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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fprWP01_F_G09
         (655 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI00015B4C48 Cluster: PREDICTED: similar to cullin 1; ...    87   3e-16
UniRef50_Q4TBZ8 Cluster: Chromosome undetermined SCAF7068, whole...    84   3e-15
UniRef50_UPI0000EBC7A7 Cluster: PREDICTED: hypothetical protein ...    81   2e-14
UniRef50_Q6QRN4 Cluster: Cullin 1; n=2; Eutheria|Rep: Cullin 1 -...    81   2e-14
UniRef50_Q13616 Cluster: Cullin-1; n=49; Eukaryota|Rep: Cullin-1...    81   3e-14
UniRef50_Q5C3S3 Cluster: SJCHGC03444 protein; n=1; Schistosoma j...    54   2e-06
UniRef50_Q675W7 Cluster: Cullin; n=1; Oikopleura dioica|Rep: Cul...    54   4e-06
UniRef50_Q17389 Cluster: Cullin-1; n=2; Caenorhabditis|Rep: Cull...    49   1e-04
UniRef50_Q21346 Cluster: Cullin-6; n=1; Caenorhabditis elegans|R...    47   5e-04
UniRef50_Q54XF7 Cluster: Putative uncharacterized protein; n=1; ...    41   0.030
UniRef50_O13790 Cluster: Cullin-1; n=2; Schizosaccharomyces pomb...    40   0.039
UniRef50_Q5K745 Cluster: Ubiquitin-protein ligase, putative; n=2...    38   0.16 
UniRef50_Q0IEU9 Cluster: Cullin; n=1; Aedes aegypti|Rep: Cullin ...    38   0.28 
UniRef50_A3LP00 Cluster: Ubiquitin ligase (Cullin) of SCF involv...    37   0.49 
UniRef50_Q2H329 Cluster: Putative uncharacterized protein; n=1; ...    36   0.64 
UniRef50_Q6C9B4 Cluster: Similar to sp|Q12018 Saccharomyces cere...    36   0.85 
UniRef50_A0KM85 Cluster: Putative membrane protein; n=2; Gammapr...    36   1.1  
UniRef50_Q5CUE5 Cluster: Putative uncharacterized protein; n=2; ...    36   1.1  
UniRef50_Q7RKH0 Cluster: Sodium/hydrogen exchanger family protei...    34   3.4  
UniRef50_Q9V2Q2 Cluster: NrdD anaerobic ribonucleoside triphosph...    33   4.5  
UniRef50_UPI00006D0DB9 Cluster: Sodium/calcium exchanger protein...    33   6.0  
UniRef50_A6PUA2 Cluster: Glycoside hydrolase family 2, sugar bin...    33   6.0  

>UniRef50_UPI00015B4C48 Cluster: PREDICTED: similar to cullin 1;
           n=2; Apocrita|Rep: PREDICTED: similar to cullin 1 -
           Nasonia vitripennis
          Length = 810

 Score = 87.4 bits (207), Expect = 3e-16
 Identities = 41/68 (60%), Positives = 52/68 (76%), Gaps = 2/68 (2%)
 Frame = +3

Query: 426 STSNANRPQVPLRQKDFDQIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTSVHH-- 599
           S+ ++N+    L+Q D DQIWGDL+EGIEQVY +Q M K RYI+LYTHVYNYCTSVH   
Sbjct: 42  SSHSSNQGPPGLKQIDLDQIWGDLKEGIEQVYNRQCMSKPRYIELYTHVYNYCTSVHQQI 101

Query: 600 HSAGSSSR 623
           +S+  SS+
Sbjct: 102 NSSRQSSK 109


>UniRef50_Q4TBZ8 Cluster: Chromosome undetermined SCAF7068, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF7068,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 796

 Score = 83.8 bits (198), Expect = 3e-15
 Identities = 39/64 (60%), Positives = 46/64 (71%), Gaps = 2/64 (3%)
 Frame = +3

Query: 435 NANRPQVP--LRQKDFDQIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTSVHHHSA 608
           ++NR Q P  LRQ   DQIW DL+ GI+QVY +Q M K RY++LYTHVYNYCTSVH  S 
Sbjct: 2   SSNRTQNPHGLRQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSSQ 61

Query: 609 GSSS 620
           G  S
Sbjct: 62  GRGS 65


>UniRef50_UPI0000EBC7A7 Cluster: PREDICTED: hypothetical protein
           isoform 3; n=1; Bos taurus|Rep: PREDICTED: hypothetical
           protein isoform 3 - Bos taurus
          Length = 776

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 37/67 (55%), Positives = 47/67 (70%), Gaps = 2/67 (2%)
 Frame = +3

Query: 435 NANRPQVP--LRQKDFDQIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTSVHHHSA 608
           ++NR Q P  L+Q   DQIW DL+ GI+QVY +Q M K RY++LYTHVYNYCTSVH  + 
Sbjct: 2   SSNRSQNPHGLKQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSNQ 61

Query: 609 GSSSRVP 629
              + VP
Sbjct: 62  ARGAGVP 68


>UniRef50_Q6QRN4 Cluster: Cullin 1; n=2; Eutheria|Rep: Cullin 1 -
           Bos taurus (Bovine)
          Length = 187

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 37/67 (55%), Positives = 47/67 (70%), Gaps = 2/67 (2%)
 Frame = +3

Query: 435 NANRPQVP--LRQKDFDQIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTSVHHHSA 608
           ++NR Q P  L+Q   DQIW DL+ GI+QVY +Q M K RY++LYTHVYNYCTSVH  + 
Sbjct: 2   SSNRSQNPHGLKQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSNQ 61

Query: 609 GSSSRVP 629
              + VP
Sbjct: 62  ARGAGVP 68


>UniRef50_Q13616 Cluster: Cullin-1; n=49; Eukaryota|Rep: Cullin-1 -
           Homo sapiens (Human)
          Length = 776

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 36/69 (52%), Positives = 47/69 (68%)
 Frame = +3

Query: 423 MSTSNANRPQVPLRQKDFDQIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTSVHHH 602
           MS++ +  P   L+Q   DQIW DL+ GI+QVY +Q M K RY++LYTHVYNYCTSVH  
Sbjct: 1   MSSTRSQNPH-GLKQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQS 59

Query: 603 SAGSSSRVP 629
           +    + VP
Sbjct: 60  NQARGAGVP 68


>UniRef50_Q5C3S3 Cluster: SJCHGC03444 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC03444 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 195

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 20/47 (42%), Positives = 34/47 (72%)
 Frame = +3

Query: 483 IWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTSVHHHSAGSSSR 623
           +W DL+ G + +++ + + ++RY++L+THVYNYCTSV   S  + SR
Sbjct: 11  VWDDLKNGFDAIFRLETIKRKRYMELHTHVYNYCTSVDPKSHTTPSR 57


>UniRef50_Q675W7 Cluster: Cullin; n=1; Oikopleura dioica|Rep: Cullin
           - Oikopleura dioica (Tunicate)
          Length = 770

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 20/40 (50%), Positives = 30/40 (75%)
 Frame = +3

Query: 477 DQIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTSVH 596
           ++ W ++QEG+  V+    M  +RYI+LYTHVYNYCT+V+
Sbjct: 13  ERTWAEVQEGLNNVFFHHGMGHKRYIELYTHVYNYCTAVN 52


>UniRef50_Q17389 Cluster: Cullin-1; n=2; Caenorhabditis|Rep:
           Cullin-1 - Caenorhabditis elegans
          Length = 780

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 17/41 (41%), Positives = 29/41 (70%)
 Frame = +3

Query: 471 DFDQIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTSV 593
           D + +W  LQ+G++  Y+++ M  + Y+ LYT VY+YCTS+
Sbjct: 12  DSEVVWKKLQDGLDVAYRRENMAPKDYMTLYTSVYDYCTSI 52


>UniRef50_Q21346 Cluster: Cullin-6; n=1; Caenorhabditis elegans|Rep:
           Cullin-6 - Caenorhabditis elegans
          Length = 729

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 17/48 (35%), Positives = 33/48 (68%)
 Frame = +3

Query: 477 DQIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTSVHHHSAGSSS 620
           + +WG LQ+G+  +Y++++M K+ Y+ LY  VYN CT+    ++ ++S
Sbjct: 4   EAVWGTLQDGLNLLYRREHMSKKYYMMLYDAVYNICTTTTLANSNNNS 51


>UniRef50_Q54XF7 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 750

 Score = 40.7 bits (91), Expect = 0.030
 Identities = 13/42 (30%), Positives = 30/42 (71%), Gaps = 2/42 (4%)
 Frame = +3

Query: 477 DQIWGDLQEGIEQVYK--KQYMVKRRYIDLYTHVYNYCTSVH 596
           D++W + ++  E ++   K+ + ++RY+++YT +YNYC+S +
Sbjct: 8   DELWAECEQTFEDLFLNLKKGLSRKRYMEIYTKIYNYCSSAN 49


>UniRef50_O13790 Cluster: Cullin-1; n=2; Schizosaccharomyces
           pombe|Rep: Cullin-1 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 767

 Score = 40.3 bits (90), Expect = 0.039
 Identities = 19/59 (32%), Positives = 37/59 (62%), Gaps = 5/59 (8%)
 Frame = +3

Query: 423 MSTSNANRPQVPLRQKDFDQI---WGDLQEGIEQVYKK--QYMVKRRYIDLYTHVYNYC 584
           M+T N N   +P+ +K +D +   W  L+ G+ Q++++  + M   +Y++LYT ++NYC
Sbjct: 1   MTTLNTNDKDLPIVKK-YDSLNGTWDFLKTGVSQIFERLDEGMTITKYMELYTAIHNYC 58


>UniRef50_Q5K745 Cluster: Ubiquitin-protein ligase, putative; n=2;
           Filobasidiella neoformans|Rep: Ubiquitin-protein ligase,
           putative - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 775

 Score = 38.3 bits (85), Expect = 0.16
 Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
 Frame = +3

Query: 426 STSNANRPQVPLRQKDFDQIWGDLQEGIEQVYKKQY--MVKRRYIDLYTHVYNYCT 587
           S +   + Q P +  D  Q W  L  G++ +  +    M    YI LYT +YNYCT
Sbjct: 9   SWTEPTKAQAPPKDADLKQAWAFLSVGVDHIMTRLSFGMSYSYYILLYTAIYNYCT 64


>UniRef50_Q0IEU9 Cluster: Cullin; n=1; Aedes aegypti|Rep: Cullin -
           Aedes aegypti (Yellowfever mosquito)
          Length = 757

 Score = 37.5 bits (83), Expect = 0.28
 Identities = 14/40 (35%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
 Frame = +3

Query: 468 KDFDQIWGDLQEGIEQVYKKQYMVK-RRYIDLYTHVYNYC 584
           K  D+ W  L +GI ++Y+++  +   R++  +T+VYNYC
Sbjct: 23  KQQDETWTKLSDGIGRLYRQEESLNLERFLQYHTYVYNYC 62


>UniRef50_A3LP00 Cluster: Ubiquitin ligase (Cullin) of SCF involved
           in cell cycle control; n=5; Saccharomycetales|Rep:
           Ubiquitin ligase (Cullin) of SCF involved in cell cycle
           control - Pichia stipitis (Yeast)
          Length = 776

 Score = 36.7 bits (81), Expect = 0.49
 Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 3/53 (5%)
 Frame = +3

Query: 471 DFDQIWGDLQEGIEQVYKKQY---MVKRRYIDLYTHVYNYCTSVHHHSAGSSS 620
           D +  W  +Q G+E +   Q    +  + Y++ YT VYNYC +   H A ++S
Sbjct: 8   DLNATWSFIQPGLEFILGAQGDQGVTPKMYMNCYTAVYNYCVNKSRHGATATS 60


>UniRef50_Q2H329 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 724

 Score = 36.3 bits (80), Expect = 0.64
 Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 9/68 (13%)
 Frame = +3

Query: 447 PQVPLRQKDFDQIWGDLQEGIEQVYK--KQYMVKRRYIDLYTHVYNYCTS-------VHH 599
           P  P++  D D  W  LQ+GI  +    +Q +  + Y+ +YT V+N+CTS       +  
Sbjct: 10  PMQPVKD-DIDTTWTYLQDGITMIMMNLQQGIDLQTYMGIYTAVHNFCTSQKAVGFALQS 68

Query: 600 HSAGSSSR 623
           H  GSS R
Sbjct: 69  HVIGSSQR 76


>UniRef50_Q6C9B4 Cluster: Similar to sp|Q12018 Saccharomyces
           cerevisiae YDL132w CDC53 controls G1/S transition; n=1;
           Yarrowia lipolytica|Rep: Similar to sp|Q12018
           Saccharomyces cerevisiae YDL132w CDC53 controls G1/S
           transition - Yarrowia lipolytica (Candida lipolytica)
          Length = 788

 Score = 35.9 bits (79), Expect = 0.85
 Identities = 17/55 (30%), Positives = 30/55 (54%), Gaps = 5/55 (9%)
 Frame = +3

Query: 441 NRPQVPLRQKDFDQIWGDLQEGIEQVYKKQY-----MVKRRYIDLYTHVYNYCTS 590
           N P +P R  D D  W  +++G+ QV +        +  + Y++LY+ ++NYC S
Sbjct: 3   NTPPLP-RADDIDATWKYIEDGVGQVLRDDLAHGAGLSSQMYMNLYSAIHNYCVS 56


>UniRef50_A0KM85 Cluster: Putative membrane protein; n=2;
           Gammaproteobacteria|Rep: Putative membrane protein -
           Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966
           / NCIB 9240)
          Length = 357

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 16/46 (34%), Positives = 30/46 (65%)
 Frame = -2

Query: 375 FCFN*IYSLKNVSIRLLIPLQNAML*SLITSRNHSVGSDYFTLIFI 238
           FC   +YS++N    L++ L   ++  LI++  ++VGSDYF+ ++I
Sbjct: 9   FCSLYMYSVQNYKASLIVLLPPFIIYFLISALQYNVGSDYFSYLYI 54


>UniRef50_Q5CUE5 Cluster: Putative uncharacterized protein; n=2;
           Cryptosporidium|Rep: Putative uncharacterized protein -
           Cryptosporidium parvum Iowa II
          Length = 311

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 13/48 (27%), Positives = 28/48 (58%)
 Frame = -1

Query: 361 NIFTEKRIDPITNSVTKCNAIKLNNE*KSQCWQRLFYFNIYIT*LFVF 218
           ++F   +  PI N++   N   L N+ K++ +QR  YF +++  +++F
Sbjct: 195 SLFIVSKYQPIVNNIQIINIFDLANKNKNKLYQRKAYFEVFVVGIYIF 242


>UniRef50_Q7RKH0 Cluster: Sodium/hydrogen exchanger family protein,
            putative; n=3; Plasmodium (Vinckeia)|Rep: Sodium/hydrogen
            exchanger family protein, putative - Plasmodium yoelii
            yoelii
          Length = 1688

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 19/66 (28%), Positives = 34/66 (51%), Gaps = 15/66 (22%)
 Frame = +3

Query: 444  RPQVPLRQKDFDQI---------------WGDLQEGIEQVYKKQYMVKRRYIDLYTHVYN 578
            RP++ ++ K FDQI               +G L++G+   Y+KQ + K R  +LY  ++N
Sbjct: 1395 RPKIKIQSKQFDQIRRSRSHENYRKNKDKYGKLKDGVFHSYRKQIIRKEREGELYIMIFN 1454

Query: 579  YCTSVH 596
             C  ++
Sbjct: 1455 TCKELY 1460


>UniRef50_Q9V2Q2 Cluster: NrdD anaerobic ribonucleoside triphosphate
           reductase; n=8; Archaea|Rep: NrdD anaerobic
           ribonucleoside triphosphate reductase - Pyrococcus
           abyssi
          Length = 658

 Score = 33.5 bits (73), Expect = 4.5
 Identities = 16/59 (27%), Positives = 31/59 (52%), Gaps = 3/59 (5%)
 Frame = +3

Query: 423 MSTSNANRPQVPLRQKDFDQIWGDLQEGIEQVYKKQYMVKRRYIDL---YTHVYNYCTS 590
           ++ +  N P++ L+ +D D+ W + +  +E V       + RYI L   Y H+Y+  T+
Sbjct: 370 INVTTVNLPRIALKARDDDEFWEEYERVLEIVRITTEWFRDRYISLIRNYPHMYSMITT 428


>UniRef50_UPI00006D0DB9 Cluster: Sodium/calcium exchanger protein;
            n=1; Tetrahymena thermophila SB210|Rep: Sodium/calcium
            exchanger protein - Tetrahymena thermophila SB210
          Length = 5392

 Score = 33.1 bits (72), Expect = 6.0
 Identities = 13/41 (31%), Positives = 27/41 (65%)
 Frame = +3

Query: 468  KDFDQIWGDLQEGIEQVYKKQYMVKRRYIDLYTHVYNYCTS 590
            K FD+I  ++ E IEQ+ K+  ++ ++ I+ ++H+ +Y  S
Sbjct: 4484 KTFDEIKKNMNENIEQIKKETLLIAQKVIEDFSHLNSYYES 4524


>UniRef50_A6PUA2 Cluster: Glycoside hydrolase family 2, sugar
           binding; n=1; Victivallis vadensis ATCC BAA-548|Rep:
           Glycoside hydrolase family 2, sugar binding -
           Victivallis vadensis ATCC BAA-548
          Length = 215

 Score = 33.1 bits (72), Expect = 6.0
 Identities = 16/40 (40%), Positives = 23/40 (57%)
 Frame = +2

Query: 446 TPSAAAAKGL*SDMGRSSRGNRTSLQKTVHGQETIHRSVY 565
           TP  AAAKG+ +++G  +  +RT L  T  G    H+ VY
Sbjct: 111 TPEQAAAKGMRAELGHINTADRTFLNGTQIGAADEHKRVY 150


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 563,549,429
Number of Sequences: 1657284
Number of extensions: 10249677
Number of successful extensions: 24123
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 23412
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 24114
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 49173558301
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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