Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= heS00175
(682 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X79440-1|CAA55956.1| 604|Homo sapiens malate dehydrogenase (oxa... 180 6e-45
BC022472-1|AAH22472.1| 604|Homo sapiens malic enzyme 3, NADP(+)... 180 6e-45
AY424278-1|AAR04784.1| 259|Homo sapiens mitochondrial NADP(+)-d... 163 4e-40
AK092181-1|BAC03822.1| 252|Homo sapiens protein ( Homo sapiens ... 163 4e-40
X77244-1|CAA54460.1| 572|Homo sapiens malate dehydrogenase (oxa... 126 1e-28
U43944-1|AAC50613.1| 565|Homo sapiens cytosolic NADP(+)-depende... 126 1e-28
L34035-1|AAB01380.1| 572|Homo sapiens NADP-dependent malic enzy... 126 1e-28
BC025246-1|AAH25246.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 126 1e-28
AL391416-2|CAH73129.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 126 1e-28
AL136970-1|CAC19505.2| 572|Homo sapiens malic enzyme 1, NADP(+)... 126 1e-28
AL049699-1|CAI22634.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 126 1e-28
AK223417-1|BAD97137.1| 572|Homo sapiens cytosolic malic enzyme ... 126 1e-28
M55905-1|AAA36197.1| 584|Homo sapiens mitochondrial NAD(P)+ -de... 118 3e-26
BC000147-1|AAH00147.1| 479|Homo sapiens ME2 protein protein. 118 3e-26
AF404758-1|AAK95642.1| 569|Homo sapiens NYD-SP12 protein. 31 3.8
AF345909-1|AAK29063.2| 569|Homo sapiens NYD-SP12 protein. 31 3.8
BC034496-1|AAH34496.1| 569|Homo sapiens spermatogenesis associa... 30 8.8
AF151875-1|AAD34112.1| 178|Homo sapiens CGI-117 protein protein. 30 8.8
>X79440-1|CAA55956.1| 604|Homo sapiens malate dehydrogenase
(oxaloacetate decarboxylating) (NADP+) protein.
Length = 604
Score = 180 bits (437), Expect = 6e-45
Identities = 104/222 (46%), Positives = 133/222 (59%), Gaps = 7/222 (3%)
Frame = +2
Query: 38 ENPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFI 217
++ L+KYI LM L DRNE LFYR + +V + MPIVYTPTVGLACQ +GL +RRPRGLFI
Sbjct: 101 QSDLDKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFI 160
Query: 218 TIHDKGHVYDVLRT-GRRRTSAPLL*PTENV-----FWAWAISARAGWASLW-ANSRSTP 376
TIHDKGH+ +L + A ++ E + + + G +L+ A P
Sbjct: 161 TIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNP 220
Query: 377 RSEASSLISVYPSLSTWVRSPSRCWTTRCTSGSGSGACWPRLRRLLDEFMRAVVRRYGQN 556
+ L+ V + +R P G + L LDEFM+AV ++G N
Sbjct: 221 QQCLPVLLDVGTNNEELLRDPLYIGLKH---QRVHGKAYDDL---LDEFMQAVTDKFGIN 274
Query: 557 CLVQFEDFGNANAFRLLEKYMNKYCTFNDDIQGTAAVAVAGL 682
CL+QFEDF NANAFRLL KY NKYC FNDDIQGTA+VAVAG+
Sbjct: 275 CLIQFEDFANANAFRLLNKYRNKYCMFNDDIQGTASVAVAGI 316
Score = 124 bits (300), Expect = 2e-28
Identities = 53/78 (67%), Positives = 65/78 (83%)
Frame = +1
Query: 256 NWPETDVRAIVVTDGERILGLGDFGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTI 435
+WPE +++A+VVTDGERILGLGD G GMGIPVGKLALYTA GG+ P QCLP+ +DVGT
Sbjct: 174 SWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTN 233
Query: 436 TQSMLDDPLYIGLRQRRV 489
+ +L DPLYIGL+ +RV
Sbjct: 234 NEELLRDPLYIGLKHQRV 251
>BC022472-1|AAH22472.1| 604|Homo sapiens malic enzyme 3,
NADP(+)-dependent, mitochondrial protein.
Length = 604
Score = 180 bits (437), Expect = 6e-45
Identities = 104/222 (46%), Positives = 133/222 (59%), Gaps = 7/222 (3%)
Frame = +2
Query: 38 ENPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFI 217
++ L+KYI LM L DRNE LFYR + +V + MPIVYTPTVGLACQ +GL +RRPRGLFI
Sbjct: 101 QSDLDKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFI 160
Query: 218 TIHDKGHVYDVLRT-GRRRTSAPLL*PTENV-----FWAWAISARAGWASLW-ANSRSTP 376
TIHDKGH+ +L + A ++ E + + + G +L+ A P
Sbjct: 161 TIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNP 220
Query: 377 RSEASSLISVYPSLSTWVRSPSRCWTTRCTSGSGSGACWPRLRRLLDEFMRAVVRRYGQN 556
+ L+ V + +R P G + L LDEFM+AV ++G N
Sbjct: 221 QQCLPVLLDVGTNNEELLRDPLYIGLKH---QRVHGKAYDDL---LDEFMQAVTDKFGIN 274
Query: 557 CLVQFEDFGNANAFRLLEKYMNKYCTFNDDIQGTAAVAVAGL 682
CL+QFEDF NANAFRLL KY NKYC FNDDIQGTA+VAVAG+
Sbjct: 275 CLIQFEDFANANAFRLLNKYRNKYCMFNDDIQGTASVAVAGI 316
Score = 124 bits (300), Expect = 2e-28
Identities = 53/78 (67%), Positives = 65/78 (83%)
Frame = +1
Query: 256 NWPETDVRAIVVTDGERILGLGDFGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTI 435
+WPE +++A+VVTDGERILGLGD G GMGIPVGKLALYTA GG+ P QCLP+ +DVGT
Sbjct: 174 SWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTN 233
Query: 436 TQSMLDDPLYIGLRQRRV 489
+ +L DPLYIGL+ +RV
Sbjct: 234 NEELLRDPLYIGLKHQRV 251
>AY424278-1|AAR04784.1| 259|Homo sapiens mitochondrial
NADP(+)-dependent malic enzyme 3 protein.
Length = 259
Score = 163 bits (397), Expect = 4e-40
Identities = 96/212 (45%), Positives = 123/212 (58%), Gaps = 7/212 (3%)
Frame = +2
Query: 38 ENPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFI 217
++ L+KYI LM L DRNE LFYR + +V + MPIVYTPTVGLACQ +GL +RRPRGLFI
Sbjct: 39 QSDLDKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFI 98
Query: 218 TIHDKGHVYDVLRT-GRRRTSAPLL*PTENV-----FWAWAISARAGWASLW-ANSRSTP 376
TIHDKGH+ +L + A ++ E + + + G +L+ A P
Sbjct: 99 TIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNP 158
Query: 377 RSEASSLISVYPSLSTWVRSPSRCWTTRCTSGSGSGACWPRLRRLLDEFMRAVVRRYGQN 556
+ L+ V + +R P G + L LDEFM+AV ++G N
Sbjct: 159 QQCLPVLLDVGTNNEELLRDPLYIGLKH---QRVHGKAYDDL---LDEFMQAVTDKFGIN 212
Query: 557 CLVQFEDFGNANAFRLLEKYMNKYCTFNDDIQ 652
CL+QFEDF NANAFRLL KY NKYC FNDDIQ
Sbjct: 213 CLIQFEDFANANAFRLLNKYRNKYCMFNDDIQ 244
Score = 124 bits (300), Expect = 2e-28
Identities = 53/78 (67%), Positives = 65/78 (83%)
Frame = +1
Query: 256 NWPETDVRAIVVTDGERILGLGDFGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTI 435
+WPE +++A+VVTDGERILGLGD G GMGIPVGKLALYTA GG+ P QCLP+ +DVGT
Sbjct: 112 SWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTN 171
Query: 436 TQSMLDDPLYIGLRQRRV 489
+ +L DPLYIGL+ +RV
Sbjct: 172 NEELLRDPLYIGLKHQRV 189
>AK092181-1|BAC03822.1| 252|Homo sapiens protein ( Homo sapiens
cDNA FLJ34862 fis, clone NT2NE2013547, highly similar to
NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL PRECURSOR (EC
1.1.1.40). ).
Length = 252
Score = 163 bits (397), Expect = 4e-40
Identities = 96/212 (45%), Positives = 123/212 (58%), Gaps = 7/212 (3%)
Frame = +2
Query: 38 ENPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFI 217
++ L+KYI LM L DRNE LFYR + +V + MPIVYTPTVGLACQ +GL +RRPRGLFI
Sbjct: 39 QSDLDKYIILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFI 98
Query: 218 TIHDKGHVYDVLRT-GRRRTSAPLL*PTENV-----FWAWAISARAGWASLW-ANSRSTP 376
TIHDKGH+ +L + A ++ E + + + G +L+ A P
Sbjct: 99 TIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNP 158
Query: 377 RSEASSLISVYPSLSTWVRSPSRCWTTRCTSGSGSGACWPRLRRLLDEFMRAVVRRYGQN 556
+ L+ V + +R P G + L LDEFM+AV ++G N
Sbjct: 159 QQCLPVLLDVGTNNEELLRDPLYIGLKH---QRVHGKAYDDL---LDEFMQAVTDKFGIN 212
Query: 557 CLVQFEDFGNANAFRLLEKYMNKYCTFNDDIQ 652
CL+QFEDF NANAFRLL KY NKYC FNDDIQ
Sbjct: 213 CLIQFEDFANANAFRLLNKYRNKYCMFNDDIQ 244
Score = 124 bits (300), Expect = 2e-28
Identities = 53/78 (67%), Positives = 65/78 (83%)
Frame = +1
Query: 256 NWPETDVRAIVVTDGERILGLGDFGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTI 435
+WPE +++A+VVTDGERILGLGD G GMGIPVGKLALYTA GG+ P QCLP+ +DVGT
Sbjct: 112 SWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTN 171
Query: 436 TQSMLDDPLYIGLRQRRV 489
+ +L DPLYIGL+ +RV
Sbjct: 172 NEELLRDPLYIGLKHQRV 189
>X77244-1|CAA54460.1| 572|Homo sapiens malate dehydrogenase
(oxaloacetate decarboxylating) (NADP+) protein.
Length = 572
Score = 126 bits (303), Expect = 1e-28
Identities = 56/77 (72%), Positives = 64/77 (83%)
Frame = +1
Query: 259 WPETDVRAIVVTDGERILGLGDFGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTIT 438
WPE ++AIVVTDGERILGLGD G GMGIPVGKLALYTA GG+ P +CLP+ +DVGT
Sbjct: 140 WPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTEN 199
Query: 439 QSMLDDPLYIGLRQRRV 489
+ +L DPLYIGLRQRRV
Sbjct: 200 EELLKDPLYIGLRQRRV 216
Score = 103 bits (246), Expect = 8e-22
Identities = 43/68 (63%), Positives = 56/68 (82%)
Frame = +2
Query: 50 NKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHD 229
++Y+ LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD
Sbjct: 70 DRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHD 129
Query: 230 KGHVYDVL 253
+GH+ VL
Sbjct: 130 RGHIASVL 137
Score = 102 bits (245), Expect = 1e-21
Identities = 45/57 (78%), Positives = 49/57 (85%)
Frame = +2
Query: 512 LDEFMRAVVRRYGQNCLVQFEDFGNANAFRLLEKYMNKYCTFNDDIQGTAAVAVAGL 682
LDEFM AV +YG NCL+QFEDF N NAFRLL KY N+YCTFNDDIQGTA+VAVAGL
Sbjct: 225 LDEFMEAVSSKYGMNCLIQFEDFANVNAFRLLNKYRNQYCTFNDDIQGTASVAVAGL 281
>U43944-1|AAC50613.1| 565|Homo sapiens cytosolic NADP(+)-dependent
malic enzyme protein.
Length = 565
Score = 126 bits (303), Expect = 1e-28
Identities = 56/77 (72%), Positives = 64/77 (83%)
Frame = +1
Query: 259 WPETDVRAIVVTDGERILGLGDFGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTIT 438
WPE ++AIVVTDGERILGLGD G GMGIPVGKLALYTA GG+ P +CLP+ +DVGT
Sbjct: 133 WPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTEN 192
Query: 439 QSMLDDPLYIGLRQRRV 489
+ +L DPLYIGLRQRRV
Sbjct: 193 EELLKDPLYIGLRQRRV 209
Score = 103 bits (246), Expect = 8e-22
Identities = 43/68 (63%), Positives = 56/68 (82%)
Frame = +2
Query: 50 NKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHD 229
++Y+ LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD
Sbjct: 63 DRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHD 122
Query: 230 KGHVYDVL 253
+GH+ VL
Sbjct: 123 RGHIASVL 130
Score = 102 bits (245), Expect = 1e-21
Identities = 45/57 (78%), Positives = 49/57 (85%)
Frame = +2
Query: 512 LDEFMRAVVRRYGQNCLVQFEDFGNANAFRLLEKYMNKYCTFNDDIQGTAAVAVAGL 682
LDEFM AV +YG NCL+QFEDF N NAFRLL KY N+YCTFNDDIQGTA+VAVAGL
Sbjct: 218 LDEFMEAVSSKYGMNCLIQFEDFANVNAFRLLNKYRNQYCTFNDDIQGTASVAVAGL 274
>L34035-1|AAB01380.1| 572|Homo sapiens NADP-dependent malic enzyme
protein.
Length = 572
Score = 126 bits (303), Expect = 1e-28
Identities = 56/77 (72%), Positives = 64/77 (83%)
Frame = +1
Query: 259 WPETDVRAIVVTDGERILGLGDFGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTIT 438
WPE ++AIVVTDGERILGLGD G GMGIPVGKLALYTA GG+ P +CLP+ +DVGT
Sbjct: 140 WPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTEN 199
Query: 439 QSMLDDPLYIGLRQRRV 489
+ +L DPLYIGLRQRRV
Sbjct: 200 EELLKDPLYIGLRQRRV 216
Score = 103 bits (246), Expect = 8e-22
Identities = 43/68 (63%), Positives = 56/68 (82%)
Frame = +2
Query: 50 NKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHD 229
++Y+ LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD
Sbjct: 70 DRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHD 129
Query: 230 KGHVYDVL 253
+GH+ VL
Sbjct: 130 RGHIASVL 137
Score = 102 bits (245), Expect = 1e-21
Identities = 45/57 (78%), Positives = 49/57 (85%)
Frame = +2
Query: 512 LDEFMRAVVRRYGQNCLVQFEDFGNANAFRLLEKYMNKYCTFNDDIQGTAAVAVAGL 682
LDEFM AV +YG NCL+QFEDF N NAFRLL KY N+YCTFNDDIQGTA+VAVAGL
Sbjct: 225 LDEFMEAVSSKYGMNCLIQFEDFANVNAFRLLNKYRNQYCTFNDDIQGTASVAVAGL 281
>BC025246-1|AAH25246.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 126 bits (303), Expect = 1e-28
Identities = 56/77 (72%), Positives = 64/77 (83%)
Frame = +1
Query: 259 WPETDVRAIVVTDGERILGLGDFGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTIT 438
WPE ++AIVVTDGERILGLGD G GMGIPVGKLALYTA GG+ P +CLP+ +DVGT
Sbjct: 140 WPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTEN 199
Query: 439 QSMLDDPLYIGLRQRRV 489
+ +L DPLYIGLRQRRV
Sbjct: 200 EELLKDPLYIGLRQRRV 216
Score = 103 bits (246), Expect = 8e-22
Identities = 43/68 (63%), Positives = 56/68 (82%)
Frame = +2
Query: 50 NKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHD 229
++Y+ LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD
Sbjct: 70 DRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHD 129
Query: 230 KGHVYDVL 253
+GH+ VL
Sbjct: 130 RGHIASVL 137
Score = 102 bits (245), Expect = 1e-21
Identities = 45/57 (78%), Positives = 49/57 (85%)
Frame = +2
Query: 512 LDEFMRAVVRRYGQNCLVQFEDFGNANAFRLLEKYMNKYCTFNDDIQGTAAVAVAGL 682
LDEFM AV +YG NCL+QFEDF N NAFRLL KY N+YCTFNDDIQGTA+VAVAGL
Sbjct: 225 LDEFMEAVSSKYGMNCLIQFEDFANVNAFRLLNKYRNQYCTFNDDIQGTASVAVAGL 281
>AL391416-2|CAH73129.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 126 bits (303), Expect = 1e-28
Identities = 56/77 (72%), Positives = 64/77 (83%)
Frame = +1
Query: 259 WPETDVRAIVVTDGERILGLGDFGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTIT 438
WPE ++AIVVTDGERILGLGD G GMGIPVGKLALYTA GG+ P +CLP+ +DVGT
Sbjct: 140 WPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTEN 199
Query: 439 QSMLDDPLYIGLRQRRV 489
+ +L DPLYIGLRQRRV
Sbjct: 200 EELLKDPLYIGLRQRRV 216
Score = 103 bits (246), Expect = 8e-22
Identities = 43/68 (63%), Positives = 56/68 (82%)
Frame = +2
Query: 50 NKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHD 229
++Y+ LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD
Sbjct: 70 DRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHD 129
Query: 230 KGHVYDVL 253
+GH+ VL
Sbjct: 130 RGHIASVL 137
Score = 102 bits (245), Expect = 1e-21
Identities = 45/57 (78%), Positives = 49/57 (85%)
Frame = +2
Query: 512 LDEFMRAVVRRYGQNCLVQFEDFGNANAFRLLEKYMNKYCTFNDDIQGTAAVAVAGL 682
LDEFM AV +YG NCL+QFEDF N NAFRLL KY N+YCTFNDDIQGTA+VAVAGL
Sbjct: 225 LDEFMEAVSSKYGMNCLIQFEDFANVNAFRLLNKYRNQYCTFNDDIQGTASVAVAGL 281
>AL136970-1|CAC19505.2| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 126 bits (303), Expect = 1e-28
Identities = 56/77 (72%), Positives = 64/77 (83%)
Frame = +1
Query: 259 WPETDVRAIVVTDGERILGLGDFGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTIT 438
WPE ++AIVVTDGERILGLGD G GMGIPVGKLALYTA GG+ P +CLP+ +DVGT
Sbjct: 140 WPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTEN 199
Query: 439 QSMLDDPLYIGLRQRRV 489
+ +L DPLYIGLRQRRV
Sbjct: 200 EELLKDPLYIGLRQRRV 216
Score = 103 bits (246), Expect = 8e-22
Identities = 43/68 (63%), Positives = 56/68 (82%)
Frame = +2
Query: 50 NKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHD 229
++Y+ LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD
Sbjct: 70 DRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHD 129
Query: 230 KGHVYDVL 253
+GH+ VL
Sbjct: 130 RGHIASVL 137
Score = 102 bits (245), Expect = 1e-21
Identities = 45/57 (78%), Positives = 49/57 (85%)
Frame = +2
Query: 512 LDEFMRAVVRRYGQNCLVQFEDFGNANAFRLLEKYMNKYCTFNDDIQGTAAVAVAGL 682
LDEFM AV +YG NCL+QFEDF N NAFRLL KY N+YCTFNDDIQGTA+VAVAGL
Sbjct: 225 LDEFMEAVSSKYGMNCLIQFEDFANVNAFRLLNKYRNQYCTFNDDIQGTASVAVAGL 281
>AL049699-1|CAI22634.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 126 bits (303), Expect = 1e-28
Identities = 56/77 (72%), Positives = 64/77 (83%)
Frame = +1
Query: 259 WPETDVRAIVVTDGERILGLGDFGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTIT 438
WPE ++AIVVTDGERILGLGD G GMGIPVGKLALYTA GG+ P +CLP+ +DVGT
Sbjct: 140 WPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTEN 199
Query: 439 QSMLDDPLYIGLRQRRV 489
+ +L DPLYIGLRQRRV
Sbjct: 200 EELLKDPLYIGLRQRRV 216
Score = 103 bits (246), Expect = 8e-22
Identities = 43/68 (63%), Positives = 56/68 (82%)
Frame = +2
Query: 50 NKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHD 229
++Y+ LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD
Sbjct: 70 DRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHD 129
Query: 230 KGHVYDVL 253
+GH+ VL
Sbjct: 130 RGHIASVL 137
Score = 102 bits (245), Expect = 1e-21
Identities = 45/57 (78%), Positives = 49/57 (85%)
Frame = +2
Query: 512 LDEFMRAVVRRYGQNCLVQFEDFGNANAFRLLEKYMNKYCTFNDDIQGTAAVAVAGL 682
LDEFM AV +YG NCL+QFEDF N NAFRLL KY N+YCTFNDDIQGTA+VAVAGL
Sbjct: 225 LDEFMEAVSSKYGMNCLIQFEDFANVNAFRLLNKYRNQYCTFNDDIQGTASVAVAGL 281
>AK223417-1|BAD97137.1| 572|Homo sapiens cytosolic malic enzyme 1
variant protein.
Length = 572
Score = 126 bits (303), Expect = 1e-28
Identities = 56/77 (72%), Positives = 64/77 (83%)
Frame = +1
Query: 259 WPETDVRAIVVTDGERILGLGDFGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTIT 438
WPE ++AIVVTDGERILGLGD G GMGIPVGKLALYTA GG+ P +CLP+ +DVGT
Sbjct: 140 WPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTEN 199
Query: 439 QSMLDDPLYIGLRQRRV 489
+ +L DPLYIGLRQRRV
Sbjct: 200 EELLKDPLYIGLRQRRV 216
Score = 103 bits (246), Expect = 8e-22
Identities = 43/68 (63%), Positives = 56/68 (82%)
Frame = +2
Query: 50 NKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHD 229
++Y+ LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD
Sbjct: 70 DRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHD 129
Query: 230 KGHVYDVL 253
+GH+ VL
Sbjct: 130 RGHIASVL 137
Score = 99.5 bits (237), Expect = 1e-20
Identities = 44/57 (77%), Positives = 48/57 (84%)
Frame = +2
Query: 512 LDEFMRAVVRRYGQNCLVQFEDFGNANAFRLLEKYMNKYCTFNDDIQGTAAVAVAGL 682
LDEFM AV +YG NCL+QFEDF N NAFRLL KY N+YCT NDDIQGTA+VAVAGL
Sbjct: 225 LDEFMEAVSSKYGMNCLIQFEDFANVNAFRLLNKYRNQYCTSNDDIQGTASVAVAGL 281
>M55905-1|AAA36197.1| 584|Homo sapiens mitochondrial NAD(P)+
-dependent malic enzyme protein.
Length = 584
Score = 118 bits (283), Expect = 3e-26
Identities = 52/77 (67%), Positives = 61/77 (79%)
Frame = +1
Query: 256 NWPETDVRAIVVTDGERILGLGDFGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTI 435
NWPE V+A+VVTDGERILGLGD G GMGIPVGKL LYTA GI+P +CLP+ IDVGT
Sbjct: 149 NWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTD 208
Query: 436 TQSMLDDPLYIGLRQRR 486
++L DP Y+GL Q+R
Sbjct: 209 NIALLKDPFYMGLYQKR 225
Score = 105 bits (253), Expect = 1e-22
Identities = 42/71 (59%), Positives = 59/71 (83%)
Frame = +2
Query: 41 NPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFIT 220
+PL KYIY+MG+ +RNE LFYR + D++ +MPIVYTPTVGLAC ++G ++RRP+GLFI+
Sbjct: 77 SPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFIS 136
Query: 221 IHDKGHVYDVL 253
I D+GHV ++
Sbjct: 137 ISDRGHVRSIV 147
Score = 101 bits (241), Expect = 3e-21
Identities = 44/58 (75%), Positives = 50/58 (86%)
Frame = +2
Query: 509 LLDEFMRAVVRRYGQNCLVQFEDFGNANAFRLLEKYMNKYCTFNDDIQGTAAVAVAGL 682
L+DEFM+A+ RYG+N L+QFEDFGN NAFR L KY KYCTFNDDIQGTAAVA+AGL
Sbjct: 234 LIDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGL 291
>BC000147-1|AAH00147.1| 479|Homo sapiens ME2 protein protein.
Length = 479
Score = 118 bits (283), Expect = 3e-26
Identities = 52/77 (67%), Positives = 61/77 (79%)
Frame = +1
Query: 256 NWPETDVRAIVVTDGERILGLGDFGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGTI 435
NWPE V+A+VVTDGERILGLGD G GMGIPVGKL LYTA GI+P +CLP+ IDVGT
Sbjct: 149 NWPENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTD 208
Query: 436 TQSMLDDPLYIGLRQRR 486
++L DP Y+GL Q+R
Sbjct: 209 NIALLKDPFYMGLYQKR 225
Score = 105 bits (253), Expect = 1e-22
Identities = 42/71 (59%), Positives = 59/71 (83%)
Frame = +2
Query: 41 NPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFIT 220
+PL KYIY+MG+ +RNE LFYR + D++ +MPIVYTPTVGLAC ++G ++RRP+GLFI+
Sbjct: 77 SPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFIS 136
Query: 221 IHDKGHVYDVL 253
I D+GHV ++
Sbjct: 137 ISDRGHVRSIV 147
Score = 101 bits (241), Expect = 3e-21
Identities = 44/58 (75%), Positives = 50/58 (86%)
Frame = +2
Query: 509 LLDEFMRAVVRRYGQNCLVQFEDFGNANAFRLLEKYMNKYCTFNDDIQGTAAVAVAGL 682
L+DEFM+A+ RYG+N L+QFEDFGN NAFR L KY KYCTFNDDIQGTAAVA+AGL
Sbjct: 234 LIDEFMKAITDRYGRNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGL 291
>AF404758-1|AAK95642.1| 569|Homo sapiens NYD-SP12 protein.
Length = 569
Score = 31.1 bits (67), Expect = 3.8
Identities = 19/80 (23%), Positives = 38/80 (47%)
Frame = -1
Query: 277 GRPSPASSKNIVYMSLIVDRDEEAPWSAVHKPELLTGQANRRSVHNWHHFSHVIRDETVE 98
G P A +++I ++ ++ + + KP+L A+R V N +F + +R TV
Sbjct: 213 GEPFDAPAEDIASVASFIETKLVTCYLRMRKPDLALNHAHRSIVLNPAYFRNHLRQATVF 272
Query: 97 QMLIAVQEPHKIDVLVKWIF 38
+ L E + V+ ++F
Sbjct: 273 RCLERYSEAARSAVIADYMF 292
>AF345909-1|AAK29063.2| 569|Homo sapiens NYD-SP12 protein.
Length = 569
Score = 31.1 bits (67), Expect = 3.8
Identities = 19/80 (23%), Positives = 38/80 (47%)
Frame = -1
Query: 277 GRPSPASSKNIVYMSLIVDRDEEAPWSAVHKPELLTGQANRRSVHNWHHFSHVIRDETVE 98
G P A +++I ++ ++ + + KP+L A+R V N +F + +R TV
Sbjct: 213 GEPFDAPAEDIASVASFIETKLVTCYLRMRKPDLALNHAHRSIVLNPAYFRNHLRQATVF 272
Query: 97 QMLIAVQEPHKIDVLVKWIF 38
+ L E + V+ ++F
Sbjct: 273 RCLERYSEAARSAVIADYMF 292
>BC034496-1|AAH34496.1| 569|Homo sapiens spermatogenesis associated
16 protein.
Length = 569
Score = 29.9 bits (64), Expect = 8.8
Identities = 18/80 (22%), Positives = 38/80 (47%)
Frame = -1
Query: 277 GRPSPASSKNIVYMSLIVDRDEEAPWSAVHKPELLTGQANRRSVHNWHHFSHVIRDETVE 98
G P A +++I ++ ++ + + KP+L A+R V N +F + +R TV
Sbjct: 213 GEPFDAPAEDIASVASFIETKLVTCYLRMRKPDLALNHAHRSIVLNPAYFRNHLRQATVF 272
Query: 97 QMLIAVQEPHKIDVLVKWIF 38
+ L E + ++ ++F
Sbjct: 273 RCLERYSEAARSAMIADYMF 292
>AF151875-1|AAD34112.1| 178|Homo sapiens CGI-117 protein protein.
Length = 178
Score = 29.9 bits (64), Expect = 8.8
Identities = 13/40 (32%), Positives = 19/40 (47%)
Frame = +3
Query: 318 GRFRRVRDGHPCGQTRALHRARRHQASSVSTHHYRRGYDH 437
G+ RR + G+ + R ARR A + H R +DH
Sbjct: 6 GKTRRQKFGYSVNRKRLNRNARRKAARGIECSHIRHAWDH 45
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,993,156
Number of Sequences: 237096
Number of extensions: 2335568
Number of successful extensions: 6210
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 5797
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6210
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7727256732
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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