Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= heS00035
(761 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 35 0.28
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 35 0.28
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 35 0.28
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 35 0.28
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 35 0.28
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 35 0.28
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 35 0.28
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 34 0.48
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 34 0.48
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 34 0.48
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 34 0.48
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 34 0.48
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 33 1.5
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 33 1.5
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 33 1.5
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 33 1.5
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 33 1.5
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 32 1.9
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 32 1.9
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 31 5.9
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 31 5.9
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 35.1 bits (77), Expect = 0.28
Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Frame = +2
Query: 569 PSVPPNPVMEVKLGFKLTSF-RYNTLDSKLTTTAAVVVSWEDDSMAWNPDKFNGTTNIKL 745
P + N ++V G K++ + + +TT + W D + WNPD + G +IK+
Sbjct: 46 PVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKV 105
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 35.1 bits (77), Expect = 0.28
Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Frame = +2
Query: 569 PSVPPNPVMEVKLGFKLTSF-RYNTLDSKLTTTAAVVVSWEDDSMAWNPDKFNGTTNIKL 745
P + N ++V G K++ + + +TT + W D + WNPD + G +IK+
Sbjct: 11 PVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKV 70
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 35.1 bits (77), Expect = 0.28
Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Frame = +2
Query: 569 PSVPPNPVMEVKLGFKLTSF-RYNTLDSKLTTTAAVVVSWEDDSMAWNPDKFNGTTNIKL 745
P + N ++V G K++ + + +TT + W D + WNPD + G +IK+
Sbjct: 46 PVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKV 105
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 35.1 bits (77), Expect = 0.28
Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Frame = +2
Query: 569 PSVPPNPVMEVKLGFKLTSF-RYNTLDSKLTTTAAVVVSWEDDSMAWNPDKFNGTTNIKL 745
P + N ++V G K++ + + +TT + W D + WNPD + G +IK+
Sbjct: 46 PVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKV 105
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 35.1 bits (77), Expect = 0.28
Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Frame = +2
Query: 569 PSVPPNPVMEVKLGFKLTSF-RYNTLDSKLTTTAAVVVSWEDDSMAWNPDKFNGTTNIKL 745
P + N ++V G K++ + + +TT + W D + WNPD + G +IK+
Sbjct: 46 PVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKV 105
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 35.1 bits (77), Expect = 0.28
Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Frame = +2
Query: 569 PSVPPNPVMEVKLGFKLTSF-RYNTLDSKLTTTAAVVVSWEDDSMAWNPDKFNGTTNIKL 745
P + N ++V G K++ + + +TT + W D + WNPD + G +IK+
Sbjct: 46 PVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKV 105
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 35.1 bits (77), Expect = 0.28
Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Frame = +2
Query: 569 PSVPPNPVMEVKLGFKLTSF-RYNTLDSKLTTTAAVVVSWEDDSMAWNPDKFNGTTNIKL 745
P + N ++V G K++ + + +TT + W D + WNPD + G +IK+
Sbjct: 46 PVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYGGIHSIKV 105
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 34.3 bits (75), Expect = 0.48
Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Frame = +2
Query: 590 VMEVKLGFKLTSF-RYNTLDSKLTTTAAVVVSWEDDSMAWNPDKFNGTTNIKLRQGQI 760
V+EV +G +L + ++ +TT + W D ++ WNPD + G I + +I
Sbjct: 48 VVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKI 105
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 34.3 bits (75), Expect = 0.48
Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Frame = +2
Query: 590 VMEVKLGFKLTSF-RYNTLDSKLTTTAAVVVSWEDDSMAWNPDKFNGTTNIKLRQGQI 760
V+EV +G +L + ++ +TT + W D ++ WNPD + G I + +I
Sbjct: 48 VVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKI 105
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 34.3 bits (75), Expect = 0.48
Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Frame = +2
Query: 590 VMEVKLGFKLTSF-RYNTLDSKLTTTAAVVVSWEDDSMAWNPDKFNGTTNIKLRQGQI 760
V+EV +G +L + ++ +TT + W D ++ WNPD + G I + +I
Sbjct: 48 VVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKI 105
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 34.3 bits (75), Expect = 0.48
Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Frame = +2
Query: 590 VMEVKLGFKLTSF-RYNTLDSKLTTTAAVVVSWEDDSMAWNPDKFNGTTNIKLRQGQI 760
V+EV +G +L + ++ +TT + W D ++ WNPD + G I + +I
Sbjct: 48 VVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKI 105
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 34.3 bits (75), Expect = 0.48
Identities = 16/58 (27%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Frame = +2
Query: 590 VMEVKLGFKLTSF-RYNTLDSKLTTTAAVVVSWEDDSMAWNPDKFNGTTNIKLRQGQI 760
V+EV +G +L + ++ +TT + W D ++ WNPD + G I + +I
Sbjct: 48 VVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKI 105
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/53 (30%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Frame = +2
Query: 611 FKLTSFRYNTLDSK---LTTTAAVVVSWEDDSMAWNPDKFNGTTNIKLRQGQI 760
F L+ + +D K LTT + +SW D + WN ++ G ++ GQI
Sbjct: 32 FSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQI 84
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/53 (30%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Frame = +2
Query: 611 FKLTSFRYNTLDSK---LTTTAAVVVSWEDDSMAWNPDKFNGTTNIKLRQGQI 760
F L+ + +D K LTT + +SW D + WN ++ G ++ GQI
Sbjct: 55 FSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQI 107
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/53 (30%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Frame = +2
Query: 611 FKLTSFRYNTLDSK---LTTTAAVVVSWEDDSMAWNPDKFNGTTNIKLRQGQI 760
F L+ + +D K LTT + +SW D + WN ++ G ++ GQI
Sbjct: 55 FSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQI 107
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/53 (30%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Frame = +2
Query: 611 FKLTSFRYNTLDSK---LTTTAAVVVSWEDDSMAWNPDKFNGTTNIKLRQGQI 760
F L+ + +D K LTT + +SW D + WN ++ G ++ GQI
Sbjct: 55 FSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQI 107
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/53 (30%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Frame = +2
Query: 611 FKLTSFRYNTLDSK---LTTTAAVVVSWEDDSMAWNPDKFNGTTNIKLRQGQI 760
F L+ + +D K LTT + +SW D + WN ++ G ++ GQI
Sbjct: 55 FSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQI 107
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 32.3 bits (70), Expect = 1.9
Identities = 16/53 (30%), Positives = 25/53 (47%), Gaps = 3/53 (5%)
Frame = +2
Query: 611 FKLTSFRYNTLDSK---LTTTAAVVVSWEDDSMAWNPDKFNGTTNIKLRQGQI 760
F L + +D K LTT + +SW D + WN ++ G ++ GQI
Sbjct: 55 FSLNLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQI 107
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 32.3 bits (70), Expect = 1.9
Identities = 16/53 (30%), Positives = 25/53 (47%), Gaps = 3/53 (5%)
Frame = +2
Query: 611 FKLTSFRYNTLDSK---LTTTAAVVVSWEDDSMAWNPDKFNGTTNIKLRQGQI 760
F L + +D K LTT + +SW D + WN ++ G ++ GQI
Sbjct: 55 FSLNLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQI 107
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 30.7 bits (66), Expect = 5.9
Identities = 15/63 (23%), Positives = 29/63 (46%), Gaps = 1/63 (1%)
Frame = +2
Query: 560 GRLPSVPPNPVMEVKLGFKLTSF-RYNTLDSKLTTTAAVVVSWEDDSMAWNPDKFNGTTN 736
G P P + + L LT+ N + LTT+ + + W+D + ++ D F G
Sbjct: 38 GSRPVREPEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIET 97
Query: 737 IKL 745
+++
Sbjct: 98 LRV 100
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 30.7 bits (66), Expect = 5.9
Identities = 15/63 (23%), Positives = 29/63 (46%), Gaps = 1/63 (1%)
Frame = +2
Query: 560 GRLPSVPPNPVMEVKLGFKLTSF-RYNTLDSKLTTTAAVVVSWEDDSMAWNPDKFNGTTN 736
G P P + + L LT+ N + LTT+ + + W+D + ++ D F G
Sbjct: 38 GSRPVREPEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIET 97
Query: 737 IKL 745
+++
Sbjct: 98 LRV 100
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 116,832,151
Number of Sequences: 237096
Number of extensions: 2571859
Number of successful extensions: 5363
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 5126
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5363
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9144232952
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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