Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fprWP14_F_C12
(645 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC030230-1|AAH30230.2| 574|Homo sapiens aminolevulinate, delta-... 100 9e-21
AL020991-1|CAI43125.1| 550|Homo sapiens aminolevulinate, delta-... 100 9e-21
X56351-1|CAA39794.1| 640|Homo sapiens delta- aminolevulinate sy... 97 5e-20
BC011798-1|AAH11798.1| 640|Homo sapiens aminolevulinate, delta-... 97 5e-20
AY260745-1|AAP94018.1| 640|Homo sapiens migration-inducing prot... 97 5e-20
AB063322-1|BAB93514.1| 640|Homo sapiens aminolevulinate delta-s... 97 5e-20
Y00451-1|CAA68506.1| 642|Homo sapiens protein ( Human mRNA for ... 95 3e-19
X60364-1|CAA42916.1| 587|Homo sapiens 5-aminolevulinate synthas... 95 3e-19
AL020991-2|CAA15886.1| 587|Homo sapiens aminolevulinate, delta-... 95 3e-19
AF068624-1|AAC39838.1| 587|Homo sapiens 5-aminolevulinate synth... 95 3e-19
X56352-1|CAA39795.1| 582|Homo sapiens delta-aminolevulinate syn... 93 6e-19
AY190322-1|AAO37821.1| 73|Homo sapiens 5-aminolevulinate synth... 67 6e-11
Z97630-2|CAB42830.1| 419|Homo sapiens glycine C-acetyltransfera... 45 2e-04
BC014457-1|AAH14457.1| 419|Homo sapiens glycine C-acetyltransfe... 45 2e-04
AK123190-1|BAC85552.1| 248|Homo sapiens .1.29). protein. 45 2e-04
AF077740-1|AAC27720.1| 419|Homo sapiens 2-amino-3-ketobutyrate-... 45 2e-04
Y08685-1|CAA69941.1| 473|Homo sapiens serine palmitoyltransfera... 31 4.6
BC068537-1|AAH68537.1| 513|Homo sapiens SPTLC1 protein protein. 31 4.6
AL391219-2|CAH70209.1| 473|Homo sapiens serine palmitoyltransfe... 31 4.6
AL354751-7|CAH69924.1| 473|Homo sapiens serine palmitoyltransfe... 31 4.6
AF286717-1|AAK29328.1| 473|Homo sapiens serine palmitoyltransfe... 31 4.6
AB209757-1|BAD92994.1| 262|Homo sapiens serine palmitoyltransfe... 31 4.6
BC007085-1|AAH07085.1| 143|Homo sapiens serine palmitoyltransfe... 30 8.1
AL354751-6|CAH69923.1| 143|Homo sapiens serine palmitoyltransfe... 30 8.1
>BC030230-1|AAH30230.2| 574|Homo sapiens aminolevulinate, delta-,
synthase 2 (sideroblastic/hypochromic anemia) protein.
Length = 574
Score = 99.5 bits (237), Expect = 9e-21
Identities = 53/125 (42%), Positives = 77/125 (61%), Gaps = 7/125 (5%)
Frame = +2
Query: 287 QNSIISEAPKEMTEDIAEPATP---YHYENFFHDQINAKKRDYSYRVFRKVSRLAADGVY 457
++ I+ +A E+ ED+ T + Y+ FF D+I KK+D++YRVF+ V+R A Y
Sbjct: 105 KSKIVQKAAPEVQEDVKAFKTGNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWA--DAY 162
Query: 458 PKALEGPE----NRRVTVWCANDYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQM 625
P A E ++ V+VWC+NDYLG SRHP V A ++ +G GAGGTRNI+G S+
Sbjct: 163 PFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGVGAGGTRNISGTSKF 222
Query: 626 TEKLE 640
+LE
Sbjct: 223 HVELE 227
>AL020991-1|CAI43125.1| 550|Homo sapiens aminolevulinate, delta-,
synthase 2 (sideroblastic/hypochromic anemia) protein.
Length = 550
Score = 99.5 bits (237), Expect = 9e-21
Identities = 53/125 (42%), Positives = 77/125 (61%), Gaps = 7/125 (5%)
Frame = +2
Query: 287 QNSIISEAPKEMTEDIAEPATP---YHYENFFHDQINAKKRDYSYRVFRKVSRLAADGVY 457
++ I+ +A E+ ED+ T + Y+ FF D+I KK+D++YRVF+ V+R A Y
Sbjct: 81 KSKIVQKAAPEVQEDVKAFKTGNYVFSYDQFFRDKIMEKKQDHTYRVFKTVNRWA--DAY 138
Query: 458 PKALEGPE----NRRVTVWCANDYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQM 625
P A E ++ V+VWC+NDYLG SRHP V A ++ +G GAGGTRNI+G S+
Sbjct: 139 PFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKF 198
Query: 626 TEKLE 640
+LE
Sbjct: 199 HVELE 203
>X56351-1|CAA39794.1| 640|Homo sapiens delta- aminolevulinate
synthase (housekeeping) protein.
Length = 640
Score = 97.1 bits (231), Expect = 5e-20
Identities = 45/111 (40%), Positives = 74/111 (66%), Gaps = 4/111 (3%)
Frame = +2
Query: 320 MTEDIAEPATPYHYENFFHDQINAKKRDYSYRVFRKVSRLAADGVYPKALEGPEN----R 487
+ +++ + + + Y+ FF +I+ KK D++YRVF+ V+R A ++P A + ++ +
Sbjct: 186 LQDNLPKSVSTFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAH--IFPMADDYSDSLITKK 243
Query: 488 RVTVWCANDYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
+V+VWC+NDYLG SRHP V A ++ +K +G GAGGTRNI+G S+ LE
Sbjct: 244 QVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLE 294
>BC011798-1|AAH11798.1| 640|Homo sapiens aminolevulinate, delta-,
synthase 1 protein.
Length = 640
Score = 97.1 bits (231), Expect = 5e-20
Identities = 45/111 (40%), Positives = 74/111 (66%), Gaps = 4/111 (3%)
Frame = +2
Query: 320 MTEDIAEPATPYHYENFFHDQINAKKRDYSYRVFRKVSRLAADGVYPKALEGPEN----R 487
+ +++ + + + Y+ FF +I+ KK D++YRVF+ V+R A ++P A + ++ +
Sbjct: 186 LQDNLPKSVSTFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAH--IFPMADDYSDSLITKK 243
Query: 488 RVTVWCANDYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
+V+VWC+NDYLG SRHP V A ++ +K +G GAGGTRNI+G S+ LE
Sbjct: 244 QVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLE 294
>AY260745-1|AAP94018.1| 640|Homo sapiens migration-inducing protein
4 protein.
Length = 640
Score = 97.1 bits (231), Expect = 5e-20
Identities = 45/111 (40%), Positives = 74/111 (66%), Gaps = 4/111 (3%)
Frame = +2
Query: 320 MTEDIAEPATPYHYENFFHDQINAKKRDYSYRVFRKVSRLAADGVYPKALEGPEN----R 487
+ +++ + + + Y+ FF +I+ KK D++YRVF+ V+R A ++P A + ++ +
Sbjct: 186 LQDNLPKSVSTFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAH--IFPMADDYSDSLITKK 243
Query: 488 RVTVWCANDYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
+V+VWC+NDYLG SRHP V A ++ +K +G GAGGTRNI+G S+ LE
Sbjct: 244 QVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLE 294
>AB063322-1|BAB93514.1| 640|Homo sapiens aminolevulinate
delta-synthase 1 protein.
Length = 640
Score = 97.1 bits (231), Expect = 5e-20
Identities = 45/111 (40%), Positives = 74/111 (66%), Gaps = 4/111 (3%)
Frame = +2
Query: 320 MTEDIAEPATPYHYENFFHDQINAKKRDYSYRVFRKVSRLAADGVYPKALEGPEN----R 487
+ +++ + + + Y+ FF +I+ KK D++YRVF+ V+R A ++P A + ++ +
Sbjct: 186 LQDNLPKSVSTFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAH--IFPMADDYSDSLITKK 243
Query: 488 RVTVWCANDYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
+V+VWC+NDYLG SRHP V A ++ +K +G GAGGTRNI+G S+ LE
Sbjct: 244 QVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLE 294
>Y00451-1|CAA68506.1| 642|Homo sapiens protein ( Human mRNA for
5-aminolevulinate synthase. ).
Length = 642
Score = 94.7 bits (225), Expect = 3e-19
Identities = 44/109 (40%), Positives = 72/109 (66%), Gaps = 4/109 (3%)
Frame = +2
Query: 326 EDIAEPATPYHYENFFHDQINAKKRDYSYRVFRKVSRLAADGVYPKALEGPEN----RRV 493
+++ + + +HY+ FF + + K D++YRVF+ V+R A ++P A + ++ ++V
Sbjct: 190 DNLPKSVSTFHYDRFFEKKSDEKNDDHTYRVFKTVNRRAH--IFPMADDYSDSLITKKQV 247
Query: 494 TVWCANDYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
+VWC+NDYLG SRHP V A ++ +K +G GAGGTRNI+G S+ LE
Sbjct: 248 SVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLE 296
>X60364-1|CAA42916.1| 587|Homo sapiens 5-aminolevulinate synthase
precursor protein.
Length = 587
Score = 94.7 bits (225), Expect = 3e-19
Identities = 47/100 (47%), Positives = 65/100 (65%), Gaps = 4/100 (4%)
Frame = +2
Query: 353 YHYENFFHDQINAKKRDYSYRVFRKVSRLAADGVYPKALEGPE----NRRVTVWCANDYL 520
+ Y+ FF D+I KK+D++YRVF+ V+R A YP A E ++ V+VWC+NDYL
Sbjct: 143 FSYDQFFRDKIMEKKQDHTYRVFKTVNRWA--DAYPFAQHFSEASVASKDVSVWCSNDYL 200
Query: 521 GTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
G SRHP V A ++ +G GAGGTRNI+G S+ +LE
Sbjct: 201 GMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELE 240
>AL020991-2|CAA15886.1| 587|Homo sapiens aminolevulinate, delta-,
synthase 2 (sideroblastic/hypochromic anemia) protein.
Length = 587
Score = 94.7 bits (225), Expect = 3e-19
Identities = 47/100 (47%), Positives = 65/100 (65%), Gaps = 4/100 (4%)
Frame = +2
Query: 353 YHYENFFHDQINAKKRDYSYRVFRKVSRLAADGVYPKALEGPE----NRRVTVWCANDYL 520
+ Y+ FF D+I KK+D++YRVF+ V+R A YP A E ++ V+VWC+NDYL
Sbjct: 143 FSYDQFFRDKIMEKKQDHTYRVFKTVNRWA--DAYPFAQHFSEASVASKDVSVWCSNDYL 200
Query: 521 GTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
G SRHP V A ++ +G GAGGTRNI+G S+ +LE
Sbjct: 201 GMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELE 240
>AF068624-1|AAC39838.1| 587|Homo sapiens 5-aminolevulinate synthase
2 protein.
Length = 587
Score = 94.7 bits (225), Expect = 3e-19
Identities = 47/100 (47%), Positives = 65/100 (65%), Gaps = 4/100 (4%)
Frame = +2
Query: 353 YHYENFFHDQINAKKRDYSYRVFRKVSRLAADGVYPKALEGPE----NRRVTVWCANDYL 520
+ Y+ FF D+I KK+D++YRVF+ V+R A YP A E ++ V+VWC+NDYL
Sbjct: 143 FSYDQFFRDKIMEKKQDHTYRVFKTVNRWA--DAYPFAQHFSEASVASKDVSVWCSNDYL 200
Query: 521 GTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
G SRHP V A ++ +G GAGGTRNI+G S+ +LE
Sbjct: 201 GMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELE 240
>X56352-1|CAA39795.1| 582|Homo sapiens delta-aminolevulinate
synthase (erythroid) protein.
Length = 582
Score = 93.5 bits (222), Expect = 6e-19
Identities = 47/100 (47%), Positives = 65/100 (65%), Gaps = 4/100 (4%)
Frame = +2
Query: 353 YHYENFFHDQINAKKRDYSYRVFRKVSRLAADGVYPKALEGPE----NRRVTVWCANDYL 520
+ Y+ FF D+I KK+D++YRVF+ V+R A YP A E ++ V+VWC+NDYL
Sbjct: 138 FSYDQFFRDKIMEKKQDHTYRVFKTVNRWA--DAYPFAQHFFEASVASKDVSVWCSNDYL 195
Query: 521 GTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
G SRHP V A ++ +G GAGGTRNI+G S+ +LE
Sbjct: 196 GMSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELE 235
>AY190322-1|AAO37821.1| 73|Homo sapiens 5-aminolevulinate synthase
2 protein.
Length = 73
Score = 66.9 bits (156), Expect = 6e-11
Identities = 34/71 (47%), Positives = 46/71 (64%), Gaps = 4/71 (5%)
Frame = +2
Query: 353 YHYENFFHDQINAKKRDYSYRVFRKVSRLAADGVYPKALEGPE----NRRVTVWCANDYL 520
+ Y+ FF D+I KK+D++YRVF+ V+R A YP A E ++ V+VWC+NDYL
Sbjct: 4 FSYDQFFRDKIIEKKQDHTYRVFKTVNRWA--DAYPFAQHFSEASVASKDVSVWCSNDYL 61
Query: 521 GTSRHPTVQDA 553
G SRHP V A
Sbjct: 62 GMSRHPQVLQA 72
>Z97630-2|CAB42830.1| 419|Homo sapiens glycine C-acetyltransferase
(2-amino-3-ketobutyrate coenzyme A ligase) protein.
Length = 419
Score = 45.2 bits (102), Expect = 2e-04
Identities = 19/47 (40%), Positives = 27/47 (57%)
Frame = +2
Query: 500 WCANDYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
+CAN+YLG S HP V A + A++ +G G R I G + + LE
Sbjct: 70 FCANNYLGLSSHPEVIQAGLQALEEFGAGLSSVRFICGTQSIHKNLE 116
>BC014457-1|AAH14457.1| 419|Homo sapiens glycine
C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A
ligase) protein.
Length = 419
Score = 45.2 bits (102), Expect = 2e-04
Identities = 19/47 (40%), Positives = 27/47 (57%)
Frame = +2
Query: 500 WCANDYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
+CAN+YLG S HP V A + A++ +G G R I G + + LE
Sbjct: 70 FCANNYLGLSSHPEVIQAGLQALEEFGAGLSSVRFICGTQSIHKNLE 116
>AK123190-1|BAC85552.1| 248|Homo sapiens .1.29). protein.
Length = 248
Score = 45.2 bits (102), Expect = 2e-04
Identities = 19/47 (40%), Positives = 27/47 (57%)
Frame = +2
Query: 500 WCANDYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
+CAN+YLG S HP V A + A++ +G G R I G + + LE
Sbjct: 96 FCANNYLGLSSHPEVIQAGLQALEEFGAGLSSVRFICGTQSIHKNLE 142
>AF077740-1|AAC27720.1| 419|Homo sapiens 2-amino-3-ketobutyrate-CoA
ligase protein.
Length = 419
Score = 45.2 bits (102), Expect = 2e-04
Identities = 19/47 (40%), Positives = 27/47 (57%)
Frame = +2
Query: 500 WCANDYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
+CAN+YLG S HP V A + A++ +G G R I G + + LE
Sbjct: 70 FCANNYLGLSSHPEVIQAGLQALEEFGAGLSSVRFICGTQSIHKNLE 116
>Y08685-1|CAA69941.1| 473|Homo sapiens serine palmitoyltransferase,
subunit I protein.
Length = 473
Score = 30.7 bits (66), Expect = 4.6
Identities = 15/43 (34%), Positives = 23/43 (53%)
Frame = +2
Query: 512 DYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
++LG +P V+ AA+ ++K YG G G R G + LE
Sbjct: 107 NFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLE 149
>BC068537-1|AAH68537.1| 513|Homo sapiens SPTLC1 protein protein.
Length = 513
Score = 30.7 bits (66), Expect = 4.6
Identities = 15/43 (34%), Positives = 23/43 (53%)
Frame = +2
Query: 512 DYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
++LG +P V+ AA+ ++K YG G G R G + LE
Sbjct: 107 NFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLE 149
>AL391219-2|CAH70209.1| 473|Homo sapiens serine
palmitoyltransferase, long chain base subunit 1 protein.
Length = 473
Score = 30.7 bits (66), Expect = 4.6
Identities = 15/43 (34%), Positives = 23/43 (53%)
Frame = +2
Query: 512 DYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
++LG +P V+ AA+ ++K YG G G R G + LE
Sbjct: 107 NFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLE 149
>AL354751-7|CAH69924.1| 473|Homo sapiens serine
palmitoyltransferase, long chain base subunit 1 protein.
Length = 473
Score = 30.7 bits (66), Expect = 4.6
Identities = 15/43 (34%), Positives = 23/43 (53%)
Frame = +2
Query: 512 DYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
++LG +P V+ AA+ ++K YG G G R G + LE
Sbjct: 107 NFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLE 149
>AF286717-1|AAK29328.1| 473|Homo sapiens serine
palmitoyltransferase protein.
Length = 473
Score = 30.7 bits (66), Expect = 4.6
Identities = 15/43 (34%), Positives = 23/43 (53%)
Frame = +2
Query: 512 DYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
++LG +P V+ AA+ ++K YG G G R G + LE
Sbjct: 107 NFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLE 149
>AB209757-1|BAD92994.1| 262|Homo sapiens serine
palmitoyltransferase subunit 1 isoform a variant
protein.
Length = 262
Score = 30.7 bits (66), Expect = 4.6
Identities = 15/43 (34%), Positives = 23/43 (53%)
Frame = +2
Query: 512 DYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAGNSQMTEKLE 640
++LG +P V+ AA+ ++K YG G G R G + LE
Sbjct: 102 NFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLE 144
>BC007085-1|AAH07085.1| 143|Homo sapiens serine
palmitoyltransferase, long chain base subunit 1 protein.
Length = 143
Score = 29.9 bits (64), Expect = 8.1
Identities = 13/34 (38%), Positives = 20/34 (58%)
Frame = +2
Query: 512 DYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAG 613
++LG +P V+ AA+ ++K YG G G R G
Sbjct: 107 NFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYG 140
>AL354751-6|CAH69923.1| 143|Homo sapiens serine
palmitoyltransferase, long chain base subunit 1 protein.
Length = 143
Score = 29.9 bits (64), Expect = 8.1
Identities = 13/34 (38%), Positives = 20/34 (58%)
Frame = +2
Query: 512 DYLGTSRHPTVQDAAVNAIKSYGTGAGGTRNIAG 613
++LG +P V+ AA+ ++K YG G G R G
Sbjct: 107 NFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYG 140
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 99,266,080
Number of Sequences: 237096
Number of extensions: 2174941
Number of successful extensions: 5147
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 4987
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5135
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7141427170
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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