Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fprWP02_F_F12
(652 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X91349-1|CAA62690.1| 858|Homo sapiens de-ubiquitinase protein. 111 2e-24
U47927-1|AAC50465.1| 858|Homo sapiens isopeptidase T protein. 111 2e-24
U47924-8|AAB51314.1| 835|Homo sapiens isopeptidase T protein. 111 2e-24
U47924-7|AAB51315.1| 858|Homo sapiens isopeptidase T protein. 111 2e-24
U35116-1|AAA78934.1| 835|Homo sapiens ubiquitin isopeptidase T ... 111 2e-24
BC005139-1|AAH05139.1| 858|Homo sapiens USP5 protein protein. 111 2e-24
BC004889-1|AAH04889.1| 835|Homo sapiens ubiquitin specific pept... 111 2e-24
U75362-1|AAC63405.1| 863|Homo sapiens isopeptidase T-3 protein. 77 5e-14
BC016146-1|AAH16146.1| 863|Homo sapiens ubiquitin specific pept... 77 7e-14
BC094773-1|AAH94773.1| 1009|Homo sapiens mannosidase, alpha, cla... 31 3.6
BC036836-1|AAH36836.1| 358|Homo sapiens MAN2B2 protein protein. 31 3.6
BC033307-1|AAH33307.1| 1009|Homo sapiens mannosidase, alpha, cla... 31 3.6
AL833071-1|CAD89971.1| 1009|Homo sapiens hypothetical protein pr... 31 3.6
AY078498-1|AAL85487.2| 1507|Homo sapiens zinc finger 298 protein. 30 6.2
AP001745-1|BAA95527.1| 847|Homo sapiens ZNF298 protein. 30 6.2
AF276513-1|AAF78093.1| 951|Homo sapiens PR-domain zinc finger p... 30 6.2
>X91349-1|CAA62690.1| 858|Homo sapiens de-ubiquitinase protein.
Length = 858
Score = 111 bits (268), Expect = 2e-24
Identities = 65/148 (43%), Positives = 90/148 (60%), Gaps = 7/148 (4%)
Frame = +2
Query: 230 GFGRNYVEQYFQKTGNAVFLHIRREKQPIPEPEQTGDG--PEKKITKLAIGVEGGFDPEC 403
GFG+ YVE++F KTG V+LH+RR ++P E TG G P KK T+LAIGVEGGFD
Sbjct: 52 GFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFD--L 109
Query: 404 GKPKFTYTDHYSVVVLPGFHTFPWPD-PNLPEPVK----KSVQAVIDAESPFKIAELAAL 568
+ KF + +V+LP + LP+ V+ +V+A++ A+S + E+ A
Sbjct: 110 SEEKFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQA- 168
Query: 569 QGTWDGEKREVSVHSVNLKQLDNGIRIP 652
WDGE R+VS H+ +LKQLDN RIP
Sbjct: 169 ---WDGEVRQVSKHAFSLKQLDNPARIP 193
Score = 49.2 bits (112), Expect = 1e-05
Identities = 23/43 (53%), Positives = 29/43 (67%)
Frame = +1
Query: 100 LTSHLSKIKLPGPHQLVYKDECVYSFDNPESETGLYVSLVSFL 228
L S L I++P V+KDEC +SFD PESE GLYV + +FL
Sbjct: 9 LLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYVCMNTFL 51
>U47927-1|AAC50465.1| 858|Homo sapiens isopeptidase T protein.
Length = 858
Score = 111 bits (268), Expect = 2e-24
Identities = 65/148 (43%), Positives = 90/148 (60%), Gaps = 7/148 (4%)
Frame = +2
Query: 230 GFGRNYVEQYFQKTGNAVFLHIRREKQPIPEPEQTGDG--PEKKITKLAIGVEGGFDPEC 403
GFG+ YVE++F KTG V+LH+RR ++P E TG G P KK T+LAIGVEGGFD
Sbjct: 52 GFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFD--L 109
Query: 404 GKPKFTYTDHYSVVVLPGFHTFPWPD-PNLPEPVK----KSVQAVIDAESPFKIAELAAL 568
+ KF + +V+LP + LP+ V+ +V+A++ A+S + E+ A
Sbjct: 110 SEEKFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQA- 168
Query: 569 QGTWDGEKREVSVHSVNLKQLDNGIRIP 652
WDGE R+VS H+ +LKQLDN RIP
Sbjct: 169 ---WDGEVRQVSKHAFSLKQLDNPARIP 193
Score = 50.0 bits (114), Expect = 7e-06
Identities = 26/51 (50%), Positives = 33/51 (64%), Gaps = 2/51 (3%)
Frame = +1
Query: 82 MASLS--LLTSHLSKIKLPGPHQLVYKDECVYSFDNPESETGLYVSLVSFL 228
MA LS L S L I++P V+KDEC +SFD PESE GLY+ + +FL
Sbjct: 1 MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFL 51
>U47924-8|AAB51314.1| 835|Homo sapiens isopeptidase T protein.
Length = 835
Score = 111 bits (268), Expect = 2e-24
Identities = 65/148 (43%), Positives = 90/148 (60%), Gaps = 7/148 (4%)
Frame = +2
Query: 230 GFGRNYVEQYFQKTGNAVFLHIRREKQPIPEPEQTGDG--PEKKITKLAIGVEGGFDPEC 403
GFG+ YVE++F KTG V+LH+RR ++P E TG G P KK T+LAIGVEGGFD
Sbjct: 52 GFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFD--L 109
Query: 404 GKPKFTYTDHYSVVVLPGFHTFPWPD-PNLPEPVK----KSVQAVIDAESPFKIAELAAL 568
+ KF + +V+LP + LP+ V+ +V+A++ A+S + E+ A
Sbjct: 110 SEEKFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQA- 168
Query: 569 QGTWDGEKREVSVHSVNLKQLDNGIRIP 652
WDGE R+VS H+ +LKQLDN RIP
Sbjct: 169 ---WDGEVRQVSKHAFSLKQLDNPARIP 193
Score = 50.0 bits (114), Expect = 7e-06
Identities = 26/51 (50%), Positives = 33/51 (64%), Gaps = 2/51 (3%)
Frame = +1
Query: 82 MASLS--LLTSHLSKIKLPGPHQLVYKDECVYSFDNPESETGLYVSLVSFL 228
MA LS L S L I++P V+KDEC +SFD PESE GLY+ + +FL
Sbjct: 1 MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFL 51
>U47924-7|AAB51315.1| 858|Homo sapiens isopeptidase T protein.
Length = 858
Score = 111 bits (268), Expect = 2e-24
Identities = 65/148 (43%), Positives = 90/148 (60%), Gaps = 7/148 (4%)
Frame = +2
Query: 230 GFGRNYVEQYFQKTGNAVFLHIRREKQPIPEPEQTGDG--PEKKITKLAIGVEGGFDPEC 403
GFG+ YVE++F KTG V+LH+RR ++P E TG G P KK T+LAIGVEGGFD
Sbjct: 52 GFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFD--L 109
Query: 404 GKPKFTYTDHYSVVVLPGFHTFPWPD-PNLPEPVK----KSVQAVIDAESPFKIAELAAL 568
+ KF + +V+LP + LP+ V+ +V+A++ A+S + E+ A
Sbjct: 110 SEEKFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQA- 168
Query: 569 QGTWDGEKREVSVHSVNLKQLDNGIRIP 652
WDGE R+VS H+ +LKQLDN RIP
Sbjct: 169 ---WDGEVRQVSKHAFSLKQLDNPARIP 193
Score = 50.0 bits (114), Expect = 7e-06
Identities = 26/51 (50%), Positives = 33/51 (64%), Gaps = 2/51 (3%)
Frame = +1
Query: 82 MASLS--LLTSHLSKIKLPGPHQLVYKDECVYSFDNPESETGLYVSLVSFL 228
MA LS L S L I++P V+KDEC +SFD PESE GLY+ + +FL
Sbjct: 1 MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFL 51
>U35116-1|AAA78934.1| 835|Homo sapiens ubiquitin isopeptidase T
protein.
Length = 835
Score = 111 bits (268), Expect = 2e-24
Identities = 65/148 (43%), Positives = 90/148 (60%), Gaps = 7/148 (4%)
Frame = +2
Query: 230 GFGRNYVEQYFQKTGNAVFLHIRREKQPIPEPEQTGDG--PEKKITKLAIGVEGGFDPEC 403
GFG+ YVE++F KTG V+LH+RR ++P E TG G P KK T+LAIGVEGGFD
Sbjct: 52 GFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFD--L 109
Query: 404 GKPKFTYTDHYSVVVLPGFHTFPWPD-PNLPEPVK----KSVQAVIDAESPFKIAELAAL 568
+ KF + +V+LP + LP+ V+ +V+A++ A+S + E+ A
Sbjct: 110 SEEKFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQA- 168
Query: 569 QGTWDGEKREVSVHSVNLKQLDNGIRIP 652
WDGE R+VS H+ +LKQLDN RIP
Sbjct: 169 ---WDGEVRQVSKHAFSLKQLDNPARIP 193
Score = 50.0 bits (114), Expect = 7e-06
Identities = 26/51 (50%), Positives = 33/51 (64%), Gaps = 2/51 (3%)
Frame = +1
Query: 82 MASLS--LLTSHLSKIKLPGPHQLVYKDECVYSFDNPESETGLYVSLVSFL 228
MA LS L S L I++P V+KDEC +SFD PESE GLY+ + +FL
Sbjct: 1 MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFL 51
>BC005139-1|AAH05139.1| 858|Homo sapiens USP5 protein protein.
Length = 858
Score = 111 bits (268), Expect = 2e-24
Identities = 65/148 (43%), Positives = 90/148 (60%), Gaps = 7/148 (4%)
Frame = +2
Query: 230 GFGRNYVEQYFQKTGNAVFLHIRREKQPIPEPEQTGDG--PEKKITKLAIGVEGGFDPEC 403
GFG+ YVE++F KTG V+LH+RR ++P E TG G P KK T+LAIGVEGGFD
Sbjct: 52 GFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFD--L 109
Query: 404 GKPKFTYTDHYSVVVLPGFHTFPWPD-PNLPEPVK----KSVQAVIDAESPFKIAELAAL 568
+ KF + +V+LP + LP+ V+ +V+A++ A+S + E+ A
Sbjct: 110 SEEKFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQA- 168
Query: 569 QGTWDGEKREVSVHSVNLKQLDNGIRIP 652
WDGE R+VS H+ +LKQLDN RIP
Sbjct: 169 ---WDGEVRQVSKHAFSLKQLDNPARIP 193
Score = 50.0 bits (114), Expect = 7e-06
Identities = 26/51 (50%), Positives = 33/51 (64%), Gaps = 2/51 (3%)
Frame = +1
Query: 82 MASLS--LLTSHLSKIKLPGPHQLVYKDECVYSFDNPESETGLYVSLVSFL 228
MA LS L S L I++P V+KDEC +SFD PESE GLY+ + +FL
Sbjct: 1 MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFL 51
>BC004889-1|AAH04889.1| 835|Homo sapiens ubiquitin specific
peptidase 5 (isopeptidase T) protein.
Length = 835
Score = 111 bits (268), Expect = 2e-24
Identities = 65/148 (43%), Positives = 90/148 (60%), Gaps = 7/148 (4%)
Frame = +2
Query: 230 GFGRNYVEQYFQKTGNAVFLHIRREKQPIPEPEQTGDG--PEKKITKLAIGVEGGFDPEC 403
GFG+ YVE++F KTG V+LH+RR ++P E TG G P KK T+LAIGVEGGFD
Sbjct: 52 GFGKQYVERHFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFD--L 109
Query: 404 GKPKFTYTDHYSVVVLPGFHTFPWPD-PNLPEPVK----KSVQAVIDAESPFKIAELAAL 568
+ KF + +V+LP + LP+ V+ +V+A++ A+S + E+ A
Sbjct: 110 SEEKFELDEDVKIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQA- 168
Query: 569 QGTWDGEKREVSVHSVNLKQLDNGIRIP 652
WDGE R+VS H+ +LKQLDN RIP
Sbjct: 169 ---WDGEVRQVSKHAFSLKQLDNPARIP 193
Score = 50.0 bits (114), Expect = 7e-06
Identities = 26/51 (50%), Positives = 33/51 (64%), Gaps = 2/51 (3%)
Frame = +1
Query: 82 MASLS--LLTSHLSKIKLPGPHQLVYKDECVYSFDNPESETGLYVSLVSFL 228
MA LS L S L I++P V+KDEC +SFD PESE GLY+ + +FL
Sbjct: 1 MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFL 51
>U75362-1|AAC63405.1| 863|Homo sapiens isopeptidase T-3 protein.
Length = 863
Score = 77.0 bits (181), Expect = 5e-14
Identities = 43/141 (30%), Positives = 78/141 (55%), Gaps = 1/141 (0%)
Frame = +2
Query: 233 FGRNYVEQYFQKTGNAVFLHIRREKQPIPEPEQTGDGPEKKITKLAIGVEGGFDPECGKP 412
FGR +VE++F+KTG +V++H++R + G P+++ +K+ + ++ D +
Sbjct: 72 FGREHVERHFRKTGQSVYMHLKRHAREKVRGASGGALPKRRNSKIFLDLD--TDDDLNSD 129
Query: 413 KFTYTDHYSVVVLPGFHTFPWPD-PNLPEPVKKSVQAVIDAESPFKIAELAALQGTWDGE 589
+ Y D +V+ P + P+ LP V + AV+ ++SP++ + TW+ E
Sbjct: 130 DYEYEDEAKLVIFPDHYEIALPNIEELPALVTIACDAVLSSKSPYRKQD----PDTWENE 185
Query: 590 KREVSVHSVNLKQLDNGIRIP 652
VS ++ NL QLDNG+RIP
Sbjct: 186 -LPVSKYANNLTQLDNGVRIP 205
Score = 50.0 bits (114), Expect = 7e-06
Identities = 21/44 (47%), Positives = 30/44 (68%)
Frame = +1
Query: 97 LLTSHLSKIKLPGPHQLVYKDECVYSFDNPESETGLYVSLVSFL 228
LL H+ I++P VYK+EC +S+D+P SE GLYV + +FL
Sbjct: 27 LLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEGGLYVCMNTFL 70
>BC016146-1|AAH16146.1| 863|Homo sapiens ubiquitin specific
peptidase 13 (isopeptidase T-3) protein.
Length = 863
Score = 76.6 bits (180), Expect = 7e-14
Identities = 43/141 (30%), Positives = 78/141 (55%), Gaps = 1/141 (0%)
Frame = +2
Query: 233 FGRNYVEQYFQKTGNAVFLHIRREKQPIPEPEQTGDGPEKKITKLAIGVEGGFDPECGKP 412
FGR +VE++F+KTG +V++H++R + G P+++ +K+ + ++ D +
Sbjct: 72 FGREHVERHFRKTGQSVYMHLKRHVREKVRGASGGALPKRRNSKIFLDLD--TDDDLNSD 129
Query: 413 KFTYTDHYSVVVLPGFHTFPWPD-PNLPEPVKKSVQAVIDAESPFKIAELAALQGTWDGE 589
+ Y D +V+ P + P+ LP V + AV+ ++SP++ + TW+ E
Sbjct: 130 DYEYEDEAKLVIFPDHYEIALPNIEELPALVTIACDAVLSSKSPYRKQD----PDTWENE 185
Query: 590 KREVSVHSVNLKQLDNGIRIP 652
VS ++ NL QLDNG+RIP
Sbjct: 186 -LPVSKYANNLTQLDNGVRIP 205
Score = 50.0 bits (114), Expect = 7e-06
Identities = 21/44 (47%), Positives = 30/44 (68%)
Frame = +1
Query: 97 LLTSHLSKIKLPGPHQLVYKDECVYSFDNPESETGLYVSLVSFL 228
LL H+ I++P VYK+EC +S+D+P SE GLYV + +FL
Sbjct: 27 LLVPHMPTIRVPRSGDRVYKNECAFSYDSPNSEGGLYVCMNTFL 70
>BC094773-1|AAH94773.1| 1009|Homo sapiens mannosidase, alpha, class
2B, member 2 protein.
Length = 1009
Score = 31.1 bits (67), Expect = 3.6
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Frame = +2
Query: 443 VVLPGFHTFP-WPDPNLPEPVKKSVQAVIDAESPFKIAELAALQGTWD 583
V+L +H + DP L +PV +++AV+ A E +L GTWD
Sbjct: 913 VLLRLYHLYEVGEDPVLSQPVTVNLEAVLQALGSVVAVEERSLTGTWD 960
>BC036836-1|AAH36836.1| 358|Homo sapiens MAN2B2 protein protein.
Length = 358
Score = 31.1 bits (67), Expect = 3.6
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Frame = +2
Query: 443 VVLPGFHTFP-WPDPNLPEPVKKSVQAVIDAESPFKIAELAALQGTWD 583
V+L +H + DP L +PV +++AV+ A E +L GTWD
Sbjct: 262 VLLRLYHLYEVGEDPVLSQPVTVNLEAVLQALGSVVAVEERSLTGTWD 309
>BC033307-1|AAH33307.1| 1009|Homo sapiens mannosidase, alpha, class
2B, member 2 protein.
Length = 1009
Score = 31.1 bits (67), Expect = 3.6
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Frame = +2
Query: 443 VVLPGFHTFP-WPDPNLPEPVKKSVQAVIDAESPFKIAELAALQGTWD 583
V+L +H + DP L +PV +++AV+ A E +L GTWD
Sbjct: 913 VLLRLYHLYEVGEDPVLSQPVTVNLEAVLQALGSVVAVEERSLTGTWD 960
>AL833071-1|CAD89971.1| 1009|Homo sapiens hypothetical protein
protein.
Length = 1009
Score = 31.1 bits (67), Expect = 3.6
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Frame = +2
Query: 443 VVLPGFHTFP-WPDPNLPEPVKKSVQAVIDAESPFKIAELAALQGTWD 583
V+L +H + DP L +PV +++AV+ A E +L GTWD
Sbjct: 913 VLLRLYHLYEVGEDPVLSQPVTVNLEAVLQALGSVVAVEERSLTGTWD 960
>AY078498-1|AAL85487.2| 1507|Homo sapiens zinc finger 298 protein.
Length = 1507
Score = 30.3 bits (65), Expect = 6.2
Identities = 13/37 (35%), Positives = 21/37 (56%)
Frame = +2
Query: 536 SPFKIAELAALQGTWDGEKREVSVHSVNLKQLDNGIR 646
SPFK+ ++ ++G W+ R S+H+ L GIR
Sbjct: 253 SPFKLLGMSGVEGVWNQHSRSASMHTF-LNHSATGIR 288
>AP001745-1|BAA95527.1| 847|Homo sapiens ZNF298 protein.
Length = 847
Score = 30.3 bits (65), Expect = 6.2
Identities = 13/37 (35%), Positives = 21/37 (56%)
Frame = +2
Query: 536 SPFKIAELAALQGTWDGEKREVSVHSVNLKQLDNGIR 646
SPFK+ ++ ++G W+ R S+H+ L GIR
Sbjct: 253 SPFKLLGMSGVEGVWNQHSRSASMHTF-LNHSATGIR 288
>AF276513-1|AAF78093.1| 951|Homo sapiens PR-domain zinc finger
protein 15 protein.
Length = 951
Score = 30.3 bits (65), Expect = 6.2
Identities = 13/37 (35%), Positives = 21/37 (56%)
Frame = +2
Query: 536 SPFKIAELAALQGTWDGEKREVSVHSVNLKQLDNGIR 646
SPFK+ ++ ++G W+ R S+H+ L GIR
Sbjct: 253 SPFKLLGMSGVEGVWNQHSRSASMHTF-LNHSATGIR 288
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 103,431,559
Number of Sequences: 237096
Number of extensions: 2543911
Number of successful extensions: 6373
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 6044
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6357
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7253890590
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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