Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fprWP13_F_P09
(653 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 81 4e-15
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 81 4e-15
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 81 4e-15
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 81 4e-15
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 81 4e-15
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 79 1e-14
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 79 1e-14
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 79 1e-14
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 79 1e-14
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 79 1e-14
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 79 1e-14
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 79 1e-14
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 79 1e-14
AM236046-1|CAJ84703.1| 229|Homo sapiens cytochrome P450 1A1 pro... 79 1e-14
AM233520-1|CAJ80723.1| 189|Homo sapiens cytochrome P450 1A1 pro... 79 1e-14
AM233519-1|CAJ80722.1| 189|Homo sapiens cytochrome P450 1A1 pro... 79 1e-14
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 79 1e-14
AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450 epoxyge... 79 1e-14
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 78 3e-14
L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxyla... 78 3e-14
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 78 3e-14
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 78 3e-14
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 78 3e-14
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 77 4e-14
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 77 4e-14
EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1 var... 77 4e-14
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 77 4e-14
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 77 4e-14
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 77 6e-14
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 77 6e-14
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 77 6e-14
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 77 6e-14
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 77 6e-14
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 77 6e-14
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 77 6e-14
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 77 6e-14
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 77 7e-14
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 77 7e-14
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 77 7e-14
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 76 1e-13
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 74 4e-13
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 74 4e-13
BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein. 74 4e-13
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 74 4e-13
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 74 5e-13
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 73 7e-13
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 73 7e-13
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 73 7e-13
L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein. 73 7e-13
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 73 7e-13
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 73 7e-13
BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein. 73 7e-13
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 73 7e-13
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 73 7e-13
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 73 7e-13
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 73 7e-13
BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein. 72 2e-12
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 71 4e-12
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 71 4e-12
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 71 4e-12
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 71 4e-12
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 71 4e-12
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 71 4e-12
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 71 4e-12
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 71 4e-12
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 71 4e-12
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 71 5e-12
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 71 5e-12
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 71 5e-12
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 71 5e-12
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 71 5e-12
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 71 5e-12
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 71 5e-12
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 71 5e-12
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 71 5e-12
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 71 5e-12
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 70 8e-12
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 69 2e-11
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 69 2e-11
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 69 2e-11
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 69 2e-11
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 69 2e-11
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 69 2e-11
S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxyla... 68 3e-11
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 68 3e-11
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 68 3e-11
M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein. 67 6e-11
BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein. 67 6e-11
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 64 5e-10
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 64 5e-10
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 64 5e-10
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 64 5e-10
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 62 1e-09
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 62 1e-09
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 62 1e-09
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 62 2e-09
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 62 2e-09
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 62 2e-09
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 62 2e-09
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 62 2e-09
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 62 2e-09
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 62 2e-09
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 62 2e-09
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 62 2e-09
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 61 3e-09
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 61 3e-09
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 61 3e-09
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 61 3e-09
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 61 3e-09
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 61 3e-09
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 61 3e-09
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 61 3e-09
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 60 5e-09
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 60 7e-09
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 60 7e-09
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 60 7e-09
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 60 7e-09
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 60 7e-09
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 60 7e-09
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 60 7e-09
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 59 2e-08
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 58 2e-08
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 58 2e-08
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 58 3e-08
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 57 6e-08
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 56 8e-08
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 54 3e-07
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 52 2e-06
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 52 2e-06
DQ359216-1|ABC95161.1| 347|Homo sapiens dioxin-inducible cytoch... 52 2e-06
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 52 2e-06
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 52 2e-06
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 52 2e-06
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 52 2e-06
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 52 2e-06
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 52 2e-06
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 52 2e-06
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 52 2e-06
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 52 2e-06
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 52 2e-06
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 52 2e-06
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 52 2e-06
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 52 2e-06
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 52 2e-06
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 52 2e-06
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 52 2e-06
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 52 2e-06
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 52 2e-06
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 52 2e-06
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 52 2e-06
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 52 2e-06
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 52 2e-06
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 52 2e-06
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 52 2e-06
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 52 2e-06
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 52 2e-06
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 49 1e-05
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 49 1e-05
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 49 1e-05
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 49 2e-05
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 49 2e-05
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 49 2e-05
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 49 2e-05
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 46 1e-04
AY513607-1|AAR90938.1| 100|Homo sapiens truncated cytochrome P4... 44 4e-04
AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 44 4e-04
DQ372705-1|ABD16216.1| 150|Homo sapiens mutant cytochrome p450 ... 42 0.001
AF171066-1|AAG43404.1| 112|Homo sapiens CYP1B1 variant protein. 40 0.006
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 38 0.041
BC012027-1|AAH12027.1| 168|Homo sapiens CYP2U1 protein protein. 35 0.22
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 32 1.6
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 31 2.7
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 31 2.7
AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 31 2.7
AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 31 2.7
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 31 3.6
BC036233-1|AAH36233.1| 946|Homo sapiens WDR66 protein protein. 31 3.6
BC028421-1|AAH28421.1| 1154|Homo sapiens WD repeat domain 66 pro... 31 3.6
EF122245-1|ABO41980.1| 54|Homo sapiens cytochrome P450 2F1 var... 31 4.7
X58908-1|CAA41711.1| 97|Homo sapiens steroid 21-monooxygenase ... 30 6.3
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 80.6 bits (190), Expect = 4e-15
Identities = 43/144 (29%), Positives = 75/144 (52%), Gaps = 2/144 (1%)
Frame = +1
Query: 220 FKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSD 399
F K + +N PPGPW LP +G +D H+ + K YG ++ L++G I AV+++
Sbjct: 34 FLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITG 93
Query: 400 HKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKH 573
L+++A +F R + + NG+I + G W++QR+ + L++FG+ K
Sbjct: 94 LPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKK 153
Query: 574 SVSREKLEKRIASGVYEILENIEK 645
S LE+RI + E I++
Sbjct: 154 S-----LEERIQEEAQHLTEAIKE 172
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 80.6 bits (190), Expect = 4e-15
Identities = 43/144 (29%), Positives = 75/144 (52%), Gaps = 2/144 (1%)
Frame = +1
Query: 220 FKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSD 399
F K + +N PPGPW LP +G +D H+ + K YG ++ L++G I AV+++
Sbjct: 34 FLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITG 93
Query: 400 HKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKH 573
L+++A +F R + + NG+I + G W++QR+ + L++FG+ K
Sbjct: 94 LPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKK 153
Query: 574 SVSREKLEKRIASGVYEILENIEK 645
S LE+RI + E I++
Sbjct: 154 S-----LEERIQEEAQHLTEAIKE 172
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 80.6 bits (190), Expect = 4e-15
Identities = 43/144 (29%), Positives = 75/144 (52%), Gaps = 2/144 (1%)
Frame = +1
Query: 220 FKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSD 399
F K + +N PPGPW LP +G +D H+ + K YG ++ L++G I AV+++
Sbjct: 34 FLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITG 93
Query: 400 HKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKH 573
L+++A +F R + + NG+I + G W++QR+ + L++FG+ K
Sbjct: 94 LPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKK 153
Query: 574 SVSREKLEKRIASGVYEILENIEK 645
S LE+RI + E I++
Sbjct: 154 S-----LEERIQEEAQHLTEAIKE 172
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 80.6 bits (190), Expect = 4e-15
Identities = 43/144 (29%), Positives = 75/144 (52%), Gaps = 2/144 (1%)
Frame = +1
Query: 220 FKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSD 399
F K + +N PPGPW LP +G +D H+ + K YG ++ L++G I AV+++
Sbjct: 34 FLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITG 93
Query: 400 HKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKH 573
L+++A +F R + + NG+I + G W++QR+ + L++FG+ K
Sbjct: 94 LPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKK 153
Query: 574 SVSREKLEKRIASGVYEILENIEK 645
S LE+RI + E I++
Sbjct: 154 S-----LEERIQEEAQHLTEAIKE 172
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 80.6 bits (190), Expect = 4e-15
Identities = 43/144 (29%), Positives = 75/144 (52%), Gaps = 2/144 (1%)
Frame = +1
Query: 220 FKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSD 399
F K + +N PPGPW LP +G +D H+ + K YG ++ L++G I AV+++
Sbjct: 34 FLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITG 93
Query: 400 HKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKH 573
L+++A +F R + + NG+I + G W++QR+ + L++FG+ K
Sbjct: 94 LPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKK 153
Query: 574 SVSREKLEKRIASGVYEILENIEK 645
S LE+RI + E I++
Sbjct: 154 S-----LEERIQEEAQHLTEAIKE 172
>AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family 1
subfamily A polypeptide 1 protein.
Length = 483
Score = 79.4 bits (187), Expect = 1e-14
Identities = 46/173 (26%), Positives = 89/173 (51%), Gaps = 10/173 (5%)
Frame = +1
Query: 157 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 324
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATKFLLASVIFCLVFWVIRASRPQVPKGLENPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 325 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 498
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 499 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQE 176
>AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 79.4 bits (187), Expect = 1e-14
Identities = 46/173 (26%), Positives = 89/173 (51%), Gaps = 10/173 (5%)
Frame = +1
Query: 157 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 324
+S + + + V F FW+ + ++ + PPGPW P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWDWPLIGHMLTLGK-NPHLAL 63
Query: 325 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 498
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 499 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ G +W +R+L + LKSF ++ S LE+ ++ G ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKGAEVLISTLQE 176
>X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein.
Length = 512
Score = 79.0 bits (186), Expect = 1e-14
Identities = 46/173 (26%), Positives = 89/173 (51%), Gaps = 10/173 (5%)
Frame = +1
Query: 157 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 324
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 325 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 498
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 499 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQE 176
>X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein.
Length = 512
Score = 79.0 bits (186), Expect = 1e-14
Identities = 46/173 (26%), Positives = 89/173 (51%), Gaps = 10/173 (5%)
Frame = +1
Query: 157 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 324
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 325 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 498
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 499 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQE 176
>K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein.
Length = 512
Score = 79.0 bits (186), Expect = 1e-14
Identities = 46/173 (26%), Positives = 89/173 (51%), Gaps = 10/173 (5%)
Frame = +1
Query: 157 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 324
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVMRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 325 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 498
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 499 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQE 176
>EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 79.0 bits (186), Expect = 1e-14
Identities = 46/173 (26%), Positives = 89/173 (51%), Gaps = 10/173 (5%)
Frame = +1
Query: 157 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 324
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 325 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 498
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 499 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQE 176
>BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 79.0 bits (186), Expect = 1e-14
Identities = 46/173 (26%), Positives = 89/173 (51%), Gaps = 10/173 (5%)
Frame = +1
Query: 157 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 324
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 325 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 498
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 499 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQE 176
>AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1
variant protein.
Length = 484
Score = 79.0 bits (186), Expect = 1e-14
Identities = 46/173 (26%), Positives = 89/173 (51%), Gaps = 10/173 (5%)
Frame = +1
Query: 157 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 324
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 325 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 498
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 499 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQE 176
>AM236046-1|CAJ84703.1| 229|Homo sapiens cytochrome P450 1A1
protein.
Length = 229
Score = 79.0 bits (186), Expect = 1e-14
Identities = 46/173 (26%), Positives = 89/173 (51%), Gaps = 10/173 (5%)
Frame = +1
Query: 157 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 324
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 325 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 498
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 499 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQE 176
>AM233520-1|CAJ80723.1| 189|Homo sapiens cytochrome P450 1A1
protein.
Length = 189
Score = 79.0 bits (186), Expect = 1e-14
Identities = 46/173 (26%), Positives = 89/173 (51%), Gaps = 10/173 (5%)
Frame = +1
Query: 157 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 324
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 325 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 498
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 499 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQE 176
>AM233519-1|CAJ80722.1| 189|Homo sapiens cytochrome P450 1A1
protein.
Length = 189
Score = 79.0 bits (186), Expect = 1e-14
Identities = 46/173 (26%), Positives = 89/173 (51%), Gaps = 10/173 (5%)
Frame = +1
Query: 157 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 324
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 325 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 498
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 499 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQE 176
>AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein.
Length = 512
Score = 79.0 bits (186), Expect = 1e-14
Identities = 46/173 (26%), Positives = 89/173 (51%), Gaps = 10/173 (5%)
Frame = +1
Query: 157 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 324
+S + + + V F FW+ + ++ + PPGPWG P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWGWPLIGHMLTLGK-NPHLAL 63
Query: 325 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 498
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 499 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQE 176
>AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450
epoxygenase protein.
Length = 339
Score = 79.0 bits (186), Expect = 1e-14
Identities = 42/144 (29%), Positives = 75/144 (52%), Gaps = 2/144 (1%)
Frame = +1
Query: 220 FKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSD 399
F K + +N PPGPW LP +G +D H+ + K YG ++ L++G I AV+++
Sbjct: 3 FLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITG 62
Query: 400 HKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKH 573
L+++A +F R + + NG+I + G W++QR+ + L++FG+ K
Sbjct: 63 LPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGK- 121
Query: 574 SVSREKLEKRIASGVYEILENIEK 645
+ LE+RI + E I++
Sbjct: 122 ----KGLEERIQEEAQHLTEAIKE 141
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 77.8 bits (183), Expect = 3e-14
Identities = 47/136 (34%), Positives = 71/136 (52%), Gaps = 2/136 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 426
LPPGP LP++G + ID +LTNLSK YG ++ L G VVL +++V++A
Sbjct: 29 LPPGPTPLPVIGNILQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKEALI 88
Query: 427 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKT 648
R+ ++E + KT
Sbjct: 144 RVQEEARCLVEELRKT 159
>L39098-1|AAL31347.1| 160|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 160
Score = 77.8 bits (183), Expect = 3e-14
Identities = 47/136 (34%), Positives = 71/136 (52%), Gaps = 2/136 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 426
LPPGP LP++G + ID +LTNLSK YG ++ L G VVL +++V++A
Sbjct: 29 LPPGPTPLPVIGNILQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKEALI 88
Query: 427 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKT 648
R+ ++E + KT
Sbjct: 144 RVQEEARCLVEELRKT 159
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 77.8 bits (183), Expect = 3e-14
Identities = 47/136 (34%), Positives = 71/136 (52%), Gaps = 2/136 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 426
LPPGP LP++G + ID +LTNLSK YG ++ L G VVL +++V++A
Sbjct: 29 LPPGPTPLPVIGNILQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKEALI 88
Query: 427 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKT 648
R+ ++E + KT
Sbjct: 144 RVQEEARCLVEELRKT 159
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 77.8 bits (183), Expect = 3e-14
Identities = 47/136 (34%), Positives = 71/136 (52%), Gaps = 2/136 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 426
LPPGP LP++G + ID +LTNLSK YG ++ L G VVL +++V++A
Sbjct: 29 LPPGPTPLPVIGNILQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKEALI 88
Query: 427 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKT 648
R+ ++E + KT
Sbjct: 144 RVQEEARCLVEELRKT 159
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 77.8 bits (183), Expect = 3e-14
Identities = 47/136 (34%), Positives = 71/136 (52%), Gaps = 2/136 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 426
LPPGP LP++G + ID +LTNLSK YG ++ L G VVL +++V++A
Sbjct: 29 LPPGPTPLPVIGNILQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKEALI 88
Query: 427 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKT 648
R+ ++E + KT
Sbjct: 144 RVQEEARCLVEELRKT 159
>Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein.
Length = 490
Score = 77.4 bits (182), Expect = 4e-14
Identities = 46/154 (29%), Positives = 82/154 (53%), Gaps = 2/154 (1%)
Frame = +1
Query: 193 VTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMG 372
++F+ F ++++ + LPPGP LPI+G + ID + TN SK YG ++ + G
Sbjct: 11 LSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFG 70
Query: 373 SIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSW 546
VV ++ V++A + + FSGR ++ + G GII + G W++ R+ +
Sbjct: 71 MNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTT 130
Query: 547 LKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
L++FGM K S+ E R+ + ++E + KT
Sbjct: 131 LRNFGMGKRSI-----EDRVQEEAHCLVEELRKT 159
>M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein.
Length = 480
Score = 77.4 bits (182), Expect = 4e-14
Identities = 46/154 (29%), Positives = 82/154 (53%), Gaps = 2/154 (1%)
Frame = +1
Query: 193 VTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMG 372
++F+ F ++++ + LPPGP LPI+G + ID + TN SK YG ++ + G
Sbjct: 1 LSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFG 60
Query: 373 SIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSW 546
VV ++ V++A + + FSGR ++ + G GII + G W++ R+ +
Sbjct: 61 MNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTT 120
Query: 547 LKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
L++FGM K S+ E R+ + ++E + KT
Sbjct: 121 LRNFGMGKRSI-----EDRVQEEAHCLVEELRKT 149
>EF122242-1|ABO41977.1| 321|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 321
Score = 77.4 bits (182), Expect = 4e-14
Identities = 44/120 (36%), Positives = 63/120 (52%), Gaps = 2/120 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 423
LPPGP LPI+G L + +LT LSK YG++Y + +G VVLS ++ V++A
Sbjct: 30 LPPGPRPLPILGNLLLLCSQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVKEALV 89
Query: 424 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR GNGI + G W+ R+ L++FGM K S+ LE+
Sbjct: 90 DQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKRSIEERILEE 149
>AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 77.4 bits (182), Expect = 4e-14
Identities = 46/154 (29%), Positives = 82/154 (53%), Gaps = 2/154 (1%)
Frame = +1
Query: 193 VTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMG 372
++F+ F ++++ + LPPGP LPI+G + ID + TN SK YG ++ + G
Sbjct: 11 LSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFG 70
Query: 373 SIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSW 546
VV ++ V++A + + FSGR ++ + G GII + G W++ R+ +
Sbjct: 71 MNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTT 130
Query: 547 LKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
L++FGM K S+ E R+ + ++E + KT
Sbjct: 131 LRNFGMGKRSI-----EDRVQEEAHCLVEELRKT 159
>AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 77.4 bits (182), Expect = 4e-14
Identities = 46/154 (29%), Positives = 82/154 (53%), Gaps = 2/154 (1%)
Frame = +1
Query: 193 VTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMG 372
++F+ F ++++ + LPPGP LPI+G + ID + TN SK YG ++ + G
Sbjct: 11 LSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFG 70
Query: 373 SIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSW 546
VV ++ V++A + + FSGR ++ + G GII + G W++ R+ +
Sbjct: 71 MNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTT 130
Query: 547 LKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
L++FGM K S+ E R+ + ++E + KT
Sbjct: 131 LRNFGMGKRSI-----EDRVQEEAHCLVEELRKT 159
>J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrome
P450IIE1 (ethanol-inducible) gene, complete cds. ).
Length = 493
Score = 77.0 bits (181), Expect = 6e-14
Identities = 50/157 (31%), Positives = 83/157 (52%), Gaps = 2/157 (1%)
Frame = +1
Query: 184 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGL 363
+W F+ +++++ NLPPGP+ LPI+G L ++ + + T L++ +G ++ L
Sbjct: 12 VW-AAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTL 70
Query: 364 KMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLI 537
+GS VV+ +K V++A KD FSGR L H GII G W+D R+
Sbjct: 71 YVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHA-HRDRGIIFNNGPTWKDIRRFS 129
Query: 538 TSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
+ L+++GM K + E RI + +LE + KT
Sbjct: 130 LTTLRNYGMGK-----QGNESRIQREAHFLLEALRKT 161
>J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrome
P-450j mRNA, complete cds. ).
Length = 493
Score = 77.0 bits (181), Expect = 6e-14
Identities = 50/157 (31%), Positives = 83/157 (52%), Gaps = 2/157 (1%)
Frame = +1
Query: 184 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGL 363
+W F+ +++++ NLPPGP+ LPI+G L ++ + + T L++ +G ++ L
Sbjct: 12 VW-AAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTL 70
Query: 364 KMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLI 537
+GS VV+ +K V++A KD FSGR L H GII G W+D R+
Sbjct: 71 YVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHA-HRDRGIIFNNGPTWKDIRRFS 129
Query: 538 TSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
+ L+++GM K + E RI + +LE + KT
Sbjct: 130 LTTLRNYGMGK-----QGNESRIQREAHFLLEALRKT 161
>DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 77.0 bits (181), Expect = 6e-14
Identities = 50/157 (31%), Positives = 83/157 (52%), Gaps = 2/157 (1%)
Frame = +1
Query: 184 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGL 363
+W F+ +++++ NLPPGP+ LPI+G L ++ + + T L++ +G ++ L
Sbjct: 12 VW-AAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTL 70
Query: 364 KMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLI 537
+GS VV+ +K V++A KD FSGR L H GII G W+D R+
Sbjct: 71 YVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHA-HRDRGIIFNNGPTWKDIRRFS 129
Query: 538 TSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
+ L+++GM K + E RI + +LE + KT
Sbjct: 130 LTTLRNYGMGK-----QGNESRIQREAHFLLEALRKT 161
>DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1
protein.
Length = 493
Score = 77.0 bits (181), Expect = 6e-14
Identities = 50/157 (31%), Positives = 83/157 (52%), Gaps = 2/157 (1%)
Frame = +1
Query: 184 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGL 363
+W F+ +++++ NLPPGP+ LPI+G L ++ + + T L++ +G ++ L
Sbjct: 12 VW-AAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTL 70
Query: 364 KMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLI 537
+GS VV+ +K V++A KD FSGR L H GII G W+D R+
Sbjct: 71 YVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHA-HRDRGIIFNNGPTWKDIRRFS 129
Query: 538 TSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
+ L+++GM K + E RI + +LE + KT
Sbjct: 130 LTTLRNYGMGK-----QGNESRIQREAHFLLEALRKT 161
>BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 77.0 bits (181), Expect = 6e-14
Identities = 50/157 (31%), Positives = 83/157 (52%), Gaps = 2/157 (1%)
Frame = +1
Query: 184 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGL 363
+W F+ +++++ NLPPGP+ LPI+G L ++ + + T L++ +G ++ L
Sbjct: 12 VW-AAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTL 70
Query: 364 KMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLI 537
+GS VV+ +K V++A KD FSGR L H GII G W+D R+
Sbjct: 71 YVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHA-HRDRGIIFNNGPAWKDIRRFS 129
Query: 538 TSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
+ L+++GM K + E RI + +LE + KT
Sbjct: 130 LTTLRNYGMGK-----QGNESRIQREAHFLLEALRKT 161
>BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 77.0 bits (181), Expect = 6e-14
Identities = 46/154 (29%), Positives = 82/154 (53%), Gaps = 2/154 (1%)
Frame = +1
Query: 193 VTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMG 372
++F+ F ++++ + LPPGP LPI+G + ID + TN SK YG ++ + G
Sbjct: 11 LSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFG 70
Query: 373 SIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSW 546
VV ++ V++A + + FSGR ++ + G GII + G W++ R+ +
Sbjct: 71 MNPIVVFHGYESVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTT 130
Query: 547 LKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
L++FGM K S+ E R+ + ++E + KT
Sbjct: 131 LRNFGMGKRSI-----EDRVQEEAHCLVEELRKT 159
>AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 77.0 bits (181), Expect = 6e-14
Identities = 50/157 (31%), Positives = 83/157 (52%), Gaps = 2/157 (1%)
Frame = +1
Query: 184 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGL 363
+W F+ +++++ NLPPGP+ LPI+G L ++ + + T L++ +G ++ L
Sbjct: 12 VW-AAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTL 70
Query: 364 KMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLI 537
+GS VV+ +K V++A KD FSGR L H GII G W+D R+
Sbjct: 71 YVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHA-HRDRGIIFNNGPTWKDIRRFS 129
Query: 538 TSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
+ L+++GM K + E RI + +LE + KT
Sbjct: 130 LTTLRNYGMGK-----QGNESRIQREAHFLLEALRKT 161
>AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1
protein.
Length = 493
Score = 77.0 bits (181), Expect = 6e-14
Identities = 50/157 (31%), Positives = 83/157 (52%), Gaps = 2/157 (1%)
Frame = +1
Query: 184 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGL 363
+W F+ +++++ NLPPGP+ LPI+G L ++ + + T L++ +G ++ L
Sbjct: 12 VW-AAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTL 70
Query: 364 KMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLI 537
+GS VV+ +K V++A KD FSGR L H GII G W+D R+
Sbjct: 71 YVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHA-HRDRGIIFNNGPTWKDIRRFS 129
Query: 538 TSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
+ L+++GM K + E RI + +LE + KT
Sbjct: 130 LTTLRNYGMGK-----QGNESRIQREAHFLLEALRKT 161
>M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrome
P-450 1 mRNA, complete cds, clone Hp1-2. ).
Length = 393
Score = 76.6 bits (180), Expect = 7e-14
Identities = 46/154 (29%), Positives = 82/154 (53%), Gaps = 2/154 (1%)
Frame = +1
Query: 193 VTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMG 372
++F+ F ++++ + LPPGP LPI+G + ID + TN SK YG ++ + G
Sbjct: 11 LSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFG 70
Query: 373 SIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSW 546
VV ++ V++A + + FSGR ++ + G GII + G W++ R+ +
Sbjct: 71 MNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTN 130
Query: 547 LKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
L++FGM K S+ E R+ + ++E + KT
Sbjct: 131 LRNFGMGKRSI-----EDRVQEEAHCLVEELRKT 159
>M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome
P-450 1 functional form mRNA, complete cds. ).
Length = 490
Score = 76.6 bits (180), Expect = 7e-14
Identities = 46/154 (29%), Positives = 82/154 (53%), Gaps = 2/154 (1%)
Frame = +1
Query: 193 VTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMG 372
++F+ F ++++ + LPPGP LPI+G + ID + TN SK YG ++ + G
Sbjct: 11 LSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFG 70
Query: 373 SIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSW 546
VV ++ V++A + + FSGR ++ + G GII + G W++ R+ +
Sbjct: 71 MNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTN 130
Query: 547 LKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
L++FGM K S+ E R+ + ++E + KT
Sbjct: 131 LRNFGMGKRSI-----EDRVQEEAHCLVEELRKT 159
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 76.6 bits (180), Expect = 7e-14
Identities = 50/157 (31%), Positives = 83/157 (52%), Gaps = 2/157 (1%)
Frame = +1
Query: 184 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGL 363
+W F+ +++++ NLPPGP+ LPI+G L ++ + + T L++ +G ++ L
Sbjct: 12 VW-AAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTL 70
Query: 364 KMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLI 537
+GS VV+ +K V++A KD FSGR L H GII G W+D R+
Sbjct: 71 CVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHA-HRDRGIIFNNGPTWKDIRRFS 129
Query: 538 TSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
+ L+++GM K + E RI + +LE + KT
Sbjct: 130 LTTLRNYGMGK-----QGNESRIQREAHFLLEALRKT 161
>AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 76.2 bits (179), Expect = 1e-13
Identities = 45/173 (26%), Positives = 88/173 (50%), Gaps = 10/173 (5%)
Frame = +1
Query: 157 LSSNMDLYFIWLVTFVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITL 324
+S + + + V F FW+ + ++ + PPGPW P++G++ + + +PH+ L
Sbjct: 5 ISMSATEFLLASVIFCLVFWVIRASRPQVPKGLKNPPGPWDWPLIGHMLTLGK-NPHLAL 63
Query: 325 TNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIIC 498
+ +S+ YG + +++GS VVLS +R A + D F GR LY + NG +
Sbjct: 64 SRMSQQYGDVLQIRIGSTPVVVLSGLDTIRQALVRQGDDFKGRPDLYTFTLISNGQSMSF 123
Query: 499 A--EGGLWRDQRKLITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ G +W +R+L + LKSF ++ S LE+ ++ ++ +++
Sbjct: 124 SPDSGPVWAARRRLAQNGLKSFSIASDPASSTSCYLEEHVSKEAEVLISTLQE 176
>J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein.
Length = 491
Score = 74.1 bits (174), Expect = 4e-13
Identities = 43/120 (35%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 423
LPPGP L I+G L + +LT LSK YG++Y + +G VVLS ++ V++A
Sbjct: 30 LPPGPRPLSILGNLLLLCSQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVKEALV 89
Query: 424 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR GNGI + G W+ R+ L++FGM K S+ LE+
Sbjct: 90 DQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKRSIEERILEE 149
>EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 491
Score = 74.1 bits (174), Expect = 4e-13
Identities = 43/120 (35%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 423
LPPGP L I+G L + +LT LSK YG++Y + +G VVLS ++ V++A
Sbjct: 30 LPPGPRPLSILGNLLLLCSQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVKEALV 89
Query: 424 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR GNGI + G W+ R+ L++FGM K S+ LE+
Sbjct: 90 DQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKRSIEERILEE 149
>BC109056-1|AAI09057.1| 320|Homo sapiens CYP2F1 protein protein.
Length = 320
Score = 74.1 bits (174), Expect = 4e-13
Identities = 43/120 (35%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 423
LPPGP L I+G L + +LT LSK YG++Y + +G VVLS ++ V++A
Sbjct: 30 LPPGPRPLSILGNLLLLCSQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVKEALV 89
Query: 424 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR GNGI + G W+ R+ L++FGM K S+ LE+
Sbjct: 90 DQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKRSIEERILEE 149
>AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1
protein.
Length = 495
Score = 74.1 bits (174), Expect = 4e-13
Identities = 43/120 (35%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 423
LPPGP L I+G L + +LT LSK YG++Y + +G VVLS ++ V++A
Sbjct: 30 LPPGPRPLSILGNLLLLCSQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVKEALV 89
Query: 424 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR GNGI + G W+ R+ L++FGM K S+ LE+
Sbjct: 90 DQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKRSIEERILEE 149
>M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein.
Length = 462
Score = 73.7 bits (173), Expect = 5e-13
Identities = 43/136 (31%), Positives = 72/136 (52%), Gaps = 2/136 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 423
LPPGP LPI+G + ID + TN SK YG ++ + G VV ++ V++A
Sbjct: 1 LPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALI 60
Query: 424 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ + FSGR ++ + G GII + G W++ R+ + L++FGM K S+ E
Sbjct: 61 DNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSI-----ED 115
Query: 601 RIASGVYEILENIEKT 648
R+ + +++ + KT
Sbjct: 116 RVQEEAHCLVDELRKT 131
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 73.3 bits (172), Expect = 7e-13
Identities = 46/136 (33%), Positives = 69/136 (50%), Gaps = 2/136 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 426
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 16 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 75
Query: 427 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 76 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 130
Query: 601 RIASGVYEILENIEKT 648
R+ ++E + KT
Sbjct: 131 RVQEEARCLVEELRKT 146
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 73.3 bits (172), Expect = 7e-13
Identities = 46/136 (33%), Positives = 69/136 (50%), Gaps = 2/136 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 426
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 24 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 83
Query: 427 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 84 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 138
Query: 601 RIASGVYEILENIEKT 648
R+ ++E + KT
Sbjct: 139 RVQEEARCLVEELRKT 154
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 73.3 bits (172), Expect = 7e-13
Identities = 46/136 (33%), Positives = 69/136 (50%), Gaps = 2/136 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 426
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 24 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 83
Query: 427 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 84 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 138
Query: 601 RIASGVYEILENIEKT 648
R+ ++E + KT
Sbjct: 139 RVQEEARCLVEELRKT 154
>L16880-1|AAD13466.1| 273|Homo sapiens cytochrome P-450 2C protein.
Length = 273
Score = 73.3 bits (172), Expect = 7e-13
Identities = 46/136 (33%), Positives = 69/136 (50%), Gaps = 2/136 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 426
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 29 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 88
Query: 427 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKT 648
R+ ++E + KT
Sbjct: 144 RVQEEARCLVEELRKT 159
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 73.3 bits (172), Expect = 7e-13
Identities = 46/136 (33%), Positives = 69/136 (50%), Gaps = 2/136 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 426
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 26 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 85
Query: 427 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 86 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 140
Query: 601 RIASGVYEILENIEKT 648
R+ ++E + KT
Sbjct: 141 RVQEEARCLVEELRKT 156
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 73.3 bits (172), Expect = 7e-13
Identities = 46/136 (33%), Positives = 69/136 (50%), Gaps = 2/136 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 426
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 29 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 88
Query: 427 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKT 648
R+ ++E + KT
Sbjct: 144 RVQEEARCLVEELRKT 159
>BC020754-1|AAH20754.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 73.3 bits (172), Expect = 7e-13
Identities = 46/136 (33%), Positives = 69/136 (50%), Gaps = 2/136 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 426
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 29 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 88
Query: 427 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKT 648
R+ ++E + KT
Sbjct: 144 RVQEEARCLVEELRKT 159
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 73.3 bits (172), Expect = 7e-13
Identities = 46/136 (33%), Positives = 69/136 (50%), Gaps = 2/136 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 426
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 29 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 88
Query: 427 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKT 648
R+ ++E + KT
Sbjct: 144 RVQEEARCLVEELRKT 159
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 73.3 bits (172), Expect = 7e-13
Identities = 46/136 (33%), Positives = 69/136 (50%), Gaps = 2/136 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 426
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 29 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 88
Query: 427 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKT 648
R+ ++E + KT
Sbjct: 144 RVQEEARCLVEELRKT 159
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 73.3 bits (172), Expect = 7e-13
Identities = 46/136 (33%), Positives = 69/136 (50%), Gaps = 2/136 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 426
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 29 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 88
Query: 427 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR L G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKT 648
R+ ++E + KT
Sbjct: 144 RVQEEARCLVEELRKT 159
>AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1
protein.
Length = 462
Score = 73.3 bits (172), Expect = 7e-13
Identities = 47/136 (34%), Positives = 73/136 (53%), Gaps = 2/136 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 423
LPPGP+ LPI+G L ++ + + T L++ +G ++ L +GS VV+ +K V++A
Sbjct: 1 LPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVKEALL 60
Query: 424 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
KD FSGR L H GII G W+D R+ + L+++GM K + E
Sbjct: 61 DYKDEFSGRGDLPAFHA-HRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGK-----QGNES 114
Query: 601 RIASGVYEILENIEKT 648
RI + +LE + KT
Sbjct: 115 RIQREAHFLLEALRKT 130
>BC070317-1|AAH70317.1| 162|Homo sapiens CYP2C9 protein protein.
Length = 162
Score = 71.7 bits (168), Expect = 2e-12
Identities = 41/113 (36%), Positives = 60/113 (53%), Gaps = 2/113 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS 426
LPPGP LP++G + I +LTNLSK YG ++ L G VVL ++ V++A
Sbjct: 29 LPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALI 88
Query: 427 K--DSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSV 579
+ FSGR L G GI+ + G W++ R+ L++FGM K S+
Sbjct: 89 DLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI 141
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 70.9 bits (166), Expect = 4e-12
Identities = 43/137 (31%), Positives = 70/137 (51%), Gaps = 2/137 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 423
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 424 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR + + G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKTS 651
R+ ++E + KT+
Sbjct: 144 RVQEEARCLVEELRKTN 160
>L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18
protein.
Length = 490
Score = 70.9 bits (166), Expect = 4e-12
Identities = 43/137 (31%), Positives = 70/137 (51%), Gaps = 2/137 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 423
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 424 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR + + G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKTS 651
R+ ++E + KT+
Sbjct: 144 RVQEEARCLVEELRKTN 160
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 70.9 bits (166), Expect = 4e-12
Identities = 43/137 (31%), Positives = 70/137 (51%), Gaps = 2/137 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 423
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 424 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR + + G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKTS 651
R+ ++E + KT+
Sbjct: 144 RVQEEARCLVEELRKTN 160
>BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein.
Length = 443
Score = 70.9 bits (166), Expect = 4e-12
Identities = 43/137 (31%), Positives = 70/137 (51%), Gaps = 2/137 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 423
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 424 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR + + G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKTS 651
R+ ++E + KT+
Sbjct: 144 RVQEEARCLVEELRKTN 160
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 70.9 bits (166), Expect = 4e-12
Identities = 43/137 (31%), Positives = 70/137 (51%), Gaps = 2/137 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 423
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 424 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR + + G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKTS 651
R+ ++E + KT+
Sbjct: 144 RVQEEARCLVEELRKTN 160
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 70.9 bits (166), Expect = 4e-12
Identities = 43/137 (31%), Positives = 70/137 (51%), Gaps = 2/137 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 423
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 424 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR + + G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKTS 651
R+ ++E + KT+
Sbjct: 144 RVQEEARCLVEELRKTN 160
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 70.9 bits (166), Expect = 4e-12
Identities = 43/137 (31%), Positives = 70/137 (51%), Gaps = 2/137 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 423
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 424 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR + + G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKTS 651
R+ ++E + KT+
Sbjct: 144 RVQEEARCLVEELRKTN 160
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 70.9 bits (166), Expect = 4e-12
Identities = 43/137 (31%), Positives = 70/137 (51%), Gaps = 2/137 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 423
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 424 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR + + G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKTS 651
R+ ++E + KT+
Sbjct: 144 RVQEEARCLVEELRKTN 160
>AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2
protein.
Length = 516
Score = 70.9 bits (166), Expect = 4e-12
Identities = 40/159 (25%), Positives = 82/159 (51%), Gaps = 10/159 (6%)
Frame = +1
Query: 199 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 366
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 367 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 534
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 535 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ L +F ++ S LE+ ++ ++ +++
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAMALISRLQE 178
>Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for
cytochrome P-3-450. ).
Length = 515
Score = 70.5 bits (165), Expect = 5e-12
Identities = 40/159 (25%), Positives = 82/159 (51%), Gaps = 10/159 (6%)
Frame = +1
Query: 199 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 366
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 367 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 534
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 535 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ L +F ++ S LE+ ++ ++ +++
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQE 178
>M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein.
Length = 515
Score = 70.5 bits (165), Expect = 5e-12
Identities = 40/159 (25%), Positives = 82/159 (51%), Gaps = 10/159 (6%)
Frame = +1
Query: 199 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 366
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 367 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 534
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 535 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ L +F ++ S LE+ ++ ++ +++
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQE 178
>M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein.
Length = 515
Score = 70.5 bits (165), Expect = 5e-12
Identities = 40/159 (25%), Positives = 82/159 (51%), Gaps = 10/159 (6%)
Frame = +1
Query: 199 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 366
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 367 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 534
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 535 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ L +F ++ S LE+ ++ ++ +++
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQE 178
>DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 70.5 bits (165), Expect = 5e-12
Identities = 40/159 (25%), Positives = 82/159 (51%), Gaps = 10/159 (6%)
Frame = +1
Query: 199 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 366
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 367 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 534
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 535 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ L +F ++ S LE+ ++ ++ +++
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQE 178
>BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 70.5 bits (165), Expect = 5e-12
Identities = 40/159 (25%), Positives = 82/159 (51%), Gaps = 10/159 (6%)
Frame = +1
Query: 199 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 366
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 367 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 534
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 535 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ L +F ++ S LE+ ++ ++ +++
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQE 178
>BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 70.5 bits (165), Expect = 5e-12
Identities = 40/159 (25%), Positives = 82/159 (51%), Gaps = 10/159 (6%)
Frame = +1
Query: 199 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 366
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 367 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 534
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 535 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ L +F ++ S LE+ ++ ++ +++
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQE 178
>BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 70.5 bits (165), Expect = 5e-12
Identities = 40/159 (25%), Positives = 82/159 (51%), Gaps = 10/159 (6%)
Frame = +1
Query: 199 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 366
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 367 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 534
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 535 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ L +F ++ S LE+ ++ ++ +++
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQE 178
>BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 70.5 bits (165), Expect = 5e-12
Identities = 40/159 (25%), Positives = 82/159 (51%), Gaps = 10/159 (6%)
Frame = +1
Query: 199 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 366
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 367 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 534
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 535 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ L +F ++ S LE+ ++ ++ +++
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQE 178
>BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 70.5 bits (165), Expect = 5e-12
Identities = 40/159 (25%), Positives = 82/159 (51%), Gaps = 10/159 (6%)
Frame = +1
Query: 199 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 366
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 367 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 534
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 535 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ L +F ++ S LE+ ++ ++ +++
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQE 178
>AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 70.5 bits (165), Expect = 5e-12
Identities = 40/159 (25%), Positives = 82/159 (51%), Gaps = 10/159 (6%)
Frame = +1
Query: 199 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 366
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 367 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 534
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 535 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ L +F ++ S LE+ ++ ++ +++
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQE 178
>L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrome
P-450 4 gene, exon 7, and three Alu repeats in the 3'
flank. ).
Length = 516
Score = 69.7 bits (163), Expect = 8e-12
Identities = 40/159 (25%), Positives = 81/159 (50%), Gaps = 10/159 (6%)
Frame = +1
Query: 199 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 366
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + +
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIS 79
Query: 367 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 534
+GS +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 535 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ L +F ++ S LE+ ++ ++ +++
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQE 178
>M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein.
Length = 491
Score = 68.5 bits (160), Expect = 2e-11
Identities = 44/160 (27%), Positives = 77/160 (48%), Gaps = 2/160 (1%)
Frame = +1
Query: 175 LYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAI 354
L F+ L+T + + + LPPGP LP++G L +DR + + YG +
Sbjct: 6 LLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV 65
Query: 355 YGLKMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQR 528
+ + +G V+L + +R+A ++FSGR + + G G+I A G W+ R
Sbjct: 66 FTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLR 125
Query: 529 KLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
+ + ++ FGM K SV E+RI ++E + K+
Sbjct: 126 RFSVTTMRDFGMGKRSV-----EERIQEEAQCLIEELRKS 160
>DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 68.5 bits (160), Expect = 2e-11
Identities = 44/160 (27%), Positives = 77/160 (48%), Gaps = 2/160 (1%)
Frame = +1
Query: 175 LYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAI 354
L F+ L+T + + + LPPGP LP++G L +DR + + YG +
Sbjct: 6 LLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV 65
Query: 355 YGLKMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQR 528
+ + +G V+L + +R+A ++FSGR + + G G+I A G W+ R
Sbjct: 66 FTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLR 125
Query: 529 KLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
+ + ++ FGM K SV E+RI ++E + K+
Sbjct: 126 RFSVTTMRDFGMGKRSV-----EERIQEEAQCLIEELRKS 160
>BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 68.5 bits (160), Expect = 2e-11
Identities = 44/160 (27%), Positives = 77/160 (48%), Gaps = 2/160 (1%)
Frame = +1
Query: 175 LYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAI 354
L F+ L+T + + + LPPGP LP++G L +DR + + YG +
Sbjct: 6 LLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV 65
Query: 355 YGLKMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQR 528
+ + +G V+L + +R+A ++FSGR + + G G+I A G W+ R
Sbjct: 66 FTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLR 125
Query: 529 KLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
+ + ++ FGM K SV E+RI ++E + K+
Sbjct: 126 RFSVTTMRDFGMGKRSV-----EERIQEEAQCLIEELRKS 160
>BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 68.5 bits (160), Expect = 2e-11
Identities = 44/160 (27%), Positives = 77/160 (48%), Gaps = 2/160 (1%)
Frame = +1
Query: 175 LYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAI 354
L F+ L+T + + + LPPGP LP++G L +DR + + YG +
Sbjct: 6 LLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV 65
Query: 355 YGLKMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQR 528
+ + +G V+L + +R+A ++FSGR + + G G+I A G W+ R
Sbjct: 66 FTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLR 125
Query: 529 KLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
+ + ++ FGM K SV E+RI ++E + K+
Sbjct: 126 RFSVTTMRDFGMGKRSV-----EERIQEEAQCLIEELRKS 160
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 68.5 bits (160), Expect = 2e-11
Identities = 42/137 (30%), Positives = 69/137 (50%), Gaps = 2/137 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 423
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 424 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ F GR + + G GI+ + G W++ R+ L++FGM K S+ E
Sbjct: 89 DHGEEFFGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKTS 651
R+ ++E + KT+
Sbjct: 144 RVQEEARCLVEELRKTN 160
>AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein.
Length = 491
Score = 68.5 bits (160), Expect = 2e-11
Identities = 44/160 (27%), Positives = 77/160 (48%), Gaps = 2/160 (1%)
Frame = +1
Query: 175 LYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAI 354
L F+ L+T + + + LPPGP LP++G L +DR + + YG +
Sbjct: 6 LLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV 65
Query: 355 YGLKMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQR 528
+ + +G V+L + +R+A ++FSGR + + G G+I A G W+ R
Sbjct: 66 FTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLR 125
Query: 529 KLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
+ + ++ FGM K SV E+RI ++E + K+
Sbjct: 126 RFSVTTMRDFGMGKRSV-----EERIQEEAQCLIEELRKS 160
>S63426-1|ABB76283.1| 214|Homo sapiens (S)-mephenytoin hydroxylase
associated cytochrome P450 protein.
Length = 214
Score = 67.7 bits (158), Expect = 3e-11
Identities = 42/137 (30%), Positives = 69/137 (50%), Gaps = 2/137 (1%)
Frame = +1
Query: 247 LPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF- 423
LP GP LPI+G + +D +LTN SK YG ++ + G VVL ++ V++A
Sbjct: 29 LPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALI 88
Query: 424 -SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ FSGR + + G GI+ + G W++ + L++FGM K S+ E
Sbjct: 89 DHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIWRFCLMTLRNFGMGKRSI-----ED 143
Query: 601 RIASGVYEILENIEKTS 651
R+ ++E + KT+
Sbjct: 144 RVQEEARCLVEELRKTN 160
>BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 67.7 bits (158), Expect = 3e-11
Identities = 39/159 (24%), Positives = 81/159 (50%), Gaps = 10/159 (6%)
Frame = +1
Query: 199 FVAGFWIFK----KIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLK 366
F FW+ K ++ + PP PWG P++G++ + + +PH+ L+ +S+ YG + ++
Sbjct: 21 FCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGK-NPHLALSRMSQRYGDVLQIR 79
Query: 367 MGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICA--EGGLWRDQRKL 534
+ S +VLS +R A + D F GR LY + + +G + + G +W +R+L
Sbjct: 80 IDSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRL 139
Query: 535 ITSWLKSFGMSKHSVSREK--LEKRIASGVYEILENIEK 645
+ L +F ++ S LE+ ++ ++ +++
Sbjct: 140 AQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQE 178
>AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6
protein.
Length = 491
Score = 67.7 bits (158), Expect = 3e-11
Identities = 40/144 (27%), Positives = 69/144 (47%), Gaps = 2/144 (1%)
Frame = +1
Query: 175 LYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAI 354
L F+ L+T + + + LPPGP LP++G L +DR + + YG +
Sbjct: 6 LLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV 65
Query: 355 YGLKMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQR 528
+ + +G V+L + +R+A ++FSGR + + G G+I A G W+ R
Sbjct: 66 FTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLR 125
Query: 529 KLITSWLKSFGMSKHSVSREKLEK 600
+ + ++ FGM K SV E+
Sbjct: 126 RFSVTTMRDFGMGKRSVEERTQEE 149
>M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein.
Length = 377
Score = 66.9 bits (156), Expect = 6e-11
Identities = 43/160 (26%), Positives = 79/160 (49%), Gaps = 2/160 (1%)
Frame = +1
Query: 175 LYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAI 354
L F+ L+T + + + LPPGP LP++G L +DR + + YG +
Sbjct: 6 LLFLALLTGLLLLLVQRHPNSHGTLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV 65
Query: 355 YGLKMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQR 528
+ + +G V+L + +R+A + ++FSGR + + + G G++ A G W+ R
Sbjct: 66 FTVHLGPRPVVMLCGVEAIREALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWKVLR 125
Query: 529 KLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
+ + ++ FGM K SV E+RI ++E + K+
Sbjct: 126 RFSVTTMRDFGMGKRSV-----EERIQDEAQCLIEELRKS 160
>BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein.
Length = 377
Score = 66.9 bits (156), Expect = 6e-11
Identities = 43/160 (26%), Positives = 79/160 (49%), Gaps = 2/160 (1%)
Frame = +1
Query: 175 LYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAI 354
L F+ L+T + + + LPPGP LP++G L +DR + + YG +
Sbjct: 6 LLFLALLTGLLLLLVQRHPNSHGTLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDV 65
Query: 355 YGLKMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQR 528
+ + +G V+L + +R+A + ++FSGR + + + G G++ A G W+ R
Sbjct: 66 FTVHLGPRPVVMLCGVEAIREALVDNAEAFSGRGKIVIMDPVYQGYGMLFANGNRWKVLR 125
Query: 529 KLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
+ + ++ FGM K SV E+RI ++E + K+
Sbjct: 126 RFSVTTMRDFGMGKRSV-----EERIQDEAQCLIEELRKS 160
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 63.7 bits (148), Expect = 5e-10
Identities = 38/112 (33%), Positives = 57/112 (50%), Gaps = 3/112 (2%)
Frame = +1
Query: 244 NLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIY-AVVLSDHKLVRDA 420
+LPPGP LP++G L + + L LSK YG ++ + +G VVL + VR+A
Sbjct: 31 HLPPGPTPLPLLGNLLQLRPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVREA 90
Query: 421 FS--KDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
+ FSGR + + G +G+G+ + G WR RK L+ GM K
Sbjct: 91 LGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGK 142
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 63.7 bits (148), Expect = 5e-10
Identities = 38/112 (33%), Positives = 57/112 (50%), Gaps = 3/112 (2%)
Frame = +1
Query: 244 NLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIY-AVVLSDHKLVRDA 420
+LPPGP LP++G L + + L LSK YG ++ + +G VVL + VR+A
Sbjct: 31 HLPPGPTPLPLLGNLLQLRPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVREA 90
Query: 421 FS--KDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
+ FSGR + + G +G+G+ + G WR RK L+ GM K
Sbjct: 91 LGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGK 142
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 63.7 bits (148), Expect = 5e-10
Identities = 38/112 (33%), Positives = 57/112 (50%), Gaps = 3/112 (2%)
Frame = +1
Query: 244 NLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIY-AVVLSDHKLVRDA 420
+LPPGP LP++G L + + L LSK YG ++ + +G VVL + VR+A
Sbjct: 31 HLPPGPTPLPLLGNLLQLRPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVREA 90
Query: 421 FS--KDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
+ FSGR + + G +G+G+ + G WR RK L+ GM K
Sbjct: 91 LGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGK 142
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 63.7 bits (148), Expect = 5e-10
Identities = 38/112 (33%), Positives = 57/112 (50%), Gaps = 3/112 (2%)
Frame = +1
Query: 244 NLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIY-AVVLSDHKLVRDA 420
+LPPGP LP++G L + + L LSK YG ++ + +G VVL + VR+A
Sbjct: 31 HLPPGPTPLPLLGNLLQLRPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVREA 90
Query: 421 FS--KDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
+ FSGR + + G +G+G+ + G WR RK L+ GM K
Sbjct: 91 LGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGK 142
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 62.5 bits (145), Expect = 1e-09
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 5/144 (3%)
Frame = +1
Query: 184 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVG--YLPFIDRYHPHITLTNLSKTYGAIY 357
++L+ F G K + PPGP GLP +G Y PH+ + S+ YG I+
Sbjct: 18 LFLLLFALGVRQLLKQRRPMGFPPGPPGLPFIGNIYSLAASSELPHVYMRKQSQVYGEIF 77
Query: 358 GLKMGSIYAVVLSDHKLVRDAFSKDS--FSGRAPLYLTHGLMNGNGIICAEGGL-WRDQR 528
L +G I VVL+ + +V++ S F+ R L L + G++ + G W D R
Sbjct: 78 SLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHR 137
Query: 529 KLITSWLKSFGMSKHSVSREKLEK 600
+L + + FG + S + LE+
Sbjct: 138 RLAVNSFRYFGYGQKSFESKILEE 161
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 62.5 bits (145), Expect = 1e-09
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 5/144 (3%)
Frame = +1
Query: 184 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVG--YLPFIDRYHPHITLTNLSKTYGAIY 357
++L+ F G K + PPGP GLP +G Y PH+ + S+ YG I+
Sbjct: 18 LFLLLFALGVRQLLKQRRPMGFPPGPPGLPFIGNIYSLAASSELPHVYMRKQSQVYGEIF 77
Query: 358 GLKMGSIYAVVLSDHKLVRDAFSKDS--FSGRAPLYLTHGLMNGNGIICAEGGL-WRDQR 528
L +G I VVL+ + +V++ S F+ R L L + G++ + G W D R
Sbjct: 78 SLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHR 137
Query: 529 KLITSWLKSFGMSKHSVSREKLEK 600
+L + + FG + S + LE+
Sbjct: 138 RLAVNSFRYFGYGQKSFESKILEE 161
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 62.5 bits (145), Expect = 1e-09
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 5/144 (3%)
Frame = +1
Query: 184 IWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVG--YLPFIDRYHPHITLTNLSKTYGAIY 357
++L+ F G K + PPGP GLP +G Y PH+ + S+ YG I+
Sbjct: 18 LFLLLFALGVRQLLKQRRPMGFPPGPPGLPFIGNIYSLAASSELPHVYMRKQSQVYGEIF 77
Query: 358 GLKMGSIYAVVLSDHKLVRDAFSKDS--FSGRAPLYLTHGLMNGNGIICAEGGL-WRDQR 528
L +G I VVL+ + +V++ S F+ R L L + G++ + G W D R
Sbjct: 78 SLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHR 137
Query: 529 KLITSWLKSFGMSKHSVSREKLEK 600
+L + + FG + S + LE+
Sbjct: 138 RLAVNSFRYFGYGQKSFESKILEE 161
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 50/155 (32%), Positives = 75/155 (48%), Gaps = 6/155 (3%)
Frame = +1
Query: 172 DLYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRY-HPHITLTNLSKTYG 348
+L + L+T FW K+ P LP+VG LPF+ R+ H H L K YG
Sbjct: 3 ELVALLLLTLAYLFWP-KRRWPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYG 61
Query: 349 AIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGN--GIICAEGGL- 513
IY ++MG+ V++ H+L ++ K FSGR P T + + N GI A+ G
Sbjct: 62 PIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR-PQMATLDIASNNRKGIAFADSGAH 120
Query: 514 WRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGV 618
W+ R+L + +F + K +KLEK I +
Sbjct: 121 WQLHRRLA---MATFALFKD--GDQKLEKIICQEI 150
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 50/155 (32%), Positives = 75/155 (48%), Gaps = 6/155 (3%)
Frame = +1
Query: 172 DLYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRY-HPHITLTNLSKTYG 348
+L + L+T FW K+ P LP+VG LPF+ R+ H H L K YG
Sbjct: 3 ELVALLLLTLAYLFWP-KRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYG 61
Query: 349 AIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGN--GIICAEGGL- 513
IY ++MG+ V++ H+L ++ K FSGR P T + + N GI A+ G
Sbjct: 62 PIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR-PQMATLDIASNNRKGIAFADSGAH 120
Query: 514 WRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGV 618
W+ R+L + +F + K +KLEK I +
Sbjct: 121 WQLHRRLA---MATFALFKD--GDQKLEKIICQEI 150
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 50/155 (32%), Positives = 75/155 (48%), Gaps = 6/155 (3%)
Frame = +1
Query: 172 DLYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRY-HPHITLTNLSKTYG 348
+L + L+T FW K+ P LP+VG LPF+ R+ H H L K YG
Sbjct: 3 ELVALLLLTLAYLFWP-KRRWPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYG 61
Query: 349 AIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGN--GIICAEGGL- 513
IY ++MG+ V++ H+L ++ K FSGR P T + + N GI A+ G
Sbjct: 62 PIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR-PQMATLDIASNNRKGIAFADSGAH 120
Query: 514 WRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGV 618
W+ R+L + +F + K +KLEK I +
Sbjct: 121 WQLHRRLA---MATFALFKD--GDQKLEKIICQEI 150
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 50/155 (32%), Positives = 75/155 (48%), Gaps = 6/155 (3%)
Frame = +1
Query: 172 DLYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRY-HPHITLTNLSKTYG 348
+L + L+T FW K+ P LP+VG LPF+ R+ H H L K YG
Sbjct: 3 ELVALLLLTLAYLFWP-KRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYG 61
Query: 349 AIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGN--GIICAEGGL- 513
IY ++MG+ V++ H+L ++ K FSGR P T + + N GI A+ G
Sbjct: 62 PIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR-PQMATLDIASNNRKGIAFADSGAH 120
Query: 514 WRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGV 618
W+ R+L + +F + K +KLEK I +
Sbjct: 121 WQLHRRLA---MATFALFKD--GDQKLEKIICQEI 150
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 50/155 (32%), Positives = 75/155 (48%), Gaps = 6/155 (3%)
Frame = +1
Query: 172 DLYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRY-HPHITLTNLSKTYG 348
+L + L+T FW K+ P LP+VG LPF+ R+ H H L K YG
Sbjct: 3 ELVALLLLTLAYLFWP-KRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYG 61
Query: 349 AIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGN--GIICAEGGL- 513
IY ++MG+ V++ H+L ++ K FSGR P T + + N GI A+ G
Sbjct: 62 PIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR-PQMATLDIASNNRKGIAFADSGAH 120
Query: 514 WRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGV 618
W+ R+L + +F + K +KLEK I +
Sbjct: 121 WQLHRRLA---MATFALFKD--GDQKLEKIICQEI 150
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 50/155 (32%), Positives = 75/155 (48%), Gaps = 6/155 (3%)
Frame = +1
Query: 172 DLYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRY-HPHITLTNLSKTYG 348
+L + L+T FW K+ P LP+VG LPF+ R+ H H L K YG
Sbjct: 3 ELVALLLLTLAYLFWP-KRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYG 61
Query: 349 AIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGN--GIICAEGGL- 513
IY ++MG+ V++ H+L ++ K FSGR P T + + N GI A+ G
Sbjct: 62 PIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR-PQMATLDIASNNRKGIAFADSGAH 120
Query: 514 WRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGV 618
W+ R+L + +F + K +KLEK I +
Sbjct: 121 WQLHRRLA---MATFALFKD--GDQKLEKIICQEI 150
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 50/155 (32%), Positives = 75/155 (48%), Gaps = 6/155 (3%)
Frame = +1
Query: 172 DLYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRY-HPHITLTNLSKTYG 348
+L + L+T FW K+ P LP+VG LPF+ R+ H H L K YG
Sbjct: 3 ELVALLLLTLAYLFWP-KRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYG 61
Query: 349 AIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGN--GIICAEGGL- 513
IY ++MG+ V++ H+L ++ K FSGR P T + + N GI A+ G
Sbjct: 62 PIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR-PQMATLDIASNNRKGIAFADSGAH 120
Query: 514 WRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGV 618
W+ R+L + +F + K +KLEK I +
Sbjct: 121 WQLHRRLA---MATFALFKD--GDQKLEKIICQEI 150
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 50/155 (32%), Positives = 75/155 (48%), Gaps = 6/155 (3%)
Frame = +1
Query: 172 DLYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRY-HPHITLTNLSKTYG 348
+L + L+T FW K+ P LP+VG LPF+ R+ H H L K YG
Sbjct: 3 ELVALLLLTLAYLFWP-KRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYG 61
Query: 349 AIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGN--GIICAEGGL- 513
IY ++MG+ V++ H+L ++ K FSGR P T + + N GI A+ G
Sbjct: 62 PIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR-PQMATLDIASNNRKGIAFADSGAH 120
Query: 514 WRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGV 618
W+ R+L + +F + K +KLEK I +
Sbjct: 121 WQLHRRLA---MATFALFKD--GDQKLEKIICQEI 150
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 50/155 (32%), Positives = 75/155 (48%), Gaps = 6/155 (3%)
Frame = +1
Query: 172 DLYFIWLVTFVAGFWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRY-HPHITLTNLSKTYG 348
+L + L+T FW K+ P LP+VG LPF+ R+ H H L K YG
Sbjct: 3 ELVALLLLTLAYLFWP-KRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYG 61
Query: 349 AIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGN--GIICAEGGL- 513
IY ++MG+ V++ H+L ++ K FSGR P T + + N GI A+ G
Sbjct: 62 PIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGR-PQMATLDIASNNRKGIAFADSGAH 120
Query: 514 WRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGV 618
W+ R+L + +F + K +KLEK I +
Sbjct: 121 WQLHRRLA---MATFALFKD--GDQKLEKIICQEI 150
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 61.3 bits (142), Expect = 3e-09
Identities = 34/130 (26%), Positives = 65/130 (50%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H VR+A + FSGR + G G++ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGK 142
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 143 RGI-EERIQE 151
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 61.3 bits (142), Expect = 3e-09
Identities = 34/130 (26%), Positives = 65/130 (50%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 18 VWQQRKNKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 77
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H VR+A + FSGR + G G++ + G + R+ + L+ FG+ K
Sbjct: 78 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGK 137
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 138 RGI-EERIQE 146
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 61.3 bits (142), Expect = 3e-09
Identities = 34/130 (26%), Positives = 65/130 (50%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H VR+A + FSGR + G G++ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGK 142
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 143 RGI-EERIQE 151
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 61.3 bits (142), Expect = 3e-09
Identities = 34/130 (26%), Positives = 65/130 (50%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H VR+A + FSGR + G G++ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGK 142
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 143 RGI-EERIQE 151
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 61.3 bits (142), Expect = 3e-09
Identities = 34/130 (26%), Positives = 65/130 (50%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H VR+A + FSGR + G G++ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGK 142
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 143 RGI-EERIQE 151
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 61.3 bits (142), Expect = 3e-09
Identities = 34/130 (26%), Positives = 65/130 (50%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H VR+A + FSGR + G G++ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGK 142
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 143 RGI-EERIQE 151
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 61.3 bits (142), Expect = 3e-09
Identities = 34/130 (26%), Positives = 65/130 (50%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H VR+A + FSGR + G G++ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGK 142
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 143 RGI-EERIQE 151
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 61.3 bits (142), Expect = 3e-09
Identities = 34/130 (26%), Positives = 65/130 (50%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H VR+A + FSGR + G G++ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGK 142
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 143 RGI-EERIQE 151
>BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family 2,
subfamily W, polypeptide 1 protein.
Length = 490
Score = 60.5 bits (140), Expect = 5e-09
Identities = 34/119 (28%), Positives = 59/119 (49%), Gaps = 2/119 (1%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFS- 426
PPGP LP+VG L + +L LS+ YG ++ + +G VVL+ + V++A +
Sbjct: 32 PPGPRPLPLVGNLHLLRLSQQDRSLMELSERYGPVFTVHLGRQKTVVLTGFEAVKEALAG 91
Query: 427 -KDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ R P+ + + G GI + G WR R+ L S G+ + V+ + L++
Sbjct: 92 PGQELADRPPIAIFQLIQRGGGIFFSSGARWRAARQFTVRALHSLGVGREPVADKILQE 150
>U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 60.1 bits (139), Expect = 7e-09
Identities = 34/130 (26%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H V++A + FSGR L G G+ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGK 142
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 143 RGI-EERIQE 151
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 60.1 bits (139), Expect = 7e-09
Identities = 34/130 (26%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H V++A + FSGR L G G+ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGK 142
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 143 RGI-EERIQE 151
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 60.1 bits (139), Expect = 7e-09
Identities = 34/130 (26%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H V++A + FSGR L G G+ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGK 142
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 143 RGI-EERIQE 151
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 60.1 bits (139), Expect = 7e-09
Identities = 34/130 (26%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H V++A + FSGR L G G+ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGK 142
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 143 RGI-EERIQE 151
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 60.1 bits (139), Expect = 7e-09
Identities = 34/130 (26%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H V++A + FSGR L G G+ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGK 142
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 143 RGI-EERIQE 151
>AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13
variant 1 protein.
Length = 494
Score = 60.1 bits (139), Expect = 7e-09
Identities = 34/130 (26%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H V++A + FSGR L G G+ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGK 142
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 143 RGI-EERIQE 151
>AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13
protein.
Length = 494
Score = 60.1 bits (139), Expect = 7e-09
Identities = 34/130 (26%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H V++A + FSGR L G G+ + G + R+ + L+ FG+ K
Sbjct: 83 GHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGK 142
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 143 RGI-EERIQE 151
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 58.8 bits (136), Expect = 2e-08
Identities = 33/130 (25%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H VR+A + FSGR + G G++ + G + + + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLLRFAIATLRDFGVGK 142
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 143 RGI-EERIQE 151
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 58.4 bits (135), Expect = 2e-08
Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 3/100 (3%)
Frame = +1
Query: 310 PHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSKDS--FSGRAPLYLTHGLMNG 483
P + L +L++ YG+I+ +G VVLSD VR+A + + FS R + L +
Sbjct: 103 PQVLLAHLARVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVTKE 162
Query: 484 NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
G++ A G +WR QRK S L+ FG+ K S+ + +E+
Sbjct: 163 KGVVFAHYGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEE 202
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 58.4 bits (135), Expect = 2e-08
Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 3/100 (3%)
Frame = +1
Query: 310 PHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSKDS--FSGRAPLYLTHGLMNG 483
P + L +L++ YG+I+ +G VVLSD VR+A + + FS R + L +
Sbjct: 103 PQVLLAHLARVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVTKE 162
Query: 484 NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
G++ A G +WR QRK S L+ FG+ K S+ + +E+
Sbjct: 163 KGVVFAHYGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEE 202
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 58.0 bits (134), Expect = 3e-08
Identities = 34/130 (26%), Positives = 63/130 (48%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ H ++ S+ YG ++ + +G AVVL
Sbjct: 23 VWQQRKSRGKLPPGPTPLPFIGNYLQLNTEHICDSIMKFSECYGPVFTIHLGPRRAVVLC 82
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H VR+A + FSGR + G G+ + G + + + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVAFSNGERAKQLLRFAIATLRDFGVGK 142
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 143 RGI-EERIQE 151
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 56.8 bits (131), Expect = 6e-08
Identities = 33/130 (25%), Positives = 62/130 (47%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ H ++ S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSRGKLPPGPTPLPFIGNYLQLNTEHICDSIMKFSECYGPVFTIHLGPRRVVVLC 82
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H VR+A + FSGR + G G+ + G + + + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFEWVFKGYGVAFSNGERAKQLLRFAIATLRDFGVGK 142
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 143 RGI-EERIQE 151
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 56.4 bits (130), Expect = 8e-08
Identities = 33/130 (25%), Positives = 62/130 (47%), Gaps = 2/130 (1%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ H ++ S+ YG ++ + +G VVL
Sbjct: 23 VWQQRKSRGKLPPGPTPLPFIGNYLQLNTEHICDSIMKFSECYGPVFTIHLGPRRVVVLC 82
Query: 397 DHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGIICAEGGLWRDQRKLITSWLKSFGMSK 570
H VR+A + FSGR + G G+ + G + + + L+ FG+ K
Sbjct: 83 GHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVAFSNGERAKQLLRFAIATLRDFGVGK 142
Query: 571 HSVSREKLEK 600
+ E++++
Sbjct: 143 RGI-EERIQE 151
>L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein.
Length = 468
Score = 54.4 bits (125), Expect = 3e-07
Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 2/108 (1%)
Frame = +1
Query: 331 LSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICAE 504
LSK YG ++ L G VVL +++V++A + FSGR L G GI+ +
Sbjct: 35 LSKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSN 94
Query: 505 GGLWRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
G W++ R+ L++FGM K S+ E R+ ++E + KT
Sbjct: 95 GKRWKEIRRFSLMTLRNFGMGKRSI-----EDRVQEEARCLVEELRKT 137
>U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochrome
P450 protein.
Length = 543
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/138 (24%), Positives = 74/138 (53%), Gaps = 5/138 (3%)
Frame = +1
Query: 232 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 411
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 412 RDAFSK--DSFSGRAPLYLTHGLMNGNGIICAEGGL---WRDQRKLITSWLKSFGMSKHS 576
A + +F+ R P + + +++G G A G W+ QR+ S +++F ++
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG-GRSMAFGHYSEHWKVQRRAAHSMMRNF-FTRQP 160
Query: 577 VSREKLEKRIASGVYEIL 630
SR+ LE + S E++
Sbjct: 161 RSRQVLEGHVLSEARELV 178
>U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein.
Length = 543
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/138 (24%), Positives = 74/138 (53%), Gaps = 5/138 (3%)
Frame = +1
Query: 232 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 411
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 412 RDAFSK--DSFSGRAPLYLTHGLMNGNGIICAEGGL---WRDQRKLITSWLKSFGMSKHS 576
A + +F+ R P + + +++G G A G W+ QR+ S +++F ++
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG-GRSMAFGHYSEHWKVQRRAAHSMMRNF-FTRQP 160
Query: 577 VSREKLEKRIASGVYEIL 630
SR+ LE + S E++
Sbjct: 161 RSRQVLEGHVLSEARELV 178
>DQ359216-1|ABC95161.1| 347|Homo sapiens dioxin-inducible
cytochrome P450 protein.
Length = 347
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/138 (24%), Positives = 74/138 (53%), Gaps = 5/138 (3%)
Frame = +1
Query: 232 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 411
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 412 RDAFSK--DSFSGRAPLYLTHGLMNGNGIICAEGGL---WRDQRKLITSWLKSFGMSKHS 576
A + +F+ R P + + +++G G A G W+ QR+ S +++F ++
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG-GRSMAFGHYSEHWKVQRRAAHSMMRNF-FTRQP 160
Query: 577 VSREKLEKRIASGVYEIL 630
SR+ LE + S E++
Sbjct: 161 RSRQVLEGHVLSEARELV 178
>BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/138 (24%), Positives = 74/138 (53%), Gaps = 5/138 (3%)
Frame = +1
Query: 232 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 411
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 412 RDAFSK--DSFSGRAPLYLTHGLMNGNGIICAEGGL---WRDQRKLITSWLKSFGMSKHS 576
A + +F+ R P + + +++G G A G W+ QR+ S +++F ++
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG-GRSMAFGHYSEHWKVQRRAAHSMMRNF-FTRQP 160
Query: 577 VSREKLEKRIASGVYEIL 630
SR+ LE + S E++
Sbjct: 161 RSRQVLEGHVLSEARELV 178
>BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/138 (24%), Positives = 74/138 (53%), Gaps = 5/138 (3%)
Frame = +1
Query: 232 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 411
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 412 RDAFSK--DSFSGRAPLYLTHGLMNGNGIICAEGGL---WRDQRKLITSWLKSFGMSKHS 576
A + +F+ R P + + +++G G A G W+ QR+ S +++F ++
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG-GRSMAFGHYSEHWKVQRRAAHSMMRNF-FTRQP 160
Query: 577 VSREKLEKRIASGVYEIL 630
SR+ LE + S E++
Sbjct: 161 RSRQVLEGHVLSEARELV 178
>BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/138 (24%), Positives = 74/138 (53%), Gaps = 5/138 (3%)
Frame = +1
Query: 232 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 411
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 412 RDAFSK--DSFSGRAPLYLTHGLMNGNGIICAEGGL---WRDQRKLITSWLKSFGMSKHS 576
A + +F+ R P + + +++G G A G W+ QR+ S +++F ++
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG-GRSMAFGHYSEHWKVQRRAAHSMMRNF-FTRQP 160
Query: 577 VSREKLEKRIASGVYEIL 630
SR+ LE + S E++
Sbjct: 161 RSRQVLEGHVLSEARELV 178
>AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/138 (24%), Positives = 74/138 (53%), Gaps = 5/138 (3%)
Frame = +1
Query: 232 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 411
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 412 RDAFSK--DSFSGRAPLYLTHGLMNGNGIICAEGGL---WRDQRKLITSWLKSFGMSKHS 576
A + +F+ R P + + +++G G A G W+ QR+ S +++F ++
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG-GRSMAFGHYSEHWKVQRRAAHSMMRNF-FTRQP 160
Query: 577 VSREKLEKRIASGVYEIL 630
SR+ LE + S E++
Sbjct: 161 RSRQVLEGHVLSEARELV 178
>AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1
protein.
Length = 543
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/138 (24%), Positives = 74/138 (53%), Gaps = 5/138 (3%)
Frame = +1
Query: 232 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 411
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 412 RDAFSK--DSFSGRAPLYLTHGLMNGNGIICAEGGL---WRDQRKLITSWLKSFGMSKHS 576
A + +F+ R P + + +++G G A G W+ QR+ S +++F ++
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG-GRSMAFGHYSEHWKVQRRAAHSMMRNF-FTRQP 160
Query: 577 VSREKLEKRIASGVYEIL 630
SR+ LE + S E++
Sbjct: 161 RSRQVLEGHVLSEARELV 178
>AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein.
Length = 543
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/138 (24%), Positives = 74/138 (53%), Gaps = 5/138 (3%)
Frame = +1
Query: 232 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 411
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 412 RDAFSK--DSFSGRAPLYLTHGLMNGNGIICAEGGL---WRDQRKLITSWLKSFGMSKHS 576
A + +F+ R P + + +++G G A G W+ QR+ S +++F ++
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG-GRSMAFGHYSEHWKVQRRAAHSMMRNF-FTRQP 160
Query: 577 VSREKLEKRIASGVYEIL 630
SR+ LE + S E++
Sbjct: 161 RSRQVLEGHVLSEARELV 178
>X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein.
Length = 497
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6
protein.
Length = 497
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein.
Length = 497
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6
protein.
Length = 496
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6
protein.
Length = 497
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 51.6 bits (118), Expect = 2e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFNLQLAWTPVVVLNGLAAVREAMVT 93
Query: 430 --DSFSGR--APLYLTHGL-MNGNGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R AP+Y G G+I + G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 RGEDTADRPPAPIYQVLGFGPRSQGVILSRYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 51.2 bits (117), Expect = 3e-06
Identities = 35/118 (29%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSISTLRNLGLGKKSLEQ 151
>DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6
protein.
Length = 500
Score = 49.2 bits (112), Expect = 1e-05
Identities = 34/118 (28%), Positives = 57/118 (48%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ + L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPIIQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 49.2 bits (112), Expect = 1e-05
Identities = 34/118 (28%), Positives = 57/118 (48%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ + L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPIIQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 49.2 bits (112), Expect = 1e-05
Identities = 34/118 (28%), Positives = 57/118 (48%), Gaps = 6/118 (5%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK 429
PPGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 34 PPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVT 93
Query: 430 --DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ + L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 94 HGEDTADRPPVPIIQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/117 (29%), Positives = 57/117 (48%), Gaps = 6/117 (5%)
Frame = +1
Query: 253 PGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK- 429
PGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 35 PGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTH 94
Query: 430 -DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 95 GEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/117 (29%), Positives = 57/117 (48%), Gaps = 6/117 (5%)
Frame = +1
Query: 253 PGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK- 429
PGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 35 PGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTH 94
Query: 430 -DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 95 GEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/117 (29%), Positives = 57/117 (48%), Gaps = 6/117 (5%)
Frame = +1
Query: 253 PGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK- 429
PGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 35 PGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTH 94
Query: 430 -DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 95 GEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/117 (29%), Positives = 57/117 (48%), Gaps = 6/117 (5%)
Frame = +1
Query: 253 PGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK- 429
PGP LP +G L +D + L + +G ++ L++ VVL+ VR+A
Sbjct: 35 PGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTH 94
Query: 430 -DSFSGRAPLYLTHGLMNG---NGIICAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
+ + R P+ +T L G G+ A G WR+QR+ S L++ G+ K S+ +
Sbjct: 95 GEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 151
>X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd
base in codon) protein.
Length = 448
Score = 46.0 bits (104), Expect = 1e-04
Identities = 25/96 (26%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
Frame = +1
Query: 319 TLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF--SKDSFSGRAPLYLTHGLMNGNGI 492
+L +S+ YG ++ + +G VVL H VR+A + FSGR + G G+
Sbjct: 11 SLMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGV 70
Query: 493 ICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
+ + G + R+ + L+ FG+ K + E++++
Sbjct: 71 VFSNGERAKQLRRFSIATLRDFGVGKRGI-EERIQE 105
>AY513607-1|AAR90938.1| 100|Homo sapiens truncated cytochrome P450
2A13 variant 4 protein.
Length = 100
Score = 44.4 bits (100), Expect = 4e-04
Identities = 23/78 (29%), Positives = 41/78 (52%), Gaps = 2/78 (2%)
Frame = +1
Query: 217 IFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLS 396
++++ K LPPGP LP +G ++ + +L +S+ YG ++ + +G VVL
Sbjct: 23 VWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLC 82
Query: 397 DHKLVRDAF--SKDSFSG 444
H V++A + FSG
Sbjct: 83 GHDAVKEALVDQAEEFSG 100
>AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens
cDNA FLJ20359 fis, clone HEP16626. ).
Length = 408
Score = 44.4 bits (100), Expect = 4e-04
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Frame = +1
Query: 331 LSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNGNGIICAE 504
LS+ YG ++ + +G VVL+ + V++A + + R P+ + + G GI +
Sbjct: 3 LSERYGPVFTVHLGRQKTVVLTGFEAVKEALAGPGQELADRPPIAIFQLIQRGGGIFFSS 62
Query: 505 GGLWRDQRKLITSWLKSFGMSKHSVSREKLEK 600
G WR R+ L S G+ + V+ + L++
Sbjct: 63 GARWRAARQFTVRALHSLGVGREPVADKILQE 94
>DQ372705-1|ABD16216.1| 150|Homo sapiens mutant cytochrome p450
protein.
Length = 150
Score = 42.3 bits (95), Expect = 0.001
Identities = 20/86 (23%), Positives = 49/86 (56%), Gaps = 2/86 (2%)
Frame = +1
Query: 232 KEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLV 411
++ ++ PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + +
Sbjct: 45 RQLRSAPPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAI 103
Query: 412 RDAFSK--DSFSGRAPLYLTHGLMNG 483
A + +F+ R P + + +++G
Sbjct: 104 HQALVQQGSAFADR-PAFASFRVVSG 128
>AF171066-1|AAG43404.1| 112|Homo sapiens CYP1B1 variant protein.
Length = 112
Score = 40.3 bits (90), Expect = 0.006
Identities = 16/57 (28%), Positives = 33/57 (57%)
Frame = +1
Query: 250 PPGPWGLPIVGYLPFIDRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDA 420
PPGP+ P++G + + H++ L++ YG ++ +++GS VVL+ + + A
Sbjct: 51 PPGPFAWPLIGNAAAVGQA-AHLSFARLARRYGDVFQIRLGSCPIVVLNGERAIHQA 106
>AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxylase
mutant allele variant protein.
Length = 566
Score = 37.5 bits (83), Expect = 0.041
Identities = 26/91 (28%), Positives = 46/91 (50%), Gaps = 6/91 (6%)
Frame = +1
Query: 331 LSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSK--DSFSGRAPLYLTHGLMNG---NGII 495
L + +G ++ L++ VVL+ VR+A + + R P+ +T L G G+
Sbjct: 131 LRRRFGDVFSLQLAWTPVVVLNGLAAVREAMVTRGEDTADRPPVPITQILGFGPRSQGVF 190
Query: 496 CAE-GGLWRDQRKLITSWLKSFGMSKHSVSR 585
A G WR+QR+ S L++ G+ K S+ +
Sbjct: 191 LARYGPAWREQRRFSVSTLRNLGLGKKSLEQ 221
>BC012027-1|AAH12027.1| 168|Homo sapiens CYP2U1 protein protein.
Length = 168
Score = 35.1 bits (77), Expect = 0.22
Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 2/48 (4%)
Frame = +1
Query: 310 PHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDAFSKDS--FSGR 447
P + L +L++ YG+I+ +G VVLSD VR+A + + FS R
Sbjct: 103 PQVLLAHLARVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDR 150
>M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein.
Length = 383
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/56 (30%), Positives = 29/56 (51%)
Frame = +1
Query: 481 GNGIICAEGGLWRDQRKLITSWLKSFGMSKHSVSREKLEKRIASGVYEILENIEKT 648
G GI+ + G W++ R+ L++FGM K S+ E R+ ++E + KT
Sbjct: 2 GFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSI-----EDRVQEEARCLVEELRKT 52
>BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 31.5 bits (68), Expect = 2.7
Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Frame = +1
Query: 253 PGPWGLPIVGYLPFI----DRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDA 420
PGP P++G L I H TL K YG I+ +K+GS +V L L+
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEAL 118
Query: 421 FSKDS 435
+ +S
Sbjct: 119 YRTES 123
>BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 31.5 bits (68), Expect = 2.7
Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Frame = +1
Query: 253 PGPWGLPIVGYLPFI----DRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDA 420
PGP P++G L I H TL K YG I+ +K+GS +V L L+
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEAL 118
Query: 421 FSKDS 435
+ +S
Sbjct: 119 YRTES 123
>AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 448
Score = 31.5 bits (68), Expect = 2.7
Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Frame = +1
Query: 253 PGPWGLPIVGYLPFI----DRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDA 420
PGP P++G L I H TL K YG I+ +K+GS +V L L+
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEAL 118
Query: 421 FSKDS 435
+ +S
Sbjct: 119 YRTES 123
>AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 31.5 bits (68), Expect = 2.7
Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Frame = +1
Query: 253 PGPWGLPIVGYLPFI----DRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDA 420
PGP P++G L I H TL K YG I+ +K+GS +V L L+
Sbjct: 59 PGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEAL 118
Query: 421 FSKDS 435
+ +S
Sbjct: 119 YRTES 123
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 31.1 bits (67), Expect = 3.6
Identities = 27/100 (27%), Positives = 41/100 (41%), Gaps = 8/100 (8%)
Frame = +1
Query: 253 PGPWGLPIVGYLPFI----DRYHPHITLTNLSKTYGAIYGLKMGSIYAVVLSDHKLVRDA 420
PGP P++ L I H TL K YG I+ +K+GS +V L L+
Sbjct: 59 PGPTSWPLLASLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEAL 118
Query: 421 FSKDSFSGRAPLYLTHGLMN----GNGIICAEGGLWRDQR 528
+ +S R + + G G++ EG W+ R
Sbjct: 119 YRTESVPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVR 158
>BC036233-1|AAH36233.1| 946|Homo sapiens WDR66 protein protein.
Length = 946
Score = 31.1 bits (67), Expect = 3.6
Identities = 10/23 (43%), Positives = 17/23 (73%), Gaps = 2/23 (8%)
Frame = -1
Query: 527 LWSLHKPPS--AQIIPFPFIRPC 465
+W +H+PPS + + FP+I+PC
Sbjct: 477 VWDIHRPPSSASTFLGFPYIKPC 499
>BC028421-1|AAH28421.1| 1154|Homo sapiens WD repeat domain 66
protein.
Length = 1154
Score = 31.1 bits (67), Expect = 3.6
Identities = 10/23 (43%), Positives = 17/23 (73%), Gaps = 2/23 (8%)
Frame = -1
Query: 527 LWSLHKPPS--AQIIPFPFIRPC 465
+W +H+PPS + + FP+I+PC
Sbjct: 477 VWDIHRPPSSASTFLGFPYIKPC 499
>EF122245-1|ABO41980.1| 54|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 54
Score = 30.7 bits (66), Expect = 4.7
Identities = 16/40 (40%), Positives = 25/40 (62%), Gaps = 2/40 (5%)
Frame = +1
Query: 331 LSKTYGAIYGLKMGSIYAVVLSDHKLVRDAF--SKDSFSG 444
LSK YG++Y + +G VVLS ++ V++A + FSG
Sbjct: 1 LSKEYGSMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSG 40
>X58908-1|CAA41711.1| 97|Homo sapiens steroid 21-monooxygenase
protein.
Length = 97
Score = 30.3 bits (65), Expect = 6.3
Identities = 28/96 (29%), Positives = 45/96 (46%), Gaps = 5/96 (5%)
Frame = +1
Query: 175 LYFIWLVTFVAG---FWIFKKIKEWQNLPPGPWGLPIVGYLPFIDRYHPHITLTNLSKTY 345
L + L+ +AG W + K++ LP P G+L + P I L L++ +
Sbjct: 4 LGLLLLLPLLAGARLLWNWWKLRSLHLLPLAP------GFLHLLQPDLP-IYLLGLTQKF 56
Query: 346 GAIYGLKMGSIYAVVLSDHKLVRDAFSKD--SFSGR 447
G IY L +G VVL+ + + +A K F+GR
Sbjct: 57 GPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGR 92
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 103,653,995
Number of Sequences: 237096
Number of extensions: 2466906
Number of successful extensions: 8006
Number of sequences better than 10.0: 181
Number of HSP's better than 10.0 without gapping: 7696
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7871
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7310122300
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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