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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= heS00127
         (434 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

U25975-1|AAA75468.1|  493|Homo sapiens hPAK65 protein.                 46   7e-05
U24153-1|AAA65442.1|  525|Homo sapiens p21-activated protein kin...    46   7e-05
BC069613-1|AAH69613.1|  524|Homo sapiens p21-activated kinase 2 ...    46   7e-05
AL357774-2|CAI40843.1|  544|Homo sapiens p21 (CDKN1A)-activated ...    44   3e-04
AL117326-3|CAI43167.1|  544|Homo sapiens p21 (CDKN1A)-activated ...    44   3e-04
AL031117-6|CAI43157.1|  544|Homo sapiens p21 (CDKN1A)-activated ...    44   3e-04
AF068864-1|AAC36097.1|  544|Homo sapiens p21-activated kinase 3 ...    44   3e-04
U51120-1|AAC50590.1|  545|Homo sapiens PAK1 protein.                   43   5e-04
U24152-1|AAA65441.1|  545|Homo sapiens p21-activated protein kin...    43   5e-04
BC109299-1|AAI09300.1|  545|Homo sapiens p21/Cdc42/Rac1-activate...    43   5e-04
AF071884-1|AAC24716.1|  553|Homo sapiens p21 activated kinase 1B...    43   5e-04
AL357774-3|CAI40845.1|  181|Homo sapiens p21 (CDKN1A)-activated ...    38   0.015
AL357774-1|CAI40844.1|  559|Homo sapiens p21 (CDKN1A)-activated ...    38   0.015
AL117326-4|CAI43169.1|  181|Homo sapiens p21 (CDKN1A)-activated ...    38   0.015
AL117326-2|CAI43168.1|  559|Homo sapiens p21 (CDKN1A)-activated ...    38   0.015
AL031117-5|CAI43158.1|  559|Homo sapiens p21 (CDKN1A)-activated ...    38   0.015
AB102659-1|BAC81128.1|  559|Homo sapiens p21-activated kinase 3 ...    38   0.015
AF155651-1|AAF67008.1|  544|Homo sapiens P21-activated kinase 3 ...    35   0.11 
X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine k...    29   5.2  
L36644-1|AAA74245.1|  991|Homo sapiens receptor protein-tyrosine...    29   5.2  
BX537946-1|CAD97914.1|  969|Homo sapiens hypothetical protein pr...    29   5.2  
AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5 i...    29   5.2  
AK127951-1|BAC87203.1|  121|Homo sapiens protein ( Homo sapiens ...    29   6.9  

>U25975-1|AAA75468.1|  493|Homo sapiens hPAK65 protein.
          Length = 493

 Score = 45.6 bits (103), Expect = 7e-05
 Identities = 22/55 (40%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
 Frame = +1

Query: 268 LHVSKNSETGMLEGLPTAWLRLINT-QITAAEQSENPDAAIQAVKFH-MYTIKKK 426
           +HV  ++ TG   G+P  W RL+ T  IT  EQ +NP A +  +KF+   T+K+K
Sbjct: 53  IHVGFDTVTGEFTGMPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSNTVKQK 107


>U24153-1|AAA65442.1|  525|Homo sapiens p21-activated protein kinase
           protein.
          Length = 525

 Score = 45.6 bits (103), Expect = 7e-05
 Identities = 22/55 (40%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
 Frame = +1

Query: 268 LHVSKNSETGMLEGLPTAWLRLINT-QITAAEQSENPDAAIQAVKFH-MYTIKKK 426
           +HV  ++ TG   G+P  W RL+ T  IT  EQ +NP A +  +KF+   T+K+K
Sbjct: 84  IHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSNTVKQK 138


>BC069613-1|AAH69613.1|  524|Homo sapiens p21-activated kinase 2
           protein.
          Length = 524

 Score = 45.6 bits (103), Expect = 7e-05
 Identities = 22/55 (40%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
 Frame = +1

Query: 268 LHVSKNSETGMLEGLPTAWLRLINT-QITAAEQSENPDAAIQAVKFH-MYTIKKK 426
           +HV  ++ TG   G+P  W RL+ T  IT  EQ +NP A +  +KF+   T+K+K
Sbjct: 84  IHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSNTVKQK 138


>AL357774-2|CAI40843.1|  544|Homo sapiens p21 (CDKN1A)-activated
           kinase 3 protein.
          Length = 544

 Score = 43.6 bits (98), Expect = 3e-04
 Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
 Frame = +1

Query: 268 LHVSKNSETGMLEGLPTAWLRLINT-QITAAEQSENPDAAIQAVKFH 405
           +HV  ++ TG   G+P  W RL+ T  IT  EQ +NP A +  +KF+
Sbjct: 80  IHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFY 126


>AL117326-3|CAI43167.1|  544|Homo sapiens p21 (CDKN1A)-activated
           kinase 3 protein.
          Length = 544

 Score = 43.6 bits (98), Expect = 3e-04
 Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
 Frame = +1

Query: 268 LHVSKNSETGMLEGLPTAWLRLINT-QITAAEQSENPDAAIQAVKFH 405
           +HV  ++ TG   G+P  W RL+ T  IT  EQ +NP A +  +KF+
Sbjct: 80  IHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFY 126


>AL031117-6|CAI43157.1|  544|Homo sapiens p21 (CDKN1A)-activated
           kinase 3 protein.
          Length = 544

 Score = 43.6 bits (98), Expect = 3e-04
 Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
 Frame = +1

Query: 268 LHVSKNSETGMLEGLPTAWLRLINT-QITAAEQSENPDAAIQAVKFH 405
           +HV  ++ TG   G+P  W RL+ T  IT  EQ +NP A +  +KF+
Sbjct: 80  IHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFY 126


>AF068864-1|AAC36097.1|  544|Homo sapiens p21-activated kinase 3
           protein.
          Length = 544

 Score = 43.6 bits (98), Expect = 3e-04
 Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
 Frame = +1

Query: 268 LHVSKNSETGMLEGLPTAWLRLINT-QITAAEQSENPDAAIQAVKFH 405
           +HV  ++ TG   G+P  W RL+ T  IT  EQ +NP A +  +KF+
Sbjct: 80  IHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFY 126


>U51120-1|AAC50590.1|  545|Homo sapiens PAK1 protein.
          Length = 545

 Score = 42.7 bits (96), Expect = 5e-04
 Identities = 18/47 (38%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
 Frame = +1

Query: 268 LHVSKNSETGMLEGLPTAWLRLINT-QITAAEQSENPDAAIQAVKFH 405
           +HV  ++ TG   G+P  W RL+ T  IT +EQ +NP A +  ++F+
Sbjct: 85  IHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKNPQAVLDVLEFY 131


>U24152-1|AAA65441.1|  545|Homo sapiens p21-activated protein kinase
           protein.
          Length = 545

 Score = 42.7 bits (96), Expect = 5e-04
 Identities = 18/47 (38%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
 Frame = +1

Query: 268 LHVSKNSETGMLEGLPTAWLRLINT-QITAAEQSENPDAAIQAVKFH 405
           +HV  ++ TG   G+P  W RL+ T  IT +EQ +NP A +  ++F+
Sbjct: 85  IHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKNPQAVLDVLEFY 131


>BC109299-1|AAI09300.1|  545|Homo sapiens p21/Cdc42/Rac1-activated
           kinase 1 (STE20 homolog, yeast) protein.
          Length = 545

 Score = 42.7 bits (96), Expect = 5e-04
 Identities = 18/47 (38%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
 Frame = +1

Query: 268 LHVSKNSETGMLEGLPTAWLRLINT-QITAAEQSENPDAAIQAVKFH 405
           +HV  ++ TG   G+P  W RL+ T  IT +EQ +NP A +  ++F+
Sbjct: 85  IHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKNPQAVLDVLEFY 131


>AF071884-1|AAC24716.1|  553|Homo sapiens p21 activated kinase 1B
           protein.
          Length = 553

 Score = 42.7 bits (96), Expect = 5e-04
 Identities = 18/47 (38%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
 Frame = +1

Query: 268 LHVSKNSETGMLEGLPTAWLRLINT-QITAAEQSENPDAAIQAVKFH 405
           +HV  ++ TG   G+P  W RL+ T  IT +EQ +NP A +  ++F+
Sbjct: 85  IHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKNPQAVLDVLEFY 131


>AL357774-3|CAI40845.1|  181|Homo sapiens p21 (CDKN1A)-activated
           kinase 3 protein.
          Length = 181

 Score = 37.9 bits (84), Expect = 0.015
 Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
 Frame = +1

Query: 304 EGLPTAWLRLINTQ-ITAAEQSENPDAAIQAVKFH 405
           EG+P  W RL+ T  IT  EQ +NP A +  +KF+
Sbjct: 128 EGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFY 162


>AL357774-1|CAI40844.1|  559|Homo sapiens p21 (CDKN1A)-activated
           kinase 3 protein.
          Length = 559

 Score = 37.9 bits (84), Expect = 0.015
 Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
 Frame = +1

Query: 304 EGLPTAWLRLINTQ-ITAAEQSENPDAAIQAVKFH 405
           EG+P  W RL+ T  IT  EQ +NP A +  +KF+
Sbjct: 107 EGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFY 141


>AL117326-4|CAI43169.1|  181|Homo sapiens p21 (CDKN1A)-activated
           kinase 3 protein.
          Length = 181

 Score = 37.9 bits (84), Expect = 0.015
 Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
 Frame = +1

Query: 304 EGLPTAWLRLINTQ-ITAAEQSENPDAAIQAVKFH 405
           EG+P  W RL+ T  IT  EQ +NP A +  +KF+
Sbjct: 128 EGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFY 162


>AL117326-2|CAI43168.1|  559|Homo sapiens p21 (CDKN1A)-activated
           kinase 3 protein.
          Length = 559

 Score = 37.9 bits (84), Expect = 0.015
 Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
 Frame = +1

Query: 304 EGLPTAWLRLINTQ-ITAAEQSENPDAAIQAVKFH 405
           EG+P  W RL+ T  IT  EQ +NP A +  +KF+
Sbjct: 107 EGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFY 141


>AL031117-5|CAI43158.1|  559|Homo sapiens p21 (CDKN1A)-activated
           kinase 3 protein.
          Length = 559

 Score = 37.9 bits (84), Expect = 0.015
 Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
 Frame = +1

Query: 304 EGLPTAWLRLINTQ-ITAAEQSENPDAAIQAVKFH 405
           EG+P  W RL+ T  IT  EQ +NP A +  +KF+
Sbjct: 107 EGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFY 141


>AB102659-1|BAC81128.1|  559|Homo sapiens p21-activated kinase 3
           protein.
          Length = 559

 Score = 37.9 bits (84), Expect = 0.015
 Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
 Frame = +1

Query: 304 EGLPTAWLRLINTQ-ITAAEQSENPDAAIQAVKFH 405
           EG+P  W RL+ T  IT  EQ +NP A +  +KF+
Sbjct: 107 EGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFY 141


>AF155651-1|AAF67008.1|  544|Homo sapiens P21-activated kinase 3
           protein.
          Length = 544

 Score = 35.1 bits (77), Expect = 0.11
 Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
 Frame = +1

Query: 268 LHVSKNSETGMLEGLPTAWLRLINT-QITAAEQSENPDAAIQAVKFH 405
           +HV  ++ TG   G+P  W RL+ T  I   E  E P A  + +KF+
Sbjct: 80  IHVGFDAVTGESLGIPEQWARLLQTSNIPKLEPEEEPQACSRCLKFY 126


>X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine
           kinase protein.
          Length = 1037

 Score = 29.5 bits (63), Expect = 5.2
 Identities = 11/21 (52%), Positives = 13/21 (61%)
 Frame = +1

Query: 127 VCEVTEINQNEWAIGSWCVRE 189
           VC+V E NQN W + SW   E
Sbjct: 101 VCKVMEQNQNNWLLTSWISNE 121


>L36644-1|AAA74245.1|  991|Homo sapiens receptor protein-tyrosine
           kinase protein.
          Length = 991

 Score = 29.5 bits (63), Expect = 5.2
 Identities = 11/21 (52%), Positives = 13/21 (61%)
 Frame = +1

Query: 127 VCEVTEINQNEWAIGSWCVRE 189
           VC+V E NQN W + SW   E
Sbjct: 77  VCKVMEQNQNNWLLTSWISNE 97


>BX537946-1|CAD97914.1|  969|Homo sapiens hypothetical protein
           protein.
          Length = 969

 Score = 29.5 bits (63), Expect = 5.2
 Identities = 11/21 (52%), Positives = 13/21 (61%)
 Frame = +1

Query: 127 VCEVTEINQNEWAIGSWCVRE 189
           VC+V E NQN W + SW   E
Sbjct: 32  VCKVMEQNQNNWLLTSWISNE 52


>AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5
           isoform a variant protein.
          Length = 1017

 Score = 29.5 bits (63), Expect = 5.2
 Identities = 11/21 (52%), Positives = 13/21 (61%)
 Frame = +1

Query: 127 VCEVTEINQNEWAIGSWCVRE 189
           VC+V E NQN W + SW   E
Sbjct: 114 VCKVMEQNQNNWLLTSWISNE 134


>AK127951-1|BAC87203.1|  121|Homo sapiens protein ( Homo sapiens
           cDNA FLJ46062 fis, clone TBAES2005361. ).
          Length = 121

 Score = 29.1 bits (62), Expect = 6.9
 Identities = 12/35 (34%), Positives = 19/35 (54%)
 Frame = -3

Query: 228 LSSRSLCCFLEKSFPNTPRPDRPLILIDFGHFTYD 124
           L+   + C +  S  + P P RPL+L DF   +Y+
Sbjct: 81  LAIPGISCLVAASLQSLPLPSRPLLLGDFSSVSYN 115


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 67,197,479
Number of Sequences: 237096
Number of extensions: 1395542
Number of successful extensions: 2789
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 2719
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2779
length of database: 76,859,062
effective HSP length: 83
effective length of database: 57,180,094
effective search space used: 3487985734
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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