Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fprWP07_F_M09
(669 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella ve... 266 2e-70
UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondr... 253 2e-66
UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondri... 249 5e-65
UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52; cell... 244 2e-63
UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63; Euka... 243 4e-63
UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Ma... 235 5e-61
UniRef50_A0L5P5 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 234 2e-60
UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplas... 231 1e-59
UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon nigrovirid... 229 6e-59
UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|R... 225 1e-57
UniRef50_A7CWP9 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 220 2e-56
UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole geno... 217 3e-55
UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma japonicu... 215 6e-55
UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;... 211 1e-53
UniRef50_Q0AIF8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 207 2e-52
UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187; cell... 203 3e-51
UniRef50_A7IMB8 Cluster: Malate dehydrogenase (Oxaloacetate-deca... 199 6e-50
UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila melanogas... 197 2e-49
UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor circinelloides... 194 2e-48
UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2; Ostre... 189 5e-47
UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic... 187 2e-46
UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isofo... 183 3e-45
UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Mali... 182 5e-45
UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:... 182 9e-45
UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep... 181 2e-44
UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20; Trypanoso... 180 2e-44
UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 178 9e-44
UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,... 177 1e-43
UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase (... 176 3e-43
UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;... 176 5e-43
UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 175 1e-42
UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep: ... 169 4e-41
UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6; Deinococci|... 169 7e-41
UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2; ... 167 2e-40
UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus californi... 165 9e-40
UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:... 165 1e-39
UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10; Franc... 163 5e-39
UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:... 163 5e-39
UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:... 162 8e-39
UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2; Ostr... 151 1e-35
UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme; ... 150 3e-35
UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Ma... 149 5e-35
UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|R... 148 1e-34
UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia intestinalis... 147 2e-34
UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep: ... 142 5e-33
UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2; Mucoromyco... 142 5e-33
UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2; Aeromo... 140 3e-32
UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 138 8e-32
UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Mali... 136 3e-31
UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3; Schizo... 136 6e-31
UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep: ... 135 1e-30
UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondri... 133 4e-30
UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella neofo... 124 2e-27
UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n... 121 1e-26
UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium globosum|... 115 9e-25
UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococc... 115 1e-24
UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Ma... 95 1e-18
UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15... 90 5e-17
UniRef50_A5C6I9 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep: ... 77 5e-13
UniRef50_Q8S484 Cluster: Putative NADP-dependent malic enzyme; n... 61 3e-08
UniRef50_UPI0000DB7FF6 Cluster: PREDICTED: hypothetical protein,... 42 0.010
UniRef50_P54572 Cluster: Probable NAD-dependent malic enzyme 1; ... 42 0.013
UniRef50_Q3W7J3 Cluster: Malate dehydrogenase; n=1; Frankia sp. ... 42 0.018
UniRef50_Q8U225 Cluster: Malate oxidoreductase; n=41; cellular o... 42 0.018
UniRef50_Q5Y0M3 Cluster: Malate oxidoreductase; n=8; cellular or... 40 0.054
UniRef50_Q2KKD0 Cluster: Oxalacetate decarboxylase; n=11; Lactob... 39 0.095
UniRef50_A0DE35 Cluster: Malic enzyme; n=3; Paramecium tetraurel... 39 0.095
UniRef50_Q9HKY7 Cluster: Malate oxidoreductase (Malic enzyme) re... 37 0.51
UniRef50_UPI00006CF21C Cluster: Bowman-Birk serine protease inhi... 36 0.67
UniRef50_Q2STW7 Cluster: Putative uncharacterized protein; n=1; ... 34 2.7
UniRef50_Q116W6 Cluster: Putative uncharacterized protein; n=1; ... 34 2.7
UniRef50_Q08PM3 Cluster: Hemin ABC transporter, periplasmic hemi... 34 2.7
UniRef50_A7PY09 Cluster: Chromosome chr15 scaffold_37, whole gen... 34 2.7
UniRef50_A1CKF3 Cluster: Stress response protein (Ish1), putativ... 34 2.7
UniRef50_UPI0000DA40E4 Cluster: PREDICTED: hypothetical protein;... 34 3.6
UniRef50_Q4SHK3 Cluster: Chromosome 5 SCAF14581, whole genome sh... 34 3.6
UniRef50_Q8R7R6 Cluster: Malic enzyme; n=10; cellular organisms|... 34 3.6
UniRef50_Q5SLE4 Cluster: CBS domain protein; n=7; Bacteria|Rep: ... 34 3.6
UniRef50_Q4DMA9 Cluster: Mucin TcMUCII, putative; n=4; Trypanoso... 34 3.6
UniRef50_UPI0000F2DA74 Cluster: PREDICTED: hypothetical protein;... 33 4.7
UniRef50_Q4RNM6 Cluster: Chromosome 21 SCAF15012, whole genome s... 33 4.7
UniRef50_Q0STR8 Cluster: Malate oxidoreductase; n=2; Clostridium... 33 4.7
UniRef50_A4AEE1 Cluster: Dihydroorotase and related cyclic amido... 33 4.7
UniRef50_UPI0001560FE5 Cluster: PREDICTED: similar to KIAA2007 p... 33 6.2
UniRef50_P16468 Cluster: NAD-dependent malic enzyme; n=32; Bacte... 33 6.2
UniRef50_Q1EI20 Cluster: Putative uncharacterized protein; n=2; ... 33 8.2
UniRef50_A0WC26 Cluster: Multi-sensor hybrid histidine kinase pr... 33 8.2
UniRef50_Q8PTT0 Cluster: NAD-dependent malic enzyme; n=4; cellul... 33 8.2
>UniRef50_A7T6B8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 365
Score = 266 bits (653), Expect = 2e-70
Identities = 120/184 (65%), Positives = 146/184 (79%)
Frame = +2
Query: 104 LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKY 283
+ G D ++ LNKG+AFT+EERQ+LGIHGLLPP V +QE Q + + R N L KY
Sbjct: 13 IRGTDIMRDSHLNKGLAFTLEERQILGIHGLLPPCVISQEIQAQRVYRELQRKPNDLEKY 72
Query: 284 IYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGH 463
I LM LL+RNE LF+R + D E+MPIVYTPTVGLAC+K+G+++RRPRGLFI+IHDKGH
Sbjct: 73 IQLMALLERNESLFFRVLFDYTEELMPIVYTPTVGLACRKYGMIFRRPRGLFISIHDKGH 132
Query: 464 VYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPIT 643
+ D++ NWP T+V+AIV+TDGERILGLGDLG CGMGIPVGKLALYT GGI P CLP+
Sbjct: 133 IRDIVSNWPTTEVKAIVMTDGERILGLGDLGCCGMGIPVGKLALYTVCGGIDPEGCLPVM 192
Query: 644 IDVG 655
IDVG
Sbjct: 193 IDVG 196
>UniRef50_Q16798 Cluster: NADP-dependent malic enzyme, mitochondrial
precursor; n=15; Bilateria|Rep: NADP-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 604
Score = 253 bits (620), Expect = 2e-66
Identities = 116/182 (63%), Positives = 142/182 (78%)
Frame = +2
Query: 110 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIY 289
G D ++P LNKGMAFT+EER LGIHGL+PP +Q+ Q+ +R ++ L+KYI
Sbjct: 50 GYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYII 109
Query: 290 LMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVY 469
LM L DRNE LFYR + +V + MPIVYTPTVGLACQ +GL +RRPRGLFITIHDKGH+
Sbjct: 110 LMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLA 169
Query: 470 DVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 649
+L +WPE +++A+VVTDGERILGLGDLG GMGIPVGKLALYTA GG+ P QCLP+ +D
Sbjct: 170 TMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLD 229
Query: 650 VG 655
VG
Sbjct: 230 VG 231
>UniRef50_P23368 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=53; Eumetazoa|Rep: NAD-dependent malic
enzyme, mitochondrial precursor - Homo sapiens (Human)
Length = 584
Score = 249 bits (609), Expect = 5e-65
Identities = 107/179 (59%), Positives = 143/179 (79%)
Frame = +2
Query: 128 HPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLD 307
+P NKGMAFT++ERQ+LG+ GLLPP+++TQ+ Q ++ + +PL KYIY+MG+ +
Sbjct: 31 NPRTNKGMAFTLQERQMLGLQGLLPPKIETQDIQALRFHRNLKKMTSPLEKYIYIMGIQE 90
Query: 308 RNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW 487
RNE LFYR + D++ +MPIVYTPTVGLAC ++G ++RRP+GLFI+I D+GHV ++ NW
Sbjct: 91 RNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIVDNW 150
Query: 488 PETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGYEH 664
PE V+A+VVTDGERILGLGDLG GMGIPVGKL LYTA GI+P +CLP+ IDVG ++
Sbjct: 151 PENHVKAVVVTDGERILGLGDLGVYGMGIPVGKLCLYTACAGIRPDRCLPVCIDVGTDN 209
>UniRef50_P06801 Cluster: NADP-dependent malic enzyme; n=52;
cellular organisms|Rep: NADP-dependent malic enzyme -
Mus musculus (Mouse)
Length = 572
Score = 244 bits (597), Expect = 2e-63
Identities = 114/180 (63%), Positives = 138/180 (76%)
Frame = +2
Query: 125 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLL 304
+ P LNK +AFT+EERQ L IHGLLPP + +QE QV + +R + ++Y+ LM L
Sbjct: 20 RDPHLNKDLAFTLEERQQLNIHGLLPPCIISQELQVLRIIKNFERLNSDFDRYLLLMDLQ 79
Query: 305 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 484
DRNE LFY + +V + MPIVYTPTVGLACQ++ L +R+PRGLFI+IHDKGH+ VL
Sbjct: 80 DRNEKLFYSVLMSDVEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNA 139
Query: 485 WPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGYEH 664
WPE V+AIVVTDGERILGLGDLG GMGIPVGKLALYTA GG+ P QCLPIT+DVG E+
Sbjct: 140 WPEDVVKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPITLDVGTEN 199
>UniRef50_P48163 Cluster: NADP-dependent malic enzyme; n=63;
Eukaryota|Rep: NADP-dependent malic enzyme - Homo
sapiens (Human)
Length = 572
Score = 243 bits (594), Expect = 4e-63
Identities = 110/180 (61%), Positives = 138/180 (76%)
Frame = +2
Query: 125 KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLL 304
++P LNK +AFT+EERQ L IHGLLPP +QE QV + + + ++Y+ LM L
Sbjct: 20 RNPHLNKDLAFTLEERQQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQ 79
Query: 305 DRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKN 484
DRNE LFYR + ++ + MPIVYTPTVGLACQ++ LV+R+PRGLFITIHD+GH+ VL
Sbjct: 80 DRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASVLNA 139
Query: 485 WPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGYEH 664
WPE ++AIVVTDGERILGLGDLG GMGIPVGKLALYTA GG+ P +CLP+ +DVG E+
Sbjct: 140 WPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQECLPVILDVGTEN 199
>UniRef50_A2ZQ54 Cluster: Malic enzyme; n=9; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 613
Score = 235 bits (576), Expect = 5e-61
Identities = 106/183 (57%), Positives = 142/183 (77%)
Frame = +2
Query: 107 SGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYI 286
SG L+ P NKG+AF+ +ER + GLLPP V +Q+ QV+ ++ +Y PL +Y+
Sbjct: 99 SGYTLLRDPHHNKGLAFSEKERDAHYLRGLLPPAVVSQDLQVKKIMHNLRQYSVPLQRYM 158
Query: 287 YLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHV 466
+M L +RNE LFY+ + DNV E++P+VYTPTVG ACQK+G ++R+P+GL++++ DKG V
Sbjct: 159 AMMDLQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRQPQGLYVSLKDKGKV 218
Query: 467 YDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITI 646
DVL+NWPE +++ IVVTDGERILGLGDLG GMGIPVGKL+LYTALGG++P CLPITI
Sbjct: 219 LDVLRNWPERNIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGVRPSACLPITI 278
Query: 647 DVG 655
DVG
Sbjct: 279 DVG 281
>UniRef50_A0L5P5 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Magnetococcus sp. MC-1|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Magnetococcus
sp. (strain MC-1)
Length = 556
Score = 234 bits (572), Expect = 2e-60
Identities = 111/187 (59%), Positives = 137/187 (73%)
Frame = +2
Query: 95 TSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 274
T + L+ L P +NKG+AFT EER L + GLLPPRV+T E Q+ + N L
Sbjct: 14 TGHANPLEILNDPYMNKGVAFTEEERDLFHLRGLLPPRVQTMEAQLGRALDNFRCKPNDL 73
Query: 275 NKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHD 454
KYI+L GL +RNE LFYR V N+ EM+PI+YTPTVG ACQ +G ++RRP+G+FI+I+D
Sbjct: 74 EKYIFLTGLQERNETLFYRLVMTNIEEMLPIIYTPTVGKACQTYGHIFRRPQGMFISIND 133
Query: 455 KGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCL 634
KG + ++L NW DVR IVVTDG RILGLGDLGA GMGIPVGKLALYTAL GI P CL
Sbjct: 134 KGRIAELLGNWVHKDVRVIVVTDGSRILGLGDLGAHGMGIPVGKLALYTALAGIPPIHCL 193
Query: 635 PITIDVG 655
P+T+D+G
Sbjct: 194 PVTLDMG 200
>UniRef50_P16243 Cluster: NADP-dependent malic enzyme, chloroplast
precursor; n=79; Magnoliophyta|Rep: NADP-dependent malic
enzyme, chloroplast precursor - Zea mays (Maize)
Length = 636
Score = 231 bits (565), Expect = 1e-59
Identities = 107/187 (57%), Positives = 139/187 (74%)
Frame = +2
Query: 95 TSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPL 274
TS SG L+ P NKG+AFT EER + GLLPP V +QE Q++ ++ +Y+ PL
Sbjct: 92 TSVASGYTLLRDPHHNKGLAFTEEERDGHYLRGLLPPAVLSQELQIKKFMNTLRQYQTPL 151
Query: 275 NKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHD 454
+YI +M L + +E LFY+ + DNV E++P VYTPTVG ACQK+G ++ RP+GL++++ D
Sbjct: 152 QRYIAMMNLQETDERLFYKLLIDNVVELLPFVYTPTVGEACQKYGSIFGRPQGLYVSLKD 211
Query: 455 KGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCL 634
KG V +VL+NWP +++ I VTDGERILGLGDLG GMGIPVGKLALYTALGG+ P CL
Sbjct: 212 KGKVLEVLRNWPHRNIQVICVTDGERILGLGDLGCQGMGIPVGKLALYTALGGVDPSVCL 271
Query: 635 PITIDVG 655
PITIDVG
Sbjct: 272 PITIDVG 278
>UniRef50_Q4S0L0 Cluster: Malic enzyme; n=2; Tetraodon
nigroviridis|Rep: Malic enzyme - Tetraodon nigroviridis
(Green puffer)
Length = 694
Score = 229 bits (559), Expect = 6e-59
Identities = 106/173 (61%), Positives = 132/173 (76%)
Frame = +2
Query: 77 SGDGQPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSID 256
+ +G + G D ++P LNKGMAFT+EER +GIHGLLPP +Q+ QV S +
Sbjct: 51 ASEGSVRTKKRGYDITRNPHLNKGMAFTLEERLQMGIHGLLPPCFLSQDVQVLRVMKSYE 110
Query: 257 RYENPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGL 436
NPL+KYI LM L DRNE LFYR + ++ + MPIVYTPTVGLACQ++GL +RRPRGL
Sbjct: 111 TRSNPLDKYILLMTLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYGLAFRRPRGL 170
Query: 437 FITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLAL 595
FITIHD+GH+ +L +WPE D++A+VVTDGERILGLGDLG+ GMGIPVGKLAL
Sbjct: 171 FITIHDRGHIATMLNSWPEEDIKAVVVTDGERILGLGDLGSYGMGIPVGKLAL 223
>UniRef50_Q89G76 Cluster: Malic enzyme; n=3; cellular organisms|Rep:
Malic enzyme - Bradyrhizobium japonicum
Length = 531
Score = 225 bits (549), Expect = 1e-57
Identities = 106/178 (59%), Positives = 130/178 (73%)
Frame = +2
Query: 122 LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGL 301
L+ P LNKG AFT ER LG+ GLLPP V T E QV+ ++ L KY+ L L
Sbjct: 4 LRDPLLNKGTAFTEAERAALGLRGLLPPCVLTMETQVDRVLTNLRMLPTDLEKYVALNAL 63
Query: 302 LDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLK 481
DRNE LF+R V DN+ E+ PI+YTPTVGLACQK+GL+++RPRG+FI+ D+G + ++LK
Sbjct: 64 HDRNEALFFRVVVDNIDEIQPIIYTPTVGLACQKYGLIFQRPRGMFISSRDRGQIAEILK 123
Query: 482 NWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVG 655
NWP R IVVTDGERILGLGDLGA GMGIPVGKL+LY+A G+ P CLPI +DVG
Sbjct: 124 NWP-YPARLIVVTDGERILGLGDLGANGMGIPVGKLSLYSACAGVHPEHCLPIVLDVG 180
>UniRef50_A7CWP9 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=1;
Opitutaceae bacterium TAV2|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Opitutaceae
bacterium TAV2
Length = 561
Score = 220 bits (538), Expect = 2e-56
Identities = 106/203 (52%), Positives = 138/203 (67%)
Frame = +2
Query: 56 DRIGLWGSGDGQPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVE 235
D++ G + L G L LNKG AF+ ER LG+ GLLPPRV T E+Q +
Sbjct: 6 DQVSSLGLSARGARASLRGTALLGDSVLNKGTAFSERERDALGLRGLLPPRVFTLEQQEQ 65
Query: 236 LCKLSIDRYENPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLV 415
++ + + + KYIYL L RNE LFYR + ++ EM+P+VYTPTVG AC ++G
Sbjct: 66 RALNAMAKKPSAIEKYIYLTTLQSRNETLFYRLLTNHAEEMIPLVYTPTVGQACLEYGAN 125
Query: 416 YRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLAL 595
+RRPRGLFI+I D+G + ++L++WP TDVR IVVTDGERILGLGDLG GMGIPVGKLAL
Sbjct: 126 FRRPRGLFISIKDRGRIAEILRHWPITDVRMIVVTDGERILGLGDLGVLGMGIPVGKLAL 185
Query: 596 YTALGGIKPHQCLPITIDVGYEH 664
Y+A G+ P CLPI +D G ++
Sbjct: 186 YSACAGLHPSYCLPIALDAGIDN 208
>UniRef50_A7PC00 Cluster: Chromosome chr2 scaffold_11, whole genome
shotgun sequence; n=3; Vitis vinifera|Rep: Chromosome
chr2 scaffold_11, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 573
Score = 217 bits (529), Expect = 3e-55
Identities = 100/183 (54%), Positives = 132/183 (72%)
Frame = +2
Query: 107 SGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYI 286
SG L+ P NKG+AFT +ER + GLLPP V Q+ Q + ++ +Y+ PL +Y+
Sbjct: 196 SGYTLLRDPHHNKGLAFTEKERDAHYLRGLLPPAVLNQDLQEKRLMHNLRQYKVPLQRYM 255
Query: 287 YLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHV 466
+M +RNE LFY+ + DNV E++P+VYTPTVG ACQK+G ++RRP+ L+I G +
Sbjct: 256 AMMDFQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRRPQSLYIIDFFMGKI 315
Query: 467 YDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITI 646
+VLKNWPE ++ IVVT+GERILGLGDLG GMGIPVGKL+LYT LGG+ P CLP+TI
Sbjct: 316 LEVLKNWPERSIQVIVVTNGERILGLGDLGCQGMGIPVGKLSLYTTLGGLHPSVCLPVTI 375
Query: 647 DVG 655
DVG
Sbjct: 376 DVG 378
>UniRef50_Q5BX10 Cluster: Malic enzyme; n=1; Schistosoma
japonicum|Rep: Malic enzyme - Schistosoma japonicum
(Blood fluke)
Length = 216
Score = 215 bits (526), Expect = 6e-55
Identities = 97/160 (60%), Positives = 123/160 (76%)
Frame = +2
Query: 104 LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKY 283
L G+D ++ P N+G AFT+ ERQLLGIHGLLPP V T E+QV ++ + L +Y
Sbjct: 52 LLGIDVVRDPRTNRGTAFTVNERQLLGIHGLLPPSVLTLEQQVSKMLANLKNMNDNLQRY 111
Query: 284 IYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGH 463
IYL L DRNE LFY+ V ++V MP++YTPTVGLACQ++G+V+RRPRGL+ITIHD+ H
Sbjct: 112 IYLTSLQDRNEALFYKLVIEHVEYCMPLIYTPTVGLACQRYGVVFRRPRGLYITIHDRHH 171
Query: 464 VYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVG 583
+ ++L NWPE V+AIV TDGERILGLGDLGA GMGIP+G
Sbjct: 172 IPEILNNWPEPIVKAIVFTDGERILGLGDLGAYGMGIPIG 211
>UniRef50_P78715 Cluster: Malic enzyme, hydrogenosomal precursor;
n=1; Neocallimastix frontalis|Rep: Malic enzyme,
hydrogenosomal precursor - Neocallimastix frontalis
(Rumen fungus)
Length = 592
Score = 211 bits (515), Expect = 1e-53
Identities = 97/183 (53%), Positives = 126/183 (68%)
Frame = +2
Query: 107 SGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYI 286
+GLD L P LNKG AFT +E+ LGI GL+PPR ++ E Q + CK ++D+ +PL K+I
Sbjct: 46 TGLDILNDPKLNKGSAFTADEKDRLGIRGLVPPRPQSLEAQYKRCKTNLDKISDPLEKFI 105
Query: 287 YLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHV 466
YL L +RNE L+Y+ + +N E+ PI+YTP VG ACQKF ++ + RG++ + D+G +
Sbjct: 106 YLNHLQNRNETLYYKMILENFVELAPIIYTPVVGEACQKFHKIFTQTRGMYFSTADRGQM 165
Query: 467 YDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITI 646
V NWP DV IVVTDG RILGLGDLGA GM IP+GKL LY GGI P LPI +
Sbjct: 166 SAVAANWPYDDVDVIVVTDGSRILGLGDLGAGGMQIPIGKLTLYVCGGGINPRNVLPIVL 225
Query: 647 DVG 655
DVG
Sbjct: 226 DVG 228
>UniRef50_Q0AIF8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Nitrosomonas|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Nitrosomonas
eutropha (strain C71)
Length = 536
Score = 207 bits (506), Expect = 2e-52
Identities = 97/184 (52%), Positives = 128/184 (69%)
Frame = +2
Query: 104 LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKY 283
L G L P NK AFT EER+ G+ GLLP V ++Q + ++ + + KY
Sbjct: 4 LYGKTLLNDPVQNKSTAFTREEREHYGLQGLLPYGVTDIKKQQQRVLANLRNKSSNIEKY 63
Query: 284 IYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGH 463
IYL LL+RN+ LFYR + D++ E+MP+VYTPTVG AC K ++R+P+G +IT D+G
Sbjct: 64 IYLNDLLERNQQLFYRTLVDHIGEIMPLVYTPTVGEACVKLSHIFRKPQGFYITPEDRGE 123
Query: 464 VYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPIT 643
+ LKNWPETDV+ IVVTDGERILGLGDLGA GMGIP+GK++LY A GI P +C+P+
Sbjct: 124 IISRLKNWPETDVQIIVVTDGERILGLGDLGANGMGIPIGKISLYVACAGIYPDRCMPVM 183
Query: 644 IDVG 655
+DVG
Sbjct: 184 LDVG 187
>UniRef50_Q8D911 Cluster: NAD-dependent malic enzyme; n=187;
cellular organisms|Rep: NAD-dependent malic enzyme -
Vibrio vulnificus
Length = 562
Score = 203 bits (496), Expect = 3e-51
Identities = 96/182 (52%), Positives = 125/182 (68%)
Frame = +2
Query: 122 LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGL 301
L P LNKG AF+ EER + GLLP +T +EQVE + +E+ ++K+IYL +
Sbjct: 18 LSTPLLNKGSAFSAEERISFNLEGLLPETTETIQEQVERAYMQYKAFESDMDKHIYLRNI 77
Query: 302 LDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLK 481
D NE LFYR V +++ EMMPI+YTPTVG AC+ F +YRR RGLF++ ++ + D+L
Sbjct: 78 QDTNETLFYRLVQNHITEMMPIIYTPTVGAACENFSNIYRRGRGLFVSYANRDRIDDILN 137
Query: 482 NWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGYE 661
N +V+ IVVTDGERILGLGD G GMGIP+GKL+LYTA GGI P LPI +DVG
Sbjct: 138 NASNHNVKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPIVLDVGTN 197
Query: 662 HP 667
+P
Sbjct: 198 NP 199
>UniRef50_A7IMB8 Cluster: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=2;
Alphaproteobacteria|Rep: Malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)) - Xanthobacter
sp. (strain Py2)
Length = 550
Score = 199 bits (485), Expect = 6e-50
Identities = 94/188 (50%), Positives = 128/188 (68%)
Frame = +2
Query: 92 PTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENP 271
P S LSGL+ L P NKG A+T ++R+ LG+ GLLP V+T + QVE +D ++
Sbjct: 13 PKSNLSGLNLLHDPVRNKGTAYTRDDRRQLGLEGLLPHAVETLDRQVERVLDHLDHVKDE 72
Query: 272 LNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIH 451
L++Y YLM L RNE +FY+ V + +PI+Y PTV AC+ FG +YRRPRG++IT H
Sbjct: 73 LDQYSYLMDLEARNETVFYKAVMSDPKRFIPILYDPTVADACEAFGNLYRRPRGMYITRH 132
Query: 452 DKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQC 631
KG + +VL+NWP+ D+R + V+ G RILGLGD+GA GMGIP+GKL LYTA + P
Sbjct: 133 MKGRMAEVLRNWPQKDIRFVCVSTGGRILGLGDIGANGMGIPIGKLQLYTACAAVPPDVL 192
Query: 632 LPITIDVG 655
LP+ D+G
Sbjct: 193 LPVLFDIG 200
>UniRef50_Q86NT5 Cluster: Malic enzyme; n=2; Drosophila
melanogaster|Rep: Malic enzyme - Drosophila melanogaster
(Fruit fly)
Length = 610
Score = 197 bits (480), Expect = 2e-49
Identities = 93/173 (53%), Positives = 123/173 (71%), Gaps = 1/173 (0%)
Frame = +2
Query: 140 NKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEH 319
NK +AFT+EERQ L IHGL+P V+T +EQ+ + + +E+ + +Y YL L E
Sbjct: 56 NKALAFTLEERQRLCIHGLMPACVRTYDEQMLAIESNFHSFESNVGRYRYLRALRQGYER 115
Query: 320 LFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWP-ET 496
L+++FV+ NV ++PI+YTPTVGLAC +G++YR G+ IT HD+GH+ +L NWP
Sbjct: 116 LYFQFVSKNVHAVLPIIYTPTVGLACTVYGMLYRGMTGIHITKHDRGHMKQILSNWPMRR 175
Query: 497 DVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVG 655
V+AI VTDG+RILGLGDLGA GMGI VGK+ LYTAL GI P LPI +DVG
Sbjct: 176 SVKAICVTDGQRILGLGDLGANGMGIAVGKMELYTALAGIPPSMLLPICLDVG 228
>UniRef50_Q875H8 Cluster: Malic enzyme; n=1; Mucor
circinelloides|Rep: Malic enzyme - Mucor circinelloides
Length = 617
Score = 194 bits (472), Expect = 2e-48
Identities = 89/182 (48%), Positives = 126/182 (69%)
Frame = +2
Query: 110 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIY 289
G++ L P L+KG AF+I ER+ L I GL+PPR + ++Q+ K ++D E PL K+++
Sbjct: 50 GVNLLHDPLLSKGTAFSIAERERLSIRGLVPPRCQEMDKQLLRIKRNLDACETPLAKFVF 109
Query: 290 LMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVY 469
L L DRNE L+Y+ + +++ E+ I+YTPTVGLA Q +YRR RG++ + D+G +
Sbjct: 110 LAALHDRNETLYYKIIMEHLEELAGIIYTPTVGLASQMSHSIYRRSRGMYFSSQDRGQMS 169
Query: 470 DVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 649
++ NWP V IVVTDG R+LGLGDLGA GM IP+GKL+LY A GGI+P LP+ +D
Sbjct: 170 AMVYNWPHDKVDVIVVTDGSRVLGLGDLGANGMEIPIGKLSLYVAAGGIRPRAVLPVVLD 229
Query: 650 VG 655
VG
Sbjct: 230 VG 231
>UniRef50_Q016K2 Cluster: NADP dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP dependent malic enzyme -
Ostreococcus tauri
Length = 641
Score = 189 bits (461), Expect = 5e-47
Identities = 88/187 (47%), Positives = 128/187 (68%)
Frame = +2
Query: 104 LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKY 283
+SG++ L+ NKGM+F +ER L + GLLPP V Q QVE + R + + K+
Sbjct: 81 ISGVELLRSGRYNKGMSFARDERDRLNLRGLLPPAVFDQATQVERVIERLRRVTSGVEKH 140
Query: 284 IYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGH 463
+L L +RNE LFYR V D++ E++P++ PTV C++ GL+YR+PRGL++++ DKG
Sbjct: 141 AWLPALYERNERLFYRVVKDHLEELLPVLAEPTVWQVCREAGLMYRQPRGLYVSMQDKGS 200
Query: 464 VYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPIT 643
VY +LKNWP +V+A+V+TDG+R+ G+GDLG GM V K +L+TALGG+ P LPI
Sbjct: 201 VYRLLKNWPVRNVKAVVLTDGQRVTGIGDLGVQGMPAAVSKASLFTALGGLDPADVLPIC 260
Query: 644 IDVGYEH 664
IDVG ++
Sbjct: 261 IDVGTDN 267
>UniRef50_Q8I8I4 Cluster: Malic enzyme; n=4; Eukaryota|Rep: Malic
enzyme - Mastigamoeba balamuthi (Phreatamoeba balamuthi)
Length = 568
Score = 187 bits (456), Expect = 2e-46
Identities = 97/189 (51%), Positives = 119/189 (62%)
Frame = +2
Query: 89 QPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYEN 268
+P GL+G L G AFT EER+ L I GLLP V+T E Q +
Sbjct: 30 RPADGLAGPSWLTLAPT--GTAFTTEERKALRIRGLLPHAVETIEAQAARAYAQLTSQPT 87
Query: 269 PLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITI 448
PL KY+YL L RN+ LF+ V +V E +P+VYTPTVG C KF +R P GL+IT
Sbjct: 88 PLLKYLYLSQLSQRNQTLFFYLVQHHVEECVPLVYTPTVGEGCTKFSAEFRNPTGLYITP 147
Query: 449 HDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQ 628
DKGHV ++L+NWP +V IVVTDG RILGLGDLG+ GMGIP+GKL LY A G +P +
Sbjct: 148 EDKGHVAEILENWPH-EVEIIVVTDGGRILGLGDLGSNGMGIPIGKLHLYIACAGFRPDR 206
Query: 629 CLPITIDVG 655
LP+ IDVG
Sbjct: 207 TLPVMIDVG 215
>UniRef50_P37221 Cluster: NAD-dependent malic enzyme 62 kDa isoform,
mitochondrial precursor; n=41; Eukaryota|Rep:
NAD-dependent malic enzyme 62 kDa isoform, mitochondrial
precursor - Solanum tuberosum (Potato)
Length = 626
Score = 183 bits (446), Expect = 3e-45
Identities = 92/194 (47%), Positives = 123/194 (63%), Gaps = 10/194 (5%)
Frame = +2
Query: 113 LDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQV-----ELCKLSIDRYENPLN 277
LD L P NKG AF+ ER L I GLLPP V + E+Q+ +L +L + + P +
Sbjct: 50 LDILHDPWFNKGTAFSFTERDRLHIRGLLPPNVMSFEQQIARFMADLKRLEVQARDGPSD 109
Query: 278 KYIY-----LMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFI 442
Y+ L L DRNE L+Y+ + +N+ E PIVYTPTVGL CQK+ ++RRPRG++
Sbjct: 110 PYVLAKWRILNRLHDRNETLYYKVLMENIEEYAPIVYTPTVGLVCQKYSGLFRRPRGMYF 169
Query: 443 TIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKP 622
+ D+G + ++ NWP V IVVTDG RILGLGDLG G+GI +GKL LY A GI P
Sbjct: 170 SAEDRGEMMSMVYNWPADQVDMIVVTDGSRILGLGDLGIQGIGIAIGKLDLYVAAAGINP 229
Query: 623 HQCLPITIDVGYEH 664
+ LP+ IDVG ++
Sbjct: 230 QRVLPVMIDVGTDN 243
>UniRef50_A1ZAF7 Cluster: Malic enzyme; n=5; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 603
Score = 182 bits (444), Expect = 5e-45
Identities = 81/175 (46%), Positives = 121/175 (69%)
Frame = +2
Query: 140 NKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEH 319
NKG+AFTI+ERQ LGI GL+P V++ ++Q+ + + + ++ YL + R+
Sbjct: 48 NKGLAFTIKERQRLGIMGLMPCSVRSMDDQMNAALANFEARPTDIARFTYLSAVHHRHRR 107
Query: 320 LFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETD 499
L+YRF+ +N+ + +PIVYTPTVG +GL +++ LFI+IHDKGH+ D++ NW +
Sbjct: 108 LYYRFIKENIEKSLPIVYTPTVGDVVATYGLNFQQAISLFISIHDKGHIRDLMHNWVDEG 167
Query: 500 VRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGYEH 664
V+AI VTDG R+LGLGD+GA MGI +GK+ LYTALG I P +P+ +DVG ++
Sbjct: 168 VKAICVTDGGRVLGLGDMGANAMGISLGKMILYTALGSIPPSTLMPVCLDVGTDN 222
>UniRef50_A6SA55 Cluster: Malic enzyme; n=2; Sclerotiniaceae|Rep:
Malic enzyme - Botryotinia fuckeliana B05.10
Length = 685
Score = 182 bits (442), Expect = 9e-45
Identities = 83/176 (47%), Positives = 121/176 (68%)
Frame = +2
Query: 128 HPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLD 307
HP L + +IE R+ GL+PP V++ + Q C ++ + P+ KY+YL L +
Sbjct: 97 HPIL-PDTSHSIELRRKNKTLGLVPPNVESHKLQTTRCLQQLNAKKTPIEKYMYLSNLRN 155
Query: 308 RNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNW 487
N HLFYR V +++ ++ P++YTPTVG AC ++ +Y++P GL+++ HD+G++ +VL NW
Sbjct: 156 NNVHLFYRLVQEHLTDITPLIYTPTVGEACLRWSEIYQQPEGLYLSYHDRGNLEEVLGNW 215
Query: 488 PETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVG 655
++DV VVTDG RILGLGDLG GMGIPVGKL+LYT GI P + LPIT+D+G
Sbjct: 216 RQSDVEMTVVTDGSRILGLGDLGVNGMGIPVGKLSLYTGCAGIHPSKTLPITLDLG 271
>UniRef50_A2EKE3 Cluster: Malic enzyme; n=14; Trichomonadidae|Rep:
Malic enzyme - Trichomonas vaginalis G3
Length = 567
Score = 181 bits (440), Expect = 2e-44
Identities = 89/184 (48%), Positives = 120/184 (65%), Gaps = 1/184 (0%)
Frame = +2
Query: 107 SGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYI 286
+G+ L+ LNKG AFT EER + GLLP +V T++EQ + + PL KYI
Sbjct: 23 TGMTLLQDGDLNKGTAFTKEERDRFNLRGLLPYKVFTKDEQAARIRRQFELMPTPLLKYI 82
Query: 287 YLMGLLDRNEHLFYRFVADNVAE-MMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGH 463
+L ++N F+RF+ + E MPI+YTPTVG ACQK+ + RG++IT D G
Sbjct: 83 FLANEREKNSQSFWRFLFTHPPEETMPILYTPTVGEACQKWATHRQSYRGIYITPEDSGK 142
Query: 464 VYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPIT 643
+ D+L+N+P D+R IVVTD RILGLGDLGA G+GIPVGKL LYT +G + P Q LP+
Sbjct: 143 IKDILRNYPRQDIRCIVVTDAGRILGLGDLGASGLGIPVGKLMLYTLIGQVDPDQTLPVQ 202
Query: 644 IDVG 655
+D+G
Sbjct: 203 LDMG 206
>UniRef50_Q4QAQ6 Cluster: Malic enzyme, putative; n=20;
Trypanosomatidae|Rep: Malic enzyme, putative -
Leishmania major
Length = 573
Score = 180 bits (439), Expect = 2e-44
Identities = 81/182 (44%), Positives = 125/182 (68%)
Frame = +2
Query: 110 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIY 289
G+D+L++ NKG AFT ER + + GLLPP V+T ++QVE ++R+ P+N+Y
Sbjct: 19 GVDYLRNRFTNKGTAFTAAERSHMNVEGLLPPSVETLDDQVERYWDQLNRFNEPINRYQL 78
Query: 290 LMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVY 469
L + + N L+Y + + + +PIVYTPTVG ACQ++G +Y++ GL++ + KG V
Sbjct: 79 LRNVQNTNVTLYYAILTRYLKQTLPIVYTPTVGEACQRYGDLYQKDHGLYLDVASKGKVR 138
Query: 470 DVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 649
+++N +T++ IV+TDG RILGLGDLG+ G+GI +GK +LY A GG+KP + LP+ +D
Sbjct: 139 RLIQNLRKTNIDVIVITDGSRILGLGDLGSNGIGISIGKCSLYVAAGGVKPSRVLPVVMD 198
Query: 650 VG 655
VG
Sbjct: 199 VG 200
>UniRef50_Q00XN9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus tauri
Length = 639
Score = 178 bits (434), Expect = 9e-44
Identities = 87/182 (47%), Positives = 115/182 (63%)
Frame = +2
Query: 110 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIY 289
G++ L +P NKG +FT ER+ LG+ GL+PPR +Q E PL+K+ +
Sbjct: 81 GIEVLHNPVYNKGTSFTASERERLGVRGLVPPRFFPIGQQATKIWAQNQSLERPLDKWQH 140
Query: 290 LMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVY 469
L L DRNE LFYR V D++ E+ PI+YTPTVG AC F + RR RG++ ++ D+G +
Sbjct: 141 LQDLKDRNETLFYRLVHDHIEELAPIIYTPTVGDACLNFSKLLRRARGMYFSVDDRGDIN 200
Query: 470 DVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 649
++ NW + V IVVTDG RILGLGDLG GMGI GK+ LY A GG P LP+ +D
Sbjct: 201 SMMFNW-KRSVSVIVVTDGSRILGLGDLGTNGMGISQGKVDLYVAGGGFDPQHVLPVVLD 259
Query: 650 VG 655
VG
Sbjct: 260 VG 261
>UniRef50_UPI0000D9F768 Cluster: PREDICTED: similar to Y48B6A.12,
partial; n=1; Macaca mulatta|Rep: PREDICTED: similar to
Y48B6A.12, partial - Macaca mulatta
Length = 456
Score = 177 bits (432), Expect = 1e-43
Identities = 83/159 (52%), Positives = 108/159 (67%)
Frame = +2
Query: 191 GLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIV 370
GLLPP+V + Q C L + N + KYIYL L DRNE L+++ + D+VAEMMPIV
Sbjct: 34 GLLPPKVLDLDVQSRRCYLQFSQNSNDIEKYIYLESLHDRNETLYFKLLVDHVAEMMPIV 93
Query: 371 YTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGD 550
YTP VG ACQ FG ++R RGL+ + +KG+ +++ N D IVVTDG RILGLGD
Sbjct: 94 YTPVVGKACQLFGHIFRNARGLYFNLSEKGNFKEMVWNSNVRDADIIVVTDGSRILGLGD 153
Query: 551 LGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGYEHP 667
LG GMGIP+GKL+LY A GI P + +P+T+DVG +P
Sbjct: 154 LGTNGMGIPIGKLSLYVACAGINPGRTVPVTLDVGTNNP 192
>UniRef50_A1SVL3 Cluster: Malic enzyme aka malate dehydrogenase
(Oxaloacetate-decarboxylating) (NADP(+)); n=4;
Gammaproteobacteria|Rep: Malic enzyme aka malate
dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)) -
Psychromonas ingrahamii (strain 37)
Length = 571
Score = 176 bits (429), Expect = 3e-43
Identities = 88/201 (43%), Positives = 126/201 (62%), Gaps = 3/201 (1%)
Frame = +2
Query: 71 WGSGDG---QPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELC 241
W +G +P S L+G + L + LNK AFT +ER+ ++GLLPPRV+T E+Q++
Sbjct: 9 WEDSEGNVFRPVS-LTGNELLNNRTLNKSTAFTYQEREDFDLNGLLPPRVQTFEDQLKRV 67
Query: 242 KLSIDRYENPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYR 421
+ KY YL L DRNE LFY ++ N+ EM PI+YTPTVG ACQ+F ++
Sbjct: 68 YQGFSASSTDIEKYQYLRALQDRNETLFYALISRNIEEMTPIIYTPTVGKACQEFSHRFQ 127
Query: 422 RPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYT 601
RGL++T + V + + + D++ IVVTD + ILG+GD G GMGIP+GKL+LYT
Sbjct: 128 IARGLYLTTDNIHDVGSMAREFTGKDIQIIVVTDSQGILGIGDQGVGGMGIPIGKLSLYT 187
Query: 602 ALGGIKPHQCLPITIDVGYEH 664
GI P C+PI +D+G ++
Sbjct: 188 LGAGIHPDHCMPIALDIGTDN 208
>UniRef50_Q4X1Z2 Cluster: NADP-dependent malic enzyme MaeA; n=11;
Pezizomycotina|Rep: NADP-dependent malic enzyme MaeA -
Aspergillus fumigatus (Sartorya fumigata)
Length = 661
Score = 176 bits (428), Expect = 5e-43
Identities = 76/162 (46%), Positives = 111/162 (68%)
Frame = +2
Query: 170 RQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFYRFVADNV 349
R+ L +GL PPR ++ E Q C + + ++K++YL L N HLFYR V D++
Sbjct: 102 RKYLRTYGLTPPRAESYEIQKTRCLAQLALKQTAIDKFLYLSTLRKNNVHLFYRLVTDHL 161
Query: 350 AEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGE 529
E+ P++YTP VG ACQK+ +Y++P G++++ D+G++ V+ NWP+ +V +TDG
Sbjct: 162 KELTPLIYTPVVGEACQKWSEIYQQPEGMYLSWEDRGNLAAVIANWPQPNVEITCITDGS 221
Query: 530 RILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVG 655
RILGLGDLG GMGIP+GKLALYTA GI+P LP+T+D+G
Sbjct: 222 RILGLGDLGINGMGIPIGKLALYTACAGIRPEATLPLTLDLG 263
>UniRef50_A4RQC9 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 549
Score = 175 bits (425), Expect = 1e-42
Identities = 82/178 (46%), Positives = 115/178 (64%)
Frame = +2
Query: 122 LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGL 301
L P LNKG FT +R+ LG+ GLLP + +T E QV+ + +E +N+YI+L L
Sbjct: 13 LDSPSLNKGTGFTFTQRERLGLRGLLPRKYETVEIQVKRAWTQLCAFEEDMNRYIFLENL 72
Query: 302 LDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLK 481
+NE LFYR + +++ ++MPIVYTPTVG AC F +YR G++ + D G + +L
Sbjct: 73 HMQNERLFYRVLVEHLEDLMPIVYTPTVGEACINFDALYRNRCGMYFSRLDSGVMRRMLD 132
Query: 482 NWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVG 655
NWP + IVVTDG R+LGLGDLG GM I VGK++LY A GG P + +P+ +D+G
Sbjct: 133 NWPSPETEIIVVTDGGRVLGLGDLGTNGMAISVGKVSLYVASGGFDPAKSMPVCLDLG 190
>UniRef50_Q9HE50 Cluster: Malic enzyme; n=6; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 1023
Score = 169 bits (412), Expect = 4e-41
Identities = 79/171 (46%), Positives = 109/171 (63%)
Frame = +2
Query: 143 KGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHL 322
KG +FT EER + GL+P ++ E+QVE I + +++Y+YL + +N L
Sbjct: 483 KGTSFTPEERVAKNLTGLIPHVMEDSEKQVERALKMIRTRQTDIDRYLYLSTIKSQNVDL 542
Query: 323 FYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDV 502
FYR + D+ EMMP+VYTPT+G C ++ +Y RP L+I+I + + +L+NWP
Sbjct: 543 FYRLLMDHAKEMMPLVYTPTIGDVCLQYSTLYTRPEALYISIKQRKSIRTILRNWPYPQP 602
Query: 503 RAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVG 655
VVTDG RILGLGDLG G+GIP+GKLALYTA GI P + LPI +D G
Sbjct: 603 EICVVTDGSRILGLGDLGVNGVGIPIGKLALYTAAAGIHPDKTLPIVLDCG 653
>UniRef50_Q9RYN4 Cluster: Malate oxidoreductase; n=6;
Deinococci|Rep: Malate oxidoreductase - Deinococcus
radiodurans
Length = 580
Score = 169 bits (410), Expect = 7e-41
Identities = 86/182 (47%), Positives = 111/182 (60%)
Frame = +2
Query: 110 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIY 289
G + + P LNKG AFT EER+ G+ GLL P+V + E +E + L K++Y
Sbjct: 37 GFNLTRIPLLNKGTAFTAEEREAHGLDGLLAPQVDSLEVLIERAYREFSKRGAALEKHVY 96
Query: 290 LMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVY 469
L L DRNE LFY ++ +V EM+PIVYTPTVG A +KF +YR PRGL ++
Sbjct: 97 LRNLQDRNEVLFYALLSHHVEEMLPIVYTPTVGDAVKKFSQIYRYPRGLTLSTRTIERAE 156
Query: 470 DVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 649
L N P DVR IV TD ILG+GD G GM I +GKL+LYT GG+ P + LP+ +D
Sbjct: 157 QALANVPLNDVRIIVATDSSAILGIGDQGFGGMAISIGKLSLYTVAGGVGPDKTLPVELD 216
Query: 650 VG 655
VG
Sbjct: 217 VG 218
>UniRef50_P45868 Cluster: Probable NAD-dependent malic enzyme 2;
n=37; Bacteria|Rep: Probable NAD-dependent malic enzyme
2 - Bacillus subtilis
Length = 582
Score = 167 bits (406), Expect = 2e-40
Identities = 82/193 (42%), Positives = 123/193 (63%), Gaps = 2/193 (1%)
Frame = +2
Query: 83 DGQPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRY 262
+G + L G + L P LNKG+AF++EERQ LG+ GLLPP V + ++Q +
Sbjct: 26 EGHLETTLRGKEVLSIPTLNKGVAFSLEERQELGLEGLLPPTVLSLDQQAQRAYEQFQAQ 85
Query: 263 ENPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFI 442
+ L + +YL L +RNE LFY+ + +++ EM+P+VYTPTVG A Q++ YRRP+G+++
Sbjct: 86 PDRLRQNVYLSDLANRNEVLFYKLLKNHLREMLPVVYTPTVGEAIQEYSHEYRRPQGIYL 145
Query: 443 TIHDKGHVYDVLKNWPET--DVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGI 616
+I + + +N T D+ IV TD E ILG+GD G G+ I +GKLA+YTA GI
Sbjct: 146 SIDNIDGIEKAFENLHATAGDIDLIVATDSESILGIGDWGVGGINIAIGKLAVYTAAAGI 205
Query: 617 KPHQCLPITIDVG 655
P + +P+ +DVG
Sbjct: 206 DPSRVIPVVLDVG 218
>UniRef50_A3QW96 Cluster: Malic enzyme; n=10; Tigriopus
californicus|Rep: Malic enzyme - Tigriopus californicus
(Marine copepod)
Length = 322
Score = 165 bits (401), Expect = 9e-40
Identities = 84/201 (41%), Positives = 118/201 (58%), Gaps = 19/201 (9%)
Frame = +2
Query: 110 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDR------YENP 271
G + + P NKG+AF + ER L + GL+PPR+ + +EQ + R + P
Sbjct: 45 GRNLVSDPISNKGLAFPLSERDRLSVRGLVPPRILSIQEQERVIMDEYTRGWAARAEQEP 104
Query: 272 -------------LNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGL 412
+ K+ L + DRNE LFYR + DN +M PI+YTPTVG AC F
Sbjct: 105 EDEIIKSGVGPDNIRKWKVLQSVQDRNETLFYRILMDNFQDMAPIIYTPTVGWACSHFSQ 164
Query: 413 VYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLA 592
+YRRPRG++ + D+G + ++ NW +V A+V+TDG RILGLGDLG G+GI +GKL
Sbjct: 165 LYRRPRGMYFSHGDRGEMASMVYNWESDEVDAVVITDGSRILGLGDLGLGGLGISIGKLD 224
Query: 593 LYTALGGIKPHQCLPITIDVG 655
LY A GG P + LP+ +D+G
Sbjct: 225 LYVAAGGFHPRRVLPVVLDIG 245
>UniRef50_Q4PC56 Cluster: Malic enzyme; n=1; Ustilago maydis|Rep:
Malic enzyme - Ustilago maydis (Smut fungus)
Length = 634
Score = 165 bits (400), Expect = 1e-39
Identities = 82/184 (44%), Positives = 110/184 (59%), Gaps = 4/184 (2%)
Frame = +2
Query: 116 DH--LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIY 289
DH + P N+ F+ E+R LG+ GLLPP ++ QV + PL K++
Sbjct: 77 DHRIISDPFPNQDTGFSYEKRDQLGLRGLLPPAKQSLNTQVLRVLHQLRSKSTPLEKHVM 136
Query: 290 LMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVY 469
L L N L+Y + N E++P++YTPTVG ACQKF +YRRP GL I++ DKG +
Sbjct: 137 LASLRQTNTRLYYATILANKEEILPLIYTPTVGEACQKFSHIYRRPEGLSISLEDKGKIA 196
Query: 470 DVLKNW--PETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPIT 643
+++NW P R V+TDG RILGLGDLG G GI +GKL+LY A GI P LPI
Sbjct: 197 SIVENWPVPAGSPRIAVITDGSRILGLGDLGWNGQGISIGKLSLYVAGAGIHPRATLPIV 256
Query: 644 IDVG 655
+D+G
Sbjct: 257 VDLG 260
>UniRef50_A0Q531 Cluster: NAD-dependent malic enzyme; n=10;
Francisella tularensis|Rep: NAD-dependent malic enzyme -
Francisella tularensis subsp. novicida (strain U112)
Length = 604
Score = 163 bits (395), Expect = 5e-39
Identities = 79/186 (42%), Positives = 116/186 (62%)
Frame = +2
Query: 98 SGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLN 277
+ L+G L + LNK +AF+ EER + G LP +V++ EEQ + +D N L
Sbjct: 23 TNLTGRQLLNNRVLNKDVAFSQEERIAFDLIGYLPEKVESLEEQAIRVRRQLDLKPNSLE 82
Query: 278 KYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 457
KY++L L D N LFY FV +N+ E+MPI+YTPTVG A QK+ +R+ GLFI+I K
Sbjct: 83 KYVFLNRLHDLNTTLFYHFVRENLEEIMPIIYTPTVGEAVQKYSSSFRKQSGLFISISHK 142
Query: 458 GHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLP 637
H+ +L+ + + ++VTDGE +LG+GD G GM I +GK+ +Y A GI P + LP
Sbjct: 143 KHIARILERYEYNSIDLVLVTDGEAVLGIGDQGIGGMNISIGKIMVYVAASGIDPARVLP 202
Query: 638 ITIDVG 655
+ +D+G
Sbjct: 203 VQLDMG 208
>UniRef50_Q5CS07 Cluster: Malic enzyme; n=2; Cryptosporidium|Rep:
Malic enzyme - Cryptosporidium parvum Iowa II
Length = 614
Score = 163 bits (395), Expect = 5e-39
Identities = 80/188 (42%), Positives = 122/188 (64%), Gaps = 4/188 (2%)
Frame = +2
Query: 104 LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKY 283
L G++ L++P NKG++FT+EER+ G+ GLLP + +T +EQV +I++ ++ + KY
Sbjct: 64 LKGIELLRNPFYNKGLSFTMEERKEYGLEGLLPAKYETIDEQVSRLWTAINKIDSNIGKY 123
Query: 284 IYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGL--VYRR--PRGLFITIH 451
+L + + LF+ + ++ P+VYTPTVG C +F R GL++
Sbjct: 124 TFLENIRSSSFILFHSLLDKYFKDLTPLVYTPTVGEGCIEFSRNPTIRNWLGSGLYLNKS 183
Query: 452 DKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQC 631
KG +Y++LK++ D+ IV+TDG RILGLGDLG GMGIP+GKL+LY LGGI P +
Sbjct: 184 HKGRIYEILKDFKSDDIEIIVLTDGGRILGLGDLGLNGMGIPMGKLSLYITLGGIDPSKV 243
Query: 632 LPITIDVG 655
LPI++D+G
Sbjct: 244 LPISLDIG 251
>UniRef50_Q7SHJ8 Cluster: Malic enzyme; n=12; Pezizomycotina|Rep:
Malic enzyme - Neurospora crassa
Length = 611
Score = 162 bits (393), Expect = 8e-39
Identities = 85/195 (43%), Positives = 116/195 (59%), Gaps = 2/195 (1%)
Frame = +2
Query: 77 SGDGQPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSID 256
S G L G L HP NKG AFT EER+ +HGLLPP++++ E+QV+
Sbjct: 24 STSGPLECALKGTVLLNHPYFNKGSAFTKEERRDFALHGLLPPQIQSLEQQVQRAYEQYC 83
Query: 257 RYENPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGL 436
N L K ++ + ++NE LFYR + D++ EM +VYTPT G A Q + ++RRP G+
Sbjct: 84 SQPNDLAKNTFMTSMKEQNEVLFYRLLHDHLDEMFSVVYTPTEGEAIQNYSRLFRRPEGV 143
Query: 437 FITIHDKGHVYDVLKNW--PETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALG 610
F+ I+D V L W PE D+ IVVTDGE ILG+GD G G+ I + KL L T G
Sbjct: 144 FLNINDMDSVKRDLAQWGKPE-DIDYIVVTDGEEILGIGDQGCGGILISIAKLVLMTICG 202
Query: 611 GIKPHQCLPITIDVG 655
GI P++ LP+ +D G
Sbjct: 203 GIHPNRVLPVVLDCG 217
>UniRef50_Q01AM5 Cluster: NADP+-dependent malic enzyme; n=2;
Ostreococcus|Rep: NADP+-dependent malic enzyme -
Ostreococcus tauri
Length = 580
Score = 151 bits (367), Expect = 1e-35
Identities = 75/182 (41%), Positives = 109/182 (59%)
Frame = +2
Query: 110 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIY 289
G L+ +G+A +R+ G+ GL+P +E ++ ++ + E P KY
Sbjct: 48 GYASLRDASAYRGLA--TNDRRGKGVDGLIPAGEVGEEVEIARANAALAQCETPFEKYKQ 105
Query: 290 LMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVY 469
L+ L +E FYR + ++PI+YTPTVG AC KFG + +RP GL+++ +D G+V
Sbjct: 106 LVALQMTDESTFYRMLRSQTETLLPILYTPTVGEACVKFGTLVQRPMGLWVSSNDAGNVK 165
Query: 470 DVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITID 649
+++NWP TDV+ V+TDGERILGLGD GA GMGI GK +Y A G+ P LPI +D
Sbjct: 166 QLIRNWPATDVKIAVITDGERILGLGDQGANGMGISAGKSMVYAAC-GVPPSALLPIQVD 224
Query: 650 VG 655
G
Sbjct: 225 TG 226
>UniRef50_Q6AL43 Cluster: Related to NAD-dependent malic enzyme;
n=1; Desulfotalea psychrophila|Rep: Related to
NAD-dependent malic enzyme - Desulfotalea psychrophila
Length = 578
Score = 150 bits (363), Expect = 3e-35
Identities = 72/175 (41%), Positives = 105/175 (60%)
Frame = +2
Query: 140 NKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEH 319
NK AF+ +ER G+ G LPP + E QVE C + + E+ KYI++ L DRN
Sbjct: 35 NKSTAFSSKERDDFGLQGSLPPGFRDLEAQVENCHIKLGEKESEEEKYIFIRSLFDRNVT 94
Query: 320 LFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETD 499
L + + ++ + M I+YTPTVGLA QK+ ++R+ GL + D+L+ + D
Sbjct: 95 LAHALIQSDLEKFMGIIYTPTVGLAVQKYSAMFRQANGLHFSPDTIDQAEDILRRFAHRD 154
Query: 500 VRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGYEH 664
+R VVTD + ILG+GD GA G+ I +GKL LYT GI P CLPI++D+G ++
Sbjct: 155 IRVAVVTDNQGILGIGDQGAGGIAICLGKLMLYTQGAGIAPWHCLPISLDIGTDN 209
>UniRef50_A3BK03 Cluster: Malic enzyme; n=2; Oryza sativa|Rep: Malic
enzyme - Oryza sativa subsp. japonica (Rice)
Length = 635
Score = 149 bits (362), Expect = 5e-35
Identities = 88/216 (40%), Positives = 119/216 (55%), Gaps = 10/216 (4%)
Frame = +2
Query: 38 YSEMERDRIGLWGSGDGQPTSGLSGLDHLKHPGLNKGMAFTIEERQL------LGIHGLL 199
+S ERDR+GL G S +D P L F E + + L +
Sbjct: 60 FSMTERDRLGLRGLLPPNVVSSQQQIDRFT-PTLKYQYKFHSEIQHIDAKGLALNYLNIS 118
Query: 200 PPRVKTQEEQVELCKLSIDRYEN--PLNKYIYLMGLLDRNEHLFYR--FVADNVAEMMPI 367
P ++ + V K + D + PL K+ L L DRNE ++Y+ + DN+ E PI
Sbjct: 119 PAICESSQYCVNADKYARDGPSDTYPLAKWRILNRLHDRNETMYYKAEVLIDNIEEHAPI 178
Query: 368 VYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLG 547
VYTPTVGL CQ + ++RRPRG++ + D+G + ++ NWP V IVVTDG RILGLG
Sbjct: 179 VYTPTVGLVCQNYSGLFRRPRGMYFSAEDRGEMMSMVYNWPADQVDMIVVTDGSRILGLG 238
Query: 548 DLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVG 655
DLG G+GI +GKL LY A GI P + LP+ IDVG
Sbjct: 239 DLGVHGIGIAIGKLDLYVAAAGINPQRVLPVMIDVG 274
Score = 44.0 bits (99), Expect = 0.003
Identities = 18/42 (42%), Positives = 27/42 (64%)
Frame = +2
Query: 110 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVE 235
G D L P N+G F++ ER LG+ GLLPP V + ++Q++
Sbjct: 45 GSDILHDPWFNRGTGFSMTERDRLGLRGLLPPNVVSSQQQID 86
>UniRef50_A2QY66 Cluster: Malic enzyme; n=2; cellular organisms|Rep:
Malic enzyme - Aspergillus niger
Length = 609
Score = 148 bits (358), Expect = 1e-34
Identities = 75/186 (40%), Positives = 111/186 (59%), Gaps = 1/186 (0%)
Frame = +2
Query: 110 GLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIY 289
G D L+ NKG AFT EER+ +HGLLPP ++T EEQV+ +N L K +
Sbjct: 57 GRDALQSCQFNKGSAFTEEERKTFKLHGLLPPNIQTLEEQVQRAYEQYSSRDNDLAKNTF 116
Query: 290 LMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVY 469
+ + +NE L+Y+ + ++ EM+ I+YTPT G A Q + ++R+P G F+ I D+ +
Sbjct: 117 MASMKAQNEVLYYKLIDTHLKEMLSIIYTPTEGDAIQNYSRLFRKPEGCFLNIRDQDRIE 176
Query: 470 DVLKNWPE-TDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITI 646
+ L N+ +V IVV+DGE ILG+GD G + I V KLAL T GI P + LP+ +
Sbjct: 177 ECLSNFSRGEEVDYIVVSDGEEILGIGDQGVGAILISVAKLALTTLCAGIHPSRQLPVVL 236
Query: 647 DVGYEH 664
D G ++
Sbjct: 237 DCGTDN 242
>UniRef50_Q95061 Cluster: Malic enzyme; n=2; Giardia
intestinalis|Rep: Malic enzyme - Giardia lamblia
(Giardia intestinalis)
Length = 557
Score = 147 bits (356), Expect = 2e-34
Identities = 79/179 (44%), Positives = 102/179 (56%), Gaps = 1/179 (0%)
Frame = +2
Query: 122 LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGL 301
L++ NK AFT ER+ I LP RV+T E+Q+ C+ D P K++YL L
Sbjct: 9 LRNKDCNKDTAFTAAEREAHHIVARLPARVETIEQQISRCRAQFDVLTTPTEKWLYLTRL 68
Query: 302 LDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYR-RPRGLFITIHDKGHVYDVL 478
+ NE LF F + E++PIVYTPTVG AC + L+++ PRG ++ G V +
Sbjct: 69 QEVNETLFSGFCLKYLKEVLPIVYTPTVGTACSNYSLLWQGYPRGFYLNRTHLGKVKQIF 128
Query: 479 KNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVG 655
WP + R IV TDG RILGLGDLG G I VGKL LY+ GG P LPI+ D G
Sbjct: 129 DQWPYSP-RIIVATDGTRILGLGDLGTGGHQICVGKLTLYSLGGGFAPEHTLPISFDFG 186
>UniRef50_Q8Y5Y8 Cluster: Lmo1915 protein; n=15; Firmicutes|Rep:
Lmo1915 protein - Listeria monocytogenes
Length = 547
Score = 142 bits (345), Expect = 5e-33
Identities = 74/186 (39%), Positives = 109/186 (58%), Gaps = 3/186 (1%)
Frame = +2
Query: 107 SGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYI 286
SG D++ +P LNKG AF+ EER + GLLPP ++T E+Q + I+ E PL+K+
Sbjct: 5 SGFDYMNNPLLNKGTAFSKEERASYQLDGLLPPIIETIEQQAVRIETQIENLETPLHKHR 64
Query: 287 YLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRP-RGLFITIHDKGH 463
L L + N L+Y V NV + +PI+YTPT+G A ++ Y P LF+
Sbjct: 65 LLTNLYNENRTLYYYVVTKNVTDYLPIIYTPTIGDAVIQYHKDYTAPDEALFVDAFAPEK 124
Query: 464 VYDVLKNWPET--DVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLP 637
+ +KN+ + ++ IV+TDGE +LG+GD G+ I VGKLA+YT G+ P + LP
Sbjct: 125 LSASIKNYAKNNPNIDMIVITDGEGVLGIGDWSVNGVKIAVGKLAVYTVAAGLAPDRVLP 184
Query: 638 ITIDVG 655
+ ID G
Sbjct: 185 VVIDAG 190
>UniRef50_A6XP71 Cluster: Malic enzyme protein 2; n=2;
Mucoromycotina|Rep: Malic enzyme protein 2 - Mortierella
alpina (Mortierella renispora)
Length = 669
Score = 142 bits (345), Expect = 5e-33
Identities = 79/196 (40%), Positives = 112/196 (57%), Gaps = 16/196 (8%)
Frame = +2
Query: 116 DHL----KHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKY 283
DHL +H G A E R L + GL P +V++ E Q + + + + KY
Sbjct: 95 DHLSNTHQHTDNMTGTATPTELRSALHLQGLTPAKVESFELQKKRALAQLRSKSSDIEKY 154
Query: 284 IYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYR------RPRGLFIT 445
++L L + N LFY V D + E +P++YTPTVG ACQ + +Y +P GLF++
Sbjct: 155 VFLAWLRNTNVRLFYGLVGDQLEETLPLIYTPTVGTACQNYSSIYPFLAPPGQPDGLFLS 214
Query: 446 IHDKGHVYDVLKNW------PETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTAL 607
I+D ++ +++N+ P + V+TDG RILGLGDLG GMGIPVGKL LY A
Sbjct: 215 INDLPNLTQIIQNYKPFPQDPSLTPQIAVITDGSRILGLGDLGVGGMGIPVGKLQLYVAG 274
Query: 608 GGIKPHQCLPITIDVG 655
GI P + LPIT+D+G
Sbjct: 275 AGIDPRRTLPITLDLG 290
>UniRef50_A4SKB8 Cluster: NAD-dependent malic enzyme; n=2;
Aeromonas|Rep: NAD-dependent malic enzyme - Aeromonas
salmonicida (strain A449)
Length = 516
Score = 140 bits (339), Expect = 3e-32
Identities = 69/174 (39%), Positives = 108/174 (62%)
Frame = +2
Query: 146 GMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLF 325
G + ER+ G+ G +P + ++ +Q + ++P ++++ L L + N LF
Sbjct: 7 GTSLPYAERKRQGLMGRMPHKEESLAQQRRRIYRLVSAMQSPFDQHLLLRQLQEDNPVLF 66
Query: 326 YRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVR 505
Y V ++ E++PI+YTP VG ACQ+ +Y R GL+++ HD+ + D + E +V
Sbjct: 67 YDLVRHHLPELLPIIYTPVVGEACQRHSDLYLRSHGLYLSWHDRDDL-DAIFAAVEQEVD 125
Query: 506 AIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVGYEHP 667
IV++DGER+LGLGDLG GMGI +GKLALY+A GGI P + LP+ +DVG +P
Sbjct: 126 VIVISDGERVLGLGDLGIGGMGICIGKLALYSAAGGINPARTLPLCVDVGTNNP 179
>UniRef50_Q5K758 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 600
Score = 138 bits (335), Expect = 8e-32
Identities = 65/141 (46%), Positives = 90/141 (63%), Gaps = 3/141 (2%)
Frame = +2
Query: 242 KLSIDRYENPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYR 421
K + PL K+++L + + +LF+ + D + E+ PIVYTPTVG ACQK+ +Y
Sbjct: 95 KAHLQNLPTPLLKHVHLSKIRREDPNLFFSVMRDELTELAPIVYTPTVGEACQKYSQIYS 154
Query: 422 RPRGLFITIHDKGHVYDVLKNWPETDV---RAIVVTDGERILGLGDLGACGMGIPVGKLA 592
P GL++ I DK + ++L + V + +VVTDG RILGLGDLG GMGI VGKL
Sbjct: 155 GPEGLYLNIEDKDRIPEILHQYASKLVAPPQILVVTDGSRILGLGDLGIGGMGISVGKLN 214
Query: 593 LYTALGGIKPHQCLPITIDVG 655
LY A GG+ PH CLP+ +D+G
Sbjct: 215 LYVAGGGVNPHGCLPVVLDMG 235
>UniRef50_Q7K3R0 Cluster: Malic enzyme; n=2; Sophophora|Rep: Malic
enzyme - Drosophila melanogaster (Fruit fly)
Length = 633
Score = 136 bits (330), Expect = 3e-31
Identities = 71/186 (38%), Positives = 101/186 (54%)
Frame = +2
Query: 98 SGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLN 277
S + GL L NKG+AFT+ ER++L IHGLLP V+T +EQ E+C ++ + N +
Sbjct: 68 SKVDGLWMLNQSNYNKGLAFTLNERRVLSIHGLLPVAVRTIDEQAEICSNLLESFTNNVQ 127
Query: 278 KYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDK 457
+YIYL L RN LFY + N +P+ +++ +GL+I I D
Sbjct: 128 QYIYLTYLSRRNRRLFYYLLLSNPDRFVPMTDASGSIDLLMVHRMIHSMGQGLYICIKDL 187
Query: 458 GHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLP 637
GHV +L NWP VR ++V++G +L +GDLG M I L GGI P CL
Sbjct: 188 GHVSQILSNWPFRCVRCLLVSNGASVLSVGDLGVDEMPILFSNLHQNVVYGGIHPAYCLA 247
Query: 638 ITIDVG 655
+ +DVG
Sbjct: 248 VMLDVG 253
>UniRef50_P40375 Cluster: NAD-dependent malic enzyme; n=3;
Schizosaccharomyces pombe|Rep: NAD-dependent malic
enzyme - Schizosaccharomyces pombe (Fission yeast)
Length = 565
Score = 136 bits (328), Expect = 6e-31
Identities = 78/191 (40%), Positives = 112/191 (58%), Gaps = 7/191 (3%)
Frame = +2
Query: 104 LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRY----ENP 271
L G+ L P NK AFT EERQ I LPP V+T ++QV+ C D+Y + P
Sbjct: 13 LKGVTLLNSPRYNKDTAFTPEERQKFEISSRLPPIVETLQQQVDRC---YDQYKAIGDEP 69
Query: 272 LNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITI- 448
L K +YL L N+ LFY ++ ++ EM+PI+YTPT G A ++F +YR P G ++ I
Sbjct: 70 LQKNLYLSQLSVTNQTLFYALISQHLIEMIPIIYTPTEGDAIKQFSDIYRYPEGCYLDID 129
Query: 449 -HDKGHVYDVLKNWPETD-VRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKP 622
+D ++ L + ++D V I++TD E ILG+GD G G+ I V K L T G+ P
Sbjct: 130 HNDLSYIKQQLSEFGKSDSVEYIIITDSEGILGIGDQGVGGVLISVAKGHLMTLCAGLDP 189
Query: 623 HQCLPITIDVG 655
++ LPI +DVG
Sbjct: 190 NRFLPIVLDVG 200
>UniRef50_Q48796 Cluster: Malolactic enzyme; n=49; Bacteria|Rep:
Malolactic enzyme - Oenococcus oeni (Leuconostoc oenos)
Length = 541
Score = 135 bits (326), Expect = 1e-30
Identities = 70/180 (38%), Positives = 104/180 (57%), Gaps = 2/180 (1%)
Frame = +2
Query: 122 LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGL 301
L P +NKG AFT ER+ LG++GLLP +V+ +EQV+ + L K ++LM +
Sbjct: 8 LNDPFINKGTAFTEAEREELGLNGLLPAKVQALQEQVDQTYAQFQSKVSNLEKRLFLMEI 67
Query: 302 LDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRG-LFITIHDKGHVYDVL 478
+ N LFY+ + +V E MPIVY PT+ + + ++ P+G F+ I+ ++ L
Sbjct: 68 FNTNHVLFYKLFSQHVVEFMPIVYDPTIADTIENYSELFVEPQGAAFLDINHPENIQSTL 127
Query: 479 KNWPE-TDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVG 655
KN D++ +VV+D E ILG+GD G G+ I VGKL +YT GI P L + ID G
Sbjct: 128 KNAANGRDIKLLVVSDAEGILGIGDWGVQGVDIAVGKLMVYTVAAGIDPSTVLAVVIDAG 187
>UniRef50_P36013 Cluster: NAD-dependent malic enzyme, mitochondrial
precursor; n=15; Saccharomycetales|Rep: NAD-dependent
malic enzyme, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 669
Score = 133 bits (321), Expect = 4e-30
Identities = 71/185 (38%), Positives = 106/185 (57%), Gaps = 1/185 (0%)
Frame = +2
Query: 104 LSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKY 283
L L P NKG AFT EER+ + LLPP+V T +EQ+E + + PL K
Sbjct: 98 LESFQLLNSPLFNKGSAFTQEEREAFNLEALLPPQVNTLDEQLERSYKQLCYLKTPLAKN 157
Query: 284 IYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGH 463
++ L +N+ L++ + ++ E++PI+YTPT G A + +R+P G+F+ I +
Sbjct: 158 DFMTSLRVQNKVLYFALIRRHIKELVPIIYTPTEGDAIAAYSHRFRKPEGVFLDITEPDS 217
Query: 464 VYDVLKNW-PETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPI 640
+ L + + DV IVV+D E ILG+GD G G+ I + KLAL T GGI P + LP+
Sbjct: 218 IECRLATYGGDKDVDYIVVSDSEGILGIGDQGIGGVRIAISKLALMTLCGGIHPGRVLPV 277
Query: 641 TIDVG 655
+DVG
Sbjct: 278 CLDVG 282
>UniRef50_Q5KEY3 Cluster: Malic enzyme; n=1; Filobasidiella
neoformans|Rep: Malic enzyme - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 629
Score = 124 bits (299), Expect = 2e-27
Identities = 72/205 (35%), Positives = 111/205 (54%), Gaps = 16/205 (7%)
Frame = +2
Query: 98 SGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLN 277
+ L G L P LNKG FT EERQ+ G+ G LP V + E+Q + + + +
Sbjct: 48 TNLRGSALLNTPRLNKGAGFTREERQIFGLEGFLPYDVHSLEKQCLRAYNQLCKQPSVIL 107
Query: 278 KYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHD- 454
K+ +L L D+N+ LFYR + D + E++ ++YTP A + ++RRP G +I+ +
Sbjct: 108 KHAFLASLRDQNQVLFYRLMQDRLKELLGVLYTPGAAEAVAGYSSLFRRPVGCYISFPNQ 167
Query: 455 -------KGHVYDVLK--------NWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKL 589
+GH+ DV + N P+ + +VVTD E ILG+GD G G+ I K
Sbjct: 168 DGMRAQLEGHLTDVNRTADVAYDSNKPDDAIDLVVVTDAEAILGIGDQGVGGITISTSKA 227
Query: 590 ALYTALGGIKPHQCLPITIDVGYEH 664
ALYT GI P++ LP+ +D G ++
Sbjct: 228 ALYTLGAGINPNRILPVVLDCGTDN 252
>UniRef50_Q5KBK5 Cluster: Nad-dependent malic enzyme, putative; n=2;
Filobasidiella neoformans|Rep: Nad-dependent malic
enzyme, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 584
Score = 121 bits (292), Expect = 1e-26
Identities = 68/179 (37%), Positives = 98/179 (54%), Gaps = 1/179 (0%)
Frame = +2
Query: 122 LKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLNKYIYLMGL 301
L +P NKG AFT +ER + G LP V + E QV+ E + K +L +
Sbjct: 32 LNNPRFNKGSAFTHQERSEFALRGRLPYAVDSLEIQVKRAYEQYKSRETNILKNSFLQSM 91
Query: 302 LDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFIT-IHDKGHVYDVL 478
+N LFY + ++ EM PIVYTPT A + ++RR GL++T +K D L
Sbjct: 92 KAQNWTLFYALLQAHLVEMFPIVYTPTEADAIADYSHLFRRSEGLYLTPPGEKNMEEDFL 151
Query: 479 KNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVG 655
++ IVV+DGE ILG+GD G+ G+GI K +Y+ + G+ P +CL IT+DVG
Sbjct: 152 DACEGRELELIVVSDGEAILGIGDQGSGGIGISGAKAVIYSLIAGVDPAKCLAITLDVG 210
>UniRef50_Q2HCG7 Cluster: Malic enzyme; n=1; Chaetomium
globosum|Rep: Malic enzyme - Chaetomium globosum (Soil
fungus)
Length = 586
Score = 115 bits (277), Expect = 9e-25
Identities = 76/216 (35%), Positives = 109/216 (50%), Gaps = 20/216 (9%)
Frame = +2
Query: 77 SGDGQPTSGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSID 256
S G L G L H NKG AFT EER+ + GLLP ++T ++QV+
Sbjct: 22 STSGPLECALKGTVLLNHSYFNKGSAFTKEERRDFELSGLLPQSIQTLDQQVQRAYEQYS 81
Query: 257 RYENPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGL 436
+ L K +L + ++NE L+++ M +VYTPT G A + F ++RRP+G+
Sbjct: 82 ARPDDLAKNTFLTSMKEQNEVLYFK--------MFSVVYTPTEGDAIENFSRLFRRPQGV 133
Query: 437 FITIHDKGHVYDVLKNW-PETDVRAIVVT-------------------DGERILGLGDLG 556
F+ +HD V+ L W D+ IVVT DGE ILG+GD G
Sbjct: 134 FLNVHDCDRVHHDLSLWGMPDDIDYIVVTGATFHPRARSRLRYQLTKLDGEEILGIGDQG 193
Query: 557 ACGMGIPVGKLALYTALGGIKPHQCLPITIDVGYEH 664
G+ I V KLAL T GI P++ LP+ +D G ++
Sbjct: 194 CGGILISVAKLALMTLCAGIHPNRVLPVVLDCGTDN 229
>UniRef50_A3YYQ0 Cluster: Malate oxidoreductase; n=1; Synechococcus
sp. WH 5701|Rep: Malate oxidoreductase - Synechococcus
sp. WH 5701
Length = 517
Score = 115 bits (276), Expect = 1e-24
Identities = 61/150 (40%), Positives = 89/150 (59%), Gaps = 1/150 (0%)
Frame = +2
Query: 209 VKTQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVG 388
+++ E QVE + N L ++ + + L N LF+RF+AD++ +MPIVYTPTVG
Sbjct: 1 MESLETQVERHWQAFLSLRNDLERFRFAVALRQANLTLFHRFLADHIEAVMPIVYTPTVG 60
Query: 389 LACQKFGLVYRRPR-GLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACG 565
A Q+F L YR P G+F+ D + VL V I++TD + ILG+GD G G
Sbjct: 61 AAIQRFSLDYRTPSGGVFLAAPDLERIESVLSQAATGPVDLILITDSQGILGIGDQGIGG 120
Query: 566 MGIPVGKLALYTALGGIKPHQCLPITIDVG 655
+ I +GKLA+YT G+ P + LP+ +DVG
Sbjct: 121 IEICLGKLAVYTLCAGLDPARVLPLVLDVG 150
>UniRef50_A4RZU1 Cluster: Malic enzyme; n=2; Ostreococcus|Rep: Malic
enzyme - Ostreococcus lucimarinus CCE9901
Length = 539
Score = 95.1 bits (226), Expect = 1e-18
Identities = 62/160 (38%), Positives = 80/160 (50%), Gaps = 30/160 (18%)
Frame = +2
Query: 266 NPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFIT 445
+PL +Y+YL L + FYR + E+MP VYTPTVG AC+K+ + G++IT
Sbjct: 16 DPLERYVYLRELQRASAETFYRALVREPLELMPFVYTPTVGEACEKYHRLGIETNGVYIT 75
Query: 446 IHDKGHVYDVLK-NWPE---TDVRAIVVTDGE--------------------------RI 535
D G V L+ +W RA DGE RI
Sbjct: 76 ADDAGRVGAKLRGHWDRAAAARARAREGLDGEAAKRRGVDRRARADDGVAVAVVTDGERI 135
Query: 536 LGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVG 655
LGLGDLGA GMGI GK+ LYT G++P CLP+ +DVG
Sbjct: 136 LGLGDLGAGGMGISEGKILLYTVCAGVRPSACLPVCLDVG 175
>UniRef50_Q9S4T5 Cluster: NAD-malate oxidoreductase homolog; n=15;
Legionellales|Rep: NAD-malate oxidoreductase homolog -
Legionella pneumophila
Length = 117
Score = 89.8 bits (213), Expect = 5e-17
Identities = 45/99 (45%), Positives = 63/99 (63%)
Frame = +2
Query: 98 SGLSGLDHLKHPGLNKGMAFTIEERQLLGIHGLLPPRVKTQEEQVELCKLSIDRYENPLN 277
+ L G L P LNKG AFT EER+ G+ G LP RV+T +EQV+ L Y L
Sbjct: 19 TSLCGKPLLTTPQLNKGTAFTQEERKDFGLLGKLPHRVETLDEQVKRAYLQYSSYTTRLQ 78
Query: 278 KYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLA 394
++IYL L D+N+ +FY+ ++ ++ EM+PI+YTP VG A
Sbjct: 79 QHIYLNNLHDKNQIVFYKLLSRHLGEMLPIIYTPIVGAA 117
>UniRef50_A5C6I9 Cluster: Malic enzyme; n=1; Vitis vinifera|Rep:
Malic enzyme - Vitis vinifera (Grape)
Length = 498
Score = 76.6 bits (180), Expect = 5e-13
Identities = 36/72 (50%), Positives = 47/72 (65%)
Frame = +2
Query: 440 ITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIK 619
IT + H++ + + V IV+TDG RILGLGDLG G+GIP+GKL +Y A GI
Sbjct: 21 ITXNGIXHIWSDIGSXDLCQVDMIVITDGSRILGLGDLGVQGIGIPIGKLDMYVAAAGIN 80
Query: 620 PHQCLPITIDVG 655
P + LPI +DVG
Sbjct: 81 PQRILPIMLDVG 92
>UniRef50_Q8S484 Cluster: Putative NADP-dependent malic enzyme; n=1;
Zea mays|Rep: Putative NADP-dependent malic enzyme - Zea
mays (Maize)
Length = 309
Score = 60.9 bits (141), Expect = 3e-08
Identities = 36/82 (43%), Positives = 44/82 (53%)
Frame = +2
Query: 311 NEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWP 490
+E LFY+ + DNV E++P VYT T G V DVLKNWP
Sbjct: 225 DERLFYKLLIDNVVELLPFVYTTT-------------------------GKVLDVLKNWP 259
Query: 491 ETDVRAIVVTDGERILGLGDLG 556
+++ I VTD ERILGLGDLG
Sbjct: 260 HRNIQVIFVTDSERILGLGDLG 281
>UniRef50_UPI0000DB7FF6 Cluster: PREDICTED: hypothetical protein,
partial; n=1; Apis mellifera|Rep: PREDICTED:
hypothetical protein, partial - Apis mellifera
Length = 95
Score = 42.3 bits (95), Expect = 0.010
Identities = 19/37 (51%), Positives = 26/37 (70%)
Frame = +2
Query: 35 TYSEMERDRIGLWGSGDGQPTSGLSGLDHLKHPGLNK 145
T S ++RD++G G GD ++ L GLDHLK+P LNK
Sbjct: 59 TMSSVQRDQLGQRGHGDAMCSNLLRGLDHLKNPRLNK 95
>UniRef50_P54572 Cluster: Probable NAD-dependent malic enzyme 1;
n=4; Bacteria|Rep: Probable NAD-dependent malic enzyme 1
- Bacillus subtilis
Length = 439
Score = 41.9 bits (94), Expect = 0.013
Identities = 33/95 (34%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Frame = +2
Query: 368 VYTPTVGLACQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLG 547
VYTP V C+ L+ + P +K +Y + N +VTDG ILGLG
Sbjct: 111 VYTPGVADVCR---LIEKEP--------EKASIYTTISN------SVAIVTDGTAILGLG 153
Query: 548 DLGA-CGMGIPVGKLALYTALGGIKPHQCLPITID 649
++G+ GM + GK AL+ L GI +PI +D
Sbjct: 154 NIGSVAGMPVMEGKAALFDQLAGISG---IPILLD 185
>UniRef50_Q3W7J3 Cluster: Malate dehydrogenase; n=1; Frankia sp.
EAN1pec|Rep: Malate dehydrogenase - Frankia sp. EAN1pec
Length = 464
Score = 41.5 bits (93), Expect = 0.018
Identities = 22/48 (45%), Positives = 30/48 (62%), Gaps = 1/48 (2%)
Frame = +2
Query: 509 IVVTDGERILGLGDLG-ACGMGIPVGKLALYTALGGIKPHQCLPITID 649
IVVTDG +LGLGD+G A + + GK AL+ GG+ +PI +D
Sbjct: 142 IVVTDGTAVLGLGDIGPAAALPVMEGKAALFKHFGGV---DAVPICLD 186
>UniRef50_Q8U225 Cluster: Malate oxidoreductase; n=41; cellular
organisms|Rep: Malate oxidoreductase - Pyrococcus
furiosus
Length = 435
Score = 41.5 bits (93), Expect = 0.018
Identities = 24/47 (51%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Frame = +2
Query: 512 VVTDGERILGLGDLGA-CGMGIPVGKLALYTALGGIKPHQCLPITID 649
VVTDG ILGLG++G GM + GK L+ AL GI PI ID
Sbjct: 77 VVTDGSAILGLGNIGVLAGMPVMEGKCVLFKALAGI---DAFPILID 120
>UniRef50_Q5Y0M3 Cluster: Malate oxidoreductase; n=8; cellular
organisms|Rep: Malate oxidoreductase - uncultured
archaeon GZfos12E1
Length = 444
Score = 39.9 bits (89), Expect = 0.054
Identities = 20/47 (42%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Frame = +2
Query: 512 VVTDGERILGLGDLGA-CGMGIPVGKLALYTALGGIKPHQCLPITID 649
+VTDG R+LGLGD+GA + + GK L+ LGG+ P+ +D
Sbjct: 84 IVTDGTRVLGLGDVGAEAALPVMEGKAMLFKYLGGV---DAFPLCLD 127
>UniRef50_Q2KKD0 Cluster: Oxalacetate decarboxylase; n=11;
Lactobacillales|Rep: Oxalacetate decarboxylase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 390
Score = 39.1 bits (87), Expect = 0.095
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Frame = +2
Query: 467 YDVLKNWPETDVRAIVVTDGERILGLGDLGA-CGMGIPVGKLALYTALGGI 616
+++ + W + V+TDG +LGLG++G G+ I GK LY L G+
Sbjct: 49 HELAREWTISGKLIAVITDGSAVLGLGNMGTQAGLPIVEGKALLYKNLAGV 99
>UniRef50_A0DE35 Cluster: Malic enzyme; n=3; Paramecium
tetraurelia|Rep: Malic enzyme - Paramecium tetraurelia
Length = 687
Score = 39.1 bits (87), Expect = 0.095
Identities = 18/38 (47%), Positives = 27/38 (71%), Gaps = 1/38 (2%)
Frame = +2
Query: 506 AIVVTDGERILGLGDLG-ACGMGIPVGKLALYTALGGI 616
A ++T+G ILGLG++G + G+ + GK L+ ALGGI
Sbjct: 337 AAIITNGTAILGLGNIGPSAGLPVMEGKSVLFNALGGI 374
>UniRef50_Q9HKY7 Cluster: Malate oxidoreductase (Malic enzyme)
related protein; n=17; Archaea|Rep: Malate
oxidoreductase (Malic enzyme) related protein -
Thermoplasma acidophilum
Length = 467
Score = 36.7 bits (81), Expect = 0.51
Identities = 19/48 (39%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Frame = +2
Query: 512 VVTDGERILGLGDLG-ACGMGIPVGKLALYTALGGIKPHQCLPITIDV 652
++TDG R+LGLG++G M + GK ++ LGG+ +PI I V
Sbjct: 94 ILTDGTRVLGLGNIGPEAAMPVMEGKALIFNYLGGV---NAIPIPIRV 138
>UniRef50_UPI00006CF21C Cluster: Bowman-Birk serine protease
inhibitor family protein; n=1; Tetrahymena thermophila
SB210|Rep: Bowman-Birk serine protease inhibitor family
protein - Tetrahymena thermophila SB210
Length = 1467
Score = 36.3 bits (80), Expect = 0.67
Identities = 21/63 (33%), Positives = 29/63 (46%)
Frame = +2
Query: 476 LKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALYTALGGIKPHQCLPITIDVG 655
L NW IVV+ G + L LG G +P + + G+ PH L TIDV
Sbjct: 208 LVNWTCLQKNVIVVSGGIQNWALTSLGPLGQNVPASR-----TISGLTPHNQLIFTIDVF 262
Query: 656 YEH 664
Y++
Sbjct: 263 YQY 265
>UniRef50_Q2STW7 Cluster: Putative uncharacterized protein; n=1;
Burkholderia thailandensis E264|Rep: Putative
uncharacterized protein - Burkholderia thailandensis
(strain E264 / ATCC 700388 / DSM 13276 /CIP 106301)
Length = 647
Score = 34.3 bits (75), Expect = 2.7
Identities = 17/43 (39%), Positives = 22/43 (51%)
Frame = +2
Query: 470 DVLKNWPETDVRAIVVTDGERILGLGDLGACGMGIPVGKLALY 598
DVL+ +P T V DG + GLG+L CG P +L Y
Sbjct: 97 DVLRQFPHTYVERSPSGDGLHLFGLGELVECGKAGPGNRLECY 139
>UniRef50_Q116W6 Cluster: Putative uncharacterized protein; n=1;
Trichodesmium erythraeum IMS101|Rep: Putative
uncharacterized protein - Trichodesmium erythraeum
(strain IMS101)
Length = 1107
Score = 34.3 bits (75), Expect = 2.7
Identities = 27/88 (30%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Frame = +2
Query: 74 GSGDGQPTSGLSGLDHLKHPGL-NKGMAFTIEERQLLGIHGL-LPPRVKTQEEQVELCKL 247
GSG G +G + GL G++ E LLGI + LP ++K E + + +L
Sbjct: 609 GSGFGALGLKFTGCKIVDGFGLITLGISQNEFEINLLGIATMMLPTKLKDNYEPIAMAEL 668
Query: 248 SIDRYENPLNKYIYLMGLLDRNEHLFYR 331
+I NP+ I + G L N ++F R
Sbjct: 669 AIAGRFNPMEGVILIQGQLTENSYIFSR 696
>UniRef50_Q08PM3 Cluster: Hemin ABC transporter, periplasmic
hemin-binding protein; n=1; Stigmatella aurantiaca
DW4/3-1|Rep: Hemin ABC transporter, periplasmic
hemin-binding protein - Stigmatella aurantiaca DW4/3-1
Length = 332
Score = 34.3 bits (75), Expect = 2.7
Identities = 32/104 (30%), Positives = 44/104 (42%)
Frame = +2
Query: 215 TQEEQVELCKLSIDRYENPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLA 394
T EQ+ KL + EN + I GLL R E L F A+ + M T V
Sbjct: 143 TSAEQLRGAKLPVLILENSSKEGI--SGLLRRIEVLARVFNAEEAGQRMKQDITRQVAEL 200
Query: 395 CQKFGLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDG 526
+K L ++PR LF+ H G + K ET A++ G
Sbjct: 201 EKKIALAKKKPRVLFLYAHSPGEAFVYGK---ETGTHALIELAG 241
>UniRef50_A7PY09 Cluster: Chromosome chr15 scaffold_37, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr15 scaffold_37, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 651
Score = 34.3 bits (75), Expect = 2.7
Identities = 24/62 (38%), Positives = 32/62 (51%)
Frame = -3
Query: 562 ARAQIAQAQNTFSVGYNNGADVRLRPVLKNIVYMSLIVDRDEEAPWSAVHKPELLTGQAN 383
A+AQ A AQN+ +V N GA +L VLK S + R+EE +A + E A
Sbjct: 538 AQAQAALAQNSSTVSENQGA--KLVSVLKGQPQSSSTISREEELKRAATAEREKRAAAAE 595
Query: 382 RR 377
RR
Sbjct: 596 RR 597
>UniRef50_A1CKF3 Cluster: Stress response protein (Ish1), putative;
n=5; Pezizomycotina|Rep: Stress response protein (Ish1),
putative - Aspergillus clavatus
Length = 516
Score = 34.3 bits (75), Expect = 2.7
Identities = 24/64 (37%), Positives = 30/64 (46%), Gaps = 9/64 (14%)
Frame = -3
Query: 436 EAPW-SAVHKPELLTGQANRRSVHNWHHFSHVIRDETVEQML--------IAVQEPHKID 284
+A W S V KP GQA + HNWHH I D + L + V +P K D
Sbjct: 63 KANWDSKVQKP---LGQAAEHTTHNWHHAKEWIFDTWSDSQLKAFLDRHGVPVPQPRKRD 119
Query: 283 VLVK 272
VL+K
Sbjct: 120 VLLK 123
>UniRef50_UPI0000DA40E4 Cluster: PREDICTED: hypothetical protein;
n=2; Rattus norvegicus|Rep: PREDICTED: hypothetical
protein - Rattus norvegicus
Length = 193
Score = 33.9 bits (74), Expect = 3.6
Identities = 20/51 (39%), Positives = 23/51 (45%)
Frame = -2
Query: 581 PQGCPSRTRPNRPGPKYVLRRLQQWRGRPSPASS*EHRIHVPYRGS**RGP 429
P C R RP P R WRG P+P + + R P RGS RGP
Sbjct: 106 PTPCKRTPRRTRPAPCSARR----WRGHPAPRAQWQRREGRPRRGSQARGP 152
>UniRef50_Q4SHK3 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 5 SCAF14581, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 72
Score = 33.9 bits (74), Expect = 3.6
Identities = 19/50 (38%), Positives = 24/50 (48%)
Frame = -1
Query: 243 LHSSTCSSCVLTRGGNNPCMPKS*RSSMVKAMPLLRPGCLRWSRPERPLV 94
L S SS +RG P P SS ++ R G RWSRP RP++
Sbjct: 22 LKGSAASSAAASRGQKTPASPTVPGSSQLQT----RSGQARWSRPRRPML 67
>UniRef50_Q8R7R6 Cluster: Malic enzyme; n=10; cellular
organisms|Rep: Malic enzyme - Thermoanaerobacter
tengcongensis
Length = 394
Score = 33.9 bits (74), Expect = 3.6
Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 1/36 (2%)
Frame = +2
Query: 512 VVTDGERILGLGDLGA-CGMGIPVGKLALYTALGGI 616
VVTDG +LGLG++G + + GK L+ GGI
Sbjct: 66 VVTDGSAVLGLGNIGPYAALPVMEGKAVLFKEFGGI 101
>UniRef50_Q5SLE4 Cluster: CBS domain protein; n=7; Bacteria|Rep: CBS
domain protein - Thermus thermophilus (strain HB8 / ATCC
27634 / DSM 579)
Length = 143
Score = 33.9 bits (74), Expect = 3.6
Identities = 14/33 (42%), Positives = 22/33 (66%)
Frame = +2
Query: 446 IHDKGHVYDVLKNWPETDVRAIVVTDGERILGL 544
IH + V D L+ E D+ A++V +GER+LG+
Sbjct: 17 IHPEATVLDALRKLAEHDIGALLVMEGERLLGI 49
>UniRef50_Q4DMA9 Cluster: Mucin TcMUCII, putative; n=4; Trypanosoma
cruzi|Rep: Mucin TcMUCII, putative - Trypanosoma cruzi
Length = 290
Score = 33.9 bits (74), Expect = 3.6
Identities = 18/38 (47%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Frame = +2
Query: 2 EQSQATSGGKCTYSEM-ERDRIGLWGSGDGQPTSGLSG 112
E+SQ TS G T E+D GL SG G+ TSG +G
Sbjct: 112 EKSQGTSSGSATVQNRDEKDTPGLKNSGGGEQTSGRTG 149
>UniRef50_UPI0000F2DA74 Cluster: PREDICTED: hypothetical protein;
n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
protein - Monodelphis domestica
Length = 380
Score = 33.5 bits (73), Expect = 4.7
Identities = 20/51 (39%), Positives = 25/51 (49%)
Frame = -1
Query: 159 VKAMPLLRPGCLRWSRPERPLVGCPSPEPHNPIRSRSISLYVHFPPLVACD 7
VKA P PG SRPERP P+P +P+RS + PL+ D
Sbjct: 92 VKARPEACPGPAACSRPERP----PTPRSFHPLRSPRVRFSAPPAPLLTLD 138
>UniRef50_Q4RNM6 Cluster: Chromosome 21 SCAF15012, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 21 SCAF15012, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1187
Score = 33.5 bits (73), Expect = 4.7
Identities = 20/51 (39%), Positives = 26/51 (50%)
Frame = -1
Query: 261 YLSIESLHSSTCSSCVLTRGGNNPCMPKS*RSSMVKAMPLLRPGCLRWSRP 109
Y S+ES + T SC L G+ +P+S RSS L RP +WS P
Sbjct: 255 YNSLESSYQRTLQSC-LKSSGSVASLPQSDRSSSSSQESLNRPLTSKWSAP 304
>UniRef50_Q0STR8 Cluster: Malate oxidoreductase; n=2; Clostridium
perfringens|Rep: Malate oxidoreductase - Clostridium
perfringens (strain SM101 / Type A)
Length = 381
Score = 33.5 bits (73), Expect = 4.7
Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Frame = +2
Query: 461 HVYDVLKNWPETDVRAIVVTDGERILGLGDLGA-CGMGIPVGKLALYTALGGIKPHQCLP 637
H +LK V+TDG +LGLG++G G I K +Y L G+ +P
Sbjct: 48 HHPSMLKTLTSVGNSIAVITDGTAVLGLGNIGTLAGYPIVEAKALVYKDLAGV---NAIP 104
Query: 638 ITID 649
+ +D
Sbjct: 105 LCVD 108
>UniRef50_A4AEE1 Cluster: Dihydroorotase and related cyclic
amidohydrolase; n=1; marine actinobacterium
PHSC20C1|Rep: Dihydroorotase and related cyclic
amidohydrolase - marine actinobacterium PHSC20C1
Length = 470
Score = 33.5 bits (73), Expect = 4.7
Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Frame = +2
Query: 407 GLVYRRPRGLFITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGL--GDLGACGMGIPV 580
G Y P G IHD GH+ ++ +TD+R I+ + ++ G++ A G P
Sbjct: 153 GRDYPHPAGT--GIHDHGHLLQIMDQIAKTDIRFIIHPHDQGLMDYIEGEVLARGDNTPE 210
Query: 581 GKLALYTALGGI 616
G + Y A G+
Sbjct: 211 GYASAYAAREGV 222
>UniRef50_UPI0001560FE5 Cluster: PREDICTED: similar to KIAA2007
protein; n=2; Equus caballus|Rep: PREDICTED: similar to
KIAA2007 protein - Equus caballus
Length = 745
Score = 33.1 bits (72), Expect = 6.2
Identities = 19/49 (38%), Positives = 24/49 (48%)
Frame = -1
Query: 228 CSSCVLTRGGNNPCMPKS*RSSMVKAMPLLRPGCLRWSRPERPLVGCPS 82
C+S V + P+ RSS +PLLRP LR+S P P C S
Sbjct: 167 CASLVRASASPSRLFPRR-RSSSAVRVPLLRPLALRFSGPATPPCACES 214
>UniRef50_P16468 Cluster: NAD-dependent malic enzyme; n=32;
Bacteria|Rep: NAD-dependent malic enzyme - Bacillus
stearothermophilus (Geobacillus stearothermophilus)
Length = 478
Score = 33.1 bits (72), Expect = 6.2
Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Frame = +2
Query: 512 VVTDGERILGLGDLGA-CGMGIPVGKLALYTALGGIKPHQCLPITID 649
VV+DG +LGLGD+G M + GK L+ G+ PI +D
Sbjct: 144 VVSDGTAVLGLGDIGPYAAMPVMEGKAMLFKEFAGV---DAFPICLD 187
>UniRef50_Q1EI20 Cluster: Putative uncharacterized protein; n=2;
root|Rep: Putative uncharacterized protein - uncultured
organism
Length = 302
Score = 32.7 bits (71), Expect = 8.2
Identities = 10/20 (50%), Positives = 16/20 (80%)
Frame = +2
Query: 431 GLFITIHDKGHVYDVLKNWP 490
G+++TI + G + D+LKNWP
Sbjct: 210 GVYLTIREPGQITDILKNWP 229
>UniRef50_A0WC26 Cluster: Multi-sensor hybrid histidine kinase
precursor; n=2; Geobacter lovleyi SZ|Rep: Multi-sensor
hybrid histidine kinase precursor - Geobacter lovleyi SZ
Length = 1007
Score = 32.7 bits (71), Expect = 8.2
Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Frame = +2
Query: 386 GLACQKFGLVYRRPRGL-FITIHDKGHVYDVLKNWPETDVRAIVVTDG 526
G+ K +YR R FI HD+ H+++ +KN PE + IV DG
Sbjct: 198 GIFDSKGVFLYRTARANEFIGKHDQPHLFEQMKNGPEEGIIDIVSNDG 245
>UniRef50_Q8PTT0 Cluster: NAD-dependent malic enzyme; n=4; cellular
organisms|Rep: NAD-dependent malic enzyme -
Methanosarcina mazei (Methanosarcina frisia)
Length = 439
Score = 32.7 bits (71), Expect = 8.2
Identities = 34/120 (28%), Positives = 52/120 (43%), Gaps = 1/120 (0%)
Frame = +2
Query: 260 YENPLNKYIYLMGLLDRNEHLFYRFVADNVAEMMPIVYTPTVGLACQKFGLVYRRPRGLF 439
Y+ L + L G+L+ + R + D + + YTP V C+K R R
Sbjct: 44 YQESLAMHRRLGGVLEVASKVRLRTIHD-----LGVAYTPGVAEPCRKI----RENR--- 91
Query: 440 ITIHDKGHVYDVLKNWPETDVRAIVVTDGERILGLGDLGA-CGMGIPVGKLALYTALGGI 616
D ++Y + KN VVTDG +LGLG++G + I GK ++ GI
Sbjct: 92 ----DLAYLYTLKKN------TVAVVTDGSAVLGLGNIGPYAALPIMEGKAIIFKEFAGI 141
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 758,497,047
Number of Sequences: 1657284
Number of extensions: 17491382
Number of successful extensions: 54564
Number of sequences better than 10.0: 88
Number of HSP's better than 10.0 without gapping: 51655
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 54515
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 51239674196
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -