Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fprWP14_F_B11
(654 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z46376-1|CAA86511.1| 917|Homo sapiens Human hexokinase II cDNA ... 139 7e-33
Z46354-1|CAA86476.2| 916|Homo sapiens hexokinase II protein. 139 7e-33
BC064369-1|AAH64369.1| 917|Homo sapiens hexokinase 2 protein. 139 7e-33
BC021116-1|AAH21116.1| 917|Homo sapiens hexokinase 2 protein. 139 7e-33
AY623118-1|AAT38114.1| 917|Homo sapiens hexokinase 2 protein. 139 7e-33
AF148513-1|AAD30174.1| 917|Homo sapiens hexokinase II protein. 139 7e-33
AC019069-1|AAX93084.1| 344|Homo sapiens unknown protein. 139 7e-33
BC110505-1|AAI10506.2| 917|Homo sapiens hexokinase domain conta... 137 3e-32
BC110504-1|AAI10505.1| 917|Homo sapiens hexokinase domain conta... 137 3e-32
BC012337-1|AAH12337.1| 677|Homo sapiens HKDC1 protein protein. 137 3e-32
AL596223-3|CAH71500.1| 917|Homo sapiens hexokinase domain conta... 137 3e-32
AK026414-1|BAB15478.1| 325|Homo sapiens protein ( Homo sapiens ... 137 3e-32
AC104135-1|AAY24209.1| 573|Homo sapiens unknown protein. 132 8e-31
M75126-1|AAA52646.1| 917|Homo sapiens hexokinase 1 protein. 130 3e-30
BC008730-1|AAH08730.1| 917|Homo sapiens hexokinase 1 protein. 130 3e-30
AL596223-9|CAH71506.1| 917|Homo sapiens hexokinase 1 protein. 130 3e-30
AF016365-4|AAC15862.1| 917|Homo sapiens hexokinase I protein. 130 3e-30
AB209526-1|BAD92763.1| 949|Homo sapiens hexokinase 1 isoform HK... 130 3e-30
BC021278-1|AAH21278.1| 427|Homo sapiens HKDC1 protein protein. 129 7e-30
AL596223-8|CAH71505.1| 291|Homo sapiens hexokinase 1 protein. 127 3e-29
AF016365-3|AAC15863.1| 916|Homo sapiens hexokinase IR protein. 127 3e-29
AF016365-2|AAF82320.1| 905|Homo sapiens hexokinase 1 isoform td... 127 3e-29
AF016365-1|AAF82319.1| 921|Homo sapiens hexokinase 1 isoform ta... 127 3e-29
M90299-1|AAA52562.1| 465|Homo sapiens glucokinase protein. 126 7e-29
M88011-1|AAA51824.1| 465|Homo sapiens glucokinase protein. 126 7e-29
EU008605-1|ABS31137.1| 465|Homo sapiens glucokinase protein. 126 7e-29
BT007062-1|AAP35711.1| 465|Homo sapiens glucokinase (hexokinase... 126 7e-29
BC001890-1|AAH01890.1| 465|Homo sapiens glucokinase (hexokinase... 126 7e-29
AF041022-1|AAB97680.1| 465|Homo sapiens glucokinase protein. 126 7e-29
AF041022-3|AAB97682.1| 464|Homo sapiens glucokinase protein. 125 1e-28
AF041022-2|AAB97681.1| 466|Homo sapiens glucokinase protein. 125 1e-28
X66957-1|CAA47379.1| 631|Homo sapiens hexokinase type 1 protein. 125 2e-28
M69051-1|AAB59563.1| 464|Homo sapiens glucokinase protein. 124 2e-28
U51333-1|AAC50732.1| 923|Homo sapiens hexokinase III protein. 116 7e-26
BC028129-1|AAH28129.1| 923|Homo sapiens hexokinase 3 (white cel... 116 7e-26
AB208951-1|BAD92188.1| 960|Homo sapiens Hexokinase 3 variant pr... 116 7e-26
U42303-1|AAC50422.1| 566|Homo sapiens ATP:D-hexose 6-phosphotra... 103 4e-22
AL596223-5|CAH71502.1| 139|Homo sapiens hexokinase 1 protein. 97 6e-20
AL596223-7|CAH71504.1| 114|Homo sapiens hexokinase 1 protein. 79 2e-14
AF073786-1|AAC25424.1| 114|Homo sapiens testis-specific hexokin... 79 2e-14
BC121179-1|AAI21180.1| 722|Homo sapiens glucosamine (UDP-N-acet... 30 6.3
AY531128-1|AAS59259.1| 722|Homo sapiens UDP-N-acetylglucosamine... 30 6.3
AY531127-1|AAS59258.1| 722|Homo sapiens UDP-N-acetylglucosamine... 30 6.3
AY531126-1|AAS59257.1| 722|Homo sapiens UDP-N-acetylglucosamine... 30 6.3
AM697709-1|CAM91425.1| 681|Homo sapiens UDP-N-acetylglucosamine... 30 6.3
AM697708-1|CAM91424.1| 753|Homo sapiens UDP-N-acetylglucosamine... 30 6.3
AL158830-7|CAD13389.1| 722|Homo sapiens glucosamine (UDP-N-acet... 30 6.3
AJ238764-1|CAB42607.1| 722|Homo sapiens UDP-N-acetylglucosamine... 30 6.3
AF317635-1|AAG31661.1| 722|Homo sapiens UDP-N-acetylglucosamine... 30 6.3
AF155663-1|AAD38197.1| 722|Homo sapiens UDP-N-acetylglucosamine... 30 6.3
AF051852-1|AAD32251.1| 722|Homo sapiens UDP-N-acetylglucosamine... 30 6.3
>Z46376-1|CAA86511.1| 917|Homo sapiens Human hexokinase II cDNA
protein.
Length = 917
Score = 139 bits (337), Expect = 7e-33
Identities = 68/152 (44%), Positives = 101/152 (66%), Gaps = 3/152 (1%)
Frame = +1
Query: 127 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKE 306
D +Q++ + ++++D+ + EI R +++KGL H A VK T+++ P+G E
Sbjct: 17 DQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTE 76
Query: 307 RGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECLAN 477
G+FLALDLGGTNFRVL + + +N +M+++IYAIP+ IM G+G LFDHIAECLAN
Sbjct: 77 HGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 136
Query: 478 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVL 573
FM + + +++L LGFTFSFP Q L + L
Sbjct: 137 FMDKLQIKDKKLPLGFTFSFPCHQTKLDESFL 168
Score = 132 bits (320), Expect = 8e-31
Identities = 68/164 (41%), Positives = 103/164 (62%), Gaps = 3/164 (1%)
Frame = +1
Query: 121 VVDNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNG 300
+ D + ++ E L+++ Q+ E+ R+ ++++GLS+ H A VK TY+ P+G
Sbjct: 463 LADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDG 522
Query: 301 KERGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECL 471
E+G FLALDLGGTNFRVL++ + + +M +KIYAIP+ +M GTG LFDHI +C+
Sbjct: 523 TEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCI 582
Query: 472 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
A+F++ G+ L LGFTFSFP +Q L + +L K F S
Sbjct: 583 ADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKAS 626
>Z46354-1|CAA86476.2| 916|Homo sapiens hexokinase II protein.
Length = 916
Score = 139 bits (337), Expect = 7e-33
Identities = 68/152 (44%), Positives = 101/152 (66%), Gaps = 3/152 (1%)
Frame = +1
Query: 127 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKE 306
D +Q++ + ++++D+ + EI R +++KGL H A VK T+++ P+G E
Sbjct: 17 DQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTE 76
Query: 307 RGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECLAN 477
G+FLALDLGGTNFRVL + + +N +M+++IYAIP+ IM G+G LFDHIAECLAN
Sbjct: 77 HGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 136
Query: 478 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVL 573
FM + + +++L LGFTFSFP Q L + L
Sbjct: 137 FMDKLHIKDKKLPLGFTFSFPCHQTKLDESFL 168
Score = 132 bits (320), Expect = 8e-31
Identities = 68/164 (41%), Positives = 103/164 (62%), Gaps = 3/164 (1%)
Frame = +1
Query: 121 VVDNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNG 300
+ D + ++ E L+++ Q+ E+ R+ ++++GLS+ H A VK TY+ P+G
Sbjct: 463 LADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDG 522
Query: 301 KERGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECL 471
E+G FLALDLGGTNFRVL++ + + +M +KIYAIP+ +M GTG LFDHI +C+
Sbjct: 523 TEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCI 582
Query: 472 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
A+F++ G+ L LGFTFSFP +Q L + +L K F S
Sbjct: 583 ADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKAS 626
>BC064369-1|AAH64369.1| 917|Homo sapiens hexokinase 2 protein.
Length = 917
Score = 139 bits (337), Expect = 7e-33
Identities = 68/152 (44%), Positives = 101/152 (66%), Gaps = 3/152 (1%)
Frame = +1
Query: 127 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKE 306
D +Q++ + ++++D+ + EI R +++KGL H A VK T+++ P+G E
Sbjct: 17 DQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTE 76
Query: 307 RGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECLAN 477
G+FLALDLGGTNFRVL + + +N +M+++IYAIP+ IM G+G LFDHIAECLAN
Sbjct: 77 HGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 136
Query: 478 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVL 573
FM + + +++L LGFTFSFP Q L + L
Sbjct: 137 FMDKLQIKDKKLPLGFTFSFPCHQTKLDESFL 168
Score = 132 bits (320), Expect = 8e-31
Identities = 68/164 (41%), Positives = 103/164 (62%), Gaps = 3/164 (1%)
Frame = +1
Query: 121 VVDNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNG 300
+ D + ++ E L+++ Q+ E+ R+ ++++GLS+ H A VK TY+ P+G
Sbjct: 463 LADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDG 522
Query: 301 KERGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECL 471
E+G FLALDLGGTNFRVL++ + + +M +KIYAIP+ +M GTG LFDHI +C+
Sbjct: 523 TEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCI 582
Query: 472 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
A+F++ G+ L LGFTFSFP +Q L + +L K F S
Sbjct: 583 ADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKAS 626
>BC021116-1|AAH21116.1| 917|Homo sapiens hexokinase 2 protein.
Length = 917
Score = 139 bits (337), Expect = 7e-33
Identities = 68/152 (44%), Positives = 101/152 (66%), Gaps = 3/152 (1%)
Frame = +1
Query: 127 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKE 306
D +Q++ + ++++D+ + EI R +++KGL H A VK T+++ P+G E
Sbjct: 17 DQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTE 76
Query: 307 RGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECLAN 477
G+FLALDLGGTNFRVL + + +N +M+++IYAIP+ IM G+G LFDHIAECLAN
Sbjct: 77 HGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 136
Query: 478 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVL 573
FM + + +++L LGFTFSFP Q L + L
Sbjct: 137 FMDKLQIKDKKLPLGFTFSFPCHQTKLDESFL 168
Score = 132 bits (320), Expect = 8e-31
Identities = 68/164 (41%), Positives = 103/164 (62%), Gaps = 3/164 (1%)
Frame = +1
Query: 121 VVDNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNG 300
+ D + ++ E L+++ Q+ E+ R+ ++++GLS+ H A VK TY+ P+G
Sbjct: 463 LADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDG 522
Query: 301 KERGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECL 471
E+G FLALDLGGTNFRVL++ + + +M +KIYAIP+ +M GTG LFDHI +C+
Sbjct: 523 TEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCI 582
Query: 472 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
A+F++ G+ L LGFTFSFP +Q L + +L K F S
Sbjct: 583 ADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKAS 626
>AY623118-1|AAT38114.1| 917|Homo sapiens hexokinase 2 protein.
Length = 917
Score = 139 bits (337), Expect = 7e-33
Identities = 68/152 (44%), Positives = 101/152 (66%), Gaps = 3/152 (1%)
Frame = +1
Query: 127 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKE 306
D +Q++ + ++++D+ + EI R +++KGL H A VK T+++ P+G E
Sbjct: 17 DQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTE 76
Query: 307 RGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECLAN 477
G+FLALDLGGTNFRVL + + +N +M+++IYAIP+ IM G+G LFDHIAECLAN
Sbjct: 77 HGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 136
Query: 478 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVL 573
FM + + +++L LGFTFSFP Q L + L
Sbjct: 137 FMDKLQIKDKKLPLGFTFSFPCHQTKLDESFL 168
Score = 132 bits (320), Expect = 8e-31
Identities = 68/164 (41%), Positives = 103/164 (62%), Gaps = 3/164 (1%)
Frame = +1
Query: 121 VVDNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNG 300
+ D + ++ E L+++ Q+ E+ R+ ++++GLS+ H A VK TY+ P+G
Sbjct: 463 LADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDG 522
Query: 301 KERGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECL 471
E+G FLALDLGGTNFRVL++ + + +M +KIYAIP+ +M GTG LFDHI +C+
Sbjct: 523 TEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCI 582
Query: 472 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
A+F++ G+ L LGFTFSFP +Q L + +L K F S
Sbjct: 583 ADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKAS 626
>AF148513-1|AAD30174.1| 917|Homo sapiens hexokinase II protein.
Length = 917
Score = 139 bits (337), Expect = 7e-33
Identities = 68/152 (44%), Positives = 101/152 (66%), Gaps = 3/152 (1%)
Frame = +1
Query: 127 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKE 306
D +Q++ + ++++D+ + EI R +++KGL H A VK T+++ P+G E
Sbjct: 17 DQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTE 76
Query: 307 RGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECLAN 477
G+FLALDLGGTNFRVL + + +N +M+++IYAIP+ IM G+G LFDHIAECLAN
Sbjct: 77 HGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 136
Query: 478 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVL 573
FM + + +++L LGFTFSFP Q L + L
Sbjct: 137 FMDKLQIKDKKLPLGFTFSFPCHQTKLDESFL 168
Score = 132 bits (320), Expect = 8e-31
Identities = 68/164 (41%), Positives = 103/164 (62%), Gaps = 3/164 (1%)
Frame = +1
Query: 121 VVDNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNG 300
+ D + ++ E L+++ Q+ E+ R+ ++++GLS+ H A VK TY+ P+G
Sbjct: 463 LADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDG 522
Query: 301 KERGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECL 471
E+G FLALDLGGTNFRVL++ + + +M +KIYAIP+ +M GTG LFDHI +C+
Sbjct: 523 TEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCI 582
Query: 472 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
A+F++ G+ L LGFTFSFP +Q L + +L K F S
Sbjct: 583 ADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKAS 626
>AC019069-1|AAX93084.1| 344|Homo sapiens unknown protein.
Length = 344
Score = 139 bits (337), Expect = 7e-33
Identities = 68/152 (44%), Positives = 101/152 (66%), Gaps = 3/152 (1%)
Frame = +1
Query: 127 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKE 306
D +Q++ + ++++D+ + EI R +++KGL H A VK T+++ P+G E
Sbjct: 17 DQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTE 76
Query: 307 RGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECLAN 477
G+FLALDLGGTNFRVL + + +N +M+++IYAIP+ IM G+G LFDHIAECLAN
Sbjct: 77 HGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSGTQLFDHIAECLAN 136
Query: 478 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVL 573
FM + + +++L LGFTFSFP Q L + L
Sbjct: 137 FMDKLQIKDKKLPLGFTFSFPCHQTKLDESFL 168
>BC110505-1|AAI10506.2| 917|Homo sapiens hexokinase domain
containing 1 protein.
Length = 917
Score = 137 bits (332), Expect = 3e-32
Identities = 65/140 (46%), Positives = 94/140 (67%), Gaps = 2/140 (1%)
Frame = +1
Query: 160 VLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFLALDLGG 339
+ ++T +Q+ ++ ++ +L+ GL + H ATV+ TY+ LP+G E+GKFLALDLGG
Sbjct: 476 LFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGG 535
Query: 340 TNFRVLIINL--GENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERL 513
TNFRVL++ + G M +KI+AIP IM GTG LFDHI +C+A+F+ G+ L
Sbjct: 536 TNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASL 595
Query: 514 ALGFTFSFPLKQLGLTKGVL 573
LGFTFSFP +Q+ + KG L
Sbjct: 596 PLGFTFSFPCRQMSIDKGTL 615
Score = 124 bits (298), Expect = 4e-28
Identities = 58/152 (38%), Positives = 98/152 (64%), Gaps = 3/152 (1%)
Frame = +1
Query: 127 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKE 306
D ++++ ++++D + +IM R +++KGL++ + A VK T+++ +P+G E
Sbjct: 17 DQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSE 76
Query: 307 RGKFLALDLGGTNFRVLIINL---GENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLAN 477
G+FL+LDLGG+ FRVL + + G+ H M+S+ Y P I+ G G LF+++A+CLA+
Sbjct: 77 NGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLAD 136
Query: 478 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVL 573
FMK + ++L LG TFSFP +Q L +GVL
Sbjct: 137 FMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVL 168
>BC110504-1|AAI10505.1| 917|Homo sapiens hexokinase domain
containing 1 protein.
Length = 917
Score = 137 bits (332), Expect = 3e-32
Identities = 65/140 (46%), Positives = 94/140 (67%), Gaps = 2/140 (1%)
Frame = +1
Query: 160 VLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFLALDLGG 339
+ ++T +Q+ ++ ++ +L+ GL + H ATV+ TY+ LP+G E+GKFLALDLGG
Sbjct: 476 LFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGG 535
Query: 340 TNFRVLIINL--GENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERL 513
TNFRVL++ + G M +KI+AIP IM GTG LFDHI +C+A+F+ G+ L
Sbjct: 536 TNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASL 595
Query: 514 ALGFTFSFPLKQLGLTKGVL 573
LGFTFSFP +Q+ + KG L
Sbjct: 596 PLGFTFSFPCRQMSIDKGTL 615
Score = 124 bits (298), Expect = 4e-28
Identities = 58/152 (38%), Positives = 98/152 (64%), Gaps = 3/152 (1%)
Frame = +1
Query: 127 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKE 306
D ++++ ++++D + +IM R +++KGL++ + A VK T+++ +P+G E
Sbjct: 17 DQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSE 76
Query: 307 RGKFLALDLGGTNFRVLIINL---GENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLAN 477
G+FL+LDLGG+ FRVL + + G+ H M+S+ Y P I+ G G LF+++A+CLA+
Sbjct: 77 NGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLAD 136
Query: 478 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVL 573
FMK + ++L LG TFSFP +Q L +GVL
Sbjct: 137 FMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVL 168
>BC012337-1|AAH12337.1| 677|Homo sapiens HKDC1 protein protein.
Length = 677
Score = 137 bits (332), Expect = 3e-32
Identities = 65/140 (46%), Positives = 94/140 (67%), Gaps = 2/140 (1%)
Frame = +1
Query: 160 VLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFLALDLGG 339
+ ++T +Q+ ++ ++ +L+ GL + H ATV+ TY+ LP+G E+GKFLALDLGG
Sbjct: 236 LFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGG 295
Query: 340 TNFRVLIINL--GENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERL 513
TNFRVL++ + G M +KI+AIP IM GTG LFDHI +C+A+F+ G+ L
Sbjct: 296 TNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASL 355
Query: 514 ALGFTFSFPLKQLGLTKGVL 573
LGFTFSFP +Q+ + KG L
Sbjct: 356 PLGFTFSFPCRQMSIDKGTL 375
>AL596223-3|CAH71500.1| 917|Homo sapiens hexokinase domain
containing 1 protein.
Length = 917
Score = 137 bits (332), Expect = 3e-32
Identities = 65/140 (46%), Positives = 94/140 (67%), Gaps = 2/140 (1%)
Frame = +1
Query: 160 VLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFLALDLGG 339
+ ++T +Q+ ++ ++ +L+ GL + H ATV+ TY+ LP+G E+GKFLALDLGG
Sbjct: 476 LFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGG 535
Query: 340 TNFRVLIINL--GENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERL 513
TNFRVL++ + G M +KI+AIP IM GTG LFDHI +C+A+F+ G+ L
Sbjct: 536 TNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASL 595
Query: 514 ALGFTFSFPLKQLGLTKGVL 573
LGFTFSFP +Q+ + KG L
Sbjct: 596 PLGFTFSFPCRQMSIDKGTL 615
Score = 124 bits (298), Expect = 4e-28
Identities = 58/152 (38%), Positives = 98/152 (64%), Gaps = 3/152 (1%)
Frame = +1
Query: 127 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKE 306
D ++++ ++++D + +IM R +++KGL++ + A VK T+++ +P+G E
Sbjct: 17 DQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSE 76
Query: 307 RGKFLALDLGGTNFRVLIINL---GENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLAN 477
G+FL+LDLGG+ FRVL + + G+ H M+S+ Y P I+ G G LF+++A+CLA+
Sbjct: 77 NGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLAD 136
Query: 478 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVL 573
FMK + ++L LG TFSFP +Q L +GVL
Sbjct: 137 FMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVL 168
>AK026414-1|BAB15478.1| 325|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22761 fis, clone KAIA0893. ).
Length = 325
Score = 137 bits (332), Expect = 3e-32
Identities = 65/140 (46%), Positives = 94/140 (67%), Gaps = 2/140 (1%)
Frame = +1
Query: 160 VLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFLALDLGG 339
+ ++T +Q+ ++ ++ +L+ GL + H ATV+ TY+ LP+G E+GKFLALDLGG
Sbjct: 65 LFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGG 124
Query: 340 TNFRVLIINL--GENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERL 513
TNFRVL++ + G M +KI+AIP IM GTG LFDHI +C+A+F+ G+ L
Sbjct: 125 TNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASL 184
Query: 514 ALGFTFSFPLKQLGLTKGVL 573
LGFTFSFP +Q+ + KG L
Sbjct: 185 PLGFTFSFPCRQMSIDKGTL 204
>AC104135-1|AAY24209.1| 573|Homo sapiens unknown protein.
Length = 573
Score = 132 bits (320), Expect = 8e-31
Identities = 68/164 (41%), Positives = 103/164 (62%), Gaps = 3/164 (1%)
Frame = +1
Query: 121 VVDNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNG 300
+ D + ++ E L+++ Q+ E+ R+ ++++GLS+ H A VK TY+ P+G
Sbjct: 119 LADQHRARQKTLEHLQLSHDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDG 178
Query: 301 KERGKFLALDLGGTNFRVLIINLGENHF---DMQSKIYAIPKHIMTGTGIALFDHIAECL 471
E+G FLALDLGGTNFRVL++ + + +M +KIYAIP+ +M GTG LFDHI +C+
Sbjct: 179 TEKGDFLALDLGGTNFRVLLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCI 238
Query: 472 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
A+F++ G+ L LGFTFSFP +Q L + +L K F S
Sbjct: 239 ADFLEYMGMKGVSLPLGFTFSFPCQQNSLDESILLKWTKGFKAS 282
>M75126-1|AAA52646.1| 917|Homo sapiens hexokinase 1 protein.
Length = 917
Score = 130 bits (315), Expect = 3e-30
Identities = 60/162 (37%), Positives = 107/162 (66%), Gaps = 3/162 (1%)
Frame = +1
Query: 127 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKE 306
D +++I + ++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E
Sbjct: 17 DQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSE 76
Query: 307 RGKFLALDLGGTNFRVLIINLGEN---HFDMQSKIYAIPKHIMTGTGIALFDHIAECLAN 477
+G F+ALDLGG++FR+L + + + M+S++Y P++I+ G+G LFDH+AECL +
Sbjct: 77 KGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGD 136
Query: 478 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
FM++ + +++L +GFTFSFP +Q + + +L RF S
Sbjct: 137 FMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKAS 178
Score = 125 bits (301), Expect = 2e-28
Identities = 63/149 (42%), Positives = 92/149 (61%), Gaps = 3/149 (2%)
Frame = +1
Query: 136 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGK 315
++I E +T + E+ R+ +++ GL + H A VK ++++ P+G E G
Sbjct: 468 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 527
Query: 316 FLALDLGGTNFRVLIINL--GENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMK 486
FLALDLGGTNFRVL++ + G+ +M +KIYAIP IM GTG LFDHI C+++F+
Sbjct: 528 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 587
Query: 487 EHGVYEERLALGFTFSFPLKQLGLTKGVL 573
G+ R+ LGFTFSFP +Q L G+L
Sbjct: 588 YMGIKGPRMPLGFTFSFPCQQTSLDAGIL 616
>BC008730-1|AAH08730.1| 917|Homo sapiens hexokinase 1 protein.
Length = 917
Score = 130 bits (315), Expect = 3e-30
Identities = 60/162 (37%), Positives = 107/162 (66%), Gaps = 3/162 (1%)
Frame = +1
Query: 127 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKE 306
D +++I + ++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E
Sbjct: 17 DQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSE 76
Query: 307 RGKFLALDLGGTNFRVLIINLGEN---HFDMQSKIYAIPKHIMTGTGIALFDHIAECLAN 477
+G F+ALDLGG++FR+L + + + M+S++Y P++I+ G+G LFDH+AECL +
Sbjct: 77 KGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGD 136
Query: 478 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
FM++ + +++L +GFTFSFP +Q + + +L RF S
Sbjct: 137 FMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKAS 178
Score = 125 bits (301), Expect = 2e-28
Identities = 63/149 (42%), Positives = 92/149 (61%), Gaps = 3/149 (2%)
Frame = +1
Query: 136 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGK 315
++I E +T + E+ R+ +++ GL + H A VK ++++ P+G E G
Sbjct: 468 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 527
Query: 316 FLALDLGGTNFRVLIINL--GENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMK 486
FLALDLGGTNFRVL++ + G+ +M +KIYAIP IM GTG LFDHI C+++F+
Sbjct: 528 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 587
Query: 487 EHGVYEERLALGFTFSFPLKQLGLTKGVL 573
G+ R+ LGFTFSFP +Q L G+L
Sbjct: 588 YMGIKGPRMPLGFTFSFPCQQTSLDAGIL 616
>AL596223-9|CAH71506.1| 917|Homo sapiens hexokinase 1 protein.
Length = 917
Score = 130 bits (315), Expect = 3e-30
Identities = 60/162 (37%), Positives = 107/162 (66%), Gaps = 3/162 (1%)
Frame = +1
Query: 127 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKE 306
D +++I + ++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E
Sbjct: 17 DQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSE 76
Query: 307 RGKFLALDLGGTNFRVLIINLGEN---HFDMQSKIYAIPKHIMTGTGIALFDHIAECLAN 477
+G F+ALDLGG++FR+L + + + M+S++Y P++I+ G+G LFDH+AECL +
Sbjct: 77 KGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGD 136
Query: 478 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
FM++ + +++L +GFTFSFP +Q + + +L RF S
Sbjct: 137 FMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKAS 178
Score = 125 bits (301), Expect = 2e-28
Identities = 63/149 (42%), Positives = 92/149 (61%), Gaps = 3/149 (2%)
Frame = +1
Query: 136 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGK 315
++I E +T + E+ R+ +++ GL + H A VK ++++ P+G E G
Sbjct: 468 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 527
Query: 316 FLALDLGGTNFRVLIINL--GENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMK 486
FLALDLGGTNFRVL++ + G+ +M +KIYAIP IM GTG LFDHI C+++F+
Sbjct: 528 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 587
Query: 487 EHGVYEERLALGFTFSFPLKQLGLTKGVL 573
G+ R+ LGFTFSFP +Q L G+L
Sbjct: 588 YMGIKGPRMPLGFTFSFPCQQTSLDAGIL 616
>AF016365-4|AAC15862.1| 917|Homo sapiens hexokinase I protein.
Length = 917
Score = 130 bits (315), Expect = 3e-30
Identities = 60/162 (37%), Positives = 107/162 (66%), Gaps = 3/162 (1%)
Frame = +1
Query: 127 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKE 306
D +++I + ++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E
Sbjct: 17 DQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSE 76
Query: 307 RGKFLALDLGGTNFRVLIINLGEN---HFDMQSKIYAIPKHIMTGTGIALFDHIAECLAN 477
+G F+ALDLGG++FR+L + + + M+S++Y P++I+ G+G LFDH+AECL +
Sbjct: 77 KGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGD 136
Query: 478 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
FM++ + +++L +GFTFSFP +Q + + +L RF S
Sbjct: 137 FMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKAS 178
Score = 125 bits (301), Expect = 2e-28
Identities = 63/149 (42%), Positives = 92/149 (61%), Gaps = 3/149 (2%)
Frame = +1
Query: 136 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGK 315
++I E +T + E+ R+ +++ GL + H A VK ++++ P+G E G
Sbjct: 468 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 527
Query: 316 FLALDLGGTNFRVLIINL--GENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMK 486
FLALDLGGTNFRVL++ + G+ +M +KIYAIP IM GTG LFDHI C+++F+
Sbjct: 528 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 587
Query: 487 EHGVYEERLALGFTFSFPLKQLGLTKGVL 573
G+ R+ LGFTFSFP +Q L G+L
Sbjct: 588 YMGIKGPRMPLGFTFSFPCQQTSLDAGIL 616
>AB209526-1|BAD92763.1| 949|Homo sapiens hexokinase 1 isoform HKI
variant protein.
Length = 949
Score = 130 bits (315), Expect = 3e-30
Identities = 60/162 (37%), Positives = 107/162 (66%), Gaps = 3/162 (1%)
Frame = +1
Query: 127 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKE 306
D +++I + ++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E
Sbjct: 49 DQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSE 108
Query: 307 RGKFLALDLGGTNFRVLIINLGEN---HFDMQSKIYAIPKHIMTGTGIALFDHIAECLAN 477
+G F+ALDLGG++FR+L + + + M+S++Y P++I+ G+G LFDH+AECL +
Sbjct: 109 KGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGD 168
Query: 478 FMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
FM++ + +++L +GFTFSFP +Q + + +L RF S
Sbjct: 169 FMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKAS 210
Score = 125 bits (301), Expect = 2e-28
Identities = 63/149 (42%), Positives = 92/149 (61%), Gaps = 3/149 (2%)
Frame = +1
Query: 136 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGK 315
++I E +T + E+ R+ +++ GL + H A VK ++++ P+G E G
Sbjct: 500 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 559
Query: 316 FLALDLGGTNFRVLIINL--GENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMK 486
FLALDLGGTNFRVL++ + G+ +M +KIYAIP IM GTG LFDHI C+++F+
Sbjct: 560 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 619
Query: 487 EHGVYEERLALGFTFSFPLKQLGLTKGVL 573
G+ R+ LGFTFSFP +Q L G+L
Sbjct: 620 YMGIKGPRMPLGFTFSFPCQQTSLDAGIL 648
>BC021278-1|AAH21278.1| 427|Homo sapiens HKDC1 protein protein.
Length = 427
Score = 129 bits (312), Expect = 7e-30
Identities = 63/122 (51%), Positives = 83/122 (68%), Gaps = 2/122 (1%)
Frame = +1
Query: 214 DLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFLALDLGGTNFRVLIINL--GENHFD 387
+L+ GL + H ATV+ TY+ LP+G E+GKFLALDLGGTNFRVL++ + G
Sbjct: 4 ELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLVKIRSGRRSVR 63
Query: 388 MQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKG 567
M +KI+AIP IM GTG LFDHI +C+A+F+ G+ L LGFTFSFP +Q+ + KG
Sbjct: 64 MYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKG 123
Query: 568 VL 573
L
Sbjct: 124 TL 125
>AL596223-8|CAH71505.1| 291|Homo sapiens hexokinase 1 protein.
Length = 291
Score = 127 bits (307), Expect = 3e-29
Identities = 58/150 (38%), Positives = 101/150 (67%), Gaps = 3/150 (2%)
Frame = +1
Query: 163 LKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFLALDLGGT 342
++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E+G F+ALDLGG+
Sbjct: 28 MRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGS 87
Query: 343 NFRVLIINLGEN---HFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERL 513
+FR+L + + + M+S++Y P++I+ G+G LFDH+AECL +FM++ + +++L
Sbjct: 88 SFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKL 147
Query: 514 ALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
+GFTFSFP +Q + + +L RF S
Sbjct: 148 PVGFTFSFPCQQSKIDEAILITWTKRFKAS 177
>AF016365-3|AAC15863.1| 916|Homo sapiens hexokinase IR protein.
Length = 916
Score = 127 bits (307), Expect = 3e-29
Identities = 58/150 (38%), Positives = 101/150 (67%), Gaps = 3/150 (2%)
Frame = +1
Query: 163 LKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFLALDLGGT 342
++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E+G F+ALDLGG+
Sbjct: 28 MRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGS 87
Query: 343 NFRVLIINLGEN---HFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERL 513
+FR+L + + + M+S++Y P++I+ G+G LFDH+AECL +FM++ + +++L
Sbjct: 88 SFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKL 147
Query: 514 ALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
+GFTFSFP +Q + + +L RF S
Sbjct: 148 PVGFTFSFPCQQSKIDEAILITWTKRFKAS 177
Score = 125 bits (301), Expect = 2e-28
Identities = 63/149 (42%), Positives = 92/149 (61%), Gaps = 3/149 (2%)
Frame = +1
Query: 136 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGK 315
++I E +T + E+ R+ +++ GL + H A VK ++++ P+G E G
Sbjct: 467 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 526
Query: 316 FLALDLGGTNFRVLIINL--GENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMK 486
FLALDLGGTNFRVL++ + G+ +M +KIYAIP IM GTG LFDHI C+++F+
Sbjct: 527 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 586
Query: 487 EHGVYEERLALGFTFSFPLKQLGLTKGVL 573
G+ R+ LGFTFSFP +Q L G+L
Sbjct: 587 YMGIKGPRMPLGFTFSFPCQQTSLDAGIL 615
>AF016365-2|AAF82320.1| 905|Homo sapiens hexokinase 1 isoform td
protein.
Length = 905
Score = 127 bits (307), Expect = 3e-29
Identities = 58/150 (38%), Positives = 101/150 (67%), Gaps = 3/150 (2%)
Frame = +1
Query: 163 LKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFLALDLGGT 342
++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E+G F+ALDLGG+
Sbjct: 17 MRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGS 76
Query: 343 NFRVLIINLGEN---HFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERL 513
+FR+L + + + M+S++Y P++I+ G+G LFDH+AECL +FM++ + +++L
Sbjct: 77 SFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKL 136
Query: 514 ALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
+GFTFSFP +Q + + +L RF S
Sbjct: 137 PVGFTFSFPCQQSKIDEAILITWTKRFKAS 166
Score = 125 bits (301), Expect = 2e-28
Identities = 63/149 (42%), Positives = 92/149 (61%), Gaps = 3/149 (2%)
Frame = +1
Query: 136 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGK 315
++I E +T + E+ R+ +++ GL + H A VK ++++ P+G E G
Sbjct: 456 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 515
Query: 316 FLALDLGGTNFRVLIINL--GENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMK 486
FLALDLGGTNFRVL++ + G+ +M +KIYAIP IM GTG LFDHI C+++F+
Sbjct: 516 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 575
Query: 487 EHGVYEERLALGFTFSFPLKQLGLTKGVL 573
G+ R+ LGFTFSFP +Q L G+L
Sbjct: 576 YMGIKGPRMPLGFTFSFPCQQTSLDAGIL 604
>AF016365-1|AAF82319.1| 921|Homo sapiens hexokinase 1 isoform ta/tb
protein.
Length = 921
Score = 127 bits (307), Expect = 3e-29
Identities = 58/150 (38%), Positives = 101/150 (67%), Gaps = 3/150 (2%)
Frame = +1
Query: 163 LKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFLALDLGGT 342
++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E+G F+ALDLGG+
Sbjct: 33 MRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGS 92
Query: 343 NFRVLIINLGEN---HFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEERL 513
+FR+L + + + M+S++Y P++I+ G+G LFDH+AECL +FM++ + +++L
Sbjct: 93 SFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKL 152
Query: 514 ALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
+GFTFSFP +Q + + +L RF S
Sbjct: 153 PVGFTFSFPCQQSKIDEAILITWTKRFKAS 182
Score = 125 bits (301), Expect = 2e-28
Identities = 63/149 (42%), Positives = 92/149 (61%), Gaps = 3/149 (2%)
Frame = +1
Query: 136 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGK 315
++I E +T + E+ R+ +++ GL + H A VK ++++ P+G E G
Sbjct: 472 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 531
Query: 316 FLALDLGGTNFRVLIINL--GENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMK 486
FLALDLGGTNFRVL++ + G+ +M +KIYAIP IM GTG LFDHI C+++F+
Sbjct: 532 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 591
Query: 487 EHGVYEERLALGFTFSFPLKQLGLTKGVL 573
G+ R+ LGFTFSFP +Q L G+L
Sbjct: 592 YMGIKGPRMPLGFTFSFPCQQTSLDAGIL 620
>M90299-1|AAA52562.1| 465|Homo sapiens glucokinase protein.
Length = 465
Score = 126 bits (304), Expect = 7e-29
Identities = 57/151 (37%), Positives = 101/151 (66%), Gaps = 5/151 (3%)
Frame = +1
Query: 136 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGK 315
+++ + ++ ++ +K++M R+ ++ +GL H A+VK TY++ P G E G
Sbjct: 14 EKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGD 73
Query: 316 FLALDLGGTNFRVLIINLG---ENHFDMQSK--IYAIPKHIMTGTGIALFDHIAECLANF 480
FL+LDLGGTNFRV+++ +G E + +++K +Y+IP+ MTGT LFD+I+EC+++F
Sbjct: 74 FLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDF 133
Query: 481 MKEHGVYEERLALGFTFSFPLKQLGLTKGVL 573
+ +H + ++L LGFTFSFP++ + KG+L
Sbjct: 134 LDKHQMKHKKLPLGFTFSFPVRHEDIDKGIL 164
>M88011-1|AAA51824.1| 465|Homo sapiens glucokinase protein.
Length = 465
Score = 126 bits (304), Expect = 7e-29
Identities = 57/151 (37%), Positives = 101/151 (66%), Gaps = 5/151 (3%)
Frame = +1
Query: 136 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGK 315
+++ + ++ ++ +K++M R+ ++ +GL H A+VK TY++ P G E G
Sbjct: 14 EKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGD 73
Query: 316 FLALDLGGTNFRVLIINLG---ENHFDMQSK--IYAIPKHIMTGTGIALFDHIAECLANF 480
FL+LDLGGTNFRV+++ +G E + +++K +Y+IP+ MTGT LFD+I+EC+++F
Sbjct: 74 FLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDF 133
Query: 481 MKEHGVYEERLALGFTFSFPLKQLGLTKGVL 573
+ +H + ++L LGFTFSFP++ + KG+L
Sbjct: 134 LDKHQMKHKKLPLGFTFSFPVRHEDIDKGIL 164
>EU008605-1|ABS31137.1| 465|Homo sapiens glucokinase protein.
Length = 465
Score = 126 bits (304), Expect = 7e-29
Identities = 57/151 (37%), Positives = 101/151 (66%), Gaps = 5/151 (3%)
Frame = +1
Query: 136 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGK 315
+++ + ++ ++ +K++M R+ ++ +GL H A+VK TY++ P G E G
Sbjct: 14 EKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGD 73
Query: 316 FLALDLGGTNFRVLIINLG---ENHFDMQSK--IYAIPKHIMTGTGIALFDHIAECLANF 480
FL+LDLGGTNFRV+++ +G E + +++K +Y+IP+ MTGT LFD+I+EC+++F
Sbjct: 74 FLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDF 133
Query: 481 MKEHGVYEERLALGFTFSFPLKQLGLTKGVL 573
+ +H + ++L LGFTFSFP++ + KG+L
Sbjct: 134 LDKHQMKHKKLPLGFTFSFPVRHEDIDKGIL 164
>BT007062-1|AAP35711.1| 465|Homo sapiens glucokinase (hexokinase 4,
maturity onset diabetes of the young 2) protein.
Length = 465
Score = 126 bits (304), Expect = 7e-29
Identities = 57/151 (37%), Positives = 101/151 (66%), Gaps = 5/151 (3%)
Frame = +1
Query: 136 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGK 315
+++ + ++ ++ +K++M R+ ++ +GL H A+VK TY++ P G E G
Sbjct: 14 EKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGD 73
Query: 316 FLALDLGGTNFRVLIINLG---ENHFDMQSK--IYAIPKHIMTGTGIALFDHIAECLANF 480
FL+LDLGGTNFRV+++ +G E + +++K +Y+IP+ MTGT LFD+I+EC+++F
Sbjct: 74 FLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDF 133
Query: 481 MKEHGVYEERLALGFTFSFPLKQLGLTKGVL 573
+ +H + ++L LGFTFSFP++ + KG+L
Sbjct: 134 LDKHQMKHKKLPLGFTFSFPVRHEDIDKGIL 164
>BC001890-1|AAH01890.1| 465|Homo sapiens glucokinase (hexokinase 4,
maturity onset diabetes of the young 2) protein.
Length = 465
Score = 126 bits (304), Expect = 7e-29
Identities = 57/151 (37%), Positives = 101/151 (66%), Gaps = 5/151 (3%)
Frame = +1
Query: 136 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGK 315
+++ + ++ ++ +K++M R+ ++ +GL H A+VK TY++ P G E G
Sbjct: 14 EKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGD 73
Query: 316 FLALDLGGTNFRVLIINLG---ENHFDMQSK--IYAIPKHIMTGTGIALFDHIAECLANF 480
FL+LDLGGTNFRV+++ +G E + +++K +Y+IP+ MTGT LFD+I+EC+++F
Sbjct: 74 FLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDF 133
Query: 481 MKEHGVYEERLALGFTFSFPLKQLGLTKGVL 573
+ +H + ++L LGFTFSFP++ + KG+L
Sbjct: 134 LDKHQMKHKKLPLGFTFSFPVRHEDIDKGIL 164
>AF041022-1|AAB97680.1| 465|Homo sapiens glucokinase protein.
Length = 465
Score = 126 bits (304), Expect = 7e-29
Identities = 57/151 (37%), Positives = 101/151 (66%), Gaps = 5/151 (3%)
Frame = +1
Query: 136 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGK 315
+++ + ++ ++ +K++M R+ ++ +GL H A+VK TY++ P G E G
Sbjct: 14 EKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGD 73
Query: 316 FLALDLGGTNFRVLIINLG---ENHFDMQSK--IYAIPKHIMTGTGIALFDHIAECLANF 480
FL+LDLGGTNFRV+++ +G E + +++K +Y+IP+ MTGT LFD+I+EC+++F
Sbjct: 74 FLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDF 133
Query: 481 MKEHGVYEERLALGFTFSFPLKQLGLTKGVL 573
+ +H + ++L LGFTFSFP++ + KG+L
Sbjct: 134 LDKHQMKHKKLPLGFTFSFPVRHEDIDKGIL 164
>AF041022-3|AAB97682.1| 464|Homo sapiens glucokinase protein.
Length = 464
Score = 125 bits (302), Expect = 1e-28
Identities = 57/141 (40%), Positives = 97/141 (68%), Gaps = 5/141 (3%)
Frame = +1
Query: 166 KMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFLALDLGGTN 345
++ ++ +K++M R+ ++ +GL H A+VK TY++ P G E G FL+LDLGGTN
Sbjct: 23 QLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTN 82
Query: 346 FRVLIINLG---ENHFDMQSK--IYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEER 510
FRV+++ +G E + +++K +Y+IP+ MTGT LFD+I+EC+++F+ +H + ++
Sbjct: 83 FRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKK 142
Query: 511 LALGFTFSFPLKQLGLTKGVL 573
L LGFTFSFP++ + KG+L
Sbjct: 143 LPLGFTFSFPVRHEDIDKGIL 163
>AF041022-2|AAB97681.1| 466|Homo sapiens glucokinase protein.
Length = 466
Score = 125 bits (302), Expect = 1e-28
Identities = 57/141 (40%), Positives = 97/141 (68%), Gaps = 5/141 (3%)
Frame = +1
Query: 166 KMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFLALDLGGTN 345
++ ++ +K++M R+ ++ +GL H A+VK TY++ P G E G FL+LDLGGTN
Sbjct: 25 QLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTN 84
Query: 346 FRVLIINLG---ENHFDMQSK--IYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEER 510
FRV+++ +G E + +++K +Y+IP+ MTGT LFD+I+EC+++F+ +H + ++
Sbjct: 85 FRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKK 144
Query: 511 LALGFTFSFPLKQLGLTKGVL 573
L LGFTFSFP++ + KG+L
Sbjct: 145 LPLGFTFSFPVRHEDIDKGIL 165
>X66957-1|CAA47379.1| 631|Homo sapiens hexokinase type 1 protein.
Length = 631
Score = 125 bits (301), Expect = 2e-28
Identities = 63/149 (42%), Positives = 92/149 (61%), Gaps = 3/149 (2%)
Frame = +1
Query: 136 QRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGK 315
++I E +T + E+ R+ +++ GL + H A VK ++++ P+G E G
Sbjct: 182 RQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGD 241
Query: 316 FLALDLGGTNFRVLIINL--GENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMK 486
FLALDLGGTNFRVL++ + G+ +M +KIYAIP IM GTG LFDHI C+++F+
Sbjct: 242 FLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLD 301
Query: 487 EHGVYEERLALGFTFSFPLKQLGLTKGVL 573
G+ R+ LGFTFSFP +Q L G+L
Sbjct: 302 YMGIKGPRMPLGFTFSFPCQQTSLDAGIL 330
>M69051-1|AAB59563.1| 464|Homo sapiens glucokinase protein.
Length = 464
Score = 124 bits (300), Expect = 2e-28
Identities = 57/141 (40%), Positives = 96/141 (68%), Gaps = 5/141 (3%)
Frame = +1
Query: 166 KMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFLALDLGGTN 345
++ ++ +K++M R+ ++ +GL H A+VK TY++ P G E G FL+LDLGGTN
Sbjct: 23 QLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTN 82
Query: 346 FRVLIINLG---ENHFDMQSK--IYAIPKHIMTGTGIALFDHIAECLANFMKEHGVYEER 510
FRV+++ +G E + +++K Y+IP+ MTGT LFD+I+EC+++F+ +H + ++
Sbjct: 83 FRVMLVKVGEGEEGQWSVKTKHQTYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKK 142
Query: 511 LALGFTFSFPLKQLGLTKGVL 573
L LGFTFSFP++ + KG+L
Sbjct: 143 LPLGFTFSFPVRHEDIDKGIL 163
>U51333-1|AAC50732.1| 923|Homo sapiens hexokinase III protein.
Length = 923
Score = 116 bits (279), Expect = 7e-26
Identities = 56/144 (38%), Positives = 92/144 (63%)
Frame = +1
Query: 142 IREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFL 321
+ E ++ Q+ + ++ + KGL R + ++++ T+++ P+G ERG FL
Sbjct: 483 LEETLAPFRLNHDQLAAVQAQMRKAMAKGL-RGEA--SSLRMLPTFVRATPDGSERGDFL 539
Query: 322 ALDLGGTNFRVLIINLGENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVY 501
ALDLGGTNFRVL++ + + S+IY+IP+ + G+G LFDHI +C+ +F ++ G+
Sbjct: 540 ALDLGGTNFRVLLVRVTTG-VQITSEIYSIPETVAQGSGQQLFDHIVDCIVDFQQKQGLS 598
Query: 502 EERLALGFTFSFPLKQLGLTKGVL 573
+ L LGFTFSFP +QLGL +G+L
Sbjct: 599 GQSLPLGFTFSFPCRQLGLDQGIL 622
Score = 92.7 bits (220), Expect = 1e-18
Identities = 55/164 (33%), Positives = 87/164 (53%), Gaps = 5/164 (3%)
Frame = +1
Query: 127 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKE 306
D+ + ++E + K+T Q+++I L +++ L V+ TY+ P+G E
Sbjct: 28 DSSELVQECLQQFKVTRAQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGSTPHGTE 87
Query: 307 RGKFLALDLG--GTNFRVLIINLG--ENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECL 471
+G F+ L+LG G + RVL + L E H + +S+ + IP+ +M G G LFD A CL
Sbjct: 88 QGDFVVLELGATGASLRVLWVTLTGIEGHRVEPRSQEFVIPQEVMLGAGQQLFDFAAHCL 147
Query: 472 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
+ F+ V ++ L LGF+FSFP Q GL + L F CS
Sbjct: 148 SEFLDAQPVNKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCS 191
>BC028129-1|AAH28129.1| 923|Homo sapiens hexokinase 3 (white cell)
protein.
Length = 923
Score = 116 bits (279), Expect = 7e-26
Identities = 56/144 (38%), Positives = 92/144 (63%)
Frame = +1
Query: 142 IREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFL 321
+ E ++ Q+ + ++ + KGL R + ++++ T+++ P+G ERG FL
Sbjct: 483 LEETLAPFRLNHDQLAAVQAQMRKAMAKGL-RGEA--SSLRMLPTFVRATPDGSERGDFL 539
Query: 322 ALDLGGTNFRVLIINLGENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVY 501
ALDLGGTNFRVL++ + + S+IY+IP+ + G+G LFDHI +C+ +F ++ G+
Sbjct: 540 ALDLGGTNFRVLLVRVTTG-VQITSEIYSIPETVAQGSGQQLFDHIVDCIVDFQQKQGLS 598
Query: 502 EERLALGFTFSFPLKQLGLTKGVL 573
+ L LGFTFSFP +QLGL +G+L
Sbjct: 599 GQSLPLGFTFSFPCRQLGLDQGIL 622
Score = 92.7 bits (220), Expect = 1e-18
Identities = 55/164 (33%), Positives = 87/164 (53%), Gaps = 5/164 (3%)
Frame = +1
Query: 127 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKE 306
D+ + ++E + K+T Q+++I L +++ L V+ TY+ P+G E
Sbjct: 28 DSSELVQECLQQFKVTRAQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGSTPHGTE 87
Query: 307 RGKFLALDLG--GTNFRVLIINLG--ENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECL 471
+G F+ L+LG G + RVL + L E H + +S+ + IP+ +M G G LFD A CL
Sbjct: 88 QGDFVVLELGATGASLRVLWVTLTGIEGHRVEPRSQEFVIPQEVMLGAGQQLFDFAAHCL 147
Query: 472 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
+ F+ V ++ L LGF+FSFP Q GL + L F CS
Sbjct: 148 SEFLDAQPVNKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCS 191
>AB208951-1|BAD92188.1| 960|Homo sapiens Hexokinase 3 variant
protein.
Length = 960
Score = 116 bits (279), Expect = 7e-26
Identities = 56/144 (38%), Positives = 92/144 (63%)
Frame = +1
Query: 142 IREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFL 321
+ E ++ Q+ + ++ + KGL R + ++++ T+++ P+G ERG FL
Sbjct: 453 LEETLAPFRLNHDQLAAVQAQMRKAMAKGL-RGEA--SSLRMLPTFVRATPDGSERGDFL 509
Query: 322 ALDLGGTNFRVLIINLGENHFDMQSKIYAIPKHIMTGTGIALFDHIAECLANFMKEHGVY 501
ALDLGGTNFRVL++ + + S+IY+IP+ + G+G LFDHI +C+ +F ++ G+
Sbjct: 510 ALDLGGTNFRVLLVRVTTG-VQITSEIYSIPETVAQGSGQQLFDHIVDCIVDFQQKQGLS 568
Query: 502 EERLALGFTFSFPLKQLGLTKGVL 573
+ L LGFTFSFP +QLGL +G+L
Sbjct: 569 GQSLPLGFTFSFPCRQLGLDQGIL 592
Score = 92.7 bits (220), Expect = 1e-18
Identities = 55/164 (33%), Positives = 87/164 (53%), Gaps = 5/164 (3%)
Frame = +1
Query: 127 DNLQRIREECEVLKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKE 306
D+ + ++E + K+T Q+++I L +++ L V+ TY+ P+G E
Sbjct: 40 DSSELVQECLQQFKVTRAQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGSTPHGTE 99
Query: 307 RGKFLALDLG--GTNFRVLIINLG--ENH-FDMQSKIYAIPKHIMTGTGIALFDHIAECL 471
+G F+ L+LG G + RVL + L E H + +S+ + IP+ +M G G LFD A CL
Sbjct: 100 QGDFVVLELGATGASLRVLWVTLTGIEGHRVEPRSQEFVIPQEVMLGAGQQLFDFAAHCL 159
Query: 472 ANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVLQKMD*RFSCS 603
+ F+ V ++ L LGF+FSFP Q GL + L F CS
Sbjct: 160 SEFLDAQPVNKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCS 203
>U42303-1|AAC50422.1| 566|Homo sapiens ATP:D-hexose
6-phosphotransferase protein.
Length = 566
Score = 103 bits (248), Expect = 4e-22
Identities = 47/100 (47%), Positives = 69/100 (69%)
Frame = +1
Query: 274 TYIQDLPNGKERGKFLALDLGGTNFRVLIINLGENHFDMQSKIYAIPKHIMTGTGIALFD 453
T+++ G ERG FLALDLGGTNFRVL++ + + S+IY+IP+ + G+ LFD
Sbjct: 167 TFVRATLTGSERGDFLALDLGGTNFRVLLVRVTTG-VQITSEIYSIPETVAQGSAEQLFD 225
Query: 454 HIAECLANFMKEHGVYEERLALGFTFSFPLKQLGLTKGVL 573
HI +C+ +F ++ G+ + L GFTFSFP +QLGL +G+L
Sbjct: 226 HIVDCIVDFQQKQGLSGQSLPTGFTFSFPCRQLGLDQGIL 265
>AL596223-5|CAH71502.1| 139|Homo sapiens hexokinase 1 protein.
Length = 139
Score = 96.7 bits (230), Expect = 6e-20
Identities = 43/106 (40%), Positives = 74/106 (69%), Gaps = 3/106 (2%)
Frame = +1
Query: 163 LKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFLALDLGGT 342
++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E+G F+ALDLGG+
Sbjct: 33 MRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGS 92
Query: 343 NFRVLIINLG---ENHFDMQSKIYAIPKHIMTGTGIALFDHIAECL 471
+FR+L + + + M+S++Y P++I+ G+G LFDH+AECL
Sbjct: 93 SFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECL 138
>AL596223-7|CAH71504.1| 114|Homo sapiens hexokinase 1 protein.
Length = 114
Score = 78.6 bits (185), Expect = 2e-14
Identities = 36/98 (36%), Positives = 66/98 (67%), Gaps = 3/98 (3%)
Frame = +1
Query: 163 LKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFLALDLGGT 342
++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E+G F+ALDLGG+
Sbjct: 17 MRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGS 76
Query: 343 NFRVLIINLG---ENHFDMQSKIYAIPKHIMTGTGIAL 447
+FR+L + + + M+S++Y P++I+ G+G L
Sbjct: 77 SFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQL 114
>AF073786-1|AAC25424.1| 114|Homo sapiens testis-specific hexokinase
1 protein.
Length = 114
Score = 78.6 bits (185), Expect = 2e-14
Identities = 36/98 (36%), Positives = 66/98 (67%), Gaps = 3/98 (3%)
Frame = +1
Query: 163 LKMTDKQIKEIMCRLHNDLKKGLSRADHX*ATVKCWITYIQDLPNGKERGKFLALDLGGT 342
++++D+ + +IM R ++K GLSR + ATVK T+++ +P+G E+G F+ALDLGG+
Sbjct: 17 MRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGS 76
Query: 343 NFRVLIINLG---ENHFDMQSKIYAIPKHIMTGTGIAL 447
+FR+L + + + M+S++Y P++I+ G+G L
Sbjct: 77 SFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQL 114
>BC121179-1|AAI21180.1| 722|Homo sapiens glucosamine
(UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
protein.
Length = 722
Score = 30.3 bits (65), Expect = 6.3
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 283 QDLPNGKERGKFLALDLGGTNFRVLIINL 369
QD+ + E LA+DLGGTN RV I+++
Sbjct: 398 QDIDHILETLSALAVDLGGTNLRVAIVSM 426
>AY531128-1|AAS59259.1| 722|Homo sapiens
UDP-N-acetylglucosamine-2-epimerase /
N-acetylmannosamine kinase protein.
Length = 722
Score = 30.3 bits (65), Expect = 6.3
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 283 QDLPNGKERGKFLALDLGGTNFRVLIINL 369
QD+ + E LA+DLGGTN RV I+++
Sbjct: 398 QDIDHILETLSALAVDLGGTNLRVAIVSM 426
>AY531127-1|AAS59258.1| 722|Homo sapiens
UDP-N-acetylglucosamine-2-epimerase /
N-acetylmannosamine kinase protein.
Length = 722
Score = 30.3 bits (65), Expect = 6.3
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 283 QDLPNGKERGKFLALDLGGTNFRVLIINL 369
QD+ + E LA+DLGGTN RV I+++
Sbjct: 398 QDIDHILETLSALAVDLGGTNLRVAIVSM 426
>AY531126-1|AAS59257.1| 722|Homo sapiens
UDP-N-acetylglucosamine-2-epimerase /
N-acetylmannosamine kinase protein.
Length = 722
Score = 30.3 bits (65), Expect = 6.3
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 283 QDLPNGKERGKFLALDLGGTNFRVLIINL 369
QD+ + E LA+DLGGTN RV I+++
Sbjct: 398 QDIDHILETLSALAVDLGGTNLRVAIVSM 426
>AM697709-1|CAM91425.1| 681|Homo sapiens UDP-N-acetylglucosamine
2-epimerase/N-acetylmannosamine kinase protein.
Length = 681
Score = 30.3 bits (65), Expect = 6.3
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 283 QDLPNGKERGKFLALDLGGTNFRVLIINL 369
QD+ + E LA+DLGGTN RV I+++
Sbjct: 357 QDIDHILETLSALAVDLGGTNLRVAIVSM 385
>AM697708-1|CAM91424.1| 753|Homo sapiens UDP-N-acetylglucosamine
2-epimerase/N-acetylmannosamine kinase protein.
Length = 753
Score = 30.3 bits (65), Expect = 6.3
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 283 QDLPNGKERGKFLALDLGGTNFRVLIINL 369
QD+ + E LA+DLGGTN RV I+++
Sbjct: 429 QDIDHILETLSALAVDLGGTNLRVAIVSM 457
>AL158830-7|CAD13389.1| 722|Homo sapiens glucosamine
(UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
protein.
Length = 722
Score = 30.3 bits (65), Expect = 6.3
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 283 QDLPNGKERGKFLALDLGGTNFRVLIINL 369
QD+ + E LA+DLGGTN RV I+++
Sbjct: 398 QDIDHILETLSALAVDLGGTNLRVAIVSM 426
>AJ238764-1|CAB42607.1| 722|Homo sapiens
UDP-N-acetylglucosamine-2-epimerase /
N-acetylmannosamine kinase protein.
Length = 722
Score = 30.3 bits (65), Expect = 6.3
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 283 QDLPNGKERGKFLALDLGGTNFRVLIINL 369
QD+ + E LA+DLGGTN RV I+++
Sbjct: 398 QDIDHILETLSALAVDLGGTNLRVAIVSM 426
>AF317635-1|AAG31661.1| 722|Homo sapiens UDP-N-acetylglucosamine
2-epimerase protein.
Length = 722
Score = 30.3 bits (65), Expect = 6.3
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 283 QDLPNGKERGKFLALDLGGTNFRVLIINL 369
QD+ + E LA+DLGGTN RV I+++
Sbjct: 398 QDIDHILETLSALAVDLGGTNLRVAIVSM 426
>AF155663-1|AAD38197.1| 722|Homo sapiens
UDP-N-acetylglucosamine-2-epimerase/N- acetylmannosamine
kinase protein.
Length = 722
Score = 30.3 bits (65), Expect = 6.3
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 283 QDLPNGKERGKFLALDLGGTNFRVLIINL 369
QD+ + E LA+DLGGTN RV I+++
Sbjct: 398 QDIDHILETLSALAVDLGGTNLRVAIVSM 426
>AF051852-1|AAD32251.1| 722|Homo sapiens
UDP-N-acetylglucosamine-2-epimerase protein.
Length = 722
Score = 30.3 bits (65), Expect = 6.3
Identities = 14/29 (48%), Positives = 20/29 (68%)
Frame = +1
Query: 283 QDLPNGKERGKFLALDLGGTNFRVLIINL 369
QD+ + E LA+DLGGTN RV I+++
Sbjct: 398 QDIDHILETLSALAVDLGGTNLRVAIVSM 426
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 91,376,382
Number of Sequences: 237096
Number of extensions: 1918456
Number of successful extensions: 3231
Number of sequences better than 10.0: 51
Number of HSP's better than 10.0 without gapping: 3029
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3165
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7310122300
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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