Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fprWP12_F_L13
(651 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC038857-1|AAH38857.1| 559|Homo sapiens microtubule-associated ... 104 2e-22
U89330-1|AAB48098.1| 1824|Homo sapiens microtubule-associated pr... 101 3e-21
U89329-1|AAB48097.1| 472|Homo sapiens microtubule-associated pr... 101 3e-21
BC117123-1|AAI17124.1| 471|Homo sapiens microtubule-associated ... 100 4e-21
BC110423-1|AAI10424.1| 471|Homo sapiens microtubule-associated ... 100 4e-21
AB209330-1|BAD92567.1| 472|Homo sapiens microtubule-associated ... 100 4e-21
X14474-1|CAA32636.1| 383|Homo sapiens protein ( Human mRNA for ... 99 7e-21
BC114948-1|AAI14949.1| 383|Homo sapiens microtubule-associated ... 99 7e-21
AY730549-1|AAU45390.1| 412|Homo sapiens microtubule-associated ... 99 7e-21
AF047863-2|AAC04279.1| 441|Homo sapiens CNS specific microtubul... 99 7e-21
AF047863-1|AAC04277.1| 758|Homo sapiens PNS specific microtubul... 99 7e-21
U01828-1|AAA03354.1| 1826|Homo sapiens microtubule-associated pr... 99 2e-20
AY526356-1|AAS17881.1| 244|Homo sapiens microtubule-associated ... 98 2e-20
J03778-1|AAA60615.1| 352|Homo sapiens MTBT1 protein. 98 3e-20
BT006772-1|AAP35418.1| 352|Homo sapiens microtubule-associated ... 98 3e-20
BC114504-1|AAI14505.1| 352|Homo sapiens microtubule-associated ... 98 3e-20
BC101936-1|AAI01937.1| 352|Homo sapiens microtubule-associated ... 98 3e-20
BC099721-1|AAH99721.1| 352|Homo sapiens microtubule-associated ... 98 3e-20
BC098281-1|AAH98281.1| 352|Homo sapiens microtubule-associated ... 98 3e-20
BC000558-1|AAH00558.1| 352|Homo sapiens microtubule-associated ... 98 3e-20
AF047863-3|AAC04278.1| 352|Homo sapiens CNS specific microtubul... 98 3e-20
S76756-1|AAB33379.1| 125|Homo sapiens microtubule-associated pr... 94 3e-19
AB209377-1|BAD92614.1| 1163|Homo sapiens microtubule-associated ... 83 1e-15
U19727-1|AAA67361.1| 1152|Homo sapiens microtubule-associated pr... 75 3e-13
M64571-1|AAA59553.1| 1152|Homo sapiens microtubule-associated pr... 75 3e-13
BC048200-1|AAH48200.1| 857|Homo sapiens MAP4 protein protein. 75 3e-13
BC015149-1|AAH15149.1| 979|Homo sapiens MAP4 protein protein. 75 3e-13
BC012794-1|AAH12794.1| 979|Homo sapiens MAP4 protein protein. 75 3e-13
BC008715-1|AAH08715.1| 979|Homo sapiens MAP4 protein protein. 75 3e-13
AL831878-1|CAD38562.1| 187|Homo sapiens hypothetical protein pr... 71 4e-12
BC024302-1|AAH24302.1| 339|Homo sapiens Unknown (protein for IM... 52 1e-06
AK022730-1|BAB14209.1| 293|Homo sapiens protein ( Homo sapiens ... 30 6.2
AJ415330-1|CAC94399.1| 87|Homo sapiens immunoglobulin heavy ch... 30 8.2
>BC038857-1|AAH38857.1| 559|Homo sapiens microtubule-associated
protein 2 protein.
Length = 559
Score = 104 bits (250), Expect = 2e-22
Identities = 56/125 (44%), Positives = 81/125 (64%), Gaps = 2/125 (1%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K I TP + P ++++ N P P+LK VKSKIGS DN Y+P GG+V+I N+K++F
Sbjct: 344 KVAIIRTPPKSPATP-KQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVRILNKKIDF 402
Query: 461 GNITPKIAAK-NEAYTPSGGAKKIVTNKLEW-NAKSKVGSLQNASYKPGGGDKKIETVKL 634
+ + +K N ++ GG +IVT K++ + SK GSL+N ++PGGG KIE+VKL
Sbjct: 403 SKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKL 462
Query: 635 DFGEK 649
DF EK
Sbjct: 463 DFKEK 467
Score = 79.0 bits (186), Expect = 1e-14
Identities = 41/94 (43%), Positives = 62/94 (65%), Gaps = 3/94 (3%)
Frame = +2
Query: 374 VKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAA-KNEAYTPSGGAKKIVTNKLEW 550
V+S+ GS DN + GGG V+I +K++ ++T K + KN + P GG KI + KL++
Sbjct: 405 VQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDF 464
Query: 551 N--AKSKVGSLQNASYKPGGGDKKIETVKLDFGE 646
A++KVGSL NA + PGGG+ KI++ KL+F E
Sbjct: 465 KEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFRE 498
Score = 43.6 bits (98), Expect = 6e-04
Identities = 25/68 (36%), Positives = 39/68 (57%), Gaps = 1/68 (1%)
Frame = +2
Query: 377 KSKIGSLDNATYKPGGGKVKIENRKLEF-GNITPKIAAKNEAYTPSGGAKKIVTNKLEWN 553
++K+GSLDNA + PGGG VKI+++KL F + ++ E T S G + + + N
Sbjct: 469 QAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSN 528
Query: 554 AKSKVGSL 577
S GS+
Sbjct: 529 VSSS-GSI 535
>U89330-1|AAB48098.1| 1824|Homo sapiens microtubule-associated protein
2 protein.
Length = 1824
Score = 101 bits (241), Expect = 3e-21
Identities = 54/125 (43%), Positives = 81/125 (64%), Gaps = 3/125 (2%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K I TP + + ++++ N P P+LK VKSKIGS DN Y+P GG+V+I +K++
Sbjct: 1639 KVAIIRTPPKSPGLTPKQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDL 1698
Query: 461 GNITPKIAA-KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIETVK 631
++T K + KN + P GG KI + KL++ A++KVGSL NA + PGGG+ KI++ K
Sbjct: 1699 SHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQK 1758
Query: 632 LDFGE 646
L+F E
Sbjct: 1759 LNFRE 1763
Score = 63.3 bits (147), Expect = 7e-10
Identities = 44/130 (33%), Positives = 67/130 (51%), Gaps = 5/130 (3%)
Frame = +2
Query: 275 TAKTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPG--GGKVKIENR 448
+++TP P + P G S L + K+ + PG ++++ N+
Sbjct: 1606 SSRTPGTPGTPSYPRTPHTP---GTPKSAILVPSEKKVAIIRTPPKSPGLTPKQLRLINQ 1662
Query: 449 KL-EFGNITPKIAAK-NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKI 619
L + N+ KI + N Y P GG +IVT K++ + SK GSL+N ++PGGG KI
Sbjct: 1663 PLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKI 1722
Query: 620 ETVKLDFGEK 649
E+VKLDF EK
Sbjct: 1723 ESVKLDFKEK 1732
>U89329-1|AAB48097.1| 472|Homo sapiens microtubule-associated
protein 2C protein.
Length = 472
Score = 101 bits (241), Expect = 3e-21
Identities = 54/125 (43%), Positives = 81/125 (64%), Gaps = 3/125 (2%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K I TP + + ++++ N P P+LK VKSKIGS DN Y+P GG+V+I +K++
Sbjct: 287 KVAIIRTPPKSPGLTPKQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDL 346
Query: 461 GNITPKIAA-KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIETVK 631
++T K + KN + P GG KI + KL++ A++KVGSL NA + PGGG+ KI++ K
Sbjct: 347 SHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQK 406
Query: 632 LDFGE 646
L+F E
Sbjct: 407 LNFRE 411
Score = 63.3 bits (147), Expect = 7e-10
Identities = 44/130 (33%), Positives = 67/130 (51%), Gaps = 5/130 (3%)
Frame = +2
Query: 275 TAKTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPG--GGKVKIENR 448
+++TP P + P G S L + K+ + PG ++++ N+
Sbjct: 254 SSRTPGTPGTPSYPRTPHTP---GTPKSAILVPSEKKVAIIRTPPKSPGLTPKQLRLINQ 310
Query: 449 KL-EFGNITPKIAAK-NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKI 619
L + N+ KI + N Y P GG +IVT K++ + SK GSL+N ++PGGG KI
Sbjct: 311 PLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKI 370
Query: 620 ETVKLDFGEK 649
E+VKLDF EK
Sbjct: 371 ESVKLDFKEK 380
>BC117123-1|AAI17124.1| 471|Homo sapiens microtubule-associated
protein 2 protein.
Length = 471
Score = 100 bits (240), Expect = 4e-21
Identities = 55/125 (44%), Positives = 81/125 (64%), Gaps = 3/125 (2%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K I TP + P ++++ N P P+LK VKSKIGS DN Y+P GG+V+I +K++
Sbjct: 287 KVAIIRTPPKSPATP-KQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDL 345
Query: 461 GNITPKIAA-KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIETVK 631
++T K + KN + P GG KI + KL++ A++KVGSL NA + PGGG+ KI++ K
Sbjct: 346 SHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQK 405
Query: 632 LDFGE 646
L+F E
Sbjct: 406 LNFRE 410
Score = 63.3 bits (147), Expect = 7e-10
Identities = 44/129 (34%), Positives = 66/129 (51%), Gaps = 4/129 (3%)
Frame = +2
Query: 275 TAKTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGK-VKIENRK 451
+++TP P + P G S L + K+ + P K +++ N+
Sbjct: 254 SSRTPGTPGTPSYPRTPHTP---GTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQP 310
Query: 452 L-EFGNITPKIAAK-NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIE 622
L + N+ KI + N Y P GG +IVT K++ + SK GSL+N ++PGGG KIE
Sbjct: 311 LPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIE 370
Query: 623 TVKLDFGEK 649
+VKLDF EK
Sbjct: 371 SVKLDFKEK 379
>BC110423-1|AAI10424.1| 471|Homo sapiens microtubule-associated
protein 2 protein.
Length = 471
Score = 100 bits (240), Expect = 4e-21
Identities = 55/125 (44%), Positives = 81/125 (64%), Gaps = 3/125 (2%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K I TP + P ++++ N P P+LK VKSKIGS DN Y+P GG+V+I +K++
Sbjct: 287 KVAIIRTPPKSPATP-KQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDL 345
Query: 461 GNITPKIAA-KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIETVK 631
++T K + KN + P GG KI + KL++ A++KVGSL NA + PGGG+ KI++ K
Sbjct: 346 SHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQK 405
Query: 632 LDFGE 646
L+F E
Sbjct: 406 LNFRE 410
Score = 63.3 bits (147), Expect = 7e-10
Identities = 44/129 (34%), Positives = 66/129 (51%), Gaps = 4/129 (3%)
Frame = +2
Query: 275 TAKTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGK-VKIENRK 451
+++TP P + P G S L + K+ + P K +++ N+
Sbjct: 254 SSRTPGTPGTPSYPRTPHTP---GTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQP 310
Query: 452 L-EFGNITPKIAAK-NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIE 622
L + N+ KI + N Y P GG +IVT K++ + SK GSL+N ++PGGG KIE
Sbjct: 311 LPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIE 370
Query: 623 TVKLDFGEK 649
+VKLDF EK
Sbjct: 371 SVKLDFKEK 379
>AB209330-1|BAD92567.1| 472|Homo sapiens microtubule-associated
protein 2 isoform 2 variant protein.
Length = 472
Score = 100 bits (240), Expect = 4e-21
Identities = 55/125 (44%), Positives = 81/125 (64%), Gaps = 3/125 (2%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K I TP + P ++++ N P P+LK VKSKIGS DN Y+P GG+V+I +K++
Sbjct: 288 KVAIIRTPPKSPATP-KQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDL 346
Query: 461 GNITPKIAA-KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIETVK 631
++T K + KN + P GG KI + KL++ A++KVGSL NA + PGGG+ KI++ K
Sbjct: 347 SHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQK 406
Query: 632 LDFGE 646
L+F E
Sbjct: 407 LNFRE 411
Score = 63.3 bits (147), Expect = 7e-10
Identities = 44/129 (34%), Positives = 66/129 (51%), Gaps = 4/129 (3%)
Frame = +2
Query: 275 TAKTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGK-VKIENRK 451
+++TP P + P G S L + K+ + P K +++ N+
Sbjct: 255 SSRTPGTPGTPSYPRTPHTP---GTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQP 311
Query: 452 L-EFGNITPKIAAK-NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIE 622
L + N+ KI + N Y P GG +IVT K++ + SK GSL+N ++PGGG KIE
Sbjct: 312 LPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIE 371
Query: 623 TVKLDFGEK 649
+VKLDF EK
Sbjct: 372 SVKLDFKEK 380
>X14474-1|CAA32636.1| 383|Homo sapiens protein ( Human mRNA for
microtubule-associated tau protein. ).
Length = 383
Score = 99 bits (238), Expect = 7e-21
Identities = 50/125 (40%), Positives = 77/125 (61%), Gaps = 2/125 (1%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K + TP + +++Q P P+LK VKSKIGS +N ++PGGGKV+I N+KL+
Sbjct: 167 KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDL 226
Query: 461 GNITPKIAAK-NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKL 634
N+ K +K N + P GG+ +IV ++ + SK GSL N +KPGGG ++++ KL
Sbjct: 227 SNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKL 286
Query: 635 DFGEK 649
DF ++
Sbjct: 287 DFKDR 291
Score = 79.8 bits (188), Expect = 8e-15
Identities = 45/108 (41%), Positives = 66/108 (61%), Gaps = 3/108 (2%)
Frame = +2
Query: 332 KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK-NEAYTP 508
KVQ+ N +L V+SK GS DN + PGGG V+I + ++ +T K + N + P
Sbjct: 216 KVQIINKKL-DLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP 274
Query: 509 SGGAKKIVTNKLEWN--AKSKVGSLQNASYKPGGGDKKIETVKLDFGE 646
GG ++ + KL++ +SK+GSL N ++ PGGG+KKIET KL F E
Sbjct: 275 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRE 322
Score = 59.7 bits (138), Expect = 9e-09
Identities = 41/99 (41%), Positives = 57/99 (57%), Gaps = 5/99 (5%)
Frame = +2
Query: 314 KKVPMN-KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGN-ITPKIAA 487
K VP VQ+ P +L V SK GSL N +KPGGG+V++++ KL+F + + KI +
Sbjct: 240 KHVPGGGSVQIVYKPV-DLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGS 298
Query: 488 -KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYK 595
N + P GG KKI T+KL + NAK+K YK
Sbjct: 299 LDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYK 337
>BC114948-1|AAI14949.1| 383|Homo sapiens microtubule-associated
protein tau protein.
Length = 383
Score = 99 bits (238), Expect = 7e-21
Identities = 50/125 (40%), Positives = 77/125 (61%), Gaps = 2/125 (1%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K + TP + +++Q P P+LK VKSKIGS +N ++PGGGKV+I N+KL+
Sbjct: 167 KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDL 226
Query: 461 GNITPKIAAK-NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKL 634
N+ K +K N + P GG+ +IV ++ + SK GSL N +KPGGG ++++ KL
Sbjct: 227 SNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKL 286
Query: 635 DFGEK 649
DF ++
Sbjct: 287 DFKDR 291
Score = 79.8 bits (188), Expect = 8e-15
Identities = 45/108 (41%), Positives = 66/108 (61%), Gaps = 3/108 (2%)
Frame = +2
Query: 332 KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK-NEAYTP 508
KVQ+ N +L V+SK GS DN + PGGG V+I + ++ +T K + N + P
Sbjct: 216 KVQIINKKL-DLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP 274
Query: 509 SGGAKKIVTNKLEWN--AKSKVGSLQNASYKPGGGDKKIETVKLDFGE 646
GG ++ + KL++ +SK+GSL N ++ PGGG+KKIET KL F E
Sbjct: 275 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRE 322
Score = 59.7 bits (138), Expect = 9e-09
Identities = 41/99 (41%), Positives = 57/99 (57%), Gaps = 5/99 (5%)
Frame = +2
Query: 314 KKVPMN-KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGN-ITPKIAA 487
K VP VQ+ P +L V SK GSL N +KPGGG+V++++ KL+F + + KI +
Sbjct: 240 KHVPGGGSVQIVYKPV-DLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGS 298
Query: 488 -KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYK 595
N + P GG KKI T+KL + NAK+K YK
Sbjct: 299 LDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYK 337
>AY730549-1|AAU45390.1| 412|Homo sapiens microtubule-associated tau
protein protein.
Length = 412
Score = 99 bits (238), Expect = 7e-21
Identities = 50/125 (40%), Positives = 77/125 (61%), Gaps = 2/125 (1%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K + TP + +++Q P P+LK VKSKIGS +N ++PGGGKV+I N+KL+
Sbjct: 196 KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDL 255
Query: 461 GNITPKIAAK-NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKL 634
N+ K +K N + P GG+ +IV ++ + SK GSL N +KPGGG ++++ KL
Sbjct: 256 SNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKL 315
Query: 635 DFGEK 649
DF ++
Sbjct: 316 DFKDR 320
Score = 79.8 bits (188), Expect = 8e-15
Identities = 45/108 (41%), Positives = 66/108 (61%), Gaps = 3/108 (2%)
Frame = +2
Query: 332 KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK-NEAYTP 508
KVQ+ N +L V+SK GS DN + PGGG V+I + ++ +T K + N + P
Sbjct: 245 KVQIINKKL-DLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP 303
Query: 509 SGGAKKIVTNKLEWN--AKSKVGSLQNASYKPGGGDKKIETVKLDFGE 646
GG ++ + KL++ +SK+GSL N ++ PGGG+KKIET KL F E
Sbjct: 304 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRE 351
Score = 59.7 bits (138), Expect = 9e-09
Identities = 41/99 (41%), Positives = 57/99 (57%), Gaps = 5/99 (5%)
Frame = +2
Query: 314 KKVPMN-KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGN-ITPKIAA 487
K VP VQ+ P +L V SK GSL N +KPGGG+V++++ KL+F + + KI +
Sbjct: 269 KHVPGGGSVQIVYKPV-DLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGS 327
Query: 488 -KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYK 595
N + P GG KKI T+KL + NAK+K YK
Sbjct: 328 LDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYK 366
>AF047863-2|AAC04279.1| 441|Homo sapiens CNS specific
microtubule-associated protein tau, adult isoform
protein.
Length = 441
Score = 99 bits (238), Expect = 7e-21
Identities = 50/125 (40%), Positives = 77/125 (61%), Gaps = 2/125 (1%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K + TP + +++Q P P+LK VKSKIGS +N ++PGGGKV+I N+KL+
Sbjct: 225 KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDL 284
Query: 461 GNITPKIAAK-NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKL 634
N+ K +K N + P GG+ +IV ++ + SK GSL N +KPGGG ++++ KL
Sbjct: 285 SNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKL 344
Query: 635 DFGEK 649
DF ++
Sbjct: 345 DFKDR 349
Score = 79.8 bits (188), Expect = 8e-15
Identities = 45/108 (41%), Positives = 66/108 (61%), Gaps = 3/108 (2%)
Frame = +2
Query: 332 KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK-NEAYTP 508
KVQ+ N +L V+SK GS DN + PGGG V+I + ++ +T K + N + P
Sbjct: 274 KVQIINKKL-DLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP 332
Query: 509 SGGAKKIVTNKLEWN--AKSKVGSLQNASYKPGGGDKKIETVKLDFGE 646
GG ++ + KL++ +SK+GSL N ++ PGGG+KKIET KL F E
Sbjct: 333 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRE 380
Score = 59.7 bits (138), Expect = 9e-09
Identities = 41/99 (41%), Positives = 57/99 (57%), Gaps = 5/99 (5%)
Frame = +2
Query: 314 KKVPMN-KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGN-ITPKIAA 487
K VP VQ+ P +L V SK GSL N +KPGGG+V++++ KL+F + + KI +
Sbjct: 298 KHVPGGGSVQIVYKPV-DLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGS 356
Query: 488 -KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYK 595
N + P GG KKI T+KL + NAK+K YK
Sbjct: 357 LDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYK 395
>AF047863-1|AAC04277.1| 758|Homo sapiens PNS specific
microtubule-associated protein tau, adult isoform
protein.
Length = 758
Score = 99 bits (238), Expect = 7e-21
Identities = 50/125 (40%), Positives = 77/125 (61%), Gaps = 2/125 (1%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K + TP + +++Q P P+LK VKSKIGS +N ++PGGGKV+I N+KL+
Sbjct: 542 KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDL 601
Query: 461 GNITPKIAAK-NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKL 634
N+ K +K N + P GG+ +IV ++ + SK GSL N +KPGGG ++++ KL
Sbjct: 602 SNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKL 661
Query: 635 DFGEK 649
DF ++
Sbjct: 662 DFKDR 666
Score = 79.8 bits (188), Expect = 8e-15
Identities = 45/108 (41%), Positives = 66/108 (61%), Gaps = 3/108 (2%)
Frame = +2
Query: 332 KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK-NEAYTP 508
KVQ+ N +L V+SK GS DN + PGGG V+I + ++ +T K + N + P
Sbjct: 591 KVQIINKKL-DLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP 649
Query: 509 SGGAKKIVTNKLEWN--AKSKVGSLQNASYKPGGGDKKIETVKLDFGE 646
GG ++ + KL++ +SK+GSL N ++ PGGG+KKIET KL F E
Sbjct: 650 GGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRE 697
Score = 59.7 bits (138), Expect = 9e-09
Identities = 41/99 (41%), Positives = 57/99 (57%), Gaps = 5/99 (5%)
Frame = +2
Query: 314 KKVPMN-KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGN-ITPKIAA 487
K VP VQ+ P +L V SK GSL N +KPGGG+V++++ KL+F + + KI +
Sbjct: 615 KHVPGGGSVQIVYKPV-DLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGS 673
Query: 488 -KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYK 595
N + P GG KKI T+KL + NAK+K YK
Sbjct: 674 LDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYK 712
>U01828-1|AAA03354.1| 1826|Homo sapiens microtubule-associated protein
2 protein.
Length = 1826
Score = 98.7 bits (235), Expect = 2e-20
Identities = 53/124 (42%), Positives = 77/124 (62%), Gaps = 2/124 (1%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K I TP + P ++++ N P P+LK VKSKIGS DN Y+P GG+V+I +K++
Sbjct: 1643 KVAIIRTPPKSPATP-KQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDL 1701
Query: 461 GNITPKIAAKNEAYTPSGGAKKIVTNKLEWNAK--SKVGSLQNASYKPGGGDKKIETVKL 634
++T K + P GG KI + KL++ K +KVGSL NA + PGGG+ KI++ KL
Sbjct: 1702 SHVTSKCGSLKNIDRPGGGRVKIESVKLDFKEKVQAKVGSLDNAHHVPGGGNVKIDSQKL 1761
Query: 635 DFGE 646
+F E
Sbjct: 1762 NFRE 1765
Score = 58.4 bits (135), Expect = 2e-08
Identities = 44/129 (34%), Positives = 65/129 (50%), Gaps = 4/129 (3%)
Frame = +2
Query: 275 TAKTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGK-VKIENRK 451
+++TP P + P G S L + K+ + P K +++ N+
Sbjct: 1610 SSRTPGTPGTPSYPRTPHTP---GTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQP 1666
Query: 452 L-EFGNITPKIAAK-NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIE 622
L + N+ KI + N Y P GG +IVT K++ + SK GSL+N +PGGG KIE
Sbjct: 1667 LPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNID-RPGGGRVKIE 1725
Query: 623 TVKLDFGEK 649
+VKLDF EK
Sbjct: 1726 SVKLDFKEK 1734
>AY526356-1|AAS17881.1| 244|Homo sapiens microtubule-associated
protein tau protein.
Length = 244
Score = 98.3 bits (234), Expect = 2e-20
Identities = 50/125 (40%), Positives = 76/125 (60%), Gaps = 3/125 (2%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K + TP + M+++Q P P+LK VKSKIGS +N ++PGGG V+I + ++
Sbjct: 77 KVAVVRTPPKSPSSAMSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGSVQIVYKPVDL 136
Query: 461 GNITPKIAA-KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIETVK 631
+T K + N + P GG ++ + KL++ +SK+GSL N ++ PGGG+KKIET K
Sbjct: 137 SKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHK 196
Query: 632 LDFGE 646
L F E
Sbjct: 197 LTFRE 201
Score = 59.3 bits (137), Expect = 1e-08
Identities = 35/82 (42%), Positives = 50/82 (60%), Gaps = 4/82 (4%)
Frame = +2
Query: 362 NLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGN-ITPKIAA-KNEAYTPSGGAKKIVT 535
+L V SK GSL N +KPGGG+V++++ KL+F + + KI + N + P GG KKI T
Sbjct: 135 DLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIET 194
Query: 536 NKLEW--NAKSKVGSLQNASYK 595
+KL + NAK+K YK
Sbjct: 195 HKLTFRENAKAKTDHGAEIVYK 216
Score = 48.0 bits (109), Expect = 3e-05
Identities = 30/114 (26%), Positives = 59/114 (51%), Gaps = 5/114 (4%)
Frame = +2
Query: 323 PMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKL---EFGNITPKIAA-K 490
P ++ + + P+P + K K+ + P +++ + + N+ KI + +
Sbjct: 58 PGSRSRTPSLPTPPTREPK-KVAVVRTPPKSPSSAMSRLQTAPVPMPDLKNVKSKIGSTE 116
Query: 491 NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKLDFGEK 649
N + P GG+ +IV ++ + SK GSL N +KPGGG ++++ KLDF ++
Sbjct: 117 NLKHQPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDR 170
>J03778-1|AAA60615.1| 352|Homo sapiens MTBT1 protein.
Length = 352
Score = 97.9 bits (233), Expect = 3e-20
Identities = 50/125 (40%), Positives = 76/125 (60%), Gaps = 3/125 (2%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K + TP + +++Q P P+LK VKSKIGS +N ++PGGGKV+I + ++
Sbjct: 167 KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIVYKPVDL 226
Query: 461 GNITPKIAA-KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIETVK 631
+T K + N + P GG ++ + KL++ +SK+GSL N ++ PGGG+KKIET K
Sbjct: 227 SKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHK 286
Query: 632 LDFGE 646
L F E
Sbjct: 287 LTFRE 291
Score = 61.3 bits (142), Expect = 3e-09
Identities = 39/92 (42%), Positives = 55/92 (59%), Gaps = 4/92 (4%)
Frame = +2
Query: 332 KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGN-ITPKIAA-KNEAYT 505
KVQ+ P +L V SK GSL N +KPGGG+V++++ KL+F + + KI + N +
Sbjct: 216 KVQIVYKPV-DLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHV 274
Query: 506 PSGGAKKIVTNKLEW--NAKSKVGSLQNASYK 595
P GG KKI T+KL + NAK+K YK
Sbjct: 275 PGGGNKKIETHKLTFRENAKAKTDHGAEIVYK 306
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/114 (27%), Positives = 59/114 (51%), Gaps = 5/114 (4%)
Frame = +2
Query: 323 PMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKL---EFGNITPKIAA-K 490
P ++ + + P+P + K K+ + P K +++ + + N+ KI + +
Sbjct: 148 PGSRSRTPSLPTPPTREPK-KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTE 206
Query: 491 NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKLDFGEK 649
N + P GG +IV ++ + SK GSL N +KPGGG ++++ KLDF ++
Sbjct: 207 NLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDR 260
>BT006772-1|AAP35418.1| 352|Homo sapiens microtubule-associated
protein tau protein.
Length = 352
Score = 97.9 bits (233), Expect = 3e-20
Identities = 50/125 (40%), Positives = 76/125 (60%), Gaps = 3/125 (2%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K + TP + +++Q P P+LK VKSKIGS +N ++PGGGKV+I + ++
Sbjct: 167 KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIVYKPVDL 226
Query: 461 GNITPKIAA-KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIETVK 631
+T K + N + P GG ++ + KL++ +SK+GSL N ++ PGGG+KKIET K
Sbjct: 227 SKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHK 286
Query: 632 LDFGE 646
L F E
Sbjct: 287 LTFRE 291
Score = 61.3 bits (142), Expect = 3e-09
Identities = 39/92 (42%), Positives = 55/92 (59%), Gaps = 4/92 (4%)
Frame = +2
Query: 332 KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGN-ITPKIAA-KNEAYT 505
KVQ+ P +L V SK GSL N +KPGGG+V++++ KL+F + + KI + N +
Sbjct: 216 KVQIVYKPV-DLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHV 274
Query: 506 PSGGAKKIVTNKLEW--NAKSKVGSLQNASYK 595
P GG KKI T+KL + NAK+K YK
Sbjct: 275 PGGGNKKIETHKLTFRENAKAKTDHGAEIVYK 306
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/114 (27%), Positives = 59/114 (51%), Gaps = 5/114 (4%)
Frame = +2
Query: 323 PMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKL---EFGNITPKIAA-K 490
P ++ + + P+P + K K+ + P K +++ + + N+ KI + +
Sbjct: 148 PGSRSRTPSLPTPPTREPK-KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTE 206
Query: 491 NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKLDFGEK 649
N + P GG +IV ++ + SK GSL N +KPGGG ++++ KLDF ++
Sbjct: 207 NLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDR 260
>BC114504-1|AAI14505.1| 352|Homo sapiens microtubule-associated
protein tau, isoform 4 protein.
Length = 352
Score = 97.9 bits (233), Expect = 3e-20
Identities = 50/125 (40%), Positives = 76/125 (60%), Gaps = 3/125 (2%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K + TP + +++Q P P+LK VKSKIGS +N ++PGGGKV+I + ++
Sbjct: 167 KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIVYKPVDL 226
Query: 461 GNITPKIAA-KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIETVK 631
+T K + N + P GG ++ + KL++ +SK+GSL N ++ PGGG+KKIET K
Sbjct: 227 SKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHK 286
Query: 632 LDFGE 646
L F E
Sbjct: 287 LTFRE 291
Score = 61.3 bits (142), Expect = 3e-09
Identities = 39/92 (42%), Positives = 55/92 (59%), Gaps = 4/92 (4%)
Frame = +2
Query: 332 KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGN-ITPKIAA-KNEAYT 505
KVQ+ P +L V SK GSL N +KPGGG+V++++ KL+F + + KI + N +
Sbjct: 216 KVQIVYKPV-DLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHV 274
Query: 506 PSGGAKKIVTNKLEW--NAKSKVGSLQNASYK 595
P GG KKI T+KL + NAK+K YK
Sbjct: 275 PGGGNKKIETHKLTFRENAKAKTDHGAEIVYK 306
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/114 (27%), Positives = 59/114 (51%), Gaps = 5/114 (4%)
Frame = +2
Query: 323 PMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKL---EFGNITPKIAA-K 490
P ++ + + P+P + K K+ + P K +++ + + N+ KI + +
Sbjct: 148 PGSRSRTPSLPTPPTREPK-KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTE 206
Query: 491 NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKLDFGEK 649
N + P GG +IV ++ + SK GSL N +KPGGG ++++ KLDF ++
Sbjct: 207 NLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDR 260
>BC101936-1|AAI01937.1| 352|Homo sapiens microtubule-associated
protein tau protein.
Length = 352
Score = 97.9 bits (233), Expect = 3e-20
Identities = 50/125 (40%), Positives = 76/125 (60%), Gaps = 3/125 (2%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K + TP + +++Q P P+LK VKSKIGS +N ++PGGGKV+I + ++
Sbjct: 167 KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIVYKPVDL 226
Query: 461 GNITPKIAA-KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIETVK 631
+T K + N + P GG ++ + KL++ +SK+GSL N ++ PGGG+KKIET K
Sbjct: 227 SKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHK 286
Query: 632 LDFGE 646
L F E
Sbjct: 287 LTFRE 291
Score = 61.3 bits (142), Expect = 3e-09
Identities = 39/92 (42%), Positives = 55/92 (59%), Gaps = 4/92 (4%)
Frame = +2
Query: 332 KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGN-ITPKIAA-KNEAYT 505
KVQ+ P +L V SK GSL N +KPGGG+V++++ KL+F + + KI + N +
Sbjct: 216 KVQIVYKPV-DLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHV 274
Query: 506 PSGGAKKIVTNKLEW--NAKSKVGSLQNASYK 595
P GG KKI T+KL + NAK+K YK
Sbjct: 275 PGGGNKKIETHKLTFRENAKAKTDHGAEIVYK 306
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/114 (27%), Positives = 59/114 (51%), Gaps = 5/114 (4%)
Frame = +2
Query: 323 PMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKL---EFGNITPKIAA-K 490
P ++ + + P+P + K K+ + P K +++ + + N+ KI + +
Sbjct: 148 PGSRSRTPSLPTPPTREPK-KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTE 206
Query: 491 NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKLDFGEK 649
N + P GG +IV ++ + SK GSL N +KPGGG ++++ KLDF ++
Sbjct: 207 NLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDR 260
>BC099721-1|AAH99721.1| 352|Homo sapiens microtubule-associated
protein tau protein.
Length = 352
Score = 97.9 bits (233), Expect = 3e-20
Identities = 50/125 (40%), Positives = 76/125 (60%), Gaps = 3/125 (2%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K + TP + +++Q P P+LK VKSKIGS +N ++PGGGKV+I + ++
Sbjct: 167 KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIVYKPVDL 226
Query: 461 GNITPKIAA-KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIETVK 631
+T K + N + P GG ++ + KL++ +SK+GSL N ++ PGGG+KKIET K
Sbjct: 227 SKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHK 286
Query: 632 LDFGE 646
L F E
Sbjct: 287 LTFRE 291
Score = 61.3 bits (142), Expect = 3e-09
Identities = 39/92 (42%), Positives = 55/92 (59%), Gaps = 4/92 (4%)
Frame = +2
Query: 332 KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGN-ITPKIAA-KNEAYT 505
KVQ+ P +L V SK GSL N +KPGGG+V++++ KL+F + + KI + N +
Sbjct: 216 KVQIVYKPV-DLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHV 274
Query: 506 PSGGAKKIVTNKLEW--NAKSKVGSLQNASYK 595
P GG KKI T+KL + NAK+K YK
Sbjct: 275 PGGGNKKIETHKLTFRENAKAKTDHGAEIVYK 306
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/114 (27%), Positives = 59/114 (51%), Gaps = 5/114 (4%)
Frame = +2
Query: 323 PMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKL---EFGNITPKIAA-K 490
P ++ + + P+P + K K+ + P K +++ + + N+ KI + +
Sbjct: 148 PGSRSRTPSLPTPPTREPK-KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTE 206
Query: 491 NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKLDFGEK 649
N + P GG +IV ++ + SK GSL N +KPGGG ++++ KLDF ++
Sbjct: 207 NLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDR 260
>BC098281-1|AAH98281.1| 352|Homo sapiens microtubule-associated
protein tau protein.
Length = 352
Score = 97.9 bits (233), Expect = 3e-20
Identities = 50/125 (40%), Positives = 76/125 (60%), Gaps = 3/125 (2%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K + TP + +++Q P P+LK VKSKIGS +N ++PGGGKV+I + ++
Sbjct: 167 KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIVYKPVDL 226
Query: 461 GNITPKIAA-KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIETVK 631
+T K + N + P GG ++ + KL++ +SK+GSL N ++ PGGG+KKIET K
Sbjct: 227 SKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHK 286
Query: 632 LDFGE 646
L F E
Sbjct: 287 LTFRE 291
Score = 61.3 bits (142), Expect = 3e-09
Identities = 39/92 (42%), Positives = 55/92 (59%), Gaps = 4/92 (4%)
Frame = +2
Query: 332 KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGN-ITPKIAA-KNEAYT 505
KVQ+ P +L V SK GSL N +KPGGG+V++++ KL+F + + KI + N +
Sbjct: 216 KVQIVYKPV-DLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHV 274
Query: 506 PSGGAKKIVTNKLEW--NAKSKVGSLQNASYK 595
P GG KKI T+KL + NAK+K YK
Sbjct: 275 PGGGNKKIETHKLTFRENAKAKTDHGAEIVYK 306
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/114 (27%), Positives = 59/114 (51%), Gaps = 5/114 (4%)
Frame = +2
Query: 323 PMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKL---EFGNITPKIAA-K 490
P ++ + + P+P + K K+ + P K +++ + + N+ KI + +
Sbjct: 148 PGSRSRTPSLPTPPTREPK-KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTE 206
Query: 491 NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKLDFGEK 649
N + P GG +IV ++ + SK GSL N +KPGGG ++++ KLDF ++
Sbjct: 207 NLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDR 260
>BC000558-1|AAH00558.1| 352|Homo sapiens microtubule-associated
protein tau protein.
Length = 352
Score = 97.9 bits (233), Expect = 3e-20
Identities = 50/125 (40%), Positives = 76/125 (60%), Gaps = 3/125 (2%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K + TP + +++Q P P+LK VKSKIGS +N ++PGGGKV+I + ++
Sbjct: 167 KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIVYKPVDL 226
Query: 461 GNITPKIAA-KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIETVK 631
+T K + N + P GG ++ + KL++ +SK+GSL N ++ PGGG+KKIET K
Sbjct: 227 SKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHK 286
Query: 632 LDFGE 646
L F E
Sbjct: 287 LTFRE 291
Score = 61.3 bits (142), Expect = 3e-09
Identities = 39/92 (42%), Positives = 55/92 (59%), Gaps = 4/92 (4%)
Frame = +2
Query: 332 KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGN-ITPKIAA-KNEAYT 505
KVQ+ P +L V SK GSL N +KPGGG+V++++ KL+F + + KI + N +
Sbjct: 216 KVQIVYKPV-DLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHV 274
Query: 506 PSGGAKKIVTNKLEW--NAKSKVGSLQNASYK 595
P GG KKI T+KL + NAK+K YK
Sbjct: 275 PGGGNKKIETHKLTFRENAKAKTDHGAEIVYK 306
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/114 (27%), Positives = 59/114 (51%), Gaps = 5/114 (4%)
Frame = +2
Query: 323 PMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKL---EFGNITPKIAA-K 490
P ++ + + P+P + K K+ + P K +++ + + N+ KI + +
Sbjct: 148 PGSRSRTPSLPTPPTREPK-KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTE 206
Query: 491 NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKLDFGEK 649
N + P GG +IV ++ + SK GSL N +KPGGG ++++ KLDF ++
Sbjct: 207 NLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDR 260
>AF047863-3|AAC04278.1| 352|Homo sapiens CNS specific
microtubule-associated protein tau, fetal isoform
protein.
Length = 352
Score = 97.9 bits (233), Expect = 3e-20
Identities = 50/125 (40%), Positives = 76/125 (60%), Gaps = 3/125 (2%)
Frame = +2
Query: 281 KTPEIPTPTEKKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF 460
K + TP + +++Q P P+LK VKSKIGS +N ++PGGGKV+I + ++
Sbjct: 167 KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIVYKPVDL 226
Query: 461 GNITPKIAA-KNEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIETVK 631
+T K + N + P GG ++ + KL++ +SK+GSL N ++ PGGG+KKIET K
Sbjct: 227 SKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHK 286
Query: 632 LDFGE 646
L F E
Sbjct: 287 LTFRE 291
Score = 61.3 bits (142), Expect = 3e-09
Identities = 39/92 (42%), Positives = 55/92 (59%), Gaps = 4/92 (4%)
Frame = +2
Query: 332 KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGN-ITPKIAA-KNEAYT 505
KVQ+ P +L V SK GSL N +KPGGG+V++++ KL+F + + KI + N +
Sbjct: 216 KVQIVYKPV-DLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHV 274
Query: 506 PSGGAKKIVTNKLEW--NAKSKVGSLQNASYK 595
P GG KKI T+KL + NAK+K YK
Sbjct: 275 PGGGNKKIETHKLTFRENAKAKTDHGAEIVYK 306
Score = 49.6 bits (113), Expect = 1e-05
Identities = 31/114 (27%), Positives = 59/114 (51%), Gaps = 5/114 (4%)
Frame = +2
Query: 323 PMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKL---EFGNITPKIAA-K 490
P ++ + + P+P + K K+ + P K +++ + + N+ KI + +
Sbjct: 148 PGSRSRTPSLPTPPTREPK-KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTE 206
Query: 491 NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKLDFGEK 649
N + P GG +IV ++ + SK GSL N +KPGGG ++++ KLDF ++
Sbjct: 207 NLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDR 260
>S76756-1|AAB33379.1| 125|Homo sapiens microtubule-associated
protein 2 4R isoform protein.
Length = 125
Score = 94.3 bits (224), Expect = 3e-19
Identities = 48/98 (48%), Positives = 68/98 (69%), Gaps = 2/98 (2%)
Frame = +2
Query: 362 NLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK-NEAYTPSGGAKKIVTN 538
+LK VKSKIGS DN Y+P GG+V+I N+K++F + + +K N ++ GG +IVT
Sbjct: 1 DLKNVKSKIGSTDNIKYQPKGGQVRILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTK 60
Query: 539 KLEW-NAKSKVGSLQNASYKPGGGDKKIETVKLDFGEK 649
K++ + SK GSL+N ++PGGG KIE+VKLDF EK
Sbjct: 61 KIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEK 98
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/90 (43%), Positives = 59/90 (65%), Gaps = 3/90 (3%)
Frame = +2
Query: 374 VKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAA-KNEAYTPSGGAKKIVTNKLEW 550
V+S+ GS DN + GGG V+I +K++ ++T K + KN + P GG KI + KL++
Sbjct: 36 VQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDF 95
Query: 551 N--AKSKVGSLQNASYKPGGGDKKIETVKL 634
A++KVGSL NA + PGGG+ KI++ KL
Sbjct: 96 KEKAQAKVGSLDNAHHVPGGGNVKIDSQKL 125
>AB209377-1|BAD92614.1| 1163|Homo sapiens microtubule-associated
protein 4 isoform 1 variant protein.
Length = 1163
Score = 82.6 bits (195), Expect = 1e-15
Identities = 45/112 (40%), Positives = 67/112 (59%), Gaps = 3/112 (2%)
Frame = +2
Query: 314 KKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK- 490
+K P KVQ+ + + ++SK GS DN + PGGG V+I+N+K++ ++ K +K
Sbjct: 1013 QKQPAGKVQIVSK-KVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKA 1071
Query: 491 NEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIETVKLDF 640
N + P GG KI + KL + A++KVGSL N + P GG KIET +L F
Sbjct: 1072 NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKIETYRLTF 1123
Score = 67.7 bits (158), Expect = 3e-11
Identities = 41/115 (35%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Frame = +2
Query: 311 KKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK 490
+ KV P AV G + +A +P G KV+I ++K+ + +I K +K
Sbjct: 981 RAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAG-KVQIVSKKVSYSHIQSKCGSK 1039
Query: 491 -NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKLDFGEK 649
N + P GG +I K++ + SK GS N +KPGGGD KIE+ KL+F EK
Sbjct: 1040 DNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEK 1094
Score = 65.7 bits (153), Expect = 1e-10
Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 9/109 (8%)
Frame = +2
Query: 347 NAPSPNLKAVKSKIGSLDNATYKPGGGKVKIE--------NRKLEFGNITPKIAAKNEAY 502
N +P+LK V+SK+GS +N ++PGGG+ K+E RK E +T A
Sbjct: 954 NTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQ 1013
Query: 503 TPSGGAKKIVTNKLEW-NAKSKVGSLQNASYKPGGGDKKIETVKLDFGE 646
G +IV+ K+ + + +SK GS N + PGGG+ +I+ K+D +
Sbjct: 1014 KQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISK 1062
>U19727-1|AAA67361.1| 1152|Homo sapiens microtubule-associated protein
4 protein.
Length = 1152
Score = 74.5 bits (175), Expect = 3e-13
Identities = 41/106 (38%), Positives = 62/106 (58%), Gaps = 3/106 (2%)
Frame = +2
Query: 314 KKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK- 490
+K P KVQ+ + + ++SK GS DN + PGGG V+I+N+K++ ++ K +K
Sbjct: 985 QKQPAGKVQIVSK-KVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKA 1043
Query: 491 NEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIE 622
N + P GG KI + KL + A++KVGSL N + P GG K E
Sbjct: 1044 NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089
Score = 67.7 bits (158), Expect = 3e-11
Identities = 41/115 (35%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Frame = +2
Query: 311 KKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK 490
+ KV P AV G + +A +P G KV+I ++K+ + +I K +K
Sbjct: 953 RAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAG-KVQIVSKKVSYSHIQSKCGSK 1011
Query: 491 -NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKLDFGEK 649
N + P GG +I K++ + SK GS N +KPGGGD KIE+ KL+F EK
Sbjct: 1012 DNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEK 1066
Score = 65.7 bits (153), Expect = 1e-10
Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 9/109 (8%)
Frame = +2
Query: 347 NAPSPNLKAVKSKIGSLDNATYKPGGGKVKIE--------NRKLEFGNITPKIAAKNEAY 502
N +P+LK V+SK+GS +N ++PGGG+ K+E RK E +T A
Sbjct: 926 NTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQ 985
Query: 503 TPSGGAKKIVTNKLEW-NAKSKVGSLQNASYKPGGGDKKIETVKLDFGE 646
G +IV+ K+ + + +SK GS N + PGGG+ +I+ K+D +
Sbjct: 986 KQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISK 1034
>M64571-1|AAA59553.1| 1152|Homo sapiens microtubule-associated protein
4 protein.
Length = 1152
Score = 74.5 bits (175), Expect = 3e-13
Identities = 41/106 (38%), Positives = 62/106 (58%), Gaps = 3/106 (2%)
Frame = +2
Query: 314 KKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK- 490
+K P KVQ+ + + ++SK GS DN + PGGG V+I+N+K++ ++ K +K
Sbjct: 985 QKQPAGKVQIVSK-KVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKA 1043
Query: 491 NEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIE 622
N + P GG KI + KL + A++KVGSL N + P GG K E
Sbjct: 1044 NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089
Score = 67.7 bits (158), Expect = 3e-11
Identities = 41/115 (35%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Frame = +2
Query: 311 KKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK 490
+ KV P AV G + +A +P G KV+I ++K+ + +I K +K
Sbjct: 953 RAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAG-KVQIVSKKVSYSHIQSKCGSK 1011
Query: 491 -NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKLDFGEK 649
N + P GG +I K++ + SK GS N +KPGGGD KIE+ KL+F EK
Sbjct: 1012 DNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEK 1066
Score = 65.7 bits (153), Expect = 1e-10
Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 9/109 (8%)
Frame = +2
Query: 347 NAPSPNLKAVKSKIGSLDNATYKPGGGKVKIE--------NRKLEFGNITPKIAAKNEAY 502
N +P+LK V+SK+GS +N ++PGGG+ K+E RK E +T A
Sbjct: 926 NTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQ 985
Query: 503 TPSGGAKKIVTNKLEW-NAKSKVGSLQNASYKPGGGDKKIETVKLDFGE 646
G +IV+ K+ + + +SK GS N + PGGG+ +I+ K+D +
Sbjct: 986 KQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISK 1034
>BC048200-1|AAH48200.1| 857|Homo sapiens MAP4 protein protein.
Length = 857
Score = 74.5 bits (175), Expect = 3e-13
Identities = 41/106 (38%), Positives = 62/106 (58%), Gaps = 3/106 (2%)
Frame = +2
Query: 314 KKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK- 490
+K P KVQ+ + + ++SK GS DN + PGGG V+I+N+K++ ++ K +K
Sbjct: 690 QKQPAGKVQIVSK-KVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKA 748
Query: 491 NEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIE 622
N + P GG KI + KL + A++KVGSL N + P GG K E
Sbjct: 749 NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 794
Score = 67.7 bits (158), Expect = 3e-11
Identities = 41/115 (35%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Frame = +2
Query: 311 KKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK 490
+ KV P AV G + +A +P G KV+I ++K+ + +I K +K
Sbjct: 658 RAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAG-KVQIVSKKVSYSHIQSKCGSK 716
Query: 491 -NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKLDFGEK 649
N + P GG +I K++ + SK GS N +KPGGGD KIE+ KL+F EK
Sbjct: 717 DNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEK 771
Score = 65.7 bits (153), Expect = 1e-10
Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 9/109 (8%)
Frame = +2
Query: 347 NAPSPNLKAVKSKIGSLDNATYKPGGGKVKIE--------NRKLEFGNITPKIAAKNEAY 502
N +P+LK V+SK+GS +N ++PGGG+ K+E RK E +T A
Sbjct: 631 NTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQ 690
Query: 503 TPSGGAKKIVTNKLEW-NAKSKVGSLQNASYKPGGGDKKIETVKLDFGE 646
G +IV+ K+ + + +SK GS N + PGGG+ +I+ K+D +
Sbjct: 691 KQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISK 739
>BC015149-1|AAH15149.1| 979|Homo sapiens MAP4 protein protein.
Length = 979
Score = 74.5 bits (175), Expect = 3e-13
Identities = 41/106 (38%), Positives = 62/106 (58%), Gaps = 3/106 (2%)
Frame = +2
Query: 314 KKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK- 490
+K P KVQ+ + + ++SK GS DN + PGGG V+I+N+K++ ++ K +K
Sbjct: 812 QKQPAGKVQIVSK-KVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKA 870
Query: 491 NEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIE 622
N + P GG KI + KL + A++KVGSL N + P GG K E
Sbjct: 871 NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 916
Score = 67.7 bits (158), Expect = 3e-11
Identities = 41/115 (35%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Frame = +2
Query: 311 KKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK 490
+ KV P AV G + +A +P G KV+I ++K+ + +I K +K
Sbjct: 780 RAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAG-KVQIVSKKVSYSHIQSKCGSK 838
Query: 491 -NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKLDFGEK 649
N + P GG +I K++ + SK GS N +KPGGGD KIE+ KL+F EK
Sbjct: 839 DNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEK 893
Score = 65.7 bits (153), Expect = 1e-10
Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 9/109 (8%)
Frame = +2
Query: 347 NAPSPNLKAVKSKIGSLDNATYKPGGGKVKIE--------NRKLEFGNITPKIAAKNEAY 502
N +P+LK V+SK+GS +N ++PGGG+ K+E RK E +T A
Sbjct: 753 NTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQ 812
Query: 503 TPSGGAKKIVTNKLEW-NAKSKVGSLQNASYKPGGGDKKIETVKLDFGE 646
G +IV+ K+ + + +SK GS N + PGGG+ +I+ K+D +
Sbjct: 813 KQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISK 861
>BC012794-1|AAH12794.1| 979|Homo sapiens MAP4 protein protein.
Length = 979
Score = 74.5 bits (175), Expect = 3e-13
Identities = 41/106 (38%), Positives = 62/106 (58%), Gaps = 3/106 (2%)
Frame = +2
Query: 314 KKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK- 490
+K P KVQ+ + + ++SK GS DN + PGGG V+I+N+K++ ++ K +K
Sbjct: 812 QKQPAGKVQIVSK-KVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKA 870
Query: 491 NEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIE 622
N + P GG KI + KL + A++KVGSL N + P GG K E
Sbjct: 871 NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 916
Score = 67.7 bits (158), Expect = 3e-11
Identities = 41/115 (35%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Frame = +2
Query: 311 KKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK 490
+ KV P AV G + +A +P G KV+I ++K+ + +I K +K
Sbjct: 780 RAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAG-KVQIVSKKVSYSHIQSKCGSK 838
Query: 491 -NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKLDFGEK 649
N + P GG +I K++ + SK GS N +KPGGGD KIE+ KL+F EK
Sbjct: 839 DNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEK 893
Score = 65.7 bits (153), Expect = 1e-10
Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 9/109 (8%)
Frame = +2
Query: 347 NAPSPNLKAVKSKIGSLDNATYKPGGGKVKIE--------NRKLEFGNITPKIAAKNEAY 502
N +P+LK V+SK+GS +N ++PGGG+ K+E RK E +T A
Sbjct: 753 NTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQ 812
Query: 503 TPSGGAKKIVTNKLEW-NAKSKVGSLQNASYKPGGGDKKIETVKLDFGE 646
G +IV+ K+ + + +SK GS N + PGGG+ +I+ K+D +
Sbjct: 813 KQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISK 861
>BC008715-1|AAH08715.1| 979|Homo sapiens MAP4 protein protein.
Length = 979
Score = 74.5 bits (175), Expect = 3e-13
Identities = 41/106 (38%), Positives = 62/106 (58%), Gaps = 3/106 (2%)
Frame = +2
Query: 314 KKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK- 490
+K P KVQ+ + + ++SK GS DN + PGGG V+I+N+K++ ++ K +K
Sbjct: 812 QKQPAGKVQIVSK-KVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKA 870
Query: 491 NEAYTPSGGAKKIVTNKLEW--NAKSKVGSLQNASYKPGGGDKKIE 622
N + P GG KI + KL + A++KVGSL N + P GG K E
Sbjct: 871 NIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 916
Score = 67.7 bits (158), Expect = 3e-11
Identities = 41/115 (35%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Frame = +2
Query: 311 KKKVPMNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK 490
+ KV P AV G + +A +P G KV+I ++K+ + +I K +K
Sbjct: 780 RAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAG-KVQIVSKKVSYSHIQSKCGSK 838
Query: 491 -NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPGGGDKKIETVKLDFGEK 649
N + P GG +I K++ + SK GS N +KPGGGD KIE+ KL+F EK
Sbjct: 839 DNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEK 893
Score = 65.7 bits (153), Expect = 1e-10
Identities = 37/109 (33%), Positives = 59/109 (54%), Gaps = 9/109 (8%)
Frame = +2
Query: 347 NAPSPNLKAVKSKIGSLDNATYKPGGGKVKIE--------NRKLEFGNITPKIAAKNEAY 502
N +P+LK V+SK+GS +N ++PGGG+ K+E RK E +T A
Sbjct: 753 NTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQ 812
Query: 503 TPSGGAKKIVTNKLEW-NAKSKVGSLQNASYKPGGGDKKIETVKLDFGE 646
G +IV+ K+ + + +SK GS N + PGGG+ +I+ K+D +
Sbjct: 813 KQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISK 861
>AL831878-1|CAD38562.1| 187|Homo sapiens hypothetical protein
protein.
Length = 187
Score = 70.9 bits (166), Expect = 4e-12
Identities = 36/86 (41%), Positives = 53/86 (61%), Gaps = 3/86 (3%)
Frame = +2
Query: 374 VKSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAK-NEAYTPSGGAKKIVTNKLEW 550
++SK GS DN + PGGG V+I+N+K++ ++ K +K N + P GG KI + KL +
Sbjct: 39 IQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNF 98
Query: 551 --NAKSKVGSLQNASYKPGGGDKKIE 622
A++KVGSL N + P GG K E
Sbjct: 99 KEKAQAKVGSLDNVGHLPAGGAVKTE 124
Score = 58.8 bits (136), Expect = 2e-08
Identities = 32/76 (42%), Positives = 47/76 (61%), Gaps = 2/76 (2%)
Frame = +2
Query: 428 KVKIENRKLEFGNITPKIAAK-NEAYTPSGGAKKIVTNKLEWN-AKSKVGSLQNASYKPG 601
KV+I ++K+ + +I K +K N + P GG +I K++ + SK GS N +KPG
Sbjct: 26 KVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPG 85
Query: 602 GGDKKIETVKLDFGEK 649
GGD KIE+ KL+F EK
Sbjct: 86 GGDVKIESQKLNFKEK 101
Score = 46.8 bits (106), Expect = 7e-05
Identities = 31/74 (41%), Positives = 41/74 (55%), Gaps = 3/74 (4%)
Frame = +2
Query: 314 KKVPMN-KVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEF-GNITPKIAA 487
K VP VQ+ N ++ V SK GS N +KPGGG VKIE++KL F K+ +
Sbjct: 50 KHVPGGGNVQIQNK-KVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGS 108
Query: 488 -KNEAYTPSGGAKK 526
N + P+GGA K
Sbjct: 109 LDNVGHLPAGGAVK 122
>BC024302-1|AAH24302.1| 339|Homo sapiens Unknown (protein for
IMAGE:3349693) protein.
Length = 339
Score = 52.4 bits (120), Expect = 1e-06
Identities = 34/113 (30%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
Frame = +2
Query: 296 PTPTEKKKVP-MNKVQVGNAPSPNLKAVKSKIGSLDNATYKPGGGKVKIENRKLEFGNIT 472
P P+ P ++K PS + + K KV+I+N+K++ ++
Sbjct: 164 PMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVQIQNKKVDISKVS 223
Query: 473 PKIAAK-NEAYTPSGGAKKIVTNKLEWN--AKSKVGSLQNASYKPGGGDKKIE 622
K +K N + P GG KI + KL + A++KVGSL N + P GG K E
Sbjct: 224 SKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 276
Score = 41.5 bits (93), Expect = 0.003
Identities = 19/30 (63%), Positives = 22/30 (73%)
Frame = +2
Query: 560 SKVGSLQNASYKPGGGDKKIETVKLDFGEK 649
SK GS N +KPGGGD KIE+ KL+F EK
Sbjct: 224 SKCGSKANIKHKPGGGDVKIESQKLNFKEK 253
Score = 31.1 bits (67), Expect = 3.6
Identities = 27/87 (31%), Positives = 36/87 (41%)
Frame = +2
Query: 377 KSKIGSLDNATYKPGGGKVKIENRKLEFGNITPKIAAKNEAYTPSGGAKKIVTNKLEWNA 556
++K+GSLDN + P GG VK E G+ P P+G I E A
Sbjct: 255 QAKVGSLDNVGHLPAGGAVKTEGG----GSEAPLCPG-----PPAGEEPAISEAAPEAGA 305
Query: 557 KSKVGSLQNASYKPGGGDKKIETVKLD 637
+ L GGGD++ E LD
Sbjct: 306 PTSASGLNGHPTLSGGGDQR-EAQTLD 331
>AK022730-1|BAB14209.1| 293|Homo sapiens protein ( Homo sapiens
cDNA FLJ12668 fis, clone NT2RM4002287. ).
Length = 293
Score = 30.3 bits (65), Expect = 6.2
Identities = 21/99 (21%), Positives = 41/99 (41%), Gaps = 3/99 (3%)
Frame = +2
Query: 122 NDSGVDESTQGNDLNGSPSSPNKKIVNKTPTKEXXXXXXXXXXXXXXXXXXTAKTPEIPT 301
N V+ + + +N PS+P++K +K + ++P + T
Sbjct: 21 NLESVNSPIEKSSVNYEPSNPSEK-GSKKINLSSDQNKSVSESNNDDVMLISVESPNLTT 79
Query: 302 PTEKKKVPMNKVQVG---NAPSPNLKAVKSKIGSLDNAT 409
PT K+ G N+P+ + AV+ K+ S+ + T
Sbjct: 80 PTTSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLT 118
>AJ415330-1|CAC94399.1| 87|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 87
Score = 29.9 bits (64), Expect = 8.2
Identities = 14/41 (34%), Positives = 21/41 (51%)
Frame = -1
Query: 153 PCVDSSTPLSLSPSEI*YLIRLCRADTVITALSYTSRPGEH 31
P + S +SL S+ + +RLC TA+ Y +R G H
Sbjct: 29 PSLKSRVTMSLDASKSQFSLRLCSFTAADTAIYYCAREGRH 69
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 95,590,729
Number of Sequences: 237096
Number of extensions: 2089653
Number of successful extensions: 8079
Number of sequences better than 10.0: 33
Number of HSP's better than 10.0 without gapping: 7640
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7935
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7253890590
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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