Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fprWP06_F_P15
(654 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 138 2e-32
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 138 2e-32
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 138 2e-32
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 137 3e-32
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 137 3e-32
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 137 3e-32
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 137 3e-32
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 137 3e-32
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 137 3e-32
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 137 3e-32
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 137 3e-32
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 137 3e-32
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 137 3e-32
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 137 3e-32
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 134 2e-31
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 134 2e-31
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 134 2e-31
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 134 2e-31
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 134 2e-31
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 134 2e-31
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 134 2e-31
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 134 2e-31
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 134 2e-31
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 134 2e-31
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 134 3e-31
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 134 3e-31
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 134 3e-31
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 134 3e-31
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 134 3e-31
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 134 3e-31
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 134 3e-31
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 134 3e-31
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 101 3e-31
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 101 3e-31
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 101 3e-31
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 101 5e-31
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 101 5e-31
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 132 8e-31
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 132 1e-30
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 131 2e-30
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 131 2e-30
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 131 2e-30
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 131 2e-30
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 131 2e-30
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 131 2e-30
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 131 2e-30
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 130 3e-30
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 130 3e-30
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 130 3e-30
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 130 3e-30
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 130 3e-30
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 130 3e-30
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 130 3e-30
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 130 3e-30
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 130 3e-30
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 130 3e-30
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 130 3e-30
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 130 3e-30
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 130 3e-30
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 128 1e-29
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 128 2e-29
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 128 2e-29
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 125 2e-28
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 122 1e-27
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 122 1e-27
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 122 1e-27
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 122 1e-27
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 122 1e-27
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 122 1e-27
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 122 1e-27
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 119 1e-26
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 119 1e-26
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 119 1e-26
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 119 1e-26
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 119 1e-26
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 116 7e-26
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 116 1e-25
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 109 1e-23
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 109 1e-23
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 109 1e-23
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 109 1e-23
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 101 2e-21
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 101 2e-21
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 100 4e-21
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 100 4e-21
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 97 6e-20
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 97 6e-20
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 97 6e-20
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 97 6e-20
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 97 6e-20
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 38 0.024
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 36 0.095
AL953897-5|CAI15880.1| 504|Homo sapiens chromosome 1 open readi... 33 1.2
AK125511-1|BAC86188.1| 559|Homo sapiens rome) (ELN). protein. 27 3.6
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 31 4.7
BC007559-1|AAH07559.1| 218|Homo sapiens eukaryotic translation ... 31 4.7
BC007335-1|AAH07335.2| 117|Homo sapiens EIF3S12 protein protein. 31 4.7
BC001031-1|AAH01031.1| 218|Homo sapiens eukaryotic translation ... 31 4.7
AY245432-1|AAP22070.1| 218|Homo sapiens eukaryotic translation ... 31 4.7
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein. 31 4.7
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 31 4.7
AF315506-1|AAK01365.1| 218|Homo sapiens ARG134 protein protein. 31 4.7
AF109355-1|AAQ13503.1| 218|Homo sapiens MSTP001 protein. 31 4.7
AB019392-1|BAA76626.1| 218|Homo sapiens M9 protein. 31 4.7
BC033329-1|AAH33329.1| 245|Homo sapiens KCTD2 protein protein. 30 8.3
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 138 bits (334), Expect = 2e-32
Identities = 77/192 (40%), Positives = 116/192 (60%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
I LNNG + P LG GTW ++T+A K+ AID+GYRHID AH+Y+ E E
Sbjct: 5 ILLNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENE 54
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP- 457
VG I +K+++ VVKRE++F+ +K+W +H++ V+ A + L L L+Y+DL L+HWP
Sbjct: 55 VGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPT 114
Query: 458 --------MSISQEG--VDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
+ + G V + + L+TW EE++ +GL ++IG+SNFN Q++ +L
Sbjct: 115 GFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKP 174
Query: 602 NCNVPPAVNQIE 637
PAVNQIE
Sbjct: 175 GLKYKPAVNQIE 186
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 138 bits (334), Expect = 2e-32
Identities = 76/190 (40%), Positives = 116/190 (61%), Gaps = 13/190 (6%)
Frame = +2
Query: 107 LNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 286
LNNG + P LG GTW ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 287 EVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPMS- 463
I +K+++ VVKRE++F+ +K+W +H++ V+ A + L L L+Y+DL L+HWP+
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIGF 116
Query: 464 --------ISQEG--VDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANC 607
+ + G V + + L+TW EE++ +GL ++IG+SNFN Q++ +L
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 608 NVPPAVNQIE 637
PAVNQIE
Sbjct: 177 KYKPAVNQIE 186
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 138 bits (334), Expect = 2e-32
Identities = 76/190 (40%), Positives = 116/190 (61%), Gaps = 13/190 (6%)
Frame = +2
Query: 107 LNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 286
LNNG + P LG GTW ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 287 EVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP--- 457
I +K+++ VVKRE++F+ +K+W +H++ V+ A + L L L+Y+DL L+HWP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 458 ------MSISQEG--VDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLLA--NC 607
+ + G V + + L+TW EE++ +GL ++IG+SNFN Q++ +L+
Sbjct: 117 RPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPGL 176
Query: 608 NVPPAVNQIE 637
PAVNQIE
Sbjct: 177 KYKPAVNQIE 186
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 137 bits (332), Expect = 3e-32
Identities = 76/190 (40%), Positives = 115/190 (60%), Gaps = 13/190 (6%)
Frame = +2
Query: 107 LNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 286
LNNG + P LG GTW ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 287 EVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP--- 457
I +K+++ VVKRE++F+ +K+W +H++ V+ A + L L L+Y+DL L+HWP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 458 ------MSISQEG--VDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANC 607
+ + G V + + L+TW EE++ +GL ++IG+SNFN Q++ +L
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 608 NVPPAVNQIE 637
PAVNQIE
Sbjct: 177 KYKPAVNQIE 186
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 137 bits (332), Expect = 3e-32
Identities = 76/190 (40%), Positives = 115/190 (60%), Gaps = 13/190 (6%)
Frame = +2
Query: 107 LNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 286
LNNG + P LG GTW ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 287 EVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP--- 457
I +K+++ VVKRE++F+ +K+W +H++ V+ A + L L L+Y+DL L+HWP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 458 ------MSISQEG--VDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANC 607
+ + G V + + L+TW EE++ +GL ++IG+SNFN Q++ +L
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 608 NVPPAVNQIE 637
PAVNQIE
Sbjct: 177 KYKPAVNQIE 186
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 137 bits (332), Expect = 3e-32
Identities = 76/190 (40%), Positives = 115/190 (60%), Gaps = 13/190 (6%)
Frame = +2
Query: 107 LNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 286
LNNG + P LG GTW ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 287 EVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP--- 457
I +K+++ VVKRE++F+ +K+W +H++ V+ A + L L L+Y+DL L+HWP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 458 ------MSISQEG--VDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANC 607
+ + G V + + L+TW EE++ +GL ++IG+SNFN Q++ +L
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 608 NVPPAVNQIE 637
PAVNQIE
Sbjct: 177 KYKPAVNQIE 186
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 137 bits (332), Expect = 3e-32
Identities = 76/190 (40%), Positives = 115/190 (60%), Gaps = 13/190 (6%)
Frame = +2
Query: 107 LNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 286
LNNG + P LG GTW ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 287 EVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP--- 457
I +K+++ VVKRE++F+ +K+W +H++ V+ A + L L L+Y+DL L+HWP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 458 ------MSISQEG--VDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANC 607
+ + G V + + L+TW EE++ +GL ++IG+SNFN Q++ +L
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 608 NVPPAVNQIE 637
PAVNQIE
Sbjct: 177 KYKPAVNQIE 186
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 137 bits (332), Expect = 3e-32
Identities = 76/190 (40%), Positives = 115/190 (60%), Gaps = 13/190 (6%)
Frame = +2
Query: 107 LNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 286
LNNG + P LG GTW ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 287 EVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP--- 457
I +K+++ VVKRE++F+ +K+W +H++ V+ A + L L L+Y+DL L+HWP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 458 ------MSISQEG--VDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANC 607
+ + G V + + L+TW EE++ +GL ++IG+SNFN Q++ +L
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 608 NVPPAVNQIE 637
PAVNQIE
Sbjct: 177 KYKPAVNQIE 186
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 137 bits (332), Expect = 3e-32
Identities = 76/190 (40%), Positives = 115/190 (60%), Gaps = 13/190 (6%)
Frame = +2
Query: 107 LNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 286
LNNG + P LG GTW ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 287 EVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP--- 457
I +K+++ VVKRE++F+ +K+W +H++ V+ A + L L L+Y+DL L+HWP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 458 ------MSISQEG--VDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANC 607
+ + G V + + L+TW EE++ +GL ++IG+SNFN Q++ +L
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 608 NVPPAVNQIE 637
PAVNQIE
Sbjct: 177 KYKPAVNQIE 186
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 137 bits (332), Expect = 3e-32
Identities = 76/190 (40%), Positives = 115/190 (60%), Gaps = 13/190 (6%)
Frame = +2
Query: 107 LNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 286
LNNG + P LG GTW ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 287 EVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP--- 457
I +K+++ VVKRE++F+ +K+W +H++ V+ A + L L L+Y+DL L+HWP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 458 ------MSISQEG--VDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANC 607
+ + G V + + L+TW EE++ +GL ++IG+SNFN Q++ +L
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 608 NVPPAVNQIE 637
PAVNQIE
Sbjct: 177 KYKPAVNQIE 186
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 137 bits (332), Expect = 3e-32
Identities = 76/190 (40%), Positives = 115/190 (60%), Gaps = 13/190 (6%)
Frame = +2
Query: 107 LNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 286
LNNG + P LG GTW ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 287 EVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP--- 457
I +K+++ VVKRE++F+ +K+W +H++ V+ A + L L L+Y+DL L+HWP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 458 ------MSISQEG--VDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANC 607
+ + G V + + L+TW EE++ +GL ++IG+SNFN Q++ +L
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 608 NVPPAVNQIE 637
PAVNQIE
Sbjct: 177 KYKPAVNQIE 186
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 137 bits (332), Expect = 3e-32
Identities = 76/190 (40%), Positives = 115/190 (60%), Gaps = 13/190 (6%)
Frame = +2
Query: 107 LNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 286
LNNG + P LG GTW ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 287 EVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP--- 457
I +K+++ VVKRE++F+ +K+W +H++ V+ A + L L L+Y+DL L+HWP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 458 ------MSISQEG--VDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANC 607
+ + G V + + L+TW EE++ +GL ++IG+SNFN Q++ +L
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 608 NVPPAVNQIE 637
PAVNQIE
Sbjct: 177 KYKPAVNQIE 186
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 137 bits (332), Expect = 3e-32
Identities = 76/190 (40%), Positives = 115/190 (60%), Gaps = 13/190 (6%)
Frame = +2
Query: 107 LNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 286
LNNG + P LG GTW ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 287 EVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP--- 457
I +K+++ VVKRE++F+ +K+W +H++ V+ A + L L L+Y+DL L+HWP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 458 ------MSISQEG--VDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANC 607
+ + G V + + L+TW EE++ +GL ++IG+SNFN Q++ +L
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 608 NVPPAVNQIE 637
PAVNQIE
Sbjct: 177 KYKPAVNQIE 186
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 137 bits (332), Expect = 3e-32
Identities = 76/190 (40%), Positives = 115/190 (60%), Gaps = 13/190 (6%)
Frame = +2
Query: 107 LNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 286
LNNG + P LG GTW ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 4 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 53
Query: 287 EVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP--- 457
I +K+++ VVKRE++F+ +K+W +H++ V+ A + L L L+Y+DL L+HWP
Sbjct: 54 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 113
Query: 458 ------MSISQEG--VDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANC 607
+ + G V + + L+TW EE++ +GL ++IG+SNFN Q++ +L
Sbjct: 114 KPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 173
Query: 608 NVPPAVNQIE 637
PAVNQIE
Sbjct: 174 KYKPAVNQIE 183
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 134 bits (325), Expect = 2e-31
Identities = 79/192 (41%), Positives = 111/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 134 bits (325), Expect = 2e-31
Identities = 79/192 (41%), Positives = 111/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 134 bits (325), Expect = 2e-31
Identities = 79/192 (41%), Positives = 111/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 134 bits (325), Expect = 2e-31
Identities = 79/192 (41%), Positives = 111/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 134 bits (325), Expect = 2e-31
Identities = 79/192 (41%), Positives = 111/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 134 bits (325), Expect = 2e-31
Identities = 79/192 (41%), Positives = 111/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 134 bits (325), Expect = 2e-31
Identities = 79/192 (41%), Positives = 111/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 134 bits (325), Expect = 2e-31
Identities = 79/192 (41%), Positives = 111/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 134 bits (325), Expect = 2e-31
Identities = 79/192 (41%), Positives = 111/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 134 bits (325), Expect = 2e-31
Identities = 79/192 (41%), Positives = 111/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 134 bits (324), Expect = 3e-31
Identities = 71/191 (37%), Positives = 113/191 (59%), Gaps = 12/191 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+ L+ G + P +G GTW ++ +++ A+ YA+ +GYRHID A +Y EPE
Sbjct: 6 VLLHTGQKMPLIGLGTWK----------SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPE 55
Query: 281 VGEVINKKIKDG-VVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP 457
+GE + + + G V RE++FVT+K+W+ H DVE A+R L L LEY+DL L+HWP
Sbjct: 56 IGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115
Query: 458 MSISQ------EGVD-----ENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLLAN 604
+ + + D ++ Y ETW+ E ++ KGL +++G+SNFN Q+ +L+
Sbjct: 116 YAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSV 175
Query: 605 CNVPPAVNQIE 637
+V PAV Q+E
Sbjct: 176 ASVRPAVLQVE 186
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 134 bits (324), Expect = 3e-31
Identities = 71/191 (37%), Positives = 113/191 (59%), Gaps = 12/191 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+ L+ G + P +G GTW ++ +++ A+ YA+ +GYRHID A +Y EPE
Sbjct: 6 VLLHTGQKMPLIGLGTWK----------SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPE 55
Query: 281 VGEVINKKIKDG-VVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP 457
+GE + + + G V RE++FVT+K+W+ H DVE A+R L L LEY+DL L+HWP
Sbjct: 56 IGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115
Query: 458 MSISQ------EGVD-----ENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLLAN 604
+ + + D ++ Y ETW+ E ++ KGL +++G+SNFN Q+ +L+
Sbjct: 116 YAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSV 175
Query: 605 CNVPPAVNQIE 637
+V PAV Q+E
Sbjct: 176 ASVRPAVLQVE 186
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 134 bits (324), Expect = 3e-31
Identities = 71/191 (37%), Positives = 113/191 (59%), Gaps = 12/191 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+ L+ G + P +G GTW ++ +++ A+ YA+ +GYRHID A +Y EPE
Sbjct: 6 VLLHTGQKMPLIGLGTWK----------SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPE 55
Query: 281 VGEVINKKIKDG-VVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP 457
+GE + + + G V RE++FVT+K+W+ H DVE A+R L L LEY+DL L+HWP
Sbjct: 56 IGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115
Query: 458 MSISQ------EGVD-----ENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLLAN 604
+ + + D ++ Y ETW+ E ++ KGL +++G+SNFN Q+ +L+
Sbjct: 116 YAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSV 175
Query: 605 CNVPPAVNQIE 637
+V PAV Q+E
Sbjct: 176 ASVRPAVLQVE 186
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 134 bits (324), Expect = 3e-31
Identities = 71/191 (37%), Positives = 113/191 (59%), Gaps = 12/191 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+ L+ G + P +G GTW ++ +++ A+ YA+ +GYRHID A +Y EPE
Sbjct: 6 VLLHTGQKMPLIGLGTWK----------SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPE 55
Query: 281 VGEVINKKIKDG-VVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP 457
+GE + + + G V RE++FVT+K+W+ H DVE A+R L L LEY+DL L+HWP
Sbjct: 56 IGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115
Query: 458 MSISQ------EGVD-----ENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLLAN 604
+ + + D ++ Y ETW+ E ++ KGL +++G+SNFN Q+ +L+
Sbjct: 116 YAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSV 175
Query: 605 CNVPPAVNQIE 637
+V PAV Q+E
Sbjct: 176 ASVRPAVLQVE 186
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 134 bits (324), Expect = 3e-31
Identities = 71/191 (37%), Positives = 113/191 (59%), Gaps = 12/191 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+ L+ G + P +G GTW ++ +++ A+ YA+ +GYRHID A +Y EPE
Sbjct: 6 VLLHTGQKMPLIGLGTWK----------SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPE 55
Query: 281 VGEVINKKIKDG-VVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP 457
+GE + + + G V RE++FVT+K+W+ H DVE A+R L L LEY+DL L+HWP
Sbjct: 56 IGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115
Query: 458 MSISQ------EGVD-----ENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLLAN 604
+ + + D ++ Y ETW+ E ++ KGL +++G+SNFN Q+ +L+
Sbjct: 116 YAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSV 175
Query: 605 CNVPPAVNQIE 637
+V PAV Q+E
Sbjct: 176 ASVRPAVLQVE 186
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 134 bits (324), Expect = 3e-31
Identities = 71/191 (37%), Positives = 113/191 (59%), Gaps = 12/191 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+ L+ G + P +G GTW ++ +++ A+ YA+ +GYRHID A +Y EPE
Sbjct: 6 VLLHTGQKMPLIGLGTWK----------SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPE 55
Query: 281 VGEVINKKIKDG-VVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP 457
+GE + + + G V RE++FVT+K+W+ H DVE A+R L L LEY+DL L+HWP
Sbjct: 56 IGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115
Query: 458 MSISQ------EGVD-----ENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLLAN 604
+ + + D ++ Y ETW+ E ++ KGL +++G+SNFN Q+ +L+
Sbjct: 116 YAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSV 175
Query: 605 CNVPPAVNQIE 637
+V PAV Q+E
Sbjct: 176 ASVRPAVLQVE 186
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 134 bits (324), Expect = 3e-31
Identities = 71/191 (37%), Positives = 113/191 (59%), Gaps = 12/191 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+ L+ G + P +G GTW ++ +++ A+ YA+ +GYRHID A +Y EPE
Sbjct: 6 VLLHTGQKMPLIGLGTWK----------SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPE 55
Query: 281 VGEVINKKIKDG-VVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP 457
+GE + + + G V RE++FVT+K+W+ H DVE A+R L L LEY+DL L+HWP
Sbjct: 56 IGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115
Query: 458 MSISQ------EGVD-----ENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLLAN 604
+ + + D ++ Y ETW+ E ++ KGL +++G+SNFN Q+ +L+
Sbjct: 116 YAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSV 175
Query: 605 CNVPPAVNQIE 637
+V PAV Q+E
Sbjct: 176 ASVRPAVLQVE 186
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 134 bits (324), Expect = 3e-31
Identities = 71/191 (37%), Positives = 113/191 (59%), Gaps = 12/191 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+ L+ G + P +G GTW ++ +++ A+ YA+ +GYRHID A +Y EPE
Sbjct: 6 VLLHTGQKMPLIGLGTWK----------SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPE 55
Query: 281 VGEVINKKIKDG-VVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP 457
+GE + + + G V RE++FVT+K+W+ H DVE A+R L L LEY+DL L+HWP
Sbjct: 56 IGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115
Query: 458 MSISQ------EGVD-----ENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLLAN 604
+ + + D ++ Y ETW+ E ++ KGL +++G+SNFN Q+ +L+
Sbjct: 116 YAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSV 175
Query: 605 CNVPPAVNQIE 637
+V PAV Q+E
Sbjct: 176 ASVRPAVLQVE 186
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 101 bits (242), Expect(2) = 3e-31
Identities = 46/88 (52%), Positives = 60/88 (68%)
Frame = +2
Query: 197 KLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDIFVTTKVWHHHHKQ 376
K+ +A+ AID GYRH D A+ Y E EVG I KIK+G V+RED+F+ TK+W HK+
Sbjct: 18 KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKK 77
Query: 377 ADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
+ VE A R L+ L L Y+DL L+HWPM
Sbjct: 78 SLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 54.0 bits (124), Expect(2) = 3e-31
Identities = 26/63 (41%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Frame = +2
Query: 455 PMSISQEGVDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANCNVPPAVN 628
P+ S + + D+L+TW E+++ GL ++IGVSNFN EQ++RLL P N
Sbjct: 134 PLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTN 193
Query: 629 QIE 637
QIE
Sbjct: 194 QIE 196
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 101 bits (242), Expect(2) = 3e-31
Identities = 46/88 (52%), Positives = 60/88 (68%)
Frame = +2
Query: 197 KLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDIFVTTKVWHHHHKQ 376
K+ +A+ AID GYRH D A+ Y E EVG I KIK+G V+RED+F+ TK+W HK+
Sbjct: 18 KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKK 77
Query: 377 ADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
+ VE A R L+ L L Y+DL L+HWPM
Sbjct: 78 SLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 54.0 bits (124), Expect(2) = 3e-31
Identities = 26/63 (41%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Frame = +2
Query: 455 PMSISQEGVDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANCNVPPAVN 628
P+ S + + D+L+TW E+++ GL ++IGVSNFN EQ++RLL P N
Sbjct: 134 PLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTN 193
Query: 629 QIE 637
QIE
Sbjct: 194 QIE 196
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 101 bits (242), Expect(2) = 3e-31
Identities = 46/88 (52%), Positives = 60/88 (68%)
Frame = +2
Query: 197 KLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDIFVTTKVWHHHHKQ 376
K+ +A+ AID GYRH D A+ Y E EVG I KIK+G V+RED+F+ TK+W HK+
Sbjct: 18 KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKK 77
Query: 377 ADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
+ VE A R L+ L L Y+DL L+HWPM
Sbjct: 78 SLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 54.0 bits (124), Expect(2) = 3e-31
Identities = 26/63 (41%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Frame = +2
Query: 455 PMSISQEGVDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANCNVPPAVN 628
P+ S + + D+L+TW E+++ GL ++IGVSNFN EQ++RLL P N
Sbjct: 134 PLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTN 193
Query: 629 QIE 637
QIE
Sbjct: 194 QIE 196
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 101 bits (242), Expect(2) = 5e-31
Identities = 46/88 (52%), Positives = 60/88 (68%)
Frame = +2
Query: 197 KLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDIFVTTKVWHHHHKQ 376
K+ +A+ AID GYRH D A+ Y E EVG I KIK+G V+RED+F+ TK+W HK+
Sbjct: 18 KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKK 77
Query: 377 ADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
+ VE A R L+ L L Y+DL L+HWPM
Sbjct: 78 SLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 53.2 bits (122), Expect(2) = 5e-31
Identities = 26/68 (38%), Positives = 39/68 (57%), Gaps = 2/68 (2%)
Frame = +2
Query: 455 PMSISQEGVDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANCNVPPAVN 628
P+ S + + D+L+TW E+++ GL ++IGVSNFN EQ++RLL P N
Sbjct: 134 PLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTN 193
Query: 629 QIEINLNL 652
QI I +
Sbjct: 194 QILIRFQI 201
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 101 bits (242), Expect(2) = 5e-31
Identities = 46/88 (52%), Positives = 60/88 (68%)
Frame = +2
Query: 197 KLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDIFVTTKVWHHHHKQ 376
K+ +A+ AID GYRH D A+ Y E EVG I KIK+G V+RED+F+ TK+W HK+
Sbjct: 18 KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKK 77
Query: 377 ADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
+ VE A R L+ L L Y+DL L+HWPM
Sbjct: 78 SLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 53.2 bits (122), Expect(2) = 5e-31
Identities = 26/68 (38%), Positives = 39/68 (57%), Gaps = 2/68 (2%)
Frame = +2
Query: 455 PMSISQEGVDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANCNVPPAVN 628
P+ S + + D+L+TW E+++ GL ++IGVSNFN EQ++RLL P N
Sbjct: 134 PLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTN 193
Query: 629 QIEINLNL 652
QI I +
Sbjct: 194 QILIRFQI 201
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 132 bits (320), Expect = 8e-31
Identities = 77/192 (40%), Positives = 107/192 (55%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG + KI DG VKREDIF T+K+W + H+ V A+ L++ L+YVDL L+H PM
Sbjct: 61 VGLAVRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPM 120
Query: 461 SISQ----EGVDEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 132 bits (318), Expect = 1e-30
Identities = 75/190 (39%), Positives = 114/190 (60%), Gaps = 13/190 (6%)
Frame = +2
Query: 107 LNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVG 286
LNNG + P LG GTW ++T+A K+ AID+GYRHID AH+Y+ E EVG
Sbjct: 7 LNNGAKMPILGLGTW----KSPPGQVTEAVKV------AIDVGYRHIDCAHVYQNENEVG 56
Query: 287 EVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP--- 457
I +K+++ VVKRE++F+ +K+W +H++ V+ A + L L L+Y+DL L+HWP
Sbjct: 57 VAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGF 116
Query: 458 ------MSISQEG--VDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANC 607
+ + G V + + L+T EE++ +GL ++IG+SNFN Q++ +L
Sbjct: 117 KPGKEFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGL 176
Query: 608 NVPPAVNQIE 637
PAVNQIE
Sbjct: 177 KYKPAVNQIE 186
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 131 bits (316), Expect = 2e-30
Identities = 77/192 (40%), Positives = 106/192 (55%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ AI+ G+RHID+AHLY E +
Sbjct: 10 VKLNDGHFMPVLGFGTYAPP------EVPRSKALE-VTKLAIEAGFRHIDSAHLYNNEEQ 62
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W H+ V A+ + L++ L+YVDL L+H PM
Sbjct: 63 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 122
Query: 461 SISQ----EGVDEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 123 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 182
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 183 GLKYKPVCNQVE 194
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 131 bits (316), Expect = 2e-30
Identities = 77/192 (40%), Positives = 106/192 (55%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPP------EVPRSKALE-VTKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W H+ V A+ + L++ L+YVDL L+H PM
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 461 SISQ----EGVDEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 131 bits (316), Expect = 2e-30
Identities = 77/192 (40%), Positives = 106/192 (55%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPP------EVPRSKALE-VTKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W H+ V A+ + L++ L+YVDL L+H PM
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 461 SISQ----EGVDEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 131 bits (316), Expect = 2e-30
Identities = 77/192 (40%), Positives = 106/192 (55%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPP------EVPRSKALE-VTKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W H+ V A+ + L++ L+YVDL L+H PM
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 461 SISQ----EGVDEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 131 bits (316), Expect = 2e-30
Identities = 77/192 (40%), Positives = 106/192 (55%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPP------EVPRSKALE-VTKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W H+ V A+ + L++ L+YVDL L+H PM
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 461 SISQ----EGVDEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 131 bits (316), Expect = 2e-30
Identities = 77/192 (40%), Positives = 106/192 (55%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPP------EVPRSKALE-VTKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W H+ V A+ + L++ L+YVDL L+H PM
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 461 SISQ----EGVDEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 131 bits (316), Expect = 2e-30
Identities = 77/192 (40%), Positives = 106/192 (55%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPP------EVPRSKALE-VTKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W H+ V A+ + L++ L+YVDL L+H PM
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 461 SISQ----EGVDEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 130 bits (315), Expect = 3e-30
Identities = 76/192 (39%), Positives = 110/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A+ AI+ G+ HID+AH+Y E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN ++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 130 bits (315), Expect = 3e-30
Identities = 76/192 (39%), Positives = 110/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A+ AI+ G+ HID+AH+Y E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN ++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYEPVCNQVE 192
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 130 bits (315), Expect = 3e-30
Identities = 76/192 (39%), Positives = 109/192 (56%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A+ AI+ GY HID+AH+Y E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGYHHIDSAHVYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+Y DL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN ++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYEPVCNQVE 192
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 130 bits (315), Expect = 3e-30
Identities = 76/192 (39%), Positives = 110/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A+ AI+ G+ HID+AH+Y E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN ++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 130 bits (315), Expect = 3e-30
Identities = 76/192 (39%), Positives = 110/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A+ AI+ G+ HID+AH+Y E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN ++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 130 bits (315), Expect = 3e-30
Identities = 76/192 (39%), Positives = 110/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A+ AI+ G+ HID+AH+Y E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN ++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 130 bits (315), Expect = 3e-30
Identities = 76/192 (39%), Positives = 110/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A+ AI+ G+ HID+AH+Y E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN ++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 130 bits (315), Expect = 3e-30
Identities = 76/192 (39%), Positives = 110/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A+ AI+ G+ HID+AH+Y E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN ++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 130 bits (315), Expect = 3e-30
Identities = 77/192 (40%), Positives = 107/192 (55%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ + AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPP------EVPRSKALEVS-KLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W H+ V A+ + L++ L+YVDL L+H PM
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 461 SISQ----EGVDEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 130 bits (315), Expect = 3e-30
Identities = 76/192 (39%), Positives = 110/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A+ AI+ G+ HID+AH+Y E +
Sbjct: 21 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQ 73
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 74 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 133
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN ++ +L
Sbjct: 134 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 193
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 194 GLKYKPVCNQVE 205
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 130 bits (315), Expect = 3e-30
Identities = 76/192 (39%), Positives = 110/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A+ AI+ G+ HID+AH+Y E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN ++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 130 bits (315), Expect = 3e-30
Identities = 76/192 (39%), Positives = 110/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A+ AI+ G+ HID+AH+Y E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN ++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 130 bits (315), Expect = 3e-30
Identities = 76/192 (39%), Positives = 110/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A+ AI+ G+ HID+AH+Y E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-AVKLAIEAGFHHIDSAHVYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ GL +SIGVSNFN ++ +L
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 128 bits (310), Expect = 1e-29
Identities = 76/192 (39%), Positives = 106/192 (55%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPP------EVPRSKALE-VTKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG V+REDIF T+K+W H+ V A+ + L++ L+YVDL L+H PM
Sbjct: 61 VGLAIRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 461 SISQ----EGVDEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 128 bits (309), Expect = 2e-29
Identities = 77/192 (40%), Positives = 109/192 (56%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ A AI+ G+RHID+AHLY E +
Sbjct: 5 VKLNDGHFMPVLGFGTYAPA------EVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQ 57
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + H+ A+ L+ L L+YVDL L+H+P+
Sbjct: 58 VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPV 117
Query: 461 SI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ +E + DEN +D TW E+ L +SIGVSNFN ++ +L
Sbjct: 118 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKP 177
Query: 602 NCNVPPAVNQIE 637
V P NQ+E
Sbjct: 178 GLQVKPVCNQVE 189
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 128 bits (308), Expect = 2e-29
Identities = 76/192 (39%), Positives = 105/192 (54%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+KLN+G P LG+GT+ E+ ++ L+ AI+ G+RHID+AHLY E +
Sbjct: 8 VKLNDGHFMPVLGFGTYAPP------EVPRSKALE-VTKLAIEAGFRHIDSAHLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG V REDIF T+K+W H+ V A+ + L++ L+YVDL L+H PM
Sbjct: 61 VGLAIRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120
Query: 461 SISQ----EGVDEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
S+ DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 125 bits (301), Expect = 2e-28
Identities = 72/175 (41%), Positives = 100/175 (57%), Gaps = 13/175 (7%)
Frame = +2
Query: 152 LGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKRE 331
LG E+ ++ L+ A AI+ G+RHID+AHLY E +VG I KI DG VKRE
Sbjct: 2 LGFGTYAPAEVPKSKALE-ATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKRE 60
Query: 332 DIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPMSI--SQEGV--DEN--- 490
DIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P+S+ +E + DEN
Sbjct: 61 DIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKDENGKI 120
Query: 491 ----IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANCNVPPAVNQIE 637
+D TW E+ GL +SIGVSNFN Q++ +L P NQ+E
Sbjct: 121 LFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 175
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 122 bits (294), Expect = 1e-27
Identities = 74/192 (38%), Positives = 106/192 (55%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
++LN+G P LG+GT+ E+ R ++ AI+ G+RHID+A+LY E +
Sbjct: 8 VELNDGHFMPVLGFGTYAPP------EVPRNRAVE-VTKLAIEAGFRHIDSAYLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + V+ A+ L++L L+YVDL L+H+PM
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
Query: 461 SISQEGV----DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
++ DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 122 bits (293), Expect = 1e-27
Identities = 74/192 (38%), Positives = 106/192 (55%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
++LN+G P LG+GT+ E+ R ++ AI+ G+RHID+A+LY E +
Sbjct: 8 VELNDGHFMPVLGFGTYAPP------EVPRNRAVE-VTKLAIEAGFRHIDSAYLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + V+ A+ L++L L+YVDL L+H+PM
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
Query: 461 SISQEGV----DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
++ DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 122 bits (293), Expect = 1e-27
Identities = 74/192 (38%), Positives = 106/192 (55%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
++LN+G P LG+GT+ E+ R ++ AI+ G+RHID+A+LY E +
Sbjct: 6 VELNDGHFMPVLGFGTYAPP------EVPRNRAVE-VTKLAIEAGFRHIDSAYLYNNEEQ 58
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + V+ A+ L++L L+YVDL L+H+PM
Sbjct: 59 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 118
Query: 461 SISQEGV----DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
++ DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 119 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 178
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 179 GLKYKPVCNQVE 190
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 122 bits (293), Expect = 1e-27
Identities = 74/192 (38%), Positives = 106/192 (55%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
++LN+G P LG+GT+ E+ R ++ AI+ G+RHID+A+LY E +
Sbjct: 8 VELNDGHFMPVLGFGTYAPP------EVPRNRAVE-VTKLAIEAGFRHIDSAYLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + V+ A+ L++L L+YVDL L+H+PM
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
Query: 461 SISQEGV----DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
++ DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 122 bits (293), Expect = 1e-27
Identities = 74/192 (38%), Positives = 106/192 (55%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
++LN+G P LG+GT+ E+ R ++ AI+ G+RHID+A+LY E +
Sbjct: 8 VELNDGHFMPVLGFGTYAPP------EVPRNRAVE-VTKLAIEAGFRHIDSAYLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + V+ A+ L++L L+YVDL L+H+PM
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
Query: 461 SISQEGV----DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
++ DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 122 bits (293), Expect = 1e-27
Identities = 74/192 (38%), Positives = 106/192 (55%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
++LN+G P LG+GT+ E+ R ++ AI+ G+RHID+A+LY E +
Sbjct: 8 VELNDGHFMPVLGFGTYAPP------EVPRNRAVE-VTKLAIEAGFRHIDSAYLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + V+ A+ L++L L+YVDL L+H+PM
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
Query: 461 SISQEGV----DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
++ DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 122 bits (293), Expect = 1e-27
Identities = 74/192 (38%), Positives = 106/192 (55%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
++LN+G P LG+GT+ E+ R ++ AI+ G+RHID+A+LY E +
Sbjct: 8 VELNDGHFMPVLGFGTYAPP------EVPRNRAVE-VTKLAIEAGFRHIDSAYLYNNEEQ 60
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VG I KI DG VKREDIF T+K+W + V+ A+ L++L L+YVDL L+H+PM
Sbjct: 61 VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120
Query: 461 SISQEGV----DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
++ DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 181 GLKYKPVCNQVE 192
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 119 bits (286), Expect = 1e-26
Identities = 64/192 (33%), Positives = 104/192 (54%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
++L+ + P +G GTW + K+++A+ AID GYRHID A++Y+ E E
Sbjct: 5 VELSTKAKMPIVGLGTWK----------SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHE 54
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VGE I +KI++ VKRED+F+ +K+W ++ V A L+ L L Y+D+ L+HWP
Sbjct: 55 VGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQ 114
Query: 461 SISQ-----------EGVDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
+ +L+ W EE++ +GL +++GVSNF+ Q+++LL
Sbjct: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 175 GLKYKPVTNQVE 186
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 119 bits (286), Expect = 1e-26
Identities = 64/192 (33%), Positives = 104/192 (54%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
++L+ + P +G GTW + K+++A+ AID GYRHID A++Y+ E E
Sbjct: 5 VELSTKAKMPIVGLGTWK----------SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHE 54
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VGE I +KI++ VKRED+F+ +K+W ++ V A L+ L L Y+D+ L+HWP
Sbjct: 55 VGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQ 114
Query: 461 SISQ-----------EGVDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
+ +L+ W EE++ +GL +++GVSNF+ Q+++LL
Sbjct: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 175 GLKYKPVTNQVE 186
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 119 bits (286), Expect = 1e-26
Identities = 64/192 (33%), Positives = 104/192 (54%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
++L+ + P +G GTW + K+++A+ AID GYRHID A++Y+ E E
Sbjct: 5 VELSTKAKMPIVGLGTWK----------SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHE 54
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VGE I +KI++ VKRED+F+ +K+W ++ V A L+ L L Y+D+ L+HWP
Sbjct: 55 VGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQ 114
Query: 461 SISQ-----------EGVDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
+ +L+ W EE++ +GL +++GVSNF+ Q+++LL
Sbjct: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 175 GLKYKPVTNQVE 186
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 119 bits (286), Expect = 1e-26
Identities = 64/192 (33%), Positives = 104/192 (54%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
++L+ + P +G GTW + K+++A+ AID GYRHID A++Y+ E E
Sbjct: 5 VELSTKAKMPIVGLGTWK----------SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHE 54
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VGE I +KI++ VKRED+F+ +K+W ++ V A L+ L L Y+D+ L+HWP
Sbjct: 55 VGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQ 114
Query: 461 SISQ-----------EGVDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
+ +L+ W EE++ +GL +++GVSNF+ Q+++LL
Sbjct: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 175 GLKYKPVTNQVE 186
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 119 bits (286), Expect = 1e-26
Identities = 64/192 (33%), Positives = 104/192 (54%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
++L+ + P +G GTW + K+++A+ AID GYRHID A++Y+ E E
Sbjct: 5 VELSTKAKMPIVGLGTWK----------SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHE 54
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VGE I +KI++ VKRED+F+ +K+W ++ V A L+ L L Y+D+ L+HWP
Sbjct: 55 VGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQ 114
Query: 461 SISQ-----------EGVDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
+ +L+ W EE++ +GL +++GVSNF+ Q+++LL
Sbjct: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 175 GLKYKPVTNQVE 186
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 116 bits (279), Expect = 7e-26
Identities = 63/192 (32%), Positives = 103/192 (53%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
++L+ + P +G GTW + K+++A+ AID GYRHID A++Y+ E E
Sbjct: 5 VELSTKAKMPIVGLGTWK----------SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHE 54
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VGE I +KI++ VKRED+F+ +K+W ++ V A L+ L Y+D+ L+HWP
Sbjct: 55 VGEAIQEKIQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQ 114
Query: 461 SISQ-----------EGVDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--A 601
+ +L+ W EE++ +GL +++GVSNF+ Q+++LL
Sbjct: 115 GFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKP 174
Query: 602 NCNVPPAVNQIE 637
P NQ+E
Sbjct: 175 GLKYKPVTNQVE 186
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 116 bits (278), Expect = 1e-25
Identities = 71/183 (38%), Positives = 100/183 (54%), Gaps = 13/183 (7%)
Frame = +2
Query: 128 PALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKI 307
P LG+GT+ E+ R ++ AI+ G+RHID+A+LY E +VG I KI
Sbjct: 2 PVLGFGTYAPP------EVPRNRAVE-VTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKI 54
Query: 308 KDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPMSISQEGV-- 481
DG VKREDIF T+K+W + V+ A+ L++L L+YVDL L+H+PM++
Sbjct: 55 ADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPL 114
Query: 482 --DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL--ANCNVPPAVN 628
DEN +D TW E+ GL +SIGVSNFN Q++ +L P N
Sbjct: 115 PKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCN 174
Query: 629 QIE 637
Q+E
Sbjct: 175 QVE 177
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 109 bits (261), Expect = 1e-23
Identities = 71/192 (36%), Positives = 99/192 (51%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
I L++G P +G GT+ E + T ++ AID GYRHID A++Y+ E E
Sbjct: 10 IPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VGE I +KI +G V+REDIF K+W +H V + LR L L+YVDL ++ PM
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 461 SISQEGV----DENIDYL-------ETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLLANC 607
+ DEN +L TW E GL +S+GVSNFN Q++ +L
Sbjct: 124 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 183
Query: 608 NV--PPAVNQIE 637
+ P NQ+E
Sbjct: 184 GLKHKPVSNQVE 195
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 109 bits (261), Expect = 1e-23
Identities = 71/192 (36%), Positives = 99/192 (51%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
I L++G P +G GT+ E + T ++ AID GYRHID A++Y+ E E
Sbjct: 10 IPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VGE I +KI +G V+REDIF K+W +H V + LR L L+YVDL ++ PM
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 461 SISQEGV----DENIDYL-------ETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLLANC 607
+ DEN +L TW E GL +S+GVSNFN Q++ +L
Sbjct: 124 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 183
Query: 608 NV--PPAVNQIE 637
+ P NQ+E
Sbjct: 184 GLKHKPVSNQVE 195
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 109 bits (261), Expect = 1e-23
Identities = 71/192 (36%), Positives = 99/192 (51%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
I L++G P +G GT+ E + T ++ AID GYRHID A++Y+ E E
Sbjct: 10 IPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VGE I +KI +G V+REDIF K+W +H V + LR L L+YVDL ++ PM
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 461 SISQEGV----DENIDYL-------ETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLLANC 607
+ DEN +L TW E GL +S+GVSNFN Q++ +L
Sbjct: 124 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 183
Query: 608 NV--PPAVNQIE 637
+ P NQ+E
Sbjct: 184 GLKHKPVSNQVE 195
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 109 bits (261), Expect = 1e-23
Identities = 71/192 (36%), Positives = 99/192 (51%), Gaps = 13/192 (6%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
I L++G P +G GT+ E + T ++ AID GYRHID A++Y+ E E
Sbjct: 10 IPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 281 VGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
VGE I +KI +G V+REDIF K+W +H V + LR L L+YVDL ++ PM
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 461 SISQEGV----DENIDYL-------ETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLLANC 607
+ DEN +L TW E GL +S+GVSNFN Q++ +L
Sbjct: 124 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 183
Query: 608 NV--PPAVNQIE 637
+ P NQ+E
Sbjct: 184 GLKHKPVSNQVE 195
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 101 bits (242), Expect = 2e-21
Identities = 49/125 (39%), Positives = 76/125 (60%), Gaps = 1/125 (0%)
Frame = +2
Query: 101 IKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEPE 280
+ L+ G + P +G GTW ++ +++ A+ YA+ +GYRHID A +Y EPE
Sbjct: 6 VLLHTGQKMPLIGLGTWK----------SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPE 55
Query: 281 VGEVINKKIKDG-VVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP 457
+GE + + + G V RE++FVT+K+W+ H DVE A+R L L LEY+DL L+HWP
Sbjct: 56 IGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWP 115
Query: 458 MSISQ 472
+ +
Sbjct: 116 YAFER 120
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 101 bits (242), Expect = 2e-21
Identities = 46/88 (52%), Positives = 60/88 (68%)
Frame = +2
Query: 197 KLQDALSYAIDIGYRHIDTAHLYRVEPEVGEVINKKIKDGVVKREDIFVTTKVWHHHHKQ 376
K+ +A+ AID GYRH D A+ Y E EVG I KIK+G V+RED+F+ TK+W HK+
Sbjct: 18 KVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKK 77
Query: 377 ADVEVAVRDCLRRLNLEYVDLVLVHWPM 460
+ VE A R L+ L L Y+DL L+HWPM
Sbjct: 78 SLVETACRKSLKALKLNYLDLYLIHWPM 105
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 100 bits (240), Expect = 4e-21
Identities = 51/127 (40%), Positives = 78/127 (61%)
Frame = +2
Query: 98 TIKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEP 277
+++LN+G P LG+GT+ + T + +A AID+G+RHID+A+LY+ E
Sbjct: 10 SVRLNDGPFMPVLGFGTYAP-------DHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEE 62
Query: 278 EVGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP 457
EVG+ I +KI DG VKRE+IF T K+W + V A+ L++L +YVDL ++H P
Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
Query: 458 MSISQEG 478
++ Q G
Sbjct: 123 FAMKQPG 129
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 100 bits (240), Expect = 4e-21
Identities = 51/127 (40%), Positives = 78/127 (61%)
Frame = +2
Query: 98 TIKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEP 277
+++LN+G P LG+GT+ + T + +A AID+G+RHID+A+LY+ E
Sbjct: 10 SVRLNDGPFMPVLGFGTYAP-------DHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEE 62
Query: 278 EVGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP 457
EVG+ I +KI DG VKRE+IF T K+W + V A+ L++L +YVDL ++H P
Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
Query: 458 MSISQEG 478
++ Q G
Sbjct: 123 FAMKQPG 129
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 96.7 bits (230), Expect = 6e-20
Identities = 49/123 (39%), Positives = 76/123 (61%)
Frame = +2
Query: 98 TIKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEP 277
+++LN+G P LG+GT+ + T + +A AID+G+RHID+A+LY+ E
Sbjct: 10 SVRLNDGPFMPVLGFGTYAP-------DHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEE 62
Query: 278 EVGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP 457
EVG+ I +KI DG VKRE+IF T K+W + V A+ L++L +YVDL ++H P
Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
Query: 458 MSI 466
++
Sbjct: 123 FAM 125
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 96.7 bits (230), Expect = 6e-20
Identities = 49/123 (39%), Positives = 76/123 (61%)
Frame = +2
Query: 98 TIKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEP 277
+++LN+G P LG+GT+ + T + +A AID+G+RHID+A+LY+ E
Sbjct: 10 SVRLNDGPFMPVLGFGTYAP-------DHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEE 62
Query: 278 EVGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP 457
EVG+ I +KI DG VKRE+IF T K+W + V A+ L++L +YVDL ++H P
Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
Query: 458 MSI 466
++
Sbjct: 123 FAM 125
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 96.7 bits (230), Expect = 6e-20
Identities = 56/133 (42%), Positives = 76/133 (57%), Gaps = 13/133 (9%)
Frame = +2
Query: 278 EVGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP 457
EVG I KI DG VKREDIF T+K+W + H+ V A+ L+ L L+YVDL L+H+P
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Query: 458 MSI--SQEGV--DEN-------IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL-- 598
+S+ +E + DEN +D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 86 VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 145
Query: 599 ANCNVPPAVNQIE 637
P NQ+E
Sbjct: 146 PGLKYKPVCNQVE 158
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 96.7 bits (230), Expect = 6e-20
Identities = 49/123 (39%), Positives = 76/123 (61%)
Frame = +2
Query: 98 TIKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEP 277
+++LN+G P LG+GT+ + T + +A AID+G+RHID+A+LY+ E
Sbjct: 10 SVRLNDGPFMPVLGFGTYAP-------DHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEE 62
Query: 278 EVGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP 457
EVG+ I +KI DG VKRE+IF T K+W + V A+ L++L +YVDL ++H P
Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
Query: 458 MSI 466
++
Sbjct: 123 FAM 125
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 96.7 bits (230), Expect = 6e-20
Identities = 49/123 (39%), Positives = 75/123 (60%)
Frame = +2
Query: 98 TIKLNNGIEFPALGYGTWLGLNDKMEFEITDARKLQDALSYAIDIGYRHIDTAHLYRVEP 277
++KLN+G P LG+GT + M +++A+ AID+GYRHID+A+ + E
Sbjct: 8 SVKLNDGKFMPILGFGTSVARKVAMS-------NVEEAVQVAIDVGYRHIDSAYTHLNEE 60
Query: 278 EVGEVINKKIKDGVVKREDIFVTTKVWHHHHKQADVEVAVRDCLRRLNLEYVDLVLVHWP 457
+G+ I KKI +G VKR+DIF TTKVW + V+ + L++L L Y+DL L H+P
Sbjct: 61 GIGQAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFP 120
Query: 458 MSI 466
+ +
Sbjct: 121 VPL 123
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 38.3 bits (85), Expect = 0.024
Identities = 16/36 (44%), Positives = 22/36 (61%)
Frame = +2
Query: 491 IDYLETWRGFEEVLKKGLTRSIGVSNFNIEQMKRLL 598
+D TW E+ GL +SIGVSNFN Q++ +L
Sbjct: 19 VDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 54
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 36.3 bits (80), Expect = 0.095
Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Frame = +2
Query: 506 TWRGFEEVLKKGLTRSIGVSNFNIEQMKRLLANCNV--PPAVNQIE 637
TW E GL +S+GVSNFN Q++ +L + P NQ+E
Sbjct: 28 TWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVE 73
>AL953897-5|CAI15880.1| 504|Homo sapiens chromosome 1 open reading
frame 167 protein.
Length = 504
Score = 32.7 bits (71), Expect = 1.2
Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 6/65 (9%)
Frame = +1
Query: 394 GARLPQETESGVRGLGIGALANVDLARRGRRKYRLPGDV------ERV*GGPQEGTDQVH 555
G P + +GL +G VD A+R R ++ PG + +R+ P++ TD H
Sbjct: 208 GPGSPPSRRAQGKGLSLGRSTVVDPAQRSRLEHTSPGSLREEEIAQRLLSHPRQRTDSRH 267
Query: 556 RRVQL 570
RVQ+
Sbjct: 268 ERVQI 272
>AK125511-1|BAC86188.1| 559|Homo sapiens rome) (ELN). protein.
Length = 559
Score = 26.6 bits (56), Expect(2) = 3.6
Identities = 6/9 (66%), Positives = 7/9 (77%)
Frame = +3
Query: 423 WSTWTWYWC 449
W +WTW WC
Sbjct: 542 WCSWTWSWC 550
Score = 25.8 bits (54), Expect(2) = 6.1
Identities = 6/9 (66%), Positives = 6/9 (66%)
Frame = +3
Query: 423 WSTWTWYWC 449
W WTW WC
Sbjct: 524 WHPWTWSWC 532
Score = 23.0 bits (47), Expect(2) = 6.1
Identities = 5/8 (62%), Positives = 7/8 (87%)
Frame = +3
Query: 429 TWTWYWCT 452
TW+W WC+
Sbjct: 537 TWSWCWCS 544
Score = 23.0 bits (47), Expect(2) = 3.6
Identities = 5/8 (62%), Positives = 7/8 (87%)
Frame = +3
Query: 429 TWTWYWCT 452
TW+W WC+
Sbjct: 546 TWSWCWCS 553
>X90568-1|CAA62188.1|26926|Homo sapiens titin protein.
Length = 26926
Score = 30.7 bits (66), Expect = 4.7
Identities = 14/29 (48%), Positives = 19/29 (65%), Gaps = 1/29 (3%)
Frame = -3
Query: 580 FDVEVGHADGPGQ-SLLEDLLKPSPRLQV 497
FD E+ AD PGQ L +LL+PSP ++
Sbjct: 4919 FDAEISEADIPGQWKLKGELLRPSPTCEI 4947
>BC007559-1|AAH07559.1| 218|Homo sapiens eukaryotic translation
initiation factor 3, subunit 12 protein.
Length = 218
Score = 30.7 bits (66), Expect = 4.7
Identities = 12/37 (32%), Positives = 25/37 (67%)
Frame = +2
Query: 473 EGVDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQ 583
+ +DEN+D LE GFE+ ++K + +G++ +I++
Sbjct: 119 QALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDR 155
>BC007335-1|AAH07335.2| 117|Homo sapiens EIF3S12 protein protein.
Length = 117
Score = 30.7 bits (66), Expect = 4.7
Identities = 12/37 (32%), Positives = 25/37 (67%)
Frame = +2
Query: 473 EGVDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQ 583
+ +DEN+D LE GFE+ ++K + +G++ +I++
Sbjct: 18 QALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDR 54
>BC001031-1|AAH01031.1| 218|Homo sapiens eukaryotic translation
initiation factor 3, subunit 12 protein.
Length = 218
Score = 30.7 bits (66), Expect = 4.7
Identities = 12/37 (32%), Positives = 25/37 (67%)
Frame = +2
Query: 473 EGVDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQ 583
+ +DEN+D LE GFE+ ++K + +G++ +I++
Sbjct: 119 QALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDR 155
>AY245432-1|AAP22070.1| 218|Homo sapiens eukaryotic translation
initiation factor 3 subunit k protein.
Length = 218
Score = 30.7 bits (66), Expect = 4.7
Identities = 12/37 (32%), Positives = 25/37 (67%)
Frame = +2
Query: 473 EGVDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQ 583
+ +DEN+D LE GFE+ ++K + +G++ +I++
Sbjct: 119 QALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDR 155
>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
Length = 30000
Score = 30.7 bits (66), Expect = 4.7
Identities = 14/29 (48%), Positives = 19/29 (65%), Gaps = 1/29 (3%)
Frame = -3
Query: 580 FDVEVGHADGPGQ-SLLEDLLKPSPRLQV 497
FD E+ AD PGQ L +LL+PSP ++
Sbjct: 12343 FDAEISEADIPGQWKLKGELLRPSPTCEI 12371
>AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein.
Length = 26926
Score = 30.7 bits (66), Expect = 4.7
Identities = 14/29 (48%), Positives = 19/29 (65%), Gaps = 1/29 (3%)
Frame = -3
Query: 580 FDVEVGHADGPGQ-SLLEDLLKPSPRLQV 497
FD E+ AD PGQ L +LL+PSP ++
Sbjct: 4919 FDAEISEADIPGQWKLKGELLRPSPTCEI 4947
>AF315506-1|AAK01365.1| 218|Homo sapiens ARG134 protein protein.
Length = 218
Score = 30.7 bits (66), Expect = 4.7
Identities = 12/37 (32%), Positives = 25/37 (67%)
Frame = +2
Query: 473 EGVDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQ 583
+ +DEN+D LE GFE+ ++K + +G++ +I++
Sbjct: 119 QALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDR 155
>AF109355-1|AAQ13503.1| 218|Homo sapiens MSTP001 protein.
Length = 218
Score = 30.7 bits (66), Expect = 4.7
Identities = 12/37 (32%), Positives = 25/37 (67%)
Frame = +2
Query: 473 EGVDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQ 583
+ +DEN+D LE GFE+ ++K + +G++ +I++
Sbjct: 119 QALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDR 155
>AB019392-1|BAA76626.1| 218|Homo sapiens M9 protein.
Length = 218
Score = 30.7 bits (66), Expect = 4.7
Identities = 12/37 (32%), Positives = 25/37 (67%)
Frame = +2
Query: 473 EGVDENIDYLETWRGFEEVLKKGLTRSIGVSNFNIEQ 583
+ +DEN+D LE GFE+ ++K + +G++ +I++
Sbjct: 119 QALDENMDLLEGITGFEDSVRKFICHVVGITYQHIDR 155
>BC033329-1|AAH33329.1| 245|Homo sapiens KCTD2 protein protein.
Length = 245
Score = 29.9 bits (64), Expect = 8.3
Identities = 14/32 (43%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Frame = -2
Query: 569 SWTRRWT-W-SVPS*GPPQTLSTSPGSRYFRL 480
SWTRRW W P GPP+ +R+ RL
Sbjct: 27 SWTRRWRGWEGAPGPGPPERAGGGGAARWVRL 58
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,167,635
Number of Sequences: 237096
Number of extensions: 2083655
Number of successful extensions: 5244
Number of sequences better than 10.0: 105
Number of HSP's better than 10.0 without gapping: 4837
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5092
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7310122300
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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