Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fprWP08_F_C01
(657 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9V6K3 Cluster: Tyrosine-protein kinase transmembrane r... 173 3e-42
UniRef50_Q17LF1 Cluster: Muscle-specific tyrosine kinase recepto... 169 5e-41
UniRef50_Q4R1V1 Cluster: Neurospecific receptor kinase; n=1; Dap... 145 9e-34
UniRef50_Q8AXY6 Cluster: Muscle, skeletal receptor tyrosine prot... 81 2e-14
UniRef50_O15146 Cluster: Muscle, skeletal receptor tyrosine prot... 76 9e-13
UniRef50_Q4TBR4 Cluster: Chromosome undetermined SCAF7099, whole... 66 7e-10
UniRef50_Q9Y1Y6 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 44 0.003
UniRef50_UPI0000E47617 Cluster: PREDICTED: similar to muscle spe... 44 0.004
UniRef50_Q01973 Cluster: Tyrosine-protein kinase transmembrane r... 43 0.007
UniRef50_A1IKE0 Cluster: Receptor tyrosine kinase-like orphan re... 42 0.017
UniRef50_A7RX97 Cluster: Predicted protein; n=1; Nematostella ve... 36 1.1
UniRef50_Q9BKL8 Cluster: Tyrosine-protein kinase receptor; n=2; ... 35 1.5
>UniRef50_Q9V6K3 Cluster: Tyrosine-protein kinase transmembrane
receptor Ror2 precursor; n=2; Sophophora|Rep:
Tyrosine-protein kinase transmembrane receptor Ror2
precursor - Drosophila melanogaster (Fruit fly)
Length = 724
Score = 173 bits (421), Expect = 3e-42
Identities = 73/136 (53%), Positives = 97/136 (71%), Gaps = 3/136 (2%)
Frame = +3
Query: 258 YCGPYNGQVCKSYSTGYVWYN---HTGGLDNEKITSGLWKEMISNLQEPCRTQAERLLCA 428
YC PY+G+VCK Y TG VWY+ TGG NE++T+ LW E+IS+L CR AE++LCA
Sbjct: 69 YCAPYSGKVCKEYLTGQVWYSLEDPTGGWKNEQVTTALWDELISDLTGLCREAAEKMLCA 128
Query: 429 YAFPKCINKDGVGYFALPLCYEDCMAVKMQFCYNDWIVIEDQKERGVFFESXGHFRLPEC 608
YAFP C + G A PLC+EDC A +QFCYNDW++IE++KER +F +S GHFRLP C
Sbjct: 129 YAFPNCHMEGGRAVKA-PLCFEDCQATHLQFCYNDWVLIEEKKERNMFIKSRGHFRLPNC 187
Query: 609 ENLPHYSGKGSQVSCN 656
+LPHY+ + +C+
Sbjct: 188 SSLPHYNASMRRPNCS 203
>UniRef50_Q17LF1 Cluster: Muscle-specific tyrosine kinase receptor;
n=5; Endopterygota|Rep: Muscle-specific tyrosine kinase
receptor - Aedes aegypti (Yellowfever mosquito)
Length = 666
Score = 169 bits (411), Expect = 5e-41
Identities = 73/136 (53%), Positives = 101/136 (74%), Gaps = 3/136 (2%)
Frame = +3
Query: 258 YCGPYNGQVCKSYSTG-YVWYNH--TGGLDNEKITSGLWKEMISNLQEPCRTQAERLLCA 428
YC PYNG+VCK++ G VWYN +GG NE+IT+ L++++I++L + CR AE+LLCA
Sbjct: 48 YCAPYNGKVCKTFVKGRQVWYNRDGSGGWLNEQITTALFRDLITDLPDYCRPAAEKLLCA 107
Query: 429 YAFPKCINKDGVGYFALPLCYEDCMAVKMQFCYNDWIVIEDQKERGVFFESXGHFRLPEC 608
+AFP+C+ +DGV LPLCYEDC+A +QFCYNDW +IE++KERG +S GHFRLP C
Sbjct: 108 FAFPQCVIRDGVTV-RLPLCYEDCVATHLQFCYNDWALIEEKKERGDVIKSRGHFRLPNC 166
Query: 609 ENLPHYSGKGSQVSCN 656
E+LP Y+ +C+
Sbjct: 167 EDLPRYNKTARHSTCS 182
>UniRef50_Q4R1V1 Cluster: Neurospecific receptor kinase; n=1;
Daphnia magna|Rep: Neurospecific receptor kinase -
Daphnia magna
Length = 685
Score = 145 bits (351), Expect = 9e-34
Identities = 63/134 (47%), Positives = 88/134 (65%), Gaps = 8/134 (5%)
Frame = +3
Query: 258 YCGPYNGQVCKSY--STGYVWYN-----HTGGLDNEKITSGLWKEMISNLQEPCRTQAER 416
YCG Y G +C+ + VWYN TGG NE++ GLW+E+++ L+EPC++ A++
Sbjct: 357 YCGRYTGNICRGQLSNPASVWYNISSNDQTGGWLNEQLVHGLWEEVVNTLREPCKSAAKK 416
Query: 417 LLCAYAFPKC-INKDGVGYFALPLCYEDCMAVKMQFCYNDWIVIEDQKERGVFFESXGHF 593
LLC YAFP+C +++DG LPLCYEDCMA + FC +DW +E K+RG + S GHF
Sbjct: 417 LLCLYAFPECHLDEDGFAR-KLPLCYEDCMATRQLFCVDDWAQLESNKQRGFYLGSRGHF 475
Query: 594 RLPECENLPHYSGK 635
RLP+CE LP +
Sbjct: 476 RLPKCEKLPRIGSR 489
>UniRef50_Q8AXY6 Cluster: Muscle, skeletal receptor tyrosine protein
kinase precursor; n=18; Gnathostomata|Rep: Muscle,
skeletal receptor tyrosine protein kinase precursor -
Gallus gallus (Chicken)
Length = 947
Score = 81.4 bits (192), Expect = 2e-14
Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 5/126 (3%)
Frame = +3
Query: 258 YCGPYNGQVCKSYST--GYVWYNHTGGLDNEK---ITSGLWKEMISNLQEPCRTQAERLL 422
YC Y G+VC + + V++N + E + W E+ + C+ AE LL
Sbjct: 316 YCSTYRGEVCSAILSRNALVFFNSSYADPEETQELLVHTAWTEL-KTVSSFCQPAAESLL 374
Query: 423 CAYAFPKCINKDGVGYFALPLCYEDCMAVKMQFCYNDWIVIEDQKERGVFFESXGHFRLP 602
C Y F +C GVG P+C E+C+AVK +C+ +W+ +E+ +RG++ LP
Sbjct: 375 CNYIFQEC-KPSGVGPAPKPICRENCLAVKDLYCFKEWLSMEENSQRGIYKPGLMLLALP 433
Query: 603 ECENLP 620
EC LP
Sbjct: 434 ECNRLP 439
>UniRef50_O15146 Cluster: Muscle, skeletal receptor tyrosine protein
kinase precursor; n=53; Euteleostomi|Rep: Muscle,
skeletal receptor tyrosine protein kinase precursor -
Homo sapiens (Human)
Length = 869
Score = 75.8 bits (178), Expect = 9e-13
Identities = 42/126 (33%), Positives = 64/126 (50%), Gaps = 5/126 (3%)
Frame = +3
Query: 258 YCGPYNGQVCKSY-STGYVWYNHTGGLDNEKITSGL----WKEMISNLQEPCRTQAERLL 422
YC Y G+VC + + + + +T D E+ L W E+ + CR AE LL
Sbjct: 316 YCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNEL-KVVSPVCRPAAEALL 374
Query: 423 CAYAFPKCINKDGVGYFALPLCYEDCMAVKMQFCYNDWIVIEDQKERGVFFESXGHFRLP 602
C + F +C GV +P+C E C+AVK FC +W+V+E++ RG++ +P
Sbjct: 375 CNHIFQEC--SPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVP 432
Query: 603 ECENLP 620
EC LP
Sbjct: 433 ECSKLP 438
>UniRef50_Q4TBR4 Cluster: Chromosome undetermined SCAF7099, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF7099, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1000
Score = 66.1 bits (154), Expect = 7e-10
Identities = 44/132 (33%), Positives = 60/132 (45%), Gaps = 11/132 (8%)
Frame = +3
Query: 258 YCGPYNGQVCKSY--STGYVWYNHT--GGLD-NEKITSGLWKEMISNLQEPCRTQAERLL 422
YC Y G VC++ V++N + D E + LW + L C LL
Sbjct: 353 YCSGYRGDVCRAILQDDQLVFFNSSLPDPEDLQEYLVQSLWPAL-EGLGAACGPAMHSLL 411
Query: 423 CAYAFPKCINKDGVGYFALPLCYEDCMAVKMQFCYNDWIVIED--QKERGVFFESXGHFR 596
C AFP C N G G P+C E C+AVK +C +W V+E + G+F + G R
Sbjct: 412 CHSAFPDC-NPSGFGPAPKPVCREHCLAVKELYCQREWAVLEGSASAQSGLFRSATGSSR 470
Query: 597 ----LPECENLP 620
LP C+ LP
Sbjct: 471 PSSLLPNCQALP 482
>UniRef50_Q9Y1Y6 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 948
Score = 44.0 bits (99), Expect = 0.003
Identities = 35/127 (27%), Positives = 53/127 (41%), Gaps = 4/127 (3%)
Frame = +3
Query: 285 CKSYSTGYVWY-NHTGGLDNEKITSGLWKEMISNL---QEPCRTQAERLLCAYAFPKCIN 452
C S +G+V NHT G N+ S I + +PC + LLC YAFP C
Sbjct: 61 CHSTLSGHVVVVNHTRG--NQVQASAFIDRFIVGVLSAPKPCLERVLPLLCFYAFPTCDP 118
Query: 453 KDGVGYFALPLCYEDCMAVKMQFCYNDWIVIEDQKERGVFFESXGHFRLPECENLPHYSG 632
+ + P+C DC ++ +C + W GV G P+C+ + +S
Sbjct: 119 AYDIPVYQ-PICKWDCKIIRDFYCASIWSSFVSYLTAGVL--DLGVLDPPQCDTI-RFSD 174
Query: 633 KGSQVSC 653
G+ C
Sbjct: 175 AGTAPMC 181
>UniRef50_UPI0000E47617 Cluster: PREDICTED: similar to muscle
specific tyrosine kinase receptor; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
muscle specific tyrosine kinase receptor -
Strongylocentrotus purpuratus
Length = 827
Score = 43.6 bits (98), Expect = 0.004
Identities = 37/128 (28%), Positives = 55/128 (42%), Gaps = 7/128 (5%)
Frame = +3
Query: 258 YCGPYNGQVCKSY---STGYVWYNHTG----GLDNEKITSGLWKEMISNLQEPCRTQAER 416
YC YNG C + S Y++ N G LDN K++ L + ++++ E C+
Sbjct: 284 YCAAYNGATCHNQLPSSPYYIFVNGHGDEPLALDN-KLSEILSSKTMTSMPEDCQAGIRE 342
Query: 417 LLCAYAFPKCINKDGVGYFALPLCYEDCMAVKMQFCYNDWIVIEDQKERGVFFESXGHFR 596
LLC PKC G +C EDC V+ C +W + + + +
Sbjct: 343 LLCHATHPKC-QVVGQKPRGQKICKEDCEIVQ-SMC-PEWAQLVN-RFLDPLPDKIRSLG 398
Query: 597 LPECENLP 620
L CENLP
Sbjct: 399 LSSCENLP 406
>UniRef50_Q01973 Cluster: Tyrosine-protein kinase transmembrane
receptor ROR1 precursor; n=21; Euteleostomi|Rep:
Tyrosine-protein kinase transmembrane receptor ROR1
precursor - Homo sapiens (Human)
Length = 937
Score = 42.7 bits (96), Expect = 0.007
Identities = 34/125 (27%), Positives = 49/125 (39%), Gaps = 4/125 (3%)
Frame = +3
Query: 258 YCGPYNGQVCKSY---STGYVWYNHTGGLDNEKITSGLWK-EMISNLQEPCRTQAERLLC 425
+C PY G C + T Y+ H G +IT+ S+L + C A LC
Sbjct: 169 FCQPYRGIACARFIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLC 228
Query: 426 AYAFPKCINKDGVGYFALPLCYEDCMAVKMQFCYNDWIVIEDQKERGVFFESXGHFRLPE 605
YAFP C V LC ++C ++ C ++I +LP
Sbjct: 229 HYAFPYCDETSSVPK-PRDLCRDECEILENVLCQTEYIFARSNP------MILMRLKLPN 281
Query: 606 CENLP 620
CE+LP
Sbjct: 282 CEDLP 286
>UniRef50_A1IKE0 Cluster: Receptor tyrosine kinase-like orphan
receptor; n=2; Nematostella vectensis|Rep: Receptor
tyrosine kinase-like orphan receptor - Nematostella
vectensis
Length = 715
Score = 41.5 bits (93), Expect = 0.017
Identities = 36/126 (28%), Positives = 50/126 (39%), Gaps = 5/126 (3%)
Frame = +3
Query: 258 YCGPYNGQVC-KSY----STGYVWYNHTGGLDNEKITSGLWKEMISNLQEPCRTQAERLL 422
YC Y G +C KS S N G ++ + + L + C+ LL
Sbjct: 143 YCVRYTGHICSKSINHKKSVFISAVNQQGSIEKKLEIAFNTISRSKKLSDSCQPYVLPLL 202
Query: 423 CAYAFPKCINKDGVGYFALPLCYEDCMAVKMQFCYNDWIVIEDQKERGVFFESXGHFRLP 602
C Y FP C + PLCY++C ++ C E+ KE V ES P
Sbjct: 203 CHYLFPYCDDAASQPQ-PRPLCYDECDLLRKDVC------SEEYKE--VQKESLSVVSFP 253
Query: 603 ECENLP 620
+CE LP
Sbjct: 254 DCERLP 259
>UniRef50_A7RX97 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 508
Score = 35.5 bits (78), Expect = 1.1
Identities = 22/88 (25%), Positives = 33/88 (37%)
Frame = +3
Query: 261 CGPYNGQVCKSYSTGYVWYNHTGGLDNEKITSGLWKEMISNLQEPCRTQAERLLCAYAFP 440
C PY G C Y G Y + E + L + ++ + C+ LC Y P
Sbjct: 1 CEPYKGTFCSKYLKGKNVYVKDRQQNVENKVATLIGILNRHVTDRCKEYVIPTLCNYIIP 60
Query: 441 KCINKDGVGYFALPLCYEDCMAVKMQFC 524
C KD + C +DC ++ C
Sbjct: 61 PCA-KDSKKPRPIRFCRDDCEVLQNTVC 87
>UniRef50_Q9BKL8 Cluster: Tyrosine-protein kinase receptor; n=2;
Eumetazoa|Rep: Tyrosine-protein kinase receptor -
Aplysia californica (California sea hare)
Length = 1145
Score = 35.1 bits (77), Expect = 1.5
Identities = 22/99 (22%), Positives = 43/99 (43%), Gaps = 4/99 (4%)
Frame = +3
Query: 258 YCGPYNGQVCKSYSTG---YVWYNHTGGLDNEKITSGLWK-EMISNLQEPCRTQAERLLC 425
+C Y G C + YV T EK + + S++ + C+ + LC
Sbjct: 234 FCQIYRGSTCAKFVGNMSIYVTSKLTQSRAEEKYMAAFAVIQASSHMSQRCQQYGIQSLC 293
Query: 426 AYAFPKCINKDGVGYFALPLCYEDCMAVKMQFCYNDWIV 542
+AFP C +K +C ++C+A++ C ++++
Sbjct: 294 YHAFPLC-DKTADRPTPRKICRDECLALENDICRTEYLM 331
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 638,471,831
Number of Sequences: 1657284
Number of extensions: 12373131
Number of successful extensions: 28192
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 27358
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 28170
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 49586781480
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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