Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner12n19r
(722 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U36308-1|AAC02794.2| 263|Homo sapiens lens major intrinsic prot... 72 2e-12
BC117474-1|AAI17475.1| 263|Homo sapiens major intrinsic protein... 72 2e-12
BC074913-1|AAH74913.1| 263|Homo sapiens major intrinsic protein... 72 2e-12
BC040630-1|AAH40630.1| 255|Homo sapiens AQP8 protein protein. 72 2e-12
AK222975-1|BAD96695.1| 261|Homo sapiens aquaporin 8 variant pro... 72 2e-12
AK222964-1|BAD96684.1| 261|Homo sapiens aquaporin 8 variant pro... 72 2e-12
AF067797-1|AAF19050.1| 261|Homo sapiens aquaporin 8 protein. 72 2e-12
AB013456-1|BAA34223.1| 261|Homo sapiens aquaporin 8 protein. 71 3e-12
CR542024-1|CAG46821.1| 271|Homo sapiens AQP2 protein. 71 4e-12
Z29491-1|CAA82627.1| 271|Homo sapiens water channel aquaporin-2... 70 1e-11
U63623-1|AAB26958.1| 301|Homo sapiens aquaporin 4 protein. 70 1e-11
U63622-1|AAB26957.1| 323|Homo sapiens aquaporin 4 protein. 70 1e-11
U34846-1|AAC52112.1| 341|Homo sapiens mercurial-insensitive wat... 70 1e-11
U34845-1|AAC50284.1| 301|Homo sapiens mercurial-insensitive wat... 70 1e-11
D63412-1|BAA09715.1| 323|Homo sapiens aquaporin protein. 70 1e-11
D31846-1|BAA06632.1| 271|Homo sapiens human aquaporin-2 water c... 70 1e-11
BC042496-1|AAH42496.1| 271|Homo sapiens aquaporin 2 (collecting... 70 1e-11
BC022286-1|AAH22286.1| 323|Homo sapiens aquaporin 4 protein. 70 1e-11
AK222684-1|BAD96404.1| 323|Homo sapiens aquaporin 4 isoform a v... 70 1e-11
AF147093-1|AAD38692.1| 271|Homo sapiens aquaporin 2 protein. 70 1e-11
AF000143-1|AAC03168.1| 263|Homo sapiens putative alternative le... 69 1e-11
S73197-1|AAB31998.1| 271|Homo sapiens water-channel aquaporin 2... 66 9e-11
S73196-1|AAB31999.1| 271|Homo sapiens water-channel aquaporin 2... 66 9e-11
U46569-1|AAC50474.1| 265|Homo sapiens aquaporin-5 protein. 61 3e-09
CR542022-1|CAG46819.1| 265|Homo sapiens AQP5 protein. 61 3e-09
CR541989-1|CAG46786.1| 265|Homo sapiens AQP5 protein. 61 3e-09
BC032946-1|AAH32946.1| 265|Homo sapiens aquaporin 5 protein. 61 3e-09
U48408-1|AAB41566.1| 282|Homo sapiens water channel protein. 58 3e-08
U41517-1|AAC50648.1| 269|Homo sapiens channel-like integral mem... 52 2e-06
S73482-1|AAB31193.1| 269|Homo sapiens uterine water channel pro... 52 2e-06
M77829-1|AAA58425.1| 269|Homo sapiens channel-like integral mem... 52 2e-06
BC022486-1|AAH22486.1| 269|Homo sapiens aquaporin 1 (Colton blo... 52 2e-06
AY953319-1|AAX24129.1| 269|Homo sapiens aquaporin 1 (channel-fo... 52 2e-06
AF480415-1|AAL87136.1| 265|Homo sapiens aquaporin 1 protein. 52 2e-06
AB128929-1|BAD22823.1| 218|Homo sapiens aquaporin type4 transcr... 52 2e-06
AC004691-1|AAC16481.1| 128|Homo sapiens unknown protein. 41 0.004
DQ083949-1|AAY68214.1| 292|Homo sapiens aquaporin 3 protein. 40 0.009
CR542025-1|CAG46822.1| 292|Homo sapiens AQP3 protein. 40 0.009
CR541991-1|CAG46788.1| 292|Homo sapiens AQP3 protein. 40 0.009
BT007199-1|AAP35863.1| 292|Homo sapiens aquaporin 3 protein. 40 0.009
BC013566-1|AAH13566.1| 292|Homo sapiens aquaporin 3 (Gill blood... 40 0.009
AL356218-9|CAI13311.1| 292|Homo sapiens aquaporin 3 (Gill blood... 40 0.009
AJ493597-1|CAD38526.1| 281|Homo sapiens aquaporin-3 protein. 40 0.009
AB001325-1|BAA19237.1| 292|Homo sapiens aquaporin 3 protein. 40 0.009
AB209156-1|BAD92393.1| 219|Homo sapiens aquaporin 4 isoform a v... 38 0.048
U41518-1|AAC50649.1| 152|Homo sapiens channel-like integral mem... 36 0.11
AC005155-1|AAC23788.1| 141|Homo sapiens aquaporin protein. 36 0.11
BC062701-1|AAH62701.1| 216|Homo sapiens AQP7 protein protein. 33 1.0
AL356218-8|CAI13309.1| 342|Homo sapiens aquaporin 7 protein. 33 1.0
AL356218-7|CAI13308.1| 256|Homo sapiens aquaporin 7 protein. 33 1.0
AL356218-6|CAI13307.1| 341|Homo sapiens aquaporin 7 protein. 33 1.0
AB052626-1|BAC05693.1| 342|Homo sapiens aquaporin adipose protein. 33 1.0
AB006190-1|BAA21745.1| 342|Homo sapiens aquaporin adipose protein. 33 1.0
CR542027-1|CAG46824.1| 295|Homo sapiens AQP9 protein. 32 1.8
BC026258-1|AAH26258.1| 295|Homo sapiens AQP9 protein protein. 32 1.8
AF016495-1|AAF16677.1| 295|Homo sapiens small solute channel 1 ... 32 1.8
AB008775-1|BAA24864.1| 295|Homo sapiens aquaporin 9 protein. 32 1.8
AY312581-1|AAR16186.1| 81|Homo sapiens aquaporin 1 splice vari... 32 2.4
AY312580-1|AAR16185.1| 135|Homo sapiens aquaporin 1 splice vari... 32 2.4
BC074897-1|AAH74897.1| 301|Homo sapiens aquaporin 10 protein. 31 3.2
BC074896-1|AAH74896.1| 301|Homo sapiens aquaporin 10 protein. 31 3.2
BC069607-1|AAH69607.1| 301|Homo sapiens aquaporin 10 protein. 31 3.2
AL354980-5|CAH70483.1| 301|Homo sapiens aquaporin 10 protein. 31 3.2
AL354980-4|CAH70482.1| 264|Homo sapiens aquaporin 10 protein. 31 3.2
AF159174-1|AAL25998.1| 264|Homo sapiens small intestine aquapor... 31 3.2
AB066105-1|BAB91223.1| 301|Homo sapiens aquaporin 10 protein. 31 3.2
AL137070-3|CAD13298.1| 346|Homo sapiens bA251O17.3 (similar to ... 31 5.5
AB037742-1|BAA92559.1| 714|Homo sapiens KIAA1321 protein protein. 30 7.3
>U36308-1|AAC02794.2| 263|Homo sapiens lens major intrinsic protein
protein.
Length = 263
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/166 (30%), Positives = 66/166 (39%), Gaps = 2/166 (1%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
A AFG + + G SGAH+NPAVT A + +MS A Y AQ+
Sbjct: 45 AMAFGLALATLVQSVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYMAAQLLGAVAGAAVL 104
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDE--SGPDPMV 319
+VTP + G L C ++ +DE +G V
Sbjct: 105 YSVTPPAVRGN---LALNTLHPAVSVGQATTVEIFLTLQFVLC-IFATYDERRNGQLGSV 160
Query: 318 PVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TGA +NPARSFAPA+ G + HWVYWV
Sbjct: 161 ALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWV 206
>BC117474-1|AAI17475.1| 263|Homo sapiens major intrinsic protein of
lens fiber protein.
Length = 263
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/166 (30%), Positives = 66/166 (39%), Gaps = 2/166 (1%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
A AFG + + G SGAH+NPAVT A + +MS A Y AQ+
Sbjct: 45 AMAFGLALATLVQSVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYMAAQLLGAVAGAAVL 104
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDE--SGPDPMV 319
+VTP + G L C ++ +DE +G V
Sbjct: 105 YSVTPPAVRGN---LALNTLHPAVSVGQATTVEIFLTLQFVLC-IFATYDERRNGQLGSV 160
Query: 318 PVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TGA +NPARSFAPA+ G + HWVYWV
Sbjct: 161 ALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWV 206
>BC074913-1|AAH74913.1| 263|Homo sapiens major intrinsic protein of
lens fiber protein.
Length = 263
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/166 (30%), Positives = 66/166 (39%), Gaps = 2/166 (1%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
A AFG + + G SGAH+NPAVT A + +MS A Y AQ+
Sbjct: 45 AMAFGLALATLVQSVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYMAAQLLGAVAGAAVL 104
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDE--SGPDPMV 319
+VTP + G L C ++ +DE +G V
Sbjct: 105 YSVTPPAVRGN---LALNTLHPAVSVGQATTVEIFLTLQFVLC-IFATYDERRNGQLGSV 160
Query: 318 PVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TGA +NPARSFAPA+ G + HWVYWV
Sbjct: 161 ALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWV 206
>BC040630-1|AAH40630.1| 255|Homo sapiens AQP8 protein protein.
Length = 255
Score = 71.7 bits (168), Expect = 2e-12
Identities = 46/169 (27%), Positives = 64/169 (37%), Gaps = 1/169 (0%)
Frame = -3
Query: 684 LSHPAFAFGFVVLGNAMA-FGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXX 508
L PA A G + LG +A G SG H NPAV+LAA L G ++ + Y V+Q+
Sbjct: 59 LLQPALAHG-LALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGML 117
Query: 507 XXXXXXAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPD 328
AV+P G A A +E
Sbjct: 118 GAALAKAVSPEERFWNASGAAFVTVQEQGQVAGALVAEIILTTLLALAVCMGAINEKTKG 177
Query: 327 PMVPVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
P+ P +G +NPAR+F PA+ W +HW+YW+
Sbjct: 178 PLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWL 226
>AK222975-1|BAD96695.1| 261|Homo sapiens aquaporin 8 variant
protein.
Length = 261
Score = 71.7 bits (168), Expect = 2e-12
Identities = 46/169 (27%), Positives = 64/169 (37%), Gaps = 1/169 (0%)
Frame = -3
Query: 684 LSHPAFAFGFVVLGNAMA-FGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXX 508
L PA A G + LG +A G SG H NPAV+LAA L G ++ + Y V+Q+
Sbjct: 65 LLQPALAHG-LALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGML 123
Query: 507 XXXXXXAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPD 328
AV+P G A A +E
Sbjct: 124 GAALAKAVSPEERFWNASGAAFVTVQEQGQVAGALVAEIILTTLLALAVCMGAINEKTKG 183
Query: 327 PMVPVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
P+ P +G +NPAR+F PA+ W +HW+YW+
Sbjct: 184 PLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWL 232
>AK222964-1|BAD96684.1| 261|Homo sapiens aquaporin 8 variant
protein.
Length = 261
Score = 71.7 bits (168), Expect = 2e-12
Identities = 46/169 (27%), Positives = 64/169 (37%), Gaps = 1/169 (0%)
Frame = -3
Query: 684 LSHPAFAFGFVVLGNAMA-FGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXX 508
L PA A G + LG +A G SG H NPAV+LAA L G ++ + Y V+Q+
Sbjct: 65 LLQPALAHG-LALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGML 123
Query: 507 XXXXXXAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPD 328
AV+P G A A +E
Sbjct: 124 GAALAKAVSPEERFWNASGAAFVTVQEQGQVAGALVAEIILTTLLALAVCMGAINEKTKG 183
Query: 327 PMVPVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
P+ P +G +NPAR+F PA+ W +HW+YW+
Sbjct: 184 PLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWL 232
>AF067797-1|AAF19050.1| 261|Homo sapiens aquaporin 8 protein.
Length = 261
Score = 71.7 bits (168), Expect = 2e-12
Identities = 46/169 (27%), Positives = 64/169 (37%), Gaps = 1/169 (0%)
Frame = -3
Query: 684 LSHPAFAFGFVVLGNAMA-FGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXX 508
L PA A G + LG +A G SG H NPAV+LAA L G ++ + Y V+Q+
Sbjct: 65 LLQPALAHG-LALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGML 123
Query: 507 XXXXXXAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPD 328
AV+P G A A +E
Sbjct: 124 GAALAKAVSPEERFWNASGAAFVTVQEQGQVAGALVAEIILTTLLALAVCMGAINEKTKG 183
Query: 327 PMVPVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
P+ P +G +NPAR+F PA+ W +HW+YW+
Sbjct: 184 PLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWL 232
>AB013456-1|BAA34223.1| 261|Homo sapiens aquaporin 8 protein.
Length = 261
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/169 (26%), Positives = 63/169 (37%), Gaps = 1/169 (0%)
Frame = -3
Query: 684 LSHPAFAFGFVVLGNAMA-FGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXX 508
L PA A G + LG +A G SG H NPAV+LAA L G ++ + Y V+Q+
Sbjct: 65 LLQPALAHG-LALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGML 123
Query: 507 XXXXXXAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPD 328
V+P G A A +E
Sbjct: 124 GAALAKVVSPEERFWNASGAAFVTVQEQGQVAGALVAEIILTTLLALAVCMGAINEKTKG 183
Query: 327 PMVPVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
P+ P +G +NPAR+F PA+ W +HW+YW+
Sbjct: 184 PLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWL 232
>CR542024-1|CAG46821.1| 271|Homo sapiens AQP2 protein.
Length = 271
Score = 70.9 bits (166), Expect = 4e-12
Identities = 46/165 (27%), Positives = 62/165 (37%), Gaps = 1/165 (0%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
A AFG + A G SGAH+NPAVT+A + +S AA Y AQ+
Sbjct: 45 AMAFGLGIGTRVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALL 104
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPMVP- 316
+TPA G + C + G +P P
Sbjct: 105 HEITPADIRG---DLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPA 161
Query: 315 VKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TG S+NPARS APA+ G + HWV+W+
Sbjct: 162 LSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWI 206
>Z29491-1|CAA82627.1| 271|Homo sapiens water channel aquaporin-2
protein.
Length = 271
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/165 (27%), Positives = 62/165 (37%), Gaps = 1/165 (0%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
A AFG + A G SGAH+NPAVT+A + +S AA Y AQ+
Sbjct: 45 AMAFGLGIGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALL 104
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPMVP- 316
+TPA G + C + G +P P
Sbjct: 105 HEITPADIRG---DLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPA 161
Query: 315 VKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TG S+NPARS APA+ G + HWV+W+
Sbjct: 162 LSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWI 206
>U63623-1|AAB26958.1| 301|Homo sapiens aquaporin 4 protein.
Length = 301
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/166 (27%), Positives = 64/166 (38%), Gaps = 2/166 (1%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
+ FG + FG SG H+NPAVT+A ++S A + Y AQ
Sbjct: 52 SLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGIL 111
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPM--V 319
VTP S +G G T+ ++ + D D +
Sbjct: 112 YLVTPPSVVG-GLGVTMVHGNLTAGHGLLVELIITFQLVFT---IFASCDSKRTDVTGSI 167
Query: 318 PVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TGAS+NPARSF PA+ G W+ HW+YWV
Sbjct: 168 ALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWV 213
>U63622-1|AAB26957.1| 323|Homo sapiens aquaporin 4 protein.
Length = 323
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/166 (27%), Positives = 64/166 (38%), Gaps = 2/166 (1%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
+ FG + FG SG H+NPAVT+A ++S A + Y AQ
Sbjct: 74 SLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGIL 133
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPM--V 319
VTP S +G G T+ ++ + D D +
Sbjct: 134 YLVTPPSVVG-GLGVTMVHGNLTAGHGLLVELIITFQLVFT---IFASCDSKRTDVTGSI 189
Query: 318 PVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TGAS+NPARSF PA+ G W+ HW+YWV
Sbjct: 190 ALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWV 235
>U34846-1|AAC52112.1| 341|Homo sapiens mercurial-insensitive water
channel protein.
Length = 341
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/166 (27%), Positives = 64/166 (38%), Gaps = 2/166 (1%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
+ FG + FG SG H+NPAVT+A ++S A + Y AQ
Sbjct: 92 SLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGIL 151
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPM--V 319
VTP S +G G T+ ++ + D D +
Sbjct: 152 YLVTPPSVVG-GLGVTMVHGNLTAGHGLLVELIITFQLVFT---IFASCDSKRTDVTGSI 207
Query: 318 PVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TGAS+NPARSF PA+ G W+ HW+YWV
Sbjct: 208 ALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWV 253
>U34845-1|AAC50284.1| 301|Homo sapiens mercurial-insensitive water
channel protein.
Length = 301
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/166 (27%), Positives = 64/166 (38%), Gaps = 2/166 (1%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
+ FG + FG SG H+NPAVT+A ++S A + Y AQ
Sbjct: 52 SLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGIL 111
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPM--V 319
VTP S +G G T+ ++ + D D +
Sbjct: 112 YLVTPPSVVG-GLGVTMVHGNLTAGHGLLVELIITFQLVFT---IFASCDSKRTDVTGSI 167
Query: 318 PVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TGAS+NPARSF PA+ G W+ HW+YWV
Sbjct: 168 ALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWV 213
>D63412-1|BAA09715.1| 323|Homo sapiens aquaporin protein.
Length = 323
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/166 (27%), Positives = 64/166 (38%), Gaps = 2/166 (1%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
+ FG + FG SG H+NPAVT+A ++S A + Y AQ
Sbjct: 74 SLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGIL 133
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPM--V 319
VTP S +G G T+ ++ + D D +
Sbjct: 134 YLVTPPSVVG-GLGVTMVHGNLTAGHGLLVELIITFQLVFT---IFASCDSKRTDVTGSI 189
Query: 318 PVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TGAS+NPARSF PA+ G W+ HW+YWV
Sbjct: 190 ALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWV 235
>D31846-1|BAA06632.1| 271|Homo sapiens human aquaporin-2 water
channel protein.
Length = 271
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/165 (27%), Positives = 62/165 (37%), Gaps = 1/165 (0%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
A AFG + A G SGAH+NPAVT+A + +S AA Y AQ+
Sbjct: 45 AMAFGLGIGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALL 104
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPMVP- 316
+TPA G + C + G +P P
Sbjct: 105 HEITPADIRG---DLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPA 161
Query: 315 VKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TG S+NPARS APA+ G + HWV+W+
Sbjct: 162 LSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWI 206
>BC042496-1|AAH42496.1| 271|Homo sapiens aquaporin 2 (collecting
duct) protein.
Length = 271
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/165 (27%), Positives = 62/165 (37%), Gaps = 1/165 (0%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
A AFG + A G SGAH+NPAVT+A + +S AA Y AQ+
Sbjct: 45 AMAFGLGIGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALL 104
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPMVP- 316
+TPA G + C + G +P P
Sbjct: 105 HEITPADIRG---DLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPA 161
Query: 315 VKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TG S+NPARS APA+ G + HWV+W+
Sbjct: 162 LSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWI 206
>BC022286-1|AAH22286.1| 323|Homo sapiens aquaporin 4 protein.
Length = 323
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/166 (27%), Positives = 64/166 (38%), Gaps = 2/166 (1%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
+ FG + FG SG H+NPAVT+A ++S A + Y AQ
Sbjct: 74 SLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGIL 133
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPM--V 319
VTP S +G G T+ ++ + D D +
Sbjct: 134 YLVTPPSVVG-GLGVTMVHGNLTAGHGLLVELIITFQLVFT---IFASCDSKRTDVTGSI 189
Query: 318 PVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TGAS+NPARSF PA+ G W+ HW+YWV
Sbjct: 190 ALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWV 235
>AK222684-1|BAD96404.1| 323|Homo sapiens aquaporin 4 isoform a
variant protein.
Length = 323
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/166 (27%), Positives = 64/166 (38%), Gaps = 2/166 (1%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
+ FG + FG SG H+NPAVT+A ++S A + Y AQ
Sbjct: 74 SLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGIL 133
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPM--V 319
VTP S +G G T+ ++ + D D +
Sbjct: 134 YLVTPPSVVG-GLGVTMVHGNLTAGHGLLVELIITFQLVFT---IFASCDSKRTDVTGSI 189
Query: 318 PVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TGAS+NPARSF PA+ G W+ HW+YWV
Sbjct: 190 ALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWV 235
>AF147093-1|AAD38692.1| 271|Homo sapiens aquaporin 2 protein.
Length = 271
Score = 69.7 bits (163), Expect = 1e-11
Identities = 46/165 (27%), Positives = 62/165 (37%), Gaps = 1/165 (0%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
A AFG + A G SGAH+NPAVT+A + +S AA Y AQ+
Sbjct: 45 AMAFGLGIGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALL 104
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPMVP- 316
+TPA G + C + G +P P
Sbjct: 105 HEITPADIRG---DLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPA 161
Query: 315 VKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TG S+NPARS APA+ G + HWV+W+
Sbjct: 162 LSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWI 206
>AF000143-1|AAC03168.1| 263|Homo sapiens putative alternative lens
membrane intrinsic protein protein.
Length = 263
Score = 69.3 bits (162), Expect = 1e-11
Identities = 49/166 (29%), Positives = 64/166 (38%), Gaps = 2/166 (1%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
A AFG + G SGAH+NPAVT A + +MS A Y AQ+
Sbjct: 45 ALAFGLALATLVQTVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYIAAQLLGAVAGAAVL 104
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDE--SGPDPMV 319
+VTP + G L C ++ +DE +G V
Sbjct: 105 YSVTPPAVRGN---LALNTLHAGVSVGQATTVEIFLTLQFVLC-IFATYDERRNGRMGSV 160
Query: 318 PVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TGA +NPARSFAPA+ + HWVYWV
Sbjct: 161 ALAVGFSLTLGHLFGMYYTGAGMNPARSFAPAILTRNFSNHWVYWV 206
>S73197-1|AAB31998.1| 271|Homo sapiens water-channel aquaporin 2
protein.
Length = 271
Score = 66.5 bits (155), Expect = 9e-11
Identities = 45/165 (27%), Positives = 61/165 (36%), Gaps = 1/165 (0%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
A AFG + A G S AH+NPAVT+A + +S AA Y AQ+
Sbjct: 45 AMAFGLGIGTLVQALGHISRAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALL 104
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPMVP- 316
+TPA G + C + G +P P
Sbjct: 105 HEITPADIRGD---LAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPA 161
Query: 315 VKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TG S+NPARS APA+ G + HWV+W+
Sbjct: 162 LSIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWI 206
>S73196-1|AAB31999.1| 271|Homo sapiens water-channel aquaporin 2
protein.
Length = 271
Score = 66.5 bits (155), Expect = 9e-11
Identities = 45/165 (27%), Positives = 61/165 (36%), Gaps = 1/165 (0%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
A AFG + A G SGAH+NPAVT+A + +S AA Y AQ+
Sbjct: 45 AMAFGLGIGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALL 104
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPMVP- 316
+TPA G + C + G +P P
Sbjct: 105 HEITPADIRG---DLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPA 161
Query: 315 VKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TG S+NPA S APA+ G + HWV+W+
Sbjct: 162 LSIGFSVALGHLLGIHYTGCSMNPACSLAPAVVTGKFDDHWVFWI 206
>U46569-1|AAC50474.1| 265|Homo sapiens aquaporin-5 protein.
Length = 265
Score = 61.3 bits (142), Expect = 3e-09
Identities = 46/167 (27%), Positives = 64/167 (38%), Gaps = 3/167 (1%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
A AFG + A A GP SG H+NPA+TLA + ++S A Y AQ+
Sbjct: 46 ALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGIL 105
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPM--V 319
V P +A G + A C ++ + D P+
Sbjct: 106 YGVAPLNARG---NLAVNALNNNTTQGQAMVVELILTFQLALC-IFASTDSRRTSPVGSP 161
Query: 318 PVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQ-YHWVYWV 181
+ TG S+NPARSF PA+ + HWV+WV
Sbjct: 162 ALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWV 208
>CR542022-1|CAG46819.1| 265|Homo sapiens AQP5 protein.
Length = 265
Score = 61.3 bits (142), Expect = 3e-09
Identities = 46/167 (27%), Positives = 64/167 (38%), Gaps = 3/167 (1%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
A AFG + A A GP SG H+NPA+TLA + ++S A Y AQ+
Sbjct: 46 ALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGIL 105
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPM--V 319
V P +A G + A C ++ + D P+
Sbjct: 106 YGVAPLNARG---NLAVNALNNNTTQGQAMVVELILTFQLALC-IFASTDSRRTSPVGSP 161
Query: 318 PVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQ-YHWVYWV 181
+ TG S+NPARSF PA+ + HWV+WV
Sbjct: 162 ALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWV 208
>CR541989-1|CAG46786.1| 265|Homo sapiens AQP5 protein.
Length = 265
Score = 61.3 bits (142), Expect = 3e-09
Identities = 46/167 (27%), Positives = 64/167 (38%), Gaps = 3/167 (1%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
A AFG + A A GP SG H+NPA+TLA + ++S A Y AQ+
Sbjct: 46 ALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGIL 105
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPM--V 319
V P +A G + A C ++ + D P+
Sbjct: 106 YGVAPLNARG---NLAVNALNNNTTQGQAMVVELILTFQLALC-IFASTDSRRTSPVGSP 161
Query: 318 PVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQ-YHWVYWV 181
+ TG S+NPARSF PA+ + HWV+WV
Sbjct: 162 ALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWV 208
>BC032946-1|AAH32946.1| 265|Homo sapiens aquaporin 5 protein.
Length = 265
Score = 61.3 bits (142), Expect = 3e-09
Identities = 46/167 (27%), Positives = 64/167 (38%), Gaps = 3/167 (1%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
A AFG + A A GP SG H+NPA+TLA + ++S A Y AQ+
Sbjct: 46 ALAFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGIL 105
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPM--V 319
V P +A G + A C ++ + D P+
Sbjct: 106 YGVAPLNARG---NLAVNALNNNTTQGQAMVVELILTFQLALC-IFASTDSRRTSPVGSP 161
Query: 318 PVKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQ-YHWVYWV 181
+ TG S+NPARSF PA+ + HWV+WV
Sbjct: 162 ALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWV 208
>U48408-1|AAB41566.1| 282|Homo sapiens water channel protein.
Length = 282
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/165 (27%), Positives = 57/165 (34%), Gaps = 1/165 (0%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
A F V TSGAH NPAVTLA + +S A AY AQ+
Sbjct: 59 AITFNLVTAMAVQVTWKTSGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALL 118
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESG-PDPMVP 316
V P T G + + SG P M+
Sbjct: 119 YGVMPGDIRET-LGINVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQTSGSPATMIG 177
Query: 315 VKXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
+ TG S+NPARSF PA+ G + HWV+WV
Sbjct: 178 ISWALGHLIGILF----TGCSMNPARSFGPAIIIGKFTVHWVFWV 218
>U41517-1|AAC50648.1| 269|Homo sapiens channel-like integral
membrane protein protein.
Length = 269
Score = 52.4 bits (120), Expect = 2e-06
Identities = 40/164 (24%), Positives = 55/164 (33%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
+ AFG + A + G SGAH+NPAVTL L ++S A Y +AQ
Sbjct: 53 SLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAIL 112
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPMVPV 313
+T +S G G C P+
Sbjct: 113 SGIT-SSLTGNSLGRN-DLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPL 170
Query: 312 KXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
TG +NPARSF A+ + HW++WV
Sbjct: 171 AIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWV 214
>S73482-1|AAB31193.1| 269|Homo sapiens uterine water channel
protein.
Length = 269
Score = 52.4 bits (120), Expect = 2e-06
Identities = 40/164 (24%), Positives = 55/164 (33%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
+ AFG + A + G SGAH+NPAVTL L ++S A Y +AQ
Sbjct: 53 SLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAIL 112
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPMVPV 313
+T +S G G C P+
Sbjct: 113 SGIT-SSLTGNSLGRN-DLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPL 170
Query: 312 KXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
TG +NPARSF A+ + HW++WV
Sbjct: 171 AIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWV 214
>M77829-1|AAA58425.1| 269|Homo sapiens channel-like integral
membrane protein protein.
Length = 269
Score = 52.4 bits (120), Expect = 2e-06
Identities = 40/164 (24%), Positives = 55/164 (33%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
+ AFG + A + G SGAH+NPAVTL L ++S A Y +AQ
Sbjct: 53 SLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAIL 112
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPMVPV 313
+T +S G G C P+
Sbjct: 113 SGIT-SSLTGNSLGRN-DLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPL 170
Query: 312 KXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
TG +NPARSF A+ + HW++WV
Sbjct: 171 AIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWV 214
>BC022486-1|AAH22486.1| 269|Homo sapiens aquaporin 1 (Colton blood
group) protein.
Length = 269
Score = 52.4 bits (120), Expect = 2e-06
Identities = 40/164 (24%), Positives = 55/164 (33%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
+ AFG + A + G SGAH+NPAVTL L ++S A Y +AQ
Sbjct: 53 SLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAIL 112
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPMVPV 313
+T +S G G C P+
Sbjct: 113 SGIT-SSLTGNSLGRN-DLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPL 170
Query: 312 KXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
TG +NPARSF A+ + HW++WV
Sbjct: 171 AIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWV 214
>AY953319-1|AAX24129.1| 269|Homo sapiens aquaporin 1
(channel-forming integral protein, 28kDa) protein.
Length = 269
Score = 52.4 bits (120), Expect = 2e-06
Identities = 40/164 (24%), Positives = 55/164 (33%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
+ AFG + A + G SGAH+NPAVTL L ++S A Y +AQ
Sbjct: 53 SLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAIL 112
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPMVPV 313
+T +S G G C P+
Sbjct: 113 SGIT-SSLTGNSLGRN-DLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPL 170
Query: 312 KXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
TG +NPARSF A+ + HW++WV
Sbjct: 171 AIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWV 214
>AF480415-1|AAL87136.1| 265|Homo sapiens aquaporin 1 protein.
Length = 265
Score = 52.4 bits (120), Expect = 2e-06
Identities = 40/164 (24%), Positives = 55/164 (33%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
+ AFG + A + G SGAH+NPAVTL L ++S A Y +AQ
Sbjct: 49 SLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAIL 108
Query: 492 XAVTPASALGTDEGCTLPXXXXXXXXXXXXXXXXXXXXXXACCGVWKAHDESGPDPMVPV 313
+T +S G G C P+
Sbjct: 109 SGIT-SSLTGNSLGRN-DLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPL 166
Query: 312 KXXXXXXXXXXXXXXATGASLNPARSFAPALYHGIWQYHWVYWV 181
TG +NPARSF A+ + HW++WV
Sbjct: 167 AIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWV 210
>AB128929-1|BAD22823.1| 218|Homo sapiens aquaporin type4 transcript
variant c protein.
Length = 218
Score = 52.4 bits (120), Expect = 2e-06
Identities = 19/28 (67%), Positives = 23/28 (82%)
Frame = -3
Query: 264 TGASLNPARSFAPALYHGIWQYHWVYWV 181
TGAS+NPARSF PA+ G W+ HW+YWV
Sbjct: 103 TGASMNPARSFGPAVIMGNWENHWIYWV 130
>AC004691-1|AAC16481.1| 128|Homo sapiens unknown protein.
Length = 128
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/74 (33%), Positives = 34/74 (45%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQVXXXXXXXXXX 493
+ AFG + A + G SGAH+NPAVTL L ++S A Y +AQ
Sbjct: 53 SLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAIL 112
Query: 492 XAVTPASALGTDEG 451
+T +S G G
Sbjct: 113 SGIT-SSLTGNSLG 125
>DQ083949-1|AAY68214.1| 292|Homo sapiens aquaporin 3 protein.
Length = 292
Score = 39.9 bits (89), Expect = 0.009
Identities = 21/47 (44%), Positives = 24/47 (51%)
Frame = -3
Query: 666 AFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
AFGF V + G SGAH+NPAVT A R YT+AQ
Sbjct: 62 AFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQ 108
>CR542025-1|CAG46822.1| 292|Homo sapiens AQP3 protein.
Length = 292
Score = 39.9 bits (89), Expect = 0.009
Identities = 21/47 (44%), Positives = 24/47 (51%)
Frame = -3
Query: 666 AFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
AFGF V + G SGAH+NPAVT A R YT+AQ
Sbjct: 62 AFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQ 108
>CR541991-1|CAG46788.1| 292|Homo sapiens AQP3 protein.
Length = 292
Score = 39.9 bits (89), Expect = 0.009
Identities = 21/47 (44%), Positives = 24/47 (51%)
Frame = -3
Query: 666 AFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
AFGF V + G SGAH+NPAVT A R YT+AQ
Sbjct: 62 AFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQ 108
>BT007199-1|AAP35863.1| 292|Homo sapiens aquaporin 3 protein.
Length = 292
Score = 39.9 bits (89), Expect = 0.009
Identities = 21/47 (44%), Positives = 24/47 (51%)
Frame = -3
Query: 666 AFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
AFGF V + G SGAH+NPAVT A R YT+AQ
Sbjct: 62 AFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQ 108
>BC013566-1|AAH13566.1| 292|Homo sapiens aquaporin 3 (Gill blood
group) protein.
Length = 292
Score = 39.9 bits (89), Expect = 0.009
Identities = 21/47 (44%), Positives = 24/47 (51%)
Frame = -3
Query: 666 AFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
AFGF V + G SGAH+NPAVT A R YT+AQ
Sbjct: 62 AFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQ 108
>AL356218-9|CAI13311.1| 292|Homo sapiens aquaporin 3 (Gill blood
group) protein.
Length = 292
Score = 39.9 bits (89), Expect = 0.009
Identities = 21/47 (44%), Positives = 24/47 (51%)
Frame = -3
Query: 666 AFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
AFGF V + G SGAH+NPAVT A R YT+AQ
Sbjct: 62 AFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQ 108
>AJ493597-1|CAD38526.1| 281|Homo sapiens aquaporin-3 protein.
Length = 281
Score = 39.9 bits (89), Expect = 0.009
Identities = 21/47 (44%), Positives = 24/47 (51%)
Frame = -3
Query: 666 AFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
AFGF V + G SGAH+NPAVT A R YT+AQ
Sbjct: 62 AFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQ 108
>AB001325-1|BAA19237.1| 292|Homo sapiens aquaporin 3 protein.
Length = 292
Score = 39.9 bits (89), Expect = 0.009
Identities = 21/47 (44%), Positives = 24/47 (51%)
Frame = -3
Query: 666 AFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
AFGF V + G SGAH+NPAVT A R YT+AQ
Sbjct: 62 AFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQ 108
>AB209156-1|BAD92393.1| 219|Homo sapiens aquaporin 4 isoform a
variant protein.
Length = 219
Score = 37.5 bits (83), Expect = 0.048
Identities = 18/49 (36%), Positives = 25/49 (51%)
Frame = -3
Query: 672 AFAFGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
+ FG + FG SG H+NPAVT+A ++S A + Y AQ
Sbjct: 81 SLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQ 129
>U41518-1|AAC50649.1| 152|Homo sapiens channel-like integral
membrane protein protein.
Length = 152
Score = 36.3 bits (80), Expect = 0.11
Identities = 13/28 (46%), Positives = 18/28 (64%)
Frame = -3
Query: 264 TGASLNPARSFAPALYHGIWQYHWVYWV 181
TG +NPARSF A+ + HW++WV
Sbjct: 70 TGCGINPARSFGSAVITHNFSNHWIFWV 97
>AC005155-1|AAC23788.1| 141|Homo sapiens aquaporin protein.
Length = 141
Score = 36.3 bits (80), Expect = 0.11
Identities = 13/28 (46%), Positives = 18/28 (64%)
Frame = -3
Query: 264 TGASLNPARSFAPALYHGIWQYHWVYWV 181
TG +NPARSF A+ + HW++WV
Sbjct: 59 TGCGINPARSFGSAVITHNFSNHWIFWV 86
>BC062701-1|AAH62701.1| 216|Homo sapiens AQP7 protein protein.
Length = 216
Score = 33.1 bits (72), Expect = 1.0
Identities = 19/46 (41%), Positives = 21/46 (45%)
Frame = -3
Query: 663 FGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
FGF V G SGAHMN AVT A GR+ Y + Q
Sbjct: 17 FGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQ 62
>AL356218-8|CAI13309.1| 342|Homo sapiens aquaporin 7 protein.
Length = 342
Score = 33.1 bits (72), Expect = 1.0
Identities = 19/46 (41%), Positives = 21/46 (45%)
Frame = -3
Query: 663 FGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
FGF V G SGAHMN AVT A GR+ Y + Q
Sbjct: 74 FGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQ 119
>AL356218-7|CAI13308.1| 256|Homo sapiens aquaporin 7 protein.
Length = 256
Score = 33.1 bits (72), Expect = 1.0
Identities = 19/46 (41%), Positives = 21/46 (45%)
Frame = -3
Query: 663 FGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
FGF V G SGAHMN AVT A GR+ Y + Q
Sbjct: 73 FGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQ 118
>AL356218-6|CAI13307.1| 341|Homo sapiens aquaporin 7 protein.
Length = 341
Score = 33.1 bits (72), Expect = 1.0
Identities = 19/46 (41%), Positives = 21/46 (45%)
Frame = -3
Query: 663 FGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
FGF V G SGAHMN AVT A GR+ Y + Q
Sbjct: 73 FGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQ 118
>AB052626-1|BAC05693.1| 342|Homo sapiens aquaporin adipose protein.
Length = 342
Score = 33.1 bits (72), Expect = 1.0
Identities = 19/46 (41%), Positives = 21/46 (45%)
Frame = -3
Query: 663 FGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
FGF V G SGAHMN AVT A GR+ Y + Q
Sbjct: 74 FGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQ 119
>AB006190-1|BAA21745.1| 342|Homo sapiens aquaporin adipose protein.
Length = 342
Score = 33.1 bits (72), Expect = 1.0
Identities = 19/46 (41%), Positives = 21/46 (45%)
Frame = -3
Query: 663 FGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
FGF V G SGAHMN AVT A GR+ Y + Q
Sbjct: 74 FGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQ 119
>CR542027-1|CAG46824.1| 295|Homo sapiens AQP9 protein.
Length = 295
Score = 32.3 bits (70), Expect = 1.8
Identities = 17/34 (50%), Positives = 19/34 (55%)
Frame = -3
Query: 627 GPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
G SG H+NPAV+LA L GRM Y AQ
Sbjct: 76 GGVSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQ 109
>BC026258-1|AAH26258.1| 295|Homo sapiens AQP9 protein protein.
Length = 295
Score = 32.3 bits (70), Expect = 1.8
Identities = 17/34 (50%), Positives = 19/34 (55%)
Frame = -3
Query: 627 GPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
G SG H+NPAV+LA L GRM Y AQ
Sbjct: 76 GGVSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQ 109
>AF016495-1|AAF16677.1| 295|Homo sapiens small solute channel 1
protein.
Length = 295
Score = 32.3 bits (70), Expect = 1.8
Identities = 17/34 (50%), Positives = 19/34 (55%)
Frame = -3
Query: 627 GPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
G SG H+NPAV+LA L GRM Y AQ
Sbjct: 76 GGVSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQ 109
>AB008775-1|BAA24864.1| 295|Homo sapiens aquaporin 9 protein.
Length = 295
Score = 32.3 bits (70), Expect = 1.8
Identities = 17/34 (50%), Positives = 19/34 (55%)
Frame = -3
Query: 627 GPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQ 526
G SG H+NPAV+LA L GRM Y AQ
Sbjct: 76 GGVSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQ 109
>AY312581-1|AAR16186.1| 81|Homo sapiens aquaporin 1 splice variant
3 protein.
Length = 81
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/24 (45%), Positives = 16/24 (66%)
Frame = -3
Query: 252 LNPARSFAPALYHGIWQYHWVYWV 181
+NPARSF A+ + HW++WV
Sbjct: 3 INPARSFGSAVITHNFSNHWIFWV 26
>AY312580-1|AAR16185.1| 135|Homo sapiens aquaporin 1 splice variant
2 protein.
Length = 135
Score = 31.9 bits (69), Expect = 2.4
Identities = 11/24 (45%), Positives = 16/24 (66%)
Frame = -3
Query: 252 LNPARSFAPALYHGIWQYHWVYWV 181
+NPARSF A+ + HW++WV
Sbjct: 3 INPARSFGSAVITHNFSNHWIFWV 26
>BC074897-1|AAH74897.1| 301|Homo sapiens aquaporin 10 protein.
Length = 301
Score = 31.5 bits (68), Expect = 3.2
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = -3
Query: 627 GPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQV 523
G SGAH+NPA +LA + GR+ Y + Q+
Sbjct: 74 GNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQL 108
>BC074896-1|AAH74896.1| 301|Homo sapiens aquaporin 10 protein.
Length = 301
Score = 31.5 bits (68), Expect = 3.2
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = -3
Query: 627 GPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQV 523
G SGAH+NPA +LA + GR+ Y + Q+
Sbjct: 74 GNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQL 108
>BC069607-1|AAH69607.1| 301|Homo sapiens aquaporin 10 protein.
Length = 301
Score = 31.5 bits (68), Expect = 3.2
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = -3
Query: 627 GPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQV 523
G SGAH+NPA +LA + GR+ Y + Q+
Sbjct: 74 GNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQL 108
>AL354980-5|CAH70483.1| 301|Homo sapiens aquaporin 10 protein.
Length = 301
Score = 31.5 bits (68), Expect = 3.2
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = -3
Query: 627 GPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQV 523
G SGAH+NPA +LA + GR+ Y + Q+
Sbjct: 74 GNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQL 108
>AL354980-4|CAH70482.1| 264|Homo sapiens aquaporin 10 protein.
Length = 264
Score = 31.5 bits (68), Expect = 3.2
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = -3
Query: 627 GPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQV 523
G SGAH+NPA +LA + GR+ Y + Q+
Sbjct: 74 GNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQL 108
>AF159174-1|AAL25998.1| 264|Homo sapiens small intestine aquaporin
protein.
Length = 264
Score = 31.5 bits (68), Expect = 3.2
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = -3
Query: 627 GPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQV 523
G SGAH+NPA +LA + GR+ Y + Q+
Sbjct: 74 GNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQL 108
>AB066105-1|BAB91223.1| 301|Homo sapiens aquaporin 10 protein.
Length = 301
Score = 31.5 bits (68), Expect = 3.2
Identities = 14/35 (40%), Positives = 20/35 (57%)
Frame = -3
Query: 627 GPTSGAHMNPAVTLAAALQGRMSPALAAAYTVAQV 523
G SGAH+NPA +LA + GR+ Y + Q+
Sbjct: 74 GNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQL 108
>AL137070-3|CAD13298.1| 346|Homo sapiens bA251O17.3 (similar to
aquaporin 7) protein.
Length = 346
Score = 30.7 bits (66), Expect = 5.5
Identities = 16/34 (47%), Positives = 17/34 (50%)
Frame = -3
Query: 663 FGFVVLGNAMAFGPTSGAHMNPAVTLAAALQGRM 562
FGF V G SGAHMN AVT GR+
Sbjct: 78 FGFGVTMGVHVAGRISGAHMNAAVTFTNCALGRV 111
>AB037742-1|BAA92559.1| 714|Homo sapiens KIAA1321 protein protein.
Length = 714
Score = 30.3 bits (65), Expect = 7.3
Identities = 12/25 (48%), Positives = 13/25 (52%)
Frame = +1
Query: 250 QASSRRVSPGENQPGHHESQLHGHH 324
Q S PG+ QP HH S H HH
Sbjct: 16 QPLSMEEKPGQPQPQHHHSHHHPHH 40
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 76,936,161
Number of Sequences: 237096
Number of extensions: 1127462
Number of successful extensions: 4076
Number of sequences better than 10.0: 68
Number of HSP's better than 10.0 without gapping: 3743
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4061
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8511181328
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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