Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fprWP07_F_P24
(655 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9NR45 Cluster: Sialic acid synthase; n=39; Coelomata|R... 219 6e-56
UniRef50_Q9VG74 Cluster: CG5232-PA; n=4; Diptera|Rep: CG5232-PA ... 177 3e-43
UniRef50_UPI0000D9DE3E Cluster: PREDICTED: similar to N-acetylne... 139 5e-32
UniRef50_Q07IS3 Cluster: N-acetylneuraminate synthase; n=1; Rhod... 135 8e-31
UniRef50_A6D0F9 Cluster: Sialic acid synthase; n=2; Gammaproteob... 117 2e-25
UniRef50_Q9RDX5 Cluster: N-acetylneuraminic acid condensing enzy... 117 3e-25
UniRef50_A0NMM3 Cluster: N-acylneuraminate-9-phosphate synthase;... 114 2e-24
UniRef50_Q1IMQ8 Cluster: N-acetylneuraminate synthase; n=16; Bac... 113 3e-24
UniRef50_A4FX91 Cluster: N-acylneuraminate-9-phosphate synthase;... 111 1e-23
UniRef50_A6L7H8 Cluster: Sialic acid synthase; n=1; Bacteroides ... 110 3e-23
UniRef50_A7DQW3 Cluster: N-acylneuraminate-9-phosphate synthase;... 109 4e-23
UniRef50_Q74B32 Cluster: Polysaccharide biosynthesis protein, pu... 107 2e-22
UniRef50_Q58465 Cluster: Uncharacterized protein MJ1065; n=1; Me... 107 2e-22
UniRef50_Q8A711 Cluster: Sialic acid synthase; n=1; Bacteroides ... 105 9e-22
UniRef50_Q04TT0 Cluster: N-acetyl neuraminic (Sialic) acid synth... 104 2e-21
UniRef50_UPI00015B984F Cluster: UPI00015B984F related cluster; n... 102 7e-21
UniRef50_Q0M1E8 Cluster: N-acylneuraminate-9-phosphate synthase;... 101 2e-20
UniRef50_Q0FYM0 Cluster: N-acylneuraminate-9-phosphate synthase;... 100 3e-20
UniRef50_Q3AZQ1 Cluster: N-acylneuraminate-9-phosphate synthase;... 99 1e-19
UniRef50_A5MZ25 Cluster: Predicted polysaccharide biosynthesis p... 97 3e-19
UniRef50_Q0IDR1 Cluster: N-acetylneuraminic acid condensing enzy... 96 7e-19
UniRef50_Q04TM5 Cluster: N-acetylneuraminic acid (Sialic acid) s... 95 1e-18
UniRef50_Q0A628 Cluster: N-acylneuraminate-9-phosphate synthase;... 95 1e-18
UniRef50_A4AP54 Cluster: N-acetylneuraminate synthase; n=3; cell... 92 9e-18
UniRef50_Q893U6 Cluster: N-acetylneuraminate synthase; n=1; Clos... 92 1e-17
UniRef50_Q2Y4J1 Cluster: NeuB family member; n=5; cellular organ... 91 2e-17
UniRef50_A3V3D1 Cluster: Polysialic acid capsule biosynthesis pr... 90 5e-17
UniRef50_Q9A4G6 Cluster: NeuB protein, putative; n=17; Bacteria|... 87 3e-16
UniRef50_Q73P39 Cluster: NeuB family protein; n=1; Treponema den... 87 3e-16
UniRef50_A4B2T9 Cluster: NeuB:Antifreeze-like protein; n=1; Alte... 86 8e-16
UniRef50_Q3XXA4 Cluster: N-acetylneuraminate synthase; n=1; Ente... 85 2e-15
UniRef50_A7GGU3 Cluster: NeuB family protein; n=1; Clostridium b... 85 2e-15
UniRef50_Q8TJL5 Cluster: N-acetylneuraminic acid phosphate synth... 84 3e-15
UniRef50_Q8DDZ7 Cluster: Sialic acid synthase; n=5; Bacteria|Rep... 83 4e-15
UniRef50_Q4VKA5 Cluster: NeuNAc condensing enzyme; n=54; cellula... 83 6e-15
UniRef50_Q12JI6 Cluster: N-acetylneuraminic acid synthase-like p... 83 6e-15
UniRef50_A2C5V5 Cluster: Sialic acid synthase; n=1; Prochlorococ... 82 1e-14
UniRef50_Q89HL9 Cluster: Blr5971 protein; n=1; Bradyrhizobium ja... 81 2e-14
UniRef50_Q5R082 Cluster: Sialic acid synthase; n=47; Bacteria|Re... 79 7e-14
UniRef50_Q2N2P7 Cluster: NeuB; n=7; Proteobacteria|Rep: NeuB - A... 79 7e-14
UniRef50_Q97H26 Cluster: Sialic acid synthase; n=14; cellular or... 79 9e-14
UniRef50_A3PE56 Cluster: Sialic acid synthase; n=1; Prochlorococ... 79 9e-14
UniRef50_P39625 Cluster: Spore coat polysaccharide biosynthesis ... 79 9e-14
UniRef50_Q1GST3 Cluster: N-acylneuraminate-9-phosphate synthase;... 79 1e-13
UniRef50_Q46675 Cluster: NeuB protein; n=8; Bacteria|Rep: NeuB p... 78 2e-13
UniRef50_Q1PVV9 Cluster: Similarity to N-acetyl neuramic acid sy... 78 2e-13
UniRef50_Q30V22 Cluster: N-acylneuraminate-9-phosphate synthase;... 77 4e-13
UniRef50_Q93NQ2 Cluster: NnaB; n=7; Bacteria|Rep: NnaB - Escheri... 77 4e-13
UniRef50_Q04TP3 Cluster: N-acetylneuraminic acid (Sialic acid) s... 77 4e-13
UniRef50_Q18EL3 Cluster: Sialic acid synthase; n=1; Haloquadratu... 77 5e-13
UniRef50_A1RHT0 Cluster: N-acylneuraminate-9-phosphate synthase;... 74 3e-12
UniRef50_Q89HJ8 Cluster: Blr5992 protein; n=2; Proteobacteria|Re... 73 6e-12
UniRef50_Q5QWT8 Cluster: Sialic acid synthase; n=14; Bacteria|Re... 73 6e-12
UniRef50_A4MIF1 Cluster: N-acylneuraminate-9-phosphate synthase;... 73 6e-12
UniRef50_Q7VHQ5 Cluster: Sialic acid synthase; n=6; Helicobacter... 73 8e-12
UniRef50_A3Y8V9 Cluster: NeuB family protein; n=1; Marinomonas s... 72 1e-11
UniRef50_UPI0000384B44 Cluster: COG2089: Sialic acid synthase; n... 72 1e-11
UniRef50_A1WSD6 Cluster: N-acylneuraminate-9-phosphate synthase;... 72 1e-11
UniRef50_Q7NQV6 Cluster: N-acetylneuraminic acid synthase; n=7; ... 71 3e-11
UniRef50_A0LYV7 Cluster: N-acetylneuraminate synthase; n=1; Gram... 71 3e-11
UniRef50_Q7MPQ0 Cluster: Sialic acid synthase; n=3; Proteobacter... 69 7e-11
UniRef50_Q726U8 Cluster: NeuB family protein; n=2; Desulfovibrio... 68 2e-10
UniRef50_A2BSE7 Cluster: Sialic acid synthase; n=1; Prochlorococ... 66 9e-10
UniRef50_A4U183 Cluster: N-acetylneuraminate synthase; n=1; Magn... 64 2e-09
UniRef50_Q11RF6 Cluster: N-acetylneuraminic acid synthetase; n=2... 64 3e-09
UniRef50_A4U173 Cluster: NeuB; n=1; Magnetospirillum gryphiswald... 64 3e-09
UniRef50_A6W187 Cluster: N-acylneuraminate-9-phosphate synthase;... 63 6e-09
UniRef50_Q0YTS4 Cluster: N-acylneuraminate-9-phosphate synthase;... 62 1e-08
UniRef50_Q0P8U0 Cluster: Pse synthetase; n=14; Campylobacter|Rep... 62 1e-08
UniRef50_Q2BI17 Cluster: N-acetylneuraminate synthase; n=4; Bact... 59 1e-07
UniRef50_A4BEM9 Cluster: Sialic acid synthase; n=1; Reinekea sp.... 58 1e-07
UniRef50_Q2IZW6 Cluster: N-acetylneuraminate synthase; n=1; Rhod... 58 2e-07
UniRef50_Q0AN71 Cluster: N-acetylneuraminate synthase; n=1; Mari... 57 3e-07
UniRef50_O83573 Cluster: Spore coat polysaccharide biosynthesis ... 56 6e-07
UniRef50_Q3B0R9 Cluster: N-acylneuraminate-9-phosphate synthase;... 56 7e-07
UniRef50_A0LAB4 Cluster: N-acetylneuraminic acid synthase, N-ter... 54 4e-06
UniRef50_Q2BJD7 Cluster: N-acetylneuraminic acid synthetase; n=1... 52 2e-05
UniRef50_Q8EC83 Cluster: Polysaccharide biosynthesis related-pro... 51 2e-05
UniRef50_A7DQU2 Cluster: N-acylneuraminate-9-phosphate synthase;... 51 2e-05
UniRef50_A5W0I0 Cluster: N-acetylneuraminic acid synthase, N-ter... 49 9e-05
UniRef50_Q319P5 Cluster: Putative spore coat polysaccharide bios... 45 0.002
UniRef50_Q0IDQ4 Cluster: NeuB family protein; n=1; Synechococcus... 45 0.002
UniRef50_UPI0000F219ED Cluster: PREDICTED: hypothetical protein;... 38 0.28
UniRef50_A5IGD9 Cluster: Spore coat polysaccharide biosynthesis ... 37 0.37
UniRef50_Q7NR94 Cluster: Probable spore coat polysaccharide bios... 36 0.85
UniRef50_Q8RI47 Cluster: Tetratricopeptide repeat family protein... 34 2.6
UniRef50_Q5A950 Cluster: Sterol 3-beta-glucosyltransferase; n=2;... 34 3.4
UniRef50_Q54FM7 Cluster: Putative uncharacterized protein; n=1; ... 33 6.0
UniRef50_Q8IFK4 Cluster: Hemoglobin A1 chain; n=2; Vestimentifer... 33 7.9
>UniRef50_Q9NR45 Cluster: Sialic acid synthase; n=39; Coelomata|Rep:
Sialic acid synthase - Homo sapiens (Human)
Length = 359
Score = 219 bits (534), Expect = 6e-56
Identities = 103/198 (52%), Positives = 130/198 (65%)
Frame = +1
Query: 58 VEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKF 237
+E+++ +GG +PCFIIAE GQNHQGD GA C KFQK+ L KF
Sbjct: 3 LELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEFKF 62
Query: 238 TKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFL 417
+K LERPY + +SWGKTYGEHK HLEFS QYREL RYA+EVGI FTAS MD ++ +FL
Sbjct: 63 NRKALERPYTSKHSWGKTYGEHKRHLEFSHDQYRELQRYAEEVGIFFTASGMDEMAVEFL 122
Query: 418 VNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLL 597
L VPF K+GSGD+NN +L+ A K P++IS+GM +K +Y I+ + FC L
Sbjct: 123 HELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVYQIVKPLNPNFCFL 182
Query: 598 HCISAYPVPFEDCNLTVL 651
C SAYP+ ED NL V+
Sbjct: 183 QCTSAYPLQPEDVNLRVI 200
>UniRef50_Q9VG74 Cluster: CG5232-PA; n=4; Diptera|Rep: CG5232-PA -
Drosophila melanogaster (Fruit fly)
Length = 372
Score = 177 bits (430), Expect = 3e-43
Identities = 87/182 (47%), Positives = 116/182 (63%), Gaps = 1/182 (0%)
Frame = +1
Query: 109 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 288
+IIAE GQNHQG G CVKFQK+ L KFT+ L+R Y + ++WGK
Sbjct: 16 YIIAEIGQNHQGCVETAKKMIWEAKKAGCHCVKFQKSDLPAKFTRSALDREYISDHAWGK 75
Query: 289 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN 468
TYGEHK +LEFS QY +L + +E+ + FTASAMD S +FL L VPFIKIGSGD+NN
Sbjct: 76 TYGEHKEYLEFSKDQYLQLQAHCKELNVDFTASAMDERSLEFLSALNVPFIKIGSGDANN 135
Query: 469 LLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQ-FCLLHCISAYPVPFEDCNLT 645
LK AA+ +PL+ISTGM V+ I + K+ + L+HC+S+YP +DC+L
Sbjct: 136 FPLLKKAANLNLPLVISTGMQTMQTVERIVQTMRESGKEDYALMHCVSSYPTDPKDCSLQ 195
Query: 646 VL 651
++
Sbjct: 196 LI 197
>UniRef50_UPI0000D9DE3E Cluster: PREDICTED: similar to
N-acetylneuraminic acid phosphate synthase; n=1; Macaca
mulatta|Rep: PREDICTED: similar to N-acetylneuraminic
acid phosphate synthase - Macaca mulatta
Length = 274
Score = 139 bits (337), Expect = 5e-32
Identities = 65/113 (57%), Positives = 77/113 (68%)
Frame = +1
Query: 58 VEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKF 237
+E+++ +GG +PCFIIAE GQNHQGD GA C KFQK+ L KF
Sbjct: 3 LELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEFKF 62
Query: 238 TKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMD 396
+K LERPY + +SWGKTYGEHK HLEF+ QYREL RYA+EVGI FTAS MD
Sbjct: 63 NRKALERPYTSKHSWGKTYGEHKRHLEFNHDQYRELQRYAEEVGIFFTASGMD 115
>UniRef50_Q07IS3 Cluster: N-acetylneuraminate synthase; n=1;
Rhodopseudomonas palustris BisA53|Rep:
N-acetylneuraminate synthase - Rhodopseudomonas
palustris (strain BisA53)
Length = 357
Score = 135 bits (327), Expect = 8e-31
Identities = 70/185 (37%), Positives = 97/185 (52%)
Frame = +1
Query: 100 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNS 279
NP F+IAE G NHQGD GA VK QK FT + + YD+ N+
Sbjct: 16 NPSFVIAEVGHNHQGDIEKCKAIFKAAKEAGADAVKIQKRDNRALFTAEMYDSHYDSENA 75
Query: 280 WGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGD 459
+ TYG H+ LEF+ QY EL Y +++ ILF ++A D S + L + +P KI SGD
Sbjct: 76 YAHTYGTHRECLEFNREQYLELKEYCKQLDILFFSTAFDEPSAELLEEIDMPGFKIASGD 135
Query: 460 SNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCN 639
N LK AS P+I+STG + Y+ I ++ C++ C S YP P E+ N
Sbjct: 136 LVNTPLLKKVASYGKPIIVSTGGGTLADARLAYETIMPINRNLCIMQCTSGYPPPHEELN 195
Query: 640 LTVLQ 654
L V++
Sbjct: 196 LRVIE 200
>UniRef50_A6D0F9 Cluster: Sialic acid synthase; n=2;
Gammaproteobacteria|Rep: Sialic acid synthase - Vibrio
shilonii AK1
Length = 751
Score = 117 bits (282), Expect = 2e-25
Identities = 65/191 (34%), Positives = 92/191 (48%), Gaps = 1/191 (0%)
Frame = +1
Query: 85 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 264
+IG P FIIAE G NH G GA CVKFQ + + + +
Sbjct: 123 KIGDQEPSFIIAEIGNNHNGSLELAKELVDLAKAAGADCVKFQMRDMASMYNNEGDDD-- 180
Query: 265 DNPNSWGKTYG-EHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFI 441
D G Y + + D ++ E+F Y ++ IL + D S D L + V
Sbjct: 181 DASQDLGAQYVLDLLKRFQLCDEEFVEIFEYCKQKEILALCTPFDEASADKLEKIGVAGF 240
Query: 442 KIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPV 621
K+ S D N LKY A+KK+PLI+STGM + + + +++ + F LLHC S YP
Sbjct: 241 KVASADLTNHRLLKYLAAKKVPLILSTGMSVEQEIISAVELLEKESASFALLHCNSTYPA 300
Query: 622 PFEDCNLTVLQ 654
PF+D NLT L+
Sbjct: 301 PFKDVNLTYLK 311
>UniRef50_Q9RDX5 Cluster: N-acetylneuraminic acid condensing enzyme;
n=6; Bacteria|Rep: N-acetylneuraminic acid condensing
enzyme - Legionella pneumophila
Length = 338
Score = 117 bits (281), Expect = 3e-25
Identities = 73/190 (38%), Positives = 97/190 (51%), Gaps = 7/190 (3%)
Frame = +1
Query: 106 CFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERP-YDNPNS- 279
CFIIAEAG NH GD GA VKFQ T + K +E+ Y N+
Sbjct: 3 CFIIAEAGVNHNGDLQLAKELVYAAKESGADAVKFQ-TFKADTLVNKTVEKAEYQKNNAP 61
Query: 280 WGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGD 459
T E LE S+ + L A +GI F ++ D S DFL++L V +KI SG+
Sbjct: 62 ESSTQYEMLKALELSEEDHYLLSELANSLGIEFMSTGFDEQSIDFLISLGVKRLKIPSGE 121
Query: 460 SNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDII-----SSDHKQFCLLHCISAYPVP 624
N+ +L++ ASKK+PLIISTGM D V+ D + +S LLHC S YP
Sbjct: 122 ITNVPYLQHCASKKLPLIISTGMCDLQEVRVAIDTVKPYYGNSLSDYLVLLHCTSNYPAS 181
Query: 625 FEDCNLTVLQ 654
++D NL +Q
Sbjct: 182 YQDVNLKAMQ 191
>UniRef50_A0NMM3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Stappia aggregata IAM 12614|Rep:
N-acylneuraminate-9-phosphate synthase - Stappia
aggregata IAM 12614
Length = 287
Score = 114 bits (274), Expect = 2e-24
Identities = 65/179 (36%), Positives = 92/179 (51%), Gaps = 1/179 (0%)
Frame = +1
Query: 109 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 288
++IAE G NH GD G VKFQK + ++ + L RP +N +G
Sbjct: 8 YVIAEIGINHNGDIDQALEMIRKSKEAGCDAVKFQKRTVDVVYSAEELARPRENV--FGT 65
Query: 289 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN 468
T G+ K LEF Y + + +E+GI + AS D S DFL++ P+IK+ S +
Sbjct: 66 TNGDLKRGLEFGKADYDRIDKLCKELGIDWFASPWDEGSVDFLLDYDTPYIKVASAMVTD 125
Query: 469 LLFLKYAASKKIPLIISTGMVDKTAVKTIYDIIS-SDHKQFCLLHCISAYPVPFEDCNL 642
FL+Y A PL++STGM D VK+ D+I S + CL HC S YP ++ NL
Sbjct: 126 RDFLEYCARSGRPLLVSTGMSDMAMVKSFVDVIERSGGEIACLYHCTSTYPTRDDEINL 184
>UniRef50_Q1IMQ8 Cluster: N-acetylneuraminate synthase; n=16;
Bacteria|Rep: N-acetylneuraminate synthase -
Acidobacteria bacterium (strain Ellin345)
Length = 300
Score = 113 bits (272), Expect = 3e-24
Identities = 62/188 (32%), Positives = 94/188 (50%)
Frame = +1
Query: 88 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 267
+G + PC++IAE G NH GD G VKFQK + +T L +P +
Sbjct: 20 VGKDQPCYVIAEIGINHNGDMDIAKRLISVAVGAGCDAVKFQKRTIDVVYTAAELAKPRE 79
Query: 268 NPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 447
NP +G T G+ K LEF +++E+ RY +EV + + ASA D S DF+ VP KI
Sbjct: 80 NP--FGATNGDLKRGLEFGLEEFKEIDRYCREVRMPWFASAWDEASVDFIAQFDVPCFKI 137
Query: 448 GSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPF 627
S + L++ + P+++STGM + D++ D+ LL S YP +
Sbjct: 138 ASASLTDDNLLRHTRATGKPVMLSTGMSTVEQIDHAVDVLGKDN--LILLQACSTYPAYY 195
Query: 628 EDCNLTVL 651
E+ NL +
Sbjct: 196 EELNLKAI 203
>UniRef50_A4FX91 Cluster: N-acylneuraminate-9-phosphate synthase;
n=5; cellular organisms|Rep:
N-acylneuraminate-9-phosphate synthase - Methanococcus
maripaludis
Length = 348
Score = 111 bits (268), Expect = 1e-23
Identities = 67/189 (35%), Positives = 96/189 (50%), Gaps = 3/189 (1%)
Frame = +1
Query: 94 GNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNP 273
G FIIAEAG NH G G VKFQ T+ + Y
Sbjct: 11 GLKNAFIIAEAGVNHNGSLELAKKLIDVAFEAGVDAVKFQTFKTENVVTENAEKAEYQIQ 70
Query: 274 NSWGKTYGEHK--SHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 447
N+ ++ +++ LE S+ + L+ Y QE GILF ++ D S DFL +L VP KI
Sbjct: 71 NTGVESESQYEMIKKLELSEKDFERLYNYCQEKGILFLSTPFDFESADFLDDL-VPLFKI 129
Query: 448 GSGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQFCLLHCISAYPVP 624
S D NN+ FLK+ A KK P+IISTGM + + + + ++ + + LLHC+++YP
Sbjct: 130 SSTDLNNIPFLKHIAKKKKPVIISTGMGTLCEIEEAVTALKNAGNHEIMLLHCVTSYPAK 189
Query: 625 FEDCNLTVL 651
E NL V+
Sbjct: 190 DESLNLNVI 198
>UniRef50_A6L7H8 Cluster: Sialic acid synthase; n=1; Bacteroides
vulgatus ATCC 8482|Rep: Sialic acid synthase -
Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC
11154)
Length = 334
Score = 110 bits (264), Expect = 3e-23
Identities = 68/189 (35%), Positives = 93/189 (49%), Gaps = 4/189 (2%)
Frame = +1
Query: 100 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERP-YDNPN 276
N +IIAEAG NH G GA VKFQ T EK + E Y N
Sbjct: 3 NHVYIIAEAGVNHNGRLDLALQLCNAAKDAGADAVKFQ-TWKTEKIVTRNAELAVYQENN 61
Query: 277 SWGKTYGEHK--SHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIG 450
KT + K LE S + + + E+GI F ++ ++ S DFL N +PFIK+G
Sbjct: 62 ISDKTKSQFKMLKELELSYDNFEVVKNHCDEIGIQFLSTPDEIDSLDFLCNFNLPFIKLG 121
Query: 451 SGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIY-DIISSDHKQFCLLHCISAYPVPF 627
SGD N+ FL+ S+ I +++STGM V+ Y +I + K LLHC + YP P
Sbjct: 122 SGDVTNIPFLRLVGSRHIDVVLSTGMSYLGDVEIAYRTLIEAGAKSVSLLHCTTNYPCPM 181
Query: 628 EDCNLTVLQ 654
+ NL +Q
Sbjct: 182 HEVNLRAIQ 190
>UniRef50_A7DQW3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
N-acylneuraminate-9-phosphate synthase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 349
Score = 109 bits (263), Expect = 4e-23
Identities = 63/190 (33%), Positives = 90/190 (47%), Gaps = 1/190 (0%)
Frame = +1
Query: 85 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 264
RI P +IIAE G NH G+ GA+ VKFQK L + + + L+ P
Sbjct: 14 RISTKEPAYIIAEIGINHNGNITTAKKLIDVAVDAGANAVKFQKRSLNDIYREDVLKDP- 72
Query: 265 DNPNSWG-KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFI 441
N S G + + + +EF D Y+EL Y +E I F + D+ S +FL +P
Sbjct: 73 -NIESQGLEILLDVLNEVEFDDDAYKELTEYCKEKHITFLCTPWDIPSVEFLEKFDLPAY 131
Query: 442 KIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPV 621
KI S D N + PLI+STGM + ++ + + +F LLHC S YP
Sbjct: 132 KIASADMTNFPLISSLIQTGKPLIVSTGMSNMNEIEKTVSFMKEKNAKFALLHCNSTYPA 191
Query: 622 PFEDCNLTVL 651
P E NL ++
Sbjct: 192 PVETLNLELI 201
>UniRef50_Q74B32 Cluster: Polysaccharide biosynthesis protein,
putative; n=1; Geobacter sulfurreducens|Rep:
Polysaccharide biosynthesis protein, putative -
Geobacter sulfurreducens
Length = 350
Score = 107 bits (257), Expect = 2e-22
Identities = 63/192 (32%), Positives = 95/192 (49%), Gaps = 4/192 (2%)
Frame = +1
Query: 79 DIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLER 258
++ +G NP ++IAE G NH GD GA VKFQ ++ ER
Sbjct: 8 NVPVGAENPPYVIAEIGSNHNGDMNLCRQLIDAAAEAGAHAVKFQSWTENSLIAREEYER 67
Query: 259 --PY-DNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLK 429
Y D +G K++ + + Q+RE Y +E GI F ++ D L +L
Sbjct: 68 NTEYSDKKRHFGSLRDMVKTY-QLTTDQHREAHAYCRERGIAFCSTPFSPEEADLLESLD 126
Query: 430 VPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-HKQFCLLHCI 606
VPF KI S D +L FLKY A K+ P+++STGM ++ + + ++ + Q LLHC+
Sbjct: 127 VPFFKIASMDIVHLPFLKYVARKRRPMLLSTGMATLAEIEAAVETVRAEGNDQVVLLHCV 186
Query: 607 SAYPVPFEDCNL 642
S YP +E +L
Sbjct: 187 SIYPPDYEMIHL 198
>UniRef50_Q58465 Cluster: Uncharacterized protein MJ1065; n=1;
Methanocaldococcus jannaschii|Rep: Uncharacterized
protein MJ1065 - Methanococcus jannaschii
Length = 337
Score = 107 bits (257), Expect = 2e-22
Identities = 67/201 (33%), Positives = 98/201 (48%), Gaps = 1/201 (0%)
Frame = +1
Query: 55 MVEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEK 234
M ++KI D +G P FIIAE G NH GD GA +KFQ +
Sbjct: 1 MEKIKIGDRY-VGKGEPTFIIAEGGLNHNGDIDIGKELVKEAKKCGADAIKFQSYHTEDF 59
Query: 235 FTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDF 414
+KK Y E LE S+ ++ EL YA+++GI+F ++ +D+ D
Sbjct: 60 ISKK-------------SEYYELFKSLELSEEEFYELKEYAEKIGIMFISTPLDLKYVDI 106
Query: 415 LVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH-KQFC 591
L + VP KI SGD L+ A P+I+STGM D + ++ ++ +
Sbjct: 107 LNKMNVPAFKIASGDLTFYPLLEKVAKTGKPVILSTGMSDIGEIWEAVKVLENNGCRDII 166
Query: 592 LLHCISAYPVPFEDCNLTVLQ 654
LLHCIS+YP P+ED NL ++
Sbjct: 167 LLHCISSYPTPYEDVNLNAIK 187
>UniRef50_Q8A711 Cluster: Sialic acid synthase; n=1; Bacteroides
thetaiotaomicron|Rep: Sialic acid synthase - Bacteroides
thetaiotaomicron
Length = 346
Score = 105 bits (252), Expect = 9e-22
Identities = 59/192 (30%), Positives = 89/192 (46%), Gaps = 11/192 (5%)
Frame = +1
Query: 109 FIIAEAGQNHQGDXXXXXXXXXXXX-----------XXGASCVKFQKTCLGEKFTKKYLE 255
+II E GQNH G + VK K L E+ +
Sbjct: 5 YIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMNAVKMTKRDLSEELAVSQMN 64
Query: 256 RPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVP 435
+ YDNPNS+G+TYGEH++ LE D + E+++YA+ +G+ F + L
Sbjct: 65 QIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLDFIETLCAKGCLSLLKLFTPD 124
Query: 436 FIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAY 615
+K+ S D NL L+ A IP+I+STGM + + D+I+ H +LHC+S Y
Sbjct: 125 RLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDNALDVITRYHSNIAILHCVSQY 184
Query: 616 PVPFEDCNLTVL 651
P + NL +
Sbjct: 185 PTHPNNLNLRTI 196
>UniRef50_Q04TT0 Cluster: N-acetyl neuraminic (Sialic) acid
synthetase; n=4; Leptospira|Rep: N-acetyl neuraminic
(Sialic) acid synthetase - Leptospira borgpetersenii
serovar Hardjo-bovis (strain JB197)
Length = 332
Score = 104 bits (249), Expect = 2e-21
Identities = 61/196 (31%), Positives = 98/196 (50%), Gaps = 1/196 (0%)
Frame = +1
Query: 70 ITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKY 249
I ++ +G +P ++AE G NH D GA VKFQ T+++
Sbjct: 9 IASELYVGSESPPIVVAEIGLNHNNDEEIGKKTIAAAKKAGAQVVKFQSYV-----TEEF 63
Query: 250 LERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLK 429
++ NP++ K + E S+T +R+ + A++ G+ F ++ + + S L++LK
Sbjct: 64 ID--VHNPDA--KILVDIFKKYELSETMHRKFQKTAEDEGLFFFSTPLCVNSLHLLLSLK 119
Query: 430 VPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-HKQFCLLHCI 606
VP IKI SGD N L A K+P+I+S+G D V + + + CLLHC+
Sbjct: 120 VPAIKIASGDITNKTLLLETAKSKLPVILSSGAADFFEVNRAISFLEKEGTDKLCLLHCV 179
Query: 607 SAYPVPFEDCNLTVLQ 654
S YP P E NL V++
Sbjct: 180 SLYPTPPEKANLKVVE 195
>UniRef50_UPI00015B984F Cluster: UPI00015B984F related cluster; n=1;
unknown|Rep: UPI00015B984F UniRef100 entry - unknown
Length = 361
Score = 102 bits (245), Expect = 7e-21
Identities = 61/190 (32%), Positives = 89/190 (46%), Gaps = 2/190 (1%)
Frame = +1
Query: 88 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 267
IG + CF+IAEAG NH GD GA +KFQ + + Y
Sbjct: 23 IGNDGRCFVIAEAGVNHNGDVAMAHRLIDVAAAAGADAIKFQTFNAETLVDRSARKAAYQ 82
Query: 268 NPNSWGKTYG-EHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 444
N+ ++ E LE YR L +A + GI ++ D S DFL L VP K
Sbjct: 83 VTNTGSESSQFEMLRSLELPAQAYRALQDHAGQAGIALISTPFDEASVDFLATLGVPAYK 142
Query: 445 IGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVK-TIYDIISSDHKQFCLLHCISAYPV 621
+ SGD N L+ A+K P+IISTGM + ++ + + ++ ++ C L C S+YP
Sbjct: 143 VSSGDLTNHFLLEAVAAKGKPVIISTGMANLADIEGALACLRTAGAREVCALQCTSSYPA 202
Query: 622 PFEDCNLTVL 651
P + NL +
Sbjct: 203 PPDQINLRTI 212
>UniRef50_Q0M1E8 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Caulobacter sp. K31
Length = 310
Score = 101 bits (241), Expect = 2e-20
Identities = 58/181 (32%), Positives = 86/181 (47%)
Frame = +1
Query: 109 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 288
F+IAE G NH GD G VKFQK + +T + L +P +P WG
Sbjct: 34 FVIAEIGINHNGDLEITKQLIRAARDAGCDAVKFQKRTIDIVYTPEVLAQPRQSP--WGD 91
Query: 289 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN 468
T K LEF +Y + Y +E+G+ + ASA D+ S FL +P+ KI S +
Sbjct: 92 TQRAQKEGLEFGKAEYDVIDAYCRELGLAWFASAWDVPSQTFLAAYDLPYNKIASAMLTH 151
Query: 469 LLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNLTV 648
++ A++ + STGM + T +I+ + F L+H +S YP P D NL
Sbjct: 152 RPLIEAVAAEGKLVFASTGMCTFEQIDTAVEILRAAACPFVLMHTVSTYPTPPADLNLLT 211
Query: 649 L 651
+
Sbjct: 212 I 212
>UniRef50_Q0FYM0 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Fulvimarina pelagi HTCC2506|Rep:
N-acylneuraminate-9-phosphate synthase - Fulvimarina
pelagi HTCC2506
Length = 347
Score = 100 bits (239), Expect = 3e-20
Identities = 63/186 (33%), Positives = 87/186 (46%), Gaps = 2/186 (1%)
Frame = +1
Query: 100 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNS 279
N F++AEAG NH G GA +KFQ T + Y N
Sbjct: 13 NWVFVVAEAGVNHNGSIERALDMVEAAARAGADAIKFQTFRAAGLVTANAEKAAYQKRND 72
Query: 280 WGKT-YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 456
T E S LE S++Q+R + + VGI F ++ D S DFL +L V KI SG
Sbjct: 73 GIDTNQAEMLSALELSESQWRTIKDHCSMVGISFLSTPFDEDSADFLESLGVEAFKISSG 132
Query: 457 DSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDII-SSDHKQFCLLHCISAYPVPFED 633
D +L FL++ A K P+IISTGM + ++ D I ++ +LHC+S YP
Sbjct: 133 DLTHLAFLQHVARKGRPMIISTGMANLADIEEAVDAIEAAGSPPLAILHCVSDYPADPAS 192
Query: 634 CNLTVL 651
NL +
Sbjct: 193 SNLMAI 198
>UniRef50_Q3AZQ1 Cluster: N-acylneuraminate-9-phosphate synthase;
n=17; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Synechococcus sp. (strain CC9902)
Length = 762
Score = 98.7 bits (235), Expect = 1e-19
Identities = 59/191 (30%), Positives = 88/191 (46%), Gaps = 2/191 (1%)
Frame = +1
Query: 88 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 267
IG +PCF+IAE G NH GD GA C KFQ +G+ ++ + D
Sbjct: 128 IGAEHPCFVIAEIGNNHNGDINTALQLIDAAHAAGADCAKFQMRDMGQLYSNS--GKSSD 185
Query: 268 NPNSWGKTYG-EHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 444
+ G Y + + SD + F Y+ G++ + D S L + K
Sbjct: 186 MASDLGTQYTLDLLERFQLSDDELFHCFDYSASKGLVPLCTPWDQTSLQKLNQWGMEGFK 245
Query: 445 IGSGD-SNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPV 621
+ S D +N+ L + AA+ K PLI STGM + +++ + + LLHC S YP
Sbjct: 246 VASADFTNHALITQLAATGK-PLICSTGMASELEIRSGIRHLQKAGANYVLLHCNSTYPT 304
Query: 622 PFEDCNLTVLQ 654
PF+D NL L+
Sbjct: 305 PFKDVNLRYLE 315
>UniRef50_A5MZ25 Cluster: Predicted polysaccharide biosynthesis
protein; n=1; Clostridium kluyveri DSM 555|Rep:
Predicted polysaccharide biosynthesis protein -
Clostridium kluyveri DSM 555
Length = 335
Score = 97.1 bits (231), Expect = 3e-19
Identities = 64/201 (31%), Positives = 95/201 (47%), Gaps = 1/201 (0%)
Frame = +1
Query: 55 MVEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEK 234
M ++KI + I IG +PCFIIAEAG NH GD GA+ VKFQ +
Sbjct: 1 MNDIKIGNKI-IGNTHPCFIIAEAGSNHNGDIKQAKELVDIAVEAGANAVKFQTFTADKL 59
Query: 235 FTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDF 414
F+K + N K + EF ++E+ Y + GI+F + + D
Sbjct: 60 FSKNH------PANKIVKNF-------EFKLEWHKEMKEYCDKKGIMFITTPFQKDAVDL 106
Query: 415 LVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH-KQFC 591
L L + KI SGD + L Y ++ P+I+++GM VK ++ I + +
Sbjct: 107 LEKLNIEGYKIASGDMDYYPLLDYISNTGKPIILASGMAYMDEVKEAFNRIKNGKTEDIA 166
Query: 592 LLHCISAYPVPFEDCNLTVLQ 654
+LHC+S YP ED NL +Q
Sbjct: 167 ILHCVSNYPPKDEDINLKAIQ 187
>UniRef50_Q0IDR1 Cluster: N-acetylneuraminic acid condensing enzyme;
n=1; Synechococcus sp. CC9311|Rep: N-acetylneuraminic
acid condensing enzyme - Synechococcus sp. (strain
CC9311)
Length = 347
Score = 95.9 bits (228), Expect = 7e-19
Identities = 60/191 (31%), Positives = 85/191 (44%), Gaps = 2/191 (1%)
Frame = +1
Query: 85 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 264
RI +P +I+AE G NH G+ GA VKFQ E + Y
Sbjct: 11 RISSIDPTYIVAEIGVNHNGNISLAHKLIDSAKDAGADAVKFQTYVTDELVIRNTRTAKY 70
Query: 265 DNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 444
N+ E S + EL+R+ GI F ++ D VS F+ NLK IK
Sbjct: 71 QKENALFDDQYTMLEKYELSFESFHELYRHCAAAGIDFLSTPFDPVSLRFIANLKPVAIK 130
Query: 445 IGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIIS--SDHKQFCLLHCISAYP 618
SG+ N + L AA ++P+I+STGM + + + D I+ + +L C+S YP
Sbjct: 131 WASGELTNKMLLDQAAKTRLPIILSTGM---SRINDVDDAITWIGRNTPLVVLQCVSNYP 187
Query: 619 VPFEDCNLTVL 651
D NL VL
Sbjct: 188 AAMSDQNLRVL 198
>UniRef50_Q04TM5 Cluster: N-acetylneuraminic acid (Sialic acid)
synthetase; n=2; Leptospira borgpetersenii serovar
Hardjo-bovis|Rep: N-acetylneuraminic acid (Sialic acid)
synthetase - Leptospira borgpetersenii serovar
Hardjo-bovis (strain JB197)
Length = 282
Score = 95.5 bits (227), Expect = 1e-18
Identities = 61/192 (31%), Positives = 91/192 (47%)
Frame = +1
Query: 79 DIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLER 258
+I+IGGNNP FIIAEAG NH GD A+ +KFQ E+F +
Sbjct: 9 NIKIGGNNPVFIIAEAGLNHGGDLNLALRMIDEAADAKANAIKFQAYNSEERFGENKEAV 68
Query: 259 PYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPF 438
P +GK ++ L +Q+ ILF A+ D+ + + L + V
Sbjct: 69 NLVKPAEFGK-------------KEFLLLKERSQKKNILFFATPFDVPNLNMLKEIGVEI 115
Query: 439 IKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYP 618
+KI S D N+ L+ AA + +I+S G + ++T I F LLHC+S+YP
Sbjct: 116 LKIASCDICNITLLEAAADSGLIVILSRGTASASEIETAVSIFKKKKSPFILLHCVSSYP 175
Query: 619 VPFEDCNLTVLQ 654
+ D NL+ +Q
Sbjct: 176 MNEIDANLSAIQ 187
>UniRef50_Q0A628 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Alkalilimnicola ehrlichei MLHE-1|Rep:
N-acylneuraminate-9-phosphate synthase - Alkalilimnicola
ehrlichei (strain MLHE-1)
Length = 348
Score = 95.1 bits (226), Expect = 1e-18
Identities = 61/199 (30%), Positives = 91/199 (45%)
Frame = +1
Query: 55 MVEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEK 234
M E+ I D IG N+P ++IAEAG +H GA +KFQ E
Sbjct: 1 MTELHI-DGRAIGPNHPPYVIAEAGVHHYDSLELARAYVLEARKAGADAIKFQTYTADEL 59
Query: 235 FTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDF 414
T+ Y + + + S T+YR LF YA+E+GI ++ D S D
Sbjct: 60 VTR--WAPLYWTDARFETQHQVFSTKRGLSPTEYRSLFDYARELGITPLSTPFDPASVDL 117
Query: 415 LVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCL 594
L L + K+ S D + L+ A K P+++STG V++ +++ S+ L
Sbjct: 118 LDGLGMAAFKVASADITHRPLLQDIAGKGKPVLLSTGAASMAEVRSALEVLESEGVPVAL 177
Query: 595 LHCISAYPVPFEDCNLTVL 651
LHC AYP P + NL+ L
Sbjct: 178 LHCSLAYPTPVDQANLSRL 196
>UniRef50_A4AP54 Cluster: N-acetylneuraminate synthase; n=3;
cellular organisms|Rep: N-acetylneuraminate synthase -
Flavobacteriales bacterium HTCC2170
Length = 351
Score = 92.3 bits (219), Expect = 9e-18
Identities = 62/201 (30%), Positives = 87/201 (43%), Gaps = 2/201 (0%)
Frame = +1
Query: 55 MVEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEK 234
M +KI +D I +PCFIIAEAG NH G G CVKFQ
Sbjct: 1 MKSIKI-EDFLISKESPCFIIAEAGVNHNGKLEMALELVRKAKEIGVDCVKFQTFTAESV 59
Query: 235 FTKKYLERPYD-NPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFD 411
TKK + Y ++ E LE S Y ++ + I F ++ + D
Sbjct: 60 ITKKAPKANYQLEVTDPAESQFEMLKKLELSGDDYIKIIEECNKQNITFLSTPYNEEDAD 119
Query: 412 FLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQF 588
FL L V KI SG L FL++ A P+I+S+GM V + + I + + Q
Sbjct: 120 FLNKLGVSAFKIASGQIVELAFLEHVAKFGKPIILSSGMATLAEVYEAVMTIREAGNNQM 179
Query: 589 CLLHCISAYPVPFEDCNLTVL 651
+L C + YP ED N+ +
Sbjct: 180 AILQCTTNYPSQNEDANIRAM 200
>UniRef50_Q893U6 Cluster: N-acetylneuraminate synthase; n=1;
Clostridium tetani|Rep: N-acetylneuraminate synthase -
Clostridium tetani
Length = 351
Score = 91.9 bits (218), Expect = 1e-17
Identities = 57/198 (28%), Positives = 92/198 (46%), Gaps = 8/198 (4%)
Frame = +1
Query: 85 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 264
+IG N P +I+AE G NH GD G VKFQ +T K L
Sbjct: 11 KIGENYPAYIVAEIGANHNGDVNLAKRMIEVAAECGVDAVKFQT------YTAKELVSDT 64
Query: 265 DNPNSWG-------KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVN 423
D +WG +T G+ + ++E+F YA ++G++ ++ + +FL
Sbjct: 65 DRILTWGPCGKQKTETIGKMFDRIALPREAHKEVFEYANKLGLMAFSTPFSIKGVEFLNE 124
Query: 424 LKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVD-KTAVKTIYDIISSDHKQFCLLH 600
L+VP K+ + D + L LK K P+++S G A I +I S ++ ++H
Sbjct: 125 LEVPCFKVAASDVDYLDILKEIGKTKKPVMLSLGKCTLGEADLAIETLIESGCEKIVIMH 184
Query: 601 CISAYPVPFEDCNLTVLQ 654
C+S YP P + NL V++
Sbjct: 185 CVSQYPSPINEMNLKVIE 202
>UniRef50_Q2Y4J1 Cluster: NeuB family member; n=5; cellular
organisms|Rep: NeuB family member - uncultured archaeon
Length = 360
Score = 91.5 bits (217), Expect = 2e-17
Identities = 62/192 (32%), Positives = 93/192 (48%), Gaps = 10/192 (5%)
Frame = +1
Query: 109 FIIAEAGQNH-----QGDXX---XXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 264
FI+AEAG N+ +G+ GA +KFQ T E+ KY +
Sbjct: 19 FIVAEAGVNYYDIAKKGNIEPLEAAKLMIEKAADSGADAIKFQ-TYKAERIASKYSPAYW 77
Query: 265 DNPNSWGKT-YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFI 441
D K+ Y K +F + +Y+EL YA ILF ++ D + DFL L +P
Sbjct: 78 DVTKENTKSQYELFKKFDKFGEDEYKELAGYAANTDILFMSTPFDNEAVDFLDKL-MPVF 136
Query: 442 KIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-HKQFCLLHCISAYP 618
KI S D N+ F+ Y A K+ P+ +STG +K + I S+ + + +LHCI YP
Sbjct: 137 KISSSDITNIPFISYVARKRKPIFLSTGASTIEEIKEAVNAIESEGNDKIVILHCILNYP 196
Query: 619 VPFEDCNLTVLQ 654
+ED NL +++
Sbjct: 197 TKYEDANLGMIK 208
>UniRef50_A3V3D1 Cluster: Polysialic acid capsule biosynthesis
protein SiaC; n=3; Bacteria|Rep: Polysialic acid capsule
biosynthesis protein SiaC - Loktanella vestfoldensis
SKA53
Length = 343
Score = 89.8 bits (213), Expect = 5e-17
Identities = 55/186 (29%), Positives = 90/186 (48%)
Frame = +1
Query: 85 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 264
+IG +P +IAE G NH GD G VK Q + ++ T++ R
Sbjct: 7 KIGPEHPPLVIAEIGINHGGDLAVAKEMVRLAALSGCEMVKHQTHIIADEMTEE--ARQI 64
Query: 265 DNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 444
PN+ + E S + EL RY + +G+++ ++ + DFL +L VP K
Sbjct: 65 FPPNA-DVSIWEVMEACALSLDEEAELKRYTESLGMIWISTPFSRAAADFLQDLDVPAFK 123
Query: 445 IGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVP 624
IGSG+++NL +++ A P+I+STGM +++ I+ + LL C + YP P
Sbjct: 124 IGSGEADNLPLIRHIARMGKPVIMSTGMQSIESIRASVAILDGAGVDYALLECTNLYPSP 183
Query: 625 FEDCNL 642
E +L
Sbjct: 184 PEIVSL 189
>UniRef50_Q9A4G6 Cluster: NeuB protein, putative; n=17;
Bacteria|Rep: NeuB protein, putative - Caulobacter
crescentus (Caulobacter vibrioides)
Length = 356
Score = 87.4 bits (207), Expect = 3e-16
Identities = 60/192 (31%), Positives = 94/192 (48%), Gaps = 6/192 (3%)
Frame = +1
Query: 85 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 264
+IG ++ ++I E NH G G +K Q T + T ++RP
Sbjct: 18 KIGADHSPYVICELSGNHNGSLERCLAMVDAAADTGCDAIKIQ-TYTADTITLD-VDRPE 75
Query: 265 DNPNS--W-GKTYGE--HKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLK 429
+ W G+T E ++H F + +F A++ G+ +S D + D L +L
Sbjct: 76 FKIHGGLWDGRTLYELYEEAHTPFE--WHAAIFERARQRGVTIFSSPFDETAVDLLDSLG 133
Query: 430 VPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYD-IISSDHKQFCLLHCI 606
P KI S ++ +L +KYAA+K PLIISTGM + T ++T D +S+ LLHC+
Sbjct: 134 APAFKIASFEAVDLPLIKYAAAKGKPLIISTGMANLTEMQTALDTALSAGAPGVLLLHCV 193
Query: 607 SAYPVPFEDCNL 642
S+YP F D N+
Sbjct: 194 SSYPATFADANV 205
>UniRef50_Q73P39 Cluster: NeuB family protein; n=1; Treponema
denticola|Rep: NeuB family protein - Treponema denticola
Length = 379
Score = 87.0 bits (206), Expect = 3e-16
Identities = 61/187 (32%), Positives = 88/187 (47%), Gaps = 2/187 (1%)
Frame = +1
Query: 100 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNS 279
NP IAE G +H G GA VKFQ E D P
Sbjct: 19 NP-LTIAEIGTSHNGSIQKARNLIDVAAEAGAKAVKFQIVYADEILHPN--TGYVDLPTG 75
Query: 280 WGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGD 459
Y KS LE + Y+EL Y++ +LF+AS S + L LK FIKI S +
Sbjct: 76 KIPLYDRFKS-LELPVSFYKELAEYSRSKKLLFSASPFGFRSAEELAALKPDFIKIASPE 134
Query: 460 SNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQ--FCLLHCISAYPVPFED 633
N + LKY A IP+I+S+G+ ++ + S++K LLHCI++YP P ++
Sbjct: 135 LNYVQLLKYCAGFNIPMILSSGVSILKDIEKAVSFLRSENKDLPLALLHCITSYPAPEKE 194
Query: 634 CNLTVLQ 654
N++V++
Sbjct: 195 YNVSVIK 201
>UniRef50_A4B2T9 Cluster: NeuB:Antifreeze-like protein; n=1;
Alteromonas macleodii 'Deep ecotype'|Rep:
NeuB:Antifreeze-like protein - Alteromonas macleodii
'Deep ecotype'
Length = 347
Score = 85.8 bits (203), Expect = 8e-16
Identities = 56/192 (29%), Positives = 89/192 (46%), Gaps = 3/192 (1%)
Frame = +1
Query: 76 DDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLE 255
D I + +IIAE NH GD G S +K Q T + T L+
Sbjct: 4 DQTNINEAHKPYIIAELSANHGGDLSRAKESITKAAEVGVSAIKIQ-TYTPDTMTLDSLQ 62
Query: 256 RPYDNPNS-W-GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLK 429
+ + W G++ E + + ELF +A+ G+ ++ D + D L +L
Sbjct: 63 DDFIVKDGLWAGRSLYELYTEAYTPYEWHEELFNHAKNCGVTIFSTPFDETAVDLLESLN 122
Query: 430 VPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQFCLLHCI 606
P KI S + +L +KY ASK P+++STGM +T + + + + ++ + L HCI
Sbjct: 123 TPAYKIASFEIVDLPLVKYIASKNKPILMSTGMASQTEIEEAVTSVRANGDCELLLFHCI 182
Query: 607 SAYPVPFEDCNL 642
S+YP ED NL
Sbjct: 183 SSYPAVTEDSNL 194
>UniRef50_Q3XXA4 Cluster: N-acetylneuraminate synthase; n=1;
Enterococcus faecium DO|Rep: N-acetylneuraminate
synthase - Enterococcus faecium DO
Length = 335
Score = 84.6 bits (200), Expect = 2e-15
Identities = 58/182 (31%), Positives = 78/182 (42%), Gaps = 1/182 (0%)
Frame = +1
Query: 109 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPN-SWG 285
++IAE G NH G GA+ VKFQ + +KK Y N
Sbjct: 7 YVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKTNKLVSKKAPMAKYQKDNLKED 66
Query: 286 KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSN 465
+ E LE S + + + Y + I F ++ D S DFL + V KIGSGD
Sbjct: 67 SSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFDEESADFLKQIGVQGFKIGSGDLT 126
Query: 466 NLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNLT 645
NL FL+ +P+++STGM D V D +LHC S YP ED NL
Sbjct: 127 NLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFID--SPVTILHCTSNYPASSEDINLL 184
Query: 646 VL 651
+
Sbjct: 185 AI 186
>UniRef50_A7GGU3 Cluster: NeuB family protein; n=1; Clostridium
botulinum F str. Langeland|Rep: NeuB family protein -
Clostridium botulinum (strain Langeland / NCTC 10281 /
Type F)
Length = 343
Score = 84.6 bits (200), Expect = 2e-15
Identities = 60/191 (31%), Positives = 87/191 (45%), Gaps = 1/191 (0%)
Frame = +1
Query: 85 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY 264
++G + FIIAE G NH G+ GA VKFQ + +K Y
Sbjct: 10 KVGEKSSIFIIAEIGVNHNGNIDLAYKLIDLASKAGADAVKFQMF-----YPEKLCSEIY 64
Query: 265 DNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 444
K E S ++L Y +G+ F + D S D ++NL IK
Sbjct: 65 R------KDEIEMLKKYVLSFENMKKLRDYTYSLGLEFIVTPFDFKSLDDIINLDCSAIK 118
Query: 445 IGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQFCLLHCISAYPV 621
+ SG+ ++ F+K AAS PLIISTG + + V + + I S ++ +LHC+S YP
Sbjct: 119 VASGELTHIPFIKKAASYNKPLIISTGASNLSDVERAVIAIKSVADEKISILHCVSTYPS 178
Query: 622 PFEDCNLTVLQ 654
P E NL L+
Sbjct: 179 PDECLNLRALK 189
>UniRef50_Q8TJL5 Cluster: N-acetylneuraminic acid phosphate
synthase; n=11; cellular organisms|Rep:
N-acetylneuraminic acid phosphate synthase -
Methanosarcina acetivorans
Length = 286
Score = 83.8 bits (198), Expect = 3e-15
Identities = 56/180 (31%), Positives = 88/180 (48%), Gaps = 6/180 (3%)
Frame = +1
Query: 112 IIAEAGQNHQGDXXXXXXXXXXXXXX-GASCVKFQKTCLGEKFTKKYLERPYDNP-NSWG 285
+IAE G NH+G+ VKFQK E T + P+ P NS+G
Sbjct: 6 VIAEIGCNHKGEMEIAHEMIKVAAQFCKVDIVKFQKRTPVELLTPEEYNAPHPVPHNSYG 65
Query: 286 KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSN 465
KTYGEH+ LEF+ Q+++L ++ + G++++ S D+ + +V++ IKI S +
Sbjct: 66 KTYGEHREFLEFNLDQHKQLKKWCDDWGVVYSTSVWDLTAAKEIVSINPELIKIPSACNL 125
Query: 466 NLLFLKYAASKKIPLI-ISTGMV---DKTAVKTIYDIISSDHKQFCLLHCISAYPVPFED 633
L+Y + I +S GM ++ V T ++ K + C S YPVPFED
Sbjct: 126 KFDMLEYLCKEYDGEIHLSFGMTTNEEEEKVVTFFE-DRGRGKDLIIYSCTSGYPVPFED 184
>UniRef50_Q8DDZ7 Cluster: Sialic acid synthase; n=5; Bacteria|Rep:
Sialic acid synthase - Vibrio vulnificus
Length = 333
Score = 83.4 bits (197), Expect = 4e-15
Identities = 69/192 (35%), Positives = 89/192 (46%), Gaps = 7/192 (3%)
Frame = +1
Query: 100 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQ--KTCLGEKFTKKYLERPYDNP 273
N FIIAEAG NH GD G VKFQ KT L K E +N
Sbjct: 3 NKTFIIAEAGVNHNGDIRLAKQLIDAAADAGVDAVKFQTWKTELLVTEDAKMAEYQVENT 62
Query: 274 NSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGS 453
+T E LE S + EL Y + GI F ++ + S FL L+ F KIGS
Sbjct: 63 QR-EETQFEMLKRLELSYDDFTELKSYCDDKGITFMSTPDEEQSATFLDGLQAVF-KIGS 120
Query: 454 GDSNNLLFLKYAASKKIPLIISTGM----VDKTAVKTIYDI-ISSDHKQFCLLHCISAYP 618
G+ N FL++ AS P+I+STGM + AV T+ D +S D +LH + YP
Sbjct: 121 GELTNTPFLRHIASFAKPVILSTGMGYLSEVEHAVVTLRDAGLSLD--MITVLHATTDYP 178
Query: 619 VPFEDCNLTVLQ 654
ED NL ++
Sbjct: 179 TAPEDVNLLAMK 190
>UniRef50_Q4VKA5 Cluster: NeuNAc condensing enzyme; n=54; cellular
organisms|Rep: NeuNAc condensing enzyme - Escherichia
coli
Length = 350
Score = 83.0 bits (196), Expect = 6e-15
Identities = 62/190 (32%), Positives = 88/190 (46%), Gaps = 9/190 (4%)
Frame = +1
Query: 109 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWG- 285
+I+AE G NH GD G VKFQ T E+ KY + G
Sbjct: 9 YIVAEIGCNHNGDFELAKKMVKEAKSAGVDAVKFQ-TFKAEQLISKYAPKAEYQIKVTGN 67
Query: 286 -KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 462
+T E LE ++ +L YA+E+G+ ++ D S DFL + KI SG+
Sbjct: 68 EETQLEMTRKLELPYDEFIKLEEYAKELGLDVFSTPFDFDSIDFLASRNQKVWKIPSGEL 127
Query: 463 NNLLFLKYAASKKIP---LIISTGM--VDKT--AVKTIYDIISSDHKQFCLLHCISAYPV 621
NL +L+ A I +++STGM VD+ A+K D H+ +LHC + YP
Sbjct: 128 LNLPYLEKIAKLPIEDKKIVLSTGMATVDEINLALKVFIDN-GITHRNITILHCNTEYPT 186
Query: 622 PFEDCNLTVL 651
PFED NL +
Sbjct: 187 PFEDVNLNTI 196
>UniRef50_Q12JI6 Cluster: N-acetylneuraminic acid synthase-like
protein; n=1; Shewanella denitrificans OS217|Rep:
N-acetylneuraminic acid synthase-like protein -
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 /
DSM 15013)
Length = 359
Score = 83.0 bits (196), Expect = 6e-15
Identities = 55/200 (27%), Positives = 90/200 (45%), Gaps = 4/200 (2%)
Frame = +1
Query: 55 MVEVKITDDIR-IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGE 231
M + IT D R IG +IIAE NH+G G +K Q T
Sbjct: 1 MFKASITIDGRHIGPEYQPYIIAELSGNHKGSLSQALAMIDAAAASGVDAIKIQ-TYTAN 59
Query: 232 KFTKKYLERPYD-NPNSW-GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVS 405
T ++ + N W G+T + ++ LF +A++ + +S D+ +
Sbjct: 60 TITLQHDGPEFRINGGLWKGRTLFDLYEEAHTPWEWHKSLFEHAKKQNVTLFSSPFDLKA 119
Query: 406 FDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISS-DHK 582
+ L + + P KI S + N++ + AA P+++STG+ ++ + +++
Sbjct: 120 IELLESCECPAYKISSFEINDIGLIMAAAKTGKPIVMSTGLATLAEIEEAVEAVANAGGT 179
Query: 583 QFCLLHCISAYPVPFEDCNL 642
Q LLHCIS YP P EDCNL
Sbjct: 180 QLALLHCISGYPTPIEDCNL 199
>UniRef50_A2C5V5 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. MIT 9303|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain MIT 9303)
Length = 335
Score = 81.8 bits (193), Expect = 1e-14
Identities = 54/188 (28%), Positives = 86/188 (45%), Gaps = 7/188 (3%)
Frame = +1
Query: 112 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKT 291
IIAEAG NH G+ GA +KFQ E + + Y + T
Sbjct: 5 IIAEAGVNHNGEIQNAYRLIDSAKFAGADAIKFQSFSSIELTAENAPKAKYQQMYADRST 64
Query: 292 YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 471
E + LE ++ +++ + Y +++ I F ++A D L+ LKV IK+ SG+ +
Sbjct: 65 QREMLARLELNEMEHQLIADYCEKIEIEFLSTAFGQSQLDLLIKLKVQAIKVASGEITHW 124
Query: 472 LFLKYAASK----KIPLIISTGMVDKTAVKTIYDI-ISSDHK--QFCLLHCISAYPVPFE 630
LK A K + + +STGM + ++ DI I D + +LHC S YP P+
Sbjct: 125 PLLKEMAKKAYENNLDVYLSTGMSEIKEIQDALDIFIKEDISLGKIFILHCTSHYPAPYN 184
Query: 631 DCNLTVLQ 654
N+ L+
Sbjct: 185 AVNMKALR 192
>UniRef50_Q89HL9 Cluster: Blr5971 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr5971 protein - Bradyrhizobium
japonicum
Length = 641
Score = 81.4 bits (192), Expect = 2e-14
Identities = 52/185 (28%), Positives = 74/185 (40%)
Frame = +1
Query: 88 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 267
+G PC++IAE G NH GD GA C KFQ L E + L D
Sbjct: 19 LGDGEPCYVIAEVGNNHNGDFDRAIALVDAAVAAGADCAKFQMRKLDEVYRASSLSGK-D 77
Query: 268 NPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 447
+ + T + E + Q +++ Y GI + + D S L V K+
Sbjct: 78 DDLAVEYTL-DLLRRFELTTEQQKKIADYCASKGIQYLCTPWDAKSVAVLEGFGVQAYKV 136
Query: 448 GSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPF 627
S D NL L + LI+STGM +K + + + LLHC S YP
Sbjct: 137 ASADLTNLPLLARLIATGKTLIVSTGMSTTEEIKAAAEFLDERKAGYVLLHCQSTYPAAL 196
Query: 628 EDCNL 642
+ +L
Sbjct: 197 HNIHL 201
>UniRef50_Q5R082 Cluster: Sialic acid synthase; n=47; Bacteria|Rep:
Sialic acid synthase - Idiomarina loihiensis
Length = 352
Score = 79.4 bits (187), Expect = 7e-14
Identities = 48/179 (26%), Positives = 79/179 (44%)
Frame = +1
Query: 88 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 267
IG ++ ++AE G NH+G GA +K Q + ++ + +
Sbjct: 18 IGYDHDPVVVAEIGINHEGSLETAYEMVDAAVSAGAEIIKHQTHVVEDEMSA---DAKKV 74
Query: 268 NPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 447
P + + E ++ +L Y + G +F ++ + + L + V KI
Sbjct: 75 IPGNADVSIYEIMERCALNEEDETKLKEYVESKGAIFISTPFSRAAAERLERMGVEAYKI 134
Query: 448 GSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVP 624
GSG+ NN L+ AS K P+I+STGM D ++ DI Q+ LLHC + YP P
Sbjct: 135 GSGECNNYPLLELVASYKKPIILSTGMNDIPSIAKAVDIFRKHGVQYALLHCTNVYPTP 193
>UniRef50_Q2N2P7 Cluster: NeuB; n=7; Proteobacteria|Rep: NeuB -
Aeromonas hydrophila
Length = 345
Score = 79.4 bits (187), Expect = 7e-14
Identities = 58/194 (29%), Positives = 90/194 (46%), Gaps = 6/194 (3%)
Frame = +1
Query: 88 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 267
IG ++IAE NH G+ GAS VK Q T + T K +RP
Sbjct: 8 IGPAQAPYVIAELSANHNGNLERALAIMTAAKAAGASAVKLQ-TYRPDTITLKS-DRPEF 65
Query: 268 NPNSWGKTYGEHKSH--LEFSDTQY---RELFRYAQEVGILFTASAMDMVSFDFLVNLKV 432
+ G + H + E++ T + + LF +E+G+ +S D + D L +L
Sbjct: 66 QIH--GGLWDGHSLYDLYEWAHTPWEWHQALFAKGRELGLTVFSSPFDFSAVDLLESLDC 123
Query: 433 PFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDI-ISSDHKQFCLLHCIS 609
P KI S + +L ++YAA PLI+STGM ++ + ++ + Q LLHC+S
Sbjct: 124 PAYKIASFELVDLPLIRYAAQTGKPLIMSTGMANEAEIAAAVEMALKHGSGQLALLHCVS 183
Query: 610 AYPVPFEDCNLTVL 651
YP P + NL +
Sbjct: 184 GYPAPAAEYNLRTI 197
>UniRef50_Q97H26 Cluster: Sialic acid synthase; n=14; cellular
organisms|Rep: Sialic acid synthase - Clostridium
acetobutylicum
Length = 350
Score = 79.0 bits (186), Expect = 9e-14
Identities = 61/199 (30%), Positives = 96/199 (48%), Gaps = 10/199 (5%)
Frame = +1
Query: 85 RIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFT----KKYL 252
+IG FIIAE NH D GA +K Q T + T +Y
Sbjct: 11 KIGEGQRTFIIAEMSANHNQDFDRAVEIIKAAKRSGADAIKLQ-TYTPDTITFDSDNEYF 69
Query: 253 ERPYDNPNSWGKTYGEHKSHLE-FSDTQYR-ELFRYAQEVGILFTASAMDMVSFDFLVNL 426
+ W T HK + E ++ Q++ +L A+E G++ +S D S DFL +
Sbjct: 70 Q--IKQGTIWDGTT-LHKLYEEAYTPWQWQPKLKEIAEEEGLICFSSPFDNTSVDFLEKM 126
Query: 427 KVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQ----FCL 594
+VP K+ S + ++ F++Y ASK P+I+STG+ + + IY+ +++ +Q L
Sbjct: 127 EVPAYKVASFELTDIPFIEYIASKGKPVIMSTGIAE---MGEIYEAVAACRRQGNENVIL 183
Query: 595 LHCISAYPVPFEDCNLTVL 651
L C S+YP P ED NL +
Sbjct: 184 LKCSSSYPSPLEDINLKTI 202
>UniRef50_A3PE56 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. MIT 9301|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain MIT 9301)
Length = 341
Score = 79.0 bits (186), Expect = 9e-14
Identities = 55/188 (29%), Positives = 87/188 (46%), Gaps = 8/188 (4%)
Frame = +1
Query: 112 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTK--KYLERPYDNPNSWG 285
+IAEAG NH G GA +KFQ T E L + NS+
Sbjct: 5 VIAEAGVNHNGSLDLALKLVEEAKLSGADSIKFQ-TFKSESLASFSAPLAQYQKKSNSYK 63
Query: 286 KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSN 465
KS LE +D + +F + E+GI F +S + FL++L + IKI SG+
Sbjct: 64 SQIDMLKS-LELTDKDTKRIFSFCNEIGIEFMSSPFGVDELHFLLDLGMLSIKIPSGEIT 122
Query: 466 NLLFL----KYAASKKIPLIISTGMVDKTAVKTIYDII--SSDHKQFCLLHCISAYPVPF 627
N + K+ + I +++STGM ++ ++ ++ ++HC+S+YP P
Sbjct: 123 NYALISEIGKFISEGNINVLLSTGMSSLGDIEEALSLLRFKETLERITIMHCVSSYPAPN 182
Query: 628 EDCNLTVL 651
+D NL VL
Sbjct: 183 KDLNLKVL 190
>UniRef50_P39625 Cluster: Spore coat polysaccharide biosynthesis
protein spsE; n=2; Bacillus|Rep: Spore coat
polysaccharide biosynthesis protein spsE - Bacillus
subtilis
Length = 373
Score = 79.0 bits (186), Expect = 9e-14
Identities = 56/191 (29%), Positives = 84/191 (43%), Gaps = 3/191 (1%)
Frame = +1
Query: 88 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 267
+G + P FIIAEAG NH G GA VKFQ + + Y + P
Sbjct: 11 VGKDAPVFIIAEAGINHDGKLDQAFALIDAAAEAGADAVKFQMF----QADRMYQKDPGL 66
Query: 268 NPNSWGKTYGEHK--SHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFI 441
+ GK +E L Y +E ++F ++ D S D L +
Sbjct: 67 YKTAAGKDVSIFSLVQSMEMPAEWILPLLDYCREKQVIFLSTVCDEGSADLLQSTSPSAF 126
Query: 442 KIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-HKQFCLLHCISAYP 618
KI S + N+L LKY A P+I ST + + V + I ++ + Q ++HC++ YP
Sbjct: 127 KIASYEINHLPLLKYVARLNRPMIFSTAGAEISDVHEAWRTIRAEGNNQIAIMHCVAKYP 186
Query: 619 VPFEDCNLTVL 651
P E NL+V+
Sbjct: 187 APPEYSNLSVI 197
>UniRef50_Q1GST3 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Alphaproteobacteria|Rep:
N-acylneuraminate-9-phosphate synthase - Sphingopyxis
alaskensis (Sphingomonas alaskensis)
Length = 350
Score = 78.6 bits (185), Expect = 1e-13
Identities = 57/190 (30%), Positives = 75/190 (39%), Gaps = 9/190 (4%)
Frame = +1
Query: 109 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 288
F+IAEAG NH G GA VKFQ E T + Y +
Sbjct: 12 FVIAEAGVNHDGSLDKALRLVDIAVEAGADAVKFQTFRTDEVVTPDAAKAAYQQRQTGAG 71
Query: 289 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN 468
T E LE D + L R+ E GI F ++ + D L+ L + IKI SG+ N
Sbjct: 72 TQYEMIRALELDDAAHERLARHCAERGIEFMSTPFAPWAVDMLLGLGMRRIKIASGEIVN 131
Query: 469 LLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK---------QFCLLHCISAYPV 621
+ A P+I+STGM + V D I + +LHC S YP
Sbjct: 132 KPLIDKVAGSGRPIILSTGMAEMAEVVRAVDWIRTAQSAAGIAMSPGDLVVLHCTSEYPA 191
Query: 622 PFEDCNLTVL 651
P NL +
Sbjct: 192 PAASVNLRAM 201
>UniRef50_Q46675 Cluster: NeuB protein; n=8; Bacteria|Rep: NeuB
protein - Escherichia coli
Length = 346
Score = 77.8 bits (183), Expect = 2e-13
Identities = 58/189 (30%), Positives = 80/189 (42%), Gaps = 8/189 (4%)
Frame = +1
Query: 109 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 288
+I+AE G NH G G + VKFQ T +K + + G+
Sbjct: 5 YIVAEIGCNHNGSVDIAREMILKAKEAGVNAVKFQ-TFKADKLISAIAPKAEYQIKNTGE 63
Query: 289 TYG--EHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 462
E LE Y L YA + + ++ D S DFL +LK KI SG+
Sbjct: 64 LESQLEMTKKLEMKYDDYLHLMEYAVSLNLDVFSTPFDEDSIDFLASLKQKIWKIPSGEL 123
Query: 463 NNLLFLKYAASKKIP---LIISTGMVDKTAVKTIYDIISSDH---KQFCLLHCISAYPVP 624
NL +L+ A IP +IISTGM +K I ++ +LHC + YP P
Sbjct: 124 LNLPYLEKIAKLPIPDKKIIISTGMATIDEIKQSVSIFINNKVPVGNITILHCNTEYPTP 183
Query: 625 FEDCNLTVL 651
FED NL +
Sbjct: 184 FEDVNLNAI 192
>UniRef50_Q1PVV9 Cluster: Similarity to N-acetyl neuramic acid
synthetase NeuB; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similarity to N-acetyl neuramic
acid synthetase NeuB - Candidatus Kuenenia
stuttgartiensis
Length = 277
Score = 77.8 bits (183), Expect = 2e-13
Identities = 53/185 (28%), Positives = 82/185 (44%)
Frame = +1
Query: 97 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPN 276
+N ++IAE G NH GD G VKFQ T L EK P ++P
Sbjct: 12 DNKVYVIAEIGLNHGGDMNTAKRLIDSASKTGVDAVKFQ-TYLTEK------RVPKNSP- 63
Query: 277 SWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 456
+ E ++EL Y + I F ++ D S DFL ++ K+ S
Sbjct: 64 -----IFDILKKCELPFEVFKELKDYTETYNIEFFSTPFDEESVDFLESVNCALYKVASF 118
Query: 457 DSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDC 636
D N L A K +I+S GM + + ++ + I+ + + ++HC+SAYP ED
Sbjct: 119 DVVNYKLLSKIADTKKTIIMSVGMANLSEIEGAFKILKNKTDKLAIMHCVSAYPTKEEDA 178
Query: 637 NLTVL 651
NL+ +
Sbjct: 179 NLSAI 183
>UniRef50_Q30V22 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Desulfovibrio desulfuricans G20|Rep:
N-acylneuraminate-9-phosphate synthase - Desulfovibrio
desulfuricans (strain G20)
Length = 344
Score = 77.0 bits (181), Expect = 4e-13
Identities = 63/194 (32%), Positives = 81/194 (41%), Gaps = 6/194 (3%)
Frame = +1
Query: 88 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 267
I NP F+IAE G NH+GD GA VK Q G+ + +E P
Sbjct: 5 ISDKNPVFVIAEIGGNHEGDFAYARKLVSLAIESGADAVKLQ-VYAGDALVSR-VESPDR 62
Query: 268 NPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 447
N H E S QY L + G+ F ASA D + + V K
Sbjct: 63 N---------RHFKKFELSRGQYEALIDMCRHAGVQFMASAWDRERLGW-IEPHVRIHKA 112
Query: 448 GSGDSNNLLFLKYAASKKIPLIISTGMVD----KTAVKTIYDIISS--DHKQFCLLHCIS 609
GSGD L+ S PL++STG+ + AV+ I + SS + LL C S
Sbjct: 113 GSGDLTAYPMLRALVSTGKPLVLSTGLSTMPEVEAAVRYIGSLDSSYITQGKLALLQCSS 172
Query: 610 AYPVPFEDCNLTVL 651
AYP P D NL V+
Sbjct: 173 AYPCPDGDANLNVM 186
>UniRef50_Q93NQ2 Cluster: NnaB; n=7; Bacteria|Rep: NnaB -
Escherichia coli
Length = 346
Score = 77.0 bits (181), Expect = 4e-13
Identities = 53/186 (28%), Positives = 85/186 (45%), Gaps = 8/186 (4%)
Frame = +1
Query: 109 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 288
+I+AE G NH GD G VKFQ T ++ KY + G
Sbjct: 5 YIVAEIGCNHNGDFNLAKKMVEEAKKAGVDAVKFQ-TFKADQLISKYAPKAEYQIKVTGN 63
Query: 289 TYG--EHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 462
E LE ++ +L YA+E+G+ ++ D S DFL + KI SG+
Sbjct: 64 QESQLEMTRKLELPYEEFIKLEEYAKELGLDVFSTPFDFESIDFLASRNQKMWKIPSGEL 123
Query: 463 NNLLFLKYAASKKI---PLIISTGMVDKTAVKTIYDIISSD---HKQFCLLHCISAYPVP 624
NL +L+ + I +++STGM +K ++++ + ++ +LHC + YP P
Sbjct: 124 LNLPYLEKISRLPIEGKEIVLSTGMATIEEIKASVNVLTKNGMAPEKITILHCNTEYPTP 183
Query: 625 FEDCNL 642
+ED NL
Sbjct: 184 YEDVNL 189
>UniRef50_Q04TP3 Cluster: N-acetylneuraminic acid (Sialic acid)
synthetase; n=6; Bacteria|Rep: N-acetylneuraminic acid
(Sialic acid) synthetase - Leptospira borgpetersenii
serovar Hardjo-bovis (strain JB197)
Length = 364
Score = 77.0 bits (181), Expect = 4e-13
Identities = 55/201 (27%), Positives = 97/201 (48%), Gaps = 4/201 (1%)
Frame = +1
Query: 64 VKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQK---TCLGEK 234
+++ + I G +P ++IAE G NH+G GA KFQ L K
Sbjct: 15 IQLGNKIIAGFFDP-YVIAEIGVNHEGSIDIAKRLIDEAKDGGADGAKFQTYKAETLASK 73
Query: 235 FTKKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDF 414
+ Y +R + S + + ++ S F +Y L ++ Q VGI F ++ D+ + +
Sbjct: 74 NSPSYWDRTQEPTASQFELFKKYDS---FGWKEYEILAKHCQSVGIDFLSTPFDLEAVEH 130
Query: 415 LVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVK-TIYDIISSDHKQFC 591
L + ++PFIK+ S D ++ L+ A P+I+STG + + ++ ++ +
Sbjct: 131 LAS-QMPFIKVASADITSVPLLRSVAKYSKPVILSTGSSTIPEIDFAMRELHANGANEII 189
Query: 592 LLHCISAYPVPFEDCNLTVLQ 654
LLHCI YP E+ NL ++Q
Sbjct: 190 LLHCILNYPTKPENANLGMIQ 210
>UniRef50_Q18EL3 Cluster: Sialic acid synthase; n=1; Haloquadratum
walsbyi DSM 16790|Rep: Sialic acid synthase -
Haloquadratum walsbyi (strain DSM 16790)
Length = 391
Score = 76.6 bits (180), Expect = 5e-13
Identities = 52/178 (29%), Positives = 80/178 (44%), Gaps = 3/178 (1%)
Frame = +1
Query: 118 AEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTYG 297
AE NH G+ GA +K QK + +T++ L Y +P +G TY
Sbjct: 98 AEFTTNHMGNFNVLMRMVEQAVDAGADYIKMQKKDVENFYTEEKLNSNYKSP--YGHTYR 155
Query: 298 EHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNN--- 468
E++ EF T + +++ I + A+ D+ S F++ +P++K+ S +S N
Sbjct: 156 EYRKIFEFDRTDFDRFDEKCEDLDIEWFATPQDIKSLHFVLEYNMPYVKVASTNSRNDEM 215
Query: 469 LLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNL 642
L L+ K L+IS G VK DH L HC+S YPVP E+ L
Sbjct: 216 LTELRDKVPKNTGLVISIGGSTMNEVKDTLSHFP-DHN-IILQHCVSEYPVPPENLGL 271
>UniRef50_A1RHT0 Cluster: N-acylneuraminate-9-phosphate synthase;
n=29; cellular organisms|Rep:
N-acylneuraminate-9-phosphate synthase - Shewanella sp.
(strain W3-18-1)
Length = 349
Score = 74.1 bits (174), Expect = 3e-12
Identities = 54/203 (26%), Positives = 87/203 (42%), Gaps = 5/203 (2%)
Frame = +1
Query: 58 VEVKITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKF 237
++V D IG P F+IAE NH GAS +K Q T +
Sbjct: 1 MQVIKVDHCHIGPGQPVFVIAELSGNHGQSLEKAKEMILAAAEAGASAIKLQ-TYTPDTI 59
Query: 238 TKKYLERPY---DNPNSW-GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVS 405
T + D N W G++ + S ++ LF YA+ +G++ ++ D+ +
Sbjct: 60 TLNVSHGEFFIQDQDNLWKGRSLYDLYSEAMTPWEWHQPLFDYAKSLGLVAFSTPFDLTA 119
Query: 406 FDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH-K 582
++L L VP KI S ++N+ L A P+I+STGM + + ++ +
Sbjct: 120 VEYLEKLNVPCYKIASFENNDHALLAAVAKTGKPVIMSTGMAEIHELAEAVTVLKQHGCR 179
Query: 583 QFCLLHCISAYPVPFEDCNLTVL 651
LL C S YP D NL+ +
Sbjct: 180 DLILLKCTSHYPAEPVDANLSTI 202
>UniRef50_Q89HJ8 Cluster: Blr5992 protein; n=2; Proteobacteria|Rep:
Blr5992 protein - Bradyrhizobium japonicum
Length = 356
Score = 72.9 bits (171), Expect = 6e-12
Identities = 65/211 (30%), Positives = 83/211 (39%), Gaps = 31/211 (14%)
Frame = +1
Query: 112 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQ----KTCLGEKFTKK-YLERPYDNPN 276
IIAEAG NH G GA VKFQ K G K Y +R D
Sbjct: 7 IIAEAGVNHDGSLEKALALVDAAADAGADIVKFQTFNAKALAGGAAKKADYQQRTTDAAE 66
Query: 277 SWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 456
S LE + L A E GI F ++ D S FL++LK+P IKIGSG
Sbjct: 67 SQLAML----ERLELPQAAHHTLIERAAERGIEFLSTPFDDASLGFLLSLKLPRIKIGSG 122
Query: 457 DSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH------------------- 579
D N L AA LI+STGM + ++ +++ +
Sbjct: 123 DLTNAPLLHAAARAGATLILSTGMATLSEIEEALGVLAHGYAQRSDPAGVASFRAAWRDP 182
Query: 580 -------KQFCLLHCISAYPVPFEDCNLTVL 651
+ LLHC + YP P ED NL +
Sbjct: 183 AARATLARHVSLLHCTTEYPCPIEDVNLAAM 213
>UniRef50_Q5QWT8 Cluster: Sialic acid synthase; n=14; Bacteria|Rep:
Sialic acid synthase - Idiomarina loihiensis
Length = 357
Score = 72.9 bits (171), Expect = 6e-12
Identities = 54/157 (34%), Positives = 76/157 (48%), Gaps = 4/157 (2%)
Frame = +1
Query: 112 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKT 291
IIAEAG NH GD GA VKFQ T+K + Y N G+
Sbjct: 4 IIAEAGVNHNGDAKLARDLVTSAHKAGADIVKFQTFKAKNIVTEKATQANYQKKN-LGRE 62
Query: 292 YGE--HKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIGSGDS 462
+ LE S + EL Y E+GI F ++A D S +FLVN L + +K+ SG+
Sbjct: 63 ESQLAMLQRLELSHELHYELVDYCNELGIEFLSTAFDDESLNFLVNDLGLKRLKLPSGEI 122
Query: 463 NNL-LFLKYAASKKIPLIISTGMVDKTAVKTIYDIIS 570
N L LK+A + LI+STGM ++++ +I+
Sbjct: 123 TNAPLVLKHAQT-GCDLIVSTGMATMAEIESVLGVIA 158
>UniRef50_A4MIF1 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Geobacter bemidjiensis Bem|Rep:
N-acylneuraminate-9-phosphate synthase - Geobacter
bemidjiensis Bem
Length = 338
Score = 72.9 bits (171), Expect = 6e-12
Identities = 53/185 (28%), Positives = 84/185 (45%), Gaps = 1/185 (0%)
Frame = +1
Query: 103 PCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSW 282
P +IIAE G N G VK Q T E + K +D N+
Sbjct: 10 PIYIIAEIGGNFT-TFEEAKALVDAAASCGVDAVKLQ-TYRAETVSSK--SAIFDMENTG 65
Query: 283 GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 462
+ E E + +R++F Y + G+ + ++ D L L V KIGS D+
Sbjct: 66 IASQFELFQKYEIDEELHRQVFDYIRAKGLDWFSTPSHEADVDLLDRLGVSAYKIGSDDA 125
Query: 463 NNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDII-SSDHKQFCLLHCISAYPVPFEDCN 639
N+ FL+Y A+K P++++TGM V+ D+I + + + LLH +++YP E N
Sbjct: 126 VNIPFLRYVAAKGKPVLLATGMCTMQEVRESVDVILGAGNLELILLHAVTSYPTHPEHVN 185
Query: 640 LTVLQ 654
L +Q
Sbjct: 186 LLAMQ 190
>UniRef50_Q7VHQ5 Cluster: Sialic acid synthase; n=6;
Helicobacter|Rep: Sialic acid synthase - Helicobacter
hepaticus
Length = 349
Score = 72.5 bits (170), Expect = 8e-12
Identities = 55/189 (29%), Positives = 82/189 (43%), Gaps = 9/189 (4%)
Frame = +1
Query: 112 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPN---SW 282
IIAE NH GA VK Q +T + L + P+ S
Sbjct: 15 IIAELSANHNQSLEIAKDSIRAIAACGADGVKLQT------YTPECLTLQSNEPHFCISG 68
Query: 283 GKTYGEHKSHLEFSDTQ-----YRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKI 447
G + + + + + Q ++ELF A+E+G+L +S FL +L+ P K+
Sbjct: 69 GTLWDKRNLYELYKEAQTPWEWHKELFSLAKELGLLIFSSPFSPKGVAFLESLQCPIYKV 128
Query: 448 GSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISS-DHKQFCLLHCISAYPVP 624
S + + ++ A K P+IISTG+ +KT +I K LLHCIS YP P
Sbjct: 129 ASFEVMHYELIEAIAKTKKPIIISTGVATHKELKTALEICHKYGCKDITLLHCISEYPAP 188
Query: 625 FEDCNLTVL 651
E NL +
Sbjct: 189 LESANLLAM 197
>UniRef50_A3Y8V9 Cluster: NeuB family protein; n=1; Marinomonas sp.
MED121|Rep: NeuB family protein - Marinomonas sp. MED121
Length = 347
Score = 72.1 bits (169), Expect = 1e-11
Identities = 52/186 (27%), Positives = 80/186 (43%), Gaps = 5/186 (2%)
Frame = +1
Query: 109 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 288
FIIAE NH D G +K Q T + T +
Sbjct: 11 FIIAELSGNHNQDFALAKAMIEAAAKTGVDAIKLQ-TYTADSMTLNVRNEEFMVSAQGSL 69
Query: 289 TYGEHKSHLEF-SDTQY---RELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 456
G++ L + T Y + LF YA+ +G++ +S D+ + +FL +L VP KI S
Sbjct: 70 WEGDNLYDLYAKASTPYEWHQPLFDYAKSLGLVAFSSPFDINAVNFLESLDVPIYKIASF 129
Query: 457 DSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIIS-SDHKQFCLLHCISAYPVPFED 633
+ +L ++ A P+I+STGM K+ ++ ++ + LL C S YP ED
Sbjct: 130 ELTDLPLIEAVARTGKPMIMSTGMATKSEIEEAVSLVRLIGDNEITLLKCTSTYPAKIED 189
Query: 634 CNLTVL 651
NL L
Sbjct: 190 SNLITL 195
>UniRef50_UPI0000384B44 Cluster: COG2089: Sialic acid synthase; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG2089:
Sialic acid synthase - Magnetospirillum magnetotacticum
MS-1
Length = 346
Score = 71.7 bits (168), Expect = 1e-11
Identities = 62/188 (32%), Positives = 80/188 (42%), Gaps = 7/188 (3%)
Frame = +1
Query: 109 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGE---KFTKK--YLERPYDNP 273
FIIAEAG NH GD A VKFQ GE +F K YLE +
Sbjct: 14 FIIAEAGVNHDGDIQRAKRLIDVAAEAQADAVKFQTWRPGEITGRFAYKVNYLEATTEQA 73
Query: 274 NSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLV-NLKVPFIKIG 450
S Y E L +REL + + GILF ++ S FLV L +P +KIG
Sbjct: 74 ES---RY-ELSCRLALPYPVFRELKSHCEARGILFLSTPDGFDSLAFLVGELDMPIVKIG 129
Query: 451 SGDSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQFCLLHCISAYPVPF 627
S + + +L+ P I+STG+ V K + + LLHC S YP P
Sbjct: 130 STEVTHPQYLEAIGRTGRPAILSTGLSTLGEVEKAVAALRRGGVGPLALLHCTSEYPAPD 189
Query: 628 EDCNLTVL 651
NL +
Sbjct: 190 SQMNLRAM 197
>UniRef50_A1WSD6 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Verminephrobacter eiseniae EF01-2|Rep:
N-acylneuraminate-9-phosphate synthase -
Verminephrobacter eiseniae (strain EF01-2)
Length = 352
Score = 71.7 bits (168), Expect = 1e-11
Identities = 47/185 (25%), Positives = 79/185 (42%), Gaps = 3/185 (1%)
Frame = +1
Query: 106 CFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWG 285
C +I E G NH G +K Q+ ++ + Y G
Sbjct: 16 CIVIGEIGVNHNRQQDMLFRLIDEGIAAGLDVIKLQRFKAEQEIAMQAPAADYQKRAGAG 75
Query: 286 KTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIGSGDS 462
++ + LE D + F Y ++ G+ F +A D S DFL + L +KI S +
Sbjct: 76 ESQLQMARQLELPDAWLTQAFDYCRQRGVGFLCTAFDHGSVDFLADRLGCKTVKIPSPEV 135
Query: 463 NNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD--HKQFCLLHCISAYPVPFEDC 636
+N L++ A + L++STG V D ++++ ++ L+HC+S YP P E
Sbjct: 136 SNKPLLQHMARRFDGLLLSTGASYLGEVANAIDWLAAEAGPRELALMHCLSEYPAPVEQA 195
Query: 637 NLTVL 651
NL +
Sbjct: 196 NLRAM 200
>UniRef50_Q7NQV6 Cluster: N-acetylneuraminic acid synthase; n=7;
Proteobacteria|Rep: N-acetylneuraminic acid synthase -
Chromobacterium violaceum
Length = 361
Score = 70.5 bits (165), Expect = 3e-11
Identities = 47/145 (32%), Positives = 69/145 (47%), Gaps = 2/145 (1%)
Frame = +1
Query: 100 NPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNS 279
N FIIAEAG NH G GA VKFQ G + + Y +
Sbjct: 2 NHVFIIAEAGVNHNGSLKVALELIDAAKEAGADAVKFQTFKSGAVISMDAPKAEYQKTTT 61
Query: 280 -WGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLV-NLKVPFIKIGS 453
++ + LE S + +L ++ ++ GILF ++ D+ S + LV L VP +K+ S
Sbjct: 62 GTSESQLDMVRKLELSAEDHIQLLQHCEKRGILFLSTPFDVQSAELLVRELGVPQLKVPS 121
Query: 454 GDSNNLLFLKYAASKKIPLIISTGM 528
G+ N FL A +P+I+STGM
Sbjct: 122 GELTNAPFLLKIAGYGLPVIVSTGM 146
>UniRef50_A0LYV7 Cluster: N-acetylneuraminate synthase; n=1;
Gramella forsetii KT0803|Rep: N-acetylneuraminate
synthase - Gramella forsetii (strain KT0803)
Length = 332
Score = 70.5 bits (165), Expect = 3e-11
Identities = 50/181 (27%), Positives = 77/181 (42%)
Frame = +1
Query: 112 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKT 291
+IAE GQ H+G G VKFQ + E LE + KT
Sbjct: 3 VIAEVGQAHEGSLGMALSYIGALAEAGVDAVKFQ-VHIAEA-ESSILEPFRIKFSEQDKT 60
Query: 292 YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 471
++ +EFS +++ + + ++ + F AS + D L + V KIGSG+ NN
Sbjct: 61 RFDYWKRMEFSTDEWKLIKKTCEDNNVEFLASPFSNAAVDLLEEVGVKRYKIGSGEVNNF 120
Query: 472 LFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNLTVL 651
L L+ A +IIS+GM + + F LL C ++YP + L V+
Sbjct: 121 LLLEKIAKTGKQVIISSGMSSFDELDATVSFLRERKISFSLLQCTTSYPTTPANYGLNVI 180
Query: 652 Q 654
Q
Sbjct: 181 Q 181
>UniRef50_Q7MPQ0 Cluster: Sialic acid synthase; n=3;
Proteobacteria|Rep: Sialic acid synthase - Vibrio
vulnificus (strain YJ016)
Length = 357
Score = 69.3 bits (162), Expect = 7e-11
Identities = 48/155 (30%), Positives = 72/155 (46%), Gaps = 2/155 (1%)
Frame = +1
Query: 112 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK- 288
IIAEAG NH GD GA VKFQ T++ + Y N+ +
Sbjct: 4 IIAEAGVNHNGDEALAFKLVDAAHQAGADIVKFQTFKAKNLVTEQAKQADYQVANTQKQE 63
Query: 289 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIGSGDSN 465
+ S LE S + +L ++ + +GI F ++A D S DFLVN L + +K+ SG+
Sbjct: 64 SQLAMLSRLELSYAAHHQLVKHCESLGIEFLSTAFDSESLDFLVNDLGLTRLKLPSGELT 123
Query: 466 NLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIIS 570
N + A LI+STGM ++ +I+
Sbjct: 124 NAPLVLEHARTGCDLIVSTGMATLAEIEMALGVIA 158
>UniRef50_Q726U8 Cluster: NeuB family protein; n=2; Desulfovibrio
vulgaris subsp. vulgaris|Rep: NeuB family protein -
Desulfovibrio vulgaris (strain Hildenborough / ATCC
29579 / NCIMB8303)
Length = 358
Score = 67.7 bits (158), Expect = 2e-10
Identities = 52/178 (29%), Positives = 69/178 (38%), Gaps = 1/178 (0%)
Frame = +1
Query: 112 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKT 291
IIAE G NH GD GA VK Q F L P
Sbjct: 24 IIAEVGLNHGGDADLAWEMIESAWEHGADLVKLQS------FAPGGLLHP-------SLP 70
Query: 292 YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 471
Y + S Q+ LF A+ GI + D + D ++ +K+ S D +N
Sbjct: 71 YAASMEGMMLSLRQHEALFERARRQGIALITTPFDAPTLDLCTRFRIAAVKVASMDLDNT 130
Query: 472 LFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQFCLLHCISAYPVPFEDCNL 642
L+ A +P+I+S GM D + K + + S LLHCIS YP ED L
Sbjct: 131 AHLRAVARTGLPVILSCGMGDHADIGKALATLRESGATDVTLLHCISDYPARLEDMQL 188
>UniRef50_A2BSE7 Cluster: Sialic acid synthase; n=1; Prochlorococcus
marinus str. AS9601|Rep: Sialic acid synthase -
Prochlorococcus marinus (strain AS9601)
Length = 356
Score = 65.7 bits (153), Expect = 9e-10
Identities = 48/181 (26%), Positives = 79/181 (43%), Gaps = 4/181 (2%)
Frame = +1
Query: 112 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQ---KTCLGEKFTKKYLERPYDNPNSW 282
IIAE G NH GD G VKFQ + K +K Y + + S
Sbjct: 23 IIAEIGVNHGGDIDKAIAMIDDVKNNGGDAVKFQTYKANLIARKDSKAYWDTTKEKTMSQ 82
Query: 283 GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDS 462
+ + ++ +F +++++ Y + +LF ++ D S ++ +N K+ S D
Sbjct: 83 FELFSKYD---KFGLEEFKKIEDYCKRKSVLFMSTPFDSYSANY-INQLSKIHKVASVDI 138
Query: 463 NNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHK-QFCLLHCISAYPVPFEDCN 639
N + + AS +I+STG + +K +I S K LLHC+ YP +D N
Sbjct: 139 TNHILISQLASYGKDIILSTGASNLDEIKAAVSLIESKSKISPALLHCVVNYPTLDKDAN 198
Query: 640 L 642
L
Sbjct: 199 L 199
>UniRef50_A4U183 Cluster: N-acetylneuraminate synthase; n=1;
Magnetospirillum gryphiswaldense|Rep:
N-acetylneuraminate synthase - Magnetospirillum
gryphiswaldense
Length = 354
Score = 64.5 bits (150), Expect = 2e-09
Identities = 59/206 (28%), Positives = 89/206 (43%), Gaps = 25/206 (12%)
Frame = +1
Query: 112 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWG-K 288
IIAEAG NH G GA VKFQ + Y N G +
Sbjct: 5 IIAEAGVNHDGKIDQALRLIDAAAAAGADVVKFQTFKAAALASAVAGRAEYQIRNLGGTE 64
Query: 289 TYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVN-LKVPFIKIGSGDSN 465
+ + LE S+ + L + ++ GI F +S D +S +FL++ L + IK+GSG+
Sbjct: 65 SQLDMLRRLELSEDDHFRLRDHCRQAGIGFLSSPFDRLSLEFLIDRLGLDTIKLGSGELT 124
Query: 466 NLLFLKYAASKKIPLIISTGMVD--KTA--------------VKTIYDIISSDH------ 579
N L A + +I+STGM D +TA T +I ++ H
Sbjct: 125 NGPLLLQAGASGRNIILSTGMADLAETAQAVGVIGCGANGVLAPTESEIQAAAHCPSPDL 184
Query: 580 -KQFCLLHCISAYPVPFEDCNLTVLQ 654
++ LLHC + YP P + NL ++
Sbjct: 185 IRRLTLLHCTTEYPAPMDQVNLRAME 210
>UniRef50_Q11RF6 Cluster: N-acetylneuraminic acid synthetase; n=2;
Flexibacteraceae|Rep: N-acetylneuraminic acid synthetase
- Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB
9469)
Length = 348
Score = 64.1 bits (149), Expect = 3e-09
Identities = 50/189 (26%), Positives = 82/189 (43%), Gaps = 4/189 (2%)
Frame = +1
Query: 88 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQK-TCLGEKFTKKYLERPY 264
I N+ F+IAE NH GA +K Q T F E
Sbjct: 9 ISENHKPFVIAEMSGNHNQSLDRALAIVDAAAAAGAHALKLQTYTADTITFNGTSDEFII 68
Query: 265 DNPNSWGKTYGEHKSHLE-FSDTQYRE-LFRYAQEVGILFTASAMDMVSFDFLVNLKVPF 438
+ NS K H+ + + ++ ++ +F A+ G++ +S D + DFL +L VP
Sbjct: 69 KDENSIWKNQNLHQLYQQAYTPWEWHAPIFERAKSHGMIAFSSPFDTTAVDFLESLDVPC 128
Query: 439 IKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDH-KQFCLLHCISAY 615
KI S ++ + + LK A P+I+STG+ ++ ++ + K+ LL C S Y
Sbjct: 129 YKIASFENTDHILLKKVAQTNKPVIMSTGVSTIADIQESVKVLRDNGCKELVLLKCTSTY 188
Query: 616 PVPFEDCNL 642
P E N+
Sbjct: 189 PATPESTNI 197
>UniRef50_A4U173 Cluster: NeuB; n=1; Magnetospirillum
gryphiswaldense|Rep: NeuB - Magnetospirillum
gryphiswaldense
Length = 337
Score = 64.1 bits (149), Expect = 3e-09
Identities = 33/114 (28%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Frame = +1
Query: 316 EFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAAS 495
E + + EL +E+G+ + ++ + D L K GS D N FL+ A
Sbjct: 77 ELTRDDHVELIDLCRELGVAWMSTPSHVSDLDLLEPFDPIAYKTGSDDLTNTRFLRQIAE 136
Query: 496 KKIPLIISTGMVDKTAVKTIYDIIS-SDHKQFCLLHCISAYPVPFEDCNLTVLQ 654
K P+++STGM ++ D+I+ + + + LLHC+ +YP ED NL ++
Sbjct: 137 KGRPMVVSTGMCTLAEIERAVDVITRTGNTELILLHCVVSYPAKAEDANLRAIE 190
>UniRef50_A6W187 Cluster: N-acylneuraminate-9-phosphate synthase;
n=2; Proteobacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Marinomonas sp. MWYL1
Length = 343
Score = 62.9 bits (146), Expect = 6e-09
Identities = 46/186 (24%), Positives = 77/186 (41%), Gaps = 5/186 (2%)
Frame = +1
Query: 109 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPY---DNPNS 279
FIIAE NH D G +K Q T + T + ++ +
Sbjct: 11 FIIAELSGNHDQDFELAKAMIHAAAEAGVDAIKLQ-TYTPDTMTLDVRHGEFMVSESDSL 69
Query: 280 W-GKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 456
W G + ++ LF A+ +G++ +S D+ + FL ++ VP KI S
Sbjct: 70 WRGSNLYDLYKKASTPWEWHKPLFELAESLGLVAFSSPFDLSAVAFLESIDVPLYKIASF 129
Query: 457 DSNNLLFLKYAASKKIPLIISTGMVDKTAV-KTIYDIISSDHKQFCLLHCISAYPVPFED 633
+ ++ ++ A P+I+STGM + + + + I + LL C S YP ED
Sbjct: 130 EMTDIPLIQAVARTGKPIIMSTGMASEEEIAEAVATIRAIGDNPLTLLKCTSTYPSKIED 189
Query: 634 CNLTVL 651
NL +
Sbjct: 190 SNLVTM 195
>UniRef50_Q0YTS4 Cluster: N-acylneuraminate-9-phosphate synthase;
n=5; Bacteria|Rep: N-acylneuraminate-9-phosphate
synthase - Chlorobium ferrooxidans DSM 13031
Length = 354
Score = 61.7 bits (143), Expect = 1e-08
Identities = 46/195 (23%), Positives = 81/195 (41%), Gaps = 7/195 (3%)
Frame = +1
Query: 88 IGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYD 267
+G +P FI+AE NH G GA +K Q T + T + +
Sbjct: 15 LGPGHPAFIVAEMSGNHGGSLEYALEIVHAAKRSGADAIKLQ-TYTADTITLNSDRQDFC 73
Query: 268 NPNSWGKTYGEHKSHLEFSDTQY------RELFRYAQEVGILFTASAMDMVSFDFLVNLK 429
P+ G + +H + + Y +FR A+ + + +S D + + L L
Sbjct: 74 IPS--GTPWADHSTLWSLYNKAYTPWDWHESIFREARSLDLEIFSSPFDESAVELLEQLG 131
Query: 430 VPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVK-TIYDIISSDHKQFCLLHCI 606
KI S + ++ L A P+I+STG+ ++ + + ++ + LL C
Sbjct: 132 ASAYKIASPEITHIPLLDKVARTGKPVILSTGLAALEDIELALATLRAAGSGEIILLKCT 191
Query: 607 SAYPVPFEDCNLTVL 651
+AYP P E+ NL +
Sbjct: 192 TAYPAPIEEANLRTI 206
>UniRef50_Q0P8U0 Cluster: Pse synthetase; n=14; Campylobacter|Rep:
Pse synthetase - Campylobacter jejuni
Length = 343
Score = 61.7 bits (143), Expect = 1e-08
Identities = 52/184 (28%), Positives = 77/184 (41%), Gaps = 6/184 (3%)
Frame = +1
Query: 109 FIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGK 288
FIIAE NH G GA +K Q T + T L ++ G
Sbjct: 13 FIIAELSANHAGSLEMALKSIKAAKKAGADAIKIQ-TYTPDSLT---LNSDKEDFIIKGG 68
Query: 289 TYGEHKSH--LEFSDTQYR---ELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGS 453
+ + K + E + T Y ++F AQ GIL +S +FL KI S
Sbjct: 69 LWDKRKLYELYESAKTPYEWHSQIFETAQNEGILCFSSPFAKEDVEFLKRFDPIAYKIAS 128
Query: 454 GDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSD-HKQFCLLHCISAYPVPFE 630
++N+ F++ A +K P I+STG+ + + I +I + + L C S YP E
Sbjct: 129 FEANDENFVRLIAKEKKPTIVSTGIATEEELFKICEIFKEEKNPDLVFLKCTSTYPTAIE 188
Query: 631 DCNL 642
D NL
Sbjct: 189 DMNL 192
>UniRef50_Q2BI17 Cluster: N-acetylneuraminate synthase; n=4;
Bacteria|Rep: N-acetylneuraminate synthase -
Neptuniibacter caesariensis
Length = 363
Score = 58.8 bits (136), Expect = 1e-07
Identities = 51/201 (25%), Positives = 78/201 (38%), Gaps = 6/201 (2%)
Frame = +1
Query: 70 ITDDIRIGGNNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQK---TCLGEKFT 240
I + I ++P + IA+ NH GD GA KFQ + F
Sbjct: 11 IVNSHSISESDPTYFIADIAANHDGDLEKAKELIWLSAEAGADAAKFQHFKADTIVSDFG 70
Query: 241 KKYLERPYDNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLV 420
K L + ++W K+ E + E EL ++ I F S D D++
Sbjct: 71 FKSLGGQQSHQSTWEKSVYEVYADAEVDLNWTEELVNTCKQAEIDFFTSPYDFDLADYID 130
Query: 421 NLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLH 600
VP KIGSGD L++ A K P ++TG + V + + + L+
Sbjct: 131 QF-VPAHKIGSGDITWHAMLEHIAKKNKPYFLATGASELADVVAAVEACLKINPKLVLMQ 189
Query: 601 CISAYPVPFED---CNLTVLQ 654
C + Y E+ NL VL+
Sbjct: 190 CNTNYTASLENFAYINLNVLK 210
>UniRef50_A4BEM9 Cluster: Sialic acid synthase; n=1; Reinekea sp.
MED297|Rep: Sialic acid synthase - Reinekea sp. MED297
Length = 354
Score = 58.4 bits (135), Expect = 1e-07
Identities = 45/144 (31%), Positives = 61/144 (42%)
Frame = +1
Query: 97 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPN 276
N+ F+IAEAG NH GD GA +KFQ T + E +
Sbjct: 3 NDSVFLIAEAGVNHNGDVELAKELIELAAAAGADAIKFQ-TFIPEALVTTTARKAGYQKT 61
Query: 277 SWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 456
+ ++ L + EL YA I F ++A + S L L V KI SG
Sbjct: 62 AHEESQLAMLQALALPLPVFDELKAYADSKAIEFMSTAFESESLALLSQLAVRRYKIPSG 121
Query: 457 DSNNLLFLKYAASKKIPLIISTGM 528
+ NL FL A+ + LI+STGM
Sbjct: 122 ELTNLPFLIEHAALQQDLILSTGM 145
>UniRef50_Q2IZW6 Cluster: N-acetylneuraminate synthase; n=1;
Rhodopseudomonas palustris HaA2|Rep: N-acetylneuraminate
synthase - Rhodopseudomonas palustris (strain HaA2)
Length = 332
Score = 57.6 bits (133), Expect = 2e-07
Identities = 51/185 (27%), Positives = 73/185 (39%)
Frame = +1
Query: 97 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPN 276
+NP +IIAE G H G GA VKFQ T + E T P
Sbjct: 5 SNP-YIIAEIGSVHDGSFGNACRLLETAAECGADAVKFQ-THIAEAETLPNAPSPSYFSA 62
Query: 277 SWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 456
Y + FS Q+R L A+ + F +S + + D L ++ V KI SG
Sbjct: 63 EPRTAYFKRTG---FSPEQWRALAALAKSTKVDFLSSPFSLEAVDLLEDVGVAAYKIPSG 119
Query: 457 DSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDC 636
+ +N+ L A P+ +S+GM + + + LL C S YP P E
Sbjct: 120 EVSNIPLLSRIAQTGKPVFLSSGMSNWEELDAAVGALRG--SALTLLQCTSKYPCPPEQV 177
Query: 637 NLTVL 651
L +
Sbjct: 178 GLNAM 182
>UniRef50_Q0AN71 Cluster: N-acetylneuraminate synthase; n=1;
Maricaulis maris MCS10|Rep: N-acetylneuraminate synthase
- Maricaulis maris (strain MCS10)
Length = 305
Score = 57.2 bits (132), Expect = 3e-07
Identities = 47/181 (25%), Positives = 75/181 (41%), Gaps = 1/181 (0%)
Frame = +1
Query: 112 IIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKT 291
+IAE G NH GD GA VKFQ T E +++ + D +
Sbjct: 6 VIAEIGSNHGGDLDQAKRYIEASAKAGADVVKFQ-TLTREGLIARFV-KGADGTVTENPK 63
Query: 292 YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 471
+ + D + L A + G+ F ++ + + + + +L V KI SGD
Sbjct: 64 FAAF-GNAGLPDDWHAPLMTCAADNGVEFMSTPFSLDAVELMESLGVKRYKIASGDLTFT 122
Query: 472 LFLKYAASKKIPLIISTGMVDKTAVKT-IYDIISSDHKQFCLLHCISAYPVPFEDCNLTV 648
L+ + LI+STG V T + + S LHC ++YP +ED NL+
Sbjct: 123 PLLEALGATGKRLILSTGASYLDEVTTAVTTLTRSGCPHLTALHCAASYPPAWEDLNLSA 182
Query: 649 L 651
+
Sbjct: 183 I 183
>UniRef50_O83573 Cluster: Spore coat polysaccharide biosynthesis
protein; n=1; Treponema pallidum|Rep: Spore coat
polysaccharide biosynthesis protein - Treponema pallidum
Length = 378
Score = 56.4 bits (130), Expect = 6e-07
Identities = 50/182 (27%), Positives = 74/182 (40%), Gaps = 3/182 (1%)
Frame = +1
Query: 115 IAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTY 294
IAE G H G A+ VKFQ E L P+ Y
Sbjct: 18 IAEIGSAHAGSFDRARALIDAAADAAAAAVKFQLIYAHEILHP--LTGAVRLPSGAVSLY 75
Query: 295 GEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLL 474
+ LE + Y + F +A+ G+L S S + LK F+K+ S + N
Sbjct: 76 -QRFEELEVPLSFYAQCFNHARSRGMLVGISPFGPRSATEALALKPDFLKVASPELNYPT 134
Query: 475 FLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQ---FCLLHCISAYPVPFEDCNLT 645
+ A+ ++PLI+S+G+ ++ KQ LLHCI+AYP P + NL
Sbjct: 135 LISTLAAAELPLILSSGVCLLKEIEGALAQCRQYTKQGSSHALLHCITAYPAPETEYNLA 194
Query: 646 VL 651
+L
Sbjct: 195 LL 196
>UniRef50_Q3B0R9 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Synechococcus sp. CC9902|Rep:
N-acylneuraminate-9-phosphate synthase - Synechococcus
sp. (strain CC9902)
Length = 349
Score = 56.0 bits (129), Expect = 7e-07
Identities = 48/192 (25%), Positives = 76/192 (39%), Gaps = 7/192 (3%)
Frame = +1
Query: 97 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQK----TCLGEKFTKKYLERPY 264
+NP + IA+ G NH GA KFQ + + + K+
Sbjct: 7 DNPLYFIADIGANHDSSLKRAKALIKTAAESGADAAKFQNFFAHSIVSDLGFKQLPNSIL 66
Query: 265 DNPNSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIK 444
+ W ++ + S EL Y +E GI + + D+ +FL N V K
Sbjct: 67 SHQAEWTESVFDVYDKASLSLEWTEELHSYCKECGISYMTTPYDISILEFL-NQYVACWK 125
Query: 445 IGSGDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYP-- 618
IGSGD L + + P+ I+TG + T V + + K+ L+ C + Y
Sbjct: 126 IGSGDITWLDLISKVSQLGKPIAIATGASNFTEVCQAVNTVLQHTKKIILMQCNTNYTGC 185
Query: 619 -VPFEDCNLTVL 651
F+ NL+VL
Sbjct: 186 LSNFDYLNLSVL 197
>UniRef50_A0LAB4 Cluster: N-acetylneuraminic acid synthase,
N-terminal domain; n=2; Proteobacteria|Rep:
N-acetylneuraminic acid synthase, N-terminal domain -
Magnetococcus sp. (strain MC-1)
Length = 500
Score = 53.6 bits (123), Expect = 4e-06
Identities = 48/187 (25%), Positives = 75/187 (40%), Gaps = 6/187 (3%)
Frame = +1
Query: 109 FIIAEAGQN----HQG-DXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNP 273
+IIAEAG N H D GA VKFQ + + + Y
Sbjct: 161 YIIAEAGSNWRMGHPARDLAMGKALIDAAVVSGADAVKFQTYRPEKVYVANAGQSNYLAE 220
Query: 274 NSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGS 453
+ + + + L + +L Y ++ GI F ++ + F ++ VP KI S
Sbjct: 221 SGIKQDIRDIFADLAMPYSMIEDLAGYCKKAGIQFLSTGFSVEDFQ-AIDPWVPLHKIAS 279
Query: 454 GDSNNLLFLKYAASKKIPLIISTGMVDKTAVK-TIYDIISSDHKQFCLLHCISAYPVPFE 630
+ ++L L AA+ PL++STG + + S + CLL C + YP P
Sbjct: 280 YEISHLRLLDLAANSGKPLLLSTGASRAEDIAWAVERYHSQGGRDLCLLQCTAKYPAPLA 339
Query: 631 DCNLTVL 651
N VL
Sbjct: 340 TVNSAVL 346
>UniRef50_Q2BJD7 Cluster: N-acetylneuraminic acid synthetase; n=1;
Neptuniibacter caesariensis|Rep: N-acetylneuraminic acid
synthetase - Neptuniibacter caesariensis
Length = 270
Score = 51.6 bits (118), Expect = 2e-05
Identities = 44/179 (24%), Positives = 73/179 (40%), Gaps = 3/179 (1%)
Frame = +1
Query: 115 IAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPNSWGKTY 294
IAE G N GD GA+ KFQ +K +DN G+
Sbjct: 4 IAEIGWNFMGDMKLAEDMIAAAAQSGATTAKFQYWN-----PEKLKAGAWDND---GRRE 55
Query: 295 GEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLL 474
+K+ L Q +L + + F S + +F+ IKI S + N+
Sbjct: 56 IYNKACLNADKIQ--QLTELCSKHNVKFLLSVFNKEDAEFVSQFSTEAIKIPSHEVANIE 113
Query: 475 FLKYAASKKIPLIISTGMVDKTAVKTIYDIISS---DHKQFCLLHCISAYPVPFEDCNL 642
++YA S + +S G + +K + +++ S + + +HC+S+YP P E NL
Sbjct: 114 LIRYALSTYKRVFLSLGACTEEELKDVSELVGSIRSNGEDVVAMHCVSSYPCPVEKVNL 172
>UniRef50_Q8EC83 Cluster: Polysaccharide biosynthesis
related-protein; n=6; Proteobacteria|Rep: Polysaccharide
biosynthesis related-protein - Shewanella oneidensis
Length = 290
Score = 51.2 bits (117), Expect = 2e-05
Identities = 54/192 (28%), Positives = 78/192 (40%), Gaps = 7/192 (3%)
Frame = +1
Query: 97 NNPCFIIAEAGQNHQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNPN 276
++P FI AE NH D G VKFQ + E F + L +
Sbjct: 4 HSPLFI-AEVSSNHHRDLQRCIEFIKTAAEIGCDAVKFQLFKIEELFAPEILSK------ 56
Query: 277 SWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSG 456
+ E + +L + E GI F+ + + D + L+ PF+
Sbjct: 57 ---SEMHRKRKEWELPVSFLPQLKQSCDEYGIQFSCTPFYL---DAVAELE-PFVDFYKI 109
Query: 457 DSNNLLF---LKYAASKKIPLIISTGMVD----KTAVKTIYDIISSDHKQFCLLHCISAY 615
S LL+ L P++IS GM A+KT+ + +SD LLHC+SAY
Sbjct: 110 ASYELLWDDLLAACVKTGKPVVISAGMATIEEIDHALKTLKENGASD---ITLLHCVSAY 166
Query: 616 PVPFEDCNLTVL 651
P P +CNL VL
Sbjct: 167 PTPEHECNLAVL 178
>UniRef50_A7DQU2 Cluster: N-acylneuraminate-9-phosphate synthase;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
N-acylneuraminate-9-phosphate synthase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 351
Score = 51.2 bits (117), Expect = 2e-05
Identities = 44/187 (23%), Positives = 70/187 (37%), Gaps = 6/187 (3%)
Frame = +1
Query: 109 FIIAEAGQN-----HQGDXXXXXXXXXXXXXXGASCVKFQKTCLGEKFTKKYLERPYDNP 273
F+IAEAG N + D GA VKFQ + Y
Sbjct: 14 FVIAEAGSNWKCGDYSDDLEQAKKLIETAAKAGADAVKFQTYKPETIYVSDAGNSDYLEK 73
Query: 274 NSWGKTYGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGS 453
+ E HL EL +Y E I F ++ + V+ K+ S
Sbjct: 74 YGIKENINEIFEHLSMPYEMIPELKKYCDEKNIQFMSTPFSVQDAKE-VDKFTEIHKVAS 132
Query: 454 GDSNNLLFLKYAASKKIPLIISTGMVDKTAVKTIYDII-SSDHKQFCLLHCISAYPVPFE 630
+ N++ L++ A + P+I+STG + ++I + + L+ C S YP P +
Sbjct: 133 FEINHIRLLEFLAKTQKPIIVSTGASTFKEIDFAINLIRKNGNDNIALMQCTSKYPCPID 192
Query: 631 DCNLTVL 651
NL +
Sbjct: 193 SLNLKTI 199
>UniRef50_A5W0I0 Cluster: N-acetylneuraminic acid synthase,
N-terminal domain; n=1; Pseudomonas putida F1|Rep:
N-acetylneuraminic acid synthase, N-terminal domain -
Pseudomonas putida F1
Length = 369
Score = 49.2 bits (112), Expect = 9e-05
Identities = 28/117 (23%), Positives = 48/117 (41%)
Frame = +1
Query: 292 YGEHKSHLEFSDTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNL 471
Y + + ++ + + + + A+ D S D V +P IKI S D N+
Sbjct: 74 YVKKTEDTRLTKAEFARMVEEVRNLSCIPMATPFDEASVDLCVEFDMPIIKIASSDMNDW 133
Query: 472 LFLKYAASKKIPLIISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNL 642
++ AS + P IISTG + + I + HC+S YP ++ L
Sbjct: 134 PLIEKIASTRRPTIISTGGASEKDLDDIVRYFEKRDIPLAINHCVSLYPSEDDELQL 190
>UniRef50_Q319P5 Cluster: Putative spore coat polysaccharide
biosynthesis protein E; n=1; Prochlorococcus marinus
str. MIT 9312|Rep: Putative spore coat polysaccharide
biosynthesis protein E - Prochlorococcus marinus (strain
MIT 9312)
Length = 521
Score = 44.8 bits (101), Expect = 0.002
Identities = 27/110 (24%), Positives = 46/110 (41%), Gaps = 1/110 (0%)
Frame = +1
Query: 325 DTQYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKI 504
D Q+ ++ ++ G + D S + + KI S L+ A++
Sbjct: 88 DEQWLQILNMVRDKGFKTIVTPFDEASVNKAERFGIEEYKIASCSCTEWSLLREVANQNK 147
Query: 505 PLIISTGMVDKTAVKTIYDIISSDHK-QFCLLHCISAYPVPFEDCNLTVL 651
P+ ISTG + V IY + +F ++HC YP P +D NL +
Sbjct: 148 PVTISTGGRNLKEVDDIYSYFAHRIPYKFTIMHCCGIYPAPIKDLNLNTI 197
>UniRef50_Q0IDQ4 Cluster: NeuB family protein; n=1; Synechococcus
sp. CC9311|Rep: NeuB family protein - Synechococcus sp.
(strain CC9311)
Length = 353
Score = 44.8 bits (101), Expect = 0.002
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 2/109 (1%)
Frame = +1
Query: 331 QYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPL 510
Q+RELF + G+ F S + S DF V+ IKI S + N L ++ +A +PL
Sbjct: 96 QHRELFNLIKSYGLNFIVSVYTLESVDFAVSEGAIAIKIASSNINFLPLIEKSARTGLPL 155
Query: 511 IISTGMVDKTAVKTIYDIISSDHKQFCLL--HCISAYPVPFEDCNLTVL 651
+I TG + S ++ L+ H +A P P E +L+ +
Sbjct: 156 LIDTGKSTLCEIFEARHAAYSANQDVKLIFEHSPAAPPAPIERQDLSFM 204
>UniRef50_UPI0000F219ED Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 100
Score = 37.5 bits (83), Expect = 0.28
Identities = 15/36 (41%), Positives = 24/36 (66%)
Frame = +1
Query: 391 MDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASK 498
MD ++ +FL + VPF K+ S D+NN+ +L+ A K
Sbjct: 1 MDEMAVEFLHEINVPFFKVASADTNNIPYLEKTAKK 36
>UniRef50_A5IGD9 Cluster: Spore coat polysaccharide biosynthesis
protein E; n=5; Legionella pneumophila|Rep: Spore coat
polysaccharide biosynthesis protein E - Legionella
pneumophila (strain Corby)
Length = 368
Score = 37.1 bits (82), Expect = 0.37
Identities = 25/108 (23%), Positives = 48/108 (44%), Gaps = 1/108 (0%)
Frame = +1
Query: 334 YRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLI 513
Y LF + + F S ++ + DF + +K S + ++ +++ A +PLI
Sbjct: 107 YSMLFSLLKNANLPFIVSIYELDTIDFAIKQGACALKTSSSNIVHIPLIRHLAKTGLPLI 166
Query: 514 ISTGMVDKTAV-KTIYDIISSDHKQFCLLHCISAYPVPFEDCNLTVLQ 654
I TG T + K + S+ ++ + H +P E NL +L+
Sbjct: 167 IDTGRSSLTDICKAVETAKSAGCEKIIIEHSPDGHPALPEAHNLRMLR 214
>UniRef50_Q7NR94 Cluster: Probable spore coat polysaccharide
biosynthesis protein E; n=1; Chromobacterium
violaceum|Rep: Probable spore coat polysaccharide
biosynthesis protein E - Chromobacterium violaceum
Length = 495
Score = 35.9 bits (79), Expect = 0.85
Identities = 22/104 (21%), Positives = 42/104 (40%)
Frame = +1
Query: 331 QYRELFRYAQEVGILFTASAMDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPL 510
Q ++L + G + D S D + + IKI S + L+ A P+
Sbjct: 77 QMQKLVAEMKANGFKAICTPFDEESVDLIEAHGIEIIKIASCSFTDWPLLERIARSDKPV 136
Query: 511 IISTGMVDKTAVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNL 642
+ ST + + + + K ++HC++ YP P + +L
Sbjct: 137 VASTAGARREDIDKVVSFMLHRGKDLTIMHCVAEYPTPDDHLHL 180
>UniRef50_Q8RI47 Cluster: Tetratricopeptide repeat family protein;
n=1; Fusobacterium nucleatum subsp. nucleatum|Rep:
Tetratricopeptide repeat family protein - Fusobacterium
nucleatum subsp. nucleatum
Length = 628
Score = 34.3 bits (75), Expect = 2.6
Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +1
Query: 358 QEVGILFTASA-MDMVSFDFLVNLKVPFIKIGSGDSNNLLFLKYAASKKIPLIISTGMVD 534
+E+GI +T S D+++ + NL FIK+ SG+ Y K M+D
Sbjct: 548 EEIGIFYTPSGKQDIINNKY--NLPEDFIKLKSGEIKTFFIDWYNNKTKEKFYELFNMID 605
Query: 535 KTAVKTIYDIISSDHK 582
KT++K ++++ K
Sbjct: 606 KTSIKVYLKYLNTEKK 621
>UniRef50_Q5A950 Cluster: Sterol 3-beta-glucosyltransferase; n=2;
Candida albicans|Rep: Sterol 3-beta-glucosyltransferase -
Candida albicans (Yeast)
Length = 1513
Score = 33.9 bits (74), Expect = 3.4
Identities = 21/68 (30%), Positives = 34/68 (50%), Gaps = 4/68 (5%)
Frame = +1
Query: 208 FQKTCLG--EKFTKKYLERPYDNPNSWGKTYGE--HKSHLEFSDTQYRELFRYAQEVGIL 375
FQK L E+ K RP P WG + +K+ +E+SD++ RE+ +Y + I
Sbjct: 912 FQKVVLSVLERLHSKEGFRP--EPYQWGSNFEVELYKTRMEYSDSENREIQQYDNSIDIK 969
Query: 376 FTASAMDM 399
F ++M
Sbjct: 970 FAEKKIEM 977
>UniRef50_Q54FM7 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 888
Score = 33.1 bits (72), Expect = 6.0
Identities = 35/154 (22%), Positives = 66/154 (42%), Gaps = 6/154 (3%)
Frame = +1
Query: 199 CVKFQKTCLGEKFTKKYLERPYDNPNSWGKTY-GEHKSHLEFSDTQYRELFRYAQEVG-- 369
C +F K E F K + Y N NS KT H ++ E ++ ++ ++
Sbjct: 379 CYRFNKDRCLESFLIKQFRKTYSNSNSNSKTVLFSHCNNKEKQIEFINQVIKFKNDLPNP 438
Query: 370 ILFTASAMDMVSFDFLVNLKVPFI---KIGSGDSNNLLFLKYAASKKIPLIISTGMVDKT 540
+LF + S + + ++ F + ++NNLL K + KIP II+ +
Sbjct: 439 LLFFYLVISFDSLELIKMVEKGFTDNNNNNNNNNNNLLEYKETYNNKIPFIITRYIRSIQ 498
Query: 541 AVKTIYDIISSDHKQFCLLHCISAYPVPFEDCNL 642
++ +++ +HK + S+Y F + NL
Sbjct: 499 VMEYLFE----NHKNHFIQTSSSSYISFFINLNL 528
>UniRef50_Q8IFK4 Cluster: Hemoglobin A1 chain; n=2;
Vestimentifera|Rep: Hemoglobin A1 chain - Riftia
pachyptila (Tube worm)
Length = 115
Score = 32.7 bits (71), Expect = 7.9
Identities = 15/50 (30%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Frame = +1
Query: 280 WGKTYGEHKSHLEFSDTQYRELFRYAQEVGILF-TASAMDMVSFDFLVNL 426
W K YG + +F D +R +F YA +F + ++ DM S +F ++
Sbjct: 1 WAKAYGIGAARSKFGDALWRNVFNYAPNARDIFESVNSKDMASPEFKAHI 50
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 639,686,807
Number of Sequences: 1657284
Number of extensions: 12444864
Number of successful extensions: 29633
Number of sequences better than 10.0: 89
Number of HSP's better than 10.0 without gapping: 28674
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 29512
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 49173558301
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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