Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fprWP04_F_D06
(547 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 87 3e-17
BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 86 7e-17
BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 86 7e-17
M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate deh... 78 2e-14
U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogen... 64 4e-10
BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5... 64 4e-10
AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase p... 64 4e-10
BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta... 61 2e-09
AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimer... 61 2e-09
AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein. 61 2e-09
AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol dehydrog... 60 7e-09
L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid dehydro... 59 9e-09
L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid de... 59 9e-09
BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta... 59 9e-09
BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta... 59 9e-09
AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta... 59 9e-09
AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta... 59 9e-09
U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha hydroxy... 59 1e-08
U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific de... 57 5e-08
BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase... 56 6e-08
AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein. 56 6e-08
AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase p... 56 6e-08
AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-depende... 56 6e-08
AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-depende... 56 6e-08
AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-depende... 56 6e-08
AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid ... 56 6e-08
AF295380-1|AAL37037.1| 319|Homo sapiens short-chain dehydrogena... 56 6e-08
AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase h... 56 6e-08
AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase p... 56 6e-08
AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein. 56 6e-08
U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 56 1e-07
BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain dehy... 55 1e-07
BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain dehy... 55 1e-07
AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase s... 55 1e-07
X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for ... 54 3e-07
U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 54 3e-07
M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 54 3e-07
M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental... 54 3e-07
M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol... 54 3e-07
BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta... 54 3e-07
BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta... 54 3e-07
U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 53 6e-07
U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid de... 53 8e-07
EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta... 53 8e-07
BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta... 53 8e-07
BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta... 53 8e-07
BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4 pr... 49 9e-06
BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4 pr... 49 9e-06
AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens ... 49 9e-06
X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein. 47 5e-05
BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma var... 47 5e-05
BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma var... 47 5e-05
AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer seg... 47 5e-05
DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retin... 42 0.001
BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase... 42 0.001
AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein. 42 0.001
AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens ... 42 0.001
AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol... 42 0.001
AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein prot... 42 0.001
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 41 0.003
BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta... 40 0.004
BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta... 40 0.004
BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta... 40 0.004
BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta... 40 0.004
AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein. 40 0.004
AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens ... 40 0.004
AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen HD-C... 40 0.004
AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain deh... 40 0.004
Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta) ... 40 0.006
Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta) ... 40 0.006
U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide bind... 40 0.006
U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol dehyd... 40 0.006
M29037-1|AAB17014.1| 214|Homo sapiens 17 beta-hydroxysteroid de... 40 0.006
CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein. 40 0.006
BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta... 40 0.006
BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta... 40 0.006
AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain ty... 40 0.006
AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain... 40 0.006
AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid d... 40 0.006
AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid d... 40 0.006
U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein. 40 0.008
BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal dehyd... 40 0.008
BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal dehyd... 40 0.008
BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein. 40 0.008
BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase... 40 0.008
AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens ... 40 0.008
AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol deh... 40 0.008
BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein. 38 0.017
X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid deh... 38 0.023
U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid deh... 38 0.023
CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein. 38 0.023
BT019371-1|AAV38178.1| 260|Homo sapiens hydroxysteroid (17-beta... 38 0.023
BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta... 38 0.023
BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta... 38 0.023
BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta... 38 0.023
AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta... 38 0.023
AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta... 38 0.023
AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase h... 38 0.023
AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens ... 38 0.023
AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid ... 38 0.023
AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain deh... 37 0.053
BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid dehydrog... 36 0.070
BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid dehydrog... 36 0.070
AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein. 36 0.070
AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-l... 36 0.070
AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens ... 36 0.070
AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-l... 36 0.070
CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein. 35 0.16
BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid dehydrog... 35 0.16
BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid dehydrog... 35 0.16
BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 1... 35 0.16
BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 1... 35 0.16
BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein. 35 0.16
BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 1... 35 0.16
AY046280-1|AAK91586.1| 132|Homo sapiens hydroxysteroid dehydrog... 35 0.16
AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protei... 35 0.16
AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated shor... 35 0.16
AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein. 35 0.16
DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 1... 35 0.21
BC026024-1|AAH26024.1| 312|Homo sapiens DHRS12 protein protein. 35 0.21
CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein. 34 0.37
BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase... 34 0.37
BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase... 34 0.37
BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase... 34 0.37
AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein. 34 0.37
AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein. 34 0.37
AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens ... 33 0.49
CR381696-3|CAI95411.1| 266|Homo sapiens dehydrogenase/reductase... 33 0.65
CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase... 33 0.65
BX649443-3|CAI95432.1| 266|Homo sapiens dehydrogenase/reductase... 33 0.65
BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase... 33 0.65
BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase... 33 0.65
BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein. 33 0.65
AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein. 33 0.65
AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase... 33 0.65
BC009825-1|AAH09825.1| 271|Homo sapiens dehydrogenase/reductase... 32 1.5
AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein. 32 1.5
AL162377-1|CAI13427.1| 242|Homo sapiens dehydrogenase/reductase... 32 1.5
AL136525-2|CAH70586.1| 242|Homo sapiens dehydrogenase/reductase... 32 1.5
AK126701-1|BAC86649.1| 173|Homo sapiens protein ( Homo sapiens ... 32 1.5
AK023701-1|BAB14646.1| 242|Homo sapiens protein ( Homo sapiens ... 32 1.5
BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 1... 31 2.0
AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic reticulum-a... 31 2.0
BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 31 3.5
BC051291-1|AAH51291.1| 305|Homo sapiens RDH11 protein protein. 31 3.5
BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 31 3.5
AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein. 31 3.5
AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA pro... 31 3.5
Z95114-1|CAI17910.1| 451|Homo sapiens apolipoprotein L, 2 protein. 30 4.6
Z82215-1|CAI22437.1| 451|Homo sapiens apolipoprotein L, 2 protein. 30 4.6
U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein. 30 4.6
BC004395-1|AAH04395.1| 337|Homo sapiens apolipoprotein L, 2 pro... 30 4.6
AL031426-1|CAI17902.1| 451|Homo sapiens apolipoprotein L, 2 pro... 30 4.6
AK056938-1|BAB71315.1| 337|Homo sapiens protein ( Homo sapiens ... 30 4.6
AF324230-1|AAK11598.1| 337|Homo sapiens apolipoprotein L-II pro... 30 4.6
AF324224-1|AAK11593.1| 337|Homo sapiens apolipoprotein L-II pro... 30 4.6
AF324223-1|AAK11592.1| 337|Homo sapiens apolipoprotein L-II pro... 30 4.6
AF305429-1|AAL09359.1| 337|Homo sapiens apolipoprotein L2 protein. 30 4.6
AF305225-1|AAK20211.1| 337|Homo sapiens apolipoprotein L2 protein. 30 4.6
AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital... 30 4.6
AB208990-1|BAD92227.1| 415|Homo sapiens apolipoprotein L2 varia... 30 4.6
CR381696-1|CAI95409.1| 245|Homo sapiens dehydrogenase/reductase... 30 6.1
BX649443-1|CAI95430.1| 245|Homo sapiens dehydrogenase/reductase... 30 6.1
BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase... 30 6.1
AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase... 30 6.1
AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase... 30 6.1
AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase... 30 6.1
AF179237-1|AAD55402.1| 302|Homo sapiens short-chain dehydrogena... 30 6.1
AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain deh... 30 6.1
M76231-1|AAA60314.1| 261|Homo sapiens sepiapterin reductase pro... 29 8.0
BC017310-1|AAH17310.1| 261|Homo sapiens sepiapterin reductase (... 29 8.0
AK222942-1|BAD96662.1| 261|Homo sapiens sepiapterin reductase (... 29 8.0
AC092630-1|AAY15035.1| 198|Homo sapiens unknown protein. 29 8.0
AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase... 29 8.0
AB017547-1|BAA34534.1| 198|Homo sapiens sepiapterin reductase p... 29 8.0
>BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 87.4 bits (207), Expect = 3e-17
Identities = 58/170 (34%), Positives = 89/170 (52%), Gaps = 4/170 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAG-MHKGIETEAAKALEKLCA---HTFPLDVTRVESVQ 212
GCDSG G+A+A L +GF+ AG + K + K L+ L + T L+V E V+
Sbjct: 62 GCDSGFGFALAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVE 121
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
+ + V + LKD P+ +VNNAG+ T G+ E+ + + VNL G +R+ +FL
Sbjct: 122 KVVEIVRSSLKD-PEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFL 180
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
P IR+ K R++N+ S G PA + Y +K G+ A + CL
Sbjct: 181 PLIRRA--------KGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCL 222
>BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 86.2 bits (204), Expect = 7e-17
Identities = 57/170 (33%), Positives = 89/170 (52%), Gaps = 4/170 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAG-MHKGIETEAAKALEKLCA---HTFPLDVTRVESVQ 212
GCDSG G+++A L +GF+ AG + K + K L+ L + T L+V E V+
Sbjct: 62 GCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVE 121
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
+ + V + LKD P+ +VNNAG+ T G+ E+ + + VNL G +R+ +FL
Sbjct: 122 KVVEIVRSSLKD-PEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFL 180
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
P IR+ K R++N+ S G PA + Y +K G+ A + CL
Sbjct: 181 PLIRRA--------KGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCL 222
>BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 86.2 bits (204), Expect = 7e-17
Identities = 57/170 (33%), Positives = 89/170 (52%), Gaps = 4/170 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAG-MHKGIETEAAKALEKLCA---HTFPLDVTRVESVQ 212
GCDSG G+++A L +GF+ AG + K + K L+ L + T L+V E V+
Sbjct: 62 GCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVE 121
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
+ + V + LKD P+ +VNNAG+ T G+ E+ + + VNL G +R+ +FL
Sbjct: 122 KVVEIVRSSLKD-PEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFL 180
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
P IR+ K R++N+ S G PA + Y +K G+ A + CL
Sbjct: 181 PLIRRA--------KGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCL 222
>M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate
dehydrogenase protein.
Length = 343
Score = 77.8 bits (183), Expect = 2e-14
Identities = 54/170 (31%), Positives = 85/170 (50%), Gaps = 4/170 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAG-MHKGIETEAAKALEKLCA---HTFPLDVTRVESVQ 212
GCDSG G+++A L +GF+ AG + K + K L+ L + T L+V R E V+
Sbjct: 62 GCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVFRSEEVE 121
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
+ + P+ +VNNAG+ T G+ E+ + + VNL G +R+ +FL
Sbjct: 122 KVVGDC-PFEPEGPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFL 180
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
P IR+ K R++N+ S G PA + Y +K G+ A + CL
Sbjct: 181 PLIRRA--------KGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCL 222
>U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogenase
protein.
Length = 318
Score = 63.7 bits (148), Expect = 4e-10
Identities = 51/167 (30%), Positives = 79/167 (47%), Gaps = 1/167 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRK 224
GCDSG G +A +L + GF +A E + + HT LD+T +SVQ+ K
Sbjct: 35 GCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAK 94
Query: 225 YVLTVLKDNPKYKFHAVVNNAGVM-TVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+V +K+ + +VNNAGV +G W+T + ++VN +G + V A LP +
Sbjct: 95 WVEMHVKEAGLF---GLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLL 151
Query: 402 RKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
++ + R+IN+ S G Y SK GL A + L
Sbjct: 152 QQA--------RGRVINITSVLGRLAANG-GGYCVSKFGLEAFSDSL 189
>BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5
(11-cis/9-cis) protein.
Length = 318
Score = 63.7 bits (148), Expect = 4e-10
Identities = 51/167 (30%), Positives = 79/167 (47%), Gaps = 1/167 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRK 224
GCDSG G +A +L + GF +A E + + HT LD+T +SVQ+ K
Sbjct: 35 GCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAK 94
Query: 225 YVLTVLKDNPKYKFHAVVNNAGVM-TVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+V +K+ + +VNNAGV +G W+T + ++VN +G + V A LP +
Sbjct: 95 WVEMHVKEAGLF---GLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLL 151
Query: 402 RKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
++ + R+IN+ S G Y SK GL A + L
Sbjct: 152 QQA--------RGRVINITSVLGRLAANG-GGYCVSKFGLEAFSDSL 189
>AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase
protein.
Length = 318
Score = 63.7 bits (148), Expect = 4e-10
Identities = 51/167 (30%), Positives = 79/167 (47%), Gaps = 1/167 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRK 224
GCDSG G +A +L + GF +A E + + HT LD+T +SVQ+ K
Sbjct: 35 GCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAK 94
Query: 225 YVLTVLKDNPKYKFHAVVNNAGVM-TVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+V +K+ + +VNNAGV +G W+T + ++VN +G + V A LP +
Sbjct: 95 WVEMHVKEAGLF---GLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLL 151
Query: 402 RKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
++ + R+IN+ S G Y SK GL A + L
Sbjct: 152 QQA--------RGRVINITSVLGRLAANG-GGYCVSKFGLEAFSDSL 189
>BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 6 homolog (mouse) protein.
Length = 317
Score = 61.3 bits (142), Expect = 2e-09
Identities = 51/169 (30%), Positives = 81/169 (47%), Gaps = 3/169 (1%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGM--HKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
GCDSG G +A +L G +A KG E + ++L T LDVT++ES+
Sbjct: 36 GCDSGFGNLLARQLDARGLRVLAACLTEKGAEQLRGQTSDRL--ETVTLDVTKMESIAAA 93
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGVMT-VGKYEWMTASMIESPVHVNLLGAMRVISAFLP 395
++V + D + +VNNAG++T + EW+ + + VNL+G ++V + LP
Sbjct: 94 TQWVKEHVGDRGLW---GLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQVTLSMLP 150
Query: 396 EIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+R+ + RI+NV S G Y SK G+ A + L
Sbjct: 151 LVRRA--------RGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDIL 190
>AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimerase
protein.
Length = 317
Score = 61.3 bits (142), Expect = 2e-09
Identities = 51/169 (30%), Positives = 81/169 (47%), Gaps = 3/169 (1%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGM--HKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
GCDSG G +A +L G +A KG E + ++L T LDVT++ES+
Sbjct: 36 GCDSGFGNLLARQLDARGLRVLAACLTEKGAEQLRGQTSDRL--ETVTLDVTKMESIAAA 93
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGVMT-VGKYEWMTASMIESPVHVNLLGAMRVISAFLP 395
++V + D + +VNNAG++T + EW+ + + VNL+G ++V + LP
Sbjct: 94 TQWVKEHVGDRGLW---GLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQVTLSMLP 150
Query: 396 EIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+R+ + RI+NV S G Y SK G+ A + L
Sbjct: 151 LVRRA--------RGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDIL 190
>AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein.
Length = 317
Score = 61.3 bits (142), Expect = 2e-09
Identities = 51/169 (30%), Positives = 81/169 (47%), Gaps = 3/169 (1%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGM--HKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
GCDSG G +A +L G +A KG E + ++L T LDVT++ES+
Sbjct: 36 GCDSGFGNLLARQLDARGLRVLAACLTEKGAEQLRGQTSDRL--ETVTLDVTKMESIAAA 93
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGVMT-VGKYEWMTASMIESPVHVNLLGAMRVISAFLP 395
++V + D + +VNNAG++T + EW+ + + VNL+G ++V + LP
Sbjct: 94 TQWVKEHVGDRGLW---GLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQVTLSMLP 150
Query: 396 EIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+R+ + RI+NV S G Y SK G+ A + L
Sbjct: 151 LVRRA--------RGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDIL 190
>AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol
dehydrogenase protein.
Length = 317
Score = 59.7 bits (138), Expect = 7e-09
Identities = 53/169 (31%), Positives = 79/169 (46%), Gaps = 3/169 (1%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAG--MHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
GCDSG G +A +L G +A KG E + ++L T LDVT+ ESV
Sbjct: 36 GCDSGFGKLLARQLDARGLRVLAACLTEKGAEQLRGQTSDRL--ETVTLDVTKTESVAAA 93
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGV-MTVGKYEWMTASMIESPVHVNLLGAMRVISAFLP 395
++V ++D + +VNNAG+ + E +T + + VNLLG + V + LP
Sbjct: 94 AQWVKECVRDKGLW---GLVNNAGISLPTAPNELLTKQDFVTILDVNLLGVIDVTLSLLP 150
Query: 396 EIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+RK + R++NV S G L Y SK G+ A + L
Sbjct: 151 LVRKA--------RGRVVNVSSVMGRVSLFG-GGYCISKYGVEAFSDSL 190
>L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid
dehydrogenase protein.
Length = 387
Score = 59.3 bits (137), Expect = 9e-09
Identities = 51/165 (30%), Positives = 79/165 (47%), Gaps = 6/165 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---HTFPLDVTRVESVQE 215
G D GLG A+ L GF AG+ A+ L + C+ +D+T+ +++
Sbjct: 89 GGDCGLGHALCKYLDELGFTVFAGVLNE-NGPGAEELRRTCSPRLSVLQMDITKPVQIKD 147
Query: 216 FRKYVLTVLKDNPKYKFHAVVNNAGVM---TVGKYEWMTASMIESPVHVNLLGAMRVISA 386
V +L+D + AV+NNAGV+ T G+ MT + + VN G + V
Sbjct: 148 AYSKVAAMLQDRGLW---AVINNAGVLGFPTDGELLLMTD--YKQCMAVNFFGTVEVTKT 202
Query: 387 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGL 521
FLP +RK+ K R++NV S G P+ A+Y +SKA +
Sbjct: 203 FLPLLRKS--------KGRLVNVSSMGGGAPMERLASYGSSKAAV 239
>L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid
dehydrogenase type 2 protein.
Length = 387
Score = 59.3 bits (137), Expect = 9e-09
Identities = 51/165 (30%), Positives = 79/165 (47%), Gaps = 6/165 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---HTFPLDVTRVESVQE 215
G D GLG A+ L GF AG+ A+ L + C+ +D+T+ +++
Sbjct: 89 GGDCGLGHALCKYLDELGFTVFAGVLNE-NGPGAEELRRTCSPRLSVLQMDITKPVQIKD 147
Query: 216 FRKYVLTVLKDNPKYKFHAVVNNAGVM---TVGKYEWMTASMIESPVHVNLLGAMRVISA 386
V +L+D + AV+NNAGV+ T G+ MT + + VN G + V
Sbjct: 148 AYSKVAAMLQDRGLW---AVINNAGVLGFPTDGELLLMTD--YKQCMAVNFFGTVEVTKT 202
Query: 387 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGL 521
FLP +RK+ K R++NV S G P+ A+Y +SKA +
Sbjct: 203 FLPLLRKS--------KGRLVNVSSMGGGAPMERLASYGSSKAAV 239
>BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 59.3 bits (137), Expect = 9e-09
Identities = 51/165 (30%), Positives = 79/165 (47%), Gaps = 6/165 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---HTFPLDVTRVESVQE 215
G D GLG A+ L GF AG+ A+ L + C+ +D+T+ +++
Sbjct: 89 GGDCGLGHALCKYLDELGFTVFAGVLNE-NGPGAEELRRTCSPRLSVLQMDITKPVQIKD 147
Query: 216 FRKYVLTVLKDNPKYKFHAVVNNAGVM---TVGKYEWMTASMIESPVHVNLLGAMRVISA 386
V +L+D + AV+NNAGV+ T G+ MT + + VN G + V
Sbjct: 148 AYSKVAAMLQDRGLW---AVINNAGVLGFPTDGELLLMTD--YKQCMAVNFFGTVEVTKT 202
Query: 387 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGL 521
FLP +RK+ K R++NV S G P+ A+Y +SKA +
Sbjct: 203 FLPLLRKS--------KGRLVNVSSMGGGAPMERLASYGSSKAAV 239
>BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 59.3 bits (137), Expect = 9e-09
Identities = 51/165 (30%), Positives = 79/165 (47%), Gaps = 6/165 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---HTFPLDVTRVESVQE 215
G D GLG A+ L GF AG+ A+ L + C+ +D+T+ +++
Sbjct: 89 GGDCGLGHALCKYLDELGFTVFAGVLNE-NGPGAEELRRTCSPRLSVLQMDITKPVQIKD 147
Query: 216 FRKYVLTVLKDNPKYKFHAVVNNAGVM---TVGKYEWMTASMIESPVHVNLLGAMRVISA 386
V +L+D + AV+NNAGV+ T G+ MT + + VN G + V
Sbjct: 148 AYSKVAAMLQDRGLW---AVINNAGVLGFPTDGELLLMTD--YKQCMAVNFFGTVEVTKT 202
Query: 387 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGL 521
FLP +RK+ K R++NV S G P+ A+Y +SKA +
Sbjct: 203 FLPLLRKS--------KGRLVNVSSMGGGAPMERLASYGSSKAAV 239
>AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 59.3 bits (137), Expect = 9e-09
Identities = 51/165 (30%), Positives = 79/165 (47%), Gaps = 6/165 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---HTFPLDVTRVESVQE 215
G D GLG A+ L GF AG+ A+ L + C+ +D+T+ +++
Sbjct: 89 GGDCGLGHALCKYLDELGFTVFAGVLNE-NGPGAEELRRTCSPRLSVLQMDITKPVQIKD 147
Query: 216 FRKYVLTVLKDNPKYKFHAVVNNAGVM---TVGKYEWMTASMIESPVHVNLLGAMRVISA 386
V +L+D + AV+NNAGV+ T G+ MT + + VN G + V
Sbjct: 148 AYSKVAAMLQDRGLW---AVINNAGVLGFPTDGELLLMTD--YKQCMAVNFFGTVEVTKT 202
Query: 387 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGL 521
FLP +RK+ K R++NV S G P+ A+Y +SKA +
Sbjct: 203 FLPLLRKS--------KGRLVNVSSMGGGAPMERLASYGSSKAAV 239
>AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 variant protein.
Length = 387
Score = 59.3 bits (137), Expect = 9e-09
Identities = 51/165 (30%), Positives = 79/165 (47%), Gaps = 6/165 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---HTFPLDVTRVESVQE 215
G D GLG A+ L GF AG+ A+ L + C+ +D+T+ +++
Sbjct: 89 GGDCGLGHALCKYLDELGFTVFAGVLNE-NGPGAEELRRTCSPRLSVLQMDITKPVQIKD 147
Query: 216 FRKYVLTVLKDNPKYKFHAVVNNAGVM---TVGKYEWMTASMIESPVHVNLLGAMRVISA 386
V +L+D + AV+NNAGV+ T G+ MT + + VN G + V
Sbjct: 148 AYSKVAAMLQDRGLW---AVINNAGVLGFPTDGELLLMTD--YKQCMAVNFFGTVEVTKT 202
Query: 387 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGL 521
FLP +RK+ K R++NV S G P+ A+Y +SKA +
Sbjct: 203 FLPLLRKS--------KGRLVNVSSMGGGAPMERLASYGSSKAAV 239
>U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha
hydroxysteroid dehydrogenase protein.
Length = 317
Score = 58.8 bits (136), Expect = 1e-08
Identities = 39/124 (31%), Positives = 65/124 (52%), Gaps = 3/124 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGM--HKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
GCDSG G +A +L G +A KG E + ++L T LDVT++ES+
Sbjct: 36 GCDSGFGNLLARQLDARGLRVLAACLTDKGAEQLRGQTSDRL--ETVTLDVTKMESIAAA 93
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGVMT-VGKYEWMTASMIESPVHVNLLGAMRVISAFLP 395
++V + D + +VNNAG++T + EW+ + + VNL+G ++V + LP
Sbjct: 94 TQWVKEHVGDR---RLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQVTLSMLP 150
Query: 396 EIRK 407
+R+
Sbjct: 151 LVRR 154
>U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific
dehydrogenase protein.
Length = 318
Score = 56.8 bits (131), Expect = 5e-08
Identities = 48/167 (28%), Positives = 78/167 (46%), Gaps = 1/167 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRK 224
GCDSG G +A +L ++ F +A E + + +T LD+T +S Q+ K
Sbjct: 35 GCDSGFGRLLALQLDQKSFRVLASCLTPSGAEDLQGVASSGFNTTLLDITDPQSFQQAAK 94
Query: 225 YVLTVLKDNPKYKFHAVVNNAGVM-TVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+V +K+ + +VNNAGV +G W+T + ++VN +G + V A LP +
Sbjct: 95 WVEMHVKEAGLF---GLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLL 151
Query: 402 RKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
++ + R+IN+ S G Y SK GL A + L
Sbjct: 152 QQA--------RGRVINITSVLGRLAANG-GGYCVSKFGLEAFSDSL 189
>BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase
(SDR family) member 9 protein.
Length = 319
Score = 56.4 bits (130), Expect = 6e-08
Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRK 224
GCDSG G A ++GF IA + A KA T LDVT E+V+ +
Sbjct: 36 GCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSERLRTVLLDVTDPENVKRTAQ 95
Query: 225 YVLTVLKDNPKYKFHAVVNNAGVMTV-GKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+V + + + ++NNAGV V +W+T P+ VNL G + V LP +
Sbjct: 96 WVKNQVGEKGLW---GLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLV 152
Query: 402 RK 407
+K
Sbjct: 153 KK 154
>AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein.
Length = 319
Score = 56.4 bits (130), Expect = 6e-08
Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRK 224
GCDSG G A ++GF IA + A KA T LDVT E+V+ +
Sbjct: 36 GCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSERLRTVLLDVTDPENVKRTAQ 95
Query: 225 YVLTVLKDNPKYKFHAVVNNAGVMTV-GKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+V + + + ++NNAGV V +W+T P+ VNL G + V LP +
Sbjct: 96 WVKNQVGEKGLW---GLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLV 152
Query: 402 RK 407
+K
Sbjct: 153 KK 154
>AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase
protein.
Length = 319
Score = 56.4 bits (130), Expect = 6e-08
Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRK 224
GCDSG G A ++GF IA + A KA T LDVT E+V+ +
Sbjct: 36 GCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSERLRTVLLDVTDPENVKRTAQ 95
Query: 225 YVLTVLKDNPKYKFHAVVNNAGVMTV-GKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+V + + + ++NNAGV V +W+T P+ VNL G + V LP +
Sbjct: 96 WVKNQVGEKGLW---GLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLV 152
Query: 402 RK 407
+K
Sbjct: 153 KK 154
>AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript A protein.
Length = 319
Score = 56.4 bits (130), Expect = 6e-08
Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRK 224
GCDSG G A ++GF IA + A KA T LDVT E+V+ +
Sbjct: 36 GCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSERLRTVLLDVTDPENVKRTAQ 95
Query: 225 YVLTVLKDNPKYKFHAVVNNAGVMTV-GKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+V + + + ++NNAGV V +W+T P+ VNL G + V LP +
Sbjct: 96 WVKNQVGEKGLW---GLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLV 152
Query: 402 RK 407
+K
Sbjct: 153 KK 154
>AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript B protein.
Length = 319
Score = 56.4 bits (130), Expect = 6e-08
Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRK 224
GCDSG G A ++GF IA + A KA T LDVT E+V+ +
Sbjct: 36 GCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSERLRTVLLDVTDPENVKRTAQ 95
Query: 225 YVLTVLKDNPKYKFHAVVNNAGVMTV-GKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+V + + + ++NNAGV V +W+T P+ VNL G + V LP +
Sbjct: 96 WVKNQVGEKGLW---GLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLV 152
Query: 402 RK 407
+K
Sbjct: 153 KK 154
>AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript C protein.
Length = 319
Score = 56.4 bits (130), Expect = 6e-08
Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRK 224
GCDSG G A ++GF IA + A KA T LDVT E+V+ +
Sbjct: 36 GCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSERLRTVLLDVTDPENVKRTAQ 95
Query: 225 YVLTVLKDNPKYKFHAVVNNAGVMTV-GKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+V + + + ++NNAGV V +W+T P+ VNL G + V LP +
Sbjct: 96 WVKNQVGEKGLW---GLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLV 152
Query: 402 RK 407
+K
Sbjct: 153 KK 154
>AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase protein.
Length = 319
Score = 56.4 bits (130), Expect = 6e-08
Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRK 224
GCDSG G A ++GF IA + A KA T LDVT E+V+ +
Sbjct: 36 GCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSERLRTVLLDVTDPENVKRTAQ 95
Query: 225 YVLTVLKDNPKYKFHAVVNNAGVMTV-GKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+V + + + ++NNAGV V +W+T P+ VNL G + V LP +
Sbjct: 96 WVKNQVGEKGLW---GLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLV 152
Query: 402 RK 407
+K
Sbjct: 153 KK 154
>AF295380-1|AAL37037.1| 319|Homo sapiens short-chain
dehydrogenase/reductase RETSDR8 protein.
Length = 319
Score = 56.4 bits (130), Expect = 6e-08
Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRK 224
GCDSG G A ++GF IA + A KA T LDVT E+V+ +
Sbjct: 36 GCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSERLRTVLLDVTDPENVKRTAQ 95
Query: 225 YVLTVLKDNPKYKFHAVVNNAGVMTV-GKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+V + + + ++NNAGV V +W+T P+ VNL G + V LP +
Sbjct: 96 WVKNQVGEKGLW---GLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLV 152
Query: 402 RK 407
+K
Sbjct: 153 KK 154
>AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase
homolog isoform-1 protein.
Length = 279
Score = 56.4 bits (130), Expect = 6e-08
Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRK 224
GCDSG G A ++GF IA + A KA T LDVT E+V+ +
Sbjct: 36 GCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSERLRTVLLDVTDPENVKRTAQ 95
Query: 225 YVLTVLKDNPKYKFHAVVNNAGVMTV-GKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+V + + + ++NNAGV V +W+T P+ VNL G + V LP +
Sbjct: 96 WVKNQVGEKGLW---GLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLV 152
Query: 402 RK 407
+K
Sbjct: 153 KK 154
>AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase
protein.
Length = 317
Score = 56.4 bits (130), Expect = 6e-08
Identities = 52/169 (30%), Positives = 79/169 (46%), Gaps = 3/169 (1%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAG--MHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
GCDSG G +A +L G +A KG E + ++L T LDVT+ ESV
Sbjct: 36 GCDSGFGKLLARQLDARGLRVLAACLTEKGAEQLRGQTSDRL--ETVTLDVTKTESVAAA 93
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGV-MTVGKYEWMTASMIESPVHVNLLGAMRVISAFLP 395
++V ++D + +VNNAG+ + E +T + + + VNLLG + V LP
Sbjct: 94 AQWVKECVRDKGLW---GLVNNAGISLPTAPNELLTKQDLLTILDVNLLGVIDVTLNLLP 150
Query: 396 EIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+R+ + R++NV S G L Y SK G+ A + L
Sbjct: 151 LVRRA--------RGRVVNVFSVMGRVSLFG-GGYCISKYGVEAFSDSL 190
>AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein.
Length = 245
Score = 56.4 bits (130), Expect = 6e-08
Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 1/122 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRK 224
GCDSG G A ++GF IA + A KA T LDVT E+V+ +
Sbjct: 36 GCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSERLRTVLLDVTDPENVKRTAQ 95
Query: 225 YVLTVLKDNPKYKFHAVVNNAGVMTV-GKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+V + + + ++NNAGV V +W+T P+ VNL G + V LP +
Sbjct: 96 WVKNQVGEKGLW---GLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLV 152
Query: 402 RK 407
+K
Sbjct: 153 KK 154
>U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase 2 protein.
Length = 405
Score = 55.6 bits (128), Expect = 1e-07
Identities = 45/163 (27%), Positives = 69/163 (42%), Gaps = 4/163 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---HTFPLDVTRVESVQE 215
GCDSG G A +L GF +A + + + + A L C+ +D+T+ +
Sbjct: 89 GCDSGFGKETAKKLDSMGFTVLATVLE-LNSPGAIELRTCCSPRLRLLQMDLTKPGDISR 147
Query: 216 FRKYVLTVLKDNPKYKFHAVVNNAGVM-TVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
F ++ + +VNNAG V E + S + VN GA+ + L
Sbjct: 148 FLEFTKAHTTSTGLW---GLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLL 204
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGL 521
P +R + + RI+ VGS G P P AY SKA +
Sbjct: 205 PLLRSS--------RGRIVTVGSPAGDMPYPCLGAYGTSKAAV 239
>BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 55.2 bits (127), Expect = 1e-07
Identities = 45/164 (27%), Positives = 76/164 (46%), Gaps = 1/164 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRK 224
GCDSG G +A +L G +A ++ + T LDVT+ ES++ +
Sbjct: 32 GCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQRDTSYRLQTTLLDVTKSESIKAAAQ 91
Query: 225 YVLTVLKDNPKYKFHAVVNNAGV-MTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+V + + + A+VNNAGV + G EW+T ++VNL+G + V LP +
Sbjct: 92 WVRDKVGEQGLW---ALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIEVTLHMLPMV 148
Query: 402 RKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALT 533
++ + R++N+ S G + Y SK G+ A +
Sbjct: 149 KRA--------RGRVVNMSSSGGRVAVIG-GGYCVSKFGVEAFS 183
>BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 55.2 bits (127), Expect = 1e-07
Identities = 45/164 (27%), Positives = 76/164 (46%), Gaps = 1/164 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRK 224
GCDSG G +A +L G +A ++ + T LDVT+ ES++ +
Sbjct: 32 GCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQRDTSYRLQTTLLDVTKSESIKAAAQ 91
Query: 225 YVLTVLKDNPKYKFHAVVNNAGV-MTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+V + + + A+VNNAGV + G EW+T ++VNL+G + V LP +
Sbjct: 92 WVRDKVGEQGLW---ALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIEVTLHMLPMV 148
Query: 402 RKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALT 533
++ + R++N+ S G + Y SK G+ A +
Sbjct: 149 KRA--------RGRVVNMSSSGGRVAVIG-GGYCVSKFGVEAFS 183
>AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase
similar protein protein.
Length = 313
Score = 55.2 bits (127), Expect = 1e-07
Identities = 45/164 (27%), Positives = 76/164 (46%), Gaps = 1/164 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRK 224
GCDSG G +A +L G +A ++ + T LDVT+ ES++ +
Sbjct: 32 GCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQRDTSYRLQTTLLDVTKSESIKAAAQ 91
Query: 225 YVLTVLKDNPKYKFHAVVNNAGV-MTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+V + + + A+VNNAGV + G EW+T ++VNL+G + V LP +
Sbjct: 92 WVRDKVGEQGLW---ALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIEVTLHMLPMV 148
Query: 402 RKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALT 533
++ + R++N+ S G + Y SK G+ A +
Sbjct: 149 KRA--------RGRVVNMSSSGGRVAVIG-GGYCVSKFGVEAFS 183
>X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for
17-beta-hydroxysteroid dehydrogenase (17-HSD) (EC
1.1.1.62). ).
Length = 328
Score = 54.0 bits (124), Expect = 3e-07
Identities = 54/175 (30%), Positives = 82/175 (46%), Gaps = 9/175 (5%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG------FITIAGMH-KGIETEAAKALE--KLCAHTFPLDVTR 197
GC SG+G +A RLA + + T+ + +G EAA+AL T LDV
Sbjct: 10 GCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRD 69
Query: 198 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 377
+SV R+ V D +V NAG+ +G E + + S + VN++G +R+
Sbjct: 70 SKSVAAARERVTEGRVD-------VLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 378 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ AFLP++++ + R++ GS GL LP Y ASK L L L
Sbjct: 123 LQAFLPDMKR-------RGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
>U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 54.0 bits (124), Expect = 3e-07
Identities = 54/175 (30%), Positives = 82/175 (46%), Gaps = 9/175 (5%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG------FITIAGMH-KGIETEAAKALE--KLCAHTFPLDVTR 197
GC SG+G +A RLA + + T+ + +G EAA+AL T LDV
Sbjct: 10 GCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRD 69
Query: 198 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 377
+SV R+ V D +V NAG+ +G E + + S + VN++G +R+
Sbjct: 70 SKSVAAARERVTEGRVD-------VLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 378 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ AFLP++++ + R++ GS GL LP Y ASK L L L
Sbjct: 123 LQAFLPDMKR-------RGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
>M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 54.0 bits (124), Expect = 3e-07
Identities = 54/175 (30%), Positives = 82/175 (46%), Gaps = 9/175 (5%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG------FITIAGMH-KGIETEAAKALE--KLCAHTFPLDVTR 197
GC SG+G +A RLA + + T+ + +G EAA+AL T LDV
Sbjct: 10 GCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRD 69
Query: 198 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 377
+SV R+ V D +V NAG+ +G E + + S + VN++G +R+
Sbjct: 70 SKSVAAARERVTEGRVD-------VLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 378 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ AFLP++++ + R++ GS GL LP Y ASK L L L
Sbjct: 123 LQAFLPDMKR-------RGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
>M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental
17-beta-hydroxysteroid dehydrogenase mRNA, complete cds.
).
Length = 328
Score = 54.0 bits (124), Expect = 3e-07
Identities = 54/175 (30%), Positives = 82/175 (46%), Gaps = 9/175 (5%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG------FITIAGMH-KGIETEAAKALE--KLCAHTFPLDVTR 197
GC SG+G +A RLA + + T+ + +G EAA+AL T LDV
Sbjct: 10 GCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRD 69
Query: 198 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 377
+SV R+ V D +V NAG+ +G E + + S + VN++G +R+
Sbjct: 70 SKSVAAARERVTEGRVD-------VLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 378 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ AFLP++++ + R++ GS GL LP Y ASK L L L
Sbjct: 123 LQAFLPDMKR-------RGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
>M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol 17
beta-dehydrogenase gene, complete cds. ).
Length = 328
Score = 54.0 bits (124), Expect = 3e-07
Identities = 54/175 (30%), Positives = 82/175 (46%), Gaps = 9/175 (5%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG------FITIAGMH-KGIETEAAKALE--KLCAHTFPLDVTR 197
GC SG+G +A RLA + + T+ + +G EAA+AL T LDV
Sbjct: 10 GCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRD 69
Query: 198 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 377
+SV R+ V D +V NAG+ +G E + + S + VN++G +R+
Sbjct: 70 SKSVAAARERVTEGRVD-------VLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 378 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ AFLP++++ + R++ GS GL LP Y ASK L L L
Sbjct: 123 LQAFLPDMKR-------RGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
>BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 54.0 bits (124), Expect = 3e-07
Identities = 54/175 (30%), Positives = 82/175 (46%), Gaps = 9/175 (5%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG------FITIAGMH-KGIETEAAKALE--KLCAHTFPLDVTR 197
GC SG+G +A RLA + + T+ + +G EAA+AL T LDV
Sbjct: 10 GCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRD 69
Query: 198 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 377
+SV R+ V D +V NAG+ +G E + + S + VN++G +R+
Sbjct: 70 SKSVAAARERVTEGRVD-------VLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 378 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ AFLP++++ + R++ GS GL LP Y ASK L L L
Sbjct: 123 LQAFLPDMKR-------RGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
>BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 54.0 bits (124), Expect = 3e-07
Identities = 54/175 (30%), Positives = 82/175 (46%), Gaps = 9/175 (5%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG------FITIAGMH-KGIETEAAKALE--KLCAHTFPLDVTR 197
GC SG+G +A RLA + + T+ + +G EAA+AL T LDV
Sbjct: 10 GCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRD 69
Query: 198 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 377
+SV R+ V D +V NAG+ +G E + + S + VN++G +R+
Sbjct: 70 SKSVAAARERVTEGRVD-------VLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 378 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ AFLP++++ + R++ GS GL LP Y ASK L L L
Sbjct: 123 LQAFLPDMKR-------RGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 170
>U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase type II protein.
Length = 405
Score = 53.2 bits (122), Expect = 6e-07
Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 4/163 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---HTFPLDVTRVESVQE 215
GCDSG G A +L GF +A + + + + A L C+ +D+T+ +
Sbjct: 89 GCDSGFGKETAKKLDSMGFTVLATVLE-LNSPGAIELRTCCSPRLRLLQMDLTKPGDISR 147
Query: 216 FRKYVLTVLKDNPKYKFHAVVNNAGVM-TVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
++ + +VNNAG V E + S + VN GA+ + L
Sbjct: 148 LLEFTKAHTTSTGLW---GLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLL 204
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGL 521
P +R + + RI+ VGS G P P AY SKA +
Sbjct: 205 PLLRSS--------RGRIVTVGSPAGDMPYPCLGAYGTSKAAV 239
>U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase type 2 protein.
Length = 405
Score = 52.8 bits (121), Expect = 8e-07
Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 4/163 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---HTFPLDVTRVESVQE 215
GCDSG G A +L GF +A + + + + A L C+ +D+T+ +
Sbjct: 89 GCDSGFGKETAKKLDSMGFTVLATVLE-LNSPGAIELRTCCSPRLRLLQMDLTKPGDISR 147
Query: 216 FRKYVLTVLKDNPKYKFHAVVNNAGVM-TVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
++ + +VNNAG V E + S + VN GA+ + L
Sbjct: 148 VLEFTKAHTTSTGLW---GLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLL 204
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGL 521
P +R + + RI+ VGS G P P AY SKA +
Sbjct: 205 PLLRSS--------RGRIVTVGSPAGDMPYPCLGAYGTSKAAV 239
>EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 52.8 bits (121), Expect = 8e-07
Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 4/163 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---HTFPLDVTRVESVQE 215
GCDSG G A +L GF +A + + + + A L C+ +D+T+ +
Sbjct: 89 GCDSGFGKETAKKLDSMGFTVLATVLE-LNSPGAIELRTCCSPRLRLLQMDLTKPGDISR 147
Query: 216 FRKYVLTVLKDNPKYKFHAVVNNAGVM-TVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
++ + +VNNAG V E + S + VN GA+ + L
Sbjct: 148 VLEFTKAHTTSTGLW---GLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLL 204
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGL 521
P +R + + RI+ VGS G P P AY SKA +
Sbjct: 205 PLLRSS--------RGRIVTVGSPAGDMPYPCLGAYGTSKAAV 239
>BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 52.8 bits (121), Expect = 8e-07
Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 4/163 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---HTFPLDVTRVESVQE 215
GCDSG G A +L GF +A + + + + A L C+ +D+T+ +
Sbjct: 89 GCDSGFGKETAKKLDSMGFTVLATVLE-LNSPGAIELRTCCSPRLRLLQMDLTKPGDISR 147
Query: 216 FRKYVLTVLKDNPKYKFHAVVNNAGVM-TVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
++ + +VNNAG V E + S + VN GA+ + L
Sbjct: 148 VLEFTKAHTTSTGLW---GLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLL 204
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGL 521
P +R + + RI+ VGS G P P AY SKA +
Sbjct: 205 PLLRSS--------RGRIVTVGSPAGDMPYPCLGAYGTSKAAV 239
>BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 52.8 bits (121), Expect = 8e-07
Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 4/163 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---HTFPLDVTRVESVQE 215
GCDSG G A +L GF +A + + + + A L C+ +D+T+ +
Sbjct: 89 GCDSGFGKETAKKLDSMGFTVLATVLE-LNSPGAIELRTCCSPRLRLLQMDLTKPGDISR 147
Query: 216 FRKYVLTVLKDNPKYKFHAVVNNAGVM-TVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
++ + +VNNAG V E + S + VN GA+ + L
Sbjct: 148 VLEFTKAHTTSTGLW---GLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLL 204
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGL 521
P +R + + RI+ VGS G P P AY SKA +
Sbjct: 205 PLLRSS--------RGRIVTVGSPAGDMPYPCLGAYGTSKAAV 239
>BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 49.2 bits (112), Expect = 9e-06
Identities = 51/167 (30%), Positives = 77/167 (46%), Gaps = 1/167 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAH-TFPLDVTRVESVQEFR 221
G G+G AVA +AR+G+ +A + + +E A A + H F DV + VQ
Sbjct: 9 GGSRGIGRAVAQLMARKGY-RLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTF 67
Query: 222 KYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+ + L + + +VN AG+ G + S +H NLLG+M A +
Sbjct: 68 EELEKHLG-----RVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM--- 119
Query: 402 RKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+T I+ I+NVGS GL+ + YSASK GL +R L
Sbjct: 120 -RTMIQQQGGS---IVNVGSIVGLKGNSGQSVYSASKGGLVGFSRAL 162
>BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 49.2 bits (112), Expect = 9e-06
Identities = 51/167 (30%), Positives = 77/167 (46%), Gaps = 1/167 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAH-TFPLDVTRVESVQEFR 221
G G+G AVA +AR+G+ +A + + +E A A + H F DV + VQ
Sbjct: 9 GGSRGIGRAVAQLMARKGY-RLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTF 67
Query: 222 KYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+ + L + + +VN AG+ G + S +H NLLG+M A +
Sbjct: 68 EEMEKHLG-----RVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM--- 119
Query: 402 RKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+T I+ I+NVGS GL+ + YSASK GL +R L
Sbjct: 120 -RTMIQQQGGS---IVNVGSIVGLKGNSGQSVYSASKGGLVGFSRAL 162
>AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens
cDNA FLJ14431 fis, clone HEMBA1006521, weakly similar to
3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (EC
1.1.1.100). ).
Length = 179
Score = 49.2 bits (112), Expect = 9e-06
Identities = 51/167 (30%), Positives = 77/167 (46%), Gaps = 1/167 (0%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAH-TFPLDVTRVESVQEFR 221
G G+G AVA +AR+G+ +A + + +E A A + H F DV + VQ
Sbjct: 9 GGSRGIGRAVAQLMARKGY-RLAVIARNLEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTF 67
Query: 222 KYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEI 401
+ + L + + +VN AG+ G + S +H NLLG+M A +
Sbjct: 68 EEMEKHLG-----RVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAM--- 119
Query: 402 RKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+T I+ I+NVGS GL+ + YSASK GL +R L
Sbjct: 120 -RTMIQQQGGS---IVNVGSIVGLKGNSGQSVYSASKGGLVGFSRAL 162
>X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein.
Length = 332
Score = 46.8 bits (106), Expect = 5e-05
Identities = 44/169 (26%), Positives = 74/169 (43%), Gaps = 3/169 (1%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG-FITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFR 221
G SG+G +A ++G FIT+ ++ +A K +E + + + V +
Sbjct: 39 GGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDY 98
Query: 222 KYVLTVLKDNPKY--KFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLP 395
V V+K + +VN AG+ GK+E + S E + +N LG++ A +
Sbjct: 99 NQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVIT 158
Query: 396 EIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+++ + RI+ V S G L F AYSASK + L L
Sbjct: 159 TMKERRVG-------RIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEAL 200
>BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 46.8 bits (106), Expect = 5e-05
Identities = 44/169 (26%), Positives = 74/169 (43%), Gaps = 3/169 (1%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG-FITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFR 221
G SG+G +A ++G FIT+ ++ +A K +E + + + V +
Sbjct: 39 GGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDY 98
Query: 222 KYVLTVLKDNPKY--KFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLP 395
V V+K + +VN AG+ GK+E + S E + +N LG++ A +
Sbjct: 99 NQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVIT 158
Query: 396 EIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+++ + RI+ V S G L F AYSASK + L L
Sbjct: 159 TMKERRVG-------RIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEAL 200
>BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 46.8 bits (106), Expect = 5e-05
Identities = 44/169 (26%), Positives = 74/169 (43%), Gaps = 3/169 (1%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG-FITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFR 221
G SG+G +A ++G FIT+ ++ +A K +E + + + V +
Sbjct: 39 GGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDY 98
Query: 222 KYVLTVLKDNPKY--KFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLP 395
V V+K + +VN AG+ GK+E + S E + +N LG++ A +
Sbjct: 99 NQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVIT 158
Query: 396 EIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+++ + RI+ V S G L F AYSASK + L L
Sbjct: 159 TMKERRVG-------RIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEAL 200
>AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer
segment all-trans retinol dehydrogenase protein.
Length = 311
Score = 46.8 bits (106), Expect = 5e-05
Identities = 46/167 (27%), Positives = 82/167 (49%), Gaps = 8/167 (4%)
Frame = +3
Query: 45 GCDSGLGWAVAARLA---REGFITIA-----GMHKGIETEAAKALEKLCAHTFPLDVTRV 200
GC SG+G +A +LA ++ + +A G + +E A +AL + LDV
Sbjct: 12 GCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLT-VAQLDVCSD 70
Query: 201 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 380
ESV + L+ ++ + +VNNAG+ VG E ++ + +++ N GA+R++
Sbjct: 71 ESVAQ----CLSCIQG----EVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLV 122
Query: 381 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGL 521
A LP +++ + + I+ + S GLQ + Y+ASK L
Sbjct: 123 KAVLPGMKR-------RRQGHIVVISSVMGLQGVIFNDVYAASKFAL 162
>DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform protein.
Length = 278
Score = 42.3 bits (95), Expect = 0.001
Identities = 39/163 (23%), Positives = 70/163 (42%), Gaps = 1/163 (0%)
Frame = +3
Query: 57 GLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLT 236
G+G+A+A RLA++G + K + A A + + V V ++ + V T
Sbjct: 43 GIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVAT 102
Query: 237 VLKDNPKYKFHAVVNNAGVMT-VGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTA 413
+K + +V+NA V G +T + + + +N+ + A +PE+ K
Sbjct: 103 AVKLHG--GIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEK-- 158
Query: 414 IETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ ++ V S P P F+ Y+ SK L LT+ L
Sbjct: 159 -----RGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTL 196
>BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 protein.
Length = 278
Score = 42.3 bits (95), Expect = 0.001
Identities = 39/163 (23%), Positives = 70/163 (42%), Gaps = 1/163 (0%)
Frame = +3
Query: 57 GLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLT 236
G+G+A+A RLA++G + K + A A + + V V ++ + V T
Sbjct: 43 GIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVAT 102
Query: 237 VLKDNPKYKFHAVVNNAGVMT-VGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTA 413
+K + +V+NA V G +T + + + +N+ + A +PE+ K
Sbjct: 103 AVKLHG--GIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEK-- 158
Query: 414 IETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ ++ V S P P F+ Y+ SK L LT+ L
Sbjct: 159 -----RGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTL 196
>AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein.
Length = 278
Score = 42.3 bits (95), Expect = 0.001
Identities = 39/163 (23%), Positives = 70/163 (42%), Gaps = 1/163 (0%)
Frame = +3
Query: 57 GLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLT 236
G+G+A+A RLA++G + K + A A + + V V ++ + V T
Sbjct: 43 GIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVAT 102
Query: 237 VLKDNPKYKFHAVVNNAGVMT-VGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTA 413
+K + +V+NA V G +T + + + +N+ + A +PE+ K
Sbjct: 103 AVKLHG--GIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEK-- 158
Query: 414 IETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ ++ V S P P F+ Y+ SK L LT+ L
Sbjct: 159 -----RGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTL 196
>AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens
cDNA FLJ11008 fis, clone PLACE1003100, moderately
similar to HEP27 PROTEIN. ).
Length = 278
Score = 42.3 bits (95), Expect = 0.001
Identities = 39/163 (23%), Positives = 70/163 (42%), Gaps = 1/163 (0%)
Frame = +3
Query: 57 GLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLT 236
G+G+A+A RLA++G + K + A A + + V V ++ + V T
Sbjct: 43 GIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVAT 102
Query: 237 VLKDNPKYKFHAVVNNAGVMT-VGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTA 413
+K + +V+NA V G +T + + + +N+ + A +PE+ K
Sbjct: 103 AVKLHG--GIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEK-- 158
Query: 414 IETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ ++ V S P P F+ Y+ SK L LT+ L
Sbjct: 159 -----RGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTL 196
>AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol
dehydrogenase/reductase protein.
Length = 260
Score = 42.3 bits (95), Expect = 0.001
Identities = 39/163 (23%), Positives = 70/163 (42%), Gaps = 1/163 (0%)
Frame = +3
Query: 57 GLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLT 236
G+G+A+A RLA++G + K + A A + + V V ++ + V T
Sbjct: 25 GIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVAT 84
Query: 237 VLKDNPKYKFHAVVNNAGVMT-VGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTA 413
+K + +V+NA V G +T + + + +N+ + A +PE+ K
Sbjct: 85 AVKLHG--GIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEK-- 140
Query: 414 IETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ ++ V S P P F+ Y+ SK L LT+ L
Sbjct: 141 -----RGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTL 178
>AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein
protein.
Length = 278
Score = 41.9 bits (94), Expect = 0.001
Identities = 39/163 (23%), Positives = 70/163 (42%), Gaps = 1/163 (0%)
Frame = +3
Query: 57 GLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLT 236
G+G+A+A RLA++G + K + A A + + V V ++ + V T
Sbjct: 43 GIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCMVGKAEDRERLVAT 102
Query: 237 VLKDNPKYKFHAVVNNAGVMT-VGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTA 413
+K + +V+NA V G +T + + + +N+ + A +PE+ K
Sbjct: 103 AVKLHG--GIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEK-- 158
Query: 414 IETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ ++ V S P P F+ Y+ SK L LT+ L
Sbjct: 159 -----RGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTL 196
>AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 280
Score = 40.7 bits (91), Expect = 0.003
Identities = 45/169 (26%), Positives = 71/169 (42%), Gaps = 3/169 (1%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLD--VTRVESVQEF 218
G SG+G+A+A RLAR+G + K + +A+ KL + V V ++
Sbjct: 43 GSTSGIGFAIARRLARDGAHVVISSRK--QQNVDRAMAKLQGEGLSVAGIVCHVGKAEDR 100
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGV-MTVGKYEWMTASMIESPVHVNLLGAMRVISAFLP 395
+ V L+ F +V +AGV VG + + + + VN+ ++S LP
Sbjct: 101 EQLVAKALEHCGGVDF--LVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPAPLLSQLLP 158
Query: 396 EIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ + +I V S P+ A YS SK L LTR L
Sbjct: 159 YMENR--------RGAVILVSSVAAYNPVVALGVYSVSKTALLGLTRTL 199
>BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 40.3 bits (90), Expect = 0.004
Identities = 46/160 (28%), Positives = 66/160 (41%), Gaps = 4/160 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAR-EGFITIAGMHK-GIETEAAKALEKLCA--HTFPLDVTRVESVQ 212
G G+G A A+ + + + ++K G+E AAK + L A HTF +D + E +
Sbjct: 43 GAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC-KGLGAKVHTFVVDCSNREDIY 101
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
K V + D +VNNAGV+ IE VN+L AFL
Sbjct: 102 SSAKKVKAEIGD-----VSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFL 156
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 512
P + T I+ V S G +P AY +SK
Sbjct: 157 PAM-------TKNNHGHIVTVASAAGHVSVPFLLAYCSSK 189
>BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 40.3 bits (90), Expect = 0.004
Identities = 46/160 (28%), Positives = 66/160 (41%), Gaps = 4/160 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAR-EGFITIAGMHK-GIETEAAKALEKLCA--HTFPLDVTRVESVQ 212
G G+G A A+ + + + ++K G+E AAK + L A HTF +D + E +
Sbjct: 43 GAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC-KGLGAKVHTFVVDCSNREDIY 101
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
K V + D +VNNAGV+ IE VN+L AFL
Sbjct: 102 SSAKKVKAEIGD-----VSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFL 156
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 512
P + T I+ V S G +P AY +SK
Sbjct: 157 PAM-------TKNNHGHIVTVASAAGHVSVPFLLAYCSSK 189
>BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 40.3 bits (90), Expect = 0.004
Identities = 46/160 (28%), Positives = 66/160 (41%), Gaps = 4/160 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAR-EGFITIAGMHK-GIETEAAKALEKLCA--HTFPLDVTRVESVQ 212
G G+G A A+ + + + ++K G+E AAK + L A HTF +D + E +
Sbjct: 43 GAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC-KGLGAKVHTFVVDCSNREDIY 101
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
K V + D +VNNAGV+ IE VN+L AFL
Sbjct: 102 SSAKKVKAEIGD-----VSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFL 156
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 512
P + T I+ V S G +P AY +SK
Sbjct: 157 PAM-------TKNNHGHIVTVASAAGHVSVPFLLAYCSSK 189
>BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 40.3 bits (90), Expect = 0.004
Identities = 46/160 (28%), Positives = 66/160 (41%), Gaps = 4/160 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAR-EGFITIAGMHK-GIETEAAKALEKLCA--HTFPLDVTRVESVQ 212
G G+G A A+ + + + ++K G+E AAK + L A HTF +D + E +
Sbjct: 43 GAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC-KGLGAKVHTFVVDCSNREDIY 101
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
K V + D +VNNAGV+ IE VN+L AFL
Sbjct: 102 SSAKKVKAEIGD-----VSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFL 156
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 512
P + T I+ V S G +P AY +SK
Sbjct: 157 PAM-------TKNNHGHIVTVASAAGHVSVPFLLAYCSSK 189
>AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein.
Length = 300
Score = 40.3 bits (90), Expect = 0.004
Identities = 46/160 (28%), Positives = 66/160 (41%), Gaps = 4/160 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAR-EGFITIAGMHK-GIETEAAKALEKLCA--HTFPLDVTRVESVQ 212
G G+G A A+ + + + ++K G+E AAK + L A HTF +D + E +
Sbjct: 43 GAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC-KGLGAKVHTFVVDCSNREDIY 101
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
K V + D +VNNAGV+ IE VN+L AFL
Sbjct: 102 SSAKKVKAEIGD-----VSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFL 156
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 512
P + T I+ V S G +P AY +SK
Sbjct: 157 PAM-------TKNNHGHIVTVASAAGHVSVPFLLAYCSSK 189
>AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens
cDNA PSEC0029 fis, clone NT2RP1000544, highly similar to
Retinal short-chain dehydrogenase/reductase 2. ).
Length = 300
Score = 40.3 bits (90), Expect = 0.004
Identities = 46/160 (28%), Positives = 66/160 (41%), Gaps = 4/160 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAR-EGFITIAGMHK-GIETEAAKALEKLCA--HTFPLDVTRVESVQ 212
G G+G A A+ + + + ++K G+E AAK + L A HTF +D + E +
Sbjct: 43 GAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC-KGLGAKVHTFVVDCSNREDIY 101
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
K V + D +VNNAGV+ IE VN+L AFL
Sbjct: 102 SSAKKVKAEIGD-----VSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFL 156
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 512
P + T I+ V S G +P AY +SK
Sbjct: 157 PAM-------TKNNHGHIVTVASAAGHVSVPFLLAYCSSK 189
>AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen
HD-CL-03 protein.
Length = 300
Score = 40.3 bits (90), Expect = 0.004
Identities = 46/160 (28%), Positives = 66/160 (41%), Gaps = 4/160 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAR-EGFITIAGMHK-GIETEAAKALEKLCA--HTFPLDVTRVESVQ 212
G G+G A A+ + + + ++K G+E AAK + L A HTF +D + E +
Sbjct: 43 GAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC-KGLGAKVHTFVVDCSNREDIY 101
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
K V + D +VNNAGV+ IE VN+L AFL
Sbjct: 102 SSAKKVKAEIGD-----VSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFL 156
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 512
P + T I+ V S G +P AY +SK
Sbjct: 157 PAM-------TKNNHGHIVTVASAAGHVSVPFLLAYCSSK 189
>AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR2 protein.
Length = 300
Score = 40.3 bits (90), Expect = 0.004
Identities = 46/160 (28%), Positives = 66/160 (41%), Gaps = 4/160 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAR-EGFITIAGMHK-GIETEAAKALEKLCA--HTFPLDVTRVESVQ 212
G G+G A A+ + + + ++K G+E AAK + L A HTF +D + E +
Sbjct: 43 GAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC-KGLGAKVHTFVVDCSNREDIY 101
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
K V + D +VNNAGV+ IE VN+L AFL
Sbjct: 102 SSAKKVKAEIGD-----VSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFL 156
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 512
P + T I+ V S G +P AY +SK
Sbjct: 157 PAM-------TKNNHGHIVTVASAAGHVSVPFLLAYCSSK 189
>Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 39.9 bits (89), Expect = 0.006
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 9/172 (5%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
G SGLG A A RL +G + + + G E +A K L C P DVT + VQ
Sbjct: 17 GGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK-LGNNCVFA-PADVTSEKDVQT- 73
Query: 219 RKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKY------EWMTASMIESPVHVNLLGAMRV 377
L + K K+ + VN AG+ K + T + + VNL+G V
Sbjct: 74 ---ALALAKG--KFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128
Query: 378 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALT 533
I E+ + + + + IIN S + AAYSASK G+ +T
Sbjct: 129 IRLVAGEMGQNEPDQGGQ-RGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179
>Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 39.9 bits (89), Expect = 0.006
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 9/172 (5%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
G SGLG A A RL +G + + + G E +A K L C P DVT + VQ
Sbjct: 17 GGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK-LGNNCVFA-PADVTSEKDVQT- 73
Query: 219 RKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKY------EWMTASMIESPVHVNLLGAMRV 377
L + K K+ + VN AG+ K + T + + VNL+G V
Sbjct: 74 ---ALALAKG--KFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128
Query: 378 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALT 533
I E+ + + + + IIN S + AAYSASK G+ +T
Sbjct: 129 IRLVAGEMGQNEPDQGGQ-RGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179
>U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide binding
protein protein.
Length = 261
Score = 39.9 bits (89), Expect = 0.006
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 9/172 (5%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
G SGLG A A RL +G + + + G E +A K L C P DVT + VQ
Sbjct: 17 GGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK-LGNNCVFA-PADVTSEKDVQT- 73
Query: 219 RKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKY------EWMTASMIESPVHVNLLGAMRV 377
L + K K+ + VN AG+ K + T + + VNL+G V
Sbjct: 74 ---ALALAKG--KFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128
Query: 378 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALT 533
I E+ + + + + IIN S + AAYSASK G+ +T
Sbjct: 129 IRLVAGEMGQNEPDQGGQ-RGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179
>U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 261
Score = 39.9 bits (89), Expect = 0.006
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 9/172 (5%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
G SGLG A A RL +G + + + G E +A K L C P DVT + VQ
Sbjct: 17 GGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK-LGNNCVFA-PADVTSEKDVQT- 73
Query: 219 RKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKY------EWMTASMIESPVHVNLLGAMRV 377
L + K K+ + VN AG+ K + T + + VNL+G V
Sbjct: 74 ---ALALAKG--KFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128
Query: 378 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALT 533
I E+ + + + + IIN S + AAYSASK G+ +T
Sbjct: 129 IRLVAGEMGQNEPDQGGQ-RGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179
>M29037-1|AAB17014.1| 214|Homo sapiens 17 beta-hydroxysteroid
dehydrogenase protein.
Length = 214
Score = 39.9 bits (89), Expect = 0.006
Identities = 49/175 (28%), Positives = 76/175 (43%), Gaps = 9/175 (5%)
Frame = +3
Query: 45 GCDSGLGWAVAARLA---REGFITIAGMH----KGIETEAAKAL--EKLCAHTFPLDVTR 197
GC SG+G +A LA + F A + +G EAA+AL + LDV
Sbjct: 10 GCSSGIGLHLAIHLALDPSQSFKVYATLRDLKTQGRLWEAARALACPQGSLERLQLDVRN 69
Query: 198 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 377
S+ R+ V + + +V N G+ +G + + S + VN++G +RV
Sbjct: 70 SSSLAAARERV-------TEGRVDVLVCNTGLGLLGP---LGEDAVASVLDVNVVGTVRV 119
Query: 378 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ FLP++++ R++ GS GL LP Y ASK L L L
Sbjct: 120 LQDFLPDMKRPG-------SGRVLVTGSMGGLMGLPFNDVYCASKFALEGLCESL 167
>CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein.
Length = 261
Score = 39.9 bits (89), Expect = 0.006
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 9/172 (5%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
G SGLG A A RL +G + + + G E +A K L C P DVT + VQ
Sbjct: 17 GGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK-LGNNCVFA-PADVTSEKDVQT- 73
Query: 219 RKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKY------EWMTASMIESPVHVNLLGAMRV 377
L + K K+ + VN AG+ K + T + + VNL+G V
Sbjct: 74 ---ALALAKG--KFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128
Query: 378 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALT 533
I E+ + + + + IIN S + AAYSASK G+ +T
Sbjct: 129 IRLVAGEMGQNEPDQGGQ-RGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179
>BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 39.9 bits (89), Expect = 0.006
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 9/172 (5%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
G SGLG A A RL +G + + + G E +A K L C P DVT + VQ
Sbjct: 17 GGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK-LGNNCVFA-PADVTSEKDVQT- 73
Query: 219 RKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKY------EWMTASMIESPVHVNLLGAMRV 377
L + K K+ + VN AG+ K + T + + VNL+G V
Sbjct: 74 ---ALALAKG--KFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128
Query: 378 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALT 533
I E+ + + + + IIN S + AAYSASK G+ +T
Sbjct: 129 IRLVAGEMGQNEPDQGGQ-RGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179
>BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 39.9 bits (89), Expect = 0.006
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 9/172 (5%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
G SGLG A A RL +G + + + G E +A K L C P DVT + VQ
Sbjct: 17 GGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK-LGNNCVFA-PADVTSEKDVQT- 73
Query: 219 RKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKY------EWMTASMIESPVHVNLLGAMRV 377
L + K K+ + VN AG+ K + T + + VNL+G V
Sbjct: 74 ---ALALAKG--KFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128
Query: 378 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALT 533
I E+ + + + + IIN S + AAYSASK G+ +T
Sbjct: 129 IRLVAGEMGQNEPDQGGQ-RGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179
>AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain type
dehydrogenase/reductase protein.
Length = 261
Score = 39.9 bits (89), Expect = 0.006
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 9/172 (5%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
G SGLG A A RL +G + + + G E +A K L C P DVT + VQ
Sbjct: 17 GGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK-LGNNCVFA-PADVTSEKDVQT- 73
Query: 219 RKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKY------EWMTASMIESPVHVNLLGAMRV 377
L + K K+ + VN AG+ K + T + + VNL+G V
Sbjct: 74 ---ALALAKG--KFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128
Query: 378 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALT 533
I E+ + + + + IIN S + AAYSASK G+ +T
Sbjct: 129 IRLVAGEMGQNEPDQGGQ-RGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179
>AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain
alcohol dehydrogenase protein.
Length = 260
Score = 39.9 bits (89), Expect = 0.006
Identities = 38/163 (23%), Positives = 69/163 (42%), Gaps = 1/163 (0%)
Frame = +3
Query: 57 GLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLT 236
G+G+A+A RLA++G + K + A A + + V V ++ + V
Sbjct: 25 GIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVAM 84
Query: 237 VLKDNPKYKFHAVVNNAGVMT-VGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTA 413
+K + +V+NA V G +T + + + +N+ + A +PE+ K
Sbjct: 85 AVKLHG--GIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTKAVVPEMEK-- 140
Query: 414 IETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ ++ V S P P F+ Y+ SK L LT+ L
Sbjct: 141 -----RGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTL 178
>AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 39.9 bits (89), Expect = 0.006
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 9/172 (5%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
G SGLG A A RL +G + + + G E +A K L C P DVT + VQ
Sbjct: 17 GGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK-LGNNCVFA-PADVTSEKDVQT- 73
Query: 219 RKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKY------EWMTASMIESPVHVNLLGAMRV 377
L + K K+ + VN AG+ K + T + + VNL+G V
Sbjct: 74 ---ALALAKG--KFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128
Query: 378 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALT 533
I E+ + + + + IIN S + AAYSASK G+ +T
Sbjct: 129 IRLVAGEMGQNEPDQGGQ-RGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179
>AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 39.9 bits (89), Expect = 0.006
Identities = 51/172 (29%), Positives = 73/172 (42%), Gaps = 9/172 (5%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
G SGLG A A RL +G + + + G E +A K L C P DVT + VQ
Sbjct: 17 GGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKK-LGNNCVFA-PADVTSEKDVQT- 73
Query: 219 RKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKY------EWMTASMIESPVHVNLLGAMRV 377
L + K K+ + VN AG+ K + T + + VNL+G V
Sbjct: 74 ---ALALAKG--KFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128
Query: 378 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALT 533
I E+ + + + + IIN S + AAYSASK G+ +T
Sbjct: 129 IRLVAGEMGQNEPDQGGQ-RGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179
>U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein.
Length = 280
Score = 39.5 bits (88), Expect = 0.008
Identities = 44/169 (26%), Positives = 71/169 (42%), Gaps = 3/169 (1%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLD--VTRVESVQEF 218
G SG+G+A+A RLAR+G + K + +A+ KL + V V ++
Sbjct: 43 GSTSGIGFAIARRLARDGAHVVISSRK--QQNVDRAMAKLQGEGLSVAGIVCHVGKAEDR 100
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGV-MTVGKYEWMTASMIESPVHVNLLGAMRVISAFLP 395
+ V L+ F +V +AGV VG + + + + VN+ ++S LP
Sbjct: 101 EQLVAKALEHCGGVDF--LVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLP 158
Query: 396 EIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ + +I V S P+ A Y+ SK L LTR L
Sbjct: 159 YMENR--------RGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTL 199
>BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 39.5 bits (88), Expect = 0.008
Identities = 40/160 (25%), Positives = 65/160 (40%), Gaps = 4/160 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIA-GMHKGIETEAAKALEKLCA---HTFPLDVTRVESVQ 212
G SGLG +A + AR G + + ++K E K + A H + D ++ E V
Sbjct: 47 GAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCDCSQKEGVY 106
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
V + D ++NNAG++T K+ ++E VN + AFL
Sbjct: 107 RVADQVKKEVGD-----VSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFL 161
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 512
P + + ++ + S GL + A Y ASK
Sbjct: 162 PAM-------IANDHGHLVCISSSAGLSGVNGLADYCASK 194
>BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 39.5 bits (88), Expect = 0.008
Identities = 40/160 (25%), Positives = 65/160 (40%), Gaps = 4/160 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIA-GMHKGIETEAAKALEKLCA---HTFPLDVTRVESVQ 212
G SGLG +A + AR G + + ++K E K + A H + D ++ E V
Sbjct: 47 GAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCDCSQKEGVY 106
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
V + D ++NNAG++T K+ ++E VN + AFL
Sbjct: 107 RVADQVKKEVGD-----VSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFL 161
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 512
P + + ++ + S GL + A Y ASK
Sbjct: 162 PAM-------IANDHGHLVCISSSAGLSGVNGLADYCASK 194
>BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein.
Length = 271
Score = 39.5 bits (88), Expect = 0.008
Identities = 44/169 (26%), Positives = 71/169 (42%), Gaps = 3/169 (1%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLD--VTRVESVQEF 218
G SG+G+A+A RLAR+G + K + +A+ KL + V V ++
Sbjct: 34 GSTSGIGFAIARRLARDGAHVVISSRK--QQNVDRAMAKLQGEGLSVAGIVCHVGKAEDR 91
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGV-MTVGKYEWMTASMIESPVHVNLLGAMRVISAFLP 395
+ V L+ F +V +AGV VG + + + + VN+ ++S LP
Sbjct: 92 EQLVAKALEHCGGVDF--LVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLP 149
Query: 396 EIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ + +I V S P+ A Y+ SK L LTR L
Sbjct: 150 YMENR--------RGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTL 190
>BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 protein.
Length = 300
Score = 39.5 bits (88), Expect = 0.008
Identities = 44/169 (26%), Positives = 71/169 (42%), Gaps = 3/169 (1%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLD--VTRVESVQEF 218
G SG+G+A+A RLAR+G + K + +A+ KL + V V ++
Sbjct: 43 GSTSGIGFAIARRLARDGAHVVISSRK--QQNVDRAMAKLQGEGLSVAGIVCHVGKAEDR 100
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGV-MTVGKYEWMTASMIESPVHVNLLGAMRVISAFLP 395
+ V L+ F +V +AGV VG + + + + VN+ ++S LP
Sbjct: 101 EQLVAKALEHCGGVDF--LVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLP 158
Query: 396 EIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ + +I V S P+ A Y+ SK L LTR L
Sbjct: 159 YMENR--------RGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTL 199
>AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ33105 fis, clone TRACH2000926, weakly similar to
PROBABLE OXIDOREDUCTASE EPHD (EC 1.-.-.-). ).
Length = 231
Score = 39.5 bits (88), Expect = 0.008
Identities = 40/160 (25%), Positives = 65/160 (40%), Gaps = 4/160 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIA-GMHKGIETEAAKALEKLCA---HTFPLDVTRVESVQ 212
G SGLG +A + AR G + + ++K E K + A H + D ++ E V
Sbjct: 47 GAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCDCSQKEGVY 106
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
V + D ++NNAG++T K+ ++E VN + AFL
Sbjct: 107 RVADQVKKEVGD-----VSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFL 161
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 512
P + + ++ + S GL + A Y ASK
Sbjct: 162 PAM-------IANDHGHLVCISSSAGLSGVNGLADYCASK 194
>AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 280
Score = 39.5 bits (88), Expect = 0.008
Identities = 44/169 (26%), Positives = 71/169 (42%), Gaps = 3/169 (1%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLD--VTRVESVQEF 218
G SG+G+A+A RLAR+G + K + +A+ KL + V V ++
Sbjct: 43 GSTSGIGFAIARRLARDGAHVVISSRK--QQNVDRAMAKLQGEGLSVAGIVCHVGKAEDR 100
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGV-MTVGKYEWMTASMIESPVHVNLLGAMRVISAFLP 395
+ V L+ F +V +AGV VG + + + + VN+ ++S LP
Sbjct: 101 EQLVAKALEHCGGVDF--LVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLP 158
Query: 396 EIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ + +I V S P+ A Y+ SK L LTR L
Sbjct: 159 YMENR--------RGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTL 199
>BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein.
Length = 300
Score = 38.3 bits (85), Expect = 0.017
Identities = 45/160 (28%), Positives = 65/160 (40%), Gaps = 4/160 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAR-EGFITIAGMHK-GIETEAAKALEKLCA--HTFPLDVTRVESVQ 212
G G+G A A+ + + + ++K G+E AAK + L A HTF +D + E +
Sbjct: 43 GAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC-KGLGAKVHTFVVDCSNREDIY 101
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
K + D +VNNAGV+ IE VN+L AFL
Sbjct: 102 SSAKNCKAEIGD-----VSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFL 156
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 512
P + T I+ V S G +P AY +SK
Sbjct: 157 PAM-------TKNNHGHIVTVASAAGHVSVPFLLAYCSSK 189
>X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid
dehydrogenase protein.
Length = 736
Score = 37.9 bits (84), Expect = 0.023
Identities = 48/173 (27%), Positives = 73/173 (42%), Gaps = 7/173 (4%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIA----GMHKGI---ETEAAKALEKLCAHTFPLDVTRVE 203
G +GLG A A A G + + G KG+ A K +E++ V +
Sbjct: 16 GAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGKA-VANYD 74
Query: 204 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 383
SV+E K V T L + + VVNNAG++ + ++ + V+L G+ +V
Sbjct: 75 SVEEGEKVVKTAL--DAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTR 132
Query: 384 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
A ++K + RII S G+ A YSA+K GL L L
Sbjct: 133 AAWEHMKK-------QKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSL 178
>U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 3 protein.
Length = 310
Score = 37.9 bits (84), Expect = 0.023
Identities = 42/172 (24%), Positives = 75/172 (43%), Gaps = 6/172 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEA-AKALEKLCAHTFPL---DVTRVESVQ 212
G G+G A + LA+ G + + EA A +E+ + + D T+ + +
Sbjct: 55 GAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTK-DDIY 113
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMT--VGKYEWMTASMIESPVHVNLLGAMRVISA 386
E K L L+ +VNN G++ + + I+S +H N+ +++
Sbjct: 114 EHIKEKLAGLE------IGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQL 167
Query: 387 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
L + S+ K I+N+ S L P P ++ YSASKA + A ++ L
Sbjct: 168 ILKHME-------SRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKAL 212
>CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein.
Length = 310
Score = 37.9 bits (84), Expect = 0.023
Identities = 42/172 (24%), Positives = 75/172 (43%), Gaps = 6/172 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEA-AKALEKLCAHTFPL---DVTRVESVQ 212
G G+G A + LA+ G + + EA A +E+ + + D T+ + +
Sbjct: 55 GAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTK-DDIY 113
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMT--VGKYEWMTASMIESPVHVNLLGAMRVISA 386
E K L L+ +VNN G++ + + I+S +H N+ +++
Sbjct: 114 EHIKEKLAGLE------IGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQL 167
Query: 387 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
L + S+ K I+N+ S L P P ++ YSASKA + A ++ L
Sbjct: 168 ILKHME-------SRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKAL 212
>BT019371-1|AAV38178.1| 260|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 260
Score = 37.9 bits (84), Expect = 0.023
Identities = 42/172 (24%), Positives = 75/172 (43%), Gaps = 6/172 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEA-AKALEKLCAHTFPL---DVTRVESVQ 212
G G+G A + LA+ G + + EA A +E+ + + D T+ + +
Sbjct: 55 GAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTK-DDIY 113
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMT--VGKYEWMTASMIESPVHVNLLGAMRVISA 386
E K L L+ +VNN G++ + + I+S +H N+ +++
Sbjct: 114 EHIKEKLAGLE------IGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQL 167
Query: 387 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
L + S+ K I+N+ S L P P ++ YSASKA + A ++ L
Sbjct: 168 ILKHME-------SRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKAL 212
>BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 37.9 bits (84), Expect = 0.023
Identities = 42/172 (24%), Positives = 75/172 (43%), Gaps = 6/172 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEA-AKALEKLCAHTFPL---DVTRVESVQ 212
G G+G A + LA+ G + + EA A +E+ + + D T+ + +
Sbjct: 55 GAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTK-DDIY 113
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMT--VGKYEWMTASMIESPVHVNLLGAMRVISA 386
E K L L+ +VNN G++ + + I+S +H N+ +++
Sbjct: 114 EHIKEKLAGLE------IGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQL 167
Query: 387 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
L + S+ K I+N+ S L P P ++ YSASKA + A ++ L
Sbjct: 168 ILKHME-------SRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKAL 212
>BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 12 protein.
Length = 312
Score = 37.9 bits (84), Expect = 0.023
Identities = 19/73 (26%), Positives = 38/73 (52%)
Frame = +3
Query: 327 SMIESPVHVNLLGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSA 506
++I+ +++N+L ++ LP + + K I+N+ S G+ P+P YSA
Sbjct: 152 NVIKKMININILSVCKMTQLVLPGM-------VERSKGAILNISSGSGMLPVPLLTIYSA 204
Query: 507 SKAGLWALTRCLH 545
+K + ++CLH
Sbjct: 205 TKTFVDFFSQCLH 217
>BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 4 protein.
Length = 736
Score = 37.9 bits (84), Expect = 0.023
Identities = 48/173 (27%), Positives = 73/173 (42%), Gaps = 7/173 (4%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIA----GMHKGI---ETEAAKALEKLCAHTFPLDVTRVE 203
G +GLG A A A G + + G KG+ A K +E++ V +
Sbjct: 16 GAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGKA-VANYD 74
Query: 204 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 383
SV+E K V T L + + VVNNAG++ + ++ + V+L G+ +V
Sbjct: 75 SVEEGEKVVKTAL--DAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTR 132
Query: 384 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
A ++K + RII S G+ A YSA+K GL L L
Sbjct: 133 AAWEHMKK-------QKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSL 178
>AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 37.9 bits (84), Expect = 0.023
Identities = 42/172 (24%), Positives = 75/172 (43%), Gaps = 6/172 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEA-AKALEKLCAHTFPL---DVTRVESVQ 212
G G+G A + LA+ G + + EA A +E+ + + D T+ + +
Sbjct: 55 GAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTK-DDIY 113
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMT--VGKYEWMTASMIESPVHVNLLGAMRVISA 386
E K L L+ +VNN G++ + + I+S +H N+ +++
Sbjct: 114 EHIKEKLAGLE------IGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQL 167
Query: 387 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
L + S+ K I+N+ S L P P ++ YSASKA + A ++ L
Sbjct: 168 ILKHME-------SRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKAL 212
>AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 37.9 bits (84), Expect = 0.023
Identities = 42/172 (24%), Positives = 75/172 (43%), Gaps = 6/172 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEA-AKALEKLCAHTFPL---DVTRVESVQ 212
G G+G A + LA+ G + + EA A +E+ + + D T+ + +
Sbjct: 55 GAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTK-DDIY 113
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMT--VGKYEWMTASMIESPVHVNLLGAMRVISA 386
E K L L+ +VNN G++ + + I+S +H N+ +++
Sbjct: 114 EHIKEKLAGLE------IGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQL 167
Query: 387 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
L + S+ K I+N+ S L P P ++ YSASKA + A ++ L
Sbjct: 168 ILKHME-------SRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKAL 212
>AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase
homolog protein.
Length = 312
Score = 37.9 bits (84), Expect = 0.023
Identities = 19/73 (26%), Positives = 38/73 (52%)
Frame = +3
Query: 327 SMIESPVHVNLLGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSA 506
++I+ +++N+L ++ LP + + K I+N+ S G+ P+P YSA
Sbjct: 152 NVIKKMININILSVCKMTQLVLPGM-------VERSKGAILNISSGSGMLPVPLLTIYSA 204
Query: 507 SKAGLWALTRCLH 545
+K + ++CLH
Sbjct: 205 TKTFVDFFSQCLH 217
>AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens
cDNA FLJ14976 fis, clone THYRO1001406, highly similar to
PUTATIVE STEROID DEHYDROGENASE KIK-I (EC 1.1.1.-). ).
Length = 177
Score = 37.9 bits (84), Expect = 0.023
Identities = 19/73 (26%), Positives = 38/73 (52%)
Frame = +3
Query: 327 SMIESPVHVNLLGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSA 506
++I+ +++N+L ++ LP + + K I+N+ S G+ P+P YSA
Sbjct: 17 NVIKKMININILSVCKMTQLVLPGM-------VERSKGAILNISSGSGMLPVPLLTIYSA 69
Query: 507 SKAGLWALTRCLH 545
+K + ++CLH
Sbjct: 70 TKTFVDFFSQCLH 82
>AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase IV protein.
Length = 736
Score = 37.9 bits (84), Expect = 0.023
Identities = 48/173 (27%), Positives = 73/173 (42%), Gaps = 7/173 (4%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIA----GMHKGI---ETEAAKALEKLCAHTFPLDVTRVE 203
G +GLG A A A G + + G KG+ A K +E++ V +
Sbjct: 16 GAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGKA-VANYD 74
Query: 204 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 383
SV+E K V T L + + VVNNAG++ + ++ + V+L G+ +V
Sbjct: 75 SVEEGEKVVKTAL--DAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTR 132
Query: 384 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
A ++K + RII S G+ A YSA+K GL L L
Sbjct: 133 AAWEHMKK-------QKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSL 178
>AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase protein.
Length = 309
Score = 36.7 bits (81), Expect = 0.053
Identities = 39/160 (24%), Positives = 64/160 (40%), Gaps = 4/160 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIA-GMHKGIETEAAKALEKLCA---HTFPLDVTRVESVQ 212
G SGLG +A + AR G + + ++K E K + A + D ++ E V
Sbjct: 47 GAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVRAYTCDCSQKEGVY 106
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
V + D ++NNAG++T K+ ++E VN + AFL
Sbjct: 107 RVADQVKKEIGD-----VSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFL 161
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 512
P + + ++ + S GL + A Y ASK
Sbjct: 162 PAM-------IANDHGHLVCISSSAGLSGVNGLADYCASK 194
>BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 36.3 bits (80), Expect = 0.070
Identities = 43/170 (25%), Positives = 69/170 (40%), Gaps = 4/170 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
G G+G A A LA G I I+ + ++ A + T + V S +E
Sbjct: 74 GATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVET-DIIVADFSSGREI 132
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGVMTVGK--YEWMTASMIESPVHVNLLGAMRVISAFL 392
+ LKD +VNN GV + ++ + ++VN+ A ++ L
Sbjct: 133 YLPIREALKDKD---VGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMVHVVL 189
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
P + + K I+ + S +P P AA+SASKA L +R L
Sbjct: 190 PGM-------VERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRAL 232
>BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 36.3 bits (80), Expect = 0.070
Identities = 43/170 (25%), Positives = 69/170 (40%), Gaps = 4/170 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
G G+G A A LA G I I+ + ++ A + T + V S +E
Sbjct: 74 GATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVET-DIIVADFSSGREI 132
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGVMTVGK--YEWMTASMIESPVHVNLLGAMRVISAFL 392
+ LKD +VNN GV + ++ + ++VN+ A ++ L
Sbjct: 133 YLPIREALKDKD---VGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMVHVVL 189
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
P + + K I+ + S +P P AA+SASKA L +R L
Sbjct: 190 PGM-------VERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRAL 232
>AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein.
Length = 331
Score = 36.3 bits (80), Expect = 0.070
Identities = 36/128 (28%), Positives = 58/128 (45%), Gaps = 5/128 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETE-AAKAL--EKLCAHTFP--LDVTRVESV 209
G ++G+G A LAR G I + E AAK + E L H LD+ ++S+
Sbjct: 45 GANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLDLASLKSI 104
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
+EF ++ + + ++NNAGVM W T E VN LG + +
Sbjct: 105 REFAAKII-----EEEERVDILINNAGVMRCP--HWTTEDGFEMQFGVNHLGHFLLTNLL 157
Query: 390 LPEIRKTA 413
L +++ +A
Sbjct: 158 LDKLKASA 165
>AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 36.3 bits (80), Expect = 0.070
Identities = 43/170 (25%), Positives = 69/170 (40%), Gaps = 4/170 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
G G+G A A LA G I I+ + ++ A + T + V S +E
Sbjct: 53 GATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVET-DIIVADFSSGREI 111
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGVMTVGK--YEWMTASMIESPVHVNLLGAMRVISAFL 392
+ LKD +VNN GV + ++ + ++VN+ A ++ L
Sbjct: 112 YLPIREALKDKD---VGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMVHVVL 168
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
P + + K I+ + S +P P AA+SASKA L +R L
Sbjct: 169 PGM-------VERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRAL 211
>AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ90397 fis, clone NT2RP2005878, moderately
similar to PUTATIVE STEROID DEHYDROGENASE KIK-I (EC
1.1.1.-). ).
Length = 330
Score = 36.3 bits (80), Expect = 0.070
Identities = 43/170 (25%), Positives = 69/170 (40%), Gaps = 4/170 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
G G+G A A LA G I I+ + ++ A + T + V S +E
Sbjct: 74 GATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVET-DIIVADFSSGREI 132
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGVMTVGK--YEWMTASMIESPVHVNLLGAMRVISAFL 392
+ LKD +VNN GV + ++ + ++VN+ A ++ L
Sbjct: 133 YLPIREALKDKD---VGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMVHVVL 189
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
P + + K I+ + S +P P AA+SASKA L +R L
Sbjct: 190 PGM-------VERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRAL 232
>AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 36.3 bits (80), Expect = 0.070
Identities = 43/170 (25%), Positives = 69/170 (40%), Gaps = 4/170 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
G G+G A A LA G I I+ + ++ A + T + V S +E
Sbjct: 53 GATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVET-DIIVADFSSGREI 111
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGVMTVGK--YEWMTASMIESPVHVNLLGAMRVISAFL 392
+ LKD +VNN GV + ++ + ++VN+ A ++ L
Sbjct: 112 YLPIREALKDKD---VGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMVHVVL 168
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
P + + K I+ + S +P P AA+SASKA L +R L
Sbjct: 169 PGM-------VERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRAL 211
>CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein.
Length = 318
Score = 35.1 bits (77), Expect = 0.16
Identities = 39/144 (27%), Positives = 63/144 (43%), Gaps = 5/144 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG---FITIAGMHKG--IETEAAKALEKLCAHTFPLDVTRVESV 209
G ++G+G A LA+ G ++ + KG + E LD++ +S+
Sbjct: 48 GANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSI 107
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
+ F K L K H ++NNAGVM + Y TA E + VN LG +
Sbjct: 108 RAFAKGFLAEEKH-----LHVLINNAGVM-MCPYS-KTADGFEMHIGVNHLGHFLLTHLL 160
Query: 390 LPEIRKTAIETTSKPKPRIINVGS 461
L +++++A RI+NV S
Sbjct: 161 LEKLKESA-------PSRIVNVSS 177
>BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.16
Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 4/170 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
G G+G A A LA G I I+ + ++ A + T + V S +E
Sbjct: 74 GATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVET-DIIVADFSSGREI 132
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGVMTVGK--YEWMTASMIESPVHVNLLGAMRVISAFL 392
+ LKD +VNN GV + ++ + ++VN+ A ++ L
Sbjct: 133 YLPIREALKDKD---VGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMVHVVL 189
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
P + + K I+ + S +P P AA+SAS+A L +R L
Sbjct: 190 PGM-------VERKKGAIVTISSGSCCKPTPQLAAFSASRAYLDHFSRAL 232
>BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.16
Identities = 42/170 (24%), Positives = 69/170 (40%), Gaps = 4/170 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 218
G G+G A A LA G I I+ + ++ A + T + V S +E
Sbjct: 74 GATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVET-DIIVADFSSGREI 132
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGVMTVGK--YEWMTASMIESPVHVNLLGAMRVISAFL 392
+ LKD +VNN GV + ++ + ++VN+ A ++ L
Sbjct: 133 YLPIREALKDKD---VGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMVHVVL 189
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
P + + K I+ + S +P P AA+SAS+A L +R L
Sbjct: 190 PGM-------VERKKGAIVTISSGSCCKPTPQLAAFSASRAYLDHFSRAL 232
>BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 35.1 bits (77), Expect = 0.16
Identities = 39/144 (27%), Positives = 63/144 (43%), Gaps = 5/144 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG---FITIAGMHKG--IETEAAKALEKLCAHTFPLDVTRVESV 209
G ++G+G A LA+ G ++ + KG + E LD++ +S+
Sbjct: 48 GANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSI 107
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
+ F K L K H ++NNAGVM + Y TA E + VN LG +
Sbjct: 108 RAFAKGFLAEEKH-----LHVLINNAGVM-MCPYS-KTADGFEMHIGVNHLGHFLLTHLL 160
Query: 390 LPEIRKTAIETTSKPKPRIINVGS 461
L +++++A RI+NV S
Sbjct: 161 LEKLKESA-------PSRIVNVSS 177
>BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 35.1 bits (77), Expect = 0.16
Identities = 39/144 (27%), Positives = 63/144 (43%), Gaps = 5/144 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG---FITIAGMHKG--IETEAAKALEKLCAHTFPLDVTRVESV 209
G ++G+G A LA+ G ++ + KG + E LD++ +S+
Sbjct: 48 GANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSI 107
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
+ F K L K H ++NNAGVM + Y TA E + VN LG +
Sbjct: 108 RAFAKGFLAEEKH-----LHVLINNAGVM-MCPYS-KTADGFEMHIGVNHLGHFLLTHLL 160
Query: 390 LPEIRKTAIETTSKPKPRIINVGS 461
L +++++A RI+NV S
Sbjct: 161 LEKLKESA-------PSRIVNVSS 177
>BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein.
Length = 318
Score = 35.1 bits (77), Expect = 0.16
Identities = 39/144 (27%), Positives = 63/144 (43%), Gaps = 5/144 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG---FITIAGMHKG--IETEAAKALEKLCAHTFPLDVTRVESV 209
G ++G+G A LA+ G ++ + KG + E LD++ +S+
Sbjct: 48 GANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSI 107
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
+ F K L K H ++NNAGVM + Y TA E + VN LG +
Sbjct: 108 RAFAKGFLAEEKH-----LHVLINNAGVM-MCPYS-KTADGFEMHIGVNHLGHFLLTHLL 160
Query: 390 LPEIRKTAIETTSKPKPRIINVGS 461
L +++++A RI+NV S
Sbjct: 161 LEKLKESA-------PSRIVNVSS 177
>BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 35.1 bits (77), Expect = 0.16
Identities = 39/144 (27%), Positives = 63/144 (43%), Gaps = 5/144 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG---FITIAGMHKG--IETEAAKALEKLCAHTFPLDVTRVESV 209
G ++G+G A LA+ G ++ + KG + E LD++ +S+
Sbjct: 48 GANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSI 107
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
+ F K L K H ++NNAGVM + Y TA E + VN LG +
Sbjct: 108 RAFAKGFLAEEKH-----LHVLINNAGVM-MCPYS-KTADGFEMHIGVNHLGHFLLTHLL 160
Query: 390 LPEIRKTAIETTSKPKPRIINVGS 461
L +++++A RI+NV S
Sbjct: 161 LEKLKESA-------PSRIVNVSS 177
>AY046280-1|AAK91586.1| 132|Homo sapiens hydroxysteroid
dehydrogenase type 2 protein.
Length = 132
Score = 35.1 bits (77), Expect = 0.16
Identities = 40/145 (27%), Positives = 60/145 (41%), Gaps = 7/145 (4%)
Frame = +3
Query: 48 CDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---HTFPLDVTR---VESV 209
CDSG G A +L GF +A + + + + A L C+ +D+T+ + V
Sbjct: 1 CDSGFGKETAKKLDSMGFTVLATVLE-LNSPGAIELRTCCSPRLRLLQMDLTKPGDISRV 59
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAG-VMTVGKYEWMTASMIESPVHVNLLGAMRVISA 386
EF K T +VNNAG V E + S + VN GA+ +
Sbjct: 60 LEFTKAHTT------STGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKG 113
Query: 387 FLPEIRKTAIETTSKPKPRIINVGS 461
LP +R + + RI+ VGS
Sbjct: 114 LLPLLRSS--------RGRIVTVGS 130
>AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protein
HCBP12 protein.
Length = 318
Score = 35.1 bits (77), Expect = 0.16
Identities = 39/144 (27%), Positives = 63/144 (43%), Gaps = 5/144 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG---FITIAGMHKG--IETEAAKALEKLCAHTFPLDVTRVESV 209
G ++G+G A LA+ G ++ + KG + E LD++ +S+
Sbjct: 48 GANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSI 107
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
+ F K L K H ++NNAGVM + Y TA E + VN LG +
Sbjct: 108 RAFAKGFLAEEKH-----LHVLINNAGVM-MCPYS-KTADGFEMHIGVNHLGHFLLTHLL 160
Query: 390 LPEIRKTAIETTSKPKPRIINVGS 461
L +++++A RI+NV S
Sbjct: 161 LEKLKESA-------PSRIVNVSS 177
>AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated
short-chain dehydrogenase/reductase 1 protein.
Length = 318
Score = 35.1 bits (77), Expect = 0.16
Identities = 39/144 (27%), Positives = 63/144 (43%), Gaps = 5/144 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG---FITIAGMHKG--IETEAAKALEKLCAHTFPLDVTRVESV 209
G ++G+G A LA+ G ++ + KG + E LD++ +S+
Sbjct: 48 GANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSI 107
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
+ F K L K H ++NNAGVM + Y TA E + VN LG +
Sbjct: 108 RAFAKGFLAEEKH-----LHVLINNAGVM-MCPYS-KTADGFEMHIGVNHLGHFLLTHLL 160
Query: 390 LPEIRKTAIETTSKPKPRIINVGS 461
L +++++A RI+NV S
Sbjct: 161 LEKLKESA-------PSRIVNVSS 177
>AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein.
Length = 318
Score = 35.1 bits (77), Expect = 0.16
Identities = 39/144 (27%), Positives = 63/144 (43%), Gaps = 5/144 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG---FITIAGMHKG--IETEAAKALEKLCAHTFPLDVTRVESV 209
G ++G+G A LA+ G ++ + KG + E LD++ +S+
Sbjct: 48 GANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSI 107
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
+ F K L K H ++NNAGVM + Y TA E + VN LG +
Sbjct: 108 RAFAKGFLAEEKH-----LHVLINNAGVM-MCPYS-KTADGFEMHIGVNHLGHFLLTHLL 160
Query: 390 LPEIRKTAIETTSKPKPRIINVGS 461
L +++++A RI+NV S
Sbjct: 161 LEKLKESA-------PSRIVNVSS 177
>DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 11
protein.
Length = 171
Score = 34.7 bits (76), Expect = 0.21
Identities = 34/128 (26%), Positives = 57/128 (44%), Gaps = 5/128 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG---FITIAGMHKG--IETEAAKALEKLCAHTFPLDVTRVESV 209
G ++G+G A LA+ G ++ + KG + E LD++ +S+
Sbjct: 48 GANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSI 107
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
+ F K L K H ++NNAGVM + Y TA E + VN LG +
Sbjct: 108 RAFAKGFLAEEKH-----LHVLINNAGVM-MCPYS-KTADGFEMHIGVNHLGHFLLTHLL 160
Query: 390 LPEIRKTA 413
L +++++A
Sbjct: 161 LEKLKESA 168
>BC026024-1|AAH26024.1| 312|Homo sapiens DHRS12 protein protein.
Length = 312
Score = 34.7 bits (76), Expect = 0.21
Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 2/141 (1%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKA--LEKLCAHTFPLDVTRVESVQEF 218
G +SG+G A A +A+ G E A+ + + L + + ++
Sbjct: 42 GGNSGIGKATALEIAKRGGTVHLVCRDQAPAEDARGEIIRESGNQNIFLHIVDLSDPKQI 101
Query: 219 RKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPE 398
K+V ++ +K H ++NNAG M V K E +T +E N LG + + +P
Sbjct: 102 WKFVENFKQE---HKLHVLINNAGCM-VNKRE-LTEDGLEKNFAANTLGVYILTTGLIPV 156
Query: 399 IRKTAIETTSKPKPRIINVGS 461
+ K + PR+I V S
Sbjct: 157 LEK-------EHDPRVITVSS 170
>CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein.
Length = 325
Score = 33.9 bits (74), Expect = 0.37
Identities = 25/90 (27%), Positives = 40/90 (44%)
Frame = +3
Query: 273 VVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTAIETTSKPKPRIIN 452
+VNNAG+ G T + + + N G + + A LP + K + + I+
Sbjct: 139 LVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIK-------RRQGHIVA 191
Query: 453 VGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ S G +P +AY+ASK A CL
Sbjct: 192 ISSIQGKMSIPFRSAYAASKHATQAFFDCL 221
>BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 33.9 bits (74), Expect = 0.37
Identities = 25/90 (27%), Positives = 40/90 (44%)
Frame = +3
Query: 273 VVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTAIETTSKPKPRIIN 452
+VNNAG+ G T + + + N G + + A LP + K + + I+
Sbjct: 139 LVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIK-------RRQGHIVA 191
Query: 453 VGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ S G +P +AY+ASK A CL
Sbjct: 192 ISSIQGKMSIPFRSAYAASKHATQAFFDCL 221
>BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 33.9 bits (74), Expect = 0.37
Identities = 25/90 (27%), Positives = 40/90 (44%)
Frame = +3
Query: 273 VVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTAIETTSKPKPRIIN 452
+VNNAG+ G T + + + N G + + A LP + K + + I+
Sbjct: 139 LVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIK-------RRQGHIVA 191
Query: 453 VGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ S G +P +AY+ASK A CL
Sbjct: 192 ISSIQGKMSIPFRSAYAASKHATQAFFDCL 221
>BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 like 2 protein.
Length = 230
Score = 33.9 bits (74), Expect = 0.37
Identities = 36/163 (22%), Positives = 66/163 (40%), Gaps = 1/163 (0%)
Frame = +3
Query: 57 GLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLT 236
G+G+A+A RLA++ + K + A A + + V V ++ + V
Sbjct: 41 GIGFAIARRLAQDRAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVAM 100
Query: 237 VLKDNPKYKFHAVVNNAGVMT-VGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTA 413
+K + +V+NA V G +T + + + +N+ + A +PE+ K
Sbjct: 101 AVKLHG--GIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTKAVVPEMEK-- 156
Query: 414 IETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ ++ V S P P F+ Y+ SK L L L
Sbjct: 157 -----RGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTL 194
>AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein.
Length = 310
Score = 33.9 bits (74), Expect = 0.37
Identities = 25/90 (27%), Positives = 40/90 (44%)
Frame = +3
Query: 273 VVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTAIETTSKPKPRIIN 452
+VNNAG+ G T + + + N G + + A LP + K + + I+
Sbjct: 124 LVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIK-------RRQGHIVA 176
Query: 453 VGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ S G +P +AY+ASK A CL
Sbjct: 177 ISSIQGKMSIPFRSAYAASKHATQAFFDCL 206
>AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein.
Length = 291
Score = 33.9 bits (74), Expect = 0.37
Identities = 25/90 (27%), Positives = 40/90 (44%)
Frame = +3
Query: 273 VVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTAIETTSKPKPRIIN 452
+VNNAG+ G T + + + N G + + A LP + K + + I+
Sbjct: 144 LVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIK-------RRQGHIVA 196
Query: 453 VGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
+ S G +P +AY+ASK A CL
Sbjct: 197 ISSIQGKMSIPFRSAYAASKHATQAFFDCL 226
>AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens
cDNA PSEC0082 fis, clone NT2RP2004966, highly similar to
Retinol dehydrogenase 13 (EC 1.1.1.-). ).
Length = 331
Score = 33.5 bits (73), Expect = 0.49
Identities = 35/128 (27%), Positives = 57/128 (44%), Gaps = 5/128 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETE-AAKAL--EKLCAHTFP--LDVTRVESV 209
G ++G+G A LAR G I + E AAK + E L H LD+ ++S+
Sbjct: 45 GANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLDLASLKSI 104
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
+ F ++ + + ++NNAGVM W T E VN LG + +
Sbjct: 105 RVFAAKII-----EEEERVDILINNAGVMRCP--HWTTEDGFEMQFGVNHLGHFLLTNLL 157
Query: 390 LPEIRKTA 413
L +++ +A
Sbjct: 158 LDKLKASA 165
>CR381696-3|CAI95411.1| 266|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 266
Score = 33.1 bits (72), Expect = 0.65
Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 5/127 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVT----RVESV 209
G G+G++ A LAR G + IAG + +++A + + K+ T V + S+
Sbjct: 127 GGTDGIGYSTAKHLARLGMHVIIAGNN---DSKAKQVVSKIKEETLNDKVEFLYCDLASM 183
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
R++V K H ++NNAGVM V + + T E +N LG + +
Sbjct: 184 TSIRQFVQKFKMK--KIPLHVLINNAGVMMVPQRK--TRDGFEEHFGLNYLGHFLLTNLL 239
Query: 390 LPEIRKT 410
L ++++
Sbjct: 240 LDTLKES 246
>CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 33.1 bits (72), Expect = 0.65
Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 5/127 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVT----RVESV 209
G G+G++ A LAR G + IAG + +++A + + K+ T V + S+
Sbjct: 50 GGTDGIGYSTAKHLARLGMHVIIAGNN---DSKAKQVVSKIKEETLNDKVEFLYCDLASM 106
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
R++V K H ++NNAGVM V + + T E +N LG + +
Sbjct: 107 TSIRQFVQKFKMK--KIPLHVLINNAGVMMVPQRK--TRDGFEEHFGLNYLGHFLLTNLL 162
Query: 390 LPEIRKT 410
L ++++
Sbjct: 163 LDTLKES 169
>BX649443-3|CAI95432.1| 266|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 266
Score = 33.1 bits (72), Expect = 0.65
Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 5/127 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVT----RVESV 209
G G+G++ A LAR G + IAG + +++A + + K+ T V + S+
Sbjct: 127 GGTDGIGYSTAKHLARLGMHVIIAGNN---DSKAKQVVSKIKEETLNDKVEFLYCDLASM 183
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
R++V K H ++NNAGVM V + + T E +N LG + +
Sbjct: 184 TSIRQFVQKFKMK--KIPLHVLINNAGVMMVPQRK--TRDGFEEHFGLNYLGHFLLTNLL 239
Query: 390 LPEIRKT 410
L ++++
Sbjct: 240 LDTLKES 246
>BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 33.1 bits (72), Expect = 0.65
Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 5/127 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVT----RVESV 209
G G+G++ A LAR G + IAG + +++A + + K+ T V + S+
Sbjct: 50 GGTDGIGYSTAKHLARLGMHVIIAGNN---DSKAKQVVSKIKEETLNDKVEFLYCDLASM 106
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
R++V K H ++NNAGVM V + + T E +N LG + +
Sbjct: 107 TSIRQFVQKFKMK--KIPLHVLINNAGVMMVPQRK--TRDGFEEHFGLNYLGHFLLTNLL 162
Query: 390 LPEIRKT 410
L ++++
Sbjct: 163 LDTLKES 169
>BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 330
Score = 33.1 bits (72), Expect = 0.65
Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 5/127 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVT----RVESV 209
G G+G++ A LAR G + IAG + +++A + + K+ T V + S+
Sbjct: 50 GGTDGIGYSTAKHLARLGMHVIIAGNN---DSKAKQVVSKIKEETLNDKVEFLYCDLASM 106
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
R++V K H ++NNAGVM V + + T E +N LG + +
Sbjct: 107 TSIRQFVQKFKMK--KIPLHVLINNAGVMMVPQRK--TRDGFEEHFGLNYLGHFLLTNLL 162
Query: 390 LPEIRKT 410
L ++++
Sbjct: 163 LDTLKES 169
>BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein.
Length = 330
Score = 33.1 bits (72), Expect = 0.65
Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 5/127 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVT----RVESV 209
G G+G++ A LAR G + IAG + +++A + + K+ T V + S+
Sbjct: 50 GGTDGIGYSTAKHLARLGMHVIIAGNN---DSKAKQVVSKIKEETLNDKVEFLYCDLASM 106
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
R++V K H ++NNAGVM V + + T E +N LG + +
Sbjct: 107 TSIRQFVQKFKMK--KIPLHVLINNAGVMMVPQRK--TRDGFEEHFGLNYLGHFLLTNLL 162
Query: 390 LPEIRKT 410
L ++++
Sbjct: 163 LDTLKES 169
>AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein.
Length = 330
Score = 33.1 bits (72), Expect = 0.65
Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 5/127 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVT----RVESV 209
G G+G++ A LAR G + IAG + +++A + + K+ T V + S+
Sbjct: 50 GGTDGIGYSTAKHLARLGMHVIIAGNN---DSKAKQVVSKIKEETLNDKVEFLYCDLASM 106
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
R++V K H ++NNAGVM V + + T E +N LG + +
Sbjct: 107 TSIRQFVQKFKMK--KIPLHVLINNAGVMMVPQRK--TRDGFEEHFGLNYLGHFLLTNLL 162
Query: 390 LPEIRKT 410
L ++++
Sbjct: 163 LDTLKES 169
>AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase
protein.
Length = 330
Score = 33.1 bits (72), Expect = 0.65
Identities = 33/127 (25%), Positives = 59/127 (46%), Gaps = 5/127 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVT----RVESV 209
G G+G++ A LAR G + IAG + +++A + + K+ T V + S+
Sbjct: 50 GGTDGIGYSTAKHLARLGMHVIIAGNN---DSKAKQVVSKIKEETLNDKVEFLYCDLASM 106
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
R++V K H ++NNAGVM V + + T E +N LG + +
Sbjct: 107 TSIRQFVQKFKMK--KIPLHVLINNAGVMMVPQRK--TRDGFEEHFGLNYLGHFLLTNLL 162
Query: 390 LPEIRKT 410
L ++++
Sbjct: 163 LDTLKES 169
>BC009825-1|AAH09825.1| 271|Homo sapiens dehydrogenase/reductase
(SDR family) member 12 protein.
Length = 271
Score = 31.9 bits (69), Expect = 1.5
Identities = 22/69 (31%), Positives = 34/69 (49%)
Frame = +3
Query: 255 KYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTAIETTSKP 434
++K H ++NNAG M V K E +T +E N LG + + +P + K +
Sbjct: 67 EHKLHVLINNAGCM-VNKRE-LTEDGLEKNFAANTLGVYILTTGLIPVLEK-------EH 117
Query: 435 KPRIINVGS 461
PR+I V S
Sbjct: 118 DPRVITVSS 126
>AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein.
Length = 245
Score = 31.9 bits (69), Expect = 1.5
Identities = 41/164 (25%), Positives = 72/164 (43%), Gaps = 2/164 (1%)
Frame = +3
Query: 57 GLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA-HTFPLDVTRVESVQEFRKYVL 233
G+G A A AREG IA I + LEK T LDVT+ + + +F V
Sbjct: 17 GIGQAAALAFAREGAKVIA---TDINESKLQELEKYPGIQTRVLDVTKKKQIDQFASEVE 73
Query: 234 TVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTA 413
+ + + V++ V+ + +W + +++N+ +I AFLP++
Sbjct: 74 RL---DVLFNVAGFVHHGTVLDCEEKDW------DFSMNLNVRSMYLMIKAFLPKM---- 120
Query: 414 IETTSKPKPRIINVGS-HCGLQPLPAFAAYSASKAGLWALTRCL 542
++ IIN+ S ++ + YS +KA + LT+ L
Sbjct: 121 ---LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSL 161
>AL162377-1|CAI13427.1| 242|Homo sapiens dehydrogenase/reductase
(SDR family) member 12 protein.
Length = 242
Score = 31.9 bits (69), Expect = 1.5
Identities = 22/69 (31%), Positives = 34/69 (49%)
Frame = +3
Query: 255 KYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTAIETTSKP 434
++K H ++NNAG M V K E +T +E N LG + + +P + K +
Sbjct: 67 EHKLHVLINNAGCM-VNKRE-LTEDGLEKNFAANTLGVYILTTGLIPVLEK-------EH 117
Query: 435 KPRIINVGS 461
PR+I V S
Sbjct: 118 DPRVITVSS 126
>AL136525-2|CAH70586.1| 242|Homo sapiens dehydrogenase/reductase
(SDR family) member 12 protein.
Length = 242
Score = 31.9 bits (69), Expect = 1.5
Identities = 22/69 (31%), Positives = 34/69 (49%)
Frame = +3
Query: 255 KYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTAIETTSKP 434
++K H ++NNAG M V K E +T +E N LG + + +P + K +
Sbjct: 67 EHKLHVLINNAGCM-VNKRE-LTEDGLEKNFAANTLGVYILTTGLIPVLEK-------EH 117
Query: 435 KPRIINVGS 461
PR+I V S
Sbjct: 118 DPRVITVSS 126
>AK126701-1|BAC86649.1| 173|Homo sapiens protein ( Homo sapiens
cDNA FLJ44747 fis, clone BRACE3028998, moderately
similar to D-beta-hydroxybutyrate dehydrogenase
precursor (EC 1.1.1.30). ).
Length = 173
Score = 31.9 bits (69), Expect = 1.5
Identities = 12/24 (50%), Positives = 17/24 (70%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAG 116
GCDSG G+++A L +GF+ AG
Sbjct: 145 GCDSGFGFSLAKHLHSKGFLVFAG 168
>AK023701-1|BAB14646.1| 242|Homo sapiens protein ( Homo sapiens
cDNA FLJ13639 fis, clone PLACE1011219, weakly similar to
PROBABLE OXIDOREDUCTASE (EC 1.-.-.-). ).
Length = 242
Score = 31.9 bits (69), Expect = 1.5
Identities = 22/69 (31%), Positives = 34/69 (49%)
Frame = +3
Query: 255 KYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTAIETTSKP 434
++K H ++NNAG M V K E +T +E N LG + + +P + K +
Sbjct: 67 EHKLHVLINNAGCM-VNKRE-LTEDGLEKNFAANTLGVYILTTGLIPVLEK-------EH 117
Query: 435 KPRIINVGS 461
PR+I V S
Sbjct: 118 DPRVITVSS 126
>BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 12
(all-trans/9-cis/11-cis) protein.
Length = 316
Score = 31.5 bits (68), Expect = 2.0
Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 5/128 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG---FITIAGMHKGIETEAAKALEKLCAHTF--PLDVTRVESV 209
G ++G+G A LA G +I + KG + ++ + LD++ +S+
Sbjct: 46 GANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKNSQVLVRKLDLSDTKSI 105
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
+ F + L K + H ++NNAGVM + Y TA E+ + VN LG +
Sbjct: 106 RAFAEGFLAEEK-----QLHILINNAGVM-MCPYS-KTADGFETHLGVNHLGHFLLTYLL 158
Query: 390 LPEIRKTA 413
L +++ +A
Sbjct: 159 LEQLKVSA 166
>AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic
reticulum-associated amyloid beta peptide-binding
protein protein.
Length = 196
Score = 31.5 bits (68), Expect = 2.0
Identities = 39/137 (28%), Positives = 56/137 (40%), Gaps = 7/137 (5%)
Frame = +3
Query: 144 AKALEKLCAHTFPLDVTRVESVQEFRKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKY--- 311
AK L C P DVT + VQ L + K K+ + VN AG+ K
Sbjct: 1 AKKLGNNCVFA-PADVTSEKDVQT----ALALAKG--KFGRVDVAVNCAGIAVASKTYNL 53
Query: 312 ---EWMTASMIESPVHVNLLGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPL 482
+ T + + VNL+G VI E+ + + + + IIN S +
Sbjct: 54 KKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQ-RGVIINTASVAAFEGQ 112
Query: 483 PAFAAYSASKAGLWALT 533
AAYSASK G+ +T
Sbjct: 113 VGQAAYSASKGGIVGMT 129
>BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 30.7 bits (66), Expect = 3.5
Identities = 40/162 (24%), Positives = 71/162 (43%), Gaps = 2/162 (1%)
Frame = +3
Query: 57 GLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA-HTFPLDVTRVESVQEFRKYVL 233
G+G A A AREG IA I + LEK T LDVT+ + + +F V
Sbjct: 17 GIGQAAALAFAREGAKVIA---TDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVE 73
Query: 234 TVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTA 413
+ + + V++ V+ + +W + +++N+ +I AFLP++
Sbjct: 74 RL---DVLFNVAGFVHHGTVLDCEEKDW------DFSMNLNVRSMYLMIKAFLPKM---- 120
Query: 414 IETTSKPKPRIINVGS-HCGLQPLPAFAAYSASKAGLWALTR 536
++ IIN+ S ++ + YS +KA + LT+
Sbjct: 121 ---LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTK 159
>BC051291-1|AAH51291.1| 305|Homo sapiens RDH11 protein protein.
Length = 305
Score = 30.7 bits (66), Expect = 3.5
Identities = 24/77 (31%), Positives = 39/77 (50%)
Frame = +3
Query: 183 LDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLL 362
LD++ +S++ F K L K H ++NNAGVM + Y TA E + VN L
Sbjct: 86 LDLSDTKSIRAFAKGFLAEEKH-----LHVLINNAGVM-MCPYS-KTADGFEMHIGVNHL 138
Query: 363 GAMRVISAFLPEIRKTA 413
G + L +++++A
Sbjct: 139 GHFLLTHLLLEKLKESA 155
>BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 30.7 bits (66), Expect = 3.5
Identities = 40/162 (24%), Positives = 71/162 (43%), Gaps = 2/162 (1%)
Frame = +3
Query: 57 GLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA-HTFPLDVTRVESVQEFRKYVL 233
G+G A A AREG IA I + LEK T LDVT+ + + +F V
Sbjct: 17 GIGQAAALAFAREGAKVIA---TDINESKLQELEKYPGIQTRVLDVTKKKQIDQFASEVE 73
Query: 234 TVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTA 413
+ + + V++ V+ + +W + +++N+ +I AFLP++
Sbjct: 74 RL---DVLFNVAGFVHHGTVLDCEEKDW------DFSMNLNVRSMYLMIKAFLPKM---- 120
Query: 414 IETTSKPKPRIINVGS-HCGLQPLPAFAAYSASKAGLWALTR 536
++ IIN+ S ++ + YS +KA + LT+
Sbjct: 121 ---LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTK 159
>AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein.
Length = 316
Score = 30.7 bits (66), Expect = 3.5
Identities = 33/128 (25%), Positives = 58/128 (45%), Gaps = 5/128 (3%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREG---FITIAGMHKGIETEAAKALEKLCAHTF--PLDVTRVESV 209
G ++G+G A LA G +I + KG + ++ + LD++ +S+
Sbjct: 46 GANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKNSQVLVRKLDLSDTKSI 105
Query: 210 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 389
+ F + L K + H ++NNAGVM + Y TA E+ + VN LG +
Sbjct: 106 RAFAEGFLAEEK-----QLHILINNAGVM-MCPYS-KTADGFETHLGVNHLGHFLLTYLL 158
Query: 390 LPEIRKTA 413
L ++ +A
Sbjct: 159 LERLKVSA 166
>AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA
protein.
Length = 245
Score = 30.7 bits (66), Expect = 3.5
Identities = 40/162 (24%), Positives = 71/162 (43%), Gaps = 2/162 (1%)
Frame = +3
Query: 57 GLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA-HTFPLDVTRVESVQEFRKYVL 233
G+G A A AREG IA I + LEK T LDVT+ + + +F V
Sbjct: 17 GIGQAAALAFAREGAKVIA---TDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVE 73
Query: 234 TVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTA 413
+ + + V++ V+ + +W + +++N+ +I AFLP++
Sbjct: 74 RL---DVLFNVAGFVHHGTVLDCEEKDW------DFSMNLNVRSMYLMIKAFLPKM---- 120
Query: 414 IETTSKPKPRIINVGS-HCGLQPLPAFAAYSASKAGLWALTR 536
++ IIN+ S ++ + YS +KA + LT+
Sbjct: 121 ---LAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTK 159
>Z95114-1|CAI17910.1| 451|Homo sapiens apolipoprotein L, 2 protein.
Length = 451
Score = 30.3 bits (65), Expect = 4.6
Identities = 19/59 (32%), Positives = 29/59 (49%)
Frame = +3
Query: 87 AREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLTVLKDNPKYK 263
A GF+ A + + E KAL KL +H D R + Q+ R++ LK+ P+ K
Sbjct: 148 AWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKDQQHRQW---FLKEFPRLK 203
>Z82215-1|CAI22437.1| 451|Homo sapiens apolipoprotein L, 2 protein.
Length = 451
Score = 30.3 bits (65), Expect = 4.6
Identities = 19/59 (32%), Positives = 29/59 (49%)
Frame = +3
Query: 87 AREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLTVLKDNPKYK 263
A GF+ A + + E KAL KL +H D R + Q+ R++ LK+ P+ K
Sbjct: 148 AWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKDQQHRQW---FLKEFPRLK 203
>U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein.
Length = 2911
Score = 30.3 bits (65), Expect = 4.6
Identities = 14/39 (35%), Positives = 22/39 (56%)
Frame = -3
Query: 494 SEGGQRLQATMATNVDYTGLRFACSFDCSFSDLW*KCGN 378
++G R + M N+DYTG+R + +CS + CGN
Sbjct: 2189 TDGSFRCECPMGYNLDYTGVRCVDTDECSIGN---PCGN 2224
>BC004395-1|AAH04395.1| 337|Homo sapiens apolipoprotein L, 2
protein.
Length = 337
Score = 30.3 bits (65), Expect = 4.6
Identities = 19/59 (32%), Positives = 29/59 (49%)
Frame = +3
Query: 87 AREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLTVLKDNPKYK 263
A GF+ A + + E KAL KL +H D R + Q+ R++ LK+ P+ K
Sbjct: 34 AWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKDQQHRQW---FLKEFPRLK 89
>AL031426-1|CAI17902.1| 451|Homo sapiens apolipoprotein L, 2
protein.
Length = 451
Score = 30.3 bits (65), Expect = 4.6
Identities = 19/59 (32%), Positives = 29/59 (49%)
Frame = +3
Query: 87 AREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLTVLKDNPKYK 263
A GF+ A + + E KAL KL +H D R + Q+ R++ LK+ P+ K
Sbjct: 148 AWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKDQQHRQW---FLKEFPRLK 203
>AK056938-1|BAB71315.1| 337|Homo sapiens protein ( Homo sapiens
cDNA FLJ32376 fis, clone SALGL1000157, moderately
similar to APOLIPOPROTEIN L PRECURSOR. ).
Length = 337
Score = 30.3 bits (65), Expect = 4.6
Identities = 19/59 (32%), Positives = 29/59 (49%)
Frame = +3
Query: 87 AREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLTVLKDNPKYK 263
A GF+ A + + E KAL KL +H D R + Q+ R++ LK+ P+ K
Sbjct: 34 AWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKDQQHRQW---FLKEFPRLK 89
>AF324230-1|AAK11598.1| 337|Homo sapiens apolipoprotein L-II
protein.
Length = 337
Score = 30.3 bits (65), Expect = 4.6
Identities = 19/59 (32%), Positives = 29/59 (49%)
Frame = +3
Query: 87 AREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLTVLKDNPKYK 263
A GF+ A + + E KAL KL +H D R + Q+ R++ LK+ P+ K
Sbjct: 34 AWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKDQQHRQW---FLKEFPRLK 89
>AF324224-1|AAK11593.1| 337|Homo sapiens apolipoprotein L-II
protein.
Length = 337
Score = 30.3 bits (65), Expect = 4.6
Identities = 19/59 (32%), Positives = 29/59 (49%)
Frame = +3
Query: 87 AREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLTVLKDNPKYK 263
A GF+ A + + E KAL KL +H D R + Q+ R++ LK+ P+ K
Sbjct: 34 AWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKDQQHRQW---FLKEFPRLK 89
>AF324223-1|AAK11592.1| 337|Homo sapiens apolipoprotein L-II
protein.
Length = 337
Score = 30.3 bits (65), Expect = 4.6
Identities = 19/59 (32%), Positives = 29/59 (49%)
Frame = +3
Query: 87 AREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLTVLKDNPKYK 263
A GF+ A + + E KAL KL +H D R + Q+ R++ LK+ P+ K
Sbjct: 34 AWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKDQQHRQW---FLKEFPRLK 89
>AF305429-1|AAL09359.1| 337|Homo sapiens apolipoprotein L2 protein.
Length = 337
Score = 30.3 bits (65), Expect = 4.6
Identities = 19/59 (32%), Positives = 29/59 (49%)
Frame = +3
Query: 87 AREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLTVLKDNPKYK 263
A GF+ A + + E KAL KL +H D R + Q+ R++ LK+ P+ K
Sbjct: 34 AWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKDQQHRQW---FLKEFPRLK 89
>AF305225-1|AAK20211.1| 337|Homo sapiens apolipoprotein L2 protein.
Length = 337
Score = 30.3 bits (65), Expect = 4.6
Identities = 19/59 (32%), Positives = 29/59 (49%)
Frame = +3
Query: 87 AREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLTVLKDNPKYK 263
A GF+ A + + E KAL KL +H D R + Q+ R++ LK+ P+ K
Sbjct: 34 AWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKDQQHRQW---FLKEFPRLK 89
>AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital
contractural arachnodactyly) variant protein.
Length = 1976
Score = 30.3 bits (65), Expect = 4.6
Identities = 14/39 (35%), Positives = 22/39 (56%)
Frame = -3
Query: 494 SEGGQRLQATMATNVDYTGLRFACSFDCSFSDLW*KCGN 378
++G R + M N+DYTG+R + +CS + CGN
Sbjct: 1254 TDGSFRCECPMGYNLDYTGVRCVDTDECSIGN---PCGN 1289
>AB208990-1|BAD92227.1| 415|Homo sapiens apolipoprotein L2 variant
protein.
Length = 415
Score = 30.3 bits (65), Expect = 4.6
Identities = 19/59 (32%), Positives = 29/59 (49%)
Frame = +3
Query: 87 AREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEFRKYVLTVLKDNPKYK 263
A GF+ A + + E KAL KL +H D R + Q+ R++ LK+ P+ K
Sbjct: 112 AWNGFVAAAELPRDEADELRKALNKLASHMVMKDKNRHDKDQQHRQW---FLKEFPRLK 167
>CR381696-1|CAI95409.1| 245|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 245
Score = 29.9 bits (64), Expect = 6.1
Identities = 26/103 (25%), Positives = 45/103 (43%), Gaps = 2/103 (1%)
Frame = +3
Query: 108 IAGMHKGIETEAAKALEKLCAHTFPLDVTRVE--SVQEFRKYVLTVLKDNPKYKFHAVVN 281
+ G GI AK L +L H ++ + S+ R++V K H ++N
Sbjct: 48 VTGGTDGIGYSTAKHLARLGMHVIIVEFLYCDLASMTSIRQFVQKFKMK--KIPLHVLIN 105
Query: 282 NAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKT 410
NAGVM V + + T E +N LG + + L ++++
Sbjct: 106 NAGVMMVPQRK--TRDGFEEHFGLNYLGHFLLTNLLLDTLKES 146
>BX649443-1|CAI95430.1| 245|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 245
Score = 29.9 bits (64), Expect = 6.1
Identities = 26/103 (25%), Positives = 45/103 (43%), Gaps = 2/103 (1%)
Frame = +3
Query: 108 IAGMHKGIETEAAKALEKLCAHTFPLDVTRVE--SVQEFRKYVLTVLKDNPKYKFHAVVN 281
+ G GI AK L +L H ++ + S+ R++V K H ++N
Sbjct: 48 VTGGTDGIGYSTAKHLARLGMHVIIVEFLYCDLASMTSIRQFVQKFKMK--KIPLHVLIN 105
Query: 282 NAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKT 410
NAGVM V + + T E +N LG + + L ++++
Sbjct: 106 NAGVMMVPQRK--TRDGFEEHFGLNYLGHFLLTNLLLDTLKES 146
>BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 29.9 bits (64), Expect = 6.1
Identities = 41/170 (24%), Positives = 61/170 (35%), Gaps = 4/170 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCA--HTFPLDVTRVESVQ 212
G G+G +A A G I + G + E + + ++ H F DV E V
Sbjct: 45 GGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVY 104
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
+ K V + D +VNNA V+ + H+N LG AFL
Sbjct: 105 QTAKAVREKVGD-----ITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFL 159
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
P + + I+ + S L +P Y SKA +A L
Sbjct: 160 PRMLEL-------QNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESL 202
>AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 29.9 bits (64), Expect = 6.1
Identities = 41/170 (24%), Positives = 61/170 (35%), Gaps = 4/170 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCA--HTFPLDVTRVESVQ 212
G G+G +A A G I + G + E + + ++ H F DV E V
Sbjct: 45 GGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVY 104
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
+ K V + D +VNNA V+ + H+N LG AFL
Sbjct: 105 QTAKAVREKVGD-----ITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFL 159
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
P + + I+ + S L +P Y SKA +A L
Sbjct: 160 PRMLEL-------QNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESL 202
>AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 29.9 bits (64), Expect = 6.1
Identities = 41/170 (24%), Positives = 61/170 (35%), Gaps = 4/170 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCA--HTFPLDVTRVESVQ 212
G G+G +A A G I + G + E + + ++ H F DV E V
Sbjct: 45 GGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVY 104
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
+ K V + D +VNNA V+ + H+N LG AFL
Sbjct: 105 QTAKAVREKVGD-----ITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFL 159
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
P + + I+ + S L +P Y SKA +A L
Sbjct: 160 PRMLEL-------QNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESL 202
>AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 variant protein.
Length = 302
Score = 29.9 bits (64), Expect = 6.1
Identities = 41/170 (24%), Positives = 61/170 (35%), Gaps = 4/170 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCA--HTFPLDVTRVESVQ 212
G G+G +A A G I + G + E + + ++ H F DV E V
Sbjct: 45 GGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVY 104
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
+ K V + D +VNNA V+ + H+N LG AFL
Sbjct: 105 QTAKAVREKVGD-----ITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFL 159
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
P + + I+ + S L +P Y SKA +A L
Sbjct: 160 PRMLEL-------QNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESL 202
>AF179237-1|AAD55402.1| 302|Homo sapiens short-chain
dehydrogenase/reductase 1 protein.
Length = 302
Score = 29.9 bits (64), Expect = 6.1
Identities = 41/170 (24%), Positives = 61/170 (35%), Gaps = 4/170 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCA--HTFPLDVTRVESVQ 212
G G+G +A A G I + G + E + + ++ H F DV E V
Sbjct: 45 GGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVY 104
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
+ K V + D +VNNA V+ + H+N LG AFL
Sbjct: 105 QTAKAVREKVGD-----ITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFL 159
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
P + + I+ + S L +P Y SKA +A L
Sbjct: 160 PRMLEL-------QNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESL 202
>AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR1 protein.
Length = 302
Score = 29.9 bits (64), Expect = 6.1
Identities = 41/170 (24%), Positives = 61/170 (35%), Gaps = 4/170 (2%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCA--HTFPLDVTRVESVQ 212
G G+G +A A G I + G + E + + ++ H F DV E V
Sbjct: 45 GGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVY 104
Query: 213 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 392
+ K V + D +VNNA V+ + H+N LG AFL
Sbjct: 105 QTAKAVREKVGD-----ITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFL 159
Query: 393 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKAGLWALTRCL 542
P + + I+ + S L +P Y SKA +A L
Sbjct: 160 PRMLEL-------QNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESL 202
>M76231-1|AAA60314.1| 261|Homo sapiens sepiapterin reductase
protein.
Length = 261
Score = 29.5 bits (63), Expect = 8.0
Identities = 11/24 (45%), Positives = 15/24 (62%)
Frame = +3
Query: 444 IINVGSHCGLQPLPAFAAYSASKA 515
++N+ S C LQP +A Y A KA
Sbjct: 152 VVNISSLCALQPFKGWALYCAGKA 175
>BC017310-1|AAH17310.1| 261|Homo sapiens sepiapterin reductase
(7,8-dihydrobiopterin:NADP+ oxidoreductase) protein.
Length = 261
Score = 29.5 bits (63), Expect = 8.0
Identities = 11/24 (45%), Positives = 15/24 (62%)
Frame = +3
Query: 444 IINVGSHCGLQPLPAFAAYSASKA 515
++N+ S C LQP +A Y A KA
Sbjct: 152 VVNISSLCALQPFKGWALYCAGKA 175
>AK222942-1|BAD96662.1| 261|Homo sapiens sepiapterin reductase
(7,8-dihydrobiopterin:NADP+ oxidoreductase) variant
protein.
Length = 261
Score = 29.5 bits (63), Expect = 8.0
Identities = 11/24 (45%), Positives = 15/24 (62%)
Frame = +3
Query: 444 IINVGSHCGLQPLPAFAAYSASKA 515
++N+ S C LQP +A Y A KA
Sbjct: 152 VVNISSLCALQPFKGWALYCAGKA 175
>AC092630-1|AAY15035.1| 198|Homo sapiens unknown protein.
Length = 198
Score = 29.5 bits (63), Expect = 8.0
Identities = 11/24 (45%), Positives = 15/24 (62%)
Frame = +3
Query: 444 IINVGSHCGLQPLPAFAAYSASKA 515
++N+ S C LQP +A Y A KA
Sbjct: 152 VVNISSLCALQPFKGWALYCAGKA 175
>AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 166
Score = 29.5 bits (63), Expect = 8.0
Identities = 14/36 (38%), Positives = 20/36 (55%)
Frame = +3
Query: 45 GCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKA 152
G SG+G+A+A RLAR+G + K + A A
Sbjct: 60 GSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMA 95
>AB017547-1|BAA34534.1| 198|Homo sapiens sepiapterin reductase
protein.
Length = 198
Score = 29.5 bits (63), Expect = 8.0
Identities = 11/24 (45%), Positives = 15/24 (62%)
Frame = +3
Query: 444 IINVGSHCGLQPLPAFAAYSASKA 515
++N+ S C LQP +A Y A KA
Sbjct: 152 VVNISSLCALQPFKGWALYCAGKA 175
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 77,584,451
Number of Sequences: 237096
Number of extensions: 1589169
Number of successful extensions: 7723
Number of sequences better than 10.0: 175
Number of HSP's better than 10.0 without gapping: 7491
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7665
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5364536570
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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