Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fprWP01_F_E02
(609 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC002849-1|AAH02849.1| 177|Homo sapiens coatomer protein comple... 207 3e-53
AF151878-1|AAD34115.1| 177|Homo sapiens CGI-120 protein protein. 207 3e-53
AF086911-1|AAP97141.1| 177|Homo sapiens z-cop protein. 207 3e-53
AB047848-1|BAB17659.1| 177|Homo sapiens zeta1-COP protein. 207 3e-53
AK223188-1|BAD96908.1| 177|Homo sapiens coatomer protein comple... 205 1e-52
BC015924-1|AAH15924.1| 210|Homo sapiens coatomer protein comple... 176 6e-44
AB047849-1|BAB17660.1| 210|Homo sapiens zeta2-COP protein. 176 6e-44
AB037938-1|BAA90670.1| 210|Homo sapiens nonclathrin coat protei... 176 6e-44
CR457100-1|CAG33381.1| 144|Homo sapiens AP4S1 protein. 39 0.012
AF155159-1|AAD43329.1| 144|Homo sapiens adaptor-related protein... 39 0.012
AB030654-1|BAA82970.1| 144|Homo sapiens AP-4 clathrin adaptor-r... 39 0.012
Z69744-1|CAA93625.1| 4005|Homo sapiens ALL-1 protein protein. 32 1.8
L22179-1|AAC37520.1| 2311|Homo sapiens MLL-AF4 der(11) fusion pr... 32 1.8
L04284-1|AAA58669.1| 3969|Homo sapiens HRX protein. 32 1.8
D14540-1|BAA03407.1| 1909|Homo sapiens MLL protein. 32 1.8
AY373585-1|AAQ63624.1| 3969|Homo sapiens myeloid/lymphoid or mix... 32 1.8
AB015319-1|BAA33391.1| 158|Homo sapiens sigma1A subunit of AP-1... 30 7.3
AC004876-2|AAD45829.1| 157|Homo sapiens clathrin coat assembly ... 29 9.7
>BC002849-1|AAH02849.1| 177|Homo sapiens coatomer protein complex,
subunit zeta 1 protein.
Length = 177
Score = 207 bits (505), Expect = 3e-53
Identities = 94/155 (60%), Positives = 127/155 (81%)
Frame = +2
Query: 101 KVLXFEPTLYIVKGMCILDYEGNRILAKYYDKDVLPTTKEQKAFEKNLFNKTHRANAEII 280
+ L EP+LY VK + ILD +G+R+ AKYYD D P+ KEQKAFEKN+FNKTHR ++EI
Sbjct: 2 EALILEPSLYTVKAILILDNDGDRLFAKYYD-DTYPSVKEQKAFEKNIFNKTHRTDSEIA 60
Query: 281 MLDGLTCVYKSNVDLFFYVMGSSHENELILQSVLNALYESVSLLLRRNMERRVLMENLDA 460
+L+GLT VYKS++DL+FYV+GSS+ENEL+L +VLN L++S+S +LR+N+E+R L+EN++
Sbjct: 61 LLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEG 120
Query: 461 VMLAFDEICDGGVILDADPTSIVSRAALRTEDVPL 565
+ LA DEI DGGVIL++DP +V R ALR EDVPL
Sbjct: 121 LFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPL 155
>AF151878-1|AAD34115.1| 177|Homo sapiens CGI-120 protein protein.
Length = 177
Score = 207 bits (505), Expect = 3e-53
Identities = 94/155 (60%), Positives = 127/155 (81%)
Frame = +2
Query: 101 KVLXFEPTLYIVKGMCILDYEGNRILAKYYDKDVLPTTKEQKAFEKNLFNKTHRANAEII 280
+ L EP+LY VK + ILD +G+R+ AKYYD D P+ KEQKAFEKN+FNKTHR ++EI
Sbjct: 2 EALILEPSLYTVKAILILDNDGDRLFAKYYD-DTYPSVKEQKAFEKNIFNKTHRTDSEIA 60
Query: 281 MLDGLTCVYKSNVDLFFYVMGSSHENELILQSVLNALYESVSLLLRRNMERRVLMENLDA 460
+L+GLT VYKS++DL+FYV+GSS+ENEL+L +VLN L++S+S +LR+N+E+R L+EN++
Sbjct: 61 LLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEG 120
Query: 461 VMLAFDEICDGGVILDADPTSIVSRAALRTEDVPL 565
+ LA DEI DGGVIL++DP +V R ALR EDVPL
Sbjct: 121 LFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPL 155
>AF086911-1|AAP97141.1| 177|Homo sapiens z-cop protein.
Length = 177
Score = 207 bits (505), Expect = 3e-53
Identities = 94/155 (60%), Positives = 127/155 (81%)
Frame = +2
Query: 101 KVLXFEPTLYIVKGMCILDYEGNRILAKYYDKDVLPTTKEQKAFEKNLFNKTHRANAEII 280
+ L EP+LY VK + ILD +G+R+ AKYYD D P+ KEQKAFEKN+FNKTHR ++EI
Sbjct: 2 EALILEPSLYTVKAILILDNDGDRLFAKYYD-DTYPSVKEQKAFEKNIFNKTHRTDSEIA 60
Query: 281 MLDGLTCVYKSNVDLFFYVMGSSHENELILQSVLNALYESVSLLLRRNMERRVLMENLDA 460
+L+GLT VYKS++DL+FYV+GSS+ENEL+L +VLN L++S+S +LR+N+E+R L+EN++
Sbjct: 61 LLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEG 120
Query: 461 VMLAFDEICDGGVILDADPTSIVSRAALRTEDVPL 565
+ LA DEI DGGVIL++DP +V R ALR EDVPL
Sbjct: 121 LFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPL 155
>AB047848-1|BAB17659.1| 177|Homo sapiens zeta1-COP protein.
Length = 177
Score = 207 bits (505), Expect = 3e-53
Identities = 94/155 (60%), Positives = 127/155 (81%)
Frame = +2
Query: 101 KVLXFEPTLYIVKGMCILDYEGNRILAKYYDKDVLPTTKEQKAFEKNLFNKTHRANAEII 280
+ L EP+LY VK + ILD +G+R+ AKYYD D P+ KEQKAFEKN+FNKTHR ++EI
Sbjct: 2 EALILEPSLYTVKAILILDNDGDRLFAKYYD-DTYPSVKEQKAFEKNIFNKTHRTDSEIA 60
Query: 281 MLDGLTCVYKSNVDLFFYVMGSSHENELILQSVLNALYESVSLLLRRNMERRVLMENLDA 460
+L+GLT VYKS++DL+FYV+GSS+ENEL+L +VLN L++S+S +LR+N+E+R L+EN++
Sbjct: 61 LLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEG 120
Query: 461 VMLAFDEICDGGVILDADPTSIVSRAALRTEDVPL 565
+ LA DEI DGGVIL++DP +V R ALR EDVPL
Sbjct: 121 LFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPL 155
>AK223188-1|BAD96908.1| 177|Homo sapiens coatomer protein complex,
subunit zeta 1 variant protein.
Length = 177
Score = 205 bits (500), Expect = 1e-52
Identities = 93/155 (60%), Positives = 126/155 (81%)
Frame = +2
Query: 101 KVLXFEPTLYIVKGMCILDYEGNRILAKYYDKDVLPTTKEQKAFEKNLFNKTHRANAEII 280
+ L EP+LY VK + ILD +G+R+ AKYYD D P+ KEQKAFEKN+FNKTHR ++EI
Sbjct: 2 EALILEPSLYTVKAILILDNDGDRLFAKYYD-DTYPSVKEQKAFEKNIFNKTHRTDSEIA 60
Query: 281 MLDGLTCVYKSNVDLFFYVMGSSHENELILQSVLNALYESVSLLLRRNMERRVLMENLDA 460
+L+GLT VYKS++DL+FYV+GSS+ENEL+L +VLN L++S+ +LR+N+E+R L+EN++
Sbjct: 61 LLEGLTVVYKSSIDLYFYVIGSSYENELMLMAVLNCLFDSLRQMLRKNVEKRALLENMEG 120
Query: 461 VMLAFDEICDGGVILDADPTSIVSRAALRTEDVPL 565
+ LA DEI DGGVIL++DP +V R ALR EDVPL
Sbjct: 121 LFLAVDEIVDGGVILESDPQQVVHRVALRGEDVPL 155
>BC015924-1|AAH15924.1| 210|Homo sapiens coatomer protein complex,
subunit zeta 2 protein.
Length = 210
Score = 176 bits (428), Expect = 6e-44
Identities = 79/147 (53%), Positives = 109/147 (74%)
Frame = +2
Query: 116 EPTLYIVKGMCILDYEGNRILAKYYDKDVLPTTKEQKAFEKNLFNKTHRANAEIIMLDGL 295
EP+LY +K + ILD +G R+LAKYYD D P+ KEQ FEKN+FNKT R +EI G+
Sbjct: 40 EPSLYTIKAVFILDNDGRRLLAKYYD-DTFPSMKEQMVFEKNVFNKTSRTESEIAFFGGM 98
Query: 296 TCVYKSNVDLFFYVMGSSHENELILQSVLNALYESVSLLLRRNMERRVLMENLDAVMLAF 475
T VYK+++DLF YV+GSS+ENEL+L SVL L+ES++ +LR+N+E+R L+EN+D L
Sbjct: 99 TIVYKNSIDLFLYVVGSSYENELMLMSVLTCLFESLNHMLRKNVEKRWLLENMDGAFLVL 158
Query: 476 DEICDGGVILDADPTSIVSRAALRTED 556
DEI DGGVIL++DP ++ + R +D
Sbjct: 159 DEIVDGGVILESDPQQVIQKVNFRADD 185
>AB047849-1|BAB17660.1| 210|Homo sapiens zeta2-COP protein.
Length = 210
Score = 176 bits (428), Expect = 6e-44
Identities = 79/147 (53%), Positives = 109/147 (74%)
Frame = +2
Query: 116 EPTLYIVKGMCILDYEGNRILAKYYDKDVLPTTKEQKAFEKNLFNKTHRANAEIIMLDGL 295
EP+LY +K + ILD +G R+LAKYYD D P+ KEQ FEKN+FNKT R +EI G+
Sbjct: 40 EPSLYTIKAVFILDNDGRRLLAKYYD-DTFPSMKEQMVFEKNVFNKTSRTESEIAFFGGM 98
Query: 296 TCVYKSNVDLFFYVMGSSHENELILQSVLNALYESVSLLLRRNMERRVLMENLDAVMLAF 475
T VYK+++DLF YV+GSS+ENEL+L SVL L+ES++ +LR+N+E+R L+EN+D L
Sbjct: 99 TIVYKNSIDLFLYVVGSSYENELMLMSVLTCLFESLNHMLRKNVEKRWLLENMDGAFLVL 158
Query: 476 DEICDGGVILDADPTSIVSRAALRTED 556
DEI DGGVIL++DP ++ + R +D
Sbjct: 159 DEIVDGGVILESDPQQVIQKVNFRADD 185
>AB037938-1|BAA90670.1| 210|Homo sapiens nonclathrin coat protein
zeta-COP protein.
Length = 210
Score = 176 bits (428), Expect = 6e-44
Identities = 79/147 (53%), Positives = 109/147 (74%)
Frame = +2
Query: 116 EPTLYIVKGMCILDYEGNRILAKYYDKDVLPTTKEQKAFEKNLFNKTHRANAEIIMLDGL 295
EP+LY +K + ILD +G R+LAKYYD D P+ KEQ FEKN+FNKT R +EI G+
Sbjct: 40 EPSLYTIKAVFILDNDGRRLLAKYYD-DTFPSMKEQMVFEKNVFNKTSRTESEIAFFGGM 98
Query: 296 TCVYKSNVDLFFYVMGSSHENELILQSVLNALYESVSLLLRRNMERRVLMENLDAVMLAF 475
T VYK+++DLF YV+GSS+ENEL+L SVL L+ES++ +LR+N+E+R L+EN+D L
Sbjct: 99 TIVYKNSIDLFLYVVGSSYENELMLMSVLTCLFESLNHMLRKNVEKRWLLENMDGAFLVL 158
Query: 476 DEICDGGVILDADPTSIVSRAALRTED 556
DEI DGGVIL++DP ++ + R +D
Sbjct: 159 DEIVDGGVILESDPQQVIQKVNFRADD 185
>CR457100-1|CAG33381.1| 144|Homo sapiens AP4S1 protein.
Length = 144
Score = 39.1 bits (87), Expect = 0.012
Identities = 29/135 (21%), Positives = 61/135 (45%), Gaps = 1/135 (0%)
Frame = +2
Query: 131 IVKGMCILDYEGNRILAKYYDK-DVLPTTKEQKAFEKNLFNKTHRANAEIIMLDGLTCVY 307
++K +++ +G L+KYY+ D+ T + K+ ++++ I +Y
Sbjct: 1 MIKFFLMVNKQGQTRLSKYYEHVDINKRTLLETEVIKSCLSRSNE-QCSFIEYKDFKLIY 59
Query: 308 KSNVDLFFYVMGSSHENELILQSVLNALYESVSLLLRRNMERRVLMENLDAVMLAFDEIC 487
+ LF V + ENE+ + ++ E + R E ++ NLD V + DE+
Sbjct: 60 RQYAALFIVVGVNDTENEMAIYEFIHNFVEVLDEYFSRVSELDIMF-NLDKVHIILDEMV 118
Query: 488 DGGVILDADPTSIVS 532
G I++ + I++
Sbjct: 119 LNGCIVETNRARILA 133
>AF155159-1|AAD43329.1| 144|Homo sapiens adaptor-related protein
complex AP-4 sigma4 subunit protein.
Length = 144
Score = 39.1 bits (87), Expect = 0.012
Identities = 29/135 (21%), Positives = 61/135 (45%), Gaps = 1/135 (0%)
Frame = +2
Query: 131 IVKGMCILDYEGNRILAKYYDK-DVLPTTKEQKAFEKNLFNKTHRANAEIIMLDGLTCVY 307
++K +++ +G L+KYY+ D+ T + K+ ++++ I +Y
Sbjct: 1 MIKFFLMVNKQGQTRLSKYYEHVDINKRTLLETEVIKSCLSRSNE-QCSFIEYKDFKLIY 59
Query: 308 KSNVDLFFYVMGSSHENELILQSVLNALYESVSLLLRRNMERRVLMENLDAVMLAFDEIC 487
+ LF V + ENE+ + ++ E + R E ++ NLD V + DE+
Sbjct: 60 RQYAALFIVVGVNDTENEMAIYEFIHNFVEVLDEYFSRVSELDIMF-NLDKVHIILDEMV 118
Query: 488 DGGVILDADPTSIVS 532
G I++ + I++
Sbjct: 119 LNGCIVETNRARILA 133
>AB030654-1|BAA82970.1| 144|Homo sapiens AP-4 clathrin
adaptor-related complex sigma4 subunit protein.
Length = 144
Score = 39.1 bits (87), Expect = 0.012
Identities = 29/135 (21%), Positives = 61/135 (45%), Gaps = 1/135 (0%)
Frame = +2
Query: 131 IVKGMCILDYEGNRILAKYYDK-DVLPTTKEQKAFEKNLFNKTHRANAEIIMLDGLTCVY 307
++K +++ +G L+KYY+ D+ T + K+ ++++ I +Y
Sbjct: 1 MIKFFLMVNKQGQTRLSKYYEHVDINKRTLLETEVIKSCLSRSNE-QCSFIEYKDFKLIY 59
Query: 308 KSNVDLFFYVMGSSHENELILQSVLNALYESVSLLLRRNMERRVLMENLDAVMLAFDEIC 487
+ LF V + ENE+ + ++ E + R E ++ NLD V + DE+
Sbjct: 60 RQYAALFIVVGVNDTENEMAIYEFIHNFVEVLDEYFSRVSELDIMF-NLDKVHIILDEMV 118
Query: 488 DGGVILDADPTSIVS 532
G I++ + I++
Sbjct: 119 LNGCIVETNRARILA 133
>Z69744-1|CAA93625.1| 4005|Homo sapiens ALL-1 protein protein.
Length = 4005
Score = 31.9 bits (69), Expect = 1.8
Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
Frame = -1
Query: 591 VXGPLFALPRGTSSVRSAARLTIDVGSASNITPPSQISSKASITASKFSMRTLRSMFLL- 415
V P+ + PR S + S +TPPS +SS SI+ S + L F
Sbjct: 773 VFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFP 832
Query: 414 SSKLTDS 394
S LT S
Sbjct: 833 SHSLTQS 839
>L22179-1|AAC37520.1| 2311|Homo sapiens MLL-AF4 der(11) fusion
protein protein.
Length = 2311
Score = 31.9 bits (69), Expect = 1.8
Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
Frame = -1
Query: 591 VXGPLFALPRGTSSVRSAARLTIDVGSASNITPPSQISSKASITASKFSMRTLRSMFLL- 415
V P+ + PR S + S +TPPS +SS SI+ S + L F
Sbjct: 781 VFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFP 840
Query: 414 SSKLTDS 394
S LT S
Sbjct: 841 SHSLTQS 847
>L04284-1|AAA58669.1| 3969|Homo sapiens HRX protein.
Length = 3969
Score = 31.9 bits (69), Expect = 1.8
Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
Frame = -1
Query: 591 VXGPLFALPRGTSSVRSAARLTIDVGSASNITPPSQISSKASITASKFSMRTLRSMFLL- 415
V P+ + PR S + S +TPPS +SS SI+ S + L F
Sbjct: 740 VFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFP 799
Query: 414 SSKLTDS 394
S LT S
Sbjct: 800 SHSLTQS 806
>D14540-1|BAA03407.1| 1909|Homo sapiens MLL protein.
Length = 1909
Score = 31.9 bits (69), Expect = 1.8
Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
Frame = -1
Query: 591 VXGPLFALPRGTSSVRSAARLTIDVGSASNITPPSQISSKASITASKFSMRTLRSMFLL- 415
V P+ + PR S + S +TPPS +SS SI+ S + L F
Sbjct: 740 VFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFP 799
Query: 414 SSKLTDS 394
S LT S
Sbjct: 800 SHSLTQS 806
>AY373585-1|AAQ63624.1| 3969|Homo sapiens myeloid/lymphoid or
mixed-lineage leukemia (trithorax homolog, Drosophila)
protein.
Length = 3969
Score = 31.9 bits (69), Expect = 1.8
Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
Frame = -1
Query: 591 VXGPLFALPRGTSSVRSAARLTIDVGSASNITPPSQISSKASITASKFSMRTLRSMFLL- 415
V P+ + PR S + S +TPPS +SS SI+ S + L F
Sbjct: 740 VFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFP 799
Query: 414 SSKLTDS 394
S LT S
Sbjct: 800 SHSLTQS 806
>AB015319-1|BAA33391.1| 158|Homo sapiens sigma1A subunit of AP-1
clathrin adaptor complex protein.
Length = 158
Score = 29.9 bits (64), Expect = 7.3
Identities = 28/136 (20%), Positives = 52/136 (38%), Gaps = 3/136 (2%)
Frame = +2
Query: 131 IVKGMCILDYEGNRILAKYYDKDVLPTTKEQKAFEKNLFNKTHRANAEIIML---DGLTC 301
+++ M + +G L K+Y + + KE+K + L ++ L
Sbjct: 1 MMRFMLLFSRQGKLRLQKWY---LATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKV 57
Query: 302 VYKSNVDLFFYVMGSSHENELILQSVLNALYESVSLLLRRNMERRVLMENLDAVMLAFDE 481
VYK L+F +NELI +++ E + E ++ N + DE
Sbjct: 58 VYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIF-NFEKAYFILDE 116
Query: 482 ICDGGVILDADPTSIV 529
GG + D S++
Sbjct: 117 FLMGGDVQDTSKKSVL 132
>AC004876-2|AAD45829.1| 157|Homo sapiens clathrin coat assembly
protein AP19 protein.
Length = 157
Score = 29.5 bits (63), Expect = 9.7
Identities = 28/132 (21%), Positives = 49/132 (37%), Gaps = 3/132 (2%)
Frame = +2
Query: 143 MCILDYEGNRILAKYYDKDVLPTTKEQKAFEKNLFNKTHRANAEIIML---DGLTCVYKS 313
M + +G L K+Y + + KE+K + L ++ L VYK
Sbjct: 4 MLLFSRQGKLRLQKWY---LATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKR 60
Query: 314 NVDLFFYVMGSSHENELILQSVLNALYESVSLLLRRNMERRVLMENLDAVMLAFDEICDG 493
L+F +NELI +++ E + E ++ N + DE G
Sbjct: 61 YASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIF-NFEKAYFILDEFLMG 119
Query: 494 GVILDADPTSIV 529
G + D S++
Sbjct: 120 GDVQDTSKKSVL 131
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 88,181,053
Number of Sequences: 237096
Number of extensions: 1765009
Number of successful extensions: 7882
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 7742
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7874
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6466646650
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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