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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= heS00241
         (753 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

U59151-1|AAB94299.1|  514|Homo sapiens Cbf5p homolog protein.         153   5e-37
BC010015-1|AAH10015.1|  514|Homo sapiens dyskeratosis congenita ...   153   5e-37
BC009928-1|AAH09928.1|  514|Homo sapiens dyskeratosis congenita ...   153   5e-37
AJ224481-1|CAA11970.1|  514|Homo sapiens dyskerin protein.            153   5e-37
AJ010395-1|CAB51168.1|  524|Homo sapiens dyskerin protein.            153   5e-37
AF067023-1|AAD20232.1|  514|Homo sapiens dyskerin protein.            153   5e-37
AF067008-1|AAD11815.1|  514|Homo sapiens dyskerin protein.            153   5e-37

>U59151-1|AAB94299.1|  514|Homo sapiens Cbf5p homolog protein.
          Length = 514

 Score =  153 bits (372), Expect = 5e-37
 Identities = 66/85 (77%), Positives = 78/85 (91%)
 Frame = +2

Query: 257 VKKLDTAYWPLLLKNFDRLNVRTNHYTPLPFGNSPLKRPISDYVKSGFINVDKPSNPSSH 436
           V KLDT+ WPLLLKNFD+LNVRT HYTPL  G++PLKR I DY+++GFIN+DKPSNPSSH
Sbjct: 44  VAKLDTSQWPLLLKNFDKLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSH 103

Query: 437 EVVSWIKRILKVEKTGHSGTLDPKL 511
           EVV+WI+RIL+VEKTGHSGTLDPK+
Sbjct: 104 EVVAWIRRILRVEKTGHSGTLDPKV 128



 Score = 86.6 bits (205), Expect = 8e-17
 Identities = 39/60 (65%), Positives = 50/60 (83%)
 Frame = +1

Query: 505 EITGCLIVCIDRATRLVKSQQNAGKEYVAVFNLHSAVENIQKVTQGLEKLRGALFQRPRL 684
           ++TGCLIVCI+RATRLVKSQQ+AGKEYV +  LH+A+E   ++++ LE L GALFQRP L
Sbjct: 127 KVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGALFQRPPL 186



 Score = 43.6 bits (98), Expect = 8e-04
 Identities = 17/24 (70%), Positives = 24/24 (100%)
 Frame = +3

Query: 678 PLISAVKRQLRVRTVYDSKLLDFD 749
           PLI+AVKRQLRVRT+Y+SK++++D
Sbjct: 185 PLIAAVKRQLRVRTIYESKMIEYD 208


>BC010015-1|AAH10015.1|  514|Homo sapiens dyskeratosis congenita 1,
           dyskerin protein.
          Length = 514

 Score =  153 bits (372), Expect = 5e-37
 Identities = 66/85 (77%), Positives = 78/85 (91%)
 Frame = +2

Query: 257 VKKLDTAYWPLLLKNFDRLNVRTNHYTPLPFGNSPLKRPISDYVKSGFINVDKPSNPSSH 436
           V KLDT+ WPLLLKNFD+LNVRT HYTPL  G++PLKR I DY+++GFIN+DKPSNPSSH
Sbjct: 44  VAKLDTSQWPLLLKNFDKLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSH 103

Query: 437 EVVSWIKRILKVEKTGHSGTLDPKL 511
           EVV+WI+RIL+VEKTGHSGTLDPK+
Sbjct: 104 EVVAWIRRILRVEKTGHSGTLDPKV 128



 Score = 86.6 bits (205), Expect = 8e-17
 Identities = 39/60 (65%), Positives = 50/60 (83%)
 Frame = +1

Query: 505 EITGCLIVCIDRATRLVKSQQNAGKEYVAVFNLHSAVENIQKVTQGLEKLRGALFQRPRL 684
           ++TGCLIVCI+RATRLVKSQQ+AGKEYV +  LH+A+E   ++++ LE L GALFQRP L
Sbjct: 127 KVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGALFQRPPL 186



 Score = 43.6 bits (98), Expect = 8e-04
 Identities = 17/24 (70%), Positives = 24/24 (100%)
 Frame = +3

Query: 678 PLISAVKRQLRVRTVYDSKLLDFD 749
           PLI+AVKRQLRVRT+Y+SK++++D
Sbjct: 185 PLIAAVKRQLRVRTIYESKMIEYD 208


>BC009928-1|AAH09928.1|  514|Homo sapiens dyskeratosis congenita 1,
           dyskerin protein.
          Length = 514

 Score =  153 bits (372), Expect = 5e-37
 Identities = 66/85 (77%), Positives = 78/85 (91%)
 Frame = +2

Query: 257 VKKLDTAYWPLLLKNFDRLNVRTNHYTPLPFGNSPLKRPISDYVKSGFINVDKPSNPSSH 436
           V KLDT+ WPLLLKNFD+LNVRT HYTPL  G++PLKR I DY+++GFIN+DKPSNPSSH
Sbjct: 44  VAKLDTSQWPLLLKNFDKLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSH 103

Query: 437 EVVSWIKRILKVEKTGHSGTLDPKL 511
           EVV+WI+RIL+VEKTGHSGTLDPK+
Sbjct: 104 EVVAWIRRILRVEKTGHSGTLDPKV 128



 Score = 86.6 bits (205), Expect = 8e-17
 Identities = 39/60 (65%), Positives = 50/60 (83%)
 Frame = +1

Query: 505 EITGCLIVCIDRATRLVKSQQNAGKEYVAVFNLHSAVENIQKVTQGLEKLRGALFQRPRL 684
           ++TGCLIVCI+RATRLVKSQQ+AGKEYV +  LH+A+E   ++++ LE L GALFQRP L
Sbjct: 127 KVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGALFQRPPL 186



 Score = 43.6 bits (98), Expect = 8e-04
 Identities = 17/24 (70%), Positives = 24/24 (100%)
 Frame = +3

Query: 678 PLISAVKRQLRVRTVYDSKLLDFD 749
           PLI+AVKRQLRVRT+Y+SK++++D
Sbjct: 185 PLIAAVKRQLRVRTIYESKMIEYD 208


>AJ224481-1|CAA11970.1|  514|Homo sapiens dyskerin protein.
          Length = 514

 Score =  153 bits (372), Expect = 5e-37
 Identities = 66/85 (77%), Positives = 78/85 (91%)
 Frame = +2

Query: 257 VKKLDTAYWPLLLKNFDRLNVRTNHYTPLPFGNSPLKRPISDYVKSGFINVDKPSNPSSH 436
           V KLDT+ WPLLLKNFD+LNVRT HYTPL  G++PLKR I DY+++GFIN+DKPSNPSSH
Sbjct: 44  VAKLDTSQWPLLLKNFDKLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSH 103

Query: 437 EVVSWIKRILKVEKTGHSGTLDPKL 511
           EVV+WI+RIL+VEKTGHSGTLDPK+
Sbjct: 104 EVVAWIRRILRVEKTGHSGTLDPKV 128



 Score = 86.6 bits (205), Expect = 8e-17
 Identities = 39/60 (65%), Positives = 50/60 (83%)
 Frame = +1

Query: 505 EITGCLIVCIDRATRLVKSQQNAGKEYVAVFNLHSAVENIQKVTQGLEKLRGALFQRPRL 684
           ++TGCLIVCI+RATRLVKSQQ+AGKEYV +  LH+A+E   ++++ LE L GALFQRP L
Sbjct: 127 KVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGALFQRPPL 186



 Score = 43.6 bits (98), Expect = 8e-04
 Identities = 17/24 (70%), Positives = 24/24 (100%)
 Frame = +3

Query: 678 PLISAVKRQLRVRTVYDSKLLDFD 749
           PLI+AVKRQLRVRT+Y+SK++++D
Sbjct: 185 PLIAAVKRQLRVRTIYESKMIEYD 208


>AJ010395-1|CAB51168.1|  524|Homo sapiens dyskerin protein.
          Length = 524

 Score =  153 bits (372), Expect = 5e-37
 Identities = 66/85 (77%), Positives = 78/85 (91%)
 Frame = +2

Query: 257 VKKLDTAYWPLLLKNFDRLNVRTNHYTPLPFGNSPLKRPISDYVKSGFINVDKPSNPSSH 436
           V KLDT+ WPLLLKNFD+LNVRT HYTPL  G++PLKR I DY+++GFIN+DKPSNPSSH
Sbjct: 44  VAKLDTSQWPLLLKNFDKLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSH 103

Query: 437 EVVSWIKRILKVEKTGHSGTLDPKL 511
           EVV+WI+RIL+VEKTGHSGTLDPK+
Sbjct: 104 EVVAWIRRILRVEKTGHSGTLDPKV 128



 Score = 86.6 bits (205), Expect = 8e-17
 Identities = 39/60 (65%), Positives = 50/60 (83%)
 Frame = +1

Query: 505 EITGCLIVCIDRATRLVKSQQNAGKEYVAVFNLHSAVENIQKVTQGLEKLRGALFQRPRL 684
           ++TGCLIVCI+RATRLVKSQQ+AGKEYV +  LH+A+E   ++++ LE L GALFQRP L
Sbjct: 127 KVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGALFQRPPL 186



 Score = 43.6 bits (98), Expect = 8e-04
 Identities = 17/24 (70%), Positives = 24/24 (100%)
 Frame = +3

Query: 678 PLISAVKRQLRVRTVYDSKLLDFD 749
           PLI+AVKRQLRVRT+Y+SK++++D
Sbjct: 185 PLIAAVKRQLRVRTIYESKMIEYD 208


>AF067023-1|AAD20232.1|  514|Homo sapiens dyskerin protein.
          Length = 514

 Score =  153 bits (372), Expect = 5e-37
 Identities = 66/85 (77%), Positives = 78/85 (91%)
 Frame = +2

Query: 257 VKKLDTAYWPLLLKNFDRLNVRTNHYTPLPFGNSPLKRPISDYVKSGFINVDKPSNPSSH 436
           V KLDT+ WPLLLKNFD+LNVRT HYTPL  G++PLKR I DY+++GFIN+DKPSNPSSH
Sbjct: 44  VAKLDTSQWPLLLKNFDKLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSH 103

Query: 437 EVVSWIKRILKVEKTGHSGTLDPKL 511
           EVV+WI+RIL+VEKTGHSGTLDPK+
Sbjct: 104 EVVAWIRRILRVEKTGHSGTLDPKV 128



 Score = 86.6 bits (205), Expect = 8e-17
 Identities = 39/60 (65%), Positives = 50/60 (83%)
 Frame = +1

Query: 505 EITGCLIVCIDRATRLVKSQQNAGKEYVAVFNLHSAVENIQKVTQGLEKLRGALFQRPRL 684
           ++TGCLIVCI+RATRLVKSQQ+AGKEYV +  LH+A+E   ++++ LE L GALFQRP L
Sbjct: 127 KVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGALFQRPPL 186



 Score = 43.6 bits (98), Expect = 8e-04
 Identities = 17/24 (70%), Positives = 24/24 (100%)
 Frame = +3

Query: 678 PLISAVKRQLRVRTVYDSKLLDFD 749
           PLI+AVKRQLRVRT+Y+SK++++D
Sbjct: 185 PLIAAVKRQLRVRTIYESKMIEYD 208


>AF067008-1|AAD11815.1|  514|Homo sapiens dyskerin protein.
          Length = 514

 Score =  153 bits (372), Expect = 5e-37
 Identities = 66/85 (77%), Positives = 78/85 (91%)
 Frame = +2

Query: 257 VKKLDTAYWPLLLKNFDRLNVRTNHYTPLPFGNSPLKRPISDYVKSGFINVDKPSNPSSH 436
           V KLDT+ WPLLLKNFD+LNVRT HYTPL  G++PLKR I DY+++GFIN+DKPSNPSSH
Sbjct: 44  VAKLDTSQWPLLLKNFDKLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSH 103

Query: 437 EVVSWIKRILKVEKTGHSGTLDPKL 511
           EVV+WI+RIL+VEKTGHSGTLDPK+
Sbjct: 104 EVVAWIRRILRVEKTGHSGTLDPKV 128



 Score = 86.6 bits (205), Expect = 8e-17
 Identities = 39/60 (65%), Positives = 50/60 (83%)
 Frame = +1

Query: 505 EITGCLIVCIDRATRLVKSQQNAGKEYVAVFNLHSAVENIQKVTQGLEKLRGALFQRPRL 684
           ++TGCLIVCI+RATRLVKSQQ+AGKEYV +  LH+A+E   ++++ LE L GALFQRP L
Sbjct: 127 KVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGALFQRPPL 186



 Score = 43.6 bits (98), Expect = 8e-04
 Identities = 17/24 (70%), Positives = 24/24 (100%)
 Frame = +3

Query: 678 PLISAVKRQLRVRTVYDSKLLDFD 749
           PLI+AVKRQLRVRT+Y+SK++++D
Sbjct: 185 PLIAAVKRQLRVRTIYESKMIEYD 208


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,670,270
Number of Sequences: 237096
Number of extensions: 2202240
Number of successful extensions: 8300
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 8161
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8300
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9071127468
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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