Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fprWP04_F_J21
(652 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 55 2e-07
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 55 2e-07
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 55 3e-07
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 55 3e-07
AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 55 3e-07
AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 55 3e-07
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 52 2e-06
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 52 2e-06
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 52 2e-06
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 52 2e-06
BC096286-1|AAH96286.1| 437|Homo sapiens cytochrome P450, family... 52 2e-06
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 52 2e-06
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 48 2e-05
D16153-1|BAB71992.1| 132|Homo sapiens cytochrome P-450c11 protein. 38 0.023
BC001776-1|AAH01776.1| 217|Homo sapiens CYP27B1 protein protein. 36 0.13
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 36 0.13
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 36 0.13
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 36 0.13
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 36 0.13
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 36 0.13
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 36 0.13
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 36 0.13
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 36 0.13
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 36 0.13
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 32 1.5
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 32 1.5
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 32 1.5
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 32 1.5
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 32 1.5
BC039654-1|AAH39654.1| 623|Homo sapiens TBCD protein protein. 31 2.7
BC003094-1|AAH03094.1| 1192|Homo sapiens tubulin folding cofacto... 31 2.7
AL133562-1|CAB63716.1| 1050|Homo sapiens hypothetical protein pr... 31 2.7
AJ006417-1|CAA07022.1| 1248|Homo sapiens beta-tubulin cofactor D... 31 2.7
AB023205-1|BAA76832.2| 1210|Homo sapiens KIAA0988 protein protein. 31 2.7
>X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase
(P-450aldo) protein.
Length = 503
Score = 55.2 bits (127), Expect = 2e-07
Identities = 29/92 (31%), Positives = 50/92 (54%)
Frame = +2
Query: 257 GGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMKSLFLNLXXKYPAHILPEPWV 436
G ++LH + ++LGPIF L G ++V + P ++ L + +P ++ EPWV
Sbjct: 60 GYEHLHLEMHQTFQELGPIFRYNLGGP-RMVCVMLPEDVEKL-QQVDSLHPCRMILEPWV 117
Query: 437 LYEKLYGSKRGLFFMDGXDWLINRRIMNKHLL 532
Y + G K G+F ++G +W NR +N +L
Sbjct: 118 AYRQHRGHKCGVFLLNGPEWRFNRLRLNPDVL 149
>D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase
protein.
Length = 503
Score = 55.2 bits (127), Expect = 2e-07
Identities = 29/92 (31%), Positives = 50/92 (54%)
Frame = +2
Query: 257 GGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMKSLFLNLXXKYPAHILPEPWV 436
G ++LH + ++LGPIF L G ++V + P ++ L + +P ++ EPWV
Sbjct: 60 GYEHLHLEMHQTFQELGPIFRYNLGGP-RMVCVMLPEDVEKL-QQVDSLHPCRMILEPWV 117
Query: 437 LYEKLYGSKRGLFFMDGXDWLINRRIMNKHLL 532
Y + G K G+F ++G +W NR +N +L
Sbjct: 118 AYRQHRGHKCGVFLLNGPEWRFNRLRLNPDVL 149
>BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 54.8 bits (126), Expect = 3e-07
Identities = 34/132 (25%), Positives = 57/132 (43%)
Frame = +2
Query: 197 MPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMK 376
+P S P++G+ + GG K H + HK+ G IF +L G + V + P ++
Sbjct: 58 LPGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKL-GSFESVHLGSPCLLE 116
Query: 377 SLFLNLXXKYPAHILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHLLRXXSXVWL 556
+L+ YP + +PW Y GL ++G DW R K L++ + L
Sbjct: 117 ALY-RTESAYPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMKPGEVMKL 175
Query: 557 RAPIRTAVFHFI 592
I + F+
Sbjct: 176 DNKINEVLADFM 187
>BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 54.8 bits (126), Expect = 3e-07
Identities = 34/132 (25%), Positives = 57/132 (43%)
Frame = +2
Query: 197 MPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMK 376
+P S P++G+ + GG K H + HK+ G IF +L G + V + P ++
Sbjct: 58 LPGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKL-GSFESVHLGSPCLLE 116
Query: 377 SLFLNLXXKYPAHILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHLLRXXSXVWL 556
+L+ YP + +PW Y GL ++G DW R K L++ + L
Sbjct: 117 ALY-RTESAYPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMKPGEVMKL 175
Query: 557 RAPIRTAVFHFI 592
I + F+
Sbjct: 176 DNKINEVLADFM 187
>AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 448
Score = 54.8 bits (126), Expect = 3e-07
Identities = 34/132 (25%), Positives = 57/132 (43%)
Frame = +2
Query: 197 MPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMK 376
+P S P++G+ + GG K H + HK+ G IF +L G + V + P ++
Sbjct: 58 LPGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKL-GSFESVHLGSPCLLE 116
Query: 377 SLFLNLXXKYPAHILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHLLRXXSXVWL 556
+L+ YP + +PW Y GL ++G DW R K L++ + L
Sbjct: 117 ALY-RTESAYPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMKPGEVMKL 175
Query: 557 RAPIRTAVFHFI 592
I + F+
Sbjct: 176 DNKINEVLADFM 187
>AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 54.8 bits (126), Expect = 3e-07
Identities = 34/132 (25%), Positives = 57/132 (43%)
Frame = +2
Query: 197 MPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMK 376
+P S P++G+ + GG K H + HK+ G IF +L G + V + P ++
Sbjct: 58 LPGPTSWPLLGSLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKL-GSFESVHLGSPCLLE 116
Query: 377 SLFLNLXXKYPAHILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHLLRXXSXVWL 556
+L+ YP + +PW Y GL ++G DW R K L++ + L
Sbjct: 117 ALY-RTESAYPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMKPGEVMKL 175
Query: 557 RAPIRTAVFHFI 592
I + F+
Sbjct: 176 DNKINEVLADFM 187
>X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (11 Beta). ).
Length = 503
Score = 52.0 bits (119), Expect = 2e-06
Identities = 29/92 (31%), Positives = 48/92 (52%)
Frame = +2
Query: 257 GGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMKSLFLNLXXKYPAHILPEPWV 436
G ++LH + ++LGPIF L G +V + P ++ L + +P + EPWV
Sbjct: 60 GYEDLHLEVHQTFQELGPIFRYDLGG-AGMVCVMLPEDVEKL-QQVDSLHPHRMSLEPWV 117
Query: 437 LYEKLYGSKRGLFFMDGXDWLINRRIMNKHLL 532
Y + G K G+F ++G +W NR +N +L
Sbjct: 118 AYRQHRGHKCGVFLLNGPEWRFNRLRLNPEVL 149
>M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid
11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exon 9.
).
Length = 503
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/92 (30%), Positives = 49/92 (53%)
Frame = +2
Query: 257 GGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMKSLFLNLXXKYPAHILPEPWV 436
G ++LH + ++LGPIF L G ++V + P ++ L + +P ++ EPWV
Sbjct: 60 GYEHLHLEMHQTFQELGPIFRYNLGGP-RMVCVMLPEDVEKL-QQVDSLHPCRMILEPWV 117
Query: 437 LYEKLYGSKRGLFFMDGXDWLINRRIMNKHLL 532
+ G K G+F ++G +W NR +N +L
Sbjct: 118 AIRQHRGHKCGVFLLNGPEWRFNRLRLNPDVL 149
>M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein.
Length = 503
Score = 52.0 bits (119), Expect = 2e-06
Identities = 29/92 (31%), Positives = 48/92 (52%)
Frame = +2
Query: 257 GGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMKSLFLNLXXKYPAHILPEPWV 436
G ++LH + ++LGPIF L G +V + P ++ L + +P + EPWV
Sbjct: 60 GYEDLHLEVHQTFQELGPIFRYDLGG-AGMVCVMLPEDVEKL-QQVDSLHPHRMSLEPWV 117
Query: 437 LYEKLYGSKRGLFFMDGXDWLINRRIMNKHLL 532
Y + G K G+F ++G +W NR +N +L
Sbjct: 118 AYRQHRGHKCGVFLLNGPEWRFNRLRLNPEVL 149
>BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family
11, subfamily B, polypeptide 1 protein.
Length = 503
Score = 52.0 bits (119), Expect = 2e-06
Identities = 29/92 (31%), Positives = 48/92 (52%)
Frame = +2
Query: 257 GGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMKSLFLNLXXKYPAHILPEPWV 436
G ++LH + ++LGPIF L G +V + P ++ L + +P + EPWV
Sbjct: 60 GYEDLHLEVHQTFQELGPIFRYDLGG-AGMVCVMLPEDVEKL-QQVDSLHPHRMSLEPWV 117
Query: 437 LYEKLYGSKRGLFFMDGXDWLINRRIMNKHLL 532
Y + G K G+F ++G +W NR +N +L
Sbjct: 118 AYRQHRGHKCGVFLLNGPEWRFNRLRLNPEVL 149
>BC096286-1|AAH96286.1| 437|Homo sapiens cytochrome P450, family
11, subfamily B, polypeptide 1 protein.
Length = 437
Score = 52.0 bits (119), Expect = 2e-06
Identities = 29/92 (31%), Positives = 48/92 (52%)
Frame = +2
Query: 257 GGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMKSLFLNLXXKYPAHILPEPWV 436
G ++LH + ++LGPIF L G +V + P ++ L + +P + EPWV
Sbjct: 60 GYEDLHLEVHQTFQELGPIFRYDLGG-AGMVCVMLPEDVEKL-QQVDSLHPHRMSLEPWV 117
Query: 437 LYEKLYGSKRGLFFMDGXDWLINRRIMNKHLL 532
Y + G K G+F ++G +W NR +N +L
Sbjct: 118 AYRQHRGHKCGVFLLNGPEWRFNRLRLNPEVL 149
>AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome
P-450c11 protein protein.
Length = 503
Score = 52.0 bits (119), Expect = 2e-06
Identities = 29/92 (31%), Positives = 48/92 (52%)
Frame = +2
Query: 257 GGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMKSLFLNLXXKYPAHILPEPWV 436
G ++LH + ++LGPIF L G +V + P ++ L + +P + EPWV
Sbjct: 60 GYEDLHLEVHQTFQELGPIFRYDLGG-AGMVCVMLPEDVEKL-QQVDSLHPHRMSLEPWV 117
Query: 437 LYEKLYGSKRGLFFMDGXDWLINRRIMNKHLL 532
Y + G K G+F ++G +W NR +N +L
Sbjct: 118 AYRQHRGHKCGVFLLNGPEWRFNRLRLNPEVL 149
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 48.4 bits (110), Expect = 2e-05
Identities = 32/132 (24%), Positives = 55/132 (41%)
Frame = +2
Query: 197 MPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMK 376
+P S P++ + + GG K H + HK+ G IF +L G + V + P ++
Sbjct: 58 LPGPTSWPLLASLLQILWKGGLKKQHDTLVEYHKKYGKIFRMKL-GSFESVHLGSPCLLE 116
Query: 377 SLFLNLXXKYPAHILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHLLRXXSXVWL 556
+L+ P + +PW Y GL ++G DW R K L++ + L
Sbjct: 117 ALYRT--ESVPQRLEIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMKPGEVMKL 174
Query: 557 RAPIRTAVFHFI 592
I + F+
Sbjct: 175 DNKINEVLADFM 186
>D16153-1|BAB71992.1| 132|Homo sapiens cytochrome P-450c11 protein.
Length = 132
Score = 38.3 bits (85), Expect = 0.023
Identities = 23/75 (30%), Positives = 38/75 (50%)
Frame = +2
Query: 257 GGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMKSLFLNLXXKYPAHILPEPWV 436
G ++LH + ++LGPIF L G +V + P ++ L + +P + EPWV
Sbjct: 60 GYEDLHLEVHQTFQELGPIFRYDLGG-AGMVCVMLPEDVEKL-QQVDSLHPHRMSLEPWV 117
Query: 437 LYEKLYGSKRGLFFM 481
Y + G K G+F +
Sbjct: 118 AYRQHRGHKCGVFLL 132
>BC001776-1|AAH01776.1| 217|Homo sapiens CYP27B1 protein protein.
Length = 217
Score = 35.9 bits (79), Expect = 0.13
Identities = 27/122 (22%), Positives = 49/122 (40%)
Frame = +2
Query: 170 HKSLRTIXXMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLV 349
H + R++ +P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 350 FISDPTHMKSLFLNLXXKYPAHILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHL 529
+++ P ++ L L P PW + + GL +G +W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 530 LR 535
LR
Sbjct: 146 LR 147
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 35.9 bits (79), Expect = 0.13
Identities = 27/122 (22%), Positives = 49/122 (40%)
Frame = +2
Query: 170 HKSLRTIXXMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLV 349
H + R++ +P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 350 FISDPTHMKSLFLNLXXKYPAHILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHL 529
+++ P ++ L L P PW + + GL +G +W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 530 LR 535
LR
Sbjct: 146 LR 147
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 35.9 bits (79), Expect = 0.13
Identities = 27/122 (22%), Positives = 49/122 (40%)
Frame = +2
Query: 170 HKSLRTIXXMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLV 349
H + R++ +P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 350 FISDPTHMKSLFLNLXXKYPAHILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHL 529
+++ P ++ L L P PW + + GL +G +W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 530 LR 535
LR
Sbjct: 146 LR 147
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 35.9 bits (79), Expect = 0.13
Identities = 27/122 (22%), Positives = 49/122 (40%)
Frame = +2
Query: 170 HKSLRTIXXMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLV 349
H + R++ +P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 350 FISDPTHMKSLFLNLXXKYPAHILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHL 529
+++ P ++ L L P PW + + GL +G +W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 530 LR 535
LR
Sbjct: 146 LR 147
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 35.9 bits (79), Expect = 0.13
Identities = 27/122 (22%), Positives = 49/122 (40%)
Frame = +2
Query: 170 HKSLRTIXXMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLV 349
H + R++ +P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 350 FISDPTHMKSLFLNLXXKYPAHILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHL 529
+++ P ++ L L P PW + + GL +G +W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 530 LR 535
LR
Sbjct: 146 LR 147
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 35.9 bits (79), Expect = 0.13
Identities = 27/122 (22%), Positives = 49/122 (40%)
Frame = +2
Query: 170 HKSLRTIXXMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLV 349
H + R++ +P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 350 FISDPTHMKSLFLNLXXKYPAHILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHL 529
+++ P ++ L L P PW + + GL +G +W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 530 LR 535
LR
Sbjct: 146 LR 147
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 35.9 bits (79), Expect = 0.13
Identities = 27/122 (22%), Positives = 49/122 (40%)
Frame = +2
Query: 170 HKSLRTIXXMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLV 349
H + R++ +P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 350 FISDPTHMKSLFLNLXXKYPAHILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHL 529
+++ P ++ L L P PW + + GL +G +W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 530 LR 535
LR
Sbjct: 146 LR 147
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 35.9 bits (79), Expect = 0.13
Identities = 27/122 (22%), Positives = 49/122 (40%)
Frame = +2
Query: 170 HKSLRTIXXMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLV 349
H + R++ +P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 350 FISDPTHMKSLFLNLXXKYPAHILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHL 529
+++ P ++ L L P PW + + GL +G +W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 530 LR 535
LR
Sbjct: 146 LR 147
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 35.9 bits (79), Expect = 0.13
Identities = 27/122 (22%), Positives = 49/122 (40%)
Frame = +2
Query: 170 HKSLRTIXXMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLV 349
H + R++ +P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 350 FISDPTHMKSLFLNLXXKYPAHILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHL 529
+++ P ++ L L P PW + + GL +G +W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 530 LR 535
LR
Sbjct: 146 LR 147
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 35.9 bits (79), Expect = 0.13
Identities = 27/122 (22%), Positives = 49/122 (40%)
Frame = +2
Query: 170 HKSLRTIXXMPHKKSLPIIGTKFDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLV 349
H + R++ +P + + +LF GG LH+ GP++ G + V
Sbjct: 31 HSARRSLADIPGPSTPSFLA---ELFCKGGLSRLHELQVQGAAHFGPVWLASF-GTVRTV 86
Query: 350 FISDPTHMKSLFLNLXXKYPAHILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHL 529
+++ P ++ L L P PW + + GL +G +W R ++ L
Sbjct: 87 YVAAPALVEEL-LRQEGPRPERCSFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLL 145
Query: 530 LR 535
LR
Sbjct: 146 LR 147
>X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase
protein.
Length = 530
Score = 32.3 bits (70), Expect = 1.5
Identities = 24/100 (24%), Positives = 40/100 (40%)
Frame = +2
Query: 236 FDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMKSLFLNLXXKYPAH 415
F LF G LH+ + + GP++ L + + S P + + KYP
Sbjct: 69 FQLFVQGYALQLHQLQVLYKAKYGPMWMSYLGPQMHVNLASAP--LLEQVMRQEGKYPVR 126
Query: 416 ILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHLLR 535
E W + + G F +G W R+ +N+ LL+
Sbjct: 127 NDMELWKEHRDQHDLTYGPFTTEGHHWYQLRQALNQRLLK 166
>M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase
protein.
Length = 531
Score = 32.3 bits (70), Expect = 1.5
Identities = 24/100 (24%), Positives = 40/100 (40%)
Frame = +2
Query: 236 FDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMKSLFLNLXXKYPAH 415
F LF G LH+ + + GP++ L + + S P + + KYP
Sbjct: 70 FQLFVQGYALQLHQLQVLYKAKYGPMWMSYLGPQMHVNLASAP--LLEQVMRQEGKYPVR 127
Query: 416 ILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHLLR 535
E W + + G F +G W R+ +N+ LL+
Sbjct: 128 NDMELWKEHRDQHDLTYGPFTTEGHHWYQLRQALNQRLLK 167
>BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 32.3 bits (70), Expect = 1.5
Identities = 24/100 (24%), Positives = 40/100 (40%)
Frame = +2
Query: 236 FDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMKSLFLNLXXKYPAH 415
F LF G LH+ + + GP++ L + + S P + + KYP
Sbjct: 70 FQLFVQGYALQLHQLQVLYKAKYGPMWMSYLGPQMHVNLASAP--LLEQVMRQEGKYPVR 127
Query: 416 ILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHLLR 535
E W + + G F +G W R+ +N+ LL+
Sbjct: 128 NDMELWKEHRDQHDLTYGPFTTEGHHWYQLRQALNQRLLK 167
>BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 32.3 bits (70), Expect = 1.5
Identities = 24/100 (24%), Positives = 40/100 (40%)
Frame = +2
Query: 236 FDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMKSLFLNLXXKYPAH 415
F LF G LH+ + + GP++ L + + S P + + KYP
Sbjct: 70 FQLFVQGYALQLHQLQVLYKAKYGPMWMSYLGPQMHVNLASAP--LLEQVMRQEGKYPVR 127
Query: 416 ILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHLLR 535
E W + + G F +G W R+ +N+ LL+
Sbjct: 128 NDMELWKEHRDQHDLTYGPFTTEGHHWYQLRQALNQRLLK 167
>AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase
protein.
Length = 531
Score = 32.3 bits (70), Expect = 1.5
Identities = 24/100 (24%), Positives = 40/100 (40%)
Frame = +2
Query: 236 FDLFSAGGGKNLHKYIDMRHKQLGPIFYXRLTGKTKLVFISDPTHMKSLFLNLXXKYPAH 415
F LF G LH+ + + GP++ L + + S P + + KYP
Sbjct: 70 FQLFVQGYALQLHQLQVLYKAKYGPMWMSYLGPQMHVNLASAP--LLEQVMRQEGKYPVR 127
Query: 416 ILPEPWVLYEKLYGSKRGLFFMDGXDWLINRRIMNKHLLR 535
E W + + G F +G W R+ +N+ LL+
Sbjct: 128 NDMELWKEHRDQHDLTYGPFTTEGHHWYQLRQALNQRLLK 167
>BC039654-1|AAH39654.1| 623|Homo sapiens TBCD protein protein.
Length = 623
Score = 31.5 bits (68), Expect = 2.7
Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
Frame = +2
Query: 434 VLYEKLYGSK---RGLFFMDGXDWLINRRIMNKHLLRXXSXVWLRAPIRTAVFHFICNWK 604
VL EKL SK RG +DG WLIN + + HL+ S ++ +A+ +C+
Sbjct: 113 VLIEKLSLSKMPFRGDTVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSAL-AALCSEY 171
Query: 605 LXAQSGNFSPNLESE 649
+ G P ++ E
Sbjct: 172 YMKEPGEADPAIQEE 186
>BC003094-1|AAH03094.1| 1192|Homo sapiens tubulin folding cofactor D
protein.
Length = 1192
Score = 31.5 bits (68), Expect = 2.7
Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
Frame = +2
Query: 434 VLYEKLYGSK---RGLFFMDGXDWLINRRIMNKHLLRXXSXVWLRAPIRTAVFHFICNWK 604
VL EKL SK RG +DG WLIN + + HL+ S ++ +A+ +C+
Sbjct: 682 VLIEKLSLSKMPFRGDTVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSAL-AALCSEY 740
Query: 605 LXAQSGNFSPNLESE 649
+ G P ++ E
Sbjct: 741 YMKEPGEADPAIQEE 755
>AL133562-1|CAB63716.1| 1050|Homo sapiens hypothetical protein
protein.
Length = 1050
Score = 31.5 bits (68), Expect = 2.7
Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
Frame = +2
Query: 434 VLYEKLYGSK---RGLFFMDGXDWLINRRIMNKHLLRXXSXVWLRAPIRTAVFHFICNWK 604
VL EKL SK RG +DG WLIN + + HL+ S ++ +A+ +C+
Sbjct: 540 VLIEKLSLSKMPFRGDTVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSAL-AALCSEY 598
Query: 605 LXAQSGNFSPNLESE 649
+ G P ++ E
Sbjct: 599 YMKEPGEADPAIQEE 613
>AJ006417-1|CAA07022.1| 1248|Homo sapiens beta-tubulin cofactor D
protein.
Length = 1248
Score = 31.5 bits (68), Expect = 2.7
Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
Frame = +2
Query: 434 VLYEKLYGSK---RGLFFMDGXDWLINRRIMNKHLLRXXSXVWLRAPIRTAVFHFICNWK 604
VL EKL SK RG +DG WLIN + + HL+ S ++ +A+ +C+
Sbjct: 682 VLIEKLSLSKMPFRGDTVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSAL-AALCSEY 740
Query: 605 LXAQSGNFSPNLESE 649
+ G P ++ E
Sbjct: 741 YMKEPGEADPAIQEE 755
>AB023205-1|BAA76832.2| 1210|Homo sapiens KIAA0988 protein protein.
Length = 1210
Score = 31.5 bits (68), Expect = 2.7
Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
Frame = +2
Query: 434 VLYEKLYGSK---RGLFFMDGXDWLINRRIMNKHLLRXXSXVWLRAPIRTAVFHFICNWK 604
VL EKL SK RG +DG WLIN + + HL+ S ++ +A+ +C+
Sbjct: 700 VLIEKLSLSKMPFRGDTVIDGWQWLINDTLRHLHLISSHSRQQMKDAAVSAL-AALCSEY 758
Query: 605 LXAQSGNFSPNLESE 649
+ G P ++ E
Sbjct: 759 YMKEPGEADPAIQEE 773
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 89,600,376
Number of Sequences: 237096
Number of extensions: 1630975
Number of successful extensions: 3566
Number of sequences better than 10.0: 34
Number of HSP's better than 10.0 without gapping: 3517
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3557
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7253890590
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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