Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fprWP12_F_B11
(628 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 59 1e-08
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 59 1e-08
AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 59 1e-08
AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 59 1e-08
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 56 8e-08
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 56 8e-08
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 53 7e-07
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 53 7e-07
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 53 7e-07
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 53 7e-07
BC096286-1|AAH96286.1| 437|Homo sapiens cytochrome P450, family... 53 7e-07
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 53 7e-07
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 50 9e-06
BC001776-1|AAH01776.1| 217|Homo sapiens CYP27B1 protein protein. 44 3e-04
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 44 3e-04
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 44 3e-04
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 44 3e-04
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 44 3e-04
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 44 3e-04
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 44 3e-04
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 44 3e-04
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 44 3e-04
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 44 3e-04
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 40 0.005
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 40 0.005
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 40 0.005
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 40 0.005
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 40 0.005
D16153-1|BAB71992.1| 132|Homo sapiens cytochrome P-450c11 protein. 39 0.013
X97065-1|CAA65775.1| 767|Homo sapiens Sec23 protein protein. 34 0.36
BC095404-1|AAH95404.1| 767|Homo sapiens Sec23 homolog B (S. cer... 32 1.4
BC005404-1|AAH05404.1| 767|Homo sapiens SEC23B protein protein. 32 1.4
BC005032-1|AAH05032.1| 767|Homo sapiens Sec23 homolog B (S. cer... 32 1.4
AL121900-3|CAH73149.1| 767|Homo sapiens Sec23 homolog B (S. cer... 32 1.4
AL121893-8|CAI12512.1| 767|Homo sapiens Sec23 homolog B (S. cer... 32 1.4
>BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 58.8 bits (136), Expect = 1e-08
Identities = 33/113 (29%), Positives = 53/113 (46%)
Frame = +2
Query: 179 MPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISDPTHMK 358
+P S P++G+ + GG K H + HK+ G IF +L G + V + P ++
Sbjct: 58 LPGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKL-GSFESVHLGSPCLLE 116
Query: 359 SLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHLLR 517
+L+ E YP + +PW Y GL ++GEDW R K L++
Sbjct: 117 ALY-RTESAYPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMK 168
>BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 58.8 bits (136), Expect = 1e-08
Identities = 33/113 (29%), Positives = 53/113 (46%)
Frame = +2
Query: 179 MPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISDPTHMK 358
+P S P++G+ + GG K H + HK+ G IF +L G + V + P ++
Sbjct: 58 LPGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKL-GSFESVHLGSPCLLE 116
Query: 359 SLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHLLR 517
+L+ E YP + +PW Y GL ++GEDW R K L++
Sbjct: 117 ALY-RTESAYPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMK 168
>AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 448
Score = 58.8 bits (136), Expect = 1e-08
Identities = 33/113 (29%), Positives = 53/113 (46%)
Frame = +2
Query: 179 MPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISDPTHMK 358
+P S P++G+ + GG K H + HK+ G IF +L G + V + P ++
Sbjct: 58 LPGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKL-GSFESVHLGSPCLLE 116
Query: 359 SLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHLLR 517
+L+ E YP + +PW Y GL ++GEDW R K L++
Sbjct: 117 ALY-RTESAYPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMK 168
>AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 58.8 bits (136), Expect = 1e-08
Identities = 33/113 (29%), Positives = 53/113 (46%)
Frame = +2
Query: 179 MPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISDPTHMK 358
+P S P++G+ + GG K H + HK+ G IF +L G + V + P ++
Sbjct: 58 LPGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKL-GSFESVHLGSPCLLE 116
Query: 359 SLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHLLR 517
+L+ E YP + +PW Y GL ++GEDW R K L++
Sbjct: 117 ALY-RTESAYPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMK 168
>X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase
(P-450aldo) protein.
Length = 503
Score = 56.4 bits (130), Expect = 8e-08
Identities = 29/92 (31%), Positives = 51/92 (55%)
Frame = +2
Query: 239 GGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISDPTHMKSLFLNLEGKYPAHILPEPWV 418
G ++LH + ++LGPIF L G ++V + P ++ L ++ +P ++ EPWV
Sbjct: 60 GYEHLHLEMHQTFQELGPIFRYNLGGP-RMVCVMLPEDVEKL-QQVDSLHPCRMILEPWV 117
Query: 419 LYEKLYGSKRGLFFMDGEDWLINRRIMNKHLL 514
Y + G K G+F ++G +W NR +N +L
Sbjct: 118 AYRQHRGHKCGVFLLNGPEWRFNRLRLNPDVL 149
>D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase
protein.
Length = 503
Score = 56.4 bits (130), Expect = 8e-08
Identities = 29/92 (31%), Positives = 51/92 (55%)
Frame = +2
Query: 239 GGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISDPTHMKSLFLNLEGKYPAHILPEPWV 418
G ++LH + ++LGPIF L G ++V + P ++ L ++ +P ++ EPWV
Sbjct: 60 GYEHLHLEMHQTFQELGPIFRYNLGGP-RMVCVMLPEDVEKL-QQVDSLHPCRMILEPWV 117
Query: 419 LYEKLYGSKRGLFFMDGEDWLINRRIMNKHLL 514
Y + G K G+F ++G +W NR +N +L
Sbjct: 118 AYRQHRGHKCGVFLLNGPEWRFNRLRLNPDVL 149
>X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (11 Beta). ).
Length = 503
Score = 53.2 bits (122), Expect = 7e-07
Identities = 29/92 (31%), Positives = 49/92 (53%)
Frame = +2
Query: 239 GGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISDPTHMKSLFLNLEGKYPAHILPEPWV 418
G ++LH + ++LGPIF L G +V + P ++ L ++ +P + EPWV
Sbjct: 60 GYEDLHLEVHQTFQELGPIFRYDLGG-AGMVCVMLPEDVEKL-QQVDSLHPHRMSLEPWV 117
Query: 419 LYEKLYGSKRGLFFMDGEDWLINRRIMNKHLL 514
Y + G K G+F ++G +W NR +N +L
Sbjct: 118 AYRQHRGHKCGVFLLNGPEWRFNRLRLNPEVL 149
>M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid
11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exon 9.
).
Length = 503
Score = 53.2 bits (122), Expect = 7e-07
Identities = 28/92 (30%), Positives = 50/92 (54%)
Frame = +2
Query: 239 GGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISDPTHMKSLFLNLEGKYPAHILPEPWV 418
G ++LH + ++LGPIF L G ++V + P ++ L ++ +P ++ EPWV
Sbjct: 60 GYEHLHLEMHQTFQELGPIFRYNLGGP-RMVCVMLPEDVEKL-QQVDSLHPCRMILEPWV 117
Query: 419 LYEKLYGSKRGLFFMDGEDWLINRRIMNKHLL 514
+ G K G+F ++G +W NR +N +L
Sbjct: 118 AIRQHRGHKCGVFLLNGPEWRFNRLRLNPDVL 149
>M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein.
Length = 503
Score = 53.2 bits (122), Expect = 7e-07
Identities = 29/92 (31%), Positives = 49/92 (53%)
Frame = +2
Query: 239 GGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISDPTHMKSLFLNLEGKYPAHILPEPWV 418
G ++LH + ++LGPIF L G +V + P ++ L ++ +P + EPWV
Sbjct: 60 GYEDLHLEVHQTFQELGPIFRYDLGG-AGMVCVMLPEDVEKL-QQVDSLHPHRMSLEPWV 117
Query: 419 LYEKLYGSKRGLFFMDGEDWLINRRIMNKHLL 514
Y + G K G+F ++G +W NR +N +L
Sbjct: 118 AYRQHRGHKCGVFLLNGPEWRFNRLRLNPEVL 149
>BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family
11, subfamily B, polypeptide 1 protein.
Length = 503
Score = 53.2 bits (122), Expect = 7e-07
Identities = 29/92 (31%), Positives = 49/92 (53%)
Frame = +2
Query: 239 GGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISDPTHMKSLFLNLEGKYPAHILPEPWV 418
G ++LH + ++LGPIF L G +V + P ++ L ++ +P + EPWV
Sbjct: 60 GYEDLHLEVHQTFQELGPIFRYDLGG-AGMVCVMLPEDVEKL-QQVDSLHPHRMSLEPWV 117
Query: 419 LYEKLYGSKRGLFFMDGEDWLINRRIMNKHLL 514
Y + G K G+F ++G +W NR +N +L
Sbjct: 118 AYRQHRGHKCGVFLLNGPEWRFNRLRLNPEVL 149
>BC096286-1|AAH96286.1| 437|Homo sapiens cytochrome P450, family
11, subfamily B, polypeptide 1 protein.
Length = 437
Score = 53.2 bits (122), Expect = 7e-07
Identities = 29/92 (31%), Positives = 49/92 (53%)
Frame = +2
Query: 239 GGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISDPTHMKSLFLNLEGKYPAHILPEPWV 418
G ++LH + ++LGPIF L G +V + P ++ L ++ +P + EPWV
Sbjct: 60 GYEDLHLEVHQTFQELGPIFRYDLGG-AGMVCVMLPEDVEKL-QQVDSLHPHRMSLEPWV 117
Query: 419 LYEKLYGSKRGLFFMDGEDWLINRRIMNKHLL 514
Y + G K G+F ++G +W NR +N +L
Sbjct: 118 AYRQHRGHKCGVFLLNGPEWRFNRLRLNPEVL 149
>AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome
P-450c11 protein protein.
Length = 503
Score = 53.2 bits (122), Expect = 7e-07
Identities = 29/92 (31%), Positives = 49/92 (53%)
Frame = +2
Query: 239 GGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISDPTHMKSLFLNLEGKYPAHILPEPWV 418
G ++LH + ++LGPIF L G +V + P ++ L ++ +P + EPWV
Sbjct: 60 GYEDLHLEVHQTFQELGPIFRYDLGG-AGMVCVMLPEDVEKL-QQVDSLHPHRMSLEPWV 117
Query: 419 LYEKLYGSKRGLFFMDGEDWLINRRIMNKHLL 514
Y + G K G+F ++G +W NR +N +L
Sbjct: 118 AYRQHRGHKCGVFLLNGPEWRFNRLRLNPEVL 149
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 49.6 bits (113), Expect = 9e-06
Identities = 30/113 (26%), Positives = 50/113 (44%)
Frame = +2
Query: 179 MPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISDPTHMK 358
+P S P++ + + GG K H + HK+ G IF +L G + V + P ++
Sbjct: 58 LPGPTSWPLLASLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKL-GSFESVHLGSPCLLE 116
Query: 359 SLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHLLR 517
+L+ P + +PW Y GL ++GEDW R K L++
Sbjct: 117 ALYRT--ESVPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMK 167
>BC001776-1|AAH01776.1| 217|Homo sapiens CYP27B1 protein protein.
Length = 217
Score = 44.4 bits (100), Expect = 3e-04
Identities = 35/151 (23%), Positives = 62/151 (41%)
Frame = +2
Query: 152 HKSLRTIDEMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLV 331
H + R++ ++P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 332 FISDPTHMKSLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHL 511
+++ P ++ L L EG P PW + + GL +GE+W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 512 LREDSDVWLRAPIRTAVFHFICNWKLRAQSG 604
LR + + V + +LR Q G
Sbjct: 146 LRPQAAARYAGTLNNVVCDLV--RRLRRQRG 174
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 44.4 bits (100), Expect = 3e-04
Identities = 35/151 (23%), Positives = 62/151 (41%)
Frame = +2
Query: 152 HKSLRTIDEMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLV 331
H + R++ ++P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 332 FISDPTHMKSLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHL 511
+++ P ++ L L EG P PW + + GL +GE+W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 512 LREDSDVWLRAPIRTAVFHFICNWKLRAQSG 604
LR + + V + +LR Q G
Sbjct: 146 LRPQAAARYAGTLNNVVCDLV--RRLRRQRG 174
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 44.4 bits (100), Expect = 3e-04
Identities = 35/151 (23%), Positives = 62/151 (41%)
Frame = +2
Query: 152 HKSLRTIDEMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLV 331
H + R++ ++P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 332 FISDPTHMKSLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHL 511
+++ P ++ L L EG P PW + + GL +GE+W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 512 LREDSDVWLRAPIRTAVFHFICNWKLRAQSG 604
LR + + V + +LR Q G
Sbjct: 146 LRPQAAARYAGTLNNVVCDLV--RRLRRQRG 174
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 44.4 bits (100), Expect = 3e-04
Identities = 35/151 (23%), Positives = 62/151 (41%)
Frame = +2
Query: 152 HKSLRTIDEMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLV 331
H + R++ ++P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 332 FISDPTHMKSLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHL 511
+++ P ++ L L EG P PW + + GL +GE+W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 512 LREDSDVWLRAPIRTAVFHFICNWKLRAQSG 604
LR + + V + +LR Q G
Sbjct: 146 LRPQAAARYAGTLNNVVCDLV--RRLRRQRG 174
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 44.4 bits (100), Expect = 3e-04
Identities = 35/151 (23%), Positives = 62/151 (41%)
Frame = +2
Query: 152 HKSLRTIDEMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLV 331
H + R++ ++P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 332 FISDPTHMKSLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHL 511
+++ P ++ L L EG P PW + + GL +GE+W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 512 LREDSDVWLRAPIRTAVFHFICNWKLRAQSG 604
LR + + V + +LR Q G
Sbjct: 146 LRPQAAARYAGTLNNVVCDLV--RRLRRQRG 174
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 44.4 bits (100), Expect = 3e-04
Identities = 35/151 (23%), Positives = 62/151 (41%)
Frame = +2
Query: 152 HKSLRTIDEMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLV 331
H + R++ ++P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 332 FISDPTHMKSLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHL 511
+++ P ++ L L EG P PW + + GL +GE+W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 512 LREDSDVWLRAPIRTAVFHFICNWKLRAQSG 604
LR + + V + +LR Q G
Sbjct: 146 LRPQAAARYAGTLNNVVCDLV--RRLRRQRG 174
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 44.4 bits (100), Expect = 3e-04
Identities = 35/151 (23%), Positives = 62/151 (41%)
Frame = +2
Query: 152 HKSLRTIDEMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLV 331
H + R++ ++P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 332 FISDPTHMKSLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHL 511
+++ P ++ L L EG P PW + + GL +GE+W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 512 LREDSDVWLRAPIRTAVFHFICNWKLRAQSG 604
LR + + V + +LR Q G
Sbjct: 146 LRPQAAARYAGTLNNVVCDLV--RRLRRQRG 174
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 44.4 bits (100), Expect = 3e-04
Identities = 35/151 (23%), Positives = 62/151 (41%)
Frame = +2
Query: 152 HKSLRTIDEMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLV 331
H + R++ ++P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 332 FISDPTHMKSLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHL 511
+++ P ++ L L EG P PW + + GL +GE+W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 512 LREDSDVWLRAPIRTAVFHFICNWKLRAQSG 604
LR + + V + +LR Q G
Sbjct: 146 LRPQAAARYAGTLNNVVCDLV--RRLRRQRG 174
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 44.4 bits (100), Expect = 3e-04
Identities = 35/151 (23%), Positives = 62/151 (41%)
Frame = +2
Query: 152 HKSLRTIDEMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLV 331
H + R++ ++P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 332 FISDPTHMKSLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHL 511
+++ P ++ L L EG P PW + + GL +GE+W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 512 LREDSDVWLRAPIRTAVFHFICNWKLRAQSG 604
LR + + V + +LR Q G
Sbjct: 146 LRPQAAARYAGTLNNVVCDLV--RRLRRQRG 174
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 44.4 bits (100), Expect = 3e-04
Identities = 35/151 (23%), Positives = 62/151 (41%)
Frame = +2
Query: 152 HKSLRTIDEMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLV 331
H + R++ ++P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 332 FISDPTHMKSLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHL 511
+++ P ++ L L EG P PW + + GL +GE+W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 512 LREDSDVWLRAPIRTAVFHFICNWKLRAQSG 604
LR + + V + +LR Q G
Sbjct: 146 LRPQAAARYAGTLNNVVCDLV--RRLRRQRG 174
>X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase
protein.
Length = 530
Score = 40.3 bits (90), Expect = 0.005
Identities = 30/118 (25%), Positives = 50/118 (42%)
Frame = +2
Query: 164 RTIDEMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISD 343
R+++E+P L F LF G LH+ + + GP++ L + + S
Sbjct: 54 RSLEEIPRLGQLRFF---FQLFVQGYALQLHQLQVLYKAKYGPMWMSYLGPQMHVNLASA 110
Query: 344 PTHMKSLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHLLR 517
P + + EGKYP E W + + G F +G W R+ +N+ LL+
Sbjct: 111 P--LLEQVMRQEGKYPVRNDMELWKEHRDQHDLTYGPFTTEGHHWYQLRQALNQRLLK 166
>M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase
protein.
Length = 531
Score = 40.3 bits (90), Expect = 0.005
Identities = 30/118 (25%), Positives = 50/118 (42%)
Frame = +2
Query: 164 RTIDEMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISD 343
R+++E+P L F LF G LH+ + + GP++ L + + S
Sbjct: 55 RSLEEIPRLGQLRFF---FQLFVQGYALQLHQLQVLYKAKYGPMWMSYLGPQMHVNLASA 111
Query: 344 PTHMKSLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHLLR 517
P + + EGKYP E W + + G F +G W R+ +N+ LL+
Sbjct: 112 P--LLEQVMRQEGKYPVRNDMELWKEHRDQHDLTYGPFTTEGHHWYQLRQALNQRLLK 167
>BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 40.3 bits (90), Expect = 0.005
Identities = 30/118 (25%), Positives = 50/118 (42%)
Frame = +2
Query: 164 RTIDEMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISD 343
R+++E+P L F LF G LH+ + + GP++ L + + S
Sbjct: 55 RSLEEIPRLGQLRFF---FQLFVQGYALQLHQLQVLYKAKYGPMWMSYLGPQMHVNLASA 111
Query: 344 PTHMKSLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHLLR 517
P + + EGKYP E W + + G F +G W R+ +N+ LL+
Sbjct: 112 P--LLEQVMRQEGKYPVRNDMELWKEHRDQHDLTYGPFTTEGHHWYQLRQALNQRLLK 167
>BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 40.3 bits (90), Expect = 0.005
Identities = 30/118 (25%), Positives = 50/118 (42%)
Frame = +2
Query: 164 RTIDEMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISD 343
R+++E+P L F LF G LH+ + + GP++ L + + S
Sbjct: 55 RSLEEIPRLGQLRFF---FQLFVQGYALQLHQLQVLYKAKYGPMWMSYLGPQMHVNLASA 111
Query: 344 PTHMKSLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHLLR 517
P + + EGKYP E W + + G F +G W R+ +N+ LL+
Sbjct: 112 P--LLEQVMRQEGKYPVRNDMELWKEHRDQHDLTYGPFTTEGHHWYQLRQALNQRLLK 167
>AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase
protein.
Length = 531
Score = 40.3 bits (90), Expect = 0.005
Identities = 30/118 (25%), Positives = 50/118 (42%)
Frame = +2
Query: 164 RTIDEMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISD 343
R+++E+P L F LF G LH+ + + GP++ L + + S
Sbjct: 55 RSLEEIPRLGQLRFF---FQLFVQGYALQLHQLQVLYKAKYGPMWMSYLGPQMHVNLASA 111
Query: 344 PTHMKSLFLNLEGKYPAHILPEPWVLYEKLYGSKRGLFFMDGEDWLINRRIMNKHLLR 517
P + + EGKYP E W + + G F +G W R+ +N+ LL+
Sbjct: 112 P--LLEQVMRQEGKYPVRNDMELWKEHRDQHDLTYGPFTTEGHHWYQLRQALNQRLLK 167
>D16153-1|BAB71992.1| 132|Homo sapiens cytochrome P-450c11 protein.
Length = 132
Score = 39.1 bits (87), Expect = 0.013
Identities = 23/75 (30%), Positives = 39/75 (52%)
Frame = +2
Query: 239 GGKNLHKYIDMRHKQLGPIFYERLTGKTKLVFISDPTHMKSLFLNLEGKYPAHILPEPWV 418
G ++LH + ++LGPIF L G +V + P ++ L ++ +P + EPWV
Sbjct: 60 GYEDLHLEVHQTFQELGPIFRYDLGG-AGMVCVMLPEDVEKL-QQVDSLHPHRMSLEPWV 117
Query: 419 LYEKLYGSKRGLFFM 463
Y + G K G+F +
Sbjct: 118 AYRQHRGHKCGVFLL 132
>X97065-1|CAA65775.1| 767|Homo sapiens Sec23 protein protein.
Length = 767
Score = 34.3 bits (75), Expect = 0.36
Identities = 21/58 (36%), Positives = 31/58 (53%)
Frame = +1
Query: 382 KISGTYFTRTVGTV*KIIRIKKRTFLYGRRGLVD*STNYEQTSTQRRFRCMVTSSYKN 555
KI G T T+G +++ G RG + T+Y+Q+STQRR R VT+ +N
Sbjct: 449 KICGLDPTSTLGIYFEVVNQHNTPIPQGGRGAIQFVTHYQQSSTQRRIR--VTTIARN 504
>BC095404-1|AAH95404.1| 767|Homo sapiens Sec23 homolog B (S.
cerevisiae) protein.
Length = 767
Score = 32.3 bits (70), Expect = 1.4
Identities = 20/58 (34%), Positives = 30/58 (51%)
Frame = +1
Query: 382 KISGTYFTRTVGTV*KIIRIKKRTFLYGRRGLVD*STNYEQTSTQRRFRCMVTSSYKN 555
KI G T T+G +++ G RG + T+Y+ +STQRR R VT+ +N
Sbjct: 449 KICGLDPTSTLGIYFEVVNQHNTPIPQGGRGAIQFVTHYQHSSTQRRIR--VTTIARN 504
>BC005404-1|AAH05404.1| 767|Homo sapiens SEC23B protein protein.
Length = 767
Score = 32.3 bits (70), Expect = 1.4
Identities = 20/58 (34%), Positives = 30/58 (51%)
Frame = +1
Query: 382 KISGTYFTRTVGTV*KIIRIKKRTFLYGRRGLVD*STNYEQTSTQRRFRCMVTSSYKN 555
KI G T T+G +++ G RG + T+Y+ +STQRR R VT+ +N
Sbjct: 449 KICGLDPTSTLGIYFEVVNQHNTPIPQGGRGAIQFVTHYQHSSTQRRIR--VTTIARN 504
>BC005032-1|AAH05032.1| 767|Homo sapiens Sec23 homolog B (S.
cerevisiae) protein.
Length = 767
Score = 32.3 bits (70), Expect = 1.4
Identities = 20/58 (34%), Positives = 30/58 (51%)
Frame = +1
Query: 382 KISGTYFTRTVGTV*KIIRIKKRTFLYGRRGLVD*STNYEQTSTQRRFRCMVTSSYKN 555
KI G T T+G +++ G RG + T+Y+ +STQRR R VT+ +N
Sbjct: 449 KICGLDPTSTLGIYFEVVNQHNTPIPQGGRGAIQFVTHYQHSSTQRRIR--VTTIARN 504
>AL121900-3|CAH73149.1| 767|Homo sapiens Sec23 homolog B (S.
cerevisiae) protein.
Length = 767
Score = 32.3 bits (70), Expect = 1.4
Identities = 20/58 (34%), Positives = 30/58 (51%)
Frame = +1
Query: 382 KISGTYFTRTVGTV*KIIRIKKRTFLYGRRGLVD*STNYEQTSTQRRFRCMVTSSYKN 555
KI G T T+G +++ G RG + T+Y+ +STQRR R VT+ +N
Sbjct: 449 KICGLDPTSTLGIYFEVVNQHNTPIPQGGRGAIQFVTHYQHSSTQRRIR--VTTIARN 504
>AL121893-8|CAI12512.1| 767|Homo sapiens Sec23 homolog B (S.
cerevisiae) protein.
Length = 767
Score = 32.3 bits (70), Expect = 1.4
Identities = 20/58 (34%), Positives = 30/58 (51%)
Frame = +1
Query: 382 KISGTYFTRTVGTV*KIIRIKKRTFLYGRRGLVD*STNYEQTSTQRRFRCMVTSSYKN 555
KI G T T+G +++ G RG + T+Y+ +STQRR R VT+ +N
Sbjct: 449 KICGLDPTSTLGIYFEVVNQHNTPIPQGGRGAIQFVTHYQHSSTQRRIR--VTTIARN 504
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 91,755,718
Number of Sequences: 237096
Number of extensions: 1938914
Number of successful extensions: 4539
Number of sequences better than 10.0: 35
Number of HSP's better than 10.0 without gapping: 4462
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4530
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6804036910
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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