Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= heS00027
(706 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens ... 79 2e-14
AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein. 79 2e-14
AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1 pro... 79 2e-14
AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein. 79 2e-14
BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein. 77 5e-14
X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein. 75 2e-13
BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis, ... 75 2e-13
AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis, ... 75 2e-13
AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis, ... 75 3e-13
AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis, ... 75 3e-13
AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis, ... 75 3e-13
M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protei... 62 1e-09
BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin ... 62 1e-09
BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin ... 62 1e-09
AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein. 62 1e-09
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 56 1e-07
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 56 1e-07
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 56 1e-07
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 56 1e-07
X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for ... 53 1e-06
U12026-1|AAA92670.1| 172|Homo sapiens Cap-G protein. 53 1e-06
BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein. 53 1e-06
BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein. 53 1e-06
AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein. 53 1e-06
AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein. 53 1e-06
AL160060-2|CAH71300.1| 2214|Homo sapiens supervillin protein. 51 4e-06
AL160060-1|CAH71301.1| 1788|Homo sapiens supervillin protein. 51 4e-06
AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein. 51 4e-06
AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein. 51 4e-06
AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein. 51 4e-06
AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein. 51 4e-06
AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein. 51 4e-06
X07066-1|CAA30102.1| 69|Homo sapiens protein ( Human gene for ... 40 0.009
BC075797-1|AAH75797.1| 85|Homo sapiens Unknown (protein for MG... 38 0.026
AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis, ... 34 0.43
AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens ... 33 0.99
AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens ... 33 0.99
BX537759-1|CAD97828.1| 1763|Homo sapiens hypothetical protein pr... 31 5.3
BC146782-1|AAI46783.1| 1814|Homo sapiens CDK5 regulatory subunit... 31 5.3
BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin (am... 31 5.3
AL353736-4|CAI40656.1| 400|Homo sapiens CDK5 regulatory subunit... 31 5.3
AK025867-1|BAB15263.1| 350|Homo sapiens protein ( Homo sapiens ... 31 5.3
AB046853-1|BAB13459.2| 1852|Homo sapiens KIAA1633 protein protein. 31 5.3
D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein. 30 7.0
BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein. 30 7.0
BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein. 30 7.0
AB209582-1|BAD92819.1| 272|Homo sapiens regulator of G-protein ... 30 9.3
>AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens
cDNA FLJ90642 fis, clone PLACE1004078, highly similar to
Bovine mRNA for adseverin. ).
Length = 715
Score = 78.6 bits (185), Expect = 2e-14
Identities = 59/188 (31%), Positives = 81/188 (43%), Gaps = 5/188 (2%)
Frame = +3
Query: 156 HPAFANVGRTAGVQIWRIQNFEPIPVAQKD-----IGKSTKEIHTSFYGRPRTVATIYHG 320
H FA G+ AG+Q+WRI+ E +PV Q +G + +HT+ R T YH
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLMLHTAKTSRGFT----YHL 62
Query: 321 ISTTGSVGSRRKTSQEPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGR 500
G S+ + S F + G G F L G
Sbjct: 63 HFWLGKECSQDE-STAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGG 121
Query: 501 ESVGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEK 680
+ G NHV+TN KR+ VKG+R VR +V S NKGDCF++ L +IY + G
Sbjct: 122 VASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSS 181
Query: 681 AKNVEKLK 704
E+LK
Sbjct: 182 CNKYERLK 189
Score = 51.6 bits (118), Expect = 3e-06
Identities = 22/48 (45%), Positives = 33/48 (68%)
Frame = +2
Query: 245 HRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTL 388
H Y GD+Y++L T SR ++ +H+W+G+E +QDES AAAI T+
Sbjct: 37 HGDFYVGDAYLMLHTAKTSRG-FTYHLHFWLGKECSQDESTAAAIFTV 83
Score = 44.8 bits (101), Expect = 3e-04
Identities = 23/46 (50%), Positives = 28/46 (60%)
Frame = +1
Query: 379 FNVGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGGNPSVL 516
F V +DD GG VQ+RE G+ES F+SYF+ L Y GG S L
Sbjct: 81 FTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGL 126
Score = 33.1 bits (72), Expect = 0.99
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 8/81 (9%)
Frame = +3
Query: 480 LDLFGGRESVGFNHVVTNAGAQK-----RMFQVKGKRD--VRVRQVDPQIASMNKGDCFV 638
L LF + + + + + G Q R+FQV+ R+ +VD S+N D FV
Sbjct: 483 LSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFV 542
Query: 639 LSL-DNDIYVFVGEKAKNVEK 698
L L N Y++VG+ A E+
Sbjct: 543 LKLPQNSGYIWVGKGASQEEE 563
>AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein.
Length = 715
Score = 78.6 bits (185), Expect = 2e-14
Identities = 59/188 (31%), Positives = 81/188 (43%), Gaps = 5/188 (2%)
Frame = +3
Query: 156 HPAFANVGRTAGVQIWRIQNFEPIPVAQKD-----IGKSTKEIHTSFYGRPRTVATIYHG 320
H FA G+ AG+Q+WRI+ E +PV Q +G + +HT+ R T YH
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFT----YHL 62
Query: 321 ISTTGSVGSRRKTSQEPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGR 500
G S+ + S F + G G F L G
Sbjct: 63 HFWLGKECSQDE-STAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGG 121
Query: 501 ESVGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEK 680
+ G NHV+TN KR+ VKG+R VR +V S NKGDCF++ L +IY + G
Sbjct: 122 VASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSS 181
Query: 681 AKNVEKLK 704
E+LK
Sbjct: 182 CNKYERLK 189
Score = 52.4 bits (120), Expect = 2e-06
Identities = 22/48 (45%), Positives = 33/48 (68%)
Frame = +2
Query: 245 HRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTL 388
H Y GD+Y++L T SR ++ +H+W+G+E +QDES AAAI T+
Sbjct: 37 HGDFYVGDAYLVLHTAKTSRG-FTYHLHFWLGKECSQDESTAAAIFTV 83
Score = 44.8 bits (101), Expect = 3e-04
Identities = 23/46 (50%), Positives = 28/46 (60%)
Frame = +1
Query: 379 FNVGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGGNPSVL 516
F V +DD GG VQ+RE G+ES F+SYF+ L Y GG S L
Sbjct: 81 FTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGL 126
Score = 33.1 bits (72), Expect = 0.99
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 8/81 (9%)
Frame = +3
Query: 480 LDLFGGRESVGFNHVVTNAGAQK-----RMFQVKGKRD--VRVRQVDPQIASMNKGDCFV 638
L LF + + + + + G Q R+FQV+ R+ +VD S+N D FV
Sbjct: 483 LSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFV 542
Query: 639 LSL-DNDIYVFVGEKAKNVEK 698
L L N Y++VG+ A E+
Sbjct: 543 LKLSQNSGYIWVGKGASQEEE 563
>AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1
protein.
Length = 527
Score = 78.6 bits (185), Expect = 2e-14
Identities = 59/188 (31%), Positives = 81/188 (43%), Gaps = 5/188 (2%)
Frame = +3
Query: 156 HPAFANVGRTAGVQIWRIQNFEPIPVAQKD-----IGKSTKEIHTSFYGRPRTVATIYHG 320
H FA G+ AG+Q+WRI+ E +PV Q +G + +HT+ R T YH
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFT----YHL 62
Query: 321 ISTTGSVGSRRKTSQEPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGR 500
G S+ + S F + G G F L G
Sbjct: 63 HFWLGKECSQDE-STAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGG 121
Query: 501 ESVGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEK 680
+ G NHV+TN KR+ VKG+R VR +V S NKGDCF++ L +IY + G
Sbjct: 122 VASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSS 181
Query: 681 AKNVEKLK 704
E+LK
Sbjct: 182 CNKYERLK 189
Score = 52.4 bits (120), Expect = 2e-06
Identities = 22/48 (45%), Positives = 33/48 (68%)
Frame = +2
Query: 245 HRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTL 388
H Y GD+Y++L T SR ++ +H+W+G+E +QDES AAAI T+
Sbjct: 37 HGDFYVGDAYLVLHTAKTSRG-FTYHLHFWLGKECSQDESTAAAIFTV 83
Score = 44.8 bits (101), Expect = 3e-04
Identities = 23/46 (50%), Positives = 28/46 (60%)
Frame = +1
Query: 379 FNVGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGGNPSVL 516
F V +DD GG VQ+RE G+ES F+SYF+ L Y GG S L
Sbjct: 81 FTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGL 126
>AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein.
Length = 626
Score = 78.6 bits (185), Expect = 2e-14
Identities = 59/188 (31%), Positives = 81/188 (43%), Gaps = 5/188 (2%)
Frame = +3
Query: 156 HPAFANVGRTAGVQIWRIQNFEPIPVAQKD-----IGKSTKEIHTSFYGRPRTVATIYHG 320
H FA G+ AG+Q+WRI+ E +PV Q +G + +HT+ R T YH
Sbjct: 53 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFT----YHL 108
Query: 321 ISTTGSVGSRRKTSQEPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGR 500
G S+ + S F + G G F L G
Sbjct: 109 HFWLGKECSQDE-STAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGG 167
Query: 501 ESVGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEK 680
+ G NHV+TN KR+ VKG+R VR +V S NKGDCF++ L +IY + G
Sbjct: 168 VASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSS 227
Query: 681 AKNVEKLK 704
E+LK
Sbjct: 228 CNKYERLK 235
Score = 52.4 bits (120), Expect = 2e-06
Identities = 22/48 (45%), Positives = 33/48 (68%)
Frame = +2
Query: 245 HRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTL 388
H Y GD+Y++L T SR ++ +H+W+G+E +QDES AAAI T+
Sbjct: 83 HGDFYVGDAYLVLHTAKTSRG-FTYHLHFWLGKECSQDESTAAAIFTV 129
Score = 44.8 bits (101), Expect = 3e-04
Identities = 23/46 (50%), Positives = 28/46 (60%)
Frame = +1
Query: 379 FNVGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGGNPSVL 516
F V +DD GG VQ+RE G+ES F+SYF+ L Y GG S L
Sbjct: 127 FTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGL 172
>BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein.
Length = 715
Score = 77.4 bits (182), Expect = 5e-14
Identities = 59/191 (30%), Positives = 83/191 (43%), Gaps = 8/191 (4%)
Frame = +3
Query: 156 HPAFANVGRTAGVQIWRIQNFEPIPVAQKD-----IGKSTKEIHTSFYGRPRTVATIYHG 320
H FA G+ AG+Q+WRI+ E +PV Q +G + +HT+ R T ++
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYR-LHFW 65
Query: 321 ISTTGSVGSRRKTSQEPPQFQRWPGR---QVRGHSGPAPRDHGSRKCFVPIIFPDTLDLF 491
+ S + Q + G Q R G D S F L
Sbjct: 66 LGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVS-------YFKGGLKYK 118
Query: 492 GGRESVGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFV 671
G + G NHV+TN KR+ VKG+R VR +V S NKGDCF++ L +IY +
Sbjct: 119 AGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWC 178
Query: 672 GEKAKNVEKLK 704
G E+LK
Sbjct: 179 GSSCNKYERLK 189
Score = 52.0 bits (119), Expect = 2e-06
Identities = 22/48 (45%), Positives = 33/48 (68%)
Frame = +2
Query: 245 HRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTL 388
H Y GD+Y++L T SR ++ +H+W+G+E +QDES AAAI T+
Sbjct: 37 HGDFYVGDAYLVLHTAKTSRG-FTYRLHFWLGKECSQDESTAAAIFTV 83
Score = 44.8 bits (101), Expect = 3e-04
Identities = 23/46 (50%), Positives = 28/46 (60%)
Frame = +1
Query: 379 FNVGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGGNPSVL 516
F V +DD GG VQ+RE G+ES F+SYF+ L Y GG S L
Sbjct: 81 FTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGL 126
Score = 33.1 bits (72), Expect = 0.99
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 8/81 (9%)
Frame = +3
Query: 480 LDLFGGRESVGFNHVVTNAGAQK-----RMFQVKGKRD--VRVRQVDPQIASMNKGDCFV 638
L LF + + + + + G Q R+FQV+ R+ +VD S+N D FV
Sbjct: 483 LSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFV 542
Query: 639 LSL-DNDIYVFVGEKAKNVEK 698
L L N Y++VG+ A E+
Sbjct: 543 LKLPQNSGYIWVGKGASQEEE 563
>X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein.
Length = 782
Score = 75.4 bits (177), Expect = 2e-13
Identities = 57/215 (26%), Positives = 87/215 (40%), Gaps = 2/215 (0%)
Frame = +3
Query: 66 VWARTATKPQEISG-PITSLSDKNARDKAKVHPAFANVGRTAGVQIWRIQNFEPIPVAQK 242
V A TA++ +G P + + HP F G+ G+QIWR++ F+ +PV
Sbjct: 25 VRAATASRGASQAGAPQGRVPEARPNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTN 84
Query: 243 DIGKS-TKEIHTSFYGRPRTVATIYHGISTTGSVGSRRKTSQEPPQFQRWPGRQVRGHSG 419
G T + + + + + + S F + G +
Sbjct: 85 LYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAV 144
Query: 420 PAPRDHGSRKCFVPIIFPDTLDLFGGRESVGFNHVVTNAGAQKRMFQVKGKRDVRVRQVD 599
G F L G + GF HVV N +R+FQVKG+R VR +V
Sbjct: 145 QHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVP 204
Query: 600 PQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLK 704
S N GDCF+L L N+I+ + G + E+LK
Sbjct: 205 VSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLK 239
Score = 60.5 bits (140), Expect = 6e-09
Identities = 24/44 (54%), Positives = 33/44 (75%)
Frame = +2
Query: 257 YKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTL 388
+ GD+Y+IL+T NL +D+HYW+G E +QDESGAAAI T+
Sbjct: 90 FTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTV 133
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/41 (58%), Positives = 27/41 (65%)
Frame = +1
Query: 379 FNVGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGG 501
F V LDD G AVQHRE G ESA FL YF++ L Y +GG
Sbjct: 131 FTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 171
Score = 34.3 bits (75), Expect = 0.43
Identities = 20/45 (44%), Positives = 24/45 (53%)
Frame = +2
Query: 251 KIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAIST 385
+ Y GDSYIIL I+ W G +STQDE A+AI T
Sbjct: 467 QFYGGDSYIILYNYRHGGRQ-GQIIYNWQGAQSTQDEVAASAILT 510
Score = 30.7 bits (66), Expect = 5.3
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Frame = +1
Query: 391 LDDKFGGTAVQHRETMGHESALFLSYF-QTPLTYLEGG 501
LD++ GGT VQ R G E A +S F P+ +GG
Sbjct: 513 LDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGG 550
>BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 782
Score = 75.4 bits (177), Expect = 2e-13
Identities = 57/215 (26%), Positives = 87/215 (40%), Gaps = 2/215 (0%)
Frame = +3
Query: 66 VWARTATKPQEISG-PITSLSDKNARDKAKVHPAFANVGRTAGVQIWRIQNFEPIPVAQK 242
V A TA++ +G P + + HP F G+ G+QIWR++ F+ +PV
Sbjct: 25 VRAATASRGASQAGAPQGRVPEARPNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTN 84
Query: 243 DIGKS-TKEIHTSFYGRPRTVATIYHGISTTGSVGSRRKTSQEPPQFQRWPGRQVRGHSG 419
G T + + + + + + S F + G +
Sbjct: 85 LYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAV 144
Query: 420 PAPRDHGSRKCFVPIIFPDTLDLFGGRESVGFNHVVTNAGAQKRMFQVKGKRDVRVRQVD 599
G F L G + GF HVV N +R+FQVKG+R VR +V
Sbjct: 145 QHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVP 204
Query: 600 PQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLK 704
S N GDCF+L L N+I+ + G + E+LK
Sbjct: 205 VSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLK 239
Score = 60.5 bits (140), Expect = 6e-09
Identities = 24/44 (54%), Positives = 33/44 (75%)
Frame = +2
Query: 257 YKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTL 388
+ GD+Y+IL+T NL +D+HYW+G E +QDESGAAAI T+
Sbjct: 90 FTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTV 133
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/41 (58%), Positives = 27/41 (65%)
Frame = +1
Query: 379 FNVGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGG 501
F V LDD G AVQHRE G ESA FL YF++ L Y +GG
Sbjct: 131 FTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 171
Score = 34.3 bits (75), Expect = 0.43
Identities = 20/45 (44%), Positives = 24/45 (53%)
Frame = +2
Query: 251 KIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAIST 385
+ Y GDSYIIL I+ W G +STQDE A+AI T
Sbjct: 467 QFYGGDSYIILYNYRHGGRQ-GQIIYNWQGAQSTQDEVAASAILT 510
Score = 30.7 bits (66), Expect = 5.3
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Frame = +1
Query: 391 LDDKFGGTAVQHRETMGHESALFLSYF-QTPLTYLEGG 501
LD++ GGT VQ R G E A +S F P+ +GG
Sbjct: 513 LDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGG 550
>AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 782
Score = 75.4 bits (177), Expect = 2e-13
Identities = 57/215 (26%), Positives = 87/215 (40%), Gaps = 2/215 (0%)
Frame = +3
Query: 66 VWARTATKPQEISG-PITSLSDKNARDKAKVHPAFANVGRTAGVQIWRIQNFEPIPVAQK 242
V A TA++ +G P + + HP F G+ G+QIWR++ F+ +PV
Sbjct: 25 VRAATASRGASQAGAPQGRVPEARPNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTN 84
Query: 243 DIGKS-TKEIHTSFYGRPRTVATIYHGISTTGSVGSRRKTSQEPPQFQRWPGRQVRGHSG 419
G T + + + + + + S F + G +
Sbjct: 85 LYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAV 144
Query: 420 PAPRDHGSRKCFVPIIFPDTLDLFGGRESVGFNHVVTNAGAQKRMFQVKGKRDVRVRQVD 599
G F L G + GF HVV N +R+FQVKG+R VR +V
Sbjct: 145 QHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVP 204
Query: 600 PQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLK 704
S N GDCF+L L N+I+ + G + E+LK
Sbjct: 205 VSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLK 239
Score = 60.5 bits (140), Expect = 6e-09
Identities = 24/44 (54%), Positives = 33/44 (75%)
Frame = +2
Query: 257 YKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTL 388
+ GD+Y+IL+T NL +D+HYW+G E +QDESGAAAI T+
Sbjct: 90 FTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTV 133
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/41 (58%), Positives = 27/41 (65%)
Frame = +1
Query: 379 FNVGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGG 501
F V LDD G AVQHRE G ESA FL YF++ L Y +GG
Sbjct: 131 FTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 171
Score = 34.3 bits (75), Expect = 0.43
Identities = 20/45 (44%), Positives = 24/45 (53%)
Frame = +2
Query: 251 KIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAIST 385
+ Y GDSYIIL I+ W G +STQDE A+AI T
Sbjct: 467 QFYGGDSYIILYNYRHGGRQ-GQIIYNWQGAQSTQDEVAASAILT 510
Score = 30.7 bits (66), Expect = 5.3
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Frame = +1
Query: 391 LDDKFGGTAVQHRETMGHESALFLSYF-QTPLTYLEGG 501
LD++ GGT VQ R G E A +S F P+ +GG
Sbjct: 513 LDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGG 550
>AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 731
Score = 74.5 bits (175), Expect = 3e-13
Identities = 51/184 (27%), Positives = 76/184 (41%), Gaps = 1/184 (0%)
Frame = +3
Query: 156 HPAFANVGRTAGVQIWRIQNFEPIPVAQKDIGKS-TKEIHTSFYGRPRTVATIYHGISTT 332
HP F G+ G+QIWR++ F+ +PV G T + + + + +
Sbjct: 5 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64
Query: 333 GSVGSRRKTSQEPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGRESVG 512
+ S F + G + G F L G + G
Sbjct: 65 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 124
Query: 513 FNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNV 692
F HVV N +R+FQVKG+R VR +V S N GDCF+L L N+I+ + G +
Sbjct: 125 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 184
Query: 693 EKLK 704
E+LK
Sbjct: 185 ERLK 188
Score = 60.5 bits (140), Expect = 6e-09
Identities = 24/44 (54%), Positives = 33/44 (75%)
Frame = +2
Query: 257 YKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTL 388
+ GD+Y+IL+T NL +D+HYW+G E +QDESGAAAI T+
Sbjct: 39 FTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTV 82
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/41 (58%), Positives = 27/41 (65%)
Frame = +1
Query: 379 FNVGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGG 501
F V LDD G AVQHRE G ESA FL YF++ L Y +GG
Sbjct: 80 FTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 120
Score = 34.3 bits (75), Expect = 0.43
Identities = 20/45 (44%), Positives = 24/45 (53%)
Frame = +2
Query: 251 KIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAIST 385
+ Y GDSYIIL I+ W G +STQDE A+AI T
Sbjct: 416 QFYGGDSYIILYNYRHGGRQ-GQIIYNWQGAQSTQDEVAASAILT 459
Score = 30.7 bits (66), Expect = 5.3
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Frame = +1
Query: 391 LDDKFGGTAVQHRETMGHESALFLSYF-QTPLTYLEGG 501
LD++ GGT VQ R G E A +S F P+ +GG
Sbjct: 462 LDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGG 499
>AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 260
Score = 74.5 bits (175), Expect = 3e-13
Identities = 51/184 (27%), Positives = 76/184 (41%), Gaps = 1/184 (0%)
Frame = +3
Query: 156 HPAFANVGRTAGVQIWRIQNFEPIPVAQKDIGKS-TKEIHTSFYGRPRTVATIYHGISTT 332
HP F G+ G+QIWR++ F+ +PV G T + + + + +
Sbjct: 5 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 64
Query: 333 GSVGSRRKTSQEPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGRESVG 512
+ S F + G + G F L G + G
Sbjct: 65 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 124
Query: 513 FNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNV 692
F HVV N +R+FQVKG+R VR +V S N GDCF+L L N+I+ + G +
Sbjct: 125 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 184
Query: 693 EKLK 704
E+LK
Sbjct: 185 ERLK 188
Score = 60.5 bits (140), Expect = 6e-09
Identities = 24/44 (54%), Positives = 33/44 (75%)
Frame = +2
Query: 257 YKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTL 388
+ GD+Y+IL+T NL +D+HYW+G E +QDESGAAAI T+
Sbjct: 39 FTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTV 82
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/41 (58%), Positives = 27/41 (65%)
Frame = +1
Query: 379 FNVGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGG 501
F V LDD G AVQHRE G ESA FL YF++ L Y +GG
Sbjct: 80 FTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 120
>AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 228
Score = 74.5 bits (175), Expect = 3e-13
Identities = 51/184 (27%), Positives = 76/184 (41%), Gaps = 1/184 (0%)
Frame = +3
Query: 156 HPAFANVGRTAGVQIWRIQNFEPIPVAQKDIGKS-TKEIHTSFYGRPRTVATIYHGISTT 332
HP F G+ G+QIWR++ F+ +PV G T + + + + +
Sbjct: 16 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 75
Query: 333 GSVGSRRKTSQEPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGRESVG 512
+ S F + G + G F L G + G
Sbjct: 76 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 135
Query: 513 FNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNV 692
F HVV N +R+FQVKG+R VR +V S N GDCF+L L N+I+ + G +
Sbjct: 136 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 195
Query: 693 EKLK 704
E+LK
Sbjct: 196 ERLK 199
Score = 60.5 bits (140), Expect = 6e-09
Identities = 24/44 (54%), Positives = 33/44 (75%)
Frame = +2
Query: 257 YKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTL 388
+ GD+Y+IL+T NL +D+HYW+G E +QDESGAAAI T+
Sbjct: 50 FTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTV 93
Score = 52.0 bits (119), Expect = 2e-06
Identities = 24/41 (58%), Positives = 27/41 (65%)
Frame = +1
Query: 379 FNVGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGG 501
F V LDD G AVQHRE G ESA FL YF++ L Y +GG
Sbjct: 91 FTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 131
>M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protein
protein.
Length = 348
Score = 62.5 bits (145), Expect = 1e-09
Identities = 44/174 (25%), Positives = 78/174 (44%), Gaps = 2/174 (1%)
Frame = +3
Query: 189 GVQIWRIQNFEPIPVAQKDIGKS-TKEIHTSFYGRPRTVATIYHGISTTGSVGSRRKTSQ 365
G+ +WR++ +P+PVAQ++ G + + + + P V+ ++ I S + +
Sbjct: 20 GLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHLHLWIGQQSSRDEQGACAV 79
Query: 366 EPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGRESVGFNHVVTNAGAQ 545
G + H G+ FP L G F+ T A A
Sbjct: 80 LAVHLNTLLGERPVQHR----EVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTGAPAA 135
Query: 546 -KRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLK 704
K+++QVKGK+++R + S N GDCF+L L +I+ + G K+ +E+ K
Sbjct: 136 IKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNK 189
Score = 44.0 bits (99), Expect = 5e-04
Identities = 23/48 (47%), Positives = 27/48 (56%)
Frame = +1
Query: 385 VGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGGNPSVLTTSS 528
V L+ G VQHRE G+ES LF+SYF L Y EGG S +S
Sbjct: 82 VHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTS 129
Score = 39.5 bits (88), Expect = 0.011
Identities = 19/57 (33%), Positives = 31/57 (54%)
Frame = +2
Query: 239 EGHRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTLAWTTSSG 409
E + GDSY++L + ++L H WIG++S++DE GA A+ + T G
Sbjct: 37 ENQGVFFSGDSYLVLHNGPEEVSHL----HLWIGQQSSRDEQGACAVLAVHLNTLLG 89
>BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin
filament), gelsolin-like protein.
Length = 348
Score = 62.5 bits (145), Expect = 1e-09
Identities = 44/174 (25%), Positives = 78/174 (44%), Gaps = 2/174 (1%)
Frame = +3
Query: 189 GVQIWRIQNFEPIPVAQKDIGKS-TKEIHTSFYGRPRTVATIYHGISTTGSVGSRRKTSQ 365
G+ +WR++ +P+PVAQ++ G + + + + P V+ ++ I S + +
Sbjct: 20 GLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHLHLWIGQQSSRDEQGACAV 79
Query: 366 EPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGRESVGFNHVVTNAGAQ 545
G + H G+ FP L G F+ T A A
Sbjct: 80 LAVHLNTLLGERPVQHR----EVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTGAPAA 135
Query: 546 -KRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLK 704
K+++QVKGK+++R + S N GDCF+L L +I+ + G K+ +E+ K
Sbjct: 136 IKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNK 189
Score = 44.0 bits (99), Expect = 5e-04
Identities = 23/48 (47%), Positives = 27/48 (56%)
Frame = +1
Query: 385 VGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGGNPSVLTTSS 528
V L+ G VQHRE G+ES LF+SYF L Y EGG S +S
Sbjct: 82 VHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTS 129
Score = 39.5 bits (88), Expect = 0.011
Identities = 19/57 (33%), Positives = 31/57 (54%)
Frame = +2
Query: 239 EGHRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTLAWTTSSG 409
E + GDSY++L + ++L H WIG++S++DE GA A+ + T G
Sbjct: 37 ENQGVFFSGDSYLVLHNGPEEVSHL----HLWIGQQSSRDEQGACAVLAVHLNTLLG 89
>BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin
filament), gelsolin-like protein.
Length = 348
Score = 62.5 bits (145), Expect = 1e-09
Identities = 44/174 (25%), Positives = 78/174 (44%), Gaps = 2/174 (1%)
Frame = +3
Query: 189 GVQIWRIQNFEPIPVAQKDIGKS-TKEIHTSFYGRPRTVATIYHGISTTGSVGSRRKTSQ 365
G+ +WR++ +P+PVAQ++ G + + + + P V+ ++ I S + +
Sbjct: 20 GLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHLHLWIGQQSSRDEQGACAV 79
Query: 366 EPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGRESVGFNHVVTNAGAQ 545
G + H G+ FP L G F+ T A A
Sbjct: 80 LAVHLNTLLGERPVQHR----EVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTGAPAA 135
Query: 546 -KRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLK 704
K+++QVKGK+++R + S N GDCF+L L +I+ + G K+ +E+ K
Sbjct: 136 IKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNK 189
Score = 44.0 bits (99), Expect = 5e-04
Identities = 23/48 (47%), Positives = 27/48 (56%)
Frame = +1
Query: 385 VGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGGNPSVLTTSS 528
V L+ G VQHRE G+ES LF+SYF L Y EGG S +S
Sbjct: 82 VHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTS 129
Score = 39.5 bits (88), Expect = 0.011
Identities = 19/57 (33%), Positives = 31/57 (54%)
Frame = +2
Query: 239 EGHRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTLAWTTSSG 409
E + GDSY++L + ++L H WIG++S++DE GA A+ + T G
Sbjct: 37 ENQGVFFSGDSYLVLHNGPEEVSHL----HLWIGQQSSRDEQGACAVLAVHLNTLLG 89
>AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein.
Length = 348
Score = 62.5 bits (145), Expect = 1e-09
Identities = 44/174 (25%), Positives = 78/174 (44%), Gaps = 2/174 (1%)
Frame = +3
Query: 189 GVQIWRIQNFEPIPVAQKDIGKS-TKEIHTSFYGRPRTVATIYHGISTTGSVGSRRKTSQ 365
G+ +WR++ +P+PVAQ++ G + + + + P V+ ++ I S + +
Sbjct: 20 GLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHLHLWIGQQSSRDEQGACAV 79
Query: 366 EPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGRESVGFNHVVTNAGAQ 545
G + H G+ FP L G F+ T A A
Sbjct: 80 LAVHLNTLLGERPVQHR----EVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTGAPAA 135
Query: 546 -KRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLK 704
K+++QVKGK+++R + S N GDCF+L L +I+ + G K+ +E+ K
Sbjct: 136 IKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNK 189
Score = 44.0 bits (99), Expect = 5e-04
Identities = 23/48 (47%), Positives = 27/48 (56%)
Frame = +1
Query: 385 VGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGGNPSVLTTSS 528
V L+ G VQHRE G+ES LF+SYF L Y EGG S +S
Sbjct: 82 VHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTS 129
Score = 39.5 bits (88), Expect = 0.011
Identities = 19/57 (33%), Positives = 31/57 (54%)
Frame = +2
Query: 239 EGHRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTLAWTTSSG 409
E + GDSY++L + ++L H WIG++S++DE GA A+ + T G
Sbjct: 37 ENQGVFFSGDSYLVLHNGPEEVSHL----HLWIGQQSSRDEQGACAVLAVHLNTLLG 89
>U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein.
Length = 1269
Score = 56.0 bits (129), Expect = 1e-07
Identities = 23/57 (40%), Positives = 35/57 (61%)
Frame = +2
Query: 245 HRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTLAWTTSSGAQ 415
H K Y+ D YI+L+T D +L+W+I+YWIG E+T D+ +AI + GA+
Sbjct: 519 HGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAE 575
Score = 42.3 bits (95), Expect = 0.002
Identities = 39/176 (22%), Positives = 80/176 (45%), Gaps = 5/176 (2%)
Frame = +3
Query: 171 NVGRTAGVQIWRIQNFEPIPVAQKDIGKSTKE----IHTSFYGRPRTVA-TIYHGISTTG 335
+VG+ G+ IW+I+NF P+ V + GK + + +F ++ IY+ I
Sbjct: 494 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 553
Query: 336 SVGSRRKTSQEPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGRESVGF 515
++ + ++ + + G + R + G +F + + G + GF
Sbjct: 554 TLDKKACSAIHAVNLRNYLGAECR----TVREEMGDESEEFLQVFDNDISYIEGGTASGF 609
Query: 516 NHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKA 683
+ V + RM++V GK+++++ V + S++ F+L DIYV+ G +A
Sbjct: 610 -YTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQA 664
Score = 33.9 bits (74), Expect = 0.57
Identities = 19/50 (38%), Positives = 23/50 (46%)
Frame = +1
Query: 385 VGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGGNPSVLTTSSRT 534
V L + G RE MG ES FL F ++Y+EGG S T T
Sbjct: 566 VNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGFYTVEDT 615
>U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog
protein.
Length = 1268
Score = 56.0 bits (129), Expect = 1e-07
Identities = 23/57 (40%), Positives = 35/57 (61%)
Frame = +2
Query: 245 HRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTLAWTTSSGAQ 415
H K Y+ D YI+L+T D +L+W+I+YWIG E+T D+ +AI + GA+
Sbjct: 518 HGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAE 574
Score = 42.3 bits (95), Expect = 0.002
Identities = 39/176 (22%), Positives = 80/176 (45%), Gaps = 5/176 (2%)
Frame = +3
Query: 171 NVGRTAGVQIWRIQNFEPIPVAQKDIGKSTKE----IHTSFYGRPRTVA-TIYHGISTTG 335
+VG+ G+ IW+I+NF P+ V + GK + + +F ++ IY+ I
Sbjct: 493 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 552
Query: 336 SVGSRRKTSQEPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGRESVGF 515
++ + ++ + + G + R + G +F + + G + GF
Sbjct: 553 TLDKKACSAIHAVNLRNYLGAECR----TVREEMGDESEEFLQVFDNDISYIEGGTASGF 608
Query: 516 NHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKA 683
+ V + RM++V GK+++++ V + S++ F+L DIYV+ G +A
Sbjct: 609 -YTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQA 663
Score = 33.9 bits (74), Expect = 0.57
Identities = 19/50 (38%), Positives = 23/50 (46%)
Frame = +1
Query: 385 VGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGGNPSVLTTSSRT 534
V L + G RE MG ES FL F ++Y+EGG S T T
Sbjct: 565 VNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGFYTVEDT 614
>BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog
(Drosophila) protein.
Length = 1269
Score = 56.0 bits (129), Expect = 1e-07
Identities = 23/57 (40%), Positives = 35/57 (61%)
Frame = +2
Query: 245 HRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTLAWTTSSGAQ 415
H K Y+ D YI+L+T D +L+W+I+YWIG E+T D+ +AI + GA+
Sbjct: 519 HGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAE 575
Score = 42.3 bits (95), Expect = 0.002
Identities = 39/176 (22%), Positives = 80/176 (45%), Gaps = 5/176 (2%)
Frame = +3
Query: 171 NVGRTAGVQIWRIQNFEPIPVAQKDIGKSTKE----IHTSFYGRPRTVA-TIYHGISTTG 335
+VG+ G+ IW+I+NF P+ V + GK + + +F ++ IY+ I
Sbjct: 494 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 553
Query: 336 SVGSRRKTSQEPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGRESVGF 515
++ + ++ + + G + R + G +F + + G + GF
Sbjct: 554 TLDKKACSAIHAVNLRNYLGAECR----TVREEMGDESEEFLQVFDNDISYIEGGTASGF 609
Query: 516 NHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKA 683
+ V + RM++V GK+++++ V + S++ F+L DIYV+ G +A
Sbjct: 610 -YTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQA 664
Score = 33.9 bits (74), Expect = 0.57
Identities = 19/50 (38%), Positives = 23/50 (46%)
Frame = +1
Query: 385 VGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGGNPSVLTTSSRT 534
V L + G RE MG ES FL F ++Y+EGG S T T
Sbjct: 566 VNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGFYTVEDT 615
>AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog
variant protein.
Length = 1101
Score = 56.0 bits (129), Expect = 1e-07
Identities = 23/57 (40%), Positives = 35/57 (61%)
Frame = +2
Query: 245 HRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTLAWTTSSGAQ 415
H K Y+ D YI+L+T D +L+W+I+YWIG E+T D+ +AI + GA+
Sbjct: 506 HGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSAIHAVNLRNYLGAE 562
Score = 42.3 bits (95), Expect = 0.002
Identities = 39/176 (22%), Positives = 80/176 (45%), Gaps = 5/176 (2%)
Frame = +3
Query: 171 NVGRTAGVQIWRIQNFEPIPVAQKDIGKSTKE----IHTSFYGRPRTVA-TIYHGISTTG 335
+VG+ G+ IW+I+NF P+ V + GK + + +F ++ IY+ I
Sbjct: 481 DVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEA 540
Query: 336 SVGSRRKTSQEPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGRESVGF 515
++ + ++ + + G + R + G +F + + G + GF
Sbjct: 541 TLDKKACSAIHAVNLRNYLGAECR----TVREEMGDESEEFLQVFDNDISYIEGGTASGF 596
Query: 516 NHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKA 683
+ V + RM++V GK+++++ V + S++ F+L DIYV+ G +A
Sbjct: 597 -YTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQA 651
Score = 33.9 bits (74), Expect = 0.57
Identities = 19/50 (38%), Positives = 23/50 (46%)
Frame = +1
Query: 385 VGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGGNPSVLTTSSRT 534
V L + G RE MG ES FL F ++Y+EGG S T T
Sbjct: 553 VNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGGTASGFYTVEDT 602
>X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for
villin. ).
Length = 827
Score = 52.8 bits (121), Expect = 1e-06
Identities = 42/174 (24%), Positives = 72/174 (41%)
Frame = +3
Query: 183 TAGVQIWRIQNFEPIPVAQKDIGKSTKEIHTSFYGRPRTVATIYHGISTTGSVGSRRKTS 362
T G+QIWRI+ + +PV G +T +++ + I S
Sbjct: 16 TPGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQ 75
Query: 363 QEPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGRESVGFNHVVTNAGA 542
+ ++G + G+ F L + G + G HV TN+
Sbjct: 76 GAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYD 135
Query: 543 QKRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLK 704
+R+ VKGKR+V +V+ S N+GD F+L L I + G ++ +E+L+
Sbjct: 136 VQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLR 189
Score = 51.6 bits (118), Expect = 3e-06
Identities = 24/43 (55%), Positives = 32/43 (74%)
Frame = +2
Query: 257 YKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAIST 385
+ GD YIIL + ++LS+DIHYWIG++S+ DE GAAAI T
Sbjct: 41 FDGDCYIIL-AIHKTASSLSYDIHYWIGQDSSLDEQGAAAIYT 82
Score = 39.9 bits (89), Expect = 0.009
Identities = 18/41 (43%), Positives = 23/41 (56%)
Frame = +1
Query: 379 FNVGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGG 501
+ +DD G AVQHRE G+ES F YF+ L +GG
Sbjct: 81 YTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKGG 121
>U12026-1|AAA92670.1| 172|Homo sapiens Cap-G protein.
Length = 172
Score = 52.8 bits (121), Expect = 1e-06
Identities = 39/155 (25%), Positives = 67/155 (43%), Gaps = 2/155 (1%)
Frame = +3
Query: 189 GVQIWRIQNFEPIPVAQKDIGKS-TKEIHTSFYGRPRTVATIYHGISTTGSVGSRRKTSQ 365
G+ +WR++ +P+PVAQ++ G + + + + P V+ ++ I S + +
Sbjct: 20 GLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHLHLWIGQQSSRDEQGACAV 79
Query: 366 EPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGRESVGFNHVVTNAGAQ 545
G + H G+ FP L G F+ T A A
Sbjct: 80 LAVHLNTLLGERPVQHR----EVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTGAPAA 135
Query: 546 -KRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSL 647
K+++QVKGK+++R + S N GDCF+L L
Sbjct: 136 IKKLYQVKGKKNIRATERALNWDSFNTGDCFILDL 170
Score = 44.0 bits (99), Expect = 5e-04
Identities = 23/48 (47%), Positives = 27/48 (56%)
Frame = +1
Query: 385 VGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGGNPSVLTTSS 528
V L+ G VQHRE G+ES LF+SYF L Y EGG S +S
Sbjct: 82 VHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTS 129
Score = 39.5 bits (88), Expect = 0.011
Identities = 19/57 (33%), Positives = 31/57 (54%)
Frame = +2
Query: 239 EGHRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAISTLAWTTSSG 409
E + GDSY++L + ++L H WIG++S++DE GA A+ + T G
Sbjct: 37 ENQGVFFSGDSYLVLHNGPEEVSHL----HLWIGQQSSRDEQGACAVLAVHLNTLLG 89
>BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein.
Length = 812
Score = 52.8 bits (121), Expect = 1e-06
Identities = 27/70 (38%), Positives = 40/70 (57%)
Frame = +3
Query: 495 GRESVGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVG 674
G + G HV TN KR+ VKGKR++R +V+ S N+GD F+L L I + G
Sbjct: 110 GGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNG 169
Query: 675 EKAKNVEKLK 704
++ + E+LK
Sbjct: 170 PESNSGERLK 179
Score = 51.6 bits (118), Expect = 3e-06
Identities = 24/47 (51%), Positives = 32/47 (68%)
Frame = +2
Query: 245 HRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAIST 385
H Y+GD Y+IL T + + LS DIH+WIG++S+QDE AAI T
Sbjct: 27 HGNFYEGDCYVILSTRRVA-SLLSQDIHFWIGKDSSQDEQSCAAIYT 72
Score = 44.4 bits (100), Expect = 4e-04
Identities = 19/41 (46%), Positives = 24/41 (58%)
Frame = +1
Query: 379 FNVGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGG 501
+ LDD GG+ VQHRE HES F YF+ + Y +GG
Sbjct: 71 YTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGG 111
Score = 35.1 bits (77), Expect = 0.25
Identities = 46/179 (25%), Positives = 74/179 (41%), Gaps = 10/179 (5%)
Frame = +3
Query: 192 VQIWRIQNFEPIPVAQKDI-----GKSTKEIHT-SFYGRPRTVATIYHG--ISTTGSVGS 347
V++WRI+N E +PV + G ++T G+P + I+ G S S
Sbjct: 390 VEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNGKPHHILYIWQGRHASQDELAAS 449
Query: 348 RRKTSQEPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGRESVGFNHVV 527
+ + QF QVR G PR F+ IF L +F G S N
Sbjct: 450 AYQAVEVDRQFD-GAAVQVRVRMGTEPRH------FM-AIFKGKLVIFEGGTSRKGN--- 498
Query: 528 TNAGAQKRMFQVKG--KRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEK 698
R+FQ+ G K + + +V +S+N D F+L + Y++ G+ + E+
Sbjct: 499 AEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYLWYGKGSSGDER 557
Score = 33.1 bits (72), Expect = 0.99
Identities = 17/39 (43%), Positives = 22/39 (56%)
Frame = +1
Query: 385 VGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGG 501
V +D +F G AVQ R MG E F++ F+ L EGG
Sbjct: 454 VEVDRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVIFEGG 492
>BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein.
Length = 421
Score = 52.8 bits (121), Expect = 1e-06
Identities = 42/174 (24%), Positives = 72/174 (41%)
Frame = +3
Query: 183 TAGVQIWRIQNFEPIPVAQKDIGKSTKEIHTSFYGRPRTVATIYHGISTTGSVGSRRKTS 362
T G+QIWRI+ + +PV G +T +++ + I S
Sbjct: 16 TPGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQ 75
Query: 363 QEPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGRESVGFNHVVTNAGA 542
+ ++G + G+ F L + G + G HV TN+
Sbjct: 76 GAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYD 135
Query: 543 QKRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLK 704
+R+ VKGKR+V +V+ S N+GD F+L L I + G ++ +E+L+
Sbjct: 136 VQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLR 189
Score = 51.6 bits (118), Expect = 3e-06
Identities = 24/43 (55%), Positives = 32/43 (74%)
Frame = +2
Query: 257 YKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAIST 385
+ GD YIIL + ++LS+DIHYWIG++S+ DE GAAAI T
Sbjct: 41 FDGDCYIIL-AIHKTASSLSYDIHYWIGQDSSLDEQGAAAIYT 82
Score = 39.9 bits (89), Expect = 0.009
Identities = 18/41 (43%), Positives = 23/41 (56%)
Frame = +1
Query: 379 FNVGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGG 501
+ +DD G AVQHRE G+ES F YF+ L +GG
Sbjct: 81 YTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKGG 121
>AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein.
Length = 827
Score = 52.8 bits (121), Expect = 1e-06
Identities = 42/174 (24%), Positives = 72/174 (41%)
Frame = +3
Query: 183 TAGVQIWRIQNFEPIPVAQKDIGKSTKEIHTSFYGRPRTVATIYHGISTTGSVGSRRKTS 362
T G+QIWRI+ + +PV G +T +++ + I S
Sbjct: 16 TPGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQ 75
Query: 363 QEPPQFQRWPGRQVRGHSGPAPRDHGSRKCFVPIIFPDTLDLFGGRESVGFNHVVTNAGA 542
+ ++G + G+ F L + G + G HV TN+
Sbjct: 76 GAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYD 135
Query: 543 QKRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLK 704
+R+ VKGKR+V +V+ S N+GD F+L L I + G ++ +E+L+
Sbjct: 136 VQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLR 189
Score = 51.6 bits (118), Expect = 3e-06
Identities = 24/43 (55%), Positives = 32/43 (74%)
Frame = +2
Query: 257 YKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAIST 385
+ GD YIIL + ++LS+DIHYWIG++S+ DE GAAAI T
Sbjct: 41 FDGDCYIIL-AIHKTASSLSYDIHYWIGQDSSLDEQGAAAIYT 82
Score = 39.9 bits (89), Expect = 0.009
Identities = 18/41 (43%), Positives = 23/41 (56%)
Frame = +1
Query: 379 FNVGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGG 501
+ +DD G AVQHRE G+ES F YF+ L +GG
Sbjct: 81 YTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKGG 121
>AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein.
Length = 819
Score = 52.8 bits (121), Expect = 1e-06
Identities = 27/70 (38%), Positives = 40/70 (57%)
Frame = +3
Query: 495 GRESVGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVG 674
G + G HV TN KR+ VKGKR++R +V+ S N+GD F+L L I + G
Sbjct: 117 GGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNG 176
Query: 675 EKAKNVEKLK 704
++ + E+LK
Sbjct: 177 PESNSGERLK 186
Score = 51.6 bits (118), Expect = 3e-06
Identities = 24/47 (51%), Positives = 32/47 (68%)
Frame = +2
Query: 245 HRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAIST 385
H Y+GD Y+IL T + + LS DIH+WIG++S+QDE AAI T
Sbjct: 34 HGNFYEGDCYVILSTRRVA-SLLSQDIHFWIGKDSSQDEQSCAAIYT 79
Score = 44.4 bits (100), Expect = 4e-04
Identities = 19/41 (46%), Positives = 24/41 (58%)
Frame = +1
Query: 379 FNVGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGG 501
+ LDD GG+ VQHRE HES F YF+ + Y +GG
Sbjct: 78 YTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGG 118
Score = 33.1 bits (72), Expect = 0.99
Identities = 17/39 (43%), Positives = 22/39 (56%)
Frame = +1
Query: 385 VGLDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLEGG 501
V +D +F G AVQ R MG E F++ F+ L EGG
Sbjct: 461 VEVDRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVIFEGG 499
>AL160060-2|CAH71300.1| 2214|Homo sapiens supervillin protein.
Length = 2214
Score = 51.2 bits (117), Expect = 4e-06
Identities = 21/51 (41%), Positives = 36/51 (70%)
Frame = +3
Query: 552 MFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLK 704
+ Q+KG+R V+ R V+P+ +++N GDCF+L + +++VGE A +EK K
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAK 1495
>AL160060-1|CAH71301.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 51.2 bits (117), Expect = 4e-06
Identities = 21/51 (41%), Positives = 36/51 (70%)
Frame = +3
Query: 552 MFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLK 704
+ Q+KG+R V+ R V+P+ +++N GDCF+L + +++VGE A +EK K
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAK 1069
>AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein.
Length = 2214
Score = 51.2 bits (117), Expect = 4e-06
Identities = 21/51 (41%), Positives = 36/51 (70%)
Frame = +3
Query: 552 MFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLK 704
+ Q+KG+R V+ R V+P+ +++N GDCF+L + +++VGE A +EK K
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAK 1495
>AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 51.2 bits (117), Expect = 4e-06
Identities = 21/51 (41%), Positives = 36/51 (70%)
Frame = +3
Query: 552 MFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLK 704
+ Q+KG+R V+ R V+P+ +++N GDCF+L + +++VGE A +EK K
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAK 1069
>AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein.
Length = 2214
Score = 51.2 bits (117), Expect = 4e-06
Identities = 21/51 (41%), Positives = 36/51 (70%)
Frame = +3
Query: 552 MFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLK 704
+ Q+KG+R V+ R V+P+ +++N GDCF+L + +++VGE A +EK K
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAK 1495
>AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 51.2 bits (117), Expect = 4e-06
Identities = 21/51 (41%), Positives = 36/51 (70%)
Frame = +3
Query: 552 MFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLK 704
+ Q+KG+R V+ R V+P+ +++N GDCF+L + +++VGE A +EK K
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAK 1069
>AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 51.2 bits (117), Expect = 4e-06
Identities = 21/51 (41%), Positives = 36/51 (70%)
Frame = +3
Query: 552 MFQVKGKRDVRVRQVDPQIASMNKGDCFVLSLDNDIYVFVGEKAKNVEKLK 704
+ Q+KG+R V+ R V+P+ +++N GDCF+L + +++VGE A +EK K
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAK 1069
>X07066-1|CAA30102.1| 69|Homo sapiens protein ( Human gene for
gelsolin exon 4. ).
Length = 69
Score = 39.9 bits (89), Expect = 0.009
Identities = 13/28 (46%), Positives = 20/28 (71%)
Frame = +2
Query: 257 YKGDSYIILRTTSDSRNNLSWDIHYWIG 340
+ GD+Y+IL+T NL +D+HYW+G
Sbjct: 42 FTGDAYVILKTVQLRNGNLQYDLHYWLG 69
Score = 36.7 bits (81), Expect = 0.081
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = +3
Query: 156 HPAFANVGRTAGVQIWRIQNFEPIPV 233
HP F G+ G+QIWR++ F+ +PV
Sbjct: 8 HPEFLKAGKEPGLQIWRVEKFDLVPV 33
>BC075797-1|AAH75797.1| 85|Homo sapiens Unknown (protein for
MGC:87550) protein.
Length = 85
Score = 38.3 bits (85), Expect = 0.026
Identities = 15/32 (46%), Positives = 20/32 (62%)
Frame = +3
Query: 156 HPAFANVGRTAGVQIWRIQNFEPIPVAQKDIG 251
H FA G+ AG+Q+WRI+ E +PV Q G
Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHG 38
Score = 35.1 bits (77), Expect = 0.25
Identities = 12/33 (36%), Positives = 21/33 (63%)
Frame = +2
Query: 245 HRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGR 343
H Y GD+Y++L T SR ++ +H+W+G+
Sbjct: 37 HGDFYVGDAYLVLHTAKTSR-GFTYHLHFWLGK 68
>AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 485
Score = 34.3 bits (75), Expect = 0.43
Identities = 20/45 (44%), Positives = 24/45 (53%)
Frame = +2
Query: 251 KIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQDESGAAAIST 385
+ Y GDSYIIL I+ W G +STQDE A+AI T
Sbjct: 198 QFYGGDSYIILYNYRHGGRQ-GQIIYNWQGAQSTQDEVAASAILT 241
Score = 30.7 bits (66), Expect = 5.3
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Frame = +1
Query: 391 LDDKFGGTAVQHRETMGHESALFLSYF-QTPLTYLEGG 501
LD++ GGT VQ R G E A +S F P+ +GG
Sbjct: 244 LDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGG 281
>AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens
cDNA FLJ90717 fis, clone PLACE1008657, highly similar to
Bovine mRNA for adseverin. ).
Length = 396
Score = 33.1 bits (72), Expect = 0.99
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 8/81 (9%)
Frame = +3
Query: 480 LDLFGGRESVGFNHVVTNAGAQK-----RMFQVKGKRD--VRVRQVDPQIASMNKGDCFV 638
L LF + + + + + G Q R+FQV+ R+ +VD S+N D FV
Sbjct: 164 LSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFV 223
Query: 639 LSL-DNDIYVFVGEKAKNVEK 698
L L N Y++VG+ A E+
Sbjct: 224 LKLPQNSGYIWVGKGASQEEE 244
>AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens
cDNA FLJ14872 fis, clone PLACE1002655, highly similar to
ADSEVERIN. ).
Length = 468
Score = 33.1 bits (72), Expect = 0.99
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 8/81 (9%)
Frame = +3
Query: 480 LDLFGGRESVGFNHVVTNAGAQK-----RMFQVKGKRD--VRVRQVDPQIASMNKGDCFV 638
L LF + + + + + G Q R+FQV+ R+ +VD S+N D FV
Sbjct: 236 LSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFV 295
Query: 639 LSL-DNDIYVFVGEKAKNVEK 698
L L N Y++VG+ A E+
Sbjct: 296 LKLPQNSGYIWVGKGASQEEE 316
>BX537759-1|CAD97828.1| 1763|Homo sapiens hypothetical protein
protein.
Length = 1763
Score = 30.7 bits (66), Expect = 5.3
Identities = 23/97 (23%), Positives = 46/97 (47%)
Frame = +2
Query: 179 QNSRCANMENTELRTNTRCSEGHRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQD 358
QN + EL+ + E HR++ GD Y + SD+ +L +D + +S +
Sbjct: 1549 QNDKLLQSLRVELKAYEKLDEEHRRLRDGDKYPM---ESDNSFDL-FDSSQAVTPKSVSE 1604
Query: 359 ESGAAAISTLAWTTSSGAQRSSTERPWVTKVLCSYHI 469
+ T + + SG+ S+T P V++++ +H+
Sbjct: 1605 TPPLSGNDTDSLSCDSGS--SATSTPCVSRLVTGHHL 1639
>BC146782-1|AAI46783.1| 1814|Homo sapiens CDK5 regulatory subunit
associated protein 2 protein.
Length = 1814
Score = 30.7 bits (66), Expect = 5.3
Identities = 23/97 (23%), Positives = 46/97 (47%)
Frame = +2
Query: 179 QNSRCANMENTELRTNTRCSEGHRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQD 358
QN + EL+ + E HR++ GD Y + SD+ +L +D + +S +
Sbjct: 1549 QNDKLLQSLRVELKAYEKLDEEHRRLRDGDKYPM---ESDNSFDL-FDSSQAVTPKSVSE 1604
Query: 359 ESGAAAISTLAWTTSSGAQRSSTERPWVTKVLCSYHI 469
+ T + + SG+ S+T P V++++ +H+
Sbjct: 1605 TPPLSGNDTDSLSCDSGS--SATSTPCVSRLVTGHHL 1639
>BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin
(amyloidosis, Finnish type) protein.
Length = 285
Score = 30.7 bits (66), Expect = 5.3
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Frame = +1
Query: 391 LDDKFGGTAVQHRETMGHESALFLSYF-QTPLTYLEGG 501
LD++ GGT VQ R G E A +S F P+ +GG
Sbjct: 16 LDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGG 53
>AL353736-4|CAI40656.1| 400|Homo sapiens CDK5 regulatory subunit
associated protein 2 protein.
Length = 400
Score = 30.7 bits (66), Expect = 5.3
Identities = 23/97 (23%), Positives = 46/97 (47%)
Frame = +2
Query: 179 QNSRCANMENTELRTNTRCSEGHRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQD 358
QN + EL+ + E HR++ GD Y + SD+ +L +D + +S +
Sbjct: 135 QNDKLLQSLRVELKAYEKLDEEHRRLRDGDKYPM---ESDNSFDL-FDSSQAVTPKSVSE 190
Query: 359 ESGAAAISTLAWTTSSGAQRSSTERPWVTKVLCSYHI 469
+ T + + SG+ S+T P V++++ +H+
Sbjct: 191 TPPLSGNDTDSLSCDSGS--SATSTPCVSRLVTGHHL 225
>AK025867-1|BAB15263.1| 350|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22214 fis, clone HRC01534. ).
Length = 350
Score = 30.7 bits (66), Expect = 5.3
Identities = 23/97 (23%), Positives = 46/97 (47%)
Frame = +2
Query: 179 QNSRCANMENTELRTNTRCSEGHRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQD 358
QN + EL+ + E HR++ GD Y + SD+ +L +D + +S +
Sbjct: 85 QNDKLLQSLRVELKAYEKLDEEHRRLRDGDKYPM---ESDNSFDL-FDSSQAVTPKSVSE 140
Query: 359 ESGAAAISTLAWTTSSGAQRSSTERPWVTKVLCSYHI 469
+ T + + SG+ S+T P V++++ +H+
Sbjct: 141 TPPLSGNDTDSLSCDSGS--SATSTPCVSRLVTGHHL 175
>AB046853-1|BAB13459.2| 1852|Homo sapiens KIAA1633 protein protein.
Length = 1852
Score = 30.7 bits (66), Expect = 5.3
Identities = 23/97 (23%), Positives = 46/97 (47%)
Frame = +2
Query: 179 QNSRCANMENTELRTNTRCSEGHRKIYKGDSYIILRTTSDSRNNLSWDIHYWIGRESTQD 358
QN + EL+ + E HR++ GD Y + SD+ +L +D + +S +
Sbjct: 1587 QNDKLLQSLRVELKAYEKLDEEHRRLRDGDKYPM---ESDNSFDL-FDSSQAVTPKSVSE 1642
Query: 359 ESGAAAISTLAWTTSSGAQRSSTERPWVTKVLCSYHI 469
+ T + + SG+ S+T P V++++ +H+
Sbjct: 1643 TPPLSGNDTDSLSCDSGS--SATSTPCVSRLVTGHHL 1677
>D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein.
Length = 686
Score = 30.3 bits (65), Expect = 7.0
Identities = 15/35 (42%), Positives = 18/35 (51%)
Frame = +1
Query: 391 LDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLE 495
LD +GG VQ TMG E FL+ FQ L +
Sbjct: 289 LDVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVIFQ 323
>BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein.
Length = 672
Score = 30.3 bits (65), Expect = 7.0
Identities = 15/35 (42%), Positives = 18/35 (51%)
Frame = +1
Query: 391 LDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLE 495
LD +GG VQ TMG E FL+ FQ L +
Sbjct: 275 LDVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVIFQ 309
>BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein.
Length = 686
Score = 30.3 bits (65), Expect = 7.0
Identities = 15/35 (42%), Positives = 18/35 (51%)
Frame = +1
Query: 391 LDDKFGGTAVQHRETMGHESALFLSYFQTPLTYLE 495
LD +GG VQ TMG E FL+ FQ L +
Sbjct: 289 LDVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVIFQ 323
>AB209582-1|BAD92819.1| 272|Homo sapiens regulator of G-protein
signalling 11 isoform 1 variant protein.
Length = 272
Score = 29.9 bits (64), Expect = 9.3
Identities = 24/85 (28%), Positives = 33/85 (38%), Gaps = 1/85 (1%)
Frame = +3
Query: 216 FEPIPVAQKDIGKSTKEIHTSFYGRPRTVATIYHGISTTGSVGSRRKTSQEPPQFQRWPG 395
F P+P A GK + + + Y G+ G V SR S P Q Q+ P
Sbjct: 174 FSPLPPAALGAGKWSGGDEGAGGEEGGSSPEQYQGLLGIGGVTSRVTASDRPQQIQQPPS 233
Query: 396 R-QVRGHSGPAPRDHGSRKCFVPII 467
R + GP R+H S P +
Sbjct: 234 RWRPPEPEGPDQREHLSPAAAKPFV 258
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 109,716,750
Number of Sequences: 237096
Number of extensions: 2650150
Number of successful extensions: 10201
Number of sequences better than 10.0: 47
Number of HSP's better than 10.0 without gapping: 9694
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10184
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8175213644
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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