Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fprWP04_F_I04
(650 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9V9X4 Cluster: CG11334-PA, isoform A; n=14; Eukaryota|... 169 5e-41
UniRef50_Q4FZP2 Cluster: MGC116493 protein; n=7; Coelomata|Rep: ... 87 5e-16
UniRef50_Q0UX53 Cluster: Putative uncharacterized protein; n=1; ... 81 2e-14
UniRef50_Q9AYT7 Cluster: IDI2; n=25; Eukaryota|Rep: IDI2 - Horde... 79 7e-14
UniRef50_Q5AD59 Cluster: Potential Initiation factor 2 subunit f... 79 7e-14
UniRef50_A1CY38 Cluster: Translation initiation factor, putative... 72 1e-11
UniRef50_Q93169 Cluster: Uncharacterized protein C01G10.9; n=2; ... 68 2e-10
UniRef50_A6C0G9 Cluster: Putative translation initiation factor,... 64 2e-09
UniRef50_A7EGZ3 Cluster: Putative uncharacterized protein; n=2; ... 64 4e-09
UniRef50_Q06489 Cluster: Methylthioribose-1-phosphate isomerase;... 63 5e-09
UniRef50_UPI00006CFF79 Cluster: 5-methylthioribose kinase family... 60 6e-08
UniRef50_Q4Q0R9 Cluster: Translation initiation factor 2 subunit... 60 6e-08
UniRef50_Q67MP0 Cluster: Translation initiation factor eIF-2B al... 58 1e-07
UniRef50_Q8F2A8 Cluster: Probable methylthioribose-1-phosphate i... 54 2e-06
UniRef50_O31662 Cluster: Methylthioribose-1-phosphate isomerase;... 53 7e-06
UniRef50_O29877 Cluster: Putative translation initiation factor ... 49 8e-05
UniRef50_A1RWS6 Cluster: EIF-2B alpha/beta/delta-related unchara... 48 1e-04
UniRef50_Q55N23 Cluster: Putative uncharacterized protein; n=2; ... 46 8e-04
UniRef50_Q4JB92 Cluster: Translation initiation factor eIF-2B al... 45 0.002
UniRef50_Q0LDK7 Cluster: Putative translation initiation factor,... 43 0.006
UniRef50_A1SDR1 Cluster: EIF-2B alpha/beta/delta-related unchara... 43 0.006
UniRef50_O58433 Cluster: Putative translation initiation factor ... 42 0.013
UniRef50_A5UQK6 Cluster: Putative translation initiation factor,... 40 0.039
UniRef50_Q54R90 Cluster: Translation initiation factor eIF-2B al... 40 0.039
UniRef50_A3DN77 Cluster: EIF-2B alpha/beta/delta-related unchara... 40 0.068
UniRef50_P74497 Cluster: Probable methylthioribose-1-phosphate i... 40 0.068
UniRef50_Q8DK09 Cluster: Translation initiation factor IF-2B alp... 38 0.16
UniRef50_Q0EVX7 Cluster: Translation initiation factor IF-2B sub... 37 0.36
UniRef50_Q2LXN1 Cluster: Methylthioribose salvage protein; n=6; ... 37 0.48
UniRef50_Q1N0Y8 Cluster: Translation initiation factor IF-2B sub... 36 0.64
UniRef50_A0LIZ1 Cluster: EIF-2B alpha/beta/delta-related unchara... 36 0.64
UniRef50_Q5H060 Cluster: Initiation factor eIF-2B; n=7; Gammapro... 36 0.84
UniRef50_Q2FN46 Cluster: Putative translation initiation factor,... 36 0.84
UniRef50_Q2IH96 Cluster: Initiation factor 2B alpha/beta/delta; ... 36 1.1
UniRef50_A2QB12 Cluster: Putative uncharacterized protein; n=1; ... 36 1.1
UniRef50_Q9X013 Cluster: Probable methylthioribose-1-phosphate i... 34 3.4
UniRef50_Q8KBH1 Cluster: Translation initiation factor, eIF-2B, ... 33 5.9
UniRef50_A6GF55 Cluster: Putative translation initiation factor,... 33 5.9
UniRef50_Q9HZ65 Cluster: Probable methylthioribose-1-phosphate i... 33 5.9
UniRef50_Q6KIF6 Cluster: Expressed protein; n=1; Mycoplasma mobi... 33 7.8
UniRef50_Q6RKJ5 Cluster: Polyketide synthase; n=6; cellular orga... 33 7.8
UniRef50_A6SRQ9 Cluster: Putative uncharacterized protein; n=1; ... 33 7.8
UniRef50_Q9YE84 Cluster: Putative translation initiation factor ... 33 7.8
>UniRef50_Q9V9X4 Cluster: CG11334-PA, isoform A; n=14;
Eukaryota|Rep: CG11334-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 364
Score = 169 bits (411), Expect = 5e-41
Identities = 83/125 (66%), Positives = 99/125 (79%)
Frame = +1
Query: 199 MSLXSIKYTTGSXXXXXXXXXXXQTRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLA 378
MSL SIKY+ GS Q++Y+ VRGVEDGWKVINKMQVRGAPAIAIVGCLSLA
Sbjct: 1 MSLQSIKYSRGSLEILDQLLLPGQSKYVVVRGVEDGWKVINKMQVRGAPAIAIVGCLSLA 60
Query: 379 VELSPDNESSKKNMRQEIEGKLNYLVSARPTAVNIKLAADELINLANTLCADDSISAEIF 558
VE++P++ +KK++RQEIEGKLNYLVSARPTAVN+K+AADELI LAN L D++I
Sbjct: 61 VEINPEDFENKKSLRQEIEGKLNYLVSARPTAVNMKIAADELITLANELYKDEAIDVTQM 120
Query: 559 KERFV 573
K RF+
Sbjct: 121 KHRFL 125
>UniRef50_Q4FZP2 Cluster: MGC116493 protein; n=7; Coelomata|Rep:
MGC116493 protein - Xenopus laevis (African clawed frog)
Length = 354
Score = 86.6 bits (205), Expect = 5e-16
Identities = 49/102 (48%), Positives = 63/102 (61%)
Frame = +1
Query: 199 MSLXSIKYTTGSXXXXXXXXXXXQTRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLA 378
MSL S++Y+ GS ++ Y V GV+ G I M+VRGAPAIAIVG LSLA
Sbjct: 1 MSLESVRYSRGSLQVLNQLLLPHKSEYEPVTGVQQGADAIRTMKVRGAPAIAIVGVLSLA 60
Query: 379 VELSPDNESSKKNMRQEIEGKLNYLVSARPTAVNIKLAADEL 504
VEL+ ++ + L++LVSARPTAVN+K AADEL
Sbjct: 61 VELTTKPCQDVPSLITFVRESLHHLVSARPTAVNMKKAADEL 102
>UniRef50_Q0UX53 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 355
Score = 81.4 bits (192), Expect = 2e-14
Identities = 50/126 (39%), Positives = 67/126 (53%), Gaps = 1/126 (0%)
Frame = +1
Query: 199 MSLXSIKYTTGSXXXXXXXXXXXQTRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLA 378
M L +IKYT G Y + D W I +M+ RGAPAIAIV LSLA
Sbjct: 1 MVLQAIKYTRGQLEILDQLKLPHAEEYDHIYSSTDAWHAIKEMRTRGAPAIAIVAALSLA 60
Query: 379 VELSPDNESS-KKNMRQEIEGKLNYLVSARPTAVNIKLAADELINLANTLCADDSISAEI 555
VEL+ SS + ++ I KL YLV++RPTAVN+ AA +L + + A + S E
Sbjct: 61 VELTNMKLSSIAEEVQVFITEKLEYLVTSRPTAVNLADAAGKLKKITDEAAAREGTSGES 120
Query: 556 FKERFV 573
+E +V
Sbjct: 121 VREAYV 126
>UniRef50_Q9AYT7 Cluster: IDI2; n=25; Eukaryota|Rep: IDI2 - Hordeum
vulgare (Barley)
Length = 367
Score = 79.4 bits (187), Expect = 7e-14
Identities = 48/121 (39%), Positives = 63/121 (52%), Gaps = 1/121 (0%)
Frame = +1
Query: 202 SLXSIKYTTGSXXXXXXXXXXXQTRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAV 381
+L SI Y G+ + Y+ V+ DGW I M VRGAPAIAI LSLAV
Sbjct: 6 ALQSILYGRGALRLLDQRKLPLEEVYVDVKDSADGWNAIRDMVVRGAPAIAIAAALSLAV 65
Query: 382 ELSPDN-ESSKKNMRQEIEGKLNYLVSARPTAVNIKLAADELINLANTLCADDSISAEIF 558
E++ N + + KL YLVS+RPTAVN+ AA +L NL +T + IF
Sbjct: 66 EVNDHNFIGTPAEAASFVSKKLEYLVSSRPTAVNLSDAATKLQNLVSTTAETAKDAKSIF 125
Query: 559 K 561
+
Sbjct: 126 Q 126
>UniRef50_Q5AD59 Cluster: Potential Initiation factor 2 subunit
family protein; n=5; Saccharomycetales|Rep: Potential
Initiation factor 2 subunit family protein - Candida
albicans (Yeast)
Length = 416
Score = 79.4 bits (187), Expect = 7e-14
Identities = 41/100 (41%), Positives = 61/100 (61%), Gaps = 2/100 (2%)
Frame = +1
Query: 271 TRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMR--QEIEGKL 444
T YI + +ED +K I MQVRGAPAIAIVG S+ VE+S + S N + + + L
Sbjct: 32 TSYIPINNIEDAFKAIKLMQVRGAPAIAIVGAFSVVVEVSNYLKQSDSNQKTIKNLNDSL 91
Query: 445 NYLVSARPTAVNIKLAADELINLANTLCADDSISAEIFKE 564
NYL+++RPTAVN+ A +++ L D I +I+++
Sbjct: 92 NYLITSRPTAVNLANALNDIKQLLQKYNETDIIDEKIYQQ 131
>UniRef50_A1CY38 Cluster: Translation initiation factor, putative;
n=11; Fungi/Metazoa group|Rep: Translation initiation
factor, putative - Neosartorya fischeri (strain ATCC
1020 / DSM 3700 / NRRL 181)(Aspergillus fischerianus
(strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 387
Score = 71.7 bits (168), Expect = 1e-11
Identities = 44/105 (41%), Positives = 62/105 (59%), Gaps = 5/105 (4%)
Frame = +1
Query: 205 LXSIKYTTGSXXXXXXXXXXXQTRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVE 384
L +I+Y+ G ++I ++ ED W I +M+VRGAPAIAIV L+LA E
Sbjct: 5 LQAIRYSRGKLAIIDQLQLPYVEKFITIQTPEDAWHAIKEMRVRGAPAIAIVAALALASE 64
Query: 385 LSP----DNESS-KKNMRQEIEGKLNYLVSARPTAVNIKLAADEL 504
L+ D SS + ++ I KL+YLVS+RPTAVN+ AA +L
Sbjct: 65 LNTLIVHDKLSSGAEEVKLFIREKLDYLVSSRPTAVNLSDAARKL 109
>UniRef50_Q93169 Cluster: Uncharacterized protein C01G10.9; n=2;
Caenorhabditis|Rep: Uncharacterized protein C01G10.9 -
Caenorhabditis elegans
Length = 366
Score = 68.1 bits (159), Expect = 2e-10
Identities = 39/116 (33%), Positives = 64/116 (55%)
Frame = +1
Query: 205 LXSIKYTTGSXXXXXXXXXXXQTRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVE 384
L S+K+ + + +YI V GV D + VI MQVRGAP IA+VG L L +E
Sbjct: 25 LDSLKFDGTNLEVLDQLLLPHEFKYIPVEGVSDAFAVIKSMQVRGAPLIAVVGSLGLLLE 84
Query: 385 LSPDNESSKKNMRQEIEGKLNYLVSARPTAVNIKLAADELINLANTLCADDSISAE 552
+ +E +++ Q K+N+L+S+RPTAV+++ + + L + + D + E
Sbjct: 85 IQKASELDSESIIQ----KINFLISSRPTAVDLRNSLNGLKPILESQDYSDVVKLE 136
>UniRef50_A6C0G9 Cluster: Putative translation initiation factor,
aIF-2BI/5-methylthioribose-1- phosphate isomerase; n=1;
Planctomyces maris DSM 8797|Rep: Putative translation
initiation factor, aIF-2BI/5-methylthioribose-1-
phosphate isomerase - Planctomyces maris DSM 8797
Length = 360
Score = 64.5 bits (150), Expect = 2e-09
Identities = 33/84 (39%), Positives = 46/84 (54%)
Frame = +1
Query: 274 RYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYL 453
R I+ R VE W+ I K++VRGAPAI I + + L + + + Q + YL
Sbjct: 37 REIECRDVETVWEAIKKLRVRGAPAIGIAAAYGVVIALQTGTGNERPDFDQRLTEAATYL 96
Query: 454 VSARPTAVNIKLAADELINLANTL 525
+RPTAVN+ A D L NLA +L
Sbjct: 97 AESRPTAVNLFWALDRLQNLAASL 120
>UniRef50_A7EGZ3 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Sclerotinia sclerotiorum 1980
Length = 445
Score = 63.7 bits (148), Expect = 4e-09
Identities = 39/98 (39%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
Frame = +1
Query: 205 LXSIKYTTGSXXXXXXXXXXXQTRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVE 384
L +IKY G + Y V E+ + I M+VRGAPAIAIV L+LAVE
Sbjct: 4 LEAIKYGRGRLEVLDQLRLPHEFVYDNVSTCEEAFDSIKSMRVRGAPAIAIVAALALAVE 63
Query: 385 LSPDNESSKKNMR--QEIEGKLNYLVSARPTAVNIKLA 492
L + + SK Q I +L+YL+ +RPTAV++ A
Sbjct: 64 LHHEKDGSKTKQEAVQYINKRLDYLLGSRPTAVDLSNA 101
>UniRef50_Q06489 Cluster: Methylthioribose-1-phosphate isomerase;
n=6; Saccharomycetales|Rep: Methylthioribose-1-phosphate
isomerase - Saccharomyces cerevisiae (Baker's yeast)
Length = 411
Score = 63.3 bits (147), Expect = 5e-09
Identities = 38/105 (36%), Positives = 63/105 (60%), Gaps = 12/105 (11%)
Frame = +1
Query: 271 TRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSL--AVELSPDNESSK----------K 414
T+Y+ + ++DG+ VI MQVRGAPAIAIVG LS+ V+L N +S +
Sbjct: 30 TKYVPIHTIDDGYSVIKSMQVRGAPAIAIVGSLSVLTEVQLIKHNPTSDVATLYSLVNWE 89
Query: 415 NMRQEIEGKLNYLVSARPTAVNIKLAADELINLANTLCADDSISA 549
+ + + +L++L+S+RPTAVN+ ++ L+ + N L + + A
Sbjct: 90 STKTVLNKRLDFLLSSRPTAVNL---SNSLVEIKNILKSSSDLKA 131
>UniRef50_UPI00006CFF79 Cluster: 5-methylthioribose kinase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
5-methylthioribose kinase family protein - Tetrahymena
thermophila SB210
Length = 779
Score = 59.7 bits (138), Expect = 6e-08
Identities = 29/69 (42%), Positives = 43/69 (62%)
Frame = +1
Query: 280 IKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLVS 459
I++ +ED WKVI M VRGAP IA+V L EL + S + +R+ + + YL +
Sbjct: 30 IRINTIEDAWKVIKDMNVRGAPLIAVVATQGLRNELFNRDFKSVEELRKYVLQAVEYLRT 89
Query: 460 ARPTAVNIK 486
+RPTAVN++
Sbjct: 90 SRPTAVNLQ 98
>UniRef50_Q4Q0R9 Cluster: Translation initiation factor 2 subunit,
putative; n=7; Trypanosomatidae|Rep: Translation
initiation factor 2 subunit, putative - Leishmania major
Length = 506
Score = 59.7 bits (138), Expect = 6e-08
Identities = 35/98 (35%), Positives = 54/98 (55%), Gaps = 4/98 (4%)
Frame = +1
Query: 202 SLXSIKYTTGSXXXXXXXXXXXQTRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAV 381
+L SIKYT GS +T + V VED W I +M+VRGAPAIA+ L +AV
Sbjct: 140 TLESIKYTPGSLRLLDQRKLPLETVFDDVLTVEDIWSAIKEMRVRGAPAIAVSAALGIAV 199
Query: 382 ELSPDNESSKKNMRQEIEGKL----NYLVSARPTAVNI 483
+ + +E++ L ++++++RPTAVN+
Sbjct: 200 ATQRKAANGELKSGREVQTFLLTSCDFVMTSRPTAVNL 237
>UniRef50_Q67MP0 Cluster: Translation initiation factor eIF-2B alpha
subunit; n=26; Bacteria|Rep: Translation initiation
factor eIF-2B alpha subunit - Symbiobacterium
thermophilum
Length = 359
Score = 58.4 bits (135), Expect = 1e-07
Identities = 28/79 (35%), Positives = 44/79 (55%)
Frame = +1
Query: 268 QTRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLN 447
+TRY+++ E+ W+ I ++VRGAPAI I + L + + + ++ E
Sbjct: 28 ETRYLRLTTPEETWEAIRSLRVRGAPAIGIAAAMGLYLGVKGSEAADFEDFYHEFRQVKA 87
Query: 448 YLVSARPTAVNIKLAADEL 504
YL SARPTAVN+ A D +
Sbjct: 88 YLASARPTAVNLFWALDRM 106
>UniRef50_Q8F2A8 Cluster: Probable methylthioribose-1-phosphate
isomerase; n=4; Leptospira|Rep: Probable
methylthioribose-1-phosphate isomerase - Leptospira
interrogans
Length = 364
Score = 54.4 bits (125), Expect = 2e-06
Identities = 32/77 (41%), Positives = 45/77 (58%)
Frame = +1
Query: 271 TRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNY 450
T YI + +ED I +M VRGAPAIAI G + + N K E++ KL+
Sbjct: 28 TSYITAKTLEDCIFAIREMVVRGAPAIAITGAFGITLYW---NSLVSKPSFSELKLKLSE 84
Query: 451 LVSARPTAVNIKLAADE 501
L+ +RPTAVN++LA +E
Sbjct: 85 LLESRPTAVNLRLAIEE 101
>UniRef50_O31662 Cluster: Methylthioribose-1-phosphate isomerase;
n=17; Bacillaceae|Rep: Methylthioribose-1-phosphate
isomerase - Bacillus subtilis
Length = 353
Score = 52.8 bits (121), Expect = 7e-06
Identities = 27/79 (34%), Positives = 42/79 (53%)
Frame = +1
Query: 268 QTRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLN 447
+T Y+++ ED + I ++VRGAPAI I LA+ + R+ +E
Sbjct: 29 ETEYLELTTKEDVFDAIVTLKVRGAPAIGITAAFGLALAAKDIETDNVTEFRRRLEDIKQ 88
Query: 448 YLVSARPTAVNIKLAADEL 504
YL S+RPTA+N+ A + L
Sbjct: 89 YLNSSRPTAINLSWALERL 107
>UniRef50_O29877 Cluster: Putative translation initiation factor
eIF-2B subunit 1; n=10; Archaea|Rep: Putative
translation initiation factor eIF-2B subunit 1 -
Archaeoglobus fulgidus
Length = 339
Score = 49.2 bits (112), Expect = 8e-05
Identities = 24/79 (30%), Positives = 42/79 (53%)
Frame = +1
Query: 280 IKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLVS 459
I+ R VE+ I K+ VRGAPA+ G +A+ + +++ ++ ++L S
Sbjct: 25 IECRNVEELADAIKKLAVRGAPALEAAGAYGIALAAREREFADVDELKEHLKKAADFLAS 84
Query: 460 ARPTAVNIKLAADELINLA 516
RPTAVN+ + + +N A
Sbjct: 85 TRPTAVNLFVGIERALNAA 103
>UniRef50_A1RWS6 Cluster: EIF-2B alpha/beta/delta-related
uncharacterized proteins; n=1; Thermofilum pendens Hrk
5|Rep: EIF-2B alpha/beta/delta-related uncharacterized
proteins - Thermofilum pendens (strain Hrk 5)
Length = 345
Score = 48.4 bits (110), Expect = 1e-04
Identities = 30/118 (25%), Positives = 54/118 (45%)
Frame = +1
Query: 211 SIKYTTGSXXXXXXXXXXXQTRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELS 390
+I++ G + YI+ E K I M++RGAPAI + ++A+
Sbjct: 7 TIEWVNGRVRLINQKLLPHRLEYIETSSWERVVKAIKDMEIRGAPAIGVAAAYAVALFAV 66
Query: 391 PDNESSKKNMRQEIEGKLNYLVSARPTAVNIKLAADELINLANTLCADDSISAEIFKE 564
+ + +E+E + SARPTAVN+ A + ++ +A T + + I +E
Sbjct: 67 NFPGENLEAFMKELERVAGVVKSARPTAVNLSWAVNRVVRVAMTATSVEEARKVILEE 124
>UniRef50_Q55N23 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 393
Score = 46.0 bits (104), Expect = 8e-04
Identities = 28/81 (34%), Positives = 45/81 (55%), Gaps = 5/81 (6%)
Frame = +1
Query: 277 YIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELSP-----DNESSKKNMRQEIEGK 441
++ V E+ + I M++RGAPAIA + L+L LS + SS ++ +
Sbjct: 41 WMPVSTPEEAFDAIKTMRIRGAPAIASLAALTLRSYLSSSSSPVSSSSSSSDVISWVGQT 100
Query: 442 LNYLVSARPTAVNIKLAADEL 504
++YL S+RPTAVN+ A D +
Sbjct: 101 IDYLQSSRPTAVNLGEAMDRI 121
>UniRef50_Q4JB92 Cluster: Translation initiation factor eIF-2B alpha
subunit; n=8; Thermoprotei|Rep: Translation initiation
factor eIF-2B alpha subunit - Sulfolobus acidocaldarius
Length = 367
Score = 44.8 bits (101), Expect = 0.002
Identities = 29/83 (34%), Positives = 43/83 (51%)
Frame = +1
Query: 277 YIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLV 456
Y+ V VE+ I M+VRGAPAI I + + + D+ S +K + + K L
Sbjct: 46 YVDVTKVEEVSDAIRTMKVRGAPAIGITAGYGMVLAIQ-DSISLEKAISDLTKAK-KILD 103
Query: 457 SARPTAVNIKLAADELINLANTL 525
+RPTAVN+ A ++N A L
Sbjct: 104 ESRPTAVNLMWATSRMLNKAKDL 126
>UniRef50_Q0LDK7 Cluster: Putative translation initiation factor,
aIF-2BI/5-methylthioribose-1- phosphate isomerase; n=2;
Chloroflexi (class)|Rep: Putative translation initiation
factor, aIF-2BI/5-methylthioribose-1- phosphate
isomerase - Herpetosiphon aurantiacus ATCC 23779
Length = 358
Score = 43.2 bits (97), Expect = 0.006
Identities = 22/88 (25%), Positives = 44/88 (50%)
Frame = +1
Query: 310 KVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLVSARPTAVNIKL 489
+ I MQVRGAPAI I +A+ + + +++ L + RPTA+N+
Sbjct: 42 EAIRSMQVRGAPAIGITAAYGMALAAQRSTAQTSSKLLEKLAKAKALLDATRPTAINLAW 101
Query: 490 AADELINLANTLCADDSISAEIFKERFV 573
A ++++A A+ ++ + ++R +
Sbjct: 102 ATQRMLDVAQ---ANHTLEVDQLRQRLL 126
>UniRef50_A1SDR1 Cluster: EIF-2B alpha/beta/delta-related
uncharacterized proteins; n=3; Actinomycetales|Rep:
EIF-2B alpha/beta/delta-related uncharacterized proteins
- Nocardioides sp. (strain BAA-499 / JS614)
Length = 344
Score = 43.2 bits (97), Expect = 0.006
Identities = 25/79 (31%), Positives = 41/79 (51%)
Frame = +1
Query: 268 QTRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLN 447
+ RY+ V V+ I + VRGAPA+ VG L + V + + R ++E ++
Sbjct: 25 EERYLDVDTVDALVAAIQSLAVRGAPALGAVGALGVVVAMRQAEREGWDDERLQVE--VD 82
Query: 448 YLVSARPTAVNIKLAADEL 504
+ ARPTAVN+ D++
Sbjct: 83 RIRLARPTAVNLAWGVDQV 101
>UniRef50_O58433 Cluster: Putative translation initiation factor
eIF-2B subunit 1; n=4; Thermococcaceae|Rep: Putative
translation initiation factor eIF-2B subunit 1 -
Pyrococcus horikoshii
Length = 364
Score = 41.9 bits (94), Expect = 0.013
Identities = 30/98 (30%), Positives = 41/98 (41%), Gaps = 2/98 (2%)
Frame = +1
Query: 283 KVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLVSA 462
K VE+ + I M VRGAPAI LA+ +K+ E L +
Sbjct: 40 KFSKVEEVAEAIKNMTVRGAPAIGAAAGFGLALYAETSKAKTKEEFLDGFEKAYEILKNT 99
Query: 463 RPTAVNIKLAADELINLANTLCAD--DSISAEIFKERF 570
RPTAVN+ A + + L D D I I +E +
Sbjct: 100 RPTAVNLFWALNRIKKLVEEHSEDPLDEIKRLIVQEAY 137
>UniRef50_A5UQK6 Cluster: Putative translation initiation factor,
aIF-2BI family; n=5; Bacteria|Rep: Putative translation
initiation factor, aIF-2BI family - Roseiflexus sp. RS-1
Length = 353
Score = 40.3 bits (90), Expect = 0.039
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 3/89 (3%)
Frame = +1
Query: 268 QTRYIKVRGVEDGWKVINKMQVRGAPAI---AIVGCLSLAVELSPDNESSKKNMRQEIEG 438
+TR ++ VED I MQ+RGAPAI A G A + D + +
Sbjct: 26 ETRIVRCAAVEDVAYAIRTMQIRGAPAIGCAAAYGMALAACSAAHDAVGDVARIYARLAE 85
Query: 439 KLNYLVSARPTAVNIKLAADELINLANTL 525
L + RPTAVN+ A ++ A +L
Sbjct: 86 AKALLDAQRPTAVNLSWATRRVLERAQSL 114
>UniRef50_Q54R90 Cluster: Translation initiation factor eIF-2B alpha
subunit; n=1; Dictyostelium discoideum AX4|Rep:
Translation initiation factor eIF-2B alpha subunit -
Dictyostelium discoideum AX4
Length = 346
Score = 40.3 bits (90), Expect = 0.039
Identities = 29/89 (32%), Positives = 43/89 (48%)
Frame = +1
Query: 298 EDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLVSARPTAV 477
ED I ++ VRGAP I + +SL + + + +K +EI L +RPTAV
Sbjct: 39 EDMITFIKQLSVRGAPLIGVAASMSLYNHILYNPQLTK----EEIVKVSQELRESRPTAV 94
Query: 478 NIKLAADELINLANTLCADDSISAEIFKE 564
N+ A DE++ L + SA F E
Sbjct: 95 NLMFAIDEMMQLKEGNVENRDYSATRFGE 123
>UniRef50_A3DN77 Cluster: EIF-2B alpha/beta/delta-related
uncharacterized proteins; n=1; Staphylothermus marinus
F1|Rep: EIF-2B alpha/beta/delta-related uncharacterized
proteins - Staphylothermus marinus (strain ATCC 43588 /
DSM 3639 / F1)
Length = 356
Score = 39.5 bits (88), Expect = 0.068
Identities = 19/58 (32%), Positives = 32/58 (55%)
Frame = +1
Query: 310 KVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLVSARPTAVNI 483
K I +M++RGAPAI + L++A + +E++ +N L + RPTA N+
Sbjct: 47 KAIIEMEIRGAPAIGVAAALAIASYAYKVKTRDIDSFYREVDSAINILWNTRPTAHNL 104
>UniRef50_P74497 Cluster: Probable methylthioribose-1-phosphate
isomerase; n=28; cellular organisms|Rep: Probable
methylthioribose-1-phosphate isomerase - Synechocystis
sp. (strain PCC 6803)
Length = 351
Score = 39.5 bits (88), Expect = 0.068
Identities = 21/67 (31%), Positives = 34/67 (50%)
Frame = +1
Query: 316 INKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLVSARPTAVNIKLAA 495
I M VRGAPAI + + + + + ++E + L RPTAVN+ A
Sbjct: 47 IKSMVVRGAPAIGVAAAYGMYLGARRIQTTELREFVVQLEFVADQLRQTRPTAVNLFWAI 106
Query: 496 DELINLA 516
D+++N+A
Sbjct: 107 DQMLNVA 113
>UniRef50_Q8DK09 Cluster: Translation initiation factor IF-2B alpha
subunit; n=6; Cyanobacteria|Rep: Translation initiation
factor IF-2B alpha subunit - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 355
Score = 38.3 bits (85), Expect = 0.16
Identities = 22/67 (32%), Positives = 31/67 (46%)
Frame = +1
Query: 316 INKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLVSARPTAVNIKLAA 495
I M VRGAPAI + + + S ++ +E + L RPTAVN+ A
Sbjct: 47 IRTMIVRGAPAIGVAAAFGMVLGAREYRGSDREGFLIHLENIASQLRQTRPTAVNLFWAI 106
Query: 496 DELINLA 516
D L+ A
Sbjct: 107 DRLLAAA 113
>UniRef50_Q0EVX7 Cluster: Translation initiation factor IF-2B
subunit alpha; n=1; Mariprofundus ferrooxydans PV-1|Rep:
Translation initiation factor IF-2B subunit alpha -
Mariprofundus ferrooxydans PV-1
Length = 317
Score = 37.1 bits (82), Expect = 0.36
Identities = 27/69 (39%), Positives = 34/69 (49%)
Frame = +1
Query: 298 EDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLVSARPTAV 477
ED I MQ+RGAP+I L LA+ S D R+ + L S RPTAV
Sbjct: 15 EDVALAIETMQIRGAPSIGAAAALGLALAWSVDR-------RRFSDFWLPRFRSTRPTAV 67
Query: 478 NIKLAADEL 504
N+ A DE+
Sbjct: 68 NLFHACDEM 76
>UniRef50_Q2LXN1 Cluster: Methylthioribose salvage protein; n=6;
Bacteria|Rep: Methylthioribose salvage protein -
Syntrophus aciditrophicus (strain SB)
Length = 367
Score = 36.7 bits (81), Expect = 0.48
Identities = 21/79 (26%), Positives = 35/79 (44%)
Frame = +1
Query: 268 QTRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLN 447
+ RY+ E+ I + VRGAPAI + + +A+ + S + E +
Sbjct: 26 EERYLTCTRFEEVLTAIRDLTVRGAPAIGVASAMGIALGALSLPDDSPEAFCNGFEALCD 85
Query: 448 YLVSARPTAVNIKLAADEL 504
ARPTA N+ A + +
Sbjct: 86 RFAQARPTARNLFWAVERM 104
>UniRef50_Q1N0Y8 Cluster: Translation initiation factor IF-2B
subunit alpha; n=1; Oceanobacter sp. RED65|Rep:
Translation initiation factor IF-2B subunit alpha -
Oceanobacter sp. RED65
Length = 358
Score = 36.3 bits (80), Expect = 0.64
Identities = 24/79 (30%), Positives = 39/79 (49%)
Frame = +1
Query: 268 QTRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLN 447
+ +YI+ I M VRGAPAI I +LA+ + K R + + +N
Sbjct: 31 EIKYIECSDASAVANAIKNMVVRGAPAIGISAAYALAL------AARKLGPRGDYKSIIN 84
Query: 448 YLVSARPTAVNIKLAADEL 504
L ++RPTA+N+ A + +
Sbjct: 85 ELSASRPTAINLFWAIERV 103
>UniRef50_A0LIZ1 Cluster: EIF-2B alpha/beta/delta-related
uncharacterized proteins; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: EIF-2B alpha/beta/delta-related
uncharacterized proteins - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 349
Score = 36.3 bits (80), Expect = 0.64
Identities = 17/63 (26%), Positives = 31/63 (49%)
Frame = +1
Query: 316 INKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLVSARPTAVNIKLAA 495
I M +RGAPA+ + G ++LA+ + + + + + +ARPT N+ A
Sbjct: 43 IKNMAIRGAPAVGVAGAMALALGAVLIQAADARTFKSKFARLCRQVRTARPTGRNLGWAV 102
Query: 496 DEL 504
D +
Sbjct: 103 DRI 105
>UniRef50_Q5H060 Cluster: Initiation factor eIF-2B; n=7;
Gammaproteobacteria|Rep: Initiation factor eIF-2B -
Xanthomonas oryzae pv. oryzae
Length = 449
Score = 35.9 bits (79), Expect = 0.84
Identities = 24/75 (32%), Positives = 35/75 (46%)
Frame = +1
Query: 310 KVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLVSARPTAVNIKL 489
+ I+ + VRGAPAI I +A+ Q++E L L +ARPTAVN+
Sbjct: 145 EAIHSLAVRGAPAIGIAAGWGVALAARDIAADDGNAALQKLEPALLRLNAARPTAVNLAW 204
Query: 490 AADELINLANTLCAD 534
A + + AD
Sbjct: 205 ALMRMRRVLGAAGAD 219
>UniRef50_Q2FN46 Cluster: Putative translation initiation factor,
aIF-2BI/5-methylthioribose-1- phosphate isomerase; n=2;
Methanomicrobiales|Rep: Putative translation initiation
factor, aIF-2BI/5-methylthioribose-1- phosphate
isomerase - Methanospirillum hungatei (strain JF-1 / DSM
864)
Length = 354
Score = 35.9 bits (79), Expect = 0.84
Identities = 19/73 (26%), Positives = 33/73 (45%)
Frame = +1
Query: 289 RGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLVSARP 468
R + D + I ++ +RGAPA+ G +A+ S ++ + L RP
Sbjct: 36 RTIPDLAEAIKRLGIRGAPALGCAGGCGVALSALITKADSLPEFLDQVGSDADLLRKTRP 95
Query: 469 TAVNIKLAADELI 507
TAVN+ D ++
Sbjct: 96 TAVNLFYGIDHVL 108
>UniRef50_Q2IH96 Cluster: Initiation factor 2B alpha/beta/delta;
n=4; Bacteria|Rep: Initiation factor 2B alpha/beta/delta
- Anaeromyxobacter dehalogenans (strain 2CP-C)
Length = 339
Score = 35.5 bits (78), Expect = 1.1
Identities = 23/75 (30%), Positives = 37/75 (49%)
Frame = +1
Query: 268 QTRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLN 447
+ R++++ E I + VRGAPAI + +LAV E+ + + + +
Sbjct: 30 EERWLELSTAEAVAAAIQDLTVRGAPAIGVAAAYALAV------EARRGAGPERLRAAAD 83
Query: 448 YLVSARPTAVNIKLA 492
L ARPTAVN+ A
Sbjct: 84 LLARARPTAVNLAWA 98
>UniRef50_A2QB12 Cluster: Putative uncharacterized protein; n=1;
Aspergillus niger|Rep: Putative uncharacterized protein
- Aspergillus niger
Length = 211
Score = 35.5 bits (78), Expect = 1.1
Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Frame = -2
Query: 493 LPILYLQLLAWQTPDS*VYLRSLASCFFLKIHCQVIIQRLVI--SNPLWLWLVLHGPAFY 320
LP ++L L W SLA+ F + +HC + + +LV S PL++WL Y
Sbjct: 45 LPCIFLPLTPWSCGSLDELYPSLANIFDICLHCVLFVLQLVFLASLPLFIWLPFGVYVLY 104
Query: 319 LL 314
+L
Sbjct: 105 IL 106
>UniRef50_Q9X013 Cluster: Probable methylthioribose-1-phosphate
isomerase; n=29; cellular organisms|Rep: Probable
methylthioribose-1-phosphate isomerase - Thermotoga
maritima
Length = 343
Score = 33.9 bits (74), Expect = 3.4
Identities = 21/76 (27%), Positives = 36/76 (47%)
Frame = +1
Query: 277 YIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLV 456
Y++ + E+ I +M VRGAPAI + + L S + ++++ L
Sbjct: 29 YVECKTHEEVAHAIKEMIVRGAPAIGVAAAFGYVLGLRDYKTGSLTDWMKQVK---ETLA 85
Query: 457 SARPTAVNIKLAADEL 504
RPTAVN+ A + +
Sbjct: 86 RTRPTAVNLFWALNRM 101
>UniRef50_Q8KBH1 Cluster: Translation initiation factor, eIF-2B,
putative; n=10; Chlorobiaceae|Rep: Translation
initiation factor, eIF-2B, putative - Chlorobium tepidum
Length = 354
Score = 33.1 bits (72), Expect = 5.9
Identities = 21/115 (18%), Positives = 52/115 (45%)
Frame = +1
Query: 205 LXSIKYTTGSXXXXXXXXXXXQTRYIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVE 384
+ +I + G+ Q +++ + ++ + I + VRGAP I ++ +
Sbjct: 2 IDAISFKNGTFRYLDQRFLPLQEIHVETKNHQEAIEAIKTLAVRGAPLIGASAGYTVVLG 61
Query: 385 LSPDNESSKKNMRQEIEGKLNYLVSARPTAVNIKLAADELINLANTLCADDSISA 549
++ + K + + + + ++RPTAVN+ A ++ + + +DS+ A
Sbjct: 62 IN-EYTGDKAGFPEYFKNLIAEVNASRPTAVNLFFATKKMQEVYDANFENDSLEA 115
>UniRef50_A6GF55 Cluster: Putative translation initiation factor,
aIF-2BI family protein; n=1; Plesiocystis pacifica
SIR-1|Rep: Putative translation initiation factor,
aIF-2BI family protein - Plesiocystis pacifica SIR-1
Length = 358
Score = 33.1 bits (72), Expect = 5.9
Identities = 22/75 (29%), Positives = 36/75 (48%)
Frame = +1
Query: 277 YIKVRGVEDGWKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLV 456
++++R +E I + VRGAPAI L V LS + + + L
Sbjct: 40 WVELRELEPIAHAIETLTVRGAPAIGCAAAYGLYV-LSLAFPDDPEAFQAAFDAAAVRLA 98
Query: 457 SARPTAVNIKLAADE 501
+ RPTAVN+ +A ++
Sbjct: 99 NTRPTAVNLFVAIEQ 113
>UniRef50_Q9HZ65 Cluster: Probable methylthioribose-1-phosphate
isomerase; n=34; Proteobacteria|Rep: Probable
methylthioribose-1-phosphate isomerase - Pseudomonas
aeruginosa
Length = 358
Score = 33.1 bits (72), Expect = 5.9
Identities = 21/65 (32%), Positives = 31/65 (47%)
Frame = +1
Query: 310 KVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLVSARPTAVNIKL 489
K I M VRGAPAI I + + + + + R +E L +RPTAVN+
Sbjct: 46 KAIRDMVVRGAPAIGISAAYGIVLG-ARARLAQGGDWRAALEEDFRLLADSRPTAVNLFW 104
Query: 490 AADEL 504
A + +
Sbjct: 105 ALNRM 109
>UniRef50_Q6KIF6 Cluster: Expressed protein; n=1; Mycoplasma
mobile|Rep: Expressed protein - Mycoplasma mobile
Length = 334
Score = 32.7 bits (71), Expect = 7.8
Identities = 18/76 (23%), Positives = 39/76 (51%), Gaps = 5/76 (6%)
Frame = +1
Query: 307 WKVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLV-----SARPT 471
WK+ + A IAIV ++ + + + ES+ ++++EI+ K+ + + PT
Sbjct: 7 WKIFTSTSISIASIIAIVAPTTVVLVSNSNTESTLNSLKKEIQDKIEDRIIRGSDTILPT 66
Query: 472 AVNIKLAADELINLAN 519
A+N+ + ++ L N
Sbjct: 67 ALNLTNLRNNILGLPN 82
>UniRef50_Q6RKJ5 Cluster: Polyketide synthase; n=6; cellular
organisms|Rep: Polyketide synthase - Botrytis cinerea
(Noble rot fungus) (Botryotinia fuckeliana)
Length = 4015
Score = 32.7 bits (71), Expect = 7.8
Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = -2
Query: 532 QHKVYLPNLSAHQLPILYLQLLAWQTPDS*VYLRSLASCFFLKIHCQVIIQRLV--ISNP 359
Q ++ L N+ ++ L ++ WQT R + + H ++ L +
Sbjct: 2165 QDEISLQNIQNSRVAYAALNIVNWQTSSVQALQRPIDHGLIFRDHVTYLLFGLAGELGQS 2224
Query: 358 LWLWLVLHGPAFYLLLSNHPQ 296
L W+VLHG L+ S +P+
Sbjct: 2225 LCSWMVLHGARHVLIASRNPK 2245
>UniRef50_A6SRQ9 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 3040
Score = 32.7 bits (71), Expect = 7.8
Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Frame = -2
Query: 532 QHKVYLPNLSAHQLPILYLQLLAWQTPDS*VYLRSLASCFFLKIHCQVIIQRLV--ISNP 359
Q ++ L N+ ++ L ++ WQT R + + H ++ L +
Sbjct: 2077 QDEISLQNIQNSRVAYAALNIVNWQTSSVQALQRPIDHGLIFRDHVTYLLFGLAGELGQS 2136
Query: 358 LWLWLVLHGPAFYLLLSNHPQ 296
L W+VLHG L+ S +P+
Sbjct: 2137 LCSWMVLHGARHVLIASRNPK 2157
>UniRef50_Q9YE84 Cluster: Putative translation initiation factor
eIF-2B subunit 1; n=4; Thermoprotei|Rep: Putative
translation initiation factor eIF-2B subunit 1 -
Aeropyrum pernix
Length = 370
Score = 32.7 bits (71), Expect = 7.8
Identities = 16/58 (27%), Positives = 28/58 (48%)
Frame = +1
Query: 310 KVINKMQVRGAPAIAIVGCLSLAVELSPDNESSKKNMRQEIEGKLNYLVSARPTAVNI 483
+ I M++RGAPAI + +LA+ + + + + + S RPTA N+
Sbjct: 58 RAIVDMEIRGAPAIGVAAAYALALAAAEAASRGGEGFIEALSEARREIESTRPTAYNL 115
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 525,745,303
Number of Sequences: 1657284
Number of extensions: 9764694
Number of successful extensions: 21915
Number of sequences better than 10.0: 43
Number of HSP's better than 10.0 without gapping: 21451
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 21890
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 48760335122
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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