
Query: 435 AS*SRDHGRRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVL 611
++A P ++ G + G V G GPIGLL ++ AK GA ++
Sbjct: 141 RLPDGVSLEQAAVMEPAAVALHALRRGELRLGETCAVFGLGPIGLLLIMLAKLQGATTIV 200
Query: 612 IIDILQSRL 638
+D+ RL
Sbjct: 201 AVDVSPERL 209
>UniRef50_Q12E06 Cluster: Alcohol dehydrogenase GroES-like; n=2;
Bacteria|Rep: Alcohol dehydrogenase GroES-like -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 346
Score = 61.3 bits (142), Expect = 2e-08
Identities = 42/126 (33%), Positives = 59/126 (46%), Gaps = 6/126 (4%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM------IFCATPPVTRKPRQILQAR 416
V GDRV ++P +PCR C +CKTG ++C A R P L A
Sbjct: 73 VTQFKTGDRVCMDPVIPCRACAYCKTGHENVCLHRQAMGYEFDGAFAEYIRIPAIALTAG 132
Query: 417 SRFLLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFG 596
+ F++ A S + + A R GV G V+VLGAGPIGL+ A+ G
Sbjct: 133 NVFMMPAQMSFESAALAEPLACCINGQR--NAGVQVGDTVVVLGAGPIGLMHAALARLSG 190
Query: 597 AHKVLI 614
A +V++
Sbjct: 191 ARQVIV 196
>UniRef50_A1HSQ8 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Thermosinus carboxydivorans Nor1|Rep:
Alcohol dehydrogenase GroES domain protein - Thermosinus
carboxydivorans Nor1
Length = 340
Score = 61.3 bits (142), Expect = 2e-08
Identities = 46/137 (33%), Positives = 70/137 (51%), Gaps = 2/137 (1%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQI-LQARSRFL 428
EVK+L GDRVAI+ C C C++ R+++C ++ I + A +
Sbjct: 72 EVKDLKPGDRVAIDNVFSCGRCYACRSNRHNVCREVKVLGVHIDGVFQEYIKITADKLYK 131
Query: 429 LQAS*SRDHGRRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
L A + +AT P V GV+ VLV GAGPIGL+ + +K GA +
Sbjct: 132 LPADLPWE---MAATVEPYSIAAEAVDRAGVTKDDTVLVCGAGPIGLVILQASKRLGA-R 187
Query: 606 VLIIDILQSRLDFAKSL 656
V ++DI+ SRL+ AK++
Sbjct: 188 VAVMDIVASRLERAKAM 204
Score = 51.2 bits (117), Expect = 2e-05
Identities = 44/159 (27%), Positives = 68/159 (42%), Gaps = 1/159 (0%)
Frame = +1
Query: 55 KPNDLRLVQTPIPEIS-DDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASG 231
KP L + + P+P EV++++ GICGSDVH + GQ + P I+GHEA G
Sbjct: 8 KPGQLTVGERPMPAAPVGGEVVVKIKAAGICGSDVHIFH-GQ--NPFATYPRILGHEAVG 64
Query: 232 VVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYK 411
V + G++ + + G + R + + G Y K
Sbjct: 65 EVYQAGAEVKDLKPGDRVAIDNVFSCGRCYACRSNRHNVCRE-VKVLGVHIDGVFQEYIK 123
Query: 412 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESRRD 528
AD +KLP + E A +EP ++ A RA +D
Sbjct: 124 ITADKLYKLPADLPWEMAATVEPYSIAAEAVDRAGVTKD 162
>UniRef50_A0IRE9 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Serratia proteamaculans 568|Rep: Alcohol dehydrogenase
GroES-like - Serratia proteamaculans 568
Length = 341
Score = 61.3 bits (142), Expect = 2e-08
Identities = 46/164 (28%), Positives = 75/164 (45%)
Frame = +1
Query: 22 MATDNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE 201
MA++ + KP L + PIP EVLL+M +G+CGSD+H + Q +++
Sbjct: 1 MASEMKVLVCIKPGQLSQQRRPIPLPGTGEVLLKMCALGVCGSDIHAFHGRQP---MMQY 57
Query: 202 PMIMGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQ 381
P ++GHE + V G + + Q + P G ++ R+ TT T S
Sbjct: 58 PAVLGHEINAEVVACGQDAALYQPGQQVVVIPYRHCGRCAACRRGRTTCC-TALSVMGIH 116
Query: 382 LHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
G + Y A D + + + AL+EP A+ HA +R+
Sbjct: 117 RTGAMQEYVTVAEDALLAVTG-IPHLQAALIEPYAIAAHAVRRS 159
>UniRef50_A3I7D7 Cluster: Zinc-containing alcohol dehydrogenase,
long-chain; n=1; Bacillus sp. B14905|Rep:
Zinc-containing alcohol dehydrogenase, long-chain -
Bacillus sp. B14905
Length = 339
Score = 60.9 bits (141), Expect = 3e-08
Identities = 38/158 (24%), Positives = 75/158 (47%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A Y D+R+ + +P + + V +++ GICGSD+H + G + ++GHE
Sbjct: 4 AKFYGMKDIRVEEAELPVLKNGMVKVKIAFAGICGSDLHEYVGGA---YAFRTQPVLGHE 60
Query: 223 ASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVR 402
SGVV ++ ++ P G ++ ++ + + S + G
Sbjct: 61 FSGVVVEVAEGVTHTKVGDRVAVEPPIPCGKCANCKRGYSNLCKSGQSYGYT-ISGGFAE 119
Query: 403 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
Y + + LP+ +++E GAL+EP AV +HA ++++
Sbjct: 120 YAVVREENIYHLPEGMSLELGALVEPTAVAVHAVRQSQ 157
Score = 58.8 bits (136), Expect = 1e-07
Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 1/135 (0%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPD-MIFCATPPVTRKPRQILQARSRFLL 431
V + VGDRVA+EP +PC C CK G +LC + T +++ + + L
Sbjct: 72 VTHTKVGDRVAVEPPIPCGKCANCKRGYSNLCKSGQSYGYTISGGFAEYAVVREENIYHL 131
Query: 432 QAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVL 611
S + G A H+ V++ + G + GAGPIGLL + KA GA ++
Sbjct: 132 PEGMSLELGALVEPTAV-AVHA-VRQSQLKLGDTAAIFGAGPIGLLILQAVKAAGASEIF 189
Query: 612 IIDILQSRLDFAKSL 656
++++ R A L
Sbjct: 190 VVEVSDERRQKALEL 204
>UniRef50_A0JVZ1 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Arthrobacter sp. FB24|Rep: Alcohol
dehydrogenase GroES domain protein - Arthrobacter sp.
(strain FB24)
Length = 344
Score = 60.5 bits (140), Expect = 3e-08
Identities = 44/135 (32%), Positives = 64/135 (47%), Gaps = 1/135 (0%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVTRKPRQILQARSRFLL 431
V + +VGDRVAI+ C CE C+ G C + ++ P + + I+ A+ +L
Sbjct: 83 VTHPSVGDRVAIQHYSGCGTCETCRKGWDVHCENARVYSLNRPGGCQDQVIVTAKDAVVL 142
Query: 432 QAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVL 611
S S G A GA + +Q V G VLV+GAGP+GL + A+A G H +
Sbjct: 143 PDSVSFATGAFLACGATTA-YQAIQRSEVRPGGTVLVIGAGPVGLAVLTWARALGLH-AI 200
Query: 612 IIDILQSRLDFAKSL 656
D R FA +
Sbjct: 201 ATDPSPQRRKFASKI 215
Score = 46.4 bits (105), Expect = 6e-04
Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 5/79 (6%)
Frame = +1
Query: 28 TDNLTALLYKPND-LRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP 204
T + AL + D + +V +PE E++L + G+CGSD+HY+ +P
Sbjct: 2 TTTVRALRFAEKDRVSVVDAALPEAGPGEIVLDVKAAGLCGSDLHYFHMTHNQMQNATQP 61
Query: 205 ----MIMGHEASGVVAKIG 249
M GHE +GVVA IG
Sbjct: 62 RSPEMTPGHEIAGVVASIG 80
>UniRef50_Q927H5 Cluster: Lin2813 protein; n=16; Firmicutes|Rep:
Lin2813 protein - Listeria innocua
Length = 350
Score = 60.1 bits (139), Expect = 5e-08
Identities = 53/165 (32%), Positives = 71/165 (43%), Gaps = 5/165 (3%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A+LY+ N ++ Q D+V + + VGICGSD+H Q + P +MGHE
Sbjct: 4 AVLYENNVIKAEQIDEATCGKDQVRVEVKAVGICGSDIHKMQT----RWKYPLPAVMGHE 59
Query: 223 ASGVVAKIGSK---SRI*QLVIEWP*SPA--CRVGTASSVRQDDTTYAPT*SSAPRPQLH 387
+GVV +IGS+ I V P P C A D Y S H
Sbjct: 60 FAGVVTEIGSEVTNVAIGDRVAGIPLEPCMECNYCKAGDFALCD-NYRMVGS-----HFH 113
Query: 388 GNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESR 522
G AD + D + EEGA++EPLAV +H E R
Sbjct: 114 GGFAENVVMKADNVISIGD-LDFEEGAMIEPLAVSMHGVLGIEPR 157
Score = 43.6 bits (98), Expect = 0.004
Identities = 32/134 (23%), Positives = 52/134 (38%), Gaps = 1/134 (0%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLL 431
EV N+ +GDRVA P PC C +CK G + LC + + ++ +
Sbjct: 70 EVTNVAIGDRVAGIPLEPCMECNYCKAGDFALCDNYRMVGSHFHGGFAENVVMKADNVIS 129
Query: 432 QAS*SRDHGRR-SATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
+ G G ++ G V+V G G IG+L + G +
Sbjct: 130 IGDLDFEEGAMIEPLAVSMHGVLGIEP---RLGDTVIVFGIGTIGILVVQCLLLAGVKDI 186
Query: 609 LIIDILQSRLDFAK 650
+ +DI +L A+
Sbjct: 187 IAVDISDKKLADAR 200
>UniRef50_Q5WC08 Cluster: Galactitol-1-phosphate 5-dehydrogenase;
n=1; Bacillus clausii KSM-K16|Rep:
Galactitol-1-phosphate 5-dehydrogenase - Bacillus
clausii (strain KSM-K16)
Length = 352
Score = 60.1 bits (139), Expect = 5e-08
Identities = 43/148 (29%), Positives = 73/148 (49%), Gaps = 3/148 (2%)
Frame = +1
Query: 76 VQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS- 252
++TP+P+ +DE L+++ GICGSD+ + G+ ++ P+++GHE SG V +G+
Sbjct: 17 IETPVPK--EDEALIKVAYCGICGSDLARYFDGKVHNY----PIVLGHEFSGTVEAVGAS 70
Query: 253 --KSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADF 426
+ V+ P P Q + + S + +G + Y A+
Sbjct: 71 VDSVAVGDRVVVAPLLP----NKDDPFMQKGSPALSSSYSFLGSRENGAMAEYVVVKAEN 126
Query: 427 CFKLPDHVTMEEGALLEPLAVGIHACKR 510
LP+ VT+ E AL+EPL V IH +R
Sbjct: 127 LLVLPETVTLAEAALIEPLTVAIHGIER 154
Score = 48.4 bits (110), Expect = 1e-04
Identities = 42/137 (30%), Positives = 64/137 (46%), Gaps = 3/137 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQIL-QARSRFLL 431
V ++ VGDRV + P +P + F + G L F + ++ +A + +L
Sbjct: 71 VDSVAVGDRVVVAPLLPNKDDPFMQKGSPALSSSYSFLGSRENGAMAEYVVVKAENLLVL 130
Query: 432 QAS*SRDHGR--RSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
+ + T A G ++ + AG V VLGAG IG++T+L KA GA K
Sbjct: 131 PETVTLAEAALIEPLTVAIHG----IERIVLPAGEHVCVLGAGTIGIMTILALKARGAGK 186
Query: 606 VLIIDILQSRLDFAKSL 656
V IDI +L FAK +
Sbjct: 187 VTAIDINDEKLAFAKKI 203
>UniRef50_A5ZM46 Cluster: Putative uncharacterized protein; n=2;
Ruminococcus|Rep: Putative uncharacterized protein -
Ruminococcus obeum ATCC 29174
Length = 350
Score = 60.1 bits (139), Expect = 5e-08
Identities = 41/137 (29%), Positives = 62/137 (45%), Gaps = 3/137 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT-PPVTRKPRQILQARSRFLL 431
V + VGDRV+ P +PC C+ C+ G + LC F + + ++ ++
Sbjct: 71 VTKVKVGDRVSGAPLLPCMKCDDCQKGNFSLCKHYSFIGSRQQGSNADYVVVPEQNAVPF 130
Query: 432 QAS*SRDHGR--RSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
+ + G AT A G V + G V +LG G +G+ TM K FG+ K
Sbjct: 131 DKTVPYEQGAMFEPATVAIHG----VFQNDYHGGEYVAILGGGTVGMFTMQWTKIFGSKK 186
Query: 606 VLIIDILQSRLDFAKSL 656
V++ DI RL AK L
Sbjct: 187 VVVFDISDERLALAKRL 203
Score = 37.9 bits (84), Expect = 0.21
Identities = 37/155 (23%), Positives = 66/155 (42%), Gaps = 3/155 (1%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A++ D++ + P+++ V +++ GICGSD+ H V P+++GHE
Sbjct: 4 AVVVANEDVQYQEVEEPKVTKGTVKIKVRYSGICGSDI----PRVLNHGVHFYPIVLGHE 59
Query: 223 ASGVVAKIG---SKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGN 393
SG V ++G +K ++ V P P + + S +
Sbjct: 60 FSGDVVEVGEGVTKVKVGDRVSGAPLLPCMKCDDCQKGNFSLCKHYSFIGSRQQGSNADY 119
Query: 394 LVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIH 498
+V ++A F +P E+GA+ EP V IH
Sbjct: 120 VVVPEQNAVPFDKTVP----YEQGAMFEPATVAIH 150
>UniRef50_A1RYE2 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Thermofilum pendens Hrk 5|Rep: Alcohol
dehydrogenase GroES domain protein - Thermofilum pendens
(strain Hrk 5)
Length = 398
Score = 60.1 bits (139), Expect = 5e-08
Identities = 26/60 (43%), Positives = 40/60 (66%), Gaps = 4/60 (6%)
Frame = +1
Query: 85 PIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHF----VLEEPMIMGHEASGVVAKIGS 252
P+PE DE+L+R+ VGICGSD+H+ + G+ + P+++GHE SGVV K+G+
Sbjct: 47 PVPEPKPDEILIRVKAVGICGSDIHFLETDSEGYILYPGLTRFPVVIGHEFSGVVEKVGT 106
Score = 44.4 bits (100), Expect = 0.002
Identities = 22/49 (44%), Positives = 29/49 (59%)
Frame = +3
Query: 510 GGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
GG G V V GAGPIGL + AKA GA KV+ ++ +R + AK +
Sbjct: 210 GGFKPGAYVAVWGAGPIGLAAIALAKAAGAGKVIAFEVSPTRRELAKKV 258
>UniRef50_Q57517 Cluster: Uncharacterized zinc-type alcohol
dehydrogenase-like protein HI0053; n=18;
Gammaproteobacteria|Rep: Uncharacterized zinc-type
alcohol dehydrogenase-like protein HI0053 - Haemophilus
influenzae
Length = 342
Score = 60.1 bits (139), Expect = 5e-08
Identities = 45/158 (28%), Positives = 79/158 (50%), Gaps = 4/158 (2%)
Frame = +1
Query: 49 LYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 228
L KPN++ + + P PE SD++VL++++ +GICGSD+ + +G + ++ P I+GHE
Sbjct: 10 LEKPNNVVVKEVPYPEKSDNDVLIQVESMGICGSDIGAY-RGT--NPLVTYPRILGHEIV 66
Query: 229 GVVAKIG----SKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNL 396
G V + G R+ VI P C S+ + + + + G +
Sbjct: 67 GRVIESGIGMSDGVRVGDRVIVDP-YVCCGQCYPCSIGRTNCCES---LKVIGVHIDGGM 122
Query: 397 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKR 510
+H A K+PD++ + + L EPL + +HA R
Sbjct: 123 QEVIRHPAHLLTKVPDNLPIHQLPLAEPLTIALHALHR 160
Score = 56.8 bits (131), Expect = 4e-07
Identities = 38/130 (29%), Positives = 66/130 (50%), Gaps = 1/130 (0%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SR 449
VGDRV ++P V C C C GR + C + + +++++ + L + +
Sbjct: 82 VGDRVIVDPYVCCGQCYPCSIGRTNCCESLKVIGVH-IDGGMQEVIRHPAHLLTKVPDNL 140
Query: 450 D-HGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDIL 626
H A H+ + + +G ++++GAG IGL+ L A +GA +L +DIL
Sbjct: 141 PIHQLPLAEPLTIALHA-LHRTTLKSGEHIVIIGAGAIGLMAALAAVQYGAIPIL-VDIL 198
Query: 627 QSRLDFAKSL 656
+ RL++AKSL
Sbjct: 199 EQRLEYAKSL 208
>UniRef50_O58389 Cluster: Probable L-threonine 3-dehydrogenase; n=7;
cellular organisms|Rep: Probable L-threonine
3-dehydrogenase - Pyrococcus horikoshii
Length = 348
Score = 60.1 bits (139), Expect = 5e-08
Identities = 39/135 (28%), Positives = 66/135 (48%), Gaps = 1/135 (0%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVTRKPRQILQARSRFLL 431
V+ + VGD V++E + C C C+ G+YH+C + IF ++ A++ +
Sbjct: 80 VEGIEVGDYVSVETHIVCGKCYACRRGQYHVCQNTKIFGVDTDGVFAEYAVVPAQNIWKN 139
Query: 432 QAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVL 611
S ++ + P G G +G VL+ GAGP+GLL + AKA GA+ V+
Sbjct: 140 PKSIPPEY---ATLQEPLGNAVDTVLAGPISGKSVLITGAGPLGLLGIAVAKASGAYPVI 196
Query: 612 IIDILQSRLDFAKSL 656
+ + R + AK +
Sbjct: 197 VSEPSDFRRELAKKV 211
Score = 50.8 bits (116), Expect = 3e-05
Identities = 21/59 (35%), Positives = 36/59 (61%)
Frame = +1
Query: 73 LVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIG 249
LV+ +P+ EVL+++ ICG+D+H ++ + ++ P IMGHE +G V +IG
Sbjct: 19 LVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEIG 77
>UniRef50_Q65L05 Cluster: YjmD; n=1; Bacillus licheniformis ATCC
14580|Rep: YjmD - Bacillus licheniformis (strain DSM 13
/ ATCC 14580)
Length = 338
Score = 59.7 bits (138), Expect = 6e-08
Identities = 44/162 (27%), Positives = 72/162 (44%), Gaps = 4/162 (2%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A++ KP + P PE + EVL+++ GICGSDVH++ + + P I GHE
Sbjct: 4 AVMTKPYSIEFHDIPRPEPASGEVLVKIKAAGICGSDVHFYDG---SNPYAQYPQIFGHE 60
Query: 223 ASGVVAKIGS----KSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHG 390
+G++ K G+ +S ++VIE PA G R+ T + G
Sbjct: 61 LAGIIEKTGAGVRGRSAGERVVIE----PAIPCGGCYPCRKGRTNACMNIDMIGSVR-RG 115
Query: 391 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
+ +P+ + AL EP ++G A +RA+
Sbjct: 116 GFADFIIVPETHVHPIPEQMDFATAALCEPFSIGAQAVRRAD 157
Score = 50.8 bits (116), Expect = 3e-05
Identities = 33/134 (24%), Positives = 59/134 (44%), Gaps = 1/134 (0%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKP-RQILQARSRFLL 431
V+ + G+RV IEP +PC C C+ GR + C ++ + V R + +
Sbjct: 72 VRGRSAGERVVIEPAIPCGGCYPCRKGRTNACMNIDMIGS--VRRGGFADFIIVPETHVH 129
Query: 432 QAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVL 611
D + G V+ + G +++LG GPIGL + K +V+
Sbjct: 130 PIPEQMDFATAALCEPFSIGAQAVRRADIQTGETIVILGMGPIGLTILAQVKKRFDVRVI 189
Query: 612 IIDILQSRLDFAKS 653
+D ++ RL+ A++
Sbjct: 190 AVDPVRERLELAEA 203
>UniRef50_Q5V6V7 Cluster: Zinc-binding dehydrogenase; n=1;
Haloarcula marismortui|Rep: Zinc-binding dehydrogenase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 344
Score = 59.7 bits (138), Expect = 6e-08
Identities = 41/138 (29%), Positives = 60/138 (43%), Gaps = 3/138 (2%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQ-ARSRFL 428
+V VGDRVAI P VPC C +CK G HLC + T + R +
Sbjct: 70 DVDRFAVGDRVAINPTVPCNACSYCKKGETHLCENNTSIGGAGDTILDGAFAEYVRVPAI 129
Query: 429 LQAS*SRDHGRRSATGAPRG--GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAH 602
R+A P H V++ + G V ++GAGPIGLL + + GA
Sbjct: 130 NVEDIGEMSFERAALAEPLACCVHG-VEQADIKPGDSVGIIGAGPIGLLLLQAFRNAGAA 188
Query: 603 KVLIIDILQSRLDFAKSL 656
+++ ++ R + A L
Sbjct: 189 PIVVSELDDERRELAADL 206
Score = 52.8 bits (121), Expect = 7e-06
Identities = 38/145 (26%), Positives = 68/145 (46%), Gaps = 3/145 (2%)
Frame = +1
Query: 91 PEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKSRI*Q 270
P+ +DDEVL+++ +C +D H + G F E P+++GHE +G VA++G+
Sbjct: 20 PDPADDEVLVQVGACSVCMTDYHMYH----GTFAAETPLVLGHEGAGTVAEVGADVDRFA 75
Query: 271 LVIEWP*SPACRVGTASSVRQDDTTYAPT*SS---APRPQLHGNLVRYYKHAADFCFKLP 441
+ +P S ++ +T +S A L G Y + A +
Sbjct: 76 VGDRVAINPTVPCNACSYCKKGETHLCENNTSIGGAGDTILDGAFAEYVRVPAINVEDIG 135
Query: 442 DHVTMEEGALLEPLAVGIHACKRAE 516
+ ++ E AL EPLA +H ++A+
Sbjct: 136 E-MSFERAALAEPLACCVHGVEQAD 159
>UniRef50_Q025V7 Cluster: Alcohol dehydrogenase GroES domain
protein; n=2; Bacteria|Rep: Alcohol dehydrogenase GroES
domain protein - Solibacter usitatus (strain Ellin6076)
Length = 339
Score = 59.3 bits (137), Expect = 8e-08
Identities = 43/129 (33%), Positives = 60/129 (46%), Gaps = 1/129 (0%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCA-TPPVTRKPRQILQARSRFLLQAS*SR 449
GDRV + P PC C C+ G H+C ++ F P + + A + L S S
Sbjct: 79 GDRVTVRPLDPCGTCPACRMGHSHICHNLKFIGIDTPGALQGMWTVPAHTLHRLPDSLSL 138
Query: 450 DHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQ 629
G A R+ E + AG +V+G GPIG+L L AKA GA +VL ++
Sbjct: 139 REGAMVEPIAVACHDVRMSE--LQAGEFAVVIGGGPIGILIALVAKARGA-RVLQAEVNP 195
Query: 630 SRLDFAKSL 656
RL A+ L
Sbjct: 196 FRLQLARDL 204
Score = 52.0 bits (119), Expect = 1e-05
Identities = 37/136 (27%), Positives = 59/136 (43%)
Frame = +1
Query: 109 EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKSRI*QLVIEWP 288
+V + ++ GICG+D+H + L P +MGHE SG +A +G Q
Sbjct: 26 QVQINVEFCGICGTDLHLFHGAMAHRLTL--PHVMGHEMSGTLAAVGEGVAGWQAGDRVT 83
Query: 289 *SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADFCFKLPDHVTMEEGA 468
P GT + R + G L + A +LPD +++ EGA
Sbjct: 84 VRPLDPCGTCPACRMGHSHICHN-LKFIGIDTPGALQGMWTVPAHTLHRLPDSLSLREGA 142
Query: 469 LLEPLAVGIHACKRAE 516
++EP+AV H + +E
Sbjct: 143 MVEPIAVACHDVRMSE 158
>UniRef50_A0UVK1 Cluster: Alcohol dehydrogenase, zinc-binding; n=1;
Clostridium cellulolyticum H10|Rep: Alcohol
dehydrogenase, zinc-binding - Clostridium cellulolyticum
H10
Length = 302
Score = 59.3 bits (137), Expect = 8e-08
Identities = 42/137 (30%), Positives = 59/137 (43%), Gaps = 2/137 (1%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPR--QILQARSRF 425
+V +G RVA +P + C C+ CK R + C DM VTR Q L R
Sbjct: 36 KVTKFKIGQRVAADPNIFCETCDACKENRQNFCSDMEVVG---VTRHGAFAQYLTVPERC 92
Query: 426 LLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
+ S S ++ G+ G VL+ GAGPIGL+ A GA
Sbjct: 93 VFDVS-GLTFTEASMVEPLACVVYGQEKAGIPLGASVLIFGAGPIGLMHSQLAAINGAAS 151
Query: 606 VLIIDILQSRLDFAKSL 656
V ++D+ + +L AK L
Sbjct: 152 VTVVDLFEDKLALAKKL 168
>UniRef50_Q9RS48 Cluster: Alcohol dehydrogenase, zinc-containing;
n=36; Bacteria|Rep: Alcohol dehydrogenase,
zinc-containing - Deinococcus radiodurans
Length = 431
Score = 58.8 bits (136), Expect = 1e-07
Identities = 45/149 (30%), Positives = 66/149 (44%), Gaps = 16/149 (10%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLC----PDMIFCATP----PVTRKPRQIL 407
EV+N GDRV I C YC C+ G C P+ T P + P +
Sbjct: 98 EVRNFVPGDRVVIPSSASCGYCPPCREGNTSQCDNANPNGPSAGTAFYGGPKSSGPLNGM 157
Query: 408 QARSRFLLQAS*S--------RDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIG 563
QA ++ A+ S D + + + GV G VV+VLG GP+G
Sbjct: 158 QAEKVRVVYANSSLVKLPDNVSDDQAIMISDIFPTAYFGAEIAGVKTGSVVVVLGCGPVG 217
Query: 564 LLTMLTAKAFGAHKVLIIDILQSRLDFAK 650
++++AK GA +V+ +D L RLD A+
Sbjct: 218 QFSIISAKLLGATRVIAVDRLDDRLDMAR 246
Score = 39.9 bits (89), Expect = 0.053
Identities = 22/67 (32%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Frame = +1
Query: 64 DLRLVQTPIPEI-SDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 240
D+RL P P+I + + ++R+ ICG+D+H+ +G V I+GHE G+V
Sbjct: 37 DIRLDDVPEPKIEAPTDAIVRLTASAICGTDLHF-IRGTMSDMV--PGTILGHEGVGIVE 93
Query: 241 KIGSKSR 261
+G + R
Sbjct: 94 AVGPEVR 100
>UniRef50_Q65L02 Cluster: Putative uncharacterized protein; n=1;
Bacillus licheniformis ATCC 14580|Rep: Putative
uncharacterized protein - Bacillus licheniformis (strain
DSM 13 / ATCC 14580)
Length = 337
Score = 58.8 bits (136), Expect = 1e-07
Identities = 41/158 (25%), Positives = 69/158 (43%), Gaps = 1/158 (0%)
Frame = +1
Query: 55 KPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHF-VLEEPMIMGHEASG 231
KP ++ +PE+ D E L+R+ +GICG+D H + CG P ++GHE SG
Sbjct: 8 KPYRFKMTDVKMPELKDGEALVRIKRIGICGTDFHAY----CGRQPFFSYPRVLGHELSG 63
Query: 232 VVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYK 411
+ I + + + P G + R + G + Y
Sbjct: 64 EIVSIDNSGGTLKPGDQVSIIPYLECGACIACRNGRPNCCVN-LNVLGVHTDGGMREYIN 122
Query: 412 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESRR 525
AD K + +T+ E A++E L++G HA +RA ++
Sbjct: 123 VPADHLLK-TEGLTLSEAAVVECLSIGAHAAERANIKK 159
Score = 54.8 bits (126), Expect = 2e-06
Identities = 39/129 (30%), Positives = 60/129 (46%)
Frame = +3
Query: 264 LTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS* 443
L GD+V+I P + C C C+ GR + C ++ R+ + + LL+
Sbjct: 75 LKPGDQVSIIPYLECGACIACRNGRPNCCVNLNVLGVH-TDGGMREYINVPADHLLKTEG 133
Query: 444 SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDI 623
G H+ + + G VLV+GAGPIGL M AK GA KV+ +D+
Sbjct: 134 LTLSEAAVVECLSIGAHA-AERANIKKGETVLVVGAGPIGLSVMKFAKLKGA-KVIAMDV 191
Query: 624 LQSRLDFAK 650
+ RL F++
Sbjct: 192 RKERLTFSR 200
>UniRef50_Q1PUQ4 Cluster: Similar to zinc-containing dehydrogenase;
n=1; Candidatus Kuenenia stuttgartiensis|Rep: Similar to
zinc-containing dehydrogenase - Candidatus Kuenenia
stuttgartiensis
Length = 386
Score = 58.8 bits (136), Expect = 1e-07
Identities = 27/80 (33%), Positives = 45/80 (56%), Gaps = 4/80 (5%)
Frame = +1
Query: 34 NLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHF----VLEE 201
N+ + +++ + +P + DDE+L+R+ GICGSD H ++ + G+ V E
Sbjct: 29 NVGSQVWQHTQFEVKDVSVPNLQDDEILVRIKSCGICGSDTHLYETDKDGYIIFSGVTEL 88
Query: 202 PMIMGHEASGVVAKIGSKSR 261
P I+GHE SG+V + G R
Sbjct: 89 PRIIGHELSGIVEQTGKNVR 108
Score = 40.7 bits (91), Expect = 0.030
Identities = 19/46 (41%), Positives = 26/46 (56%)
Frame = +3
Query: 510 GGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFA 647
GG G V+V G GPIGL + AK GA +++ DI+ R + A
Sbjct: 200 GGFQPGATVVVYGTGPIGLGAIALAKIAGASQIIAFDIIDERANIA 245
>UniRef50_Q9K5Y6 Cluster: L-iditol 2-dehydrogenase; n=8;
Bacteria|Rep: L-iditol 2-dehydrogenase - Bacillus
halodurans
Length = 348
Score = 58.4 bits (135), Expect = 1e-07
Identities = 43/159 (27%), Positives = 70/159 (44%), Gaps = 8/159 (5%)
Frame = +1
Query: 64 DLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKG------QCGHFVLEE--PMIMGH 219
D+R+ P +V +++ GICGSD+H + G H + EE P++MGH
Sbjct: 11 DVRVDDIAEPATLKGKVKIKVKWCGICGSDLHEYAAGPIFIPQNSPHSLTEEKAPIVMGH 70
Query: 220 EASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLV 399
E SG V ++G + P GT ++ +Q G
Sbjct: 71 EFSGQVVEVGDGVTKCEEGDRVVVEPIFACGTCTACKQGKYNLCEQLGFLGLAGGGGGFS 130
Query: 400 RYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
Y K+PD V+ E+GAL+EP AV ++A ++++
Sbjct: 131 EYVTVDEHMVHKIPDTVSFEQGALVEPAAVALYAVRQSQ 169
Score = 52.8 bits (121), Expect = 7e-06
Identities = 33/128 (25%), Positives = 54/128 (42%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SRD 452
GDRV +EP C C CK G+Y+LC + F + + + + +
Sbjct: 89 GDRVVVEPIFACGTCTACKQGKYNLCEQLGFLGLAGGGGGFSEYVTVDEHMVHKIPDTVS 148
Query: 453 HGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQS 632
+ + V++ + G +V G GPIGLL + KA GA K+ +++
Sbjct: 149 FEQGALVEPAAVALYAVRQSQFNVGDQAVVFGTGPIGLLVIEALKASGASKIYAVELSTE 208
Query: 633 RLDFAKSL 656
R A+ L
Sbjct: 209 RRQRAEQL 216
>UniRef50_Q8ELI9 Cluster: Sorbitol dehydrogenase; n=2;
Bacillaceae|Rep: Sorbitol dehydrogenase - Oceanobacillus
iheyensis
Length = 326
Score = 58.4 bits (135), Expect = 1e-07
Identities = 45/146 (30%), Positives = 66/146 (45%)
Frame = +1
Query: 94 EISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKSRI*QL 273
++SDDEV +R+ GICGSD+ + KG+ H P++ GHE G V + G KS
Sbjct: 22 KLSDDEVRIRLIYGGICGSDISVF-KGKLPH--ANYPVVPGHELIGTVIETG-KSAADFA 77
Query: 274 VIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADFCFKLPDHVT 453
P G + T T + G + +A + LPD +T
Sbjct: 78 GKRVAIMPNSFCGKCEYCKVGKTNIC-TEKQSLGINRDGGFAEEFVISAKYVLSLPDQLT 136
Query: 454 MEEGALLEPLAVGIHACKRAESRRDT 531
E+ L+EPLAV +HA K+ +T
Sbjct: 137 NEKAVLIEPLAVIVHAMKKVVITEET 162
Score = 34.7 bits (76), Expect = 2.0
Identities = 13/28 (46%), Positives = 18/28 (64%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPD 356
G RVAI P C CE+CK G+ ++C +
Sbjct: 78 GKRVAIMPNSFCGKCEYCKVGKTNICTE 105
>UniRef50_Q1ARQ8 Cluster: Alcohol dehydrogenase GroES-like protein
precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep:
Alcohol dehydrogenase GroES-like protein precursor -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 341
Score = 58.4 bits (135), Expect = 1e-07
Identities = 45/150 (30%), Positives = 64/150 (42%), Gaps = 2/150 (1%)
Frame = +1
Query: 58 PNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVV 237
P ++ + + P PE V+LR GICGS+V + G+ G+ P++MGHE SG V
Sbjct: 9 PREMAVEEIPEPEAGPGAVVLRTGAAGICGSEVEGY-LGRMGN--RTPPLVMGHEFSGTV 65
Query: 238 AKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*S--SAPRPQLHGNLVRYYK 411
+G + +P G R P + RP G Y +
Sbjct: 66 VAVGEGVDEAWVGRRVAVNPLISCGECRLCRSGHENICPERALIGIHRP---GAFAEYVE 122
Query: 412 HAADFCFKLPDHVTMEEGALLEPLAVGIHA 501
A LP+ V + AL EPLA G+HA
Sbjct: 123 VPAGSLHALPEGVDLRSAALAEPLANGVHA 152
Score = 38.3 bits (85), Expect = 0.16
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 4/121 (3%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPD--MIFCATPPVTRKPRQILQARSRFLLQAS* 443
VG RVA+ P + C C C++G ++CP+ +I P + ++ A S L A
Sbjct: 77 VGRRVAVNPLISCGECRLCRSGHENICPERALIGIHRPGAFAEYVEV-PAGS---LHALP 132
Query: 444 SRDHGRRSATGAPRGGHSRVQEGGVSAG--HVVLVLGAGPIGLLTMLTAKAFGAHKVLII 617
R +A P G+ G + +V+GAG IGL+ + A G +V +
Sbjct: 133 EGVDLRSAALAEPLANGVHAAGLGLERGPAELAVVVGAGTIGLMCLQAAVLSGIPEVWAV 192
Query: 618 D 620
+
Sbjct: 193 E 193
>UniRef50_A0NKD6 Cluster: Zc-binding dehydrogenase; n=3; Oenococcus
oeni|Rep: Zc-binding dehydrogenase - Oenococcus oeni
ATCC BAA-1163
Length = 385
Score = 58.4 bits (135), Expect = 1e-07
Identities = 46/168 (27%), Positives = 73/168 (43%), Gaps = 12/168 (7%)
Frame = +1
Query: 34 NLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQ----CGHFVLEE 201
++ +LY P D+RL + IP+ D+V + + GICGSD+H + G H + E
Sbjct: 27 SIAQVLYGPKDMRLEKVDIPDPGKDQVQISVYFNGICGSDIHEYLDGMDLATVEHPITHE 86
Query: 202 --PMIMGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPR 375
P+I GHE +G V K G+ + ++ P G ++ R +
Sbjct: 87 KAPLISGHEFAGKVKKTGALVKGLKVGDHVTVEPIIACGYCAACRSGNYNLCENSIGEDN 146
Query: 376 P------QLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHA 501
+G L + + + KLPD + + GAL EP AV A
Sbjct: 147 AAGFLGFSANGGLSQLCNVSYIYAHKLPDDLPLSLGALCEPTAVAAQA 194
Score = 53.2 bits (122), Expect = 5e-06
Identities = 26/47 (55%), Positives = 32/47 (68%)
Frame = +3
Query: 516 VSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
+ AG VL+ GAGPIGLLT + AK GAH V+I D+ SRL A+ L
Sbjct: 200 IHAGDDVLISGAGPIGLLTAILAKISGAHDVMISDVSTSRLQIAEKL 246
Score = 47.2 bits (107), Expect = 3e-04
Identities = 18/36 (50%), Positives = 24/36 (66%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMI 362
VK L VGD V +EP + C YC C++G Y+LC + I
Sbjct: 107 VKGLKVGDHVTVEPIIACGYCAACRSGNYNLCENSI 142
>UniRef50_Q3A2I8 Cluster: Putative zinc-containing alcohol
dehydrogenase; n=1; Pelobacter carbinolicus DSM
2380|Rep: Putative zinc-containing alcohol dehydrogenase
- Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 327
Score = 58.0 bits (134), Expect = 2e-07
Identities = 42/162 (25%), Positives = 64/162 (39%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A L +P + + +TPIP EVL+R G+CGSD + G F + P+I GHE
Sbjct: 4 AQLVEPGKITIQETPIPSPKPGEVLIRTSVAGLCGSDHSVYH----GKFDVPLPVIPGHE 59
Query: 223 ASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVR 402
A G + ++G + P G + P+ +G L
Sbjct: 60 AIGTIVELGEGVTNVSVGQRVTIQPNFGCGVCPLCKSGHDNICPS-KIRLGIDTNGVLAE 118
Query: 403 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESRRD 528
Y + + + LP + E EPLAV +H +D
Sbjct: 119 YVTAPSRYVWALPADLPDEVAVFTEPLAVAVHGVNMLPPNKD 160
Score = 53.2 bits (122), Expect = 5e-06
Identities = 40/134 (29%), Positives = 60/134 (44%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V N++VG RV I+P C C CK+G ++CP I + + A SR++
Sbjct: 71 VTNVSVGQRVTIQPNFGCGVCPLCKSGHDNICPSKIRLGI-DTNGVLAEYVTAPSRYVWA 129
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
T V + VLV+GAG +GLL + A+ GA ++
Sbjct: 130 LPADLPDEVAVFTEPLAVAVHGVNMLPPNKDDRVLVMGAGIVGLLALQVARISGA-EITA 188
Query: 615 IDILQSRLDFAKSL 656
D+ Q+RLD A+ L
Sbjct: 189 CDLEQTRLDLAEKL 202
>UniRef50_A6VRA2 Cluster: Alcohol dehydrogenase GroES domain
protein; n=2; Oceanospirillales|Rep: Alcohol
dehydrogenase GroES domain protein - Marinomonas sp.
MWYL1
Length = 340
Score = 58.0 bits (134), Expect = 2e-07
Identities = 47/152 (30%), Positives = 66/152 (43%)
Frame = +1
Query: 61 NDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 240
ND L+ T P EVL++ GICGSD+H GQ FV + P I GHE SGVVA
Sbjct: 10 NDYALIDTLQPVAEAGEVLIKTAFAGICGSDLHIIH-GQ-NPFV-QFPRITGHEFSGVVA 66
Query: 241 KIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAA 420
+G ++ + P G + R +G + A
Sbjct: 67 AVGEGVTHVKIGDKVCVDPVISCGECYACRAGRFNVCAK-LQVFGVHRNGGFGEFTSAPA 125
Query: 421 DFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
LPD+VT+E+ AL+EP ++ + R E
Sbjct: 126 SNVLVLPDNVTLEQAALVEPYSIATNVLSRME 157
Score = 54.0 bits (124), Expect = 3e-06
Identities = 38/136 (27%), Positives = 67/136 (49%), Gaps = 2/136 (1%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVTRKPRQILQARSRFLL 431
V ++ +GD+V ++P + C C C+ GR+++C + +F A + +L
Sbjct: 72 VTHVKIGDKVCVDPVISCGECYACRAGRFNVCAKLQVFGVHRNGGFGEFTSAPASNVLVL 131
Query: 432 QAS*SRDHGRRSATGAPRGGHSRV-QEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
+ + + ++A P + V G +LV GAG IGL + AKA G ++
Sbjct: 132 PDNVTLE---QAALVEPYSIATNVLSRMEPIPGDTLLVYGAGVIGLTIVQVAKAMGIERI 188
Query: 609 LIIDILQSRLDFAKSL 656
++ DI+ RL+ AKSL
Sbjct: 189 IVTDIVDERLETAKSL 204
>UniRef50_A4J9K3 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Desulfotomaculum reducens MI-1|Rep:
Alcohol dehydrogenase GroES domain protein -
Desulfotomaculum reducens MI-1
Length = 345
Score = 58.0 bits (134), Expect = 2e-07
Identities = 38/132 (28%), Positives = 60/132 (45%), Gaps = 4/132 (3%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQIL-QARSRFLL 431
V + G+RV + PG+PC C C TG HLCP++ +L ++
Sbjct: 72 VTEVHCGERVQVSPGLPCGVCPNCLTGLNHLCPNIEIMGFHYDGGFAEYVLIPSKGVKAK 131
Query: 432 QAS*SRDHG--RRSATGAPRGGHSRVQEG-GVSAGHVVLVLGAGPIGLLTMLTAKAFGAH 602
+ DH +A P +QE + +G +++ GAGP+G+L AK GA
Sbjct: 132 VLNKLPDHFPIELAALTEPLACCINIQESMDIGSGDTIIIFGAGPVGILNAKLAKLRGAK 191
Query: 603 KVLIIDILQSRL 638
+ I D+ + RL
Sbjct: 192 NIAIFDVNKKRL 203
Score = 46.8 bits (106), Expect = 5e-04
Identities = 46/156 (29%), Positives = 62/156 (39%), Gaps = 5/156 (3%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 225
LL + N+L L IP EVL+++ GIC +D+ + + GH L P I+GHE
Sbjct: 5 LLEQANNLVLKTIEIPRCKAGEVLVKVAACGICRTDMKSY---RLGHRDLHLPRILGHEI 61
Query: 226 SGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRY 405
+G V +IG+ SP G + P G Y
Sbjct: 62 AGTVVEIGAGVTEVHCGERVQVSPGLPCGVCPNCLTGLNHLCPN-IEIMGFHYDGGFAEY 120
Query: 406 Y-----KHAADFCFKLPDHVTMEEGALLEPLAVGIH 498
A KLPDH +E AL EPLA I+
Sbjct: 121 VLIPSKGVKAKVLNKLPDHFPIELAALTEPLACCIN 156
>UniRef50_A0UVE8 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Clostridium cellulolyticum H10|Rep: Alcohol
dehydrogenase GroES-like - Clostridium cellulolyticum
H10
Length = 348
Score = 58.0 bits (134), Expect = 2e-07
Identities = 46/137 (33%), Positives = 60/137 (43%), Gaps = 3/137 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQI-LQARSRFLL 431
V ++ VGDRVA P VPC C C+ G Y LC F + + + R+
Sbjct: 71 VTSVAVGDRVAGVPLVPCLKCGDCQKGDYALCKHYSFIGSRESGSFAEYVKMPERNVVKF 130
Query: 432 QAS*SRDHGR--RSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
S S + G AT A G GG V +LG G +G+ T A+ FGA +
Sbjct: 131 NDSVSFEQGAFFEPATVALHGLLCADYRGGED----VAILGGGTVGMFTAQWARIFGAKR 186
Query: 606 VLIIDILQSRLDFAKSL 656
V + DI RL AK L
Sbjct: 187 VFVFDIDNDRLALAKKL 203
Score = 57.2 bits (132), Expect = 3e-07
Identities = 49/162 (30%), Positives = 71/162 (43%), Gaps = 3/162 (1%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 225
+L+ +DLR + P EVL+R+ GICGSD+ G HF P+++GHE
Sbjct: 5 VLHARDDLRYEEILTPVPVKGEVLVRVKATGICGSDIPR-VLGDGAHFF---PIVLGHEF 60
Query: 226 SGVVAKIG---SKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNL 396
SG VA+IG + + V P P + G ++ D S + G+
Sbjct: 61 SGEVAEIGEGVTSVAVGDRVAGVPLVPCLKCG---DCQKGDYALCKHYSFIGSRE-SGSF 116
Query: 397 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESR 522
Y K K D V+ E+GA EP V +H A+ R
Sbjct: 117 AEYVKMPERNVVKFNDSVSFEQGAFFEPATVALHGLLCADYR 158
>UniRef50_Q9HWM8 Cluster: 2,3-butanediol dehydrogenase; n=24;
Proteobacteria|Rep: 2,3-butanediol dehydrogenase -
Pseudomonas aeruginosa
Length = 363
Score = 57.6 bits (133), Expect = 2e-07
Identities = 51/169 (30%), Positives = 80/169 (47%), Gaps = 10/169 (5%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIP-EISDDEVLLRMDCVGICGSDVHYWQKG------QCGHFV--L 195
A+ + +D+R+ P+P E V +R+ GICGSD+H + G + H + L
Sbjct: 14 AVWHGRHDIRVEDVPLPAEPPPGWVQIRVHWCGICGSDLHEYLAGPVFIPVEAPHPLTGL 73
Query: 196 EEPMIMGHEASGVVAKIGSKSRI*QLVIEWP*SPACR-VGTASSVRQDDTTYAPT*SSAP 372
++ I+GHE SG + ++G+ V + + AC+ GT R +
Sbjct: 74 KDQCILGHEFSGEIVRLGN-GVTGFAVGQAVAADACQHCGTCYYCRHGLYNICENLAFTG 132
Query: 373 RPQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAES 519
+G Y A+ + LP E GAL+EPLAVG+HA K+A S
Sbjct: 133 LMN-NGAFAEYVNVPANLLYALPAGFPSEAGALIEPLAVGMHAVKKAGS 180
Score = 51.2 bits (117), Expect = 2e-05
Identities = 37/128 (28%), Positives = 62/128 (48%), Gaps = 1/128 (0%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQI-LQARSRFLL 431
V VG VA + C C +C+ G Y++C ++ F + + A + L
Sbjct: 94 VTGFAVGQAVAADACQHCGTCYYCRHGLYNICENLAFTGLMNNGAFAEYVNVPANLLYAL 153
Query: 432 QAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVL 611
A + G A G H+ V++ G G V+V+GAG IGL T++ A+A GA +V+
Sbjct: 154 PAGFPSEAGALIEPLAV-GMHA-VKKAGSLLGQNVVVVGAGTIGLSTIMCARAAGAAQVI 211
Query: 612 IIDILQSR 635
+++ +R
Sbjct: 212 ALEMSSAR 219
>UniRef50_Q7UT38 Cluster: Zinc-type alcohol dehydrogenase; n=1;
Pirellula sp.|Rep: Zinc-type alcohol dehydrogenase -
Rhodopirellula baltica
Length = 342
Score = 57.6 bits (133), Expect = 2e-07
Identities = 42/134 (31%), Positives = 68/134 (50%), Gaps = 4/134 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM----IFCATPPVTRKPRQILQARSR 422
V+N+ VGDR ++EP + C+ C C+ G + C + C +T K IL AR
Sbjct: 73 VENVKVGDRCSVEPYINCQKCYSCERGLTNCCESHQTLGVMC-DGGLTEK--MILPARK- 128
Query: 423 FLLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAH 602
L + + + + + G + V+ VLV+G+GPIGL + A+ GA
Sbjct: 129 --LHPANNLSYEQSALVETLAIGCHAIDRAHVTEKDTVLVIGSGPIGLSAIEFARVAGA- 185
Query: 603 KVLIIDILQSRLDF 644
+V++ D+ Q+RLDF
Sbjct: 186 RVIVADLSQTRLDF 199
>UniRef50_Q7CVQ9 Cluster: AGR_L_281p; n=7; Alphaproteobacteria|Rep:
AGR_L_281p - Agrobacterium tumefaciens (strain C58 /
ATCC 33970)
Length = 397
Score = 57.6 bits (133), Expect = 2e-07
Identities = 43/138 (31%), Positives = 73/138 (52%), Gaps = 4/138 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCE-FCKTGRYHLCPDMIFCATPPVTRKPRQILQAR--SRF 425
V ++ VGDRV+I+P + R + F G +HL + A ++ + +A + +
Sbjct: 123 VTSVNVGDRVSIQPLIMPRSGDYFADRGLFHLSTQL---ALVGLSWDGGGMAEAALVNEY 179
Query: 426 LLQAS*SRDHGRRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAH 602
+Q +A P GGV+AG+ VLV GAGPIG+LT+L A+A GA
Sbjct: 180 NVQKIPDEMTDEEAALVEPSAVAVYACDRGGVTAGNSVLVTGAGPIGMLTLLAARAAGAT 239
Query: 603 KVLIIDILQSRLDFAKSL 656
++ + D+ +RL+ A+++
Sbjct: 240 QLFVSDLNDARLELARNV 257
Score = 47.2 bits (107), Expect = 3e-04
Identities = 48/172 (27%), Positives = 72/172 (41%), Gaps = 12/172 (6%)
Frame = +1
Query: 31 DNLTAL-LYKPNDLRLVQTPIPEI-SDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE- 201
+N+ AL + DLR+ P+ +VL+R VGICG+D+H + G F+ E
Sbjct: 39 ENMRALRFHAAKDLRIEDIAEPKRPGPGQVLVRNRFVGICGTDLHEYSYGPI--FIPTEP 96
Query: 202 --------PMIMGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT 357
P I+GHE GVV IG + P + + T
Sbjct: 97 HPFTGAHGPQILGHEFGGVVEAIGDGVTSVNVGDRVSIQPLIMPRSGDYFADRGLFHLST 156
Query: 358 *SSAPRPQLHGNLVRYYKHAADF-CFKLPDHVTMEEGALLEPLAVGIHACKR 510
+ G + ++ K+PD +T EE AL+EP AV ++AC R
Sbjct: 157 QLALVGLSWDGGGMAEAALVNEYNVQKIPDEMTDEEAALVEPSAVAVYACDR 208
>UniRef50_A4XUM5 Cluster: Alcohol dehydrogenase GroES domain
protein; n=2; Pseudomonas|Rep: Alcohol dehydrogenase
GroES domain protein - Pseudomonas mendocina ymp
Length = 422
Score = 57.6 bits (133), Expect = 2e-07
Identities = 46/150 (30%), Positives = 66/150 (44%), Gaps = 17/150 (11%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM---------IFCATPPVTRK--PR 398
+V+NL++GDRV + + C C +C+ G Y C + F P +T
Sbjct: 72 DVRNLSIGDRVVVPSTIACGNCAYCRAGYYAQCDEANPNGKEAGTSFYGGPEITGAFDGL 131
Query: 399 QILQARSRFL------LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPI 560
Q AR F L + S D + P G + + VS+G V V G GP+
Sbjct: 132 QAELARIPFANIGLVKLPSEISDDQAILLSDIFPTG-YFGAKLAEVSSGDTVAVFGCGPV 190
Query: 561 GLLTMLTAKAFGAHKVLIIDILQSRLDFAK 650
G + +AK GA +V ID L RLD A+
Sbjct: 191 GQFAIASAKLLGAARVFAIDHLDDRLDMAR 220
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/67 (34%), Positives = 41/67 (61%), Gaps = 1/67 (1%)
Frame = +1
Query: 64 DLRLVQTPIPEI-SDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 240
D+RL + P P++ + + ++R+ ICG+D+H+ +G G + + I+GHEA G+V
Sbjct: 11 DIRLDEVPEPQVQASTDAVIRITASAICGTDLHF-VRGTVGG--MRKGTILGHEAVGIVE 67
Query: 241 KIGSKSR 261
+GS R
Sbjct: 68 ALGSDVR 74
>UniRef50_Q8KQG6 Cluster: Mannitol dehydrogenase; n=12;
Bacteria|Rep: Mannitol dehydrogenase - Leuconostoc
mesenteroides
Length = 338
Score = 57.2 bits (132), Expect = 3e-07
Identities = 38/136 (27%), Positives = 62/136 (45%)
Frame = +1
Query: 91 PEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKSRI*Q 270
P++ +EVL+ GICG+D H G G P+++GHE SGVVA+IGS +
Sbjct: 20 PKVLPNEVLIHTAFAGICGTD-HALYAGLPGSADAVPPIVLGHENSGVVAEIGSAVTNVK 78
Query: 271 LVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADFCFKLPDHV 450
+ P G R SA G ++ A + +PD+V
Sbjct: 79 VGDRVTVDPNIYCGQCKYCRTARPELCEN-LSAVGVTRDGGFEEFFTAPASVVYPIPDNV 137
Query: 451 TMEEGALLEPLAVGIH 498
+++ A++EP++ +H
Sbjct: 138 SLKSAAVVEPISCAVH 153
Score = 44.4 bits (100), Expect = 0.002
Identities = 34/134 (25%), Positives = 60/134 (44%), Gaps = 2/134 (1%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKP--RQILQARSRFL 428
V N+ VGDRV ++P + C C++C+T R LC ++ + VTR + A + +
Sbjct: 74 VTNVKVGDRVTVDPNIYCGQCKYCRTARPELCENL---SAVGVTRDGGFEEFFTAPASVV 130
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
+ + +Q V+ LV+G G +G L + +A+G H+V
Sbjct: 131 YPIPDNVSLKSAAVVEPISCAVHGIQLLKVTPYQKALVIGDGFMGELFVQILQAYGIHQV 190
Query: 609 LIIDILQSRLDFAK 650
+ I+ +L K
Sbjct: 191 DLAGIVDEKLAMNK 204
>UniRef50_Q1AZ51 Cluster: Alcohol dehydrogenase GroES-like protein;
n=2; Bacteria|Rep: Alcohol dehydrogenase GroES-like
protein - Rubrobacter xylanophilus (strain DSM 9941 /
NBRC 16129)
Length = 357
Score = 57.2 bits (132), Expect = 3e-07
Identities = 29/72 (40%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Frame = +1
Query: 37 LTALLYK-PNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIM 213
+ A +Y+ P +LR+ P+PEI +VL+R+ GICGSD+H ++ G + IM
Sbjct: 7 MRAAVYRGPRELRVEPVPVPEIGPSDVLVRVHSCGICGSDLHSYKAG----MYIRPGQIM 62
Query: 214 GHEASGVVAKIG 249
GHE G VA G
Sbjct: 63 GHEFMGTVAAAG 74
Score = 54.8 bits (126), Expect = 2e-06
Identities = 47/141 (33%), Positives = 67/141 (47%), Gaps = 6/141 (4%)
Frame = +3
Query: 252 EVKNLTVGDRVA-IEPGVPCRYCEFCKTGRYHLCPDMIFCAT----PPVTRKPRQILQAR 416
+V+ + GDRV GV C C +C +Y LCP++ +T P + I A
Sbjct: 76 DVEGVEEGDRVTGFSIGV-CGSCYWCSRQQYILCPELFRNSTGYGLPGGFAEYVPIRNAV 134
Query: 417 SRFLLQAS*SRDHGRRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAF 593
+ S +AT P G ++ GV G V+VLGAG IG M A+A
Sbjct: 135 VGQSIHPVPSELDDETAATTEPVSVGVGAIEAAGVRPGDRVVVLGAGMIGNACMQAARAA 194
Query: 594 GAHKVLIIDILQSRLDFAKSL 656
GA +V +ID+ RL+ A+SL
Sbjct: 195 GAGQVAVIDVSPVRLEAARSL 215
>UniRef50_A5D5N1 Cluster: Threonine dehydrogenase and related
Zn-dependent dehydrogenases; n=1; Pelotomaculum
thermopropionicum SI|Rep: Threonine dehydrogenase and
related Zn-dependent dehydrogenases - Pelotomaculum
thermopropionicum SI
Length = 343
Score = 57.2 bits (132), Expect = 3e-07
Identities = 35/149 (23%), Positives = 68/149 (45%)
Frame = +1
Query: 55 KPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 234
+P + L P P + DEVL+R+ +CGSD+H ++ + F ++ P+I+GHE SG
Sbjct: 10 RPGAVNLRSVPEPRPAGDEVLIRVQSAAVCGSDLHAYEYPKSYEF-MKVPVILGHEYSGY 68
Query: 235 VAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKH 414
V +G + + + G + R+ T + + + G + +
Sbjct: 69 VEAVGPQVTLFKPGDRVLGESNRYCGVCPNCRRGRTNICDS-NLMTGLHVDGGMAEFIAV 127
Query: 415 AADFCFKLPDHVTMEEGALLEPLAVGIHA 501
+P++++ +E L +P +V HA
Sbjct: 128 PQKLVHHIPENLSFDEATLAQPCSVSFHA 156
>UniRef50_A1UG38 Cluster: Alcohol dehydrogenase GroES domain
protein; n=5; Actinomycetales|Rep: Alcohol dehydrogenase
GroES domain protein - Mycobacterium sp. (strain KMS)
Length = 362
Score = 57.2 bits (132), Expect = 3e-07
Identities = 39/132 (29%), Positives = 60/132 (45%), Gaps = 3/132 (2%)
Frame = +3
Query: 264 LTVGDRVAIEPGVPCRYCEFCKTGRYHLCP--DMI-FCATPPVTRKPRQILQARSRFLLQ 434
+ VGDRV E VPC C FCK G+YH+C D+ F P + A +
Sbjct: 95 IAVGDRVVSEQIVPCWECRFCKRGQYHMCQPHDLYGFKRRTPGAMASYMVYPAEALVHKV 154
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
+ + H A H+ V+ ++ V+V G GPIGL + A+A V+
Sbjct: 155 SKDIKPHHAAFAEPLSCSLHA-VERAQITFEDTVVVAGCGPIGLGMIAGARAKNPMHVIA 213
Query: 615 IDILQSRLDFAK 650
+D+ +L+ A+
Sbjct: 214 LDLAPDKLELAE 225
Score = 39.5 bits (88), Expect = 0.069
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 7/84 (8%)
Frame = +1
Query: 16 SDMATDNLTALL-YKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQK-----GQ 177
SD + + A++ + P D RL + +P+ E L+R++ VGIC SD+ + G
Sbjct: 2 SDQIPEKMQAVVCHGPRDYRLEEIAVPQRGPGEALIRVEAVGICASDLKCYHGAAKFWGD 61
Query: 178 CGHFVLEEPMIM-GHEASGVVAKI 246
E M++ GHE G V ++
Sbjct: 62 ENRPAWAETMVIPGHEFVGTVVEL 85
>UniRef50_Q5YU97 Cluster: Putative dehydrogenase; n=1; Nocardia
farcinica|Rep: Putative dehydrogenase - Nocardia
farcinica
Length = 340
Score = 56.8 bits (131), Expect = 4e-07
Identities = 44/156 (28%), Positives = 69/156 (44%)
Frame = +1
Query: 49 LYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 228
++ P + L +PE + ++ + GICGSD+ Y + G EPM +GHE S
Sbjct: 10 VHGPGTIGLDLVELPECGPRDAVVELRACGICGSDLGYIRLGGVAG-PGSEPMPLGHEIS 68
Query: 229 GVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYY 408
GVV+ IG++ R G V + +P L ++
Sbjct: 69 GVVSAIGAE------------VDGLRPGQRVVVHPGRDDIGRIGNGSPEGGLADAVLVRD 116
Query: 409 KHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
A D F +PD + + AL EP+AVG+HA +A+
Sbjct: 117 AAAGDRLFPIPDDMPFDVAALAEPVAVGMHAVDQAD 152
>UniRef50_A3Q0B4 Cluster: Alcohol dehydrogenase GroES domain
protein; n=4; Mycobacterium|Rep: Alcohol dehydrogenase
GroES domain protein - Mycobacterium sp. (strain JLS)
Length = 347
Score = 56.8 bits (131), Expect = 4e-07
Identities = 42/132 (31%), Positives = 62/132 (46%), Gaps = 3/132 (2%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIF--CATPPVTRKPRQILQARSRFLLQAS* 443
+G RV IEP + C +C C+ GRY++C +++ C T I R L
Sbjct: 83 LGTRVTIEPNLACGHCTQCRAGRYNICRELLVFGCQTAGALADSFTIPVDRVVALPDELD 142
Query: 444 SRDHGRRSATGAPRGGHSRVQE-GGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIID 620
R P R G V+V+GAGPIGL T+L A+ GA +V++ D
Sbjct: 143 DRHAILIEPLATPVHTVRRAAGLVGDLRDRAVVVIGAGPIGLFTLLAARHAGA-RVVVAD 201
Query: 621 ILQSRLDFAKSL 656
+L+S+ A+ L
Sbjct: 202 LLESKRARAERL 213
Score = 44.8 bits (101), Expect = 0.002
Identities = 41/136 (30%), Positives = 53/136 (38%), Gaps = 1/136 (0%)
Frame = +1
Query: 109 EVLLRMDCVGICGSDVHYWQKGQCG-HFVLEEPMIMGHEASGVVAKIGSKSRI*QLVIEW 285
EV + VGICGSD+H CG H ++ P GHEA GVV +G+ L
Sbjct: 32 EVRVGTSLVGICGSDLH----AACGRHPFIDLPYRPGHEAVGVVDAVGAGVDESWLGTRV 87
Query: 286 P*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADFCFKLPDHVTMEEG 465
P G + R Q G L + D LPD +
Sbjct: 88 TIEPNLACGHCTQCRAGRYNICRE-LLVFGCQTAGALADSFTIPVDRVVALPDELDDRHA 146
Query: 466 ALLEPLAVGIHACKRA 513
L+EPLA +H +RA
Sbjct: 147 ILIEPLATPVHTVRRA 162
>UniRef50_A2UF68 Cluster: Alcohol dehydrogenase GroES domain
protein; n=10; Proteobacteria|Rep: Alcohol dehydrogenase
GroES domain protein - Escherichia coli B
Length = 336
Score = 56.8 bits (131), Expect = 4e-07
Identities = 37/125 (29%), Positives = 62/125 (49%), Gaps = 2/125 (1%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLC-PDMIFCATPPVTRKPRQILQARSRFL 428
+VKN+ GD V ++P + C C CK GR++LC P + P + + I+ AR+ +
Sbjct: 76 DVKNVQPGDHVVVDPIMACMECRACKAGRFNLCEPPQVAGFRAPGFARSQHIVPARNCHV 135
Query: 429 LQAS*S-RDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
AS + R +R+ + + + VLV+GAG IGL + + GA K
Sbjct: 136 APASLPLKVLAFAEPAACARHCVNRMPKASLES---VLVIGAGTIGLSIVQALRIMGAGK 192
Query: 606 VLIID 620
+ +I+
Sbjct: 193 ITVIE 197
Score = 41.5 bits (93), Expect = 0.017
Identities = 23/59 (38%), Positives = 33/59 (55%)
Frame = +1
Query: 76 VQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 252
V+ P E+ EV + GICGSD+H KG GH + P++ GHE + V ++GS
Sbjct: 20 VEVPHQELKPHEVRIAPVFYGICGSDLHV-LKG--GHPFAKPPVVPGHEIAARVTEVGS 75
>UniRef50_Q97TZ4 Cluster: Sorbitol dehydrogenase; n=4;
Sulfolobaceae|Rep: Sorbitol dehydrogenase - Sulfolobus
solfataricus
Length = 345
Score = 56.8 bits (131), Expect = 4e-07
Identities = 45/155 (29%), Positives = 71/155 (45%), Gaps = 11/155 (7%)
Frame = +1
Query: 79 QTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKS 258
+ P+P++ +VL++M G+CG+D+ + CG + +P I+GHE +G++
Sbjct: 22 ELPLPKLQQGDVLVKMKACGLCGTDI----EKICGQYTASQP-ILGHEPTGIIQ------ 70
Query: 259 RI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLH------GNLVRYYK--- 411
+ ++W P RV V + Y S P G Y++
Sbjct: 71 ---ESTVDWL-KPGDRVFAHHHVPCYECYYCKKGSPTMCPYYRKTNLDPGGFSEYFRVPA 126
Query: 412 --HAADFCFKLPDHVTMEEGALLEPLAVGIHACKR 510
A KLPD+V+ EEGA +EPLA I A KR
Sbjct: 127 WNVARGGVLKLPDNVSFEEGAFIEPLATVIRAQKR 161
Score = 40.7 bits (91), Expect = 0.030
Identities = 38/133 (28%), Positives = 53/133 (39%), Gaps = 6/133 (4%)
Frame = +3
Query: 264 LTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPP-----VTRKPRQILQARSRFL 428
L GDRV VPC C +CK G +CP P R P +
Sbjct: 77 LKPGDRVFAHHHVPCYECYYCKKGSPTMCPYYRKTNLDPGGFSEYFRVPAWNVARGGVLK 136
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEG-GVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
L + S + G A P R Q+ + G V ++G GP+GLL + AK A
Sbjct: 137 LPDNVSFEEG---AFIEPLATVIRAQKRVAIDNGDTVFIVGIGPMGLLHAMMAKVNKAGV 193
Query: 606 VLIIDILQSRLDF 644
++ D+ R +F
Sbjct: 194 IIASDVSDFRTEF 206
>UniRef50_Q72U55 Cluster: Zinc binding dehydrogenase; n=4;
Leptospira|Rep: Zinc binding dehydrogenase - Leptospira
interrogans serogroup Icterohaemorrhagiae
serovarcopenhageni
Length = 348
Score = 56.4 bits (130), Expect = 6e-07
Identities = 35/132 (26%), Positives = 56/132 (42%), Gaps = 1/132 (0%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVTRKPRQILQARSRFLL 431
V+ GDRV I G C C +CK G+ +LC D+ +F + I++ R + L
Sbjct: 79 VRRFRKGDRVVIAAGTSCGVCSYCKEGKENLCKDLGVFGFDRDGSFAEFNIVEERYLYSL 138
Query: 432 QAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVL 611
D G A H+ G + V + G G +G+ + A+A KV+
Sbjct: 139 PDEIPFDQGAILADAVSTPYHAIRYRGNIQESDTVAIFGCGGLGIHAVAIARAMTKGKVI 198
Query: 612 IIDILQSRLDFA 647
+D+ L+ A
Sbjct: 199 ALDVDSGALENA 210
Score = 51.2 bits (117), Expect = 2e-05
Identities = 24/67 (35%), Positives = 39/67 (58%), Gaps = 2/67 (2%)
Frame = +1
Query: 67 LRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKG--QCGHFVLEEPMIMGHEASGVVA 240
L + +P++ ++V +R+ GICGSDVH G +C HF P + GHE+SG++
Sbjct: 18 LEIRDVSVPQLRAEQVKVRIKACGICGSDVHLVVHGTLKCKHF----PRVPGHESSGIIE 73
Query: 241 KIGSKSR 261
++G R
Sbjct: 74 EVGENVR 80
>UniRef50_Q1IQV5 Cluster: Alcohol dehydrogenase, zinc-binding; n=2;
Acidobacteria|Rep: Alcohol dehydrogenase, zinc-binding -
Acidobacteria bacterium (strain Ellin345)
Length = 345
Score = 56.4 bits (130), Expect = 6e-07
Identities = 21/69 (30%), Positives = 44/69 (63%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A+LY D+R+ + P+P++ + E+L+++ CG+DV +++G ++ P + GHE
Sbjct: 4 AVLYGKEDVRIEKVPVPKVGEGEILVKVQVALTCGTDVKVYRRGYHARMIV-PPALFGHE 62
Query: 223 ASGVVAKIG 249
+G+V ++G
Sbjct: 63 LAGIVEEVG 71
Score = 47.2 bits (107), Expect = 3e-04
Identities = 39/137 (28%), Positives = 65/137 (47%), Gaps = 3/137 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIF--CATPPVTRKPRQILQARSRFL 428
VK L G RV PC C +C + +LC D++F A P++I++ ++ +
Sbjct: 74 VKRLKKGMRVVALNSAPCGVCFYCSKHQENLCEDLLFNNGAYAEYILIPKRIVE-KNLLV 132
Query: 429 LQAS*SRDHGRRSATGAPRGGHSR-VQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
+ S D +A P R + E G+ G + V+GAGPIGL+ + A G K
Sbjct: 133 IPDGVSFD---EAAVIEPLACVLRGLHETGMEVGDTITVIGAGPIGLMFVKAASISGC-K 188
Query: 606 VLIIDILQSRLDFAKSL 656
V+ + +++ AK +
Sbjct: 189 VISVVKHDEQVEAAKKM 205
>UniRef50_Q3B3S5 Cluster: Alcohol dehydrogenase, zinc-containing;
n=1; Pelodictyon luteolum DSM 273|Rep: Alcohol
dehydrogenase, zinc-containing - Pelodictyon luteolum
(strain DSM 273) (Chlorobium luteolum (strain DSM273))
Length = 323
Score = 56.0 bits (129), Expect = 7e-07
Identities = 44/155 (28%), Positives = 62/155 (40%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 225
LL P L ++ PIP + EVLLR+ IC +D W GH L P ++GHE
Sbjct: 5 LLCGPKSLSILDRPIPIPGEGEVLLRVRAAAICRTDAKMWSS---GHRDLRLPRVLGHEV 61
Query: 226 SGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRY 405
SG + G+ QL WP AC G+ + R P G +
Sbjct: 62 SGTIE--GNPG---QLYALWP-GQAC--GSCMACRSGRQNLCPD-MRITGFHRDGGFAEF 112
Query: 406 YKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKR 510
++P+ V L EPLA +H ++
Sbjct: 113 LTAPRSSLLEVPEGVGPVMATLAEPLACAVHGVRQ 147
Score = 50.4 bits (115), Expect = 4e-05
Identities = 37/113 (32%), Positives = 49/113 (43%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SRD 452
G A+ PG C C C++GR +LCPDM + RS L
Sbjct: 70 GQLYALWPGQACGSCMACRSGRQNLCPDMRITGFHRDGGFAEFLTAPRSSLLEVPEGVGP 129
Query: 453 HGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVL 611
A H V++GGVS+ VL+ GAG +GLL L A+ GA V+
Sbjct: 130 VMATLAEPLACAVHG-VRQGGVSSRERVLIYGAGTLGLLVALVARECGASVVM 181
>UniRef50_Q5HLF5 Cluster: Sorbitol dehydrogenase, putative; n=10;
Bacilli|Rep: Sorbitol dehydrogenase, putative -
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Length = 350
Score = 55.6 bits (128), Expect = 1e-06
Identities = 27/52 (51%), Positives = 36/52 (69%)
Frame = +3
Query: 501 VQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
V+EG + G V V GAGPIGLLT++ AKA GA K+ + D+ + RL AKS+
Sbjct: 160 VKEGELLFGDTVAVFGAGPIGLLTIVAAKAAGASKIFVFDLSEERLAKAKSV 211
Score = 50.8 bits (116), Expect = 3e-05
Identities = 47/171 (27%), Positives = 74/171 (43%), Gaps = 13/171 (7%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE------- 201
A+ Y D+R+ I D+EV +++ GICG+D+H + +G F+ +
Sbjct: 4 AVWYGQKDVRVEDREPKAIKDNEVQVKVSWAGICGTDLHEYLEGPI--FISTDQPDPLLG 61
Query: 202 ---PMIMGHEASGVVAKIG---SKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*S 363
P+ +GHE SGVV +G S+ + V+ P T S + +
Sbjct: 62 QTAPVTLGHEFSGVVENVGKDVSRFKKGDRVVVNP--------TVSKREKPENVDLYDGY 113
Query: 364 SAPRPQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
S G + + LPD+V+ EGAL+EP AV + A K E
Sbjct: 114 SFIGLGSDGAFAEFTNAPETNVYHLPDNVSAREGALVEPTAVAVQAVKEGE 164
>UniRef50_Q565X2 Cluster: 6-hydroxycylohex-1-ene-1-carboxyl-CoA
dehydrogenase; n=1; uncultured bacterium|Rep:
6-hydroxycylohex-1-ene-1-carboxyl-CoA dehydrogenase -
uncultured bacterium
Length = 340
Score = 55.6 bits (128), Expect = 1e-06
Identities = 23/66 (34%), Positives = 42/66 (63%)
Frame = +1
Query: 55 KPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 234
K L++ P+P+I D++L+++ G+C +D+HY + G + P+++GHEASG+
Sbjct: 9 KDAGLKIEDIPVPQIKGDQILVKVAACGVCHTDLHYIEHGV--PTFKKPPIVLGHEASGI 66
Query: 235 VAKIGS 252
V K G+
Sbjct: 67 VEKAGA 72
>UniRef50_Q2AGV2 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=1; Halothermothrix orenii H 168|Rep:
Zinc-containing alcohol dehydrogenase superfamily -
Halothermothrix orenii H 168
Length = 336
Score = 55.6 bits (128), Expect = 1e-06
Identities = 40/159 (25%), Positives = 73/159 (45%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 225
+ Y P ++++ IP+I ++EVL+++ GICG+D H ++ G +I+GHE
Sbjct: 5 VFYGPGNVKIEDKEIPKIDENEVLVKVKAAGICGTDRHIYR----GEAPARTQVILGHEN 60
Query: 226 SGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRY 405
+G + + G + R + + P G + + A +G Y
Sbjct: 61 AGEIIETGRQVRSLKKGDKVCIDPNIFCGQCYYCHRGEVHLCKE-LQAIGVTRNGGFAEY 119
Query: 406 YKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESR 522
A +K+ ++V+ +E AL+EPLA +H A R
Sbjct: 120 LVAPATNVYKVKENVSYKEMALVEPLACCLHGIDLAGIR 158
Score = 50.4 bits (115), Expect = 4e-05
Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 2/123 (1%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKP--RQILQARSRF 425
+V++L GD+V I+P + C C +C G HLC ++ VTR + L A +
Sbjct: 70 QVRSLKKGDKVCIDPNIFCGQCYYCHRGEVHLCKEL---QAIGVTRNGGFAEYLVAPATN 126
Query: 426 LLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
+ + + + + + G+ G V++LGAG IGL+ + A GA +
Sbjct: 127 VYKVKENVSYKEMALVEPLACCLHGIDLAGIRPGDFVVILGAGAIGLILLQLALHSGASE 186
Query: 606 VLI 614
V++
Sbjct: 187 VIV 189
>UniRef50_A4AMR5 Cluster: Zn-dependent alcohol dehydrogenase; n=2;
Flavobacteriales|Rep: Zn-dependent alcohol dehydrogenase
- Flavobacteriales bacterium HTCC2170
Length = 337
Score = 55.6 bits (128), Expect = 1e-06
Identities = 39/133 (29%), Positives = 59/133 (44%)
Frame = +3
Query: 258 KNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQA 437
K L GD+V I P V C C C+ G+ + C +M ++ + LL+A
Sbjct: 73 KGLKAGDKVVIMPYVSCNTCIACRNGKNNCCTNMQVLGI-HTDGGMQEKINVPIELLLKA 131
Query: 438 S*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLII 617
+ D G H+ + G+S +V+G GPIGL M A+ G +++ I
Sbjct: 132 NELTDDEIAIVEPLAIGAHA-ISRSGLSKDETAVVVGCGPIGLGIMKLAQLEGV-QIIAI 189
Query: 618 DILQSRLDFAKSL 656
D RL FAK +
Sbjct: 190 DNNSERLSFAKEI 202
Score = 42.3 bits (95), Expect = 0.010
Identities = 38/158 (24%), Positives = 63/158 (39%)
Frame = +1
Query: 55 KPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 234
KP L + P LL+++ VGICG+D+H + Q P I+GHE +
Sbjct: 8 KPGKFLLKEKKAPLGVKGHALLKINKVGICGTDLHAYAGNQA---FFTYPRILGHELAAE 64
Query: 235 VAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKH 414
+ I + + + + P T + R T G +
Sbjct: 65 IISIPTNQKGLKAGDKVVIMPYVSCNTCIACRNGKNNCC-TNMQVLGIHTDGGMQEKINV 123
Query: 415 AADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESRRD 528
+ K + +T +E A++EPLA+G HA R+ +D
Sbjct: 124 PIELLLK-ANELTDDEIAIVEPLAIGAHAISRSGLSKD 160
>UniRef50_A3U1C0 Cluster: Threonine 3-dehydrogenase; n=1; Oceanicola
batsensis HTCC2597|Rep: Threonine 3-dehydrogenase -
Oceanicola batsensis HTCC2597
Length = 349
Score = 55.6 bits (128), Expect = 1e-06
Identities = 51/157 (32%), Positives = 71/157 (45%), Gaps = 7/157 (4%)
Frame = +1
Query: 67 LRLVQTPIPEISD-DEVLLRMDCVGICGSDVHY--WQKGQCGHFVLEE-PMIMGHEASGV 234
L L P P + EV +R++ VGICGSD+H W G F+L P+ +GHE +G+
Sbjct: 13 LSLDDCPAPGAPEAGEVTVRVEAVGICGSDLHVADWSGGY--DFMLPHLPLTLGHEFAGI 70
Query: 235 VAKIG-SKSRI--*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRY 405
+ G +R+ V WP SP ++ R+ + T R LV
Sbjct: 71 IEATGPGVARVTPGDRVTIWPSSPCDTCPECTAGRRRNCRNKAT-LGLYRDGAFAPLVTA 129
Query: 406 YKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
A F +PD ++ E AL EPL VG A K E
Sbjct: 130 RAQGA---FTIPDALSFEIAALTEPLCVGRRAVKTGE 163
Score = 46.0 bits (104), Expect = 8e-04
Identities = 39/120 (32%), Positives = 53/120 (44%), Gaps = 2/120 (1%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKP--RQILQARSRFL 428
V +T GDRV I P PC C C GR C + AT + R ++ AR++
Sbjct: 78 VARVTPGDRVTIWPSSPCDTCPECTAGRRRNCRNK---ATLGLYRDGAFAPLVTARAQGA 134
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
+ + T G V+ G VS G VLVLG G IG + A+A GA ++
Sbjct: 135 FTIPDALSFEIAALTEPLCVGRRAVKTGEVSPGDRVLVLGPGTIGQSIAVFARAAGAAQI 194
>UniRef50_Q0CVZ1 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 386
Score = 55.6 bits (128), Expect = 1e-06
Identities = 44/163 (26%), Positives = 73/163 (44%)
Frame = +1
Query: 34 NLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIM 213
N + +L + + + P+P + D VL+++ GICGSD+H + G G +M
Sbjct: 23 NTSCVLVEKRRISIEPIPMPILQPDGVLVKVIANGICGSDMHVYLSGGIGGRGAYGRTVM 82
Query: 214 GHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGN 393
GHEA+G V +G + P RV S + + R + +
Sbjct: 83 GHEAAGEVIAVGEHVTTHK--------PGDRVAVISVLM--------CAIAVLRGTMDLS 126
Query: 394 LVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESR 522
++ AD +P+ V+ EE ++PLA+GI KRA+ R
Sbjct: 127 RGMFFALPADMAPHIPETVSWEEAGSIQPLAIGIQIGKRADLR 169
Score = 39.9 bits (89), Expect = 0.053
Identities = 19/43 (44%), Positives = 26/43 (60%)
Frame = +3
Query: 522 AGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAK 650
A V + G GPIGL+T A A+ A K++ +I SR+ FAK
Sbjct: 170 AHQTVAIFGCGPIGLITAAVAHAYCAAKIIAFEINPSRVAFAK 212
>UniRef50_UPI00015970BD Cluster: GutB1; n=1; Bacillus
amyloliquefaciens FZB42|Rep: GutB1 - Bacillus
amyloliquefaciens FZB42
Length = 348
Score = 55.2 bits (127), Expect = 1e-06
Identities = 44/162 (27%), Positives = 72/162 (44%), Gaps = 3/162 (1%)
Frame = +1
Query: 37 LTALLYKPND-LRLVQTPIPEI-SDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 210
+ AL++ PND L + P+I ++V +++ GICG+D++ + G MI
Sbjct: 1 MKALVWTPNDKLEYQEVDEPQIRKSNDVKVKIFGTGICGTDLNVLK----GKMNATHHMI 56
Query: 211 MGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRP-QLH 387
MGHE+ G V +IG ++ P G R+ T Y T H
Sbjct: 57 MGHESVGAVVEIGPDVTNVKVGDRVVIDPTQFCGKCHYCRRGLTCYCETFEDWQLGIGAH 116
Query: 388 GNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
G YY F +++PD + E L+EPL+ ++ +A
Sbjct: 117 GTFAEYYVGEDRFMYRIPDSMEWERATLVEPLSCVLNVVDKA 158
Score = 41.9 bits (94), Expect = 0.013
Identities = 31/113 (27%), Positives = 46/113 (40%), Gaps = 1/113 (0%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKP-RQILQARSRFL 428
+V N+ VGDRV I+P C C +C+ G C + RF+
Sbjct: 71 DVTNVKVGDRVVIDPTQFCGKCHYCRRGLTCYCETFEDWQLGIGAHGTFAEYYVGEDRFM 130
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAK 587
+ S + R + + V + + VLVLG+GPIGLL + K
Sbjct: 131 YRIPDSMEWERATLVEPLSCVLNVVDKASIQPEDSVLVLGSGPIGLLVQMMVK 183
>UniRef50_Q987C5 Cluster: Alcohol dehydrogenase; n=4;
Rhizobiales|Rep: Alcohol dehydrogenase - Rhizobium loti
(Mesorhizobium loti)
Length = 341
Score = 55.2 bits (127), Expect = 1e-06
Identities = 30/70 (42%), Positives = 39/70 (55%), Gaps = 1/70 (1%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDE-VLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 219
A LY P DLR+ P I D V LR+D GICGSD+H ++ GQ ++ P GH
Sbjct: 4 ARLYGPGDLRVEDVAPPGIPDPGWVKLRVDAAGICGSDLHNFRTGQ---WISRSPSTAGH 60
Query: 220 EASGVVAKIG 249
E +G V +G
Sbjct: 61 ELTGTVTALG 70
Score = 44.8 bits (101), Expect = 0.002
Identities = 43/130 (33%), Positives = 61/130 (46%), Gaps = 3/130 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQ-ILQARSRFLL 431
V + VGDRV + C C C+ GR HLC + F Q +L AR ++
Sbjct: 73 VDTVAVGDRVVADSRFWCEECVQCRAGRRHLCASLGFVGEVCDGGFAEQVVLPARLLHVV 132
Query: 432 QAS*SRDHGRRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPI-GLLTMLTAKAFGAHK 605
A+ R +A P V+ +AG VLV+G GPI GL +L +++F A
Sbjct: 133 DAALDE---RVAAMAEPLAVALHAVRRLPKTAGS-VLVVGCGPIGGLAALLLSRSF-AGT 187
Query: 606 VLIIDILQSR 635
VL+ D Q+R
Sbjct: 188 VLVADRNQAR 197
>UniRef50_Q8DK96 Cluster: Tll0970 protein; n=6; Cyanobacteria|Rep:
Tll0970 protein - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 373
Score = 55.2 bits (127), Expect = 1e-06
Identities = 46/165 (27%), Positives = 72/165 (43%), Gaps = 8/165 (4%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHF-VLEEPMIMGH 219
A+LY D+R+ P P EV++R+ CG+D+ W++G GH +L P++ GH
Sbjct: 28 AVLYGKEDVRIETVPDPTPGPGEVVIRVRAATTCGTDLKVWRRG--GHARMLTPPILFGH 85
Query: 220 EASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQL---HG 390
EA+G + +G+ V W RV +S Y + + P L +G
Sbjct: 86 EAAGEIVALGAG------VTGW--QVGDRVVANNSAPCGQCFYCQRQAFSLCPHLEFNNG 137
Query: 391 NLVRYYKHAADF----CFKLPDHVTMEEGALLEPLAVGIHACKRA 513
Y K A +P+ + AL EPLA +H R+
Sbjct: 138 TFAEYLKLPASIVRQNLLPIPESLPFALAALTEPLACVLHGVARS 182
Score = 34.7 bits (76), Expect = 2.0
Identities = 13/32 (40%), Positives = 17/32 (53%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIF 365
VGDRV PC C +C+ + LCP + F
Sbjct: 103 VGDRVVANNSAPCGQCFYCQRQAFSLCPHLEF 134
>UniRef50_Q0RW76 Cluster: Probable Zn-containing alcohol
dehydrogenase; n=1; Rhodococcus sp. RHA1|Rep: Probable
Zn-containing alcohol dehydrogenase - Rhodococcus sp.
(strain RHA1)
Length = 353
Score = 55.2 bits (127), Expect = 1e-06
Identities = 46/170 (27%), Positives = 70/170 (41%), Gaps = 6/170 (3%)
Frame = +1
Query: 37 LTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKG----QCGHFVLEE- 201
L LY+ +D RL + P PE+ V +++ GICGSD+ ++ + +++E
Sbjct: 2 LALRLYREHDARLEEVPEPELRPGAVKVKVAWAGICGSDLSLFETAPVPLDYSNPIMQET 61
Query: 202 -PMIMGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRP 378
P +GHE SG V ++ Q+ P GT S + +
Sbjct: 62 GPHTLGHEFSGYVTEVAEGVTTVQVGDLVAVRPNFADGTCPSCQAGHPNMCDNFAFIGIN 121
Query: 379 QLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESRRD 528
G AD + LP + AL+EPL V HA K AE +D
Sbjct: 122 GWGGGFSESVVVPADHAYVLPPGFNAQIAALIEPLTVAWHAVKLAEIPKD 171
Score = 37.9 bits (84), Expect = 0.21
Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 3/134 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTR--KPRQILQARSRFL 428
V + VGD VA+ P C C+ G ++C + F ++ A ++
Sbjct: 81 VTTVQVGDLVAVRPNFADGTCPSCQAGHPNMCDNFAFIGINGWGGGFSESVVVPADHAYV 140
Query: 429 LQAS*SRDHGRRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
L + + +A P V+ + LV+GAGPIGL T+L +A G K
Sbjct: 141 LPPG---FNAQIAALIEPLTVAWHAVKLAEIPKDGTALVVGAGPIGLSTVLALRAQGISK 197
Query: 606 VLIIDILQSRLDFA 647
+++ + ++R A
Sbjct: 198 IIVSEPSEARKKLA 211
>UniRef50_Q5HRD6 Cluster: Alcohol dehydrogenase; n=106;
Bacteria|Rep: Alcohol dehydrogenase - Staphylococcus
epidermidis (strain ATCC 35984 / RP62A)
Length = 340
Score = 55.2 bits (127), Expect = 1e-06
Identities = 41/136 (30%), Positives = 64/136 (47%), Gaps = 2/136 (1%)
Frame = +3
Query: 255 VKNLTVGDRVAIE-PGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLL 431
V +L VGDRV+I C CE+C TGR LC D++ +++ + + +
Sbjct: 71 VDSLKVGDRVSIAWMYAACGNCEYCTTGRETLCRDVLNAGYTVDGAMAEEVI-VDANYAV 129
Query: 432 QAS*SRDHGRRSA-TGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
+ + D S+ T A + V+ G+ G + V G G +G L + AK KV
Sbjct: 130 KVPENLDPAAASSITCAGVTTYKAVKVSGIEPGQWLGVFGVGGLGNLALQYAKNVMGAKV 189
Query: 609 LIIDILQSRLDFAKSL 656
+ DI +L+FAK L
Sbjct: 190 VAFDINDDKLNFAKEL 205
>UniRef50_Q3IVK2 Cluster: Zinc-containing alcohol dehydrogenase;
n=1; Rhodobacter sphaeroides 2.4.1|Rep: Zinc-containing
alcohol dehydrogenase - Rhodobacter sphaeroides (strain
ATCC 17023 / 2.4.1 / NCIB 8253 / DSM158)
Length = 337
Score = 54.8 bits (126), Expect = 2e-06
Identities = 26/63 (41%), Positives = 38/63 (60%)
Frame = +1
Query: 67 LRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 246
LRL PI E DEVL+R+D ICG+D H + G F + P+++GHE +G V ++
Sbjct: 12 LRLTDLPIQEPGPDEVLIRIDSATICGTDQHILE----GKFWAKPPVVLGHEFAGYVERV 67
Query: 247 GSK 255
G +
Sbjct: 68 GER 70
Score = 48.0 bits (109), Expect = 2e-04
Identities = 37/123 (30%), Positives = 55/123 (44%), Gaps = 3/123 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V+N GD V++EP V C C+ C+ G+ HLC D + + Q R + Q
Sbjct: 71 VQNCRPGDLVSVEPHVYCGCCKPCRLGKPHLCLDRLAWGI-NLNGGFEQYATVRMDTVYQ 129
Query: 435 AS*S---RDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
+ TG G RV GV G +V++LG G GL+ A+ GA +
Sbjct: 130 VPEGIGPEEAALGEITGCCMHGIDRV---GVELGDLVVILGGGAAGLILARLAELRGAAR 186
Query: 606 VLI 614
++I
Sbjct: 187 IVI 189
>UniRef50_O35045 Cluster: Zinc-containing alcohol dehydrogenase;
n=5; Bacillus|Rep: Zinc-containing alcohol dehydrogenase
- Bacillus subtilis
Length = 339
Score = 54.8 bits (126), Expect = 2e-06
Identities = 45/135 (33%), Positives = 62/135 (45%), Gaps = 3/135 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVTRKPRQILQARSRFLL 431
V++L GD V IEP C C C+ GR ++C + +F + +L R +
Sbjct: 73 VQSLKPGDHVVIEPISYCGSCYACRKGRPNVCAKLSVFGVHEDGGMREYIVLPERQLHAV 132
Query: 432 QAS*SRDHGRRSATGAPRG--GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
S+D A A G V G V G VL+ GAGPIG+ + AK GA
Sbjct: 133 ----SKDLPWEEAVMAEPYTIGAQAVWRGQVEKGDTVLIQGAGPIGICVLKMAKLAGA-A 187
Query: 606 VLIIDILQSRLDFAK 650
V++ D+ RL FAK
Sbjct: 188 VMMTDLNNERLAFAK 202
Score = 44.8 bits (101), Expect = 0.002
Identities = 27/67 (40%), Positives = 39/67 (58%), Gaps = 1/67 (1%)
Frame = +1
Query: 55 KPNDLRLVQTPIPEIS-DDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASG 231
K DL + P +S DDEVL+++ VGICGSD+H + G L P ++GHE +G
Sbjct: 8 KAYDLVTAEVKKPVLSKDDEVLVKVKRVGICGSDMHIYH-GTNPLATL--PRVIGHEVTG 64
Query: 232 VVAKIGS 252
V +G+
Sbjct: 65 QVEAVGA 71
>UniRef50_Q59715 Cluster: Benzyl alcohol dehydrogenase II; n=5;
Pseudomonas|Rep: Benzyl alcohol dehydrogenase II -
Pseudomonas putida
Length = 348
Score = 54.4 bits (125), Expect = 2e-06
Identities = 45/137 (32%), Positives = 64/137 (46%), Gaps = 2/137 (1%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLL 431
+VK L G RV++E +PC C C+ G H+CP + ++ S +
Sbjct: 76 DVKGLRPGMRVSLESHLPCGTCYTCRRGWAHVCPKTRYPGVDFDGGFASFVVVPES--VC 133
Query: 432 QAS*SRDHGRRSATGAPRG--GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
++A P G H+ ++ GVS G VLV G GPIGL+ + AKA GA K
Sbjct: 134 WPVPCGIPPLQAAMMEPFGLAVHASLEGSGVS-GLNVLVSGCGPIGLMNIAAAKALGASK 192
Query: 606 VLIIDILQSRLDFAKSL 656
V+ DI RL A +
Sbjct: 193 VIAPDIHPLRLTAAAKM 209
Score = 52.4 bits (120), Expect = 9e-06
Identities = 35/149 (23%), Positives = 67/149 (44%), Gaps = 1/149 (0%)
Frame = +1
Query: 58 PNDLRLVQTPIP-EISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 234
P L + P E +VL++++ GICG+D+ ++ G+ ++ P I+GHE SGV
Sbjct: 11 PGGLSVDDVAAPKEAHSTDVLVKVEAAGICGTDLLIYKWGEFAKR-MKLPTILGHEVSGV 69
Query: 235 VAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKH 414
+ ++GS + + + GT + R+ P + P G +
Sbjct: 70 IEQVGSDVKGLRPGMRVSLESHLPCGTCYTCRRGWAHVCPK-TRYPGVDFDGGFASFVVV 128
Query: 415 AADFCFKLPDHVTMEEGALLEPLAVGIHA 501
C+ +P + + A++EP + +HA
Sbjct: 129 PESVCWPVPCGIPPLQAAMMEPFGLAVHA 157
>UniRef50_Q5BBC2 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 353
Score = 54.4 bits (125), Expect = 2e-06
Identities = 44/157 (28%), Positives = 68/157 (43%), Gaps = 7/157 (4%)
Frame = +1
Query: 64 DLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCG-----HFV--LEEPMIMGHE 222
D+R+ Q P ++ +V +R VGICGSD+H + G H + + P+ +GHE
Sbjct: 11 DIRVDQIDEPSCAEGQVKIRPAFVGICGSDLHEYLSGPIAIPTTPHPLTGAQLPVTLGHE 70
Query: 223 ASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVR 402
SG + ++G ++ P GT +S + G L
Sbjct: 71 FSGTIEEVGQGVTGFKVGDRVAVRPNLSDGTCASCVYGRPNCCRSLGFIGFSSNSGGLSD 130
Query: 403 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
Y A LP+ V ++ GAL+EPL V HA R+
Sbjct: 131 YVTVPAKHAILLPESVPLDLGALVEPLTVAWHAVARS 167
Score = 43.6 bits (98), Expect = 0.004
Identities = 37/136 (27%), Positives = 55/136 (40%), Gaps = 2/136 (1%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFC--ATPPVTRKPRQILQARSRFL 428
V VGDRVA+ P + C C GR + C + F ++ + A+ L
Sbjct: 82 VTGFKVGDRVAVRPNLSDGTCASCVYGRPNCCRSLGFIGFSSNSGGLSDYVTVPAKHAIL 141
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
L S D G H+ V LV+G GPIGL + KA G V
Sbjct: 142 LPESVPLDLG-ALVEPLTVAWHA-VARSPHETARTALVVGGGPIGLAVVQVLKARGVQTV 199
Query: 609 LIIDILQSRLDFAKSL 656
++ ++ R ++A +L
Sbjct: 200 VVAEVSTQRREYALTL 215
>UniRef50_UPI000050F926 Cluster: COG1063: Threonine dehydrogenase
and related Zn-dependent dehydrogenases; n=1;
Brevibacterium linens BL2|Rep: COG1063: Threonine
dehydrogenase and related Zn-dependent dehydrogenases -
Brevibacterium linens BL2
Length = 328
Score = 54.0 bits (124), Expect = 3e-06
Identities = 33/111 (29%), Positives = 47/111 (42%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SR 449
VGDRVA+EP + C CE+C+ G C + +++ S F +
Sbjct: 79 VGDRVALEPNITCGRCEYCRRGMTSACTSRLSAGVLTQPGFLAEVVDHPSEFCHRLDAHM 138
Query: 450 DHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAH 602
R S ++ + VLVLGAG GLL++LT A G H
Sbjct: 139 SLERAVCAEPLAVAASAIRRTDLQGSETVLVLGAGAQGLLSILTLVAQGHH 189
Score = 52.4 bits (120), Expect = 9e-06
Identities = 42/162 (25%), Positives = 71/162 (43%), Gaps = 3/162 (1%)
Frame = +1
Query: 40 TALLYKPNDLRLVQTPIPE--ISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMI 210
+A + P + +V +P+ + ++ +RM VGICG+D Q G + P
Sbjct: 3 SAEITAPGRVEIVDRSLPQGLVGRGDLRIRMLAVGICGTD----QTLATGRRTPPQLPWR 58
Query: 211 MGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHG 390
+GHE G +A++G + + P G R+ T+ + SA G
Sbjct: 59 LGHEGIGEIAEVGPGACGFAVGDRVALEPNITCGRCEYCRRGMTSACTSRLSAGVLTQPG 118
Query: 391 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
L H ++FC +L H+++E EPLAV A +R +
Sbjct: 119 FLAEVVDHPSEFCHRLDAHMSLERAVCAEPLAVAASAIRRTD 160
>UniRef50_Q9RKG0 Cluster: Putative dehydrogenase; n=1; Streptomyces
coelicolor|Rep: Putative dehydrogenase - Streptomyces
coelicolor
Length = 344
Score = 54.0 bits (124), Expect = 3e-06
Identities = 39/118 (33%), Positives = 55/118 (46%), Gaps = 2/118 (1%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVTRKPRQILQARSRFLLQAS*SR 449
G V EP + C+ C C+ G H+C + +F P Q + + L Q SR
Sbjct: 80 GALVVAEPLISCKDCRACREGHSHVCARLGLFGIDAP--GGAAQFVALPTSTLHQVP-SR 136
Query: 450 DHGRRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIID 620
++A P V G+ AG VV V GAGPIG+LT L A+ GA V++ +
Sbjct: 137 VEPTQAALTEPLAVAVHAVSRSGMEAGDVVAVFGAGPIGILTALVARHEGASHVVVAE 194
Score = 49.2 bits (112), Expect = 9e-05
Identities = 46/166 (27%), Positives = 74/166 (44%), Gaps = 4/166 (2%)
Frame = +1
Query: 28 TDNLTALLYKP-NDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP 204
T ++A+++ ND+R+ + P+PE+ L+R+ C GICG+D+ G+ H +
Sbjct: 2 TGGMSAVVWAGVNDVRVEEVPMPEVPPGWALVRVACTGICGTDLGI-VHGK--HPRARQG 58
Query: 205 MIMGHEASG---VVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPR 375
+I+GHE SG V A G LV+ P +C+ A
Sbjct: 59 LILGHEISGWVEVTAPGGPPEG--ALVVAEP-LISCKDCRACREGHSHVCARLGLFGIDA 115
Query: 376 PQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
P G ++ ++P V + AL EPLAV +HA R+
Sbjct: 116 P---GGAAQFVALPTSTLHQVPSRVEPTQAALTEPLAVAVHAVSRS 158
>UniRef50_Q92YT8 Cluster: Putative; n=2; Alphaproteobacteria|Rep:
Putative - Rhizobium meliloti (Sinorhizobium meliloti)
Length = 341
Score = 54.0 bits (124), Expect = 3e-06
Identities = 26/71 (36%), Positives = 43/71 (60%), Gaps = 1/71 (1%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMIMGH 219
A+L +P + + IPEI +VL+R+ GICG+D+H + GH+ + P++ GH
Sbjct: 4 AVLVEPRRFEVREVGIPEIGPADVLIRVTRAGICGTDLHIFN----GHYAADRLPIVPGH 59
Query: 220 EASGVVAKIGS 252
E G +A+IG+
Sbjct: 60 EFCGTIAEIGA 70
>UniRef50_Q0LSY1 Cluster: Alcohol dehydrogenase,
zinc-binding:Alcohol dehydrogenase GroES-like; n=2;
Alphaproteobacteria|Rep: Alcohol dehydrogenase,
zinc-binding:Alcohol dehydrogenase GroES-like -
Caulobacter sp. K31
Length = 364
Score = 54.0 bits (124), Expect = 3e-06
Identities = 39/138 (28%), Positives = 66/138 (47%), Gaps = 11/138 (7%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SR 449
VGDRVA+E + C C+ C GRYHLC D + P++ P + A ++++ A +
Sbjct: 84 VGDRVAVETMLSCHSCDTCLGGRYHLCADRQIYSYIPLSNMP-GLWGAYAQYMYLAPNTI 142
Query: 450 DH-------GRRSATGAPRGGHSR--VQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAH 602
H + P G R V+ G +++LG G GL +++ A+ GA
Sbjct: 143 VHKMDKTLPPELAVMFNPLGAGFRWAVEIPQTQVGDTIVILGPGQRGLASVIAARQAGAG 202
Query: 603 KVLIIDILQS--RLDFAK 650
K+++ + +LD A+
Sbjct: 203 KIIVTGMAADARKLDLAR 220
Score = 51.2 bits (117), Expect = 2e-05
Identities = 25/67 (37%), Positives = 36/67 (53%)
Frame = +1
Query: 58 PNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVV 237
P L + PIP+I D +LR++ GICGSD ++ G P+I GHE G++
Sbjct: 14 PRTLEMRDLPIPDIEADSAILRIEACGICGSDYEQFE----GVLKTPMPVIPGHEPVGII 69
Query: 238 AKIGSKS 258
IG K+
Sbjct: 70 EAIGDKA 76
>UniRef50_A5VBI0 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=1; Sphingomonas wittichii RW1|Rep: Alcohol
dehydrogenase, zinc-binding domain protein -
Sphingomonas wittichii RW1
Length = 337
Score = 54.0 bits (124), Expect = 3e-06
Identities = 44/156 (28%), Positives = 75/156 (48%)
Frame = +1
Query: 61 NDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 240
ND+R+ + P + +VL+R+ G+CGSD+ Y + G EP +GHE SG +
Sbjct: 10 NDVRIDEIADPMVGPRDVLVRVRRCGLCGSDLGYIKAGGVA-MPATEPFGIGHELSGTIE 68
Query: 241 KIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAA 420
+G++ R + +P +G + + P + AP ++ + HA
Sbjct: 69 AVGAEVRGIAPGLRVVVNP---MGDGNGIGAG----LPEGAFAPLLRVSNATLGGAIHA- 120
Query: 421 DFCFKLPDHVTMEEGALLEPLAVGIHACKRAESRRD 528
+PD V + AL EPLAV +HA +R+ + R+
Sbjct: 121 -----IPDPVGWDAAALAEPLAVALHAVRRSGATRE 151
>UniRef50_A1R5Y9 Cluster: L-threonine 3-dehydrogenase; n=1;
Arthrobacter aurescens TC1|Rep: L-threonine
3-dehydrogenase - Arthrobacter aurescens (strain TC1)
Length = 347
Score = 54.0 bits (124), Expect = 3e-06
Identities = 36/142 (25%), Positives = 61/142 (42%), Gaps = 1/142 (0%)
Frame = +1
Query: 91 PEISDDEVLLRMDCVGICGSDVHYWQKGQCGH-FVLEEPMIMGHEASGVVAKIGSKSRI* 267
P+ ++ V++ + +CG+D ++ F L P+++GHE +G V +IG
Sbjct: 22 PKATEGSVVIEVGAASLCGTDRELYEWTPSAQAFNLNLPVVLGHEGAGTVVEIGPGVTGL 81
Query: 268 QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADFCFKLPDH 447
++ + G R D + + G Y D C KLP
Sbjct: 82 KVGDQVALESHLTCGQCFPCRTGDAHTCER-TGILGMHIDGVFAEYAAVPQDICVKLPTG 140
Query: 448 VTMEEGALLEPLAVGIHACKRA 513
+++E GALLE V +HA +RA
Sbjct: 141 LSLESGALLEAAGVAVHAIQRA 162
Score = 44.4 bits (100), Expect = 0.002
Identities = 40/125 (32%), Positives = 56/125 (44%), Gaps = 3/125 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLC--PDMIFCATPPVTRKPRQILQARSRFL 428
V L VGD+VA+E + C C C+TG H C ++ V + + Q
Sbjct: 78 VTGLKVGDQVALESHLTCGQCFPCRTGDAHTCERTGILGMHIDGVFAEYAAVPQDIC-VK 136
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVS-AGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
L S + G A H+ +Q S AG VLV GAGP+GL+ + A GA
Sbjct: 137 LPTGLSLESG-ALLEAAGVAVHA-IQRANYSVAGRAVLVSGAGPVGLVVVNLALLMGASH 194
Query: 606 VLIID 620
V+ +D
Sbjct: 195 VIAVD 199
>UniRef50_UPI000038E1A4 Cluster: hypothetical protein Faci_03000847;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03000847 - Ferroplasma acidarmanus fer1
Length = 333
Score = 53.6 bits (123), Expect = 4e-06
Identities = 40/152 (26%), Positives = 64/152 (42%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 225
+L +P L L+ T + EV ++ GICG+D H + G+ H ++ P+I GHE
Sbjct: 5 VLKEPGVLELINTEARKPDTGEVQIKTRACGICGTDFHAY-NGK--HLAVKYPVIPGHEF 61
Query: 226 SGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRY 405
SGV+ IG + P G + + + G Y
Sbjct: 62 SGVITSIGEGVKSFMPGDRVVVDPNITCGQCEYCKGGKENFCENIKTV-GINYPGGYGEY 120
Query: 406 YKHAADFCFKLPDHVTMEEGALLEPLAVGIHA 501
+K+PD ++ E A++EP+A IHA
Sbjct: 121 VTVPEKVVYKIPDTMSFEAAAIVEPVACIIHA 152
Score = 41.9 bits (94), Expect = 0.013
Identities = 14/35 (40%), Positives = 23/35 (65%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM 359
VK+ GDRV ++P + C CE+CK G+ + C ++
Sbjct: 72 VKSFMPGDRVVVDPNITCGQCEYCKGGKENFCENI 106
>UniRef50_Q8DIZ5 Cluster: Sorbitol dehydrogenase; n=6;
Cyanobacteria|Rep: Sorbitol dehydrogenase -
Synechococcus elongatus (Thermosynechococcus elongatus)
Length = 366
Score = 53.6 bits (123), Expect = 4e-06
Identities = 30/82 (36%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
Frame = +1
Query: 7 FRASDMATDNLTALLYKP-NDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCG 183
FR A ++ A +++ N L + PIPEI+ DEVL+R+ VG+C SD+ +
Sbjct: 7 FRGDAFAKVSMKAQVFRGVNQLSYEEIPIPEIAADEVLVRVRVVGLCQSDIK-----KIR 61
Query: 184 HFVLEEPMIMGHEASGVVAKIG 249
+ + E P I GHE +G +A +G
Sbjct: 62 YPLYEPPRIFGHETAGEIAAVG 83
Score = 45.6 bits (103), Expect = 0.001
Identities = 21/52 (40%), Positives = 34/52 (65%)
Frame = +3
Query: 501 VQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
V++ G++ G VL+ GAGPIGL+ ++ FGA + + D+L SR+ AK +
Sbjct: 177 VKKAGIAPGQTVLITGAGPIGLMFIMLVNLFGA-RAIATDLLPSRIAKAKEV 227
>UniRef50_Q83GG5 Cluster: Zinc-type alcohol dehydrogenase; n=3;
Actinomycetales|Rep: Zinc-type alcohol dehydrogenase -
Tropheryma whipplei (strain Twist) (Whipple's bacillus)
Length = 357
Score = 53.6 bits (123), Expect = 4e-06
Identities = 48/178 (26%), Positives = 73/178 (41%), Gaps = 13/178 (7%)
Frame = +3
Query: 162 LAEGSMRTLRAGRTNDH-GTRSFRSSGQDRFEVKNLTVGDRVAIEPGVPCRYCEFCKTGR 338
+ +G + ++ G H G G+D VK+ +VGDRV + P C C FC+
Sbjct: 47 ILKGDVAAVKPGTVLGHEGIGKIVEVGKD---VKSHSVGDRVIVSPMSSCGVCRFCRANN 103
Query: 339 YHLC------------PDMIFCATPPVTRKPRQILQARSRFLLQAS*SRDHGRRSATGAP 482
C +I R P L S L + G + P
Sbjct: 104 NGHCLGDSEGPGGWRLGGLINGVQAQFARIP---LADNSLHKLPSGLDPKVGILVSDVLP 160
Query: 483 RGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
G Q G V+ G VV V+G GP+GL ++T+ + KV+ +D +RL+ A+ L
Sbjct: 161 TGHEVGAQAGQVTLGSVVAVIGCGPVGLGAIVTSLLYSPSKVIAVDADSNRLELARKL 218
Score = 34.7 bits (76), Expect = 2.0
Identities = 20/61 (32%), Positives = 32/61 (52%)
Frame = +1
Query: 67 LRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 246
L V P ++ D V+L M+ ICGSD+H KG ++ ++GHE G + ++
Sbjct: 17 LDTVDDPTIKLGTD-VILEMETTTICGSDLHI-LKGDVA--AVKPGTVLGHEGIGKIVEV 72
Query: 247 G 249
G
Sbjct: 73 G 73
>UniRef50_Q2RG84 Cluster: Alcohol dehydrogenase superfamily,
zinc-containing; n=1; Moorella thermoacetica ATCC
39073|Rep: Alcohol dehydrogenase superfamily,
zinc-containing - Moorella thermoacetica (strain ATCC
39073)
Length = 358
Score = 53.6 bits (123), Expect = 4e-06
Identities = 30/77 (38%), Positives = 43/77 (55%), Gaps = 1/77 (1%)
Frame = +1
Query: 22 MATDNLTAL-LYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLE 198
M + + AL L+ PND+RLV+ P+P+ EVL+R+ GICG+DV KG
Sbjct: 4 MIPEKMKALVLFGPNDVRLVEKPVPKPGPGEVLVRVAACGICGTDVKIITKGMPKMPPYG 63
Query: 199 EPMIMGHEASGVVAKIG 249
E GHE +G + +G
Sbjct: 64 E-FTFGHEWAGTIVALG 79
Score = 43.2 bits (97), Expect = 0.006
Identities = 19/45 (42%), Positives = 29/45 (64%)
Frame = +3
Query: 504 QEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRL 638
+ GG AG VLV+G GPIGL + A++ GA K++++ + RL
Sbjct: 172 KSGGYIAGDTVLVIGPGPIGLSVVQGARSLGAEKIILMGTREDRL 216
Score = 34.3 bits (75), Expect = 2.6
Identities = 16/32 (50%), Positives = 17/32 (53%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLC 350
V VGDRVAIE C CE C G+Y C
Sbjct: 82 VDEFQVGDRVAIEAHKGCGRCENCIDGKYTAC 113
>UniRef50_Q44P31 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=3; Chlorobiaceae|Rep: Zinc-containing
alcohol dehydrogenase superfamily - Chlorobium limicola
DSM 245
Length = 421
Score = 53.6 bits (123), Expect = 4e-06
Identities = 45/161 (27%), Positives = 65/161 (40%), Gaps = 2/161 (1%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 225
+L +P L L + PE +DE L+R+ C +C +D WQ GH L P ++GHE
Sbjct: 106 VLKEPRSLGLCERNDPETGEDEALVRVVCCSVCRTDAKMWQS---GHRDLVMPRVLGHEI 162
Query: 226 SGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLH--GNLV 399
SG + + V WP +C +++ +S H G
Sbjct: 163 SGYLDN--------ERVAVWP-GISCGSCAFCLAGRENLC-----ASMQILGFHHDGGFA 208
Query: 400 RYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESR 522
Y +PD + ME AL EPL +H RA R
Sbjct: 209 EYVAVRRTSLLSVPDTLPMELAALAEPLGCALHGLDRAGVR 249
Score = 50.8 bits (116), Expect = 3e-05
Identities = 38/122 (31%), Positives = 52/122 (42%), Gaps = 1/122 (0%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLL 431
E+ +RVA+ PG+ C C FC GR +LC M + + R LL
Sbjct: 161 EISGYLDNERVAVWPGISCGSCAFCLAGRENLCASMQILGFHH-DGGFAEYVAVRRTSLL 219
Query: 432 QAS*SRDHGRRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
+ +A P G + GV +G VL+ GAG +GL L A GAH V
Sbjct: 220 SVPDTLPM-ELAALAEPLGCALHGLDRAGVRSGERVLIYGAGSLGLFLALGAAERGAHPV 278
Query: 609 LI 614
+I
Sbjct: 279 VI 280
>UniRef50_A5WI29 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=18; Bacteria|Rep: Alcohol dehydrogenase,
zinc-binding domain protein - Psychrobacter sp. PRwf-1
Length = 354
Score = 53.6 bits (123), Expect = 4e-06
Identities = 48/173 (27%), Positives = 77/173 (44%), Gaps = 12/173 (6%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKG-----QCGH----FVL 195
A Y D+R+ P P + V +++ GICG+D+H + +G CGH
Sbjct: 4 ARFYDKGDIRIEDIPEPTVKPGTVGIKVAWCGICGTDLHEFMEGPIFIPPCGHPHPISGE 63
Query: 196 EEPMIMGHEASGVVAKIG---SKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SS 366
P+ MGHE SGVV +G + I Q V+ P A V T D+ + +
Sbjct: 64 SAPVTMGHEFSGVVYAVGEGVNDIEIGQHVVVEPYIVADDVPTGPG---DNYHLSKDMNF 120
Query: 367 APRPQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESRR 525
G L + + + + +++ AL+EPLAVG HA R+ +++
Sbjct: 121 IGLGGRGGGLSEKIAVERRWVHPISNKIPLDQAALIEPLAVGYHAFIRSGAQK 173
Score = 37.1 bits (82), Expect = 0.37
Identities = 32/132 (24%), Positives = 51/132 (38%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V ++ +G V +EP + YHL DM F + + R++
Sbjct: 84 VNDIEIGQHVVVEPYIVADDVPTGPGDNYHLSKDMNFIGLGGRGGGLSEKIAVERRWVHP 143
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
S + + G+ G G + LV G GPIGLL KA G V++
Sbjct: 144 ISNKIPLDQAALIEPLAVGYHAFIRSGAQKGDIALVGGGGPIGLLLSAVLKAKGI-TVIM 202
Query: 615 IDILQSRLDFAK 650
++ + R + AK
Sbjct: 203 TELSEKRKEKAK 214
>UniRef50_A1UQB9 Cluster: Alcohol dehydrogenase GroES domain
protein; n=9; Actinomycetales|Rep: Alcohol dehydrogenase
GroES domain protein - Mycobacterium sp. (strain KMS)
Length = 343
Score = 53.6 bits (123), Expect = 4e-06
Identities = 41/157 (26%), Positives = 69/157 (43%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A+ + D+R+ + P P EV++ + GICG+D+H + G H +++GHE
Sbjct: 4 AIYHGREDVRIEELPDPSPRAGEVVIEVARAGICGTDLHEYIAGPM-H--AAPGVVIGHE 60
Query: 223 ASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVR 402
SG V +GS R G +Q ++G L R
Sbjct: 61 YSGTVVGVGSGVREFTEGDRVCGVGVFGCGECGFCKQGAEALCGAVGFIGF-AVNGALAR 119
Query: 403 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
Y F++PD +++ E A++EP+A HA +R+
Sbjct: 120 YASLPTKALFRIPDEISLAEAAVVEPIASAYHAVRRS 156
Score = 47.2 bits (107), Expect = 3e-04
Identities = 34/127 (26%), Positives = 54/127 (42%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V+ T GDRV C C FCK G LC + F V + ++ L +
Sbjct: 72 VREFTEGDRVCGVGVFGCGECGFCKQGAEALCGAVGFIGFA-VNGALARYASLPTKALFR 130
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
+ + V+ G++AG V + GAGPIGL + + A GA +V++
Sbjct: 131 IPDEISLAEAAVVEPIASAYHAVRRSGLAAGGTVFIAGAGPIGLALVQFSLAKGATQVIV 190
Query: 615 IDILQSR 635
++ +R
Sbjct: 191 NEVSATR 197
>UniRef50_Q8Y414 Cluster: Lmo2663 protein; n=14; Firmicutes|Rep:
Lmo2663 protein - Listeria monocytogenes
Length = 343
Score = 53.2 bits (122), Expect = 5e-06
Identities = 38/150 (25%), Positives = 69/150 (46%), Gaps = 3/150 (2%)
Frame = +1
Query: 61 NDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 240
+ + L P++ D+V +++ GICGSD+H + KG+ + P+ +GHE SGVV
Sbjct: 12 DQMELKDVEEPQVYGDKVKIKVAFTGICGSDIHTF-KGEYKN--PTTPVTLGHEFSGVVV 68
Query: 241 KIG---SKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYK 411
++G + ++ V C G ++ D Q +G+ +
Sbjct: 69 EVGPDVTSIKVGDRVTSETTFETC--GECIYCKEHDYNLCSN-RRGIGTQANGSFAEFVL 125
Query: 412 HAADFCFKLPDHVTMEEGALLEPLAVGIHA 501
+ C L + +++E AL EPLA +H+
Sbjct: 126 SREESCHVLDERISLEAAALTEPLACCVHS 155
Score = 41.5 bits (93), Expect = 0.017
Identities = 42/138 (30%), Positives = 59/138 (42%), Gaps = 3/138 (2%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVP-CRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQIL-QARSRF 425
+V ++ VGDRV E C C +CK Y+LC + T +L + S
Sbjct: 73 DVTSIKVGDRVTSETTFETCGECIYCKEHDYNLCSNRRGIGTQANGSFAEFVLSREESCH 132
Query: 426 LLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
+L S + + A HS +++ + VLV G GPIGLL KA GA
Sbjct: 133 VLDERISLEAAALTEPLACCV-HSALEKTTIRPDDTVLVFGPGPIGLLLAQVVKAQGATV 191
Query: 606 VLI-IDILQSRLDFAKSL 656
++ I RL AK L
Sbjct: 192 IMAGITKDSDRLRLAKEL 209
>UniRef50_Q829Q5 Cluster: Putative zinc-binding dehydrogenase; n=2;
Streptomyces|Rep: Putative zinc-binding dehydrogenase -
Streptomyces avermitilis
Length = 329
Score = 53.2 bits (122), Expect = 5e-06
Identities = 38/137 (27%), Positives = 63/137 (45%), Gaps = 2/137 (1%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQ--ARSRF 425
+V ++VGDRVA++P + C C +C+TG +LC R + A
Sbjct: 70 QVTEVSVGDRVAVDPSLYCYECRYCRTGHNNLCERWAAIGVTTAGGAARYAVAPVANCVK 129
Query: 426 LLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
L + ++D G+ ++ G VLV G+G +GL+ + AK GA
Sbjct: 130 LPEHVRTQDAALIEPLSCAVRGYDVLRS---RLGAHVLVYGSGTMGLMMLELAKRTGAAS 186
Query: 606 VLIIDILQSRLDFAKSL 656
V ++D+ +RL A+ L
Sbjct: 187 VDVVDVNPARLTTARQL 203
Score = 51.6 bits (118), Expect = 2e-05
Identities = 38/150 (25%), Positives = 62/150 (41%)
Frame = +1
Query: 73 LVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 252
+ + P P EV++ + G+CG+D+H Q G F + P++ GHE +G V +G+
Sbjct: 14 VAEVPDPTPGPREVVVEVAACGLCGTDLHILQ----GEFAPKLPIVPGHEFAGEVVGLGT 69
Query: 253 KSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADFCF 432
+ + P+ R +A G RY C
Sbjct: 70 QVTEVSVGDRVAVDPSLYCYECRYCRTGHNNLCER-WAAIGVTTAGGAARYAVAPVANCV 128
Query: 433 KLPDHVTMEEGALLEPLAVGIHACKRAESR 522
KLP+HV ++ AL+EPL+ + SR
Sbjct: 129 KLPEHVRTQDAALIEPLSCAVRGYDVLRSR 158
>UniRef50_Q1IQV6 Cluster: Alcohol dehydrogenase GroES-like; n=2;
Acidobacteria|Rep: Alcohol dehydrogenase GroES-like -
Acidobacteria bacterium (strain Ellin345)
Length = 374
Score = 53.2 bits (122), Expect = 5e-06
Identities = 29/69 (42%), Positives = 39/69 (56%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A+ + ND+RL P+PEI EVL+R+ GICG+D+ G H P I GHE
Sbjct: 22 AVYHGLNDVRLETVPVPEIGRGEVLIRVASCGICGTDLKKISTG--SH---SAPRIFGHE 76
Query: 223 ASGVVAKIG 249
+GV+A G
Sbjct: 77 TAGVIAAAG 85
Score = 32.7 bits (71), Expect = 8.0
Identities = 17/52 (32%), Positives = 28/52 (53%)
Frame = +3
Query: 501 VQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
++ + +G VLV+G G IG++ A+ GA V+ D+ RL +SL
Sbjct: 179 IETMALKSGETVLVIGQGAIGMILAFLAQRAGA-TVITSDLFPQRLTIGESL 229
>UniRef50_A4XGJ9 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=1; Caldicellulosiruptor saccharolyticus DSM
8903|Rep: Alcohol dehydrogenase, zinc-binding domain
protein - Caldicellulosiruptor saccharolyticus (strain
ATCC 43494 / DSM 8903)
Length = 344
Score = 53.2 bits (122), Expect = 5e-06
Identities = 38/135 (28%), Positives = 61/135 (45%), Gaps = 1/135 (0%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V N+ GDRVAI V C C +CK+G +C C + + + + ++
Sbjct: 80 VTNVKPGDRVAIYLAVSCGECLYCKSGYKMMCKQFK-CIGFDLHGGDAEYMVVPAENCMK 138
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEG-GVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVL 611
+ + + G Q+ G+S +V + G GP+G +L AK GA V+
Sbjct: 139 IPDEMSYITAAVSTDAIGTLYHAQKRMGISGRDIVAIYGIGPMGAAGILVAKGLGA-TVI 197
Query: 612 IIDILQSRLDFAKSL 656
+D + RLD+AK L
Sbjct: 198 AVDTIDKRLDWAKEL 212
Score = 37.5 bits (83), Expect = 0.28
Identities = 39/152 (25%), Positives = 60/152 (39%), Gaps = 10/152 (6%)
Frame = +1
Query: 85 PIPEISDDEVLLRMDCVGICGSD--VHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKS 258
PIP+ D EVL+++ IC SD ++Y G +I GHE +G + ++G
Sbjct: 21 PIPKPKDGEVLVKIKASAICRSDMSLYYGNPVVGGEIAKSGSIIPGHEPAGEIVEVGKGV 80
Query: 259 RI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQ-------LHGNLVRYYKHA 417
P RV +V + Y + Q LHG Y
Sbjct: 81 T--------NVKPGDRVAIYLAVSCGECLYCKSGYKMMCKQFKCIGFDLHGGDAEYMVVP 132
Query: 418 ADFCFKLPDHVTMEEGAL-LEPLAVGIHACKR 510
A+ C K+PD ++ A+ + + HA KR
Sbjct: 133 AENCMKIPDEMSYITAAVSTDAIGTLYHAQKR 164
>UniRef50_Q98CF7 Cluster: 2,3-butanediol dehydrogenase; n=5;
Rhizobiales|Rep: 2,3-butanediol dehydrogenase -
Rhizobium loti (Mesorhizobium loti)
Length = 289
Score = 52.8 bits (121), Expect = 7e-06
Identities = 44/137 (32%), Positives = 59/137 (43%), Gaps = 3/137 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQ-ILQARSRFLL 431
V VGDRV +P + C C C GR +LC ++ +L + F+L
Sbjct: 18 VSGFAVGDRVTGDPNIACGRCPHCHAGRVNLCRNLNAIGIHRDGGFAEYVVLPQKQAFIL 77
Query: 432 QAS*SRDHGRRSATGAPRGG--HSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
A HG A P G H V + G V+VLG G IGLLT+ AK GA
Sbjct: 78 PADLPPTHG---AFCEPLGCCLHG-VDLAQIKPGSSVVVLGGGVIGLLTVQLAKLAGATT 133
Query: 606 VLIIDILQSRLDFAKSL 656
+++ SR A+ L
Sbjct: 134 IILSTRQASRRVLAEEL 150
>UniRef50_Q39TG2 Cluster: Alcohol dehydrogenase superfamily,
zinc-containing; n=1; Geobacter metallireducens
GS-15|Rep: Alcohol dehydrogenase superfamily,
zinc-containing - Geobacter metallireducens (strain
GS-15 / ATCC 53774 / DSM 7210)
Length = 340
Score = 52.8 bits (121), Expect = 7e-06
Identities = 43/158 (27%), Positives = 73/158 (46%), Gaps = 7/158 (4%)
Frame = +1
Query: 55 KPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 234
KP + + PIP D EV++ + GICG+D+H + L + ++GHE +G
Sbjct: 11 KPLAIESLNDPIP--LDGEVIVNVKACGICGTDIHATADKE---MRLADGTVLGHEFAGE 65
Query: 235 VAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDD----TTYAPT*SSAPRP---QLHGN 393
+ ++G Q+ + W + R+ T + T P + Q G
Sbjct: 66 IVEVGP-----QVAVGW--AQGDRLCTLPYIGCGHCLACLTGMPWQCKLKKVIGIQTAGG 118
Query: 394 LVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACK 507
Y + + +LP V+ +EGAL+EPLA+G+HA +
Sbjct: 119 FAEYARVHVNEAVRLPVSVSWQEGALVEPLAIGLHAVR 156
Score = 39.9 bits (89), Expect = 0.053
Identities = 40/130 (30%), Positives = 55/130 (42%), Gaps = 2/130 (1%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCP--DMIFCATPPVTRKPRQILQARSRFLLQAS*S 446
GDR+ P + C +C C TG C +I T + ++ L S S
Sbjct: 80 GDRLCTLPYIGCGHCLACLTGMPWQCKLKKVIGIQTAGGFAEYARV-HVNEAVRLPVSVS 138
Query: 447 RDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDIL 626
G A G H+ GV AG VLV GAGPIGL L + FGA +V++ +
Sbjct: 139 WQEGALVEPLAI-GLHAVRLSRGV-AGKSVLVTGAGPIGLAVALWCRFFGARQVVVSEFD 196
Query: 627 QSRLDFAKSL 656
R A ++
Sbjct: 197 PERSKMALAM 206
>UniRef50_A0NL69 Cluster: Sorbitol dehydrogenase; n=2; Oenococcus
oeni|Rep: Sorbitol dehydrogenase - Oenococcus oeni ATCC
BAA-1163
Length = 358
Score = 52.8 bits (121), Expect = 7e-06
Identities = 23/73 (31%), Positives = 44/73 (60%)
Frame = +1
Query: 31 DNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 210
D A+L + + + P+PEI+DDE+L++++ G+CG+DV ++ + P+
Sbjct: 15 DGKVAVLTGTKKIEVKKLPVPEINDDEMLVKVEGCGVCGTDVFEYKSDPFNYI----PVN 70
Query: 211 MGHEASGVVAKIG 249
+GHE +G + K+G
Sbjct: 71 LGHEGTGEIVKMG 83
Score = 36.7 bits (81), Expect = 0.49
Identities = 16/41 (39%), Positives = 24/41 (58%)
Frame = +3
Query: 534 VLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
V+V G GPIGL+ + K G ++ +D SRL+ AK +
Sbjct: 177 VVVQGVGPIGLMVIAQMKTLGVRHIIAVDGNASRLELAKKI 217
>UniRef50_A0LL41 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
Alcohol dehydrogenase GroES domain protein -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 338
Score = 52.8 bits (121), Expect = 7e-06
Identities = 43/137 (31%), Positives = 62/137 (45%), Gaps = 3/137 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTR--KPRQILQARSRFL 428
V VG+RV P VPC C +C+ G Y C ++ +IL + +
Sbjct: 69 VTGFKVGERVFAVPKVPCMECHYCRNGHYPQCAEIKVRLPGGFAEYILVPEILVEKGTYH 128
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQE-GGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
L + + D +S P R Q G+ AG V+VLG G GLL + AKA +
Sbjct: 129 LPDTITYD---QSTFIEPLACVVRAQRLAGIRAGQTVVVLGCGMSGLLHVKLAKARDC-R 184
Query: 606 VLIIDILQSRLDFAKSL 656
V+ D+ + RL FA+ L
Sbjct: 185 VVAADVNRKRLAFAEQL 201
Score = 44.8 bits (101), Expect = 0.002
Identities = 22/64 (34%), Positives = 33/64 (51%)
Frame = +1
Query: 61 NDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 240
ND+R+ + P E+LL++ GICGSDV W + P++ GHE V
Sbjct: 10 NDIRIEEVATPRPGPKEMLLKVASCGICGSDVVEWYRKP------RAPLVQGHEIGAEVV 63
Query: 241 KIGS 252
++GS
Sbjct: 64 EVGS 67
>UniRef50_A0JVW4 Cluster: Alcohol dehydrogenase GroES domain
protein; n=2; Arthrobacter|Rep: Alcohol dehydrogenase
GroES domain protein - Arthrobacter sp. (strain FB24)
Length = 343
Score = 52.8 bits (121), Expect = 7e-06
Identities = 37/132 (28%), Positives = 59/132 (44%), Gaps = 1/132 (0%)
Frame = +3
Query: 264 LTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS* 443
+ G RVA+ P +PC C C G H+C ++ V ++L L S
Sbjct: 83 IPAGTRVAVNPLLPCGQCGACLKGLGHVCRNLRLLGID-VPGSMTEVLAVPVSNLFAFS- 140
Query: 444 SRDHGRRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIID 620
+ +A P V+ ++ G VL+ GAGPIG+L L A+ GA VL+++
Sbjct: 141 ADAPATEAALAEPLAVAVHAVRRSRLAPGEKVLIFGAGPIGILVALVARFRGAKDVLLVE 200
Query: 621 ILQSRLDFAKSL 656
+ R ++L
Sbjct: 201 PSEQRRHIVEAL 212
Score = 34.3 bits (75), Expect = 2.6
Identities = 22/79 (27%), Positives = 37/79 (46%)
Frame = +1
Query: 13 ASDMATDNLTALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFV 192
++ + T A+L + + P P L+R+ GICGSD G+ H
Sbjct: 4 STTLTTGIRAAVLSAAHHFEVQHVPKPSPGPGAALVRVSYTGICGSDFPI-VDGR--HPR 60
Query: 193 LEEPMIMGHEASGVVAKIG 249
P+I+GHE +G++ + G
Sbjct: 61 AAMPLILGHEITGILEEPG 79
>UniRef50_A1DNE9 Cluster: Alcohol dehydrogenase; n=4;
Trichocomaceae|Rep: Alcohol dehydrogenase - Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 375
Score = 52.8 bits (121), Expect = 7e-06
Identities = 42/155 (27%), Positives = 65/155 (41%), Gaps = 7/155 (4%)
Frame = +1
Query: 58 PNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQC-----GHFV--LEEPMIMG 216
P D+R+ + P +V LR VGICGSD+H + G H + P+ +G
Sbjct: 30 PGDIRIEEIDEPTCGKGQVKLRPAFVGICGSDLHEYSAGPVLIPKEPHKITGTSYPVTLG 89
Query: 217 HEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNL 396
HE +G+V ++G P S + G +
Sbjct: 90 HEFAGIVEEVGEGVTHLSPGQRAVVRPTIFDRQCCSCKLGYEYCCENIGFIGLSGYGGGM 149
Query: 397 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHA 501
++ A+ + LPD+V++E AL+EPLAV HA
Sbjct: 150 AKHTVAPAEHFYPLPDNVSLEAAALIEPLAVAWHA 184
Score = 36.3 bits (80), Expect = 0.65
Identities = 33/133 (24%), Positives = 55/133 (41%), Gaps = 2/133 (1%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVT--RKPRQILQARSRFL 428
V +L+ G R + P + R C CK G + C ++ F + A +
Sbjct: 103 VTHLSPGQRAVVRPTIFDRQCCSCKLGYEYCCENIGFIGLSGYGGGMAKHTVAPAEHFYP 162
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
L + S + A H+ V G V+V+G GPIG+ + K GA K+
Sbjct: 163 LPDNVSLEAAALIEPLAV-AWHA-VNLSPFKGGDNVMVVGGGPIGIGIVQILKLQGAKKI 220
Query: 609 LIIDILQSRLDFA 647
++ ++L +R A
Sbjct: 221 MVAELLDNRKKLA 233
>UniRef50_Q46N56 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=2; Burkholderiales|Rep: Zinc-containing
alcohol dehydrogenase superfamily - Ralstonia eutropha
(strain JMP134) (Alcaligenes eutrophus)
Length = 337
Score = 52.4 bits (120), Expect = 9e-06
Identities = 40/157 (25%), Positives = 69/157 (43%), Gaps = 2/157 (1%)
Frame = +1
Query: 37 LTALLY-KPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP-MI 210
+ A++Y +P+ + ++ +P++ E+LLR+D GICGSD+H + GH +P ++
Sbjct: 1 MKAIVYTQPDAVEVLDRDMPDLEPGEILLRIDASGICGSDLHAYH----GHDPRRKPGLV 56
Query: 211 MGHEASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHG 390
+GHE +G V ++R+ + +P G Q + G
Sbjct: 57 LGHEFAGTVIASSDEARM-PVGQRVTANPLVTCGHCDYCLQGRDNLCANRGMVGMNR-PG 114
Query: 391 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHA 501
L Y +PD + AL EP A +HA
Sbjct: 115 ALSEYLAIPIRCAIPIPDTLPSVSAALTEPAATALHA 151
Score = 34.7 bits (76), Expect = 2.0
Identities = 13/29 (44%), Positives = 18/29 (62%)
Frame = +3
Query: 264 LTVGDRVAIEPGVPCRYCEFCKTGRYHLC 350
+ VG RV P V C +C++C GR +LC
Sbjct: 74 MPVGQRVTANPLVTCGHCDYCLQGRDNLC 102
>UniRef50_A7B0E7 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus gnavus ATCC 29149|Rep: Putative
uncharacterized protein - Ruminococcus gnavus ATCC 29149
Length = 406
Score = 52.4 bits (120), Expect = 9e-06
Identities = 22/74 (29%), Positives = 44/74 (59%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A+L + + + P+PE+ D ++L++++ GICG+D H ++K G P+ +GHE
Sbjct: 47 AMLTALENYEVKEFPMPEVGDGDILVKVEGCGICGTDAHEFKKDPFGLI----PVALGHE 102
Query: 223 ASGVVAKIGSKSRI 264
+G + K+G ++
Sbjct: 103 GTGEIVKMGKNVKV 116
Score = 39.9 bits (89), Expect = 0.053
Identities = 17/41 (41%), Positives = 25/41 (60%)
Frame = +3
Query: 534 VLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
V+V G GPIGL+ + + G ++ +D Q RLDFAK +
Sbjct: 222 VVVQGCGPIGLICIAVLRTMGIENIVAVDGEQKRLDFAKKM 262
>UniRef50_A5D4M1 Cluster: Zn-dependent alcohol dehydrogenases; n=1;
Pelotomaculum thermopropionicum SI|Rep: Zn-dependent
alcohol dehydrogenases - Pelotomaculum thermopropionicum
SI
Length = 372
Score = 52.4 bits (120), Expect = 9e-06
Identities = 43/136 (31%), Positives = 66/136 (48%), Gaps = 7/136 (5%)
Frame = +3
Query: 261 NLTVGDRVAIEPGVPCRYCEFCKTGRYHLC------PDMIFCATPPVTRKPRQILQARSR 422
+L+ G RVA+ P C C FCK GR++LC I R PR+I+
Sbjct: 98 DLSPGKRVAVYPIAVCGECFFCKRGRHNLCLREYGLAHGIDGGFAQYVRIPREIVAIGGL 157
Query: 423 FLLQAS*SRDHGRRSATGAPRGGH-SRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGA 599
L S + ++A P + + G + G +LV+GAGP+GLL + T GA
Sbjct: 158 VELPEHLSYE---QAAMAEPLSCCLAAARAGKLEEGDTMLVVGAGPMGLLHLKTGLWRGA 214
Query: 600 HKVLIIDILQSRLDFA 647
+V++ D+ + RL+ A
Sbjct: 215 -RVIVADLRRDRLEMA 229
Score = 47.2 bits (107), Expect = 3e-04
Identities = 24/70 (34%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMIMGH 219
A+++ D+R+ P+PE EVL+++ GIC +D+ K G + E+ P I+GH
Sbjct: 27 AVVHGKGDIRIEPVPVPETGYGEVLVKVRASGICATDI----KTLLGQGLPEKLPAILGH 82
Query: 220 EASGVVAKIG 249
E +G V ++G
Sbjct: 83 EVAGTVERVG 92
>UniRef50_UPI00015BC9A2 Cluster: UPI00015BC9A2 related cluster; n=1;
unknown|Rep: UPI00015BC9A2 UniRef100 entry - unknown
Length = 335
Score = 52.0 bits (119), Expect = 1e-05
Identities = 26/56 (46%), Positives = 37/56 (66%)
Frame = +1
Query: 85 PIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 252
PIPEI DEVL+++ GIC SD+H G +V + P++ GHE +G+V K+GS
Sbjct: 19 PIPEIGPDEVLIKVKYCGICHSDLHI-VDGDWESWV-KLPVVPGHEVAGIVEKVGS 72
>UniRef50_Q7US13 Cluster: Probable zinc-type alcohol dehydrogenase;
n=3; Bacteria|Rep: Probable zinc-type alcohol
dehydrogenase - Rhodopirellula baltica
Length = 396
Score = 52.0 bits (119), Expect = 1e-05
Identities = 22/66 (33%), Positives = 38/66 (57%)
Frame = +1
Query: 55 KPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 234
+P + + + PEI +VLL + VG+CGSD+H W + + P+++GHE G
Sbjct: 66 EPGSVEIREIDRPEIGSQDVLLEVSHVGVCGSDLHQWTAHH--SWPVNYPVVLGHEFGGH 123
Query: 235 VAKIGS 252
+ ++GS
Sbjct: 124 IVQLGS 129
>UniRef50_Q0RVL1 Cluster: Zn-dependent alcohol dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Zn-dependent alcohol
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 347
Score = 52.0 bits (119), Expect = 1e-05
Identities = 27/73 (36%), Positives = 39/73 (53%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A+ +P + + P P+ +VLLR VGICGSD+H ++KG G IMGHE
Sbjct: 4 AVYQRPGLIEVQDVPTPQPGPRDVLLRTRAVGICGSDLHVYRKGLYG---ATTGWIMGHE 60
Query: 223 ASGVVAKIGSKSR 261
G ++G + R
Sbjct: 61 FCGEAVEVGEEVR 73
>UniRef50_A6NT70 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 351
Score = 52.0 bits (119), Expect = 1e-05
Identities = 40/136 (29%), Positives = 60/136 (44%), Gaps = 4/136 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPD---MIFCATPPV-TRKPRQILQARSR 422
VK + G RVA C C FCK G + C + C T R
Sbjct: 77 VKKIKPGQRVAANVETFCGECWFCKQGFVNNCVQGGWELGCRIDGCQTEYVRVPFADNGL 136
Query: 423 FLLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAH 602
++ S + + + P G+ + + G V+VLGAGP+G TM++A+ FG
Sbjct: 137 TVIPDSLAYEDVIMLSCILP-SGYFGAELAEIKPGDTVVVLGAGPVGCTTMMSARLFGPA 195
Query: 603 KVLIIDILQSRLDFAK 650
++ +D + RLDFAK
Sbjct: 196 CIVAVDPIGERLDFAK 211
Score = 37.5 bits (83), Expect = 0.28
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 1/77 (1%)
Frame = +1
Query: 22 MATDNLTALLYKPNDLRLVQTPIPEISDD-EVLLRMDCVGICGSDVHYWQKGQCGHFVLE 198
M+ + + + DLR + PIP I D + ++++ IC SD H + G
Sbjct: 1 MSGTMMAVVYHGKGDLRFEERPIPTILDSRDAIVKVGMSSICTSDFHI-RNGAVPR--AR 57
Query: 199 EPMIMGHEASGVVAKIG 249
E +I+GHE +G V +G
Sbjct: 58 ENVILGHEFAGEVVAVG 74
>UniRef50_P14940 Cluster: Alcohol dehydrogenase; n=31; cellular
organisms|Rep: Alcohol dehydrogenase - Ralstonia
eutropha (Alcaligenes eutrophus)
Length = 366
Score = 52.0 bits (119), Expect = 1e-05
Identities = 23/70 (32%), Positives = 41/70 (58%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A+ +P + L PIP+I ++ L+R+ ICG+DVH + G + + + + +GHE
Sbjct: 8 AVFVEPGRIELADKPIPDIGPNDALVRITTTTICGTDVHILK----GEYPVAKGLTVGHE 63
Query: 223 ASGVVAKIGS 252
G++ K+GS
Sbjct: 64 PVGIIEKLGS 73
Score = 37.5 bits (83), Expect = 0.28
Identities = 18/56 (32%), Positives = 26/56 (46%)
Frame = +3
Query: 489 GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
G + + GH V V GPIGL A+ GA ++ ID RL+ A+ +
Sbjct: 172 GFKGAENANIRIGHTVAVFAQGPIGLCATAGARLCGATTIIAIDGNDHRLEIARKM 227
>UniRef50_UPI0000553E21 Cluster: Zinc-containing alcohol
dehydrogenase superfamily; n=1; Paracoccus denitrificans
PD1222|Rep: Zinc-containing alcohol dehydrogenase
superfamily - Paracoccus denitrificans PD1222
Length = 237
Score = 51.6 bits (118), Expect = 2e-05
Identities = 25/52 (48%), Positives = 33/52 (63%)
Frame = +3
Query: 501 VQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
V GGV G VLV GAGPIGLL +L A+A GA ++ + D RL+ A+ +
Sbjct: 164 VDRGGVKPGDAVLVTGAGPIGLLALLAARAAGAVQLFVSDPNAKRLEIARDI 215
Score = 45.2 bits (102), Expect = 0.001
Identities = 42/158 (26%), Positives = 68/158 (43%), Gaps = 9/158 (5%)
Frame = +1
Query: 64 DLRLVQTPIP-EISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-------PMIMGH 219
DLR+ P P E + DEV++ GICG+D+H + G FV ++ ++GH
Sbjct: 11 DLRVEDIPQPTEPAADEVVIENRFAGICGTDLHEYAYGPI--FVPKDAATGAVAAQVLGH 68
Query: 220 EASGVVAKIGSKSRI*QLVIEWP*SPACRV-GTASSVRQDDTTYAPT*SSAPRPQLHGNL 396
E G V K+G ++ P G + + + A + G +
Sbjct: 69 EYGGTVVKVGRDVTHVKVGDRVSVQPFITPRGGDYYTDRGQFNLSDAMALAGLSWIGGGM 128
Query: 397 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKR 510
+KLPD +T E+ AL+EP+AV ++ R
Sbjct: 129 AESSLLKGYNVYKLPDQMTDEDAALVEPVAVAVYGVDR 166
>UniRef50_Q8UB54 Cluster: Zinc-binding dehydrogenase; n=3;
Rhizobiales|Rep: Zinc-binding dehydrogenase -
Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Length = 338
Score = 51.6 bits (118), Expect = 2e-05
Identities = 42/140 (30%), Positives = 64/140 (45%), Gaps = 5/140 (3%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVTRKPRQILQARSRFL 428
+V GDRV ++P +PC C C+ G +LC + + + +++A
Sbjct: 73 DVTVFKAGDRVVVDPNLPCGTCASCRKGLTNLCSTLKAYGVSHNGGFAEFSVVRADH--- 129
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVV----LVLGAGPIGLLTMLTAKAFG 596
L S + + + +Q G+ VV LV GAGPIGLL L+ K+ G
Sbjct: 130 LHGIGSMPYHVAALAEPLACVVNGMQSAGIGESGVVPENALVFGAGPIGLLLALSLKSRG 189
Query: 597 AHKVLIIDILQSRLDFAKSL 656
V + DI +SRL FA+ L
Sbjct: 190 IATVTMADINESRLAFAQDL 209
Score = 35.5 bits (78), Expect = 1.1
Identities = 38/150 (25%), Positives = 61/150 (40%), Gaps = 3/150 (2%)
Frame = +1
Query: 73 LVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 252
L + P+ ++ L+R+ G+C +D+ + G P+I GHE +G VA + S
Sbjct: 16 LAELPVADLPPGHALVRVKASGLCHTDIDVLH-ARYGDGAF--PVIPGHEYAGEVAAVAS 72
Query: 253 KSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADFCF 432
+ + P GT +S R+ T T A +G + AD
Sbjct: 73 DVTVFKAGDRVVVDPNLPCGTCASCRKGLTNLCST-LKAYGVSHNGGFAEFSVVRADHLH 131
Query: 433 ---KLPDHVTMEEGALLEPLAVGIHACKRA 513
+P HV AL EPLA ++ + A
Sbjct: 132 GIGSMPYHV----AALAEPLACVVNGMQSA 157
>UniRef50_A4QH16 Cluster: Putative uncharacterized protein; n=1;
Corynebacterium glutamicum R|Rep: Putative
uncharacterized protein - Corynebacterium glutamicum
(strain R)
Length = 363
Score = 51.6 bits (118), Expect = 2e-05
Identities = 41/134 (30%), Positives = 59/134 (44%), Gaps = 1/134 (0%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVTRKPRQILQARSRFL 428
E VGDRV I P C C C GR + C +M ++ + Q++ + F
Sbjct: 87 EGNGFNVGDRVVICPMFYCGKCYACSVGRVNACKEMSVYGCYEDGSLVDEQVVPYANLFK 146
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
+ S D + G +G V+V GAGPIG+L + K G +V
Sbjct: 147 IPDSLPLDLA--PIVEPISIAMQACKRGRPVSGEKVIVNGAGPIGVLAVRYLKDQGC-EV 203
Query: 609 LIIDILQSRLDFAK 650
+ D++QSRLD AK
Sbjct: 204 AVTDMVQSRLDLAK 217
Score = 46.0 bits (104), Expect = 8e-04
Identities = 38/150 (25%), Positives = 66/150 (44%), Gaps = 10/150 (6%)
Frame = +1
Query: 91 PEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI-----GSK 255
P I + M V +CG+D H W + E P+I GHEA+G++ ++ G+
Sbjct: 35 PAIVPGSARISMAAVTLCGTDAHIWDDD----YASELPIIQGHEAAGIITEMDPSDEGNG 90
Query: 256 SRI*QLVIEWP-----*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKHAA 420
+ V+ P AC VG ++ ++ S G+LV
Sbjct: 91 FNVGDRVVICPMFYCGKCYACSVGRVNACKE---------MSVYGCYEDGSLVDEQVVPY 141
Query: 421 DFCFKLPDHVTMEEGALLEPLAVGIHACKR 510
FK+PD + ++ ++EP+++ + ACKR
Sbjct: 142 ANLFKIPDSLPLDLAPIVEPISIAMQACKR 171
>UniRef50_A3JMN6 Cluster: Dehydrogenase; n=4; Bacteria|Rep:
Dehydrogenase - Rhodobacterales bacterium HTCC2150
Length = 346
Score = 51.6 bits (118), Expect = 2e-05
Identities = 34/135 (25%), Positives = 62/135 (45%), Gaps = 1/135 (0%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPV-TRKPRQILQARSRFLL 431
V N+ +G +V + P C C C G +H+C + F + + A + +L
Sbjct: 78 VTNVKMGQKVVVRPLDHCNDCPACDAGHFHICHQLNFLGLDTDGAMQEIWTVPAHTLHVL 137
Query: 432 QAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVL 611
DH A R+ + + G V+V+G GPIG+L + A+ +G +V+
Sbjct: 138 PDDLRLDHAALIEPVAVACHDVRMSD--LKEGEDVVVIGGGPIGILVAMVARDYGG-RVV 194
Query: 612 IIDILQSRLDFAKSL 656
+ ++ ++RL A+ L
Sbjct: 195 VSEVNKARLAIAQKL 209
Score = 44.0 bits (99), Expect = 0.003
Identities = 43/174 (24%), Positives = 74/174 (42%), Gaps = 9/174 (5%)
Frame = +1
Query: 22 MATDNLTALLYKPNDLRLVQTPIPEISD-DEVLLRMDCVGICGSDVHYWQKGQCGHFVLE 198
M ++A Y+ + +V+ ++ + EV +R+ GICG+D+H + L
Sbjct: 1 MIETKISAAFYRGDKSFVVEQTAAQVPNAGEVAVRVAYCGICGTDMHVYHGNMDARVGLN 60
Query: 199 EPMIMGHEASGVVAKIG---SKSRI*QLVIEWP*S-----PACRVGTASSVRQDDTTYAP 354
++GHE SG V IG + ++ Q V+ P PAC G Q +
Sbjct: 61 R--VVGHEMSGTVEAIGANVTNVKMGQKVVVRPLDHCNDCPACDAGHFHICHQLNFLGLD 118
Query: 355 T*SSAPRPQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAE 516
T G + + A LPD + ++ AL+EP+AV H + ++
Sbjct: 119 T---------DGAMQEIWTVPAHTLHVLPDDLRLDHAALIEPVAVACHDVRMSD 163
>UniRef50_Q8R7K0 Cluster: L-threonine 3-dehydrogenase; n=3; cellular
organisms|Rep: L-threonine 3-dehydrogenase -
Thermoanaerobacter tengcongensis
Length = 347
Score = 51.6 bits (118), Expect = 2e-05
Identities = 24/66 (36%), Positives = 36/66 (54%)
Frame = +1
Query: 52 YKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASG 231
Y +V+ IP+I DEVL+++ ICG+DVH + + ++ P MGHE G
Sbjct: 12 YHKEGADIVKKEIPKIGPDEVLIKVKATSICGTDVHIYVWNEWAKSRIKPPKTMGHEFVG 71
Query: 232 VVAKIG 249
V +IG
Sbjct: 72 EVVEIG 77
Score = 44.4 bits (100), Expect = 0.002
Identities = 33/134 (24%), Positives = 50/134 (37%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V ++ VGD V+ E + C C C+TG H+C + + I S +
Sbjct: 80 VTSVKVGDLVSAETHIVCGKCRACRTGNAHICENTLILGVDTDGAFAEYIKVPESNVWIN 139
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
+ P G G G V V+G GPIG++ + K GA +
Sbjct: 140 D--KNIPLEILSIQEPLGNAVHTVFSGDVVGKSVAVIGCGPIGMMAIPLLKRTGAAAIFA 197
Query: 615 IDILQSRLDFAKSL 656
I+ R + A L
Sbjct: 198 IEPADYRRELAHKL 211
>UniRef50_UPI0000498928 Cluster: zinc-containing alcohol
dehydrogenase; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
zinc-containing alcohol dehydrogenase - Entamoeba
histolytica HM-1:IMSS
Length = 343
Score = 51.2 bits (117), Expect = 2e-05
Identities = 42/138 (30%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPD---MIFCATPPVTRKPRQILQARSR 422
+VK + VGD V+I C C FC+ G + C I C + +I A S
Sbjct: 72 DVKKIKVGDHVSINCITFCGNCWFCQHGYINNCEYGGWEIGCRENGTMAEYVRIPFADSS 131
Query: 423 FLLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAH 602
+ +D G+ V+ G V G +V V+G GP+GL +ML K A
Sbjct: 132 LNVIPKEVKDEQCLLVGDVLSSGYFGVELGEVKEGDIVTVIGCGPVGLCSMLCCKMKKA- 190
Query: 603 KVLIIDILQSRLDFAKSL 656
KV+ +DI L++A+ L
Sbjct: 191 KVIALDINTQCLEYAQKL 208
Score = 35.9 bits (79), Expect = 0.86
Identities = 19/64 (29%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Frame = +1
Query: 61 NDLRLVQTPIPEISDD-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVV 237
N L +++ P+I+ + + ++++ IC SD+H KG+ ++ +I+GHE G V
Sbjct: 10 NQLEIIEVEKPQINHETDAVVKITFASICSSDIHIL-KGKVPR--AKKGVILGHEGVGEV 66
Query: 238 AKIG 249
+IG
Sbjct: 67 VEIG 70
>UniRef50_Q63FG9 Cluster: Zinc-containing alcohol dehydrogenase;
possible sorbitol dehydrogenase; n=3; Bacillus
cereus|Rep: Zinc-containing alcohol dehydrogenase;
possible sorbitol dehydrogenase - Bacillus cereus
(strain ZK / E33L)
Length = 340
Score = 51.2 bits (117), Expect = 2e-05
Identities = 37/155 (23%), Positives = 67/155 (43%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A+ Y D+R+ + E+ ++V +++ GICGSD+H + + + ++GHE
Sbjct: 4 AVWYGEKDIRIEERETKELQPNDVKVKVAWAGICGSDLHAYLHPD--SVPMNKNTVLGHE 61
Query: 223 ASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVR 402
SG + ++GS + C + T A Q+ G
Sbjct: 62 FSGEIVEVGS-----HVTKFKEGDRVCIYPMMLKDPSNAETERFITLDAVGAQIDGGFAE 116
Query: 403 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACK 507
Y FK+PD++++E A++EP AV + K
Sbjct: 117 YVILPQKTIFKIPDNLSLEVAAMVEPAAVSFQSIK 151
Score = 50.0 bits (114), Expect = 5e-05
Identities = 21/46 (45%), Positives = 31/46 (67%)
Frame = +3
Query: 501 VQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRL 638
+++ V G V+V GAGPIGL +L AKA GA ++++D+ SRL
Sbjct: 150 IKDSNVEEGDTVVVYGAGPIGLFAVLGAKAAGASNIIVVDLFDSRL 195
>UniRef50_Q1A676 Cluster: Alcohol dehydrogenase; n=4; Bacteria|Rep:
Alcohol dehydrogenase - Roseburia inulinivorans
Length = 403
Score = 51.2 bits (117), Expect = 2e-05
Identities = 22/69 (31%), Positives = 44/69 (63%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A+L + + + P+PE+ DD++L++++ G+CG+D H +++ F L P+ +GHE
Sbjct: 44 AMLTELEKFEIKEFPMPEVGDDDILVKVEGCGVCGTDAHEFKRDP---FSL-IPVALGHE 99
Query: 223 ASGVVAKIG 249
+G + K+G
Sbjct: 100 GTGEIVKMG 108
Score = 36.7 bits (81), Expect = 0.49
Identities = 16/38 (42%), Positives = 23/38 (60%)
Frame = +3
Query: 534 VLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFA 647
V+V G GPIGL+ + + G + +D Q+RLDFA
Sbjct: 219 VVVQGCGPIGLICIAVLRTMGIENITAVDGNQARLDFA 256
>UniRef50_A5V690 Cluster: Alcohol dehydrogenase GroES domain protein
precursor; n=2; Bacteria|Rep: Alcohol dehydrogenase
GroES domain protein precursor - Sphingomonas wittichii
RW1
Length = 354
Score = 51.2 bits (117), Expect = 2e-05
Identities = 40/137 (29%), Positives = 62/137 (45%), Gaps = 9/137 (6%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLC-----PDMIFCATPPVTRKPRQILQA- 413
EV++ VGDRV + + C C+ C+ G +LC P + P + + +
Sbjct: 74 EVRDFRVGDRVLLPAILGCGRCDPCRAGDVYLCRTQSAPMIYGQGFPGIGGSQAEAVAVP 133
Query: 414 ---RSRFLLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTA 584
R+ + L S + G + V G VV V+G GP+G ++ A
Sbjct: 134 NADRNLWRLPPGLSDEVGIMLTDNLATAWFC-ARRARVRPGDVVAVIGLGPVGQQAVMAA 192
Query: 585 KAFGAHKVLIIDILQSR 635
KA GA +VL ID+L+SR
Sbjct: 193 KAMGAERVLGIDLLRSR 209
Score = 37.5 bits (83), Expect = 0.28
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 2/79 (2%)
Frame = +1
Query: 31 DNLTALLYK-PNDLRLVQTPIPEISDDE-VLLRMDCVGICGSDVHYWQKGQCGHFVLEEP 204
D + AL++ P + P P + D + L+R G+CGSD+H + G H
Sbjct: 3 DFMKALIHLGPGRIGYESVPDPILPDRQGALVRTTMCGLCGSDLHLYH-GAPAH----GS 57
Query: 205 MIMGHEASGVVAKIGSKSR 261
+GHEA G V ++GS+ R
Sbjct: 58 YCIGHEAVGEVVEVGSEVR 76
>UniRef50_A4QUV6 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 250
Score = 51.2 bits (117), Expect = 2e-05
Identities = 21/50 (42%), Positives = 34/50 (68%)
Frame = +3
Query: 501 VQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAK 650
++ G+S G ++ GAGPIGL+ + A+A GAH ++I D+ RL+FA+
Sbjct: 41 IRVAGLSLGRGAVICGAGPIGLIALAAARASGAHPIVITDVEPRRLEFAR 90
Score = 41.9 bits (94), Expect = 0.013
Identities = 20/44 (45%), Positives = 28/44 (63%)
Frame = +1
Query: 382 LHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
+H + RY H A + KLPD ++ EGALLEPL+V +H + A
Sbjct: 1 MHWCMRRYKVHPARWLHKLPDSLSYAEGALLEPLSVVLHGIRVA 44
>UniRef50_Q97NH4 Cluster: Alcohol dehydrogenase, zinc-containing;
n=31; cellular organisms|Rep: Alcohol dehydrogenase,
zinc-containing - Streptococcus pneumoniae
Length = 352
Score = 50.8 bits (116), Expect = 3e-05
Identities = 39/138 (28%), Positives = 62/138 (44%), Gaps = 5/138 (3%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPD---MIFC-ATPPVTRKPRQILQARSR 422
V N GD+V I C C +CK G Y C D IF + + ++ A +
Sbjct: 73 VSNFKKGDKVLISCVCACGKCYYCKKGIYAHCEDEGGWIFGHLIDGMQAEYLRVPHADNT 132
Query: 423 FLLQAS*SRDHGRRSATGA-PRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGA 599
D + P G V +G V G V ++G+GP+GL +LTA+ +
Sbjct: 133 LYHTPEDLSDEALVMLSDILPTGYEIGVLKGKVEPGCSVAIIGSGPVGLAALLTAQFYSP 192
Query: 600 HKVLIIDILQSRLDFAKS 653
K++++D+ +RL+ A S
Sbjct: 193 AKLIMVDLDDNRLETALS 210
>UniRef50_Q3ZWK2 Cluster: Alcohol dehydrogenase, zinc-containing;
n=3; Dehalococcoides|Rep: Alcohol dehydrogenase,
zinc-containing - Dehalococcoides sp. (strain CBDB1)
Length = 343
Score = 50.8 bits (116), Expect = 3e-05
Identities = 28/68 (41%), Positives = 38/68 (55%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 225
LL KP +LRL + P VLL++ C ICG+DV +++ GH LE P I+GHE
Sbjct: 5 LLEKPGELRLAEVVTPYCPKGGVLLKVLCCAICGTDVKMFRR---GHRDLEYPRILGHEI 61
Query: 226 SGVVAKIG 249
+ V G
Sbjct: 62 AAEVVCSG 69
Score = 48.4 bits (110), Expect = 1e-04
Identities = 36/129 (27%), Positives = 56/129 (43%), Gaps = 3/129 (2%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SRD 452
G RV + PG+ C C C GR +LC + + + + +
Sbjct: 76 GCRVQVYPGIACGVCPLCLQGRENLCRKVKIIGFNYDGGLAEYMALPPESLPVGLNIIPE 135
Query: 453 H--GRRSATGAPRGGHSRVQEG-GVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDI 623
H ++ P Q V G VLVLGAGP+GLL + A+ GA +VL+ ++
Sbjct: 136 HVSDEEASLAEPLASCIHAQSVCRVGDGDRVLVLGAGPLGLLQAMLARHNGAEQVLVAEV 195
Query: 624 LQSRLDFAK 650
L R++ A+
Sbjct: 196 LPERVNGAE 204
>UniRef50_Q1QWS0 Cluster: Alcohol dehydrogenase GroES-like protein;
n=1; Chromohalobacter salexigens DSM 3043|Rep: Alcohol
dehydrogenase GroES-like protein - Chromohalobacter
salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 349
Score = 50.8 bits (116), Expect = 3e-05
Identities = 42/163 (25%), Positives = 67/163 (41%)
Frame = +1
Query: 40 TALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 219
T + +P + L P P+ + E +LR+ VGICG+D+H + G +F P ++GH
Sbjct: 3 TLVCTQPRHMELRDVPEPQCAPGEAMLRIRRVGICGTDIHAY-GGNQPYFTY--PRVLGH 59
Query: 220 EASGVVAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLV 399
E SG + +G + P G + RQ T G +
Sbjct: 60 ELSGDIVGVGEGVDESLVGHSAYVIPYLHCGECRACRQGKTNCCQH-MQVIGVHRDGGMA 118
Query: 400 RYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESRRD 528
Y D + E+ AL+E L++G HA +R+ D
Sbjct: 119 EYLSVPVDH-LVTSSTLDAEQLALVECLSIGAHAVRRSAIEAD 160
Score = 40.7 bits (91), Expect = 0.030
Identities = 32/127 (25%), Positives = 57/127 (44%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SR 449
VG + P + C C C+ G+ + C M + L L+ +S +
Sbjct: 77 VGHSAYVIPYLHCGECRACRQGKTNCCQHMQVIGVHR-DGGMAEYLSVPVDHLVTSS-TL 134
Query: 450 DHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQ 629
D + + G V+ + A + +V+GAGPIG+ + A++ GA +VL++D +
Sbjct: 135 DAEQLALVECLSIGAHAVRRSAIEADELAVVVGAGPIGIGIVQIAQSRGA-RVLVVDTNR 193
Query: 630 SRLDFAK 650
RL F +
Sbjct: 194 ERLAFCR 200
>UniRef50_Q1IJN0 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Acidobacteria bacterium Ellin345|Rep: Alcohol
dehydrogenase GroES-like - Acidobacteria bacterium
(strain Ellin345)
Length = 350
Score = 50.8 bits (116), Expect = 3e-05
Identities = 38/136 (27%), Positives = 60/136 (44%), Gaps = 1/136 (0%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSR-FL 428
EV + GD V+ E V C C C+TG+ H+C + ++ S +
Sbjct: 79 EVTLVKEGDFVSAEMHVNCGKCLQCRTGQAHICQHVKIIGVDANGAFAEYVVIPESNIWK 138
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
L + +++ ++ P G G A V + G GPIGL ++ AKA GA KV
Sbjct: 139 LDPAIPQEY---ASILDPLGNAVHTVLAGDIAAKTVAITGCGPIGLFSIAVAKACGATKV 195
Query: 609 LIIDILQSRLDFAKSL 656
I++ + R AK +
Sbjct: 196 FAIEVNEHRRAIAKKM 211
Score = 49.6 bits (113), Expect = 6e-05
Identities = 20/59 (33%), Positives = 35/59 (59%)
Frame = +1
Query: 79 QTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSK 255
+ P+P+ +EVL+++ ICG+D+H + Q ++ P+I GHE G V +GS+
Sbjct: 21 EVPVPKFGPNEVLVKVKVASICGTDLHIYNWDQWAQRRIKPPLIPGHEFCGDVVAVGSE 79
>UniRef50_Q11VP8 Cluster: Zinc-type alcohol dehydrogenase; n=2;
Sphingobacteriales|Rep: Zinc-type alcohol dehydrogenase
- Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB
9469)
Length = 385
Score = 50.8 bits (116), Expect = 3e-05
Identities = 24/71 (33%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEIS-DDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 219
A+ +KP + + P+I D+++L++ ICGSD+H + G F P+IMGH
Sbjct: 4 AVFHKPGHISVDTVEDPKIEKSDDIILKVTSTAICGSDLHIYD----GFFPQARPLIMGH 59
Query: 220 EASGVVAKIGS 252
E G+V ++G+
Sbjct: 60 EFMGIVEEVGN 70
Score = 38.3 bits (85), Expect = 0.16
Identities = 20/54 (37%), Positives = 28/54 (51%)
Frame = +3
Query: 489 GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAK 650
G S + + G V + G+GP+GL+ A GA +V+ ID L RL AK
Sbjct: 174 GWSAIDWAQLKGGETVAIFGSGPVGLMAQKAAWLKGAGRVIAIDPLNYRLAKAK 227
>UniRef50_A0JVV9 Cluster: Alcohol dehydrogenase GroES domain
protein; n=2; Arthrobacter|Rep: Alcohol dehydrogenase
GroES domain protein - Arthrobacter sp. (strain FB24)
Length = 343
Score = 50.8 bits (116), Expect = 3e-05
Identities = 23/70 (32%), Positives = 38/70 (54%)
Frame = +1
Query: 55 KPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 234
+P +R+ + +P EVL+R + G+CGSD+H W G G+ + ++GHE G
Sbjct: 23 QPRSIRVFEQDLPVPGPGEVLVRTEYCGLCGSDLHIW-NGDDGYDWVPCGTVLGHEIVGT 81
Query: 235 VAKIGSKSRI 264
V ++ S I
Sbjct: 82 VVRVNGSSAI 91
>UniRef50_P38105 Cluster: Starvation-sensing protein rspB; n=36;
Proteobacteria|Rep: Starvation-sensing protein rspB -
Escherichia coli (strain K12)
Length = 339
Score = 50.8 bits (116), Expect = 3e-05
Identities = 27/69 (39%), Positives = 40/69 (57%), Gaps = 1/69 (1%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMIMGHE 222
L+ KPN L +V+ IP S EV +++ GICGSD H ++ GH + P ++GHE
Sbjct: 5 LIEKPNQLAIVEREIPTPSAGEVRVKVKLAGICGSDSHIYR----GHNPFAKYPRVIGHE 60
Query: 223 ASGVVAKIG 249
GV+ +G
Sbjct: 61 FFGVIDAVG 69
Score = 44.4 bits (100), Expect = 0.002
Identities = 35/137 (25%), Positives = 62/137 (45%), Gaps = 5/137 (3%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVTRKPRQILQARSRFLL 431
V++ VG+RVA++P V C +C C G+ ++C + + ++ A++ + +
Sbjct: 72 VESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAVLGVHADGGFSEYAVVPAKNAWKI 131
Query: 432 QAS*SRDHG---RRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAK-AFGA 599
+ + + A GH + E VLV GAGPIGL + K +
Sbjct: 132 PEAVADQYAVMIEPFTIAANVTGHGQPTE-----NDTVLVYGAGPIGLTIVQVLKGVYNV 186
Query: 600 HKVLIIDILQSRLDFAK 650
V++ D + RL+ AK
Sbjct: 187 KNVIVADRIDERLEKAK 203
>UniRef50_Q62AB8 Cluster: Oxidoreductase, zinc-binding dehydrogenase
family; n=28; Bacteria|Rep: Oxidoreductase, zinc-binding
dehydrogenase family - Burkholderia mallei (Pseudomonas
mallei)
Length = 378
Score = 50.4 bits (115), Expect = 4e-05
Identities = 48/171 (28%), Positives = 74/171 (43%), Gaps = 19/171 (11%)
Frame = +1
Query: 58 PNDLRLVQTPIPEISDDEVLLRMDCVGICGSDV-------HYWQKGQCGHFVLEEPMIMG 216
P D RL Q P+P+ DE+L +++ VGIC D+ +W +V + PMI G
Sbjct: 33 PQDYRLEQVPVPKPGPDEILTQVERVGICMGDIKTFRGAPSFWGDAVQPRYV-KPPMIPG 91
Query: 217 HE-ASGVVA----------KIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*S 363
HE VVA K+G + Q+V W C G ++ D
Sbjct: 92 HEFVCRVVALGPGAERRGVKVGDRVISEQIVPCWS-CRFCGHGQYWMCQKHDL------- 143
Query: 364 SAPRPQLHGNLVRYYKHAAD-FCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
+ +HG + Y + ++PD + +E L+EPL+ +HA RA
Sbjct: 144 YGFQNNVHGAMAEYMIFTKEAIVHRVPDSIPTDEAILIEPLSCSLHAADRA 194
Score = 37.9 bits (84), Expect = 0.21
Identities = 16/33 (48%), Positives = 20/33 (60%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLC 350
E + + VGDRV E VPC C FC G+Y +C
Sbjct: 106 ERRGVKVGDRVISEQIVPCWSCRFCGHGQYWMC 138
>UniRef50_A5FCD7 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=5; Bacteria|Rep: Alcohol dehydrogenase,
zinc-binding domain protein - Flavobacterium johnsoniae
UW101
Length = 356
Score = 50.4 bits (115), Expect = 4e-05
Identities = 43/153 (28%), Positives = 69/153 (45%)
Frame = +1
Query: 55 KPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 234
KP + +L + IPE + EVLL++ +GICG+D+H + G +F E P I+GHE +
Sbjct: 27 KPQEFKLKEKEIPEPKEGEVLLKIKRIGICGTDIHAF-GGTQPYF--EYPRILGHELAAE 83
Query: 235 VAKIGSKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKH 414
K G+ + + + P GT + R T + G + Y
Sbjct: 84 YVK-GNAAGF-KPGDKVTFIPYFNCGTCVACRNGLTNCCVN-IKVFGVHIDGGMAEYVSI 140
Query: 415 AADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
+ + +E AL+EPLA+ H +RA
Sbjct: 141 PEQYLLH-GQGLDYDELALVEPLAIAAHGVRRA 172
Score = 46.8 bits (106), Expect = 5e-04
Identities = 35/127 (27%), Positives = 57/127 (44%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQAS*SRD 452
GD+V P C C C+ G + C ++ + + + ++LL D
Sbjct: 95 GDKVTFIPYFNCGTCVACRNGLTNCCVNIKVFGVH-IDGGMAEYVSIPEQYLLHGQ-GLD 152
Query: 453 HGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQS 632
+ + V+ V + VLV+GAGPIG+ + AK GA KV+++DI
Sbjct: 153 YDELALVEPLAIAAHGVRRAAVKSTDTVLVMGAGPIGIGLIQFAKIAGA-KVIVMDINDY 211
Query: 633 RLDFAKS 653
RL+F K+
Sbjct: 212 RLNFCKT 218
>UniRef50_Q4PP82 Cluster: Putative zinc-containing alcohol
dehydrogenase; n=4; Endopterygota|Rep: Putative
zinc-containing alcohol dehydrogenase - Lysiphlebus
testaceipes (Greenbugs aphid parastoid)
Length = 340
Score = 50.4 bits (115), Expect = 4e-05
Identities = 40/141 (28%), Positives = 62/141 (43%), Gaps = 7/141 (4%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTR----KPRQILQARSR 422
VK +G VAI+P C C+FC TG+YH C + T + R ++
Sbjct: 74 VKGFKIGQSVAIDPNSGCNKCDFCHTGKYHFCDNGGINNTIGIFRDGGWSTHAVVPESQV 133
Query: 423 FLLQAS*SRDHGRRSATGAPRG--GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFG 596
+LL + ++A P H V+ G +LV+G+G IGLL G
Sbjct: 134 YLLPSGVEMP---QAALAEPLSCLAHGWDIINPVTVGTNILVIGSGIIGLLWACLLHLHG 190
Query: 597 AHK-VLIIDILQSRLDFAKSL 656
+ K V I + +++R + K L
Sbjct: 191 SRKTVTISEPIEARREAVKKL 211
Score = 45.2 bits (102), Expect = 0.001
Identities = 26/65 (40%), Positives = 37/65 (56%), Gaps = 2/65 (3%)
Frame = +1
Query: 64 DLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP--MIMGHEASGVV 237
+L LV IP+ DE+L+R+ GICG+D+H G F + + +GHE SGV+
Sbjct: 12 NLSLVHGEIPKPGPDEILVRVHYSGICGTDLHILD----GSFPAKSDGNLTLGHEFSGVI 67
Query: 238 AKIGS 252
IGS
Sbjct: 68 EDIGS 72
>UniRef50_Q67N85 Cluster: L-threonine 3-dehydrogenase; n=10;
Bacteria|Rep: L-threonine 3-dehydrogenase -
Symbiobacterium thermophilum
Length = 351
Score = 50.4 bits (115), Expect = 4e-05
Identities = 37/136 (27%), Positives = 52/136 (38%), Gaps = 1/136 (0%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLL 431
EV VGD V+ E + C C C G YHLC + + +
Sbjct: 79 EVTACKVGDYVSAETHIVCNRCPRCHMGEYHLCENTKILGVDTDGAFAEYVAVPEQNIWV 138
Query: 432 QAS*SRDHG-RRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
+D + P G G VL+ G GPIG++++ AK GA V
Sbjct: 139 N---DKDIPFELQSIQEPLGNAVHTALNGDLTARSVLITGCGPIGIMSVPVAKMAGAEIV 195
Query: 609 LIIDILQSRLDFAKSL 656
+ +DI + RL A L
Sbjct: 196 MAMDINEYRLQLAGQL 211
Score = 44.0 bits (99), Expect = 0.003
Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Frame = +1
Query: 73 LVQTPIPEISDDEVLLRMDCVGICGSDVHY--WQKGQCGHFVLEEPMIMGHEASGVVAKI 246
L + PIP I +VL+++ ICG+D H W G ++ P+ +GHE +G V +
Sbjct: 19 LQEVPIPTIGPRDVLVKVRAASICGTDYHIYTWDPWSAGR--VKPPLTIGHELAGEVVAV 76
Query: 247 G 249
G
Sbjct: 77 G 77
>UniRef50_Q62CY1 Cluster: Alcohol dehydrogenase, zinc-containing;
n=32; Bacteria|Rep: Alcohol dehydrogenase,
zinc-containing - Burkholderia mallei (Pseudomonas
mallei)
Length = 346
Score = 50.0 bits (114), Expect = 5e-05
Identities = 38/136 (27%), Positives = 60/136 (44%), Gaps = 4/136 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPD---MIFCATPPVTRKPRQILQARSRF 425
V GDRV I C CE+C+ G Y C ++ + +I A++
Sbjct: 73 VSTFKEGDRVLISCISSCGQCEYCRRGMYSHCATGGWILGNRIDGTQAEYVRIPHAQTSL 132
Query: 426 LLQAS*SRDHGRRSATGA-PRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAH 602
A + + + P G V G V G V ++GAGPIGL +LTA+ +
Sbjct: 133 YRIAPGADEEALVMLSDILPTGFECGVLNGRVQPGGTVAIIGAGPIGLAALLTAQFYSPA 192
Query: 603 KVLIIDILQSRLDFAK 650
++++ID +RL A+
Sbjct: 193 QIVMIDPDPNRLALAR 208
Score = 37.9 bits (84), Expect = 0.21
Identities = 25/73 (34%), Positives = 40/73 (54%), Gaps = 2/73 (2%)
Frame = +1
Query: 37 LTALLYK-PNDLRLVQTPIPEIS-DDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 210
+ AL+Y P L + P+PE++ +V++R+ ICG+D+H KG E +
Sbjct: 1 MKALVYHGPGRKSLDERPMPELAAPTDVIVRVTRTTICGTDLHI-LKGDVPS--CEPGRV 57
Query: 211 MGHEASGVVAKIG 249
+GHE GVV + G
Sbjct: 58 LGHEGVGVVHRAG 70
>UniRef50_Q1J6P8 Cluster: Zn-dependent alcohol dehydrogenase; n=19;
cellular organisms|Rep: Zn-dependent alcohol
dehydrogenase - Streptococcus pyogenes serotype M4
(strain MGAS10750)
Length = 363
Score = 50.0 bits (114), Expect = 5e-05
Identities = 38/137 (27%), Positives = 57/137 (41%), Gaps = 4/137 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPD--MIFCATPPVTRKPRQILQARSRFL 428
V N +GD+V I C C +CK G C D I T+ + L
Sbjct: 87 VTNFKIGDKVIISCVTSCHTCYYCKRGLSSHCEDGGWILGHLINGTQAEYVHIPHADGSL 146
Query: 429 LQAS*SRDHGRRSATG--APRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAH 602
A + D P V V G V ++GAGP+GL +LT + F
Sbjct: 147 YHAPDTIDDEALVMLSDILPTSYEIGVLPSHVKPGDNVCIVGAGPVGLAALLTVQFFSPA 206
Query: 603 KVLIIDILQSRLDFAKS 653
++++D+ Q+RL+ AK+
Sbjct: 207 NIIMVDLSQNRLEAAKT 223
Score = 33.1 bits (72), Expect = 6.0
Identities = 22/74 (29%), Positives = 38/74 (51%), Gaps = 2/74 (2%)
Frame = +1
Query: 34 NLTALLY-KPNDLRLVQTPIPEI-SDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPM 207
N+ A Y +L+L+ P P I + ++++ ICG+D+H G +E
Sbjct: 14 NMKAATYLSTGNLQLIDKPKPVIIKPTDAIVQLVKTTICGTDLHILG-GDVP--ACKEGT 70
Query: 208 IMGHEASGVVAKIG 249
I+GHE G+V ++G
Sbjct: 71 ILGHEGIGIVKEVG 84
>UniRef50_Q1AVM7 Cluster: Alcohol dehydrogenase GroES-like protein;
n=1; Rubrobacter xylanophilus DSM 9941|Rep: Alcohol
dehydrogenase GroES-like protein - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 341
Score = 50.0 bits (114), Expect = 5e-05
Identities = 23/65 (35%), Positives = 36/65 (55%)
Frame = +1
Query: 55 KPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 234
+P + + + P P EVLLR+ G+CGSDVH + + G + P+ +GHE +G
Sbjct: 10 RPGEAGVAELPAPRPGPGEVLLRVAACGVCGSDVHAF-RSDPGFEWISTPVTLGHEFAGT 68
Query: 235 VAKIG 249
V +G
Sbjct: 69 VEALG 73
>UniRef50_A6VLA0 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Actinobacillus succinogenes 130Z|Rep:
Alcohol dehydrogenase GroES domain protein -
Actinobacillus succinogenes 130Z
Length = 339
Score = 50.0 bits (114), Expect = 5e-05
Identities = 36/134 (26%), Positives = 56/134 (41%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
V ++ VGD V + C +C C+TG +++C ++ L
Sbjct: 73 VTHVKVGDYVVSDIVNSCGHCYACRTGHHNVCKNLQVTGVHSQGGFAEYAKTRADNVYLV 132
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
+ H G ++AG V+V G+GP GL M A+A GA +VLI
Sbjct: 133 DTNKIPHKTACLIEPYAVGVEINTRASIAAGDKVVVFGSGPAGLAVMQVARARGA-EVLI 191
Query: 615 IDILQSRLDFAKSL 656
DI + RL A+ +
Sbjct: 192 TDIFEERLQLAREM 205
Score = 44.0 bits (99), Expect = 0.003
Identities = 22/66 (33%), Positives = 39/66 (59%), Gaps = 1/66 (1%)
Frame = +1
Query: 55 KPNDLRLVQTPIPEIS-DDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASG 231
+P +L + P P ++ DD+V++++ GICGSD+ + G+ + + P I+GHE G
Sbjct: 8 QPFELTVADVPAPTVTKDDDVIIKVAFGGICGSDIGIYTG---GNSLAKYPAIIGHEFVG 64
Query: 232 VVAKIG 249
V + G
Sbjct: 65 TVVETG 70
>UniRef50_A1SLI2 Cluster: Alcohol dehydrogenase GroES domain
protein; n=6; Actinomycetales|Rep: Alcohol dehydrogenase
GroES domain protein - Nocardioides sp. (strain BAA-499
/ JS614)
Length = 352
Score = 50.0 bits (114), Expect = 5e-05
Identities = 26/67 (38%), Positives = 35/67 (52%)
Frame = +1
Query: 52 YKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASG 231
Y P D+RL + P P DEV LR+ CG+DV GH L P +GHE +G
Sbjct: 7 YAPEDVRLEEVPEPTCGPDEVKLRVRNCSTCGTDVKILHN---GHQNLTPPRTIGHEIAG 63
Query: 232 VVAKIGS 252
V ++G+
Sbjct: 64 EVVEVGA 70
>UniRef50_A0JVX5 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=1; Arthrobacter sp. FB24|Rep: Alcohol
dehydrogenase, zinc-binding domain protein -
Arthrobacter sp. (strain FB24)
Length = 355
Score = 50.0 bits (114), Expect = 5e-05
Identities = 25/66 (37%), Positives = 40/66 (60%), Gaps = 1/66 (1%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPE-ISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 219
A+L NDL P P+ + ++ VL+R+ VG+CGSDV + G+ H+ P+++GH
Sbjct: 4 AILNGLNDLEYADIPEPQPVGENPVLVRVGAVGVCGSDVLRYGHGKAYHY----PLVLGH 59
Query: 220 EASGVV 237
E S +V
Sbjct: 60 EFSAIV 65
Score = 33.5 bits (73), Expect = 4.6
Identities = 16/40 (40%), Positives = 22/40 (55%)
Frame = +3
Query: 537 LVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
LV+GAGPIG L + G +VL+ DI +L+ L
Sbjct: 164 LVIGAGPIGALAAQWLRILGCSRVLVADIDDRKLEIMSRL 203
>UniRef50_Q5K7P7 Cluster: (R,R)-butanediol dehydrogenase, putative;
n=2; Dikarya|Rep: (R,R)-butanediol dehydrogenase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 441
Score = 50.0 bits (114), Expect = 5e-05
Identities = 22/63 (34%), Positives = 41/63 (65%), Gaps = 1/63 (1%)
Frame = +1
Query: 64 DLRLVQTPIPEISDD-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 240
D+R+V PIP+I+ D +V++++ ICGSD+H + G +++ I+GHE G++
Sbjct: 42 DVRMVDAPIPDITQDTDVIVKVTGTTICGSDLHLYHSEMLG---MQKGDILGHEFMGIID 98
Query: 241 KIG 249
++G
Sbjct: 99 RVG 101
Score = 39.1 bits (87), Expect = 0.092
Identities = 24/59 (40%), Positives = 32/59 (54%)
Frame = +3
Query: 480 PRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
P H+ V + GV G +V + G GPIG+ + A GA KV ID +RL A+SL
Sbjct: 202 PTSYHA-VVDTGVQKGDIVGIWGLGPIGICCVKWALLKGASKVYAIDTNPTRLALARSL 259
>UniRef50_Q62K93 Cluster: Oxidoreductase, zinc-binding dehydrogenase
family; n=41; Bacteria|Rep: Oxidoreductase, zinc-binding
dehydrogenase family - Burkholderia mallei (Pseudomonas
mallei)
Length = 353
Score = 49.6 bits (113), Expect = 6e-05
Identities = 37/142 (26%), Positives = 65/142 (45%), Gaps = 3/142 (2%)
Frame = +3
Query: 237 GQDRFEVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCP-DMIFCATPPVT-RKPRQILQ 410
G+ E + +GDRV E VPC C +CK+G+Y +C IF V + ++
Sbjct: 76 GEGAAEHFGVALGDRVIAEQIVPCGTCRYCKSGQYWMCEVHHIFGFQREVADGGMAEYMR 135
Query: 411 ARSRFLLQAS*SRDHGRRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAK 587
S ++ +A P V G + VV++ GAGP+GL+ AK
Sbjct: 136 IPSGAIVHPIPLGISLEDAAIIEPLACAIHTVNRGDIQLDDVVVIAGAGPLGLMMTQVAK 195
Query: 588 AFGAHKVLIIDILQSRLDFAKS 653
+++++D +++R A++
Sbjct: 196 LKTPRRLVVVDPVEARRALARA 217
Score = 38.3 bits (85), Expect = 0.16
Identities = 43/178 (24%), Positives = 75/178 (42%), Gaps = 14/178 (7%)
Frame = +1
Query: 37 LTALL-YKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSD--VHYWQKGQCG--HFVLEE 201
+TA++ + P D R+ + P + E+++R+ GIC SD H K G ++
Sbjct: 1 MTAIVCHAPEDYRVERVAKPRANARELVIRIGACGICASDCKCHAGAKMFWGGPSPWVKA 60
Query: 202 PMIMGHEASGVVAKIGSKS------RI*QLVIEWP*SP--ACRVGTASSVRQDDTTYAPT 357
P+I GHE G V +G + + VI P CR + + +
Sbjct: 61 PVIPGHEFFGYVEALGEGAAEHFGVALGDRVIAEQIVPCGTCRYCKSGQYWMCEVHHI-- 118
Query: 358 *SSAPRPQLHGNLVRYYK-HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRAESRRD 528
R G + Y + + +P +++E+ A++EPLA IH R + + D
Sbjct: 119 -FGFQREVADGGMAEYMRIPSGAIVHPIPLGISLEDAAIIEPLACAIHTVNRGDIQLD 175
>UniRef50_Q2LXU3 Cluster: 6-hydroxycyclohex-1-ene-1-carboxyl-CoA
dehydrogenase; n=4; Proteobacteria|Rep:
6-hydroxycyclohex-1-ene-1-carboxyl-CoA dehydrogenase -
Syntrophus aciditrophicus (strain SB)
Length = 370
Score = 49.6 bits (113), Expect = 6e-05
Identities = 41/130 (31%), Positives = 61/130 (46%), Gaps = 7/130 (5%)
Frame = +3
Query: 270 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFC-ATPPVTRKPRQILQARSRFLLQAS*S 446
+G V I +PCR CE CKTGR + C + +F + + + S L + +
Sbjct: 93 IGKEVLIPAVLPCRKCELCKTGRGNRCLNQMFIGCSHGIYGGNSDYIPVPSLDLCEIK-N 151
Query: 447 RDHGR-----RSATGAPRGGHSRVQEGGVSAGHVVLVLGA-GPIGLLTMLTAKAFGAHKV 608
R R A+ A + + + V G V+V+GA G +GL T AKA GA V
Sbjct: 152 RPSTRPLENYSVASDAVTTPYQAMIKAKVGIGDNVIVIGATGGVGLYTAQIAKAMGADVV 211
Query: 609 LIIDILQSRL 638
+ IDI + +L
Sbjct: 212 IGIDIAEQKL 221
Score = 44.0 bits (99), Expect = 0.003
Identities = 19/60 (31%), Positives = 36/60 (60%)
Frame = +1
Query: 58 PNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVV 237
P L+L + P+PE+ + +VL+++ G+C +D+ ++ V + P+ +GHE SG V
Sbjct: 28 PGQLQLTEIPVPELKEGDVLVKIAGCGVCHTDLGFF--FDAVPTVTKPPLTLGHEVSGTV 85
>UniRef50_A6AJT3 Cluster: Alcohol dehydrogenase, zinc-containing;
n=3; Vibrionales|Rep: Alcohol dehydrogenase,
zinc-containing - Vibrio harveyi HY01
Length = 348
Score = 49.6 bits (113), Expect = 6e-05
Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 4/169 (2%)
Frame = +3
Query: 162 LAEGSMRTLRAGRTNDHGTRSFRSSGQDRFEVKNLTVGDRVAIEPGVPCRYCEFCKTGRY 341
+ ++ T + G H S DR V N GDRV + C C+ C+ ++
Sbjct: 44 ILRNNVATFKPGTIMGHEGVGIVESCGDR--VNNFRPGDRVIVSCITSCGSCKMCQMSKF 101
Query: 342 HLCPDMIFCATPPVTRKPRQILQA----RSRFLLQAS*SRDHGRRSATGAPRGGHSRVQE 509
C D + + + ++ S L+ D + P G V +
Sbjct: 102 GQCLDGGWLLGNEIDGCQAEYVRVPHGDTSLHLVPDDIDTDCLVLLSDIFPTGYEVGVLD 161
Query: 510 GGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
G V G V V+G GP+GL ++T+K F ++ ID RL AK L
Sbjct: 162 GQVQPGCSVAVIGCGPVGLAALMTSKFFSPSEIYAIDNNPHRLQVAKEL 210
Score = 36.3 bits (80), Expect = 0.65
Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Frame = +1
Query: 70 RLVQTPIPEI-SDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 246
+LV+ PEI + +V+++++ ICG+D+H + + IMGHE G+V
Sbjct: 13 KLVEREKPEIINQSDVIVKIEKTTICGTDLHILRNNVA---TFKPGTIMGHEGVGIVESC 69
Query: 247 GSK 255
G +
Sbjct: 70 GDR 72
>UniRef50_A4FB48 Cluster: Putative uncharacterized protein; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: Putative
uncharacterized protein - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 764
Score = 49.6 bits (113), Expect = 6e-05
Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +1
Query: 13 ASDMATDNLTALLYKPND--LRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGH 186
A++ A+ T LL+ D L P+P +S EVL+R+ ICGSD+H GH
Sbjct: 402 AANDASGTATGLLWHGADEGFALSSRPLPRLSGGEVLVRVRMATICGSDLH----TIAGH 457
Query: 187 FVLEEPMIMGHEASGVVAKIGSKSR 261
P ++GHE G V + G + R
Sbjct: 458 RSTPVPTVLGHEVVGTVVETGGEVR 482
Score = 33.5 bits (73), Expect = 4.6
Identities = 17/45 (37%), Positives = 29/45 (64%)
Frame = +3
Query: 516 VSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAK 650
++AG VV+VLG G +GL + A+ GA V+ D+ ++R + A+
Sbjct: 581 LAAGDVVVVLGCGMLGLTAVAYARDRGAVAVVACDLDEARREAAR 625
>UniRef50_A0QTC9 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;
n=1; Mycobacterium smegmatis str. MC2 155|Rep:
2-deoxy-scyllo-inosamine dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 360
Score = 49.6 bits (113), Expect = 6e-05
Identities = 40/148 (27%), Positives = 65/148 (43%), Gaps = 1/148 (0%)
Frame = +3
Query: 210 HGTRSFRSSGQDRFEVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVT 386
H S D + +LT G RV I P C C C+TGR ++C + + T
Sbjct: 71 HEAAGIVESVGDPADASSLT-GTRVVISPVRSCGDCHACRTGRENVCERVSVLGCYEDGT 129
Query: 387 RKPRQILQARSRFLLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGL 566
R ++ + + + + S + V+ G AG + LVLG GPIGL
Sbjct: 130 LATRVVVPVSALHQVPDAVPSELAPLSEPASI--ALQAVRRGRPVAGELALVLGCGPIGL 187
Query: 567 LTMLTAKAFGAHKVLIIDILQSRLDFAK 650
+T++ + G V+ +D ++ R FA+
Sbjct: 188 ITIMALRRAGV-DVVAVDTVEERARFAE 214
Score = 48.8 bits (111), Expect = 1e-04
Identities = 38/152 (25%), Positives = 63/152 (41%), Gaps = 1/152 (0%)
Frame = +1
Query: 58 PNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVV 237
P L L I + E ++R++ V +CG+D+H W+ G ++ P++ GHEA+G+V
Sbjct: 22 PGRLTLEDRKIASPHNGEAVVRVENVTLCGTDLHIWE----GEYLNPFPIVQGHEAAGIV 77
Query: 238 AKIGSKSRI*QLV-IEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYKH 414
+G + L SP G + R S + G L
Sbjct: 78 ESVGDPADASSLTGTRVVISPVRSCGDCHACRTGRENVCERVSVLGCYE-DGTLATRVVV 136
Query: 415 AADFCFKLPDHVTMEEGALLEPLAVGIHACKR 510
++PD V E L EP ++ + A +R
Sbjct: 137 PVSALHQVPDAVPSELAPLSEPASIALQAVRR 168
>UniRef50_Q00SV0 Cluster: COG1064: Zn-dependent alcohol
dehydrogenases; n=2; Ostreococcus|Rep: COG1064:
Zn-dependent alcohol dehydrogenases - Ostreococcus tauri
Length = 1719
Score = 49.6 bits (113), Expect = 6e-05
Identities = 41/148 (27%), Positives = 67/148 (45%), Gaps = 4/148 (2%)
Frame = +1
Query: 43 ALLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 222
A L + DL ++ +P+++ V LR++ G+CGSD H G G + + P + GHE
Sbjct: 1378 AALAQNEDLVPIKYRLPDMTPSSVELRVEYCGLCGSDDHL-IVGDYGEYAV-WPQVCGHE 1435
Query: 223 ASGVVAKIGSKSRI----*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHG 390
GVV ++GS ++ + W S +C R D+ + + G
Sbjct: 1436 VVGVVTQVGSAVTTLKPGQRVGVGWQ-SSSCH-DCEWCARGDEQLCSAVGCTCCEGNKGG 1493
Query: 391 NLVRYYKHAADFCFKLPDHVTMEEGALL 474
R + A FC+K+PD + E A L
Sbjct: 1494 FADRMRLNDAQFCYKIPDELASAEVAPL 1521
>UniRef50_A0V7I1 Cluster: Alcohol dehydrogenase GroES-like; n=2;
Comamonadaceae|Rep: Alcohol dehydrogenase GroES-like -
Delftia acidovorans SPH-1
Length = 567
Score = 49.2 bits (112), Expect = 9e-05
Identities = 24/62 (38%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
Frame = +1
Query: 67 LRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMIMGHEASGVVAK 243
L L Q +P EVLLR+ G+CG+D+H + + HF+ P+ +GHE SG +A
Sbjct: 229 LTLTQADMPAPGPGEVLLRVHSAGVCGTDLHIAEWTRSYHFLTPALPVTIGHEFSGEIAA 288
Query: 244 IG 249
+G
Sbjct: 289 LG 290
Score = 46.0 bits (104), Expect = 8e-04
Identities = 39/119 (32%), Positives = 51/119 (42%), Gaps = 2/119 (1%)
Frame = +3
Query: 264 LTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTR-KPRQILQARSRFLLQAS 440
LTVG VA+ P V C C C +G + C P + R+ + A
Sbjct: 300 LTVGQMVAVRPSVTCGRCAACTSGNFDGCTTRRGIGVLRNGGFAPWAAVPLRNCVPVPAG 359
Query: 441 *SRDHGRRSATGAPRG-GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
G +A P H V+ GV GH VLVLG G IG L A+A GA +V++
Sbjct: 360 ---VQGDVAALAEPLTVSHEAVRTAGVRPGHRVLVLGPGNIGQGIALFARAAGAAQVVV 415
>UniRef50_A0LRZ3 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Acidothermus cellulolyticus 11B|Rep:
Alcohol dehydrogenase GroES domain protein -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 336
Score = 49.2 bits (112), Expect = 9e-05
Identities = 26/68 (38%), Positives = 39/68 (57%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 225
L+ +P + L + P +EVL+R VGICG+DV G+ + PM++GHE
Sbjct: 7 LVREPGAIELAEVADPVPGAEEVLVRPTLVGICGTDVDI-VDGRVDPLFIRYPMVLGHEW 65
Query: 226 SGVVAKIG 249
+GVVA+ G
Sbjct: 66 TGVVAEPG 73
>UniRef50_Q4LED7 Cluster: Sorbitol dehydrogenase; n=1; uncultured
crenarchaeote 10-H-08|Rep: Sorbitol dehydrogenase -
uncultured crenarchaeote 10-H-08
Length = 339
Score = 49.2 bits (112), Expect = 9e-05
Identities = 35/130 (26%), Positives = 59/130 (45%), Gaps = 5/130 (3%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVT-----RKPRQILQARSRFLLQA 437
GDRV + V C C +C+ G +CP + + P R PR ++ + +L+
Sbjct: 73 GDRVFVHHHVTCGKCYYCREGSPTMCPLFLQTSIDPCGFAEFFRVPRVNVERGA--VLRL 130
Query: 438 S*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLII 617
+ ++ G AGH + ++GAGP G + ++ AKAFGA V +
Sbjct: 131 PDELEWSEAVFIEPAACVLRALRRAGFRAGHTLSLVGAGPTGTIFIVMAKAFGAPVVAVS 190
Query: 618 DILQSRLDFA 647
++ + R D A
Sbjct: 191 ELSKYRRDMA 200
>UniRef50_P77360 Cluster: Uncharacterized zinc-type alcohol
dehydrogenase-like protein yphC; n=24; Bacteria|Rep:
Uncharacterized zinc-type alcohol dehydrogenase-like
protein yphC - Escherichia coli (strain K12)
Length = 353
Score = 49.2 bits (112), Expect = 9e-05
Identities = 37/131 (28%), Positives = 58/131 (44%), Gaps = 3/131 (2%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCA---TPPVTRKPRQILQARSRFLLQAS* 443
GDRV + C +C C+ G C A + + + LL +
Sbjct: 89 GDRVLVYHISGCGFCPNCRRGFPISCTGEGKAAYGWQRDGGHAEYLLAEEKDLILLPDAL 148
Query: 444 SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDI 623
S + G + G + + G VS VLV+G GP+G++ M+ AK GA +++ +D+
Sbjct: 149 SYEDGAFISCGVGTA-YEGILRGEVSGSDNVLVVGLGPVGMMAMMLAKGRGAKRIIGVDM 207
Query: 624 LQSRLDFAKSL 656
L RL AK L
Sbjct: 208 LPERLAMAKQL 218
Score = 43.6 bits (98), Expect = 0.004
Identities = 27/71 (38%), Positives = 39/71 (54%), Gaps = 5/71 (7%)
Frame = +1
Query: 64 DLRLVQTPIPEISDDEVLLRMDCVGICGSDVHY-WQKGQCGHFVLEEPM----IMGHEAS 228
DLR V P P I+ +VL++M GICGSDVHY + + + ++P+ I GHE
Sbjct: 16 DLREVAVPTPGIN--QVLIKMKSSGICGSDVHYIYHQHRATAAAPDKPLYQGFINGHEPC 73
Query: 229 GVVAKIGSKSR 261
G + +G R
Sbjct: 74 GQIVAMGQGCR 84
>UniRef50_O45687 Cluster: Alcohol dehydrogenase 2; n=3;
Caenorhabditis|Rep: Alcohol dehydrogenase 2 -
Caenorhabditis elegans
Length = 351
Score = 49.2 bits (112), Expect = 9e-05
Identities = 25/65 (38%), Positives = 39/65 (60%), Gaps = 2/65 (3%)
Frame = +1
Query: 67 LRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE--PMIMGHEASGVVA 240
L + Q +P+ ++E+L++++ GIC SD+H W+ G F P+I GHE +G V
Sbjct: 22 LEVRQVSVPQPQENELLVKIEYSGICHSDLHTWE----GDFEYASICPLIGGHEGAGTVV 77
Query: 241 KIGSK 255
IGSK
Sbjct: 78 TIGSK 82
Score = 36.7 bits (81), Expect = 0.49
Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 5/140 (3%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEP-GVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFL 428
+VK +GDR I+ C CE+CKTG LC D I ++ L R
Sbjct: 82 KVKGWNIGDRAGIKLINANCLNCEYCKTGHEPLC-DHIQNYGIDRHGTFQEYLTIRDIDA 140
Query: 429 LQAS*SRDHGRRSATGAPRGG---HSRVQEGGVSAGHVVLVLGA-GPIGLLTMLTAKAFG 596
++ S D +A GG + ++ V G +V++ GA G +G + AKA G
Sbjct: 141 IKV--SNDTNLAAAAPVLCGGVTAYKSLKATNVKPGQIVVLTGAGGGLGSFGIQYAKAMG 198
Query: 597 AHKVLIIDILQSRLDFAKSL 656
+V+ +D + S+ D ++L
Sbjct: 199 M-RVVAVDHI-SKEDHCRNL 216
>UniRef50_Q8A1P2 Cluster: Sorbitol dehydrogenase; n=4;
Bacteroidetes|Rep: Sorbitol dehydrogenase - Bacteroides
thetaiotaomicron
Length = 338
Score = 48.8 bits (111), Expect = 1e-04
Identities = 41/158 (25%), Positives = 80/158 (50%), Gaps = 2/158 (1%)
Frame = +1
Query: 49 LYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 228
+ P+++++V+ P + EVL+R+ VG CGSD++ + G+ + +++ P+I GHE
Sbjct: 6 IVNPSEMKVVELEKPTVGAGEVLVRIKYVGFCGSDLNTF-LGR--NPMVKLPVIPGHEVG 62
Query: 229 GVVAKIGSKSRI-*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRY 405
V+ +IG + + +P G +S R + A + Q +G + Y
Sbjct: 63 AVIEEIGPDVPAGFEKGMNVTLNPYTNCGKCASCR-NGRVNACEHNETLGVQRNGVMCEY 121
Query: 406 YKHAADFCFKLP-DHVTMEEGALLEPLAVGIHACKRAE 516
+ +P +++ + AL+EP++VG HA RA+
Sbjct: 122 --AVLPWTKIIPAGNISSRDCALIEPMSVGFHAVSRAQ 157
>UniRef50_A6PRU8 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Victivallis vadensis ATCC BAA-548|Rep:
Alcohol dehydrogenase GroES domain protein - Victivallis
vadensis ATCC BAA-548
Length = 328
Score = 48.8 bits (111), Expect = 1e-04
Identities = 24/64 (37%), Positives = 37/64 (57%)
Frame = +1
Query: 58 PNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVV 237
P +V PIPEI+DD++L+++ G+C S+ + W Q G + GHE+ GVV
Sbjct: 9 PRKSEVVDVPIPEITDDQLLVKVTYTGMCHSEWYPWTVAQPGE-------LFGHESVGVV 61
Query: 238 AKIG 249
A+ G
Sbjct: 62 ARCG 65
>UniRef50_A3DME0 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Staphylothermus marinus F1|Rep: Alcohol
dehydrogenase GroES domain protein - Staphylothermus
marinus (strain ATCC 43588 / DSM 3639 / F1)
Length = 333
Score = 48.8 bits (111), Expect = 1e-04
Identities = 24/71 (33%), Positives = 45/71 (63%)
Frame = +1
Query: 46 LLYKPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 225
+L+ P DLRL + P +D V +R+ +GICG+D ++ KG + ++++P+I GHE
Sbjct: 5 VLHGPYDLRLEEVDDPIPKNDWVRIRVKRIGICGTDKAFY-KGT--YKLMKKPLIPGHEI 61
Query: 226 SGVVAKIGSKS 258
+G++ +G +
Sbjct: 62 AGIIDMVGENA 72
>UniRef50_A0RXG2 Cluster: Zn-dependent alcohol dehydrogenase; n=2;
Thermoprotei|Rep: Zn-dependent alcohol dehydrogenase -
Cenarchaeum symbiosum
Length = 352
Score = 48.8 bits (111), Expect = 1e-04
Identities = 34/136 (25%), Positives = 65/136 (47%), Gaps = 1/136 (0%)
Frame = +3
Query: 252 EVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARS-RFL 428
+ K + GD V I P V C C C+ G +LC D + ++++ S R+L
Sbjct: 78 DAKGFSKGDPVLIYPWVGCGRCPACREGSENLC-DTPGSVGLFLDGGYAELVRVPSYRYL 136
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
+ G S A ++ V++ ++ ++V+GAG +GL+ + AKA K+
Sbjct: 137 VGIDGIDPDGATSLACAALTAYNSVKKADAASPGFIVVIGAGGLGLMGVQIAKAVTKAKI 196
Query: 609 LIIDILQSRLDFAKSL 656
+ +D+ ++L A+ +
Sbjct: 197 ICVDLDDNKLKMAREM 212
Score = 40.3 bits (90), Expect = 0.040
Identities = 22/78 (28%), Positives = 43/78 (55%), Gaps = 9/78 (11%)
Frame = +1
Query: 55 KPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQ---CGHFV------LEEPM 207
KP ++ +++P P +EV++++ G+C SD+H W+ G G F+ ++ P+
Sbjct: 5 KPLEVSELESPSPR--GEEVIVKVTSAGVCHSDLHLWEGGYDMGDGEFLKVTDRGIKYPV 62
Query: 208 IMGHEASGVVAKIGSKSR 261
GHE +G V + G ++
Sbjct: 63 TPGHEIAGTVLEAGPDAK 80
>UniRef50_P39400 Cluster: Uncharacterized zinc-type alcohol
dehydrogenase-like protein yjjN; n=29;
Gammaproteobacteria|Rep: Uncharacterized zinc-type
alcohol dehydrogenase-like protein yjjN - Escherichia
coli (strain K12)
Length = 337
Score = 48.8 bits (111), Expect = 1e-04
Identities = 23/65 (35%), Positives = 35/65 (53%)
Frame = +1
Query: 55 KPNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 234
+P +L Q IP D+E L+++ VGICG+D+H W Q P ++GHE G
Sbjct: 8 QPKELVWKQREIPIPGDNEALIKIKSVGICGTDIHAWGGNQP---FFSYPRVLGHEICGE 64
Query: 235 VAKIG 249
+ +G
Sbjct: 65 IVGLG 69
Score = 46.8 bits (106), Expect = 5e-04
Identities = 38/127 (29%), Positives = 57/127 (44%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQARSRFLLQ 434
+ +L G +VA+ P V C+ C CK+GR + C + I + L +L
Sbjct: 72 IADLKNGQQVAVIPYVACQQCPACKSGRTNCC-EKISVIGVHQDGGFSEYLSVPVANILP 130
Query: 435 AS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLI 614
A H+ V+ ++ G VLV+GAGPIGL AKA GA +V++
Sbjct: 131 ADGIDPQAAALIEPFAISAHA-VRRAAIAPGEQVLVVGAGPIGLGAAAIAKADGA-QVVV 188
Query: 615 IDILQSR 635
D +R
Sbjct: 189 ADTSPAR 195
>UniRef50_UPI00015B5FCF Cluster: PREDICTED: similar to putative
zinc-containing alcohol dehydrogenase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to putative
zinc-containing alcohol dehydrogenase - Nasonia
vitripennis
Length = 339
Score = 48.4 bits (110), Expect = 1e-04
Identities = 46/153 (30%), Positives = 68/153 (44%), Gaps = 5/153 (3%)
Frame = +1
Query: 67 LRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLE--EPMIMGHEASGVVA 240
L L + IP+ DDEVL+R+ GICG+D+H + G F + EP+I GHE G V
Sbjct: 13 LTLQKASIPKPKDDEVLIRVAYSGICGTDLHILE----GTFPCKQNEPLIPGHEFCGTVE 68
Query: 241 KIG---SKSRI*QLVIEWP*SPACRVGTASSVRQDDTTYAPT*SSAPRPQLHGNLVRYYK 411
+G ++ Q V P + C + V +S +G +
Sbjct: 69 AVGVSVKNFKVGQRVTVDP-NSGCSMCDDCHVGCYHLCVNGGVNSTIGIFRNGGWATHCC 127
Query: 412 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKR 510
+ +P+ V ME+ AL EPL+ H KR
Sbjct: 128 VPEVQVYHVPEGVEMEQAALSEPLSCLAHGWKR 160
Score = 46.0 bits (104), Expect = 8e-04
Identities = 39/138 (28%), Positives = 54/138 (39%), Gaps = 4/138 (2%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQ-ARSRFLL 431
VKN VG RV ++P C C+ C G YHLC + +T + R +
Sbjct: 74 VKNFKVGQRVTVDPNSGCSMCDDCHVGCYHLCVNGGVNSTIGIFRNGGWATHCCVPEVQV 133
Query: 432 QAS*SRDHGRRSATGAPRG--GHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHK 605
++A P H + + G VLVLGAG IGLL G K
Sbjct: 134 YHVPEGVEMEQAALSEPLSCLAHGWKRMNPIHVGQKVLVLGAGIIGLLWSSILHLHGLRK 193
Query: 606 VLIIDILQ-SRLDFAKSL 656
+ + Q R + AK +
Sbjct: 194 TVTVSEPQDKRKEMAKKM 211
>UniRef50_Q7U377 Cluster: Putative Zinc-binding dehydrogenase; n=2;
Bordetella|Rep: Putative Zinc-binding dehydrogenase -
Bordetella parapertussis
Length = 360
Score = 48.4 bits (110), Expect = 1e-04
Identities = 26/68 (38%), Positives = 39/68 (57%), Gaps = 1/68 (1%)
Frame = +1
Query: 58 PNDLRLVQTPIPEI-SDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 234
P L VQ P+PE+ + DE L+R++ GICG+D ++ G GH +I GHE G
Sbjct: 11 PRRLEYVQLPLPEVLAPDEALVRVEGCGICGTDYERYE-GSLGHV---PELIPGHEPVGR 66
Query: 235 VAKIGSKS 258
+ +IG +
Sbjct: 67 IERIGDSA 74
Score = 42.3 bits (95), Expect = 0.010
Identities = 36/152 (23%), Positives = 63/152 (41%), Gaps = 12/152 (7%)
Frame = +3
Query: 237 GQDRFEVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTR--------K 392
G + L GDRVA++P C C +C G + LC I P++
Sbjct: 71 GDSAAQRMQLKEGDRVAVQPHYGCGVCSYCVEGMFQLCARKINLGLSPLSEGCGLWGGFA 130
Query: 393 PRQILQARS--RFLLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGL 566
+L+ + + + D + GA G + G G VL+ G G GL
Sbjct: 131 EHMMLKGNAIVHKMPDSLPIEDAVMFNPLGA--GFEWAITSAGTRVGDDVLIFGPGQRGL 188
Query: 567 LTMLTAKAFGAHKVLIIDILQS--RLDFAKSL 656
++ A GA+++++ + + +L+ A+SL
Sbjct: 189 ACVIAAVIAGANRIVVTGLQKDAYKLELARSL 220
>UniRef50_Q6MJG4 Cluster: Putative alcohol dehydrogenase I; n=1;
Bdellovibrio bacteriovorus|Rep: Putative alcohol
dehydrogenase I - Bdellovibrio bacteriovorus
Length = 332
Score = 48.4 bits (110), Expect = 1e-04
Identities = 36/130 (27%), Positives = 58/130 (44%), Gaps = 3/130 (2%)
Frame = +3
Query: 273 GDRVAIEPGVPCRYCEFCKTGRYHLC--PDMIFCATPPVTRKPRQI-LQARSRFLLQAS* 443
GD A+ PC +C +C+TG +LC P F + + AR+ +
Sbjct: 79 GDLYAVHGPNPCGHCNYCRTGHDNLCNDPSRTFIGLGQDGAYAEYLKVPARNIVKVPKGI 138
Query: 444 SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDI 623
S + + H+ +GGV G VL +G G +G+ + A A GA +V +D+
Sbjct: 139 SPEVAAVATDAVLTPYHAIKTKGGVGLGSKVLAIGLGGLGMNGVQIALALGA-EVTAVDL 197
Query: 624 LQSRLDFAKS 653
+ L+ AKS
Sbjct: 198 KDANLETAKS 207
Score = 42.7 bits (96), Expect = 0.007
Identities = 24/64 (37%), Positives = 34/64 (53%)
Frame = +1
Query: 64 DLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 243
+L LV+ P P +V+L++ GIC SD+H G +E MGHEA G V +
Sbjct: 12 ELSLVEVPKPTPGPLDVILKIRAAGICHSDLHVLH----GEVPYKESFTMGHEACGEVVE 67
Query: 244 IGSK 255
GS+
Sbjct: 68 KGSE 71
>UniRef50_Q5BFT1 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 391
Score = 48.4 bits (110), Expect = 1e-04
Identities = 54/197 (27%), Positives = 81/197 (41%), Gaps = 36/197 (18%)
Frame = +1
Query: 19 DMATDNLTALLYK------PNDLRLVQTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQC 180
++ATDN L K P D+R+ Q P +V LR GICGSD+H + G
Sbjct: 6 EIATDNENMPLMKALQFHGPRDVRVEQIEEPVCGKGQVKLRNTYCGICGSDLHEYTSGPV 65
Query: 181 -----GHFVLEE--PMIMGHEASGVVA---------KIGSKSRI*QLVIEWP*SPACRVG 312
H + + P++MGHE GVV K G K+ + + + P C++G
Sbjct: 66 LIPKGAHSITKATAPVVMGHEFGGVVEEVGEGITHLKPGQKAVVRPTIFDRK-CPPCKIG 124
Query: 313 ---TASSV-----------RQDDTTYAPT*SSAPRPQLHGNLVRYYKHAADFCFKLPDHV 450
++ R + + R G A+ + +PD+V
Sbjct: 125 YEYCCENIGFIGLSGMLFFRIKQAVRSGQANVPMRTGYGGGFAEKIVAPAEHFYPIPDNV 184
Query: 451 TMEEGALLEPLAVGIHA 501
T E A++EPLAV HA
Sbjct: 185 TPESMAMIEPLAVAWHA 201
Score = 33.1 bits (72), Expect = 6.0
Identities = 16/42 (38%), Positives = 25/42 (59%)
Frame = +3
Query: 525 GHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAK 650
G VLV+G GP+GL + K GA+ +I ++ ++R AK
Sbjct: 210 GDNVLVVGGGPLGLCILQVLKMRGANFTIIAELTETRKKSAK 251
>UniRef50_Q7UU62 Cluster: Sorbitol dehydrogenase; n=1; Pirellula
sp.|Rep: Sorbitol dehydrogenase - Rhodopirellula baltica
Length = 414
Score = 48.0 bits (109), Expect = 2e-04
Identities = 42/163 (25%), Positives = 67/163 (41%), Gaps = 20/163 (12%)
Frame = +1
Query: 85 PIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE--PMIMGHEASGVVAKIGSKS 258
P P + D +L++D GICG+D H + KG+ + P + GHE G + +IG +
Sbjct: 51 PYPTVDHDSAILKVDMSGICGTDRHIF-KGEASELRGKSIFPYVGGHEVIGTIVEIGDNA 109
Query: 259 RI*QLVIEWP*SPACRVGTASSV----------RQDDTT-------YAPT*SSAPRPQLH 387
+ P RV A V ++TT Y ++ P L
Sbjct: 110 AKVMDYDKQPLQVGDRVAIAVEVNCGHCFYCRKHYNNTTCLNQIQAYGLHPNADTLPYLR 169
Query: 388 GNLVRY-YKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRA 513
G Y + FK+PD ++ + +E +AV H+ RA
Sbjct: 170 GGFAEYIFIRPGTHLFKVPDEMSTDVAVFVEEMAVAYHSLARA 212
Score = 35.5 bits (78), Expect = 1.1
Identities = 19/48 (39%), Positives = 27/48 (56%)
Frame = +3
Query: 513 GVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAKSL 656
G G+ V VLG GP+G+L + A GA + D+ RL+ AK+L
Sbjct: 222 GFGPGNSVAVLGNGPLGILHGIMASIHGAGLRIATDLSDLRLEKAKNL 269
>UniRef50_Q2LQ73 Cluster: Zinc-binding dehydrogenase; n=2;
Bacteria|Rep: Zinc-binding dehydrogenase - Syntrophus
aciditrophicus (strain SB)
Length = 362
Score = 48.0 bits (109), Expect = 2e-04
Identities = 37/136 (27%), Positives = 57/136 (41%), Gaps = 5/136 (3%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT----PPVTRKPRQILQARSR 422
VK+L VGDRV + C C C+ G + C F + P + L R
Sbjct: 86 VKSLNVGDRVVVSCVAFCGECRSCRQGLHARCEKTGFGSFGMNGPDGGQAEYVRLPGADR 145
Query: 423 FLLQAS*SRDHGRRSATG-APRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGA 599
+ + S G G+ + G + G V+V+GAGP+GL M +A+
Sbjct: 146 YCFKIPESLTFQDVLFCGDVLSAGYYGAEMGDIQRGETVVVVGAGPVGLCAMASARLREP 205
Query: 600 HKVLIIDILQSRLDFA 647
+++ +D RLD A
Sbjct: 206 SRIIAVDTNPYRLDAA 221
>UniRef50_A7NMA5 Cluster: Alcohol dehydrogenase GroES domain
protein; n=2; Chloroflexaceae|Rep: Alcohol dehydrogenase
GroES domain protein - Roseiflexus castenholzii DSM
13941
Length = 370
Score = 48.0 bits (109), Expect = 2e-04
Identities = 30/75 (40%), Positives = 42/75 (56%), Gaps = 3/75 (4%)
Frame = +1
Query: 37 LTALLYKPND--LRLVQTPIPEIS-DDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPM 207
+ AL +P +RLVQ P PEI+ DEVL+R+ VGICG+D G+ +
Sbjct: 1 MDALAVQPGSAGIRLVQRPQPEITRPDEVLVRIIRVGICGTDREIVSGGRAKASDHATDL 60
Query: 208 IMGHEASGVVAKIGS 252
++GHE G V +GS
Sbjct: 61 VIGHEMFGRVEAVGS 75
>UniRef50_A7HAS7 Cluster: Alcohol dehydrogenase GroES domain
protein; n=9; Bacteria|Rep: Alcohol dehydrogenase GroES
domain protein - Anaeromyxobacter sp. Fw109-5
Length = 384
Score = 48.0 bits (109), Expect = 2e-04
Identities = 24/60 (40%), Positives = 35/60 (58%)
Frame = +3
Query: 471 TGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKVLIIDILQSRLDFAK 650
T A G+ + +S G V+V GAGP+GL M +A GA +V+ +D + RLDFA+
Sbjct: 160 TDALPTGYQGAEMCNLSGGETVVVFGAGPVGLFAMKSAWLLGAGRVIAVDKVGYRLDFAR 219
Score = 39.5 bits (88), Expect = 0.069
Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 5/79 (6%)
Frame = +1
Query: 37 LTALLYK-PNDLRLVQTPIPEISD-DEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 210
+ AL Y+ P +R+ P P I + +LR+ C ICGSD+H H ++ + I
Sbjct: 1 MRALTYEGPARVRVRHKPDPRIEHPQDAILRVTCAAICGSDLHLL------HGLVPDTRI 54
Query: 211 ---MGHEASGVVAKIGSKS 258
GHE GVV +GS++
Sbjct: 55 GSTFGHEIVGVVEDVGSQA 73
>UniRef50_A1K6Y3 Cluster: Putative alcohol dehydrogenase; n=1;
Azoarcus sp. BH72|Rep: Putative alcohol dehydrogenase -
Azoarcus sp. (strain BH72)
Length = 368
Score = 48.0 bits (109), Expect = 2e-04
Identities = 40/142 (28%), Positives = 67/142 (47%), Gaps = 13/142 (9%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVTRKPRQILQ-------A 413
VK++ GDRV + PG+ C C +CK G C F + + + + A
Sbjct: 82 VKSVRPGDRVYVNPGLSCGECRYCKQGEPTRCDAYTFMGYFGFGKGSQALFERYPYAGYA 141
Query: 414 RSRFLLQAS*SRDHGRRSATGAPRGG-----HSRVQEGGVSAGHVVLVLGA-GPIGLLTM 575
A+ R + S+ A R G +S +++ + AG VL+LGA G +G+ +
Sbjct: 142 EYMTAPVANLVRLPDQVSSAQAARFGYMGTAYSALRKAALQAGQSVLILGATGTLGVGAV 201
Query: 576 LTAKAFGAHKVLIIDILQSRLD 641
L A FGA +V+++ ++ LD
Sbjct: 202 LLALGFGAARVVVVGRDRALLD 223
>UniRef50_A0QZF0 Cluster: Oxidoreductase, zinc-binding dehydrogenase
family protein; n=3; Bacteria|Rep: Oxidoreductase,
zinc-binding dehydrogenase family protein -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 360
Score = 48.0 bits (109), Expect = 2e-04
Identities = 40/136 (29%), Positives = 60/136 (44%), Gaps = 2/136 (1%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCP-DMIFCATPPVTRKPRQIL-QARSRFL 428
V VGDRV + V C C+ C+ G Y C D R +L + R+
Sbjct: 88 VTRFGVGDRVLLYHIVGCGLCDNCRRGFYISCSGDRASYGWQRDGGHARYVLAEERTCIP 147
Query: 429 LQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLTMLTAKAFGAHKV 608
L S G A G + ++ GVS H +LV+G GP+GL + + GA V
Sbjct: 148 LPDELSFVDGALIACGFATA-YEGLRRAGVSGDHDLLVVGLGPVGLAAGMIGRGMGAATV 206
Query: 609 LIIDILQSRLDFAKSL 656
+ ++ +R ++A SL
Sbjct: 207 IGVEPSTTRREWADSL 222
Score = 41.1 bits (92), Expect = 0.023
Identities = 44/156 (28%), Positives = 65/156 (41%), Gaps = 14/156 (8%)
Frame = +1
Query: 49 LYKPNDLRLV--QTPIPEISDDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP----MI 210
+Y P D V Q + +VLL M GICGSD+ Y +G G+ ++ P ++
Sbjct: 13 VYLPGDSTAVLKQFDVRPPGPGQVLLEMGASGICGSDIGYIYRGYKGYRGIDGPAYQGVV 72
Query: 211 MGHEASG-VVA------KIGSKSRI*QL-VIEWP*SPACRVGTASSVRQDDTTYAPT*SS 366
GHE +G +VA + G R+ ++ CR G S D +Y
Sbjct: 73 AGHEPAGRIVATGEGVTRFGVGDRVLLYHIVGCGLCDNCRRGFYISCSGDRASYG----- 127
Query: 367 APRPQLHGNLVRYYKHAADFCFKLPDHVTMEEGALL 474
Q G RY C LPD ++ +GAL+
Sbjct: 128 ---WQRDGGHARYVLAEERTCIPLPDELSFVDGALI 160
>UniRef50_Q6BC32 Cluster: Glycerol dehydrogenase; n=3;
Saccharomycetales|Rep: Glycerol dehydrogenase - Pichia
angusta (Yeast) (Hansenula polymorpha)
Length = 380
Score = 48.0 bits (109), Expect = 2e-04
Identities = 52/183 (28%), Positives = 79/183 (43%), Gaps = 27/183 (14%)
Frame = +1
Query: 46 LLYKPNDLRLVQT-PIPEISD-DEVLLRMDCVGICGSDV-HYWQKGQCGHFV-------- 192
L Y ND+R +T P PEI + ++V +++ GICG+D+ + G F
Sbjct: 5 LYYGTNDIRYSETVPEPEIKNPNDVKIKVSYCGICGTDLKEFTYSGGPVFFPKQGTKDKI 64
Query: 193 --LEEPMIMGHEASGVVAKIGSKSRI*Q----LVIEWP*SPACRVGTASSVRQDDTTYAP 354
E P+ GHE SG V ++GS + + +E + R +V QD
Sbjct: 65 SGYELPLCPGHEFSGTVVEVGSGVTSVKPGDRVAVEATSHCSDRSRYKDTVAQDLGLCMA 124
Query: 355 T*SSAPR----------PQLHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHAC 504
S +P G Y + D KLPD + + GAL+EP++V HA
Sbjct: 125 CQSGSPNCCASLSFCGLGGASGGFAEYVVYGEDHMVKLPDSIPDDIGALVEPISVAWHAV 184
Query: 505 KRA 513
+RA
Sbjct: 185 ERA 187
Score = 37.9 bits (84), Expect = 0.21
Identities = 37/148 (25%), Positives = 57/148 (38%), Gaps = 14/148 (9%)
Frame = +3
Query: 255 VKNLTVGDRVAIEPGVPC----RY----------CEFCKTGRYHLCPDMIFCATPPVTRK 392
V ++ GDRVA+E C RY C C++G + C + FC +
Sbjct: 88 VTSVKPGDRVAVEATSHCSDRSRYKDTVAQDLGLCMACQSGSPNCCASLSFCGLGGASGG 147
Query: 393 PRQILQARSRFLLQAS*SRDHGRRSATGAPRGGHSRVQEGGVSAGHVVLVLGAGPIGLLT 572
+ + +++ S + V+ G LVLG GPIGL T
Sbjct: 148 FAEYVVYGEDHMVKLPDSIPDDIGALVEPISVAWHAVERARFQPGQTALVLGGGPIGLAT 207
Query: 573 MLTAKAFGAHKVLIIDILQSRLDFAKSL 656
+L + A K++ + R FAK L
Sbjct: 208 ILALQGHHAGKIVCSEPALIRRQFAKEL 235
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 718,301,669
Number of Sequences: 1657284
Number of extensions: 15402248
Number of successful extensions: 63177
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 56071
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 62341
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 49586781480
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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