Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fprWP02_F_E14
(654 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 41 0.004
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 41 0.004
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 41 0.004
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 41 0.004
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 41 0.004
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 36 0.17
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 36 0.17
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 36 0.17
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 36 0.17
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 36 0.17
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 36 0.17
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 36 0.17
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 36 0.17
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 36 0.17
S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 34 0.39
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 34 0.39
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 34 0.39
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 34 0.39
AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 34 0.39
AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 34 0.39
AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 34 0.39
AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 34 0.39
>X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase
protein.
Length = 530
Score = 40.7 bits (91), Expect = 0.004
Identities = 33/150 (22%), Positives = 61/150 (40%), Gaps = 6/150 (4%)
Frame = +3
Query: 222 LHKYLPLIVIGVVAFNERFNSFALSEQDPESRSSKTIAAAFGSNSGVMKLDKGFLWKMFS 401
L Y L I + F +R S + ++I F ++ L K W
Sbjct: 207 LFYYFALEAICYILFEKRIGCLQRSIPEDTVTFVRSIGLMFQNSLYATFLPK---WTRPV 263
Query: 402 TPLYKKLVNSQIYLXKISTXILIXKINLFESD------DSKNDKSLLKTFLQQPQLDHKD 563
P +K+ ++ + ++ K+ E+ D L L QL ++
Sbjct: 264 LPFWKRYLDGWNAIFSFGKKLIDEKLEDMEAQLQAAGPDGIQVSGYLHFLLASGQLSPRE 323
Query: 564 IMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
MG + ++LMA +DTT+ T ++ LYH+ ++
Sbjct: 324 AMGSLPELLMAGVDTTSNTLTWALYHLSKD 353
>M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase
protein.
Length = 531
Score = 40.7 bits (91), Expect = 0.004
Identities = 33/150 (22%), Positives = 61/150 (40%), Gaps = 6/150 (4%)
Frame = +3
Query: 222 LHKYLPLIVIGVVAFNERFNSFALSEQDPESRSSKTIAAAFGSNSGVMKLDKGFLWKMFS 401
L Y L I + F +R S + ++I F ++ L K W
Sbjct: 208 LFYYFALEAICYILFEKRIGCLQRSIPEDTVTFVRSIGLMFQNSLYATFLPK---WTRPV 264
Query: 402 TPLYKKLVNSQIYLXKISTXILIXKINLFESD------DSKNDKSLLKTFLQQPQLDHKD 563
P +K+ ++ + ++ K+ E+ D L L QL ++
Sbjct: 265 LPFWKRYLDGWNAIFSFGKKLIDEKLEDMEAQLQAAGPDGIQVSGYLHFLLASGQLSPRE 324
Query: 564 IMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
MG + ++LMA +DTT+ T ++ LYH+ ++
Sbjct: 325 AMGSLPELLMAGVDTTSNTLTWALYHLSKD 354
>BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 40.7 bits (91), Expect = 0.004
Identities = 33/150 (22%), Positives = 61/150 (40%), Gaps = 6/150 (4%)
Frame = +3
Query: 222 LHKYLPLIVIGVVAFNERFNSFALSEQDPESRSSKTIAAAFGSNSGVMKLDKGFLWKMFS 401
L Y L I + F +R S + ++I F ++ L K W
Sbjct: 208 LFYYFALEAICYILFEKRIGCLQRSIPEDTVTFVRSIGLMFQNSLYATFLPK---WTRPV 264
Query: 402 TPLYKKLVNSQIYLXKISTXILIXKINLFESD------DSKNDKSLLKTFLQQPQLDHKD 563
P +K+ ++ + ++ K+ E+ D L L QL ++
Sbjct: 265 LPFWKRYLDGWNAIFSFGKKLIDEKLEDMEAQLQAAGPDGIQVSGYLHFLLASGQLSPRE 324
Query: 564 IMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
MG + ++LMA +DTT+ T ++ LYH+ ++
Sbjct: 325 AMGSLPELLMAGVDTTSNTLTWALYHLSKD 354
>BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 40.7 bits (91), Expect = 0.004
Identities = 33/150 (22%), Positives = 61/150 (40%), Gaps = 6/150 (4%)
Frame = +3
Query: 222 LHKYLPLIVIGVVAFNERFNSFALSEQDPESRSSKTIAAAFGSNSGVMKLDKGFLWKMFS 401
L Y L I + F +R S + ++I F ++ L K W
Sbjct: 208 LFYYFALEAICYILFEKRIGCLQRSIPEDTVTFVRSIGLMFQNSLYATFLPK---WTRPV 264
Query: 402 TPLYKKLVNSQIYLXKISTXILIXKINLFESD------DSKNDKSLLKTFLQQPQLDHKD 563
P +K+ ++ + ++ K+ E+ D L L QL ++
Sbjct: 265 LPFWKRYLDGWNAIFSFGKKLIDEKLEDMEAQLQAAGPDGIQVSGYLHFLLASGQLSPRE 324
Query: 564 IMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
MG + ++LMA +DTT+ T ++ LYH+ ++
Sbjct: 325 AMGSLPELLMAGVDTTSNTLTWALYHLSKD 354
>AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase
protein.
Length = 531
Score = 40.7 bits (91), Expect = 0.004
Identities = 33/150 (22%), Positives = 61/150 (40%), Gaps = 6/150 (4%)
Frame = +3
Query: 222 LHKYLPLIVIGVVAFNERFNSFALSEQDPESRSSKTIAAAFGSNSGVMKLDKGFLWKMFS 401
L Y L I + F +R S + ++I F ++ L K W
Sbjct: 208 LFYYFALEAICYILFEKRIGCLQRSIPEDTVTFVRSIGLMFQNSLYATFLPK---WTRPV 264
Query: 402 TPLYKKLVNSQIYLXKISTXILIXKINLFESD------DSKNDKSLLKTFLQQPQLDHKD 563
P +K+ ++ + ++ K+ E+ D L L QL ++
Sbjct: 265 LPFWKRYLDGWNAIFSFGKKLIDEKLEDMEAQLQAAGPDGIQVSGYLHFLLASGQLSPRE 324
Query: 564 IMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
MG + ++LMA +DTT+ T ++ LYH+ ++
Sbjct: 325 AMGSLPELLMAGVDTTSNTLTWALYHLSKD 354
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 35.5 bits (78), Expect = 0.17
Identities = 15/44 (34%), Positives = 28/44 (63%)
Frame = +3
Query: 522 LKTFLQQPQLDHKDIMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
L FL + +L + I+G + ++L+A +DT + T S+ LY + R+
Sbjct: 293 LTHFLFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRH 336
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 35.5 bits (78), Expect = 0.17
Identities = 15/44 (34%), Positives = 28/44 (63%)
Frame = +3
Query: 522 LKTFLQQPQLDHKDIMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
L FL + +L + I+G + ++L+A +DT + T S+ LY + R+
Sbjct: 293 LTHFLFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRH 336
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 35.5 bits (78), Expect = 0.17
Identities = 15/44 (34%), Positives = 28/44 (63%)
Frame = +3
Query: 522 LKTFLQQPQLDHKDIMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
L FL + +L + I+G + ++L+A +DT + T S+ LY + R+
Sbjct: 293 LTHFLFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRH 336
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 35.5 bits (78), Expect = 0.17
Identities = 15/44 (34%), Positives = 28/44 (63%)
Frame = +3
Query: 522 LKTFLQQPQLDHKDIMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
L FL + +L + I+G + ++L+A +DT + T S+ LY + R+
Sbjct: 293 LTHFLFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRH 336
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 35.5 bits (78), Expect = 0.17
Identities = 15/44 (34%), Positives = 28/44 (63%)
Frame = +3
Query: 522 LKTFLQQPQLDHKDIMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
L FL + +L + I+G + ++L+A +DT + T S+ LY + R+
Sbjct: 293 LTHFLFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRH 336
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 35.5 bits (78), Expect = 0.17
Identities = 15/44 (34%), Positives = 28/44 (63%)
Frame = +3
Query: 522 LKTFLQQPQLDHKDIMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
L FL + +L + I+G + ++L+A +DT + T S+ LY + R+
Sbjct: 293 LTHFLFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRH 336
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 35.5 bits (78), Expect = 0.17
Identities = 15/44 (34%), Positives = 28/44 (63%)
Frame = +3
Query: 522 LKTFLQQPQLDHKDIMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
L FL + +L + I+G + ++L+A +DT + T S+ LY + R+
Sbjct: 293 LTHFLFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRH 336
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 35.5 bits (78), Expect = 0.17
Identities = 15/44 (34%), Positives = 28/44 (63%)
Frame = +3
Query: 522 LKTFLQQPQLDHKDIMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
L FL + +L + I+G + ++L+A +DT + T S+ LY + R+
Sbjct: 293 LTHFLFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRH 336
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 35.5 bits (78), Expect = 0.17
Identities = 15/44 (34%), Positives = 28/44 (63%)
Frame = +3
Query: 522 LKTFLQQPQLDHKDIMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
L FL + +L + I+G + ++L+A +DT + T S+ LY + R+
Sbjct: 293 LTHFLFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRH 336
>S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D
24-hydroxylase cytochrome P450 subunit protein.
Length = 257
Score = 34.3 bits (75), Expect = 0.39
Identities = 15/58 (25%), Positives = 30/58 (51%)
Frame = +3
Query: 480 NLFESDDSKNDKSLLKTFLQQPQLDHKDIMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
N E + L Q +L K++ + ++ +AA++TTA + ++LY++ RN
Sbjct: 31 NRLEKYSQQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRN 88
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 34.3 bits (75), Expect = 0.39
Identities = 15/58 (25%), Positives = 30/58 (51%)
Frame = +3
Query: 480 NLFESDDSKNDKSLLKTFLQQPQLDHKDIMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
N E + L Q +L K++ + ++ +AA++TTA + ++LY++ RN
Sbjct: 287 NRLEKYSQQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRN 344
>BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 34.3 bits (75), Expect = 0.39
Identities = 15/58 (25%), Positives = 30/58 (51%)
Frame = +3
Query: 480 NLFESDDSKNDKSLLKTFLQQPQLDHKDIMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
N E + L Q +L K++ + ++ +AA++TTA + ++LY++ RN
Sbjct: 288 NRLEKYSQQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRN 345
>BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 34.3 bits (75), Expect = 0.39
Identities = 15/58 (25%), Positives = 30/58 (51%)
Frame = +3
Query: 480 NLFESDDSKNDKSLLKTFLQQPQLDHKDIMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
N E + L Q +L K++ + ++ +AA++TTA + ++LY++ RN
Sbjct: 288 NRLEKYSQQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRN 345
>AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylase
splice variant protein.
Length = 372
Score = 34.3 bits (75), Expect = 0.39
Identities = 15/58 (25%), Positives = 30/58 (51%)
Frame = +3
Query: 480 NLFESDDSKNDKSLLKTFLQQPQLDHKDIMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
N E + L Q +L K++ + ++ +AA++TTA + ++LY++ RN
Sbjct: 146 NRLEKYSQQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRN 203
>AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 448
Score = 34.3 bits (75), Expect = 0.39
Identities = 15/58 (25%), Positives = 30/58 (51%)
Frame = +3
Query: 480 NLFESDDSKNDKSLLKTFLQQPQLDHKDIMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
N E + L Q +L K++ + ++ +AA++TTA + ++LY++ RN
Sbjct: 288 NRLEKYSQQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRN 345
>AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 34.3 bits (75), Expect = 0.39
Identities = 15/58 (25%), Positives = 30/58 (51%)
Frame = +3
Query: 480 NLFESDDSKNDKSLLKTFLQQPQLDHKDIMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
N E + L Q +L K++ + ++ +AA++TTA + ++LY++ RN
Sbjct: 288 NRLEKYSQQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRN 345
>AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 372
Score = 34.3 bits (75), Expect = 0.39
Identities = 15/58 (25%), Positives = 30/58 (51%)
Frame = +3
Query: 480 NLFESDDSKNDKSLLKTFLQQPQLDHKDIMGMMVDILMAAIDTTAYTTSFVLYHIXRN 653
N E + L Q +L K++ + ++ +AA++TTA + ++LY++ RN
Sbjct: 146 NRLEKYSQQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRN 203
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 85,778,388
Number of Sequences: 237096
Number of extensions: 1612259
Number of successful extensions: 2533
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 2394
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2533
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7310122300
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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