Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fprWP08_F_E18
(653 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein ... 231 1e-60
BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent kinase... 231 1e-60
AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent kinase... 231 1e-60
AY847283-1|AAW31760.1| 379|Homo sapiens cyclin-dependent kinase... 227 2e-59
AY845084-1|AAW30008.1| 315|Homo sapiens cyclin-dependent kinase... 227 2e-59
U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinas... 181 2e-45
BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent kinase... 181 2e-45
BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent kinase... 181 2e-45
BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein. 177 2e-44
AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protei... 177 2e-44
Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-l... 149 1e-35
Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein. 149 1e-35
AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase... 149 1e-35
AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent kinase... 149 1e-35
X66357-1|CAA47001.1| 305|Homo sapiens serine/threonine protein ... 138 2e-32
AY789470-1|AAV40830.1| 305|Homo sapiens cyclin-dependent kinase... 138 2e-32
X61622-1|CAA43807.1| 298|Homo sapiens CDK2 protein. 136 9e-32
X62071-1|CAA43985.1| 298|Homo sapiens cdk2 protein. 134 2e-31
M68520-1|AAA35667.1| 298|Homo sapiens cdc2-related protein kina... 134 2e-31
BT006821-1|AAP35467.1| 298|Homo sapiens cyclin-dependent kinase... 134 2e-31
BC035807-1|AAH35807.1| 292|Homo sapiens ICK protein protein. 134 2e-31
BC003065-1|AAH03065.1| 298|Homo sapiens cyclin-dependent kinase... 134 2e-31
AL162581-2|CAI19518.1| 632|Homo sapiens RP1-132F22.1 protein. 134 2e-31
AL031178-1|CAI20261.1| 632|Homo sapiens RP1-132F22.1 protein. 134 2e-31
AF512553-1|AAM34794.1| 298|Homo sapiens cyclin-dependent kinase... 134 2e-31
AF152469-1|AAG43364.1| 632|Homo sapiens MAK-related kinase prot... 134 2e-31
AB023153-1|BAA76780.2| 640|Homo sapiens KIAA0936 protein protein. 134 2e-31
AF390028-1|AAL58838.1| 993|Homo sapiens serine/threonine protei... 133 5e-31
AF225919-1|AAF37278.1| 632|Homo sapiens intestinal cell kinase ... 130 4e-30
BC039825-1|AAH39825.1| 457|Homo sapiens MAK protein protein. 129 7e-30
AL024498-4|CAB75823.1| 623|Homo sapiens protein ( ovel serine/t... 129 7e-30
AF505623-1|AAN16405.1| 623|Homo sapiens male germ cell-associat... 129 7e-30
X66365-1|CAA47008.1| 326|Homo sapiens serine/threonine protein ... 126 7e-29
BC052264-1|AAH52264.1| 326|Homo sapiens cyclin-dependent kinase... 126 7e-29
AY128534-1|AAM76970.1| 326|Homo sapiens cyclin-dependent kinase... 126 7e-29
Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycl... 124 2e-28
X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene... 124 2e-28
BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, ... 124 2e-28
BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein. 124 2e-28
BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, ... 124 2e-28
AF512554-1|AAM34793.1| 297|Homo sapiens cell division cycle 2, ... 124 2e-28
X66363-1|CAA47006.1| 496|Homo sapiens serine/threonine protein ... 121 2e-27
BT006827-1|AAP35473.1| 496|Homo sapiens PCTAIRE protein kinase ... 121 2e-27
BC015607-1|AAH15607.1| 496|Homo sapiens PCTAIRE protein kinase ... 121 2e-27
BC009852-1|AAH09852.2| 395|Homo sapiens PCTK1 protein protein. 121 2e-27
BC006190-1|AAH06190.1| 448|Homo sapiens PCTK1 protein protein. 121 2e-27
BC001048-1|AAH01048.1| 496|Homo sapiens PCTAIRE protein kinase ... 121 2e-27
AL096791-1|CAD20055.1| 496|Homo sapiens PCTAIRE protein kinase ... 121 2e-27
X66364-1|CAA47007.1| 292|Homo sapiens serine/threonine protein ... 121 3e-27
BT006680-1|AAP35326.1| 292|Homo sapiens cyclin-dependent kinase... 121 3e-27
BC005298-1|AAH05298.1| 346|Homo sapiens cyclin-dependent kinase... 121 3e-27
BC005115-1|AAH05115.1| 292|Homo sapiens cyclin-dependent kinase... 121 3e-27
AY049778-1|AAL15435.1| 292|Homo sapiens cyclin-dependent kinase... 121 3e-27
BT007299-1|AAP35963.1| 472|Homo sapiens PCTAIRE-motif protein k... 120 5e-27
BC011526-1|AAH11526.1| 472|Homo sapiens PCTAIRE protein kinase ... 120 5e-27
BC000281-1|AAH00281.2| 283|Homo sapiens PCTK3 protein protein. 120 5e-27
AY353238-1|AAR13066.1| 504|Homo sapiens PCTAIRE protein kinase ... 120 5e-27
AY353237-1|AAR13065.1| 474|Homo sapiens PCTAIRE protein kinase ... 120 5e-27
AL357131-4|CAH72012.1| 472|Homo sapiens PCTAIRE protein kinase ... 120 5e-27
AB209307-1|BAD92544.1| 436|Homo sapiens PCTAIRE protein kinase ... 120 5e-27
Z48970-1|CAA88834.1| 303|Homo sapiens orf protein. 119 8e-27
Y13120-1|CAA73587.1| 346|Homo sapiens serine/threonine protein ... 119 8e-27
X79193-1|CAA55785.1| 346|Homo sapiens MO15/CDK-activating kinas... 119 8e-27
X77743-1|CAA54793.1| 346|Homo sapiens CDK activating kinase pro... 119 8e-27
X77303-1|CAA54508.1| 346|Homo sapiens Cdk-activating kinase pro... 119 8e-27
U81031-1|AAC39521.2| 303|Homo sapiens CDK4 protein. 119 8e-27
U79269-1|AAB50213.1| 229|Homo sapiens cyclin dependent protein ... 119 8e-27
U37022-1|AAC50506.1| 303|Homo sapiens cyclin-dependent kinase 4... 119 8e-27
M14505-1|AAA35673.1| 303|Homo sapiens cyclin-dependent protein ... 119 8e-27
L20320-1|AAA36657.1| 346|Homo sapiens protein serine/threonine ... 119 8e-27
CR542247-1|CAG47043.1| 303|Homo sapiens CDK4 protein. 119 8e-27
CR407668-1|CAG28596.1| 303|Homo sapiens CDK4 protein. 119 8e-27
BC033005-1|AAH33005.1| 523|Homo sapiens PCTAIRE protein kinase ... 119 8e-27
BC010153-1|AAH10153.1| 303|Homo sapiens cyclin-dependent kinase... 119 8e-27
BC005864-1|AAH05864.1| 303|Homo sapiens cyclin-dependent kinase... 119 8e-27
BC003644-1|AAH03644.1| 303|Homo sapiens cyclin-dependent kinase... 119 8e-27
BC000834-1|AAH00834.1| 346|Homo sapiens cyclin-dependent kinase... 119 8e-27
AY130859-1|AAM77799.1| 346|Homo sapiens cyclin-dependent kinase... 119 8e-27
AF507942-1|AAM23014.1| 303|Homo sapiens cyclin-dependent kinase... 119 8e-27
CR457041-1|CAG33322.1| 292|Homo sapiens CDK5 protein. 119 1e-26
AF119833-1|AAG43234.1| 469|Homo sapiens serine/threonine protei... 119 1e-26
AC006036-1|AAF19245.1| 165|Homo sapiens unknown protein. 119 1e-26
AB020641-1|BAA74857.2| 453|Homo sapiens KIAA0834 protein protein. 119 1e-26
BC150265-1|AAI50266.1| 1481|Homo sapiens CRKRS protein protein. 118 1e-26
BC001274-1|AAH01274.1| 324|Homo sapiens CDC2L5 protein protein. 118 1e-26
AY679523-1|AAT74623.1| 1512|Homo sapiens cell division cycle 2-l... 118 1e-26
AJ297710-1|CAC10401.1| 1452|Homo sapiens CDC2L5 protein kinase p... 118 1e-26
AJ297709-1|CAC10400.1| 1512|Homo sapiens CDC2L5 protein kinase p... 118 1e-26
AF227198-1|AAF36401.1| 1490|Homo sapiens CrkRS protein. 118 1e-26
AB020711-1|BAA74927.2| 1535|Homo sapiens KIAA0904 protein protein. 118 1e-26
M80629-1|AAA58424.1| 418|Homo sapiens cdc2-related protein kina... 118 2e-26
AC006023-1|AAD54514.1| 727|Homo sapiens WUGSC:H_DJ1147A01.1 pro... 118 2e-26
X66360-1|CAA47004.1| 523|Homo sapiens serine/threonine protein ... 117 4e-26
X66362-1|CAA47005.1| 380|Homo sapiens serine/threonine protein ... 116 6e-26
X78342-1|CAA55137.1| 360|Homo sapiens PISSLRE protein. 112 9e-25
L33264-1|AAA60092.2| 314|Homo sapiens CDC2-related protein kina... 112 9e-25
BC025301-1|AAH25301.1| 272|Homo sapiens CDK10 protein protein. 112 9e-25
BC017342-1|AAH17342.1| 283|Homo sapiens CDK10 protein protein. 112 9e-25
AJ010341-1|CAB37619.1| 360|Homo sapiens cyclin-dependent kinase... 112 9e-25
Z84480-1|CAI20520.1| 502|Homo sapiens cell division cycle 2-lik... 111 2e-24
BC037289-1|AAH37289.1| 502|Homo sapiens CDC2L6 protein protein. 111 2e-24
BC024247-1|AAH24247.1| 502|Homo sapiens CDC2L6 protein protein. 111 2e-24
AY028424-1|AAK27731.1| 502|Homo sapiens death-preventing kinase... 111 2e-24
AL603914-4|CAI41175.1| 502|Homo sapiens cell division cycle 2-l... 111 2e-24
AL603914-3|CAI41173.1| 251|Homo sapiens cell division cycle 2-l... 111 2e-24
AL603914-2|CAI41172.1| 442|Homo sapiens cell division cycle 2-l... 111 2e-24
AL512430-4|CAI40286.1| 502|Homo sapiens cell division cycle 2-l... 111 2e-24
AL512430-2|CAI40283.1| 251|Homo sapiens cell division cycle 2-l... 111 2e-24
AL512430-1|CAI40282.1| 442|Homo sapiens cell division cycle 2-l... 111 2e-24
AL353572-4|CAM17657.1| 346|Homo sapiens cell cycle related kina... 111 2e-24
AF547664-1|AAN28684.1| 346|Homo sapiens cell cycle related kina... 111 2e-24
AB028951-1|BAA82980.2| 501|Homo sapiens KIAA1028 protein protein. 111 2e-24
X85753-1|CAA59754.1| 464|Homo sapiens CDK8 protein kinase protein. 111 3e-24
BC107601-1|AAI07602.1| 463|Homo sapiens cyclin-dependent kinase... 111 3e-24
BC105950-1|AAI05951.1| 463|Homo sapiens cyclin-dependent kinase... 111 3e-24
BC104492-1|AAI04493.1| 464|Homo sapiens cyclin-dependent kinase... 111 3e-24
BC069634-1|AAH69634.1| 463|Homo sapiens cyclin-dependent kinase... 111 3e-24
AL590108-1|CAH72300.1| 464|Homo sapiens cyclin-dependent kinase... 111 3e-24
AL159159-1|CAI16960.1| 464|Homo sapiens cyclin-dependent kinase... 111 3e-24
X80230-1|CAA56516.1| 372|Homo sapiens serine/threonine protein ... 110 5e-24
L25676-1|AAA35668.1| 372|Homo sapiens CDC2-related kinase protein. 110 5e-24
BC038807-1|AAH38807.1| 349|Homo sapiens ALS2CR7 protein protein. 110 5e-24
BC001968-1|AAH01968.1| 372|Homo sapiens cyclin-dependent kinase... 110 5e-24
AL162586-9|CAI39768.1| 372|Homo sapiens cyclin-dependent kinase... 110 5e-24
AF517840-1|AAM54039.1| 372|Homo sapiens cyclin-dependent kinase... 110 5e-24
AF255306-1|AAF72183.1| 372|Homo sapiens protein kinase CDK9 pro... 110 5e-24
AC007242-1|AAX93182.1| 301|Homo sapiens unknown protein. 110 5e-24
AB053308-1|BAB69017.1| 384|Homo sapiens ALS2CR7 protein. 110 5e-24
U07705-1|AAA19595.1| 775|Homo sapiens PITSLRE isoform PBETA22 p... 109 1e-23
U07704-1|AAA19594.1| 777|Homo sapiens PITSLRE isoform PBETA21 p... 109 1e-23
U04819-1|AAA19585.1| 439|Homo sapiens PITSLRE beta 1 protein. 109 1e-23
M88563-1|AAB59449.1| 446|Homo sapiens p58 protein kinase protein. 109 1e-23
BT019903-1|AAV38706.1| 372|Homo sapiens cyclin-dependent kinase... 109 1e-23
BC110905-1|AAI10906.1| 397|Homo sapiens cell division cycle 2-l... 109 1e-23
BC094827-1|AAH94827.1| 475|Homo sapiens CDC2L2 protein protein. 109 1e-23
BC014464-1|AAH14464.1| 464|Homo sapiens CDC2L2 protein protein. 109 1e-23
AL031282-7|CAI20033.1| 770|Homo sapiens cell division cycle 2-l... 109 1e-23
AL031282-6|CAI20032.1| 783|Homo sapiens cell division cycle 2-l... 109 1e-23
AL031282-5|CAI20034.1| 780|Homo sapiens cell division cycle 2-l... 109 1e-23
AL031282-4|CAI20031.1| 779|Homo sapiens cell division cycle 2-l... 109 1e-23
AL031282-3|CAI20030.1| 746|Homo sapiens cell division cycle 2-l... 109 1e-23
AF080694-4|AAC95300.1| 768|Homo sapiens PITSLRE protein kinase ... 109 1e-23
AF080694-3|AAC95298.1| 781|Homo sapiens PITSLRE protein kinase ... 109 1e-23
AF080694-2|AAC95297.1| 777|Homo sapiens PITSLRE protein kinase ... 109 1e-23
AF080694-1|AAC95299.1| 778|Homo sapiens PITSLRE protein kinase ... 109 1e-23
AF067523-1|AAC72088.1| 397|Homo sapiens PITSLRE protein kinase ... 109 1e-23
AF067522-1|AAC72087.1| 780|Homo sapiens PITSLRE protein kinase ... 109 1e-23
AF067521-1|AAC72086.1| 767|Homo sapiens PITSLRE protein kinase ... 109 1e-23
AF067520-1|AAC72085.1| 776|Homo sapiens PITSLRE protein kinase ... 109 1e-23
AF067519-1|AAC72084.1| 777|Homo sapiens PITSLRE protein kinase ... 109 1e-23
AF067518-1|AAC72083.1| 397|Homo sapiens PITSLRE protein kinase ... 109 1e-23
U04824-1|AAA19586.1| 779|Homo sapiens PITSLRE alpha 2-1 protein. 107 3e-23
U04818-1|AAA19584.1| 562|Homo sapiens PITSLRE alpha 2-4 protein. 107 3e-23
U04817-1|AAA19583.1| 768|Homo sapiens PITSLRE alpha 2-3 protein. 107 3e-23
U04816-1|AAA19582.1| 777|Homo sapiens PITSLRE alpha 2-2 protein. 107 3e-23
U04815-1|AAA19581.1| 461|Homo sapiens PITSLRE alpha 1 protein. 107 3e-23
M37712-1|AAA36406.1| 439|Homo sapiens p58/GTA protein kinase pr... 107 3e-23
BC139777-1|AAI39778.1| 542|Homo sapiens CDC2L2 protein protein. 107 3e-23
BC062579-1|AAH62579.1| 475|Homo sapiens CDC2L2 protein protein. 107 3e-23
BC033069-1|AAH33069.1| 508|Homo sapiens CDC2L1 protein protein. 107 3e-23
AF080683-5|AAC83666.1| 565|Homo sapiens PITSLRE protein kinase ... 107 3e-23
AF080683-4|AAC83663.1| 738|Homo sapiens PITSLRE protein kinase ... 107 3e-23
AF080683-3|AAC83665.1| 748|Homo sapiens PITSLRE protein kinase ... 107 3e-23
AF080683-2|AAC83662.1| 782|Homo sapiens PITSLRE protein kinase ... 107 3e-23
AF080683-1|AAC83664.1| 755|Homo sapiens PITSLRE protein kinase ... 107 3e-23
AF067517-1|AAC72082.1| 565|Homo sapiens PITSLRE protein kinase ... 107 3e-23
AF067516-1|AAC72081.1| 748|Homo sapiens PITSLRE protein kinase ... 107 3e-23
AF067515-1|AAC72080.1| 795|Homo sapiens PITSLRE protein kinase ... 107 3e-23
AF067514-1|AAC72079.1| 737|Homo sapiens PITSLRE protein kinase ... 107 3e-23
AF067513-1|AAC72078.1| 526|Homo sapiens PITSLRE protein kinase ... 107 3e-23
AF067512-1|AAC72077.1| 782|Homo sapiens PITSLRE protein kinase ... 107 3e-23
L33801-1|AAA66475.1| 420|Homo sapiens protein kinase protein. 107 3e-23
CR536510-1|CAG38748.1| 420|Homo sapiens GSK3B protein. 107 3e-23
BC012760-1|AAH12760.1| 420|Homo sapiens GSK3B protein protein. 107 3e-23
BC000251-1|AAH00251.1| 433|Homo sapiens glycogen synthase kinas... 107 3e-23
L40027-1|AAA62432.1| 483|Homo sapiens glycogen synthase kinase ... 107 5e-23
D63424-1|BAA23608.1| 483|Homo sapiens glycogen synthase kinase ... 107 5e-23
BC051865-1|AAH51865.1| 483|Homo sapiens glycogen synthase kinas... 107 5e-23
BC040529-1|AAH40529.1| 231|Homo sapiens PCTK3 protein protein. 107 5e-23
BC027984-1|AAH27984.1| 483|Homo sapiens glycogen synthase kinas... 107 5e-23
AC006486-1|AAD11986.1| 483|Homo sapiens KG3A_HUMAN protein. 107 5e-23
AY994058-1|AAY44299.1| 254|Homo sapiens extracellular regulated... 105 2e-22
AY065978-1|AAL40897.1| 544|Homo sapiens extracellular signal-re... 104 2e-22
Z11695-1|CAA77753.1| 348|Homo sapiens 40kDa protein kinase prot... 103 6e-22
Z11694-1|CAA77752.1| 360|Homo sapiens 41kD protein kinase protein. 103 6e-22
M84489-1|AAA58459.1| 360|Homo sapiens protein kinase 2 protein. 103 6e-22
DQ508104-1|ABF47102.1| 360|Homo sapiens mitogen-activated prote... 103 6e-22
BC017832-1|AAH17832.1| 360|Homo sapiens mitogen-activated prote... 103 6e-22
Z11696-1|CAA77754.1| 355|Homo sapiens 44kDa protein kinase prot... 102 1e-21
M84490-1|AAA36142.1| 366|Homo sapiens kinase 1 protein. 102 1e-21
BX537897-1|CAD97888.1| 323|Homo sapiens hypothetical protein pr... 102 1e-21
BC013992-1|AAH13992.1| 379|Homo sapiens mitogen-activated prote... 102 1e-21
AF174497-1|AAF36538.1| 565|Homo sapiens GR AF-1 coactivator 3 p... 102 1e-21
DQ316259-1|ABC40748.1| 516|Homo sapiens nemo like kinase protein. 101 2e-21
BC099905-1|AAH99905.1| 360|Homo sapiens mitogen-activated prote... 101 2e-21
BC064663-1|AAH64663.1| 515|Homo sapiens nemo-like kinase protein. 101 2e-21
AF197898-1|AAF04857.1| 515|Homo sapiens nemo-like kinase protein. 101 2e-21
AF180819-1|AAD56013.1| 515|Homo sapiens LAK1 protein protein. 101 2e-21
X60188-1|CAA42744.1| 379|Homo sapiens protein serine/threonine ... 100 4e-21
AY033608-1|AAK52330.1| 335|Homo sapiens extracellular signal-re... 100 4e-21
AY033607-1|AAK52329.1| 357|Homo sapiens extracellular signal-re... 100 4e-21
BC053536-1|AAH53536.1| 231|Homo sapiens RAGE protein protein. 99 1e-20
AB022694-1|BAA81688.1| 419|Homo sapiens MOK protein kinase prot... 99 1e-20
AK131512-1|BAD18656.1| 345|Homo sapiens protein ( Homo sapiens ... 97 4e-20
Z95152-5|CAO03649.1| 360|Homo sapiens mitogen-activated protein... 97 5e-20
Y14440-1|CAA74792.1| 364|Homo sapiens stress activated protein ... 97 5e-20
U92268-1|AAB66313.1| 364|Homo sapiens mitogen activated protein... 97 5e-20
U53442-1|AAB05036.1| 372|Homo sapiens p38Beta MAP kinase protein. 97 5e-20
U19775-1|AAC50329.1| 297|Homo sapiens Mxi2 protein. 97 5e-20
L35264-1|AAA57456.1| 360|Homo sapiens CSaids binding protein pr... 97 5e-20
L35263-1|AAA57455.1| 360|Homo sapiens CSaids binding protein pr... 97 5e-20
L35253-1|AAA74301.1| 360|Homo sapiens MAP kinase protein. 97 5e-20
DQ279722-1|ABB72677.1| 364|Homo sapiens mitogen-activated prote... 97 5e-20
CR536505-1|CAG38743.1| 360|Homo sapiens MAPK14 protein. 97 5e-20
CR456514-1|CAG30400.1| 364|Homo sapiens MAPK11 protein. 97 5e-20
BT006933-1|AAP35579.1| 360|Homo sapiens mitogen-activated prote... 97 5e-20
BC031574-1|AAH31574.1| 360|Homo sapiens mitogen-activated prote... 97 5e-20
BC027933-1|AAH27933.1| 364|Homo sapiens mitogen-activated prote... 97 5e-20
BC000092-1|AAH00092.1| 360|Homo sapiens mitogen-activated prote... 97 5e-20
AL022328-13|CAB51539.1| 364|Homo sapiens mitogen-activated prot... 97 5e-20
AF100544-1|AAF36770.1| 360|Homo sapiens stress-activated protei... 97 5e-20
AF031135-1|AAC12714.1| 364|Homo sapiens p38beta2 MAP kinase pro... 97 5e-20
AF001174-1|AAC51373.1| 364|Homo sapiens p38beta2 MAP kinase pro... 97 5e-20
AF001008-1|AAC51250.1| 364|Homo sapiens p38Beta2 MAP Kinase pro... 97 5e-20
AB074150-1|BAB85654.1| 307|Homo sapiens Alternative spliced var... 97 5e-20
X80692-1|CAA56709.1| 721|Homo sapiens p97mapk protein. 96 8e-20
L77964-1|AAA98769.1| 721|Homo sapiens ERK3 protein kinase protein. 96 8e-20
BC035492-1|AAH35492.1| 721|Homo sapiens mitogen-activated prote... 96 8e-20
AF420474-1|AAL17605.1| 721|Homo sapiens ERK-3 protein. 96 8e-20
BC028034-1|AAH28034.1| 277|Homo sapiens MAPK15 protein protein. 95 3e-19
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 94 3e-19
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 94 3e-19
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 94 3e-19
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 94 3e-19
U29727-1|AAA82933.1| 816|Homo sapiens BMK1 gamma kinase protein. 93 8e-19
U29726-1|AAA82932.1| 816|Homo sapiens BMK1 beta kinase protein. 93 8e-19
U29725-1|AAA82931.1| 816|Homo sapiens BMK1 alpha kinase protein. 93 8e-19
U25278-1|AAA81381.1| 815|Homo sapiens ERK5 protein. 93 8e-19
BC030134-1|AAH30134.1| 816|Homo sapiens mitogen-activated prote... 93 8e-19
BC009963-1|AAH09963.1| 816|Homo sapiens mitogen-activated prote... 93 8e-19
BC007992-1|AAH07992.1| 677|Homo sapiens mitogen-activated prote... 93 8e-19
BC007404-1|AAH07404.1| 677|Homo sapiens mitogen-activated prote... 93 8e-19
AY534741-1|AAS38577.1| 533|Homo sapiens mitogen activated prote... 93 8e-19
AB209611-1|BAD92848.1| 453|Homo sapiens Mitogen activated prote... 93 8e-19
Y10487-1|CAA71511.1| 367|Homo sapiens stress-activated protein ... 93 1e-18
U66243-1|AAB40118.1| 367|Homo sapiens p38gamma MAP Kinase protein. 93 1e-18
BC015741-1|AAH15741.1| 367|Homo sapiens mitogen-activated prote... 93 1e-18
AL022328-12|CAB51538.1| 367|Homo sapiens mitogen-activated prot... 93 1e-18
X59727-1|CAA42411.1| 557|Homo sapiens 63kDa protein kinase prot... 92 1e-18
BC117216-1|AAI17217.1| 587|Homo sapiens mitogen-activated prote... 92 1e-18
X79483-1|CAA55984.1| 367|Homo sapiens extracellular signal regu... 92 2e-18
AK222922-1|BAD96642.1| 307|Homo sapiens MAPK13 protein (Fragmen... 92 2e-18
Z95152-2|CAB08438.1| 365|Homo sapiens mitogen-activated protein... 91 2e-18
Y10488-1|CAA71512.1| 365|Homo sapiens stress-activated protein ... 91 2e-18
U93232-1|AAB87639.1| 365|Homo sapiens MAP kinase p38delta protein. 91 2e-18
CR541687-1|CAG46488.1| 365|Homo sapiens MAPK13 protein. 91 2e-18
CR536490-1|CAG38729.1| 365|Homo sapiens MAPK13 protein. 91 2e-18
BT007221-1|AAP35885.1| 365|Homo sapiens mitogen-activated prote... 91 2e-18
BC004428-1|AAH04428.1| 365|Homo sapiens mitogen-activated prote... 91 2e-18
BC001641-1|AAH01641.1| 365|Homo sapiens mitogen-activated prote... 91 2e-18
BC000433-1|AAH00433.1| 365|Homo sapiens mitogen-activated prote... 91 2e-18
AF100546-1|AAF36772.1| 365|Homo sapiens stress-activated protei... 91 2e-18
AF092535-1|AAD23377.1| 365|Homo sapiens mitogen-activated prote... 91 2e-18
AF004709-1|AAC51374.1| 365|Homo sapiens stress-activated protei... 91 2e-18
BC050299-1|AAH50299.1| 587|Homo sapiens mitogen-activated prote... 91 3e-18
AF015256-1|AAC51758.1| 365|Homo sapiens p38 mitogen-activated p... 91 3e-18
U35003-1|AAC50609.1| 424|Homo sapiens JNK2 beta2 protein kinase... 88 3e-17
U35002-1|AAC50608.1| 382|Homo sapiens JNK2 beta1 protein kinase... 88 3e-17
BC133039-1|AAI33040.1| 1001|Homo sapiens TAO kinase 1 protein. 88 3e-17
AY049015-1|AAL12217.1| 1001|Homo sapiens serine/threonine kinase... 88 3e-17
AF263312-1|AAG38502.1| 1001|Homo sapiens STE20-like kinase protein. 88 3e-17
AB037782-1|BAA92599.1| 1005|Homo sapiens KIAA1361 protein protein. 88 3e-17
U35005-1|AAC50611.1| 427|Homo sapiens JNK1 beta2 protein kinase... 87 5e-17
U35004-1|AAC50610.1| 384|Homo sapiens JNK1 beta1 protein kinase... 87 5e-17
U34821-1|AAC50606.1| 382|Homo sapiens JNK2 alpha1 protein kinas... 87 5e-17
U09759-1|AAA74740.1| 424|Homo sapiens protein kinase protein. 87 5e-17
L31951-1|AAA56831.1| 424|Homo sapiens protein kinase protein. 87 5e-17
DQ066599-1|AAY46156.1| 424|Homo sapiens mitogen-activated prote... 87 5e-17
CR536580-1|CAG38817.1| 424|Homo sapiens MAPK9 protein. 87 5e-17
BC130572-1|AAI30573.1| 427|Homo sapiens mitogen-activated prote... 87 5e-17
BC130570-1|AAI30571.1| 427|Homo sapiens mitogen-activated prote... 87 5e-17
BC032539-1|AAH32539.1| 424|Homo sapiens mitogen-activated prote... 87 5e-17
U34820-1|AAC50605.1| 422|Homo sapiens JNK3 alpha1 protein kinas... 87 7e-17
U34819-1|AAC50604.1| 464|Homo sapiens JNK3 alpha2 protein kinas... 87 7e-17
U07620-1|AAC50101.1| 422|Homo sapiens MAP kinase protein. 87 7e-17
BC151221-1|AAI51222.1| 1235|Homo sapiens TAO kinase 2 protein. 87 7e-17
BC142663-1|AAI42664.1| 1235|Homo sapiens TAO kinase 2 protein. 87 7e-17
BC065516-1|AAH65516.1| 319|Homo sapiens MAPK10 protein protein. 87 7e-17
BC051798-1|AAH51798.1| 1426|Homo sapiens TAOK2 protein protein. 87 7e-17
BC035057-1|AAH35057.1| 464|Homo sapiens MAPK10 protein protein. 87 7e-17
BC031825-1|AAH31825.1| 560|Homo sapiens TAOK2 protein protein. 87 7e-17
BC015204-1|AAH15204.1| 762|Homo sapiens Unknown (protein for IM... 87 7e-17
AF263313-1|AAG38503.1| 1049|Homo sapiens STE20-like kinase protein. 87 7e-17
AF061943-1|AAD45616.1| 1235|Homo sapiens prostate derived STE20-... 87 7e-17
AB020688-1|BAA74904.2| 1064|Homo sapiens KIAA0881 protein protein. 87 7e-17
BC051731-1|AAH51731.1| 319|Homo sapiens MAPK10 protein protein. 86 9e-17
U34822-1|AAC50607.1| 427|Homo sapiens JNK1 alpha2 protein kinas... 86 1e-16
L26318-1|AAA36131.1| 384|Homo sapiens protein kinase protein. 86 1e-16
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 85 3e-16
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 85 3e-16
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 85 3e-16
AB012305-1|BAA32794.1| 264|Homo sapiens d-HSCDK2 protein. 85 3e-16
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 84 5e-16
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 84 5e-16
Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein. 83 6e-16
BT007185-1|AAP35849.1| 898|Homo sapiens STE20-like kinase protein. 83 6e-16
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 83 6e-16
BC002756-1|AAH02756.1| 898|Homo sapiens TAO kinase 3 protein. 83 6e-16
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 83 6e-16
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 83 6e-16
AF181985-1|AAF25817.1| 898|Homo sapiens serine/threonine kinase... 83 6e-16
AF179867-1|AAF14559.1| 898|Homo sapiens STE20-like kinase protein. 83 6e-16
AF135158-1|AAG09131.1| 898|Homo sapiens serine kinase protein. 83 6e-16
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 83 6e-16
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 83 8e-16
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 83 8e-16
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 83 8e-16
DQ354583-1|ABC86794.1| 385|Homo sapiens casein kinase 2 alpha i... 82 1e-15
Y12735-1|CAA73266.2| 588|Homo sapiens Dyrk3 protein protein. 82 2e-15
AY590695-1|AAT06103.1| 588|Homo sapiens dual-specificity tyrosi... 82 2e-15
AL591846-9|CAI13541.1| 568|Homo sapiens dual-specificity tyrosi... 82 2e-15
AL591846-7|CAI13539.1| 588|Homo sapiens dual-specificity tyrosi... 82 2e-15
AF327561-1|AAK16443.1| 568|Homo sapiens dual-specificity tyrosi... 82 2e-15
AF186774-1|AAG17029.1| 568|Homo sapiens regulatory erythroid ki... 82 2e-15
AF186773-1|AAG17028.1| 588|Homo sapiens regulatory erythroid ki... 82 2e-15
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 81 3e-15
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 81 3e-15
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 81 3e-15
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 81 3e-15
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 81 3e-15
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 81 3e-15
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 81 3e-15
M55268-1|AAA51548.1| 350|Homo sapiens casein kinase II alpha' s... 81 3e-15
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 81 3e-15
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 81 3e-15
BC008812-1|AAH08812.1| 350|Homo sapiens casein kinase 2, alpha ... 81 3e-15
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 81 3e-15
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 81 3e-15
S53149-1|ABB72474.1| 391|Homo sapiens casein kinase II-alpha su... 81 4e-15
M55265-1|AAA35503.1| 391|Homo sapiens casein kinase II alpha su... 81 4e-15
J02853-1|AAA56821.1| 391|Homo sapiens casein kinase II alpha su... 81 4e-15
BT019792-1|AAV38595.1| 391|Homo sapiens casein kinase 2, alpha ... 81 4e-15
BC071167-1|AAH71167.1| 391|Homo sapiens casein kinase 2, alpha ... 81 4e-15
BC053532-1|AAH53532.1| 391|Homo sapiens casein kinase 2, alpha ... 81 4e-15
BC050036-1|AAH50036.1| 397|Homo sapiens CSNK2A1 protein protein. 81 4e-15
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 81 4e-15
BC015501-1|AAH15501.1| 568|Homo sapiens dual-specificity tyrosi... 81 4e-15
BC011668-1|AAH11668.1| 391|Homo sapiens casein kinase 2, alpha ... 81 4e-15
AL049761-3|CAB65624.1| 391|Homo sapiens casein kinase 2, alpha ... 81 4e-15
X70251-1|CAA49758.1| 391|Homo sapiens casein kinase II alpha su... 80 6e-15
AY112721-1|AAM52224.1| 391|Homo sapiens casein kinase II alpha ... 80 6e-15
U48736-1|AAB03268.1| 496|Homo sapiens serine/threonine-protein ... 80 8e-15
BC034969-1|AAH34969.1| 1007|Homo sapiens PRP4 pre-mRNA processin... 80 8e-15
BC009844-1|AAH09844.1| 496|Homo sapiens PRPF4B protein protein. 80 8e-15
AY029347-1|AAK38155.1| 1007|Homo sapiens serine/threonine-protei... 80 8e-15
AL138831-3|CAI20480.1| 1007|Homo sapiens PRP4 pre-mRNA processin... 80 8e-15
AL049761-2|CAM28336.1| 255|Homo sapiens casein kinase 2, alpha ... 80 8e-15
AL033383-1|CAI42121.1| 1007|Homo sapiens PRP4 pre-mRNA processin... 80 8e-15
AF283465-1|AAM19101.1| 1007|Homo sapiens PRP4 kinase protein. 80 8e-15
AF263311-1|AAG38501.1| 898|Homo sapiens STE20-like kinase protein. 80 8e-15
AB011108-1|BAA25462.1| 1028|Homo sapiens KIAA0536 protein protein. 80 8e-15
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 79 1e-14
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 79 1e-14
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 79 1e-14
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 79 1e-14
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 79 1e-14
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 79 1e-14
S67448-1|AAD13991.1| 89|Homo sapiens CDK4 protein. 79 2e-14
BX538081-1|CAD98005.1| 303|Homo sapiens hypothetical protein pr... 79 2e-14
BC018645-1|AAH18645.1| 400|Homo sapiens mitogen-activated prote... 79 2e-14
BC000471-1|AAH00471.1| 400|Homo sapiens mitogen-activated prote... 79 2e-14
AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle prefere... 78 3e-14
AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein. 78 3e-14
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 77 4e-14
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 77 4e-14
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 77 4e-14
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 77 4e-14
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 77 4e-14
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 77 4e-14
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 77 4e-14
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 77 4e-14
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 77 6e-14
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 77 6e-14
DQ411039-1|ABD66016.1| 260|Homo sapiens protein kinase CDK5 spl... 77 6e-14
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 77 6e-14
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 77 6e-14
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 77 6e-14
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 77 6e-14
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 77 6e-14
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 77 6e-14
Y13493-1|CAA73885.1| 528|Homo sapiens protein kinase Dyrk2 prot... 76 1e-13
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 76 1e-13
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 76 1e-13
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 76 1e-13
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 76 1e-13
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 76 1e-13
BC006375-1|AAH06375.1| 601|Homo sapiens DYRK2 protein protein. 76 1e-13
BC005809-1|AAH05809.1| 528|Homo sapiens dual-specificity tyrosi... 76 1e-13
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 76 1e-13
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 76 1e-13
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 76 1e-13
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 76 1e-13
BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein. 76 1e-13
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 76 1e-13
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 76 1e-13
AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens ... 76 1e-13
AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens ... 76 1e-13
AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein. 76 1e-13
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 76 1e-13
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 76 1e-13
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 75 2e-13
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 75 2e-13
U07358-1|AAA67343.1| 859|Homo sapiens serine/threonine protein ... 75 2e-13
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 75 2e-13
BC050050-1|AAH50050.1| 567|Homo sapiens MAP3K12 protein protein. 75 2e-13
BC035596-1|AAH35596.1| 681|Homo sapiens PAK6 protein protein. 75 2e-13
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 75 2e-13
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 75 2e-13
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 75 2e-13
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 75 2e-13
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 75 2e-13
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 75 2e-13
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 75 2e-13
AJ236915-1|CAC18720.1| 681|Homo sapiens pak5 protein protein. 75 2e-13
AF283475-1|AAL67158.1| 859|Homo sapiens zipper protein kinase p... 75 2e-13
AF276893-1|AAF82800.1| 681|Homo sapiens p21-activated protein k... 75 2e-13
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 75 2e-13
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 75 2e-13
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 75 2e-13
L05624-1|AAA36318.1| 393|Homo sapiens MAP kinase kinase protein. 75 2e-13
CR456515-1|CAG30401.1| 357|Homo sapiens MAPK12 protein. 75 2e-13
BX640648-1|CAE45794.1| 319|Homo sapiens hypothetical protein pr... 75 2e-13
BC139729-1|AAI39730.1| 393|Homo sapiens mitogen-activated prote... 75 2e-13
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 75 2e-13
AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing ... 75 2e-13
U77129-1|AAB48435.1| 846|Homo sapiens KHS1 protein. 75 3e-13
BC036013-1|AAH36013.1| 846|Homo sapiens mitogen-activated prote... 75 3e-13
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 74 4e-13
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 74 5e-13
AL732423-2|CAM17478.1| 788|Homo sapiens mitogen-activated prote... 74 5e-13
AL732423-1|CAM17479.1| 748|Homo sapiens mitogen-activated prote... 74 5e-13
AL732326-2|CAM23143.1| 788|Homo sapiens mitogen-activated prote... 74 5e-13
AL732326-1|CAM23142.1| 748|Homo sapiens mitogen-activated prote... 74 5e-13
AK131412-1|BAD18559.1| 748|Homo sapiens protein ( Homo sapiens ... 74 5e-13
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 73 7e-13
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 73 7e-13
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 73 7e-13
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 73 7e-13
Z95152-3|CAI19690.1| 355|Homo sapiens mitogen-activated protein... 73 9e-13
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 73 9e-13
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 73 9e-13
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 73 9e-13
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 73 9e-13
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 73 9e-13
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 73 9e-13
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 73 9e-13
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 73 9e-13
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 73 9e-13
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 73 9e-13
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 73 9e-13
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 73 9e-13
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 73 9e-13
D88357-1|BAA26001.1| 240|Homo sapiens CDC2 delta T protein. 73 1e-12
CR542222-1|CAG47018.1| 306|Homo sapiens NEK6 protein. 73 1e-12
CR457091-1|CAG33372.1| 306|Homo sapiens NEK6 protein. 73 1e-12
BC024179-1|AAH24179.1| 719|Homo sapiens p21(CDKN1A)-activated k... 73 1e-12
BC012761-1|AAH12761.1| 313|Homo sapiens NIMA (never in mitosis ... 73 1e-12
BC004209-1|AAH04209.2| 313|Homo sapiens NEK6 protein protein. 73 1e-12
BC004174-1|AAH04174.2| 313|Homo sapiens NEK6 protein protein. 73 1e-12
BC000101-1|AAH00101.2| 313|Homo sapiens NEK6 protein protein. 73 1e-12
AL353612-1|CAI23529.1| 719|Homo sapiens p21(CDKN1A)-activated k... 73 1e-12
AL162724-9|CAH70254.1| 313|Homo sapiens NIMA (never in mitosis ... 73 1e-12
AL162724-8|CAH70253.1| 201|Homo sapiens NIMA (never in mitosis ... 73 1e-12
AL162724-2|CAH70247.1| 347|Homo sapiens NIMA (never in mitosis ... 73 1e-12
AL137846-13|CAI10883.1| 313|Homo sapiens NIMA (never in mitosis... 73 1e-12
AL137846-12|CAI10882.1| 201|Homo sapiens NIMA (never in mitosis... 73 1e-12
AL137846-6|CAI10876.1| 347|Homo sapiens NIMA (never in mitosis ... 73 1e-12
AL135935-1|CAH71126.1| 719|Homo sapiens p21(CDKN1A)-activated k... 73 1e-12
AL031652-1|CAI42211.1| 719|Homo sapiens p21(CDKN1A)-activated k... 73 1e-12
AF087909-1|AAG13417.1| 338|Homo sapiens NIMA-related kinase 6 p... 73 1e-12
AB040812-1|BAA94194.1| 719|Homo sapiens protein kinase PAK5 pro... 73 1e-12
AB033090-1|BAA86578.1| 753|Homo sapiens KIAA1264 protein protein. 73 1e-12
AB026289-1|BAA85045.1| 306|Homo sapiens protein kinase SID6-151... 73 1e-12
DQ234352-1|ABB29981.1| 308|Homo sapiens mitogen-activated prote... 72 2e-12
BC047696-1|AAH47696.1| 414|Homo sapiens serine/threonine kinase... 72 2e-12
BC023508-1|AAH23508.2| 414|Homo sapiens serine/threonine kinase... 72 2e-12
AB011420-1|BAA34126.1| 414|Homo sapiens DRAK1 protein. 72 2e-12
U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kin... 72 2e-12
U22512-1|AAC50713.1| 714|Homo sapiens CHUK protein. 72 2e-12
CR542225-1|CAG47021.1| 372|Homo sapiens STK17B protein. 72 2e-12
CR542210-1|CAG47006.1| 372|Homo sapiens STK17B protein. 72 2e-12
BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activate... 72 2e-12
BC092514-1|AAH92514.1| 745|Homo sapiens conserved helix-loop-he... 72 2e-12
BC034501-1|AAH34501.1| 616|Homo sapiens homeodomain interacting... 72 2e-12
BC016040-1|AAH16040.1| 372|Homo sapiens serine/threonine kinase... 72 2e-12
AY652653-1|AAT49098.1| 745|Homo sapiens conserved helix-loop-he... 72 2e-12
AL138921-4|CAH72401.1| 745|Homo sapiens conserved helix-loop-he... 72 2e-12
AK057380-1|BAB71458.1| 541|Homo sapiens protein ( Homo sapiens ... 72 2e-12
AF080157-1|AAD08996.1| 745|Homo sapiens IkB kinase-a protein. 72 2e-12
AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B... 72 2e-12
>X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein
kinase protein.
Length = 358
Score = 231 bits (566), Expect = 1e-60
Identities = 101/135 (74%), Positives = 115/135 (85%), Gaps = 1/135 (0%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
L NL+EVFRRKR+LHLVFEYCDHTVLHEL++Y G PE L K I WQTLQ V +CH+HNC
Sbjct: 64 LVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNC 123
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYSTP 598
IHRDVKPENIL+T V+KLCDFGFAR+++ P + YTDYVATRWYR+PELLVGDT Y P
Sbjct: 124 IHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPP 183
Query: 599 VDVWAIXCVFAELLT 643
VDVWAI CVFAELL+
Sbjct: 184 VDVWAIGCVFAELLS 198
Score = 119 bits (286), Expect = 1e-26
Identities = 51/64 (79%), Positives = 62/64 (96%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME+YEK+ K+GEGSYG+V+KCRNRDTG+IVA+KKF+E+EDDP+I+KIALREIRMLK LKH
Sbjct: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
Query: 235 PNLV 246
PNLV
Sbjct: 62 PNLV 65
>BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent
kinase-like 1 (CDC2-related kinase) protein.
Length = 358
Score = 231 bits (566), Expect = 1e-60
Identities = 101/135 (74%), Positives = 115/135 (85%), Gaps = 1/135 (0%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
L NL+EVFRRKR+LHLVFEYCDHTVLHEL++Y G PE L K I WQTLQ V +CH+HNC
Sbjct: 64 LVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNC 123
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYSTP 598
IHRDVKPENIL+T V+KLCDFGFAR+++ P + YTDYVATRWYR+PELLVGDT Y P
Sbjct: 124 IHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPP 183
Query: 599 VDVWAIXCVFAELLT 643
VDVWAI CVFAELL+
Sbjct: 184 VDVWAIGCVFAELLS 198
Score = 119 bits (286), Expect = 1e-26
Identities = 51/64 (79%), Positives = 62/64 (96%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME+YEK+ K+GEGSYG+V+KCRNRDTG+IVA+KKF+E+EDDP+I+KIALREIRMLK LKH
Sbjct: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
Query: 235 PNLV 246
PNLV
Sbjct: 62 PNLV 65
>AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent
kinase-like 1 (CDC2-related kinase) protein.
Length = 358
Score = 231 bits (566), Expect = 1e-60
Identities = 101/135 (74%), Positives = 115/135 (85%), Gaps = 1/135 (0%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
L NL+EVFRRKR+LHLVFEYCDHTVLHEL++Y G PE L K I WQTLQ V +CH+HNC
Sbjct: 64 LVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNC 123
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYSTP 598
IHRDVKPENIL+T V+KLCDFGFAR+++ P + YTDYVATRWYR+PELLVGDT Y P
Sbjct: 124 IHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPP 183
Query: 599 VDVWAIXCVFAELLT 643
VDVWAI CVFAELL+
Sbjct: 184 VDVWAIGCVFAELLS 198
Score = 119 bits (286), Expect = 1e-26
Identities = 51/64 (79%), Positives = 62/64 (96%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME+YEK+ K+GEGSYG+V+KCRNRDTG+IVA+KKF+E+EDDP+I+KIALREIRMLK LKH
Sbjct: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
Query: 235 PNLV 246
PNLV
Sbjct: 62 PNLV 65
>AY847283-1|AAW31760.1| 379|Homo sapiens cyclin-dependent
kinase-like 4 protein.
Length = 379
Score = 227 bits (556), Expect = 2e-59
Identities = 94/136 (69%), Positives = 117/136 (86%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
L NLIEVFRRKRK+HLVFEYCDHT+L+ELE+ P G + + K ++WQTLQ + +CH HNC
Sbjct: 63 LVNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHIHNC 122
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPV 601
IHRD+KPENIL+T G++K+CDFGFA+++ PG++YTDYVATRWYRAPELLVGDT Y + V
Sbjct: 123 IHRDIKPENILITKQGIIKICDFGFAQILIPGDAYTDYVATRWYRAPELLVGDTQYGSSV 182
Query: 602 DVWAIXCVFAELLTSE 649
D+WAI CVFAELLT +
Sbjct: 183 DIWAIGCVFAELLTGQ 198
Score = 115 bits (277), Expect = 1e-25
Identities = 50/64 (78%), Positives = 61/64 (95%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME+YEKLAK GEGSYG+V+KCRN+ +G++VAVKKFVE+EDDP+++KIALREIRMLK LKH
Sbjct: 1 MEKYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKH 60
Query: 235 PNLV 246
PNLV
Sbjct: 61 PNLV 64
>AY845084-1|AAW30008.1| 315|Homo sapiens cyclin-dependent
kinase-like 4 protein.
Length = 315
Score = 227 bits (556), Expect = 2e-59
Identities = 94/136 (69%), Positives = 117/136 (86%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
L NLIEVFRRKRK+HLVFEYCDHT+L+ELE+ P G + + K ++WQTLQ + +CH HNC
Sbjct: 63 LVNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHIHNC 122
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPV 601
IHRD+KPENIL+T G++K+CDFGFA+++ PG++YTDYVATRWYRAPELLVGDT Y + V
Sbjct: 123 IHRDIKPENILITKQGIIKICDFGFAQILIPGDAYTDYVATRWYRAPELLVGDTQYGSSV 182
Query: 602 DVWAIXCVFAELLTSE 649
D+WAI CVFAELLT +
Sbjct: 183 DIWAIGCVFAELLTGQ 198
Score = 115 bits (277), Expect = 1e-25
Identities = 50/64 (78%), Positives = 61/64 (95%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME+YEKLAK GEGSYG+V+KCRN+ +G++VAVKKFVE+EDDP+++KIALREIRMLK LKH
Sbjct: 1 MEKYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKH 60
Query: 235 PNLV 246
PNLV
Sbjct: 61 PNLV 64
>U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinase
protein.
Length = 493
Score = 181 bits (441), Expect = 2e-45
Identities = 78/137 (56%), Positives = 103/137 (75%), Gaps = 1/137 (0%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
L NL+EV ++K++ +LVFE+ DHT+L +LE +P G + ++ ++Q + G+ +CH HN
Sbjct: 63 LVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNI 122
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFAR-MISPGESYTDYVATRWYRAPELLVGDTMYSTP 598
IHRD+KPENIL++ GVVKLCDFGFAR + +PGE YTDYVATRWYRAPELLVGD Y
Sbjct: 123 IHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKA 182
Query: 599 VDVWAIXCVFAELLTSE 649
VDVWAI C+ E+ E
Sbjct: 183 VDVWAIGCLVTEMFMGE 199
Score = 99.5 bits (237), Expect = 9e-21
Identities = 41/64 (64%), Positives = 56/64 (87%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME+YE L +GEGSYG+V KCRN+DTG IVA+KKF+E++DD +++KIA+REI++LK L+H
Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60
Query: 235 PNLV 246
NLV
Sbjct: 61 ENLV 64
>BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent
kinase-like 2 (CDC2-related kinase) protein.
Length = 493
Score = 181 bits (441), Expect = 2e-45
Identities = 78/137 (56%), Positives = 103/137 (75%), Gaps = 1/137 (0%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
L NL+EV ++K++ +LVFE+ DHT+L +LE +P G + ++ ++Q + G+ +CH HN
Sbjct: 63 LVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNI 122
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFAR-MISPGESYTDYVATRWYRAPELLVGDTMYSTP 598
IHRD+KPENIL++ GVVKLCDFGFAR + +PGE YTDYVATRWYRAPELLVGD Y
Sbjct: 123 IHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKA 182
Query: 599 VDVWAIXCVFAELLTSE 649
VDVWAI C+ E+ E
Sbjct: 183 VDVWAIGCLVTEMFMGE 199
Score = 99.5 bits (237), Expect = 9e-21
Identities = 41/64 (64%), Positives = 56/64 (87%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME+YE L +GEGSYG+V KCRN+DTG IVA+KKF+E++DD +++KIA+REI++LK L+H
Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60
Query: 235 PNLV 246
NLV
Sbjct: 61 ENLV 64
>BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent
kinase-like 2 (CDC2-related kinase) protein.
Length = 493
Score = 181 bits (441), Expect = 2e-45
Identities = 78/137 (56%), Positives = 103/137 (75%), Gaps = 1/137 (0%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
L NL+EV ++K++ +LVFE+ DHT+L +LE +P G + ++ ++Q + G+ +CH HN
Sbjct: 63 LVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSHNI 122
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFAR-MISPGESYTDYVATRWYRAPELLVGDTMYSTP 598
IHRD+KPENIL++ GVVKLCDFGFAR + +PGE YTDYVATRWYRAPELLVGD Y
Sbjct: 123 IHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKA 182
Query: 599 VDVWAIXCVFAELLTSE 649
VDVWAI C+ E+ E
Sbjct: 183 VDVWAIGCLVTEMFMGE 199
Score = 99.5 bits (237), Expect = 9e-21
Identities = 41/64 (64%), Positives = 56/64 (87%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME+YE L +GEGSYG+V KCRN+DTG IVA+KKF+E++DD +++KIA+REI++LK L+H
Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60
Query: 235 PNLV 246
NLV
Sbjct: 61 ENLV 64
>BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein.
Length = 592
Score = 177 bits (432), Expect = 2e-44
Identities = 77/135 (57%), Positives = 102/135 (75%), Gaps = 1/135 (0%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
L NLIEVFR+K+K+HLVFE+ DHTVL EL+ Y G ++ ++Q L+ + Y H +N
Sbjct: 62 LVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNI 121
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFAR-MISPGESYTDYVATRWYRAPELLVGDTMYSTP 598
IHRD+KPENIL++ G+ KLCDFGFAR + +PG+ YTDYVATRWYRAPEL++ DT Y P
Sbjct: 122 IHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKP 181
Query: 599 VDVWAIXCVFAELLT 643
VD+WA+ C+ E+ T
Sbjct: 182 VDIWALGCMIIEMAT 196
Score = 75.8 bits (178), Expect = 1e-13
Identities = 35/64 (54%), Positives = 46/64 (71%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME YE L K+GEGSYG V KC++++TG+IVA+K F E + + KIA+REI+ LK H
Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQS-VNKIAMREIKFLKQFHH 59
Query: 235 PNLV 246
NLV
Sbjct: 60 ENLV 63
>AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protein
kinase NKIAMRE protein.
Length = 455
Score = 177 bits (432), Expect = 2e-44
Identities = 77/135 (57%), Positives = 102/135 (75%), Gaps = 1/135 (0%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
L NLIEVFR+K+K+HLVFE+ DHTVL EL+ Y G ++ ++Q L+ + Y H +N
Sbjct: 62 LVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNI 121
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFAR-MISPGESYTDYVATRWYRAPELLVGDTMYSTP 598
IHRD+KPENIL++ G+ KLCDFGFAR + +PG+ YTDYVATRWYRAPEL++ DT Y P
Sbjct: 122 IHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKP 181
Query: 599 VDVWAIXCVFAELLT 643
VD+WA+ C+ E+ T
Sbjct: 182 VDIWALGCMIIEMAT 196
Score = 75.8 bits (178), Expect = 1e-13
Identities = 35/64 (54%), Positives = 46/64 (71%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME YE L K+GEGSYG V KC++++TG+IVA+K F E + + KIA+REI+ LK H
Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQS-VNKIAMREIKFLKQFHH 59
Query: 235 PNLV 246
NLV
Sbjct: 60 ENLV 63
>Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-like
5 protein.
Length = 1030
Score = 149 bits (360), Expect = 1e-35
Identities = 67/141 (47%), Positives = 97/141 (68%), Gaps = 2/141 (1%)
Frame = +2
Query: 221 RT*SIRTLFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVA 400
RT + L E FRR+ KL+LVFEY + +L LE+ P G P K I+Q ++ +
Sbjct: 65 RTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIH 124
Query: 401 YCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGE--SYTDYVATRWYRAPELLV 574
+CH+++ +HRD+KPEN+L++ + V+KLCDFGFAR +S G +YT+YVATRWYR+PELL+
Sbjct: 125 WCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLL 184
Query: 575 GDTMYSTPVDVWAIXCVFAEL 637
G Y VD+W++ C+ EL
Sbjct: 185 G-APYGKSVDMWSVGCILGEL 204
Score = 73.3 bits (172), Expect = 7e-13
Identities = 30/64 (46%), Positives = 50/64 (78%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M ++E L +GEG+YG+V KCR+++T EIVA+KKF ++E++ +++ LRE++ML+ LK
Sbjct: 10 MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQ 69
Query: 235 PNLV 246
N+V
Sbjct: 70 ENIV 73
>Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein.
Length = 1030
Score = 149 bits (360), Expect = 1e-35
Identities = 67/141 (47%), Positives = 97/141 (68%), Gaps = 2/141 (1%)
Frame = +2
Query: 221 RT*SIRTLFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVA 400
RT + L E FRR+ KL+LVFEY + +L LE+ P G P K I+Q ++ +
Sbjct: 65 RTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIH 124
Query: 401 YCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGE--SYTDYVATRWYRAPELLV 574
+CH+++ +HRD+KPEN+L++ + V+KLCDFGFAR +S G +YT+YVATRWYR+PELL+
Sbjct: 125 WCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLL 184
Query: 575 GDTMYSTPVDVWAIXCVFAEL 637
G Y VD+W++ C+ EL
Sbjct: 185 G-APYGKSVDMWSVGCILGEL 204
Score = 73.3 bits (172), Expect = 7e-13
Identities = 30/64 (46%), Positives = 50/64 (78%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M ++E L +GEG+YG+V KCR+++T EIVA+KKF ++E++ +++ LRE++ML+ LK
Sbjct: 10 MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQ 69
Query: 235 PNLV 246
N+V
Sbjct: 70 ENIV 73
>AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase 9
protein.
Length = 1030
Score = 149 bits (360), Expect = 1e-35
Identities = 67/141 (47%), Positives = 97/141 (68%), Gaps = 2/141 (1%)
Frame = +2
Query: 221 RT*SIRTLFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVA 400
RT + L E FRR+ KL+LVFEY + +L LE+ P G P K I+Q ++ +
Sbjct: 65 RTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIH 124
Query: 401 YCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGE--SYTDYVATRWYRAPELLV 574
+CH+++ +HRD+KPEN+L++ + V+KLCDFGFAR +S G +YT+YVATRWYR+PELL+
Sbjct: 125 WCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLL 184
Query: 575 GDTMYSTPVDVWAIXCVFAEL 637
G Y VD+W++ C+ EL
Sbjct: 185 G-APYGKSVDMWSVGCILGEL 204
Score = 73.3 bits (172), Expect = 7e-13
Identities = 30/64 (46%), Positives = 50/64 (78%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M ++E L +GEG+YG+V KCR+++T EIVA+KKF ++E++ +++ LRE++ML+ LK
Sbjct: 10 MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQ 69
Query: 235 PNLV 246
N+V
Sbjct: 70 ENIV 73
>AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent
kinase-like 5 protein.
Length = 1030
Score = 149 bits (360), Expect = 1e-35
Identities = 67/141 (47%), Positives = 97/141 (68%), Gaps = 2/141 (1%)
Frame = +2
Query: 221 RT*SIRTLFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVA 400
RT + L E FRR+ KL+LVFEY + +L LE+ P G P K I+Q ++ +
Sbjct: 65 RTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIH 124
Query: 401 YCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGE--SYTDYVATRWYRAPELLV 574
+CH+++ +HRD+KPEN+L++ + V+KLCDFGFAR +S G +YT+YVATRWYR+PELL+
Sbjct: 125 WCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLL 184
Query: 575 GDTMYSTPVDVWAIXCVFAEL 637
G Y VD+W++ C+ EL
Sbjct: 185 G-APYGKSVDMWSVGCILGEL 204
Score = 73.3 bits (172), Expect = 7e-13
Identities = 30/64 (46%), Positives = 50/64 (78%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M ++E L +GEG+YG+V KCR+++T EIVA+KKF ++E++ +++ LRE++ML+ LK
Sbjct: 10 MNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQ 69
Query: 235 PNLV 246
N+V
Sbjct: 70 ENIV 73
>X66357-1|CAA47001.1| 305|Homo sapiens serine/threonine protein
kinase protein.
Length = 305
Score = 138 bits (333), Expect = 2e-32
Identities = 62/139 (44%), Positives = 90/139 (64%), Gaps = 2/139 (1%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAG-CPELLSKQIIWQTLQGVAYCHRHN 418
+ L++V +RKL+LVFE+ + ++ P P L K ++Q LQGV++CH H
Sbjct: 63 IVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHR 122
Query: 419 CIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYST 595
IHRD+KP+N+L+ G +KL DFG AR P +YT V T WYRAPE+L+G Y+T
Sbjct: 123 VIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTT 182
Query: 596 PVDVWAIXCVFAELLTSEA 652
VD+W+I C+FAE++T +A
Sbjct: 183 AVDIWSIGCIFAEMVTRKA 201
Score = 73.3 bits (172), Expect = 7e-13
Identities = 31/64 (48%), Positives = 49/64 (76%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M+ ++K+ K+GEG+YG+VYK +NR+TG++VA+KK + + + A+REI +LK LKH
Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
Query: 235 PNLV 246
PN+V
Sbjct: 61 PNIV 64
>AY789470-1|AAV40830.1| 305|Homo sapiens cyclin-dependent kinase 3
protein.
Length = 305
Score = 138 bits (333), Expect = 2e-32
Identities = 62/139 (44%), Positives = 90/139 (64%), Gaps = 2/139 (1%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAG-CPELLSKQIIWQTLQGVAYCHRHN 418
+ L++V +RKL+LVFE+ + ++ P P L K ++Q LQGV++CH H
Sbjct: 63 IVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHR 122
Query: 419 CIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYST 595
IHRD+KP+N+L+ G +KL DFG AR P +YT V T WYRAPE+L+G Y+T
Sbjct: 123 VIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTT 182
Query: 596 PVDVWAIXCVFAELLTSEA 652
VD+W+I C+FAE++T +A
Sbjct: 183 AVDIWSIGCIFAEMVTRKA 201
Score = 73.3 bits (172), Expect = 7e-13
Identities = 31/64 (48%), Positives = 49/64 (76%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M+ ++K+ K+GEG+YG+VYK +NR+TG++VA+KK + + + A+REI +LK LKH
Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
Query: 235 PNLV 246
PN+V
Sbjct: 61 PNIV 64
>X61622-1|CAA43807.1| 298|Homo sapiens CDK2 protein.
Length = 298
Score = 136 bits (328), Expect = 9e-32
Identities = 60/139 (43%), Positives = 90/139 (64%), Gaps = 2/139 (1%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYP-AGCPELLSKQIIWQTLQGVAYCHRHN 418
+ L++V + KL+LVFE+ + ++ G P L K ++Q LQG+A+CH H
Sbjct: 63 IVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHR 122
Query: 419 CIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYST 595
+HRD+KP+N+L+ ++G +KL DFG AR P +YT V T WYRAPE+L+G YST
Sbjct: 123 VLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGSKYYST 182
Query: 596 PVDVWAIXCVFAELLTSEA 652
VD+W++ C+FAE++T A
Sbjct: 183 AVDIWSLGCIFAEMVTRRA 201
Score = 73.7 bits (173), Expect = 5e-13
Identities = 32/64 (50%), Positives = 47/64 (73%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME ++K+ K+GEG+YG+VYK RN+ TGE+VA+KK + + + A+REI +LK L H
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 235 PNLV 246
PN+V
Sbjct: 61 PNIV 64
>X62071-1|CAA43985.1| 298|Homo sapiens cdk2 protein.
Length = 298
Score = 134 bits (325), Expect = 2e-31
Identities = 60/139 (43%), Positives = 90/139 (64%), Gaps = 2/139 (1%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYP-AGCPELLSKQIIWQTLQGVAYCHRHN 418
+ L++V + KL+LVFE+ + ++ G P L K ++Q LQG+A+CH H
Sbjct: 63 IVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHR 122
Query: 419 CIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYST 595
+HRD+KP+N+L+ ++G +KL DFG AR P +YT V T WYRAPE+L+G YST
Sbjct: 123 VLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYST 182
Query: 596 PVDVWAIXCVFAELLTSEA 652
VD+W++ C+FAE++T A
Sbjct: 183 AVDIWSLGCIFAEMVTRRA 201
Score = 74.5 bits (175), Expect = 3e-13
Identities = 32/64 (50%), Positives = 47/64 (73%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME ++K+ K+GEG+YG+VYK RN+ TGE+VA+KK + + + A+REI +LK L H
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRXDTETEGVPSTAIREISLLKELNH 60
Query: 235 PNLV 246
PN+V
Sbjct: 61 PNIV 64
>M68520-1|AAA35667.1| 298|Homo sapiens cdc2-related protein kinase
protein.
Length = 298
Score = 134 bits (325), Expect = 2e-31
Identities = 60/139 (43%), Positives = 90/139 (64%), Gaps = 2/139 (1%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYP-AGCPELLSKQIIWQTLQGVAYCHRHN 418
+ L++V + KL+LVFE+ + ++ G P L K ++Q LQG+A+CH H
Sbjct: 63 IVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHR 122
Query: 419 CIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYST 595
+HRD+KP+N+L+ ++G +KL DFG AR P +YT V T WYRAPE+L+G YST
Sbjct: 123 VLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYST 182
Query: 596 PVDVWAIXCVFAELLTSEA 652
VD+W++ C+FAE++T A
Sbjct: 183 AVDIWSLGCIFAEMVTRRA 201
Score = 73.7 bits (173), Expect = 5e-13
Identities = 32/64 (50%), Positives = 47/64 (73%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME ++K+ K+GEG+YG+VYK RN+ TGE+VA+KK + + + A+REI +LK L H
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 235 PNLV 246
PN+V
Sbjct: 61 PNIV 64
>BT006821-1|AAP35467.1| 298|Homo sapiens cyclin-dependent kinase 2
protein.
Length = 298
Score = 134 bits (325), Expect = 2e-31
Identities = 60/139 (43%), Positives = 90/139 (64%), Gaps = 2/139 (1%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYP-AGCPELLSKQIIWQTLQGVAYCHRHN 418
+ L++V + KL+LVFE+ + ++ G P L K ++Q LQG+A+CH H
Sbjct: 63 IVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHR 122
Query: 419 CIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYST 595
+HRD+KP+N+L+ ++G +KL DFG AR P +YT V T WYRAPE+L+G YST
Sbjct: 123 VLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYST 182
Query: 596 PVDVWAIXCVFAELLTSEA 652
VD+W++ C+FAE++T A
Sbjct: 183 AVDIWSLGCIFAEMVTRRA 201
Score = 73.7 bits (173), Expect = 5e-13
Identities = 32/64 (50%), Positives = 47/64 (73%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME ++K+ K+GEG+YG+VYK RN+ TGE+VA+KK + + + A+REI +LK L H
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 235 PNLV 246
PN+V
Sbjct: 61 PNIV 64
>BC035807-1|AAH35807.1| 292|Homo sapiens ICK protein protein.
Length = 292
Score = 134 bits (325), Expect = 2e-31
Identities = 60/131 (45%), Positives = 84/131 (64%)
Frame = +2
Query: 251 LIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
L EV R L+ +FEY + +++ PE + I++Q LQG+A+ H+H HR
Sbjct: 65 LKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHR 124
Query: 431 DVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVW 610
D+KPEN+L +VK+ DFG AR I YTDYV+TRWYRAPE+L+ T YS+P+DVW
Sbjct: 125 DLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSPIDVW 184
Query: 611 AIXCVFAELLT 643
A+ C+ AE+ T
Sbjct: 185 AVGCIMAEVYT 195
Score = 48.0 bits (109), Expect = 3e-05
Identities = 24/64 (37%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M RY + +LG+G+YG V R+ ++GE++A+KK ++ + + LRE++ LK L H
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKK-MKRKFYSWEECMNLREVKSLKKLNH 59
Query: 235 PNLV 246
N+V
Sbjct: 60 ANVV 63
>BC003065-1|AAH03065.1| 298|Homo sapiens cyclin-dependent kinase 2
protein.
Length = 298
Score = 134 bits (325), Expect = 2e-31
Identities = 60/139 (43%), Positives = 90/139 (64%), Gaps = 2/139 (1%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYP-AGCPELLSKQIIWQTLQGVAYCHRHN 418
+ L++V + KL+LVFE+ + ++ G P L K ++Q LQG+A+CH H
Sbjct: 63 IVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHR 122
Query: 419 CIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYST 595
+HRD+KP+N+L+ ++G +KL DFG AR P +YT V T WYRAPE+L+G YST
Sbjct: 123 VLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYST 182
Query: 596 PVDVWAIXCVFAELLTSEA 652
VD+W++ C+FAE++T A
Sbjct: 183 AVDIWSLGCIFAEMVTRRA 201
Score = 73.7 bits (173), Expect = 5e-13
Identities = 32/64 (50%), Positives = 47/64 (73%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME ++K+ K+GEG+YG+VYK RN+ TGE+VA+KK + + + A+REI +LK L H
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 235 PNLV 246
PN+V
Sbjct: 61 PNIV 64
>AL162581-2|CAI19518.1| 632|Homo sapiens RP1-132F22.1 protein.
Length = 632
Score = 134 bits (325), Expect = 2e-31
Identities = 60/131 (45%), Positives = 84/131 (64%)
Frame = +2
Query: 251 LIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
L EV R L+ +FEY + +++ PE + I++Q LQG+A+ H+H HR
Sbjct: 65 LKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHR 124
Query: 431 DVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVW 610
D+KPEN+L +VK+ DFG AR I YTDYV+TRWYRAPE+L+ T YS+P+DVW
Sbjct: 125 DLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSPIDVW 184
Query: 611 AIXCVFAELLT 643
A+ C+ AE+ T
Sbjct: 185 AVGCIMAEVYT 195
Score = 48.0 bits (109), Expect = 3e-05
Identities = 24/64 (37%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M RY + +LG+G+YG V R+ ++GE++A+KK ++ + + LRE++ LK L H
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKK-MKRKFYSWEECMNLREVKSLKKLNH 59
Query: 235 PNLV 246
N+V
Sbjct: 60 ANVV 63
>AL031178-1|CAI20261.1| 632|Homo sapiens RP1-132F22.1 protein.
Length = 632
Score = 134 bits (325), Expect = 2e-31
Identities = 60/131 (45%), Positives = 84/131 (64%)
Frame = +2
Query: 251 LIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
L EV R L+ +FEY + +++ PE + I++Q LQG+A+ H+H HR
Sbjct: 65 LKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHR 124
Query: 431 DVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVW 610
D+KPEN+L +VK+ DFG AR I YTDYV+TRWYRAPE+L+ T YS+P+DVW
Sbjct: 125 DLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSPIDVW 184
Query: 611 AIXCVFAELLT 643
A+ C+ AE+ T
Sbjct: 185 AVGCIMAEVYT 195
Score = 48.0 bits (109), Expect = 3e-05
Identities = 24/64 (37%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M RY + +LG+G+YG V R+ ++GE++A+KK ++ + + LRE++ LK L H
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKK-MKRKFYSWEECMNLREVKSLKKLNH 59
Query: 235 PNLV 246
N+V
Sbjct: 60 ANVV 63
>AF512553-1|AAM34794.1| 298|Homo sapiens cyclin-dependent kinase 2
protein.
Length = 298
Score = 134 bits (325), Expect = 2e-31
Identities = 60/139 (43%), Positives = 90/139 (64%), Gaps = 2/139 (1%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYP-AGCPELLSKQIIWQTLQGVAYCHRHN 418
+ L++V + KL+LVFE+ + ++ G P L K ++Q LQG+A+CH H
Sbjct: 63 IVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHR 122
Query: 419 CIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYST 595
+HRD+KP+N+L+ ++G +KL DFG AR P +YT V T WYRAPE+L+G YST
Sbjct: 123 VLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYST 182
Query: 596 PVDVWAIXCVFAELLTSEA 652
VD+W++ C+FAE++T A
Sbjct: 183 AVDIWSLGCIFAEMVTRRA 201
Score = 73.7 bits (173), Expect = 5e-13
Identities = 32/64 (50%), Positives = 47/64 (73%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME ++K+ K+GEG+YG+VYK RN+ TGE+VA+KK + + + A+REI +LK L H
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 235 PNLV 246
PN+V
Sbjct: 61 PNIV 64
>AF152469-1|AAG43364.1| 632|Homo sapiens MAK-related kinase
protein.
Length = 632
Score = 134 bits (325), Expect = 2e-31
Identities = 60/131 (45%), Positives = 84/131 (64%)
Frame = +2
Query: 251 LIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
L EV R L+ +FEY + +++ PE + I++Q LQG+A+ H+H HR
Sbjct: 65 LKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHR 124
Query: 431 DVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVW 610
D+KPEN+L +VK+ DFG AR I YTDYV+TRWYRAPE+L+ T YS+P+DVW
Sbjct: 125 DLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSPIDVW 184
Query: 611 AIXCVFAELLT 643
A+ C+ AE+ T
Sbjct: 185 AVGCIMAEVYT 195
Score = 48.0 bits (109), Expect = 3e-05
Identities = 24/64 (37%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M RY + +LG+G+YG V R+ ++GE++A+KK ++ + + LRE++ LK L H
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKK-MKRKFYSWEECMNLREVKSLKKLNH 59
Query: 235 PNLV 246
N+V
Sbjct: 60 ANVV 63
>AB023153-1|BAA76780.2| 640|Homo sapiens KIAA0936 protein protein.
Length = 640
Score = 134 bits (325), Expect = 2e-31
Identities = 60/131 (45%), Positives = 84/131 (64%)
Frame = +2
Query: 251 LIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
L EV R L+ +FEY + +++ PE + I++Q LQG+A+ H+H HR
Sbjct: 73 LKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHR 132
Query: 431 DVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVW 610
D+KPEN+L +VK+ DFG AR I YTDYV+TRWYRAPE+L+ T YS+P+DVW
Sbjct: 133 DLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSPIDVW 192
Query: 611 AIXCVFAELLT 643
A+ C+ AE+ T
Sbjct: 193 AVGCIMAEVYT 203
Score = 48.0 bits (109), Expect = 3e-05
Identities = 24/64 (37%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M RY + +LG+G+YG V R+ ++GE++A+KK ++ + + LRE++ LK L H
Sbjct: 9 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKK-MKRKFYSWEECMNLREVKSLKKLNH 67
Query: 235 PNLV 246
N+V
Sbjct: 68 ANVV 71
>AF390028-1|AAL58838.1| 993|Homo sapiens serine/threonine protein
kinase kkialre-like 1 protein.
Length = 993
Score = 133 bits (322), Expect = 5e-31
Identities = 58/76 (76%), Positives = 66/76 (86%), Gaps = 1/76 (1%)
Frame = +2
Query: 419 CIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYST 595
CIHRDVKPENIL+T V+KLCDFGFAR+++ P + YTDYVATRWYR+PELLVGDT Y
Sbjct: 794 CIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGP 853
Query: 596 PVDVWAIXCVFAELLT 643
PVDVWAI CVFAELL+
Sbjct: 854 PVDVWAIGCVFAELLS 869
Score = 103 bits (248), Expect = 4e-22
Identities = 44/56 (78%), Positives = 55/56 (98%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLK 222
ME+YEK+ K+GEGSYG+V+KCRNRDTG+IVA+KKF+E+EDDP+I+KIALREIRMLK
Sbjct: 191 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLK 246
Score = 67.7 bits (158), Expect = 3e-11
Identities = 28/35 (80%), Positives = 32/35 (91%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAG 346
L NL+EVFRRKR+LHLVFEYCDHTVLHEL++Y G
Sbjct: 668 LVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRG 702
>AF225919-1|AAF37278.1| 632|Homo sapiens intestinal cell kinase
protein.
Length = 632
Score = 130 bits (314), Expect = 4e-30
Identities = 59/131 (45%), Positives = 83/131 (63%)
Frame = +2
Query: 251 LIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
L EV R L+ +FEY + +++ PE + I++Q LQG+A+ H+ HR
Sbjct: 65 LKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKLGFFHR 124
Query: 431 DVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVW 610
D+KPEN+L +VK+ DFG AR I YTDYV+TRWYRAPE+L+ T YS+P+DVW
Sbjct: 125 DLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRWYRAPEVLLRSTNYSSPIDVW 184
Query: 611 AIXCVFAELLT 643
A+ C+ AE+ T
Sbjct: 185 AVGCIMAEVYT 195
Score = 45.6 bits (103), Expect = 2e-04
Identities = 23/64 (35%), Positives = 40/64 (62%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M RY + +LG+G+YG V R+ ++GE++A+KK ++ + + RE++ LK L H
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKK-MKRKFYSWEECMNQREVKSLKKLNH 59
Query: 235 PNLV 246
N+V
Sbjct: 60 ANVV 63
>BC039825-1|AAH39825.1| 457|Homo sapiens MAK protein protein.
Length = 457
Score = 129 bits (312), Expect = 7e-30
Identities = 57/132 (43%), Positives = 84/132 (63%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
+ L EV R L+ +FEY + ++ PE + + I++Q LQG+A+ H+H
Sbjct: 62 VIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGF 121
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPV 601
HRD+KPEN+L +VK+ DFG AR + YTDYV+TRWYRAPE+L+ ++YS+P+
Sbjct: 122 FHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPI 181
Query: 602 DVWAIXCVFAEL 637
DVWA+ + AEL
Sbjct: 182 DVWAVGSIMAEL 193
Score = 47.2 bits (107), Expect = 5e-05
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M RY + +LG+G+YG V ++ ++GE+VA+K+ ++ + + LRE++ LK L H
Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKR-MKRKFYSWDECMNLREVKSLKKLNH 59
Query: 235 PNLV 246
N++
Sbjct: 60 ANVI 63
>AL024498-4|CAB75823.1| 623|Homo sapiens protein ( ovel
serine/threonine-proteinila) (Deafglial cells missing
homolog 2 (Drosophila)).).
Length = 623
Score = 129 bits (312), Expect = 7e-30
Identities = 57/132 (43%), Positives = 84/132 (63%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
+ L EV R L+ +FEY + ++ PE + + I++Q LQG+A+ H+H
Sbjct: 62 VIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGF 121
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPV 601
HRD+KPEN+L +VK+ DFG AR + YTDYV+TRWYRAPE+L+ ++YS+P+
Sbjct: 122 FHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPI 181
Query: 602 DVWAIXCVFAEL 637
DVWA+ + AEL
Sbjct: 182 DVWAVGSIMAEL 193
Score = 47.2 bits (107), Expect = 5e-05
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M RY + +LG+G+YG V ++ ++GE+VA+K+ ++ + + LRE++ LK L H
Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKR-MKRKFYSWDECMNLREVKSLKKLNH 59
Query: 235 PNLV 246
N++
Sbjct: 60 ANVI 63
>AF505623-1|AAN16405.1| 623|Homo sapiens male germ cell-associated
kinase protein.
Length = 623
Score = 129 bits (312), Expect = 7e-30
Identities = 57/132 (43%), Positives = 84/132 (63%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
+ L EV R L+ +FEY + ++ PE + + I++Q LQG+A+ H+H
Sbjct: 62 VIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGF 121
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPV 601
HRD+KPEN+L +VK+ DFG AR + YTDYV+TRWYRAPE+L+ ++YS+P+
Sbjct: 122 FHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSPI 181
Query: 602 DVWAIXCVFAEL 637
DVWA+ + AEL
Sbjct: 182 DVWAVGSIMAEL 193
Score = 47.2 bits (107), Expect = 5e-05
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M RY + +LG+G+YG V ++ ++GE+VA+K+ ++ + + LRE++ LK L H
Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKR-MKRKFYSWDECMNLREVKSLKKLNH 59
Query: 235 PNLV 246
N++
Sbjct: 60 ANVI 63
>X66365-1|CAA47008.1| 326|Homo sapiens serine/threonine protein
kinase protein.
Length = 326
Score = 126 bits (304), Expect = 7e-29
Identities = 62/135 (45%), Positives = 90/135 (66%), Gaps = 3/135 (2%)
Frame = +2
Query: 242 LFNLIEVFR--RKRKLHLVFEYCDHTVLHELEKYPA-GCPELLSKQIIWQTLQGVAYCHR 412
LF++ V R R+ KL LVFE+ D + L+K P G P K +++Q L+G+ + H
Sbjct: 79 LFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHS 138
Query: 413 HNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYS 592
H +HRD+KP+NIL+TS G +KL DFG AR+ S + T V T WYRAPE+L+ + Y+
Sbjct: 139 HRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLL-QSSYA 197
Query: 593 TPVDVWAIXCVFAEL 637
TPVD+W++ C+FAE+
Sbjct: 198 TPVDLWSVGCIFAEM 212
Score = 45.2 bits (102), Expect = 2e-04
Identities = 27/69 (39%), Positives = 46/69 (66%), Gaps = 6/69 (8%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRN-RDTGEIVAVKKF---VENEDDPL--IRKIALREIRML 219
++YE +A++GEG+YG V+K R+ ++ G VA+K+ E PL IR++A+ +R L
Sbjct: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAV--LRHL 68
Query: 220 KNLKHPNLV 246
+ +HPN+V
Sbjct: 69 ETFEHPNVV 77
>BC052264-1|AAH52264.1| 326|Homo sapiens cyclin-dependent kinase 6
protein.
Length = 326
Score = 126 bits (304), Expect = 7e-29
Identities = 62/135 (45%), Positives = 90/135 (66%), Gaps = 3/135 (2%)
Frame = +2
Query: 242 LFNLIEVFR--RKRKLHLVFEYCDHTVLHELEKYPA-GCPELLSKQIIWQTLQGVAYCHR 412
LF++ V R R+ KL LVFE+ D + L+K P G P K +++Q L+G+ + H
Sbjct: 79 LFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHS 138
Query: 413 HNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYS 592
H +HRD+KP+NIL+TS G +KL DFG AR+ S + T V T WYRAPE+L+ + Y+
Sbjct: 139 HRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLL-QSSYA 197
Query: 593 TPVDVWAIXCVFAEL 637
TPVD+W++ C+FAE+
Sbjct: 198 TPVDLWSVGCIFAEM 212
Score = 45.2 bits (102), Expect = 2e-04
Identities = 27/69 (39%), Positives = 46/69 (66%), Gaps = 6/69 (8%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRN-RDTGEIVAVKKF---VENEDDPL--IRKIALREIRML 219
++YE +A++GEG+YG V+K R+ ++ G VA+K+ E PL IR++A+ +R L
Sbjct: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAV--LRHL 68
Query: 220 KNLKHPNLV 246
+ +HPN+V
Sbjct: 69 ETFEHPNVV 77
>AY128534-1|AAM76970.1| 326|Homo sapiens cyclin-dependent kinase 6
protein.
Length = 326
Score = 126 bits (304), Expect = 7e-29
Identities = 62/135 (45%), Positives = 90/135 (66%), Gaps = 3/135 (2%)
Frame = +2
Query: 242 LFNLIEVFR--RKRKLHLVFEYCDHTVLHELEKYPA-GCPELLSKQIIWQTLQGVAYCHR 412
LF++ V R R+ KL LVFE+ D + L+K P G P K +++Q L+G+ + H
Sbjct: 79 LFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHS 138
Query: 413 HNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYS 592
H +HRD+KP+NIL+TS G +KL DFG AR+ S + T V T WYRAPE+L+ + Y+
Sbjct: 139 HRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLL-QSSYA 197
Query: 593 TPVDVWAIXCVFAEL 637
TPVD+W++ C+FAE+
Sbjct: 198 TPVDLWSVGCIFAEM 212
Score = 45.2 bits (102), Expect = 2e-04
Identities = 27/69 (39%), Positives = 46/69 (66%), Gaps = 6/69 (8%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRN-RDTGEIVAVKKF---VENEDDPL--IRKIALREIRML 219
++YE +A++GEG+YG V+K R+ ++ G VA+K+ E PL IR++A+ +R L
Sbjct: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAV--LRHL 68
Query: 220 KNLKHPNLV 246
+ +HPN+V
Sbjct: 69 ETFEHPNVV 77
>Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycle
control gene CDC2. ).
Length = 297
Score = 124 bits (300), Expect = 2e-28
Identities = 57/139 (41%), Positives = 84/139 (60%), Gaps = 3/139 (2%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAG--CPELLSKQIIWQTLQGVAYCHRH 415
+ +L +V + +L+L+FE+ + L+ P G L K ++Q LQG+ +CH
Sbjct: 63 IVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSR 122
Query: 416 NCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYS 592
+HRD+KP+N+L+ G +KL DFG AR P YT V T WYR+PE+L+G YS
Sbjct: 123 RVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYS 182
Query: 593 TPVDVWAIXCVFAELLTSE 649
TPVD+W+I +FAEL T +
Sbjct: 183 TPVDIWSIGTIFAELATKK 201
Score = 72.5 bits (170), Expect = 1e-12
Identities = 31/64 (48%), Positives = 47/64 (73%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME Y K+ K+GEG+YG+VYK R++ TG++VA+KK ++ + A+REI +LK L+H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 235 PNLV 246
PN+V
Sbjct: 61 PNIV 64
>X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene
involved in cell cycle control. ).
Length = 297
Score = 124 bits (300), Expect = 2e-28
Identities = 57/139 (41%), Positives = 84/139 (60%), Gaps = 3/139 (2%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAG--CPELLSKQIIWQTLQGVAYCHRH 415
+ +L +V + +L+L+FE+ + L+ P G L K ++Q LQG+ +CH
Sbjct: 63 IVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSR 122
Query: 416 NCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYS 592
+HRD+KP+N+L+ G +KL DFG AR P YT V T WYR+PE+L+G YS
Sbjct: 123 RVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYS 182
Query: 593 TPVDVWAIXCVFAELLTSE 649
TPVD+W+I +FAEL T +
Sbjct: 183 TPVDIWSIGTIFAELATKK 201
Score = 72.5 bits (170), Expect = 1e-12
Identities = 31/64 (48%), Positives = 47/64 (73%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME Y K+ K+GEG+YG+VYK R++ TG++VA+KK ++ + A+REI +LK L+H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 235 PNLV 246
PN+V
Sbjct: 61 PNIV 64
>BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, G1
to S and G2 to M protein.
Length = 297
Score = 124 bits (300), Expect = 2e-28
Identities = 57/139 (41%), Positives = 84/139 (60%), Gaps = 3/139 (2%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAG--CPELLSKQIIWQTLQGVAYCHRH 415
+ +L +V + +L+L+FE+ + L+ P G L K ++Q LQG+ +CH
Sbjct: 63 IVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSR 122
Query: 416 NCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYS 592
+HRD+KP+N+L+ G +KL DFG AR P YT V T WYR+PE+L+G YS
Sbjct: 123 RVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYS 182
Query: 593 TPVDVWAIXCVFAELLTSE 649
TPVD+W+I +FAEL T +
Sbjct: 183 TPVDIWSIGTIFAELATKK 201
Score = 72.5 bits (170), Expect = 1e-12
Identities = 31/64 (48%), Positives = 47/64 (73%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME Y K+ K+GEG+YG+VYK R++ TG++VA+KK ++ + A+REI +LK L+H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 235 PNLV 246
PN+V
Sbjct: 61 PNIV 64
>BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein.
Length = 225
Score = 124 bits (300), Expect = 2e-28
Identities = 57/139 (41%), Positives = 84/139 (60%), Gaps = 3/139 (2%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAG--CPELLSKQIIWQTLQGVAYCHRH 415
+ +L +V + +L+L+FE+ + L+ P G L K ++Q LQG+ +CH
Sbjct: 63 IVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSR 122
Query: 416 NCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYS 592
+HRD+KP+N+L+ G +KL DFG AR P YT V T WYR+PE+L+G YS
Sbjct: 123 RVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYS 182
Query: 593 TPVDVWAIXCVFAELLTSE 649
TPVD+W+I +FAEL T +
Sbjct: 183 TPVDIWSIGTIFAELATKK 201
Score = 72.5 bits (170), Expect = 1e-12
Identities = 31/64 (48%), Positives = 47/64 (73%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME Y K+ K+GEG+YG+VYK R++ TG++VA+KK ++ + A+REI +LK L+H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 235 PNLV 246
PN+V
Sbjct: 61 PNIV 64
>BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, G1
to S and G2 to M protein.
Length = 297
Score = 124 bits (300), Expect = 2e-28
Identities = 57/139 (41%), Positives = 84/139 (60%), Gaps = 3/139 (2%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAG--CPELLSKQIIWQTLQGVAYCHRH 415
+ +L +V + +L+L+FE+ + L+ P G L K ++Q LQG+ +CH
Sbjct: 63 IVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSR 122
Query: 416 NCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYS 592
+HRD+KP+N+L+ G +KL DFG AR P YT V T WYR+PE+L+G YS
Sbjct: 123 RVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYS 182
Query: 593 TPVDVWAIXCVFAELLTSE 649
TPVD+W+I +FAEL T +
Sbjct: 183 TPVDIWSIGTIFAELATKK 201
Score = 72.5 bits (170), Expect = 1e-12
Identities = 31/64 (48%), Positives = 47/64 (73%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME Y K+ K+GEG+YG+VYK R++ TG++VA+KK ++ + A+REI +LK L+H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 235 PNLV 246
PN+V
Sbjct: 61 PNIV 64
>AF512554-1|AAM34793.1| 297|Homo sapiens cell division cycle 2, G1
to S and G2 to M protein.
Length = 297
Score = 124 bits (300), Expect = 2e-28
Identities = 57/139 (41%), Positives = 84/139 (60%), Gaps = 3/139 (2%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAG--CPELLSKQIIWQTLQGVAYCHRH 415
+ +L +V + +L+L+FE+ + L+ P G L K ++Q LQG+ +CH
Sbjct: 63 IVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSR 122
Query: 416 NCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYS 592
+HRD+KP+N+L+ G +KL DFG AR P YT V T WYR+PE+L+G YS
Sbjct: 123 RVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYS 182
Query: 593 TPVDVWAIXCVFAELLTSE 649
TPVD+W+I +FAEL T +
Sbjct: 183 TPVDIWSIGTIFAELATKK 201
Score = 72.5 bits (170), Expect = 1e-12
Identities = 31/64 (48%), Positives = 47/64 (73%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME Y K+ K+GEG+YG+VYK R++ TG++VA+KK ++ + A+REI +LK L+H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 235 PNLV 246
PN+V
Sbjct: 61 PNIV 64
>X66363-1|CAA47006.1| 496|Homo sapiens serine/threonine protein
kinase protein.
Length = 496
Score = 121 bits (292), Expect = 2e-27
Identities = 56/139 (40%), Positives = 89/139 (64%), Gaps = 5/139 (3%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLS----KQIIWQTLQGVAYCH 409
+ L ++ ++ L LVFEY D +L++Y C +++ K ++Q L+G+AYCH
Sbjct: 223 IVTLHDIIHTEKSLTLVFEYLDK----DLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCH 278
Query: 410 RHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTM 586
R +HRD+KP+N+L+ G +KL DFG AR S P ++Y++ V T WYR P++L+G T
Sbjct: 279 RQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTD 338
Query: 587 YSTPVDVWAIXCVFAELLT 643
YST +D+W + C+F E+ T
Sbjct: 339 YSTQIDMWGVGCIFYEMAT 357
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/64 (43%), Positives = 43/64 (67%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E Y KL KLGEG+Y VYK +++ T +VA+K+ + E + A+RE+ +LK+LKH
Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKE-IRLEHEEGAPCTAIREVSLLKDLKH 220
Query: 235 PNLV 246
N+V
Sbjct: 221 ANIV 224
>BT006827-1|AAP35473.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 121 bits (292), Expect = 2e-27
Identities = 56/139 (40%), Positives = 89/139 (64%), Gaps = 5/139 (3%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLS----KQIIWQTLQGVAYCH 409
+ L ++ ++ L LVFEY D +L++Y C +++ K ++Q L+G+AYCH
Sbjct: 223 IVTLHDIIHTEKSLTLVFEYLDK----DLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCH 278
Query: 410 RHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTM 586
R +HRD+KP+N+L+ G +KL DFG AR S P ++Y++ V T WYR P++L+G T
Sbjct: 279 RQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTD 338
Query: 587 YSTPVDVWAIXCVFAELLT 643
YST +D+W + C+F E+ T
Sbjct: 339 YSTQIDMWGVGCIFYEMAT 357
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/64 (43%), Positives = 43/64 (67%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E Y KL KLGEG+Y VYK +++ T +VA+K+ + E + A+RE+ +LK+LKH
Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKE-IRLEHEEGAPCTAIREVSLLKDLKH 220
Query: 235 PNLV 246
N+V
Sbjct: 221 ANIV 224
>BC015607-1|AAH15607.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 121 bits (292), Expect = 2e-27
Identities = 56/139 (40%), Positives = 89/139 (64%), Gaps = 5/139 (3%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLS----KQIIWQTLQGVAYCH 409
+ L ++ ++ L LVFEY D +L++Y C +++ K ++Q L+G+AYCH
Sbjct: 223 IVTLHDIIHTEKSLTLVFEYLDK----DLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCH 278
Query: 410 RHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTM 586
R +HRD+KP+N+L+ G +KL DFG AR S P ++Y++ V T WYR P++L+G T
Sbjct: 279 RQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTD 338
Query: 587 YSTPVDVWAIXCVFAELLT 643
YST +D+W + C+F E+ T
Sbjct: 339 YSTQIDMWGVGCIFYEMAT 357
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/64 (43%), Positives = 43/64 (67%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E Y KL KLGEG+Y VYK +++ T +VA+K+ + E + A+RE+ +LK+LKH
Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKE-IRLEHEEGAPCTAIREVSLLKDLKH 220
Query: 235 PNLV 246
N+V
Sbjct: 221 ANIV 224
>BC009852-1|AAH09852.2| 395|Homo sapiens PCTK1 protein protein.
Length = 395
Score = 121 bits (292), Expect = 2e-27
Identities = 56/139 (40%), Positives = 89/139 (64%), Gaps = 5/139 (3%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLS----KQIIWQTLQGVAYCH 409
+ L ++ ++ L LVFEY D +L++Y C +++ K ++Q L+G+AYCH
Sbjct: 122 IVTLHDIIHTEKSLTLVFEYLDK----DLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCH 177
Query: 410 RHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTM 586
R +HRD+KP+N+L+ G +KL DFG AR S P ++Y++ V T WYR P++L+G T
Sbjct: 178 RQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTD 237
Query: 587 YSTPVDVWAIXCVFAELLT 643
YST +D+W + C+F E+ T
Sbjct: 238 YSTQIDMWGVGCIFYEMAT 256
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/64 (43%), Positives = 43/64 (67%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E Y KL KLGEG+Y VYK +++ T +VA+K+ + E + A+RE+ +LK+LKH
Sbjct: 61 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKE-IRLEHEEGAPCTAIREVSLLKDLKH 119
Query: 235 PNLV 246
N+V
Sbjct: 120 ANIV 123
>BC006190-1|AAH06190.1| 448|Homo sapiens PCTK1 protein protein.
Length = 448
Score = 121 bits (292), Expect = 2e-27
Identities = 56/139 (40%), Positives = 89/139 (64%), Gaps = 5/139 (3%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLS----KQIIWQTLQGVAYCH 409
+ L ++ ++ L LVFEY D +L++Y C +++ K ++Q L+G+AYCH
Sbjct: 175 IVTLHDIIHTEKSLTLVFEYLDK----DLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCH 230
Query: 410 RHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTM 586
R +HRD+KP+N+L+ G +KL DFG AR S P ++Y++ V T WYR P++L+G T
Sbjct: 231 RQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTD 290
Query: 587 YSTPVDVWAIXCVFAELLT 643
YST +D+W + C+F E+ T
Sbjct: 291 YSTQIDMWGVGCIFYEMAT 309
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/64 (43%), Positives = 43/64 (67%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E Y KL KLGEG+Y VYK +++ T +VA+K+ + E + A+RE+ +LK+LKH
Sbjct: 114 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKE-IRLEHEEGAPCTAIREVSLLKDLKH 172
Query: 235 PNLV 246
N+V
Sbjct: 173 ANIV 176
>BC001048-1|AAH01048.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 121 bits (292), Expect = 2e-27
Identities = 56/139 (40%), Positives = 89/139 (64%), Gaps = 5/139 (3%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLS----KQIIWQTLQGVAYCH 409
+ L ++ ++ L LVFEY D +L++Y C +++ K ++Q L+G+AYCH
Sbjct: 223 IVTLHDIIHTEKSLTLVFEYLDK----DLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCH 278
Query: 410 RHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTM 586
R +HRD+KP+N+L+ G +KL DFG AR S P ++Y++ V T WYR P++L+G T
Sbjct: 279 RQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTD 338
Query: 587 YSTPVDVWAIXCVFAELLT 643
YST +D+W + C+F E+ T
Sbjct: 339 YSTQIDMWGVGCIFYEMAT 357
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/64 (43%), Positives = 43/64 (67%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E Y KL KLGEG+Y VYK +++ T +VA+K+ + E + A+RE+ +LK+LKH
Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKE-IRLEHEEGAPCTAIREVSLLKDLKH 220
Query: 235 PNLV 246
N+V
Sbjct: 221 ANIV 224
>AL096791-1|CAD20055.1| 496|Homo sapiens PCTAIRE protein kinase 1
protein.
Length = 496
Score = 121 bits (292), Expect = 2e-27
Identities = 56/139 (40%), Positives = 89/139 (64%), Gaps = 5/139 (3%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLS----KQIIWQTLQGVAYCH 409
+ L ++ ++ L LVFEY D +L++Y C +++ K ++Q L+G+AYCH
Sbjct: 223 IVTLHDIIHTEKSLTLVFEYLDK----DLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCH 278
Query: 410 RHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTM 586
R +HRD+KP+N+L+ G +KL DFG AR S P ++Y++ V T WYR P++L+G T
Sbjct: 279 RQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTD 338
Query: 587 YSTPVDVWAIXCVFAELLT 643
YST +D+W + C+F E+ T
Sbjct: 339 YSTQIDMWGVGCIFYEMAT 357
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/64 (43%), Positives = 43/64 (67%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E Y KL KLGEG+Y VYK +++ T +VA+K+ + E + A+RE+ +LK+LKH
Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKE-IRLEHEEGAPCTAIREVSLLKDLKH 220
Query: 235 PNLV 246
N+V
Sbjct: 221 ANIV 224
>X66364-1|CAA47007.1| 292|Homo sapiens serine/threonine protein
kinase protein.
Length = 292
Score = 121 bits (291), Expect = 3e-27
Identities = 58/140 (41%), Positives = 87/140 (62%), Gaps = 6/140 (4%)
Frame = +2
Query: 236 RTLFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGC-----PELLSKQIIWQTLQGVA 400
+ + L +V +KL LVFE+CD +L+KY C PE++ K ++Q L+G+
Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEFCDQ----DLKKYFDSCNGDLDPEIV-KSFLFQLLKGLG 115
Query: 401 YCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVG 577
+CH N +HRD+KP+N+L+ +G +KL DFG AR P Y+ V T WYR P++L G
Sbjct: 116 FCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFG 175
Query: 578 DTMYSTPVDVWAIXCVFAEL 637
+YST +D+W+ C+FAEL
Sbjct: 176 AKLYSTSIDMWSAGCIFAEL 195
Score = 77.0 bits (181), Expect = 6e-14
Identities = 35/64 (54%), Positives = 49/64 (76%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M++YEKL K+GEG+YG V+K +NR+T EIVA+K+ ++DD + ALREI +LK LKH
Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 235 PNLV 246
N+V
Sbjct: 61 KNIV 64
>BT006680-1|AAP35326.1| 292|Homo sapiens cyclin-dependent kinase 5
protein.
Length = 292
Score = 121 bits (291), Expect = 3e-27
Identities = 58/140 (41%), Positives = 87/140 (62%), Gaps = 6/140 (4%)
Frame = +2
Query: 236 RTLFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGC-----PELLSKQIIWQTLQGVA 400
+ + L +V +KL LVFE+CD +L+KY C PE++ K ++Q L+G+
Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEFCDQ----DLKKYFDSCNGDLDPEIV-KSFLFQLLKGLG 115
Query: 401 YCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVG 577
+CH N +HRD+KP+N+L+ +G +KL DFG AR P Y+ V T WYR P++L G
Sbjct: 116 FCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFG 175
Query: 578 DTMYSTPVDVWAIXCVFAEL 637
+YST +D+W+ C+FAEL
Sbjct: 176 AKLYSTSIDMWSAGCIFAEL 195
Score = 77.0 bits (181), Expect = 6e-14
Identities = 35/64 (54%), Positives = 49/64 (76%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M++YEKL K+GEG+YG V+K +NR+T EIVA+K+ ++DD + ALREI +LK LKH
Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 235 PNLV 246
N+V
Sbjct: 61 KNIV 64
>BC005298-1|AAH05298.1| 346|Homo sapiens cyclin-dependent kinase 7
(MO15 homolog, Xenopus laevis, cdk-activating kinase)
protein.
Length = 346
Score = 121 bits (291), Expect = 3e-27
Identities = 58/134 (43%), Positives = 80/134 (59%), Gaps = 1/134 (0%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
+ L++ F K + LVF++ + + ++ K + TLQG+ Y HRH
Sbjct: 74 IIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHRHWI 133
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTP 598
+HRD+KP N+LL +GV+KL DFG A+ SP +YT V TRWYRAPELL G MY
Sbjct: 134 LHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVG 193
Query: 599 VDVWAIXCVFAELL 640
VD+WA+ C+ AELL
Sbjct: 194 VDMWAVGCILAELL 207
Score = 64.1 bits (149), Expect = 4e-10
Identities = 31/66 (46%), Positives = 45/66 (68%), Gaps = 3/66 (4%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFV---ENEDDPLIRKIALREIRMLKNL 228
+RYEKL LGEG + VYK R+++T +IVA+KK +E I + ALREI++L+ L
Sbjct: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 229 KHPNLV 246
HPN++
Sbjct: 70 SHPNII 75
>BC005115-1|AAH05115.1| 292|Homo sapiens cyclin-dependent kinase 5
protein.
Length = 292
Score = 121 bits (291), Expect = 3e-27
Identities = 58/140 (41%), Positives = 87/140 (62%), Gaps = 6/140 (4%)
Frame = +2
Query: 236 RTLFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGC-----PELLSKQIIWQTLQGVA 400
+ + L +V +KL LVFE+CD +L+KY C PE++ K ++Q L+G+
Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEFCDQ----DLKKYFDSCNGDLDPEIV-KSFLFQLLKGLG 115
Query: 401 YCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVG 577
+CH N +HRD+KP+N+L+ +G +KL DFG AR P Y+ V T WYR P++L G
Sbjct: 116 FCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFG 175
Query: 578 DTMYSTPVDVWAIXCVFAEL 637
+YST +D+W+ C+FAEL
Sbjct: 176 AKLYSTSIDMWSAGCIFAEL 195
Score = 77.0 bits (181), Expect = 6e-14
Identities = 35/64 (54%), Positives = 49/64 (76%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M++YEKL K+GEG+YG V+K +NR+T EIVA+K+ ++DD + ALREI +LK LKH
Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 235 PNLV 246
N+V
Sbjct: 61 KNIV 64
>AY049778-1|AAL15435.1| 292|Homo sapiens cyclin-dependent kinase 5
protein.
Length = 292
Score = 121 bits (291), Expect = 3e-27
Identities = 58/140 (41%), Positives = 87/140 (62%), Gaps = 6/140 (4%)
Frame = +2
Query: 236 RTLFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGC-----PELLSKQIIWQTLQGVA 400
+ + L +V +KL LVFE+CD +L+KY C PE++ K ++Q L+G+
Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEFCDQ----DLKKYFDSCNGDLDPEIV-KSFLFQLLKGLG 115
Query: 401 YCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVG 577
+CH N +HRD+KP+N+L+ +G +KL DFG AR P Y+ V T WYR P++L G
Sbjct: 116 FCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFG 175
Query: 578 DTMYSTPVDVWAIXCVFAEL 637
+YST +D+W+ C+FAEL
Sbjct: 176 AKLYSTSIDMWSAGCIFAEL 195
Score = 77.0 bits (181), Expect = 6e-14
Identities = 35/64 (54%), Positives = 49/64 (76%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M++YEKL K+GEG+YG V+K +NR+T EIVA+K+ ++DD + ALREI +LK LKH
Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 235 PNLV 246
N+V
Sbjct: 61 KNIV 64
>BT007299-1|AAP35963.1| 472|Homo sapiens PCTAIRE-motif protein
kinase 3 protein.
Length = 472
Score = 120 bits (289), Expect = 5e-27
Identities = 58/139 (41%), Positives = 87/139 (62%), Gaps = 5/139 (3%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLS----KQIIWQTLQGVAYCH 409
+ L ++ R L LVFEY D +L++Y C L+S K ++Q L+G+AYCH
Sbjct: 200 IVTLHDLIHTDRSLTLVFEYLDS----DLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCH 255
Query: 410 RHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTM 586
+HRD+KP+N+L+ G +KL DFG AR S P ++Y++ V T WYR P++L+G T
Sbjct: 256 HRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTE 315
Query: 587 YSTPVDVWAIXCVFAELLT 643
YSTP+D+W + C+ E+ T
Sbjct: 316 YSTPIDMWGVGCIHYEMAT 334
Score = 54.0 bits (124), Expect = 4e-07
Identities = 28/64 (43%), Positives = 42/64 (65%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E Y KL KLGEG+Y V+K R++ +VA+K+ + E + A+RE+ +LKNLKH
Sbjct: 139 LETYVKLDKLGEGTYATVFKGRSKLMENLVALKE-IRLEHEEGAPCTAIREVSLLKNLKH 197
Query: 235 PNLV 246
N+V
Sbjct: 198 ANIV 201
>BC011526-1|AAH11526.1| 472|Homo sapiens PCTAIRE protein kinase 3
protein.
Length = 472
Score = 120 bits (289), Expect = 5e-27
Identities = 58/139 (41%), Positives = 87/139 (62%), Gaps = 5/139 (3%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLS----KQIIWQTLQGVAYCH 409
+ L ++ R L LVFEY D +L++Y C L+S K ++Q L+G+AYCH
Sbjct: 200 IVTLHDLIHTDRSLTLVFEYLDS----DLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCH 255
Query: 410 RHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTM 586
+HRD+KP+N+L+ G +KL DFG AR S P ++Y++ V T WYR P++L+G T
Sbjct: 256 HRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTE 315
Query: 587 YSTPVDVWAIXCVFAELLT 643
YSTP+D+W + C+ E+ T
Sbjct: 316 YSTPIDMWGVGCIHYEMAT 334
Score = 54.0 bits (124), Expect = 4e-07
Identities = 28/64 (43%), Positives = 42/64 (65%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E Y KL KLGEG+Y V+K R++ +VA+K+ + E + A+RE+ +LKNLKH
Sbjct: 139 LETYVKLDKLGEGTYATVFKGRSKLMENLVALKE-IRLEHEEGAPCTAIREVSLLKNLKH 197
Query: 235 PNLV 246
N+V
Sbjct: 198 ANIV 201
>BC000281-1|AAH00281.2| 283|Homo sapiens PCTK3 protein protein.
Length = 283
Score = 120 bits (289), Expect = 5e-27
Identities = 58/139 (41%), Positives = 87/139 (62%), Gaps = 5/139 (3%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLS----KQIIWQTLQGVAYCH 409
+ L ++ R L LVFEY D +L++Y C L+S K ++Q L+G+AYCH
Sbjct: 11 IVTLHDLIHTDRSLTLVFEYLDS----DLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCH 66
Query: 410 RHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTM 586
+HRD+KP+N+L+ G +KL DFG AR S P ++Y++ V T WYR P++L+G T
Sbjct: 67 HRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTE 126
Query: 587 YSTPVDVWAIXCVFAELLT 643
YSTP+D+W + C+ E+ T
Sbjct: 127 YSTPIDMWGVGCIHYEMAT 145
>AY353238-1|AAR13066.1| 504|Homo sapiens PCTAIRE protein kinase 3
isoform b protein.
Length = 504
Score = 120 bits (289), Expect = 5e-27
Identities = 58/139 (41%), Positives = 87/139 (62%), Gaps = 5/139 (3%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLS----KQIIWQTLQGVAYCH 409
+ L ++ R L LVFEY D +L++Y C L+S K ++Q L+G+AYCH
Sbjct: 232 IVTLHDLIHTDRSLTLVFEYLDS----DLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCH 287
Query: 410 RHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTM 586
+HRD+KP+N+L+ G +KL DFG AR S P ++Y++ V T WYR P++L+G T
Sbjct: 288 HRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTE 347
Query: 587 YSTPVDVWAIXCVFAELLT 643
YSTP+D+W + C+ E+ T
Sbjct: 348 YSTPIDMWGVGCIHYEMAT 366
Score = 56.4 bits (130), Expect = 8e-08
Identities = 29/64 (45%), Positives = 43/64 (67%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E Y KL KLGEG+Y V+K R++ T +VA+K+ + E + A+RE+ +LKNLKH
Sbjct: 171 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKE-IRLEHEEGAPCTAIREVSLLKNLKH 229
Query: 235 PNLV 246
N+V
Sbjct: 230 ANIV 233
>AY353237-1|AAR13065.1| 474|Homo sapiens PCTAIRE protein kinase 3
isoform a protein.
Length = 474
Score = 120 bits (289), Expect = 5e-27
Identities = 58/139 (41%), Positives = 87/139 (62%), Gaps = 5/139 (3%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLS----KQIIWQTLQGVAYCH 409
+ L ++ R L LVFEY D +L++Y C L+S K ++Q L+G+AYCH
Sbjct: 202 IVTLHDLIHTDRSLTLVFEYLDS----DLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCH 257
Query: 410 RHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTM 586
+HRD+KP+N+L+ G +KL DFG AR S P ++Y++ V T WYR P++L+G T
Sbjct: 258 HRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTE 317
Query: 587 YSTPVDVWAIXCVFAELLT 643
YSTP+D+W + C+ E+ T
Sbjct: 318 YSTPIDMWGVGCIHYEMAT 336
Score = 56.4 bits (130), Expect = 8e-08
Identities = 29/64 (45%), Positives = 43/64 (67%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E Y KL KLGEG+Y V+K R++ T +VA+K+ + E + A+RE+ +LKNLKH
Sbjct: 141 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKE-IRLEHEEGAPCTAIREVSLLKNLKH 199
Query: 235 PNLV 246
N+V
Sbjct: 200 ANIV 203
>AL357131-4|CAH72012.1| 472|Homo sapiens PCTAIRE protein kinase 3
protein.
Length = 472
Score = 120 bits (289), Expect = 5e-27
Identities = 58/139 (41%), Positives = 87/139 (62%), Gaps = 5/139 (3%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLS----KQIIWQTLQGVAYCH 409
+ L ++ R L LVFEY D +L++Y C L+S K ++Q L+G+AYCH
Sbjct: 200 IVTLHDLIHTDRSLTLVFEYLDS----DLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCH 255
Query: 410 RHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTM 586
+HRD+KP+N+L+ G +KL DFG AR S P ++Y++ V T WYR P++L+G T
Sbjct: 256 HRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTE 315
Query: 587 YSTPVDVWAIXCVFAELLT 643
YSTP+D+W + C+ E+ T
Sbjct: 316 YSTPIDMWGVGCIHYEMAT 334
Score = 56.4 bits (130), Expect = 8e-08
Identities = 29/64 (45%), Positives = 43/64 (67%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E Y KL KLGEG+Y V+K R++ T +VA+K+ + E + A+RE+ +LKNLKH
Sbjct: 139 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKE-IRLEHEEGAPCTAIREVSLLKNLKH 197
Query: 235 PNLV 246
N+V
Sbjct: 198 ANIV 201
>AB209307-1|BAD92544.1| 436|Homo sapiens PCTAIRE protein kinase 3
isoform b variant protein.
Length = 436
Score = 120 bits (289), Expect = 5e-27
Identities = 58/139 (41%), Positives = 87/139 (62%), Gaps = 5/139 (3%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLS----KQIIWQTLQGVAYCH 409
+ L ++ R L LVFEY D +L++Y C L+S K ++Q L+G+AYCH
Sbjct: 164 IVTLHDLIHTDRSLTLVFEYLDS----DLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCH 219
Query: 410 RHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTM 586
+HRD+KP+N+L+ G +KL DFG AR S P ++Y++ V T WYR P++L+G T
Sbjct: 220 HRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTE 279
Query: 587 YSTPVDVWAIXCVFAELLT 643
YSTP+D+W + C+ E+ T
Sbjct: 280 YSTPIDMWGVGCIHYEMAT 298
Score = 56.4 bits (130), Expect = 8e-08
Identities = 29/64 (45%), Positives = 43/64 (67%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E Y KL KLGEG+Y V+K R++ T +VA+K+ + E + A+RE+ +LKNLKH
Sbjct: 103 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKE-IRLEHEEGAPCTAIREVSLLKNLKH 161
Query: 235 PNLV 246
N+V
Sbjct: 162 ANIV 165
>Z48970-1|CAA88834.1| 303|Homo sapiens orf protein.
Length = 303
Score = 119 bits (287), Expect = 8e-27
Identities = 59/124 (47%), Positives = 83/124 (66%), Gaps = 1/124 (0%)
Frame = +2
Query: 269 RKRKLHLVFEYCDHTVLHELEKYPA-GCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPE 445
R+ K+ LVFE+ D + L+K P G P K ++ Q L+G+ + H + +HRD+KPE
Sbjct: 85 REIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPE 144
Query: 446 NILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
NIL+TS G VKL DFG AR+ S + T V T WYRAPE+L+ T Y+TPVD+W++ C+
Sbjct: 145 NILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCI 203
Query: 626 FAEL 637
FAE+
Sbjct: 204 FAEM 207
Score = 41.1 bits (92), Expect = 0.003
Identities = 27/70 (38%), Positives = 42/70 (60%), Gaps = 8/70 (11%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKF-VENEDD-----PL--IRKIALREIRM 216
RYE +A++G G+YG VYK + +G VA+K V N P+ +R++AL +R
Sbjct: 5 RYEPVAEIGVGAYGTVYKACDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVAL--LRR 62
Query: 217 LKNLKHPNLV 246
L+ +HPN+V
Sbjct: 63 LEAFEHPNVV 72
>Y13120-1|CAA73587.1| 346|Homo sapiens serine/threonine protein
kinase protein.
Length = 346
Score = 119 bits (287), Expect = 8e-27
Identities = 57/134 (42%), Positives = 80/134 (59%), Gaps = 1/134 (0%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
+ L++ F K + LVF++ + + ++ K + TLQG+ Y H+H
Sbjct: 74 IIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWI 133
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTP 598
+HRD+KP N+LL +GV+KL DFG A+ SP +YT V TRWYRAPELL G MY
Sbjct: 134 LHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVG 193
Query: 599 VDVWAIXCVFAELL 640
VD+WA+ C+ AELL
Sbjct: 194 VDMWAVGCILAELL 207
Score = 64.1 bits (149), Expect = 4e-10
Identities = 31/66 (46%), Positives = 45/66 (68%), Gaps = 3/66 (4%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFV---ENEDDPLIRKIALREIRMLKNL 228
+RYEKL LGEG + VYK R+++T +IVA+KK +E I + ALREI++L+ L
Sbjct: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 229 KHPNLV 246
HPN++
Sbjct: 70 SHPNII 75
>X79193-1|CAA55785.1| 346|Homo sapiens MO15/CDK-activating kinase
(CAK) protein.
Length = 346
Score = 119 bits (287), Expect = 8e-27
Identities = 57/134 (42%), Positives = 80/134 (59%), Gaps = 1/134 (0%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
+ L++ F K + LVF++ + + ++ K + TLQG+ Y H+H
Sbjct: 74 IIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWI 133
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTP 598
+HRD+KP N+LL +GV+KL DFG A+ SP +YT V TRWYRAPELL G MY
Sbjct: 134 LHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVG 193
Query: 599 VDVWAIXCVFAELL 640
VD+WA+ C+ AELL
Sbjct: 194 VDMWAVGCILAELL 207
Score = 64.1 bits (149), Expect = 4e-10
Identities = 31/66 (46%), Positives = 45/66 (68%), Gaps = 3/66 (4%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFV---ENEDDPLIRKIALREIRMLKNL 228
+RYEKL LGEG + VYK R+++T +IVA+KK +E I + ALREI++L+ L
Sbjct: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 229 KHPNLV 246
HPN++
Sbjct: 70 SHPNII 75
>X77743-1|CAA54793.1| 346|Homo sapiens CDK activating kinase
protein.
Length = 346
Score = 119 bits (287), Expect = 8e-27
Identities = 57/134 (42%), Positives = 80/134 (59%), Gaps = 1/134 (0%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
+ L++ F K + LVF++ + + ++ K + TLQG+ Y H+H
Sbjct: 74 IIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWI 133
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTP 598
+HRD+KP N+LL +GV+KL DFG A+ SP +YT V TRWYRAPELL G MY
Sbjct: 134 LHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVG 193
Query: 599 VDVWAIXCVFAELL 640
VD+WA+ C+ AELL
Sbjct: 194 VDMWAVGCILAELL 207
Score = 64.1 bits (149), Expect = 4e-10
Identities = 31/66 (46%), Positives = 45/66 (68%), Gaps = 3/66 (4%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFV---ENEDDPLIRKIALREIRMLKNL 228
+RYEKL LGEG + VYK R+++T +IVA+KK +E I + ALREI++L+ L
Sbjct: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 229 KHPNLV 246
HPN++
Sbjct: 70 SHPNII 75
>X77303-1|CAA54508.1| 346|Homo sapiens Cdk-activating kinase
protein.
Length = 346
Score = 119 bits (287), Expect = 8e-27
Identities = 57/134 (42%), Positives = 80/134 (59%), Gaps = 1/134 (0%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
+ L++ F K + LVF++ + + ++ K + TLQG+ Y H+H
Sbjct: 74 IIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWI 133
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTP 598
+HRD+KP N+LL +GV+KL DFG A+ SP +YT V TRWYRAPELL G MY
Sbjct: 134 LHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVG 193
Query: 599 VDVWAIXCVFAELL 640
VD+WA+ C+ AELL
Sbjct: 194 VDMWAVGCILAELL 207
Score = 64.1 bits (149), Expect = 4e-10
Identities = 31/66 (46%), Positives = 45/66 (68%), Gaps = 3/66 (4%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFV---ENEDDPLIRKIALREIRMLKNL 228
+RYEKL LGEG + VYK R+++T +IVA+KK +E I + ALREI++L+ L
Sbjct: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 229 KHPNLV 246
HPN++
Sbjct: 70 SHPNII 75
>U81031-1|AAC39521.2| 303|Homo sapiens CDK4 protein.
Length = 303
Score = 119 bits (287), Expect = 8e-27
Identities = 59/124 (47%), Positives = 83/124 (66%), Gaps = 1/124 (0%)
Frame = +2
Query: 269 RKRKLHLVFEYCDHTVLHELEKYPA-GCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPE 445
R+ K+ LVFE+ D + L+K P G P K ++ Q L+G+ + H + +HRD+KPE
Sbjct: 85 REIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPE 144
Query: 446 NILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
NIL+TS G VKL DFG AR+ S + T V T WYRAPE+L+ T Y+TPVD+W++ C+
Sbjct: 145 NILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCI 203
Query: 626 FAEL 637
FAE+
Sbjct: 204 FAEM 207
Score = 44.4 bits (100), Expect = 4e-04
Identities = 28/70 (40%), Positives = 43/70 (61%), Gaps = 8/70 (11%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKF-VENEDD-----PL--IRKIALREIRM 216
RYE +A++G G+YG VYK R+ +G VA+K V N P+ +R++AL +R
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVAL--LRR 62
Query: 217 LKNLKHPNLV 246
L+ +HPN+V
Sbjct: 63 LEAFEHPNVV 72
>U79269-1|AAB50213.1| 229|Homo sapiens cyclin dependent protein
kinase protein.
Length = 229
Score = 119 bits (287), Expect = 8e-27
Identities = 59/124 (47%), Positives = 83/124 (66%), Gaps = 1/124 (0%)
Frame = +2
Query: 269 RKRKLHLVFEYCDHTVLHELEKYPA-GCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPE 445
R+ K+ LVFE+ D + L+K P G P K ++ Q L+G+ + H + +HRD+KPE
Sbjct: 11 REIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPE 70
Query: 446 NILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
NIL+TS G VKL DFG AR+ S + T V T WYRAPE+L+ T Y+TPVD+W++ C+
Sbjct: 71 NILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCI 129
Query: 626 FAEL 637
FAE+
Sbjct: 130 FAEM 133
>U37022-1|AAC50506.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 119 bits (287), Expect = 8e-27
Identities = 59/124 (47%), Positives = 83/124 (66%), Gaps = 1/124 (0%)
Frame = +2
Query: 269 RKRKLHLVFEYCDHTVLHELEKYPA-GCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPE 445
R+ K+ LVFE+ D + L+K P G P K ++ Q L+G+ + H + +HRD+KPE
Sbjct: 85 REIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPE 144
Query: 446 NILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
NIL+TS G VKL DFG AR+ S + T V T WYRAPE+L+ T Y+TPVD+W++ C+
Sbjct: 145 NILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCI 203
Query: 626 FAEL 637
FAE+
Sbjct: 204 FAEM 207
Score = 44.4 bits (100), Expect = 4e-04
Identities = 28/70 (40%), Positives = 43/70 (61%), Gaps = 8/70 (11%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKF-VENEDD-----PL--IRKIALREIRM 216
RYE +A++G G+YG VYK R+ +G VA+K V N P+ +R++AL +R
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVAL--LRR 62
Query: 217 LKNLKHPNLV 246
L+ +HPN+V
Sbjct: 63 LEAFEHPNVV 72
>M14505-1|AAA35673.1| 303|Homo sapiens cyclin-dependent protein
kinase, type 4 protein.
Length = 303
Score = 119 bits (287), Expect = 8e-27
Identities = 59/124 (47%), Positives = 83/124 (66%), Gaps = 1/124 (0%)
Frame = +2
Query: 269 RKRKLHLVFEYCDHTVLHELEKYPA-GCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPE 445
R+ K+ LVFE+ D + L+K P G P K ++ Q L+G+ + H + +HRD+KPE
Sbjct: 85 REIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPE 144
Query: 446 NILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
NIL+TS G VKL DFG AR+ S + T V T WYRAPE+L+ T Y+TPVD+W++ C+
Sbjct: 145 NILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCI 203
Query: 626 FAEL 637
FAE+
Sbjct: 204 FAEM 207
Score = 44.4 bits (100), Expect = 4e-04
Identities = 28/70 (40%), Positives = 43/70 (61%), Gaps = 8/70 (11%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKF-VENEDD-----PL--IRKIALREIRM 216
RYE +A++G G+YG VYK R+ +G VA+K V N P+ +R++AL +R
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVAL--LRR 62
Query: 217 LKNLKHPNLV 246
L+ +HPN+V
Sbjct: 63 LEAFEHPNVV 72
>L20320-1|AAA36657.1| 346|Homo sapiens protein serine/threonine
kinase protein.
Length = 346
Score = 119 bits (287), Expect = 8e-27
Identities = 57/134 (42%), Positives = 80/134 (59%), Gaps = 1/134 (0%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
+ L++ F K + LVF++ + + ++ K + TLQG+ Y H+H
Sbjct: 74 IIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWI 133
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTP 598
+HRD+KP N+LL +GV+KL DFG A+ SP +YT V TRWYRAPELL G MY
Sbjct: 134 LHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVG 193
Query: 599 VDVWAIXCVFAELL 640
VD+WA+ C+ AELL
Sbjct: 194 VDMWAVGCILAELL 207
Score = 64.1 bits (149), Expect = 4e-10
Identities = 31/66 (46%), Positives = 45/66 (68%), Gaps = 3/66 (4%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFV---ENEDDPLIRKIALREIRMLKNL 228
+RYEKL LGEG + VYK R+++T +IVA+KK +E I + ALREI++L+ L
Sbjct: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 229 KHPNLV 246
HPN++
Sbjct: 70 SHPNII 75
>CR542247-1|CAG47043.1| 303|Homo sapiens CDK4 protein.
Length = 303
Score = 119 bits (287), Expect = 8e-27
Identities = 59/124 (47%), Positives = 83/124 (66%), Gaps = 1/124 (0%)
Frame = +2
Query: 269 RKRKLHLVFEYCDHTVLHELEKYPA-GCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPE 445
R+ K+ LVFE+ D + L+K P G P K ++ Q L+G+ + H + +HRD+KPE
Sbjct: 85 REIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPE 144
Query: 446 NILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
NIL+TS G VKL DFG AR+ S + T V T WYRAPE+L+ T Y+TPVD+W++ C+
Sbjct: 145 NILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCI 203
Query: 626 FAEL 637
FAE+
Sbjct: 204 FAEM 207
Score = 44.4 bits (100), Expect = 4e-04
Identities = 28/70 (40%), Positives = 43/70 (61%), Gaps = 8/70 (11%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKF-VENEDD-----PL--IRKIALREIRM 216
RYE +A++G G+YG VYK R+ +G VA+K V N P+ +R++AL +R
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVAL--LRR 62
Query: 217 LKNLKHPNLV 246
L+ +HPN+V
Sbjct: 63 LEAFEHPNVV 72
>CR407668-1|CAG28596.1| 303|Homo sapiens CDK4 protein.
Length = 303
Score = 119 bits (287), Expect = 8e-27
Identities = 59/124 (47%), Positives = 83/124 (66%), Gaps = 1/124 (0%)
Frame = +2
Query: 269 RKRKLHLVFEYCDHTVLHELEKYPA-GCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPE 445
R+ K+ LVFE+ D + L+K P G P K ++ Q L+G+ + H + +HRD+KPE
Sbjct: 85 REIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPE 144
Query: 446 NILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
NIL+TS G VKL DFG AR+ S + T V T WYRAPE+L+ T Y+TPVD+W++ C+
Sbjct: 145 NILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCI 203
Query: 626 FAEL 637
FAE+
Sbjct: 204 FAEM 207
Score = 44.4 bits (100), Expect = 4e-04
Identities = 28/70 (40%), Positives = 43/70 (61%), Gaps = 8/70 (11%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKF-VENEDD-----PL--IRKIALREIRM 216
RYE +A++G G+YG VYK R+ +G VA+K V N P+ +R++AL +R
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVAL--LRR 62
Query: 217 LKNLKHPNLV 246
L+ +HPN+V
Sbjct: 63 LEAFEHPNVV 72
>BC033005-1|AAH33005.1| 523|Homo sapiens PCTAIRE protein kinase 2
protein.
Length = 523
Score = 119 bits (287), Expect = 8e-27
Identities = 55/137 (40%), Positives = 87/137 (63%), Gaps = 5/137 (3%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLS----KQIIWQTLQGVAYCH 409
+ L ++ + L LVFEY D +L++Y C ++S K ++Q L+G+AYCH
Sbjct: 250 IVTLHDIVHTDKSLTLVFEYLDK----DLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCH 305
Query: 410 RHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTM 586
R +HRD+KP+N+L+ G +KL DFG AR S P ++Y++ V T WYR P++L+G +
Sbjct: 306 RRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSE 365
Query: 587 YSTPVDVWAIXCVFAEL 637
YST +D+W + C+F E+
Sbjct: 366 YSTQIDMWGVGCIFFEM 382
Score = 57.2 bits (132), Expect = 5e-08
Identities = 30/64 (46%), Positives = 43/64 (67%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME Y KL KLGEG+Y VYK R++ T +VA+K+ + E + A+RE+ +LK+LKH
Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKE-IRLEHEEGAPCTAIREVSLLKDLKH 247
Query: 235 PNLV 246
N+V
Sbjct: 248 ANIV 251
>BC010153-1|AAH10153.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 119 bits (287), Expect = 8e-27
Identities = 59/124 (47%), Positives = 83/124 (66%), Gaps = 1/124 (0%)
Frame = +2
Query: 269 RKRKLHLVFEYCDHTVLHELEKYPA-GCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPE 445
R+ K+ LVFE+ D + L+K P G P K ++ Q L+G+ + H + +HRD+KPE
Sbjct: 85 REIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPE 144
Query: 446 NILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
NIL+TS G VKL DFG AR+ S + T V T WYRAPE+L+ T Y+TPVD+W++ C+
Sbjct: 145 NILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCI 203
Query: 626 FAEL 637
FAE+
Sbjct: 204 FAEM 207
Score = 44.4 bits (100), Expect = 4e-04
Identities = 28/70 (40%), Positives = 43/70 (61%), Gaps = 8/70 (11%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKF-VENEDD-----PL--IRKIALREIRM 216
RYE +A++G G+YG VYK R+ +G VA+K V N P+ +R++AL +R
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVAL--LRR 62
Query: 217 LKNLKHPNLV 246
L+ +HPN+V
Sbjct: 63 LEAFEHPNVV 72
>BC005864-1|AAH05864.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 119 bits (287), Expect = 8e-27
Identities = 59/124 (47%), Positives = 83/124 (66%), Gaps = 1/124 (0%)
Frame = +2
Query: 269 RKRKLHLVFEYCDHTVLHELEKYPA-GCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPE 445
R+ K+ LVFE+ D + L+K P G P K ++ Q L+G+ + H + +HRD+KPE
Sbjct: 85 REIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPE 144
Query: 446 NILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
NIL+TS G VKL DFG AR+ S + T V T WYRAPE+L+ T Y+TPVD+W++ C+
Sbjct: 145 NILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCI 203
Query: 626 FAEL 637
FAE+
Sbjct: 204 FAEM 207
Score = 44.4 bits (100), Expect = 4e-04
Identities = 28/70 (40%), Positives = 43/70 (61%), Gaps = 8/70 (11%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKF-VENEDD-----PL--IRKIALREIRM 216
RYE +A++G G+YG VYK R+ +G VA+K V N P+ +R++AL +R
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVAL--LRR 62
Query: 217 LKNLKHPNLV 246
L+ +HPN+V
Sbjct: 63 LEAFEHPNVV 72
>BC003644-1|AAH03644.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 119 bits (287), Expect = 8e-27
Identities = 59/124 (47%), Positives = 83/124 (66%), Gaps = 1/124 (0%)
Frame = +2
Query: 269 RKRKLHLVFEYCDHTVLHELEKYPA-GCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPE 445
R+ K+ LVFE+ D + L+K P G P K ++ Q L+G+ + H + +HRD+KPE
Sbjct: 85 REIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPE 144
Query: 446 NILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
NIL+TS G VKL DFG AR+ S + T V T WYRAPE+L+ T Y+TPVD+W++ C+
Sbjct: 145 NILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCI 203
Query: 626 FAEL 637
FAE+
Sbjct: 204 FAEM 207
Score = 44.4 bits (100), Expect = 4e-04
Identities = 28/70 (40%), Positives = 43/70 (61%), Gaps = 8/70 (11%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKF-VENEDD-----PL--IRKIALREIRM 216
RYE +A++G G+YG VYK R+ +G VA+K V N P+ +R++AL +R
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVAL--LRR 62
Query: 217 LKNLKHPNLV 246
L+ +HPN+V
Sbjct: 63 LEAFEHPNVV 72
>BC000834-1|AAH00834.1| 346|Homo sapiens cyclin-dependent kinase 7
(MO15 homolog, Xenopus laevis, cdk-activating kinase)
protein.
Length = 346
Score = 119 bits (287), Expect = 8e-27
Identities = 57/134 (42%), Positives = 80/134 (59%), Gaps = 1/134 (0%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
+ L++ F K + LVF++ + + ++ K + TLQG+ Y H+H
Sbjct: 74 IIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWI 133
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTP 598
+HRD+KP N+LL +GV+KL DFG A+ SP +YT V TRWYRAPELL G MY
Sbjct: 134 LHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVG 193
Query: 599 VDVWAIXCVFAELL 640
VD+WA+ C+ AELL
Sbjct: 194 VDMWAVGCILAELL 207
Score = 64.1 bits (149), Expect = 4e-10
Identities = 31/66 (46%), Positives = 45/66 (68%), Gaps = 3/66 (4%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFV---ENEDDPLIRKIALREIRMLKNL 228
+RYEKL LGEG + VYK R+++T +IVA+KK +E I + ALREI++L+ L
Sbjct: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 229 KHPNLV 246
HPN++
Sbjct: 70 SHPNII 75
>AY130859-1|AAM77799.1| 346|Homo sapiens cyclin-dependent kinase 7
protein.
Length = 346
Score = 119 bits (287), Expect = 8e-27
Identities = 57/134 (42%), Positives = 80/134 (59%), Gaps = 1/134 (0%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNC 421
+ L++ F K + LVF++ + + ++ K + TLQG+ Y H+H
Sbjct: 74 IIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWI 133
Query: 422 IHRDVKPENILLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTP 598
+HRD+KP N+LL +GV+KL DFG A+ SP +YT V TRWYRAPELL G MY
Sbjct: 134 LHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVG 193
Query: 599 VDVWAIXCVFAELL 640
VD+WA+ C+ AELL
Sbjct: 194 VDMWAVGCILAELL 207
Score = 64.1 bits (149), Expect = 4e-10
Identities = 31/66 (46%), Positives = 45/66 (68%), Gaps = 3/66 (4%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFV---ENEDDPLIRKIALREIRMLKNL 228
+RYEKL LGEG + VYK R+++T +IVA+KK +E I + ALREI++L+ L
Sbjct: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 229 KHPNLV 246
HPN++
Sbjct: 70 SHPNII 75
>AF507942-1|AAM23014.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 119 bits (287), Expect = 8e-27
Identities = 59/124 (47%), Positives = 83/124 (66%), Gaps = 1/124 (0%)
Frame = +2
Query: 269 RKRKLHLVFEYCDHTVLHELEKYPA-GCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPE 445
R+ K+ LVFE+ D + L+K P G P K ++ Q L+G+ + H + +HRD+KPE
Sbjct: 85 REIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPE 144
Query: 446 NILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
NIL+TS G VKL DFG AR+ S + T V T WYRAPE+L+ T Y+TPVD+W++ C+
Sbjct: 145 NILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCI 203
Query: 626 FAEL 637
FAE+
Sbjct: 204 FAEM 207
Score = 44.4 bits (100), Expect = 4e-04
Identities = 28/70 (40%), Positives = 43/70 (61%), Gaps = 8/70 (11%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKF-VENEDD-----PL--IRKIALREIRM 216
RYE +A++G G+YG VYK R+ +G VA+K V N P+ +R++AL +R
Sbjct: 5 RYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVAL--LRR 62
Query: 217 LKNLKHPNLV 246
L+ +HPN+V
Sbjct: 63 LEAFEHPNVV 72
>CR457041-1|CAG33322.1| 292|Homo sapiens CDK5 protein.
Length = 292
Score = 119 bits (286), Expect = 1e-26
Identities = 58/140 (41%), Positives = 86/140 (61%), Gaps = 6/140 (4%)
Frame = +2
Query: 236 RTLFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGC-----PELLSKQIIWQTLQGVA 400
+ + L +V +KL LVFE+CD +L+KY C PE++ K ++Q L+G+
Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEFCDQ----DLKKYFDSCNGDLDPEIV-KSFLFQLLKGLG 115
Query: 401 YCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVG 577
+CH N +HRD+KP+N L+ +G +KL DFG AR P Y+ V T WYR P++L G
Sbjct: 116 FCHSRNVLHRDLKPQNPLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFG 175
Query: 578 DTMYSTPVDVWAIXCVFAEL 637
+YST +D+W+ C+FAEL
Sbjct: 176 AKLYSTSIDMWSAGCIFAEL 195
Score = 77.0 bits (181), Expect = 6e-14
Identities = 35/64 (54%), Positives = 49/64 (76%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
M++YEKL K+GEG+YG V+K +NR+T EIVA+K+ ++DD + ALREI +LK LKH
Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 235 PNLV 246
N+V
Sbjct: 61 KNIV 64
>AF119833-1|AAG43234.1| 469|Homo sapiens serine/threonine protein
kinase PFTAIRE-1 protein.
Length = 469
Score = 119 bits (286), Expect = 1e-26
Identities = 53/135 (39%), Positives = 84/135 (62%), Gaps = 1/135 (0%)
Frame = +2
Query: 251 LIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
L ++ K L LVFEY + ++K+P G K ++Q L+G++Y H+ +HR
Sbjct: 196 LHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHR 255
Query: 431 DVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYSTPVDV 607
D+KP+N+L++ G +KL DFG AR S P +Y++ V T WYR P++L+G T YST +D+
Sbjct: 256 DLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDM 315
Query: 608 WAIXCVFAELLTSEA 652
W + C+F E++ A
Sbjct: 316 WGVGCIFVEMIQGVA 330
Score = 54.8 bits (126), Expect = 3e-07
Identities = 30/65 (46%), Positives = 41/65 (63%), Gaps = 2/65 (3%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVK--KFVENEDDPLIRKIALREIRMLKNLK 231
+ YEKL KLGEGSY VYK +++ ++VA+K + E E P A+RE +LK LK
Sbjct: 133 DSYEKLEKLGEGSYATVYKGKSKVNWKLVALKVIRLQEEEGTPF---TAIREASLLKGLK 189
Query: 232 HPNLV 246
H N+V
Sbjct: 190 HANIV 194
>AC006036-1|AAF19245.1| 165|Homo sapiens unknown protein.
Length = 165
Score = 119 bits (286), Expect = 1e-26
Identities = 53/135 (39%), Positives = 84/135 (62%), Gaps = 1/135 (0%)
Frame = +2
Query: 251 LIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
L ++ K L LVFEY + ++K+P G K ++Q L+G++Y H+ +HR
Sbjct: 14 LHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHR 73
Query: 431 DVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYSTPVDV 607
D+KP+N+L++ G +KL DFG AR S P +Y++ V T WYR P++L+G T YST +D+
Sbjct: 74 DLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDM 133
Query: 608 WAIXCVFAELLTSEA 652
W + C+F E++ A
Sbjct: 134 WGVGCIFVEMIQGVA 148
>AB020641-1|BAA74857.2| 453|Homo sapiens KIAA0834 protein protein.
Length = 453
Score = 119 bits (286), Expect = 1e-26
Identities = 53/135 (39%), Positives = 84/135 (62%), Gaps = 1/135 (0%)
Frame = +2
Query: 251 LIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
L ++ K L LVFEY + ++K+P G K ++Q L+G++Y H+ +HR
Sbjct: 180 LHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHR 239
Query: 431 DVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYSTPVDV 607
D+KP+N+L++ G +KL DFG AR S P +Y++ V T WYR P++L+G T YST +D+
Sbjct: 240 DLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDM 299
Query: 608 WAIXCVFAELLTSEA 652
W + C+F E++ A
Sbjct: 300 WGVGCIFVEMIQGVA 314
Score = 58.0 bits (134), Expect = 3e-08
Identities = 31/65 (47%), Positives = 42/65 (64%), Gaps = 2/65 (3%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVK--KFVENEDDPLIRKIALREIRMLKNLK 231
+ YEKL KLGEGSY VYK +++ G++VA+K + E E P A+RE +LK LK
Sbjct: 117 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPF---TAIREASLLKGLK 173
Query: 232 HPNLV 246
H N+V
Sbjct: 174 HANIV 178
>BC150265-1|AAI50266.1| 1481|Homo sapiens CRKRS protein protein.
Length = 1481
Score = 118 bits (285), Expect = 1e-26
Identities = 56/128 (43%), Positives = 78/128 (60%), Gaps = 2/128 (1%)
Frame = +2
Query: 272 KRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K +LVFEY DH ++ LE E K + Q ++G+ YCH+ N +HRD+K NI
Sbjct: 806 KGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNI 865
Query: 452 LLTSDGVVKLCDFGFARMISPGES--YTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
LL + G +KL DFG AR+ + ES YT+ V T WYR PELL+G+ Y+ +DVW+ C+
Sbjct: 866 LLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCI 925
Query: 626 FAELLTSE 649
EL T +
Sbjct: 926 LGELFTKK 933
Score = 55.2 bits (127), Expect = 2e-07
Identities = 24/64 (37%), Positives = 45/64 (70%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+++++ + +GEG+YG VYK +++DTGE+VA+KK + + A+REI++L+ L H
Sbjct: 724 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH 783
Query: 235 PNLV 246
++V
Sbjct: 784 RSVV 787
>BC001274-1|AAH01274.1| 324|Homo sapiens CDC2L5 protein protein.
Length = 324
Score = 118 bits (285), Expect = 1e-26
Identities = 57/128 (44%), Positives = 78/128 (60%), Gaps = 2/128 (1%)
Frame = +2
Query: 272 KRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K +LVFEY DH ++ LE E K + Q ++G+ YCH+ N +HRD+K NI
Sbjct: 170 KGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNI 229
Query: 452 LLTSDGVVKLCDFGFARMISPGES--YTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
LL + G +KL DFG AR+ S ES YT+ V T WYR PELL+G+ Y+ +DVW+ C+
Sbjct: 230 LLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCI 289
Query: 626 FAELLTSE 649
EL T +
Sbjct: 290 LGELFTKK 297
Score = 57.2 bits (132), Expect = 5e-08
Identities = 24/64 (37%), Positives = 45/64 (70%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+++++ + +GEG+YG VYK R++DTGE+VA+KK + + A+REI++L+ L H
Sbjct: 88 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH 147
Query: 235 PNLV 246
+++
Sbjct: 148 QSII 151
>AY679523-1|AAT74623.1| 1512|Homo sapiens cell division cycle 2-like 5
(cholinesterase-related cell division controller)
protein.
Length = 1512
Score = 118 bits (285), Expect = 1e-26
Identities = 57/128 (44%), Positives = 78/128 (60%), Gaps = 2/128 (1%)
Frame = +2
Query: 272 KRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K +LVFEY DH ++ LE E K + Q ++G+ YCH+ N +HRD+K NI
Sbjct: 784 KGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNI 843
Query: 452 LLTSDGVVKLCDFGFARMISPGES--YTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
LL + G +KL DFG AR+ S ES YT+ V T WYR PELL+G+ Y+ +DVW+ C+
Sbjct: 844 LLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCI 903
Query: 626 FAELLTSE 649
EL T +
Sbjct: 904 LGELFTKK 911
Score = 57.2 bits (132), Expect = 5e-08
Identities = 24/64 (37%), Positives = 45/64 (70%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+++++ + +GEG+YG VYK R++DTGE+VA+KK + + A+REI++L+ L H
Sbjct: 702 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH 761
Query: 235 PNLV 246
+++
Sbjct: 762 QSII 765
>AJ297710-1|CAC10401.1| 1452|Homo sapiens CDC2L5 protein kinase
protein.
Length = 1452
Score = 118 bits (285), Expect = 1e-26
Identities = 57/128 (44%), Positives = 78/128 (60%), Gaps = 2/128 (1%)
Frame = +2
Query: 272 KRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K +LVFEY DH ++ LE E K + Q ++G+ YCH+ N +HRD+K NI
Sbjct: 784 KGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNI 843
Query: 452 LLTSDGVVKLCDFGFARMISPGES--YTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
LL + G +KL DFG AR+ S ES YT+ V T WYR PELL+G+ Y+ +DVW+ C+
Sbjct: 844 LLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCI 903
Query: 626 FAELLTSE 649
EL T +
Sbjct: 904 LGELFTKK 911
Score = 57.2 bits (132), Expect = 5e-08
Identities = 24/64 (37%), Positives = 45/64 (70%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+++++ + +GEG+YG VYK R++DTGE+VA+KK + + A+REI++L+ L H
Sbjct: 702 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH 761
Query: 235 PNLV 246
+++
Sbjct: 762 QSII 765
>AJ297709-1|CAC10400.1| 1512|Homo sapiens CDC2L5 protein kinase
protein.
Length = 1512
Score = 118 bits (285), Expect = 1e-26
Identities = 57/128 (44%), Positives = 78/128 (60%), Gaps = 2/128 (1%)
Frame = +2
Query: 272 KRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K +LVFEY DH ++ LE E K + Q ++G+ YCH+ N +HRD+K NI
Sbjct: 784 KGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNI 843
Query: 452 LLTSDGVVKLCDFGFARMISPGES--YTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
LL + G +KL DFG AR+ S ES YT+ V T WYR PELL+G+ Y+ +DVW+ C+
Sbjct: 844 LLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCI 903
Query: 626 FAELLTSE 649
EL T +
Sbjct: 904 LGELFTKK 911
Score = 57.2 bits (132), Expect = 5e-08
Identities = 24/64 (37%), Positives = 45/64 (70%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+++++ + +GEG+YG VYK R++DTGE+VA+KK + + A+REI++L+ L H
Sbjct: 702 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH 761
Query: 235 PNLV 246
+++
Sbjct: 762 QSII 765
>AF227198-1|AAF36401.1| 1490|Homo sapiens CrkRS protein.
Length = 1490
Score = 118 bits (285), Expect = 1e-26
Identities = 56/128 (43%), Positives = 78/128 (60%), Gaps = 2/128 (1%)
Frame = +2
Query: 272 KRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K +LVFEY DH ++ LE E K + Q ++G+ YCH+ N +HRD+K NI
Sbjct: 806 KGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNI 865
Query: 452 LLTSDGVVKLCDFGFARMISPGES--YTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
LL + G +KL DFG AR+ + ES YT+ V T WYR PELL+G+ Y+ +DVW+ C+
Sbjct: 866 LLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCI 925
Query: 626 FAELLTSE 649
EL T +
Sbjct: 926 LGELFTKK 933
Score = 56.4 bits (130), Expect = 8e-08
Identities = 25/64 (39%), Positives = 45/64 (70%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+++++ + +GEG+YG VYK R++DTGE+VA+KK + + A+REI++L+ L H
Sbjct: 724 VDKFDIIGIIGEGTYGQVYKARDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH 783
Query: 235 PNLV 246
++V
Sbjct: 784 RSVV 787
>AB020711-1|BAA74927.2| 1535|Homo sapiens KIAA0904 protein protein.
Length = 1535
Score = 118 bits (285), Expect = 1e-26
Identities = 56/128 (43%), Positives = 78/128 (60%), Gaps = 2/128 (1%)
Frame = +2
Query: 272 KRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K +LVFEY DH ++ LE E K + Q ++G+ YCH+ N +HRD+K NI
Sbjct: 860 KGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNI 919
Query: 452 LLTSDGVVKLCDFGFARMISPGES--YTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
LL + G +KL DFG AR+ + ES YT+ V T WYR PELL+G+ Y+ +DVW+ C+
Sbjct: 920 LLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCI 979
Query: 626 FAELLTSE 649
EL T +
Sbjct: 980 LGELFTKK 987
Score = 55.2 bits (127), Expect = 2e-07
Identities = 24/64 (37%), Positives = 45/64 (70%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+++++ + +GEG+YG VYK +++DTGE+VA+KK + + A+REI++L+ L H
Sbjct: 778 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH 837
Query: 235 PNLV 246
++V
Sbjct: 838 RSVV 841
>M80629-1|AAA58424.1| 418|Homo sapiens cdc2-related protein kinase
protein.
Length = 418
Score = 118 bits (284), Expect = 2e-26
Identities = 57/128 (44%), Positives = 78/128 (60%), Gaps = 2/128 (1%)
Frame = +2
Query: 272 KRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K +LVFEY DH ++ LE E K + Q ++G+ YCH+ N +HRD+K NI
Sbjct: 170 KGAFYLVFEYMDHDLMGLLESGLVHFYENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNI 229
Query: 452 LLTSDGVVKLCDFGFARMISPGES--YTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCV 625
LL + G +KL DFG AR+ S ES YT+ V T WYR PELL+G+ Y+ +DVW+ C+
Sbjct: 230 LLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCI 289
Query: 626 FAELLTSE 649
EL T +
Sbjct: 290 LGELFTKK 297
Score = 57.2 bits (132), Expect = 5e-08
Identities = 24/64 (37%), Positives = 45/64 (70%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+++++ + +GEG+YG VYK R++DTGE+VA+KK + + A+REI++L+ L H
Sbjct: 88 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH 147
Query: 235 PNLV 246
+++
Sbjct: 148 QSII 151
>AC006023-1|AAD54514.1| 727|Homo sapiens WUGSC:H_DJ1147A01.1
protein.
Length = 727
Score = 118 bits (283), Expect = 2e-26
Identities = 56/124 (45%), Positives = 77/124 (62%), Gaps = 2/124 (1%)
Frame = +2
Query: 284 HLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENILLTS 463
+LVFEY DH ++ LE E K + Q ++G+ YCH+ N +HRD+K NILL +
Sbjct: 3 YLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNN 62
Query: 464 DGVVKLCDFGFARMISPGES--YTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAEL 637
G +KL DFG AR+ S ES YT+ V T WYR PELL+G+ Y+ +DVW+ C+ EL
Sbjct: 63 RGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGEL 122
Query: 638 LTSE 649
T +
Sbjct: 123 FTKK 126
>X66360-1|CAA47004.1| 523|Homo sapiens serine/threonine protein
kinase protein.
Length = 523
Score = 117 bits (281), Expect = 4e-26
Identities = 54/137 (39%), Positives = 86/137 (62%), Gaps = 5/137 (3%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLS----KQIIWQTLQGVAYCH 409
+ L ++ + L LVFEY D +L++Y C ++S K ++Q L+G+AYCH
Sbjct: 250 IVTLHDIVHTDKSLTLVFEYLDK----DLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCH 305
Query: 410 RHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTM 586
R +HRD+KP+N+L+ G +KL DFG AR S P ++Y++ V T WYR P++L+G +
Sbjct: 306 RRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSE 365
Query: 587 YSTPVDVWAIXCVFAEL 637
Y T +D+W + C+F E+
Sbjct: 366 YLTQIDMWGVGCIFFEM 382
Score = 57.2 bits (132), Expect = 5e-08
Identities = 30/64 (46%), Positives = 43/64 (67%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
ME Y KL KLGEG+Y VYK R++ T +VA+K+ + E + A+RE+ +LK+LKH
Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKE-IRLEHEEGAPCTAIREVSLLKDLKH 247
Query: 235 PNLV 246
N+V
Sbjct: 248 ANIV 251
>X66362-1|CAA47005.1| 380|Homo sapiens serine/threonine protein
kinase protein.
Length = 380
Score = 116 bits (280), Expect = 6e-26
Identities = 57/139 (41%), Positives = 86/139 (61%), Gaps = 5/139 (3%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLS----KQIIWQTLQGVAYCH 409
+ L ++ R L LVFEY D +L++Y C L+S K ++Q L+G+AYCH
Sbjct: 108 IVTLHDLIHTDRSLTLVFEYLDS----DLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCH 163
Query: 410 RHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTM 586
+HRD+KP+N+L+ G +KL DFG AR S P ++Y++ V T WYR P++L+G T
Sbjct: 164 TRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTE 223
Query: 587 YSTPVDVWAIXCVFAELLT 643
YSTP+ +W + C+ E+ T
Sbjct: 224 YSTPIAMWGVGCIHYEMAT 242
Score = 56.4 bits (130), Expect = 8e-08
Identities = 29/64 (45%), Positives = 43/64 (67%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E Y KL KLGEG+Y V+K R++ T +VA+K+ + E + A+RE+ +LKNLKH
Sbjct: 47 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKE-IRLEHEEGAPCTAIREVSLLKNLKH 105
Query: 235 PNLV 246
N+V
Sbjct: 106 ANIV 109
>X78342-1|CAA55137.1| 360|Homo sapiens PISSLRE protein.
Length = 360
Score = 112 bits (270), Expect = 9e-25
Identities = 55/121 (45%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
Frame = +2
Query: 281 LHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENILLT 460
+ LV YC+ + LE P E K I+ Q L+G+ Y HR+ IHRD+K N+L+T
Sbjct: 113 IFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMT 172
Query: 461 SDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAEL 637
G VK DFG AR P + T V T WYRAPELL+G T +T +D+WA+ C+ AEL
Sbjct: 173 DKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAEL 232
Query: 638 L 640
L
Sbjct: 233 L 233
Score = 63.7 bits (148), Expect = 5e-10
Identities = 29/64 (45%), Positives = 46/64 (71%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
++ +EKL ++GEG+YG+VY+ R+ T EIVA+KK +++ I +LREI +L L+H
Sbjct: 36 VKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRH 95
Query: 235 PNLV 246
PN+V
Sbjct: 96 PNIV 99
>L33264-1|AAA60092.2| 314|Homo sapiens CDC2-related protein kinase
protein.
Length = 314
Score = 112 bits (270), Expect = 9e-25
Identities = 55/121 (45%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
Frame = +2
Query: 281 LHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENILLT 460
+ LV YC+ + LE P E K I+ Q L+G+ Y HR+ IHRD+K N+L+T
Sbjct: 84 IFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMT 143
Query: 461 SDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAEL 637
G VK DFG AR P + T V T WYRAPELL+G T +T +D+WA+ C+ AEL
Sbjct: 144 DKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAEL 203
Query: 638 L 640
L
Sbjct: 204 L 204
Score = 63.7 bits (148), Expect = 5e-10
Identities = 29/64 (45%), Positives = 46/64 (71%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
++ +EKL ++GEG+YG+VY+ R+ T EIVA+KK +++ I +LREI +L L+H
Sbjct: 7 VKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRH 66
Query: 235 PNLV 246
PN+V
Sbjct: 67 PNIV 70
>BC025301-1|AAH25301.1| 272|Homo sapiens CDK10 protein protein.
Length = 272
Score = 112 bits (270), Expect = 9e-25
Identities = 55/121 (45%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
Frame = +2
Query: 281 LHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENILLT 460
+ LV YC+ + LE P E K I+ Q L+G+ Y HR+ IHRD+K N+L+T
Sbjct: 42 IFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMT 101
Query: 461 SDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAEL 637
G VK DFG AR P + T V T WYRAPELL+G T +T +D+WA+ C+ AEL
Sbjct: 102 DKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAEL 161
Query: 638 L 640
L
Sbjct: 162 L 162
>BC017342-1|AAH17342.1| 283|Homo sapiens CDK10 protein protein.
Length = 283
Score = 112 bits (270), Expect = 9e-25
Identities = 55/121 (45%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
Frame = +2
Query: 281 LHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENILLT 460
+ LV YC+ + LE P E K I+ Q L+G+ Y HR+ IHRD+K N+L+T
Sbjct: 42 IFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMT 101
Query: 461 SDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAEL 637
G VK DFG AR P + T V T WYRAPELL+G T +T +D+WA+ C+ AEL
Sbjct: 102 DKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAEL 161
Query: 638 L 640
L
Sbjct: 162 L 162
>AJ010341-1|CAB37619.1| 360|Homo sapiens cyclin-dependent kinase
protein.
Length = 360
Score = 112 bits (270), Expect = 9e-25
Identities = 55/121 (45%), Positives = 72/121 (59%), Gaps = 1/121 (0%)
Frame = +2
Query: 281 LHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENILLT 460
+ LV YC+ + LE P E K I+ Q L+G+ Y HR+ IHRD+K N+L+T
Sbjct: 113 IFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMT 172
Query: 461 SDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAEL 637
G VK DFG AR P + T V T WYRAPELL+G T +T +D+WA+ C+ AEL
Sbjct: 173 DKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAEL 232
Query: 638 L 640
L
Sbjct: 233 L 233
Score = 63.7 bits (148), Expect = 5e-10
Identities = 29/64 (45%), Positives = 46/64 (71%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
++ +EKL ++GEG+YG+VY+ R+ T EIVA+KK +++ I +LREI +L L+H
Sbjct: 36 VKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRH 95
Query: 235 PNLV 246
PN+V
Sbjct: 96 PNIV 99
>Z84480-1|CAI20520.1| 502|Homo sapiens cell division cycle 2-like 6
(CDK8-like) protein.
Length = 502
Score = 111 bits (267), Expect = 2e-24
Identities = 60/141 (42%), Positives = 85/141 (60%), Gaps = 16/141 (11%)
Frame = +2
Query: 275 RKLHLVFEYCDHTVLHELE--------KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
RK+ L+F+Y +H + H ++ K P P + K +++Q L G+ Y H + +HR
Sbjct: 91 RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR 150
Query: 431 DVKPENILLTSDGV----VKLCDFGFARMI-SPGESYTDY---VATRWYRAPELLVGDTM 586
D+KP NIL+ +G VK+ D GFAR+ SP + D V T WYRAPELL+G
Sbjct: 151 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 210
Query: 587 YSTPVDVWAIXCVFAELLTSE 649
Y+ +D+WAI C+FAELLTSE
Sbjct: 211 YTKAIDIWAIGCIFAELLTSE 231
Score = 41.1 bits (92), Expect = 0.003
Identities = 24/57 (42%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Frame = +1
Query: 79 KLGEGSYGLVYKCRNRD-TGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNLV 246
K+G G+YG VYK R +D E K +E I A REI +L+ LKHPN++
Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALKQIEGTG---ISMSACREIALLRELKHPNVI 79
>BC037289-1|AAH37289.1| 502|Homo sapiens CDC2L6 protein protein.
Length = 502
Score = 111 bits (267), Expect = 2e-24
Identities = 60/141 (42%), Positives = 85/141 (60%), Gaps = 16/141 (11%)
Frame = +2
Query: 275 RKLHLVFEYCDHTVLHELE--------KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
RK+ L+F+Y +H + H ++ K P P + K +++Q L G+ Y H + +HR
Sbjct: 91 RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR 150
Query: 431 DVKPENILLTSDGV----VKLCDFGFARMI-SPGESYTDY---VATRWYRAPELLVGDTM 586
D+KP NIL+ +G VK+ D GFAR+ SP + D V T WYRAPELL+G
Sbjct: 151 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 210
Query: 587 YSTPVDVWAIXCVFAELLTSE 649
Y+ +D+WAI C+FAELLTSE
Sbjct: 211 YTKAIDIWAIGCIFAELLTSE 231
Score = 41.1 bits (92), Expect = 0.003
Identities = 24/57 (42%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Frame = +1
Query: 79 KLGEGSYGLVYKCRNRD-TGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNLV 246
K+G G+YG VYK R +D E K +E I A REI +L+ LKHPN++
Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALKQIEGTG---ISMSACREIALLRELKHPNVI 79
>BC024247-1|AAH24247.1| 502|Homo sapiens CDC2L6 protein protein.
Length = 502
Score = 111 bits (267), Expect = 2e-24
Identities = 60/141 (42%), Positives = 85/141 (60%), Gaps = 16/141 (11%)
Frame = +2
Query: 275 RKLHLVFEYCDHTVLHELE--------KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
RK+ L+F+Y +H + H ++ K P P + K +++Q L G+ Y H + +HR
Sbjct: 91 RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR 150
Query: 431 DVKPENILLTSDGV----VKLCDFGFARMI-SPGESYTDY---VATRWYRAPELLVGDTM 586
D+KP NIL+ +G VK+ D GFAR+ SP + D V T WYRAPELL+G
Sbjct: 151 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 210
Query: 587 YSTPVDVWAIXCVFAELLTSE 649
Y+ +D+WAI C+FAELLTSE
Sbjct: 211 YTKAIDIWAIGCIFAELLTSE 231
>AY028424-1|AAK27731.1| 502|Homo sapiens death-preventing kinase
protein.
Length = 502
Score = 111 bits (267), Expect = 2e-24
Identities = 60/141 (42%), Positives = 85/141 (60%), Gaps = 16/141 (11%)
Frame = +2
Query: 275 RKLHLVFEYCDHTVLHELE--------KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
RK+ L+F+Y +H + H ++ K P P + K +++Q L G+ Y H + +HR
Sbjct: 91 RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR 150
Query: 431 DVKPENILLTSDGV----VKLCDFGFARMI-SPGESYTDY---VATRWYRAPELLVGDTM 586
D+KP NIL+ +G VK+ D GFAR+ SP + D V T WYRAPELL+G
Sbjct: 151 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 210
Query: 587 YSTPVDVWAIXCVFAELLTSE 649
Y+ +D+WAI C+FAELLTSE
Sbjct: 211 YTKAIDIWAIGCIFAELLTSE 231
Score = 41.1 bits (92), Expect = 0.003
Identities = 24/57 (42%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Frame = +1
Query: 79 KLGEGSYGLVYKCRNRD-TGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNLV 246
K+G G+YG VYK R +D E K +E I A REI +L+ LKHPN++
Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALKQIEGTG---ISMSACREIALLRELKHPNVI 79
>AL603914-4|CAI41175.1| 502|Homo sapiens cell division cycle 2-like
6 (CDK8-like) protein.
Length = 502
Score = 111 bits (267), Expect = 2e-24
Identities = 60/141 (42%), Positives = 85/141 (60%), Gaps = 16/141 (11%)
Frame = +2
Query: 275 RKLHLVFEYCDHTVLHELE--------KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
RK+ L+F+Y +H + H ++ K P P + K +++Q L G+ Y H + +HR
Sbjct: 91 RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR 150
Query: 431 DVKPENILLTSDGV----VKLCDFGFARMI-SPGESYTDY---VATRWYRAPELLVGDTM 586
D+KP NIL+ +G VK+ D GFAR+ SP + D V T WYRAPELL+G
Sbjct: 151 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 210
Query: 587 YSTPVDVWAIXCVFAELLTSE 649
Y+ +D+WAI C+FAELLTSE
Sbjct: 211 YTKAIDIWAIGCIFAELLTSE 231
Score = 41.1 bits (92), Expect = 0.003
Identities = 24/57 (42%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Frame = +1
Query: 79 KLGEGSYGLVYKCRNRD-TGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNLV 246
K+G G+YG VYK R +D E K +E I A REI +L+ LKHPN++
Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALKQIEGTG---ISMSACREIALLRELKHPNVI 79
>AL603914-3|CAI41173.1| 251|Homo sapiens cell division cycle 2-like
6 (CDK8-like) protein.
Length = 251
Score = 111 bits (267), Expect = 2e-24
Identities = 60/141 (42%), Positives = 85/141 (60%), Gaps = 16/141 (11%)
Frame = +2
Query: 275 RKLHLVFEYCDHTVLHELE--------KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
RK+ L+F+Y +H + H ++ K P P + K +++Q L G+ Y H + +HR
Sbjct: 31 RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR 90
Query: 431 DVKPENILLTSDGV----VKLCDFGFARMI-SPGESYTDY---VATRWYRAPELLVGDTM 586
D+KP NIL+ +G VK+ D GFAR+ SP + D V T WYRAPELL+G
Sbjct: 91 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 150
Query: 587 YSTPVDVWAIXCVFAELLTSE 649
Y+ +D+WAI C+FAELLTSE
Sbjct: 151 YTKAIDIWAIGCIFAELLTSE 171
>AL603914-2|CAI41172.1| 442|Homo sapiens cell division cycle 2-like
6 (CDK8-like) protein.
Length = 442
Score = 111 bits (267), Expect = 2e-24
Identities = 60/141 (42%), Positives = 85/141 (60%), Gaps = 16/141 (11%)
Frame = +2
Query: 275 RKLHLVFEYCDHTVLHELE--------KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
RK+ L+F+Y +H + H ++ K P P + K +++Q L G+ Y H + +HR
Sbjct: 31 RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR 90
Query: 431 DVKPENILLTSDGV----VKLCDFGFARMI-SPGESYTDY---VATRWYRAPELLVGDTM 586
D+KP NIL+ +G VK+ D GFAR+ SP + D V T WYRAPELL+G
Sbjct: 91 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 150
Query: 587 YSTPVDVWAIXCVFAELLTSE 649
Y+ +D+WAI C+FAELLTSE
Sbjct: 151 YTKAIDIWAIGCIFAELLTSE 171
>AL512430-4|CAI40286.1| 502|Homo sapiens cell division cycle 2-like
6 (CDK8-like) protein.
Length = 502
Score = 111 bits (267), Expect = 2e-24
Identities = 60/141 (42%), Positives = 85/141 (60%), Gaps = 16/141 (11%)
Frame = +2
Query: 275 RKLHLVFEYCDHTVLHELE--------KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
RK+ L+F+Y +H + H ++ K P P + K +++Q L G+ Y H + +HR
Sbjct: 91 RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR 150
Query: 431 DVKPENILLTSDGV----VKLCDFGFARMI-SPGESYTDY---VATRWYRAPELLVGDTM 586
D+KP NIL+ +G VK+ D GFAR+ SP + D V T WYRAPELL+G
Sbjct: 151 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 210
Query: 587 YSTPVDVWAIXCVFAELLTSE 649
Y+ +D+WAI C+FAELLTSE
Sbjct: 211 YTKAIDIWAIGCIFAELLTSE 231
Score = 41.1 bits (92), Expect = 0.003
Identities = 24/57 (42%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Frame = +1
Query: 79 KLGEGSYGLVYKCRNRD-TGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNLV 246
K+G G+YG VYK R +D E K +E I A REI +L+ LKHPN++
Sbjct: 26 KVGRGTYGHVYKARRKDGKDEKEYALKQIEGTG---ISMSACREIALLRELKHPNVI 79
>AL512430-2|CAI40283.1| 251|Homo sapiens cell division cycle 2-like
6 (CDK8-like) protein.
Length = 251
Score = 111 bits (267), Expect = 2e-24
Identities = 60/141 (42%), Positives = 85/141 (60%), Gaps = 16/141 (11%)
Frame = +2
Query: 275 RKLHLVFEYCDHTVLHELE--------KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
RK+ L+F+Y +H + H ++ K P P + K +++Q L G+ Y H + +HR
Sbjct: 31 RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR 90
Query: 431 DVKPENILLTSDGV----VKLCDFGFARMI-SPGESYTDY---VATRWYRAPELLVGDTM 586
D+KP NIL+ +G VK+ D GFAR+ SP + D V T WYRAPELL+G
Sbjct: 91 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 150
Query: 587 YSTPVDVWAIXCVFAELLTSE 649
Y+ +D+WAI C+FAELLTSE
Sbjct: 151 YTKAIDIWAIGCIFAELLTSE 171
>AL512430-1|CAI40282.1| 442|Homo sapiens cell division cycle 2-like
6 (CDK8-like) protein.
Length = 442
Score = 111 bits (267), Expect = 2e-24
Identities = 60/141 (42%), Positives = 85/141 (60%), Gaps = 16/141 (11%)
Frame = +2
Query: 275 RKLHLVFEYCDHTVLHELE--------KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
RK+ L+F+Y +H + H ++ K P P + K +++Q L G+ Y H + +HR
Sbjct: 31 RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR 90
Query: 431 DVKPENILLTSDGV----VKLCDFGFARMI-SPGESYTDY---VATRWYRAPELLVGDTM 586
D+KP NIL+ +G VK+ D GFAR+ SP + D V T WYRAPELL+G
Sbjct: 91 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 150
Query: 587 YSTPVDVWAIXCVFAELLTSE 649
Y+ +D+WAI C+FAELLTSE
Sbjct: 151 YTKAIDIWAIGCIFAELLTSE 171
>AL353572-4|CAM17657.1| 346|Homo sapiens cell cycle related kinase
protein.
Length = 346
Score = 111 bits (267), Expect = 2e-24
Identities = 48/94 (51%), Positives = 65/94 (69%), Gaps = 2/94 (2%)
Frame = +2
Query: 365 KQIIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGES--YTDYV 538
K + L+GVA+CH +N +HRD+KP N+L+++ G +K+ DFG AR+ SP S YT V
Sbjct: 105 KSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQV 164
Query: 539 ATRWYRAPELLVGDTMYSTPVDVWAIXCVFAELL 640
ATRWYRAPELL G Y VD+W++ C+ ELL
Sbjct: 165 ATRWYRAPELLYGARQYDQGVDLWSVGCIMGELL 198
Score = 49.2 bits (112), Expect = 1e-05
Identities = 23/59 (38%), Positives = 40/59 (67%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLK 231
M++Y L ++GEG++G+V+K ++ +TGEIVA+KK + ALREI+ L+ ++
Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEME 59
>AF547664-1|AAN28684.1| 346|Homo sapiens cell cycle related kinase
protein.
Length = 346
Score = 111 bits (267), Expect = 2e-24
Identities = 48/94 (51%), Positives = 65/94 (69%), Gaps = 2/94 (2%)
Frame = +2
Query: 365 KQIIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGES--YTDYV 538
K + L+GVA+CH +N +HRD+KP N+L+++ G +K+ DFG AR+ SP S YT V
Sbjct: 105 KSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQV 164
Query: 539 ATRWYRAPELLVGDTMYSTPVDVWAIXCVFAELL 640
ATRWYRAPELL G Y VD+W++ C+ ELL
Sbjct: 165 ATRWYRAPELLYGARQYDQGVDLWSVGCIMGELL 198
Score = 49.2 bits (112), Expect = 1e-05
Identities = 23/59 (38%), Positives = 40/59 (67%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLK 231
M++Y L ++GEG++G+V+K ++ +TGEIVA+KK + ALREI+ L+ ++
Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEME 59
>AB028951-1|BAA82980.2| 501|Homo sapiens KIAA1028 protein protein.
Length = 501
Score = 111 bits (267), Expect = 2e-24
Identities = 60/141 (42%), Positives = 85/141 (60%), Gaps = 16/141 (11%)
Frame = +2
Query: 275 RKLHLVFEYCDHTVLHELE--------KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
RK+ L+F+Y +H + H ++ K P P + K +++Q L G+ Y H + +HR
Sbjct: 90 RKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHR 149
Query: 431 DVKPENILLTSDGV----VKLCDFGFARMI-SPGESYTDY---VATRWYRAPELLVGDTM 586
D+KP NIL+ +G VK+ D GFAR+ SP + D V T WYRAPELL+G
Sbjct: 150 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 209
Query: 587 YSTPVDVWAIXCVFAELLTSE 649
Y+ +D+WAI C+FAELLTSE
Sbjct: 210 YTKAIDIWAIGCIFAELLTSE 230
Score = 41.1 bits (92), Expect = 0.003
Identities = 24/57 (42%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Frame = +1
Query: 79 KLGEGSYGLVYKCRNRD-TGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNLV 246
K+G G+YG VYK R +D E K +E I A REI +L+ LKHPN++
Sbjct: 25 KVGRGTYGHVYKARRKDGKDEKEYALKQIEGTG---ISMSACREIALLRELKHPNVI 78
>X85753-1|CAA59754.1| 464|Homo sapiens CDK8 protein kinase protein.
Length = 464
Score = 111 bits (266), Expect = 3e-24
Identities = 60/141 (42%), Positives = 85/141 (60%), Gaps = 16/141 (11%)
Frame = +2
Query: 275 RKLHLVFEYCDHTVLHELE--------KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
RK+ L+F+Y +H + H ++ K P P + K +++Q L G+ Y H + +HR
Sbjct: 91 RKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHR 150
Query: 431 DVKPENILLTSDGV----VKLCDFGFARMI-SPGESYTDY---VATRWYRAPELLVGDTM 586
D+KP NIL+ +G VK+ D GFAR+ SP + D V T WYRAPELL+G
Sbjct: 151 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 210
Query: 587 YSTPVDVWAIXCVFAELLTSE 649
Y+ +D+WAI C+FAELLTSE
Sbjct: 211 YTKAIDIWAIGCIFAELLTSE 231
Score = 38.7 bits (86), Expect = 0.018
Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 79 KLGEGSYGLVYKCRNRD--TGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNLV 246
K+G G+YG VYK + +D + A+K+ +E I A REI +L+ LKHPN++
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQ-IEGTG---ISMSACREIALLRELKHPNVI 79
>BC107601-1|AAI07602.1| 463|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 463
Score = 111 bits (266), Expect = 3e-24
Identities = 60/141 (42%), Positives = 85/141 (60%), Gaps = 16/141 (11%)
Frame = +2
Query: 275 RKLHLVFEYCDHTVLHELE--------KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
RK+ L+F+Y +H + H ++ K P P + K +++Q L G+ Y H + +HR
Sbjct: 91 RKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHR 150
Query: 431 DVKPENILLTSDGV----VKLCDFGFARMI-SPGESYTDY---VATRWYRAPELLVGDTM 586
D+KP NIL+ +G VK+ D GFAR+ SP + D V T WYRAPELL+G
Sbjct: 151 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 210
Query: 587 YSTPVDVWAIXCVFAELLTSE 649
Y+ +D+WAI C+FAELLTSE
Sbjct: 211 YTKAIDIWAIGCIFAELLTSE 231
Score = 38.7 bits (86), Expect = 0.018
Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 79 KLGEGSYGLVYKCRNRD--TGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNLV 246
K+G G+YG VYK + +D + A+K+ +E I A REI +L+ LKHPN++
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQ-IEGTG---ISMSACREIALLRELKHPNVI 79
>BC105950-1|AAI05951.1| 463|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 463
Score = 111 bits (266), Expect = 3e-24
Identities = 60/141 (42%), Positives = 85/141 (60%), Gaps = 16/141 (11%)
Frame = +2
Query: 275 RKLHLVFEYCDHTVLHELE--------KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
RK+ L+F+Y +H + H ++ K P P + K +++Q L G+ Y H + +HR
Sbjct: 91 RKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHR 150
Query: 431 DVKPENILLTSDGV----VKLCDFGFARMI-SPGESYTDY---VATRWYRAPELLVGDTM 586
D+KP NIL+ +G VK+ D GFAR+ SP + D V T WYRAPELL+G
Sbjct: 151 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 210
Query: 587 YSTPVDVWAIXCVFAELLTSE 649
Y+ +D+WAI C+FAELLTSE
Sbjct: 211 YTKAIDIWAIGCIFAELLTSE 231
Score = 38.7 bits (86), Expect = 0.018
Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 79 KLGEGSYGLVYKCRNRD--TGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNLV 246
K+G G+YG VYK + +D + A+K+ +E I A REI +L+ LKHPN++
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQ-IEGTG---ISMSACREIALLRELKHPNVI 79
>BC104492-1|AAI04493.1| 464|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 464
Score = 111 bits (266), Expect = 3e-24
Identities = 60/141 (42%), Positives = 85/141 (60%), Gaps = 16/141 (11%)
Frame = +2
Query: 275 RKLHLVFEYCDHTVLHELE--------KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
RK+ L+F+Y +H + H ++ K P P + K +++Q L G+ Y H + +HR
Sbjct: 91 RKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHR 150
Query: 431 DVKPENILLTSDGV----VKLCDFGFARMI-SPGESYTDY---VATRWYRAPELLVGDTM 586
D+KP NIL+ +G VK+ D GFAR+ SP + D V T WYRAPELL+G
Sbjct: 151 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 210
Query: 587 YSTPVDVWAIXCVFAELLTSE 649
Y+ +D+WAI C+FAELLTSE
Sbjct: 211 YTKAIDIWAIGCIFAELLTSE 231
Score = 38.7 bits (86), Expect = 0.018
Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 79 KLGEGSYGLVYKCRNRD--TGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNLV 246
K+G G+YG VYK + +D + A+K+ +E I A REI +L+ LKHPN++
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQ-IEGTG---ISMSACREIALLRELKHPNVI 79
>BC069634-1|AAH69634.1| 463|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 463
Score = 111 bits (266), Expect = 3e-24
Identities = 60/141 (42%), Positives = 85/141 (60%), Gaps = 16/141 (11%)
Frame = +2
Query: 275 RKLHLVFEYCDHTVLHELE--------KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
RK+ L+F+Y +H + H ++ K P P + K +++Q L G+ Y H + +HR
Sbjct: 91 RKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHR 150
Query: 431 DVKPENILLTSDGV----VKLCDFGFARMI-SPGESYTDY---VATRWYRAPELLVGDTM 586
D+KP NIL+ +G VK+ D GFAR+ SP + D V T WYRAPELL+G
Sbjct: 151 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 210
Query: 587 YSTPVDVWAIXCVFAELLTSE 649
Y+ +D+WAI C+FAELLTSE
Sbjct: 211 YTKAIDIWAIGCIFAELLTSE 231
Score = 38.7 bits (86), Expect = 0.018
Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 79 KLGEGSYGLVYKCRNRD--TGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNLV 246
K+G G+YG VYK + +D + A+K+ +E I A REI +L+ LKHPN++
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQ-IEGTG---ISMSACREIALLRELKHPNVI 79
>AL590108-1|CAH72300.1| 464|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 464
Score = 111 bits (266), Expect = 3e-24
Identities = 60/141 (42%), Positives = 85/141 (60%), Gaps = 16/141 (11%)
Frame = +2
Query: 275 RKLHLVFEYCDHTVLHELE--------KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
RK+ L+F+Y +H + H ++ K P P + K +++Q L G+ Y H + +HR
Sbjct: 91 RKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHR 150
Query: 431 DVKPENILLTSDGV----VKLCDFGFARMI-SPGESYTDY---VATRWYRAPELLVGDTM 586
D+KP NIL+ +G VK+ D GFAR+ SP + D V T WYRAPELL+G
Sbjct: 151 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 210
Query: 587 YSTPVDVWAIXCVFAELLTSE 649
Y+ +D+WAI C+FAELLTSE
Sbjct: 211 YTKAIDIWAIGCIFAELLTSE 231
Score = 38.7 bits (86), Expect = 0.018
Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 79 KLGEGSYGLVYKCRNRD--TGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNLV 246
K+G G+YG VYK + +D + A+K+ +E I A REI +L+ LKHPN++
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQ-IEGTG---ISMSACREIALLRELKHPNVI 79
>AL159159-1|CAI16960.1| 464|Homo sapiens cyclin-dependent kinase 8
protein.
Length = 464
Score = 111 bits (266), Expect = 3e-24
Identities = 60/141 (42%), Positives = 85/141 (60%), Gaps = 16/141 (11%)
Frame = +2
Query: 275 RKLHLVFEYCDHTVLHELE--------KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
RK+ L+F+Y +H + H ++ K P P + K +++Q L G+ Y H + +HR
Sbjct: 91 RKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHR 150
Query: 431 DVKPENILLTSDGV----VKLCDFGFARMI-SPGESYTDY---VATRWYRAPELLVGDTM 586
D+KP NIL+ +G VK+ D GFAR+ SP + D V T WYRAPELL+G
Sbjct: 151 DLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARH 210
Query: 587 YSTPVDVWAIXCVFAELLTSE 649
Y+ +D+WAI C+FAELLTSE
Sbjct: 211 YTKAIDIWAIGCIFAELLTSE 231
Score = 38.7 bits (86), Expect = 0.018
Identities = 23/58 (39%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +1
Query: 79 KLGEGSYGLVYKCRNRD--TGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNLV 246
K+G G+YG VYK + +D + A+K+ +E I A REI +L+ LKHPN++
Sbjct: 26 KVGRGTYGHVYKAKRKDGKDDKDYALKQ-IEGTG---ISMSACREIALLRELKHPNVI 79
>X80230-1|CAA56516.1| 372|Homo sapiens serine/threonine protein
kinase protein.
Length = 372
Score = 110 bits (264), Expect = 5e-24
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 5/131 (3%)
Frame = +2
Query: 266 RRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPE 445
R K ++LVF++C+H + L K+++ L G+ Y HR+ +HRD+K
Sbjct: 94 RCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAA 153
Query: 446 NILLTSDGVVKLCDFGFARMISPGES-----YTDYVATRWYRAPELLVGDTMYSTPVDVW 610
N+L+T DGV+KL DFG AR S ++ YT+ V T WYR PELL+G+ Y P+D+W
Sbjct: 154 NVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLW 213
Query: 611 AIXCVFAELLT 643
C+ AE+ T
Sbjct: 214 GAGCIMAEMWT 224
Score = 64.1 bits (149), Expect = 4e-10
Identities = 30/64 (46%), Positives = 46/64 (71%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+ +YEKLAK+G+G++G V+K R+R TG+ VA+KK + + ALREI++L+ LKH
Sbjct: 16 VSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKH 75
Query: 235 PNLV 246
N+V
Sbjct: 76 ENVV 79
>L25676-1|AAA35668.1| 372|Homo sapiens CDC2-related kinase protein.
Length = 372
Score = 110 bits (264), Expect = 5e-24
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 5/131 (3%)
Frame = +2
Query: 266 RRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPE 445
R K ++LVF++C+H + L K+++ L G+ Y HR+ +HRD+K
Sbjct: 94 RCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAA 153
Query: 446 NILLTSDGVVKLCDFGFARMISPGES-----YTDYVATRWYRAPELLVGDTMYSTPVDVW 610
N+L+T DGV+KL DFG AR S ++ YT+ V T WYR PELL+G+ Y P+D+W
Sbjct: 154 NVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLW 213
Query: 611 AIXCVFAELLT 643
C+ AE+ T
Sbjct: 214 GAGCIMAEMWT 224
Score = 64.1 bits (149), Expect = 4e-10
Identities = 30/64 (46%), Positives = 46/64 (71%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+ +YEKLAK+G+G++G V+K R+R TG+ VA+KK + + ALREI++L+ LKH
Sbjct: 16 VSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKH 75
Query: 235 PNLV 246
N+V
Sbjct: 76 ENVV 79
>BC038807-1|AAH38807.1| 349|Homo sapiens ALS2CR7 protein protein.
Length = 349
Score = 110 bits (264), Expect = 5e-24
Identities = 49/134 (36%), Positives = 79/134 (58%), Gaps = 1/134 (0%)
Frame = +2
Query: 251 LIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
L ++ K L VFEY + + ++P G + ++Q L+G+AY H + +HR
Sbjct: 113 LHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHR 172
Query: 431 DVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYSTPVDV 607
D+KP+N+L++ G +KL DFG AR S P ++Y+ V T WYR P+ L+G T YS+ +D+
Sbjct: 173 DLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDI 232
Query: 608 WAIXCVFAELLTSE 649
W C+F E+ +
Sbjct: 233 WGAGCIFIEMFQGQ 246
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/61 (45%), Positives = 38/61 (62%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y L KLGEGSY VYK +R G++VA+K N ++ + A+RE +LK LKH N+
Sbjct: 52 YLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG-VPFTAIREASLLKGLKHANI 110
Query: 244 V 246
V
Sbjct: 111 V 111
>BC001968-1|AAH01968.1| 372|Homo sapiens cyclin-dependent kinase 9
(CDC2-related kinase) protein.
Length = 372
Score = 110 bits (264), Expect = 5e-24
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 5/131 (3%)
Frame = +2
Query: 266 RRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPE 445
R K ++LVF++C+H + L K+++ L G+ Y HR+ +HRD+K
Sbjct: 94 RCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAA 153
Query: 446 NILLTSDGVVKLCDFGFARMISPGES-----YTDYVATRWYRAPELLVGDTMYSTPVDVW 610
N+L+T DGV+KL DFG AR S ++ YT+ V T WYR PELL+G+ Y P+D+W
Sbjct: 154 NVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLW 213
Query: 611 AIXCVFAELLT 643
C+ AE+ T
Sbjct: 214 GAGCIMAEMWT 224
Score = 64.1 bits (149), Expect = 4e-10
Identities = 30/64 (46%), Positives = 46/64 (71%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+ +YEKLAK+G+G++G V+K R+R TG+ VA+KK + + ALREI++L+ LKH
Sbjct: 16 VSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKH 75
Query: 235 PNLV 246
N+V
Sbjct: 76 ENVV 79
>AL162586-9|CAI39768.1| 372|Homo sapiens cyclin-dependent kinase 9
(CDC2-related kinase) protein.
Length = 372
Score = 110 bits (264), Expect = 5e-24
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 5/131 (3%)
Frame = +2
Query: 266 RRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPE 445
R K ++LVF++C+H + L K+++ L G+ Y HR+ +HRD+K
Sbjct: 94 RCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAA 153
Query: 446 NILLTSDGVVKLCDFGFARMISPGES-----YTDYVATRWYRAPELLVGDTMYSTPVDVW 610
N+L+T DGV+KL DFG AR S ++ YT+ V T WYR PELL+G+ Y P+D+W
Sbjct: 154 NVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLW 213
Query: 611 AIXCVFAELLT 643
C+ AE+ T
Sbjct: 214 GAGCIMAEMWT 224
Score = 64.1 bits (149), Expect = 4e-10
Identities = 30/64 (46%), Positives = 46/64 (71%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+ +YEKLAK+G+G++G V+K R+R TG+ VA+KK + + ALREI++L+ LKH
Sbjct: 16 VSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKH 75
Query: 235 PNLV 246
N+V
Sbjct: 76 ENVV 79
>AF517840-1|AAM54039.1| 372|Homo sapiens cyclin-dependent kinase 9
(CDC2-related kinase) protein.
Length = 372
Score = 110 bits (264), Expect = 5e-24
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 5/131 (3%)
Frame = +2
Query: 266 RRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPE 445
R K ++LVF++C+H + L K+++ L G+ Y HR+ +HRD+K
Sbjct: 94 RCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAA 153
Query: 446 NILLTSDGVVKLCDFGFARMISPGES-----YTDYVATRWYRAPELLVGDTMYSTPVDVW 610
N+L+T DGV+KL DFG AR S ++ YT+ V T WYR PELL+G+ Y P+D+W
Sbjct: 154 NVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLW 213
Query: 611 AIXCVFAELLT 643
C+ AE+ T
Sbjct: 214 GAGCIMAEMWT 224
Score = 64.1 bits (149), Expect = 4e-10
Identities = 30/64 (46%), Positives = 46/64 (71%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+ +YEKLAK+G+G++G V+K R+R TG+ VA+KK + + ALREI++L+ LKH
Sbjct: 16 VSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKH 75
Query: 235 PNLV 246
N+V
Sbjct: 76 ENVV 79
>AF255306-1|AAF72183.1| 372|Homo sapiens protein kinase CDK9
protein.
Length = 372
Score = 110 bits (264), Expect = 5e-24
Identities = 52/131 (39%), Positives = 77/131 (58%), Gaps = 5/131 (3%)
Frame = +2
Query: 266 RRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPE 445
R K ++LVF++C+H + L K+++ L G+ Y HR+ +HRD+K
Sbjct: 94 RCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAA 153
Query: 446 NILLTSDGVVKLCDFGFARMISPGES-----YTDYVATRWYRAPELLVGDTMYSTPVDVW 610
N+L+T DGV+KL DFG AR S ++ YT+ V T WYR PELL+G+ Y P+D+W
Sbjct: 154 NVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLW 213
Query: 611 AIXCVFAELLT 643
C+ AE+ T
Sbjct: 214 GAGCIMAEMWT 224
Score = 64.1 bits (149), Expect = 4e-10
Identities = 30/64 (46%), Positives = 46/64 (71%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+ +YEKLAK+G+G++G V+K R+R TG+ VA+KK + + ALREI++L+ LKH
Sbjct: 16 VSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKH 75
Query: 235 PNLV 246
N+V
Sbjct: 76 ENVV 79
>AC007242-1|AAX93182.1| 301|Homo sapiens unknown protein.
Length = 301
Score = 110 bits (264), Expect = 5e-24
Identities = 49/134 (36%), Positives = 79/134 (58%), Gaps = 1/134 (0%)
Frame = +2
Query: 251 LIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
L ++ K L VFEY + + ++P G + ++Q L+G+AY H + +HR
Sbjct: 113 LHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHR 172
Query: 431 DVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYSTPVDV 607
D+KP+N+L++ G +KL DFG AR S P ++Y+ V T WYR P+ L+G T YS+ +D+
Sbjct: 173 DLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDI 232
Query: 608 WAIXCVFAELLTSE 649
W C+F E+ +
Sbjct: 233 WGAGCIFIEMFQGQ 246
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/61 (45%), Positives = 38/61 (62%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y L KLGEGSY VYK +R G++VA+K N ++ + A+RE +LK LKH N+
Sbjct: 52 YLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG-VPFTAIREASLLKGLKHANI 110
Query: 244 V 246
V
Sbjct: 111 V 111
>AB053308-1|BAB69017.1| 384|Homo sapiens ALS2CR7 protein.
Length = 384
Score = 110 bits (264), Expect = 5e-24
Identities = 49/134 (36%), Positives = 79/134 (58%), Gaps = 1/134 (0%)
Frame = +2
Query: 251 LIEVFRRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
L ++ K L VFEY + + ++P G + ++Q L+G+AY H + +HR
Sbjct: 113 LHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHR 172
Query: 431 DVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRWYRAPELLVGDTMYSTPVDV 607
D+KP+N+L++ G +KL DFG AR S P ++Y+ V T WYR P+ L+G T YS+ +D+
Sbjct: 173 DLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDI 232
Query: 608 WAIXCVFAELLTSE 649
W C+F E+ +
Sbjct: 233 WGAGCIFIEMFQGQ 246
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/61 (45%), Positives = 38/61 (62%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y L KLGEGSY VYK +R G++VA+K N ++ + A+RE +LK LKH N+
Sbjct: 52 YLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG-VPFTAIREASLLKGLKHANI 110
Query: 244 V 246
V
Sbjct: 111 V 111
>U07705-1|AAA19595.1| 775|Homo sapiens PITSLRE isoform PBETA22
protein.
Length = 775
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 491 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 548
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 549 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 608
Query: 629 AELLTSE 649
ELLT +
Sbjct: 609 GELLTQK 615
Score = 50.4 bits (115), Expect = 5e-06
Identities = 21/64 (32%), Positives = 42/64 (65%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
++ ++ L ++ EG+YG+VY+ +++ T EIVA+K+ +++ +LREI + +H
Sbjct: 415 VDEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQH 474
Query: 235 PNLV 246
PN+V
Sbjct: 475 PNIV 478
>U07704-1|AAA19594.1| 777|Homo sapiens PITSLRE isoform PBETA21
protein.
Length = 777
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 493 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 550
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 551 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 610
Query: 629 AELLTSE 649
ELLT +
Sbjct: 611 GELLTQK 617
Score = 50.4 bits (115), Expect = 5e-06
Identities = 21/64 (32%), Positives = 42/64 (65%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
++ ++ L ++ EG+YG+VY+ +++ T EIVA+K+ +++ +LREI + +H
Sbjct: 417 VDEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQH 476
Query: 235 PNLV 246
PN+V
Sbjct: 477 PNIV 480
>U04819-1|AAA19585.1| 439|Homo sapiens PITSLRE beta 1 protein.
Length = 439
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 155 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 212
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 213 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 272
Query: 629 AELLTSE 649
ELLT +
Sbjct: 273 GELLTQK 279
Score = 50.4 bits (115), Expect = 5e-06
Identities = 21/64 (32%), Positives = 42/64 (65%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
++ ++ L ++ EG+YG+VY+ +++ T EIVA+K+ +++ +LREI + +H
Sbjct: 79 VDEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKENEGFPITSLREINTILKAQH 138
Query: 235 PNLV 246
PN+V
Sbjct: 139 PNIV 142
>M88563-1|AAB59449.1| 446|Homo sapiens p58 protein kinase protein.
Length = 446
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 162 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 219
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 220 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 279
Query: 629 AELLTSE 649
ELLT +
Sbjct: 280 GELLTQK 286
Score = 49.6 bits (113), Expect = 1e-05
Identities = 21/64 (32%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
++ ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 86 VDEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 145
Query: 235 PNLV 246
PN+V
Sbjct: 146 PNIV 149
>BT019903-1|AAV38706.1| 372|Homo sapiens cyclin-dependent kinase 9
(CDC2-related kinase) protein.
Length = 372
Score = 109 bits (261), Expect = 1e-23
Identities = 52/131 (39%), Positives = 76/131 (58%), Gaps = 5/131 (3%)
Frame = +2
Query: 266 RRKRKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPE 445
R K ++LVF++C+H + L K+++ L G+ Y HR+ +HRD+K
Sbjct: 94 RCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAA 153
Query: 446 NILLTSDGVVKLCDFGFARMISPGES-----YTDYVATRWYRAPELLVGDTMYSTPVDVW 610
N+L+T DGV KL DFG AR S ++ YT+ V T WYR PELL+G+ Y P+D+W
Sbjct: 154 NVLITRDGVPKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLW 213
Query: 611 AIXCVFAELLT 643
C+ AE+ T
Sbjct: 214 GAGCIMAEMWT 224
Score = 64.1 bits (149), Expect = 4e-10
Identities = 30/64 (46%), Positives = 46/64 (71%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+ +YEKLAK+G+G++G V+K R+R TG+ VA+KK + + ALREI++L+ LKH
Sbjct: 16 VSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKH 75
Query: 235 PNLV 246
N+V
Sbjct: 76 ENVV 79
>BC110905-1|AAI10906.1| 397|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 397
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 113 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 170
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 171 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 230
Query: 629 AELLTSE 649
ELLT +
Sbjct: 231 GELLTQK 237
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 37 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 96
Query: 235 PNLV 246
PN+V
Sbjct: 97 PNIV 100
>BC094827-1|AAH94827.1| 475|Homo sapiens CDC2L2 protein protein.
Length = 475
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 191 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 248
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 249 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 308
Query: 629 AELLTSE 649
ELLT +
Sbjct: 309 GELLTQK 315
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 115 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 174
Query: 235 PNLV 246
PN+V
Sbjct: 175 PNIV 178
>BC014464-1|AAH14464.1| 464|Homo sapiens CDC2L2 protein protein.
Length = 464
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 180 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 237
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 238 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 297
Query: 629 AELLTSE 649
ELLT +
Sbjct: 298 GELLTQK 304
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 104 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 163
Query: 235 PNLV 246
PN+V
Sbjct: 164 PNIV 167
>AL031282-7|CAI20033.1| 770|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 770
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 486 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 543
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 544 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 603
Query: 629 AELLTSE 649
ELLT +
Sbjct: 604 GELLTQK 610
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 410 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 469
Query: 235 PNLV 246
PN+V
Sbjct: 470 PNIV 473
>AL031282-6|CAI20032.1| 783|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 783
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 499 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 556
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 557 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 616
Query: 629 AELLTSE 649
ELLT +
Sbjct: 617 GELLTQK 623
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 423 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 482
Query: 235 PNLV 246
PN+V
Sbjct: 483 PNIV 486
>AL031282-5|CAI20034.1| 780|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 780
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 496 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 553
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 554 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 613
Query: 629 AELLTSE 649
ELLT +
Sbjct: 614 GELLTQK 620
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
Query: 235 PNLV 246
PN+V
Sbjct: 480 PNIV 483
>AL031282-4|CAI20031.1| 779|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 779
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 495 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 552
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 553 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 612
Query: 629 AELLTSE 649
ELLT +
Sbjct: 613 GELLTQK 619
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 419 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 478
Query: 235 PNLV 246
PN+V
Sbjct: 479 PNIV 482
>AL031282-3|CAI20030.1| 746|Homo sapiens cell division cycle 2-like
2 (PITSLRE proteins) protein.
Length = 746
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 462 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 519
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 520 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 579
Query: 629 AELLTSE 649
ELLT +
Sbjct: 580 GELLTQK 586
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 386 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 445
Query: 235 PNLV 246
PN+V
Sbjct: 446 PNIV 449
>AF080694-4|AAC95300.1| 768|Homo sapiens PITSLRE protein kinase
beta SV3 isoform protein.
Length = 768
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 484 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 541
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 542 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 601
Query: 629 AELLTSE 649
ELLT +
Sbjct: 602 GELLTQK 608
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 408 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 467
Query: 235 PNLV 246
PN+V
Sbjct: 468 PNIV 471
>AF080694-3|AAC95298.1| 781|Homo sapiens PITSLRE protein kinase
beta SV6 isoform protein.
Length = 781
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 497 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 554
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 555 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 614
Query: 629 AELLTSE 649
ELLT +
Sbjct: 615 GELLTQK 621
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 421 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 480
Query: 235 PNLV 246
PN+V
Sbjct: 481 PNIV 484
>AF080694-2|AAC95297.1| 777|Homo sapiens PITSLRE protein kinase
beta SV2 isoform protein.
Length = 777
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 493 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 550
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 551 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 610
Query: 629 AELLTSE 649
ELLT +
Sbjct: 611 GELLTQK 617
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 417 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 476
Query: 235 PNLV 246
PN+V
Sbjct: 477 PNIV 480
>AF080694-1|AAC95299.1| 778|Homo sapiens PITSLRE protein kinase
beta SV1 isoform protein.
Length = 778
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 494 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 551
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 552 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 611
Query: 629 AELLTSE 649
ELLT +
Sbjct: 612 GELLTQK 618
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 418 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 477
Query: 235 PNLV 246
PN+V
Sbjct: 478 PNIV 481
>AF067523-1|AAC72088.1| 397|Homo sapiens PITSLRE protein kinase
beta SV7 isoform protein.
Length = 397
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 113 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 170
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 171 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 230
Query: 629 AELLTSE 649
ELLT +
Sbjct: 231 GELLTQK 237
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 37 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 96
Query: 235 PNLV 246
PN+V
Sbjct: 97 PNIV 100
>AF067522-1|AAC72087.1| 780|Homo sapiens PITSLRE protein kinase
beta SV6 isoform protein.
Length = 780
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 496 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 553
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 554 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 613
Query: 629 AELLTSE 649
ELLT +
Sbjct: 614 GELLTQK 620
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
Query: 235 PNLV 246
PN+V
Sbjct: 480 PNIV 483
>AF067521-1|AAC72086.1| 767|Homo sapiens PITSLRE protein kinase
beta SV3 isoform protein.
Length = 767
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 483 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 540
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 541 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 600
Query: 629 AELLTSE 649
ELLT +
Sbjct: 601 GELLTQK 607
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 407 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 466
Query: 235 PNLV 246
PN+V
Sbjct: 467 PNIV 470
>AF067520-1|AAC72085.1| 776|Homo sapiens PITSLRE protein kinase
beta SV2 isoform protein.
Length = 776
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 492 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 549
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 550 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 609
Query: 629 AELLTSE 649
ELLT +
Sbjct: 610 GELLTQK 616
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 416 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 475
Query: 235 PNLV 246
PN+V
Sbjct: 476 PNIV 479
>AF067519-1|AAC72084.1| 777|Homo sapiens PITSLRE protein kinase
beta SV1 isoform protein.
Length = 777
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 493 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 550
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 551 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 610
Query: 629 AELLTSE 649
ELLT +
Sbjct: 611 GELLTQK 617
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 417 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 476
Query: 235 PNLV 246
PN+V
Sbjct: 477 PNIV 480
>AF067518-1|AAC72083.1| 397|Homo sapiens PITSLRE protein kinase
beta SV8 isoform protein.
Length = 397
Score = 109 bits (261), Expect = 1e-23
Identities = 56/127 (44%), Positives = 83/127 (65%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 113 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 170
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T+WYRAPELL+G YST VD+W++ C+F
Sbjct: 171 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGCIF 230
Query: 629 AELLTSE 649
ELLT +
Sbjct: 231 GELLTQK 237
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 37 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 96
Query: 235 PNLV 246
PN+V
Sbjct: 97 PNIV 100
>U04824-1|AAA19586.1| 779|Homo sapiens PITSLRE alpha 2-1 protein.
Length = 779
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 495 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 552
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 553 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 612
Query: 629 AELLTSE 649
ELLT +
Sbjct: 613 GELLTQK 619
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 419 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 478
Query: 235 PNLV 246
PN+V
Sbjct: 479 PNIV 482
>U04818-1|AAA19584.1| 562|Homo sapiens PITSLRE alpha 2-4 protein.
Length = 562
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 278 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 335
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 336 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 395
Query: 629 AELLTSE 649
ELLT +
Sbjct: 396 GELLTQK 402
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 202 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 261
Query: 235 PNLV 246
PN+V
Sbjct: 262 PNIV 265
>U04817-1|AAA19583.1| 768|Homo sapiens PITSLRE alpha 2-3 protein.
Length = 768
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 484 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 541
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 542 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 601
Query: 629 AELLTSE 649
ELLT +
Sbjct: 602 GELLTQK 608
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 408 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 467
Query: 235 PNLV 246
PN+V
Sbjct: 468 PNIV 471
>U04816-1|AAA19582.1| 777|Homo sapiens PITSLRE alpha 2-2 protein.
Length = 777
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 493 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 550
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 551 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 610
Query: 629 AELLTSE 649
ELLT +
Sbjct: 611 GELLTQK 617
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 417 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 476
Query: 235 PNLV 246
PN+V
Sbjct: 477 PNIV 480
>U04815-1|AAA19581.1| 461|Homo sapiens PITSLRE alpha 1 protein.
Length = 461
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 177 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 234
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 235 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 294
Query: 629 AELLTSE 649
ELLT +
Sbjct: 295 GELLTQK 301
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 101 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 160
Query: 235 PNLV 246
PN+V
Sbjct: 161 PNIV 164
>M37712-1|AAA36406.1| 439|Homo sapiens p58/GTA protein kinase
protein.
Length = 439
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 155 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 212
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 213 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 272
Query: 629 AELLTSE 649
ELLT +
Sbjct: 273 GELLTQK 279
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 79 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 138
Query: 235 PNLV 246
PN+V
Sbjct: 139 PNIV 142
>BC139777-1|AAI39778.1| 542|Homo sapiens CDC2L2 protein protein.
Length = 542
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 258 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 315
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 316 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 375
Query: 629 AELLTSE 649
ELLT +
Sbjct: 376 GELLTQK 382
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 182 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 241
Query: 235 PNLV 246
PN+V
Sbjct: 242 PNIV 245
>BC062579-1|AAH62579.1| 475|Homo sapiens CDC2L2 protein protein.
Length = 475
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 191 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 248
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 249 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 308
Query: 629 AELLTSE 649
ELLT +
Sbjct: 309 GELLTQK 315
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 115 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 174
Query: 235 PNLV 246
PN+V
Sbjct: 175 PNIV 178
>BC033069-1|AAH33069.1| 508|Homo sapiens CDC2L1 protein protein.
Length = 508
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 224 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 281
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 282 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 341
Query: 629 AELLTSE 649
ELLT +
Sbjct: 342 GELLTQK 348
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 148 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 207
Query: 235 PNLV 246
PN+V
Sbjct: 208 PNIV 211
>AF080683-5|AAC83666.1| 565|Homo sapiens PITSLRE protein kinase
alpha SV11 isoform protein.
Length = 565
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 281 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 338
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 339 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 398
Query: 629 AELLTSE 649
ELLT +
Sbjct: 399 GELLTQK 405
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 205 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 264
Query: 235 PNLV 246
PN+V
Sbjct: 265 PNIV 268
>AF080683-4|AAC83663.1| 738|Homo sapiens PITSLRE protein kinase
alpha SV5 isoform protein.
Length = 738
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 454 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 511
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 512 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 571
Query: 629 AELLTSE 649
ELLT +
Sbjct: 572 GELLTQK 578
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 378 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 437
Query: 235 PNLV 246
PN+V
Sbjct: 438 PNIV 441
>AF080683-3|AAC83665.1| 748|Homo sapiens PITSLRE protein kinase
alpha SV10 isoform protein.
Length = 748
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 464 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 521
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 522 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 581
Query: 629 AELLTSE 649
ELLT +
Sbjct: 582 GELLTQK 588
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 388 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 447
Query: 235 PNLV 246
PN+V
Sbjct: 448 PNIV 451
>AF080683-2|AAC83662.1| 782|Homo sapiens PITSLRE protein kinase
alpha SV1 isoform protein.
Length = 782
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 498 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 555
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 556 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 615
Query: 629 AELLTSE 649
ELLT +
Sbjct: 616 GELLTQK 622
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 422 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 481
Query: 235 PNLV 246
PN+V
Sbjct: 482 PNIV 485
>AF080683-1|AAC83664.1| 755|Homo sapiens PITSLRE protein kinase
alpha SV9 isoform protein.
Length = 755
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 471 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 528
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 529 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 588
Query: 629 AELLTSE 649
ELLT +
Sbjct: 589 GELLTQK 595
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 395 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 454
Query: 235 PNLV 246
PN+V
Sbjct: 455 PNIV 458
>AF067517-1|AAC72082.1| 565|Homo sapiens PITSLRE protein kinase
alpha SV11 isoform protein.
Length = 565
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 281 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 338
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 339 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 398
Query: 629 AELLTSE 649
ELLT +
Sbjct: 399 GELLTQK 405
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 205 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 264
Query: 235 PNLV 246
PN+V
Sbjct: 265 PNIV 268
>AF067516-1|AAC72081.1| 748|Homo sapiens PITSLRE protein kinase
alpha SV10 isoform protein.
Length = 748
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 464 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 521
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 522 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 581
Query: 629 AELLTSE 649
ELLT +
Sbjct: 582 GELLTQK 588
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 388 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 447
Query: 235 PNLV 246
PN+V
Sbjct: 448 PNIV 451
>AF067515-1|AAC72080.1| 795|Homo sapiens PITSLRE protein kinase
alpha SV9 isoform protein.
Length = 795
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 511 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 568
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 569 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 628
Query: 629 AELLTSE 649
ELLT +
Sbjct: 629 GELLTQK 635
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 435 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 494
Query: 235 PNLV 246
PN+V
Sbjct: 495 PNIV 498
>AF067514-1|AAC72079.1| 737|Homo sapiens PITSLRE protein kinase
alpha SV5 isoform protein.
Length = 737
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 453 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 510
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 511 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 570
Query: 629 AELLTSE 649
ELLT +
Sbjct: 571 GELLTQK 577
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 377 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 436
Query: 235 PNLV 246
PN+V
Sbjct: 437 PNIV 440
>AF067513-1|AAC72078.1| 526|Homo sapiens PITSLRE protein kinase
alpha SV4 isoform protein.
Length = 526
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 242 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 299
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 300 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 359
Query: 629 AELLTSE 649
ELLT +
Sbjct: 360 GELLTQK 366
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 166 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 225
Query: 235 PNLV 246
PN+V
Sbjct: 226 PNIV 229
>AF067512-1|AAC72077.1| 782|Homo sapiens PITSLRE protein kinase
alpha SV1 isoform protein.
Length = 782
Score = 107 bits (258), Expect = 3e-23
Identities = 56/127 (44%), Positives = 82/127 (64%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + +HRD+K N+
Sbjct: 498 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILHRDLKTSNL 555
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 556 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 615
Query: 629 AELLTSE 649
ELLT +
Sbjct: 616 GELLTQK 622
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 422 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 481
Query: 235 PNLV 246
PN+V
Sbjct: 482 PNIV 485
>L33801-1|AAA66475.1| 420|Homo sapiens protein kinase protein.
Length = 420
Score = 107 bits (257), Expect = 3e-23
Identities = 52/127 (40%), Positives = 74/127 (58%), Gaps = 4/127 (3%)
Frame = +2
Query: 281 LHLVFEYCDHTVLHELEKYPAG---CPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
L+LV +Y TV Y P + K ++Q + +AY H HRD+KP+N+
Sbjct: 128 LNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNL 187
Query: 452 LLTSD-GVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL D V+KLCDFG A+ + GE Y+ +R+YRAPEL+ G T Y++ +DVW+ CV
Sbjct: 188 LLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVL 247
Query: 629 AELLTSE 649
AELL +
Sbjct: 248 AELLLGQ 254
Score = 43.6 bits (98), Expect = 6e-04
Identities = 20/61 (32%), Positives = 39/61 (63%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y +G GS+G+VY+ + D+GE+VA+KK +++ ++ RE+++++ L H N+
Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQD------KRFKNRELQIMRKLDHCNI 109
Query: 244 V 246
V
Sbjct: 110 V 110
>CR536510-1|CAG38748.1| 420|Homo sapiens GSK3B protein.
Length = 420
Score = 107 bits (257), Expect = 3e-23
Identities = 52/127 (40%), Positives = 74/127 (58%), Gaps = 4/127 (3%)
Frame = +2
Query: 281 LHLVFEYCDHTVLHELEKYPAG---CPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
L+LV +Y TV Y P + K ++Q + +AY H HRD+KP+N+
Sbjct: 128 LNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNL 187
Query: 452 LLTSD-GVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL D V+KLCDFG A+ + GE Y+ +R+YRAPEL+ G T Y++ +DVW+ CV
Sbjct: 188 LLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVL 247
Query: 629 AELLTSE 649
AELL +
Sbjct: 248 AELLLGQ 254
Score = 43.6 bits (98), Expect = 6e-04
Identities = 20/61 (32%), Positives = 39/61 (63%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y +G GS+G+VY+ + D+GE+VA+KK +++ ++ RE+++++ L H N+
Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQD------KRFKNRELQIMRKLDHCNI 109
Query: 244 V 246
V
Sbjct: 110 V 110
>BC012760-1|AAH12760.1| 420|Homo sapiens GSK3B protein protein.
Length = 420
Score = 107 bits (257), Expect = 3e-23
Identities = 52/127 (40%), Positives = 74/127 (58%), Gaps = 4/127 (3%)
Frame = +2
Query: 281 LHLVFEYCDHTVLHELEKYPAG---CPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
L+LV +Y TV Y P + K ++Q + +AY H HRD+KP+N+
Sbjct: 128 LNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNL 187
Query: 452 LLTSD-GVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL D V+KLCDFG A+ + GE Y+ +R+YRAPEL+ G T Y++ +DVW+ CV
Sbjct: 188 LLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVL 247
Query: 629 AELLTSE 649
AELL +
Sbjct: 248 AELLLGQ 254
Score = 43.6 bits (98), Expect = 6e-04
Identities = 20/61 (32%), Positives = 39/61 (63%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y +G GS+G+VY+ + D+GE+VA+KK +++ ++ RE+++++ L H N+
Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQD------KRFKNRELQIMRKLDHCNI 109
Query: 244 V 246
V
Sbjct: 110 V 110
>BC000251-1|AAH00251.1| 433|Homo sapiens glycogen synthase kinase 3
beta protein.
Length = 433
Score = 107 bits (257), Expect = 3e-23
Identities = 52/127 (40%), Positives = 74/127 (58%), Gaps = 4/127 (3%)
Frame = +2
Query: 281 LHLVFEYCDHTVLHELEKYPAG---CPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
L+LV +Y TV Y P + K ++Q + +AY H HRD+KP+N+
Sbjct: 128 LNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNL 187
Query: 452 LLTSD-GVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL D V+KLCDFG A+ + GE Y+ +R+YRAPEL+ G T Y++ +DVW+ CV
Sbjct: 188 LLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVL 247
Query: 629 AELLTSE 649
AELL +
Sbjct: 248 AELLLGQ 254
Score = 43.6 bits (98), Expect = 6e-04
Identities = 20/61 (32%), Positives = 39/61 (63%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y +G GS+G+VY+ + D+GE+VA+KK +++ ++ RE+++++ L H N+
Sbjct: 56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQD------KRFKNRELQIMRKLDHCNI 109
Query: 244 V 246
V
Sbjct: 110 V 110
>L40027-1|AAA62432.1| 483|Homo sapiens glycogen synthase kinase 3
protein.
Length = 483
Score = 107 bits (256), Expect = 5e-23
Identities = 53/127 (41%), Positives = 74/127 (58%), Gaps = 4/127 (3%)
Frame = +2
Query: 281 LHLVFEYCDHTVLH---ELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
L+LV EY TV K P L K ++Q + +AY H HRD+KP+N+
Sbjct: 191 LNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNL 250
Query: 452 LLTSD-GVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
L+ D V+KLCDFG A+ + GE Y+ +R+YRAPEL+ G T Y++ +DVW+ CV
Sbjct: 251 LVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVL 310
Query: 629 AELLTSE 649
AELL +
Sbjct: 311 AELLLGQ 317
Score = 43.6 bits (98), Expect = 6e-04
Identities = 20/61 (32%), Positives = 39/61 (63%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y + +G GS+G+VY+ R +T E+VA+KK +++ ++ RE+++++ L H N+
Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQD------KRFKNRELQIMRKLDHCNI 172
Query: 244 V 246
V
Sbjct: 173 V 173
>D63424-1|BAA23608.1| 483|Homo sapiens glycogen synthase kinase
3alpha protein.
Length = 483
Score = 107 bits (256), Expect = 5e-23
Identities = 53/127 (41%), Positives = 74/127 (58%), Gaps = 4/127 (3%)
Frame = +2
Query: 281 LHLVFEYCDHTVLH---ELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
L+LV EY TV K P L K ++Q + +AY H HRD+KP+N+
Sbjct: 191 LNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNL 250
Query: 452 LLTSD-GVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
L+ D V+KLCDFG A+ + GE Y+ +R+YRAPEL+ G T Y++ +DVW+ CV
Sbjct: 251 LVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVL 310
Query: 629 AELLTSE 649
AELL +
Sbjct: 311 AELLLGQ 317
Score = 43.6 bits (98), Expect = 6e-04
Identities = 20/61 (32%), Positives = 39/61 (63%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y + +G GS+G+VY+ R +T E+VA+KK +++ ++ RE+++++ L H N+
Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQD------KRFKNRELQIMRKLDHCNI 172
Query: 244 V 246
V
Sbjct: 173 V 173
>BC051865-1|AAH51865.1| 483|Homo sapiens glycogen synthase kinase 3
alpha protein.
Length = 483
Score = 107 bits (256), Expect = 5e-23
Identities = 53/127 (41%), Positives = 74/127 (58%), Gaps = 4/127 (3%)
Frame = +2
Query: 281 LHLVFEYCDHTVLH---ELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
L+LV EY TV K P L K ++Q + +AY H HRD+KP+N+
Sbjct: 191 LNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNL 250
Query: 452 LLTSD-GVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
L+ D V+KLCDFG A+ + GE Y+ +R+YRAPEL+ G T Y++ +DVW+ CV
Sbjct: 251 LVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVL 310
Query: 629 AELLTSE 649
AELL +
Sbjct: 311 AELLLGQ 317
Score = 43.6 bits (98), Expect = 6e-04
Identities = 20/61 (32%), Positives = 39/61 (63%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y + +G GS+G+VY+ R +T E+VA+KK +++ ++ RE+++++ L H N+
Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQD------KRFKNRELQIMRKLDHCNI 172
Query: 244 V 246
V
Sbjct: 173 V 173
>BC040529-1|AAH40529.1| 231|Homo sapiens PCTK3 protein protein.
Length = 231
Score = 107 bits (256), Expect = 5e-23
Identities = 43/91 (47%), Positives = 65/91 (71%), Gaps = 1/91 (1%)
Frame = +2
Query: 374 IWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRW 550
++Q L+G+AYCH +HRD+KP+N+L+ G +KL DFG AR S P ++Y++ V T W
Sbjct: 1 MFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLW 60
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLT 643
YR P++L+G T YSTP+D+W + C+ E+ T
Sbjct: 61 YRPPDVLLGSTEYSTPIDMWGVGCIHYEMAT 91
>BC027984-1|AAH27984.1| 483|Homo sapiens glycogen synthase kinase 3
alpha protein.
Length = 483
Score = 107 bits (256), Expect = 5e-23
Identities = 53/127 (41%), Positives = 74/127 (58%), Gaps = 4/127 (3%)
Frame = +2
Query: 281 LHLVFEYCDHTVLH---ELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
L+LV EY TV K P L K ++Q + +AY H HRD+KP+N+
Sbjct: 191 LNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNL 250
Query: 452 LLTSD-GVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
L+ D V+KLCDFG A+ + GE Y+ +R+YRAPEL+ G T Y++ +DVW+ CV
Sbjct: 251 LVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVL 310
Query: 629 AELLTSE 649
AELL +
Sbjct: 311 AELLLGQ 317
Score = 43.6 bits (98), Expect = 6e-04
Identities = 20/61 (32%), Positives = 39/61 (63%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y + +G GS+G+VY+ R +T E+VA+KK +++ ++ RE+++++ L H N+
Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQD------KRFKNRELQIMRKLDHCNI 172
Query: 244 V 246
V
Sbjct: 173 V 173
>AC006486-1|AAD11986.1| 483|Homo sapiens KG3A_HUMAN protein.
Length = 483
Score = 107 bits (256), Expect = 5e-23
Identities = 53/127 (41%), Positives = 74/127 (58%), Gaps = 4/127 (3%)
Frame = +2
Query: 281 LHLVFEYCDHTVLH---ELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
L+LV EY TV K P L K ++Q + +AY H HRD+KP+N+
Sbjct: 191 LNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQGVCHRDIKPQNL 250
Query: 452 LLTSD-GVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
L+ D V+KLCDFG A+ + GE Y+ +R+YRAPEL+ G T Y++ +DVW+ CV
Sbjct: 251 LVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVL 310
Query: 629 AELLTSE 649
AELL +
Sbjct: 311 AELLLGQ 317
Score = 43.6 bits (98), Expect = 6e-04
Identities = 20/61 (32%), Positives = 39/61 (63%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y + +G GS+G+VY+ R +T E+VA+KK +++ ++ RE+++++ L H N+
Sbjct: 119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQD------KRFKNRELQIMRKLDHCNI 172
Query: 244 V 246
V
Sbjct: 173 V 173
>AY994058-1|AAY44299.1| 254|Homo sapiens extracellular regulated
kinase 8 delta protein.
Length = 254
Score = 105 bits (251), Expect = 2e-22
Identities = 52/141 (36%), Positives = 86/141 (60%), Gaps = 8/141 (5%)
Frame = +2
Query: 242 LFNLIEVFRRK--RKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRH 415
+ +L++V R + R ++LVFE+ D T L+ + + ++ + I +Q L+ + H
Sbjct: 73 IISLLDVIRAENDRDIYLVFEFMD-TDLNAVIRKGGLLQDVRVRSIFYQLLRATRFLHSG 131
Query: 416 NCIHRDVKPENILLTSDGVVKLCDFGFARMISP------GESYTDYVATRWYRAPELLVG 577
+ +HRD KP N+LL ++ VKLCDFG AR + ++ T+YVATRWYRAPE+L+
Sbjct: 132 HVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLS 191
Query: 578 DTMYSTPVDVWAIXCVFAELL 640
Y+ VD+W++ C+ E+L
Sbjct: 192 SHRYTLGVDMWSLGCILGEML 212
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/65 (38%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNL-K 231
+ RY +LG+G+YG+V+K +R TGE+VA+KK + D + REI +L+
Sbjct: 10 VRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFGD 69
Query: 232 HPNLV 246
HPN++
Sbjct: 70 HPNII 74
>AY065978-1|AAL40897.1| 544|Homo sapiens extracellular
signal-regulated kinase 8 protein.
Length = 544
Score = 104 bits (250), Expect = 2e-22
Identities = 52/141 (36%), Positives = 86/141 (60%), Gaps = 8/141 (5%)
Frame = +2
Query: 242 LFNLIEVFRRK--RKLHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRH 415
+ +L++V R + R ++LVFE+ D T L+ + + ++ + I +Q L+ + H
Sbjct: 73 IISLLDVIRAENDRDIYLVFEFMD-TDLNAVIRKGGLLQDVHVRSIFYQLLRATRFLHSG 131
Query: 416 NCIHRDVKPENILLTSDGVVKLCDFGFARMISP------GESYTDYVATRWYRAPELLVG 577
+ +HRD KP N+LL ++ VKLCDFG AR + ++ T+YVATRWYRAPE+L+
Sbjct: 132 HVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLS 191
Query: 578 DTMYSTPVDVWAIXCVFAELL 640
Y+ VD+W++ C+ E+L
Sbjct: 192 SHRYTLGVDMWSLGCILGEML 212
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/65 (38%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNL-K 231
+ RY +LG+G+YG+V+K +R TGE+VA+KK + D + REI +L+
Sbjct: 10 VRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFGD 69
Query: 232 HPNLV 246
HPN++
Sbjct: 70 HPNII 74
>Z11695-1|CAA77753.1| 348|Homo sapiens 40kDa protein kinase
protein.
Length = 348
Score = 103 bits (247), Expect = 6e-22
Identities = 41/95 (43%), Positives = 66/95 (69%), Gaps = 4/95 (4%)
Frame = +2
Query: 374 IWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESY----TDYVA 541
++Q L+G+ Y H N +HRD+KP N+LL + +K+CDFG AR+ P + T+YVA
Sbjct: 118 LYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVA 177
Query: 542 TRWYRAPELLVGDTMYSTPVDVWAIXCVFAELLTS 646
TRWYRAPE+++ Y+ +D+W++ C+ AE+L++
Sbjct: 178 TRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN 212
Score = 41.5 bits (93), Expect = 0.003
Identities = 22/65 (33%), Positives = 35/65 (53%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPN 240
RY L+ +GEG+YG+V + VA+KK E ++ LREI++L +H N
Sbjct: 12 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQR-TLREIKILLRFRHEN 70
Query: 241 LV*FN 255
++ N
Sbjct: 71 IIGIN 75
>Z11694-1|CAA77752.1| 360|Homo sapiens 41kD protein kinase protein.
Length = 360
Score = 103 bits (247), Expect = 6e-22
Identities = 41/95 (43%), Positives = 66/95 (69%), Gaps = 4/95 (4%)
Frame = +2
Query: 374 IWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESY----TDYVA 541
++Q L+G+ Y H N +HRD+KP N+LL + +K+CDFG AR+ P + T+YVA
Sbjct: 130 LYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVA 189
Query: 542 TRWYRAPELLVGDTMYSTPVDVWAIXCVFAELLTS 646
TRWYRAPE+++ Y+ +D+W++ C+ AE+L++
Sbjct: 190 TRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN 224
Score = 41.5 bits (93), Expect = 0.003
Identities = 22/65 (33%), Positives = 35/65 (53%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPN 240
RY L+ +GEG+YG+V + VA+KK E ++ LREI++L +H N
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQR-TLREIKILLRFRHEN 82
Query: 241 LV*FN 255
++ N
Sbjct: 83 IIGIN 87
>M84489-1|AAA58459.1| 360|Homo sapiens protein kinase 2 protein.
Length = 360
Score = 103 bits (247), Expect = 6e-22
Identities = 41/95 (43%), Positives = 66/95 (69%), Gaps = 4/95 (4%)
Frame = +2
Query: 374 IWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESY----TDYVA 541
++Q L+G+ Y H N +HRD+KP N+LL + +K+CDFG AR+ P + T+YVA
Sbjct: 130 LYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVA 189
Query: 542 TRWYRAPELLVGDTMYSTPVDVWAIXCVFAELLTS 646
TRWYRAPE+++ Y+ +D+W++ C+ AE+L++
Sbjct: 190 TRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN 224
Score = 41.5 bits (93), Expect = 0.003
Identities = 22/65 (33%), Positives = 35/65 (53%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPN 240
RY L+ +GEG+YG+V + VA+KK E ++ LREI++L +H N
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQR-TLREIKILLRFRHEN 82
Query: 241 LV*FN 255
++ N
Sbjct: 83 IIGIN 87
>DQ508104-1|ABF47102.1| 360|Homo sapiens mitogen-activated protein
kinase 1 protein.
Length = 360
Score = 103 bits (247), Expect = 6e-22
Identities = 41/95 (43%), Positives = 66/95 (69%), Gaps = 4/95 (4%)
Frame = +2
Query: 374 IWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESY----TDYVA 541
++Q L+G+ Y H N +HRD+KP N+LL + +K+CDFG AR+ P + T+YVA
Sbjct: 130 LYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVA 189
Query: 542 TRWYRAPELLVGDTMYSTPVDVWAIXCVFAELLTS 646
TRWYRAPE+++ Y+ +D+W++ C+ AE+L++
Sbjct: 190 TRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN 224
Score = 41.5 bits (93), Expect = 0.003
Identities = 22/65 (33%), Positives = 35/65 (53%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPN 240
RY L+ +GEG+YG+V + VA+KK E ++ LREI++L +H N
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQR-TLREIKILLRFRHEN 82
Query: 241 LV*FN 255
++ N
Sbjct: 83 IIGIN 87
>BC017832-1|AAH17832.1| 360|Homo sapiens mitogen-activated protein
kinase 1 protein.
Length = 360
Score = 103 bits (247), Expect = 6e-22
Identities = 41/95 (43%), Positives = 66/95 (69%), Gaps = 4/95 (4%)
Frame = +2
Query: 374 IWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESY----TDYVA 541
++Q L+G+ Y H N +HRD+KP N+LL + +K+CDFG AR+ P + T+YVA
Sbjct: 130 LYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVA 189
Query: 542 TRWYRAPELLVGDTMYSTPVDVWAIXCVFAELLTS 646
TRWYRAPE+++ Y+ +D+W++ C+ AE+L++
Sbjct: 190 TRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN 224
Score = 41.5 bits (93), Expect = 0.003
Identities = 22/65 (33%), Positives = 35/65 (53%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPN 240
RY L+ +GEG+YG+V + VA+KK E ++ LREI++L +H N
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQR-TLREIKILLRFRHEN 82
Query: 241 LV*FN 255
++ N
Sbjct: 83 IIGIN 87
>Z11696-1|CAA77754.1| 355|Homo sapiens 44kDa protein kinase
protein.
Length = 355
Score = 102 bits (244), Expect = 1e-21
Identities = 40/95 (42%), Positives = 66/95 (69%), Gaps = 4/95 (4%)
Frame = +2
Query: 374 IWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESY----TDYVA 541
++Q L+G+ Y H N +HRD+KP N+L+ + +K+CDFG AR+ P + T+YVA
Sbjct: 123 LYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVA 182
Query: 542 TRWYRAPELLVGDTMYSTPVDVWAIXCVFAELLTS 646
TRWYRAPE+++ Y+ +D+W++ C+ AE+L++
Sbjct: 183 TRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN 217
Score = 39.5 bits (88), Expect = 0.010
Identities = 21/62 (33%), Positives = 34/62 (54%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPN 240
RY +L +GEG+YG+V + VA+KK E ++ LREI++L +H N
Sbjct: 17 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQR-TLREIQILLRFRHEN 75
Query: 241 LV 246
++
Sbjct: 76 VI 77
>M84490-1|AAA36142.1| 366|Homo sapiens kinase 1 protein.
Length = 366
Score = 102 bits (244), Expect = 1e-21
Identities = 40/95 (42%), Positives = 66/95 (69%), Gaps = 4/95 (4%)
Frame = +2
Query: 374 IWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESY----TDYVA 541
++Q L+G+ Y H N +HRD+KP N+L+ + +K+CDFG AR+ P + T+YVA
Sbjct: 134 LYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVA 193
Query: 542 TRWYRAPELLVGDTMYSTPVDVWAIXCVFAELLTS 646
TRWYRAPE+++ Y+ +D+W++ C+ AE+L++
Sbjct: 194 TRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN 228
Score = 39.5 bits (88), Expect = 0.010
Identities = 21/62 (33%), Positives = 34/62 (54%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPN 240
RY +L +GEG+YG+V + VA+KK E ++ LREI++L +H N
Sbjct: 28 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQR-TLREIQILLRFRHEN 86
Query: 241 LV 246
++
Sbjct: 87 VI 88
>BX537897-1|CAD97888.1| 323|Homo sapiens hypothetical protein
protein.
Length = 323
Score = 102 bits (244), Expect = 1e-21
Identities = 40/95 (42%), Positives = 66/95 (69%), Gaps = 4/95 (4%)
Frame = +2
Query: 374 IWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESY----TDYVA 541
++Q L+G+ Y H N +HRD+KP N+L+ + +K+CDFG AR+ P + T+YVA
Sbjct: 91 LYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVA 150
Query: 542 TRWYRAPELLVGDTMYSTPVDVWAIXCVFAELLTS 646
TRWYRAPE+++ Y+ +D+W++ C+ AE+L++
Sbjct: 151 TRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN 185
>BC013992-1|AAH13992.1| 379|Homo sapiens mitogen-activated protein
kinase 3 protein.
Length = 379
Score = 102 bits (244), Expect = 1e-21
Identities = 40/95 (42%), Positives = 66/95 (69%), Gaps = 4/95 (4%)
Frame = +2
Query: 374 IWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESY----TDYVA 541
++Q L+G+ Y H N +HRD+KP N+L+ + +K+CDFG AR+ P + T+YVA
Sbjct: 147 LYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVA 206
Query: 542 TRWYRAPELLVGDTMYSTPVDVWAIXCVFAELLTS 646
TRWYRAPE+++ Y+ +D+W++ C+ AE+L++
Sbjct: 207 TRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN 241
Score = 39.5 bits (88), Expect = 0.010
Identities = 21/62 (33%), Positives = 34/62 (54%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPN 240
RY +L +GEG+YG+V + VA+KK E ++ LREI++L +H N
Sbjct: 41 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQR-TLREIQILLRFRHEN 99
Query: 241 LV 246
++
Sbjct: 100 VI 101
>AF174497-1|AAF36538.1| 565|Homo sapiens GR AF-1 coactivator 3
protein.
Length = 565
Score = 102 bits (244), Expect = 1e-21
Identities = 54/127 (42%), Positives = 80/127 (62%), Gaps = 3/127 (2%)
Frame = +2
Query: 278 KLHLVFEYCDHTV--LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENI 451
K+++V Y +H + L E K P E+ K ++ Q L+GV + H + + RD+K +
Sbjct: 281 KIYIVMNYVEHDLKSLMETMKQPFLPGEV--KTLMIQLLRGVKHLHDNWILQRDLKTSTL 338
Query: 452 LLTSDGVVKLCDFGFARMI-SPGESYTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
LL+ G++K+ DFG AR SP ++YT V T WYRAPELL+G YST VD+W++ C+F
Sbjct: 339 LLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIF 398
Query: 629 AELLTSE 649
ELLT +
Sbjct: 399 GELLTQK 405
Score = 50.8 bits (116), Expect = 4e-06
Identities = 22/64 (34%), Positives = 41/64 (64%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKH 234
+E ++ L ++ EG+YG+VY+ +++ T EIVA+K+ ++ +LREI + +H
Sbjct: 205 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 264
Query: 235 PNLV 246
PN+V
Sbjct: 265 PNIV 268
>DQ316259-1|ABC40748.1| 516|Homo sapiens nemo like kinase protein.
Length = 516
Score = 101 bits (243), Expect = 2e-21
Identities = 47/110 (42%), Positives = 70/110 (63%), Gaps = 2/110 (1%)
Frame = +2
Query: 317 LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGF 496
LH++ P K ++Q L+G+ Y H +HRD+KP N+L+ S+ V+K+CDFG
Sbjct: 215 LHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGL 274
Query: 497 ARMISPGES--YTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAELL 640
AR+ ES T V T++YRAPE+L+G YS +D+W++ C+FAELL
Sbjct: 275 ARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELL 324
Score = 32.7 bits (71), Expect = 1.2
Identities = 17/55 (30%), Positives = 31/55 (56%)
Frame = +1
Query: 82 LGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNLV 246
+G G++G+V+ + G+ VA+KK + + K RE++ML KH N++
Sbjct: 133 IGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVL 187
>BC099905-1|AAH99905.1| 360|Homo sapiens mitogen-activated protein
kinase 1 protein.
Length = 360
Score = 101 bits (243), Expect = 2e-21
Identities = 40/95 (42%), Positives = 66/95 (69%), Gaps = 4/95 (4%)
Frame = +2
Query: 374 IWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESY----TDYVA 541
++Q L+G+ Y H N +HRD+KP N+LL + +++CDFG AR+ P + T+YVA
Sbjct: 130 LYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLEICDFGLARVADPDHDHTGFLTEYVA 189
Query: 542 TRWYRAPELLVGDTMYSTPVDVWAIXCVFAELLTS 646
TRWYRAPE+++ Y+ +D+W++ C+ AE+L++
Sbjct: 190 TRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN 224
Score = 40.7 bits (91), Expect = 0.004
Identities = 22/65 (33%), Positives = 35/65 (53%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPN 240
RY L+ +GEG+YG+V + VA+KK E ++ LREI++L +H N
Sbjct: 24 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQR-TLREIKILLRSRHEN 82
Query: 241 LV*FN 255
++ N
Sbjct: 83 IIGIN 87
>BC064663-1|AAH64663.1| 515|Homo sapiens nemo-like kinase protein.
Length = 515
Score = 101 bits (243), Expect = 2e-21
Identities = 47/110 (42%), Positives = 70/110 (63%), Gaps = 2/110 (1%)
Frame = +2
Query: 317 LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGF 496
LH++ P K ++Q L+G+ Y H +HRD+KP N+L+ S+ V+K+CDFG
Sbjct: 214 LHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGL 273
Query: 497 ARMISPGES--YTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAELL 640
AR+ ES T V T++YRAPE+L+G YS +D+W++ C+FAELL
Sbjct: 274 ARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELL 323
Score = 32.7 bits (71), Expect = 1.2
Identities = 17/55 (30%), Positives = 31/55 (56%)
Frame = +1
Query: 82 LGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNLV 246
+G G++G+V+ + G+ VA+KK + + K RE++ML KH N++
Sbjct: 132 IGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVL 186
>AF197898-1|AAF04857.1| 515|Homo sapiens nemo-like kinase protein.
Length = 515
Score = 101 bits (243), Expect = 2e-21
Identities = 47/110 (42%), Positives = 70/110 (63%), Gaps = 2/110 (1%)
Frame = +2
Query: 317 LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGF 496
LH++ P K ++Q L+G+ Y H +HRD+KP N+L+ S+ V+K+CDFG
Sbjct: 214 LHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGL 273
Query: 497 ARMISPGES--YTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAELL 640
AR+ ES T V T++YRAPE+L+G YS +D+W++ C+FAELL
Sbjct: 274 ARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELL 323
Score = 32.7 bits (71), Expect = 1.2
Identities = 17/55 (30%), Positives = 31/55 (56%)
Frame = +1
Query: 82 LGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNLV 246
+G G++G+V+ + G+ VA+KK + + K RE++ML KH N++
Sbjct: 132 IGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVL 186
>AF180819-1|AAD56013.1| 515|Homo sapiens LAK1 protein protein.
Length = 515
Score = 101 bits (243), Expect = 2e-21
Identities = 47/110 (42%), Positives = 70/110 (63%), Gaps = 2/110 (1%)
Frame = +2
Query: 317 LHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGF 496
LH++ P K ++Q L+G+ Y H +HRD+KP N+L+ S+ V+K+CDFG
Sbjct: 214 LHKIIVSPQPLSSDHVKVFLYQILRGLKYLHSAGILHRDIKPGNLLVNSNCVLKICDFGL 273
Query: 497 ARMISPGES--YTDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAELL 640
AR+ ES T V T++YRAPE+L+G YS +D+W++ C+FAELL
Sbjct: 274 ARVEELDESRHMTQEVVTQYYRAPEILMGSRHYSNAIDIWSVGCIFAELL 323
Score = 32.7 bits (71), Expect = 1.2
Identities = 17/55 (30%), Positives = 31/55 (56%)
Frame = +1
Query: 82 LGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNLV 246
+G G++G+V+ + G+ VA+KK + + K RE++ML KH N++
Sbjct: 132 IGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDNVL 186
>X60188-1|CAA42744.1| 379|Homo sapiens protein serine/threonine
kinase protein.
Length = 379
Score = 100 bits (240), Expect = 4e-21
Identities = 40/95 (42%), Positives = 65/95 (68%), Gaps = 4/95 (4%)
Frame = +2
Query: 374 IWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYT----DYVA 541
++Q L+G+ Y H N +HRD+KP N+L + +K+CDFG AR+ P +T +YVA
Sbjct: 147 LYQILRGLKYIHSANVLHRDLKPSNLLSNTTCDLKICDFGLARIADPEHDHTGFLTEYVA 206
Query: 542 TRWYRAPELLVGDTMYSTPVDVWAIXCVFAELLTS 646
TRWYRAPE+++ Y+ +D+W++ C+ AE+L++
Sbjct: 207 TRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN 241
Score = 39.5 bits (88), Expect = 0.010
Identities = 21/62 (33%), Positives = 34/62 (54%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPN 240
RY +L +GEG+YG+V + VA+KK E ++ LREI++L +H N
Sbjct: 41 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQR-TLREIQILLRFRHEN 99
Query: 241 LV 246
++
Sbjct: 100 VI 101
>AY033608-1|AAK52330.1| 335|Homo sapiens extracellular
signal-related kinase 1c protein.
Length = 335
Score = 100 bits (240), Expect = 4e-21
Identities = 40/95 (42%), Positives = 65/95 (68%), Gaps = 4/95 (4%)
Frame = +2
Query: 374 IWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYT----DYVA 541
++Q L+G+ Y H N +HRD+KP N+L + +K+CDFG AR+ P +T +YVA
Sbjct: 147 LYQILRGLKYIHSANVLHRDLKPSNLLSNTTCDLKICDFGLARIADPEHDHTGFLTEYVA 206
Query: 542 TRWYRAPELLVGDTMYSTPVDVWAIXCVFAELLTS 646
TRWYRAPE+++ Y+ +D+W++ C+ AE+L++
Sbjct: 207 TRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN 241
Score = 39.5 bits (88), Expect = 0.010
Identities = 21/62 (33%), Positives = 34/62 (54%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPN 240
RY +L +GEG+YG+V + VA+KK E ++ LREI++L +H N
Sbjct: 41 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQR-TLREIQILLRFRHEN 99
Query: 241 LV 246
++
Sbjct: 100 VI 101
>AY033607-1|AAK52329.1| 357|Homo sapiens extracellular
signal-related kinase 1b protein.
Length = 357
Score = 100 bits (240), Expect = 4e-21
Identities = 40/95 (42%), Positives = 65/95 (68%), Gaps = 4/95 (4%)
Frame = +2
Query: 374 IWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYT----DYVA 541
++Q L+G+ Y H N +HRD+KP N+L + +K+CDFG AR+ P +T +YVA
Sbjct: 147 LYQILRGLKYIHSANVLHRDLKPSNLLSNTTCDLKICDFGLARIADPEHDHTGFLTEYVA 206
Query: 542 TRWYRAPELLVGDTMYSTPVDVWAIXCVFAELLTS 646
TRWYRAPE+++ Y+ +D+W++ C+ AE+L++
Sbjct: 207 TRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSN 241
Score = 39.5 bits (88), Expect = 0.010
Identities = 21/62 (33%), Positives = 34/62 (54%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPN 240
RY +L +GEG+YG+V + VA+KK E ++ LREI++L +H N
Sbjct: 41 RYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQR-TLREIQILLRFRHEN 99
Query: 241 LV 246
++
Sbjct: 100 VI 101
>BC053536-1|AAH53536.1| 231|Homo sapiens RAGE protein protein.
Length = 231
Score = 99.1 bits (236), Expect = 1e-20
Identities = 51/129 (39%), Positives = 77/129 (59%), Gaps = 3/129 (2%)
Frame = +2
Query: 260 VFRRKR-KLHLVFEYCDHTVLHELE--KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
VF RK L L+ E D + + +YP +++ ++Q + + + HR+ HR
Sbjct: 70 VFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIM--HYMYQLCKSLDHIHRNGIFHR 127
Query: 431 DVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVW 610
DVKPENIL+ D V+KL DFG R + + YT+Y++TRWYRAPE L+ D Y+ +D+W
Sbjct: 128 DVKPENILIKQD-VLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYKMDLW 186
Query: 611 AIXCVFAEL 637
+ CVF E+
Sbjct: 187 SAGCVFYEI 195
Score = 36.3 bits (80), Expect = 0.095
Identities = 20/65 (30%), Positives = 38/65 (58%), Gaps = 1/65 (1%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLK- 231
M+ Y+ + K+GEG++ V K ++ G A K+ ++ + + + LREI+ L+ L
Sbjct: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQ-MKQRFESIEQVNNLREIQALRRLNP 59
Query: 232 HPNLV 246
HPN++
Sbjct: 60 HPNIL 64
>AB022694-1|BAA81688.1| 419|Homo sapiens MOK protein kinase
protein.
Length = 419
Score = 99.1 bits (236), Expect = 1e-20
Identities = 51/129 (39%), Positives = 77/129 (59%), Gaps = 3/129 (2%)
Frame = +2
Query: 260 VFRRKR-KLHLVFEYCDHTVLHELE--KYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHR 430
VF RK L L+ E D + + +YP +++ ++Q + + + HR+ HR
Sbjct: 70 VFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIM--HYMYQLCKSLDHIHRNGIFHR 127
Query: 431 DVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYSTPVDVW 610
DVKPENIL+ D V+KL DFG R + + YT+Y++TRWYRAPE L+ D Y+ +D+W
Sbjct: 128 DVKPENILIKQD-VLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYKMDLW 186
Query: 611 AIXCVFAEL 637
+ CVF E+
Sbjct: 187 SAGCVFYEI 195
Score = 36.3 bits (80), Expect = 0.095
Identities = 20/65 (30%), Positives = 38/65 (58%), Gaps = 1/65 (1%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLK- 231
M+ Y+ + K+GEG++ V K ++ G A K+ ++ + + + LREI+ L+ L
Sbjct: 1 MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQ-MKQRFESIEQVNNLREIQALRRLNP 59
Query: 232 HPNLV 246
HPN++
Sbjct: 60 HPNIL 64
>AK131512-1|BAD18656.1| 345|Homo sapiens protein ( Homo sapiens
cDNA FLJ16732 fis, clone BNGH42005017, moderately
similar to SERINE/THREONINE-PROTEIN KINASE PCTAIRE-1 (EC
2.7.1.-). ).
Length = 345
Score = 97.5 bits (232), Expect = 4e-20
Identities = 40/93 (43%), Positives = 63/93 (67%), Gaps = 1/93 (1%)
Frame = +2
Query: 374 IWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMIS-PGESYTDYVATRW 550
++Q L+G+AY H + +HRD+KP+N+L++ G +KL DFG AR S P ++Y+ V T W
Sbjct: 184 MFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLW 243
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLTSE 649
YR P+ L+G T YS+ +D+W C+F E+ +
Sbjct: 244 YRPPDALLGATEYSSELDIWGAGCIFIEMFQGQ 276
Score = 52.4 bits (120), Expect = 1e-06
Identities = 28/61 (45%), Positives = 38/61 (62%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y L KLGEGSY VYK +R G++VA+K N ++ + A+RE +LK LKH N+
Sbjct: 103 YLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEG-VPFTAIREASLLKGLKHANI 161
Query: 244 V 246
V
Sbjct: 162 V 162
>Z95152-5|CAO03649.1| 360|Homo sapiens mitogen-activated protein
kinase 14 protein.
Length = 360
Score = 97.1 bits (231), Expect = 5e-20
Identities = 42/91 (46%), Positives = 61/91 (67%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+I+Q L+G+ Y H + IHRD+KP N+ + D +K+ DFG AR + T YVATRW
Sbjct: 130 LIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD--DEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLT 643
YRAPE+++ Y+ VD+W++ C+ AELLT
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLT 218
Score = 50.0 bits (114), Expect = 7e-06
Identities = 25/63 (39%), Positives = 37/63 (58%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
ERY+ L+ +G G+YG V + TG VAVKK + K RE+R+LK++KH
Sbjct: 22 ERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>Y14440-1|CAA74792.1| 364|Homo sapiens stress activated protein
kinase-2b protein.
Length = 364
Score = 97.1 bits (231), Expect = 5e-20
Identities = 41/94 (43%), Positives = 61/94 (64%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+++Q L+G+ Y H IHRD+KP N+ + D +++ DFG AR E T YVATRW
Sbjct: 130 LVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQAD--EEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLTSEA 652
YRAPE+++ Y+ VD+W++ C+ AELL +A
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKA 221
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/63 (33%), Positives = 34/63 (53%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
+R + L +G G+YG V + + VAVKK + + RE+R+LK+LKH
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>U92268-1|AAB66313.1| 364|Homo sapiens mitogen activated protein
kinase p38-2 protein.
Length = 364
Score = 97.1 bits (231), Expect = 5e-20
Identities = 41/94 (43%), Positives = 61/94 (64%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+++Q L+G+ Y H IHRD+KP N+ + D +++ DFG AR E T YVATRW
Sbjct: 130 LVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQAD--EEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLTSEA 652
YRAPE+++ Y+ VD+W++ C+ AELL +A
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKA 221
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/63 (33%), Positives = 34/63 (53%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
+R + L +G G+YG V + + VAVKK + + RE+R+LK+LKH
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>U53442-1|AAB05036.1| 372|Homo sapiens p38Beta MAP kinase protein.
Length = 372
Score = 97.1 bits (231), Expect = 5e-20
Identities = 41/94 (43%), Positives = 61/94 (64%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+++Q L+G+ Y H IHRD+KP N+ + D +++ DFG AR E T YVATRW
Sbjct: 138 LVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQAD--EEMTGYVATRW 195
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLTSEA 652
YRAPE+++ Y+ VD+W++ C+ AELL +A
Sbjct: 196 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKA 229
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/63 (33%), Positives = 34/63 (53%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
+R + L +G G+YG V + + VAVKK + + RE+R+LK+LKH
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>U19775-1|AAC50329.1| 297|Homo sapiens Mxi2 protein.
Length = 297
Score = 97.1 bits (231), Expect = 5e-20
Identities = 42/91 (46%), Positives = 61/91 (67%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+I+Q L+G+ Y H + IHRD+KP N+ + D +K+ DFG AR + T YVATRW
Sbjct: 130 LIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD--DEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLT 643
YRAPE+++ Y+ VD+W++ C+ AELLT
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLT 218
Score = 50.0 bits (114), Expect = 7e-06
Identities = 25/63 (39%), Positives = 37/63 (58%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
ERY+ L+ +G G+YG V + TG VAVKK + K RE+R+LK++KH
Sbjct: 22 ERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>L35264-1|AAA57456.1| 360|Homo sapiens CSaids binding protein
protein.
Length = 360
Score = 97.1 bits (231), Expect = 5e-20
Identities = 42/91 (46%), Positives = 61/91 (67%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+I+Q L+G+ Y H + IHRD+KP N+ + D +K+ DFG AR + T YVATRW
Sbjct: 130 LIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD--DEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLT 643
YRAPE+++ Y+ VD+W++ C+ AELLT
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLT 218
Score = 50.0 bits (114), Expect = 7e-06
Identities = 25/63 (39%), Positives = 37/63 (58%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
ERY+ L+ +G G+YG V + TG VAVKK + K RE+R+LK++KH
Sbjct: 22 ERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>L35263-1|AAA57455.1| 360|Homo sapiens CSaids binding protein
protein.
Length = 360
Score = 97.1 bits (231), Expect = 5e-20
Identities = 42/91 (46%), Positives = 61/91 (67%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+I+Q L+G+ Y H + IHRD+KP N+ + D +K+ DFG AR + T YVATRW
Sbjct: 130 LIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD--DEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLT 643
YRAPE+++ Y+ VD+W++ C+ AELLT
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLT 218
Score = 50.0 bits (114), Expect = 7e-06
Identities = 25/63 (39%), Positives = 37/63 (58%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
ERY+ L+ +G G+YG V + TG VAVKK + K RE+R+LK++KH
Sbjct: 22 ERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>L35253-1|AAA74301.1| 360|Homo sapiens MAP kinase protein.
Length = 360
Score = 97.1 bits (231), Expect = 5e-20
Identities = 42/91 (46%), Positives = 61/91 (67%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+I+Q L+G+ Y H + IHRD+KP N+ + D +K+ DFG AR + T YVATRW
Sbjct: 130 LIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD--DEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLT 643
YRAPE+++ Y+ VD+W++ C+ AELLT
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLT 218
Score = 50.0 bits (114), Expect = 7e-06
Identities = 25/63 (39%), Positives = 37/63 (58%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
ERY+ L+ +G G+YG V + TG VAVKK + K RE+R+LK++KH
Sbjct: 22 ERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>DQ279722-1|ABB72677.1| 364|Homo sapiens mitogen-activated protein
kinase 11 protein.
Length = 364
Score = 97.1 bits (231), Expect = 5e-20
Identities = 41/94 (43%), Positives = 61/94 (64%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+++Q L+G+ Y H IHRD+KP N+ + D +++ DFG AR E T YVATRW
Sbjct: 130 LVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQAD--EEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLTSEA 652
YRAPE+++ Y+ VD+W++ C+ AELL +A
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKA 221
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/63 (33%), Positives = 34/63 (53%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
+R + L +G G+YG V + + VAVKK + + RE+R+LK+LKH
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>CR536505-1|CAG38743.1| 360|Homo sapiens MAPK14 protein.
Length = 360
Score = 97.1 bits (231), Expect = 5e-20
Identities = 42/91 (46%), Positives = 61/91 (67%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+I+Q L+G+ Y H + IHRD+KP N+ + D +K+ DFG AR + T YVATRW
Sbjct: 130 LIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD--DEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLT 643
YRAPE+++ Y+ VD+W++ C+ AELLT
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLT 218
Score = 50.0 bits (114), Expect = 7e-06
Identities = 25/63 (39%), Positives = 37/63 (58%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
ERY+ L+ +G G+YG V + TG VAVKK + K RE+R+LK++KH
Sbjct: 22 ERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>CR456514-1|CAG30400.1| 364|Homo sapiens MAPK11 protein.
Length = 364
Score = 97.1 bits (231), Expect = 5e-20
Identities = 41/94 (43%), Positives = 61/94 (64%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+++Q L+G+ Y H IHRD+KP N+ + D +++ DFG AR E T YVATRW
Sbjct: 130 LVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQAD--EEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLTSEA 652
YRAPE+++ Y+ VD+W++ C+ AELL +A
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKA 221
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/63 (33%), Positives = 34/63 (53%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
+R + L +G G+YG V + + VAVKK + + RE+R+LK+LKH
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>BT006933-1|AAP35579.1| 360|Homo sapiens mitogen-activated protein
kinase 14 protein.
Length = 360
Score = 97.1 bits (231), Expect = 5e-20
Identities = 42/91 (46%), Positives = 61/91 (67%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+I+Q L+G+ Y H + IHRD+KP N+ + D +K+ DFG AR + T YVATRW
Sbjct: 130 LIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD--DEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLT 643
YRAPE+++ Y+ VD+W++ C+ AELLT
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLT 218
Score = 50.0 bits (114), Expect = 7e-06
Identities = 25/63 (39%), Positives = 37/63 (58%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
ERY+ L+ +G G+YG V + TG VAVKK + K RE+R+LK++KH
Sbjct: 22 ERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>BC031574-1|AAH31574.1| 360|Homo sapiens mitogen-activated protein
kinase 14 protein.
Length = 360
Score = 97.1 bits (231), Expect = 5e-20
Identities = 42/91 (46%), Positives = 61/91 (67%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+I+Q L+G+ Y H + IHRD+KP N+ + D +K+ DFG AR + T YVATRW
Sbjct: 130 LIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD--DEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLT 643
YRAPE+++ Y+ VD+W++ C+ AELLT
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLT 218
Score = 50.0 bits (114), Expect = 7e-06
Identities = 25/63 (39%), Positives = 37/63 (58%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
ERY+ L+ +G G+YG V + TG VAVKK + K RE+R+LK++KH
Sbjct: 22 ERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>BC027933-1|AAH27933.1| 364|Homo sapiens mitogen-activated protein
kinase 11 protein.
Length = 364
Score = 97.1 bits (231), Expect = 5e-20
Identities = 41/94 (43%), Positives = 61/94 (64%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+++Q L+G+ Y H IHRD+KP N+ + D +++ DFG AR E T YVATRW
Sbjct: 130 LVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQAD--EEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLTSEA 652
YRAPE+++ Y+ VD+W++ C+ AELL +A
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKA 221
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/63 (33%), Positives = 34/63 (53%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
+R + L +G G+YG V + + VAVKK + + RE+R+LK+LKH
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>BC000092-1|AAH00092.1| 360|Homo sapiens mitogen-activated protein
kinase 14 protein.
Length = 360
Score = 97.1 bits (231), Expect = 5e-20
Identities = 42/91 (46%), Positives = 61/91 (67%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+I+Q L+G+ Y H + IHRD+KP N+ + D +K+ DFG AR + T YVATRW
Sbjct: 130 LIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD--DEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLT 643
YRAPE+++ Y+ VD+W++ C+ AELLT
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLT 218
Score = 50.0 bits (114), Expect = 7e-06
Identities = 25/63 (39%), Positives = 37/63 (58%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
ERY+ L+ +G G+YG V + TG VAVKK + K RE+R+LK++KH
Sbjct: 22 ERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>AL022328-13|CAB51539.1| 364|Homo sapiens mitogen-activated protein
kinase 11 protein.
Length = 364
Score = 97.1 bits (231), Expect = 5e-20
Identities = 41/94 (43%), Positives = 61/94 (64%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+++Q L+G+ Y H IHRD+KP N+ + D +++ DFG AR E T YVATRW
Sbjct: 130 LVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQAD--EEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLTSEA 652
YRAPE+++ Y+ VD+W++ C+ AELL +A
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKA 221
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/63 (33%), Positives = 34/63 (53%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
+R + L +G G+YG V + + VAVKK + + RE+R+LK+LKH
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>AF100544-1|AAF36770.1| 360|Homo sapiens stress-activated protein
kinase 2a protein.
Length = 360
Score = 97.1 bits (231), Expect = 5e-20
Identities = 42/91 (46%), Positives = 61/91 (67%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+I+Q L+G+ Y H + IHRD+KP N+ + D +K+ DFG AR + T YVATRW
Sbjct: 130 LIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD--DEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLT 643
YRAPE+++ Y+ VD+W++ C+ AELLT
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLT 218
Score = 50.0 bits (114), Expect = 7e-06
Identities = 25/63 (39%), Positives = 37/63 (58%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
ERY+ L+ +G G+YG V + TG VAVKK + K RE+R+LK++KH
Sbjct: 22 ERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>AF031135-1|AAC12714.1| 364|Homo sapiens p38beta2 MAP kinase
protein.
Length = 364
Score = 97.1 bits (231), Expect = 5e-20
Identities = 41/94 (43%), Positives = 61/94 (64%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+++Q L+G+ Y H IHRD+KP N+ + D +++ DFG AR E T YVATRW
Sbjct: 130 LVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQAD--EEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLTSEA 652
YRAPE+++ Y+ VD+W++ C+ AELL +A
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKA 221
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/63 (33%), Positives = 34/63 (53%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
+R + L +G G+YG V + + VAVKK + + RE+R+LK+LKH
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>AF001174-1|AAC51373.1| 364|Homo sapiens p38beta2 MAP kinase
protein.
Length = 364
Score = 97.1 bits (231), Expect = 5e-20
Identities = 41/94 (43%), Positives = 61/94 (64%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+++Q L+G+ Y H IHRD+KP N+ + D +++ DFG AR E T YVATRW
Sbjct: 130 LVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQAD--EEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLTSEA 652
YRAPE+++ Y+ VD+W++ C+ AELL +A
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKA 221
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/63 (33%), Positives = 34/63 (53%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
+R + L +G G+YG V + + VAVKK + + RE+R+LK+LKH
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>AF001008-1|AAC51250.1| 364|Homo sapiens p38Beta2 MAP Kinase
protein.
Length = 364
Score = 97.1 bits (231), Expect = 5e-20
Identities = 41/94 (43%), Positives = 61/94 (64%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+++Q L+G+ Y H IHRD+KP N+ + D +++ DFG AR E T YVATRW
Sbjct: 130 LVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQAD--EEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLTSEA 652
YRAPE+++ Y+ VD+W++ C+ AELL +A
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKA 221
Score = 40.3 bits (90), Expect = 0.006
Identities = 21/63 (33%), Positives = 34/63 (53%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
+R + L +G G+YG V + + VAVKK + + RE+R+LK+LKH
Sbjct: 22 QRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>AB074150-1|BAB85654.1| 307|Homo sapiens Alternative spliced
variant of p38alpha EXIP protein.
Length = 307
Score = 97.1 bits (231), Expect = 5e-20
Identities = 42/91 (46%), Positives = 61/91 (67%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+I+Q L+G+ Y H + IHRD+KP N+ + D +K+ DFG AR + T YVATRW
Sbjct: 130 LIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTD--DEMTGYVATRW 187
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLT 643
YRAPE+++ Y+ VD+W++ C+ AELLT
Sbjct: 188 YRAPEIMLNWMHYNQTVDIWSVGCIMAELLT 218
Score = 50.0 bits (114), Expect = 7e-06
Identities = 25/63 (39%), Positives = 37/63 (58%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
ERY+ L+ +G G+YG V + TG VAVKK + K RE+R+LK++KH
Sbjct: 22 ERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHE 81
Query: 238 NLV 246
N++
Sbjct: 82 NVI 84
>X80692-1|CAA56709.1| 721|Homo sapiens p97mapk protein.
Length = 721
Score = 96.3 bits (229), Expect = 8e-20
Identities = 47/128 (36%), Positives = 81/128 (63%), Gaps = 5/128 (3%)
Frame = +2
Query: 281 LHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENILL- 457
+++V EY + + + LE+ P E ++ ++Q L+G+ Y H N +HRD+KP N+ +
Sbjct: 104 VYIVQEYMETDLANVLEQGPL--LEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFIN 161
Query: 458 TSDGVVKLCDFGFARMISPGESYTDYVA----TRWYRAPELLVGDTMYSTPVDVWAIXCV 625
T D V+K+ DFG AR++ P S+ +++ T+WYR+P LL+ Y+ +D+WA C+
Sbjct: 162 TEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCI 221
Query: 626 FAELLTSE 649
FAE+LT +
Sbjct: 222 FAEMLTGK 229
Score = 46.8 bits (106), Expect = 7e-05
Identities = 27/62 (43%), Positives = 36/62 (58%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPN 240
RY L LG G GLV+ + D + VA+KK V DP K ALREI++++ L H N
Sbjct: 19 RYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLT--DPQSVKHALREIKIIRRLDHDN 76
Query: 241 LV 246
+V
Sbjct: 77 IV 78
>L77964-1|AAA98769.1| 721|Homo sapiens ERK3 protein kinase protein.
Length = 721
Score = 96.3 bits (229), Expect = 8e-20
Identities = 47/128 (36%), Positives = 81/128 (63%), Gaps = 5/128 (3%)
Frame = +2
Query: 281 LHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENILL- 457
+++V EY + + + LE+ P E ++ ++Q L+G+ Y H N +HRD+KP N+ +
Sbjct: 104 VYIVQEYMETDLANVLEQGPL--LEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFIN 161
Query: 458 TSDGVVKLCDFGFARMISPGESYTDYVA----TRWYRAPELLVGDTMYSTPVDVWAIXCV 625
T D V+K+ DFG AR++ P S+ +++ T+WYR+P LL+ Y+ +D+WA C+
Sbjct: 162 TEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCI 221
Query: 626 FAELLTSE 649
FAE+LT +
Sbjct: 222 FAEMLTGK 229
Score = 46.8 bits (106), Expect = 7e-05
Identities = 27/62 (43%), Positives = 36/62 (58%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPN 240
RY L LG G GLV+ + D + VA+KK V DP K ALREI++++ L H N
Sbjct: 19 RYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLT--DPQSVKHALREIKIIRRLDHDN 76
Query: 241 LV 246
+V
Sbjct: 77 IV 78
>BC035492-1|AAH35492.1| 721|Homo sapiens mitogen-activated protein
kinase 6 protein.
Length = 721
Score = 96.3 bits (229), Expect = 8e-20
Identities = 47/128 (36%), Positives = 81/128 (63%), Gaps = 5/128 (3%)
Frame = +2
Query: 281 LHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENILL- 457
+++V EY + + + LE+ P E ++ ++Q L+G+ Y H N +HRD+KP N+ +
Sbjct: 104 VYIVQEYMETDLANVLEQGPL--LEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFIN 161
Query: 458 TSDGVVKLCDFGFARMISPGESYTDYVA----TRWYRAPELLVGDTMYSTPVDVWAIXCV 625
T D V+K+ DFG AR++ P S+ +++ T+WYR+P LL+ Y+ +D+WA C+
Sbjct: 162 TEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCI 221
Query: 626 FAELLTSE 649
FAE+LT +
Sbjct: 222 FAEMLTGK 229
Score = 46.8 bits (106), Expect = 7e-05
Identities = 27/62 (43%), Positives = 36/62 (58%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPN 240
RY L LG G GLV+ + D + VA+KK V DP K ALREI++++ L H N
Sbjct: 19 RYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLT--DPQSVKHALREIKIIRRLDHDN 76
Query: 241 LV 246
+V
Sbjct: 77 IV 78
>AF420474-1|AAL17605.1| 721|Homo sapiens ERK-3 protein.
Length = 721
Score = 96.3 bits (229), Expect = 8e-20
Identities = 47/128 (36%), Positives = 81/128 (63%), Gaps = 5/128 (3%)
Frame = +2
Query: 281 LHLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENILL- 457
+++V EY + + + LE+ P E ++ ++Q L+G+ Y H N +HRD+KP N+ +
Sbjct: 104 VYIVQEYMETDLANVLEQGPL--LEEHARLFMYQLLRGLKYIHSANVLHRDLKPANLFIN 161
Query: 458 TSDGVVKLCDFGFARMISPGESYTDYVA----TRWYRAPELLVGDTMYSTPVDVWAIXCV 625
T D V+K+ DFG AR++ P S+ +++ T+WYR+P LL+ Y+ +D+WA C+
Sbjct: 162 TEDLVLKIGDFGLARIMDPHYSHKGHLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCI 221
Query: 626 FAELLTSE 649
FAE+LT +
Sbjct: 222 FAEMLTGK 229
Score = 46.8 bits (106), Expect = 7e-05
Identities = 27/62 (43%), Positives = 36/62 (58%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPN 240
RY L LG G GLV+ + D + VA+KK V DP K ALREI++++ L H N
Sbjct: 19 RYMDLKPLGCGGNGLVFSAVDNDCDKRVAIKKIVLT--DPQSVKHALREIKIIRRLDHDN 76
Query: 241 LV 246
+V
Sbjct: 77 IV 78
>BC028034-1|AAH28034.1| 277|Homo sapiens MAPK15 protein protein.
Length = 277
Score = 94.7 bits (225), Expect = 3e-19
Identities = 41/98 (41%), Positives = 62/98 (63%), Gaps = 6/98 (6%)
Frame = +2
Query: 365 KQIIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISP------GESY 526
+ I +Q L+ + H + +HRD KP N+LL ++ VKLCDFG AR + ++
Sbjct: 132 RSIFYQLLRATRFLHSGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAV 191
Query: 527 TDYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAELL 640
T+YVATRWYRAPE+L+ Y+ VD+W++ C+ E+L
Sbjct: 192 TEYVATRWYRAPEVLLSSHRYTLGVDMWSLGCILGEML 229
Score = 51.6 bits (118), Expect = 2e-06
Identities = 25/65 (38%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Frame = +1
Query: 55 MERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNL-K 231
+ RY +LG+G+YG+V+K +R TGE+VA+KK + D + REI +L+
Sbjct: 10 VRRYLLRRQLGQGAYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQRTFREITLLQEFGD 69
Query: 232 HPNLV 246
HPN++
Sbjct: 70 HPNII 74
>D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein.
Length = 766
Score = 94.3 bits (224), Expect = 3e-19
Identities = 46/138 (33%), Positives = 78/138 (56%), Gaps = 2/138 (1%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHE-LEKYPAGCPELLSKQIIWQTLQGVAYCHRHN 418
+ L EV + KL+L+ E D + + + K+ G E L+K+ Q + ++YCH+ +
Sbjct: 76 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 135
Query: 419 CIHRDVKPENILL-TSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYST 595
+HRD+KPEN++ G+VKL DFGF+ PG+ T + Y APE+L+GD +
Sbjct: 136 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAP 195
Query: 596 PVDVWAIXCVFAELLTSE 649
VD+W++ + L+ +
Sbjct: 196 AVDIWSLGVILFMLVCGQ 213
Score = 40.3 bits (90), Expect = 0.006
Identities = 22/61 (36%), Positives = 34/61 (55%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y+ LG G + +V R+ TGE VAVK + + D L +E+R +K ++HPN+
Sbjct: 17 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHPNI 76
Query: 244 V 246
V
Sbjct: 77 V 77
>BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein.
Length = 765
Score = 94.3 bits (224), Expect = 3e-19
Identities = 46/138 (33%), Positives = 78/138 (56%), Gaps = 2/138 (1%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHE-LEKYPAGCPELLSKQIIWQTLQGVAYCHRHN 418
+ L EV + KL+L+ E D + + + K+ G E L+K+ Q + ++YCH+ +
Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134
Query: 419 CIHRDVKPENILL-TSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYST 595
+HRD+KPEN++ G+VKL DFGF+ PG+ T + Y APE+L+GD +
Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAP 194
Query: 596 PVDVWAIXCVFAELLTSE 649
VD+W++ + L+ +
Sbjct: 195 AVDIWSLGVILFMLVCGQ 212
Score = 40.3 bits (90), Expect = 0.006
Identities = 22/61 (36%), Positives = 34/61 (55%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y+ LG G + +V R+ TGE VAVK + + D L +E+R +K ++HPN+
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHPNI 75
Query: 244 V 246
V
Sbjct: 76 V 76
>AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens
cDNA FLJ20224 fis, clone COLF5039. ).
Length = 244
Score = 94.3 bits (224), Expect = 3e-19
Identities = 46/138 (33%), Positives = 78/138 (56%), Gaps = 2/138 (1%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHE-LEKYPAGCPELLSKQIIWQTLQGVAYCHRHN 418
+ L EV + KL+L+ E D + + + K+ G E L+K+ Q + ++YCH+ +
Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLH 134
Query: 419 CIHRDVKPENILL-TSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYST 595
+HRD+KPEN++ G+VKL DFGF+ PG+ T + Y APE+L+GD +
Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAP 194
Query: 596 PVDVWAIXCVFAELLTSE 649
VD+W++ + L+ +
Sbjct: 195 AVDIWSLGVILFMLVCEQ 212
Score = 40.3 bits (90), Expect = 0.006
Identities = 22/61 (36%), Positives = 34/61 (55%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y+ LG G + +V R+ TGE VAVK + + D L +E+R +K ++HPN+
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHPNI 75
Query: 244 V 246
V
Sbjct: 76 V 76
>AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein.
Length = 765
Score = 94.3 bits (224), Expect = 3e-19
Identities = 46/138 (33%), Positives = 77/138 (55%), Gaps = 2/138 (1%)
Frame = +2
Query: 242 LFNLIEVFRRKRKLHLVFEYCDHTVLHE-LEKYPAGCPELLSKQIIWQTLQGVAYCHRHN 418
+ L EV + KL+L+ E D + + + K+ G E L K+ Q + ++YCH+ +
Sbjct: 75 IVRLYEVIDTQTKLYLILELGDEGDMFDYIMKHEEGLNEDLPKKYFAQIVHAISYCHKLH 134
Query: 419 CIHRDVKPENILL-TSDGVVKLCDFGFARMISPGESYTDYVATRWYRAPELLVGDTMYST 595
+HRD+KPEN++ G+VKL DFGF+ PG+ T + Y APE+L+GD +
Sbjct: 135 VVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAP 194
Query: 596 PVDVWAIXCVFAELLTSE 649
VD+W++ + L+ +
Sbjct: 195 AVDIWSLGVILFMLVCGQ 212
Score = 40.3 bits (90), Expect = 0.006
Identities = 22/61 (36%), Positives = 34/61 (55%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y+ LG G + +V R+ TGE VAVK + + D L +E+R +K ++HPN+
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHPNI 75
Query: 244 V 246
V
Sbjct: 76 V 76
>U29727-1|AAA82933.1| 816|Homo sapiens BMK1 gamma kinase protein.
Length = 816
Score = 93.1 bits (221), Expect = 8e-19
Identities = 42/97 (43%), Positives = 64/97 (65%), Gaps = 5/97 (5%)
Frame = +2
Query: 365 KQIIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMI--SPGESY---T 529
+ ++Q L+G+ Y H IHRD+KP N+L+ + +K+ DFG AR + SP E T
Sbjct: 160 RYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMT 219
Query: 530 DYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAELL 640
+YVATRWYRAPEL++ Y+ +D+W++ C+F E+L
Sbjct: 220 EYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEML 256
Score = 53.2 bits (122), Expect = 8e-07
Identities = 25/63 (39%), Positives = 38/63 (60%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
+ YE + +G G+YG+V R R TG+ VA+KK D K LRE+++LK+ KH
Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHD 112
Query: 238 NLV 246
N++
Sbjct: 113 NII 115
>U29726-1|AAA82932.1| 816|Homo sapiens BMK1 beta kinase protein.
Length = 816
Score = 93.1 bits (221), Expect = 8e-19
Identities = 42/97 (43%), Positives = 64/97 (65%), Gaps = 5/97 (5%)
Frame = +2
Query: 365 KQIIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMI--SPGESY---T 529
+ ++Q L+G+ Y H IHRD+KP N+L+ + +K+ DFG AR + SP E T
Sbjct: 160 RYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMT 219
Query: 530 DYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAELL 640
+YVATRWYRAPEL++ Y+ +D+W++ C+F E+L
Sbjct: 220 EYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEML 256
Score = 53.2 bits (122), Expect = 8e-07
Identities = 25/63 (39%), Positives = 38/63 (60%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
+ YE + +G G+YG+V R R TG+ VA+KK D K LRE+++LK+ KH
Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHD 112
Query: 238 NLV 246
N++
Sbjct: 113 NII 115
>U29725-1|AAA82931.1| 816|Homo sapiens BMK1 alpha kinase protein.
Length = 816
Score = 93.1 bits (221), Expect = 8e-19
Identities = 42/97 (43%), Positives = 64/97 (65%), Gaps = 5/97 (5%)
Frame = +2
Query: 365 KQIIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMI--SPGESY---T 529
+ ++Q L+G+ Y H IHRD+KP N+L+ + +K+ DFG AR + SP E T
Sbjct: 160 RYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMT 219
Query: 530 DYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAELL 640
+YVATRWYRAPEL++ Y+ +D+W++ C+F E+L
Sbjct: 220 EYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEML 256
Score = 53.2 bits (122), Expect = 8e-07
Identities = 25/63 (39%), Positives = 38/63 (60%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
+ YE + +G G+YG+V R R TG+ VA+KK D K LRE+++LK+ KH
Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHD 112
Query: 238 NLV 246
N++
Sbjct: 113 NII 115
>U25278-1|AAA81381.1| 815|Homo sapiens ERK5 protein.
Length = 815
Score = 93.1 bits (221), Expect = 8e-19
Identities = 42/97 (43%), Positives = 64/97 (65%), Gaps = 5/97 (5%)
Frame = +2
Query: 365 KQIIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMI--SPGESY---T 529
+ ++Q L+G+ Y H IHRD+KP N+L+ + +K+ DFG AR + SP E T
Sbjct: 159 RYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMT 218
Query: 530 DYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAELL 640
+YVATRWYRAPEL++ Y+ +D+W++ C+F E+L
Sbjct: 219 EYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEML 255
Score = 53.2 bits (122), Expect = 8e-07
Identities = 25/63 (39%), Positives = 38/63 (60%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
+ YE + +G G+YG+V R R TG+ VA+KK D K LRE+++LK+ KH
Sbjct: 52 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHD 111
Query: 238 NLV 246
N++
Sbjct: 112 NII 114
>BC030134-1|AAH30134.1| 816|Homo sapiens mitogen-activated protein
kinase 7 protein.
Length = 816
Score = 93.1 bits (221), Expect = 8e-19
Identities = 42/97 (43%), Positives = 64/97 (65%), Gaps = 5/97 (5%)
Frame = +2
Query: 365 KQIIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMI--SPGESY---T 529
+ ++Q L+G+ Y H IHRD+KP N+L+ + +K+ DFG AR + SP E T
Sbjct: 160 RYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMT 219
Query: 530 DYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAELL 640
+YVATRWYRAPEL++ Y+ +D+W++ C+F E+L
Sbjct: 220 EYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEML 256
Score = 53.2 bits (122), Expect = 8e-07
Identities = 25/63 (39%), Positives = 38/63 (60%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
+ YE + +G G+YG+V R R TG+ VA+KK D K LRE+++LK+ KH
Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHD 112
Query: 238 NLV 246
N++
Sbjct: 113 NII 115
>BC009963-1|AAH09963.1| 816|Homo sapiens mitogen-activated protein
kinase 7 protein.
Length = 816
Score = 93.1 bits (221), Expect = 8e-19
Identities = 42/97 (43%), Positives = 64/97 (65%), Gaps = 5/97 (5%)
Frame = +2
Query: 365 KQIIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMI--SPGESY---T 529
+ ++Q L+G+ Y H IHRD+KP N+L+ + +K+ DFG AR + SP E T
Sbjct: 160 RYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMT 219
Query: 530 DYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAELL 640
+YVATRWYRAPEL++ Y+ +D+W++ C+F E+L
Sbjct: 220 EYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEML 256
Score = 53.2 bits (122), Expect = 8e-07
Identities = 25/63 (39%), Positives = 38/63 (60%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
+ YE + +G G+YG+V R R TG+ VA+KK D K LRE+++LK+ KH
Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHD 112
Query: 238 NLV 246
N++
Sbjct: 113 NII 115
>BC007992-1|AAH07992.1| 677|Homo sapiens mitogen-activated protein
kinase 7 protein.
Length = 677
Score = 93.1 bits (221), Expect = 8e-19
Identities = 42/97 (43%), Positives = 64/97 (65%), Gaps = 5/97 (5%)
Frame = +2
Query: 365 KQIIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMI--SPGESY---T 529
+ ++Q L+G+ Y H IHRD+KP N+L+ + +K+ DFG AR + SP E T
Sbjct: 21 RYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMT 80
Query: 530 DYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAELL 640
+YVATRWYRAPEL++ Y+ +D+W++ C+F E+L
Sbjct: 81 EYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEML 117
>BC007404-1|AAH07404.1| 677|Homo sapiens mitogen-activated protein
kinase 7 protein.
Length = 677
Score = 93.1 bits (221), Expect = 8e-19
Identities = 42/97 (43%), Positives = 64/97 (65%), Gaps = 5/97 (5%)
Frame = +2
Query: 365 KQIIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMI--SPGESY---T 529
+ ++Q L+G+ Y H IHRD+KP N+L+ + +K+ DFG AR + SP E T
Sbjct: 21 RYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMT 80
Query: 530 DYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAELL 640
+YVATRWYRAPEL++ Y+ +D+W++ C+F E+L
Sbjct: 81 EYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEML 117
>AY534741-1|AAS38577.1| 533|Homo sapiens mitogen activated protein
kinase 7 transcript variant 5 protein.
Length = 533
Score = 93.1 bits (221), Expect = 8e-19
Identities = 42/97 (43%), Positives = 64/97 (65%), Gaps = 5/97 (5%)
Frame = +2
Query: 365 KQIIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMI--SPGESY---T 529
+ ++Q L+G+ Y H IHRD+KP N+L+ + +K+ DFG AR + SP E T
Sbjct: 160 RYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMT 219
Query: 530 DYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAELL 640
+YVATRWYRAPEL++ Y+ +D+W++ C+F E+L
Sbjct: 220 EYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEML 256
Score = 53.2 bits (122), Expect = 8e-07
Identities = 25/63 (39%), Positives = 38/63 (60%)
Frame = +1
Query: 58 ERYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHP 237
+ YE + +G G+YG+V R R TG+ VA+KK D K LRE+++LK+ KH
Sbjct: 53 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHD 112
Query: 238 NLV 246
N++
Sbjct: 113 NII 115
>AB209611-1|BAD92848.1| 453|Homo sapiens Mitogen activated protein
kinase 7 transcript variant 5 variant protein.
Length = 453
Score = 93.1 bits (221), Expect = 8e-19
Identities = 42/97 (43%), Positives = 64/97 (65%), Gaps = 5/97 (5%)
Frame = +2
Query: 365 KQIIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMI--SPGESY---T 529
+ ++Q L+G+ Y H IHRD+KP N+L+ + +K+ DFG AR + SP E T
Sbjct: 80 RYFLYQLLRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMT 139
Query: 530 DYVATRWYRAPELLVGDTMYSTPVDVWAIXCVFAELL 640
+YVATRWYRAPEL++ Y+ +D+W++ C+F E+L
Sbjct: 140 EYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEML 176
>Y10487-1|CAA71511.1| 367|Homo sapiens stress-activated protein
kinase-3 protein.
Length = 367
Score = 92.7 bits (220), Expect = 1e-18
Identities = 38/93 (40%), Positives = 59/93 (63%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+++Q L+G+ Y H IHRD+KP N+ + D +K+ DFG AR T YV TRW
Sbjct: 133 LVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQAD--SEMTGYVVTRW 190
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLTSE 649
YRAPE+++ Y+ VD+W++ C+ AE++T +
Sbjct: 191 YRAPEVILNWMRYTQTVDIWSVGCIMAEMITGK 223
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/61 (37%), Positives = 34/61 (55%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y L +G G+YG V + TG VA+KK L K A RE+R+LK+++H N+
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENV 86
Query: 244 V 246
+
Sbjct: 87 I 87
>U66243-1|AAB40118.1| 367|Homo sapiens p38gamma MAP Kinase protein.
Length = 367
Score = 92.7 bits (220), Expect = 1e-18
Identities = 38/93 (40%), Positives = 59/93 (63%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+++Q L+G+ Y H IHRD+KP N+ + D +K+ DFG AR T YV TRW
Sbjct: 133 LVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQAD--SEMTGYVVTRW 190
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLTSE 649
YRAPE+++ Y+ VD+W++ C+ AE++T +
Sbjct: 191 YRAPEVILNWMRYTQTVDIWSVGCIMAEMITGK 223
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/61 (37%), Positives = 34/61 (55%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y L +G G+YG V + TG VA+KK L K A RE+R+LK+++H N+
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENV 86
Query: 244 V 246
+
Sbjct: 87 I 87
>BC015741-1|AAH15741.1| 367|Homo sapiens mitogen-activated protein
kinase 12 protein.
Length = 367
Score = 92.7 bits (220), Expect = 1e-18
Identities = 38/93 (40%), Positives = 59/93 (63%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+++Q L+G+ Y H IHRD+KP N+ + D +K+ DFG AR T YV TRW
Sbjct: 133 LVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQAD--SEMTGYVVTRW 190
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLTSE 649
YRAPE+++ Y+ VD+W++ C+ AE++T +
Sbjct: 191 YRAPEVILNWMRYTQTVDIWSVGCIMAEMITGK 223
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/61 (37%), Positives = 34/61 (55%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y L +G G+YG V + TG VA+KK L K A RE+R+LK+++H N+
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENV 86
Query: 244 V 246
+
Sbjct: 87 I 87
>AL022328-12|CAB51538.1| 367|Homo sapiens mitogen-activated protein
kinase 12 protein.
Length = 367
Score = 92.7 bits (220), Expect = 1e-18
Identities = 38/93 (40%), Positives = 59/93 (63%)
Frame = +2
Query: 371 IIWQTLQGVAYCHRHNCIHRDVKPENILLTSDGVVKLCDFGFARMISPGESYTDYVATRW 550
+++Q L+G+ Y H IHRD+KP N+ + D +K+ DFG AR T YV TRW
Sbjct: 133 LVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQAD--SEMTGYVVTRW 190
Query: 551 YRAPELLVGDTMYSTPVDVWAIXCVFAELLTSE 649
YRAPE+++ Y+ VD+W++ C+ AE++T +
Sbjct: 191 YRAPEVILNWMRYTQTVDIWSVGCIMAEMITGK 223
Score = 48.0 bits (109), Expect = 3e-05
Identities = 23/61 (37%), Positives = 34/61 (55%)
Frame = +1
Query: 64 YEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPNL 243
Y L +G G+YG V + TG VA+KK L K A RE+R+LK+++H N+
Sbjct: 27 YRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYRPFQSELFAKRAYRELRLLKHMRHENV 86
Query: 244 V 246
+
Sbjct: 87 I 87
>X59727-1|CAA42411.1| 557|Homo sapiens 63kDa protein kinase
protein.
Length = 557
Score = 92.3 bits (219), Expect = 1e-18
Identities = 47/125 (37%), Positives = 75/125 (60%), Gaps = 5/125 (4%)
Frame = +2
Query: 284 HLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENILL-T 460
++V EY + + LE+ E +K ++Q L+G+ Y H N +HRD+KP NI + T
Sbjct: 102 YIVQEYMETDLARLLEQ--GTLAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFIST 159
Query: 461 SDGVVKLCDFGFARMISPGESYTDYVA----TRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
D V+K+ DFG AR++ S+ Y++ T+WYR+P LL+ Y+ +D+WA C+
Sbjct: 160 EDLVLKIGDFGLARIVDQHYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIL 219
Query: 629 AELLT 643
AE+LT
Sbjct: 220 AEMLT 224
Score = 33.9 bits (74), Expect = 0.51
Identities = 23/62 (37%), Positives = 31/62 (50%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPN 240
R+ LG G GLV + VAVKK + D K ALREI++++ L H N
Sbjct: 19 RFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALS--DARSMKHALREIKIIRRLDHDN 76
Query: 241 LV 246
+V
Sbjct: 77 IV 78
>BC117216-1|AAI17217.1| 587|Homo sapiens mitogen-activated protein
kinase 4 protein.
Length = 587
Score = 92.3 bits (219), Expect = 1e-18
Identities = 47/125 (37%), Positives = 75/125 (60%), Gaps = 5/125 (4%)
Frame = +2
Query: 284 HLVFEYCDHTVLHELEKYPAGCPELLSKQIIWQTLQGVAYCHRHNCIHRDVKPENILL-T 460
++V EY + + LE+ E +K ++Q L+G+ Y H N +HRD+KP NI + T
Sbjct: 102 YIVQEYMETDLARLLEQ--GTLAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFIST 159
Query: 461 SDGVVKLCDFGFARMISPGESYTDYVA----TRWYRAPELLVGDTMYSTPVDVWAIXCVF 628
D V+K+ DFG AR++ S+ Y++ T+WYR+P LL+ Y+ +D+WA C+
Sbjct: 160 EDLVLKIGDFGLARIVDQHYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCIL 219
Query: 629 AELLT 643
AE+LT
Sbjct: 220 AEMLT 224
Score = 33.9 bits (74), Expect = 0.51
Identities = 23/62 (37%), Positives = 31/62 (50%)
Frame = +1
Query: 61 RYEKLAKLGEGSYGLVYKCRNRDTGEIVAVKKFVENEDDPLIRKIALREIRMLKNLKHPN 240
R+ LG G GLV + VAVKK + D K ALREI++++ L H N
Sbjct: 19 RFVDFQPLGFGVNGLVLSAVDSRACRKVAVKKIALS--DARSMKHALREIKIIRRLDHDN 76
Query: 241 LV 246
+V
Sbjct: 77 IV 78
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 95,979,704
Number of Sequences: 237096
Number of extensions: 2107234
Number of successful extensions: 16276
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 12331
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 14812
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7310122300
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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