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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fner12m23f
         (406 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P26735 Cluster: Bombyxin C-2 precursor (BBX-C2) (4K-pro...    95   4e-19
UniRef50_O61271 Cluster: Bombyxin G-1 precursor (BBX-G1) [Contai...    93   2e-18
UniRef50_P21808 Cluster: Bombyxin E-1 precursor (BBX-E1) (Bombyx...    88   5e-17
UniRef50_P91896 Cluster: Bombyxin F-1 precursor (BBX-F1) [Contai...    81   6e-15
UniRef50_O09209 Cluster: Bombyxin-related peptide A precursor (A...    65   4e-10
UniRef50_P33719 Cluster: Bombyxin A-2 homolog precursor [Contain...    61   9e-09
UniRef50_Q17196 Cluster: Bombyxin B-11 precursor (BBX-B11) (4K-p...    55   6e-07
UniRef50_A0EZS0 Cluster: Insulin-like peptide 6 splice variant A...    50   2e-05
UniRef50_A0EZR7 Cluster: Insulin-like peptide 2; n=2; Aedes aegy...    39   0.033
UniRef50_A0EZS2 Cluster: Insulin-like peptide 7; n=1; Aedes aegy...    37   0.13 
UniRef50_Q9VT52 Cluster: Probable insulin-like peptide 3 precurs...    37   0.13 
UniRef50_Q6VVG9 Cluster: Insulin-like peptide 3 precursor; n=4; ...    37   0.18 
UniRef50_UPI00015B5944 Cluster: PREDICTED: similar to LIRP precu...    36   0.23 
UniRef50_UPI0000DB7D6D Cluster: PREDICTED: similar to insulin-li...    36   0.23 
UniRef50_Q673F3 Cluster: Insulin-like growth factor 2; n=7; Mamm...    36   0.31 
UniRef50_Q2LZ98 Cluster: GA20861-PA; n=1; Drosophila pseudoobscu...    36   0.41 
UniRef50_P22334 Cluster: Insulin-like peptide precursor [Contain...    36   0.41 
UniRef50_Q6VVG8 Cluster: Insulin-like peptide 4 precursor; n=2; ...    35   0.54 
UniRef50_A6RW36 Cluster: Putative uncharacterized protein; n=1; ...    34   0.94 
UniRef50_P04667 Cluster: Insulin precursor [Contains: Insulin B ...    34   1.2  
UniRef50_Q6VVH1 Cluster: Insulin-like peptide 1 precursor; n=5; ...    33   1.6  
UniRef50_Q4QI50 Cluster: Putative uncharacterized protein; n=3; ...    33   1.6  
UniRef50_Q9VT53 Cluster: Probable insulin-like peptide 4 precurs...    33   1.6  
UniRef50_Q90325 Cluster: Insulin-like growth factor I, adult for...    33   1.6  
UniRef50_UPI00005464FF Cluster: PREDICTED: similar to insulin-li...    33   2.2  
UniRef50_Q17MN7 Cluster: Putative uncharacterized protein; n=1; ...    33   2.2  
UniRef50_P01344 Cluster: Insulin-like growth factor II precursor...    33   2.2  
UniRef50_Q2QAJ9 Cluster: Preproinsulin 2; n=1; Danio rerio|Rep: ...    33   2.9  
UniRef50_A1XP48 Cluster: Insulin-like 0; n=1; Aplysia californic...    33   2.9  
UniRef50_Q2LZ97 Cluster: GA12803-PA; n=1; Drosophila pseudoobscu...    32   3.8  
UniRef50_Q90WW4 Cluster: Insulin-like growth factor II-A precurs...    32   3.8  
UniRef50_A3SD91 Cluster: Putative beta-lactamase; n=3; Rhodobact...    32   5.0  
UniRef50_P05019 Cluster: Insulin-like growth factor IB precursor...    32   5.0  
UniRef50_O73727 Cluster: Insulin precursor [Contains: Insulin B ...    31   6.6  
UniRef50_Q02816 Cluster: Insulin-like growth factor II precursor...    31   6.6  
UniRef50_UPI000156159C Cluster: PREDICTED: similar to insulin-li...    31   8.7  
UniRef50_Q91443 Cluster: Insulin-like growth factor II precursor...    31   8.7  
UniRef50_Q9K647 Cluster: NAD(P)H oxidoreductase; n=3; Bacillacea...    31   8.7  
UniRef50_Q7XPG9 Cluster: OSJNBb0003B01.14 protein; n=20; Oryza s...    31   8.7  
UniRef50_Q2LZ99 Cluster: GA19821-PA; n=1; Drosophila pseudoobscu...    31   8.7  
UniRef50_Q17MN6 Cluster: Putative uncharacterized protein; n=1; ...    31   8.7  
UniRef50_P24856 Cluster: Ice-structuring glycoprotein precursor ...    31   8.7  

>UniRef50_P26735 Cluster: Bombyxin C-2 precursor (BBX-C2)
           (4K-prothoracicotropic hormone) (4K- PTTH) [Contains:
           Bombyxin C-2 B chain; Bombyxin C-2 A chain]; n=12;
           Bombyx mori|Rep: Bombyxin C-2 precursor (BBX-C2)
           (4K-prothoracicotropic hormone) (4K- PTTH) [Contains:
           Bombyxin C-2 B chain; Bombyxin C-2 A chain] - Bombyx
           mori (Silk moth)
          Length = 95

 Score = 95.5 bits (227), Expect = 4e-19
 Identities = 44/90 (48%), Positives = 53/90 (58%)
 Frame = +3

Query: 69  MKLLGFFLSWVSVCAIVSASEEGHIYCGRYLAYKMADLCWRAGFEKRSVAHYAGYGWPLL 248
           MKL+   +   ++  +  A      YCG +LA  M+ LCW     KRS + YAGYGWP L
Sbjct: 1   MKLVILLVVVSAMLVLGGAQTASQFYCGDFLARTMSILCW-PDMPKRSGSQYAGYGWPWL 59

Query: 249 PSLSEERGKRGIADECCLQPCTNDVLLSYC 338
           P  S  RGKRGI DECC +PCT DVL  YC
Sbjct: 60  PPFSSSRGKRGIVDECCYRPCTTDVLKLYC 89


>UniRef50_O61271 Cluster: Bombyxin G-1 precursor (BBX-G1) [Contains:
           Bombyxin G-1 B chain; Bombyxin G-1 A chain]; n=2; Bombyx
           mori|Rep: Bombyxin G-1 precursor (BBX-G1) [Contains:
           Bombyxin G-1 B chain; Bombyxin G-1 A chain] - Bombyx
           mori (Silk moth)
          Length = 90

 Score = 93.1 bits (221), Expect = 2e-18
 Identities = 49/92 (53%), Positives = 61/92 (66%), Gaps = 2/92 (2%)
 Frame = +3

Query: 69  MKLLGFFLSWVSVCAIVSASEE-GHIYCGRYLAYKMADLCWRAGFEKRSVAHYAGYGWPL 245
           MKL+ F +  +++    S  +E    YCGR+LA  MADLC+   F+KR+   Y GY WPL
Sbjct: 1   MKLIIFVVFCITIYGSTSGQQEVARRYCGRHLAVTMADLCFGVQFDKRNT-QYEGYHWPL 59

Query: 246 LPSLSEERGKR-GIADECCLQPCTNDVLLSYC 338
           L + SEER KR GIADECCL PCT +VL SYC
Sbjct: 60  L-AYSEERIKRQGIADECCLVPCTTNVLSSYC 90


>UniRef50_P21808 Cluster: Bombyxin E-1 precursor (BBX-E1) (Bombyxin
           IV) (4K-prothoracicotropic hormone IV) (4K-PTTH-IV)
           [Contains: Bombyxin E-1 B chain; Bombyxin E-1 A chain];
           n=1; Bombyx mori|Rep: Bombyxin E-1 precursor (BBX-E1)
           (Bombyxin IV) (4K-prothoracicotropic hormone IV)
           (4K-PTTH-IV) [Contains: Bombyxin E-1 B chain; Bombyxin
           E-1 A chain] - Bombyx mori (Silk moth)
          Length = 98

 Score = 88.2 bits (209), Expect = 5e-17
 Identities = 40/84 (47%), Positives = 52/84 (61%), Gaps = 6/84 (7%)
 Frame = +3

Query: 105 VCAIVSASEEGHIYCGRYLAYKMADLCWRAGFEKR---SVAHYAGYGWPLLPSLSEER-- 269
           +C     +   H YCGR+LA  +ADLCW    EKR   S+A Y+  GWP LP+ +  +  
Sbjct: 15  LCIAAQEANVAHHYCGRHLANTLADLCWDTSVEKRSESSLASYSSRGWPWLPTPNFNKRA 74

Query: 270 -GKRGIADECCLQPCTNDVLLSYC 338
             KRG+ DECC+QPCT DVL +YC
Sbjct: 75  IKKRGVVDECCIQPCTLDVLATYC 98


>UniRef50_P91896 Cluster: Bombyxin F-1 precursor (BBX-F1) [Contains:
           Bombyxin F-1 B chain; Bombyxin F-1 A chain]; n=2; Bombyx
           mori|Rep: Bombyxin F-1 precursor (BBX-F1) [Contains:
           Bombyxin F-1 B chain; Bombyxin F-1 A chain] - Bombyx
           mori (Silk moth)
          Length = 95

 Score = 81.4 bits (192), Expect = 6e-15
 Identities = 52/97 (53%), Positives = 58/97 (59%), Gaps = 7/97 (7%)
 Frame = +3

Query: 69  MKLLGFFLSWVSVCAIVSASEEG--HIYCGRYLAYKMADLCW---RAGFEKR-SVAHYAG 230
           MKL+   L  +SV  +VSA E G    YCGR+LA  MA LCW       EKR S   Y  
Sbjct: 1   MKLVVIVLLVISVSILVSAQELGGSRRYCGRHLAQTMAVLCWGIDEMSAEKRNSDMVYED 60

Query: 231 YGWP-LLPSLSEERGKRGIADECCLQPCTNDVLLSYC 338
            G P LLP+  + R KRGI DECCLQ CT DVLLSYC
Sbjct: 61  SGMPELLPA--DTRKKRGIIDECCLQACTRDVLLSYC 95


>UniRef50_O09209 Cluster: Bombyxin-related peptide A precursor
           (ABRP) [Contains: Bombyxin- related peptide A chain B;
           Bombyxin-related peptide A chain A]; n=5;
           Obtectomera|Rep: Bombyxin-related peptide A precursor
           (ABRP) [Contains: Bombyxin- related peptide A chain B;
           Bombyxin-related peptide A chain A] - Agrius convolvuli
           (Morning glory sphinx moth)
          Length = 103

 Score = 65.3 bits (152), Expect = 4e-10
 Identities = 42/102 (41%), Positives = 53/102 (51%), Gaps = 11/102 (10%)
 Frame = +3

Query: 66  IMKLLGFFLSWVSVCAIVSASEEGHI---YCGRYLAYKMADLCWRAGFEK-------RSV 215
           ++ +L  F +  S+ A     EE  I    CGR+LA  +ADLC    +E        RS 
Sbjct: 3   LLVVLCCFFAVYSLAAAQGGQEEFQIKVRICGRHLARTLADLCPNVEYEDVMKRSGARSP 62

Query: 216 AHYAGYGWPLLPSLSEERGKR-GIADECCLQPCTNDVLLSYC 338
           A Y   GWP        RGKR G+AD+CC+  CT DVLLSYC
Sbjct: 63  ALYGTVGWPWARP-GAARGKRAGVADDCCVNSCTMDVLLSYC 103


>UniRef50_P33719 Cluster: Bombyxin A-2 homolog precursor [Contains:
           Bombyxin A-2 homolog B chain; Bombyxin A-2 homolog A
           chain]; n=3; Samia cynthia|Rep: Bombyxin A-2 homolog
           precursor [Contains: Bombyxin A-2 homolog B chain;
           Bombyxin A-2 homolog A chain] - Samia cynthia (Cynthia
           moth) (Ailanthus silkmoth)
          Length = 100

 Score = 60.9 bits (141), Expect = 9e-09
 Identities = 35/89 (39%), Positives = 45/89 (50%), Gaps = 9/89 (10%)
 Frame = +3

Query: 99  VSVCAIVSASEEGHIYCGRYLAYKMADLCWRAGFEKRSV---AHYAGYGWPLLP-----S 254
           V +  + S  +  H+YCGR LA  +  +C      KR     +   GYGW  L       
Sbjct: 10  VVLAVMASGDDTAHVYCGRRLATMLLYVCDNQYQVKRPPYISSENEGYGWKWLERQRARQ 69

Query: 255 LSEERGKR-GIADECCLQPCTNDVLLSYC 338
           L E RGKR GI +ECC +PCT + LL YC
Sbjct: 70  LDEARGKRQGIVEECCNKPCTENELLGYC 98


>UniRef50_Q17196 Cluster: Bombyxin B-11 precursor (BBX-B11)
           (4K-prothoracicotropic hormone) (4K- PTTH) [Contains:
           Bombyxin B-11 B chain; Bombyxin B-11 A chain]; n=12;
           Bombyx mori|Rep: Bombyxin B-11 precursor (BBX-B11)
           (4K-prothoracicotropic hormone) (4K- PTTH) [Contains:
           Bombyxin B-11 B chain; Bombyxin B-11 A chain] - Bombyx
           mori (Silk moth)
          Length = 93

 Score = 54.8 bits (126), Expect = 6e-07
 Identities = 34/92 (36%), Positives = 48/92 (52%), Gaps = 2/92 (2%)
 Frame = +3

Query: 66  IMKLLGFFLSWVSVCAIVSASEE--GHIYCGRYLAYKMADLCWRAGFEKRSVAHYAGYGW 239
           +MK    F+  V +    S+ E+     YCGR+LA  +A +C+  G EKR  A YA Y W
Sbjct: 1   MMKTAVMFILVVVISLTYSSEEQEVARTYCGRHLANILAYVCF--GVEKRGGAQYAPY-W 57

Query: 240 PLLPSLSEERGKRGIADECCLQPCTNDVLLSY 335
               +    R   G+ DECC +PC  +VL S+
Sbjct: 58  Q--ETYLRSRKGPGVVDECCFRPCKLEVLKSF 87


>UniRef50_A0EZS0 Cluster: Insulin-like peptide 6 splice variant A;
           n=3; Aedes aegypti|Rep: Insulin-like peptide 6 splice
           variant A - Aedes aegypti (Yellowfever mosquito)
          Length = 157

 Score = 49.6 bits (113), Expect = 2e-05
 Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 1/65 (1%)
 Frame = +3

Query: 147 CGRYLAYKMADLCW-RAGFEKRSVAHYAGYGWPLLPSLSEERGKRGIADECCLQPCTNDV 323
           CG+YLA +++DLC  R G+ + +               S  R KRGI +ECC Q CT+ +
Sbjct: 28  CGKYLADRISDLCKARGGYSQLTSVESE--------RRSHRRSKRGIVEECCHQSCTDTI 79

Query: 324 LLSYC 338
           L+ YC
Sbjct: 80  LMQYC 84


>UniRef50_A0EZR7 Cluster: Insulin-like peptide 2; n=2; Aedes
           aegypti|Rep: Insulin-like peptide 2 - Aedes aegypti
           (Yellowfever mosquito)
          Length = 167

 Score = 39.1 bits (87), Expect = 0.033
 Identities = 14/24 (58%), Positives = 18/24 (75%)
 Frame = +3

Query: 267 RGKRGIADECCLQPCTNDVLLSYC 338
           +  RGI DECCL+PC+ + LL YC
Sbjct: 140 KSPRGIVDECCLRPCSINQLLKYC 163


>UniRef50_A0EZS2 Cluster: Insulin-like peptide 7; n=1; Aedes
           aegypti|Rep: Insulin-like peptide 7 - Aedes aegypti
           (Yellowfever mosquito)
          Length = 160

 Score = 37.1 bits (82), Expect = 0.13
 Identities = 14/24 (58%), Positives = 18/24 (75%), Gaps = 1/24 (4%)
 Frame = +3

Query: 270 GKRGIADECCLQPCTNDVLL-SYC 338
           GKRG+ D+CC +PCT   LL +YC
Sbjct: 136 GKRGVVDDCCYKPCTLQYLLKNYC 159


>UniRef50_Q9VT52 Cluster: Probable insulin-like peptide 3 precursor
           (Insulin-related peptide) (DILP3) [Contains: Probable
           insulin-like peptide 3 A chain; Probable insulin-like
           peptide 3 B chain]; n=3; Drosophila melanogaster|Rep:
           Probable insulin-like peptide 3 precursor
           (Insulin-related peptide) (DILP3) [Contains: Probable
           insulin-like peptide 3 A chain; Probable insulin-like
           peptide 3 B chain] - Drosophila melanogaster (Fruit fly)
          Length = 120

 Score = 37.1 bits (82), Expect = 0.13
 Identities = 19/48 (39%), Positives = 25/48 (52%)
 Frame = +3

Query: 195 GFEKRSVAHYAGYGWPLLPSLSEERGKRGIADECCLQPCTNDVLLSYC 338
           GFE RS+          +  L   R + G+ DECCL+ CT D +L YC
Sbjct: 68  GFEDRSLLERL-LSDSSVQMLKTRRLRDGVFDECCLKSCTMDEVLRYC 114


>UniRef50_Q6VVG9 Cluster: Insulin-like peptide 3 precursor; n=4;
           Anopheles gambiae|Rep: Insulin-like peptide 3 precursor
           - Anopheles gambiae (African malaria mosquito)
          Length = 160

 Score = 36.7 bits (81), Expect = 0.18
 Identities = 17/40 (42%), Positives = 23/40 (57%)
 Frame = +3

Query: 219 HYAGYGWPLLPSLSEERGKRGIADECCLQPCTNDVLLSYC 338
           H AG+   +     + RG  GI +ECCL+PC  + LL YC
Sbjct: 117 HGAGHNELIPARFRKNRG--GIVEECCLRPCGMNQLLQYC 154


>UniRef50_UPI00015B5944 Cluster: PREDICTED: similar to LIRP
           precursor (Locusta insulin-related peptide); n=1;
           Nasonia vitripennis|Rep: PREDICTED: similar to LIRP
           precursor (Locusta insulin-related peptide) - Nasonia
           vitripennis
          Length = 136

 Score = 36.3 bits (80), Expect = 0.23
 Identities = 13/24 (54%), Positives = 17/24 (70%)
 Frame = +3

Query: 267 RGKRGIADECCLQPCTNDVLLSYC 338
           R  RG+ DECCL+ CT + + SYC
Sbjct: 109 RDSRGVHDECCLKSCTMNEMRSYC 132


>UniRef50_UPI0000DB7D6D Cluster: PREDICTED: similar to insulin-like
           peptide 3 CG14167-PA; n=1; Apis mellifera|Rep:
           PREDICTED: similar to insulin-like peptide 3 CG14167-PA
           - Apis mellifera
          Length = 73

 Score = 36.3 bits (80), Expect = 0.23
 Identities = 13/24 (54%), Positives = 17/24 (70%)
 Frame = +3

Query: 267 RGKRGIADECCLQPCTNDVLLSYC 338
           R  +GI +ECCL+ CT + L SYC
Sbjct: 47  RNSKGIHEECCLKSCTTEELRSYC 70


>UniRef50_Q673F3 Cluster: Insulin-like growth factor 2; n=7;
           Mammalia|Rep: Insulin-like growth factor 2 -
           Ornithorhynchus anatinus (Duckbill platypus)
          Length = 239

 Score = 35.9 bits (79), Expect = 0.31
 Identities = 14/37 (37%), Positives = 21/37 (56%)
 Frame = +3

Query: 228 GYGWPLLPSLSEERGKRGIADECCLQPCTNDVLLSYC 338
           G+ +   PS +  R K+GI +ECC   C   +L +YC
Sbjct: 113 GFYFGRSPSRTNRRSKKGIVEECCFSSCDLALLETYC 149


>UniRef50_Q2LZ98 Cluster: GA20861-PA; n=1; Drosophila
           pseudoobscura|Rep: GA20861-PA - Drosophila pseudoobscura
           (Fruit fly)
          Length = 103

 Score = 35.5 bits (78), Expect = 0.41
 Identities = 13/24 (54%), Positives = 16/24 (66%)
 Frame = +3

Query: 267 RGKRGIADECCLQPCTNDVLLSYC 338
           R ++GIAD CC +PC   VL  YC
Sbjct: 78  RTRQGIADRCCRKPCDISVLTEYC 101


>UniRef50_P22334 Cluster: Insulin-like peptide precursor [Contains:
           Insulin-like peptide B chain; Insulin-like peptide A
           chain]; n=1; Branchiostoma californiense|Rep:
           Insulin-like peptide precursor [Contains: Insulin-like
           peptide B chain; Insulin-like peptide A chain] -
           Branchiostoma californiensis (California lancelet)
           (Amphioxus)
          Length = 305

 Score = 35.5 bits (78), Expect = 0.41
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 9/87 (10%)
 Frame = +3

Query: 105 VCAIVSASEEGHIYCGRYLAYKMADLCWRAGFE---KRSVAHYA------GYGWPLLPSL 257
           VC +V  ++  ++ CG  LA  ++ +C   G+    +RSV+  A            + ++
Sbjct: 15  VCLLVKETQAEYL-CGSTLADVLSFVCGNRGYNSQPRRSVSKRAIDFISEQQAKDYMGAM 73

Query: 258 SEERGKRGIADECCLQPCTNDVLLSYC 338
              R +RG+ +ECC   C    L SYC
Sbjct: 74  PHIRRRRGLVEECCYNVCDYSQLESYC 100


>UniRef50_Q6VVG8 Cluster: Insulin-like peptide 4 precursor; n=2;
           Anopheles gambiae|Rep: Insulin-like peptide 4 precursor
           - Anopheles gambiae (African malaria mosquito)
          Length = 160

 Score = 35.1 bits (77), Expect = 0.54
 Identities = 15/32 (46%), Positives = 22/32 (68%)
 Frame = +3

Query: 243 LLPSLSEERGKRGIADECCLQPCTNDVLLSYC 338
           ++P L + R +R +ADECC + C+   LLSYC
Sbjct: 120 MVPHL-KTRFRRDVADECCREDCSMAQLLSYC 150


>UniRef50_A6RW36 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 297

 Score = 34.3 bits (75), Expect = 0.94
 Identities = 16/46 (34%), Positives = 25/46 (54%)
 Frame = -2

Query: 180 NRPFCMPNNARNICVLLRWLILLRIPKPTTRKNPAISL*Q*VQHNC 43
           N   C+PN    I +LL   ++  +P PT  +NP  +L Q ++H C
Sbjct: 54  NSQSCIPNRPETILLLLSLKLITTLP-PTNPRNPQTALYQAIKHYC 98


>UniRef50_P04667 Cluster: Insulin precursor [Contains: Insulin B
           chain; Insulin A chain]; n=8; Elopocephala|Rep: Insulin
           precursor [Contains: Insulin B chain; Insulin A chain] -
           Oncorhynchus keta (Chum salmon)
          Length = 105

 Score = 33.9 bits (74), Expect = 1.2
 Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 12/86 (13%)
 Frame = +3

Query: 117 VSASEEGHIYCGRYLAYKMADLCWRAGF---EKRSVAHYAGYGWPLLPSLSEERG----- 272
           V A+   H+ CG +L   +  +C   GF    KR V    G+  P     +EE       
Sbjct: 20  VDAAAAQHL-CGSHLVDALYLVCGEKGFFYTPKRDVDPLIGFLSPKSAKENEEYPFKDQT 78

Query: 273 ----KRGIADECCLQPCTNDVLLSYC 338
               KRGI ++CC +PC    L +YC
Sbjct: 79  EMMVKRGIVEQCCHKPCNIFDLQNYC 104


>UniRef50_Q6VVH1 Cluster: Insulin-like peptide 1 precursor; n=5;
           Anopheles gambiae|Rep: Insulin-like peptide 1 precursor
           - Anopheles gambiae (African malaria mosquito)
          Length = 154

 Score = 33.5 bits (73), Expect = 1.6
 Identities = 13/24 (54%), Positives = 15/24 (62%)
 Frame = +3

Query: 267 RGKRGIADECCLQPCTNDVLLSYC 338
           R +R +  ECC Q CT D L SYC
Sbjct: 129 RVRRQVVAECCYQSCTLDTLKSYC 152


>UniRef50_Q4QI50 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 1248

 Score = 33.5 bits (73), Expect = 1.6
 Identities = 13/28 (46%), Positives = 18/28 (64%)
 Frame = +3

Query: 111 AIVSASEEGHIYCGRYLAYKMADLCWRA 194
           A++    EG+ Y GR L YK+A +CW A
Sbjct: 132 AVIVGGVEGNRYWGRELPYKLAKVCWSA 159


>UniRef50_Q9VT53 Cluster: Probable insulin-like peptide 4 precursor
           (Insulin-related peptide) (DILP4) [Contains: Probable
           insulin-like peptide 4 A chain; Probable insulin-like
           peptide 4 B chain]; n=2; melanogaster subgroup|Rep:
           Probable insulin-like peptide 4 precursor
           (Insulin-related peptide) (DILP4) [Contains: Probable
           insulin-like peptide 4 A chain; Probable insulin-like
           peptide 4 B chain] - Drosophila melanogaster (Fruit fly)
          Length = 134

 Score = 33.5 bits (73), Expect = 1.6
 Identities = 13/24 (54%), Positives = 16/24 (66%)
 Frame = +3

Query: 267 RGKRGIADECCLQPCTNDVLLSYC 338
           R +R IA ECC + CT D +L YC
Sbjct: 110 RHRRRIAHECCKEGCTYDDILDYC 133


>UniRef50_Q90325 Cluster: Insulin-like growth factor I, adult form
           precursor; n=27; Clupeocephala|Rep: Insulin-like growth
           factor I, adult form precursor - Cyprinus carpio (Common
           carp)
          Length = 161

 Score = 33.5 bits (73), Expect = 1.6
 Identities = 24/64 (37%), Positives = 27/64 (42%)
 Frame = +3

Query: 147 CGRYLAYKMADLCWRAGFEKRSVAHYAGYGWPLLPSLSEERGKRGIADECCLQPCTNDVL 326
           CG  L   +  +C   GF     +   GYG    PS S     RGI DECC Q C    L
Sbjct: 50  CGAELVDTLQFVCGDRGFY---FSKPTGYG----PS-SRRSHNRGIVDECCFQSCELRRL 101

Query: 327 LSYC 338
             YC
Sbjct: 102 EMYC 105


>UniRef50_UPI00005464FF Cluster: PREDICTED: similar to insulin-like
           growth factor-I; n=2; Danio rerio|Rep: PREDICTED:
           similar to insulin-like growth factor-I - Danio rerio
          Length = 188

 Score = 33.1 bits (72), Expect = 2.2
 Identities = 31/98 (31%), Positives = 38/98 (38%), Gaps = 12/98 (12%)
 Frame = +3

Query: 81  GFFL---SWVSVCAIVSA---------SEEGHIYCGRYLAYKMADLCWRAGFEKRSVAHY 224
           GF L   SW SVC + S          +E     CGR L   +  +C   GF       Y
Sbjct: 14  GFMLKVPSWRSVCVLYSLCCVLILPDNTEGARARCGRELVDDLEFVCGDRGF-------Y 66

Query: 225 AGYGWPLLPSLSEERGKRGIADECCLQPCTNDVLLSYC 338
            G            RGK GI D+CC++ C    L  YC
Sbjct: 67  IGKPGAARSGGPRSRGK-GIVDQCCVRGCDLQHLELYC 103


>UniRef50_Q17MN7 Cluster: Putative uncharacterized protein; n=1;
           Aedes aegypti|Rep: Putative uncharacterized protein -
           Aedes aegypti (Yellowfever mosquito)
          Length = 174

 Score = 33.1 bits (72), Expect = 2.2
 Identities = 14/31 (45%), Positives = 17/31 (54%)
 Frame = +3

Query: 246 LPSLSEERGKRGIADECCLQPCTNDVLLSYC 338
           +P  S  R +R I DECC + CT   L  YC
Sbjct: 142 MPVESYRRVRRQIVDECCRKSCTLKTLKQYC 172


>UniRef50_P01344 Cluster: Insulin-like growth factor II precursor
           (IGF-II) (Somatomedin-A) [Contains: Insulin-like growth
           factor II Ala-25 Del]; n=45; Eutheria|Rep: Insulin-like
           growth factor II precursor (IGF-II) (Somatomedin-A)
           [Contains: Insulin-like growth factor II Ala-25 Del] -
           Homo sapiens (Human)
          Length = 180

 Score = 33.1 bits (72), Expect = 2.2
 Identities = 25/90 (27%), Positives = 40/90 (44%)
 Frame = +3

Query: 69  MKLLGFFLSWVSVCAIVSASEEGHIYCGRYLAYKMADLCWRAGFEKRSVAHYAGYGWPLL 248
           M +L  FL++ S C  ++A       CG  L   +  +C   GF      +++       
Sbjct: 9   MLVLLTFLAFASCC--IAAYRPSETLCGGELVDTLQFVCGDRGF------YFSR------ 54

Query: 249 PSLSEERGKRGIADECCLQPCTNDVLLSYC 338
           P+    R  RGI +ECC + C   +L +YC
Sbjct: 55  PASRVSRRSRGIVEECCFRSCDLALLETYC 84


>UniRef50_Q2QAJ9 Cluster: Preproinsulin 2; n=1; Danio rerio|Rep:
           Preproinsulin 2 - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 107

 Score = 32.7 bits (71), Expect = 2.9
 Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
 Frame = +3

Query: 213 VAHYAGYGWPLLPSLSEE--RGKRGIADECCLQPCTNDVLLSYC 338
           +++ AGY       L E+  + KRGI ++CC +PCT   L  YC
Sbjct: 63  LSNLAGYEAADADPLKEKVMKMKRGIVEQCCHRPCTIYHLEDYC 106


>UniRef50_A1XP48 Cluster: Insulin-like 0; n=1; Aplysia
           californica|Rep: Insulin-like 0 - Aplysia californica
           (California sea hare)
          Length = 262

 Score = 32.7 bits (71), Expect = 2.9
 Identities = 12/19 (63%), Positives = 13/19 (68%)
 Frame = +3

Query: 282 IADECCLQPCTNDVLLSYC 338
           I DECCL+PC    L SYC
Sbjct: 171 IVDECCLRPCNFATLQSYC 189


>UniRef50_Q2LZ97 Cluster: GA12803-PA; n=1; Drosophila
           pseudoobscura|Rep: GA12803-PA - Drosophila pseudoobscura
           (Fruit fly)
          Length = 102

 Score = 32.3 bits (70), Expect = 3.8
 Identities = 12/25 (48%), Positives = 15/25 (60%)
 Frame = +3

Query: 264 ERGKRGIADECCLQPCTNDVLLSYC 338
           +R   GI DECC+  C  + L SYC
Sbjct: 75  QRSSGGIYDECCVYSCRYEELASYC 99


>UniRef50_Q90WW4 Cluster: Insulin-like growth factor II-A precursor;
           n=4; Xenopus|Rep: Insulin-like growth factor II-A
           precursor - Xenopus laevis (African clawed frog)
          Length = 217

 Score = 32.3 bits (70), Expect = 3.8
 Identities = 12/27 (44%), Positives = 16/27 (59%)
 Frame = +3

Query: 258 SEERGKRGIADECCLQPCTNDVLLSYC 338
           S  R  RGI D CC + C  ++L +YC
Sbjct: 90  SNRRPNRGIVDVCCFKSCDLELLETYC 116


>UniRef50_A3SD91 Cluster: Putative beta-lactamase; n=3;
           Rhodobacteraceae|Rep: Putative beta-lactamase -
           Sulfitobacter sp. EE-36
          Length = 388

 Score = 31.9 bits (69), Expect = 5.0
 Identities = 14/44 (31%), Positives = 22/44 (50%)
 Frame = -2

Query: 198 SRHASTNRPFCMPNNARNICVLLRWLILLRIPKPTTRKNPAISL 67
           S H +   P  +P    N+  L+RWL   + P+P TR    +S+
Sbjct: 134 STHVTGGLPLQVPGEVGNVAELIRWLESWQPPQPGTRSYSNVSI 177


>UniRef50_P05019 Cluster: Insulin-like growth factor IB precursor;
           n=157; Gnathostomata|Rep: Insulin-like growth factor IB
           precursor - Homo sapiens (Human)
          Length = 195

 Score = 31.9 bits (69), Expect = 5.0
 Identities = 25/85 (29%), Positives = 33/85 (38%)
 Frame = +3

Query: 84  FFLSWVSVCAIVSASEEGHIYCGRYLAYKMADLCWRAGFEKRSVAHYAGYGWPLLPSLSE 263
           F+L+   +    SA+      CG  L   +  +C   GF         GYG     S S 
Sbjct: 33  FYLALCLLTFTSSATAGPETLCGAELVDALQFVCGDRGFYFNKPT---GYG-----SSSR 84

Query: 264 ERGKRGIADECCLQPCTNDVLLSYC 338
              + GI DECC + C    L  YC
Sbjct: 85  RAPQTGIVDECCFRSCDLRRLEMYC 109


>UniRef50_O73727 Cluster: Insulin precursor [Contains: Insulin B
           chain; Insulin A chain]; n=19; Teleostei|Rep: Insulin
           precursor [Contains: Insulin B chain; Insulin A chain] -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 108

 Score = 31.5 bits (68), Expect = 6.6
 Identities = 11/22 (50%), Positives = 16/22 (72%)
 Frame = +3

Query: 273 KRGIADECCLQPCTNDVLLSYC 338
           KRGI ++CC +PC+   L +YC
Sbjct: 86  KRGIVEQCCHKPCSIFELQNYC 107


>UniRef50_Q02816 Cluster: Insulin-like growth factor II precursor;
           n=73; Euteleostomi|Rep: Insulin-like growth factor II
           precursor - Oncorhynchus mykiss (Rainbow trout) (Salmo
           gairdneri)
          Length = 214

 Score = 31.5 bits (68), Expect = 6.6
 Identities = 13/33 (39%), Positives = 17/33 (51%)
 Frame = +3

Query: 240 PLLPSLSEERGKRGIADECCLQPCTNDVLLSYC 338
           P   S S     RGI +ECC + C  ++L  YC
Sbjct: 78  PTSRSNSRRSQNRGIVEECCFRSCDLNLLEQYC 110


>UniRef50_UPI000156159C Cluster: PREDICTED: similar to insulin-like
           growth factor 2; n=1; Equus caballus|Rep: PREDICTED:
           similar to insulin-like growth factor 2 - Equus caballus
          Length = 199

 Score = 31.1 bits (67), Expect = 8.7
 Identities = 12/30 (40%), Positives = 17/30 (56%)
 Frame = +3

Query: 249 PSLSEERGKRGIADECCLQPCTNDVLLSYC 338
           P+    R  RGI +ECC + C   +L +YC
Sbjct: 73  PASRINRRSRGIVEECCFRSCDLALLETYC 102


>UniRef50_Q91443 Cluster: Insulin-like growth factor II precursor;
           n=1; Squalus acanthias|Rep: Insulin-like growth factor
           II precursor - Squalus acanthias (Spiny dogfish)
          Length = 210

 Score = 31.1 bits (67), Expect = 8.7
 Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 4/47 (8%)
 Frame = +3

Query: 267 RGKRGIADECCLQPCTNDVLLSYC*I----ASSKLTFLYNRVIVHKI 395
           R  RGI +ECC + C   +L +YC +    A S  +    R ++H+I
Sbjct: 87  RQNRGIVEECCFRSCDLLILETYCAVPPEAARSTPSPAQQRTLMHRI 133


>UniRef50_Q9K647 Cluster: NAD(P)H oxidoreductase; n=3;
           Bacillaceae|Rep: NAD(P)H oxidoreductase - Bacillus
           halodurans
          Length = 202

 Score = 31.1 bits (67), Expect = 8.7
 Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 1/72 (1%)
 Frame = +3

Query: 177 DLCWRAGFEK-RSVAHYAGYGWPLLPSLSEERGKRGIADECCLQPCTNDVLLSYC*IASS 353
           D  W  GF    +  H+    W  L  +S+E+ K+   DE  +    N  +  YC +++S
Sbjct: 110 DRVWNNGFAYGANHLHHQHVLWIGLAGVSKEQMKKRNYDEM-ITHLLNVGIADYCGVSNS 168

Query: 354 KLTFLYNRVIVH 389
           K+ FLY  +  H
Sbjct: 169 KVEFLYETLDSH 180


>UniRef50_Q7XPG9 Cluster: OSJNBb0003B01.14 protein; n=20; Oryza
            sativa|Rep: OSJNBb0003B01.14 protein - Oryza sativa
            (Rice)
          Length = 1728

 Score = 31.1 bits (67), Expect = 8.7
 Identities = 12/52 (23%), Positives = 21/52 (40%)
 Frame = +3

Query: 96   WVSVCAIVSASEEGHIYCGRYLAYKMADLCWRAGFEKRSVAHYAGYGWPLLP 251
            W+  C + S+S + H++C +     +   C   G +  S     GY     P
Sbjct: 941  WIVACCVFSSSNQVHVFCHKDTLASVKPFCIDLGAKANSALKRCGYNQVKFP 992


>UniRef50_Q2LZ99 Cluster: GA19821-PA; n=1; Drosophila
           pseudoobscura|Rep: GA19821-PA - Drosophila pseudoobscura
           (Fruit fly)
          Length = 133

 Score = 31.1 bits (67), Expect = 8.7
 Identities = 12/24 (50%), Positives = 15/24 (62%)
 Frame = +3

Query: 267 RGKRGIADECCLQPCTNDVLLSYC 338
           R +R IA ECC   CT + +L YC
Sbjct: 109 RHRRRIAHECCRDGCTYEDILEYC 132


>UniRef50_Q17MN6 Cluster: Putative uncharacterized protein; n=1;
           Aedes aegypti|Rep: Putative uncharacterized protein -
           Aedes aegypti (Yellowfever mosquito)
          Length = 161

 Score = 31.1 bits (67), Expect = 8.7
 Identities = 12/29 (41%), Positives = 20/29 (68%), Gaps = 1/29 (3%)
 Frame = +3

Query: 255 LSEERGKRGIADECCLQPCTND-VLLSYC 338
           L + R  +GI +ECC + CT + ++L+YC
Sbjct: 132 LGKRRPGKGIVEECCRKGCTYEYLMLNYC 160


>UniRef50_P24856 Cluster: Ice-structuring glycoprotein precursor
           (ISGP) (Antifreeze glycopeptide polyprotein) (AFGP
           polyprotein) [Contains: AFGP7 (AFGP 7); AFGP8 (AFGP 8);
           AFGP8-like]; n=21; Holacanthopterygii|Rep:
           Ice-structuring glycoprotein precursor (ISGP)
           (Antifreeze glycopeptide polyprotein) (AFGP polyprotein)
           [Contains: AFGP7 (AFGP 7); AFGP8 (AFGP 8); AFGP8-like] -
           Notothenia coriiceps neglecta (Black rockcod)
           (Yellowbelly rockcod)
          Length = 790

 Score = 31.1 bits (67), Expect = 8.7
 Identities = 16/41 (39%), Positives = 20/41 (48%)
 Frame = +1

Query: 196 ALRSVVSRTTPVTAGRCCLLCRKSAANEASPMNAVFNHART 318
           AL    +  TP TA    L+   +AA  A+P  A FN A T
Sbjct: 478 ALNFAATAATPATAATPALIFAATAATAATPATAAFNFAAT 518



 Score = 31.1 bits (67), Expect = 8.7
 Identities = 16/41 (39%), Positives = 20/41 (48%)
 Frame = +1

Query: 196 ALRSVVSRTTPVTAGRCCLLCRKSAANEASPMNAVFNHART 318
           AL    +  TP TA    L+   +AA  A+P  A FN A T
Sbjct: 682 ALNFAATAATPATAATPALIFAATAATAATPATAAFNFAAT 722


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 400,374,996
Number of Sequences: 1657284
Number of extensions: 7624025
Number of successful extensions: 20064
Number of sequences better than 10.0: 42
Number of HSP's better than 10.0 without gapping: 19481
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 20051
length of database: 575,637,011
effective HSP length: 92
effective length of database: 423,166,883
effective search space used: 17773009086
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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