Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fprWP07_F_D11
(654 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 154 2e-37
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 154 2e-37
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 154 2e-37
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 154 2e-37
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 154 2e-37
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 154 2e-37
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 154 2e-37
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 132 8e-31
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 132 1e-30
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 132 1e-30
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 132 1e-30
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 122 1e-27
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 122 1e-27
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 114 2e-25
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 114 2e-25
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 114 2e-25
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 114 2e-25
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 114 2e-25
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 114 2e-25
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 114 2e-25
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 114 2e-25
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 114 2e-25
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 112 1e-24
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 112 1e-24
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 112 1e-24
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 112 1e-24
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 112 1e-24
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 112 1e-24
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 111 3e-24
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 111 3e-24
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 110 5e-24
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 110 5e-24
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 110 5e-24
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 110 5e-24
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 110 5e-24
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 110 5e-24
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 110 5e-24
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 109 8e-24
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 61 4e-09
BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein. 60 7e-09
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 50 5e-06
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 50 5e-06
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 50 5e-06
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 50 5e-06
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 50 5e-06
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 50 5e-06
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 50 5e-06
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 50 5e-06
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 50 5e-06
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 50 5e-06
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 50 5e-06
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 48 4e-05
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 40 0.010
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 40 0.010
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 40 0.010
AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving ... 40 0.010
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 40 0.010
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 40 0.010
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 40 0.010
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 40 0.010
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 40 0.010
AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving ... 40 0.010
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 40 0.010
AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving ... 40 0.010
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 40 0.010
AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinog... 39 0.018
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 37 0.055
AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving ... 37 0.072
AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving ... 34 0.51
AF141344-1|AAG49447.1| 119|Homo sapiens LYST-interacting protei... 32 1.6
BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain cont... 31 4.7
BC035605-1|AAH35605.1| 578|Homo sapiens schlafen family member ... 25 6.1
AK001122-1|BAA91512.1| 578|Homo sapiens protein ( Homo sapiens ... 25 6.1
BC133035-1|AAI33036.1| 129|Homo sapiens keratin associated prot... 30 6.3
BC130399-1|AAI30400.1| 129|Homo sapiens keratin associated prot... 30 6.3
AB126075-1|BAD20202.1| 129|Homo sapiens keratin associated prot... 30 6.3
AK096194-1|BAC04723.1| 138|Homo sapiens protein ( Homo sapiens ... 30 8.3
AB126079-1|BAD20206.1| 202|Homo sapiens keratin associated prot... 30 8.3
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 154 bits (374), Expect = 2e-37
Identities = 80/142 (56%), Positives = 93/142 (65%), Gaps = 11/142 (7%)
Frame = +2
Query: 257 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 403
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 404 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 583
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 584 YVANGTQFAIQYGSGSLSGFLS 649
YV NGT F I YGSGSLSG+LS
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLS 152
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 154 bits (374), Expect = 2e-37
Identities = 80/142 (56%), Positives = 93/142 (65%), Gaps = 11/142 (7%)
Frame = +2
Query: 257 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 403
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 404 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 583
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 584 YVANGTQFAIQYGSGSLSGFLS 649
YV NGT F I YGSGSLSG+LS
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLS 152
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 154 bits (374), Expect = 2e-37
Identities = 80/142 (56%), Positives = 93/142 (65%), Gaps = 11/142 (7%)
Frame = +2
Query: 257 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 403
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 404 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 583
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 584 YVANGTQFAIQYGSGSLSGFLS 649
YV NGT F I YGSGSLSG+LS
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLS 152
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 154 bits (374), Expect = 2e-37
Identities = 80/142 (56%), Positives = 93/142 (65%), Gaps = 11/142 (7%)
Frame = +2
Query: 257 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 403
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 404 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 583
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 584 YVANGTQFAIQYGSGSLSGFLS 649
YV NGT F I YGSGSLSG+LS
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLS 152
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 154 bits (374), Expect = 2e-37
Identities = 80/142 (56%), Positives = 93/142 (65%), Gaps = 11/142 (7%)
Frame = +2
Query: 257 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 403
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 404 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 583
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 584 YVANGTQFAIQYGSGSLSGFLS 649
YV NGT F I YGSGSLSG+LS
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLS 152
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 154 bits (374), Expect = 2e-37
Identities = 80/142 (56%), Positives = 93/142 (65%), Gaps = 11/142 (7%)
Frame = +2
Query: 257 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 403
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 404 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 583
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 584 YVANGTQFAIQYGSGSLSGFLS 649
YV NGT F I YGSGSLSG+LS
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLS 152
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 154 bits (374), Expect = 2e-37
Identities = 80/142 (56%), Positives = 93/142 (65%), Gaps = 11/142 (7%)
Frame = +2
Query: 257 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 403
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 404 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 583
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS T
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 584 YVANGTQFAIQYGSGSLSGFLS 649
YV NGT F I YGSGSLSG+LS
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLS 152
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 132 bits (320), Expect = 8e-31
Identities = 63/133 (47%), Positives = 87/133 (65%), Gaps = 5/133 (3%)
Frame = +2
Query: 266 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 430
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRTLNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 431 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 610
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 611 IQYGSGSLSGFLS 649
IQYG+G + G LS
Sbjct: 139 IQYGTGRVDGILS 151
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 132 bits (319), Expect = 1e-30
Identities = 63/133 (47%), Positives = 87/133 (65%), Gaps = 5/133 (3%)
Frame = +2
Query: 266 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 430
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 431 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 610
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 611 IQYGSGSLSGFLS 649
IQYG+G + G LS
Sbjct: 139 IQYGTGRVDGILS 151
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 132 bits (319), Expect = 1e-30
Identities = 63/133 (47%), Positives = 87/133 (65%), Gaps = 5/133 (3%)
Frame = +2
Query: 266 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 430
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 431 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 610
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 611 IQYGSGSLSGFLS 649
IQYG+G + G LS
Sbjct: 139 IQYGTGRVDGILS 151
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 132 bits (319), Expect = 1e-30
Identities = 63/133 (47%), Positives = 87/133 (65%), Gaps = 5/133 (3%)
Frame = +2
Query: 266 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 430
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 431 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFA 610
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S ++ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 611 IQYGSGSLSGFLS 649
IQYG+G + G LS
Sbjct: 139 IQYGTGRVDGILS 151
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 122 bits (293), Expect = 1e-27
Identities = 57/126 (45%), Positives = 82/126 (65%), Gaps = 5/126 (3%)
Frame = +2
Query: 287 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 451
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 22 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 81
Query: 452 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGS 631
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S ++ +GT+FAIQYG+G
Sbjct: 82 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGR 141
Query: 632 LSGFLS 649
+ G LS
Sbjct: 142 VDGILS 147
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 122 bits (293), Expect = 1e-27
Identities = 57/126 (45%), Positives = 82/126 (65%), Gaps = 5/126 (3%)
Frame = +2
Query: 287 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 451
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 26 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 85
Query: 452 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGS 631
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S ++ +GT+FAIQYG+G
Sbjct: 86 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGR 145
Query: 632 LSGFLS 649
+ G LS
Sbjct: 146 VDGILS 151
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 114 bits (275), Expect = 2e-25
Identities = 48/82 (58%), Positives = 62/82 (75%)
Frame = +2
Query: 404 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 583
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 584 YVANGTQFAIQYGSGSLSGFLS 649
Y NGT+ ++Y +G++SGFLS
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLS 159
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 114 bits (275), Expect = 2e-25
Identities = 48/82 (58%), Positives = 62/82 (75%)
Frame = +2
Query: 404 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 583
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 584 YVANGTQFAIQYGSGSLSGFLS 649
Y NGT+ ++Y +G++SGFLS
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLS 159
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 114 bits (275), Expect = 2e-25
Identities = 48/82 (58%), Positives = 62/82 (75%)
Frame = +2
Query: 404 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 583
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 584 YVANGTQFAIQYGSGSLSGFLS 649
Y NGT+ ++Y +G++SGFLS
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLS 159
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 114 bits (275), Expect = 2e-25
Identities = 48/82 (58%), Positives = 62/82 (75%)
Frame = +2
Query: 404 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 583
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 584 YVANGTQFAIQYGSGSLSGFLS 649
Y NGT+ ++Y +G++SGFLS
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLS 159
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 114 bits (275), Expect = 2e-25
Identities = 48/82 (58%), Positives = 62/82 (75%)
Frame = +2
Query: 404 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 583
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 584 YVANGTQFAIQYGSGSLSGFLS 649
Y NGT+ ++Y +G++SGFLS
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLS 159
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 114 bits (275), Expect = 2e-25
Identities = 48/82 (58%), Positives = 62/82 (75%)
Frame = +2
Query: 404 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 583
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 584 YVANGTQFAIQYGSGSLSGFLS 649
Y NGT+ ++Y +G++SGFLS
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLS 159
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 114 bits (275), Expect = 2e-25
Identities = 48/82 (58%), Positives = 62/82 (75%)
Frame = +2
Query: 404 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 583
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 584 YVANGTQFAIQYGSGSLSGFLS 649
Y NGT+ ++Y +G++SGFLS
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLS 159
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 114 bits (275), Expect = 2e-25
Identities = 48/82 (58%), Positives = 62/82 (75%)
Frame = +2
Query: 404 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 583
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 584 YVANGTQFAIQYGSGSLSGFLS 649
Y NGT+ ++Y +G++SGFLS
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLS 159
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 114 bits (275), Expect = 2e-25
Identities = 48/82 (58%), Positives = 62/82 (75%)
Frame = +2
Query: 404 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKT 583
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S +
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 584 YVANGTQFAIQYGSGSLSGFLS 649
Y NGT+ ++Y +G++SGFLS
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLS 159
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 112 bits (269), Expect = 1e-24
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 9/129 (6%)
Frame = +2
Query: 284 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 436
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 437 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 616
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 617 YGSGSLSGF 643
YGSGSL+GF
Sbjct: 134 YGSGSLTGF 142
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 112 bits (269), Expect = 1e-24
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 9/129 (6%)
Frame = +2
Query: 284 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 436
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 437 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 616
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 617 YGSGSLSGF 643
YGSGSL+GF
Sbjct: 134 YGSGSLTGF 142
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 112 bits (269), Expect = 1e-24
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 9/129 (6%)
Frame = +2
Query: 284 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 436
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 14 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 72
Query: 437 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 616
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 73 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 130
Query: 617 YGSGSLSGF 643
YGSGSL+GF
Sbjct: 131 YGSGSLTGF 139
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 112 bits (269), Expect = 1e-24
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 9/129 (6%)
Frame = +2
Query: 284 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 436
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 437 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 616
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 617 YGSGSLSGF 643
YGSGSL+GF
Sbjct: 134 YGSGSLTGF 142
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 112 bits (269), Expect = 1e-24
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 9/129 (6%)
Frame = +2
Query: 284 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 436
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 437 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 616
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 617 YGSGSLSGF 643
YGSGSL+GF
Sbjct: 134 YGSGSLTGF 142
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 112 bits (269), Expect = 1e-24
Identities = 62/129 (48%), Positives = 82/129 (63%), Gaps = 9/129 (6%)
Frame = +2
Query: 284 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 436
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 437 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQ 616
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S TY NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 617 YGSGSLSGF 643
YGSGSL+GF
Sbjct: 134 YGSGSLTGF 142
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 111 bits (266), Expect = 3e-24
Identities = 62/145 (42%), Positives = 83/145 (57%), Gaps = 12/145 (8%)
Frame = +2
Query: 248 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 397
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 398 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 571
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 572 KSKTYVANGTQFAIQYGSGSLSGFL 646
S TY + +I YG+GS++G L
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGIL 146
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 111 bits (266), Expect = 3e-24
Identities = 62/145 (42%), Positives = 83/145 (57%), Gaps = 12/145 (8%)
Frame = +2
Query: 248 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 397
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 398 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 571
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 572 KSKTYVANGTQFAIQYGSGSLSGFL 646
S TY + +I YG+GS++G L
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGIL 146
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 110 bits (264), Expect = 5e-24
Identities = 61/143 (42%), Positives = 85/143 (59%), Gaps = 10/143 (6%)
Frame = +2
Query: 248 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 397
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 398 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 577
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 578 KTYVANGTQFAIQYGSGSLSGFL 646
TY G F+IQYG+GSLSG +
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGII 148
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 110 bits (264), Expect = 5e-24
Identities = 61/143 (42%), Positives = 85/143 (59%), Gaps = 10/143 (6%)
Frame = +2
Query: 248 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 397
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 398 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 577
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 578 KTYVANGTQFAIQYGSGSLSGFL 646
TY G F+IQYG+GSLSG +
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGII 148
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 110 bits (264), Expect = 5e-24
Identities = 61/143 (42%), Positives = 85/143 (59%), Gaps = 10/143 (6%)
Frame = +2
Query: 248 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 397
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 398 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 577
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 578 KTYVANGTQFAIQYGSGSLSGFL 646
TY G F+IQYG+GSLSG +
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGII 148
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 110 bits (264), Expect = 5e-24
Identities = 61/143 (42%), Positives = 85/143 (59%), Gaps = 10/143 (6%)
Frame = +2
Query: 248 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 397
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 398 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 577
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 578 KTYVANGTQFAIQYGSGSLSGFL 646
TY G F+IQYG+GSLSG +
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGII 148
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 110 bits (264), Expect = 5e-24
Identities = 61/143 (42%), Positives = 85/143 (59%), Gaps = 10/143 (6%)
Frame = +2
Query: 248 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 397
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 398 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 577
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 578 KTYVANGTQFAIQYGSGSLSGFL 646
TY G F+IQYG+GSLSG +
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGII 148
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 110 bits (264), Expect = 5e-24
Identities = 61/143 (42%), Positives = 85/143 (59%), Gaps = 10/143 (6%)
Frame = +2
Query: 248 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 397
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 398 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 577
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 578 KTYVANGTQFAIQYGSGSLSGFL 646
TY G F+IQYG+GSLSG +
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGII 148
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 110 bits (264), Expect = 5e-24
Identities = 61/143 (42%), Positives = 85/143 (59%), Gaps = 10/143 (6%)
Frame = +2
Query: 248 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 397
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 398 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 577
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 578 KTYVANGTQFAIQYGSGSLSGFL 646
TY G F+IQYG+GSLSG +
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGII 148
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 109 bits (262), Expect = 8e-24
Identities = 61/145 (42%), Positives = 83/145 (57%), Gaps = 12/145 (8%)
Frame = +2
Query: 248 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 397
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSFRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLV 63
Query: 398 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 571
+PL NYLD +Y+G I IGTP Q F V+FDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVLFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 572 KSKTYVANGTQFAIQYGSGSLSGFL 646
S TY + +I YG+GS++G L
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGIL 146
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 60.9 bits (141), Expect = 4e-09
Identities = 24/52 (46%), Positives = 35/52 (67%)
Frame = +2
Query: 494 SNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFLS 649
SN+WVPS KC AC+ H +D+ S +Y NGT+ ++Y +G++SGFLS
Sbjct: 1 SNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLS 52
>BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein.
Length = 104
Score = 60.1 bits (139), Expect = 7e-09
Identities = 38/82 (46%), Positives = 49/82 (59%), Gaps = 9/82 (10%)
Frame = +2
Query: 284 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 436
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 437 VISIGTPPQSFKVVFDTGSSNL 502
ISIGTPPQ+F V+FDTGSS L
Sbjct: 76 EISIGTPPQNFLVLFDTGSSPL 97
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 50.4 bits (115), Expect = 5e-06
Identities = 26/73 (35%), Positives = 39/73 (53%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 608 AIQYGSGSLSGFL 646
++Y GS +GF+
Sbjct: 146 TVKYTQGSWTGFV 158
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 50.4 bits (115), Expect = 5e-06
Identities = 26/73 (35%), Positives = 39/73 (53%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 608 AIQYGSGSLSGFL 646
++Y GS +GF+
Sbjct: 146 TVKYTQGSWTGFV 158
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 50.4 bits (115), Expect = 5e-06
Identities = 26/73 (35%), Positives = 39/73 (53%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 13 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 66
Query: 608 AIQYGSGSLSGFL 646
++Y GS +GF+
Sbjct: 67 TVKYTQGSWTGFV 79
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 50.4 bits (115), Expect = 5e-06
Identities = 26/73 (35%), Positives = 39/73 (53%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 608 AIQYGSGSLSGFL 646
++Y GS +GF+
Sbjct: 146 TVKYTQGSWTGFV 158
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 50.4 bits (115), Expect = 5e-06
Identities = 26/73 (35%), Positives = 39/73 (53%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 608 AIQYGSGSLSGFL 646
++Y GS +GF+
Sbjct: 146 TVKYTQGSWTGFV 158
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 50.4 bits (115), Expect = 5e-06
Identities = 26/73 (35%), Positives = 39/73 (53%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 608 AIQYGSGSLSGFL 646
++Y GS +GF+
Sbjct: 146 TVKYTQGSWTGFV 158
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 50.4 bits (115), Expect = 5e-06
Identities = 26/73 (35%), Positives = 39/73 (53%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 608 AIQYGSGSLSGFL 646
++Y GS +GF+
Sbjct: 146 TVKYTQGSWTGFV 158
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 50.4 bits (115), Expect = 5e-06
Identities = 26/73 (35%), Positives = 39/73 (53%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 608 AIQYGSGSLSGFL 646
++Y GS +GF+
Sbjct: 146 TVKYTQGSWTGFV 158
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 50.4 bits (115), Expect = 5e-06
Identities = 26/73 (35%), Positives = 39/73 (53%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 608 AIQYGSGSLSGFL 646
++Y GS +GF+
Sbjct: 146 TVKYTQGSWTGFV 158
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 50.4 bits (115), Expect = 5e-06
Identities = 26/73 (35%), Positives = 39/73 (53%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 608 AIQYGSGSLSGFL 646
++Y GS +GF+
Sbjct: 146 TVKYTQGSWTGFV 158
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 50.4 bits (115), Expect = 5e-06
Identities = 26/73 (35%), Positives = 39/73 (53%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 608 AIQYGSGSLSGFL 646
++Y GS +GF+
Sbjct: 146 TVKYTQGSWTGFV 158
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 47.6 bits (108), Expect = 4e-05
Identities = 24/67 (35%), Positives = 36/67 (53%)
Frame = +2
Query: 446 IGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGS 625
IGTPPQ +++ DTGSSN V Y + +D+ +S TY + G ++Y
Sbjct: 3 IGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKYTQ 56
Query: 626 GSLSGFL 646
GS +GF+
Sbjct: 57 GSWTGFV 63
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 39.5 bits (88), Expect = 0.010
Identities = 24/75 (32%), Positives = 35/75 (46%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 608 AIQYGSGSLSGFLST 652
+ Y G G L T
Sbjct: 129 YVPYTQGKWEGELGT 143
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 39.5 bits (88), Expect = 0.010
Identities = 24/75 (32%), Positives = 35/75 (46%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 608 AIQYGSGSLSGFLST 652
+ Y G G L T
Sbjct: 129 YVPYTQGKWEGELGT 143
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 39.5 bits (88), Expect = 0.010
Identities = 24/75 (32%), Positives = 35/75 (46%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 608 AIQYGSGSLSGFLST 652
+ Y G G L T
Sbjct: 129 YVPYTQGKWEGELGT 143
>AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving
enzyme type B protein.
Length = 476
Score = 39.5 bits (88), Expect = 0.010
Identities = 24/75 (32%), Positives = 35/75 (46%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 608 AIQYGSGSLSGFLST 652
+ Y G G L T
Sbjct: 129 YVPYTQGKWEGELGT 143
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 39.5 bits (88), Expect = 0.010
Identities = 24/75 (32%), Positives = 35/75 (46%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 608 AIQYGSGSLSGFLST 652
+ Y G G L T
Sbjct: 129 YVPYTQGKWEGELGT 143
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 39.5 bits (88), Expect = 0.010
Identities = 24/75 (32%), Positives = 35/75 (46%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 608 AIQYGSGSLSGFLST 652
+ Y G G L T
Sbjct: 129 YVPYTQGKWEGELGT 143
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 39.5 bits (88), Expect = 0.010
Identities = 24/75 (32%), Positives = 35/75 (46%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 608 AIQYGSGSLSGFLST 652
+ Y G G L T
Sbjct: 129 YVPYTQGKWEGELGT 143
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 39.5 bits (88), Expect = 0.010
Identities = 24/75 (32%), Positives = 35/75 (46%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 62 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 115
Query: 608 AIQYGSGSLSGFLST 652
+ Y G G L T
Sbjct: 116 YVPYTQGKWEGELGT 130
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 39.5 bits (88), Expect = 0.010
Identities = 24/75 (32%), Positives = 35/75 (46%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 608 AIQYGSGSLSGFLST 652
+ Y G G L T
Sbjct: 129 YVPYTQGKWEGELGT 143
>AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving
enzyme I-432 protein.
Length = 432
Score = 39.5 bits (88), Expect = 0.010
Identities = 24/75 (32%), Positives = 35/75 (46%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 608 AIQYGSGSLSGFLST 652
+ Y G G L T
Sbjct: 129 YVPYTQGKWEGELGT 143
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 39.5 bits (88), Expect = 0.010
Identities = 24/75 (32%), Positives = 35/75 (46%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 608 AIQYGSGSLSGFLST 652
+ Y G G L T
Sbjct: 129 YVPYTQGKWEGELGT 143
>AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving
enzyme I-476 protein.
Length = 476
Score = 39.5 bits (88), Expect = 0.010
Identities = 24/75 (32%), Positives = 35/75 (46%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 608 AIQYGSGSLSGFLST 652
+ Y G G L T
Sbjct: 129 YVPYTQGKWEGELGT 143
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 39.5 bits (88), Expect = 0.010
Identities = 24/75 (32%), Positives = 35/75 (46%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 106 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 159
Query: 608 AIQYGSGSLSGFLST 652
+ Y G G L T
Sbjct: 160 YVPYTQGKWEGELGT 174
>AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 86
Score = 38.7 bits (86), Expect = 0.018
Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 9/70 (12%)
Frame = +2
Query: 275 SVMALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 427
+V+ RVPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 18 AVICKQRVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 76
Query: 428 YYGVISIGTP 457
Y+G ISIGTP
Sbjct: 77 YFGEISIGTP 86
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 37.1 bits (82), Expect = 0.055
Identities = 23/75 (30%), Positives = 34/75 (45%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQF 607
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLFSTYRDLRKGV 128
Query: 608 AIQYGSGSLSGFLST 652
+ Y G G L T
Sbjct: 129 YVPYTQGKWEGELGT 143
>AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving
enzyme isoform I-127 protein.
Length = 127
Score = 36.7 bits (81), Expect = 0.072
Identities = 19/53 (35%), Positives = 29/53 (54%)
Frame = +2
Query: 428 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTY 586
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S TY
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving
enzyme 2, EC 3.4.23. protein.
Length = 415
Score = 33.9 bits (74), Expect = 0.51
Identities = 18/59 (30%), Positives = 30/59 (50%)
Frame = +2
Query: 470 KVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSKTYVANGTQFAIQYGSGSLSGFL 646
+++ DTGSSN V Y + +D+ +S TY + G ++Y GS +GF+
Sbjct: 3 QILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFV 55
>AF141344-1|AAG49447.1| 119|Homo sapiens LYST-interacting protein
LIP8 protein.
Length = 119
Score = 32.3 bits (70), Expect = 1.6
Identities = 13/33 (39%), Positives = 16/33 (48%)
Frame = -2
Query: 650 WRGSRRGCRSRTVSRTGCHSRRTSWTCGCRTCC 552
W GS+R C + V + S SW CR CC
Sbjct: 8 WPGSKRECANCRVGTSSWRSSGWSWWKDCRPCC 40
>BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain
containing 11 protein.
Length = 514
Score = 30.7 bits (66), Expect = 4.7
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = -3
Query: 493 GSGVEYHLERLRRRADTDHSVVLSIK 416
G G E+HLER+RR ++++ SIK
Sbjct: 30 GQGAEHHLERIRRSHQKHNAILASIK 55
>BC035605-1|AAH35605.1| 578|Homo sapiens schlafen family member 12
protein.
Length = 578
Score = 25.4 bits (53), Expect(2) = 6.1
Identities = 12/51 (23%), Positives = 23/51 (45%)
Frame = -2
Query: 419 QDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSYDVMAPYIVPLRSWR 267
+DN M + + + ++ P +E SQ + + AP+ PL W+
Sbjct: 325 KDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINTSLPAPHSWPLLEWQ 375
Score = 23.4 bits (48), Expect(2) = 6.1
Identities = 8/27 (29%), Positives = 11/27 (40%)
Frame = -2
Query: 566 CRTCCAANKRCWCSGTFWKAPRGWRIR 486
C CA +C F K P W ++
Sbjct: 299 CGYVCALRVERFCCAVFAKEPDSWHVK 325
>AK001122-1|BAA91512.1| 578|Homo sapiens protein ( Homo sapiens
cDNA FLJ10260 fis, clone HEMBB1000973, moderately
similar to Mus musculus schlafen3 mRNA. ).
Length = 578
Score = 25.4 bits (53), Expect(2) = 6.1
Identities = 12/51 (23%), Positives = 23/51 (45%)
Frame = -2
Query: 419 QDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSYDVMAPYIVPLRSWR 267
+DN M + + + ++ P +E SQ + + AP+ PL W+
Sbjct: 325 KDNRVMQLTRKEWIQFMVEAEPKFSSSYEEVISQINASLPAPHSWPLLEWQ 375
Score = 23.4 bits (48), Expect(2) = 6.1
Identities = 8/27 (29%), Positives = 11/27 (40%)
Frame = -2
Query: 566 CRTCCAANKRCWCSGTFWKAPRGWRIR 486
C CA +C F K P W ++
Sbjct: 299 CGYVCALRVERFCCAVFAKEPDSWHVK 325
>BC133035-1|AAI33036.1| 129|Homo sapiens keratin associated protein
5-6 protein.
Length = 129
Score = 30.3 bits (65), Expect = 6.3
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = -2
Query: 644 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCS 525
GS+ GC S S+ GC S CGC C K C+CS
Sbjct: 65 GSKGGCGSCGGSKGGCGS------CGCSQCSCC-KPCYCS 97
>BC130399-1|AAI30400.1| 129|Homo sapiens keratin associated protein
5-6 protein.
Length = 129
Score = 30.3 bits (65), Expect = 6.3
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = -2
Query: 644 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCS 525
GS+ GC S S+ GC S CGC C K C+CS
Sbjct: 65 GSKGGCGSCGGSKGGCGS------CGCSQCSCC-KPCYCS 97
>AB126075-1|BAD20202.1| 129|Homo sapiens keratin associated protein
protein.
Length = 129
Score = 30.3 bits (65), Expect = 6.3
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = -2
Query: 644 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCS 525
GS+ GC S S+ GC S CGC C K C+CS
Sbjct: 65 GSKGGCGSCGGSKGGCGS------CGCSQCSCC-KPCYCS 97
>AK096194-1|BAC04723.1| 138|Homo sapiens protein ( Homo sapiens
cDNA FLJ38875 fis, clone MESAN2013936. ).
Length = 138
Score = 29.9 bits (64), Expect = 8.3
Identities = 14/45 (31%), Positives = 19/45 (42%)
Frame = -2
Query: 629 CRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCSGTFWKAPRGW 495
C S T C R + C +CC + + C CS T+W W
Sbjct: 75 CLSEEAGETAC--RASPGQCYVTSCCLS-RHCTCSLTWWDVLLNW 116
>AB126079-1|BAD20206.1| 202|Homo sapiens keratin associated protein
protein.
Length = 202
Score = 29.9 bits (64), Expect = 8.3
Identities = 18/66 (27%), Positives = 29/66 (43%)
Frame = -2
Query: 644 GSRRGCRSRTVSRTGCHSRRTSWTCGCRTCCAANKRCWCSGTFWKAPRGWRIRCRIPP*T 465
GS+ GC S S+ GC S S C+ CC ++ C + P + C +P
Sbjct: 119 GSKGGCGSCGGSKGGCGSCGCSQCNCCKPCCCSSGCGSCCQSSCCNPCCCQSSCCVPVCC 178
Query: 464 TAAACR 447
++ C+
Sbjct: 179 QSSCCK 184
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 94,102,616
Number of Sequences: 237096
Number of extensions: 2108727
Number of successful extensions: 4323
Number of sequences better than 10.0: 78
Number of HSP's better than 10.0 without gapping: 4074
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4284
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7310122300
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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