Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= heS00269
(725 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate activ... 49 1e-05
M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate activ... 49 1e-05
M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate activ... 49 1e-05
M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein. 49 1e-05
J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein. 49 1e-05
J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator pr... 49 1e-05
D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator pr... 49 1e-05
CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein. 49 1e-05
BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant Gau... 49 1e-05
BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein. 49 1e-05
BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant Gau... 49 1e-05
BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant Gau... 49 1e-05
BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant Gau... 49 1e-05
AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant Gau... 49 1e-05
AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant Gau... 49 1e-05
AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant Gau... 49 1e-05
AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant prot... 49 1e-05
X57108-1|CAA40392.1| 210|Homo sapiens cerebroside sulfate activ... 48 5e-05
DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein... 35 0.34
BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein. 35 0.34
AK097698-1|BAC05143.1| 241|Homo sapiens protein ( Homo sapiens ... 35 0.34
AY186997-1|AAP12462.1| 1024|Homo sapiens WAMTP1-MAML2 fusion pro... 32 1.8
AY040324-1|AAK93833.1| 1024|Homo sapiens MECT1/MAML2 fusion prot... 32 1.8
AY040322-1|AAK93831.1| 1153|Homo sapiens nuclear transcription f... 32 1.8
AJ972402-1|CAI99884.1| 637|Homo sapiens MLL-MAML2 protein. 32 1.8
AB058722-1|BAB47448.1| 1173|Homo sapiens KIAA1819 protein protein. 32 1.8
J02761-1|AAA60212.1| 381|Homo sapiens pulmonary surfactant-asso... 31 4.2
BC032785-1|AAH32785.1| 381|Homo sapiens surfactant, pulmonary-a... 31 4.2
BC032638-1|AAH32638.1| 411|Homo sapiens methyl-CpG binding doma... 31 5.6
AF120993-1|AAD56597.1| 411|Homo sapiens methyl-CpG binding prot... 31 5.6
AF072242-1|AAC68871.1| 411|Homo sapiens methyl-CpG binding prot... 31 5.6
AF039701-1|AAC18050.1| 200|Homo sapiens antigen NY-CO-41 protein. 31 5.6
AF111162-1|AAD43651.1| 1849|Homo sapiens guanine nucleotide exch... 30 7.3
AF084520-1|AAD38427.1| 1849|Homo sapiens brefeldin A-inhibited g... 30 7.3
AB209324-1|BAD92561.1| 1278|Homo sapiens brefeldin A-inhibited g... 30 7.3
BC050449-1|AAH50449.1| 832|Homo sapiens ARFGEF2 protein protein. 30 9.7
AL121903-1|CAI19614.1| 1785|Homo sapiens ADP-ribosylation factor... 30 9.7
AL049537-1|CAI19320.1| 1785|Homo sapiens ADP-ribosylation factor... 30 9.7
AF084521-1|AAD38428.1| 1785|Homo sapiens brefeldin A-inhibited g... 30 9.7
>M60258-1|AAA36596.1| 526|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 526
Score = 49.2 bits (112), Expect = 1e-05
Identities = 19/33 (57%), Positives = 21/33 (63%)
Frame = +2
Query: 623 PVKHKDQLLGKSRCTWGPSYWCSNFSTGRECNA 721
P HK LLG +C WGPSYWC N T +CNA
Sbjct: 485 PSAHKP-LLGTEKCIWGPSYWCQNTETAAQCNA 516
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 413
G+ +++K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 414 LAASIESACHDIQYPAIAKICKD 482
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/26 (42%), Positives = 14/26 (53%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
+LG CT G + WC N T +C A
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGA 44
>M60257-1|AAA36595.1| 524|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 524
Score = 49.2 bits (112), Expect = 1e-05
Identities = 19/33 (57%), Positives = 21/33 (63%)
Frame = +2
Query: 623 PVKHKDQLLGKSRCTWGPSYWCSNFSTGRECNA 721
P HK LLG +C WGPSYWC N T +CNA
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNTETAAQCNA 514
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 413
G+ +++K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 414 LAASIESACHDIQYPAIAKICKD 482
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/26 (42%), Positives = 14/26 (53%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
+LG CT G + WC N T +C A
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGA 44
>M60255-1|AAA36594.1| 527|Homo sapiens cerebroside sulfate
activator protein protein.
Length = 527
Score = 49.2 bits (112), Expect = 1e-05
Identities = 19/33 (57%), Positives = 21/33 (63%)
Frame = +2
Query: 623 PVKHKDQLLGKSRCTWGPSYWCSNFSTGRECNA 721
P HK LLG +C WGPSYWC N T +CNA
Sbjct: 486 PSAHKP-LLGTEKCIWGPSYWCQNTETAAQCNA 517
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 413
G+ +++K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 414 LAASIESACHDIQYPAIAKICKD 482
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/26 (42%), Positives = 14/26 (53%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
+LG CT G + WC N T +C A
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGA 44
>M32221-1|AAA60303.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 49.2 bits (112), Expect = 1e-05
Identities = 19/33 (57%), Positives = 21/33 (63%)
Frame = +2
Query: 623 PVKHKDQLLGKSRCTWGPSYWCSNFSTGRECNA 721
P HK LLG +C WGPSYWC N T +CNA
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNTETAAQCNA 514
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 413
G+ +++K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 414 LAASIESACHDIQYPAIAKICKD 482
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/26 (42%), Positives = 14/26 (53%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
+LG CT G + WC N T +C A
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGA 44
>J03077-1|AAA52560.1| 524|Homo sapiens GLBA protein.
Length = 524
Score = 49.2 bits (112), Expect = 1e-05
Identities = 19/33 (57%), Positives = 21/33 (63%)
Frame = +2
Query: 623 PVKHKDQLLGKSRCTWGPSYWCSNFSTGRECNA 721
P HK LLG +C WGPSYWC N T +CNA
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNTETAAQCNA 514
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 413
G+ +++K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 414 LAASIESACHDIQYPAIAKICKD 482
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/26 (42%), Positives = 14/26 (53%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
+LG CT G + WC N T +C A
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGA 44
>J03015-1|AAB59494.1| 524|Homo sapiens sphingolipid activator
precursor protein.
Length = 524
Score = 49.2 bits (112), Expect = 1e-05
Identities = 19/33 (57%), Positives = 21/33 (63%)
Frame = +2
Query: 623 PVKHKDQLLGKSRCTWGPSYWCSNFSTGRECNA 721
P HK LLG +C WGPSYWC N T +CNA
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNTETAAQCNA 514
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 413
G+ +++K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 414 LAASIESACHDIQYPAIAKICKD 482
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/26 (42%), Positives = 14/26 (53%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
+LG CT G + WC N T +C A
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGA 44
>D00422-1|BAA00321.1| 527|Homo sapiens sphingolipid activator
proteins protein.
Length = 527
Score = 49.2 bits (112), Expect = 1e-05
Identities = 19/33 (57%), Positives = 21/33 (63%)
Frame = +2
Query: 623 PVKHKDQLLGKSRCTWGPSYWCSNFSTGRECNA 721
P HK LLG +C WGPSYWC N T +CNA
Sbjct: 486 PSAHKP-LLGTEKCIWGPSYWCQNTETAAQCNA 517
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 413
G+ +++K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 414 LAASIESACHDIQYPAIAKICKD 482
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/26 (42%), Positives = 14/26 (53%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
+LG CT G + WC N T +C A
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGA 44
>CR456746-1|CAG33027.1| 524|Homo sapiens PSAP protein.
Length = 524
Score = 49.2 bits (112), Expect = 1e-05
Identities = 19/33 (57%), Positives = 21/33 (63%)
Frame = +2
Query: 623 PVKHKDQLLGKSRCTWGPSYWCSNFSTGRECNA 721
P HK LLG +C WGPSYWC N T +CNA
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNTETAAQCNA 514
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 413
G+ +++K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 414 LAASIESACHDIQYPAIAKICKD 482
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/26 (42%), Positives = 14/26 (53%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
+LG CT G + WC N T +C A
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGA 44
>BT006849-1|AAP35495.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 49.2 bits (112), Expect = 1e-05
Identities = 19/33 (57%), Positives = 21/33 (63%)
Frame = +2
Query: 623 PVKHKDQLLGKSRCTWGPSYWCSNFSTGRECNA 721
P HK LLG +C WGPSYWC N T +CNA
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNTETAAQCNA 514
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 413
G+ +++K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 414 LAASIESACHDIQYPAIAKICKD 482
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/26 (42%), Positives = 14/26 (53%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
+LG CT G + WC N T +C A
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGA 44
>BC091483-1|AAH91483.1| 240|Homo sapiens PSAP protein protein.
Length = 240
Score = 49.2 bits (112), Expect = 1e-05
Identities = 19/33 (57%), Positives = 21/33 (63%)
Frame = +2
Query: 623 PVKHKDQLLGKSRCTWGPSYWCSNFSTGRECNA 721
P HK LLG +C WGPSYWC N T +CNA
Sbjct: 199 PSAHKP-LLGTEKCIWGPSYWCQNTETAAQCNA 230
Score = 33.9 bits (74), Expect = 0.60
Identities = 12/28 (42%), Positives = 18/28 (64%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEK 317
G+ +++K ++CGAV HC TVW K
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNK 55
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/26 (42%), Positives = 14/26 (53%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
+LG CT G + WC N T +C A
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGA 44
>BC007612-1|AAH07612.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 49.2 bits (112), Expect = 1e-05
Identities = 19/33 (57%), Positives = 21/33 (63%)
Frame = +2
Query: 623 PVKHKDQLLGKSRCTWGPSYWCSNFSTGRECNA 721
P HK LLG +C WGPSYWC N T +CNA
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNTETAAQCNA 514
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 413
G+ +++K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 414 LAASIESACHDIQYPAIAKICKD 482
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/26 (42%), Positives = 14/26 (53%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
+LG CT G + WC N T +C A
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGA 44
>BC004275-1|AAH04275.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 49.2 bits (112), Expect = 1e-05
Identities = 19/33 (57%), Positives = 21/33 (63%)
Frame = +2
Query: 623 PVKHKDQLLGKSRCTWGPSYWCSNFSTGRECNA 721
P HK LLG +C WGPSYWC N T +CNA
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNTETAAQCNA 514
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 413
G+ +++K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 414 LAASIESACHDIQYPAIAKICKD 482
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/26 (42%), Positives = 14/26 (53%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
+LG CT G + WC N T +C A
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGA 44
>BC001503-1|AAH01503.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 49.2 bits (112), Expect = 1e-05
Identities = 19/33 (57%), Positives = 21/33 (63%)
Frame = +2
Query: 623 PVKHKDQLLGKSRCTWGPSYWCSNFSTGRECNA 721
P HK LLG +C WGPSYWC N T +CNA
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNTETAAQCNA 514
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 413
G+ +++K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 414 LAASIESACHDIQYPAIAKICKD 482
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/26 (42%), Positives = 14/26 (53%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
+LG CT G + WC N T +C A
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGA 44
>AL731541-2|CAI40837.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 524
Score = 49.2 bits (112), Expect = 1e-05
Identities = 19/33 (57%), Positives = 21/33 (63%)
Frame = +2
Query: 623 PVKHKDQLLGKSRCTWGPSYWCSNFSTGRECNA 721
P HK LLG +C WGPSYWC N T +CNA
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNTETAAQCNA 514
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 413
G+ +++K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 414 LAASIESACHDIQYPAIAKICKD 482
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/26 (42%), Positives = 14/26 (53%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
+LG CT G + WC N T +C A
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGA 44
>AL731541-1|CAI40836.1| 559|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) protein.
Length = 559
Score = 49.2 bits (112), Expect = 1e-05
Identities = 19/33 (57%), Positives = 21/33 (63%)
Frame = +2
Query: 623 PVKHKDQLLGKSRCTWGPSYWCSNFSTGRECNA 721
P HK LLG +C WGPSYWC N T +CNA
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNTETAAQCNA 514
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 413
G+ +++K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 414 LAASIESACHDIQYPAIAKICKD 482
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/26 (42%), Positives = 14/26 (53%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
+LG CT G + WC N T +C A
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGA 44
>AK223290-1|BAD97010.1| 524|Homo sapiens prosaposin (variant
Gaucher disease and variant metachromatic
leukodystrophy) v protein.
Length = 524
Score = 49.2 bits (112), Expect = 1e-05
Identities = 19/33 (57%), Positives = 21/33 (63%)
Frame = +2
Query: 623 PVKHKDQLLGKSRCTWGPSYWCSNFSTGRECNA 721
P HK LLG +C WGPSYWC N T +CNA
Sbjct: 483 PSAHKP-LLGTEKCIWGPSYWCQNTETAAQCNA 514
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 413
G+ +++K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 28 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 85
Query: 414 LAASIESACHDIQYPAIAKICKD 482
+ +E C + P ++ CK+
Sbjct: 86 ILVYLEKTCDWLPKPNMSASCKE 108
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/26 (42%), Positives = 14/26 (53%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
+LG CT G + WC N T +C A
Sbjct: 19 VLGLKECTRGSAVWCQNVKTASDCGA 44
>AB209776-1|BAD93013.1| 530|Homo sapiens prosaposin variant
protein.
Length = 530
Score = 49.2 bits (112), Expect = 1e-05
Identities = 19/33 (57%), Positives = 21/33 (63%)
Frame = +2
Query: 623 PVKHKDQLLGKSRCTWGPSYWCSNFSTGRECNA 721
P HK LLG +C WGPSYWC N T +CNA
Sbjct: 489 PSAHKP-LLGTEKCIWGPSYWCQNTETAAQCNA 520
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEY 413
G+ +++K ++CGAV HC TVW K +I V + +KD EE
Sbjct: 31 GSAVWCQNVKTASDCGAVKHCLQTVWNKPTVKSLPCDICKDVVTAAGDM--LKDNATEEE 88
Query: 414 LAASIESACHDIQYPAIAKICKD 482
+ +E C + P ++ CK+
Sbjct: 89 ILVYLEKTCDWLPKPNMSASCKE 111
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/26 (42%), Positives = 14/26 (53%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
+LG CT G + WC N T +C A
Sbjct: 22 VLGLKECTRGSAVWCQNVKTASDCGA 47
>X57108-1|CAA40392.1| 210|Homo sapiens cerebroside sulfate
activator protein.
Length = 210
Score = 47.6 bits (108), Expect = 5e-05
Identities = 18/32 (56%), Positives = 20/32 (62%)
Frame = +2
Query: 623 PVKHKDQLLGKSRCTWGPSYWCSNFSTGRECN 718
P HK LLG +C WGPSYWC N T +CN
Sbjct: 180 PSAHKP-LLGTEKCIWGPSYWCQNTETAAQCN 210
>DQ991252-1|ABJ55983.1| 521|Homo sapiens prosaposin-like protein 1
protein.
Length = 521
Score = 34.7 bits (76), Expect = 0.34
Identities = 13/28 (46%), Positives = 17/28 (60%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEK 317
G+T + L+ A CGAVG+C VW K
Sbjct: 29 GSTVWCQDLQTAARCGAVGYCQGAVWNK 56
Score = 34.7 bits (76), Expect = 0.34
Identities = 12/26 (46%), Positives = 16/26 (61%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
LLG +C GPS+WC + + CNA
Sbjct: 476 LLGTDQCALGPSFWCRSQEAAKLCNA 501
>BC068579-1|AAH68579.1| 543|Homo sapiens PSAPL1 protein protein.
Length = 543
Score = 34.7 bits (76), Expect = 0.34
Identities = 13/28 (46%), Positives = 17/28 (60%)
Frame = +3
Query: 234 GTTSMVRSLKRGAECGAVGHCTATVWEK 317
G+T + L+ A CGAVG+C VW K
Sbjct: 51 GSTVWCQDLQTAARCGAVGYCQGAVWNK 78
Score = 34.7 bits (76), Expect = 0.34
Identities = 12/26 (46%), Positives = 16/26 (61%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
LLG +C GPS+WC + + CNA
Sbjct: 498 LLGTDQCALGPSFWCRSQEAAKLCNA 523
>AK097698-1|BAC05143.1| 241|Homo sapiens protein ( Homo sapiens
cDNA FLJ40379 fis, clone TESTI2035262, weakly similar to
PROACTIVATOR POLYPEPTIDE PRECURSOR. ).
Length = 241
Score = 34.7 bits (76), Expect = 0.34
Identities = 12/26 (46%), Positives = 16/26 (61%)
Frame = +2
Query: 644 LLGKSRCTWGPSYWCSNFSTGRECNA 721
LLG +C GPS+WC + + CNA
Sbjct: 208 LLGTDQCALGPSFWCRSQEAAKLCNA 233
>AY186997-1|AAP12462.1| 1024|Homo sapiens WAMTP1-MAML2 fusion protein
protein.
Length = 1024
Score = 32.3 bits (70), Expect = 1.8
Identities = 23/73 (31%), Positives = 31/73 (42%)
Frame = -1
Query: 296 TVSNRAAFSPPL*TSHHTCGPLAHSSVLVAQTTNLYNKGSLETVDKQQTCLSSLRM*FKF 117
+V N P L S + P S+V++ T N S E KQQ L+S + F
Sbjct: 797 SVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPT 856
Query: 116 NTPALILALQILK 78
TPA Q L+
Sbjct: 857 GTPAAYTPNQSLQ 869
>AY040324-1|AAK93833.1| 1024|Homo sapiens MECT1/MAML2 fusion protein
protein.
Length = 1024
Score = 32.3 bits (70), Expect = 1.8
Identities = 23/73 (31%), Positives = 31/73 (42%)
Frame = -1
Query: 296 TVSNRAAFSPPL*TSHHTCGPLAHSSVLVAQTTNLYNKGSLETVDKQQTCLSSLRM*FKF 117
+V N P L S + P S+V++ T N S E KQQ L+S + F
Sbjct: 797 SVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPT 856
Query: 116 NTPALILALQILK 78
TPA Q L+
Sbjct: 857 GTPAAYTPNQSLQ 869
>AY040322-1|AAK93831.1| 1153|Homo sapiens nuclear transcription
factor/notch receptor regulator protein.
Length = 1153
Score = 32.3 bits (70), Expect = 1.8
Identities = 23/73 (31%), Positives = 31/73 (42%)
Frame = -1
Query: 296 TVSNRAAFSPPL*TSHHTCGPLAHSSVLVAQTTNLYNKGSLETVDKQQTCLSSLRM*FKF 117
+V N P L S + P S+V++ T N S E KQQ L+S + F
Sbjct: 926 SVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPT 985
Query: 116 NTPALILALQILK 78
TPA Q L+
Sbjct: 986 GTPAAYTPNQSLQ 998
>AJ972402-1|CAI99884.1| 637|Homo sapiens MLL-MAML2 protein.
Length = 637
Score = 32.3 bits (70), Expect = 1.8
Identities = 23/73 (31%), Positives = 31/73 (42%)
Frame = -1
Query: 296 TVSNRAAFSPPL*TSHHTCGPLAHSSVLVAQTTNLYNKGSLETVDKQQTCLSSLRM*FKF 117
+V N P L S + P S+V++ T N S E KQQ L+S + F
Sbjct: 410 SVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPT 469
Query: 116 NTPALILALQILK 78
TPA Q L+
Sbjct: 470 GTPAAYTPNQSLQ 482
>AB058722-1|BAB47448.1| 1173|Homo sapiens KIAA1819 protein protein.
Length = 1173
Score = 32.3 bits (70), Expect = 1.8
Identities = 23/73 (31%), Positives = 31/73 (42%)
Frame = -1
Query: 296 TVSNRAAFSPPL*TSHHTCGPLAHSSVLVAQTTNLYNKGSLETVDKQQTCLSSLRM*FKF 117
+V N P L S + P S+V++ T N S E KQQ L+S + F
Sbjct: 946 SVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPT 1005
Query: 116 NTPALILALQILK 78
TPA Q L+
Sbjct: 1006 GTPAAYTPNQSLQ 1018
>J02761-1|AAA60212.1| 381|Homo sapiens pulmonary
surfactant-associated protein SP-B protein.
Length = 381
Score = 31.1 bits (67), Expect = 4.2
Identities = 25/106 (23%), Positives = 41/106 (38%), Gaps = 1/106 (0%)
Frame = +3
Query: 252 RSLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEYLAASIE 431
+SL++ +C A+GHC VW D E V + K K+ I ++ + +E
Sbjct: 41 QSLEQALQCRALGHCLQEVWGHVGADDLCQECED-IVHILN--KMAKEAIFQDTMRKFLE 97
Query: 432 SACHDIQYPAIAKICKD-NTAHFENYIITFSNRTHRPRQCAKSSAC 566
C+ + + C +F I F N+T C C
Sbjct: 98 QECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLC 143
>BC032785-1|AAH32785.1| 381|Homo sapiens surfactant,
pulmonary-associated protein B protein.
Length = 381
Score = 31.1 bits (67), Expect = 4.2
Identities = 25/106 (23%), Positives = 41/106 (38%), Gaps = 1/106 (0%)
Frame = +3
Query: 252 RSLKRGAECGAVGHCTATVWEKQKPDVSDNEISSKFVKLFRGLKDVKDLINEEYLAASIE 431
+SL++ +C A+GHC VW D E V + K K+ I ++ + +E
Sbjct: 41 QSLEQALQCRALGHCLQEVWGHVGADDLCQECED-IVHILN--KMAKEAIFQDTMRKFLE 97
Query: 432 SACHDIQYPAIAKICKD-NTAHFENYIITFSNRTHRPRQCAKSSAC 566
C+ + + C +F I F N+T C C
Sbjct: 98 QECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLC 143
>BC032638-1|AAH32638.1| 411|Homo sapiens methyl-CpG binding domain
protein 2 protein.
Length = 411
Score = 30.7 bits (66), Expect = 5.6
Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Frame = +3
Query: 309 WEKQKPDVSDNEISSKFVK---LFRGLKDVKDLINEEYLAASIESACHDIQYPAIAKI 473
WEK+ +S ++++ + +K L +GL+ V N+E L +++ SA H P ++
Sbjct: 283 WEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQV 340
>AF120993-1|AAD56597.1| 411|Homo sapiens methyl-CpG binding protein
2 protein.
Length = 411
Score = 30.7 bits (66), Expect = 5.6
Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Frame = +3
Query: 309 WEKQKPDVSDNEISSKFVK---LFRGLKDVKDLINEEYLAASIESACHDIQYPAIAKI 473
WEK+ +S ++++ + +K L +GL+ V N+E L +++ SA H P ++
Sbjct: 283 WEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQV 340
>AF072242-1|AAC68871.1| 411|Homo sapiens methyl-CpG binding protein
MBD2 protein.
Length = 411
Score = 30.7 bits (66), Expect = 5.6
Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Frame = +3
Query: 309 WEKQKPDVSDNEISSKFVK---LFRGLKDVKDLINEEYLAASIESACHDIQYPAIAKI 473
WEK+ +S ++++ + +K L +GL+ V N+E L +++ SA H P ++
Sbjct: 283 WEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQV 340
>AF039701-1|AAC18050.1| 200|Homo sapiens antigen NY-CO-41 protein.
Length = 200
Score = 30.7 bits (66), Expect = 5.6
Identities = 16/58 (27%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Frame = +3
Query: 309 WEKQKPDVSDNEISSKFVK---LFRGLKDVKDLINEEYLAASIESACHDIQYPAIAKI 473
WEK+ +S ++++ + +K L +GL+ V N+E L +++ SA H P ++
Sbjct: 72 WEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQV 129
>AF111162-1|AAD43651.1| 1849|Homo sapiens guanine nucleotide
exchange factor protein.
Length = 1849
Score = 30.3 bits (65), Expect = 7.3
Identities = 14/33 (42%), Positives = 21/33 (63%)
Frame = +3
Query: 324 PDVSDNEISSKFVKLFRGLKDVKDLINEEYLAA 422
P V + +++K+ RG+ D KDL EEYL+A
Sbjct: 841 PQVKNKMTKEQYIKMNRGINDSKDL-PEEYLSA 872
>AF084520-1|AAD38427.1| 1849|Homo sapiens brefeldin A-inhibited
guanine nucleotide-exchange protein 1 protein.
Length = 1849
Score = 30.3 bits (65), Expect = 7.3
Identities = 14/33 (42%), Positives = 21/33 (63%)
Frame = +3
Query: 324 PDVSDNEISSKFVKLFRGLKDVKDLINEEYLAA 422
P V + +++K+ RG+ D KDL EEYL+A
Sbjct: 841 PQVKNKMTKEQYIKMNRGINDSKDL-PEEYLSA 872
>AB209324-1|BAD92561.1| 1278|Homo sapiens brefeldin A-inhibited
guanine nucleotide-exchange protein 1 variant protein.
Length = 1278
Score = 30.3 bits (65), Expect = 7.3
Identities = 14/33 (42%), Positives = 21/33 (63%)
Frame = +3
Query: 324 PDVSDNEISSKFVKLFRGLKDVKDLINEEYLAA 422
P V + +++K+ RG+ D KDL EEYL+A
Sbjct: 319 PQVKNKMTKEQYIKMNRGINDSKDL-PEEYLSA 350
>BC050449-1|AAH50449.1| 832|Homo sapiens ARFGEF2 protein protein.
Length = 832
Score = 29.9 bits (64), Expect = 9.7
Identities = 14/36 (38%), Positives = 22/36 (61%)
Frame = +3
Query: 324 PDVSDNEISSKFVKLFRGLKDVKDLINEEYLAASIE 431
P V + +++K+ RG+ D KDL EEYL++ E
Sbjct: 786 PQVKNKMTKEQYIKMNRGINDSKDL-PEEYLSSIYE 820
>AL121903-1|CAI19614.1| 1785|Homo sapiens ADP-ribosylation factor
guanine nucleotide-exchange factor 2 (brefeldin A-inhib
protein.
Length = 1785
Score = 29.9 bits (64), Expect = 9.7
Identities = 14/36 (38%), Positives = 22/36 (61%)
Frame = +3
Query: 324 PDVSDNEISSKFVKLFRGLKDVKDLINEEYLAASIE 431
P V + +++K+ RG+ D KDL EEYL++ E
Sbjct: 786 PQVKNKMTKEQYIKMNRGINDSKDL-PEEYLSSIYE 820
>AL049537-1|CAI19320.1| 1785|Homo sapiens ADP-ribosylation factor
guanine nucleotide-exchange factor 2 (brefeldin A-inhib
protein.
Length = 1785
Score = 29.9 bits (64), Expect = 9.7
Identities = 14/36 (38%), Positives = 22/36 (61%)
Frame = +3
Query: 324 PDVSDNEISSKFVKLFRGLKDVKDLINEEYLAASIE 431
P V + +++K+ RG+ D KDL EEYL++ E
Sbjct: 786 PQVKNKMTKEQYIKMNRGINDSKDL-PEEYLSSIYE 820
>AF084521-1|AAD38428.1| 1785|Homo sapiens brefeldin A-inhibited
guanine nucleotide-exchange protein 2 protein.
Length = 1785
Score = 29.9 bits (64), Expect = 9.7
Identities = 14/36 (38%), Positives = 22/36 (61%)
Frame = +3
Query: 324 PDVSDNEISSKFVKLFRGLKDVKDLINEEYLAASIE 431
P V + +++K+ RG+ D KDL EEYL++ E
Sbjct: 786 PQVKNKMTKEQYIKMNRGINDSKDL-PEEYLSSIYE 820
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 107,463,421
Number of Sequences: 237096
Number of extensions: 2308996
Number of successful extensions: 6060
Number of sequences better than 10.0: 39
Number of HSP's better than 10.0 without gapping: 5642
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6041
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8567175942
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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